DFR86_05245 2df097048688fe785eb49850f03d2468 130 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 130 2.1E-20 T 31-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 DFR86_05245 2df097048688fe785eb49850f03d2468 130 SUPERFAMILY SSF46785 6 85 3.71E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_05245 2df097048688fe785eb49850f03d2468 130 SUPERFAMILY SSF47979 63 130 1.57E-17 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 DFR86_05245 2df097048688fe785eb49850f03d2468 130 Gene3D G3DSA:1.10.10.10 1 130 5.8E-41 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_05245 2df097048688fe785eb49850f03d2468 130 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 9 57 6.0E-5 T 31-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 DFR86_05245 2df097048688fe785eb49850f03d2468 130 SMART SM00529 25 122 3.5E-11 T 31-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 DFR86_06295 92a5e7b6cd0a58f06073e23145311c0c 237 Pfam PF00156 Phosphoribosyl transferase domain 114 225 4.2E-13 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR86_06295 92a5e7b6cd0a58f06073e23145311c0c 237 SUPERFAMILY SSF53271 75 219 1.24E-28 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR86_06295 92a5e7b6cd0a58f06073e23145311c0c 237 Gene3D G3DSA:3.40.50.2020 63 233 1.5E-33 T 31-10-2018 DFR86_03325 dc3e713d69d1c2499899ccc49c935744 261 Gene3D G3DSA:3.40.50.1000 8 257 1.6E-72 T 31-10-2018 IPR023214 HAD superfamily DFR86_03325 dc3e713d69d1c2499899ccc49c935744 261 PIRSF PIRSF000915 1 261 6.2E-57 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA DFR86_03325 dc3e713d69d1c2499899ccc49c935744 261 Gene3D G3DSA:3.40.50.1000 84 186 1.6E-72 T 31-10-2018 IPR023214 HAD superfamily DFR86_03325 dc3e713d69d1c2499899ccc49c935744 261 Pfam PF13242 HAD-hyrolase-like 186 259 5.5E-19 T 31-10-2018 DFR86_03325 dc3e713d69d1c2499899ccc49c935744 261 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 3.6E-24 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA DFR86_03325 dc3e713d69d1c2499899ccc49c935744 261 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 236 1.6E-42 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA DFR86_03325 dc3e713d69d1c2499899ccc49c935744 261 SUPERFAMILY SSF56784 3 260 3.71E-62 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 Pfam PF00106 short chain dehydrogenase 2 175 1.4E-45 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 SUPERFAMILY SSF51735 2 226 1.12E-58 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 127 2.8E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 156 2.8E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 2.8E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 2.8E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 64 75 2.8E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 64 75 1.3E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 125 1.3E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 156 1.3E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09065 fa57a41ef04ceb0c57b574bd4a90fd2e 245 Gene3D G3DSA:3.40.50.720 1 244 8.0E-58 T 31-10-2018 DFR86_07420 6446c9ef7b77134177b7e4f2d63f8187 124 Gene3D G3DSA:3.30.1330.40 1 123 5.5E-53 T 31-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 DFR86_07420 6446c9ef7b77134177b7e4f2d63f8187 124 SUPERFAMILY SSF55298 1 124 2.2E-45 T 31-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 DFR86_07420 6446c9ef7b77134177b7e4f2d63f8187 124 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 100 118 - T 31-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 DFR86_07420 6446c9ef7b77134177b7e4f2d63f8187 124 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 123 5.2E-50 T 31-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 DFR86_07420 6446c9ef7b77134177b7e4f2d63f8187 124 Pfam PF01042 Endoribonuclease L-PSP 9 124 1.8E-42 T 31-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 DFR86_03280 7c3ae693b369299129cac5383fd26987 538 Gene3D G3DSA:2.170.190.11 54 143 5.0E-100 T 31-10-2018 DFR86_03280 7c3ae693b369299129cac5383fd26987 538 SUPERFAMILY SSF63867 328 393 3.76E-8 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_03280 7c3ae693b369299129cac5383fd26987 538 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 306 1.5E-30 T 31-10-2018 IPR001453 MoaB/Mog domain DFR86_03280 7c3ae693b369299129cac5383fd26987 538 Gene3D G3DSA:3.90.105.10 30 176 5.0E-100 T 31-10-2018 DFR86_03280 7c3ae693b369299129cac5383fd26987 538 SMART SM00852 182 320 7.8E-35 T 31-10-2018 IPR001453 MoaB/Mog domain DFR86_03280 7c3ae693b369299129cac5383fd26987 538 Pfam PF03454 MoeA C-terminal region (domain IV) 331 392 2.5E-7 T 31-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_03280 7c3ae693b369299129cac5383fd26987 538 Gene3D G3DSA:3.40.980.10 177 325 5.0E-100 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR86_03280 7c3ae693b369299129cac5383fd26987 538 Pfam PF00994 Probable molybdopterin binding domain 184 317 1.4E-27 T 31-10-2018 IPR001453 MoaB/Mog domain DFR86_03280 7c3ae693b369299129cac5383fd26987 538 Gene3D G3DSA:2.40.340.10 326 388 5.0E-100 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_03280 7c3ae693b369299129cac5383fd26987 538 Pfam PF03453 MoeA N-terminal region (domain I and II) 12 169 3.3E-35 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_03280 7c3ae693b369299129cac5383fd26987 538 SUPERFAMILY SSF63882 9 176 3.79E-46 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_03280 7c3ae693b369299129cac5383fd26987 538 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 255 288 - T 31-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 DFR86_03280 7c3ae693b369299129cac5383fd26987 538 SUPERFAMILY SSF53218 179 318 1.44E-38 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR86_04370 c86531c5cd23862ee91b628f7c094b53 129 Pfam PF06157 Protein of unknown function (DUF973) 33 123 1.5E-13 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR86_00235 5478d1b4801d4b69715a4a8e5c23ab1a 269 Gene3D G3DSA:3.60.20.10 1 223 7.7E-74 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_00235 5478d1b4801d4b69715a4a8e5c23ab1a 269 Pfam PF08823 Putative peptidoglycan binding domain 213 264 4.6E-13 T 31-10-2018 IPR014927 Putative peptidoglycan binding DFR86_00235 5478d1b4801d4b69715a4a8e5c23ab1a 269 Pfam PF06267 Family of unknown function (DUF1028) 2 200 1.1E-70 T 31-10-2018 IPR010430 Protein of unknown function DUF1028 DFR86_00235 5478d1b4801d4b69715a4a8e5c23ab1a 269 SUPERFAMILY SSF56235 1 232 9.26E-68 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_07620 02954e045763dc2f5a5c101796cb4676 349 SUPERFAMILY SSF52540 61 338 3.48E-67 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07620 02954e045763dc2f5a5c101796cb4676 349 Pfam PF00270 DEAD/DEAH box helicase 22 179 4.6E-43 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_07620 02954e045763dc2f5a5c101796cb4676 349 SMART SM00490 238 318 1.1E-30 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_07620 02954e045763dc2f5a5c101796cb4676 349 Pfam PF00271 Helicase conserved C-terminal domain 218 318 1.7E-30 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_07620 02954e045763dc2f5a5c101796cb4676 349 Gene3D G3DSA:3.40.50.300 198 349 1.7E-50 T 31-10-2018 DFR86_07620 02954e045763dc2f5a5c101796cb4676 349 SMART SM00487 17 201 4.0E-53 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_07620 02954e045763dc2f5a5c101796cb4676 349 Gene3D G3DSA:3.40.50.300 2 193 2.4E-62 T 31-10-2018 DFR86_03995 7ef2a3c1736e488bc92feb83cec9fbc8 340 Pfam PF02769 AIR synthase related protein, C-terminal domain 167 307 9.0E-21 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR86_03995 7ef2a3c1736e488bc92feb83cec9fbc8 340 Pfam PF00586 AIR synthase related protein, N-terminal domain 45 156 2.9E-14 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR86_03995 7ef2a3c1736e488bc92feb83cec9fbc8 340 SUPERFAMILY SSF56042 163 334 2.54E-32 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_03995 7ef2a3c1736e488bc92feb83cec9fbc8 340 Gene3D G3DSA:3.90.650.10 161 340 8.4E-41 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_03995 7ef2a3c1736e488bc92feb83cec9fbc8 340 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 4 340 2.6E-106 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE DFR86_03995 7ef2a3c1736e488bc92feb83cec9fbc8 340 Gene3D G3DSA:3.30.1330.10 1 157 2.0E-39 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_03995 7ef2a3c1736e488bc92feb83cec9fbc8 340 SUPERFAMILY SSF55326 4 160 9.12E-29 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_03995 7ef2a3c1736e488bc92feb83cec9fbc8 340 PIRSF PIRSF005644 1 340 2.7E-95 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE DFR86_09080 b8ff5329f12b8ec7f056a1f991cf3d88 302 PIRSF PIRSF001439 1 302 1.2E-56 T 31-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 DFR86_09080 b8ff5329f12b8ec7f056a1f991cf3d88 302 Gene3D G3DSA:3.40.50.720 120 281 6.0E-69 T 31-10-2018 DFR86_09080 b8ff5329f12b8ec7f056a1f991cf3d88 302 Gene3D G3DSA:3.30.1780.10 4 297 6.0E-69 T 31-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 DFR86_09080 b8ff5329f12b8ec7f056a1f991cf3d88 302 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 3 295 4.6E-43 T 31-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 DFR86_09080 b8ff5329f12b8ec7f056a1f991cf3d88 302 SUPERFAMILY SSF51735 1 297 5.73E-70 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_03490 98c4619317c97d0f1f4d0b12736ca443 278 Pfam PF12679 ABC-2 family transporter protein 8 273 8.9E-13 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 DFR86_08865 305754eecf7ebc673062c69451200618 347 SUPERFAMILY SSF48179 252 345 5.44E-7 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_08865 305754eecf7ebc673062c69451200618 347 SMART SM00830 9 89 2.8E-24 T 31-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 DFR86_08865 305754eecf7ebc673062c69451200618 347 SUPERFAMILY SSF51735 89 247 4.97E-15 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_08865 305754eecf7ebc673062c69451200618 347 Gene3D G3DSA:3.40.50.720 94 258 5.3E-15 T 31-10-2018 DFR86_08865 305754eecf7ebc673062c69451200618 347 SUPERFAMILY SSF48600 4 88 1.37E-21 T 31-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 DFR86_08865 305754eecf7ebc673062c69451200618 347 TIGRFAM TIGR01791 CM_archaeal: chorismate mutase 5 84 4.0E-22 T 31-10-2018 IPR010950 Chorismate mutase, archaeal KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 DFR86_08865 305754eecf7ebc673062c69451200618 347 Pfam PF02153 Prephenate dehydrogenase 117 306 6.3E-18 T 31-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 DFR86_08865 305754eecf7ebc673062c69451200618 347 Gene3D G3DSA:1.20.59.10 1 93 1.5E-21 T 31-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 DFR86_08865 305754eecf7ebc673062c69451200618 347 Pfam PF01817 Chorismate mutase type II 9 86 4.9E-17 T 31-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 DFR86_05555 c3242cc31ed09165768eb95a61782bd0 590 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 20 465 1.5E-74 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_05555 c3242cc31ed09165768eb95a61782bd0 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 422 443 3.0E-8 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_05555 c3242cc31ed09165768eb95a61782bd0 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 238 259 3.0E-8 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_05555 c3242cc31ed09165768eb95a61782bd0 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 371 390 3.0E-8 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_05555 c3242cc31ed09165768eb95a61782bd0 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 308 329 3.0E-8 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_05555 c3242cc31ed09165768eb95a61782bd0 590 SUPERFAMILY SSF81442 19 489 4.97E-95 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_05555 c3242cc31ed09165768eb95a61782bd0 590 Gene3D G3DSA:1.20.210.10 13 516 2.8E-84 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_07630 38ad0f8491fe3f39f3f041729cebde64 403 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 299 379 7.2E-15 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR86_07630 38ad0f8491fe3f39f3f041729cebde64 403 Pfam PF04055 Radical SAM superfamily 75 219 6.0E-15 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_07630 38ad0f8491fe3f39f3f041729cebde64 403 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 75 86 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_07630 38ad0f8491fe3f39f3f041729cebde64 403 SUPERFAMILY SSF102114 73 371 3.66E-43 T 31-10-2018 DFR86_07630 38ad0f8491fe3f39f3f041729cebde64 403 Pfam PF13353 4Fe-4S single cluster domain 73 190 3.2E-10 T 31-10-2018 DFR86_07630 38ad0f8491fe3f39f3f041729cebde64 403 Gene3D G3DSA:3.20.20.70 71 402 1.3E-55 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 6 297 8.9E-99 T 31-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 SUPERFAMILY SSF55920 2 297 8.51E-64 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 80 96 - T 31-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 SUPERFAMILY SSF46785 197 273 5.71E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 Pfam PF00557 Metallopeptidase family M24 10 289 1.0E-39 T 31-10-2018 IPR000994 Peptidase M24 DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 Hamap MF_01975 Methionine aminopeptidase [map]. 6 297 45.48 T 31-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 Gene3D G3DSA:3.90.230.10 11 288 1.2E-94 T 31-10-2018 DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 147 159 3.4E-14 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 80 96 3.4E-14 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 55 68 3.4E-14 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 178 190 3.4E-14 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR86_05680 b515a3552ef380b3517a7a10325b604d 297 Gene3D G3DSA:1.10.10.10 197 274 1.2E-94 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_02425 df4df7566d453dd845fc4f9d666b6176 991 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 516 527 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_02425 df4df7566d453dd845fc4f9d666b6176 991 Pfam PF01565 FAD binding domain 46 182 1.9E-34 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_02425 df4df7566d453dd845fc4f9d666b6176 991 SUPERFAMILY SSF46548 511 600 2.09E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_02425 df4df7566d453dd845fc4f9d666b6176 991 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 572 583 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_02425 df4df7566d453dd845fc4f9d666b6176 991 Gene3D G3DSA:3.30.465.40 12 226 3.5E-44 T 31-10-2018 DFR86_02425 df4df7566d453dd845fc4f9d666b6176 991 SUPERFAMILY SSF56176 38 208 3.04E-44 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_02425 df4df7566d453dd845fc4f9d666b6176 991 Pfam PF13534 4Fe-4S dicluster domain 516 586 1.1E-8 T 31-10-2018 DFR86_02425 df4df7566d453dd845fc4f9d666b6176 991 Gene3D G3DSA:1.10.1060.10 503 603 1.7E-8 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_02425 df4df7566d453dd845fc4f9d666b6176 991 SUPERFAMILY SSF55103 281 460 1.96E-5 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DFR86_08915 4e9e1e3972ff42b399f789bff6e2df86 90 SUPERFAMILY SSF55257 2 88 3.14E-23 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_08915 4e9e1e3972ff42b399f789bff6e2df86 90 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 31-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 DFR86_08915 4e9e1e3972ff42b399f789bff6e2df86 90 Gene3D G3DSA:3.30.1360.10 1 90 4.4E-28 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_08915 4e9e1e3972ff42b399f789bff6e2df86 90 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 85 3.9E-20 T 31-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 DFR86_08915 4e9e1e3972ff42b399f789bff6e2df86 90 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 87 18.729 T 31-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06055 28bfdb73f9d9457a28658a25381878cf 175 Pfam PF00575 S1 RNA binding domain 81 147 6.7E-14 T 31-10-2018 IPR003029 S1 domain GO:0003676 DFR86_06055 28bfdb73f9d9457a28658a25381878cf 175 Gene3D G3DSA:2.40.50.140 82 175 4.4E-22 T 31-10-2018 DFR86_06055 28bfdb73f9d9457a28658a25381878cf 175 SMART SM00316 80 166 4.2E-11 T 31-10-2018 IPR022967 RNA-binding domain, S1 DFR86_06055 28bfdb73f9d9457a28658a25381878cf 175 Gene3D G3DSA:3.30.1490.120 1 81 4.0E-26 T 31-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 DFR86_06055 28bfdb73f9d9457a28658a25381878cf 175 SUPERFAMILY SSF88798 1 77 1.7E-18 T 31-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 DFR86_06055 28bfdb73f9d9457a28658a25381878cf 175 SUPERFAMILY SSF50249 82 172 2.01E-19 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_06055 28bfdb73f9d9457a28658a25381878cf 175 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 10 77 1.1E-14 T 31-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 DFR86_06055 28bfdb73f9d9457a28658a25381878cf 175 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 174 7.2E-54 T 31-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 SUPERFAMILY SSF55957 361 454 3.66E-22 T 31-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 370 1.6E-18 T 31-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 154 254 1.5E-22 T 31-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 91 100 - T 31-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 Gene3D G3DSA:3.30.310.50 371 453 2.7E-25 T 31-10-2018 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 SUPERFAMILY SSF53738 3 178 2.98E-42 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 1.3E-42 T 31-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 SUPERFAMILY SSF53738 153 256 3.1E-24 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 SUPERFAMILY SSF53738 242 371 1.57E-16 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 388 450 9.0E-10 T 31-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 4.1E-15 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 90 104 4.1E-15 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 4.1E-15 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 4.1E-15 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 451 4.2E-162 T 31-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 Gene3D G3DSA:3.40.120.10 162 358 3.2E-65 T 31-10-2018 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 Gene3D G3DSA:3.40.120.10 255 363 3.2E-65 T 31-10-2018 DFR86_06990 5889d2a85d412c703c22b53170312e84 455 Gene3D G3DSA:3.40.120.10 1 150 2.3E-54 T 31-10-2018 DFR86_06180 fb43802f7a69d2acee0520f9a579dd49 245 Gene3D G3DSA:2.30.130.70 163 241 1.4E-82 T 31-10-2018 DFR86_06180 fb43802f7a69d2acee0520f9a579dd49 245 SUPERFAMILY SSF55120 1 160 6.62E-43 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 DFR86_06180 fb43802f7a69d2acee0520f9a579dd49 245 Pfam PF01472 PUA domain 163 233 3.8E-16 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR86_06180 fb43802f7a69d2acee0520f9a579dd49 245 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 94 157 1.2E-24 T 31-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 DFR86_06180 fb43802f7a69d2acee0520f9a579dd49 245 SUPERFAMILY SSF88697 163 241 3.09E-17 T 31-10-2018 IPR015947 PUA-like superfamily DFR86_06180 fb43802f7a69d2acee0520f9a579dd49 245 Gene3D G3DSA:3.30.70.3190 17 119 1.4E-82 T 31-10-2018 DFR86_06180 fb43802f7a69d2acee0520f9a579dd49 245 SMART SM00359 163 234 1.2E-11 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR86_06180 fb43802f7a69d2acee0520f9a579dd49 245 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 1 244 1.1E-87 T 31-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 DFR86_06180 fb43802f7a69d2acee0520f9a579dd49 245 Gene3D G3DSA:3.30.2350.10 1 162 1.4E-82 T 31-10-2018 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 334 350 1.4E-29 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 295 312 1.4E-29 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 396 411 1.4E-29 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 422 435 1.4E-29 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 SUPERFAMILY SSF51556 130 557 4.54E-163 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 Pfam PF01979 Amidohydrolase family 126 444 6.3E-57 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 2 557 3.7E-243 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 Gene3D G3DSA:3.20.20.140 130 557 1.2E-246 T 31-10-2018 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 SUPERFAMILY SSF51338 1 469 8.24E-53 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 Hamap MF_01953 Urease subunit alpha [ureC]. 1 557 50.9 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 Gene3D G3DSA:2.30.40.10 3 475 1.2E-246 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04335 ec0a1c5455941d4d2a8933457d1612eb 557 Pfam PF00449 Urease alpha-subunit, N-terminal domain 1 120 2.1E-46 T 31-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_03225 927fab20e75937cd0c5360834b629ab8 418 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 2 415 4.3E-125 T 31-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 DFR86_03225 927fab20e75937cd0c5360834b629ab8 418 Pfam PF00919 Uncharacterized protein family UPF0004 2 93 2.4E-21 T 31-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 DFR86_03225 927fab20e75937cd0c5360834b629ab8 418 Gene3D G3DSA:3.80.30.20 129 363 2.2E-73 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe DFR86_03225 927fab20e75937cd0c5360834b629ab8 418 SUPERFAMILY SSF102114 124 360 1.11E-47 T 31-10-2018 DFR86_03225 927fab20e75937cd0c5360834b629ab8 418 Pfam PF01938 TRAM domain 361 417 1.7E-6 T 31-10-2018 IPR002792 TRAM domain DFR86_03225 927fab20e75937cd0c5360834b629ab8 418 SMART SM00729 130 349 7.0E-50 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_03225 927fab20e75937cd0c5360834b629ab8 418 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 414 9.4E-124 T 31-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 DFR86_03225 927fab20e75937cd0c5360834b629ab8 418 Gene3D G3DSA:3.40.50.12160 1 128 8.3E-24 T 31-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily DFR86_03225 927fab20e75937cd0c5360834b629ab8 418 Pfam PF04055 Radical SAM superfamily 134 307 7.3E-24 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_09240 34e7e9f79d514e6dd9e9758a22c31688 59 Gene3D G3DSA:1.20.5.820 1 59 9.9E-13 T 31-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_09240 34e7e9f79d514e6dd9e9758a22c31688 59 Hamap MF_00422 Protein translocase subunit SecE [secE]. 5 58 10.561 T 31-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_09240 34e7e9f79d514e6dd9e9758a22c31688 59 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 4 57 6.0E-10 T 31-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_09240 34e7e9f79d514e6dd9e9758a22c31688 59 SUPERFAMILY SSF103456 4 57 4.58E-14 T 31-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_00890 834081bfa88adfa4e64aadef87efe482 328 SUPERFAMILY SSF51735 1 310 5.44E-92 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_00890 834081bfa88adfa4e64aadef87efe482 328 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 298 1.4E-76 T 31-10-2018 IPR016040 NAD(P)-binding domain DFR86_00890 834081bfa88adfa4e64aadef87efe482 328 Gene3D G3DSA:3.40.50.720 4 289 1.4E-112 T 31-10-2018 DFR86_00890 834081bfa88adfa4e64aadef87efe482 328 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 313 8.7E-129 T 31-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 DFR86_00890 834081bfa88adfa4e64aadef87efe482 328 Gene3D G3DSA:3.90.25.10 173 305 1.4E-112 T 31-10-2018 DFR86_00765 985e60534ffb22c79769557e74a8307f 324 SUPERFAMILY SSF52540 1 240 2.08E-82 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00765 985e60534ffb22c79769557e74a8307f 324 Gene3D G3DSA:3.40.50.300 1 235 1.8E-76 T 31-10-2018 DFR86_00765 985e60534ffb22c79769557e74a8307f 324 SMART SM00382 26 210 1.1E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_00765 985e60534ffb22c79769557e74a8307f 324 Gene3D G3DSA:2.40.50.100 247 311 1.6E-5 T 31-10-2018 DFR86_00765 985e60534ffb22c79769557e74a8307f 324 Gene3D G3DSA:2.40.50.140 256 310 1.6E-5 T 31-10-2018 DFR86_00765 985e60534ffb22c79769557e74a8307f 324 Pfam PF00005 ABC transporter 17 159 1.7E-34 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_00765 985e60534ffb22c79769557e74a8307f 324 SUPERFAMILY SSF50331 236 309 1.26E-7 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal DFR86_00765 985e60534ffb22c79769557e74a8307f 324 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_10280 0cbf327a284964cd18905551ea0b88e3 497 SUPERFAMILY SSF52518 353 495 4.32E-21 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_10280 0cbf327a284964cd18905551ea0b88e3 497 Gene3D G3DSA:3.40.50.970 3 170 8.1E-42 T 31-10-2018 DFR86_10280 0cbf327a284964cd18905551ea0b88e3 497 SUPERFAMILY SSF52467 182 318 1.13E-21 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_10280 0cbf327a284964cd18905551ea0b88e3 497 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 166 2.7E-31 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR86_10280 0cbf327a284964cd18905551ea0b88e3 497 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 485 1.4E-14 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR86_10280 0cbf327a284964cd18905551ea0b88e3 497 Gene3D G3DSA:3.40.50.1220 179 325 2.7E-19 T 31-10-2018 DFR86_10280 0cbf327a284964cd18905551ea0b88e3 497 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 316 1.2E-15 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DFR86_10280 0cbf327a284964cd18905551ea0b88e3 497 Gene3D G3DSA:3.40.50.970 339 497 5.4E-21 T 31-10-2018 DFR86_10280 0cbf327a284964cd18905551ea0b88e3 497 SUPERFAMILY SSF52518 12 173 3.34E-31 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_09780 13561d548aa490a9ed731f8f97ea9d77 230 SUPERFAMILY SSF158372 5 75 1.44E-17 T 31-10-2018 IPR036809 AF1782-like superfamily DFR86_09780 13561d548aa490a9ed731f8f97ea9d77 230 Pfam PF01467 Cytidylyltransferase-like 91 218 2.8E-17 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR86_09780 13561d548aa490a9ed731f8f97ea9d77 230 SUPERFAMILY SSF52374 87 219 3.1E-19 T 31-10-2018 DFR86_09780 13561d548aa490a9ed731f8f97ea9d77 230 Gene3D G3DSA:1.20.1270.90 2 83 3.0E-20 T 31-10-2018 DFR86_09780 13561d548aa490a9ed731f8f97ea9d77 230 Gene3D G3DSA:3.40.50.620 86 206 3.8E-33 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_09780 13561d548aa490a9ed731f8f97ea9d77 230 Pfam PF04010 Protein of unknown function (DUF357) 10 73 7.3E-15 T 31-10-2018 IPR023140 Domain of unknown function DUF357 DFR86_09780 13561d548aa490a9ed731f8f97ea9d77 230 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 89 151 1.1E-16 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR86_09835 42d6220b5716e099db00c4e95ea6bc67 98 Pfam PF01918 Alba 10 72 3.2E-22 T 31-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 DFR86_09835 42d6220b5716e099db00c4e95ea6bc67 98 PIRSF PIRSF028732 6 97 1.6E-36 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 DFR86_09835 42d6220b5716e099db00c4e95ea6bc67 98 SUPERFAMILY SSF82704 10 96 5.1E-28 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 DFR86_09835 42d6220b5716e099db00c4e95ea6bc67 98 Gene3D G3DSA:3.30.110.20 1 97 1.5E-34 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 DFR86_09835 42d6220b5716e099db00c4e95ea6bc67 98 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 10 96 1.1E-35 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 DFR86_09835 42d6220b5716e099db00c4e95ea6bc67 98 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 96 27.598 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 DFR86_09835 42d6220b5716e099db00c4e95ea6bc67 98 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 13 97 6.0E-38 T 31-10-2018 DFR86_02115 c58e899f15596e1218ab3c9d0a3ff826 171 Gene3D G3DSA:3.90.550.10 2 168 1.9E-27 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_02115 c58e899f15596e1218ab3c9d0a3ff826 171 SUPERFAMILY SSF53448 2 122 4.06E-22 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_02115 c58e899f15596e1218ab3c9d0a3ff826 171 Pfam PF12804 MobA-like NTP transferase domain 3 117 8.2E-11 T 31-10-2018 IPR025877 MobA-like NTP transferase DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 Gene3D G3DSA:3.40.50.970 1 178 1.9E-66 T 31-10-2018 DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 SUPERFAMILY SSF52518 371 563 4.57E-61 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 565 1.7E-183 T 31-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 333 1.3E-36 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 Gene3D G3DSA:3.40.50.1220 195 367 3.3E-46 T 31-10-2018 DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 541 3.4E-45 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 SUPERFAMILY SSF52467 157 364 1.72E-43 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 172 5.7E-52 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 431 450 - T 31-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 Gene3D G3DSA:3.40.50.970 368 568 5.8E-60 T 31-10-2018 DFR86_08590 d6b90ffe6c97a522783bb7773423584c 572 SUPERFAMILY SSF52518 2 180 1.39E-57 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 SUPERFAMILY SSF52540 36 282 1.25E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Gene3D G3DSA:3.40.50.140 603 790 7.9E-34 T 31-10-2018 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 SUPERFAMILY SSF52540 302 594 5.9E-31 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 SUPERFAMILY SSF56712 610 1235 7.46E-126 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Hamap MF_01125 Reverse gyrase [rgy]. 5 1237 59.307 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Gene3D G3DSA:3.40.50.300 501 602 1.1E-12 T 31-10-2018 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Gene3D G3DSA:3.40.50.300 296 488 2.6E-25 T 31-10-2018 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Gene3D G3DSA:2.60.510.20 864 1134 1.4E-128 T 31-10-2018 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 SMART SM00493 614 766 4.6E-34 T 31-10-2018 IPR006171 TOPRIM domain DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 740 753 1.3E-23 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1028 1044 1.3E-23 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1150 1164 1.3E-23 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 842 860 1.3E-23 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 944 953 1.3E-23 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Gene3D G3DSA:3.40.50.300 67 295 2.3E-61 T 31-10-2018 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Pfam PF01131 DNA topoisomerase 795 1227 7.2E-70 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 SMART SM00436 767 872 1.6E-33 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 SMART SM00437 902 1189 5.9E-73 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Gene3D G3DSA:1.10.290.10 912 1039 1.4E-128 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Pfam PF01751 Toprim domain 615 776 3.3E-27 T 31-10-2018 IPR006171 TOPRIM domain DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Gene3D G3DSA:1.10.460.10 796 1230 1.4E-128 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 Pfam PF00270 DEAD/DEAH box helicase 90 226 8.7E-10 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 SMART SM00487 82 312 5.0E-22 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_06030 ddbc15170fbc1f698c26ce49150cac9d 1237 TIGRFAM TIGR01054 rgy: reverse gyrase 8 1236 0.0 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 DFR86_10390 2be8bf01bb72bab25637108f20eeb19a 484 Pfam PF09286 Pro-kumamolisin, activation domain 43 160 1.5E-19 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR86_10390 2be8bf01bb72bab25637108f20eeb19a 484 SUPERFAMILY SSF52743 211 476 1.7E-42 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR86_10390 2be8bf01bb72bab25637108f20eeb19a 484 SMART SM00944 40 174 6.5E-29 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR86_10390 2be8bf01bb72bab25637108f20eeb19a 484 Gene3D G3DSA:3.40.50.200 202 481 3.0E-52 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR86_10390 2be8bf01bb72bab25637108f20eeb19a 484 SUPERFAMILY SSF54897 39 184 4.42E-19 T 31-10-2018 DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 SUPERFAMILY SSF81296 2 89 2.0E-14 T 31-10-2018 IPR014756 Immunoglobulin E-set DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 SMART SM00642 110 473 3.6E-10 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 Pfam PF00128 Alpha amylase, catalytic domain 118 207 7.2E-23 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 Pfam PF00128 Alpha amylase, catalytic domain 229 427 2.3E-4 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 PIRSF PIRSF006337 1 522 1.2E-199 T 31-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 13 498 1.3E-196 T 31-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 3 68 5.4E-6 T 31-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 SUPERFAMILY SSF51445 89 491 6.65E-99 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 Gene3D G3DSA:2.60.40.10 1 94 4.0E-19 T 31-10-2018 IPR013783 Immunoglobulin-like fold DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 Gene3D G3DSA:3.20.20.80 103 490 3.2E-153 T 31-10-2018 DFR86_07950 371fca2b02e8c580b4cde0d65afe3a58 558 Gene3D G3DSA:1.10.10.760 433 467 3.2E-153 T 31-10-2018 DFR86_03755 e9b7498a6ecf650df7c2323e9f1a580d 297 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 291 8.5E-15 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 DFR86_03755 e9b7498a6ecf650df7c2323e9f1a580d 297 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 258 3.0E-34 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DFR86_03755 e9b7498a6ecf650df7c2323e9f1a580d 297 SUPERFAMILY SSF52283 1 99 4.68E-22 T 31-10-2018 DFR86_03755 e9b7498a6ecf650df7c2323e9f1a580d 297 Gene3D G3DSA:3.40.50.720 83 259 2.0E-62 T 31-10-2018 DFR86_03755 e9b7498a6ecf650df7c2323e9f1a580d 297 Gene3D G3DSA:3.40.50.720 26 283 2.0E-62 T 31-10-2018 DFR86_03755 e9b7498a6ecf650df7c2323e9f1a580d 297 SUPERFAMILY SSF51735 85 259 2.63E-33 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_09245 de5f8c7874dd1dcf0e3ba5bbc446ec87 153 SMART SM00738 6 91 5.0E-20 T 31-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 DFR86_09245 de5f8c7874dd1dcf0e3ba5bbc446ec87 153 SUPERFAMILY SSF50104 58 151 1.81E-15 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR86_09245 de5f8c7874dd1dcf0e3ba5bbc446ec87 153 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 8 87 2.5E-23 T 31-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 DFR86_09245 de5f8c7874dd1dcf0e3ba5bbc446ec87 153 SMART SM00739 96 123 1.2E-5 T 31-10-2018 IPR005824 KOW DFR86_09245 de5f8c7874dd1dcf0e3ba5bbc446ec87 153 Pfam PF00467 KOW motif 99 127 6.1E-7 T 31-10-2018 IPR005824 KOW DFR86_09245 de5f8c7874dd1dcf0e3ba5bbc446ec87 153 SUPERFAMILY SSF82679 7 76 8.89E-5 T 31-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 DFR86_09245 de5f8c7874dd1dcf0e3ba5bbc446ec87 153 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 10 152 1.5E-36 T 31-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 DFR86_09245 de5f8c7874dd1dcf0e3ba5bbc446ec87 153 Gene3D G3DSA:3.30.70.940 9 94 8.8E-24 T 31-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 DFR86_09245 de5f8c7874dd1dcf0e3ba5bbc446ec87 153 Gene3D G3DSA:2.30.30.30 95 153 9.2E-21 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR86_09245 de5f8c7874dd1dcf0e3ba5bbc446ec87 153 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 8 152 36.504 T 31-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 DFR86_02970 2731e74a9d8b020a59c9ea1c9ad920a2 240 SUPERFAMILY SSF53790 2 238 6.54E-66 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR86_02970 2731e74a9d8b020a59c9ea1c9ad920a2 240 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 209 1.8E-47 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR86_02970 2731e74a9d8b020a59c9ea1c9ad920a2 240 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 31-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR86_02970 2731e74a9d8b020a59c9ea1c9ad920a2 240 Gene3D G3DSA:3.30.950.10 117 240 6.8E-37 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 DFR86_02970 2731e74a9d8b020a59c9ea1c9ad920a2 240 Gene3D G3DSA:3.40.1010.10 1 116 1.2E-38 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR86_02970 2731e74a9d8b020a59c9ea1c9ad920a2 240 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 81 114 - T 31-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR86_02970 2731e74a9d8b020a59c9ea1c9ad920a2 240 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 233 1.7E-88 T 31-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR86_03005 38d9659f31839c00b1752fbb55a204d5 522 Gene3D G3DSA:2.40.30.10 434 520 2.4E-7 T 31-10-2018 DFR86_03005 38d9659f31839c00b1752fbb55a204d5 522 SUPERFAMILY SSF50447 346 467 1.29E-18 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR86_03005 38d9659f31839c00b1752fbb55a204d5 522 Gene3D G3DSA:3.40.50.300 106 335 1.3E-33 T 31-10-2018 DFR86_03005 38d9659f31839c00b1752fbb55a204d5 522 SUPERFAMILY SSF52540 110 358 1.05E-30 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03005 38d9659f31839c00b1752fbb55a204d5 522 Pfam PF03143 Elongation factor Tu C-terminal domain 436 520 1.3E-5 T 31-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal DFR86_03005 38d9659f31839c00b1752fbb55a204d5 522 SUPERFAMILY SSF50465 434 520 3.7E-18 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal DFR86_03005 38d9659f31839c00b1752fbb55a204d5 522 Pfam PF03144 Elongation factor Tu domain 2 358 428 1.4E-9 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 DFR86_03005 38d9659f31839c00b1752fbb55a204d5 522 Pfam PF00009 Elongation factor Tu GTP binding domain 112 328 2.1E-22 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_03005 38d9659f31839c00b1752fbb55a204d5 522 Gene3D G3DSA:2.40.30.10 341 433 4.0E-19 T 31-10-2018 DFR86_04885 d0e76d78753664ab8453fbc4d1b17b19 532 PIRSF PIRSF006060 1 449 5.1E-61 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04885 d0e76d78753664ab8453fbc4d1b17b19 532 PIRSF PIRSF006060 406 523 31.0 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04885 d0e76d78753664ab8453fbc4d1b17b19 532 Gene3D G3DSA:1.20.1740.10 8 457 4.3E-45 T 31-10-2018 DFR86_04885 d0e76d78753664ab8453fbc4d1b17b19 532 Pfam PF13520 Amino acid permease 14 427 4.1E-30 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_11175 c20a22be8bb6e52f4da7aefcc9c7ec4d 459 Gene3D G3DSA:3.30.70.2740 320 401 2.5E-5 T 31-10-2018 DFR86_11175 c20a22be8bb6e52f4da7aefcc9c7ec4d 459 Pfam PF01565 FAD binding domain 36 172 3.0E-29 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_11175 c20a22be8bb6e52f4da7aefcc9c7ec4d 459 SUPERFAMILY SSF55103 208 443 1.14E-57 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DFR86_11175 c20a22be8bb6e52f4da7aefcc9c7ec4d 459 Gene3D G3DSA:1.10.45.10 402 441 3.5E-7 T 31-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 DFR86_11175 c20a22be8bb6e52f4da7aefcc9c7ec4d 459 Gene3D G3DSA:3.30.465.40 2 225 9.8E-44 T 31-10-2018 DFR86_11175 c20a22be8bb6e52f4da7aefcc9c7ec4d 459 SUPERFAMILY SSF56176 3 205 2.1E-47 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_11175 c20a22be8bb6e52f4da7aefcc9c7ec4d 459 Pfam PF02913 FAD linked oxidases, C-terminal domain 204 440 2.3E-52 T 31-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 DFR86_00590 4cfd95fc4a5fad753a0a26c19cdfc3d3 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 249 1.1E-46 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR86_00590 4cfd95fc4a5fad753a0a26c19cdfc3d3 251 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 DFR86_00590 4cfd95fc4a5fad753a0a26c19cdfc3d3 251 Gene3D G3DSA:1.10.12.10 195 250 2.7E-20 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal DFR86_00590 4cfd95fc4a5fad753a0a26c19cdfc3d3 251 SUPERFAMILY SSF52096 2 250 1.51E-61 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR86_00590 4cfd95fc4a5fad753a0a26c19cdfc3d3 251 Gene3D G3DSA:3.90.226.10 1 192 7.3E-45 T 31-10-2018 DFR86_05525 50a3f958e6d2fcb1520f11808e2b7680 410 Pfam PF01979 Amidohydrolase family 53 384 2.6E-49 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_05525 50a3f958e6d2fcb1520f11808e2b7680 410 SUPERFAMILY SSF51338 8 403 5.59E-13 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_05525 50a3f958e6d2fcb1520f11808e2b7680 410 SUPERFAMILY SSF51556 56 338 1.04E-65 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_05525 50a3f958e6d2fcb1520f11808e2b7680 410 Gene3D G3DSA:3.20.20.140 57 339 3.7E-84 T 31-10-2018 DFR86_05525 50a3f958e6d2fcb1520f11808e2b7680 410 Gene3D G3DSA:2.30.40.10 27 386 3.7E-84 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_11800 4b672d59adddb8eb3d5fe69fc9b61c5a 521 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 10 464 6.7E-26 T 31-10-2018 IPR019016 CRISPR-associated DxTHG protein DFR86_11800 4b672d59adddb8eb3d5fe69fc9b61c5a 521 SUPERFAMILY SSF160980 8 470 2.62E-30 T 31-10-2018 DFR86_11800 4b672d59adddb8eb3d5fe69fc9b61c5a 521 Gene3D G3DSA:3.40.50.10640 6 254 2.2E-12 T 31-10-2018 DFR86_00070 4b672d59adddb8eb3d5fe69fc9b61c5a 521 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 10 464 6.7E-26 T 31-10-2018 IPR019016 CRISPR-associated DxTHG protein DFR86_00070 4b672d59adddb8eb3d5fe69fc9b61c5a 521 SUPERFAMILY SSF160980 8 470 2.62E-30 T 31-10-2018 DFR86_00070 4b672d59adddb8eb3d5fe69fc9b61c5a 521 Gene3D G3DSA:3.40.50.10640 6 254 2.2E-12 T 31-10-2018 DFR86_03615 aa554c31a19a5334faaf48614762f008 383 Gene3D G3DSA:3.20.20.80 2 228 5.2E-44 T 31-10-2018 DFR86_03615 aa554c31a19a5334faaf48614762f008 383 Pfam PF00232 Glycosyl hydrolase family 1 227 367 8.6E-24 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR86_03615 aa554c31a19a5334faaf48614762f008 383 Pfam PF00232 Glycosyl hydrolase family 1 49 209 2.4E-29 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR86_03615 aa554c31a19a5334faaf48614762f008 383 Gene3D G3DSA:3.20.20.80 229 382 2.5E-43 T 31-10-2018 DFR86_03615 aa554c31a19a5334faaf48614762f008 383 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 305 313 - T 31-10-2018 IPR018120 Glycoside hydrolase family 1, active site DFR86_03615 aa554c31a19a5334faaf48614762f008 383 PRINTS PR00131 Glycosyl hydrolase family 1 signature 240 254 1.1E-11 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR86_03615 aa554c31a19a5334faaf48614762f008 383 PRINTS PR00131 Glycosyl hydrolase family 1 signature 335 352 1.1E-11 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR86_03615 aa554c31a19a5334faaf48614762f008 383 PRINTS PR00131 Glycosyl hydrolase family 1 signature 359 371 1.1E-11 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR86_03615 aa554c31a19a5334faaf48614762f008 383 PRINTS PR00131 Glycosyl hydrolase family 1 signature 305 313 1.1E-11 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR86_03615 aa554c31a19a5334faaf48614762f008 383 SUPERFAMILY SSF51445 4 379 5.8E-89 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 Pfam PF14551 MCM N-terminal domain 9 98 3.2E-16 T 31-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 Gene3D G3DSA:3.30.1640.10 2 102 2.4E-24 T 31-10-2018 DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 SMART SM00350 102 596 5.2E-208 T 31-10-2018 IPR031327 Mini-chromosome maintenance protein DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 Gene3D G3DSA:3.40.50.300 272 600 1.0E-135 T 31-10-2018 DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 Pfam PF17207 MCM OB domain 106 237 2.4E-36 T 31-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 Gene3D G3DSA:1.10.10.10 601 684 6.7E-28 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 SUPERFAMILY SSF50249 11 256 2.74E-64 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 Gene3D G3DSA:2.20.28.10 137 183 7.2E-27 T 31-10-2018 DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 SUPERFAMILY SSF52540 299 593 7.92E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 417 430 4.6E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 329 344 4.6E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 441 453 4.6E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 389 403 4.6E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 468 476 4.6E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR86_05350 480a0a1777ff1bad4c85b1f972db8562 684 Pfam PF00493 MCM2/3/5 family 276 592 2.7E-134 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 Pfam PF00117 Glutamine amidotransferase class-I 7 184 3.9E-38 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 187 2.1E-61 T 31-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 PRINTS PR00097 Anthranilate synthase component II signature 45 54 1.4E-7 T 31-10-2018 DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.4E-7 T 31-10-2018 DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 PRINTS PR00097 Anthranilate synthase component II signature 162 175 1.4E-7 T 31-10-2018 DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 SUPERFAMILY SSF52317 2 187 2.46E-52 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 2 188 39.938 T 31-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 Gene3D G3DSA:3.40.50.880 1 188 1.8E-58 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 45 54 1.1E-8 T 31-10-2018 DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 162 175 1.1E-8 T 31-10-2018 DFR86_01710 aaa25c23eb396e2ce39e654b3692e193 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.1E-8 T 31-10-2018 DFR86_06540 b84fcfd429e43adf176f45b2d3793848 238 SUPERFAMILY SSF159659 5 228 8.11E-33 T 31-10-2018 DFR86_06540 b84fcfd429e43adf176f45b2d3793848 238 Gene3D G3DSA:3.40.50.10900 1 237 4.0E-43 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily DFR86_06540 b84fcfd429e43adf176f45b2d3793848 238 Pfam PF09754 PAC2 family 18 220 4.1E-32 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 DFR86_01950 782b4d7fa6cb707b47706673fde502fa 200 Pfam PF08241 Methyltransferase domain 36 117 8.9E-15 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR86_01950 782b4d7fa6cb707b47706673fde502fa 200 Gene3D G3DSA:3.40.50.150 21 184 7.1E-30 T 31-10-2018 DFR86_01950 782b4d7fa6cb707b47706673fde502fa 200 SUPERFAMILY SSF53335 28 180 1.98E-26 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_05765 894e6259664b2d640d9d6f92d45ee7d7 66 PIRSF PIRSF005653 1 66 2.2E-30 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_05765 894e6259664b2d640d9d6f92d45ee7d7 66 SUPERFAMILY SSF46924 1 63 8.11E-27 T 31-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_05765 894e6259664b2d640d9d6f92d45ee7d7 66 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 31-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_05765 894e6259664b2d640d9d6f92d45ee7d7 66 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 22.233 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_05765 894e6259664b2d640d9d6f92d45ee7d7 66 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 1.0E-14 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_05765 894e6259664b2d640d9d6f92d45ee7d7 66 Gene3D G3DSA:1.10.10.60 1 66 3.4E-32 T 31-10-2018 DFR86_05765 894e6259664b2d640d9d6f92d45ee7d7 66 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 58 4.5E-29 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_06380 027f269ec4e3625de911654bce1f9047 335 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 64 335 2.0E-86 T 31-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 DFR86_06380 027f269ec4e3625de911654bce1f9047 335 Pfam PF01189 16S rRNA methyltransferase RsmB/F 130 333 3.0E-53 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 DFR86_06380 027f269ec4e3625de911654bce1f9047 335 SUPERFAMILY SSF53335 24 335 4.53E-70 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_06380 027f269ec4e3625de911654bce1f9047 335 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 207 218 - T 31-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 DFR86_06380 027f269ec4e3625de911654bce1f9047 335 Gene3D G3DSA:3.40.50.150 129 335 1.8E-66 T 31-10-2018 DFR86_06380 027f269ec4e3625de911654bce1f9047 335 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 38 127 5.0E-16 T 31-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 DFR86_06380 027f269ec4e3625de911654bce1f9047 335 Gene3D G3DSA:3.30.70.3130 17 126 2.0E-31 T 31-10-2018 DFR86_06380 027f269ec4e3625de911654bce1f9047 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 258 274 1.2E-28 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_06380 027f269ec4e3625de911654bce1f9047 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 142 152 1.2E-28 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_06380 027f269ec4e3625de911654bce1f9047 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 208 220 1.2E-28 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_06380 027f269ec4e3625de911654bce1f9047 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 318 335 1.2E-28 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_06380 027f269ec4e3625de911654bce1f9047 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 113 127 1.2E-28 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 SUPERFAMILY SSF52540 183 384 2.17E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 358 371 - T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 112 384 4.2E-108 T 31-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 SUPERFAMILY SSF47364 101 174 9.27E-12 T 31-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 SMART SM00382 189 336 4.0E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 SMART SM00962 190 385 8.0E-104 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 SMART SM00963 88 171 1.7E-8 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 Gene3D G3DSA:3.40.50.300 178 385 1.6E-77 T 31-10-2018 DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 Pfam PF02881 SRP54-type protein, helical bundle domain 100 163 5.9E-12 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 Gene3D G3DSA:1.20.120.140 66 174 3.4E-22 T 31-10-2018 DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 110 385 58.179 T 31-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 DFR86_09235 4a583aabb0a4f6b7cf285159960d3147 385 Pfam PF00448 SRP54-type protein, GTPase domain 190 384 1.8E-72 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR86_03190 b5c35556efe5e13e49d695d484772e23 579 Gene3D G3DSA:3.40.50.300 287 571 5.8E-76 T 31-10-2018 DFR86_03190 b5c35556efe5e13e49d695d484772e23 579 SUPERFAMILY SSF52540 164 479 2.79E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03190 b5c35556efe5e13e49d695d484772e23 579 Gene3D G3DSA:3.30.450.380 48 285 9.0E-48 T 31-10-2018 DFR86_03190 b5c35556efe5e13e49d695d484772e23 579 Pfam PF00437 Type II/IV secretion system protein 222 436 4.7E-43 T 31-10-2018 IPR001482 Type II/IV secretion system protein DFR86_06970 656efda1d73c077f76985f0448c32866 410 SUPERFAMILY SSF52507 18 216 2.62E-41 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 DFR86_06970 656efda1d73c077f76985f0448c32866 410 Pfam PF02441 Flavoprotein 19 180 8.5E-33 T 31-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 DFR86_06970 656efda1d73c077f76985f0448c32866 410 Gene3D G3DSA:3.40.50.1950 13 192 3.6E-42 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 DFR86_06970 656efda1d73c077f76985f0448c32866 410 Gene3D G3DSA:3.40.50.10300 193 409 3.3E-60 T 31-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 DFR86_06970 656efda1d73c077f76985f0448c32866 410 SUPERFAMILY SSF102645 190 403 2.88E-61 T 31-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 DFR86_06970 656efda1d73c077f76985f0448c32866 410 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 16 401 3.5E-91 T 31-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 DFR86_06970 656efda1d73c077f76985f0448c32866 410 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 192 377 1.6E-54 T 31-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 DFR86_06530 d3f0ff8c9025f0bc230003522cbf5f43 145 Gene3D G3DSA:2.30.30.100 8 73 9.1E-14 T 31-10-2018 DFR86_06530 d3f0ff8c9025f0bc230003522cbf5f43 145 SUPERFAMILY SSF50182 11 136 4.03E-16 T 31-10-2018 IPR010920 LSM domain superfamily DFR86_06530 d3f0ff8c9025f0bc230003522cbf5f43 145 SMART SM00651 9 71 0.0057 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type DFR86_06530 d3f0ff8c9025f0bc230003522cbf5f43 145 Pfam PF01423 LSM domain 11 66 1.8E-7 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type DFR86_06530 d3f0ff8c9025f0bc230003522cbf5f43 145 Pfam PF14894 Lsm C-terminal 79 141 4.9E-29 T 31-10-2018 IPR028277 Lsm, C-terminal DFR86_06530 d3f0ff8c9025f0bc230003522cbf5f43 145 Gene3D G3DSA:3.30.310.60 78 137 8.3E-18 T 31-10-2018 IPR037156 Like-Sm ribonucleoprotein, C-terminal domain superfamily DFR86_07185 c2f3f75a30b7e2b65701643d99a5f509 56 Gene3D G3DSA:2.20.28.70 1 56 1.0E-27 T 31-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR86_07185 c2f3f75a30b7e2b65701643d99a5f509 56 Pfam PF01020 Ribosomal L40e family 17 49 3.2E-7 T 31-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR86_07185 c2f3f75a30b7e2b65701643d99a5f509 56 SUPERFAMILY SSF57829 1 55 3.3E-18 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR86_07185 c2f3f75a30b7e2b65701643d99a5f509 56 SMART SM01377 3 51 3.2E-19 T 31-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR86_07185 c2f3f75a30b7e2b65701643d99a5f509 56 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 7 52 16.677 T 31-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 DFR86_04275 481efab423ca4ad7a54c62b4c26b1e3c 376 SUPERFAMILY SSF55909 5 375 4.32E-77 T 31-10-2018 DFR86_04275 481efab423ca4ad7a54c62b4c26b1e3c 376 PRINTS PR01466 Bacterial arginine deiminase signature 331 345 1.0E-8 T 31-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 DFR86_04275 481efab423ca4ad7a54c62b4c26b1e3c 376 PRINTS PR01466 Bacterial arginine deiminase signature 132 150 1.0E-8 T 31-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 DFR86_04275 481efab423ca4ad7a54c62b4c26b1e3c 376 PRINTS PR01466 Bacterial arginine deiminase signature 311 328 1.0E-8 T 31-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 DFR86_04275 481efab423ca4ad7a54c62b4c26b1e3c 376 Pfam PF02274 Amidinotransferase 17 374 1.4E-50 T 31-10-2018 DFR86_04275 481efab423ca4ad7a54c62b4c26b1e3c 376 Gene3D G3DSA:1.10.3930.10 66 132 3.2E-76 T 31-10-2018 DFR86_04275 481efab423ca4ad7a54c62b4c26b1e3c 376 Gene3D G3DSA:3.75.10.10 5 374 3.2E-76 T 31-10-2018 DFR86_04665 df4de96851fd81ce1e84a76e2fc79411 288 SUPERFAMILY SSF56529 50 286 6.54E-35 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR86_04665 df4de96851fd81ce1e84a76e2fc79411 288 Gene3D G3DSA:3.90.850.10 51 288 7.2E-35 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR86_04665 df4de96851fd81ce1e84a76e2fc79411 288 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 56 283 3.0E-36 T 31-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 Gene3D G3DSA:1.20.120.140 6 304 7.5E-110 T 31-10-2018 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 SMART SM00963 2 83 2.7E-17 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 SUPERFAMILY SSF47364 4 89 4.01E-18 T 31-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 Gene3D G3DSA:1.10.260.30 305 432 1.3E-41 T 31-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 SMART SM00962 97 294 6.0E-97 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 SMART SM00382 96 299 2.0E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 2 442 35.571 T 31-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 SUPERFAMILY SSF47446 296 431 2.22E-40 T 31-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 SUPERFAMILY SSF52540 97 296 1.23E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 Gene3D G3DSA:3.40.50.300 87 283 7.5E-110 T 31-10-2018 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 Pfam PF00448 SRP54-type protein, GTPase domain 98 294 6.0E-72 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 Pfam PF02978 Signal peptide binding domain 328 427 1.8E-27 T 31-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 DFR86_09885 c27194df5ff84e565597c54f613a93b7 450 Pfam PF02881 SRP54-type protein, helical bundle domain 5 79 1.4E-14 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR86_01165 1d2f1fa41988fec94c57b5db03e094da 424 PIRSF PIRSF006060 1 404 9.4E-68 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_01165 1d2f1fa41988fec94c57b5db03e094da 424 Gene3D G3DSA:1.20.1740.10 1 418 8.9E-86 T 31-10-2018 DFR86_01165 1d2f1fa41988fec94c57b5db03e094da 424 Pfam PF13520 Amino acid permease 6 381 1.5E-41 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 SUPERFAMILY SSF55681 146 486 1.29E-107 T 31-10-2018 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 Pfam PF00152 tRNA synthetases class II (D, K and N) 147 486 5.5E-83 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 6 490 37.861 T 31-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 199 215 1.5E-32 T 31-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 246 263 1.5E-32 T 31-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 372 388 1.5E-32 T 31-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 228 241 1.5E-32 T 31-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 PRINTS PR00982 Lysyl-tRNA synthetase signature 183 193 1.5E-32 T 31-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 6 488 5.1E-161 T 31-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 Gene3D G3DSA:2.40.50.140 2 142 2.3E-37 T 31-10-2018 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 SUPERFAMILY SSF50249 5 141 2.42E-32 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 Pfam PF01336 OB-fold nucleic acid binding domain 57 132 5.8E-11 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 DFR86_05865 c9765db7bd459e639b28d42b9ba0eb44 495 Gene3D G3DSA:3.30.930.10 156 489 2.0E-120 T 31-10-2018 DFR86_06595 aecde0e09c686420167ee3eb47c02f43 304 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 7 288 34.727 T 31-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 DFR86_06595 aecde0e09c686420167ee3eb47c02f43 304 SUPERFAMILY SSF53335 4 288 1.51E-77 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_06595 aecde0e09c686420167ee3eb47c02f43 304 Gene3D G3DSA:2.30.140.10 6 56 1.0E-11 T 31-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 DFR86_06595 aecde0e09c686420167ee3eb47c02f43 304 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 83 96 - T 31-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 DFR86_06595 aecde0e09c686420167ee3eb47c02f43 304 Pfam PF01564 Spermine/spermidine synthase domain 62 242 7.6E-47 T 31-10-2018 DFR86_06595 aecde0e09c686420167ee3eb47c02f43 304 Gene3D G3DSA:3.40.50.150 58 303 3.2E-79 T 31-10-2018 DFR86_06595 aecde0e09c686420167ee3eb47c02f43 304 Pfam PF17284 Spermidine synthase tetramerisation domain 8 58 1.8E-7 T 31-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 DFR86_11225 39aecf0a3561425ded981977e5f00339 347 PIRSF PIRSF037420 2 347 1.1E-79 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR86_11225 39aecf0a3561425ded981977e5f00339 347 Gene3D G3DSA:3.20.20.70 2 311 7.5E-39 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_11225 39aecf0a3561425ded981977e5f00339 347 Pfam PF04055 Radical SAM superfamily 13 154 1.2E-13 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_11225 39aecf0a3561425ded981977e5f00339 347 Pfam PF13353 4Fe-4S single cluster domain 15 83 9.3E-6 T 31-10-2018 DFR86_11225 39aecf0a3561425ded981977e5f00339 347 SMART SM00729 8 208 0.0069 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_11225 39aecf0a3561425ded981977e5f00339 347 SUPERFAMILY SSF102114 3 326 2.49E-56 T 31-10-2018 DFR86_11225 39aecf0a3561425ded981977e5f00339 347 Pfam PF13186 Iron-sulfur cluster-binding domain 264 318 5.2E-6 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR86_11225 39aecf0a3561425ded981977e5f00339 347 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 2 347 9.3E-134 T 31-10-2018 IPR027634 Radical SAM protein, BA_1875 family DFR86_02350 d88efc9fd6e518d8e034d80e315f6b1e 118 Gene3D G3DSA:1.10.10.10 1 107 3.0E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_02350 d88efc9fd6e518d8e034d80e315f6b1e 118 SUPERFAMILY SSF46785 2 82 2.06E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_02350 d88efc9fd6e518d8e034d80e315f6b1e 118 Pfam PF03551 Transcriptional regulator PadR-like family 16 78 1.2E-12 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal DFR86_00020 d13aa4c5a70f603992c5798572e6ca70 752 SUPERFAMILY SSF49899 359 515 6.07E-10 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily DFR86_00020 d13aa4c5a70f603992c5798572e6ca70 752 Gene3D G3DSA:2.60.120.200 311 541 9.6E-13 T 31-10-2018 DFR86_11750 d13aa4c5a70f603992c5798572e6ca70 752 SUPERFAMILY SSF49899 359 515 6.07E-10 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily DFR86_11750 d13aa4c5a70f603992c5798572e6ca70 752 Gene3D G3DSA:2.60.120.200 311 541 9.6E-13 T 31-10-2018 DFR86_04005 302a1f6aabe19b3b4e68efdc95106145 395 Gene3D G3DSA:1.10.10.2140 333 383 2.7E-21 T 31-10-2018 DFR86_04005 302a1f6aabe19b3b4e68efdc95106145 395 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 18 383 3.1E-107 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 DFR86_04005 302a1f6aabe19b3b4e68efdc95106145 395 Gene3D G3DSA:3.40.50.11750 39 277 6.1E-93 T 31-10-2018 DFR86_04005 302a1f6aabe19b3b4e68efdc95106145 395 Gene3D G3DSA:3.40.50.11740 72 317 6.1E-93 T 31-10-2018 DFR86_04005 302a1f6aabe19b3b4e68efdc95106145 395 Pfam PF01924 Hydrogenase formation hypA family 21 380 8.4E-118 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 DFR86_04005 302a1f6aabe19b3b4e68efdc95106145 395 PIRSF PIRSF005622 9 386 6.6E-128 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 Gene3D G3DSA:3.10.20.30 298 378 6.2E-26 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 SUPERFAMILY SSF47741 377 450 2.49E-19 T 31-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 Gene3D G3DSA:3.30.43.10 10 59 8.5E-15 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 Gene3D G3DSA:3.30.465.10 64 169 6.6E-34 T 31-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 SUPERFAMILY SSF54292 300 383 1.44E-19 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 Gene3D G3DSA:1.10.150.120 379 453 1.7E-18 T 31-10-2018 DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 343 351 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 312 358 3.6E-7 T 31-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 SUPERFAMILY SSF56176 10 170 1.31E-43 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 13 169 1.7E-43 T 31-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DFR86_00550 e8a1f714119df36eedf95c212b1b2ffe 453 Pfam PF01799 [2Fe-2S] binding domain 377 449 6.4E-19 T 31-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 Gene3D G3DSA:3.40.50.20 3 97 5.6E-17 T 31-10-2018 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 3 104 3.3E-18 T 31-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 Gene3D G3DSA:3.30.1490.20 124 199 1.4E-9 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 SUPERFAMILY SSF56059 106 332 5.48E-33 T 31-10-2018 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 Gene3D G3DSA:3.90.600.10 345 440 5.9E-11 T 31-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 SUPERFAMILY SSF52440 3 104 1.73E-18 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 Gene3D G3DSA:3.30.470.20 200 342 1.4E-35 T 31-10-2018 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 SUPERFAMILY SSF51246 345 439 3.37E-12 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 347 438 1.7E-9 T 31-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 106 309 4.4E-39 T 31-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 3 439 8.6E-96 T 31-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 SMART SM01209 105 309 1.4E-67 T 31-10-2018 DFR86_08320 614a29cc9c73b80b6ddd1b0698cbf8cb 476 SMART SM01210 344 441 4.9E-9 T 31-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR86_00820 79e6d894fd6c3a9b39eca5081ad8cbb4 349 Gene3D G3DSA:1.10.8.60 198 271 3.0E-20 T 31-10-2018 DFR86_00820 79e6d894fd6c3a9b39eca5081ad8cbb4 349 Pfam PF01637 ATPase domain predominantly from Archaea 14 237 7.4E-22 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR86_00820 79e6d894fd6c3a9b39eca5081ad8cbb4 349 SUPERFAMILY SSF52540 3 271 9.73E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00820 79e6d894fd6c3a9b39eca5081ad8cbb4 349 Gene3D G3DSA:1.10.10.10 280 345 4.0E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_00820 79e6d894fd6c3a9b39eca5081ad8cbb4 349 SUPERFAMILY SSF46785 280 344 1.85E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_00820 79e6d894fd6c3a9b39eca5081ad8cbb4 349 Gene3D G3DSA:3.40.50.300 1 196 1.9E-48 T 31-10-2018 DFR86_07165 f1cad12bef054f5617e782bd49f9f80e 119 SUPERFAMILY SSF102462 1 119 1.24E-40 T 31-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 DFR86_07165 f1cad12bef054f5617e782bd49f9f80e 119 Gene3D G3DSA:3.40.1490.10 1 119 4.2E-48 T 31-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 DFR86_07165 f1cad12bef054f5617e782bd49f9f80e 119 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 1 119 1.9E-41 T 31-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 DFR86_07165 f1cad12bef054f5617e782bd49f9f80e 119 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 1 119 3.4E-41 T 31-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 DFR86_07165 f1cad12bef054f5617e782bd49f9f80e 119 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 1 119 29.029 T 31-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 DFR86_09125 ff976938a3b80349a5877db3f57e2bd0 132 Pfam PF00085 Thioredoxin 31 129 7.8E-25 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 DFR86_09125 ff976938a3b80349a5877db3f57e2bd0 132 TIGRFAM TIGR01068 thioredoxin: thioredoxin 34 130 1.5E-30 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DFR86_09125 ff976938a3b80349a5877db3f57e2bd0 132 Gene3D G3DSA:3.40.30.10 12 131 1.7E-32 T 31-10-2018 DFR86_09125 ff976938a3b80349a5877db3f57e2bd0 132 ProSitePatterns PS00194 Thioredoxin family active site. 49 67 - T 31-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 DFR86_09125 ff976938a3b80349a5877db3f57e2bd0 132 SUPERFAMILY SSF52833 22 132 3.5E-34 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_09125 ff976938a3b80349a5877db3f57e2bd0 132 PIRSF PIRSF000077 27 132 5.3E-31 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 17 316 6.3E-106 T 31-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 Gene3D G3DSA:3.50.50.60 126 248 4.0E-118 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 305 1.3E-50 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 Gene3D G3DSA:3.50.50.60 16 312 4.0E-118 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 18 37 1.3E-32 T 31-10-2018 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.3E-32 T 31-10-2018 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 1.3E-32 T 31-10-2018 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 1.3E-32 T 31-10-2018 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 1.3E-32 T 31-10-2018 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 115 123 4.9E-52 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 263 4.9E-52 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 17 39 4.9E-52 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 137 149 4.9E-52 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 4.9E-52 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 49 64 4.9E-52 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 297 316 4.9E-52 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 204 220 4.9E-52 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 SUPERFAMILY SSF51905 9 316 7.33E-47 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03055 a4e84e6985060ae5c83b7d2ca9072c84 323 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 144 164 - T 31-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 DFR86_01130 c4041e5e088fc756a3c00464bb2d495e 347 Pfam PF13240 zinc-ribbon domain 4 25 4.7E-8 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 TIGRFAM TIGR01647 ATPase-IIIA_H: plasma-membrane proton-efflux P-type ATPase 23 753 8.9E-242 T 31-10-2018 IPR006534 P-type ATPase, subfamily IIIA GO:0008553|GO:0016021|GO:0120029 KEGG: 00190+3.6.3.6 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 SUPERFAMILY SSF81660 348 446 1.5E-8 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 Pfam PF00702 haloacid dehalogenase-like hydrolase 307 561 1.2E-19 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 SUPERFAMILY SSF81665 5 790 1.96E-76 T 31-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 Pfam PF00122 E1-E2 ATPase 114 289 4.6E-52 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 579 604 7.0E-28 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 548 564 7.0E-28 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 520 536 7.0E-28 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 418 436 7.0E-28 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 Gene3D G3DSA:3.40.50.1000 450 508 1.9E-6 T 31-10-2018 IPR023214 HAD superfamily DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 160 174 9.4E-33 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 548 567 9.4E-33 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 571 583 9.4E-33 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 309 323 9.4E-33 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 470 480 9.4E-33 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 448 459 9.4E-33 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 SMART SM00831 4 76 4.2E-19 T 31-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 SUPERFAMILY SSF81653 114 210 1.44E-29 T 31-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 SUPERFAMILY SSF56784 310 641 4.34E-40 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 Gene3D G3DSA:1.20.1110.10 509 789 3.3E-49 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 518 628 3.3E-30 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 494 5.7E-64 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 Gene3D G3DSA:1.20.1110.10 201 323 6.6E-15 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 Pfam PF00690 Cation transporter/ATPase, N-terminus 7 70 2.0E-15 T 31-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 Gene3D G3DSA:2.60.120.1500 112 200 7.0E-33 T 31-10-2018 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 Gene3D G3DSA:3.40.1110.10 326 449 1.7E-26 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 DFR86_03425 ae7eeae7c83ac76c4af028b004fe1a6e 794 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 311 317 - T 31-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 SUPERFAMILY SSF55681 113 424 9.43E-88 T 31-10-2018 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 Pfam PF00152 tRNA synthetases class II (D, K and N) 115 423 2.1E-89 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 344 360 2.8E-19 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 384 398 2.8E-19 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 184 196 2.8E-19 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 200 213 2.8E-19 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 6 429 1.9E-148 T 31-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 Gene3D G3DSA:2.40.50.140 1 102 2.3E-28 T 31-10-2018 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 Gene3D G3DSA:3.30.930.10 103 429 4.3E-113 T 31-10-2018 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 Pfam PF01336 OB-fold nucleic acid binding domain 19 95 6.3E-14 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 429 40.254 T 31-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_07175 669571350f19fe4e4ecdf90b92cb0a4b 429 SUPERFAMILY SSF50249 2 102 3.62E-27 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_09180 2d35f28a6c1e3e8ce223186e190374d3 133 Gene3D G3DSA:3.40.1260.10 1 132 1.8E-19 T 31-10-2018 IPR027396 DsrEFH-like DFR86_09180 2d35f28a6c1e3e8ce223186e190374d3 133 SUPERFAMILY SSF75169 1 132 1.11E-17 T 31-10-2018 IPR027396 DsrEFH-like DFR86_09180 2d35f28a6c1e3e8ce223186e190374d3 133 Pfam PF13686 DsrE/DsrF/DrsH-like family 48 129 1.5E-8 T 31-10-2018 IPR032836 DsrE2-like family DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 SUPERFAMILY SSF52540 339 588 1.5E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 Gene3D G3DSA:3.40.50.300 336 510 6.2E-59 T 31-10-2018 DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 SMART SM00382 92 229 1.4E-23 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 SMART SM00382 376 512 3.3E-19 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 96 226 1.5E-39 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 380 509 4.1E-40 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 Gene3D G3DSA:1.10.8.60 511 604 5.2E-18 T 31-10-2018 DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 Gene3D G3DSA:3.40.50.300 44 228 3.0E-64 T 31-10-2018 DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 ProSitePatterns PS00674 AAA-protein family signature. 480 498 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 SUPERFAMILY SSF52540 54 316 1.08E-71 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03045 0fa2b3dd6d8c499b39f55270b7b33ab7 605 Gene3D G3DSA:1.10.8.60 229 324 1.4E-25 T 31-10-2018 DFR86_07495 4da169942117e33c86a5f3cfce0faaf9 382 SMART SM00327 37 202 8.8E-20 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR86_07495 4da169942117e33c86a5f3cfce0faaf9 382 Gene3D G3DSA:3.40.50.410 39 205 1.1E-32 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR86_07495 4da169942117e33c86a5f3cfce0faaf9 382 SUPERFAMILY SSF53300 38 197 3.01E-29 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR86_07495 4da169942117e33c86a5f3cfce0faaf9 382 Pfam PF00092 von Willebrand factor type A domain 41 193 2.1E-18 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR86_07170 36d7bd929ed59b51507897cd65ae1d17 368 Gene3D G3DSA:1.10.1510.30 169 254 6.7E-17 T 31-10-2018 DFR86_07170 36d7bd929ed59b51507897cd65ae1d17 368 SUPERFAMILY SSF55120 27 362 5.9E-47 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 DFR86_07170 36d7bd929ed59b51507897cd65ae1d17 368 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 10 283 2.5E-52 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 DFR86_07170 36d7bd929ed59b51507897cd65ae1d17 368 Gene3D G3DSA:3.30.70.3160 46 128 3.2E-8 T 31-10-2018 DFR86_07170 36d7bd929ed59b51507897cd65ae1d17 368 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 85 98 - T 31-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 DFR86_00090 d5b9e7d0960134346ceab654b4fa17f5 895 Gene3D G3DSA:3.40.50.300 303 527 5.0E-34 T 31-10-2018 DFR86_00090 d5b9e7d0960134346ceab654b4fa17f5 895 Gene3D G3DSA:3.40.50.10810 32 287 3.2E-45 T 31-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily DFR86_00090 d5b9e7d0960134346ceab654b4fa17f5 895 Pfam PF00271 Helicase conserved C-terminal domain 378 497 6.9E-16 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_00090 d5b9e7d0960134346ceab654b4fa17f5 895 SMART SM00490 410 498 9.7E-15 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_00090 d5b9e7d0960134346ceab654b4fa17f5 895 SMART SM00487 30 219 7.8E-20 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_00090 d5b9e7d0960134346ceab654b4fa17f5 895 Pfam PF00176 SNF2 family N-terminal domain 54 201 3.5E-14 T 31-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 DFR86_00090 d5b9e7d0960134346ceab654b4fa17f5 895 SUPERFAMILY SSF52540 81 516 6.24E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08300 763ababb99583d9f837f9e02ce639fbb 391 Gene3D G3DSA:3.40.50.620 1 169 4.3E-61 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_08300 763ababb99583d9f837f9e02ce639fbb 391 Gene3D G3DSA:3.90.1260.10 170 391 6.9E-72 T 31-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR86_08300 763ababb99583d9f837f9e02ce639fbb 391 SUPERFAMILY SSF52402 1 200 2.87E-44 T 31-10-2018 DFR86_08300 763ababb99583d9f837f9e02ce639fbb 391 SUPERFAMILY SSF69864 168 389 8.37E-75 T 31-10-2018 DFR86_08300 763ababb99583d9f837f9e02ce639fbb 391 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 390 45.116 T 31-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR86_08300 763ababb99583d9f837f9e02ce639fbb 391 Pfam PF00764 Arginosuccinate synthase 4 382 1.2E-145 T 31-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR86_08300 763ababb99583d9f837f9e02ce639fbb 391 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 114 125 - T 31-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR86_08300 763ababb99583d9f837f9e02ce639fbb 391 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 6 14 - T 31-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR86_08300 763ababb99583d9f837f9e02ce639fbb 391 TIGRFAM TIGR00032 argG: argininosuccinate synthase 2 385 3.7E-136 T 31-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR86_02325 c4ffa52778fb9f54dd820da19f1b0d0b 1011 Gene3D G3DSA:3.40.50.200 159 511 4.8E-71 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR86_02325 c4ffa52778fb9f54dd820da19f1b0d0b 1011 SUPERFAMILY SSF52743 171 506 1.06E-59 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR86_02325 c4ffa52778fb9f54dd820da19f1b0d0b 1011 SUPERFAMILY SSF54897 20 128 9.86E-5 T 31-10-2018 DFR86_02325 c4ffa52778fb9f54dd820da19f1b0d0b 1011 SMART SM00944 19 143 9.4E-8 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR86_02325 c4ffa52778fb9f54dd820da19f1b0d0b 1011 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 433 443 - T 31-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site DFR86_08970 a969463fac8dca0688dedec943d8a9ed 65 Pfam PF01667 Ribosomal protein S27 11 61 4.9E-22 T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_08970 a969463fac8dca0688dedec943d8a9ed 65 SUPERFAMILY SSF57829 11 62 8.61E-20 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR86_08970 a969463fac8dca0688dedec943d8a9ed 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 21.706 T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_08970 a969463fac8dca0688dedec943d8a9ed 65 Gene3D G3DSA:2.20.25.100 12 65 2.3E-23 T 31-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily DFR86_02895 bac091e4304aaede13ff380954da9a11 478 Pfam PF02910 Fumarate reductase flavoprotein C-term 432 473 2.9E-10 T 31-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 Gene3D G3DSA:1.20.58.100 374 477 6.9E-29 T 31-10-2018 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 SUPERFAMILY SSF46977 393 475 1.44E-23 T 31-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 PIRSF PIRSF000171 1 432 2.2E-27 T 31-10-2018 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 PIRSF PIRSF000171 385 478 3.5E-5 T 31-10-2018 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 SUPERFAMILY SSF56425 205 313 8.22E-29 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 3.6E-11 T 31-10-2018 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 316 338 3.6E-11 T 31-10-2018 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 2 21 3.6E-11 T 31-10-2018 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 Gene3D G3DSA:3.90.700.10 213 308 2.0E-144 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 Gene3D G3DSA:3.50.50.60 4 360 2.0E-144 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_02895 bac091e4304aaede13ff380954da9a11 478 Pfam PF00890 FAD binding domain 4 353 3.9E-75 T 31-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_02895 bac091e4304aaede13ff380954da9a11 478 SUPERFAMILY SSF51905 4 364 4.45E-56 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_02895 bac091e4304aaede13ff380954da9a11 478 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 2 461 8.1E-138 T 31-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 Pfam PF10996 Beta-Casp domain 417 538 5.2E-24 T 31-10-2018 IPR022712 Beta-Casp domain DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 Gene3D G3DSA:3.30.300.230 11 168 1.7E-58 T 31-10-2018 DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 SUPERFAMILY SSF56281 177 636 2.3E-131 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 Pfam PF17214 KH domain 6 68 2.2E-22 T 31-10-2018 IPR033769 KH domain, archaeal DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 Pfam PF16661 Metallo-beta-lactamase superfamily domain 196 362 6.3E-13 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 Gene3D G3DSA:3.40.50.10890 385 570 4.3E-148 T 31-10-2018 DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 Gene3D G3DSA:3.30.300.20 64 134 1.7E-58 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 6 637 2.5E-282 T 31-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 558 618 3.9E-14 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 Gene3D G3DSA:3.60.15.10 183 608 4.3E-148 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 SMART SM01027 417 539 1.6E-48 T 31-10-2018 IPR022712 Beta-Casp domain DFR86_07225 b4cc8aa34ea7492c741e0a8d08a32f53 638 SMART SM00849 190 397 6.1E-28 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 SUPERFAMILY SSF53613 210 484 7.79E-68 T 31-10-2018 IPR029056 Ribokinase-like DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 Gene3D G3DSA:3.40.50.10260 2 206 8.7E-55 T 31-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 Gene3D G3DSA:3.40.1190.20 213 496 4.9E-80 T 31-10-2018 IPR029056 Ribokinase-like DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 210 488 23.271 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 2 202 2.8E-54 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 Pfam PF01256 Carbohydrate kinase 233 480 5.1E-53 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 SUPERFAMILY SSF64153 2 231 2.22E-55 T 31-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 216 484 1.1E-75 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 PIRSF PIRSF017184 1 489 1.6E-104 T 31-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 424 434 - T 31-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 2 202 22.366 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DFR86_02450 65b7d5f5c4599fe9da02e3c8337eb446 501 Pfam PF03853 YjeF-related protein N-terminus 24 187 3.1E-42 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 294 2.4E-103 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 126 137 1.1E-18 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 249 258 1.1E-18 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 42 61 1.1E-18 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 259 282 1.1E-18 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 125 142 1.6E-29 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 214 223 1.6E-29 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 253 258 1.6E-29 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 1.6E-29 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 275 289 1.6E-29 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 PRINTS PR00101 Aspartate carbamoyltransferase signature 32 54 1.6E-29 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 292 8.2E-26 T 31-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 SUPERFAMILY SSF53671 2 295 1.97E-84 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 42 49 - T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 138 6.0E-39 T 31-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 Gene3D G3DSA:3.40.50.1370 127 274 5.7E-105 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 296 34.639 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08415 421115a43820f153e98731bf9e4cf744 296 Gene3D G3DSA:3.40.50.1370 3 290 5.7E-105 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR86_05620 2de5479651ef170e2b44a7cd8d483dc1 116 Gene3D G3DSA:3.40.140.10 2 108 9.2E-9 T 31-10-2018 DFR86_05620 2de5479651ef170e2b44a7cd8d483dc1 116 SUPERFAMILY SSF102712 3 87 7.19E-10 T 31-10-2018 DFR86_11535 14b91417a2861fff10a8a6cd14fbe2be 281 TIGRFAM TIGR01896 cas_AF1879: CRISPR-associated protein Cas4/Csa1, subtype I-A/APERN 9 279 1.3E-110 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 DFR86_11535 14b91417a2861fff10a8a6cd14fbe2be 281 Pfam PF06023 CRISPR-associated exonuclease Csa1 4 279 5.4E-104 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 DFR86_11535 14b91417a2861fff10a8a6cd14fbe2be 281 PIRSF PIRSF009226 1 280 1.2E-108 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 DFR86_11535 14b91417a2861fff10a8a6cd14fbe2be 281 Gene3D G3DSA:3.90.320.10 153 281 9.2E-7 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal DFR86_06515 dbdda49c8416eab17e1e18e2aaaa6b5f 427 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 415 1.4E-109 T 31-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 DFR86_06515 dbdda49c8416eab17e1e18e2aaaa6b5f 427 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 359 22.033 T 31-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 DFR86_06515 dbdda49c8416eab17e1e18e2aaaa6b5f 427 SUPERFAMILY SSF55681 5 326 8.36E-80 T 31-10-2018 DFR86_06515 dbdda49c8416eab17e1e18e2aaaa6b5f 427 Pfam PF03129 Anticodon binding domain 336 425 5.6E-12 T 31-10-2018 IPR004154 Anticodon-binding DFR86_06515 dbdda49c8416eab17e1e18e2aaaa6b5f 427 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 425 27.017 T 31-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 DFR86_06515 dbdda49c8416eab17e1e18e2aaaa6b5f 427 Gene3D G3DSA:3.40.50.800 333 426 1.7E-16 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily DFR86_06515 dbdda49c8416eab17e1e18e2aaaa6b5f 427 PIRSF PIRSF001549 1 427 1.7E-109 T 31-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 DFR86_06515 dbdda49c8416eab17e1e18e2aaaa6b5f 427 Pfam PF13393 Histidyl-tRNA synthetase 9 319 1.4E-62 T 31-10-2018 DFR86_06515 dbdda49c8416eab17e1e18e2aaaa6b5f 427 SUPERFAMILY SSF52954 335 427 2.42E-15 T 31-10-2018 DFR86_06515 dbdda49c8416eab17e1e18e2aaaa6b5f 427 Gene3D G3DSA:3.30.930.10 3 332 1.3E-92 T 31-10-2018 DFR86_09445 09855475f6bcd39ac29208edb4ad7e73 371 Gene3D G3DSA:3.40.50.300 89 271 5.1E-66 T 31-10-2018 DFR86_09445 09855475f6bcd39ac29208edb4ad7e73 371 Pfam PF04212 MIT (microtubule interacting and transport) domain 11 72 8.1E-11 T 31-10-2018 IPR007330 MIT DFR86_09445 09855475f6bcd39ac29208edb4ad7e73 371 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 136 270 3.8E-39 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_09445 09855475f6bcd39ac29208edb4ad7e73 371 SMART SM00745 4 81 6.0E-14 T 31-10-2018 IPR007330 MIT DFR86_09445 09855475f6bcd39ac29208edb4ad7e73 371 SMART SM00382 132 273 7.1E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_09445 09855475f6bcd39ac29208edb4ad7e73 371 Gene3D G3DSA:1.10.8.60 272 371 2.6E-26 T 31-10-2018 DFR86_09445 09855475f6bcd39ac29208edb4ad7e73 371 Pfam PF09336 Vps4 C terminal oligomerisation domain 324 368 1.3E-8 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal DFR86_09445 09855475f6bcd39ac29208edb4ad7e73 371 Gene3D G3DSA:1.20.58.280 1 82 1.2E-28 T 31-10-2018 DFR86_09445 09855475f6bcd39ac29208edb4ad7e73 371 SUPERFAMILY SSF52540 97 368 2.06E-64 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09445 09855475f6bcd39ac29208edb4ad7e73 371 SUPERFAMILY SSF116846 9 81 1.02E-13 T 31-10-2018 IPR036181 MIT domain superfamily DFR86_08630 46955be976c67e47595a71d359559360 481 Gene3D G3DSA:3.30.930.10 4 282 2.1E-83 T 31-10-2018 DFR86_08630 46955be976c67e47595a71d359559360 481 Gene3D G3DSA:3.40.50.800 284 405 4.4E-33 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily DFR86_08630 46955be976c67e47595a71d359559360 481 SMART SM00946 414 481 7.2E-22 T 31-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR86_08630 46955be976c67e47595a71d359559360 481 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 100 273 1.8E-25 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_08630 46955be976c67e47595a71d359559360 481 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 415 481 9.4E-14 T 31-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR86_08630 46955be976c67e47595a71d359559360 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 1.3E-11 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 DFR86_08630 46955be976c67e47595a71d359559360 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 1.3E-11 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 DFR86_08630 46955be976c67e47595a71d359559360 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 1.3E-11 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 DFR86_08630 46955be976c67e47595a71d359559360 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 1.3E-11 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 DFR86_08630 46955be976c67e47595a71d359559360 481 Pfam PF03129 Anticodon binding domain 290 387 5.6E-21 T 31-10-2018 IPR004154 Anticodon-binding DFR86_08630 46955be976c67e47595a71d359559360 481 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 9 481 4.1E-166 T 31-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR86_08630 46955be976c67e47595a71d359559360 481 Hamap MF_01571 Proline--tRNA ligase [proS]. 5 481 38.683 T 31-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR86_08630 46955be976c67e47595a71d359559360 481 Gene3D G3DSA:3.30.110.30 408 480 3.2E-17 T 31-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR86_08630 46955be976c67e47595a71d359559360 481 SUPERFAMILY SSF55681 10 277 3.06E-81 T 31-10-2018 DFR86_08630 46955be976c67e47595a71d359559360 481 SUPERFAMILY SSF64586 409 481 1.57E-17 T 31-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR86_08630 46955be976c67e47595a71d359559360 481 SUPERFAMILY SSF52954 279 406 4.58E-28 T 31-10-2018 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 9 93 2.0E-27 T 31-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 PRINTS PR01703 Manganese superoxide dismutase signature 76 89 1.3E-15 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 PRINTS PR01703 Manganese superoxide dismutase signature 131 139 1.3E-15 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 PRINTS PR01703 Manganese superoxide dismutase signature 34 47 1.3E-15 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 PRINTS PR01703 Manganese superoxide dismutase signature 13 24 1.3E-15 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 PRINTS PR01703 Manganese superoxide dismutase signature 169 181 1.3E-15 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 171 178 - T 31-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 102 203 7.1E-32 T 31-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 Gene3D G3DSA:2.40.500.20 94 210 1.5E-43 T 31-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 Gene3D G3DSA:1.10.287.990 27 93 4.5E-24 T 31-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 SUPERFAMILY SSF46609 7 98 1.57E-27 T 31-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 SUPERFAMILY SSF54719 96 209 1.44E-38 T 31-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_08790 0d1432ac543864c2a3db2b1b0430e3f2 210 PIRSF PIRSF000349 1 210 2.4E-70 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR86_03215 9adb91b69363b5f5aa44a613180f529b 98 Gene3D G3DSA:3.30.1860.10 1 98 6.9E-23 T 31-10-2018 DFR86_03215 9adb91b69363b5f5aa44a613180f529b 98 Pfam PF04242 Protein of unknown function (DUF424) 12 98 1.4E-25 T 31-10-2018 IPR007355 Protein of unknown function DUF424 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 PRINTS PR01868 ABC transporter family E signature 48 72 8.6E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 PRINTS PR01868 ABC transporter family E signature 152 178 8.6E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 PRINTS PR01868 ABC transporter family E signature 19 34 8.6E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 PRINTS PR01868 ABC transporter family E signature 103 128 8.6E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 PRINTS PR01868 ABC transporter family E signature 75 95 8.6E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 PRINTS PR01868 ABC transporter family E signature 136 152 8.6E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 Pfam PF00037 4Fe-4S binding domain 44 67 9.7E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 32 6.1E-13 T 31-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 SUPERFAMILY SSF54862 4 120 1.55E-18 T 31-10-2018 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 Pfam PF00005 ABC transporter 96 240 3.9E-17 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 Gene3D G3DSA:3.40.50.300 80 327 4.3E-59 T 31-10-2018 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 SUPERFAMILY SSF52540 362 554 3.34E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 ProSitePatterns PS00211 ABC transporters family signature. 213 227 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 Gene3D G3DSA:3.40.50.300 328 595 2.1E-63 T 31-10-2018 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 SMART SM00382 98 288 3.9E-6 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 SMART SM00382 367 538 8.5E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 SUPERFAMILY SSF52540 96 289 1.35E-28 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 Pfam PF00005 ABC transporter 363 487 1.6E-19 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_06470 b31a65d2009ecc61fceeb0bef3c05947 600 Gene3D G3DSA:3.30.70.20 9 79 8.7E-11 T 31-10-2018 DFR86_04230 eedf509ecc48f0905eaab73bf42da784 412 SUPERFAMILY SSF56176 27 207 5.14E-23 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_04230 eedf509ecc48f0905eaab73bf42da784 412 Pfam PF01565 FAD binding domain 45 180 1.6E-20 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_04230 eedf509ecc48f0905eaab73bf42da784 412 Pfam PF02913 FAD linked oxidases, C-terminal domain 384 411 2.9E-5 T 31-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 DFR86_04230 eedf509ecc48f0905eaab73bf42da784 412 SUPERFAMILY SSF55103 220 412 3.6E-8 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DFR86_04230 eedf509ecc48f0905eaab73bf42da784 412 Gene3D G3DSA:3.30.465.40 14 230 4.5E-22 T 31-10-2018 DFR86_04230 eedf509ecc48f0905eaab73bf42da784 412 Gene3D G3DSA:1.10.45.10 382 412 5.7E-7 T 31-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 DFR86_09925 55ed704275dca919d509d0dc7e622b57 460 Gene3D G3DSA:3.20.20.70 1 270 1.2E-87 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_09925 55ed704275dca919d509d0dc7e622b57 460 Gene3D G3DSA:1.10.238.260 272 379 2.4E-27 T 31-10-2018 DFR86_09925 55ed704275dca919d509d0dc7e622b57 460 Gene3D G3DSA:3.30.70.920 386 460 5.1E-17 T 31-10-2018 DFR86_09925 55ed704275dca919d509d0dc7e622b57 460 SUPERFAMILY SSF54909 385 459 3.62E-14 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR86_09925 55ed704275dca919d509d0dc7e622b57 460 Pfam PF01037 Lrp/AsnC ligand binding domain 388 458 4.1E-15 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR86_09925 55ed704275dca919d509d0dc7e622b57 460 TIGRFAM TIGR02146 LysS_fung_arch: homocitrate synthase 5 352 4.2E-164 T 31-10-2018 IPR011872 Homocitrate synthase, fungi/archaea GO:0004410|GO:0019752|GO:0019878|GO:0046912 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 DFR86_09925 55ed704275dca919d509d0dc7e622b57 460 SUPERFAMILY SSF51569 3 281 6.59E-79 T 31-10-2018 DFR86_09925 55ed704275dca919d509d0dc7e622b57 460 Pfam PF00682 HMGL-like 3 263 9.8E-74 T 31-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 DFR86_02460 de246c025d0e87e76b5d7d0b21c7f86d 496 Gene3D G3DSA:3.40.50.300 274 477 9.7E-64 T 31-10-2018 DFR86_02460 de246c025d0e87e76b5d7d0b21c7f86d 496 Gene3D G3DSA:3.40.50.300 107 254 2.1E-28 T 31-10-2018 DFR86_02460 de246c025d0e87e76b5d7d0b21c7f86d 496 Pfam PF09378 HAS barrel domain 4 75 5.5E-7 T 31-10-2018 IPR018538 Helicase HerA, barrel domain DFR86_02460 de246c025d0e87e76b5d7d0b21c7f86d 496 Pfam PF01935 Domain of unknown function DUF87 121 333 1.5E-43 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR86_02460 de246c025d0e87e76b5d7d0b21c7f86d 496 SUPERFAMILY SSF52540 97 466 3.91E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_02460 de246c025d0e87e76b5d7d0b21c7f86d 496 Pfam PF05872 Bacterial protein of unknown function (DUF853) 352 448 2.5E-6 T 31-10-2018 IPR033186 Helicase HerA-like C-terminal DFR86_11145 65e96739d3359639f765e51fd5b93460 289 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 17 247 4.8E-43 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR86_11145 65e96739d3359639f765e51fd5b93460 289 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 131 157 4.6E-38 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR86_11145 65e96739d3359639f765e51fd5b93460 289 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 183 211 4.6E-38 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR86_11145 65e96739d3359639f765e51fd5b93460 289 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 113 131 4.6E-38 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR86_11145 65e96739d3359639f765e51fd5b93460 289 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 16 43 4.6E-38 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR86_11145 65e96739d3359639f765e51fd5b93460 289 Pfam PF00902 Sec-independent protein translocase protein (TatC) 19 240 7.1E-51 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR86_11145 65e96739d3359639f765e51fd5b93460 289 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 9 270 13.778 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR86_07680 7144adb1bf92d361d9a77b36d927b2a5 815 SUPERFAMILY SSF82866 626 806 1.57E-23 T 31-10-2018 DFR86_07680 7144adb1bf92d361d9a77b36d927b2a5 815 Pfam PF03176 MMPL family 647 810 3.6E-29 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 DFR86_07680 7144adb1bf92d361d9a77b36d927b2a5 815 Pfam PF03176 MMPL family 284 437 1.6E-20 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 DFR86_07680 7144adb1bf92d361d9a77b36d927b2a5 815 SUPERFAMILY SSF82866 247 452 1.22E-19 T 31-10-2018 DFR86_04570 40a7af9f744f5bf8eabca0cf64b599cc 267 Pfam PF13478 XdhC Rossmann domain 85 223 7.7E-21 T 31-10-2018 IPR027051 XdhC Rossmann domain DFR86_04570 40a7af9f744f5bf8eabca0cf64b599cc 267 Gene3D G3DSA:3.40.50.720 83 243 3.8E-23 T 31-10-2018 DFR86_04295 a4e25cfa5fbfca5d4427c54d7abced8c 522 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 376 516 1.0E-16 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR86_04295 a4e25cfa5fbfca5d4427c54d7abced8c 522 Gene3D G3DSA:3.40.50.970 359 522 6.9E-25 T 31-10-2018 DFR86_04295 a4e25cfa5fbfca5d4427c54d7abced8c 522 SUPERFAMILY SSF52518 16 184 5.89E-29 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_04295 a4e25cfa5fbfca5d4427c54d7abced8c 522 SUPERFAMILY SSF52518 376 519 5.14E-23 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_04295 a4e25cfa5fbfca5d4427c54d7abced8c 522 Gene3D G3DSA:3.40.50.1220 187 328 1.4E-8 T 31-10-2018 DFR86_04295 a4e25cfa5fbfca5d4427c54d7abced8c 522 SUPERFAMILY SSF52467 158 342 1.86E-12 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_04295 a4e25cfa5fbfca5d4427c54d7abced8c 522 Gene3D G3DSA:3.40.50.970 2 179 3.7E-41 T 31-10-2018 DFR86_04295 a4e25cfa5fbfca5d4427c54d7abced8c 522 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 173 1.4E-37 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR86_10285 7fd13375416786e445a5daa308f63c48 396 Gene3D G3DSA:1.20.1250.20 5 197 6.7E-17 T 31-10-2018 DFR86_10285 7fd13375416786e445a5daa308f63c48 396 Pfam PF07690 Major Facilitator Superfamily 12 338 1.7E-27 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_10285 7fd13375416786e445a5daa308f63c48 396 SUPERFAMILY SSF103473 5 393 8.24E-44 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_10285 7fd13375416786e445a5daa308f63c48 396 Gene3D G3DSA:1.20.1250.20 202 393 9.8E-16 T 31-10-2018 DFR86_11135 a65043145ecf09f0fa8d028fcef6274a 104 Pfam PF02416 mttA/Hcf106 family 7 55 1.0E-10 T 31-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 DFR86_11135 a65043145ecf09f0fa8d028fcef6274a 104 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 51 5.2E-18 T 31-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 DFR86_11020 2f8b060128983b999c2c7d642db15416 183 Pfam PF01661 Macro domain 27 140 4.5E-38 T 31-10-2018 IPR002589 Macro domain DFR86_11020 2f8b060128983b999c2c7d642db15416 183 SUPERFAMILY SSF52949 5 175 2.19E-62 T 31-10-2018 DFR86_11020 2f8b060128983b999c2c7d642db15416 183 SMART SM00506 10 140 8.6E-50 T 31-10-2018 IPR002589 Macro domain DFR86_11020 2f8b060128983b999c2c7d642db15416 183 Gene3D G3DSA:3.40.220.10 2 175 2.1E-64 T 31-10-2018 DFR86_00755 cd734fe2f9e25cc2ca2ce54ff1381d8b 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 263 3.8E-16 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_00755 cd734fe2f9e25cc2ca2ce54ff1381d8b 272 SUPERFAMILY SSF161098 43 263 2.09E-46 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_00755 cd734fe2f9e25cc2ca2ce54ff1381d8b 272 Gene3D G3DSA:1.10.3720.10 2 266 1.2E-48 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_06780 3e312760edc2df1a780d1000706b9b11 83 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 8 83 3.0E-33 T 31-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06780 3e312760edc2df1a780d1000706b9b11 83 ProSitePatterns PS00050 Ribosomal protein L23 signature. 61 76 - T 31-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06780 3e312760edc2df1a780d1000706b9b11 83 Gene3D G3DSA:3.30.70.330 3 83 2.8E-32 T 31-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily DFR86_06780 3e312760edc2df1a780d1000706b9b11 83 SUPERFAMILY SSF54189 1 76 1.04E-21 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06780 3e312760edc2df1a780d1000706b9b11 83 Pfam PF00276 Ribosomal protein L23 4 70 1.4E-12 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 DFR86_06780 3e312760edc2df1a780d1000706b9b11 83 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 3 83 23.097 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 DFR86_03555 434f5ec9c679b060dd6839b52876d383 409 Pfam PF07690 Major Facilitator Superfamily 41 307 1.0E-15 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_03555 434f5ec9c679b060dd6839b52876d383 409 SUPERFAMILY SSF103473 1 395 2.62E-44 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_03555 434f5ec9c679b060dd6839b52876d383 409 Gene3D G3DSA:1.20.1250.20 9 404 5.6E-46 T 31-10-2018 DFR86_03555 434f5ec9c679b060dd6839b52876d383 409 ProSitePatterns PS00216 Sugar transport proteins signature 1. 277 294 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_08850 545c43c25a1ce037e775445128a030bc 265 Gene3D G3DSA:3.40.50.720 101 228 1.7E-65 T 31-10-2018 DFR86_08850 545c43c25a1ce037e775445128a030bc 265 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 93 2.6E-24 T 31-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 DFR86_08850 545c43c25a1ce037e775445128a030bc 265 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 261 28.699 T 31-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 DFR86_08850 545c43c25a1ce037e775445128a030bc 265 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 109 193 1.7E-9 T 31-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase DFR86_08850 545c43c25a1ce037e775445128a030bc 265 SUPERFAMILY SSF51735 102 258 1.51E-30 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_08850 545c43c25a1ce037e775445128a030bc 265 Gene3D G3DSA:3.40.50.10860 10 249 1.7E-65 T 31-10-2018 DFR86_08850 545c43c25a1ce037e775445128a030bc 265 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 8 257 1.9E-60 T 31-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 DFR86_08850 545c43c25a1ce037e775445128a030bc 265 SUPERFAMILY SSF53223 1 101 1.78E-26 T 31-10-2018 DFR86_04020 b02a3ed41c4e424ff0766d4398e542d9 639 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 54 79 - T 31-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 DFR86_04020 b02a3ed41c4e424ff0766d4398e542d9 639 SUPERFAMILY SSF56762 13 618 2.35E-86 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_04020 b02a3ed41c4e424ff0766d4398e542d9 639 Gene3D G3DSA:1.10.645.10 14 618 5.5E-195 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_04020 b02a3ed41c4e424ff0766d4398e542d9 639 Pfam PF00374 Nickel-dependent hydrogenase 54 136 7.2E-15 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR86_04020 b02a3ed41c4e424ff0766d4398e542d9 639 Pfam PF00374 Nickel-dependent hydrogenase 181 618 1.0E-30 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR86_02680 5dcdac6daa3448fa772ec38600f1894f 280 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 67 75 - T 31-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 DFR86_02680 5dcdac6daa3448fa772ec38600f1894f 280 Pfam PF01261 Xylose isomerase-like TIM barrel 25 226 4.0E-23 T 31-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain DFR86_02680 5dcdac6daa3448fa772ec38600f1894f 280 SMART SM00518 8 271 2.7E-59 T 31-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 DFR86_02680 5dcdac6daa3448fa772ec38600f1894f 280 Gene3D G3DSA:3.20.20.150 7 276 3.6E-38 T 31-10-2018 DFR86_02680 5dcdac6daa3448fa772ec38600f1894f 280 SUPERFAMILY SSF51658 4 273 7.93E-50 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily DFR86_02120 e85836b7f3f665bcbb82ce72a7e925dd 318 Pfam PF00586 AIR synthase related protein, N-terminal domain 28 121 2.2E-13 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR86_02120 e85836b7f3f665bcbb82ce72a7e925dd 318 SUPERFAMILY SSF55326 15 122 1.27E-19 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_02120 e85836b7f3f665bcbb82ce72a7e925dd 318 SUPERFAMILY SSF56042 135 287 7.33E-16 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_02120 e85836b7f3f665bcbb82ce72a7e925dd 318 Gene3D G3DSA:3.30.1330.10 4 130 3.7E-19 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_02120 e85836b7f3f665bcbb82ce72a7e925dd 318 Gene3D G3DSA:3.90.650.10 131 304 2.4E-23 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_02120 e85836b7f3f665bcbb82ce72a7e925dd 318 PIRSF PIRSF005644 1 306 6.4E-61 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE DFR86_02120 e85836b7f3f665bcbb82ce72a7e925dd 318 Pfam PF02769 AIR synthase related protein, C-terminal domain 142 286 5.9E-11 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR86_09640 52331fb818157714bf155a9be4da3204 562 Gene3D G3DSA:1.10.560.10 26 530 2.2E-201 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR86_09640 52331fb818157714bf155a9be4da3204 562 SUPERFAMILY SSF52029 219 385 7.95E-58 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR86_09640 52331fb818157714bf155a9be4da3204 562 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 87 95 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_09640 52331fb818157714bf155a9be4da3204 562 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 38 50 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_09640 52331fb818157714bf155a9be4da3204 562 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 57 75 1.2E-32 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_09640 52331fb818157714bf155a9be4da3204 562 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 35 51 1.2E-32 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_09640 52331fb818157714bf155a9be4da3204 562 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 87 106 1.2E-32 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_09640 52331fb818157714bf155a9be4da3204 562 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 380 402 1.2E-32 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_09640 52331fb818157714bf155a9be4da3204 562 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 414 426 1.2E-32 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_09640 52331fb818157714bf155a9be4da3204 562 Gene3D G3DSA:3.50.7.10 223 377 2.2E-201 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR86_09640 52331fb818157714bf155a9be4da3204 562 SUPERFAMILY SSF48592 16 531 5.49E-87 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR86_09640 52331fb818157714bf155a9be4da3204 562 SUPERFAMILY SSF54849 154 410 1.28E-22 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR86_09640 52331fb818157714bf155a9be4da3204 562 Gene3D G3DSA:3.30.260.10 145 412 2.2E-201 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR86_09640 52331fb818157714bf155a9be4da3204 562 Pfam PF00118 TCP-1/cpn60 chaperonin family 33 533 1.2E-175 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 DFR86_09640 52331fb818157714bf155a9be4da3204 562 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 6 532 1.1E-241 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 DFR86_09640 52331fb818157714bf155a9be4da3204 562 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 59 75 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_02880 9b943f47fd8d1ae3af5d2b399eff9802 402 Gene3D G3DSA:1.20.1250.20 10 378 3.3E-31 T 31-10-2018 DFR86_02880 9b943f47fd8d1ae3af5d2b399eff9802 402 SUPERFAMILY SSF103473 11 380 6.54E-41 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_02880 9b943f47fd8d1ae3af5d2b399eff9802 402 Pfam PF07690 Major Facilitator Superfamily 17 306 3.1E-24 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_03965 786f92cee6e8c4b7f6a856308ffac460 147 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 137 5.2E-27 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 DFR86_03965 786f92cee6e8c4b7f6a856308ffac460 147 Gene3D G3DSA:3.30.2320.50 1 73 2.9E-17 T 31-10-2018 DFR86_03965 786f92cee6e8c4b7f6a856308ffac460 147 PIRSF PIRSF004761 1 141 7.5E-36 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 DFR86_03965 786f92cee6e8c4b7f6a856308ffac460 147 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 138 19.01 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 DFR86_03965 786f92cee6e8c4b7f6a856308ffac460 147 Gene3D G3DSA:2.20.28.10 74 128 4.1E-15 T 31-10-2018 DFR86_04640 cd40da6da0bbce536a3c3ce8a89a1979 187 Pfam PF01184 GPR1/FUN34/yaaH family 3 173 2.3E-46 T 31-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 DFR86_04640 cd40da6da0bbce536a3c3ce8a89a1979 187 ProSitePatterns PS01114 GPR1/FUN34/yaaH family signature. 8 17 - T 31-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 DFR86_09615 4ac9c52b590f8b9f0ff23473931d780c 205 Pfam PF14544 Domain of unknown function (DUF4443) 120 184 1.3E-4 T 31-10-2018 IPR029349 Domain of unknown function DUF4443 DFR86_09615 4ac9c52b590f8b9f0ff23473931d780c 205 Gene3D G3DSA:3.30.1360.30 97 202 3.4E-6 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 DFR86_09615 4ac9c52b590f8b9f0ff23473931d780c 205 SUPERFAMILY SSF46785 28 88 1.3E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_09615 4ac9c52b590f8b9f0ff23473931d780c 205 SUPERFAMILY SSF55261 94 196 1.05E-17 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 DFR86_09615 4ac9c52b590f8b9f0ff23473931d780c 205 Gene3D G3DSA:1.10.10.10 8 96 4.8E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_09155 edf2174c8f6953934ab9eaac6f59db1d 308 Gene3D G3DSA:3.20.20.70 1 301 2.5E-74 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_09155 edf2174c8f6953934ab9eaac6f59db1d 308 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 16 27 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_09155 edf2174c8f6953934ab9eaac6f59db1d 308 Pfam PF13353 4Fe-4S single cluster domain 17 110 5.1E-8 T 31-10-2018 DFR86_09155 edf2174c8f6953934ab9eaac6f59db1d 308 SMART SM00729 10 214 8.4E-5 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_09155 edf2174c8f6953934ab9eaac6f59db1d 308 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 1 305 2.0E-118 T 31-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 DFR86_09155 edf2174c8f6953934ab9eaac6f59db1d 308 SUPERFAMILY SSF102114 3 293 3.14E-67 T 31-10-2018 DFR86_09155 edf2174c8f6953934ab9eaac6f59db1d 308 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 1 305 43.208 T 31-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 DFR86_09155 edf2174c8f6953934ab9eaac6f59db1d 308 Pfam PF04055 Radical SAM superfamily 14 168 6.8E-25 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_09155 edf2174c8f6953934ab9eaac6f59db1d 308 Pfam PF06463 Molybdenum Cofactor Synthesis C 178 305 1.2E-25 T 31-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_08660 5e0c4b1ffcd9ad6a990bb879e1208be0 190 SUPERFAMILY SSF160527 81 189 3.14E-15 T 31-10-2018 DFR86_08660 5e0c4b1ffcd9ad6a990bb879e1208be0 190 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 1 189 10.648 T 31-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08660 5e0c4b1ffcd9ad6a990bb879e1208be0 190 Gene3D G3DSA:3.30.2320.30 81 189 4.7E-11 T 31-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_10340 45ef4ecbab74f3e6a6e85aed61e20bd6 187 SUPERFAMILY SSF52499 10 174 2.09E-42 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 DFR86_10340 45ef4ecbab74f3e6a6e85aed61e20bd6 187 Pfam PF00857 Isochorismatase family 18 170 4.5E-35 T 31-10-2018 IPR000868 Isochorismatase-like GO:0003824 DFR86_10340 45ef4ecbab74f3e6a6e85aed61e20bd6 187 Gene3D G3DSA:3.40.50.850 6 187 2.1E-36 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 DFR86_06290 c93dfc67fbd9fb449dca72242d445395 473 SUPERFAMILY SSF89095 293 399 4.32E-29 T 31-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 DFR86_06290 c93dfc67fbd9fb449dca72242d445395 473 Gene3D G3DSA:1.10.10.410 411 472 7.0E-21 T 31-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal DFR86_06290 c93dfc67fbd9fb449dca72242d445395 473 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 3 470 2.1E-160 T 31-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 DFR86_06290 c93dfc67fbd9fb449dca72242d445395 473 Pfam PF02934 GatB/GatE catalytic domain 3 285 2.7E-98 T 31-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 DFR86_06290 c93dfc67fbd9fb449dca72242d445395 473 Gene3D G3DSA:1.10.150.380 293 410 9.1E-31 T 31-10-2018 DFR86_06290 c93dfc67fbd9fb449dca72242d445395 473 SMART SM00845 324 470 8.4E-60 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 DFR86_06290 c93dfc67fbd9fb449dca72242d445395 473 SUPERFAMILY SSF55931 3 292 5.89E-98 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR86_06290 c93dfc67fbd9fb449dca72242d445395 473 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 1 471 34.03 T 31-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 DFR86_06290 c93dfc67fbd9fb449dca72242d445395 473 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 147 161 - T 31-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 DFR86_06290 c93dfc67fbd9fb449dca72242d445395 473 Pfam PF02637 GatB domain 324 470 9.7E-45 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 DFR86_05040 2d0f086f1cfa973a6dda0f6861a0a3ec 350 SUPERFAMILY SSF51556 180 347 9.6E-19 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_05040 2d0f086f1cfa973a6dda0f6861a0a3ec 350 Gene3D G3DSA:3.20.20.140 1 348 1.7E-74 T 31-10-2018 DFR86_05040 2d0f086f1cfa973a6dda0f6861a0a3ec 350 Pfam PF04909 Amidohydrolase 2 348 3.2E-32 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_08205 0c72067b4611bee275bbace5612cba89 131 SUPERFAMILY SSF47598 2 45 6.52E-6 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR86_08205 0c72067b4611bee275bbace5612cba89 131 Gene3D G3DSA:3.30.70.1150 29 126 1.1E-23 T 31-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal DFR86_08205 0c72067b4611bee275bbace5612cba89 131 Pfam PF08753 NikR C terminal nickel binding domain 53 125 1.4E-20 T 31-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal DFR86_08205 0c72067b4611bee275bbace5612cba89 131 SUPERFAMILY SSF55021 51 128 3.89E-17 T 31-10-2018 DFR86_08205 0c72067b4611bee275bbace5612cba89 131 Pfam PF10929 Protein of unknown function (DUF2811) 7 52 2.4E-4 T 31-10-2018 IPR021231 Protein of unknown function DUF2811 DFR86_07915 032df504a6c5c9ab70db71bf02c03519 313 Pfam PF00107 Zinc-binding dehydrogenase 160 274 1.0E-12 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR86_07915 032df504a6c5c9ab70db71bf02c03519 313 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 116 3.0E-13 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR86_07915 032df504a6c5c9ab70db71bf02c03519 313 Gene3D G3DSA:3.90.180.10 1 313 4.3E-59 T 31-10-2018 DFR86_07915 032df504a6c5c9ab70db71bf02c03519 313 SUPERFAMILY SSF50129 1 154 2.28E-27 T 31-10-2018 IPR011032 GroES-like superfamily DFR86_07915 032df504a6c5c9ab70db71bf02c03519 313 SMART SM00829 4 310 6.3E-5 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR86_07915 032df504a6c5c9ab70db71bf02c03519 313 SUPERFAMILY SSF51735 127 284 2.1E-26 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_00420 81ac6ffb6538368e6252753adc8488ba 401 SUPERFAMILY SSF53335 17 352 3.25E-16 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_00420 81ac6ffb6538368e6252753adc8488ba 401 Gene3D G3DSA:3.40.50.150 5 98 4.6E-12 T 31-10-2018 DFR86_00420 81ac6ffb6538368e6252753adc8488ba 401 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 277 283 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DFR86_00420 81ac6ffb6538368e6252753adc8488ba 401 Pfam PF01555 DNA methylase 274 361 1.0E-5 T 31-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 DFR86_00420 81ac6ffb6538368e6252753adc8488ba 401 Pfam PF01555 DNA methylase 19 60 2.6E-5 T 31-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 DFR86_00420 81ac6ffb6538368e6252753adc8488ba 401 Gene3D G3DSA:3.40.50.150 259 391 2.7E-14 T 31-10-2018 DFR86_01195 300c89ac7ed81ddc03c5188e37f7c487 161 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 124 145 - T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR86_01195 300c89ac7ed81ddc03c5188e37f7c487 161 Pfam PF09637 Med18 protein 25 104 9.2E-5 T 31-10-2018 IPR019095 Mediator complex, subunit Med18 GO:0003712|GO:0006357|GO:0016592 Reactome: R-HSA-1989781|Reactome: R-HSA-381340 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 248 260 - T 31-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 Pfam PF00490 Delta-aminolevulinic acid dehydratase 7 329 4.8E-142 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 PIRSF PIRSF001415 1 333 1.1E-150 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 196 215 2.4E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 248 264 2.4E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 124 138 2.4E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 304 323 2.4E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 158 177 2.4E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 274 289 2.4E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 SMART SM01004 4 330 2.3E-220 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 SUPERFAMILY SSF51569 3 332 5.13E-136 T 31-10-2018 DFR86_07125 a733bfa01a7de36859f640cdaf3ff9f0 336 Gene3D G3DSA:3.20.20.70 1 336 5.5E-150 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_06810 3580e5a8287b4e9973d0b829482cc234 86 SUPERFAMILY SSF101744 2 85 9.07E-18 T 31-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 DFR86_06810 3580e5a8287b4e9973d0b829482cc234 86 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 2 80 14.46 T 31-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 DFR86_06810 3580e5a8287b4e9973d0b829482cc234 86 Pfam PF01868 Domain of unknown function UPF0086 4 81 9.8E-11 T 31-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 DFR86_06810 3580e5a8287b4e9973d0b829482cc234 86 SMART SM00538 1 86 0.0038 T 31-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 DFR86_06810 3580e5a8287b4e9973d0b829482cc234 86 Gene3D G3DSA:2.30.30.210 1 85 2.9E-18 T 31-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 DFR86_10725 280d00122b432fedb933249e9707c886 356 SUPERFAMILY SSF52768 2 324 5.76E-71 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily DFR86_10725 280d00122b432fedb933249e9707c886 356 Gene3D G3DSA:3.40.800.20 7 353 1.2E-66 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR86_10725 280d00122b432fedb933249e9707c886 356 PRINTS PR01270 Histone deacetylase superfamily signature 118 141 2.4E-7 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR86_10725 280d00122b432fedb933249e9707c886 356 PRINTS PR01270 Histone deacetylase superfamily signature 251 261 2.4E-7 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR86_10725 280d00122b432fedb933249e9707c886 356 Pfam PF00850 Histone deacetylase domain 26 306 8.1E-54 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR86_06700 3bbf4de918c51dcdbc178d7ad52a7267 244 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 5 241 58.115 T 31-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 DFR86_06700 3bbf4de918c51dcdbc178d7ad52a7267 244 Gene3D G3DSA:3.30.230.70 3 242 2.9E-72 T 31-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR86_06700 3bbf4de918c51dcdbc178d7ad52a7267 244 SUPERFAMILY SSF55666 153 240 2.36E-23 T 31-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR86_06700 3bbf4de918c51dcdbc178d7ad52a7267 244 Pfam PF03725 3' exoribonuclease family, domain 2 156 221 2.5E-13 T 31-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR86_06700 3bbf4de918c51dcdbc178d7ad52a7267 244 SUPERFAMILY SSF54211 8 180 1.32E-44 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_06700 3bbf4de918c51dcdbc178d7ad52a7267 244 Pfam PF01138 3' exoribonuclease family, domain 1 24 153 1.8E-34 T 31-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR86_06700 3bbf4de918c51dcdbc178d7ad52a7267 244 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 8 237 2.3E-116 T 31-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 DFR86_01840 db7df4ce4c707af7a35357afcee05fdc 121 SUPERFAMILY SSF54637 4 120 2.54E-40 T 31-10-2018 IPR029069 HotDog domain superfamily DFR86_01840 db7df4ce4c707af7a35357afcee05fdc 121 PIRSF PIRSF014972 3 121 3.8E-40 T 31-10-2018 IPR025540 Fluoroacetyl-CoA thioesterase DFR86_01840 db7df4ce4c707af7a35357afcee05fdc 121 Gene3D G3DSA:3.10.129.10 1 121 4.8E-41 T 31-10-2018 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 Gene3D G3DSA:1.10.40.30 343 375 1.2E-99 T 31-10-2018 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 Gene3D G3DSA:1.20.200.10 108 342 1.2E-99 T 31-10-2018 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 PRINTS PR00145 Argininosuccinate lyase family signature 220 244 2.1E-31 T 31-10-2018 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 PRINTS PR00145 Argininosuccinate lyase family signature 90 112 2.1E-31 T 31-10-2018 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 PRINTS PR00145 Argininosuccinate lyase family signature 182 198 2.1E-31 T 31-10-2018 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 PRINTS PR00145 Argininosuccinate lyase family signature 262 278 2.1E-31 T 31-10-2018 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 PRINTS PR00145 Argininosuccinate lyase family signature 297 316 2.1E-31 T 31-10-2018 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 PRINTS PR00145 Argininosuccinate lyase family signature 131 151 2.1E-31 T 31-10-2018 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 TIGRFAM TIGR00838 argH: argininosuccinate lyase 8 373 6.6E-94 T 31-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 Hamap MF_00006 Argininosuccinate lyase [argH]. 1 411 30.398 T 31-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 Gene3D G3DSA:1.10.275.10 34 218 1.2E-99 T 31-10-2018 IPR024083 Fumarase/histidase, N-terminal DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 SUPERFAMILY SSF48557 5 414 2.36E-86 T 31-10-2018 IPR008948 L-Aspartase-like GO:0003824 DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 Pfam PF00206 Lyase 25 287 6.2E-45 T 31-10-2018 IPR022761 Fumarate lyase, N-terminal DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 PRINTS PR00149 Fumarate lyase superfamily signature 220 247 5.3E-18 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 5.3E-18 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 PRINTS PR00149 Fumarate lyase superfamily signature 91 109 5.3E-18 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_08295 3d1919c3476ba386578cd440a8405df0 444 PRINTS PR00149 Fumarate lyase superfamily signature 262 278 5.3E-18 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_07085 041e01f2ac4eb2a2f6b1f3b589dfa3ba 327 SUPERFAMILY SSF56281 24 317 1.26E-28 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_07085 041e01f2ac4eb2a2f6b1f3b589dfa3ba 327 Gene3D G3DSA:3.60.15.10 2 166 4.0E-23 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_10540 b9c8251a142f09f9a541720ac4892fa0 214 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 105 207 7.2E-21 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_10540 b9c8251a142f09f9a541720ac4892fa0 214 Gene3D G3DSA:3.40.50.12280 77 214 1.5E-37 T 31-10-2018 DFR86_10540 b9c8251a142f09f9a541720ac4892fa0 214 SUPERFAMILY SSF56770 87 209 4.06E-43 T 31-10-2018 DFR86_10540 b9c8251a142f09f9a541720ac4892fa0 214 SUPERFAMILY SSF54862 42 109 1.41E-5 T 31-10-2018 DFR86_10985 16a399b3d3ecedd8b79fb257d87c2ec0 241 Gene3D G3DSA:3.10.620.30 67 229 2.6E-26 T 31-10-2018 DFR86_10985 16a399b3d3ecedd8b79fb257d87c2ec0 241 SMART SM00460 139 198 1.8E-17 T 31-10-2018 IPR002931 Transglutaminase-like DFR86_10985 16a399b3d3ecedd8b79fb257d87c2ec0 241 SUPERFAMILY SSF54001 131 218 1.68E-22 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily DFR86_10985 16a399b3d3ecedd8b79fb257d87c2ec0 241 Pfam PF01841 Transglutaminase-like superfamily 122 196 7.4E-16 T 31-10-2018 IPR002931 Transglutaminase-like DFR86_10250 004ba1d8e17fbcdafce96a2626782acb 143 Gene3D G3DSA:1.10.10.10 15 113 5.3E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10250 004ba1d8e17fbcdafce96a2626782acb 143 Pfam PF03551 Transcriptional regulator PadR-like family 24 91 8.7E-17 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal DFR86_10250 004ba1d8e17fbcdafce96a2626782acb 143 SUPERFAMILY SSF46785 20 95 2.16E-21 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 112 195 6.1E-28 T 31-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 SUPERFAMILY SSF48168 18 194 2.22E-28 T 31-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 Pfam PF03477 ATP cone domain 13 89 1.1E-7 T 31-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 118 786 1.1E-233 T 31-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 Gene3D G3DSA:3.20.70.20 104 375 2.3E-77 T 31-10-2018 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 Gene3D G3DSA:3.20.70.20 376 792 8.7E-142 T 31-10-2018 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 SUPERFAMILY SSF51998 197 789 5.49E-152 T 31-10-2018 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 115 774 7.1E-120 T 31-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 Pfam PF02867 Ribonucleotide reductase, barrel domain 198 776 2.3E-189 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 PRINTS PR01183 Ribonucleotide reductase large chain signature 481 504 7.6E-41 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 PRINTS PR01183 Ribonucleotide reductase large chain signature 519 541 7.6E-41 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 PRINTS PR01183 Ribonucleotide reductase large chain signature 630 657 7.6E-41 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 PRINTS PR01183 Ribonucleotide reductase large chain signature 547 570 7.6E-41 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR86_09680 fb229109afdcdcfd3ab35618065e4eae 840 PRINTS PR01183 Ribonucleotide reductase large chain signature 278 297 7.6E-41 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR86_04650 4e6c9d29051e741662d1372a3a44677d 206 Pfam PF04967 HTH DNA binding domain 146 197 7.4E-20 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR86_05625 66e7fa58179b8e050ebe394866411819 300 SMART SM00116 244 292 8.4E-13 T 31-10-2018 IPR000644 CBS domain DFR86_05625 66e7fa58179b8e050ebe394866411819 300 SMART SM00116 181 229 2.9E-8 T 31-10-2018 IPR000644 CBS domain DFR86_05625 66e7fa58179b8e050ebe394866411819 300 SUPERFAMILY SSF46785 4 78 5.66E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_05625 66e7fa58179b8e050ebe394866411819 300 SUPERFAMILY SSF54631 170 293 1.02E-31 T 31-10-2018 DFR86_05625 66e7fa58179b8e050ebe394866411819 300 Pfam PF00571 CBS domain 174 228 6.8E-10 T 31-10-2018 IPR000644 CBS domain DFR86_05625 66e7fa58179b8e050ebe394866411819 300 Pfam PF00571 CBS domain 237 292 5.3E-12 T 31-10-2018 IPR000644 CBS domain DFR86_05625 66e7fa58179b8e050ebe394866411819 300 Gene3D G3DSA:3.10.580.10 231 293 7.3E-15 T 31-10-2018 DFR86_05625 66e7fa58179b8e050ebe394866411819 300 Gene3D G3DSA:3.10.580.10 127 230 8.4E-14 T 31-10-2018 DFR86_05625 66e7fa58179b8e050ebe394866411819 300 Gene3D G3DSA:1.10.10.10 10 74 2.6E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_05625 66e7fa58179b8e050ebe394866411819 300 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 3 79 1.3E-34 T 31-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 DFR86_05625 66e7fa58179b8e050ebe394866411819 300 PIRSF PIRSF005063 1 299 3.5E-120 T 31-10-2018 IPR016436 Uncharacterised conserved protein UCP005063, CBS-type DFR86_07300 7ec9e18be9ff510a417e35ed0aed3475 283 Gene3D G3DSA:3.30.1490.20 104 172 1.8E-23 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_07300 7ec9e18be9ff510a417e35ed0aed3475 283 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 3 277 1.1E-77 T 31-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 DFR86_07300 7ec9e18be9ff510a417e35ed0aed3475 283 SUPERFAMILY SSF52440 3 88 1.73E-24 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR86_07300 7ec9e18be9ff510a417e35ed0aed3475 283 Gene3D G3DSA:3.40.50.20 2 102 2.1E-26 T 31-10-2018 DFR86_07300 7ec9e18be9ff510a417e35ed0aed3475 283 Gene3D G3DSA:3.30.470.80 173 283 2.7E-27 T 31-10-2018 DFR86_07300 7ec9e18be9ff510a417e35ed0aed3475 283 SUPERFAMILY SSF56059 78 277 1.34E-44 T 31-10-2018 DFR86_07300 7ec9e18be9ff510a417e35ed0aed3475 283 Pfam PF08443 RimK-like ATP-grasp domain 87 276 1.2E-32 T 31-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 DFR86_07300 7ec9e18be9ff510a417e35ed0aed3475 283 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 3 283 6.3E-111 T 31-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 DFR86_04260 e6fada399be474a16873f66d08a7bf2f 505 Gene3D G3DSA:1.20.1740.10 15 491 2.6E-9 T 31-10-2018 DFR86_04260 e6fada399be474a16873f66d08a7bf2f 505 PIRSF PIRSF006060 1 504 4.1E-32 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04260 e6fada399be474a16873f66d08a7bf2f 505 Pfam PF13520 Amino acid permease 46 470 2.8E-21 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_07530 f89252f11057b51c1629ebc0a98553f6 126 Gene3D G3DSA:1.10.10.10 11 116 2.1E-29 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_07530 f89252f11057b51c1629ebc0a98553f6 126 Pfam PF02002 TFIIE alpha subunit 15 117 5.6E-10 T 31-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR86_07530 f89252f11057b51c1629ebc0a98553f6 126 SUPERFAMILY SSF46785 17 115 1.16E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_03605 bdf7de2759ce522d4c4fb1fb30bb1833 370 SUPERFAMILY SSF103473 7 365 5.36E-45 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_03605 bdf7de2759ce522d4c4fb1fb30bb1833 370 Gene3D G3DSA:1.20.1250.20 183 370 1.3E-13 T 31-10-2018 DFR86_03605 bdf7de2759ce522d4c4fb1fb30bb1833 370 Gene3D G3DSA:1.20.1250.20 1 182 2.6E-30 T 31-10-2018 DFR86_03605 bdf7de2759ce522d4c4fb1fb30bb1833 370 Pfam PF07690 Major Facilitator Superfamily 12 334 4.6E-28 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_03605 bdf7de2759ce522d4c4fb1fb30bb1833 370 ProSitePatterns PS00216 Sugar transport proteins signature 1. 254 271 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_10885 dcd0f3300a4d570a0fd8dbaec0bee74d 364 Gene3D G3DSA:3.30.930.10 9 251 7.3E-46 T 31-10-2018 DFR86_10885 dcd0f3300a4d570a0fd8dbaec0bee74d 364 SUPERFAMILY SSF55681 1 247 4.31E-53 T 31-10-2018 DFR86_10885 dcd0f3300a4d570a0fd8dbaec0bee74d 364 Gene3D G3DSA:3.30.390.50 263 354 4.7E-19 T 31-10-2018 DFR86_10885 dcd0f3300a4d570a0fd8dbaec0bee74d 364 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 280 350 3.1E-6 T 31-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 DFR86_10885 dcd0f3300a4d570a0fd8dbaec0bee74d 364 SUPERFAMILY SSF82649 279 351 1.62E-5 T 31-10-2018 DFR86_01210 3d8a6732f20831a3625e9626e7b3d265 219 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 198 1.3E-29 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR86_01210 3d8a6732f20831a3625e9626e7b3d265 219 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 211 1.0E-36 T 31-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 DFR86_01210 3d8a6732f20831a3625e9626e7b3d265 219 Gene3D G3DSA:3.30.950.10 110 218 4.0E-6 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 DFR86_01210 3d8a6732f20831a3625e9626e7b3d265 219 SUPERFAMILY SSF53790 1 213 1.44E-35 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR86_01210 3d8a6732f20831a3625e9626e7b3d265 219 Gene3D G3DSA:3.40.1010.10 1 109 6.9E-20 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR86_08455 9e91bac87fa182e51e3e2a0cbfba977e 156 SUPERFAMILY SSF46785 11 71 7.14E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_08455 9e91bac87fa182e51e3e2a0cbfba977e 156 Gene3D G3DSA:3.30.70.920 65 156 1.6E-21 T 31-10-2018 DFR86_08455 9e91bac87fa182e51e3e2a0cbfba977e 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 3.4E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_08455 9e91bac87fa182e51e3e2a0cbfba977e 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 3.4E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_08455 9e91bac87fa182e51e3e2a0cbfba977e 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 3.4E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_08455 9e91bac87fa182e51e3e2a0cbfba977e 156 Gene3D G3DSA:1.10.10.10 1 64 2.0E-16 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_08455 9e91bac87fa182e51e3e2a0cbfba977e 156 SMART SM00344 11 117 3.3E-40 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR86_08455 9e91bac87fa182e51e3e2a0cbfba977e 156 Pfam PF01037 Lrp/AsnC ligand binding domain 78 146 4.5E-17 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR86_08455 9e91bac87fa182e51e3e2a0cbfba977e 156 SUPERFAMILY SSF54909 71 154 4.16E-17 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR86_08455 9e91bac87fa182e51e3e2a0cbfba977e 156 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 58 4.5E-12 T 31-10-2018 DFR86_02525 a9030b6a73643913bb265272ce009e62 164 Pfam PF00571 CBS domain 68 123 1.7E-13 T 31-10-2018 IPR000644 CBS domain DFR86_02525 a9030b6a73643913bb265272ce009e62 164 Pfam PF00571 CBS domain 5 59 1.4E-12 T 31-10-2018 IPR000644 CBS domain DFR86_02525 a9030b6a73643913bb265272ce009e62 164 SMART SM00116 75 123 6.9E-13 T 31-10-2018 IPR000644 CBS domain DFR86_02525 a9030b6a73643913bb265272ce009e62 164 SMART SM00116 12 60 8.0E-11 T 31-10-2018 IPR000644 CBS domain DFR86_02525 a9030b6a73643913bb265272ce009e62 164 SUPERFAMILY SSF54631 4 124 6.32E-33 T 31-10-2018 DFR86_02525 a9030b6a73643913bb265272ce009e62 164 Gene3D G3DSA:3.10.580.10 1 157 1.7E-40 T 31-10-2018 DFR86_10750 7c5e7ec99e32ed2da8ed1e6a2a308f3b 139 SUPERFAMILY SSF75169 5 135 1.56E-20 T 31-10-2018 IPR027396 DsrEFH-like DFR86_10750 7c5e7ec99e32ed2da8ed1e6a2a308f3b 139 Gene3D G3DSA:3.40.1260.10 1 139 2.4E-53 T 31-10-2018 IPR027396 DsrEFH-like DFR86_10750 7c5e7ec99e32ed2da8ed1e6a2a308f3b 139 Pfam PF13686 DsrE/DsrF/DrsH-like family 4 78 3.0E-17 T 31-10-2018 IPR032836 DsrE2-like family DFR86_07705 91fce4e46b0b313a06edaf2bf374753e 294 Hamap MF_02040 Iron-sulfur cluster carrier protein. 35 286 35.831 T 31-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein DFR86_07705 91fce4e46b0b313a06edaf2bf374753e 294 SUPERFAMILY SSF52540 42 289 7.27E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07705 91fce4e46b0b313a06edaf2bf374753e 294 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 39 286 6.5E-98 T 31-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 DFR86_07705 91fce4e46b0b313a06edaf2bf374753e 294 ProSitePatterns PS01215 Mrp family signature. 148 164 - T 31-10-2018 IPR000808 Mrp, conserved site GO:0005524 DFR86_07705 91fce4e46b0b313a06edaf2bf374753e 294 Gene3D G3DSA:3.40.50.300 28 279 8.9E-85 T 31-10-2018 DFR86_10815 70ea1d9f91e5f60841ba5a85dd4104d4 119 Pfam PF06348 Protein of unknown function (DUF1059) 3 58 3.9E-23 T 31-10-2018 IPR009409 Protein of unknown function DUF1059 DFR86_10815 70ea1d9f91e5f60841ba5a85dd4104d4 119 Pfam PF06348 Protein of unknown function (DUF1059) 62 117 1.0E-21 T 31-10-2018 IPR009409 Protein of unknown function DUF1059 DFR86_01870 380aef6e93387c905d26376825bdeecb 620 Gene3D G3DSA:3.40.920.10 1 213 1.0E-9 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR86_01870 380aef6e93387c905d26376825bdeecb 620 Gene3D G3DSA:3.40.50.920 499 609 5.7E-25 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR86_01870 380aef6e93387c905d26376825bdeecb 620 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 7 206 2.1E-28 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DFR86_01870 380aef6e93387c905d26376825bdeecb 620 Gene3D G3DSA:3.40.50.970 214 417 3.1E-68 T 31-10-2018 DFR86_01870 380aef6e93387c905d26376825bdeecb 620 SUPERFAMILY SSF52518 223 490 5.47E-56 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_01870 380aef6e93387c905d26376825bdeecb 620 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 508 599 1.2E-6 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II DFR86_01870 380aef6e93387c905d26376825bdeecb 620 SUPERFAMILY SSF53323 4 221 5.49E-11 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR86_01870 380aef6e93387c905d26376825bdeecb 620 SUPERFAMILY SSF52922 505 615 3.28E-17 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR86_01870 380aef6e93387c905d26376825bdeecb 620 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 236 482 1.1E-58 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DFR86_01870 380aef6e93387c905d26376825bdeecb 620 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 2 602 5.7E-176 T 31-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 2 842 1.6E-275 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 631 7.1E-177 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 Gene3D G3DSA:1.10.730.10 639 820 8.8E-35 T 31-10-2018 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 1 1045 12.637 T 31-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 Gene3D G3DSA:3.40.50.620 11 619 1.2E-218 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 Pfam PF08264 Anticodon-binding domain of tRNA 680 828 2.0E-26 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 SUPERFAMILY SSF47323 646 866 2.62E-47 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 SUPERFAMILY SSF47323 954 1039 5.23E-5 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 219 242 1.8E-26 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 514 527 1.8E-26 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 38 49 1.8E-26 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 1.8E-26 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 552 561 1.8E-26 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 SUPERFAMILY SSF52374 2 637 1.44E-122 T 31-10-2018 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 Gene3D G3DSA:3.90.740.10 195 397 1.2E-218 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 SUPERFAMILY SSF50677 198 393 1.26E-53 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR86_06760 6ac43847ff123edc8229ada5dc8b1045 1045 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 57 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_00545 cb09b0b26aa92abb9c4d4544c09c587d 758 SUPERFAMILY SSF54665 6 127 2.09E-28 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR86_00545 cb09b0b26aa92abb9c4d4544c09c587d 758 Gene3D G3DSA:3.30.365.10 12 268 4.3E-74 T 31-10-2018 DFR86_00545 cb09b0b26aa92abb9c4d4544c09c587d 758 SUPERFAMILY SSF56003 115 756 1.96E-137 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR86_00545 cb09b0b26aa92abb9c4d4544c09c587d 758 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 14 123 3.3E-15 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_00545 cb09b0b26aa92abb9c4d4544c09c587d 758 Gene3D G3DSA:3.30.365.10 124 345 4.3E-74 T 31-10-2018 DFR86_00545 cb09b0b26aa92abb9c4d4544c09c587d 758 Gene3D G3DSA:3.30.365.10 356 757 1.0E-88 T 31-10-2018 DFR86_00545 cb09b0b26aa92abb9c4d4544c09c587d 758 SMART SM01008 13 123 8.0E-29 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_00545 cb09b0b26aa92abb9c4d4544c09c587d 758 Gene3D G3DSA:3.90.1170.50 29 123 4.3E-74 T 31-10-2018 DFR86_00545 cb09b0b26aa92abb9c4d4544c09c587d 758 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 138 703 6.3E-127 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR86_00545 cb09b0b26aa92abb9c4d4544c09c587d 758 Gene3D G3DSA:3.30.365.10 438 621 1.0E-88 T 31-10-2018 DFR86_01480 58cce6ac70640091b72fe85a823c2473 366 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 46 354 1.5E-105 T 31-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 DFR86_01480 58cce6ac70640091b72fe85a823c2473 366 Gene3D G3DSA:1.20.120.420 15 165 5.5E-37 T 31-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 DFR86_01480 58cce6ac70640091b72fe85a823c2473 366 Gene3D G3DSA:3.40.50.10470 166 366 5.1E-62 T 31-10-2018 DFR86_01480 58cce6ac70640091b72fe85a823c2473 366 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 18 353 1.4E-109 T 31-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 DFR86_01480 58cce6ac70640091b72fe85a823c2473 366 SUPERFAMILY SSF100950 14 356 1.76E-105 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR86_01480 58cce6ac70640091b72fe85a823c2473 366 Pfam PF01008 Initiation factor 2 subunit family 59 354 1.5E-74 T 31-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 DFR86_01480 58cce6ac70640091b72fe85a823c2473 366 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 15 364 36.502 T 31-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 DFR86_04495 38f9f90386340ce0431548848629b993 368 PIRSF PIRSF038994 1 368 1.1E-107 T 31-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 DFR86_04495 38f9f90386340ce0431548848629b993 368 SUPERFAMILY SSF51556 47 337 8.16E-85 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_04495 38f9f90386340ce0431548848629b993 368 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 20 364 1.6E-79 T 31-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 DFR86_04495 38f9f90386340ce0431548848629b993 368 Gene3D G3DSA:3.20.20.140 47 338 8.2E-115 T 31-10-2018 DFR86_04495 38f9f90386340ce0431548848629b993 368 Pfam PF01979 Amidohydrolase family 43 367 1.2E-26 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_04495 38f9f90386340ce0431548848629b993 368 Gene3D G3DSA:2.30.40.10 8 365 8.2E-115 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04495 38f9f90386340ce0431548848629b993 368 SUPERFAMILY SSF51338 3 368 3.86E-14 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_09015 20b6edb3abd1ea786cfb9f4591dbc95a 144 Pfam PF01877 RNA binding 3 114 4.8E-17 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 DFR86_09015 20b6edb3abd1ea786cfb9f4591dbc95a 144 Gene3D G3DSA:3.30.1440.10 1 136 1.6E-43 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09015 20b6edb3abd1ea786cfb9f4591dbc95a 144 Hamap MF_01112 UPF0201 protein . 2 134 26.817 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 DFR86_09015 20b6edb3abd1ea786cfb9f4591dbc95a 144 SUPERFAMILY SSF55282 3 143 1.21E-43 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_11065 0e73dc16493393fd5e12ac23fe8021f2 74 Gene3D G3DSA:3.30.110.40 1 73 3.2E-5 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_11065 0e73dc16493393fd5e12ac23fe8021f2 74 Pfam PF01206 Sulfurtransferase TusA 3 72 1.1E-9 T 31-10-2018 IPR001455 TusA-like domain DFR86_11065 0e73dc16493393fd5e12ac23fe8021f2 74 SUPERFAMILY SSF64307 3 72 4.45E-9 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_05090 b5bf8ac9ca17b94b6680f26088dcb6f9 239 Gene3D G3DSA:1.20.120.1220 13 237 4.0E-12 T 31-10-2018 DFR86_05090 b5bf8ac9ca17b94b6680f26088dcb6f9 239 Gene3D G3DSA:3.30.1360.160 125 221 4.0E-12 T 31-10-2018 DFR86_05090 b5bf8ac9ca17b94b6680f26088dcb6f9 239 Pfam PF01478 Type IV leader peptidase family 11 97 4.9E-5 T 31-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 DFR86_05090 b5bf8ac9ca17b94b6680f26088dcb6f9 239 Pfam PF06847 Archaeal Peptidase A24 C-terminus Type II 147 237 1.6E-23 T 31-10-2018 IPR009655 Preflagellin peptidase, C-terminal DFR86_06335 b7663f41793096a7597b11393f66fb10 348 Gene3D G3DSA:3.30.470.20 95 342 2.9E-91 T 31-10-2018 DFR86_06335 b7663f41793096a7597b11393f66fb10 348 Gene3D G3DSA:3.30.1490.20 124 189 2.9E-91 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_06335 b7663f41793096a7597b11393f66fb10 348 Pfam PF06849 Protein of unknown function (DUF1246) 3 127 4.8E-48 T 31-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR86_06335 b7663f41793096a7597b11393f66fb10 348 Gene3D G3DSA:3.40.50.20 1 93 5.4E-32 T 31-10-2018 DFR86_06335 b7663f41793096a7597b11393f66fb10 348 SUPERFAMILY SSF56059 110 346 4.59E-74 T 31-10-2018 DFR86_06335 b7663f41793096a7597b11393f66fb10 348 SUPERFAMILY SSF52440 1 105 3.07E-38 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR86_06335 b7663f41793096a7597b11393f66fb10 348 PIRSF PIRSF004602 1 348 1.0E-143 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR86_06335 b7663f41793096a7597b11393f66fb10 348 Pfam PF06973 Domain of unknown function (DUF1297) 160 346 4.7E-78 T 31-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR86_10310 9782b7eccf13d645565049e5f6ea572b 480 Gene3D G3DSA:1.20.1720.10 7 240 8.0E-47 T 31-10-2018 DFR86_10310 9782b7eccf13d645565049e5f6ea572b 480 Gene3D G3DSA:1.20.1250.20 250 463 1.5E-18 T 31-10-2018 DFR86_10310 9782b7eccf13d645565049e5f6ea572b 480 SUPERFAMILY SSF103473 6 464 4.84E-73 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_10310 9782b7eccf13d645565049e5f6ea572b 480 Pfam PF07690 Major Facilitator Superfamily 12 279 2.5E-40 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_01430 c5b53372f562314af51392f69201bc86 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.3E-11 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_01430 c5b53372f562314af51392f69201bc86 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-11 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_01430 c5b53372f562314af51392f69201bc86 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.3E-11 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_01430 c5b53372f562314af51392f69201bc86 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 2.4E-62 T 31-10-2018 DFR86_01430 c5b53372f562314af51392f69201bc86 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.1E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_01430 c5b53372f562314af51392f69201bc86 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.1E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_01430 c5b53372f562314af51392f69201bc86 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.1E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_01430 c5b53372f562314af51392f69201bc86 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.1E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_01430 c5b53372f562314af51392f69201bc86 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.1E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_01430 c5b53372f562314af51392f69201bc86 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.1E-41 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_01430 c5b53372f562314af51392f69201bc86 256 SUPERFAMILY SSF51735 6 248 1.7E-79 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_01430 c5b53372f562314af51392f69201bc86 256 Gene3D G3DSA:3.40.50.720 2 254 1.7E-78 T 31-10-2018 DFR86_01675 c93c9efe65034ecd02adf5ce54b4e5e6 221 Pfam PF00881 Nitroreductase family 7 174 2.2E-25 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 DFR86_01675 c93c9efe65034ecd02adf5ce54b4e5e6 221 Gene3D G3DSA:3.40.109.10 1 177 1.4E-47 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 DFR86_01675 c93c9efe65034ecd02adf5ce54b4e5e6 221 SUPERFAMILY SSF55469 1 213 3.8E-49 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 DFR86_01675 c93c9efe65034ecd02adf5ce54b4e5e6 221 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 3 199 1.8E-73 T 31-10-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5523 DFR86_09290 1ed3e9e7d28bc63030ec5b248d524783 348 Hamap MF_01409 UPF0219 protein . 2 346 56.168 T 31-10-2018 IPR004656 Putative condensing enzyme FabH-related DFR86_09290 1ed3e9e7d28bc63030ec5b248d524783 348 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 3 346 5.8E-132 T 31-10-2018 IPR004656 Putative condensing enzyme FabH-related DFR86_09290 1ed3e9e7d28bc63030ec5b248d524783 348 SUPERFAMILY SSF53901 3 308 2.89E-44 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_09290 1ed3e9e7d28bc63030ec5b248d524783 348 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 222 301 2.5E-9 T 31-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 DFR86_09290 1ed3e9e7d28bc63030ec5b248d524783 348 Gene3D G3DSA:3.40.47.10 2 347 6.1E-74 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_09290 1ed3e9e7d28bc63030ec5b248d524783 348 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 147 9.2E-5 T 31-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 DFR86_00905 48618508321efc4903f9a5b22e77381f 128 SUPERFAMILY SSF53756 8 109 2.51E-15 T 31-10-2018 DFR86_00905 48618508321efc4903f9a5b22e77381f 128 Gene3D G3DSA:3.40.50.2000 5 118 2.1E-14 T 31-10-2018 DFR86_00905 48618508321efc4903f9a5b22e77381f 128 Pfam PF00534 Glycosyl transferases group 1 24 76 7.9E-11 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR86_02760 e76cdb3e6ec40543e01cb8338f2095c3 566 SUPERFAMILY SSF53756 17 553 5.23E-64 T 31-10-2018 DFR86_02760 e76cdb3e6ec40543e01cb8338f2095c3 566 Pfam PF00534 Glycosyl transferases group 1 344 496 1.2E-28 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR86_02760 e76cdb3e6ec40543e01cb8338f2095c3 566 Gene3D G3DSA:3.40.50.2000 308 531 3.5E-41 T 31-10-2018 DFR86_02760 e76cdb3e6ec40543e01cb8338f2095c3 566 Gene3D G3DSA:3.40.50.2000 15 301 2.9E-28 T 31-10-2018 DFR86_02760 e76cdb3e6ec40543e01cb8338f2095c3 566 Pfam PF08323 Starch synthase catalytic domain 16 255 2.6E-24 T 31-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 Gene3D G3DSA:3.30.479.30 50 181 3.0E-46 T 31-10-2018 DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 PRINTS PR00721 Stomatin signature 131 154 5.5E-56 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 PRINTS PR00721 Stomatin signature 155 173 5.5E-56 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 PRINTS PR00721 Stomatin signature 76 97 5.5E-56 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 PRINTS PR00721 Stomatin signature 174 195 5.5E-56 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 PRINTS PR00721 Stomatin signature 199 222 5.5E-56 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 PRINTS PR00721 Stomatin signature 29 51 5.5E-56 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 PRINTS PR00721 Stomatin signature 111 128 5.5E-56 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 Pfam PF01145 SPFH domain / Band 7 family 26 196 2.9E-39 T 31-10-2018 IPR001107 Band 7 domain DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 SMART SM00244 22 179 2.1E-59 T 31-10-2018 IPR001107 Band 7 domain DFR86_02275 aef39273d4cb2bd107bce59aef08f082 265 SUPERFAMILY SSF117892 53 186 2.22E-42 T 31-10-2018 IPR036013 Band 7/SPFH domain superfamily DFR86_02855 7e13b5c2266562eeaff713ec0cc922d5 431 Gene3D G3DSA:1.20.1740.10 23 430 4.4E-8 T 31-10-2018 DFR86_02855 7e13b5c2266562eeaff713ec0cc922d5 431 PIRSF PIRSF006060 4 429 1.2E-14 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 ProSitePatterns PS00163 Fumarate lyases signature. 269 278 - T 31-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 SUPERFAMILY SSF48557 4 440 4.08E-123 T 31-10-2018 IPR008948 L-Aspartase-like GO:0003824 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 Gene3D G3DSA:1.10.40.30 356 444 3.1E-20 T 31-10-2018 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 432 5.3E-138 T 31-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 Pfam PF10397 Adenylosuccinate lyase C-terminus 358 435 2.6E-15 T 31-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 Gene3D G3DSA:1.10.275.10 1 98 2.5E-28 T 31-10-2018 IPR024083 Fumarase/histidase, N-terminal DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 PRINTS PR00149 Fumarate lyase superfamily signature 94 112 1.3E-25 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 1.3E-25 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 PRINTS PR00149 Fumarate lyase superfamily signature 269 285 1.3E-25 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 PRINTS PR00149 Fumarate lyase superfamily signature 225 252 1.3E-25 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 Gene3D G3DSA:1.20.200.10 99 355 4.6E-90 T 31-10-2018 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 PRINTS PR00145 Argininosuccinate lyase family signature 269 285 2.2E-12 T 31-10-2018 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 PRINTS PR00145 Argininosuccinate lyase family signature 93 115 2.2E-12 T 31-10-2018 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 PRINTS PR00145 Argininosuccinate lyase family signature 134 154 2.2E-12 T 31-10-2018 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 PRINTS PR00145 Argininosuccinate lyase family signature 225 249 2.2E-12 T 31-10-2018 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 SMART SM00998 357 437 1.6E-22 T 31-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR86_06325 6d4eb76677a31dd9d3ca2747476e6d5b 454 Pfam PF00206 Lyase 13 291 6.4E-44 T 31-10-2018 IPR022761 Fumarate lyase, N-terminal DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 Gene3D G3DSA:1.10.8.60 452 527 6.6E-77 T 31-10-2018 DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 Gene3D G3DSA:3.40.50.300 14 188 1.5E-48 T 31-10-2018 DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 Gene3D G3DSA:1.10.8.60 189 272 4.6E-8 T 31-10-2018 DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 Gene3D G3DSA:3.40.50.300 283 540 6.6E-77 T 31-10-2018 DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 SUPERFAMILY SSF52540 283 541 9.42E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 ProSitePatterns PS00674 AAA-protein family signature. 157 175 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 SMART SM00382 52 189 3.1E-17 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 SMART SM00382 321 453 8.2E-22 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 ProSitePatterns PS00674 AAA-protein family signature. 421 439 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 Pfam PF09336 Vps4 C terminal oligomerisation domain 503 542 3.5E-5 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 325 450 7.0E-36 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 56 187 7.3E-38 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_01895 cf7ea125c8766a45f8866da80215ecad 544 SUPERFAMILY SSF52540 24 267 6.79E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 SUPERFAMILY SSF52540 457 749 8.99E-75 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Gene3D G3DSA:1.10.8.60 357 444 1.9E-32 T 31-10-2018 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Gene3D G3DSA:2.40.40.20 9 97 1.1E-30 T 31-10-2018 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Gene3D G3DSA:3.10.330.10 98 178 1.4E-6 T 31-10-2018 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 16 750 0.0 T 31-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 SUPERFAMILY SSF50692 10 99 1.49E-25 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Gene3D G3DSA:3.40.50.300 179 356 3.1E-71 T 31-10-2018 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 ProSitePatterns PS00674 AAA-protein family signature. 326 344 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 SMART SM01072 117 180 4.1E-14 T 31-10-2018 IPR004201 CDC48, domain 2 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Gene3D G3DSA:1.10.8.60 631 732 3.6E-103 T 31-10-2018 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 SUPERFAMILY SSF54585 101 191 2.29E-18 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 SMART SM00382 495 632 1.9E-21 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 SMART SM00382 222 358 9.5E-25 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 118 177 1.6E-14 T 31-10-2018 IPR004201 CDC48, domain 2 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 SUPERFAMILY SSF52540 183 451 1.4E-75 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 16 101 4.4E-32 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Gene3D G3DSA:3.40.50.300 457 747 3.6E-103 T 31-10-2018 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 ProSitePatterns PS00674 AAA-protein family signature. 600 618 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 SMART SM01073 15 101 3.9E-35 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Pfam PF09336 Vps4 C terminal oligomerisation domain 697 749 6.9E-7 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 226 356 3.4E-49 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_07150 7cb292bee8ef920e8e04f10aa511316f 766 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 499 629 4.1E-46 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_00005 d99f143deb362e15720cc03a56709c36 254 Pfam PF00176 SNF2 family N-terminal domain 54 200 4.2E-15 T 31-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 DFR86_00005 d99f143deb362e15720cc03a56709c36 254 SMART SM00487 30 219 7.8E-20 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_00005 d99f143deb362e15720cc03a56709c36 254 Gene3D G3DSA:3.40.50.10810 32 254 1.6E-45 T 31-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily DFR86_00005 d99f143deb362e15720cc03a56709c36 254 SUPERFAMILY SSF52540 15 208 5.89E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00370 f9d66a70c2b6db57d9a6a692104016aa 368 Pfam PF08402 TOBE domain 281 350 8.8E-11 T 31-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 DFR86_00370 f9d66a70c2b6db57d9a6a692104016aa 368 Gene3D G3DSA:2.40.50.140 284 343 2.7E-24 T 31-10-2018 DFR86_00370 f9d66a70c2b6db57d9a6a692104016aa 368 SUPERFAMILY SSF50331 242 358 2.67E-24 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal DFR86_00370 f9d66a70c2b6db57d9a6a692104016aa 368 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_00370 f9d66a70c2b6db57d9a6a692104016aa 368 SUPERFAMILY SSF52540 5 247 2.38E-77 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00370 f9d66a70c2b6db57d9a6a692104016aa 368 Gene3D G3DSA:3.40.50.300 2 242 4.4E-71 T 31-10-2018 DFR86_00370 f9d66a70c2b6db57d9a6a692104016aa 368 SMART SM00382 33 231 3.9E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_00370 f9d66a70c2b6db57d9a6a692104016aa 368 Gene3D G3DSA:2.40.50.100 244 355 2.7E-24 T 31-10-2018 DFR86_00370 f9d66a70c2b6db57d9a6a692104016aa 368 Pfam PF00005 ABC transporter 24 166 5.9E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_04405 6bb67b4ccfcf8d0e57ffe2d1b52a8a23 677 SUPERFAMILY SSF51445 155 526 1.43E-82 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR86_04405 6bb67b4ccfcf8d0e57ffe2d1b52a8a23 677 SUPERFAMILY SSF51011 528 602 1.29E-19 T 31-10-2018 DFR86_04405 6bb67b4ccfcf8d0e57ffe2d1b52a8a23 677 Pfam PF01055 Glycosyl hydrolases family 31 147 607 4.2E-135 T 31-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 DFR86_04405 6bb67b4ccfcf8d0e57ffe2d1b52a8a23 677 Gene3D G3DSA:2.60.40.1180 530 603 2.5E-27 T 31-10-2018 IPR013780 Glycosyl hydrolase, all-beta DFR86_04405 6bb67b4ccfcf8d0e57ffe2d1b52a8a23 677 Gene3D G3DSA:3.20.20.80 153 529 2.3E-147 T 31-10-2018 DFR86_04405 6bb67b4ccfcf8d0e57ffe2d1b52a8a23 677 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 315 322 - T 31-10-2018 IPR030458 Glycosyl hydrolases family 31, active site DFR86_04405 6bb67b4ccfcf8d0e57ffe2d1b52a8a23 677 Gene3D G3DSA:2.60.40.1760 2 151 9.2E-33 T 31-10-2018 DFR86_04405 6bb67b4ccfcf8d0e57ffe2d1b52a8a23 677 Pfam PF13802 Galactose mutarotase-like 61 126 1.3E-19 T 31-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain DFR86_04405 6bb67b4ccfcf8d0e57ffe2d1b52a8a23 677 SUPERFAMILY SSF74650 44 153 1.19E-24 T 31-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 DFR86_06200 39fed54b04b41b3c7b97da823d858cb1 102 Pfam PF00338 Ribosomal protein S10p/S20e 6 99 3.5E-27 T 31-10-2018 IPR027486 Ribosomal protein S10 domain DFR86_06200 39fed54b04b41b3c7b97da823d858cb1 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 28 43 - T 31-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06200 39fed54b04b41b3c7b97da823d858cb1 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 2 101 23.791 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06200 39fed54b04b41b3c7b97da823d858cb1 102 SMART SM01403 6 100 3.8E-37 T 31-10-2018 IPR027486 Ribosomal protein S10 domain DFR86_06200 39fed54b04b41b3c7b97da823d858cb1 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 4 101 4.0E-45 T 31-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06200 39fed54b04b41b3c7b97da823d858cb1 102 SUPERFAMILY SSF54999 4 101 2.62E-29 T 31-10-2018 IPR036838 Ribosomal protein S10 domain superfamily DFR86_06200 39fed54b04b41b3c7b97da823d858cb1 102 Gene3D G3DSA:3.30.70.600 2 101 3.0E-31 T 31-10-2018 IPR036838 Ribosomal protein S10 domain superfamily DFR86_06200 39fed54b04b41b3c7b97da823d858cb1 102 PRINTS PR00971 Ribosomal protein S10 family signature 39 54 1.4E-12 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06200 39fed54b04b41b3c7b97da823d858cb1 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.4E-12 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06200 39fed54b04b41b3c7b97da823d858cb1 102 PRINTS PR00971 Ribosomal protein S10 family signature 4 17 1.4E-12 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_03935 b540398233026f033bacc1371e57d8c4 179 Gene3D G3DSA:2.60.40.420 50 178 2.1E-15 T 31-10-2018 IPR008972 Cupredoxin DFR86_03935 b540398233026f033bacc1371e57d8c4 179 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 121 172 - T 31-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03935 b540398233026f033bacc1371e57d8c4 179 SUPERFAMILY SSF49503 56 179 1.19E-18 T 31-10-2018 IPR008972 Cupredoxin DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 Gene3D G3DSA:3.40.1380.20 307 439 2.5E-19 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 SUPERFAMILY SSF51621 5 314 6.98E-60 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 437 6.0E-94 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 Gene3D G3DSA:3.20.20.60 9 301 3.1E-78 T 31-10-2018 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 Pfam PF00224 Pyruvate kinase, barrel domain 6 306 1.6E-59 T 31-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 Gene3D G3DSA:2.40.33.10 63 145 3.1E-78 T 31-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 SUPERFAMILY SSF50800 72 141 5.58E-6 T 31-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 SUPERFAMILY SSF52935 317 430 3.01E-22 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 Pfam PF02887 Pyruvate kinase, alpha/beta domain 331 429 1.5E-16 T 31-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 PRINTS PR01050 Pyruvate kinase family signature 190 216 1.1E-46 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 PRINTS PR01050 Pyruvate kinase family signature 242 266 1.1E-46 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 PRINTS PR01050 Pyruvate kinase family signature 286 302 1.1E-46 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 PRINTS PR01050 Pyruvate kinase family signature 267 285 1.1E-46 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 PRINTS PR01050 Pyruvate kinase family signature 163 177 1.1E-46 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 PRINTS PR01050 Pyruvate kinase family signature 217 241 1.1E-46 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 PRINTS PR01050 Pyruvate kinase family signature 52 68 1.1E-46 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_04565 9bb2a25d31e917486f0cbf2d4ab7b1e1 440 ProSitePatterns PS00110 Pyruvate kinase active site signature. 188 200 - T 31-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_09140 aa5153b1ee7b65697be6c4d038b0db4b 299 PIRSF PIRSF012876 1 298 6.9E-102 T 31-10-2018 IPR014466 Predicted transcriptional regulator, AF1742 type DFR86_09140 aa5153b1ee7b65697be6c4d038b0db4b 299 Gene3D G3DSA:3.40.190.10 146 292 4.4E-9 T 31-10-2018 DFR86_09140 aa5153b1ee7b65697be6c4d038b0db4b 299 Pfam PF01047 MarR family 6 50 3.3E-9 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR86_09140 aa5153b1ee7b65697be6c4d038b0db4b 299 SUPERFAMILY SSF46785 6 69 1.16E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_09140 aa5153b1ee7b65697be6c4d038b0db4b 299 Gene3D G3DSA:1.10.10.10 1 63 4.4E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_09140 aa5153b1ee7b65697be6c4d038b0db4b 299 SUPERFAMILY SSF53850 63 236 2.12E-14 T 31-10-2018 DFR86_03540 8e2286c31194bfb45052468a3611118b 368 SUPERFAMILY SSF103473 7 367 6.28E-28 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_03540 8e2286c31194bfb45052468a3611118b 368 Pfam PF07690 Major Facilitator Superfamily 9 307 1.8E-15 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_03540 8e2286c31194bfb45052468a3611118b 368 Gene3D G3DSA:1.20.1250.20 1 189 5.7E-14 T 31-10-2018 DFR86_03540 8e2286c31194bfb45052468a3611118b 368 Gene3D G3DSA:1.20.1250.20 190 368 8.9E-8 T 31-10-2018 DFR86_05790 8803a6866523336b663338ebc29be563 132 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 129 22.273 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DFR86_05790 8803a6866523336b663338ebc29be563 132 Pfam PF00411 Ribosomal protein S11 10 128 1.3E-47 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DFR86_05790 8803a6866523336b663338ebc29be563 132 SUPERFAMILY SSF53137 5 130 3.34E-34 T 31-10-2018 DFR86_05790 8803a6866523336b663338ebc29be563 132 PIRSF PIRSF002131 1 131 1.2E-32 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DFR86_05790 8803a6866523336b663338ebc29be563 132 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 31-10-2018 IPR018102 Ribosomal S11, conserved site DFR86_05790 8803a6866523336b663338ebc29be563 132 Gene3D G3DSA:3.30.420.80 1 132 1.8E-57 T 31-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_05790 8803a6866523336b663338ebc29be563 132 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 8 124 2.2E-60 T 31-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06945 f8ca593686756c6245cd88c4d927dc42 299 PIRSF PIRSF009433 1 299 2.0E-88 T 31-10-2018 IPR009927 Protein of unknown function DUF1464 DFR86_06945 f8ca593686756c6245cd88c4d927dc42 299 Pfam PF07318 Protein of unknown function (DUF1464) 5 286 1.8E-97 T 31-10-2018 IPR009927 Protein of unknown function DUF1464 DFR86_02240 ee3dc0bfcfd9c3325c0356e6fac6e734 350 Gene3D G3DSA:3.20.20.70 2 329 4.2E-43 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_02240 ee3dc0bfcfd9c3325c0356e6fac6e734 350 SUPERFAMILY SSF102114 5 288 1.01E-37 T 31-10-2018 DFR86_02240 ee3dc0bfcfd9c3325c0356e6fac6e734 350 Pfam PF04055 Radical SAM superfamily 8 143 7.5E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_02240 ee3dc0bfcfd9c3325c0356e6fac6e734 350 TIGRFAM TIGR04084 rSAM_AF0577: putative peptide-modifying radical SAM enzyme, AF0577 family 5 350 8.5E-177 T 31-10-2018 IPR023819 Peptide-modifying radical SAM enzyme putative, AF0577 DFR86_02240 ee3dc0bfcfd9c3325c0356e6fac6e734 350 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 228 295 5.7E-9 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR86_02240 ee3dc0bfcfd9c3325c0356e6fac6e734 350 Pfam PF13353 4Fe-4S single cluster domain 5 118 3.5E-8 T 31-10-2018 DFR86_05000 909b650cd2d86571b86554565e4632b9 159 SMART SM00855 3 117 4.5E-5 T 31-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 DFR86_05000 909b650cd2d86571b86554565e4632b9 159 PIRSF PIRSF000709 3 87 8.8E-8 T 31-10-2018 DFR86_05000 909b650cd2d86571b86554565e4632b9 159 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 83 2.3E-12 T 31-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 DFR86_05000 909b650cd2d86571b86554565e4632b9 159 SUPERFAMILY SSF53254 1 142 3.67E-27 T 31-10-2018 IPR029033 Histidine phosphatase superfamily DFR86_05000 909b650cd2d86571b86554565e4632b9 159 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 3 147 7.5E-29 T 31-10-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0101006 DFR86_05000 909b650cd2d86571b86554565e4632b9 159 Gene3D G3DSA:3.40.50.1240 2 159 1.6E-34 T 31-10-2018 IPR029033 Histidine phosphatase superfamily DFR86_06835 14df5f019e45fb5247170319ccf3efc0 166 SUPERFAMILY SSF55282 1 161 8.01E-56 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06835 14df5f019e45fb5247170319ccf3efc0 166 Pfam PF00281 Ribosomal protein L5 1 52 1.1E-18 T 31-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06835 14df5f019e45fb5247170319ccf3efc0 166 Gene3D G3DSA:3.30.1440.10 1 166 3.0E-66 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06835 14df5f019e45fb5247170319ccf3efc0 166 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 1 165 38.42 T 31-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06835 14df5f019e45fb5247170319ccf3efc0 166 Pfam PF00673 ribosomal L5P family C-terminus 57 155 3.7E-25 T 31-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06835 14df5f019e45fb5247170319ccf3efc0 166 ProSitePatterns PS00358 Ribosomal protein L5 signature. 29 45 - T 31-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06835 14df5f019e45fb5247170319ccf3efc0 166 PIRSF PIRSF002161 1 164 5.4E-51 T 31-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_03050 905fc7faa4cb5af31f52be945c4414b7 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 35 55 2.7E-9 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 DFR86_03050 905fc7faa4cb5af31f52be945c4414b7 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 57 73 2.7E-9 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 DFR86_03050 905fc7faa4cb5af31f52be945c4414b7 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 78 94 2.7E-9 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 DFR86_03050 905fc7faa4cb5af31f52be945c4414b7 257 Pfam PF00459 Inositol monophosphatase family 21 235 3.7E-24 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 DFR86_03050 905fc7faa4cb5af31f52be945c4414b7 257 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 79 91 - T 31-10-2018 IPR020583 Inositol monophosphatase, metal-binding site DFR86_03050 905fc7faa4cb5af31f52be945c4414b7 257 Gene3D G3DSA:3.30.540.10 1 138 4.0E-25 T 31-10-2018 DFR86_03050 905fc7faa4cb5af31f52be945c4414b7 257 SUPERFAMILY SSF56655 2 249 1.83E-40 T 31-10-2018 DFR86_03050 905fc7faa4cb5af31f52be945c4414b7 257 Gene3D G3DSA:3.40.190.80 142 257 3.5E-17 T 31-10-2018 DFR86_05745 36ddcb0d0da2eb83e6f5a48fea6cc552 228 Gene3D G3DSA:3.40.1160.10 12 226 1.7E-42 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR86_05745 36ddcb0d0da2eb83e6f5a48fea6cc552 228 SUPERFAMILY SSF53633 14 224 1.83E-23 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR86_05745 36ddcb0d0da2eb83e6f5a48fea6cc552 228 Pfam PF00696 Amino acid kinase family 15 200 6.3E-23 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 SUPERFAMILY SSF56059 668 924 7.41E-80 T 31-10-2018 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 Gene3D G3DSA:1.10.1030.10 404 546 5.1E-39 T 31-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 831 838 - T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 Gene3D G3DSA:3.30.470.20 117 398 1.3E-108 T 31-10-2018 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 SUPERFAMILY SSF48108 391 547 8.76E-43 T 31-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 Gene3D G3DSA:3.30.1490.20 681 749 5.8E-86 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 126 330 1.5E-65 T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 858 8.6E-26 T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 7.1E-32 T 31-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 Gene3D G3DSA:3.40.50.20 1 113 1.8E-44 T 31-10-2018 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 Gene3D G3DSA:3.30.470.20 662 921 5.8E-86 T 31-10-2018 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 165 177 1.3E-57 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 236 253 1.3E-57 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 201 220 1.3E-57 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 293 322 1.3E-57 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 16 30 1.3E-57 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 375 393 1.3E-57 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 45 55 1.3E-57 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 Gene3D G3DSA:3.40.50.20 549 657 2.9E-27 T 31-10-2018 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1027 0.0 T 31-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 SUPERFAMILY SSF52440 552 670 2.3E-32 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 SUPERFAMILY SSF56059 126 396 4.55E-96 T 31-10-2018 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 2 1045 13.564 T 31-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 SUPERFAMILY SSF52440 3 123 9.64E-42 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR86_08285 f5ec32fb14e3fea267adf182687cb52c 1049 SMART SM01096 419 540 9.2E-48 T 31-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_02950 0dcee5489bb74b9cbac2400ec29abd19 378 Gene3D G3DSA:2.30.40.10 302 360 1.3E-7 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_02950 0dcee5489bb74b9cbac2400ec29abd19 378 Gene3D G3DSA:3.20.20.140 273 292 1.3E-7 T 31-10-2018 DFR86_02950 0dcee5489bb74b9cbac2400ec29abd19 378 SUPERFAMILY SSF51338 3 365 1.03E-9 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_02950 0dcee5489bb74b9cbac2400ec29abd19 378 Gene3D G3DSA:3.20.20.140 57 192 6.0E-10 T 31-10-2018 DFR86_02950 0dcee5489bb74b9cbac2400ec29abd19 378 SUPERFAMILY SSF51556 84 295 2.77E-7 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_02950 0dcee5489bb74b9cbac2400ec29abd19 378 Gene3D G3DSA:2.30.40.10 22 56 6.0E-10 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04875 ba0ef58083b815f93719527a49760a72 233 Pfam PF11485 Protein of unknown function (DUF3211) 1 132 9.2E-6 T 31-10-2018 IPR021578 Protein of unknown function DUF3211 DFR86_04875 ba0ef58083b815f93719527a49760a72 233 SUPERFAMILY SSF55961 1 122 8.25E-9 T 31-10-2018 DFR86_06130 ac9a26d3b0c015887417fba3e2e1d56b 152 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 6 140 8.4E-41 T 31-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_06130 ac9a26d3b0c015887417fba3e2e1d56b 152 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 1 141 23.321 T 31-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_06130 ac9a26d3b0c015887417fba3e2e1d56b 152 Gene3D G3DSA:3.40.50.960 1 142 4.1E-35 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_06130 ac9a26d3b0c015887417fba3e2e1d56b 152 SUPERFAMILY SSF52121 4 141 6.15E-41 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_06130 ac9a26d3b0c015887417fba3e2e1d56b 152 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 6 137 1.9E-36 T 31-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_04390 2cd95465fe8e8081742f15b48e2f3f88 664 Pfam PF13193 AMP-binding enzyme C-terminal domain 540 618 7.3E-27 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR86_04390 2cd95465fe8e8081742f15b48e2f3f88 664 Gene3D G3DSA:3.30.300.30 527 656 1.6E-26 T 31-10-2018 DFR86_04390 2cd95465fe8e8081742f15b48e2f3f88 664 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 27 650 3.8E-282 T 31-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 DFR86_04390 2cd95465fe8e8081742f15b48e2f3f88 664 Gene3D G3DSA:3.40.50.12780 54 525 5.6E-99 T 31-10-2018 DFR86_04390 2cd95465fe8e8081742f15b48e2f3f88 664 SUPERFAMILY SSF56801 17 650 1.96E-167 T 31-10-2018 DFR86_04390 2cd95465fe8e8081742f15b48e2f3f88 664 ProSitePatterns PS00455 Putative AMP-binding domain signature. 268 279 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR86_04390 2cd95465fe8e8081742f15b48e2f3f88 664 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 28 80 1.3E-17 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR86_04390 2cd95465fe8e8081742f15b48e2f3f88 664 Pfam PF00501 AMP-binding enzyme 92 531 2.4E-89 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR86_04340 cc7039c7337fdcc1a317d33337ac6d18 171 Pfam PF01730 UreF 28 137 3.8E-9 T 31-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 DFR86_04340 cc7039c7337fdcc1a317d33337ac6d18 171 Gene3D G3DSA:1.10.4190.10 2 148 2.8E-12 T 31-10-2018 IPR038277 UreF domain superfamily DFR86_10615 7be773a0cd995d3352d04f32a7762bfe 446 SUPERFAMILY SSF53448 48 334 3.73E-30 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_10615 7be773a0cd995d3352d04f32a7762bfe 446 Gene3D G3DSA:3.90.550.10 35 299 2.2E-18 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_10615 7be773a0cd995d3352d04f32a7762bfe 446 Pfam PF13641 Glycosyltransferase like family 2 49 268 4.1E-16 T 31-10-2018 DFR86_06850 56dfdbf855e3a0d0c93bc840bfdf63d3 180 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 7 176 1.7E-64 T 31-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 DFR86_06850 56dfdbf855e3a0d0c93bc840bfdf63d3 180 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 155 176 - T 31-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06850 56dfdbf855e3a0d0c93bc840bfdf63d3 180 PIRSF PIRSF002162 1 178 1.3E-31 T 31-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06850 56dfdbf855e3a0d0c93bc840bfdf63d3 180 Gene3D G3DSA:3.90.930.12 5 84 3.6E-23 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06850 56dfdbf855e3a0d0c93bc840bfdf63d3 180 Gene3D G3DSA:3.90.930.12 85 179 7.1E-32 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06850 56dfdbf855e3a0d0c93bc840bfdf63d3 180 SUPERFAMILY SSF56053 85 176 1.01E-25 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06850 56dfdbf855e3a0d0c93bc840bfdf63d3 180 Pfam PF00347 Ribosomal protein L6 96 170 6.1E-12 T 31-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06850 56dfdbf855e3a0d0c93bc840bfdf63d3 180 Pfam PF00347 Ribosomal protein L6 11 84 1.5E-12 T 31-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06850 56dfdbf855e3a0d0c93bc840bfdf63d3 180 SUPERFAMILY SSF56053 5 84 2.21E-19 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06850 56dfdbf855e3a0d0c93bc840bfdf63d3 180 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 1 177 33.47 T 31-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 DFR86_04065 ddbafcf25c7d5d5b3bc57960a12faf95 228 Gene3D G3DSA:3.30.70.20 21 215 7.4E-52 T 31-10-2018 DFR86_04065 ddbafcf25c7d5d5b3bc57960a12faf95 228 SUPERFAMILY SSF54862 20 215 1.88E-54 T 31-10-2018 DFR86_04065 ddbafcf25c7d5d5b3bc57960a12faf95 228 Gene3D G3DSA:3.30.70.20 83 152 7.4E-52 T 31-10-2018 DFR86_04065 ddbafcf25c7d5d5b3bc57960a12faf95 228 Pfam PF13247 4Fe-4S dicluster domain 71 126 7.1E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_04065 ddbafcf25c7d5d5b3bc57960a12faf95 228 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 109 120 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_11150 4f7558b491371d8f0c9339d594f6132a 286 SUPERFAMILY SSF56176 1 172 5.07E-49 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_11150 4f7558b491371d8f0c9339d594f6132a 286 SUPERFAMILY SSF55447 176 284 1.83E-23 T 31-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily DFR86_11150 4f7558b491371d8f0c9339d594f6132a 286 SMART SM01092 178 283 7.0E-22 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR86_11150 4f7558b491371d8f0c9339d594f6132a 286 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 179 283 4.1E-18 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR86_11150 4f7558b491371d8f0c9339d594f6132a 286 Gene3D G3DSA:3.30.390.50 177 285 1.1E-24 T 31-10-2018 DFR86_11150 4f7558b491371d8f0c9339d594f6132a 286 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 172 7.6E-46 T 31-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DFR86_11150 4f7558b491371d8f0c9339d594f6132a 286 Gene3D G3DSA:3.30.465.10 56 172 3.5E-39 T 31-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 DFR86_11150 4f7558b491371d8f0c9339d594f6132a 286 Gene3D G3DSA:3.30.43.10 1 52 5.1E-18 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR86_04160 5e9be4ba3ac7760e36c34b507c57e418 402 SUPERFAMILY SSF103473 2 397 9.81E-50 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_04160 5e9be4ba3ac7760e36c34b507c57e418 402 Gene3D G3DSA:1.20.1250.20 1 401 4.2E-49 T 31-10-2018 DFR86_04160 5e9be4ba3ac7760e36c34b507c57e418 402 Pfam PF07690 Major Facilitator Superfamily 10 344 1.4E-22 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_01680 c421264300e7774fefbdecfe1b31357b 341 Pfam PF02769 AIR synthase related protein, C-terminal domain 156 307 1.5E-18 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR86_01680 c421264300e7774fefbdecfe1b31357b 341 Pfam PF00586 AIR synthase related protein, N-terminal domain 46 140 4.6E-9 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR86_01680 c421264300e7774fefbdecfe1b31357b 341 Gene3D G3DSA:3.30.1330.10 1 144 1.6E-18 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_01680 c421264300e7774fefbdecfe1b31357b 341 PIRSF PIRSF005644 1 333 7.5E-99 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE DFR86_01680 c421264300e7774fefbdecfe1b31357b 341 SUPERFAMILY SSF55326 15 143 7.33E-19 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_01680 c421264300e7774fefbdecfe1b31357b 341 SUPERFAMILY SSF56042 153 306 1.79E-26 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_01680 c421264300e7774fefbdecfe1b31357b 341 Gene3D G3DSA:3.90.650.10 148 332 3.6E-34 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_07975 be65a88d4f2ea8499d319b16115cb0a1 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 43 59 5.0E-7 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR86_07975 be65a88d4f2ea8499d319b16115cb0a1 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 75 5.0E-7 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR86_07975 be65a88d4f2ea8499d319b16115cb0a1 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 95 5.0E-7 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR86_07975 be65a88d4f2ea8499d319b16115cb0a1 136 Gene3D G3DSA:1.10.10.10 2 134 3.8E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_07975 be65a88d4f2ea8499d319b16115cb0a1 136 SUPERFAMILY SSF46785 4 113 6.3E-22 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_07975 be65a88d4f2ea8499d319b16115cb0a1 136 Pfam PF01047 MarR family 27 84 3.9E-11 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR86_07975 be65a88d4f2ea8499d319b16115cb0a1 136 SMART SM00347 20 115 2.6E-13 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR86_05540 5ec4cde228061d1ad94b5398e9b9da21 242 Pfam PF01026 TatD related DNase 3 239 8.0E-49 T 31-10-2018 IPR001130 TatD family GO:0016788 DFR86_05540 5ec4cde228061d1ad94b5398e9b9da21 242 PIRSF PIRSF005902 1 242 5.1E-55 T 31-10-2018 IPR001130 TatD family GO:0016788 DFR86_05540 5ec4cde228061d1ad94b5398e9b9da21 242 Gene3D G3DSA:3.20.20.140 1 241 3.6E-61 T 31-10-2018 DFR86_05540 5ec4cde228061d1ad94b5398e9b9da21 242 SUPERFAMILY SSF51556 2 240 2.54E-52 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_08235 75768db29a16011e72b8ac62fbb49037 351 PIRSF PIRSF004869 1 311 1.3E-84 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted DFR86_08235 75768db29a16011e72b8ac62fbb49037 351 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 9 349 8.0E-93 T 31-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme DFR86_08235 75768db29a16011e72b8ac62fbb49037 351 Pfam PF04055 Radical SAM superfamily 79 229 1.7E-18 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_08235 75768db29a16011e72b8ac62fbb49037 351 SMART SM00729 72 276 0.0063 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_08235 75768db29a16011e72b8ac62fbb49037 351 Gene3D G3DSA:3.20.20.70 56 284 1.2E-27 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_08235 75768db29a16011e72b8ac62fbb49037 351 SUPERFAMILY SSF102114 50 313 6.15E-32 T 31-10-2018 DFR86_05850 e3878b4264781326e3332dcd88b31bac 187 SUPERFAMILY SSF55729 5 178 7.77E-48 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR86_05850 e3878b4264781326e3332dcd88b31bac 187 Gene3D G3DSA:3.40.630.30 2 146 3.3E-36 T 31-10-2018 DFR86_05850 e3878b4264781326e3332dcd88b31bac 187 Pfam PF06557 Protein of unknown function (DUF1122) 11 166 2.4E-50 T 31-10-2018 IPR008304 Uncharacterised conserved protein UCP017998 DFR86_04045 b381a3a90c270a8b8bd35ab6ec7dc63f 232 Pfam PF01209 ubiE/COQ5 methyltransferase family 5 203 2.9E-21 T 31-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 DFR86_04045 b381a3a90c270a8b8bd35ab6ec7dc63f 232 SUPERFAMILY SSF53335 7 225 5.4E-20 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_04045 b381a3a90c270a8b8bd35ab6ec7dc63f 232 Gene3D G3DSA:3.40.50.150 17 210 5.2E-25 T 31-10-2018 DFR86_04045 b381a3a90c270a8b8bd35ab6ec7dc63f 232 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 21 36 - T 31-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 DFR86_04220 8fd070472e9bd81bb559bff8e97e611e 403 Pfam PF01979 Amidohydrolase family 41 389 3.4E-20 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_04220 8fd070472e9bd81bb559bff8e97e611e 403 SUPERFAMILY SSF51556 46 362 2.38E-60 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_04220 8fd070472e9bd81bb559bff8e97e611e 403 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 46 54 - T 31-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 DFR86_04220 8fd070472e9bd81bb559bff8e97e611e 403 SUPERFAMILY SSF51338 12 394 3.1E-5 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04220 8fd070472e9bd81bb559bff8e97e611e 403 Gene3D G3DSA:2.30.40.10 13 391 4.5E-99 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04220 8fd070472e9bd81bb559bff8e97e611e 403 Gene3D G3DSA:3.20.20.140 46 351 4.5E-99 T 31-10-2018 DFR86_02320 f2807ace93aa74849252422df95bdc0f 221 SUPERFAMILY SSF55961 8 122 6.59E-5 T 31-10-2018 DFR86_02915 79252919eae9c09113953a3e88499b2e 353 SUPERFAMILY SSF100879 240 343 1.53E-22 T 31-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 DFR86_02915 79252919eae9c09113953a3e88499b2e 353 Pfam PF11798 IMS family HHH motif 169 200 2.2E-6 T 31-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 DFR86_02915 79252919eae9c09113953a3e88499b2e 353 Gene3D G3DSA:1.10.150.20 168 234 9.0E-22 T 31-10-2018 DFR86_02915 79252919eae9c09113953a3e88499b2e 353 Gene3D G3DSA:2.30.40.20 11 74 4.9E-27 T 31-10-2018 DFR86_02915 79252919eae9c09113953a3e88499b2e 353 SUPERFAMILY SSF56672 3 240 2.22E-67 T 31-10-2018 DFR86_02915 79252919eae9c09113953a3e88499b2e 353 Gene3D G3DSA:3.30.1490.100 240 342 4.8E-25 T 31-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 DFR86_02915 79252919eae9c09113953a3e88499b2e 353 Gene3D G3DSA:3.30.70.270 75 167 4.0E-30 T 31-10-2018 DFR86_02915 79252919eae9c09113953a3e88499b2e 353 Pfam PF00817 impB/mucB/samB family 6 156 4.9E-44 T 31-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 DFR86_02465 b6b5d35913d043e3c0a7b5b40ecb59e7 381 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 381 24.94 T 31-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 DFR86_02465 b6b5d35913d043e3c0a7b5b40ecb59e7 381 Gene3D G3DSA:3.60.21.10 1 253 6.0E-59 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR86_02465 b6b5d35913d043e3c0a7b5b40ecb59e7 381 Pfam PF00149 Calcineurin-like phosphoesterase 1 196 1.3E-16 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR86_02465 b6b5d35913d043e3c0a7b5b40ecb59e7 381 SUPERFAMILY SSF56300 1 305 2.59E-53 T 31-10-2018 DFR86_07200 20d1e4b5131da0682e0e9f2165b44838 540 Gene3D G3DSA:3.40.50.1220 197 363 3.3E-40 T 31-10-2018 DFR86_07200 20d1e4b5131da0682e0e9f2165b44838 540 Gene3D G3DSA:3.40.50.970 7 195 3.3E-18 T 31-10-2018 DFR86_07200 20d1e4b5131da0682e0e9f2165b44838 540 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 338 3.1E-32 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DFR86_07200 20d1e4b5131da0682e0e9f2165b44838 540 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 181 2.6E-17 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR86_07200 20d1e4b5131da0682e0e9f2165b44838 540 SUPERFAMILY SSF52518 8 197 3.35E-15 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_07200 20d1e4b5131da0682e0e9f2165b44838 540 SUPERFAMILY SSF52467 196 385 5.73E-39 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_08485 b806eecda88161af418f8a1c7aca8d7d 131 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 60 109 1.0E-12 T 31-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 DFR86_08485 b806eecda88161af418f8a1c7aca8d7d 131 SUPERFAMILY SSF141734 14 114 1.96E-40 T 31-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 DFR86_08485 b806eecda88161af418f8a1c7aca8d7d 131 Gene3D G3DSA:3.10.20.400 3 100 7.4E-33 T 31-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 DFR86_08485 b806eecda88161af418f8a1c7aca8d7d 131 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 36 109 2.6E-31 T 31-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 DFR86_07120 38ef50bdcad468ce957b80f2b14154d7 426 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 9 424 87.457 T 31-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 DFR86_07120 38ef50bdcad468ce957b80f2b14154d7 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_07120 38ef50bdcad468ce957b80f2b14154d7 426 SUPERFAMILY SSF53383 9 420 1.85E-111 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_07120 38ef50bdcad468ce957b80f2b14154d7 426 Gene3D G3DSA:3.40.640.10 73 319 8.8E-156 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_07120 38ef50bdcad468ce957b80f2b14154d7 426 Pfam PF00202 Aminotransferase class-III 33 397 3.1E-72 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_07120 38ef50bdcad468ce957b80f2b14154d7 426 Gene3D G3DSA:3.90.1150.10 14 414 8.8E-156 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_07120 38ef50bdcad468ce957b80f2b14154d7 426 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 10 418 1.1E-167 T 31-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 DFR86_04820 ab706d0c389dbf80848af34a26d68654 295 Gene3D G3DSA:3.40.640.10 23 295 1.9E-17 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_04820 ab706d0c389dbf80848af34a26d68654 295 SUPERFAMILY SSF53383 5 294 1.44E-23 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_04820 ab706d0c389dbf80848af34a26d68654 295 Pfam PF00155 Aminotransferase class I and II 120 192 3.4E-5 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR86_08405 0e7c6cf4a932af3fc39b32b4d2e010f4 216 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 53 66 - T 31-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08405 0e7c6cf4a932af3fc39b32b4d2e010f4 216 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 1 210 32.946 T 31-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08405 0e7c6cf4a932af3fc39b32b4d2e010f4 216 SMART SM00934 1 200 7.1E-27 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08405 0e7c6cf4a932af3fc39b32b4d2e010f4 216 SUPERFAMILY SSF51366 1 208 5.97E-40 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR86_08405 0e7c6cf4a932af3fc39b32b4d2e010f4 216 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 11 199 2.8E-20 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08405 0e7c6cf4a932af3fc39b32b4d2e010f4 216 Gene3D G3DSA:3.20.20.70 1 216 4.0E-51 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_03010 6d5d123b37fa2947099248f069e95d6b 170 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 12 160 5.0E-30 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 DFR86_03010 6d5d123b37fa2947099248f069e95d6b 170 Gene3D G3DSA:2.60.120.1040 58 170 3.0E-16 T 31-10-2018 DFR86_03010 6d5d123b37fa2947099248f069e95d6b 170 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 13 161 9.6E-46 T 31-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 DFR86_03010 6d5d123b37fa2947099248f069e95d6b 170 SMART SM00709 11 156 8.0E-32 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 DFR86_03010 6d5d123b37fa2947099248f069e95d6b 170 Pfam PF03367 ZPR1 zinc-finger domain 12 154 4.1E-29 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 SUPERFAMILY SSF143437 2 167 3.31E-40 T 31-10-2018 DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 SMART SM00450 376 466 3.2E-6 T 31-10-2018 IPR001763 Rhodanese-like domain DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 SUPERFAMILY SSF52402 169 361 1.68E-34 T 31-10-2018 DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 169 360 2.5E-53 T 31-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 Gene3D G3DSA:3.40.250.10 383 463 2.3E-14 T 31-10-2018 IPR036873 Rhodanese-like domain superfamily DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 Pfam PF00581 Rhodanese-like domain 390 458 4.3E-9 T 31-10-2018 IPR001763 Rhodanese-like domain DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 Gene3D G3DSA:3.40.50.620 169 377 1.1E-51 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 466 122.577 T 31-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 SMART SM00981 72 159 1.1E-20 T 31-10-2018 IPR004114 THUMP domain GO:0003723 DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 Pfam PF02926 THUMP domain 29 156 2.1E-21 T 31-10-2018 IPR004114 THUMP domain GO:0003723 DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 SUPERFAMILY SSF52821 384 459 9.69E-16 T 31-10-2018 IPR036873 Rhodanese-like domain superfamily DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 Gene3D G3DSA:3.30.2130.30 1 168 2.0E-37 T 31-10-2018 DFR86_01915 d27e1bdea3f0fb24f64602d609a313ae 466 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 361 1.9E-88 T 31-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 SUPERFAMILY SSF52935 301 443 4.45E-27 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 443 1.3E-120 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 Gene3D G3DSA:3.40.1380.20 314 439 8.4E-124 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 Pfam PF00224 Pyruvate kinase, barrel domain 1 319 4.8E-81 T 31-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 PRINTS PR01050 Pyruvate kinase family signature 168 182 2.1E-54 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 PRINTS PR01050 Pyruvate kinase family signature 247 271 2.1E-54 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 PRINTS PR01050 Pyruvate kinase family signature 291 307 2.1E-54 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 PRINTS PR01050 Pyruvate kinase family signature 51 67 2.1E-54 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 PRINTS PR01050 Pyruvate kinase family signature 195 221 2.1E-54 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 PRINTS PR01050 Pyruvate kinase family signature 222 246 2.1E-54 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 PRINTS PR01050 Pyruvate kinase family signature 272 290 2.1E-54 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 SUPERFAMILY SSF50800 62 148 1.52E-16 T 31-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 Pfam PF02887 Pyruvate kinase, alpha/beta domain 329 441 2.3E-20 T 31-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 Gene3D G3DSA:2.40.33.10 62 150 8.4E-124 T 31-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 Gene3D G3DSA:3.20.20.60 2 313 8.4E-124 T 31-10-2018 DFR86_02790 377b78e2998fdf190e645aa6299bebd1 443 SUPERFAMILY SSF51621 1 317 2.06E-74 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR86_11245 d9a24062d14e96760248fac509a13cad 428 Gene3D G3DSA:3.50.50.60 173 284 1.4E-12 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_11245 d9a24062d14e96760248fac509a13cad 428 Gene3D G3DSA:3.50.50.60 1 59 2.5E-12 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_11245 d9a24062d14e96760248fac509a13cad 428 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 6.3E-7 T 31-10-2018 DFR86_11245 d9a24062d14e96760248fac509a13cad 428 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 6.3E-7 T 31-10-2018 DFR86_11245 d9a24062d14e96760248fac509a13cad 428 SUPERFAMILY SSF51905 1 423 3.89E-38 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_11245 d9a24062d14e96760248fac509a13cad 428 Pfam PF01593 Flavin containing amine oxidoreductase 12 261 4.7E-13 T 31-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 DFR86_00360 aa2e0b153516cf1aa2b5c6a8c6bbb231 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 289 1.1E-13 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_00360 aa2e0b153516cf1aa2b5c6a8c6bbb231 292 Gene3D G3DSA:1.10.3720.10 47 288 2.5E-61 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_00360 aa2e0b153516cf1aa2b5c6a8c6bbb231 292 SUPERFAMILY SSF161098 51 279 1.7E-55 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_01075 bb02e35821c17e3cecd714b7913bc79d 295 SUPERFAMILY SSF161098 98 275 6.98E-22 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_01075 bb02e35821c17e3cecd714b7913bc79d 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 293 8.8E-26 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_01075 bb02e35821c17e3cecd714b7913bc79d 295 Gene3D G3DSA:1.10.3720.10 82 289 8.5E-18 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_06355 bf4589061860998bc1b15cc74763c2d6 268 SUPERFAMILY SSF55021 188 266 1.4E-19 T 31-10-2018 DFR86_06355 bf4589061860998bc1b15cc74763c2d6 268 Pfam PF00800 Prephenate dehydratase 10 184 9.0E-45 T 31-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 DFR86_06355 bf4589061860998bc1b15cc74763c2d6 268 Gene3D G3DSA:3.40.190.10 90 172 2.8E-39 T 31-10-2018 DFR86_06355 bf4589061860998bc1b15cc74763c2d6 268 Gene3D G3DSA:3.30.70.260 184 268 1.3E-19 T 31-10-2018 DFR86_06355 bf4589061860998bc1b15cc74763c2d6 268 SUPERFAMILY SSF53850 10 188 2.06E-40 T 31-10-2018 DFR86_06355 bf4589061860998bc1b15cc74763c2d6 268 Pfam PF01842 ACT domain 192 238 1.0E-7 T 31-10-2018 IPR002912 ACT domain DFR86_06355 bf4589061860998bc1b15cc74763c2d6 268 Gene3D G3DSA:3.40.190.10 12 181 2.8E-39 T 31-10-2018 DFR86_05960 2835bcea6b8ab65df89c790624aab507 118 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 5 111 19.938 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05960 2835bcea6b8ab65df89c790624aab507 118 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 21 92 1.0E-18 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05960 2835bcea6b8ab65df89c790624aab507 118 Pfam PF01282 Ribosomal protein S24e 33 108 4.1E-23 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05960 2835bcea6b8ab65df89c790624aab507 118 SUPERFAMILY SSF54189 14 113 1.87E-28 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05960 2835bcea6b8ab65df89c790624aab507 118 Gene3D G3DSA:3.30.70.330 6 110 2.0E-28 T 31-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily DFR86_01160 2d126de789be24dac0ebb9414ef80884 178 SUPERFAMILY SSF53335 28 172 9.29E-27 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_01160 2d126de789be24dac0ebb9414ef80884 178 Gene3D G3DSA:3.40.50.150 2 176 5.4E-41 T 31-10-2018 DFR86_01160 2d126de789be24dac0ebb9414ef80884 178 Pfam PF08241 Methyltransferase domain 36 126 5.8E-18 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR86_05190 ed02328c7735417eabfe1ca1a96100b4 141 Gene3D G3DSA:3.90.79.10 1 134 5.2E-39 T 31-10-2018 DFR86_05190 ed02328c7735417eabfe1ca1a96100b4 141 Pfam PF00293 NUDIX domain 6 118 1.2E-19 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 DFR86_05190 ed02328c7735417eabfe1ca1a96100b4 141 PRINTS PR00502 NUDIX hydrolase family signature 32 46 1.2E-5 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 DFR86_05190 ed02328c7735417eabfe1ca1a96100b4 141 PRINTS PR00502 NUDIX hydrolase family signature 46 61 1.2E-5 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 DFR86_05190 ed02328c7735417eabfe1ca1a96100b4 141 SUPERFAMILY SSF55811 2 129 3.25E-37 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 DFR86_05190 ed02328c7735417eabfe1ca1a96100b4 141 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DFR86_08910 2e5d8fa3e6fa24545ec9b88b7a1779ca 188 SUPERFAMILY SSF110324 6 58 4.45E-11 T 31-10-2018 DFR86_08910 2e5d8fa3e6fa24545ec9b88b7a1779ca 188 SUPERFAMILY SSF50249 67 178 7.8E-20 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_08910 2e5d8fa3e6fa24545ec9b88b7a1779ca 188 Gene3D G3DSA:2.20.70.10 146 180 3.4E-10 T 31-10-2018 DFR86_08910 2e5d8fa3e6fa24545ec9b88b7a1779ca 188 Gene3D G3DSA:2.40.50.100 6 54 1.5E-11 T 31-10-2018 DFR86_08910 2e5d8fa3e6fa24545ec9b88b7a1779ca 188 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 10 42 7.2E-9 T 31-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR86_08910 2e5d8fa3e6fa24545ec9b88b7a1779ca 188 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 7 184 24.116 T 31-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 DFR86_08910 2e5d8fa3e6fa24545ec9b88b7a1779ca 188 Gene3D G3DSA:2.40.50.140 61 145 6.0E-18 T 31-10-2018 DFR86_08910 2e5d8fa3e6fa24545ec9b88b7a1779ca 188 SMART SM00316 64 139 1.1E-4 T 31-10-2018 IPR022967 RNA-binding domain, S1 DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 518 1.7E-20 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 20 181 1.5E-13 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 Pfam PF00037 4Fe-4S binding domain 568 590 1.7E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 Gene3D G3DSA:3.40.50.970 375 525 1.8E-16 T 31-10-2018 DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 Gene3D G3DSA:3.40.50.970 2 183 4.8E-50 T 31-10-2018 DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 PIRSF PIRSF006439 1 595 1.6E-191 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 SUPERFAMILY SSF52518 9 215 1.29E-54 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 SUPERFAMILY SSF52518 347 547 1.33E-27 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 574 585 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 Gene3D G3DSA:3.30.70.20 537 604 2.2E-10 T 31-10-2018 DFR86_11375 cc2295148ef7dfdb6c33fb352cf58ce9 605 SUPERFAMILY SSF54862 525 600 2.55E-17 T 31-10-2018 DFR86_04450 eddd2440545a2c4945f98ecde311328a 318 SMART SM00382 31 229 3.8E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_04450 eddd2440545a2c4945f98ecde311328a 318 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_04450 eddd2440545a2c4945f98ecde311328a 318 Pfam PF00005 ABC transporter 22 178 7.2E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_04450 eddd2440545a2c4945f98ecde311328a 318 Gene3D G3DSA:3.40.50.300 1 317 3.9E-83 T 31-10-2018 DFR86_04450 eddd2440545a2c4945f98ecde311328a 318 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 309 9.8E-14 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_04450 eddd2440545a2c4945f98ecde311328a 318 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 291 2.2E-12 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_04450 eddd2440545a2c4945f98ecde311328a 318 SUPERFAMILY SSF52540 2 250 1.04E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06255 f142c59bf69322feaf1f5aedae8286c9 425 Pfam PF00390 Malic enzyme, N-terminal domain 111 148 1.5E-6 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DFR86_06255 f142c59bf69322feaf1f5aedae8286c9 425 Pfam PF00390 Malic enzyme, N-terminal domain 16 107 8.9E-18 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DFR86_06255 f142c59bf69322feaf1f5aedae8286c9 425 PIRSF PIRSF000106 26 420 8.9E-79 T 31-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 DFR86_06255 f142c59bf69322feaf1f5aedae8286c9 425 Pfam PF03949 Malic enzyme, NAD binding domain 161 390 1.2E-20 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 DFR86_06255 f142c59bf69322feaf1f5aedae8286c9 425 SUPERFAMILY SSF51735 160 415 3.49E-69 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_06255 f142c59bf69322feaf1f5aedae8286c9 425 SUPERFAMILY SSF53223 9 158 4.96E-53 T 31-10-2018 DFR86_06255 f142c59bf69322feaf1f5aedae8286c9 425 Gene3D G3DSA:3.40.50.10380 1 157 6.0E-70 T 31-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 DFR86_06255 f142c59bf69322feaf1f5aedae8286c9 425 SMART SM01274 15 148 2.0E-73 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DFR86_06255 f142c59bf69322feaf1f5aedae8286c9 425 Gene3D G3DSA:3.40.50.720 158 425 4.1E-86 T 31-10-2018 DFR86_06255 f142c59bf69322feaf1f5aedae8286c9 425 SMART SM00919 160 392 2.5E-107 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 DFR86_01625 9c8b578678f74e85b6d2a35ca324d4ed 362 Gene3D G3DSA:3.90.180.10 15 359 7.2E-116 T 31-10-2018 DFR86_01625 9c8b578678f74e85b6d2a35ca324d4ed 362 Gene3D G3DSA:3.40.50.720 149 334 7.2E-116 T 31-10-2018 DFR86_01625 9c8b578678f74e85b6d2a35ca324d4ed 362 Pfam PF16912 Glucose dehydrogenase C-terminus 147 360 1.4E-31 T 31-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 DFR86_01625 9c8b578678f74e85b6d2a35ca324d4ed 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 140 4.4E-23 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR86_01625 9c8b578678f74e85b6d2a35ca324d4ed 362 SUPERFAMILY SSF50129 1 163 3.2E-36 T 31-10-2018 IPR011032 GroES-like superfamily DFR86_01625 9c8b578678f74e85b6d2a35ca324d4ed 362 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 DFR86_01625 9c8b578678f74e85b6d2a35ca324d4ed 362 Hamap MF_02127 Glucose 1-dehydrogenase [gdh]. 1 362 59.012 T 31-10-2018 IPR026583 Glucose 1-dehydrogenase GO:0005536|GO:0008270|GO:0047936 KEGG: 00030+1.1.1.47 DFR86_01625 9c8b578678f74e85b6d2a35ca324d4ed 362 SUPERFAMILY SSF51735 184 319 1.42E-10 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_01070 bf301ad8736503ed5a4ab42862caf73a 343 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 14 34 0.0012 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal DFR86_01070 bf301ad8736503ed5a4ab42862caf73a 343 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 341 9.9E-38 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_01070 bf301ad8736503ed5a4ab42862caf73a 343 SUPERFAMILY SSF161098 97 329 1.44E-10 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_05975 64f7f7a83c739877cad6e26287550e71 222 SMART SM00220 1 219 0.0061 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR86_05975 64f7f7a83c739877cad6e26287550e71 222 SUPERFAMILY SSF56112 3 174 9.58E-24 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR86_05975 64f7f7a83c739877cad6e26287550e71 222 Gene3D G3DSA:3.30.200.20 12 84 3.0E-22 T 31-10-2018 DFR86_05975 64f7f7a83c739877cad6e26287550e71 222 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 6 211 2.4E-74 T 31-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 DFR86_05975 64f7f7a83c739877cad6e26287550e71 222 Gene3D G3DSA:1.10.510.10 95 212 6.8E-29 T 31-10-2018 DFR86_05975 64f7f7a83c739877cad6e26287550e71 222 Pfam PF00069 Protein kinase domain 70 156 8.2E-10 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR86_09395 6ff8d3c2b54d07e891827611e1587926 345 Gene3D G3DSA:4.10.1250.10 223 259 2.5E-9 T 31-10-2018 DFR86_09395 6ff8d3c2b54d07e891827611e1587926 345 SUPERFAMILY SSF103025 3 264 4.08E-62 T 31-10-2018 DFR86_09395 6ff8d3c2b54d07e891827611e1587926 345 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 343 1.0E-77 T 31-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 DFR86_09395 6ff8d3c2b54d07e891827611e1587926 345 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 241 6.8E-65 T 31-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain DFR86_09395 6ff8d3c2b54d07e891827611e1587926 345 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 249 341 3.6E-19 T 31-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DFR86_09395 6ff8d3c2b54d07e891827611e1587926 345 Gene3D G3DSA:3.30.70.1400 51 133 3.4E-56 T 31-10-2018 DFR86_09395 6ff8d3c2b54d07e891827611e1587926 345 SUPERFAMILY SSF101790 257 344 4.41E-19 T 31-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal DFR86_09395 6ff8d3c2b54d07e891827611e1587926 345 PIRSF PIRSF006487 1 345 1.7E-73 T 31-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 DFR86_09395 6ff8d3c2b54d07e891827611e1587926 345 Gene3D G3DSA:2.40.30.110 266 340 2.5E-19 T 31-10-2018 DFR86_09395 6ff8d3c2b54d07e891827611e1587926 345 Gene3D G3DSA:3.30.1360.120 5 220 3.4E-56 T 31-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 31-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 3.8E-44 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.8E-44 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 3.8E-44 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 3.8E-44 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 3.8E-44 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 3.8E-44 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 SUPERFAMILY SSF51735 6 243 5.39E-79 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 4.8E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 4.8E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 4.8E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 Gene3D G3DSA:3.40.50.720 2 250 6.4E-82 T 31-10-2018 DFR86_04440 4e4dc1f0182d36201e97cc83e17df2b5 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 243 7.4E-63 T 31-10-2018 DFR86_06620 2add571de4ac672db70dbfff18e49c1d 99 SUPERFAMILY SSF50104 4 96 1.62E-29 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR86_06620 2add571de4ac672db70dbfff18e49c1d 99 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 98 26.266 T 31-10-2018 IPR022856 Ribosomal protein L21e, archaeal DFR86_06620 2add571de4ac672db70dbfff18e49c1d 99 Pfam PF01157 Ribosomal protein L21e 4 95 4.8E-31 T 31-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06620 2add571de4ac672db70dbfff18e49c1d 99 Gene3D G3DSA:2.30.30.70 2 96 1.0E-31 T 31-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_07505 53069b4f4676b88641173843f02b2649 51 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 49 5.6E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_07505 53069b4f4676b88641173843f02b2649 51 SUPERFAMILY SSF89447 4 44 1.34E-10 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR86_07505 53069b4f4676b88641173843f02b2649 51 Gene3D G3DSA:2.10.260.10 1 47 1.3E-18 T 31-10-2018 DFR86_07505 53069b4f4676b88641173843f02b2649 51 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 43 5.4E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_07505 53069b4f4676b88641173843f02b2649 51 SMART SM00966 7 51 9.7E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_02810 617cea3ed39de1aafa7089ce2d3304b9 526 Pfam PF04055 Radical SAM superfamily 214 396 2.0E-14 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_02810 617cea3ed39de1aafa7089ce2d3304b9 526 SUPERFAMILY SSF102114 213 441 1.96E-14 T 31-10-2018 DFR86_02810 617cea3ed39de1aafa7089ce2d3304b9 526 SMART SM00729 209 437 3.4E-17 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_02810 617cea3ed39de1aafa7089ce2d3304b9 526 Gene3D G3DSA:3.80.30.20 209 423 1.8E-21 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe DFR86_10010 015037680a9b280bfa95aa88b7b90a70 421 Pfam PF16661 Metallo-beta-lactamase superfamily domain 28 177 5.1E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_10010 015037680a9b280bfa95aa88b7b90a70 421 SMART SM01027 231 341 5.5E-33 T 31-10-2018 IPR022712 Beta-Casp domain DFR86_10010 015037680a9b280bfa95aa88b7b90a70 421 Gene3D G3DSA:3.60.15.10 8 394 1.4E-95 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_10010 015037680a9b280bfa95aa88b7b90a70 421 SMART SM00849 15 197 4.0E-14 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_10010 015037680a9b280bfa95aa88b7b90a70 421 SUPERFAMILY SSF56281 5 421 7.85E-96 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_10010 015037680a9b280bfa95aa88b7b90a70 421 Pfam PF10996 Beta-Casp domain 238 341 4.6E-16 T 31-10-2018 IPR022712 Beta-Casp domain DFR86_10010 015037680a9b280bfa95aa88b7b90a70 421 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 355 413 4.9E-9 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain DFR86_10010 015037680a9b280bfa95aa88b7b90a70 421 Gene3D G3DSA:3.40.50.10890 199 363 1.4E-95 T 31-10-2018 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 Gene3D G3DSA:3.30.280.10 1 100 8.2E-41 T 31-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 PIRSF PIRSF001225 1 219 1.4E-94 T 31-10-2018 IPR008223 Urease, gamma-beta subunit GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 Gene3D G3DSA:2.10.150.10 107 219 4.7E-45 T 31-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 SUPERFAMILY SSF51278 113 218 1.83E-41 T 31-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 Pfam PF00547 Urease, gamma subunit 1 99 2.4E-39 T 31-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 Hamap MF_01955 Urease subunit alpha [ureA]. 1 219 42.837 T 31-10-2018 IPR008223 Urease, gamma-beta subunit GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 101 5.4E-41 T 31-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 Pfam PF00699 Urease beta subunit 109 200 2.3E-38 T 31-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 SUPERFAMILY SSF54111 1 103 3.01E-39 T 31-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 6.0E-36 T 31-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_04330 739fbd71f6fe3c61d94e85bf9271e936 219 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 109 203 9.2E-37 T 31-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR86_02925 34fbc30b7926cb3cbb928c8e3b9d0c3f 336 SUPERFAMILY SSF55205 1 226 1.18E-54 T 31-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 DFR86_02925 34fbc30b7926cb3cbb928c8e3b9d0c3f 336 Gene3D G3DSA:3.65.10.20 3 318 1.0E-100 T 31-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily DFR86_02925 34fbc30b7926cb3cbb928c8e3b9d0c3f 336 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 1 331 35.217 T 31-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 DFR86_02925 34fbc30b7926cb3cbb928c8e3b9d0c3f 336 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 2 323 5.1E-111 T 31-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 DFR86_02925 34fbc30b7926cb3cbb928c8e3b9d0c3f 336 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 153 163 - T 31-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site DFR86_02925 34fbc30b7926cb3cbb928c8e3b9d0c3f 336 Gene3D G3DSA:3.30.360.20 179 274 1.0E-100 T 31-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily DFR86_02925 34fbc30b7926cb3cbb928c8e3b9d0c3f 336 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 181 274 5.3E-22 T 31-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain DFR86_02925 34fbc30b7926cb3cbb928c8e3b9d0c3f 336 Pfam PF01137 RNA 3'-terminal phosphate cyclase 9 324 3.0E-65 T 31-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain DFR86_02925 34fbc30b7926cb3cbb928c8e3b9d0c3f 336 PIRSF PIRSF005378 1 329 8.6E-100 T 31-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 DFR86_11155 66bc212c350b7554e63b5e5d716dd029 168 Pfam PF01799 [2Fe-2S] binding domain 87 160 1.1E-31 T 31-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DFR86_11155 66bc212c350b7554e63b5e5d716dd029 168 Gene3D G3DSA:1.10.150.120 89 168 1.2E-33 T 31-10-2018 DFR86_11155 66bc212c350b7554e63b5e5d716dd029 168 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 20 69 8.8E-5 T 31-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DFR86_11155 66bc212c350b7554e63b5e5d716dd029 168 SUPERFAMILY SSF47741 98 165 7.46E-33 T 31-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily DFR86_11155 66bc212c350b7554e63b5e5d716dd029 168 SUPERFAMILY SSF54292 16 92 3.41E-25 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR86_11155 66bc212c350b7554e63b5e5d716dd029 168 Gene3D G3DSA:3.10.20.30 7 88 7.0E-31 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR86_09555 5ff7f6e16acbc8e1a178756d5e11fb8d 363 PIRSF PIRSF015578 1 362 9.9E-92 T 31-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 DFR86_09555 5ff7f6e16acbc8e1a178756d5e11fb8d 363 Gene3D G3DSA:3.30.360.10 191 303 4.4E-106 T 31-10-2018 DFR86_09555 5ff7f6e16acbc8e1a178756d5e11fb8d 363 Gene3D G3DSA:3.40.50.720 2 357 4.4E-106 T 31-10-2018 DFR86_09555 5ff7f6e16acbc8e1a178756d5e11fb8d 363 SUPERFAMILY SSF51735 2 356 3.94E-77 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_09555 5ff7f6e16acbc8e1a178756d5e11fb8d 363 Pfam PF01658 Myo-inositol-1-phosphate synthase 192 302 3.7E-30 T 31-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 DFR86_09555 5ff7f6e16acbc8e1a178756d5e11fb8d 363 SUPERFAMILY SSF55347 190 302 2.62E-30 T 31-10-2018 DFR86_11085 e9192b7dd7065237979c089e6ff97b7b 120 Gene3D G3DSA:3.40.1260.10 1 120 2.5E-23 T 31-10-2018 IPR027396 DsrEFH-like DFR86_11085 e9192b7dd7065237979c089e6ff97b7b 120 Pfam PF02635 DsrE/DsrF-like family 13 120 5.4E-10 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR86_11085 e9192b7dd7065237979c089e6ff97b7b 120 SUPERFAMILY SSF75169 3 120 7.91E-20 T 31-10-2018 IPR027396 DsrEFH-like DFR86_08975 e51280e3812227d45f8517c01b57c06a 95 Pfam PF00935 Ribosomal protein L44 16 91 1.7E-27 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_08975 e51280e3812227d45f8517c01b57c06a 95 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 92 3.0E-35 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_08975 e51280e3812227d45f8517c01b57c06a 95 Gene3D G3DSA:3.10.450.80 1 95 8.1E-30 T 31-10-2018 DFR86_08975 e51280e3812227d45f8517c01b57c06a 95 SUPERFAMILY SSF57829 1 92 1.56E-29 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR86_08975 e51280e3812227d45f8517c01b57c06a 95 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 91 23.878 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 Gene3D G3DSA:3.40.50.720 3 334 9.1E-110 T 31-10-2018 DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 SUPERFAMILY SSF55347 150 316 1.31E-36 T 31-10-2018 DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 142 2.1E-33 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 Gene3D G3DSA:3.30.360.10 148 316 9.1E-110 T 31-10-2018 DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 184 319 2.2E-7 T 31-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 342 40.03 T 31-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 Hamap MF_02083 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase [lysY]. 2 348 51.611 T 31-10-2018 IPR037535 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase GO:0016620 DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 SMART SM00859 3 142 2.7E-57 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 SUPERFAMILY SSF51735 1 163 1.08E-51 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 348 2.6E-127 T 31-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR86_07280 980c34fe68512a873ee83773a2e0a2cd 349 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 145 161 - T 31-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR86_09190 c3c4b1ee0c464bfb13335c008abfaf6e 351 Pfam PF01895 PhoU domain 142 230 2.1E-4 T 31-10-2018 IPR026022 PhoU domain DFR86_09190 c3c4b1ee0c464bfb13335c008abfaf6e 351 SUPERFAMILY SSF109755 127 288 1.44E-10 T 31-10-2018 DFR86_09190 c3c4b1ee0c464bfb13335c008abfaf6e 351 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 12 50 1.4E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_09190 c3c4b1ee0c464bfb13335c008abfaf6e 351 SMART SM00966 8 54 3.9E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_10435 f73fe67a41f3978b23e0b64a8fcf865e 557 SUPERFAMILY SSF56801 2 544 9.16E-122 T 31-10-2018 DFR86_10435 f73fe67a41f3978b23e0b64a8fcf865e 557 Gene3D G3DSA:3.40.50.12780 21 431 5.7E-73 T 31-10-2018 DFR86_10435 f73fe67a41f3978b23e0b64a8fcf865e 557 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 517 2.1E-18 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR86_10435 f73fe67a41f3978b23e0b64a8fcf865e 557 Pfam PF00501 AMP-binding enzyme 58 437 4.5E-73 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR86_10435 f73fe67a41f3978b23e0b64a8fcf865e 557 Gene3D G3DSA:3.30.300.30 433 554 4.2E-24 T 31-10-2018 DFR86_10435 f73fe67a41f3978b23e0b64a8fcf865e 557 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR86_10435 f73fe67a41f3978b23e0b64a8fcf865e 557 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 3 50 1.9E-10 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR86_04050 e2b407c0f004a0af34d6962fe3a71ffd 179 Gene3D G3DSA:1.10.3480.10 2 177 6.1E-30 T 31-10-2018 DFR86_04050 e2b407c0f004a0af34d6962fe3a71ffd 179 Pfam PF02613 Nitrate reductase delta subunit 35 146 6.5E-21 T 31-10-2018 IPR020945 DMSO/Nitrate reductase chaperone DFR86_04050 e2b407c0f004a0af34d6962fe3a71ffd 179 SUPERFAMILY SSF89155 33 174 2.49E-32 T 31-10-2018 IPR036411 TorD-like superfamily DFR86_09355 288b225e86b46cf6a8f3844ab3f2f291 41 SUPERFAMILY SSF47598 1 40 3.71E-7 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR86_09355 288b225e86b46cf6a8f3844ab3f2f291 41 Gene3D G3DSA:1.10.1220.10 1 41 6.3E-6 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DFR86_09355 288b225e86b46cf6a8f3844ab3f2f291 41 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 40 2.6E-9 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR86_05050 cbdf0b53d1a2b0e3ec50468022849b07 419 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 47 399 4.3E-89 T 31-10-2018 IPR017439 Amidohydrolase GO:0016787 DFR86_05050 cbdf0b53d1a2b0e3ec50468022849b07 419 Pfam PF07687 Peptidase dimerisation domain 214 307 5.1E-6 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR86_05050 cbdf0b53d1a2b0e3ec50468022849b07 419 SUPERFAMILY SSF53187 35 413 3.77E-62 T 31-10-2018 DFR86_05050 cbdf0b53d1a2b0e3ec50468022849b07 419 SUPERFAMILY SSF55031 211 321 3.27E-17 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain DFR86_05050 cbdf0b53d1a2b0e3ec50468022849b07 419 Gene3D G3DSA:3.30.70.360 209 322 3.2E-103 T 31-10-2018 DFR86_05050 cbdf0b53d1a2b0e3ec50468022849b07 419 Gene3D G3DSA:3.40.630.10 47 396 3.2E-103 T 31-10-2018 DFR86_05050 cbdf0b53d1a2b0e3ec50468022849b07 419 PIRSF PIRSF005962 30 416 1.3E-102 T 31-10-2018 IPR017439 Amidohydrolase GO:0016787 DFR86_05050 cbdf0b53d1a2b0e3ec50468022849b07 419 Pfam PF01546 Peptidase family M20/M25/M40 102 395 9.5E-17 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR86_09275 7502468436f25eb41c6f306b2cd74d28 211 Pfam PF04256 Protein of unknown function (DUF434) 6 61 2.1E-22 T 31-10-2018 IPR007368 Protein of unknown function DUF434 DFR86_09275 7502468436f25eb41c6f306b2cd74d28 211 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 10 58 2.0E-16 T 31-10-2018 IPR007368 Protein of unknown function DUF434 DFR86_01830 3bf5da0c90df46f2613cb2062aa3039a 543 SUPERFAMILY SSF161098 329 519 8.76E-16 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_01830 3bf5da0c90df46f2613cb2062aa3039a 543 SUPERFAMILY SSF161098 7 199 3.92E-16 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_01830 3bf5da0c90df46f2613cb2062aa3039a 543 Gene3D G3DSA:1.10.3720.10 2 209 3.9E-15 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_01830 3bf5da0c90df46f2613cb2062aa3039a 543 Gene3D G3DSA:1.10.3720.10 323 529 6.4E-15 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_01830 3bf5da0c90df46f2613cb2062aa3039a 543 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 341 532 5.5E-13 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_01830 3bf5da0c90df46f2613cb2062aa3039a 543 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 203 2.7E-8 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_00900 25cc48852d38ad0e7ae80c57ab185707 365 Pfam PF00535 Glycosyl transferase family 2 24 162 2.3E-12 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_00900 25cc48852d38ad0e7ae80c57ab185707 365 Gene3D G3DSA:3.90.550.10 7 213 3.8E-21 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00900 25cc48852d38ad0e7ae80c57ab185707 365 SUPERFAMILY SSF53448 9 300 6.19E-29 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_04480 d1e5bf8810496d5ad6738664e0dd4b30 853 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 341 497 7.0E-7 T 31-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR86_04480 d1e5bf8810496d5ad6738664e0dd4b30 853 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 548 726 1.2E-33 T 31-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR86_04480 d1e5bf8810496d5ad6738664e0dd4b30 853 Gene3D G3DSA:1.50.10.10 419 711 3.6E-9 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR86_04480 d1e5bf8810496d5ad6738664e0dd4b30 853 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 12 141 3.6E-18 T 31-10-2018 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR86_04480 d1e5bf8810496d5ad6738664e0dd4b30 853 SUPERFAMILY SSF48208 359 772 1.25E-19 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR86_05980 feff6c0ba24dff6160275c008ac90f50 185 SUPERFAMILY SSF52972 6 184 2.62E-58 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like DFR86_05980 feff6c0ba24dff6160275c008ac90f50 185 Gene3D G3DSA:3.90.950.10 6 185 1.7E-64 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like DFR86_05980 feff6c0ba24dff6160275c008ac90f50 185 Pfam PF01725 Ham1 family 7 182 1.6E-49 T 31-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 DFR86_05980 feff6c0ba24dff6160275c008ac90f50 185 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 7 184 3.2E-58 T 31-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 DFR86_05980 feff6c0ba24dff6160275c008ac90f50 185 Hamap MF_01405 dITP/XTP pyrophosphatase. 5 183 36.869 T 31-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 DFR86_02295 be4bb580031c4e0799202da004e91d14 267 Pfam PF13772 AIG2-like family 186 254 1.1E-8 T 31-10-2018 DFR86_02295 be4bb580031c4e0799202da004e91d14 267 Gene3D G3DSA:3.10.490.10 126 264 4.5E-22 T 31-10-2018 DFR86_02295 be4bb580031c4e0799202da004e91d14 267 SUPERFAMILY SSF110857 1 123 1.83E-27 T 31-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily DFR86_02295 be4bb580031c4e0799202da004e91d14 267 Gene3D G3DSA:3.10.490.10 1 125 8.2E-26 T 31-10-2018 DFR86_02295 be4bb580031c4e0799202da004e91d14 267 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 121 2.1E-19 T 31-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like DFR86_02295 be4bb580031c4e0799202da004e91d14 267 SUPERFAMILY SSF110857 129 256 1.28E-17 T 31-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily DFR86_10315 6b334344dc08ac201dea66803fe41590 480 Pfam PF07690 Major Facilitator Superfamily 12 400 5.4E-55 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_10315 6b334344dc08ac201dea66803fe41590 480 Gene3D G3DSA:1.20.1250.20 251 474 2.7E-20 T 31-10-2018 DFR86_10315 6b334344dc08ac201dea66803fe41590 480 Gene3D G3DSA:1.20.1720.10 8 241 4.7E-43 T 31-10-2018 DFR86_10315 6b334344dc08ac201dea66803fe41590 480 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 7 395 5.2E-73 T 31-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 DFR86_10315 6b334344dc08ac201dea66803fe41590 480 SUPERFAMILY SSF103473 6 465 5.23E-65 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_01990 1cc062490207a092fce6be70af179980 465 SUPERFAMILY SSF56235 14 227 1.63E-24 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_01990 1cc062490207a092fce6be70af179980 465 Gene3D G3DSA:3.60.20.10 2 244 5.0E-32 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_01990 1cc062490207a092fce6be70af179980 465 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 244 446 1.5E-46 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 DFR86_01990 1cc062490207a092fce6be70af179980 465 Pfam PF06508 Queuosine biosynthesis protein QueC 243 452 4.0E-59 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 DFR86_01990 1cc062490207a092fce6be70af179980 465 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 242 459 44.96 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 DFR86_01990 1cc062490207a092fce6be70af179980 465 Gene3D G3DSA:3.40.50.620 245 460 2.0E-57 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_01990 1cc062490207a092fce6be70af179980 465 SUPERFAMILY SSF52402 242 462 4.85E-49 T 31-10-2018 DFR86_01990 1cc062490207a092fce6be70af179980 465 Pfam PF13537 Glutamine amidotransferase domain 91 203 1.7E-16 T 31-10-2018 IPR017932 Glutamine amidotransferase type 2 domain DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Pfam PF00270 DEAD/DEAH box helicase 92 276 2.4E-10 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 SMART SM00487 85 295 1.4E-13 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 SUPERFAMILY SSF52540 43 273 1.17E-24 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 SMART SM00493 578 730 2.1E-27 T 31-10-2018 IPR006171 TOPRIM domain DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Gene3D G3DSA:1.10.460.10 761 1135 5.0E-130 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Gene3D G3DSA:3.40.50.300 70 290 5.1E-53 T 31-10-2018 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Pfam PF01751 Toprim domain 580 740 6.6E-23 T 31-10-2018 IPR006171 TOPRIM domain DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 SUPERFAMILY SSF52540 305 569 1.09E-31 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 SUPERFAMILY SSF56712 577 1142 1.44E-125 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 TIGRFAM TIGR01054 rgy: reverse gyrase 1 1140 0.0 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Hamap MF_01125 Reverse gyrase [rgy]. 1 1143 57.915 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Pfam PF01131 DNA topoisomerase 756 812 1.0E-13 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Pfam PF01131 DNA topoisomerase 836 1132 5.8E-58 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Gene3D G3DSA:3.40.50.300 291 480 2.4E-25 T 31-10-2018 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Gene3D G3DSA:3.40.50.300 492 577 4.2E-11 T 31-10-2018 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Gene3D G3DSA:1.10.290.10 856 979 5.0E-130 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Gene3D G3DSA:2.60.510.20 812 1040 5.0E-130 T 31-10-2018 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 SMART SM00437 846 1095 2.6E-79 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 Gene3D G3DSA:3.40.50.140 578 760 1.2E-26 T 31-10-2018 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 SMART SM00436 731 818 1.0E-35 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 704 717 2.5E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1056 1070 2.5E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 888 897 2.5E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 790 808 2.5E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09840 d1a28dc12ecef0dc0f35de993ee1608c 1152 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 968 984 2.5E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 3 546 1.3E-154 T 31-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 5.4E-19 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 5.4E-19 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 385 396 5.4E-19 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 5.4E-19 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 291 306 5.4E-19 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 561 38.281 T 31-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 SUPERFAMILY SSF47323 386 545 1.03E-36 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 Gene3D G3DSA:3.40.50.620 3 381 2.3E-143 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 SUPERFAMILY SSF57770 139 173 4.05E-12 T 31-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 Gene3D G3DSA:2.20.28.20 139 173 2.3E-143 T 31-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 Gene3D G3DSA:1.10.730.10 382 551 4.4E-43 T 31-10-2018 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 SUPERFAMILY SSF52374 2 384 1.66E-83 T 31-10-2018 DFR86_08675 7480e1f14d318b747f967f30f2a7fdd3 571 Pfam PF09334 tRNA synthetases class I (M) 3 398 6.9E-151 T 31-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_01275 5807bf520bc4fabc4aecd97a721084fd 552 SUPERFAMILY SSF52518 3 174 8.34E-45 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_01275 5807bf520bc4fabc4aecd97a721084fd 552 Gene3D G3DSA:3.40.50.970 341 552 1.2E-57 T 31-10-2018 DFR86_01275 5807bf520bc4fabc4aecd97a721084fd 552 Gene3D G3DSA:3.40.50.970 1 175 1.3E-53 T 31-10-2018 DFR86_01275 5807bf520bc4fabc4aecd97a721084fd 552 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 167 5.3E-42 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR86_01275 5807bf520bc4fabc4aecd97a721084fd 552 Gene3D G3DSA:3.40.50.1220 176 329 4.1E-36 T 31-10-2018 DFR86_01275 5807bf520bc4fabc4aecd97a721084fd 552 SUPERFAMILY SSF52467 183 357 1.0E-35 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_01275 5807bf520bc4fabc4aecd97a721084fd 552 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 312 1.4E-27 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DFR86_01275 5807bf520bc4fabc4aecd97a721084fd 552 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 373 516 3.7E-37 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR86_01275 5807bf520bc4fabc4aecd97a721084fd 552 SUPERFAMILY SSF52518 351 543 7.27E-55 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 SUPERFAMILY SSF52210 119 277 9.94E-41 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 Gene3D G3DSA:3.40.50.261 120 279 4.5E-60 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 279 37.562 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 148 175 - T 31-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 Pfam PF00549 CoA-ligase 147 264 1.3E-12 T 31-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 PRINTS PR01798 Succinyl-CoA synthase signature 235 252 8.2E-29 T 31-10-2018 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 PRINTS PR01798 Succinyl-CoA synthase signature 78 95 8.2E-29 T 31-10-2018 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 PRINTS PR01798 Succinyl-CoA synthase signature 171 189 8.2E-29 T 31-10-2018 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 PRINTS PR01798 Succinyl-CoA synthase signature 202 215 8.2E-29 T 31-10-2018 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 Gene3D G3DSA:3.40.50.720 1 119 9.6E-53 T 31-10-2018 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 SUPERFAMILY SSF51735 1 118 1.25E-42 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 1 278 7.3E-118 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 Pfam PF02629 CoA binding domain 2 95 8.1E-32 T 31-10-2018 IPR003781 CoA-binding GO:0048037 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 SMART SM00881 1 96 3.3E-35 T 31-10-2018 IPR003781 CoA-binding GO:0048037 DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 231 244 - T 31-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site DFR86_10135 6d25e865424d62d8f4061afe050c28cf 279 PIRSF PIRSF001553 1 279 8.7E-125 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR86_10685 f19ea4b959ab1fd63dfddc684794302a 423 Pfam PF01523 Putative modulator of DNA gyrase 19 288 1.3E-28 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 DFR86_10685 f19ea4b959ab1fd63dfddc684794302a 423 SUPERFAMILY SSF111283 3 421 2.62E-56 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 SUPERFAMILY SSF53748 7 406 3.3E-107 T 31-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 11 407 33.512 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 Pfam PF00162 Phosphoglycerate kinase 13 396 6.9E-102 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 Gene3D G3DSA:3.40.50.1260 199 397 2.8E-117 T 31-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 PRINTS PR00477 Phosphoglycerate kinase family signature 150 172 6.9E-55 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 PRINTS PR00477 Phosphoglycerate kinase family signature 180 202 6.9E-55 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 PRINTS PR00477 Phosphoglycerate kinase family signature 115 130 6.9E-55 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 PRINTS PR00477 Phosphoglycerate kinase family signature 383 400 6.9E-55 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 PRINTS PR00477 Phosphoglycerate kinase family signature 39 61 6.9E-55 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 PRINTS PR00477 Phosphoglycerate kinase family signature 16 32 6.9E-55 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 PRINTS PR00477 Phosphoglycerate kinase family signature 325 350 6.9E-55 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 PRINTS PR00477 Phosphoglycerate kinase family signature 203 222 6.9E-55 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 Gene3D G3DSA:3.40.50.1260 17 404 2.8E-117 T 31-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09325 cac89abb0112cb8cbdaa614a4e67d172 415 PIRSF PIRSF000724 5 414 4.2E-125 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_04775 18831c5c1fd4961ffcd396ef4e3cdc13 214 Pfam PF00753 Metallo-beta-lactamase superfamily 9 187 1.4E-20 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_04775 18831c5c1fd4961ffcd396ef4e3cdc13 214 Gene3D G3DSA:3.60.15.10 1 211 4.9E-57 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_04775 18831c5c1fd4961ffcd396ef4e3cdc13 214 SMART SM00849 12 187 4.3E-39 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_04775 18831c5c1fd4961ffcd396ef4e3cdc13 214 SUPERFAMILY SSF56281 3 204 5.9E-49 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_02630 d7b9e251380e2491567ce5a1ec093392 250 Gene3D G3DSA:2.60.200.30 97 226 1.1E-36 T 31-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 DFR86_02630 d7b9e251380e2491567ce5a1ec093392 250 Pfam PF01513 ATP-NAD kinase 34 228 1.7E-18 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 DFR86_02630 d7b9e251380e2491567ce5a1ec093392 250 Gene3D G3DSA:3.40.50.10330 34 235 1.1E-36 T 31-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 DFR86_02630 d7b9e251380e2491567ce5a1ec093392 250 SUPERFAMILY SSF111331 9 237 2.62E-38 T 31-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 141 410 8.9E-27 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 416 48.697 T 31-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 74 88 - T 31-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 SUPERFAMILY SSF52283 1 416 7.94E-96 T 31-10-2018 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 Gene3D G3DSA:3.40.50.720 185 344 6.0E-174 T 31-10-2018 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 Gene3D G3DSA:3.40.50.1480 5 405 6.0E-174 T 31-10-2018 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 PIRSF PIRSF001109 1 416 1.2E-187 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 SUPERFAMILY SSF51735 183 345 4.72E-67 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 SMART SM00997 183 344 5.5E-107 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 185 343 6.0E-56 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 205 221 - T 31-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 SMART SM00996 2 415 6.3E-155 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 2 136 2.1E-42 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR86_07210 0560a68c59a36c03f00e5efbae4f3c9b 416 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 3 416 1.2E-193 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 Gene3D G3DSA:2.40.30.10 464 553 1.2E-32 T 31-10-2018 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 Gene3D G3DSA:3.40.50.10050 353 455 6.5E-24 T 31-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 153 1.4E-17 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 PRINTS PR00315 GTP-binding elongation factor signature 10 23 6.6E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 PRINTS PR00315 GTP-binding elongation factor signature 128 137 6.6E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 PRINTS PR00315 GTP-binding elongation factor signature 76 86 6.6E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 PRINTS PR00315 GTP-binding elongation factor signature 92 103 6.6E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 Gene3D G3DSA:2.40.30.10 234 351 2.1E-38 T 31-10-2018 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 SUPERFAMILY SSF50447 463 589 8.25E-30 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 Pfam PF00009 Elongation factor Tu GTP binding domain 10 219 4.3E-31 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 Gene3D G3DSA:3.40.50.300 2 231 5.5E-61 T 31-10-2018 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 SUPERFAMILY SSF52540 6 293 5.72E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 5 586 1.2E-243 T 31-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 4 593 42.265 T 31-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 SUPERFAMILY SSF52156 337 457 4.71E-25 T 31-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 Pfam PF14578 Elongation factor Tu domain 4 465 550 7.3E-37 T 31-10-2018 IPR029459 Elongation factor Tu-type domain DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 Pfam PF11987 Translation-initiation factor 2 348 444 3.0E-13 T 31-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 DFR86_06260 6f1426780e6b5fab471be10857fc8048 597 Pfam PF03144 Elongation factor Tu domain 2 249 328 1.4E-9 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 DFR86_00480 13741fa7cf05bf88a4fa1c7708a248ec 244 Pfam PF00378 Enoyl-CoA hydratase/isomerase 6 243 1.5E-47 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR86_00480 13741fa7cf05bf88a4fa1c7708a248ec 244 Gene3D G3DSA:3.90.226.10 1 244 5.8E-61 T 31-10-2018 DFR86_00480 13741fa7cf05bf88a4fa1c7708a248ec 244 SUPERFAMILY SSF52096 3 244 5.89E-62 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR86_09010 db3f76e169b32e165b9748ed901c5094 289 Gene3D G3DSA:3.60.15.10 2 287 6.4E-68 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_09010 db3f76e169b32e165b9748ed901c5094 289 Pfam PF00753 Metallo-beta-lactamase superfamily 21 75 6.7E-8 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_09010 db3f76e169b32e165b9748ed901c5094 289 Pfam PF12706 Beta-lactamase superfamily domain 185 256 1.5E-10 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_09010 db3f76e169b32e165b9748ed901c5094 289 Hamap MF_01818 Ribonuclease BN [rbn]. 2 288 31.066 T 31-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 DFR86_09010 db3f76e169b32e165b9748ed901c5094 289 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 286 2.3E-90 T 31-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 DFR86_09010 db3f76e169b32e165b9748ed901c5094 289 SUPERFAMILY SSF56281 3 283 1.4E-56 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_08090 6ee234ea7d1efcb2641e98ecfe49d663 338 SMART SM00829 9 336 2.5E-4 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR86_08090 6ee234ea7d1efcb2641e98ecfe49d663 338 Gene3D G3DSA:3.40.50.720 148 284 2.7E-88 T 31-10-2018 DFR86_08090 6ee234ea7d1efcb2641e98ecfe49d663 338 Gene3D G3DSA:3.90.180.10 15 328 2.7E-88 T 31-10-2018 DFR86_08090 6ee234ea7d1efcb2641e98ecfe49d663 338 SUPERFAMILY SSF51735 134 305 2.63E-35 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_08090 6ee234ea7d1efcb2641e98ecfe49d663 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 121 1.3E-25 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR86_08090 6ee234ea7d1efcb2641e98ecfe49d663 338 Pfam PF00107 Zinc-binding dehydrogenase 170 299 2.3E-21 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR86_08090 6ee234ea7d1efcb2641e98ecfe49d663 338 SUPERFAMILY SSF50129 4 336 1.62E-39 T 31-10-2018 IPR011032 GroES-like superfamily DFR86_04860 e93f11ead689a47fcfdc5f82d10f19ac 445 SUPERFAMILY SSF55103 207 435 2.13E-43 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DFR86_04860 e93f11ead689a47fcfdc5f82d10f19ac 445 Pfam PF02913 FAD linked oxidases, C-terminal domain 205 433 2.0E-43 T 31-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 DFR86_04860 e93f11ead689a47fcfdc5f82d10f19ac 445 Gene3D G3DSA:3.30.465.40 3 219 1.7E-67 T 31-10-2018 DFR86_04860 e93f11ead689a47fcfdc5f82d10f19ac 445 SUPERFAMILY SSF56176 13 202 2.29E-59 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_04860 e93f11ead689a47fcfdc5f82d10f19ac 445 Pfam PF01565 FAD binding domain 25 164 3.4E-41 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_04860 e93f11ead689a47fcfdc5f82d10f19ac 445 Gene3D G3DSA:3.30.70.2740 314 390 5.9E-13 T 31-10-2018 DFR86_04860 e93f11ead689a47fcfdc5f82d10f19ac 445 Gene3D G3DSA:1.10.45.10 391 435 4.3E-8 T 31-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 SUPERFAMILY SSF57783 11 52 4.25E-11 T 31-10-2018 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 SUPERFAMILY SSF47954 119 210 2.8E-25 T 31-10-2018 IPR036915 Cyclin-like superfamily DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 PRINTS PR00685 Transcription initiation factor IIB signature 283 297 6.5E-55 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 PRINTS PR00685 Transcription initiation factor IIB signature 21 41 6.5E-55 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 PRINTS PR00685 Transcription initiation factor IIB signature 43 56 6.5E-55 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 PRINTS PR00685 Transcription initiation factor IIB signature 251 267 6.5E-55 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 PRINTS PR00685 Transcription initiation factor IIB signature 56 77 6.5E-55 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 PRINTS PR00685 Transcription initiation factor IIB signature 164 183 6.5E-55 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 PRINTS PR00685 Transcription initiation factor IIB signature 217 235 6.5E-55 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 PRINTS PR00685 Transcription initiation factor IIB signature 190 205 6.5E-55 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 Pfam PF08271 TFIIB zinc-binding 11 49 1.4E-11 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 SMART SM00385 216 297 1.2E-11 T 31-10-2018 IPR013763 Cyclin-like DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 SMART SM00385 122 203 3.5E-11 T 31-10-2018 IPR013763 Cyclin-like DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 Gene3D G3DSA:1.10.472.10 214 305 4.5E-25 T 31-10-2018 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 156 171 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 SUPERFAMILY SSF47954 213 304 5.31E-29 T 31-10-2018 IPR036915 Cyclin-like superfamily DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 3 303 43.792 T 31-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 Gene3D G3DSA:1.10.472.170 10 205 2.7E-61 T 31-10-2018 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 Pfam PF00382 Transcription factor TFIIB repeat 219 288 4.5E-16 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 Pfam PF00382 Transcription factor TFIIB repeat 126 193 1.2E-15 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 DFR86_05895 efc41a711f2c109ebc33a74c02deb392 306 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 250 265 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 330 36.087 T 31-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 Pfam PF00814 Glycoprotease family 26 297 2.1E-75 T 31-10-2018 IPR000905 Gcp-like domain DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 296 4.1E-79 T 31-10-2018 IPR017861 Kae1/TsaD family DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 3 329 2.5E-144 T 31-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 SUPERFAMILY SSF53067 1 299 7.56E-27 T 31-10-2018 DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 3.0E-34 T 31-10-2018 IPR017861 Kae1/TsaD family DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 74 94 3.0E-34 T 31-10-2018 IPR017861 Kae1/TsaD family DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 127 139 3.0E-34 T 31-10-2018 IPR017861 Kae1/TsaD family DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 253 262 3.0E-34 T 31-10-2018 IPR017861 Kae1/TsaD family DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 95 114 3.0E-34 T 31-10-2018 IPR017861 Kae1/TsaD family DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 149 170 3.0E-34 T 31-10-2018 IPR017861 Kae1/TsaD family DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 Gene3D G3DSA:3.30.420.40 125 283 1.2E-85 T 31-10-2018 DFR86_05970 ec781ce6233ba6b6cc563f0da88abcfb 331 Gene3D G3DSA:3.30.420.40 3 305 1.2E-85 T 31-10-2018 DFR86_02345 b907b1ac5b77e14da09f18a9e9e2c05a 559 SUPERFAMILY SSF143975 3 379 4.97E-135 T 31-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR86_02345 b907b1ac5b77e14da09f18a9e9e2c05a 559 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 31-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR86_02345 b907b1ac5b77e14da09f18a9e9e2c05a 559 Gene3D G3DSA:3.50.30.80 380 528 5.5E-55 T 31-10-2018 DFR86_02345 b907b1ac5b77e14da09f18a9e9e2c05a 559 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 466 477 - T 31-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR86_02345 b907b1ac5b77e14da09f18a9e9e2c05a 559 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 6 558 46.439 T 31-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR86_02345 b907b1ac5b77e14da09f18a9e9e2c05a 559 SUPERFAMILY SSF52016 380 557 4.39E-61 T 31-10-2018 DFR86_02345 b907b1ac5b77e14da09f18a9e9e2c05a 559 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 19 557 3.6E-220 T 31-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR86_02345 b907b1ac5b77e14da09f18a9e9e2c05a 559 Pfam PF00920 Dehydratase family 36 555 1.8E-210 T 31-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR86_11300 52426ff2608cfb0ec60708c5d9c0da9e 269 Gene3D G3DSA:1.20.140.10 156 267 1.1E-13 T 31-10-2018 DFR86_11300 52426ff2608cfb0ec60708c5d9c0da9e 269 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 154 212 9.7E-7 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DFR86_11300 52426ff2608cfb0ec60708c5d9c0da9e 269 SUPERFAMILY SSF47203 157 264 3.54E-18 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR86_04545 a4fc1c88f991d860cfb844cea378c5e5 427 SMART SM01274 12 145 2.3E-75 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DFR86_04545 a4fc1c88f991d860cfb844cea378c5e5 427 SUPERFAMILY SSF51735 157 420 4.24E-68 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_04545 a4fc1c88f991d860cfb844cea378c5e5 427 SUPERFAMILY SSF53223 8 155 1.15E-51 T 31-10-2018 DFR86_04545 a4fc1c88f991d860cfb844cea378c5e5 427 Gene3D G3DSA:3.40.50.720 155 426 2.0E-84 T 31-10-2018 DFR86_04545 a4fc1c88f991d860cfb844cea378c5e5 427 SMART SM00919 157 389 9.7E-105 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 DFR86_04545 a4fc1c88f991d860cfb844cea378c5e5 427 Gene3D G3DSA:3.40.50.10380 2 154 5.6E-66 T 31-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 DFR86_04545 a4fc1c88f991d860cfb844cea378c5e5 427 Pfam PF00390 Malic enzyme, N-terminal domain 111 145 4.8E-6 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DFR86_04545 a4fc1c88f991d860cfb844cea378c5e5 427 Pfam PF00390 Malic enzyme, N-terminal domain 13 110 3.7E-19 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DFR86_04545 a4fc1c88f991d860cfb844cea378c5e5 427 PIRSF PIRSF000106 23 421 7.4E-77 T 31-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 DFR86_04545 a4fc1c88f991d860cfb844cea378c5e5 427 Pfam PF03949 Malic enzyme, NAD binding domain 158 388 6.4E-21 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 DFR86_08110 882b7de87a051052140ade619b90d1de 375 Gene3D G3DSA:3.40.50.620 4 198 1.7E-58 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_08110 882b7de87a051052140ade619b90d1de 375 Pfam PF01171 PP-loop family 23 177 3.3E-8 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 DFR86_08110 882b7de87a051052140ade619b90d1de 375 SUPERFAMILY SSF54810 193 375 4.71E-29 T 31-10-2018 DFR86_08110 882b7de87a051052140ade619b90d1de 375 SUPERFAMILY SSF52402 7 219 5.07E-40 T 31-10-2018 DFR86_08110 882b7de87a051052140ade619b90d1de 375 Gene3D G3DSA:3.30.300.10 282 375 1.6E-24 T 31-10-2018 DFR86_08110 882b7de87a051052140ade619b90d1de 375 Pfam PF00958 GMP synthase C terminal domain 298 374 5.9E-20 T 31-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 3.7E-9 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 3.7E-9 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00097 Anthranilate synthase component II signature 126 138 4.0E-33 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00097 Anthranilate synthase component II signature 50 59 4.0E-33 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00097 Anthranilate synthase component II signature 5 19 4.0E-33 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00097 Anthranilate synthase component II signature 105 113 4.0E-33 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00097 Anthranilate synthase component II signature 80 91 4.0E-33 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00097 Anthranilate synthase component II signature 170 183 4.0E-33 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 Gene3D G3DSA:3.40.50.880 3 194 1.7E-66 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 170 183 4.0E-14 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 4.0E-14 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 4.0E-14 T 31-10-2018 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 6 193 4.2E-60 T 31-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 Pfam PF00117 Glutamine amidotransferase class-I 7 191 2.5E-49 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR86_09520 0c14cf4844edf8b6a8cf5dfa8d722314 194 SUPERFAMILY SSF52317 5 192 6.18E-53 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_00335 1c2eef8af74fb3254adab629bb545699 492 SUPERFAMILY SSF54862 353 440 1.74E-13 T 31-10-2018 DFR86_00335 1c2eef8af74fb3254adab629bb545699 492 Pfam PF00037 4Fe-4S binding domain 359 375 7.5E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_00335 1c2eef8af74fb3254adab629bb545699 492 Gene3D G3DSA:3.30.70.20 356 417 1.2E-8 T 31-10-2018 DFR86_06485 dc6ab4b7e724685eeb435cdc740de479 81 Gene3D G3DSA:3.10.20.30 1 81 5.3E-17 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR86_06485 dc6ab4b7e724685eeb435cdc740de479 81 SUPERFAMILY SSF54285 3 81 2.83E-9 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp DFR86_06485 dc6ab4b7e724685eeb435cdc740de479 81 Pfam PF09138 Urm1 (Ubiquitin related modifier) 18 81 5.2E-5 T 31-10-2018 IPR015221 Ubiquitin-related modifier 1 GO:0005737|GO:0034227 Reactome: R-HSA-6782315 DFR86_00740 115907e23c3530ecaf948d56cdff4407 164 Gene3D G3DSA:3.40.630.30 3 162 1.8E-35 T 31-10-2018 DFR86_00740 115907e23c3530ecaf948d56cdff4407 164 SUPERFAMILY SSF55729 2 141 1.3E-24 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR86_00740 115907e23c3530ecaf948d56cdff4407 164 Pfam PF00583 Acetyltransferase (GNAT) family 37 133 3.8E-11 T 31-10-2018 IPR000182 GNAT domain DFR86_03170 80d5a172476a32c337e1735b2194a3d1 444 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 253 2.7E-70 T 31-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DFR86_03170 80d5a172476a32c337e1735b2194a3d1 444 SUPERFAMILY SSF53639 264 440 2.24E-46 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR86_03170 80d5a172476a32c337e1735b2194a3d1 444 Gene3D G3DSA:3.40.225.10 260 443 1.4E-48 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR86_03170 80d5a172476a32c337e1735b2194a3d1 444 SUPERFAMILY SSF53613 7 256 8.02E-58 T 31-10-2018 IPR029056 Ribokinase-like DFR86_03170 80d5a172476a32c337e1735b2194a3d1 444 Pfam PF08543 Phosphomethylpyrimidine kinase 13 253 8.3E-72 T 31-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 DFR86_03170 80d5a172476a32c337e1735b2194a3d1 444 Pfam PF10120 Thiamine-phosphate synthase 270 437 2.3E-45 T 31-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DFR86_03170 80d5a172476a32c337e1735b2194a3d1 444 Gene3D G3DSA:3.40.1190.20 3 257 6.9E-68 T 31-10-2018 IPR029056 Ribokinase-like DFR86_09850 b83e91742aa625f87ce09ff94d50767e 921 Pfam PF00271 Helicase conserved C-terminal domain 240 335 4.1E-13 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_09850 b83e91742aa625f87ce09ff94d50767e 921 SMART SM00490 257 335 1.2E-14 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_09850 b83e91742aa625f87ce09ff94d50767e 921 Gene3D G3DSA:3.40.50.300 214 426 4.4E-24 T 31-10-2018 DFR86_09850 b83e91742aa625f87ce09ff94d50767e 921 Pfam PF00270 DEAD/DEAH box helicase 21 191 3.4E-28 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_09850 b83e91742aa625f87ce09ff94d50767e 921 PIRSF PIRSF037307 1 921 2.4E-215 T 31-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 DFR86_09850 b83e91742aa625f87ce09ff94d50767e 921 SMART SM00487 16 218 1.4E-34 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_09850 b83e91742aa625f87ce09ff94d50767e 921 Gene3D G3DSA:3.40.50.300 2 206 1.7E-43 T 31-10-2018 DFR86_09850 b83e91742aa625f87ce09ff94d50767e 921 SUPERFAMILY SSF52540 30 353 2.52E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07825 a4d1f3d0aa391f1bba2f8da79de718eb 384 Gene3D G3DSA:3.50.50.60 118 262 6.8E-88 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_07825 a4d1f3d0aa391f1bba2f8da79de718eb 384 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 314 3.6E-9 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_07825 a4d1f3d0aa391f1bba2f8da79de718eb 384 SUPERFAMILY SSF51905 1 154 4.95E-19 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_07825 a4d1f3d0aa391f1bba2f8da79de718eb 384 SUPERFAMILY SSF51905 121 253 5.18E-31 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_07825 a4d1f3d0aa391f1bba2f8da79de718eb 384 Gene3D G3DSA:3.50.50.60 4 318 6.8E-88 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_09865 554e9698dc9cd13639de75f9cb28d26f 311 Pfam PF01916 Deoxyhypusine synthase 27 307 1.7E-101 T 31-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 DFR86_09865 554e9698dc9cd13639de75f9cb28d26f 311 SUPERFAMILY SSF52467 3 310 2.78E-99 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_09865 554e9698dc9cd13639de75f9cb28d26f 311 Gene3D G3DSA:3.40.910.10 1 311 1.0E-92 T 31-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 DFR86_09865 554e9698dc9cd13639de75f9cb28d26f 311 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 22 310 41.826 T 31-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 DFR86_08340 8183ec34a1c46d08fdd8f17dc8e628f7 221 SMART SM01211 1 220 5.9E-92 T 31-10-2018 DFR86_08340 8183ec34a1c46d08fdd8f17dc8e628f7 221 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 220 4.7E-90 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR86_08340 8183ec34a1c46d08fdd8f17dc8e628f7 221 PIRSF PIRSF001586 1 221 1.7E-75 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR86_08340 8183ec34a1c46d08fdd8f17dc8e628f7 221 SUPERFAMILY SSF52317 2 203 1.53E-60 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_08340 8183ec34a1c46d08fdd8f17dc8e628f7 221 Gene3D G3DSA:3.40.50.880 1 220 6.3E-65 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_08340 8183ec34a1c46d08fdd8f17dc8e628f7 221 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 202 8.7E-44 T 31-10-2018 DFR86_08340 8183ec34a1c46d08fdd8f17dc8e628f7 221 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 221 37.839 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR86_10260 cccd96056b0dedd40ceb4cf7a8dd5c85 208 Pfam PF16955 Ferrous iron uptake permease, iron-lead transporter 1 207 2.8E-95 T 31-10-2018 IPR031594 Putative iron/lead transporter DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 Gene3D G3DSA:3.90.740.10 177 343 4.3E-216 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 Gene3D G3DSA:3.40.50.620 24 536 4.3E-216 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 SUPERFAMILY SSF50677 194 341 1.7E-47 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 SUPERFAMILY SSF52374 2 580 2.02E-115 T 31-10-2018 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 Gene3D G3DSA:1.10.730.10 5 743 4.3E-216 T 31-10-2018 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 Pfam PF08264 Anticodon-binding domain of tRNA 614 755 3.4E-30 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 PRINTS PR00986 Valyl-tRNA synthetase signature 487 505 1.3E-12 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 1.3E-12 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 1.3E-12 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 PRINTS PR00986 Valyl-tRNA synthetase signature 456 477 1.3E-12 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 TIGRFAM TIGR00422 valS: valine--tRNA ligase 5 794 8.1E-215 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 SUPERFAMILY SSF47323 587 794 4.11E-48 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_09505 2c16fc021c166d33bc56b8c849cf42d0 801 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 571 1.9E-126 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_05320 5aa7273d8b5b58f60d82fa384efd0df7 447 SMART SM00382 40 164 3.0E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_05320 5aa7273d8b5b58f60d82fa384efd0df7 447 Gene3D G3DSA:3.40.50.300 4 161 7.3E-39 T 31-10-2018 DFR86_05320 5aa7273d8b5b58f60d82fa384efd0df7 447 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 44 145 4.6E-15 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_05320 5aa7273d8b5b58f60d82fa384efd0df7 447 SUPERFAMILY SSF52540 3 224 5.65E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_05320 5aa7273d8b5b58f60d82fa384efd0df7 447 Gene3D G3DSA:1.10.8.60 166 226 3.5E-15 T 31-10-2018 DFR86_05320 5aa7273d8b5b58f60d82fa384efd0df7 447 Hamap MF_01508 Replication factor C large subunit [rfcL]. 3 447 33.171 T 31-10-2018 IPR023935 Replication factor C, large subunit DFR86_05470 ebd87a1f13648d87b56726322554f26f 209 SUPERFAMILY SSF46785 3 58 1.07E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_05470 ebd87a1f13648d87b56726322554f26f 209 Gene3D G3DSA:1.10.10.10 1 136 2.3E-41 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_05470 ebd87a1f13648d87b56726322554f26f 209 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 56 5.3E-10 T 31-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 DFR86_05470 ebd87a1f13648d87b56726322554f26f 209 SMART SM00899 139 209 1.3E-5 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 DFR86_05470 ebd87a1f13648d87b56726322554f26f 209 SMART SM00529 25 123 4.6E-39 T 31-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 DFR86_05470 ebd87a1f13648d87b56726322554f26f 209 SUPERFAMILY SSF50037 129 208 1.95E-5 T 31-10-2018 IPR008988 Transcriptional repressor, C-terminal DFR86_05470 ebd87a1f13648d87b56726322554f26f 209 SUPERFAMILY SSF47979 63 133 6.67E-24 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 DFR86_05470 ebd87a1f13648d87b56726322554f26f 209 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 131 1.4E-27 T 31-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 DFR86_05470 ebd87a1f13648d87b56726322554f26f 209 Pfam PF04023 FeoA domain 141 208 8.0E-6 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 DFR86_06175 763a5d5ecb74555a9da0492c1e1bc1a4 183 Gene3D G3DSA:3.40.50.150 3 182 4.2E-37 T 31-10-2018 DFR86_06175 763a5d5ecb74555a9da0492c1e1bc1a4 183 Pfam PF05175 Methyltransferase small domain 16 179 2.4E-36 T 31-10-2018 IPR007848 Methyltransferase small domain GO:0008168 DFR86_06175 763a5d5ecb74555a9da0492c1e1bc1a4 183 SUPERFAMILY SSF53335 15 176 3.15E-30 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 PIRSF PIRSF500175 18 437 2.2E-177 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 Gene3D G3DSA:2.30.30.520 9 80 1.2E-14 T 31-10-2018 IPR037222 GatD, N-terminal DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 PIRSF PIRSF001220 87 428 4.2E-118 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 Gene3D G3DSA:3.40.50.40 301 439 9.2E-50 T 31-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 SUPERFAMILY SSF53774 82 436 4.19E-106 T 31-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 Gene3D G3DSA:3.40.50.1170 81 300 5.0E-70 T 31-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 PRINTS PR00139 Asparaginase/glutaminase family signature 93 104 1.8E-15 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 PRINTS PR00139 Asparaginase/glutaminase family signature 169 187 1.8E-15 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 PRINTS PR00139 Asparaginase/glutaminase family signature 354 372 1.8E-15 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 24 433 46.013 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 91 429 4.2E-127 T 31-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 36 432 7.9E-177 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 170 180 - T 31-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 SMART SM00870 92 417 4.5E-133 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 Pfam PF00710 Asparaginase, N-terminal 93 284 2.5E-58 T 31-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 DFR86_09700 ea4eabb1cea49cc8e278f964d80b65da 443 SUPERFAMILY SSF141300 5 74 3.01E-16 T 31-10-2018 IPR037222 GatD, N-terminal DFR86_03915 f2866669c48bba01ac2dc140bc3caac8 217 ProSitePatterns PS00079 Multicopper oxidases signature 1. 184 204 - T 31-10-2018 IPR033138 Multicopper oxidases, conserved site DFR86_03915 f2866669c48bba01ac2dc140bc3caac8 217 Gene3D G3DSA:2.60.40.420 38 206 3.3E-22 T 31-10-2018 IPR008972 Cupredoxin DFR86_03915 f2866669c48bba01ac2dc140bc3caac8 217 TIGRFAM TIGR03094 sulfo_cyanin: sulfocyanin 55 216 3.1E-57 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR86_03915 f2866669c48bba01ac2dc140bc3caac8 217 SUPERFAMILY SSF49503 70 205 1.5E-19 T 31-10-2018 IPR008972 Cupredoxin DFR86_03915 f2866669c48bba01ac2dc140bc3caac8 217 Pfam PF06525 Sulfocyanin (SoxE) domain 71 216 1.6E-61 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR86_03915 f2866669c48bba01ac2dc140bc3caac8 217 PIRSF PIRSF022145 4 217 7.3E-75 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR86_09265 183941c947a607a8bd75f8f7d458d38a 104 Gene3D G3DSA:1.10.10.1410 1 58 2.9E-27 T 31-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09265 183941c947a607a8bd75f8f7d458d38a 104 Pfam PF00428 60s Acidic ribosomal protein 17 103 1.3E-20 T 31-10-2018 DFR86_09265 183941c947a607a8bd75f8f7d458d38a 104 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 104 1.5E-43 T 31-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 DFR86_09265 183941c947a607a8bd75f8f7d458d38a 104 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 101 13.053 T 31-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_01740 c21c4538d1e7c9365174d33104e413a6 117 Gene3D G3DSA:3.30.420.130 1 117 1.2E-38 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily DFR86_01740 c21c4538d1e7c9365174d33104e413a6 117 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 16 99 5.0E-11 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis DFR86_01740 c21c4538d1e7c9365174d33104e413a6 117 SUPERFAMILY SSF53146 1 115 9.03E-23 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily DFR86_07970 448ed28e591fed2fa2a7bb1bbe563815 319 SUPERFAMILY SSF89733 2 312 5.1E-72 T 31-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 DFR86_07970 448ed28e591fed2fa2a7bb1bbe563815 319 Gene3D G3DSA:3.30.1370.60 60 288 2.8E-71 T 31-10-2018 DFR86_07970 448ed28e591fed2fa2a7bb1bbe563815 319 Gene3D G3DSA:3.30.60.50 170 217 2.8E-71 T 31-10-2018 DFR86_07970 448ed28e591fed2fa2a7bb1bbe563815 319 Gene3D G3DSA:1.10.1530.10 25 59 2.8E-71 T 31-10-2018 DFR86_07970 448ed28e591fed2fa2a7bb1bbe563815 319 Pfam PF02615 Malate/L-lactate dehydrogenase 4 284 1.2E-75 T 31-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 DFR86_02090 4cd3e689c6ca6b295cd3d3ca98bf2957 359 Gene3D G3DSA:3.50.50.100 1 358 9.1E-65 T 31-10-2018 DFR86_02090 4cd3e689c6ca6b295cd3d3ca98bf2957 359 SUPERFAMILY SSF51905 1 296 6.33E-20 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_02090 4cd3e689c6ca6b295cd3d3ca98bf2957 359 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 270 5.9E-23 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_05825 d12f46ad3371b66bc4829bdd95072774 411 Gene3D G3DSA:3.40.1360.10 161 258 4.5E-12 T 31-10-2018 DFR86_05825 d12f46ad3371b66bc4829bdd95072774 411 Hamap MF_00007 DNA primase DnaG [dnaG]. 1 405 32.329 T 31-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 DFR86_05825 d12f46ad3371b66bc4829bdd95072774 411 SUPERFAMILY SSF110455 166 263 8.11E-10 T 31-10-2018 DFR86_05825 d12f46ad3371b66bc4829bdd95072774 411 Pfam PF13662 Toprim domain 167 230 1.5E-9 T 31-10-2018 IPR006171 TOPRIM domain DFR86_05825 d12f46ad3371b66bc4829bdd95072774 411 SMART SM00493 165 237 1.6E-7 T 31-10-2018 IPR006171 TOPRIM domain DFR86_04725 af5d279082b512cf4a46cde69be0cf6a 185 Pfam PF07185 Protein of unknown function (DUF1404) 2 181 6.0E-39 T 31-10-2018 IPR009844 Protein of unknown function DUF1404 DFR86_11280 d58405a522036496fc6cc5325fc164a9 105 SUPERFAMILY SSF50022 5 90 1.7E-15 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_11280 d58405a522036496fc6cc5325fc164a9 105 Pfam PF00355 Rieske [2Fe-2S] domain 5 70 8.2E-10 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR86_11280 d58405a522036496fc6cc5325fc164a9 105 Gene3D G3DSA:2.102.10.10 1 94 6.3E-13 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_07360 2cd662efec22b88822d27e5311cc26ed 228 Pfam PF00121 Triosephosphate isomerase 5 122 4.2E-12 T 31-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_07360 2cd662efec22b88822d27e5311cc26ed 228 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 3 221 38.28 T 31-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 DFR86_07360 2cd662efec22b88822d27e5311cc26ed 228 Gene3D G3DSA:3.20.20.70 1 224 4.4E-75 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_07360 2cd662efec22b88822d27e5311cc26ed 228 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 208 6.5E-46 T 31-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_07360 2cd662efec22b88822d27e5311cc26ed 228 SUPERFAMILY SSF51351 1 216 1.31E-40 T 31-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 SUPERFAMILY SSF56003 110 679 9.16E-120 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 Gene3D G3DSA:3.30.365.10 341 416 2.6E-29 T 31-10-2018 DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 Gene3D G3DSA:3.90.1170.50 25 118 1.4E-69 T 31-10-2018 DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 SUPERFAMILY SSF54665 2 136 6.15E-32 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 12 118 3.0E-22 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 Gene3D G3DSA:3.30.365.10 547 680 3.2E-35 T 31-10-2018 DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 159 629 3.2E-90 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 Gene3D G3DSA:3.30.365.10 11 259 1.4E-69 T 31-10-2018 DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 SMART SM01008 11 118 5.3E-30 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 Gene3D G3DSA:3.30.365.10 417 508 2.6E-29 T 31-10-2018 DFR86_10860 c5f203fa7bc0ac815869263dc2e7c0a4 685 Gene3D G3DSA:3.30.365.10 119 333 1.4E-69 T 31-10-2018 DFR86_06820 0134df9a96dff41266a4bd338d3b4405 138 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 10 138 2.9E-63 T 31-10-2018 IPR019971 Ribosomal protein L14P, archaeal DFR86_06820 0134df9a96dff41266a4bd338d3b4405 138 Gene3D G3DSA:2.40.150.20 3 138 1.5E-51 T 31-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_06820 0134df9a96dff41266a4bd338d3b4405 138 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 17 138 21.262 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DFR86_06820 0134df9a96dff41266a4bd338d3b4405 138 SMART SM01374 17 138 5.2E-67 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DFR86_06820 0134df9a96dff41266a4bd338d3b4405 138 SUPERFAMILY SSF50193 11 138 3.14E-47 T 31-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_06820 0134df9a96dff41266a4bd338d3b4405 138 Pfam PF00238 Ribosomal protein L14p/L23e 18 138 2.4E-38 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DFR86_06820 0134df9a96dff41266a4bd338d3b4405 138 ProSitePatterns PS00049 Ribosomal protein L14 signature. 77 103 - T 31-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 Gene3D G3DSA:3.40.50.620 4 267 1.8E-87 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 Gene3D G3DSA:3.40.50.620 284 475 1.5E-53 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 SMART SM00893 287 469 5.1E-29 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 SMART SM00893 25 218 1.9E-56 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 SUPERFAMILY SSF52467 478 595 1.69E-45 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 SUPERFAMILY SSF52402 5 262 5.37E-71 T 31-10-2018 DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 Gene3D G3DSA:3.40.50.1220 476 600 6.4E-53 T 31-10-2018 DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 SUPERFAMILY SSF52402 287 470 1.26E-41 T 31-10-2018 DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 478 560 6.1E-34 T 31-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 Pfam PF01012 Electron transfer flavoprotein domain 26 212 2.0E-46 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR86_11315 00cd3afcd24f512334da99d4eee93fd7 601 Pfam PF01012 Electron transfer flavoprotein domain 287 459 1.4E-33 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR86_08350 5035e03244e93e1baf3bea1829a6fd8f 236 Gene3D G3DSA:3.30.200.20 5 231 2.1E-80 T 31-10-2018 DFR86_08350 5035e03244e93e1baf3bea1829a6fd8f 236 Pfam PF01259 SAICAR synthetase 5 227 1.1E-51 T 31-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR86_08350 5035e03244e93e1baf3bea1829a6fd8f 236 ProSitePatterns PS01057 SAICAR synthetase signature 1. 83 97 - T 31-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR86_08350 5035e03244e93e1baf3bea1829a6fd8f 236 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 5 212 1.1E-58 T 31-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 DFR86_08350 5035e03244e93e1baf3bea1829a6fd8f 236 Gene3D G3DSA:3.30.470.20 82 220 2.1E-80 T 31-10-2018 DFR86_08350 5035e03244e93e1baf3bea1829a6fd8f 236 SUPERFAMILY SSF56104 4 232 1.11E-69 T 31-10-2018 DFR86_08350 5035e03244e93e1baf3bea1829a6fd8f 236 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 2 234 27.425 T 31-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR86_11630 e7183506ad2d937a1271268bba3683e1 147 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 8 143 3.3E-10 T 31-10-2018 IPR010160 CRISPR-associated protein, Cmr5 DFR86_11630 e7183506ad2d937a1271268bba3683e1 147 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 10 90 8.0E-7 T 31-10-2018 IPR010160 CRISPR-associated protein, Cmr5 DFR86_11630 e7183506ad2d937a1271268bba3683e1 147 SUPERFAMILY SSF158568 9 144 5.62E-13 T 31-10-2018 IPR023101 AF1862-like domain superfamily DFR86_11630 e7183506ad2d937a1271268bba3683e1 147 Gene3D G3DSA:1.10.520.30 3 93 6.6E-6 T 31-10-2018 IPR023101 AF1862-like domain superfamily DFR86_11000 2cb7df9a156b9ddd8ac72932109d35f4 726 SUPERFAMILY SSF56003 111 723 2.36E-170 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR86_11000 2cb7df9a156b9ddd8ac72932109d35f4 726 Gene3D G3DSA:3.30.365.10 429 586 6.3E-111 T 31-10-2018 DFR86_11000 2cb7df9a156b9ddd8ac72932109d35f4 726 SMART SM01008 17 118 1.3E-38 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_11000 2cb7df9a156b9ddd8ac72932109d35f4 726 Gene3D G3DSA:3.30.365.10 172 263 3.9E-57 T 31-10-2018 DFR86_11000 2cb7df9a156b9ddd8ac72932109d35f4 726 Gene3D G3DSA:3.90.1170.50 1 118 5.5E-36 T 31-10-2018 DFR86_11000 2cb7df9a156b9ddd8ac72932109d35f4 726 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 17 118 7.7E-27 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_11000 2cb7df9a156b9ddd8ac72932109d35f4 726 Gene3D G3DSA:3.30.365.10 346 710 6.3E-111 T 31-10-2018 DFR86_11000 2cb7df9a156b9ddd8ac72932109d35f4 726 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 136 666 1.1E-153 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR86_11000 2cb7df9a156b9ddd8ac72932109d35f4 726 Gene3D G3DSA:3.30.365.10 137 337 3.9E-57 T 31-10-2018 DFR86_11000 2cb7df9a156b9ddd8ac72932109d35f4 726 SUPERFAMILY SSF54665 2 134 3.66E-38 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR86_03900 7a50f1bd7bf768c9249529c9218bc33a 1132 Gene3D G3DSA:3.30.200.50 16 91 8.2E-14 T 31-10-2018 DFR86_03900 7a50f1bd7bf768c9249529c9218bc33a 1132 Gene3D G3DSA:3.30.200.50 97 159 3.8E-5 T 31-10-2018 DFR86_03900 7a50f1bd7bf768c9249529c9218bc33a 1132 SUPERFAMILY SSF50692 981 1108 3.16E-27 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR86_03900 7a50f1bd7bf768c9249529c9218bc33a 1132 Gene3D G3DSA:3.40.228.10 364 535 1.3E-25 T 31-10-2018 DFR86_03900 7a50f1bd7bf768c9249529c9218bc33a 1132 Gene3D G3DSA:3.40.50.740 543 831 1.9E-14 T 31-10-2018 DFR86_03900 7a50f1bd7bf768c9249529c9218bc33a 1132 Gene3D G3DSA:3.40.50.740 168 361 1.2E-15 T 31-10-2018 DFR86_03900 7a50f1bd7bf768c9249529c9218bc33a 1132 Pfam PF01568 Molydopterin dinucleotide binding domain 1003 1094 8.0E-15 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 DFR86_03900 7a50f1bd7bf768c9249529c9218bc33a 1132 Gene3D G3DSA:2.40.40.20 979 1112 2.1E-38 T 31-10-2018 DFR86_03900 7a50f1bd7bf768c9249529c9218bc33a 1132 SUPERFAMILY SSF53706 21 886 1.26E-61 T 31-10-2018 DFR86_03035 f8ce7f3b8292a6f45ea363810847ab1b 363 Gene3D G3DSA:3.40.720.10 31 356 5.3E-33 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR86_03035 f8ce7f3b8292a6f45ea363810847ab1b 363 SUPERFAMILY SSF53649 34 359 3.93E-45 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 DFR86_03035 f8ce7f3b8292a6f45ea363810847ab1b 363 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 41 272 1.9E-14 T 31-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 DFR86_11725 70cccd52449495249262132f34abc39f 1221 SUPERFAMILY SSF52540 421 1066 2.13E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_11725 70cccd52449495249262132f34abc39f 1221 Gene3D G3DSA:3.40.50.300 916 1068 5.8E-12 T 31-10-2018 DFR86_11725 70cccd52449495249262132f34abc39f 1221 Pfam PF00271 Helicase conserved C-terminal domain 978 1038 1.7E-8 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_11725 70cccd52449495249262132f34abc39f 1221 SMART SM00490 951 1039 5.8E-8 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_11725 70cccd52449495249262132f34abc39f 1221 SUPERFAMILY SSF52540 327 481 1.02E-5 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_11170 8e481a62d428012f78e2a0e166ec042e 323 Gene3D G3DSA:3.30.465.40 3 190 2.9E-29 T 31-10-2018 DFR86_11170 8e481a62d428012f78e2a0e166ec042e 323 Pfam PF01565 FAD binding domain 8 135 2.5E-20 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_11170 8e481a62d428012f78e2a0e166ec042e 323 SUPERFAMILY SSF56176 8 174 7.48E-31 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_08965 0737f4e9383bfa4721a079bfddf75bf3 263 Pfam PF00575 S1 RNA binding domain 9 83 3.8E-12 T 31-10-2018 IPR003029 S1 domain GO:0003676 DFR86_08965 0737f4e9383bfa4721a079bfddf75bf3 263 Gene3D G3DSA:2.40.50.140 1 84 3.3E-27 T 31-10-2018 DFR86_08965 0737f4e9383bfa4721a079bfddf75bf3 263 SMART SM00316 10 83 4.3E-16 T 31-10-2018 IPR022967 RNA-binding domain, S1 DFR86_08965 0737f4e9383bfa4721a079bfddf75bf3 263 SUPERFAMILY SSF50249 7 88 4.65E-19 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_08965 0737f4e9383bfa4721a079bfddf75bf3 263 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 230 1.5E-21 T 31-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 DFR86_08965 0737f4e9383bfa4721a079bfddf75bf3 263 Gene3D G3DSA:1.10.150.190 85 174 3.2E-26 T 31-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 DFR86_08965 0737f4e9383bfa4721a079bfddf75bf3 263 Gene3D G3DSA:3.30.70.1130 175 263 3.2E-21 T 31-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 DFR86_08965 0737f4e9383bfa4721a079bfddf75bf3 263 SUPERFAMILY SSF116742 85 170 5.1E-23 T 31-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 DFR86_08965 0737f4e9383bfa4721a079bfddf75bf3 263 SUPERFAMILY SSF110993 177 260 7.59E-19 T 31-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 DFR86_04660 75681056563888d30578a4f12b7721ca 491 SUPERFAMILY SSF56645 1 273 1.39E-76 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR86_04660 75681056563888d30578a4f12b7721ca 491 Gene3D G3DSA:1.10.3140.10 1 146 2.9E-34 T 31-10-2018 DFR86_04660 75681056563888d30578a4f12b7721ca 491 Gene3D G3DSA:1.20.140.10 278 487 2.4E-47 T 31-10-2018 DFR86_04660 75681056563888d30578a4f12b7721ca 491 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 272 6.4E-86 T 31-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal DFR86_04660 75681056563888d30578a4f12b7721ca 491 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 284 477 9.6E-47 T 31-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal DFR86_04660 75681056563888d30578a4f12b7721ca 491 PIRSF PIRSF000331 1 491 1.7E-163 T 31-10-2018 IPR004925 HpaB/PvcC/4-BUDH DFR86_04660 75681056563888d30578a4f12b7721ca 491 SUPERFAMILY SSF47203 264 479 1.55E-35 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR86_04660 75681056563888d30578a4f12b7721ca 491 Gene3D G3DSA:2.40.110.10 147 274 9.9E-37 T 31-10-2018 DFR86_07040 43ef89f3bee8e720bcc55516daa2c1db 288 Gene3D G3DSA:1.10.10.10 4 93 1.7E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_07040 43ef89f3bee8e720bcc55516daa2c1db 288 Pfam PF09202 Rio2, N-terminal 14 89 1.4E-7 T 31-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 DFR86_07040 43ef89f3bee8e720bcc55516daa2c1db 288 SMART SM00090 67 286 2.6E-32 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 DFR86_07040 43ef89f3bee8e720bcc55516daa2c1db 288 Gene3D G3DSA:3.30.200.20 95 191 1.4E-24 T 31-10-2018 DFR86_07040 43ef89f3bee8e720bcc55516daa2c1db 288 SUPERFAMILY SSF46785 6 89 1.01E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_07040 43ef89f3bee8e720bcc55516daa2c1db 288 Gene3D G3DSA:1.10.510.10 193 285 2.1E-21 T 31-10-2018 DFR86_07040 43ef89f3bee8e720bcc55516daa2c1db 288 Pfam PF01163 RIO1 family 109 276 1.3E-36 T 31-10-2018 DFR86_07040 43ef89f3bee8e720bcc55516daa2c1db 288 SUPERFAMILY SSF56112 101 256 3.01E-25 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR86_10880 9a63cd6fb728af47e0547583f25f782f 147 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 138 35.085 T 31-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 DFR86_10880 9a63cd6fb728af47e0547583f25f782f 147 Pfam PF01597 Glycine cleavage H-protein 15 135 1.3E-42 T 31-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate DFR86_10880 9a63cd6fb728af47e0547583f25f782f 147 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 56 85 - T 31-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 DFR86_10880 9a63cd6fb728af47e0547583f25f782f 147 Gene3D G3DSA:2.40.50.100 1 129 2.2E-38 T 31-10-2018 DFR86_10880 9a63cd6fb728af47e0547583f25f782f 147 SUPERFAMILY SSF51230 19 135 1.44E-35 T 31-10-2018 IPR011053 Single hybrid motif DFR86_10825 434ada29887c5dd1e6937755089edc2a 358 Gene3D G3DSA:3.30.390.50 260 348 4.4E-17 T 31-10-2018 DFR86_10825 434ada29887c5dd1e6937755089edc2a 358 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 273 345 1.1E-6 T 31-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 DFR86_10825 434ada29887c5dd1e6937755089edc2a 358 SUPERFAMILY SSF55681 7 239 7.21E-36 T 31-10-2018 DFR86_10825 434ada29887c5dd1e6937755089edc2a 358 SUPERFAMILY SSF82649 275 346 6.28E-6 T 31-10-2018 DFR86_10825 434ada29887c5dd1e6937755089edc2a 358 Gene3D G3DSA:3.30.930.10 8 250 4.2E-35 T 31-10-2018 DFR86_10995 582385346213efd00876cc0f4c22b474 359 Gene3D G3DSA:1.25.40.10 160 286 1.7E-17 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 Gene3D G3DSA:1.25.40.10 290 359 3.6E-6 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 SUPERFAMILY SSF48452 8 219 1.25E-43 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 SMART SM00028 110 143 0.084 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 SMART SM00028 76 109 8.4E-4 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 SMART SM00028 188 221 9.7 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 SMART SM00028 8 41 0.35 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 SMART SM00028 308 341 4.2E-4 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 SMART SM00028 42 75 7.9E-4 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 Pfam PF14559 Tetratricopeptide repeat 53 113 2.3E-8 T 31-10-2018 DFR86_10995 582385346213efd00876cc0f4c22b474 359 Gene3D G3DSA:1.25.40.10 6 66 2.3E-12 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 Pfam PF07719 Tetratricopeptide repeat 308 340 1.2E-5 T 31-10-2018 IPR013105 Tetratricopeptide repeat 2 DFR86_10995 582385346213efd00876cc0f4c22b474 359 Gene3D G3DSA:1.25.40.10 67 159 6.9E-22 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 Pfam PF13181 Tetratricopeptide repeat 192 219 0.085 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 Pfam PF13181 Tetratricopeptide repeat 13 40 0.18 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_10995 582385346213efd00876cc0f4c22b474 359 SUPERFAMILY SSF48452 159 344 4.17E-23 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_09210 ee005a364e91f288c673a0169c604a91 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 18.47 T 31-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_09210 ee005a364e91f288c673a0169c604a91 51 Gene3D G3DSA:1.10.1620.10 2 50 1.1E-18 T 31-10-2018 IPR023626 Ribosomal protein L39e domain superfamily DFR86_09210 ee005a364e91f288c673a0169c604a91 51 SUPERFAMILY SSF48662 4 51 9.15E-19 T 31-10-2018 IPR023626 Ribosomal protein L39e domain superfamily DFR86_09210 ee005a364e91f288c673a0169c604a91 51 Pfam PF00832 Ribosomal L39 protein 9 50 9.0E-21 T 31-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_09210 ee005a364e91f288c673a0169c604a91 51 ProSitePatterns PS00051 Ribosomal protein L39e signature. 30 46 - T 31-10-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_07305 2e1a8bbe157d81687c24f6b0c1fd8a4b 387 Gene3D G3DSA:3.40.640.10 46 286 7.8E-128 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_07305 2e1a8bbe157d81687c24f6b0c1fd8a4b 387 SUPERFAMILY SSF53383 7 376 2.29E-115 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_07305 2e1a8bbe157d81687c24f6b0c1fd8a4b 387 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 375 4.0E-130 T 31-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 DFR86_07305 2e1a8bbe157d81687c24f6b0c1fd8a4b 387 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 204 241 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_07305 2e1a8bbe157d81687c24f6b0c1fd8a4b 387 Pfam PF00202 Aminotransferase class-III 12 374 7.2E-112 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_07305 2e1a8bbe157d81687c24f6b0c1fd8a4b 387 Gene3D G3DSA:3.90.1150.10 14 371 7.8E-128 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_07305 2e1a8bbe157d81687c24f6b0c1fd8a4b 387 PIRSF PIRSF000521 107 142 0.0011 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_07305 2e1a8bbe157d81687c24f6b0c1fd8a4b 387 PIRSF PIRSF000521 155 379 2.1E-39 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_07305 2e1a8bbe157d81687c24f6b0c1fd8a4b 387 PIRSF PIRSF000521 11 115 2.9E-7 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_07305 2e1a8bbe157d81687c24f6b0c1fd8a4b 387 Hamap MF_02084 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase [lysJ]. 4 378 48.661 T 31-10-2018 IPR037537 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase GO:0008483 DFR86_06315 cf35cc0b07bf4270d702d284ef47837a 314 Gene3D G3DSA:3.30.1330.10 1 134 5.8E-21 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_06315 cf35cc0b07bf4270d702d284ef47837a 314 Pfam PF00586 AIR synthase related protein, N-terminal domain 39 131 2.0E-9 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR86_06315 cf35cc0b07bf4270d702d284ef47837a 314 SUPERFAMILY SSF56042 139 297 9.24E-16 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_06315 cf35cc0b07bf4270d702d284ef47837a 314 SUPERFAMILY SSF55326 31 131 4.36E-17 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_06315 cf35cc0b07bf4270d702d284ef47837a 314 Gene3D G3DSA:3.90.650.10 139 310 1.8E-17 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_08785 a40860d95c8f140c4980777c839eec73 358 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 256 284 0.002 T 31-10-2018 IPR001451 Hexapeptide repeat DFR86_08785 a40860d95c8f140c4980777c839eec73 358 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 290 323 0.0011 T 31-10-2018 IPR001451 Hexapeptide repeat DFR86_08785 a40860d95c8f140c4980777c839eec73 358 SUPERFAMILY SSF53448 1 307 1.1E-69 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_08785 a40860d95c8f140c4980777c839eec73 358 SUPERFAMILY SSF51161 289 346 4.24E-6 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily DFR86_08785 a40860d95c8f140c4980777c839eec73 358 Gene3D G3DSA:3.90.550.10 1 225 1.7E-65 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_08785 a40860d95c8f140c4980777c839eec73 358 Pfam PF00483 Nucleotidyl transferase 4 224 1.2E-40 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR86_08785 a40860d95c8f140c4980777c839eec73 358 Gene3D G3DSA:2.160.10.10 226 355 9.1E-20 T 31-10-2018 DFR86_04145 ec310b20c4ead54ecdc229b22eb9c58f 438 SUPERFAMILY SSF52540 38 231 1.27E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04145 ec310b20c4ead54ecdc229b22eb9c58f 438 Pfam PF13173 AAA domain 46 179 2.6E-24 T 31-10-2018 DFR86_04145 ec310b20c4ead54ecdc229b22eb9c58f 438 Pfam PF13635 Domain of unknown function (DUF4143) 261 391 2.8E-9 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 DFR86_09110 8915d18109776c586f3d71326a7ecbab 323 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 132 146 3.0E-22 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_09110 8915d18109776c586f3d71326a7ecbab 323 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 305 322 3.0E-22 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_09110 8915d18109776c586f3d71326a7ecbab 323 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 273 289 3.0E-22 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_09110 8915d18109776c586f3d71326a7ecbab 323 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 161 171 3.0E-22 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_09110 8915d18109776c586f3d71326a7ecbab 323 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 238 3.0E-22 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_09110 8915d18109776c586f3d71326a7ecbab 323 Pfam PF01189 16S rRNA methyltransferase RsmB/F 151 294 3.3E-31 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 DFR86_09110 8915d18109776c586f3d71326a7ecbab 323 Gene3D G3DSA:2.30.130.70 41 135 5.0E-5 T 31-10-2018 DFR86_09110 8915d18109776c586f3d71326a7ecbab 323 Gene3D G3DSA:3.40.50.150 141 323 2.8E-45 T 31-10-2018 DFR86_09110 8915d18109776c586f3d71326a7ecbab 323 SUPERFAMILY SSF88697 58 111 1.62E-5 T 31-10-2018 IPR015947 PUA-like superfamily DFR86_09110 8915d18109776c586f3d71326a7ecbab 323 SUPERFAMILY SSF53335 10 323 1.58E-43 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_05415 a68095ceb5faab0a02d629e239c7956b 739 Gene3D G3DSA:3.40.50.12320 220 386 1.5E-26 T 31-10-2018 DFR86_05415 a68095ceb5faab0a02d629e239c7956b 739 SUPERFAMILY SSF52540 147 346 3.49E-10 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_05415 a68095ceb5faab0a02d629e239c7956b 739 Gene3D G3DSA:3.40.630.30 388 585 9.1E-45 T 31-10-2018 DFR86_05415 a68095ceb5faab0a02d629e239c7956b 739 Pfam PF05127 Helicase 225 396 1.9E-43 T 31-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 DFR86_05415 a68095ceb5faab0a02d629e239c7956b 739 SUPERFAMILY SSF55729 496 567 1.95E-10 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR86_05415 a68095ceb5faab0a02d629e239c7956b 739 Pfam PF13718 GNAT acetyltransferase 2 426 536 1.2E-18 T 31-10-2018 IPR000182 GNAT domain DFR86_05415 a68095ceb5faab0a02d629e239c7956b 739 Pfam PF08351 Domain of unknown function (DUF1726) 81 166 2.5E-20 T 31-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 DFR86_06710 c3745825211d143c0dc6dc24d2ef3633 72 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 72 22.409 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06710 c3745825211d143c0dc6dc24d2ef3633 72 Gene3D G3DSA:2.20.25.30 9 72 1.2E-24 T 31-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06710 c3745825211d143c0dc6dc24d2ef3633 72 SUPERFAMILY SSF57829 9 71 4.58E-22 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR86_06710 c3745825211d143c0dc6dc24d2ef3633 72 Pfam PF01780 Ribosomal L37ae protein family 4 71 4.1E-27 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05280 b1af7d69f25285b1b672d5514a1b86c3 211 PIRSF PIRSF037213 1 211 7.4E-71 T 31-10-2018 IPR017139 Uncharacterised conserved protein UCP037213 DFR86_05280 b1af7d69f25285b1b672d5514a1b86c3 211 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 113 203 1.1E-30 T 31-10-2018 IPR019254 Protein of unknown function DUF2250 DFR86_05280 b1af7d69f25285b1b672d5514a1b86c3 211 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 10 100 4.2E-38 T 31-10-2018 IPR019254 Protein of unknown function DUF2250 DFR86_08555 fafb10c49584b166095e0260f7e56757 123 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 10 120 1.8E-37 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR86_08555 fafb10c49584b166095e0260f7e56757 123 SUPERFAMILY SSF56276 11 119 2.94E-33 T 31-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 DFR86_08555 fafb10c49584b166095e0260f7e56757 123 Gene3D G3DSA:3.60.90.10 3 122 7.7E-34 T 31-10-2018 DFR86_08555 fafb10c49584b166095e0260f7e56757 123 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 9 122 27.069 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR86_08555 fafb10c49584b166095e0260f7e56757 123 Pfam PF02675 S-adenosylmethionine decarboxylase 16 119 6.1E-33 T 31-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR86_07940 317e3032dd5b0dd877ad804f17fec707 744 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 2 700 6.9E-231 T 31-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 DFR86_07940 317e3032dd5b0dd877ad804f17fec707 744 Gene3D G3DSA:1.10.10.470 476 576 8.4E-178 T 31-10-2018 DFR86_07940 317e3032dd5b0dd877ad804f17fec707 744 SMART SM00642 8 634 5.8E-7 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR86_07940 317e3032dd5b0dd877ad804f17fec707 744 Gene3D G3DSA:3.30.1590.10 85 202 8.4E-178 T 31-10-2018 DFR86_07940 317e3032dd5b0dd877ad804f17fec707 744 Gene3D G3DSA:1.10.150.200 304 432 8.4E-178 T 31-10-2018 DFR86_07940 317e3032dd5b0dd877ad804f17fec707 744 SUPERFAMILY SSF51445 4 672 1.9E-116 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR86_07940 317e3032dd5b0dd877ad804f17fec707 744 Pfam PF00128 Alpha amylase, catalytic domain 16 234 2.8E-25 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR86_07940 317e3032dd5b0dd877ad804f17fec707 744 Gene3D G3DSA:3.20.20.80 2 670 8.4E-178 T 31-10-2018 DFR86_00975 f292beb598fb54e7e4f7565461c6574c 488 Pfam PF13476 AAA domain 214 361 3.0E-12 T 31-10-2018 IPR038729 Rad50/SbcC-type AAA domain DFR86_00975 f292beb598fb54e7e4f7565461c6574c 488 SMART SM00382 231 457 1.3E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_00975 f292beb598fb54e7e4f7565461c6574c 488 Gene3D G3DSA:3.40.50.300 212 312 2.9E-11 T 31-10-2018 DFR86_00975 f292beb598fb54e7e4f7565461c6574c 488 Gene3D G3DSA:3.40.50.300 327 451 4.4E-6 T 31-10-2018 DFR86_00975 f292beb598fb54e7e4f7565461c6574c 488 SUPERFAMILY SSF52540 213 436 2.84E-19 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 Gene3D G3DSA:3.40.50.1370 5 134 1.6E-102 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 295 1.8E-24 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 1.8E-24 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 1.8E-24 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 1.8E-24 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 Gene3D G3DSA:3.40.50.1370 135 303 1.6E-102 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 5 306 9.2E-108 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 152 305 1.0E-50 T 31-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 145 7.4E-42 T 31-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 SUPERFAMILY SSF53671 2 306 3.3E-89 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 81 94 1.9E-26 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 286 297 1.9E-26 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 48 62 1.9E-26 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 224 234 1.9E-26 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR86_09610 6bf73b595a06e2997ec0c5db2b5cc919 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 121 135 1.9E-26 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR86_01505 33942b93d845d421280dacead38ed112 282 SUPERFAMILY SSF52540 2 221 2.27E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01505 33942b93d845d421280dacead38ed112 282 Pfam PF00005 ABC transporter 18 154 3.9E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_01505 33942b93d845d421280dacead38ed112 282 Gene3D G3DSA:3.40.50.300 1 231 6.1E-53 T 31-10-2018 DFR86_01505 33942b93d845d421280dacead38ed112 282 SMART SM00382 27 202 2.8E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_08430 4e0431313ac6a3b118e746cc19f6bab9 389 Gene3D G3DSA:3.20.20.140 37 386 2.6E-64 T 31-10-2018 DFR86_08430 4e0431313ac6a3b118e746cc19f6bab9 389 Pfam PF01979 Amidohydrolase family 236 366 6.4E-7 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_08430 4e0431313ac6a3b118e746cc19f6bab9 389 Pfam PF01979 Amidohydrolase family 42 102 3.5E-6 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_08430 4e0431313ac6a3b118e746cc19f6bab9 389 SUPERFAMILY SSF51556 46 315 2.47E-54 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_08430 4e0431313ac6a3b118e746cc19f6bab9 389 ProSitePatterns PS00483 Dihydroorotase signature 2. 251 262 - T 31-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08430 4e0431313ac6a3b118e746cc19f6bab9 389 SUPERFAMILY SSF51338 315 377 2.84E-6 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_05150 eb0e3886ede49a9c96ab15ba234fa33d 315 Gene3D G3DSA:3.10.129.10 1 159 5.1E-32 T 31-10-2018 DFR86_05150 eb0e3886ede49a9c96ab15ba234fa33d 315 SUPERFAMILY SSF54637 166 311 2.21E-25 T 31-10-2018 IPR029069 HotDog domain superfamily DFR86_05150 eb0e3886ede49a9c96ab15ba234fa33d 315 Gene3D G3DSA:3.10.129.10 160 314 2.0E-30 T 31-10-2018 DFR86_05150 eb0e3886ede49a9c96ab15ba234fa33d 315 SUPERFAMILY SSF54637 3 144 9.86E-31 T 31-10-2018 IPR029069 HotDog domain superfamily DFR86_05150 eb0e3886ede49a9c96ab15ba234fa33d 315 Pfam PF03061 Thioesterase superfamily 189 255 1.1E-6 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR86_05150 eb0e3886ede49a9c96ab15ba234fa33d 315 Pfam PF03061 Thioesterase superfamily 22 96 9.2E-9 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR86_05305 795132b3085d4c2c789ca0dda6c61778 206 Pfam PF00227 Proteasome subunit 11 189 8.4E-47 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_05305 795132b3085d4c2c789ca0dda6c61778 206 Gene3D G3DSA:3.60.20.10 2 204 1.5E-55 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_05305 795132b3085d4c2c789ca0dda6c61778 206 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 12 194 1.3E-70 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 DFR86_05305 795132b3085d4c2c789ca0dda6c61778 206 PRINTS PR00141 Proteasome component signature 176 187 8.2E-10 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_05305 795132b3085d4c2c789ca0dda6c61778 206 PRINTS PR00141 Proteasome component signature 151 162 8.2E-10 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_05305 795132b3085d4c2c789ca0dda6c61778 206 PRINTS PR00141 Proteasome component signature 140 151 8.2E-10 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_05305 795132b3085d4c2c789ca0dda6c61778 206 PRINTS PR00141 Proteasome component signature 20 35 8.2E-10 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_05305 795132b3085d4c2c789ca0dda6c61778 206 SUPERFAMILY SSF56235 9 196 3.66E-54 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_05305 795132b3085d4c2c789ca0dda6c61778 206 Hamap MF_02113_A Proteasome subunit beta [prcB]. 8 203 33.429 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 DFR86_05305 795132b3085d4c2c789ca0dda6c61778 206 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 16 63 - T 31-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_01985 af923e730dcb7aa039ef260d7a309826 293 Pfam PF00535 Glycosyl transferase family 2 13 127 7.9E-9 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_01985 af923e730dcb7aa039ef260d7a309826 293 Gene3D G3DSA:3.90.550.10 2 189 1.2E-18 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_01985 af923e730dcb7aa039ef260d7a309826 293 SUPERFAMILY SSF53448 3 262 1.13E-24 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00155 9fd028bedbe7eee9a1b8333e9089533b 283 TIGRFAM TIGR02581 cas_cyan_RAMP: CRISPR-associated RAMP protein, SSO1426 family 13 228 5.9E-78 T 31-10-2018 IPR013411 CRISPR-associated RAMP TM1809 DFR86_00155 9fd028bedbe7eee9a1b8333e9089533b 283 Pfam PF03787 RAMP superfamily 22 222 4.3E-22 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_09770 ab87359f1f3e448489e453007bfbcad4 249 SUPERFAMILY SSF56300 25 241 1.4E-12 T 31-10-2018 DFR86_09770 ab87359f1f3e448489e453007bfbcad4 249 PIRSF PIRSF000887 3 248 7.7E-68 T 31-10-2018 IPR024173 Phosphoesterase, MJ0037 DFR86_09770 ab87359f1f3e448489e453007bfbcad4 249 Gene3D G3DSA:3.60.21.10 22 218 3.3E-10 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR86_09770 ab87359f1f3e448489e453007bfbcad4 249 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 23 242 6.9E-45 T 31-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like DFR86_02750 dd1a3bb4f2d19ce29d8037046ec702bc 416 SUPERFAMILY SSF53448 7 391 7.17E-57 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_02750 dd1a3bb4f2d19ce29d8037046ec702bc 416 Pfam PF00483 Nucleotidyl transferase 10 261 1.3E-38 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR86_02750 dd1a3bb4f2d19ce29d8037046ec702bc 416 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 361 394 0.0012 T 31-10-2018 IPR001451 Hexapeptide repeat DFR86_02750 dd1a3bb4f2d19ce29d8037046ec702bc 416 Gene3D G3DSA:3.90.550.10 2 279 1.0E-59 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_02750 dd1a3bb4f2d19ce29d8037046ec702bc 416 Gene3D G3DSA:2.160.10.10 284 374 2.4E-11 T 31-10-2018 DFR86_02750 dd1a3bb4f2d19ce29d8037046ec702bc 416 Gene3D G3DSA:2.160.10.10 375 416 1.1E-6 T 31-10-2018 DFR86_02750 dd1a3bb4f2d19ce29d8037046ec702bc 416 SUPERFAMILY SSF51161 305 407 3.27E-17 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 185 196 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Gene3D G3DSA:2.20.25.90 252 308 3.1E-15 T 31-10-2018 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 679 696 - T 31-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Pfam PF00037 4Fe-4S binding domain 179 200 6.2E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 252 307 9.2E-15 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Pfam PF01568 Molydopterin dinucleotide binding domain 817 924 8.5E-20 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 257 275 - T 31-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Gene3D G3DSA:3.30.70.20 123 203 7.1E-22 T 31-10-2018 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Gene3D G3DSA:2.40.40.20 806 935 3.5E-30 T 31-10-2018 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 SMART SM00926 252 307 7.0E-16 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 SUPERFAMILY SSF54862 74 207 5.02E-33 T 31-10-2018 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 81 118 1.6E-9 T 31-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Pfam PF00384 Molybdopterin oxidoreductase 310 733 1.5E-91 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Gene3D G3DSA:3.40.228.10 388 587 6.8E-178 T 31-10-2018 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 SUPERFAMILY SSF50692 790 929 1.83E-36 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Gene3D G3DSA:3.10.20.740 1 121 8.5E-32 T 31-10-2018 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 SUPERFAMILY SSF53706 252 818 5.63E-201 T 31-10-2018 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Gene3D G3DSA:3.40.50.740 315 776 6.8E-178 T 31-10-2018 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 SMART SM00929 81 121 2.2E-7 T 31-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 74 8.7E-10 T 31-10-2018 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 PIRSF PIRSF036643 1 962 0.0 T 31-10-2018 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 SUPERFAMILY SSF54292 1 71 1.85E-14 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR86_03860 d9d65c5bbb958c55640fd4f7432ba252 973 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 257 927 7.4E-272 T 31-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 DFR86_09030 c6b52b07af2a8196414d70b38fd4e2e9 413 Gene3D G3DSA:3.30.460.10 13 140 3.3E-89 T 31-10-2018 DFR86_09030 c6b52b07af2a8196414d70b38fd4e2e9 413 Gene3D G3DSA:1.10.1410.30 6 253 3.3E-89 T 31-10-2018 DFR86_09030 c6b52b07af2a8196414d70b38fd4e2e9 413 Hamap MF_01264 CCA-adding enzyme [cca]. 1 413 134.671 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 DFR86_09030 c6b52b07af2a8196414d70b38fd4e2e9 413 Pfam PF01909 Nucleotidyltransferase domain 29 129 3.9E-16 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR86_09030 c6b52b07af2a8196414d70b38fd4e2e9 413 SUPERFAMILY SSF81631 142 254 1.37E-38 T 31-10-2018 DFR86_09030 c6b52b07af2a8196414d70b38fd4e2e9 413 SUPERFAMILY SSF55003 239 412 2.12E-36 T 31-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 DFR86_09030 c6b52b07af2a8196414d70b38fd4e2e9 413 PIRSF PIRSF005335 1 408 9.1E-137 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 DFR86_09030 c6b52b07af2a8196414d70b38fd4e2e9 413 SUPERFAMILY SSF81301 3 138 7.3E-32 T 31-10-2018 DFR86_09030 c6b52b07af2a8196414d70b38fd4e2e9 413 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 4 380 4.5E-132 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 DFR86_09030 c6b52b07af2a8196414d70b38fd4e2e9 413 Pfam PF09249 tRNA nucleotidyltransferase, second domain 144 253 2.9E-43 T 31-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 DFR86_05515 ea1d8677aca33a217ae02c666d8f1ac5 152 SUPERFAMILY SSF53335 8 122 1.63E-15 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_05515 ea1d8677aca33a217ae02c666d8f1ac5 152 Gene3D G3DSA:3.40.50.150 1 152 4.3E-23 T 31-10-2018 DFR86_05515 ea1d8677aca33a217ae02c666d8f1ac5 152 Pfam PF08123 Histone methylation protein DOT1 10 67 3.5E-5 T 31-10-2018 IPR025789 Histone-lysine N-methyltransferase DOT1 domain GO:0018024 KEGG: 00310+2.1.1.43|Reactome: R-HSA-3214841 DFR86_05440 ae299a907d070956dacb577816146493 409 Gene3D G3DSA:3.30.390.30 300 408 6.5E-22 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_05440 ae299a907d070956dacb577816146493 409 Gene3D G3DSA:3.50.50.60 4 290 1.5E-61 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05440 ae299a907d070956dacb577816146493 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 7.8E-33 T 31-10-2018 DFR86_05440 ae299a907d070956dacb577816146493 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 49 7.8E-33 T 31-10-2018 DFR86_05440 ae299a907d070956dacb577816146493 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 7.8E-33 T 31-10-2018 DFR86_05440 ae299a907d070956dacb577816146493 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 7.8E-33 T 31-10-2018 DFR86_05440 ae299a907d070956dacb577816146493 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 323 7.8E-33 T 31-10-2018 DFR86_05440 ae299a907d070956dacb577816146493 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 286 3.4E-47 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_05440 ae299a907d070956dacb577816146493 409 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 35 45 - T 31-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 DFR86_05440 ae299a907d070956dacb577816146493 409 SUPERFAMILY SSF51905 2 296 3.24E-39 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05440 ae299a907d070956dacb577816146493 409 Gene3D G3DSA:3.50.50.60 132 237 1.5E-61 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05440 ae299a907d070956dacb577816146493 409 SUPERFAMILY SSF55424 305 407 2.41E-21 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_05440 ae299a907d070956dacb577816146493 409 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 306 403 2.8E-15 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR86_05440 ae299a907d070956dacb577816146493 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 5.1E-26 T 31-10-2018 DFR86_05440 ae299a907d070956dacb577816146493 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 5.1E-26 T 31-10-2018 DFR86_05440 ae299a907d070956dacb577816146493 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 5.1E-26 T 31-10-2018 DFR86_05440 ae299a907d070956dacb577816146493 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 138 5.1E-26 T 31-10-2018 DFR86_05440 ae299a907d070956dacb577816146493 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 5.1E-26 T 31-10-2018 DFR86_09145 44609a59b0006033b3b23f873fe0263a 211 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 77 93 - T 31-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 DFR86_09145 44609a59b0006033b3b23f873fe0263a 211 SUPERFAMILY SSF55620 3 202 3.19E-61 T 31-10-2018 DFR86_09145 44609a59b0006033b3b23f873fe0263a 211 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 10 201 35.885 T 31-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 DFR86_09145 44609a59b0006033b3b23f873fe0263a 211 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 127 137 - T 31-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 DFR86_09145 44609a59b0006033b3b23f873fe0263a 211 Pfam PF01227 GTP cyclohydrolase I 14 200 1.5E-65 T 31-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 DFR86_09145 44609a59b0006033b3b23f873fe0263a 211 Gene3D G3DSA:1.10.286.10 2 57 2.8E-17 T 31-10-2018 DFR86_09145 44609a59b0006033b3b23f873fe0263a 211 Gene3D G3DSA:3.30.1130.10 69 203 1.6E-44 T 31-10-2018 DFR86_05535 537c2edf9404a202376db3d639985943 55 SMART SM00966 8 55 2.7E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_05535 537c2edf9404a202376db3d639985943 55 Gene3D G3DSA:2.10.260.10 2 49 5.3E-19 T 31-10-2018 DFR86_05535 537c2edf9404a202376db3d639985943 55 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 52 1.5E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_05535 537c2edf9404a202376db3d639985943 55 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 7 47 8.6E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_05535 537c2edf9404a202376db3d639985943 55 SUPERFAMILY SSF89447 3 43 9.59E-11 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR86_01330 22c5542da9415f66189656918fe6940e 307 SUPERFAMILY SSF56327 140 295 4.62E-31 T 31-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DFR86_01330 22c5542da9415f66189656918fe6940e 307 PIRSF PIRSF000102 1 303 1.3E-75 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DFR86_01330 22c5542da9415f66189656918fe6940e 307 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 2 134 1.5E-30 T 31-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 DFR86_01330 22c5542da9415f66189656918fe6940e 307 SUPERFAMILY SSF51735 3 134 8.58E-35 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_01330 22c5542da9415f66189656918fe6940e 307 Gene3D G3DSA:3.40.50.720 1 141 2.7E-34 T 31-10-2018 DFR86_01330 22c5542da9415f66189656918fe6940e 307 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 8.2E-15 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DFR86_01330 22c5542da9415f66189656918fe6940e 307 PRINTS PR00086 L-lactate dehydrogenase signature 137 155 8.2E-15 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DFR86_01330 22c5542da9415f66189656918fe6940e 307 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 8.2E-15 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DFR86_01330 22c5542da9415f66189656918fe6940e 307 PRINTS PR00086 L-lactate dehydrogenase signature 167 180 8.2E-15 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DFR86_01330 22c5542da9415f66189656918fe6940e 307 Gene3D G3DSA:3.90.110.10 142 296 6.9E-29 T 31-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DFR86_01815 730f450c955fe44d960868f83e568e87 522 SUPERFAMILY SSF52096 249 522 2.49E-90 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR86_01815 730f450c955fe44d960868f83e568e87 522 Gene3D G3DSA:3.90.226.10 2 265 1.6E-92 T 31-10-2018 DFR86_01815 730f450c955fe44d960868f83e568e87 522 Pfam PF01039 Carboxyl transferase domain 34 520 6.7E-182 T 31-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 DFR86_01815 730f450c955fe44d960868f83e568e87 522 Gene3D G3DSA:3.90.226.10 266 522 1.1E-92 T 31-10-2018 DFR86_01815 730f450c955fe44d960868f83e568e87 522 SUPERFAMILY SSF52096 7 262 7.26E-74 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 SUPERFAMILY SSF50974 99 231 1.83E-16 T 31-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 SUPERFAMILY SSF50974 232 486 1.1E-35 T 31-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 320 353 3.1E-9 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 377 416 1.8E-7 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 182 219 7.0E-11 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 278 315 2.4E-11 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 420 461 2.5E-13 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 140 177 2.7E-7 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 Gene3D G3DSA:2.130.10.10 246 370 3.5E-25 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 Gene3D G3DSA:2.130.10.10 372 508 1.0E-22 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_11735 896130e1e11f9ac6e94aed8a82d1bf2f 529 Gene3D G3DSA:2.130.10.10 77 237 2.3E-21 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_08995 d66742990be7ee68ad34bb8112fdd3b4 254 Pfam PF03029 Conserved hypothetical ATP binding protein 7 239 8.2E-57 T 31-10-2018 IPR004130 GPN-loop GTPase DFR86_08995 d66742990be7ee68ad34bb8112fdd3b4 254 SUPERFAMILY SSF52540 3 238 5.26E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08995 d66742990be7ee68ad34bb8112fdd3b4 254 Gene3D G3DSA:3.40.50.300 1 252 3.0E-62 T 31-10-2018 DFR86_06155 9ae2e32abf6ad4e605236057724f2c13 555 Gene3D G3DSA:3.40.50.300 352 550 3.0E-18 T 31-10-2018 DFR86_06155 9ae2e32abf6ad4e605236057724f2c13 555 Pfam PF01935 Domain of unknown function DUF87 242 426 2.1E-6 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR86_06155 9ae2e32abf6ad4e605236057724f2c13 555 SUPERFAMILY SSF52540 225 524 3.14E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06155 9ae2e32abf6ad4e605236057724f2c13 555 Gene3D G3DSA:3.40.50.300 207 329 5.6E-8 T 31-10-2018 DFR86_04175 68205b62dc6df1de07ea030a7220d959 304 Pfam PF00491 Arginase family 32 295 3.1E-79 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 DFR86_04175 68205b62dc6df1de07ea030a7220d959 304 SUPERFAMILY SSF52768 10 300 1.98E-88 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily DFR86_04175 68205b62dc6df1de07ea030a7220d959 304 PIRSF PIRSF036979 7 304 2.2E-102 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 DFR86_04175 68205b62dc6df1de07ea030a7220d959 304 ProSitePatterns PS01053 Arginase family signature. 229 250 - T 31-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 DFR86_04175 68205b62dc6df1de07ea030a7220d959 304 TIGRFAM TIGR01230 agmatinase: agmatinase 26 297 7.0E-68 T 31-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 DFR86_04175 68205b62dc6df1de07ea030a7220d959 304 Gene3D G3DSA:3.40.800.10 1 303 1.0E-100 T 31-10-2018 DFR86_07350 926a17c485537ff45ed2bc0af2783508 322 Pfam PF00756 Putative esterase 101 307 1.0E-12 T 31-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 DFR86_07350 926a17c485537ff45ed2bc0af2783508 322 SUPERFAMILY SSF53474 22 315 5.05E-27 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_00505 65794614d14abdf4b7e8762503d440cb 396 SUPERFAMILY SSF52518 4 246 6.22E-67 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_00505 65794614d14abdf4b7e8762503d440cb 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 17 237 3.8E-68 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DFR86_00505 65794614d14abdf4b7e8762503d440cb 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 263 359 2.2E-23 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II DFR86_00505 65794614d14abdf4b7e8762503d440cb 396 Gene3D G3DSA:3.40.50.920 254 381 1.5E-30 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR86_00505 65794614d14abdf4b7e8762503d440cb 396 Gene3D G3DSA:3.40.50.970 2 247 5.8E-96 T 31-10-2018 DFR86_00505 65794614d14abdf4b7e8762503d440cb 396 SUPERFAMILY SSF52922 254 372 5.71E-29 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR86_09790 a23ca97b7759e82774cbede3d492542a 359 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 16 319 47.553 T 31-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 DFR86_09790 a23ca97b7759e82774cbede3d492542a 359 Gene3D G3DSA:3.20.20.70 13 327 1.8E-114 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_09790 a23ca97b7759e82774cbede3d492542a 359 Pfam PF04055 Radical SAM superfamily 69 251 2.0E-20 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_09790 a23ca97b7759e82774cbede3d492542a 359 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 17 318 4.8E-131 T 31-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 DFR86_09790 a23ca97b7759e82774cbede3d492542a 359 SUPERFAMILY SSF102114 72 305 3.66E-15 T 31-10-2018 DFR86_09790 a23ca97b7759e82774cbede3d492542a 359 Pfam PF08608 Wyosine base formation 259 319 5.9E-21 T 31-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 DFR86_10400 8aca4c77c3dd22c140ab2964a7a966b6 215 SMART SM00987 41 204 2.3E-29 T 31-10-2018 DFR86_10400 8aca4c77c3dd22c140ab2964a7a966b6 215 SMART SM00986 41 204 2.3E-29 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR86_10400 8aca4c77c3dd22c140ab2964a7a966b6 215 Pfam PF03167 Uracil DNA glycosylase superfamily 41 203 3.0E-36 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR86_10400 8aca4c77c3dd22c140ab2964a7a966b6 215 Gene3D G3DSA:3.40.470.10 1 211 1.2E-65 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR86_10400 8aca4c77c3dd22c140ab2964a7a966b6 215 SUPERFAMILY SSF52141 9 207 8.18E-48 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 SUPERFAMILY SSF51735 185 419 3.18E-70 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 104 117 - T 31-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 PIRSF PIRSF000185 6 420 9.2E-159 T 31-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 SUPERFAMILY SSF53223 9 187 6.4E-64 T 31-10-2018 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 Gene3D G3DSA:3.40.50.10860 41 184 1.0E-58 T 31-10-2018 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 185 418 5.5E-71 T 31-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 SMART SM00839 187 418 7.7E-85 T 31-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 198 3.6E-30 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 345 356 3.6E-30 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 218 238 3.6E-30 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 96 110 3.6E-30 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 Gene3D G3DSA:3.40.50.720 185 420 2.3E-81 T 31-10-2018 DFR86_05200 95d30addeffefacf9ad343ba8d250319 420 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 39 166 1.1E-53 T 31-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR86_05330 b3812de24358d0467f2980a740f66c52 77 SUPERFAMILY SSF46785 2 65 2.02E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_05330 b3812de24358d0467f2980a740f66c52 77 Gene3D G3DSA:1.10.10.10 1 77 2.1E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10445 b7366c399b0b1b275cefc2f5908f0e82 178 SUPERFAMILY SSF102405 2 165 3.05E-21 T 31-10-2018 DFR86_10445 b7366c399b0b1b275cefc2f5908f0e82 178 Gene3D G3DSA:3.40.50.450 4 166 7.8E-20 T 31-10-2018 DFR86_02905 c836f46dc96ebdf530e6cf26e1a06110 450 Gene3D G3DSA:1.10.8.60 360 450 1.3E-27 T 31-10-2018 DFR86_02905 c836f46dc96ebdf530e6cf26e1a06110 450 Gene3D G3DSA:2.40.50.360 120 245 1.1E-103 T 31-10-2018 DFR86_02905 c836f46dc96ebdf530e6cf26e1a06110 450 SMART SM00382 63 359 2.4E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_02905 c836f46dc96ebdf530e6cf26e1a06110 450 Gene3D G3DSA:3.40.50.300 19 355 1.1E-103 T 31-10-2018 DFR86_02905 c836f46dc96ebdf530e6cf26e1a06110 450 Pfam PF06068 TIP49 C-terminus 16 409 9.6E-153 T 31-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 DFR86_02905 c836f46dc96ebdf530e6cf26e1a06110 450 SUPERFAMILY SSF52540 37 431 3.61E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_05795 e09b70b26a6de4d5b88a15c755b67613 182 Pfam PF01479 S4 domain 104 149 2.5E-15 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05795 e09b70b26a6de4d5b88a15c755b67613 182 SMART SM00363 104 166 2.3E-12 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05795 e09b70b26a6de4d5b88a15c755b67613 182 SMART SM01390 5 103 1.1E-17 T 31-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 DFR86_05795 e09b70b26a6de4d5b88a15c755b67613 182 SUPERFAMILY SSF55174 9 164 2.89E-29 T 31-10-2018 DFR86_05795 e09b70b26a6de4d5b88a15c755b67613 182 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 157 32.537 T 31-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 DFR86_05795 e09b70b26a6de4d5b88a15c755b67613 182 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 9.4E-67 T 31-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05795 e09b70b26a6de4d5b88a15c755b67613 182 ProSitePatterns PS00632 Ribosomal protein S4 signature. 102 126 - T 31-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05795 e09b70b26a6de4d5b88a15c755b67613 182 Gene3D G3DSA:3.10.290.10 103 180 3.4E-16 T 31-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 DFR86_09540 61af0fd8a67cacf063665116f2be6f24 245 SUPERFAMILY SSF51366 4 242 8.38E-53 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR86_09540 61af0fd8a67cacf063665116f2be6f24 245 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 2 233 2.5E-35 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_09540 61af0fd8a67cacf063665116f2be6f24 245 Pfam PF00290 Tryptophan synthase alpha chain 4 231 8.4E-37 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_09540 61af0fd8a67cacf063665116f2be6f24 245 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 35 48 - T 31-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_09540 61af0fd8a67cacf063665116f2be6f24 245 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 1 241 25.424 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_09540 61af0fd8a67cacf063665116f2be6f24 245 Gene3D G3DSA:3.20.20.70 2 243 1.9E-50 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_02650 c1ca99c5e5032f40c62be7ff9f1e0d38 314 Gene3D G3DSA:3.40.50.10800 89 307 1.0E-105 T 31-10-2018 DFR86_02650 c1ca99c5e5032f40c62be7ff9f1e0d38 314 Hamap MF_00568 Quinolinate synthase A [nadA]. 5 309 43.216 T 31-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 DFR86_02650 c1ca99c5e5032f40c62be7ff9f1e0d38 314 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 6 309 1.8E-99 T 31-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 DFR86_02650 c1ca99c5e5032f40c62be7ff9f1e0d38 314 Gene3D G3DSA:3.40.50.10800 9 290 1.0E-105 T 31-10-2018 DFR86_02650 c1ca99c5e5032f40c62be7ff9f1e0d38 314 SUPERFAMILY SSF142754 6 308 2.75E-103 T 31-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 DFR86_02650 c1ca99c5e5032f40c62be7ff9f1e0d38 314 Pfam PF02445 Quinolinate synthetase A protein 9 307 7.5E-105 T 31-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 DFR86_02650 c1ca99c5e5032f40c62be7ff9f1e0d38 314 Gene3D G3DSA:3.40.50.10800 174 265 1.0E-105 T 31-10-2018 DFR86_03390 79cb922f930efca04a2122644ed7e09a 268 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 9 246 6.4E-101 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 DFR86_03390 79cb922f930efca04a2122644ed7e09a 268 SUPERFAMILY SSF53167 7 267 7.59E-95 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 DFR86_03390 79cb922f930efca04a2122644ed7e09a 268 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 7 268 44.061 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 DFR86_03390 79cb922f930efca04a2122644ed7e09a 268 Pfam PF01048 Phosphorylase superfamily 8 245 3.6E-49 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DFR86_03390 79cb922f930efca04a2122644ed7e09a 268 Gene3D G3DSA:3.40.50.1580 2 268 1.7E-102 T 31-10-2018 DFR86_03390 79cb922f930efca04a2122644ed7e09a 268 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 55 95 - T 31-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 DFR86_02185 2f1c7a30f6d5ee1a36bd383981edd460 538 Pfam PF01935 Domain of unknown function DUF87 132 380 5.8E-36 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR86_02185 2f1c7a30f6d5ee1a36bd383981edd460 538 Gene3D G3DSA:3.40.50.300 116 314 3.8E-16 T 31-10-2018 DFR86_02185 2f1c7a30f6d5ee1a36bd383981edd460 538 Gene3D G3DSA:3.40.50.300 321 517 5.0E-34 T 31-10-2018 DFR86_02185 2f1c7a30f6d5ee1a36bd383981edd460 538 SUPERFAMILY SSF52540 129 516 5.91E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_10360 22c3a22e73906f93e6a81b00217c7e74 381 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 293 5.9E-17 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_10360 22c3a22e73906f93e6a81b00217c7e74 381 Gene3D G3DSA:3.50.50.100 2 379 1.3E-59 T 31-10-2018 DFR86_10360 22c3a22e73906f93e6a81b00217c7e74 381 SUPERFAMILY SSF51905 2 309 3.29E-19 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_10360 22c3a22e73906f93e6a81b00217c7e74 381 SUPERFAMILY SSF51905 117 244 3.59E-7 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_06845 e526504903a3df64b89a150c69ad6246 133 Pfam PF00410 Ribosomal protein S8 5 133 1.9E-20 T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06845 e526504903a3df64b89a150c69ad6246 133 Gene3D G3DSA:3.30.1370.30 1 69 2.8E-27 T 31-10-2018 DFR86_06845 e526504903a3df64b89a150c69ad6246 133 Gene3D G3DSA:3.30.1490.10 70 131 4.6E-22 T 31-10-2018 DFR86_06845 e526504903a3df64b89a150c69ad6246 133 SUPERFAMILY SSF56047 4 133 2.35E-32 T 31-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06845 e526504903a3df64b89a150c69ad6246 133 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 133 32.759 T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06845 e526504903a3df64b89a150c69ad6246 133 ProSitePatterns PS00053 Ribosomal protein S8 signature. 103 120 - T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09405 ebf94be69b064b14a7213f7766c35b62 500 Gene3D G3DSA:3.40.640.10 90 319 9.0E-57 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_09405 ebf94be69b064b14a7213f7766c35b62 500 SUPERFAMILY SSF53383 29 476 1.77E-103 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_09405 ebf94be69b064b14a7213f7766c35b62 500 Gene3D G3DSA:3.90.1150.10 336 470 1.9E-37 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_09405 ebf94be69b064b14a7213f7766c35b62 500 Pfam PF02347 Glycine cleavage system P-protein 33 366 7.3E-16 T 31-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 DFR86_02340 6c94613b48771d5fbe45dcb37474b5b1 356 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 129 2.0E-31 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR86_02340 6c94613b48771d5fbe45dcb37474b5b1 356 SUPERFAMILY SSF55347 148 336 5.06E-35 T 31-10-2018 DFR86_02340 6c94613b48771d5fbe45dcb37474b5b1 356 Gene3D G3DSA:3.30.360.10 150 332 1.3E-130 T 31-10-2018 DFR86_02340 6c94613b48771d5fbe45dcb37474b5b1 356 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 334 1.3E-20 T 31-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR86_02340 6c94613b48771d5fbe45dcb37474b5b1 356 SUPERFAMILY SSF51735 5 177 2.44E-38 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_02340 6c94613b48771d5fbe45dcb37474b5b1 356 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 5 349 2.0E-106 T 31-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 DFR86_02340 6c94613b48771d5fbe45dcb37474b5b1 356 Gene3D G3DSA:3.40.50.720 6 352 1.3E-130 T 31-10-2018 DFR86_02340 6c94613b48771d5fbe45dcb37474b5b1 356 SMART SM00859 6 131 9.6E-34 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR86_02340 6c94613b48771d5fbe45dcb37474b5b1 356 PIRSF PIRSF000148 4 354 1.3E-84 T 31-10-2018 DFR86_07780 89d00a2ebc7963e3f50d9b58d922d435 138 Pfam PF13673 Acetyltransferase (GNAT) domain 17 114 3.0E-11 T 31-10-2018 IPR000182 GNAT domain DFR86_07780 89d00a2ebc7963e3f50d9b58d922d435 138 SUPERFAMILY SSF55729 14 107 3.73E-13 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR86_07780 89d00a2ebc7963e3f50d9b58d922d435 138 Gene3D G3DSA:3.40.630.30 3 115 8.8E-15 T 31-10-2018 DFR86_08750 1ca92e0513b8582985a903fc63c3035e 392 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 45 56 - T 31-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08750 1ca92e0513b8582985a903fc63c3035e 392 Gene3D G3DSA:1.10.645.20 10 392 1.2E-131 T 31-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08750 1ca92e0513b8582985a903fc63c3035e 392 SUPERFAMILY SSF56762 22 392 3.79E-110 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08750 1ca92e0513b8582985a903fc63c3035e 392 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 123 392 4.7E-92 T 31-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 SUPERFAMILY SSF52540 170 418 3.11E-71 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 Gene3D G3DSA:1.10.8.60 602 677 3.5E-93 T 31-10-2018 DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 Gene3D G3DSA:1.10.8.60 341 424 2.5E-25 T 31-10-2018 DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 SMART SM00382 206 342 9.5E-25 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 SMART SM00382 466 603 6.2E-22 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 Gene3D G3DSA:3.40.50.300 428 692 3.5E-93 T 31-10-2018 DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 SUPERFAMILY SSF52540 428 694 1.47E-67 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 ProSitePatterns PS00674 AAA-protein family signature. 310 328 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 339 1.3E-48 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 470 600 4.9E-47 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_04710 79d88aa6c2201ee1ba0f8959f66cad87 703 Gene3D G3DSA:3.40.50.300 159 340 9.4E-68 T 31-10-2018 DFR86_10505 64bed16529bd46585076d1bc1e7c0f24 534 SUPERFAMILY SSF53649 171 368 7.2E-7 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 DFR86_10505 64bed16529bd46585076d1bc1e7c0f24 534 Gene3D G3DSA:3.40.720.10 34 209 9.2E-22 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR86_10505 64bed16529bd46585076d1bc1e7c0f24 534 Gene3D G3DSA:3.40.720.10 279 428 2.7E-32 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR86_10505 64bed16529bd46585076d1bc1e7c0f24 534 Pfam PF04185 Phosphoesterase family 44 386 3.4E-71 T 31-10-2018 IPR007312 Phosphoesterase GO:0016788 DFR86_07665 eb7448f36fb139871f767138aa2ffb85 584 Pfam PF01935 Domain of unknown function DUF87 161 423 3.5E-22 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR86_07665 eb7448f36fb139871f767138aa2ffb85 584 SUPERFAMILY SSF52540 157 535 1.03E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07665 eb7448f36fb139871f767138aa2ffb85 584 Gene3D G3DSA:3.40.50.300 345 569 1.3E-23 T 31-10-2018 DFR86_07665 eb7448f36fb139871f767138aa2ffb85 584 Gene3D G3DSA:3.40.50.300 147 287 3.5E-18 T 31-10-2018 DFR86_08055 ca2ae3ed583a528767c74ee79277ba92 381 Gene3D G3DSA:3.40.640.10 60 277 2.2E-91 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_08055 ca2ae3ed583a528767c74ee79277ba92 381 SUPERFAMILY SSF53383 15 377 1.1E-78 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_08055 ca2ae3ed583a528767c74ee79277ba92 381 Gene3D G3DSA:3.90.1150.10 19 377 2.2E-91 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_08055 ca2ae3ed583a528767c74ee79277ba92 381 Pfam PF00155 Aminotransferase class I and II 24 370 1.9E-27 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR86_06305 5df984874d71118c99ec35521d2b4c89 211 Pfam PF01872 RibD C-terminal domain 4 207 3.8E-43 T 31-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 DFR86_06305 5df984874d71118c99ec35521d2b4c89 211 TIGRFAM TIGR01508 rib_reduct_arch: diaminohydroxyphosphoribosylaminopyrimidine reductase 3 208 1.7E-65 T 31-10-2018 IPR006401 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal GO:0016491|GO:0055114 KEGG: 00740+1.1.1.302|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_06305 5df984874d71118c99ec35521d2b4c89 211 Gene3D G3DSA:3.40.430.10 4 211 4.3E-47 T 31-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 DFR86_06305 5df984874d71118c99ec35521d2b4c89 211 SUPERFAMILY SSF53597 4 201 6.81E-42 T 31-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 Gene3D G3DSA:1.10.10.10 293 384 9.3E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 Hamap MF_01407 ORC1-type DNA replication protein. 7 374 24.245 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 25 360 3.4E-73 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 Gene3D G3DSA:3.40.50.300 39 206 9.2E-80 T 31-10-2018 DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 Pfam PF13401 AAA domain 60 181 6.6E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 SMART SM00382 53 203 4.8E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 SUPERFAMILY SSF46785 283 377 1.22E-19 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 SMART SM01074 299 374 6.9E-17 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 Pfam PF09079 CDC6, C terminal winged helix domain 311 366 3.7E-12 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 Gene3D G3DSA:1.10.8.60 207 286 9.2E-80 T 31-10-2018 DFR86_02310 4260e7595b51cc7bd33978de1a3751a1 386 SUPERFAMILY SSF52540 23 265 4.11E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03370 ef91395cef6a638fb01375327921ff51 159 SMART SM00344 7 113 1.4E-42 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR86_03370 ef91395cef6a638fb01375327921ff51 159 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 4.1E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_03370 ef91395cef6a638fb01375327921ff51 159 SUPERFAMILY SSF46785 5 66 2.86E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_03370 ef91395cef6a638fb01375327921ff51 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 5.8E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_03370 ef91395cef6a638fb01375327921ff51 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 5.8E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_03370 ef91395cef6a638fb01375327921ff51 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 5.8E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_03370 ef91395cef6a638fb01375327921ff51 159 Gene3D G3DSA:3.30.70.920 60 150 6.4E-23 T 31-10-2018 DFR86_03370 ef91395cef6a638fb01375327921ff51 159 Pfam PF01037 Lrp/AsnC ligand binding domain 74 143 2.1E-16 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR86_03370 ef91395cef6a638fb01375327921ff51 159 SUPERFAMILY SSF54909 68 147 1.47E-18 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR86_03370 ef91395cef6a638fb01375327921ff51 159 Gene3D G3DSA:1.10.10.10 5 57 5.8E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_02455 5724b30403ffd4c48a36718f6e9f0fc8 237 SUPERFAMILY SSF47240 1 128 5.68E-16 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR86_02455 5724b30403ffd4c48a36718f6e9f0fc8 237 Gene3D G3DSA:1.20.1260.10 125 237 1.8E-7 T 31-10-2018 IPR012347 Ferritin-like DFR86_02455 5724b30403ffd4c48a36718f6e9f0fc8 237 Gene3D G3DSA:1.20.1260.10 3 124 4.8E-8 T 31-10-2018 IPR012347 Ferritin-like DFR86_02455 5724b30403ffd4c48a36718f6e9f0fc8 237 SUPERFAMILY SSF47240 142 236 1.88E-11 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 12 459 2.8E-69 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 PRINTS PR01165 Cytochrome c oxidase subunit I signature 127 139 4.3E-23 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 PRINTS PR01165 Cytochrome c oxidase subunit I signature 332 350 4.3E-23 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 PRINTS PR01165 Cytochrome c oxidase subunit I signature 52 75 4.3E-23 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 PRINTS PR01165 Cytochrome c oxidase subunit I signature 272 287 4.3E-23 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 PRINTS PR01165 Cytochrome c oxidase subunit I signature 418 439 4.3E-23 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 PRINTS PR01165 Cytochrome c oxidase subunit I signature 360 379 4.3E-23 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 PRINTS PR01165 Cytochrome c oxidase subunit I signature 296 317 4.3E-23 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 PRINTS PR01165 Cytochrome c oxidase subunit I signature 226 247 4.3E-23 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 Gene3D G3DSA:1.20.210.10 10 495 2.6E-70 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 228 282 - T 31-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01170 63982d285119607b06bfb7922b1fe4a7 519 SUPERFAMILY SSF81442 11 486 3.53E-70 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_09980 604755b5cd76e2f99bdd703ccfe72a22 84 SUPERFAMILY SSF46785 13 79 4.48E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_09980 604755b5cd76e2f99bdd703ccfe72a22 84 Gene3D G3DSA:1.10.10.10 2 82 1.9E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_08870 cb6262fda4044e47668054d0cbeb94b5 312 SUPERFAMILY SSF52922 177 311 1.96E-33 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR86_08870 cb6262fda4044e47668054d0cbeb94b5 312 SMART SM00861 7 172 2.0E-50 T 31-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain DFR86_08870 cb6262fda4044e47668054d0cbeb94b5 312 Pfam PF02779 Transketolase, pyrimidine binding domain 8 166 2.2E-38 T 31-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain DFR86_08870 cb6262fda4044e47668054d0cbeb94b5 312 Pfam PF02780 Transketolase, C-terminal domain 183 303 1.2E-27 T 31-10-2018 IPR033248 Transketolase, C-terminal domain DFR86_08870 cb6262fda4044e47668054d0cbeb94b5 312 Gene3D G3DSA:3.40.50.970 5 180 2.2E-59 T 31-10-2018 DFR86_08870 cb6262fda4044e47668054d0cbeb94b5 312 Gene3D G3DSA:3.40.50.920 183 312 2.6E-36 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR86_08870 cb6262fda4044e47668054d0cbeb94b5 312 SUPERFAMILY SSF52518 8 171 1.31E-52 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_05930 a371e40584332fa15f0cfabf5a211f55 211 Gene3D G3DSA:1.20.58.220 70 207 3.2E-14 T 31-10-2018 IPR038078 PhoU-like domain superfamily DFR86_05930 a371e40584332fa15f0cfabf5a211f55 211 SUPERFAMILY SSF109755 3 206 1.31E-8 T 31-10-2018 DFR86_05930 a371e40584332fa15f0cfabf5a211f55 211 Pfam PF01865 Protein of unknown function DUF47 83 206 5.7E-5 T 31-10-2018 IPR018445 Putative phosphate transport regulator DFR86_08425 a4f3b5aeb3a0fa6d177b3a3740d854a6 199 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 170 178 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DFR86_08315 9c6207ae71949fc2190889a02aa1bdbf 322 Gene3D G3DSA:3.30.1330.10 1 157 2.4E-43 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_08315 9c6207ae71949fc2190889a02aa1bdbf 322 Gene3D G3DSA:3.90.650.10 158 317 1.6E-46 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_08315 9c6207ae71949fc2190889a02aa1bdbf 322 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 315 33.771 T 31-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR86_08315 9c6207ae71949fc2190889a02aa1bdbf 322 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 306 1.6E-91 T 31-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR86_08315 9c6207ae71949fc2190889a02aa1bdbf 322 Pfam PF02769 AIR synthase related protein, C-terminal domain 163 312 3.7E-27 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR86_08315 9c6207ae71949fc2190889a02aa1bdbf 322 SUPERFAMILY SSF56042 158 312 1.11E-38 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_08315 9c6207ae71949fc2190889a02aa1bdbf 322 SUPERFAMILY SSF55326 4 155 2.54E-35 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_08315 9c6207ae71949fc2190889a02aa1bdbf 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 51 153 7.8E-17 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR86_05110 687d4c42794cd04b561351cfc61ef51c 523 Pfam PF00682 HMGL-like 5 275 2.7E-56 T 31-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 DFR86_05110 687d4c42794cd04b561351cfc61ef51c 523 SMART SM00917 374 507 3.9E-25 T 31-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR86_05110 687d4c42794cd04b561351cfc61ef51c 523 Pfam PF08502 LeuA allosteric (dimerisation) domain 376 506 2.0E-20 T 31-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR86_05110 687d4c42794cd04b561351cfc61ef51c 523 SUPERFAMILY SSF110921 403 505 1.44E-11 T 31-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR86_05110 687d4c42794cd04b561351cfc61ef51c 523 Gene3D G3DSA:3.20.20.70 3 281 6.0E-85 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_05110 687d4c42794cd04b561351cfc61ef51c 523 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 7 510 1.2E-194 T 31-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 DFR86_05110 687d4c42794cd04b561351cfc61ef51c 523 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 202 215 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR86_05110 687d4c42794cd04b561351cfc61ef51c 523 Gene3D G3DSA:1.10.238.260 284 394 1.8E-26 T 31-10-2018 DFR86_05110 687d4c42794cd04b561351cfc61ef51c 523 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR86_05110 687d4c42794cd04b561351cfc61ef51c 523 SUPERFAMILY SSF51569 5 293 3.85E-83 T 31-10-2018 DFR86_07990 b90d2f021081432cdfe705330438b2a4 517 Gene3D G3DSA:1.20.1740.10 8 386 1.7E-25 T 31-10-2018 DFR86_07990 b90d2f021081432cdfe705330438b2a4 517 PIRSF PIRSF006060 4 516 5.4E-65 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_07990 b90d2f021081432cdfe705330438b2a4 517 Pfam PF13520 Amino acid permease 40 482 6.0E-27 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_06695 ea7db6c3b8a0d9b25c187f69b0ace2f3 247 Gene3D G3DSA:2.40.50.140 68 153 3.7E-22 T 31-10-2018 DFR86_06695 ea7db6c3b8a0d9b25c187f69b0ace2f3 247 Gene3D G3DSA:3.30.1370.10 156 247 4.5E-33 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 DFR86_06695 ea7db6c3b8a0d9b25c187f69b0ace2f3 247 Gene3D G3DSA:2.40.50.100 2 66 3.8E-22 T 31-10-2018 DFR86_06695 ea7db6c3b8a0d9b25c187f69b0ace2f3 247 SUPERFAMILY SSF50249 69 159 3.1E-20 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_06695 ea7db6c3b8a0d9b25c187f69b0ace2f3 247 SUPERFAMILY SSF110324 10 67 4.71E-14 T 31-10-2018 DFR86_06695 ea7db6c3b8a0d9b25c187f69b0ace2f3 247 SMART SM00316 73 146 1.1E-8 T 31-10-2018 IPR022967 RNA-binding domain, S1 DFR86_06695 ea7db6c3b8a0d9b25c187f69b0ace2f3 247 SUPERFAMILY SSF54791 155 236 1.39E-17 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 DFR86_06695 ea7db6c3b8a0d9b25c187f69b0ace2f3 247 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 14 239 38.013 T 31-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 DFR86_06695 ea7db6c3b8a0d9b25c187f69b0ace2f3 247 Pfam PF15985 KH domain 157 203 4.9E-8 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 DFR86_08715 238fa91f4cea15df99a9b2e6207d5c44 344 PIRSF PIRSF015578 1 342 5.7E-68 T 31-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 DFR86_08715 238fa91f4cea15df99a9b2e6207d5c44 344 Gene3D G3DSA:3.30.360.10 180 285 2.3E-81 T 31-10-2018 DFR86_08715 238fa91f4cea15df99a9b2e6207d5c44 344 Gene3D G3DSA:3.40.50.720 2 325 2.3E-81 T 31-10-2018 DFR86_08715 238fa91f4cea15df99a9b2e6207d5c44 344 Pfam PF01658 Myo-inositol-1-phosphate synthase 181 285 6.0E-21 T 31-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 DFR86_08715 238fa91f4cea15df99a9b2e6207d5c44 344 SUPERFAMILY SSF51735 2 331 2.68E-63 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_08715 238fa91f4cea15df99a9b2e6207d5c44 344 SUPERFAMILY SSF55347 179 285 7.33E-25 T 31-10-2018 DFR86_07270 dfd7d4c1c828126037933b9e2be5111d 597 SUPERFAMILY SSF52540 243 593 1.03E-37 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07270 dfd7d4c1c828126037933b9e2be5111d 597 SMART SM00382 279 577 6.4E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_07270 dfd7d4c1c828126037933b9e2be5111d 597 Pfam PF12846 AAA-like domain 278 581 3.9E-12 T 31-10-2018 DFR86_00520 f69927f88d145ada2d192f3c2dad46c8 397 PIRSF PIRSF016578 12 394 2.1E-24 T 31-10-2018 DFR86_00520 f69927f88d145ada2d192f3c2dad46c8 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 226 2.8E-21 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 DFR86_00520 f69927f88d145ada2d192f3c2dad46c8 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 387 7.0E-37 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DFR86_00520 f69927f88d145ada2d192f3c2dad46c8 397 Gene3D G3DSA:2.40.110.10 129 243 1.7E-37 T 31-10-2018 DFR86_00520 f69927f88d145ada2d192f3c2dad46c8 397 SUPERFAMILY SSF47203 236 389 5.15E-45 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR86_00520 f69927f88d145ada2d192f3c2dad46c8 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 126 3.1E-23 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 DFR86_00520 f69927f88d145ada2d192f3c2dad46c8 397 SUPERFAMILY SSF56645 11 249 2.23E-68 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR86_00520 f69927f88d145ada2d192f3c2dad46c8 397 Gene3D G3DSA:1.10.540.10 4 128 1.2E-27 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 DFR86_00520 f69927f88d145ada2d192f3c2dad46c8 397 Gene3D G3DSA:1.20.140.10 244 393 3.6E-41 T 31-10-2018 DFR86_09995 fe3eb617d2fa6ba48ae729a16fafde68 589 Gene3D G3DSA:3.40.50.10490 442 589 5.6E-51 T 31-10-2018 DFR86_09995 fe3eb617d2fa6ba48ae729a16fafde68 589 Pfam PF13522 Glutamine amidotransferase domain 67 192 1.8E-20 T 31-10-2018 DFR86_09995 fe3eb617d2fa6ba48ae729a16fafde68 589 Pfam PF01380 SIS domain 290 413 2.8E-25 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR86_09995 fe3eb617d2fa6ba48ae729a16fafde68 589 Pfam PF01380 SIS domain 448 536 2.4E-18 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR86_09995 fe3eb617d2fa6ba48ae729a16fafde68 589 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 589 2.3E-197 T 31-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 DFR86_09995 fe3eb617d2fa6ba48ae729a16fafde68 589 SUPERFAMILY SSF53697 256 588 1.45E-90 T 31-10-2018 DFR86_09995 fe3eb617d2fa6ba48ae729a16fafde68 589 Gene3D G3DSA:3.40.50.10490 243 441 1.1E-54 T 31-10-2018 DFR86_09995 fe3eb617d2fa6ba48ae729a16fafde68 589 SUPERFAMILY SSF56235 2 230 1.03E-65 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_09995 fe3eb617d2fa6ba48ae729a16fafde68 589 Gene3D G3DSA:3.60.20.10 2 241 9.1E-69 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_04455 8fb5c486f7d71325688ebfcf37a13ea5 333 SUPERFAMILY SSF161098 103 314 2.94E-14 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_04455 8fb5c486f7d71325688ebfcf37a13ea5 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 332 4.2E-39 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_04455 8fb5c486f7d71325688ebfcf37a13ea5 333 Gene3D G3DSA:1.10.3720.10 96 325 1.6E-14 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_08345 c134e66b624dc8622ce388eb3fbe8ad2 87 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 1 79 15.991 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR86_08345 c134e66b624dc8622ce388eb3fbe8ad2 87 SUPERFAMILY SSF82697 2 77 5.93E-17 T 31-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR86_08345 c134e66b624dc8622ce388eb3fbe8ad2 87 Gene3D G3DSA:3.30.1280.10 1 87 2.1E-30 T 31-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR86_08345 c134e66b624dc8622ce388eb3fbe8ad2 87 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 2 78 5.7E-18 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR86_08345 c134e66b624dc8622ce388eb3fbe8ad2 87 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 77 9.0E-7 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR86_08345 c134e66b624dc8622ce388eb3fbe8ad2 87 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 1.3E-10 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR86_04305 c79f417f16559d81bafa775b3ff040be 407 Pfam PF01565 FAD binding domain 46 162 9.6E-25 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_04305 c79f417f16559d81bafa775b3ff040be 407 SUPERFAMILY SSF56176 18 205 1.26E-30 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_04305 c79f417f16559d81bafa775b3ff040be 407 SUPERFAMILY SSF55103 307 406 6.32E-6 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DFR86_04305 c79f417f16559d81bafa775b3ff040be 407 Gene3D G3DSA:3.30.465.40 20 225 1.7E-26 T 31-10-2018 DFR86_03510 beb67742be12264b1124f20a42c14445 275 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_03510 beb67742be12264b1124f20a42c14445 275 SUPERFAMILY SSF52540 2 219 1.57E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03510 beb67742be12264b1124f20a42c14445 275 Gene3D G3DSA:3.40.50.300 1 237 8.1E-55 T 31-10-2018 DFR86_03510 beb67742be12264b1124f20a42c14445 275 SMART SM00382 26 205 3.8E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_03510 beb67742be12264b1124f20a42c14445 275 Pfam PF00005 ABC transporter 23 160 1.6E-22 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_01085 3ac8bf026edf9791361a89b31729f528 324 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_01085 3ac8bf026edf9791361a89b31729f528 324 SMART SM00382 45 240 2.6E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_01085 3ac8bf026edf9791361a89b31729f528 324 SUPERFAMILY SSF52540 47 309 7.73E-67 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01085 3ac8bf026edf9791361a89b31729f528 324 Pfam PF00005 ABC transporter 36 183 1.2E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_01085 3ac8bf026edf9791361a89b31729f528 324 Gene3D G3DSA:3.40.50.300 24 324 7.4E-91 T 31-10-2018 DFR86_01085 3ac8bf026edf9791361a89b31729f528 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 296 2.7E-19 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_01085 3ac8bf026edf9791361a89b31729f528 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 315 2.4E-24 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_06590 aac93f28a061e72b2266aa1f3c2b613f 61 ProSitePatterns PS01077 Ribosomal protein L37e signature. 3 23 - T 31-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06590 aac93f28a061e72b2266aa1f3c2b613f 61 Gene3D G3DSA:2.20.25.30 1 55 1.9E-22 T 31-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06590 aac93f28a061e72b2266aa1f3c2b613f 61 Pfam PF01907 Ribosomal protein L37e 1 54 2.0E-24 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06590 aac93f28a061e72b2266aa1f3c2b613f 61 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 1 54 20.292 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06590 aac93f28a061e72b2266aa1f3c2b613f 61 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 8 40 8.0E-10 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06590 aac93f28a061e72b2266aa1f3c2b613f 61 SUPERFAMILY SSF57829 1 55 3.3E-21 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR86_09120 80d1ff11252444e5cd9c7d15600e5968 455 Gene3D G3DSA:3.30.300.30 374 454 3.2E-13 T 31-10-2018 DFR86_09120 80d1ff11252444e5cd9c7d15600e5968 455 SUPERFAMILY SSF56801 2 454 1.13E-85 T 31-10-2018 DFR86_09120 80d1ff11252444e5cd9c7d15600e5968 455 Pfam PF00501 AMP-binding enzyme 10 377 1.2E-60 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR86_09120 80d1ff11252444e5cd9c7d15600e5968 455 Pfam PF13193 AMP-binding enzyme C-terminal domain 387 454 9.1E-10 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR86_09120 80d1ff11252444e5cd9c7d15600e5968 455 Gene3D G3DSA:3.40.50.12780 1 373 7.7E-70 T 31-10-2018 DFR86_05240 620bbc16f3aebe9fb8f6c6cf30510074 305 Pfam PF01925 Sulfite exporter TauE/SafE 15 292 9.8E-54 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 DFR86_10160 967cf85045a7c42ae814972a33cd4933 325 PIRSF PIRSF015950 2 325 7.6E-108 T 31-10-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 DFR86_10160 967cf85045a7c42ae814972a33cd4933 325 SUPERFAMILY SSF55060 179 323 1.73E-42 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR86_10160 967cf85045a7c42ae814972a33cd4933 325 Gene3D G3DSA:3.30.70.890 186 325 5.4E-48 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR86_10160 967cf85045a7c42ae814972a33cd4933 325 SUPERFAMILY SSF54211 6 176 8.35E-39 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_10160 967cf85045a7c42ae814972a33cd4933 325 Pfam PF00288 GHMP kinases N terminal domain 94 150 1.1E-7 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR86_10160 967cf85045a7c42ae814972a33cd4933 325 Gene3D G3DSA:3.30.230.10 4 185 2.6E-63 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR86_10160 967cf85045a7c42ae814972a33cd4933 325 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 7 306 2.4E-89 T 31-10-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 DFR86_01040 572bfc57c98e9a2e4ba8d0c151a9689c 165 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 39 70 1.4E-9 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DFR86_01040 572bfc57c98e9a2e4ba8d0c151a9689c 165 Gene3D G3DSA:1.10.12.20 7 77 3.5E-27 T 31-10-2018 DFR86_01040 572bfc57c98e9a2e4ba8d0c151a9689c 165 SUPERFAMILY SSF50249 11 154 7.37E-28 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_08600 63990de49ae45a847f9c8dcb9575813d 333 Gene3D G3DSA:1.10.3730.40 184 332 1.2E-52 T 31-10-2018 DFR86_08600 63990de49ae45a847f9c8dcb9575813d 333 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 330 39.082 T 31-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR86_08600 63990de49ae45a847f9c8dcb9575813d 333 Gene3D G3DSA:3.40.50.720 1 183 2.0E-76 T 31-10-2018 DFR86_08600 63990de49ae45a847f9c8dcb9575813d 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 2.4E-124 T 31-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR86_08600 63990de49ae45a847f9c8dcb9575813d 333 SUPERFAMILY SSF48179 185 326 3.23E-52 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_08600 63990de49ae45a847f9c8dcb9575813d 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 326 6.3E-50 T 31-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR86_08600 63990de49ae45a847f9c8dcb9575813d 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 2.1E-75 T 31-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR86_08600 63990de49ae45a847f9c8dcb9575813d 333 SUPERFAMILY SSF51735 4 184 1.29E-72 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_06555 a31724b7ea38789c1da647ec03e08704 155 SUPERFAMILY SSF47413 69 125 1.31E-12 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 DFR86_06555 a31724b7ea38789c1da647ec03e08704 155 Pfam PF01381 Helix-turn-helix 72 123 2.9E-8 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR86_06555 a31724b7ea38789c1da647ec03e08704 155 Gene3D G3DSA:1.10.260.40 58 155 4.5E-20 T 31-10-2018 DFR86_06555 a31724b7ea38789c1da647ec03e08704 155 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 3 150 8.4E-25 T 31-10-2018 IPR004451 Conserved hypothetical protein CHP00270 DFR86_06555 a31724b7ea38789c1da647ec03e08704 155 SMART SM00530 71 126 6.1E-9 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR86_01370 d8e605d8b7d607ee8555ba72bcfe8abb 333 Pfam PF00107 Zinc-binding dehydrogenase 176 294 1.3E-22 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR86_01370 d8e605d8b7d607ee8555ba72bcfe8abb 333 SMART SM00829 10 330 4.6E-10 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR86_01370 d8e605d8b7d607ee8555ba72bcfe8abb 333 SUPERFAMILY SSF50129 1 170 7.0E-45 T 31-10-2018 IPR011032 GroES-like superfamily DFR86_01370 d8e605d8b7d607ee8555ba72bcfe8abb 333 Gene3D G3DSA:3.90.180.10 1 333 6.0E-86 T 31-10-2018 DFR86_01370 d8e605d8b7d607ee8555ba72bcfe8abb 333 SUPERFAMILY SSF51735 140 307 7.24E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_01370 d8e605d8b7d607ee8555ba72bcfe8abb 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 132 3.3E-25 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR86_00525 2b347d6c5fa8e8803f35c9511339aa98 133 SUPERFAMILY SSF54637 6 131 1.73E-23 T 31-10-2018 IPR029069 HotDog domain superfamily DFR86_00525 2b347d6c5fa8e8803f35c9511339aa98 133 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 16 115 5.3E-12 T 31-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 DFR86_00525 2b347d6c5fa8e8803f35c9511339aa98 133 Gene3D G3DSA:3.10.129.10 1 129 4.2E-25 T 31-10-2018 DFR86_00525 2b347d6c5fa8e8803f35c9511339aa98 133 Pfam PF03061 Thioesterase superfamily 46 118 4.1E-11 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR86_01335 8fa6215b871e3ad9cdec9558e26558e4 424 Pfam PF03972 MmgE/PrpD family 6 401 3.4E-97 T 31-10-2018 IPR005656 MmgE/PrpD GO:0016829 DFR86_01335 8fa6215b871e3ad9cdec9558e26558e4 424 Gene3D G3DSA:3.30.1330.120 256 382 5.5E-93 T 31-10-2018 DFR86_01335 8fa6215b871e3ad9cdec9558e26558e4 424 Gene3D G3DSA:1.10.4100.10 14 409 5.5E-93 T 31-10-2018 DFR86_01335 8fa6215b871e3ad9cdec9558e26558e4 424 SUPERFAMILY SSF103378 2 417 3.14E-98 T 31-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 DFR86_03550 e61db16b8e549d3eeb190ae59a38ec81 184 Pfam PF04173 TQO small subunit DoxD 20 184 1.5E-69 T 31-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 PRINTS PR00171 Sugar transporter signature 30 40 2.0E-16 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 PRINTS PR00171 Sugar transporter signature 111 130 2.0E-16 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 PRINTS PR00171 Sugar transporter signature 382 394 2.0E-16 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 PRINTS PR00171 Sugar transporter signature 359 380 2.0E-16 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 PRINTS PR00171 Sugar transporter signature 265 275 2.0E-16 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 ProSitePatterns PS00216 Sugar transport proteins signature 1. 315 331 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 Pfam PF00083 Sugar (and other) transporter 23 458 1.9E-88 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 ProSitePatterns PS00217 Sugar transport proteins signature 2. 116 141 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 Gene3D G3DSA:1.20.1250.20 11 462 4.4E-107 T 31-10-2018 DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 SUPERFAMILY SSF103473 10 454 2.09E-67 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_04870 9379b6e61bd0168c3a1b84212e12226d 462 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 17 454 1.1E-79 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_06755 df440d5acc1351d18966818f6c3b770d 337 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 221 240 - T 31-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 DFR86_06755 df440d5acc1351d18966818f6c3b770d 337 SMART SM01329 3 332 2.2E-164 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 DFR86_06755 df440d5acc1351d18966818f6c3b770d 337 Gene3D G3DSA:3.40.718.10 1 337 7.0E-139 T 31-10-2018 DFR86_06755 df440d5acc1351d18966818f6c3b770d 337 SUPERFAMILY SSF53659 2 335 1.92E-113 T 31-10-2018 DFR86_06755 df440d5acc1351d18966818f6c3b770d 337 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 330 1.8E-98 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 DFR86_06755 df440d5acc1351d18966818f6c3b770d 337 TIGRFAM TIGR02088 LEU3_arch: isopropylmalate/isohomocitrate dehydrogenases 4 333 5.4E-137 T 31-10-2018 IPR011828 Isopropylmalate/isohomocitrate dehydrogenase GO:0003862|GO:0009098|GO:0051287|GO:0055114 DFR86_05365 6f804ffaed6b0dc991f491903f26a518 164 Pfam PF01864 CDP-archaeol synthase 2 164 4.3E-33 T 31-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 DFR86_05365 6f804ffaed6b0dc991f491903f26a518 164 Hamap MF_01117 CDP-archaeol synthase [carS]. 12 164 24.077 T 31-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 DFR86_06050 9ee508d9d499226fe27a88f51e0a3a9b 65 SMART SM01389 6 65 5.5E-20 T 31-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 DFR86_06050 9ee508d9d499226fe27a88f51e0a3a9b 65 Pfam PF06093 Spt4/RpoE2 zinc finger 7 64 9.2E-13 T 31-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 DFR86_06050 9ee508d9d499226fe27a88f51e0a3a9b 65 Gene3D G3DSA:2.20.28.90 2 65 1.0E-21 T 31-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily DFR86_06050 9ee508d9d499226fe27a88f51e0a3a9b 65 SUPERFAMILY SSF63393 6 64 8.89E-18 T 31-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 DFR86_06050 9ee508d9d499226fe27a88f51e0a3a9b 65 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 19 62 3.0E-13 T 31-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 DFR86_06050 9ee508d9d499226fe27a88f51e0a3a9b 65 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 8 65 24.779 T 31-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 DFR86_01385 b550f0e610d02df5569dc81a009af1f9 195 Hamap MF_00786 Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) [cbiT]. 12 194 32.043 T 31-10-2018 IPR023475 Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) CbiT GO:0008168 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 DFR86_01385 b550f0e610d02df5569dc81a009af1f9 195 SUPERFAMILY SSF53335 18 169 3.55E-31 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_01385 b550f0e610d02df5569dc81a009af1f9 195 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 22 145 5.3E-36 T 31-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 DFR86_01385 b550f0e610d02df5569dc81a009af1f9 195 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 30 99 1.2E-11 T 31-10-2018 DFR86_01385 b550f0e610d02df5569dc81a009af1f9 195 Gene3D G3DSA:3.40.50.150 3 195 5.5E-58 T 31-10-2018 DFR86_08395 d92a062ca38a47bd0ea1f3cd60e4bdb2 335 Gene3D G3DSA:1.20.58.220 242 332 5.0E-12 T 31-10-2018 IPR038078 PhoU-like domain superfamily DFR86_08395 d92a062ca38a47bd0ea1f3cd60e4bdb2 335 Pfam PF01895 PhoU domain 143 233 1.4E-19 T 31-10-2018 IPR026022 PhoU domain DFR86_08395 d92a062ca38a47bd0ea1f3cd60e4bdb2 335 Pfam PF01895 PhoU domain 245 323 2.2E-14 T 31-10-2018 IPR026022 PhoU domain DFR86_08395 d92a062ca38a47bd0ea1f3cd60e4bdb2 335 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 12 54 1.4E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_08395 d92a062ca38a47bd0ea1f3cd60e4bdb2 335 Gene3D G3DSA:1.20.58.220 128 241 1.2E-20 T 31-10-2018 IPR038078 PhoU-like domain superfamily DFR86_08395 d92a062ca38a47bd0ea1f3cd60e4bdb2 335 SUPERFAMILY SSF109755 132 328 1.26E-37 T 31-10-2018 DFR86_08395 d92a062ca38a47bd0ea1f3cd60e4bdb2 335 SMART SM00966 11 57 3.4E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_08395 d92a062ca38a47bd0ea1f3cd60e4bdb2 335 SUPERFAMILY SSF89447 14 55 2.09E-5 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR86_01960 1971eeb3a69baf4d7d2d2aefc2ccc256 579 Pfam PF00384 Molybdopterin oxidoreductase 318 380 7.7E-7 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_01960 1971eeb3a69baf4d7d2d2aefc2ccc256 579 Gene3D G3DSA:3.30.2070.10 373 454 6.6E-68 T 31-10-2018 DFR86_01960 1971eeb3a69baf4d7d2d2aefc2ccc256 579 SUPERFAMILY SSF53706 4 437 1.44E-67 T 31-10-2018 DFR86_01960 1971eeb3a69baf4d7d2d2aefc2ccc256 579 Gene3D G3DSA:3.40.50.740 55 417 6.6E-68 T 31-10-2018 DFR86_01960 1971eeb3a69baf4d7d2d2aefc2ccc256 579 Gene3D G3DSA:3.40.228.10 111 467 6.6E-68 T 31-10-2018 DFR86_04910 2f2357fb6a7d22d8877b30c082490ff1 676 ProDom PD038969 NUCLEOTIDE-BINDING HELICASE ATP-BINDING HYDROLASE PLASMID HELICASE PH1064 MJECL01 ATP-DEPENDENT 504 670 6.0E-23 T 31-10-2018 DFR86_04910 2f2357fb6a7d22d8877b30c082490ff1 676 Gene3D G3DSA:3.40.50.300 9 176 8.6E-24 T 31-10-2018 DFR86_04910 2f2357fb6a7d22d8877b30c082490ff1 676 Gene3D G3DSA:3.40.50.300 207 399 1.3E-25 T 31-10-2018 DFR86_04910 2f2357fb6a7d22d8877b30c082490ff1 676 SUPERFAMILY SSF52540 28 394 4.22E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04910 2f2357fb6a7d22d8877b30c082490ff1 676 SMART SM00487 13 190 1.1E-18 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_04910 2f2357fb6a7d22d8877b30c082490ff1 676 Pfam PF04851 Type III restriction enzyme, res subunit 15 163 3.1E-24 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 DFR86_04910 2f2357fb6a7d22d8877b30c082490ff1 676 SMART SM00490 310 392 2.9E-16 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_04910 2f2357fb6a7d22d8877b30c082490ff1 676 Pfam PF00271 Helicase conserved C-terminal domain 285 390 6.7E-17 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_01145 4b2b5612a2e1910c71530dcdbf387b36 394 Gene3D G3DSA:3.30.70.360 187 302 1.0E-140 T 31-10-2018 DFR86_01145 4b2b5612a2e1910c71530dcdbf387b36 394 SUPERFAMILY SSF53187 6 392 5.14E-88 T 31-10-2018 DFR86_01145 4b2b5612a2e1910c71530dcdbf387b36 394 Pfam PF01546 Peptidase family M20/M25/M40 77 373 4.2E-32 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR86_01145 4b2b5612a2e1910c71530dcdbf387b36 394 SUPERFAMILY SSF55031 190 297 4.32E-29 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain DFR86_01145 4b2b5612a2e1910c71530dcdbf387b36 394 Pfam PF07687 Peptidase dimerisation domain 191 286 3.7E-15 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR86_01145 4b2b5612a2e1910c71530dcdbf387b36 394 PIRSF PIRSF005962 2 394 4.4E-126 T 31-10-2018 IPR017439 Amidohydrolase GO:0016787 DFR86_01145 4b2b5612a2e1910c71530dcdbf387b36 394 Gene3D G3DSA:3.40.630.10 18 376 1.0E-140 T 31-10-2018 DFR86_01145 4b2b5612a2e1910c71530dcdbf387b36 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 379 1.1E-130 T 31-10-2018 IPR017439 Amidohydrolase GO:0016787 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 406 417 - T 31-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 PIRSF PIRSF000854 6 781 5.7E-255 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 SUPERFAMILY SSF52009 344 453 4.45E-37 T 31-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 SUPERFAMILY SSF56059 9 374 6.83E-101 T 31-10-2018 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 11 777 0.0 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 679 697 - T 31-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 340 1.3E-115 T 31-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 Gene3D G3DSA:3.30.1490.20 7 188 4.9E-64 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 Gene3D G3DSA:3.50.30.10 349 456 7.0E-45 T 31-10-2018 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 Gene3D G3DSA:3.20.20.60 483 776 3.4E-93 T 31-10-2018 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 475 776 2.6E-80 T 31-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 Gene3D G3DSA:3.30.470.20 189 348 1.9E-49 T 31-10-2018 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 Pfam PF00391 PEP-utilising enzyme, mobile domain 376 447 4.6E-28 T 31-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DFR86_09565 6778714736a5729a529ba4b781c4ec72 786 SUPERFAMILY SSF51621 475 781 2.17E-92 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR86_06360 0a8195e2bd8b53cbdf5e3843230cb720 404 SUPERFAMILY SSF55021 329 395 1.34E-6 T 31-10-2018 DFR86_06360 0a8195e2bd8b53cbdf5e3843230cb720 404 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 24 400 2.2E-139 T 31-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 DFR86_06360 0a8195e2bd8b53cbdf5e3843230cb720 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 305 1.2E-83 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR86_06360 0a8195e2bd8b53cbdf5e3843230cb720 404 Gene3D G3DSA:3.40.50.1100 53 149 1.4E-115 T 31-10-2018 DFR86_06360 0a8195e2bd8b53cbdf5e3843230cb720 404 SUPERFAMILY SSF53686 7 316 9.95E-96 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR86_06360 0a8195e2bd8b53cbdf5e3843230cb720 404 Gene3D G3DSA:3.40.50.1100 12 310 1.4E-115 T 31-10-2018 DFR86_07065 2bc82ff6ac3505f495292e9d7459977f 233 Pfam PF13192 Thioredoxin domain 145 224 8.2E-15 T 31-10-2018 IPR012336 Thioredoxin-like fold DFR86_07065 2bc82ff6ac3505f495292e9d7459977f 233 Pfam PF13192 Thioredoxin domain 40 117 1.5E-10 T 31-10-2018 IPR012336 Thioredoxin-like fold DFR86_07065 2bc82ff6ac3505f495292e9d7459977f 233 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 12 228 3.4E-75 T 31-10-2018 IPR011903 Glutaredoxin-like domain DFR86_07065 2bc82ff6ac3505f495292e9d7459977f 233 SUPERFAMILY SSF52833 11 126 4.07E-13 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_07065 2bc82ff6ac3505f495292e9d7459977f 233 Gene3D G3DSA:3.40.30.10 129 227 4.9E-25 T 31-10-2018 DFR86_07065 2bc82ff6ac3505f495292e9d7459977f 233 Gene3D G3DSA:3.40.30.10 9 124 2.8E-27 T 31-10-2018 DFR86_07065 2bc82ff6ac3505f495292e9d7459977f 233 SUPERFAMILY SSF52833 132 224 7.84E-16 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_04075 4e9911eb4f66ccf680af11deedcd6aeb 173 Pfam PF04173 TQO small subunit DoxD 12 173 1.6E-62 T 31-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 DFR86_11555 84b14132cc83f9784fa83809f426f8d4 240 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 6 175 3.8E-43 T 31-10-2018 IPR010153 CRISPR-associated protein, Cas5a type DFR86_11555 84b14132cc83f9784fa83809f426f8d4 240 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 6 44 4.1E-7 T 31-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal DFR86_11555 84b14132cc83f9784fa83809f426f8d4 240 Gene3D G3DSA:3.30.70.3120 2 240 2.4E-37 T 31-10-2018 DFR86_09560 37a98cfb3c1e1841ce1fa06b94d8efd0 95 SUPERFAMILY SSF57903 48 91 4.14E-6 T 31-10-2018 IPR011011 Zinc finger, FYVE/PHD-type DFR86_01025 b2e67a2f25a53b76d602e4c674467827 141 Pfam PF06157 Protein of unknown function (DUF973) 49 136 1.4E-8 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR86_06145 171a562a62bc7874ee78ba039b098232 248 SUPERFAMILY SSF55979 1 108 4.71E-22 T 31-10-2018 DFR86_06145 171a562a62bc7874ee78ba039b098232 248 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 2 248 21.994 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_06145 171a562a62bc7874ee78ba039b098232 248 Gene3D G3DSA:3.70.10.10 1 243 3.6E-67 T 31-10-2018 DFR86_06145 171a562a62bc7874ee78ba039b098232 248 SUPERFAMILY SSF55979 128 248 1.07E-19 T 31-10-2018 DFR86_06145 171a562a62bc7874ee78ba039b098232 248 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 1 109 9.2E-9 T 31-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_08015 98f77a253df4eca089027ab4becc671b 205 Pfam PF01930 Domain of unknown function DUF83 58 199 1.0E-7 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 DFR86_08015 98f77a253df4eca089027ab4becc671b 205 SUPERFAMILY SSF52980 102 158 7.24E-5 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR86_08015 98f77a253df4eca089027ab4becc671b 205 Gene3D G3DSA:3.90.320.10 1 204 8.1E-70 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal DFR86_08015 98f77a253df4eca089027ab4becc671b 205 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 23 200 1.7E-27 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 DFR86_11560 56e8691972e75b579770a377c6e5ac8e 505 SMART SM00490 261 340 1.3E-7 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_11560 56e8691972e75b579770a377c6e5ac8e 505 Pfam PF00271 Helicase conserved C-terminal domain 242 339 2.2E-8 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_11560 56e8691972e75b579770a377c6e5ac8e 505 SMART SM00487 15 230 5.3E-7 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_11560 56e8691972e75b579770a377c6e5ac8e 505 SUPERFAMILY SSF52540 30 345 1.09E-31 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_11560 56e8691972e75b579770a377c6e5ac8e 505 Pfam PF00270 DEAD/DEAH box helicase 27 203 4.2E-11 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_11560 56e8691972e75b579770a377c6e5ac8e 505 Gene3D G3DSA:3.40.50.300 12 210 2.8E-15 T 31-10-2018 DFR86_11560 56e8691972e75b579770a377c6e5ac8e 505 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 36 376 1.3E-65 T 31-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core DFR86_11560 56e8691972e75b579770a377c6e5ac8e 505 Gene3D G3DSA:3.40.50.300 221 384 1.2E-15 T 31-10-2018 DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 3 485 2.4E-167 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 SUPERFAMILY SSF55874 12 225 6.81E-36 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 2 503 29.14 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 SUPERFAMILY SSF46946 228 301 2.62E-14 T 31-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 Gene3D G3DSA:3.30.230.10 306 527 8.0E-84 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 SUPERFAMILY SSF54211 306 466 6.75E-63 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 PIRSF PIRSF006553 1 526 1.9E-201 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 Gene3D G3DSA:3.30.565.10 1 227 1.5E-67 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 305 526 1.0E-80 T 31-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 SMART SM00387 25 148 2.9E-4 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 Gene3D G3DSA:1.10.8.50 228 305 3.5E-29 T 31-10-2018 DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 Pfam PF09239 Topoisomerase VI B subunit, transducer 307 465 2.4E-66 T 31-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 DFR86_09870 56368ebbf6c94936766ba20191ddfa4d 527 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 140 2.4E-10 T 31-10-2018 DFR86_03155 166bb1685648a2f160407843de9196b4 739 Pfam PF01565 FAD binding domain 52 111 4.7E-9 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_03155 166bb1685648a2f160407843de9196b4 739 Gene3D G3DSA:3.30.465.10 43 127 4.4E-8 T 31-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 DFR86_03155 166bb1685648a2f160407843de9196b4 739 SUPERFAMILY SSF56176 8 115 2.1E-10 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_03155 166bb1685648a2f160407843de9196b4 739 Gene3D G3DSA:1.10.1060.10 281 360 9.8E-6 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_03155 166bb1685648a2f160407843de9196b4 739 SUPERFAMILY SSF46548 272 352 5.75E-12 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_03155 166bb1685648a2f160407843de9196b4 739 Pfam PF13183 4Fe-4S dicluster domain 290 347 1.8E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_07745 f80b5057aa5e190bc88faf2ef3acbbe2 234 SUPERFAMILY SSF50447 1 88 2.01E-14 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR86_07745 f80b5057aa5e190bc88faf2ef3acbbe2 234 Pfam PF01411 tRNA synthetases class II (A) 13 92 2.6E-12 T 31-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 DFR86_07745 f80b5057aa5e190bc88faf2ef3acbbe2 234 Gene3D G3DSA:3.30.980.10 89 234 1.5E-33 T 31-10-2018 DFR86_07745 f80b5057aa5e190bc88faf2ef3acbbe2 234 Gene3D G3DSA:2.40.30.130 1 88 4.7E-24 T 31-10-2018 DFR86_07745 f80b5057aa5e190bc88faf2ef3acbbe2 234 SMART SM00863 187 230 6.7E-13 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 DFR86_07745 f80b5057aa5e190bc88faf2ef3acbbe2 234 SUPERFAMILY SSF55186 92 231 1.7E-35 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 DFR86_07745 f80b5057aa5e190bc88faf2ef3acbbe2 234 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 188 230 3.2E-11 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 DFR86_07540 e5bccdf6e619fc35bc29f3deafa3721c 194 PRINTS PR00410 Phenol hydroxylase reductase family signature 39 46 1.5E-5 T 31-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 DFR86_07540 e5bccdf6e619fc35bc29f3deafa3721c 194 PRINTS PR00410 Phenol hydroxylase reductase family signature 24 36 1.5E-5 T 31-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 DFR86_07540 e5bccdf6e619fc35bc29f3deafa3721c 194 PRINTS PR00410 Phenol hydroxylase reductase family signature 95 114 1.5E-5 T 31-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 DFR86_07540 e5bccdf6e619fc35bc29f3deafa3721c 194 SUPERFAMILY SSF52343 74 188 8.12E-15 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain DFR86_07540 e5bccdf6e619fc35bc29f3deafa3721c 194 Gene3D G3DSA:2.40.30.10 2 80 2.2E-9 T 31-10-2018 DFR86_07540 e5bccdf6e619fc35bc29f3deafa3721c 194 Gene3D G3DSA:3.40.50.80 86 191 5.6E-9 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain DFR86_07540 e5bccdf6e619fc35bc29f3deafa3721c 194 SUPERFAMILY SSF63380 14 82 1.08E-7 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel DFR86_09295 3519e67b8431ff4d425b8331901f2b02 358 Pfam PF00108 Thiolase, N-terminal domain 36 177 1.4E-10 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR86_09295 3519e67b8431ff4d425b8331901f2b02 358 PIRSF PIRSF000429 13 349 1.8E-27 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR86_09295 3519e67b8431ff4d425b8331901f2b02 358 SUPERFAMILY SSF53901 4 220 8.93E-24 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_09295 3519e67b8431ff4d425b8331901f2b02 358 Gene3D G3DSA:3.40.47.10 3 355 2.6E-60 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_09295 3519e67b8431ff4d425b8331901f2b02 358 SUPERFAMILY SSF53901 246 327 3.04E-11 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_02100 5815a26fe6c6538f866632c718f26fa5 185 Pfam PF10120 Thiamine-phosphate synthase 11 177 5.6E-53 T 31-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DFR86_02100 5815a26fe6c6538f866632c718f26fa5 185 SUPERFAMILY SSF53639 3 181 8.63E-55 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR86_02100 5815a26fe6c6538f866632c718f26fa5 185 Gene3D G3DSA:3.40.225.10 1 183 5.3E-57 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR86_03625 818818e9980b66ed6799f6ae593fbe5e 438 SUPERFAMILY SSF56059 47 430 3.98E-23 T 31-10-2018 DFR86_03625 818818e9980b66ed6799f6ae593fbe5e 438 PIRSF PIRSF005522 8 438 5.6E-104 T 31-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 DFR86_03625 818818e9980b66ed6799f6ae593fbe5e 438 Gene3D G3DSA:3.30.1490.270 324 376 7.2E-8 T 31-10-2018 DFR86_03625 818818e9980b66ed6799f6ae593fbe5e 438 Gene3D G3DSA:3.40.50.11290 196 285 9.6E-21 T 31-10-2018 DFR86_03625 818818e9980b66ed6799f6ae593fbe5e 438 Pfam PF14403 Circularly permuted ATP-grasp type 2 67 413 1.5E-78 T 31-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 DFR86_02355 d82716dc9df12f60a5e2d89a4fe4ee45 244 SUPERFAMILY SSF53335 22 242 2.5E-36 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_02355 d82716dc9df12f60a5e2d89a4fe4ee45 244 Gene3D G3DSA:3.40.50.150 25 224 7.1E-40 T 31-10-2018 DFR86_02355 d82716dc9df12f60a5e2d89a4fe4ee45 244 Pfam PF13649 Methyltransferase domain 45 135 5.1E-16 T 31-10-2018 DFR86_02355 d82716dc9df12f60a5e2d89a4fe4ee45 244 Gene3D G3DSA:2.20.25.110 144 202 7.1E-40 T 31-10-2018 DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 PIRSF PIRSF036983 1 374 4.8E-98 T 31-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 278 364 4.9E-6 T 31-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 Gene3D G3DSA:3.10.580.10 2 123 1.5E-18 T 31-10-2018 DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 SUPERFAMILY SSF54631 123 256 8.06E-29 T 31-10-2018 DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 SUPERFAMILY SSF69754 274 368 7.72E-11 T 31-10-2018 IPR036567 Ribosome hibernation promotion factor-like DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 Pfam PF00571 CBS domain 9 55 1.3E-5 T 31-10-2018 IPR000644 CBS domain DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 Pfam PF00571 CBS domain 127 180 2.5E-11 T 31-10-2018 IPR000644 CBS domain DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 Pfam PF00571 CBS domain 67 117 1.5E-6 T 31-10-2018 IPR000644 CBS domain DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 Pfam PF00571 CBS domain 203 256 8.9E-10 T 31-10-2018 IPR000644 CBS domain DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 SMART SM00116 10 57 1.3E-4 T 31-10-2018 IPR000644 CBS domain DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 SMART SM00116 210 257 1.6E-6 T 31-10-2018 IPR000644 CBS domain DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 SMART SM00116 134 181 4.4E-6 T 31-10-2018 IPR000644 CBS domain DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 SMART SM00116 69 117 1.7E-5 T 31-10-2018 IPR000644 CBS domain DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 Gene3D G3DSA:3.30.160.100 273 371 1.0E-5 T 31-10-2018 IPR036567 Ribosome hibernation promotion factor-like DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 Gene3D G3DSA:3.10.580.10 124 256 3.2E-29 T 31-10-2018 DFR86_02055 54d123ca57091ff20119aaf897a7aadc 374 SUPERFAMILY SSF54631 3 118 2.78E-19 T 31-10-2018 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 PRINTS PR01047 Threonyl-tRNA synthetase signature 223 251 2.1E-52 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 PRINTS PR01047 Threonyl-tRNA synthetase signature 430 442 2.1E-52 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 PRINTS PR01047 Threonyl-tRNA synthetase signature 360 388 2.1E-52 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 PRINTS PR01047 Threonyl-tRNA synthetase signature 256 279 2.1E-52 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 PRINTS PR01047 Threonyl-tRNA synthetase signature 403 416 2.1E-52 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 3 530 29.612 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 SUPERFAMILY SSF55681 136 422 6.89E-89 T 31-10-2018 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 SUPERFAMILY SSF55186 16 133 3.92E-8 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 103 527 1.9E-164 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 Gene3D G3DSA:3.40.50.800 428 540 1.4E-30 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 SUPERFAMILY SSF52954 427 528 1.81E-27 T 31-10-2018 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 Pfam PF03129 Anticodon binding domain 437 526 1.6E-18 T 31-10-2018 IPR004154 Anticodon-binding DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 216 424 7.1E-41 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_10115 6d59fcb399654ad7665426c55b7457d8 543 Gene3D G3DSA:3.30.930.10 115 427 2.6E-120 T 31-10-2018 DFR86_04410 1211e3456dcedbca9755868282a65298 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 232 9.6E-47 T 31-10-2018 DFR86_04410 1211e3456dcedbca9755868282a65298 249 Gene3D G3DSA:3.40.50.720 1 239 6.9E-66 T 31-10-2018 DFR86_04410 1211e3456dcedbca9755868282a65298 249 SUPERFAMILY SSF51735 6 235 7.39E-66 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_04410 1211e3456dcedbca9755868282a65298 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.4E-31 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04410 1211e3456dcedbca9755868282a65298 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 1.4E-31 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04410 1211e3456dcedbca9755868282a65298 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.4E-31 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04410 1211e3456dcedbca9755868282a65298 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.4E-31 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04410 1211e3456dcedbca9755868282a65298 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.4E-31 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04410 1211e3456dcedbca9755868282a65298 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-31 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04410 1211e3456dcedbca9755868282a65298 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 7.6E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04410 1211e3456dcedbca9755868282a65298 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 7.6E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_04410 1211e3456dcedbca9755868282a65298 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 7.6E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09915 20364aff50d159ffddaaa14d910c01a4 226 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 35.329 T 31-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 DFR86_09915 20364aff50d159ffddaaa14d910c01a4 226 Gene3D G3DSA:3.40.1160.10 1 226 1.5E-61 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR86_09915 20364aff50d159ffddaaa14d910c01a4 226 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 223 1.1E-80 T 31-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 DFR86_09915 20364aff50d159ffddaaa14d910c01a4 226 SUPERFAMILY SSF53633 1 223 9.56E-42 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR86_09915 20364aff50d159ffddaaa14d910c01a4 226 PIRSF PIRSF005650 1 226 4.9E-53 T 31-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 DFR86_09915 20364aff50d159ffddaaa14d910c01a4 226 Pfam PF00696 Amino acid kinase family 1 203 4.2E-27 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 98 409 1.0E-84 T 31-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 SUPERFAMILY SSF52374 98 418 8.31E-85 T 31-10-2018 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 4 570 1.5E-159 T 31-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 Gene3D G3DSA:2.40.240.10 421 511 2.2E-36 T 31-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 Gene3D G3DSA:2.40.240.100 414 570 2.2E-36 T 31-10-2018 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 SUPERFAMILY SSF50715 412 567 1.46E-19 T 31-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 102 114 2.7E-22 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 116 127 2.7E-22 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 131 144 2.7E-22 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 285 295 2.7E-22 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 PRINTS PR00987 Glutamyl-tRNA synthetase signature 301 309 2.7E-22 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 7 569 32.629 T 31-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 412 557 1.2E-21 T 31-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_05710 e8e76bcd6b7f45f028e1d50ef1ea77d9 571 Gene3D G3DSA:3.40.50.620 60 413 1.1E-109 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_02870 e622ce17bece2b592b0123e09ef90c57 299 SUPERFAMILY SSF82861 56 134 6.41E-9 T 31-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 DFR86_02870 e622ce17bece2b592b0123e09ef90c57 299 Pfam PF00924 Mechanosensitive ion channel 95 285 3.2E-21 T 31-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 DFR86_02870 e622ce17bece2b592b0123e09ef90c57 299 SUPERFAMILY SSF50182 136 204 8.83E-7 T 31-10-2018 IPR010920 LSM domain superfamily DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 PRINTS PR00114 Serine/threonine phosphatase family signature 159 186 6.3E-25 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 PRINTS PR00114 Serine/threonine phosphatase family signature 130 156 6.3E-25 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 PRINTS PR00114 Serine/threonine phosphatase family signature 64 91 6.3E-25 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 PRINTS PR00114 Serine/threonine phosphatase family signature 97 121 6.3E-25 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 PRINTS PR00114 Serine/threonine phosphatase family signature 238 254 6.3E-25 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 PRINTS PR00114 Serine/threonine phosphatase family signature 36 63 6.3E-25 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 SMART SM00156 6 266 7.2E-72 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 Gene3D G3DSA:3.60.21.10 6 265 6.0E-78 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 98 103 - T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 Pfam PF00149 Calcineurin-like phosphoesterase 37 228 2.1E-28 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR86_07490 247943aaca7cb0ee3037bf03b80ebf3d 267 SUPERFAMILY SSF56300 9 263 4.1E-72 T 31-10-2018 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Pfam PF00009 Elongation factor Tu GTP binding domain 19 259 5.9E-61 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 SMART SM00889 511 625 1.0E-21 T 31-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 SUPERFAMILY SSF54211 469 629 1.82E-51 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Gene3D G3DSA:3.30.70.870 394 471 2.3E-24 T 31-10-2018 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Pfam PF03764 Elongation factor G, domain IV 516 624 8.4E-30 T 31-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 SUPERFAMILY SSF50447 261 379 1.61E-31 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 SUPERFAMILY SSF54980 630 722 7.67E-23 T 31-10-2018 IPR035647 EF-G domain III/V-like DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Pfam PF03144 Elongation factor Tu domain 2 308 374 3.8E-13 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 SUPERFAMILY SSF52540 6 264 1.17E-70 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 31-10-2018 IPR031157 Tr-type G domain, conserved site DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Gene3D G3DSA:2.40.30.10 261 378 9.0E-24 T 31-10-2018 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 SUPERFAMILY SSF54980 393 469 4.32E-22 T 31-10-2018 IPR035647 EF-G domain III/V-like DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 PRINTS PR00315 GTP-binding elongation factor signature 22 35 2.5E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 PRINTS PR00315 GTP-binding elongation factor signature 106 117 2.5E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 PRINTS PR00315 GTP-binding elongation factor signature 142 151 2.5E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 PRINTS PR00315 GTP-binding elongation factor signature 90 100 2.5E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 PRINTS PR00315 GTP-binding elongation factor signature 66 74 2.5E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 SMART SM00838 627 714 5.4E-42 T 31-10-2018 IPR000640 Elongation factor EFG, domain V-like DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Hamap MF_00054_A Elongation factor G [fusA]. 1 731 42.217 T 31-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Gene3D G3DSA:3.30.70.240 472 724 3.6E-84 T 31-10-2018 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Gene3D G3DSA:3.30.230.10 478 727 3.6E-84 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Pfam PF00679 Elongation factor G C-terminus 628 711 4.6E-22 T 31-10-2018 IPR000640 Elongation factor EFG, domain V-like DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Gene3D G3DSA:3.40.50.300 5 222 8.2E-72 T 31-10-2018 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 5 724 9.2E-279 T 31-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 Pfam PF14492 Elongation Factor G, domain II 392 465 1.2E-23 T 31-10-2018 DFR86_06735 787ac71bfbb8bf7a2f8697f0ef7aa4d3 736 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 151 7.9E-21 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 DFR86_04460 176b8eacb2e9353bb0a8916d1539a32c 657 Gene3D G3DSA:3.40.190.10 29 306 1.5E-24 T 31-10-2018 DFR86_04460 176b8eacb2e9353bb0a8916d1539a32c 657 Gene3D G3DSA:3.10.105.10 322 563 3.3E-29 T 31-10-2018 DFR86_04460 176b8eacb2e9353bb0a8916d1539a32c 657 SUPERFAMILY SSF53850 37 583 8.07E-57 T 31-10-2018 DFR86_04460 176b8eacb2e9353bb0a8916d1539a32c 657 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 489 5.7E-42 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 Gene3D G3DSA:1.10.8.60 346 442 1.1E-30 T 31-10-2018 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 SUPERFAMILY SSF50692 3 87 1.22E-22 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 ProSitePatterns PS00674 AAA-protein family signature. 315 333 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 SUPERFAMILY SSF52540 172 440 9.85E-74 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 5 744 0.0 T 31-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 104 167 9.6E-16 T 31-10-2018 IPR004201 CDC48, domain 2 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 7 88 5.2E-25 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 Gene3D G3DSA:3.40.50.300 448 735 2.2E-102 T 31-10-2018 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 Gene3D G3DSA:2.40.40.20 1 89 4.9E-24 T 31-10-2018 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 ProSitePatterns PS00674 AAA-protein family signature. 591 609 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 SMART SM00382 486 623 1.3E-24 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 SMART SM00382 211 347 4.6E-25 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 Gene3D G3DSA:3.40.50.300 171 344 2.0E-72 T 31-10-2018 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 SUPERFAMILY SSF52540 448 741 5.89E-75 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 SUPERFAMILY SSF54585 90 180 7.52E-20 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 SMART SM01073 6 89 6.0E-31 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 Gene3D G3DSA:1.10.8.60 622 722 2.2E-102 T 31-10-2018 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 SMART SM01072 104 167 6.9E-17 T 31-10-2018 IPR004201 CDC48, domain 2 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 490 620 2.5E-48 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_06035 cdaa2487bfca680ed42fee71e5c410e3 747 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 215 344 5.5E-49 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_08990 0bee211e06714ba91275d147cf753080 243 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 1 242 26.3 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_08990 0bee211e06714ba91275d147cf753080 243 SUPERFAMILY SSF55979 2 117 5.97E-23 T 31-10-2018 DFR86_08990 0bee211e06714ba91275d147cf753080 243 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 7 94 4.0E-11 T 31-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_08990 0bee211e06714ba91275d147cf753080 243 SUPERFAMILY SSF55979 123 242 2.86E-27 T 31-10-2018 DFR86_08990 0bee211e06714ba91275d147cf753080 243 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 33 56 - T 31-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_08990 0bee211e06714ba91275d147cf753080 243 Gene3D G3DSA:3.70.10.10 2 242 2.3E-60 T 31-10-2018 DFR86_08990 0bee211e06714ba91275d147cf753080 243 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 128 240 1.7E-10 T 31-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_08990 0bee211e06714ba91275d147cf753080 243 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 33 51 1.3E-10 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_08990 0bee211e06714ba91275d147cf753080 243 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 55 79 1.3E-10 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_08990 0bee211e06714ba91275d147cf753080 243 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 228 243 1.3E-10 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_08990 0bee211e06714ba91275d147cf753080 243 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 190 204 1.3E-10 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_08990 0bee211e06714ba91275d147cf753080 243 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 9 28 1.3E-10 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 Gene3D G3DSA:1.10.132.60 624 784 5.1E-43 T 31-10-2018 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 SUPERFAMILY SSF53098 6 374 3.45E-73 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily DFR86_05830 405b740ca298645878408bf609d8a5fe 784 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 508 520 1.6E-11 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 425 438 1.6E-11 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 560 568 1.6E-11 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 Gene3D G3DSA:1.10.287.690 472 524 7.6E-67 T 31-10-2018 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 Gene3D G3DSA:3.90.1600.10 408 612 7.6E-67 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 277 761 3.5E-84 T 31-10-2018 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 ProSitePatterns PS00116 DNA polymerase family B signature. 562 570 - T 31-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 Pfam PF00136 DNA polymerase family B 363 761 3.3E-77 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 SMART SM00486 171 574 1.1E-106 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 Pfam PF03104 DNA polymerase family B, exonuclease domain 27 292 7.3E-44 T 31-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_05830 405b740ca298645878408bf609d8a5fe 784 SUPERFAMILY SSF56672 379 778 1.67E-117 T 31-10-2018 DFR86_11530 9d73b20959e6dd93498a6f9614b43879 304 Gene3D G3DSA:1.20.120.920 82 303 1.2E-42 T 31-10-2018 DFR86_11530 9d73b20959e6dd93498a6f9614b43879 304 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 3 298 1.1E-63 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR86_11530 9d73b20959e6dd93498a6f9614b43879 304 Gene3D G3DSA:3.100.10.20 2 80 9.3E-19 T 31-10-2018 DFR86_11530 9d73b20959e6dd93498a6f9614b43879 304 Pfam PF01867 CRISPR associated protein Cas1 4 126 1.4E-20 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR86_11530 9d73b20959e6dd93498a6f9614b43879 304 Pfam PF01867 CRISPR associated protein Cas1 137 235 3.9E-29 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR86_11530 9d73b20959e6dd93498a6f9614b43879 304 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 289 22.12 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR86_03175 0f0eea939a238ead01a54a5ab8cb6a75 178 Gene3D G3DSA:1.10.3210.10 2 166 7.8E-33 T 31-10-2018 DFR86_03175 0f0eea939a238ead01a54a5ab8cb6a75 178 SMART SM00471 27 138 2.0E-10 T 31-10-2018 IPR003607 HD/PDEase domain DFR86_03175 0f0eea939a238ead01a54a5ab8cb6a75 178 SUPERFAMILY SSF109604 11 153 6.77E-26 T 31-10-2018 DFR86_03175 0f0eea939a238ead01a54a5ab8cb6a75 178 Pfam PF13023 HD domain 11 152 7.0E-17 T 31-10-2018 IPR006674 HD domain DFR86_11220 cf257e8e2742cb7810bd5a1f33623b8b 272 Pfam PF13240 zinc-ribbon domain 4 25 1.4E-7 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR86_04715 896d20bf1f6e91c6f718ec44d29a84bb 589 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 48 482 7.1E-72 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04715 896d20bf1f6e91c6f718ec44d29a84bb 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 253 274 1.5E-12 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04715 896d20bf1f6e91c6f718ec44d29a84bb 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 299 314 1.5E-12 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04715 896d20bf1f6e91c6f718ec44d29a84bb 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 87 110 1.5E-12 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04715 896d20bf1f6e91c6f718ec44d29a84bb 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 37 62 1.5E-12 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04715 896d20bf1f6e91c6f718ec44d29a84bb 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 114 138 1.5E-12 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04715 896d20bf1f6e91c6f718ec44d29a84bb 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 1.5E-12 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04715 896d20bf1f6e91c6f718ec44d29a84bb 589 SUPERFAMILY SSF81442 35 515 5.36E-78 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04715 896d20bf1f6e91c6f718ec44d29a84bb 589 Gene3D G3DSA:1.20.210.10 22 525 8.8E-81 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_08480 6dca81539689baf6f18e0f2a414ca53d 132 Pfam PF01883 Iron-sulfur cluster assembly protein 10 82 2.7E-18 T 31-10-2018 IPR002744 MIP18 family-like DFR86_08480 6dca81539689baf6f18e0f2a414ca53d 132 Gene3D G3DSA:3.30.300.130 2 105 1.1E-28 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily DFR86_08480 6dca81539689baf6f18e0f2a414ca53d 132 SUPERFAMILY SSF117916 9 103 3.2E-25 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily DFR86_03780 d105770a549a4ad1519eb16db48a4053 232 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 11 199 3.2E-46 T 31-10-2018 DFR86_03780 d105770a549a4ad1519eb16db48a4053 232 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 6 199 1.2E-47 T 31-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 DFR86_03780 d105770a549a4ad1519eb16db48a4053 232 Gene3D G3DSA:3.40.50.150 1 232 1.6E-62 T 31-10-2018 DFR86_03780 d105770a549a4ad1519eb16db48a4053 232 SUPERFAMILY SSF53335 1 184 8.52E-41 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_02095 308d7eea53194b4661167a9857cb1a72 149 Gene3D G3DSA:1.10.10.10 2 108 1.7E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_02095 308d7eea53194b4661167a9857cb1a72 149 Pfam PF03551 Transcriptional regulator PadR-like family 17 86 3.0E-19 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal DFR86_02095 308d7eea53194b4661167a9857cb1a72 149 SUPERFAMILY SSF46785 7 95 1.64E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_09130 c10f43e9d6f0315a745321a68b5a7ed5 201 SMART SM00382 21 196 1.6E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_09130 c10f43e9d6f0315a745321a68b5a7ed5 201 Pfam PF00005 ABC transporter 14 150 4.2E-21 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_09130 c10f43e9d6f0315a745321a68b5a7ed5 201 Gene3D G3DSA:3.40.50.300 5 200 1.0E-36 T 31-10-2018 DFR86_09130 c10f43e9d6f0315a745321a68b5a7ed5 201 SUPERFAMILY SSF52540 14 198 9.3E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08820 d85a57815bd9f6c218f990aaeea501b3 436 Pfam PF01964 Radical SAM ThiC family 3 419 1.6E-173 T 31-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 DFR86_08820 d85a57815bd9f6c218f990aaeea501b3 436 Gene3D G3DSA:3.20.20.540 44 363 8.8E-129 T 31-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 DFR86_08820 d85a57815bd9f6c218f990aaeea501b3 436 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 3 419 4.0E-163 T 31-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 DFR86_07955 142e8d2009251c72c242af308912e6b0 360 SUPERFAMILY SSF103473 4 355 1.57E-31 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_07955 142e8d2009251c72c242af308912e6b0 360 Gene3D G3DSA:1.20.1250.20 1 180 2.3E-16 T 31-10-2018 DFR86_07955 142e8d2009251c72c242af308912e6b0 360 Gene3D G3DSA:1.20.1250.20 181 359 2.4E-10 T 31-10-2018 DFR86_07955 142e8d2009251c72c242af308912e6b0 360 Pfam PF07690 Major Facilitator Superfamily 7 325 7.8E-17 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_11250 6e34caa1816e4a1310905774854c4f87 97 Gene3D G3DSA:3.30.70.100 6 94 3.7E-17 T 31-10-2018 DFR86_11250 6e34caa1816e4a1310905774854c4f87 97 SUPERFAMILY SSF54909 1 95 9.73E-23 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR86_11250 6e34caa1816e4a1310905774854c4f87 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 4.4E-16 T 31-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain DFR86_02910 05837386bdf4f247d0d2c7192811e272 282 Gene3D G3DSA:3.40.1190.20 5 277 5.5E-48 T 31-10-2018 IPR029056 Ribokinase-like DFR86_02910 05837386bdf4f247d0d2c7192811e272 282 PRINTS PR00990 Ribokinase signature 34 53 1.8E-7 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR86_02910 05837386bdf4f247d0d2c7192811e272 282 PRINTS PR00990 Ribokinase signature 7 28 1.8E-7 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR86_02910 05837386bdf4f247d0d2c7192811e272 282 PRINTS PR00990 Ribokinase signature 189 200 1.8E-7 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR86_02910 05837386bdf4f247d0d2c7192811e272 282 SUPERFAMILY SSF53613 6 268 2.81E-45 T 31-10-2018 IPR029056 Ribokinase-like DFR86_02910 05837386bdf4f247d0d2c7192811e272 282 Pfam PF00294 pfkB family carbohydrate kinase 181 259 2.3E-16 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB DFR86_02910 05837386bdf4f247d0d2c7192811e272 282 Pfam PF00294 pfkB family carbohydrate kinase 7 140 5.4E-12 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 PIRSF PIRSF000445 9 409 4.4E-95 T 31-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 10 392 21.002 T 31-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 SUPERFAMILY SSF51735 171 266 9.09E-17 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 40 393 2.7E-67 T 31-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 SUPERFAMILY SSF69075 293 395 3.66E-20 T 31-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 257 2.1E-17 T 31-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 296 393 2.6E-16 T 31-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 17 155 9.2E-36 T 31-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 98 121 - T 31-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 Gene3D G3DSA:3.30.460.30 16 157 2.7E-36 T 31-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 SUPERFAMILY SSF69742 11 157 2.62E-35 T 31-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR86_07130 777358e2a47612c9a405ced3b54a8627 416 Gene3D G3DSA:3.40.50.720 158 296 3.7E-25 T 31-10-2018 DFR86_01650 dce51902e0a54ef66f078bf16864c137 370 Pfam PF00005 ABC transporter 12 139 4.7E-16 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_01650 dce51902e0a54ef66f078bf16864c137 370 Pfam PF00005 ABC transporter 256 325 8.1E-7 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_01650 dce51902e0a54ef66f078bf16864c137 370 ProSitePatterns PS00211 ABC transporters family signature. 298 312 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_01650 dce51902e0a54ef66f078bf16864c137 370 Gene3D G3DSA:3.40.50.300 222 370 2.7E-28 T 31-10-2018 DFR86_01650 dce51902e0a54ef66f078bf16864c137 370 Gene3D G3DSA:3.40.50.300 8 202 1.3E-31 T 31-10-2018 DFR86_01650 dce51902e0a54ef66f078bf16864c137 370 SUPERFAMILY SSF52540 12 185 7.31E-30 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01650 dce51902e0a54ef66f078bf16864c137 370 SMART SM00382 17 183 4.6E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_01650 dce51902e0a54ef66f078bf16864c137 370 SMART SM00382 231 370 2.4E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_01650 dce51902e0a54ef66f078bf16864c137 370 SUPERFAMILY SSF52540 226 370 5.51E-31 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07060 4b35afb1919aeca80f1a6d42637ee855 223 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 16 196 2.9E-58 T 31-10-2018 IPR027623 AmmeMemoRadiSam system protein A DFR86_07060 4b35afb1919aeca80f1a6d42637ee855 223 Gene3D G3DSA:3.30.1490.150 117 192 3.0E-89 T 31-10-2018 DFR86_07060 4b35afb1919aeca80f1a6d42637ee855 223 Gene3D G3DSA:3.30.700.20 9 204 3.0E-89 T 31-10-2018 IPR027485 AMMECR1, N-terminal DFR86_07060 4b35afb1919aeca80f1a6d42637ee855 223 SUPERFAMILY SSF143447 4 210 2.35E-65 T 31-10-2018 IPR036071 AMMECR1 domain superfamily DFR86_07060 4b35afb1919aeca80f1a6d42637ee855 223 Hamap MF_00645 Protein . 10 194 35.851 T 31-10-2018 IPR023472 Uncharacterised protein family MJ0810 DFR86_07060 4b35afb1919aeca80f1a6d42637ee855 223 Pfam PF01871 AMMECR1 21 196 7.8E-49 T 31-10-2018 IPR002733 AMMECR1 domain DFR86_07060 4b35afb1919aeca80f1a6d42637ee855 223 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 7 208 9.0E-62 T 31-10-2018 IPR023473 AMMECR1 DFR86_09710 241e55f1d72e7e7d382728162672bc5d 417 Gene3D G3DSA:3.30.420.220 1 103 7.8E-33 T 31-10-2018 DFR86_09710 241e55f1d72e7e7d382728162672bc5d 417 Pfam PF01798 snoRNA binding domain, fibrillarin 143 368 5.3E-75 T 31-10-2018 IPR002687 Nop domain DFR86_09710 241e55f1d72e7e7d382728162672bc5d 417 Gene3D G3DSA:1.10.246.90 249 373 9.6E-50 T 31-10-2018 DFR86_09710 241e55f1d72e7e7d382728162672bc5d 417 SMART SM00931 135 187 1.2E-26 T 31-10-2018 IPR012976 NOSIC DFR86_09710 241e55f1d72e7e7d382728162672bc5d 417 SUPERFAMILY SSF89124 130 370 2.62E-80 T 31-10-2018 IPR036070 Nop domain superfamily DFR86_09710 241e55f1d72e7e7d382728162672bc5d 417 Gene3D G3DSA:1.10.287.660 136 248 9.4E-41 T 31-10-2018 IPR029012 Helix hairpin bin domain superfamily DFR86_09710 241e55f1d72e7e7d382728162672bc5d 417 Gene3D G3DSA:1.10.150.460 166 217 9.4E-41 T 31-10-2018 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 Gene3D G3DSA:1.10.472.10 197 287 1.6E-23 T 31-10-2018 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 PRINTS PR00685 Transcription initiation factor IIB signature 234 250 5.6E-37 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 PRINTS PR00685 Transcription initiation factor IIB signature 200 218 5.6E-37 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 PRINTS PR00685 Transcription initiation factor IIB signature 37 50 5.6E-37 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 PRINTS PR00685 Transcription initiation factor IIB signature 266 280 5.6E-37 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 PRINTS PR00685 Transcription initiation factor IIB signature 15 35 5.6E-37 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 PRINTS PR00685 Transcription initiation factor IIB signature 147 166 5.6E-37 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 PRINTS PR00685 Transcription initiation factor IIB signature 173 188 5.6E-37 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 286 35.213 T 31-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 SUPERFAMILY SSF47954 196 286 1.56E-25 T 31-10-2018 IPR036915 Cyclin-like superfamily DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 Gene3D G3DSA:1.10.472.170 4 186 1.8E-55 T 31-10-2018 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 SMART SM00385 199 280 8.6E-7 T 31-10-2018 IPR013763 Cyclin-like DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 SMART SM00385 105 186 6.8E-9 T 31-10-2018 IPR013763 Cyclin-like DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 Pfam PF00382 Transcription factor TFIIB repeat 203 271 3.7E-16 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 Pfam PF00382 Transcription factor TFIIB repeat 108 170 3.9E-16 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 SUPERFAMILY SSF57783 5 46 5.87E-10 T 31-10-2018 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 233 248 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 SUPERFAMILY SSF47954 99 186 6.81E-24 T 31-10-2018 IPR036915 Cyclin-like superfamily DFR86_01855 e1739d14c356b8e035047ff23bd343e7 290 Pfam PF08271 TFIIB zinc-binding 6 42 1.9E-9 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 Pfam PF00515 Tetratricopeptide repeat 190 223 2.7E-9 T 31-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 Gene3D G3DSA:1.25.40.10 64 123 6.2E-6 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 Pfam PF13432 Tetratricopeptide repeat 129 189 6.7E-4 T 31-10-2018 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 Pfam PF13432 Tetratricopeptide repeat 10 58 0.0051 T 31-10-2018 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 Gene3D G3DSA:1.25.40.10 187 261 3.1E-20 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 SUPERFAMILY SSF48452 122 254 8.35E-31 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 Gene3D G3DSA:1.25.40.10 124 186 2.5E-8 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 SUPERFAMILY SSF48452 28 153 2.15E-12 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 SMART SM00028 224 257 42.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 SMART SM00028 32 65 130.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 SMART SM00028 156 189 0.49 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 SMART SM00028 122 155 12.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 SMART SM00028 190 223 3.9E-8 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 SMART SM00028 87 120 200.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_01595 de76fa3df588d8a5962c211ea6acc334 261 Gene3D G3DSA:1.25.40.10 3 63 7.4E-7 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_02590 2e68959e735bbd1e4cb599165db56361 212 Gene3D G3DSA:3.40.1280.10 1 211 7.5E-68 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DFR86_02590 2e68959e735bbd1e4cb599165db56361 212 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 211 30.892 T 31-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 DFR86_02590 2e68959e735bbd1e4cb599165db56361 212 Pfam PF03587 EMG1/NEP1 methyltransferase 4 206 2.8E-41 T 31-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 DFR86_02590 2e68959e735bbd1e4cb599165db56361 212 SUPERFAMILY SSF75217 1 207 3.53E-52 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases DFR86_04135 c22cf7c170c2f88bb8bceacc2a812de9 118 Gene3D G3DSA:3.10.580.10 6 118 2.1E-11 T 31-10-2018 DFR86_04135 c22cf7c170c2f88bb8bceacc2a812de9 118 SUPERFAMILY SSF54631 8 114 1.46E-11 T 31-10-2018 DFR86_04135 c22cf7c170c2f88bb8bceacc2a812de9 118 Pfam PF00571 CBS domain 12 47 2.7E-4 T 31-10-2018 IPR000644 CBS domain DFR86_04135 c22cf7c170c2f88bb8bceacc2a812de9 118 SMART SM00116 66 113 0.4 T 31-10-2018 IPR000644 CBS domain DFR86_04135 c22cf7c170c2f88bb8bceacc2a812de9 118 SMART SM00116 8 54 12.0 T 31-10-2018 IPR000644 CBS domain DFR86_09215 b09e79f58aece4ac5ab48dbcb34716cf 88 SMART SM01380 6 82 4.6E-9 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09215 b09e79f58aece4ac5ab48dbcb34716cf 88 SUPERFAMILY SSF54575 4 84 3.79E-17 T 31-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09215 b09e79f58aece4ac5ab48dbcb34716cf 88 Gene3D G3DSA:3.10.440.10 1 86 9.1E-13 T 31-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09215 b09e79f58aece4ac5ab48dbcb34716cf 88 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 7 48 0.006 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09215 b09e79f58aece4ac5ab48dbcb34716cf 88 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 2 84 15.384 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09215 b09e79f58aece4ac5ab48dbcb34716cf 88 Pfam PF01198 Ribosomal protein L31e 8 71 3.6E-6 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_01750 e63c61bf33de936657eafddc76526749 260 Gene3D G3DSA:3.40.50.300 1 234 1.1E-70 T 31-10-2018 DFR86_01750 e63c61bf33de936657eafddc76526749 260 TIGRFAM TIGR03881 KaiC_arch_4: KaiC domain protein, PAE1156 family 2 230 5.8E-117 T 31-10-2018 IPR022443 KaiC-related DFR86_01750 e63c61bf33de936657eafddc76526749 260 PRINTS PR01874 DNA repair protein radA signature 55 72 7.0E-7 T 31-10-2018 DFR86_01750 e63c61bf33de936657eafddc76526749 260 PRINTS PR01874 DNA repair protein radA signature 13 41 7.0E-7 T 31-10-2018 DFR86_01750 e63c61bf33de936657eafddc76526749 260 SUPERFAMILY SSF52540 1 227 2.76E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01750 e63c61bf33de936657eafddc76526749 260 Pfam PF06745 KaiC 5 229 3.7E-58 T 31-10-2018 IPR014774 KaiC-like domain DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 72 107 - T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 Pfam PF01096 Transcription factor S-II (TFIIS) 71 108 1.3E-21 T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 Gene3D G3DSA:2.20.25.10 56 111 3.9E-23 T 31-10-2018 DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 34 4.3E-11 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 Gene3D G3DSA:2.20.25.10 1 40 1.3E-5 T 31-10-2018 DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 SUPERFAMILY SSF57783 1 41 5.95E-6 T 31-10-2018 DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 SUPERFAMILY SSF57783 62 111 1.87E-21 T 31-10-2018 DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 SMART SM00440 70 109 1.2E-24 T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 PIRSF PIRSF005586 1 111 4.5E-37 T 31-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 27 - T 31-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 SMART SM00661 2 53 1.3E-16 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR86_08925 ebc6eeb55f6665ba38097817fcf0ce31 111 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 111 8.3E-36 T 31-10-2018 IPR006288 Transcription factor S GO:0006355 DFR86_06370 6a57dae04490c326483edd2e2f0b26e5 324 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 11 321 69.657 T 31-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 DFR86_06370 6a57dae04490c326483edd2e2f0b26e5 324 Pfam PF08423 Rad51 73 322 7.9E-89 T 31-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 DFR86_06370 6a57dae04490c326483edd2e2f0b26e5 324 Pfam PF14520 Helix-hairpin-helix domain 13 67 1.9E-9 T 31-10-2018 DFR86_06370 6a57dae04490c326483edd2e2f0b26e5 324 Gene3D G3DSA:3.40.50.300 85 324 1.4E-79 T 31-10-2018 DFR86_06370 6a57dae04490c326483edd2e2f0b26e5 324 Gene3D G3DSA:1.10.150.20 21 84 2.6E-22 T 31-10-2018 DFR86_06370 6a57dae04490c326483edd2e2f0b26e5 324 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 14 321 3.8E-142 T 31-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 DFR86_06370 6a57dae04490c326483edd2e2f0b26e5 324 SMART SM00382 106 291 9.9E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_06370 6a57dae04490c326483edd2e2f0b26e5 324 SUPERFAMILY SSF52540 86 321 1.3E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06370 6a57dae04490c326483edd2e2f0b26e5 324 PIRSF PIRSF005856 3 324 8.7E-127 T 31-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 DFR86_06370 6a57dae04490c326483edd2e2f0b26e5 324 SUPERFAMILY SSF47794 5 70 3.61E-11 T 31-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 DFR86_05180 048e850a12bbd71f19aaaa7857676018 319 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 182 311 1.2E-20 T 31-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 DFR86_05180 048e850a12bbd71f19aaaa7857676018 319 Gene3D G3DSA:3.40.50.10490 15 168 3.7E-27 T 31-10-2018 DFR86_05180 048e850a12bbd71f19aaaa7857676018 319 TIGRFAM TIGR02128 G6PI_arch: bifunctional phosphoglucose/phosphomannose isomerase 26 314 1.3E-74 T 31-10-2018 IPR011857 Bifunctional phosphoglucose/phosphomannose isomerase GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 DFR86_05180 048e850a12bbd71f19aaaa7857676018 319 Gene3D G3DSA:3.40.50.10490 182 314 7.4E-17 T 31-10-2018 DFR86_05180 048e850a12bbd71f19aaaa7857676018 319 SUPERFAMILY SSF53697 73 307 2.62E-31 T 31-10-2018 DFR86_02675 ce9dc4702a5e5b81d852e565dc1d9339 224 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 85 6.4E-7 T 31-10-2018 DFR86_02675 ce9dc4702a5e5b81d852e565dc1d9339 224 Pfam PF08282 haloacid dehalogenase-like hydrolase 125 209 2.0E-17 T 31-10-2018 DFR86_02675 ce9dc4702a5e5b81d852e565dc1d9339 224 Gene3D G3DSA:3.40.50.1000 3 207 2.4E-37 T 31-10-2018 IPR023214 HAD superfamily DFR86_02675 ce9dc4702a5e5b81d852e565dc1d9339 224 Gene3D G3DSA:3.90.1070.10 80 139 2.4E-37 T 31-10-2018 DFR86_02675 ce9dc4702a5e5b81d852e565dc1d9339 224 SUPERFAMILY SSF56784 2 210 1.95E-33 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_02675 ce9dc4702a5e5b81d852e565dc1d9339 224 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 3 208 2.2E-47 T 31-10-2018 DFR86_02675 ce9dc4702a5e5b81d852e565dc1d9339 224 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 4 210 2.7E-41 T 31-10-2018 DFR86_09300 e88390eff7d77f1e1ccc1eae4948aa59 131 Gene3D G3DSA:1.10.12.20 12 48 4.2E-5 T 31-10-2018 DFR86_09300 e88390eff7d77f1e1ccc1eae4948aa59 131 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 49 110 3.3E-16 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DFR86_09300 e88390eff7d77f1e1ccc1eae4948aa59 131 SUPERFAMILY SSF50249 9 115 2.06E-24 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_03795 c202ec6613fcd1dd5321243c3292bc1a 624 SUPERFAMILY SSF52922 510 617 4.45E-16 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR86_03795 c202ec6613fcd1dd5321243c3292bc1a 624 Gene3D G3DSA:3.40.920.10 1 217 1.6E-11 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR86_03795 c202ec6613fcd1dd5321243c3292bc1a 624 Gene3D G3DSA:3.40.50.920 502 613 6.2E-25 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR86_03795 c202ec6613fcd1dd5321243c3292bc1a 624 SUPERFAMILY SSF53323 4 214 9.42E-16 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR86_03795 c202ec6613fcd1dd5321243c3292bc1a 624 SUPERFAMILY SSF52518 225 492 7.0E-62 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_03795 c202ec6613fcd1dd5321243c3292bc1a 624 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 206 3.2E-32 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DFR86_03795 c202ec6613fcd1dd5321243c3292bc1a 624 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 3 608 1.3E-180 T 31-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 DFR86_03795 c202ec6613fcd1dd5321243c3292bc1a 624 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 239 485 1.4E-61 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DFR86_03795 c202ec6613fcd1dd5321243c3292bc1a 624 Gene3D G3DSA:3.40.50.970 218 424 2.1E-70 T 31-10-2018 DFR86_03795 c202ec6613fcd1dd5321243c3292bc1a 624 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 512 580 1.8E-7 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II DFR86_04925 4b418e7ffb232c5d1a416a80313bfd93 231 Gene3D G3DSA:3.40.50.10310 6 229 4.9E-46 T 31-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 DFR86_04925 4b418e7ffb232c5d1a416a80313bfd93 231 Pfam PF02633 Creatinine amidohydrolase 12 223 2.4E-43 T 31-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 DFR86_04925 4b418e7ffb232c5d1a416a80313bfd93 231 SUPERFAMILY SSF102215 1 227 4.71E-50 T 31-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 DFR86_03435 9d92bade63fa9314ea4b57da4a2c479f 535 SUPERFAMILY SSF49464 154 232 1.61E-7 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily DFR86_03435 9d92bade63fa9314ea4b57da4a2c479f 535 Gene3D G3DSA:2.60.40.1120 146 232 3.2E-8 T 31-10-2018 DFR86_03435 9d92bade63fa9314ea4b57da4a2c479f 535 SUPERFAMILY SSF58100 322 504 1.75E-6 T 31-10-2018 DFR86_03435 9d92bade63fa9314ea4b57da4a2c479f 535 Pfam PF13620 Carboxypeptidase regulatory-like domain 153 230 4.5E-8 T 31-10-2018 DFR86_03435 9d92bade63fa9314ea4b57da4a2c479f 535 Gene3D G3DSA:1.20.5.340 429 509 4.1E-11 T 31-10-2018 DFR86_08620 7212d4447609e2ae4b210156e33d514c 336 SUPERFAMILY SSF51366 58 304 1.65E-61 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR86_08620 7212d4447609e2ae4b210156e33d514c 336 ProSitePatterns PS01235 PdxS/SNZ family signature. 245 263 - T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR86_08620 7212d4447609e2ae4b210156e33d514c 336 Gene3D G3DSA:3.20.20.70 40 334 2.6E-125 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_08620 7212d4447609e2ae4b210156e33d514c 336 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 44 336 49.374 T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR86_08620 7212d4447609e2ae4b210156e33d514c 336 PIRSF PIRSF029271 36 336 1.9E-145 T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR86_08620 7212d4447609e2ae4b210156e33d514c 336 Pfam PF01680 SOR/SNZ family 47 252 2.1E-99 T 31-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR86_00575 3935f0cd9256e5dd13d0c9e457322fa1 429 Pfam PF14535 AMP-binding enzyme C-terminal domain 345 426 9.2E-12 T 31-10-2018 IPR028154 AMP-dependent ligase, C-terminal DFR86_00575 3935f0cd9256e5dd13d0c9e457322fa1 429 Gene3D G3DSA:3.30.300.30 337 428 6.3E-15 T 31-10-2018 DFR86_00575 3935f0cd9256e5dd13d0c9e457322fa1 429 Gene3D G3DSA:3.40.50.12780 6 336 1.6E-106 T 31-10-2018 DFR86_00575 3935f0cd9256e5dd13d0c9e457322fa1 429 SUPERFAMILY SSF56801 46 391 1.23E-49 T 31-10-2018 DFR86_00575 3935f0cd9256e5dd13d0c9e457322fa1 429 Pfam PF00501 AMP-binding enzyme 86 297 1.0E-15 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 ProSitePatterns PS00480 Citrate synthase signature. 254 266 - T 31-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 374 2.1E-147 T 31-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 Pfam PF00285 Citrate synthase, C-terminal domain 6 357 4.1E-129 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 PIRSF PIRSF001369 1 375 1.6E-145 T 31-10-2018 IPR024176 Citrate synthase, bacterial-type DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 Gene3D G3DSA:1.10.580.10 18 346 1.0E-136 T 31-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 PRINTS PR00143 Citrate synthase signature 194 222 3.1E-46 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 PRINTS PR00143 Citrate synthase signature 123 136 3.1E-46 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 PRINTS PR00143 Citrate synthase signature 307 323 3.1E-46 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 PRINTS PR00143 Citrate synthase signature 172 187 3.1E-46 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 PRINTS PR00143 Citrate synthase signature 327 341 3.1E-46 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 PRINTS PR00143 Citrate synthase signature 247 267 3.1E-46 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 Gene3D G3DSA:1.10.230.10 220 321 1.0E-136 T 31-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain DFR86_01790 5ac3b6ed834e5bbcb56a819296f97d53 375 SUPERFAMILY SSF48256 4 374 1.57E-132 T 31-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 DFR86_02995 3d54ba12ce0189cf75efa72e993d183d 140 Gene3D G3DSA:3.30.530.20 1 140 9.4E-27 T 31-10-2018 IPR023393 START-like domain superfamily DFR86_02995 3d54ba12ce0189cf75efa72e993d183d 140 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 5 137 5.7E-40 T 31-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G DFR86_02995 3d54ba12ce0189cf75efa72e993d183d 140 SUPERFAMILY SSF55961 1 139 1.17E-25 T 31-10-2018 DFR86_06690 59c860833967e3c91519e1287228502a 232 Gene3D G3DSA:3.30.1250.10 6 85 1.6E-26 T 31-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily DFR86_06690 59c860833967e3c91519e1287228502a 232 Gene3D G3DSA:1.10.10.900 86 160 1.3E-28 T 31-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily DFR86_06690 59c860833967e3c91519e1287228502a 232 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 5 228 3.7E-69 T 31-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 DFR86_06690 59c860833967e3c91519e1287228502a 232 Pfam PF09377 SBDS protein C-terminal domain 99 214 2.0E-21 T 31-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 DFR86_06690 59c860833967e3c91519e1287228502a 232 SUPERFAMILY SSF89895 3 84 1.05E-22 T 31-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily DFR86_06690 59c860833967e3c91519e1287228502a 232 SUPERFAMILY SSF109728 86 159 8.11E-24 T 31-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily DFR86_06690 59c860833967e3c91519e1287228502a 232 Gene3D G3DSA:3.30.70.240 162 231 1.5E-23 T 31-10-2018 DFR86_06690 59c860833967e3c91519e1287228502a 232 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 7 92 4.9E-24 T 31-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal DFR86_06690 59c860833967e3c91519e1287228502a 232 SUPERFAMILY SSF54980 155 227 3.17E-19 T 31-10-2018 IPR035647 EF-G domain III/V-like DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 SUPERFAMILY SSF81271 322 395 8.72E-18 T 31-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 Gene3D G3DSA:3.10.20.30 320 397 3.5E-32 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 SUPERFAMILY SSF52540 2 317 2.02E-68 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 2.2E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 2.2E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 93 111 2.2E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 76 91 2.2E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 Gene3D G3DSA:1.10.8.470 133 219 4.6E-24 T 31-10-2018 DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 Pfam PF08438 GTPase of unknown function C-terminal 224 328 1.0E-38 T 31-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 Pfam PF01926 50S ribosome-binding GTPase 4 130 9.5E-20 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_06660 6d72b0aa429776fb59a86e7be32d9b16 400 Pfam PF02824 TGS domain 339 394 2.6E-11 T 31-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 DFR86_08650 1760d95140a4e04d23f4213f3c2847a4 465 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 136 354 2.7E-64 T 31-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08650 1760d95140a4e04d23f4213f3c2847a4 465 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 13 79 1.6E-10 T 31-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08650 1760d95140a4e04d23f4213f3c2847a4 465 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 7 463 59.01 T 31-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08650 1760d95140a4e04d23f4213f3c2847a4 465 Gene3D G3DSA:3.40.50.12240 1 463 4.7E-174 T 31-10-2018 DFR86_08650 1760d95140a4e04d23f4213f3c2847a4 465 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 31-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08650 1760d95140a4e04d23f4213f3c2847a4 465 PIRSF PIRSF039114 1 465 4.3E-235 T 31-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08650 1760d95140a4e04d23f4213f3c2847a4 465 SUPERFAMILY SSF52540 83 358 4.3E-82 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 Pfam PF02637 GatB domain 490 628 2.3E-20 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 Pfam PF02934 GatB/GatE catalytic domain 12 450 2.0E-69 T 31-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 SUPERFAMILY SSF55931 2 458 5.95E-100 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 Gene3D G3DSA:1.10.10.410 570 629 2.3E-9 T 31-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 SUPERFAMILY SSF89095 497 629 3.4E-15 T 31-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 288 411 2.0E-44 T 31-10-2018 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 178 192 - T 31-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 Gene3D G3DSA:1.10.150.380 458 552 2.1E-13 T 31-10-2018 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 SMART SM00845 491 628 3.4E-22 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 SUPERFAMILY SSF55261 286 409 1.5E-44 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 Pfam PF02938 GAD domain 301 392 2.0E-13 T 31-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 3 630 3.5E-216 T 31-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 632 288.959 T 31-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 DFR86_09695 5fb3c603da6483da15b32835766aacf2 632 Gene3D G3DSA:3.30.1360.30 281 409 3.9E-45 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 DFR86_08695 5d683ad2e201dcca8496a370476a395f 161 SUPERFAMILY SSF53335 7 155 8.21E-33 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_08695 5d683ad2e201dcca8496a370476a395f 161 Pfam PF13847 Methyltransferase domain 30 141 2.2E-10 T 31-10-2018 IPR025714 Methyltransferase domain DFR86_08695 5d683ad2e201dcca8496a370476a395f 161 Gene3D G3DSA:3.40.50.150 1 161 2.1E-52 T 31-10-2018 DFR86_07410 5207024e6dc664bc8402d71f97839eb9 423 Gene3D G3DSA:3.30.70.360 178 334 2.5E-129 T 31-10-2018 DFR86_07410 5207024e6dc664bc8402d71f97839eb9 423 SUPERFAMILY SSF53187 2 422 1.31E-46 T 31-10-2018 DFR86_07410 5207024e6dc664bc8402d71f97839eb9 423 Pfam PF07687 Peptidase dimerisation domain 176 322 6.2E-19 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR86_07410 5207024e6dc664bc8402d71f97839eb9 423 SUPERFAMILY SSF55031 191 328 3.14E-5 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain DFR86_07410 5207024e6dc664bc8402d71f97839eb9 423 Gene3D G3DSA:3.40.630.10 10 409 2.5E-129 T 31-10-2018 DFR86_07410 5207024e6dc664bc8402d71f97839eb9 423 Pfam PF01546 Peptidase family M20/M25/M40 65 420 2.1E-32 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 PIRSF PIRSF002158 1 238 3.2E-67 T 31-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 SUPERFAMILY SSF50249 2 84 1.3E-16 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 80 8.0E-15 T 31-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 SMART SM01382 87 220 2.9E-61 T 31-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 Gene3D G3DSA:4.10.950.10 159 238 1.8E-37 T 31-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 235 38.336 T 31-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 Gene3D G3DSA:2.30.30.30 81 158 5.2E-25 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 SMART SM01383 11 81 5.1E-21 T 31-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 Gene3D G3DSA:2.40.50.140 1 77 1.4E-20 T 31-10-2018 DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 SUPERFAMILY SSF50104 90 234 1.75E-50 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR86_06785 9ac7cfa3099bb732fe305c13c1389959 238 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 89 215 9.7E-43 T 31-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 DFR86_02270 04cfd581eb8a8bf47b84c1ee7da9b7bc 132 Gene3D G3DSA:3.40.250.10 22 129 1.3E-21 T 31-10-2018 IPR036873 Rhodanese-like domain superfamily DFR86_02270 04cfd581eb8a8bf47b84c1ee7da9b7bc 132 Pfam PF00581 Rhodanese-like domain 21 108 7.0E-13 T 31-10-2018 IPR001763 Rhodanese-like domain DFR86_02270 04cfd581eb8a8bf47b84c1ee7da9b7bc 132 SUPERFAMILY SSF52821 11 119 1.07E-26 T 31-10-2018 IPR036873 Rhodanese-like domain superfamily DFR86_02270 04cfd581eb8a8bf47b84c1ee7da9b7bc 132 SMART SM00450 18 113 7.3E-18 T 31-10-2018 IPR001763 Rhodanese-like domain DFR86_09910 f536b0c80d9c1e33ea48edf4169d19db 59 Hamap MF_01387 Chromatin protein Cren7 [creN7]. 1 58 19.73 T 31-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 DFR86_09910 f536b0c80d9c1e33ea48edf4169d19db 59 Gene3D G3DSA:2.30.30.610 1 59 5.2E-33 T 31-10-2018 IPR038647 Cren7 superfamily DFR86_09910 f536b0c80d9c1e33ea48edf4169d19db 59 Pfam PF11520 Chromatin protein Cren7 1 57 2.8E-32 T 31-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 DFR86_04770 086be12846436ac608dd15419fd717e2 421 Pfam PF07690 Major Facilitator Superfamily 20 384 9.5E-39 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_04770 086be12846436ac608dd15419fd717e2 421 Gene3D G3DSA:1.20.1250.20 228 421 9.8E-25 T 31-10-2018 DFR86_04770 086be12846436ac608dd15419fd717e2 421 SUPERFAMILY SSF103473 9 421 1.57E-73 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_04770 086be12846436ac608dd15419fd717e2 421 Gene3D G3DSA:1.20.1250.20 6 214 1.6E-40 T 31-10-2018 DFR86_11240 dde6ba4b11c447f189a8144d6d329be3 104 SUPERFAMILY SSF54862 17 102 6.8E-20 T 31-10-2018 DFR86_11240 dde6ba4b11c447f189a8144d6d329be3 104 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_11240 dde6ba4b11c447f189a8144d6d329be3 104 Pfam PF13187 4Fe-4S dicluster domain 46 99 6.3E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_11240 dde6ba4b11c447f189a8144d6d329be3 104 PIRSF PIRSF000068 1 104 8.8E-40 T 31-10-2018 IPR009157 Ferredoxin zinc-binding GO:0008270|GO:0009055|GO:0051536 DFR86_11240 dde6ba4b11c447f189a8144d6d329be3 104 Gene3D G3DSA:3.30.70.20 2 104 1.4E-42 T 31-10-2018 DFR86_02830 f1f7fcffdac9b5f910251fb6f8096e48 308 SUPERFAMILY SSF56281 13 264 2.8E-18 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_02830 f1f7fcffdac9b5f910251fb6f8096e48 308 Gene3D G3DSA:3.60.15.10 9 274 6.0E-14 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_02830 f1f7fcffdac9b5f910251fb6f8096e48 308 Hamap MF_01406 UPF0282 protein . 1 287 39.457 T 31-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase DFR86_02830 f1f7fcffdac9b5f910251fb6f8096e48 308 PIRSF PIRSF004944 1 307 1.1E-118 T 31-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase DFR86_02830 f1f7fcffdac9b5f910251fb6f8096e48 308 Pfam PF13483 Beta-lactamase superfamily domain 17 108 7.9E-6 T 31-10-2018 DFR86_02830 f1f7fcffdac9b5f910251fb6f8096e48 308 SMART SM00849 14 238 3.9E-4 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.3E-26 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 272 290 1.3E-26 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 149 173 1.3E-26 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 1.3E-26 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.3E-26 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 1.3E-26 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 SUPERFAMILY SSF51905 1 303 6.02E-45 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 Hamap MF_01685 Ferredoxin--NADP reductase. 3 327 40.483 T 31-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 Gene3D G3DSA:3.50.50.60 5 305 7.5E-98 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 Gene3D G3DSA:3.50.50.60 125 243 7.5E-98 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 297 2.6E-31 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 2.0E-22 T 31-10-2018 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 2.0E-22 T 31-10-2018 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.0E-22 T 31-10-2018 DFR86_02615 db1fb7c7b961b3ca95788c55a0887bf3 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 2.0E-22 T 31-10-2018 DFR86_03060 8ec1407d4e8a63c87b08f1be5c6eb82c 500 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 1 488 1.3E-157 T 31-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein DFR86_03060 8ec1407d4e8a63c87b08f1be5c6eb82c 500 SUPERFAMILY SSF51717 188 367 5.49E-13 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 DFR86_03060 8ec1407d4e8a63c87b08f1be5c6eb82c 500 Gene3D G3DSA:3.20.20.20 162 363 8.7E-7 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 DFR86_06445 4307e5c2566847409a1a8cdcb2a26560 246 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 16 237 1.0E-81 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 DFR86_06445 4307e5c2566847409a1a8cdcb2a26560 246 Gene3D G3DSA:3.20.20.390 1 245 1.6E-81 T 31-10-2018 IPR038597 GGGP/HepGP synthase superfamily DFR86_06445 4307e5c2566847409a1a8cdcb2a26560 246 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 17 223 5.5E-85 T 31-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 DFR86_06445 4307e5c2566847409a1a8cdcb2a26560 246 SUPERFAMILY SSF51395 11 237 9.15E-41 T 31-10-2018 DFR86_06445 4307e5c2566847409a1a8cdcb2a26560 246 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 11 243 32.916 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 DFR86_06445 4307e5c2566847409a1a8cdcb2a26560 246 Pfam PF01884 PcrB family 9 237 6.1E-52 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 DFR86_05290 0106ef0c173f0abb5c1b7a944a5b1312 409 Gene3D G3DSA:3.50.50.60 115 276 4.4E-113 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05290 0106ef0c173f0abb5c1b7a944a5b1312 409 SUPERFAMILY SSF51905 3 336 5.62E-26 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05290 0106ef0c173f0abb5c1b7a944a5b1312 409 SUPERFAMILY SSF51905 120 267 9.5E-9 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05290 0106ef0c173f0abb5c1b7a944a5b1312 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 152 5.1E-12 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_05290 0106ef0c173f0abb5c1b7a944a5b1312 409 Gene3D G3DSA:3.50.50.60 4 333 4.4E-113 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05290 0106ef0c173f0abb5c1b7a944a5b1312 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 203 323 3.1E-7 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_10655 20370259cb1911dec45b84babee4426c 643 Gene3D G3DSA:3.30.70.20 566 640 1.6E-10 T 31-10-2018 DFR86_10655 20370259cb1911dec45b84babee4426c 643 Pfam PF13237 4Fe-4S dicluster domain 573 624 1.3E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_10655 20370259cb1911dec45b84babee4426c 643 SUPERFAMILY SSF54862 547 631 8.79E-14 T 31-10-2018 DFR86_03665 48c24552d08944aad80ff03e428cad93 227 SMART SM00382 24 189 4.7E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_03665 48c24552d08944aad80ff03e428cad93 227 Gene3D G3DSA:3.40.50.300 1 224 1.2E-46 T 31-10-2018 DFR86_03665 48c24552d08944aad80ff03e428cad93 227 SUPERFAMILY SSF52540 6 202 4.42E-47 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03665 48c24552d08944aad80ff03e428cad93 227 Pfam PF00005 ABC transporter 16 141 1.3E-17 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_06460 93036b31f2ef2a18ebbcb88cebcc60c5 233 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 48 225 1.2E-39 T 31-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 DFR86_06460 93036b31f2ef2a18ebbcb88cebcc60c5 233 Gene3D G3DSA:3.40.50.1360 4 225 5.4E-49 T 31-10-2018 DFR86_06460 93036b31f2ef2a18ebbcb88cebcc60c5 233 SUPERFAMILY SSF75445 134 211 2.49E-18 T 31-10-2018 DFR86_06460 93036b31f2ef2a18ebbcb88cebcc60c5 233 Gene3D G3DSA:3.30.70.260 129 208 5.4E-49 T 31-10-2018 DFR86_06460 93036b31f2ef2a18ebbcb88cebcc60c5 233 SUPERFAMILY SSF100950 1 151 4.69E-22 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR86_06460 93036b31f2ef2a18ebbcb88cebcc60c5 233 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 225 5.9E-42 T 31-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 DFR86_05010 9a056bbfd7c6c5aa3688a41885383bd5 521 Gene3D G3DSA:3.40.50.970 2 178 3.9E-41 T 31-10-2018 DFR86_05010 9a056bbfd7c6c5aa3688a41885383bd5 521 SUPERFAMILY SSF52518 16 181 3.39E-28 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_05010 9a056bbfd7c6c5aa3688a41885383bd5 521 SUPERFAMILY SSF52467 158 342 3.04E-15 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_05010 9a056bbfd7c6c5aa3688a41885383bd5 521 Gene3D G3DSA:3.40.50.970 344 521 1.4E-25 T 31-10-2018 DFR86_05010 9a056bbfd7c6c5aa3688a41885383bd5 521 SUPERFAMILY SSF52518 379 520 1.87E-23 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_05010 9a056bbfd7c6c5aa3688a41885383bd5 521 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 518 7.7E-17 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR86_05010 9a056bbfd7c6c5aa3688a41885383bd5 521 Gene3D G3DSA:3.40.50.1220 187 329 9.2E-11 T 31-10-2018 DFR86_05010 9a056bbfd7c6c5aa3688a41885383bd5 521 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 174 8.8E-38 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR86_08505 a17ebf7316573ffdfa6dcd7fce17e521 251 Gene3D G3DSA:3.20.20.70 1 251 1.8E-107 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_08505 a17ebf7316573ffdfa6dcd7fce17e521 251 SUPERFAMILY SSF51366 2 250 2.2E-80 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR86_08505 a17ebf7316573ffdfa6dcd7fce17e521 251 Pfam PF00977 Histidine biosynthesis protein 5 233 3.8E-85 T 31-10-2018 IPR006062 Histidine biosynthesis GO:0000105 DFR86_08505 a17ebf7316573ffdfa6dcd7fce17e521 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 250 2.7E-109 T 31-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 DFR86_08505 a17ebf7316573ffdfa6dcd7fce17e521 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 250 46.564 T 31-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 DFR86_05945 4d78f897776e7de9b450a4055dee722b 202 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 17 200 2.3E-55 T 31-10-2018 IPR004507 Flavin prenyltransferase UbiX-like DFR86_05945 4d78f897776e7de9b450a4055dee722b 202 SUPERFAMILY SSF52507 16 201 1.23E-49 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 DFR86_05945 4d78f897776e7de9b450a4055dee722b 202 Pfam PF02441 Flavoprotein 16 181 9.6E-27 T 31-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 DFR86_05945 4d78f897776e7de9b450a4055dee722b 202 Gene3D G3DSA:3.40.50.1950 12 202 1.5E-64 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 DFR86_05945 4d78f897776e7de9b450a4055dee722b 202 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 16 202 32.593 T 31-10-2018 IPR004507 Flavin prenyltransferase UbiX-like DFR86_04890 2e67795182d285fe9b6d61cd0ec41880 388 Pfam PF07690 Major Facilitator Superfamily 245 364 1.1E-11 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_04890 2e67795182d285fe9b6d61cd0ec41880 388 Pfam PF00083 Sugar (and other) transporter 36 185 1.8E-19 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR86_04890 2e67795182d285fe9b6d61cd0ec41880 388 Gene3D G3DSA:1.20.1250.20 5 191 8.6E-30 T 31-10-2018 DFR86_04890 2e67795182d285fe9b6d61cd0ec41880 388 SUPERFAMILY SSF103473 5 381 7.72E-51 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_04890 2e67795182d285fe9b6d61cd0ec41880 388 Gene3D G3DSA:1.20.1250.20 192 384 1.2E-18 T 31-10-2018 DFR86_08900 5a4074d897d72726c449ef275ff1d230 176 SUPERFAMILY SSF54686 4 167 4.84E-53 T 31-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_08900 5a4074d897d72726c449ef275ff1d230 176 Pfam PF00252 Ribosomal protein L16p/L10e 15 164 8.9E-31 T 31-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 DFR86_08900 5a4074d897d72726c449ef275ff1d230 176 Gene3D G3DSA:3.90.1170.10 1 176 9.8E-63 T 31-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_08900 5a4074d897d72726c449ef275ff1d230 176 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 35.736 T 31-10-2018 IPR022981 Ribosomal protein L10e, archaea DFR86_08900 5a4074d897d72726c449ef275ff1d230 176 PIRSF PIRSF005590 1 176 8.9E-66 T 31-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05810 1a2728131b1726402715fa4598081789 134 SUPERFAMILY SSF111038 1 134 1.18E-41 T 31-10-2018 IPR035917 YjbQ-like superfamily DFR86_05810 1a2728131b1726402715fa4598081789 134 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 7 134 6.6E-40 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 DFR86_05810 1a2728131b1726402715fa4598081789 134 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 96 114 - T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 DFR86_05810 1a2728131b1726402715fa4598081789 134 PIRSF PIRSF004681 1 134 8.9E-42 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 DFR86_05810 1a2728131b1726402715fa4598081789 134 Pfam PF01894 Uncharacterised protein family UPF0047 20 131 2.6E-37 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 DFR86_05810 1a2728131b1726402715fa4598081789 134 Gene3D G3DSA:2.60.120.460 1 134 1.0E-52 T 31-10-2018 IPR035917 YjbQ-like superfamily DFR86_03420 fd9dafff468abb14b72783e2076244f3 299 SMART SM00028 72 105 130.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_03420 fd9dafff468abb14b72783e2076244f3 299 SMART SM00028 263 296 110.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_03420 fd9dafff468abb14b72783e2076244f3 299 SMART SM00028 35 68 1.8 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_03420 fd9dafff468abb14b72783e2076244f3 299 SUPERFAMILY SSF48452 29 124 3.17E-10 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_03420 fd9dafff468abb14b72783e2076244f3 299 Gene3D G3DSA:1.25.40.10 185 298 3.5E-8 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_03420 fd9dafff468abb14b72783e2076244f3 299 Gene3D G3DSA:1.25.40.10 1 137 1.5E-9 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 Gene3D G3DSA:3.40.1110.10 503 607 7.2E-65 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 SUPERFAMILY SSF81665 248 764 1.02E-16 T 31-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 Pfam PF00403 Heavy-metal-associated domain 33 91 1.1E-15 T 31-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 268 761 1.1E-85 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 Gene3D G3DSA:3.40.50.1000 473 706 7.2E-65 T 31-10-2018 IPR023214 HAD superfamily DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 Gene3D G3DSA:3.30.70.100 104 155 3.7E-5 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 Gene3D G3DSA:2.70.150.20 287 397 9.7E-31 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 SUPERFAMILY SSF55008 32 93 6.54E-17 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 493 507 2.7E-20 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 671 690 2.7E-20 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 694 706 2.7E-20 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 632 2.7E-20 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 342 356 2.7E-20 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 Pfam PF00702 haloacid dehalogenase-like hydrolase 489 685 7.3E-37 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 Pfam PF00122 E1-E2 ATPase 293 473 2.1E-54 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 495 501 - T 31-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 Gene3D G3DSA:3.30.70.100 28 92 8.2E-19 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 ProSitePatterns PS01047 Heavy-metal-associated domain. 35 64 - T 31-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 SUPERFAMILY SSF81653 296 391 1.31E-24 T 31-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 235 772 6.8E-153 T 31-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 SUPERFAMILY SSF55008 95 163 3.14E-5 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 SUPERFAMILY SSF56784 491 771 1.52E-37 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 217 772 2.7E-154 T 31-10-2018 DFR86_11015 4ff74ceb24bf41eb9d463439d50b78b9 775 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 264 751 5.4E-110 T 31-10-2018 DFR86_10820 11a5aeddaca9d0bb6cd169dc1749789a 409 Gene3D G3DSA:1.20.1250.20 6 406 2.8E-52 T 31-10-2018 DFR86_10820 11a5aeddaca9d0bb6cd169dc1749789a 409 SUPERFAMILY SSF103473 3 389 1.57E-51 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_10820 11a5aeddaca9d0bb6cd169dc1749789a 409 Pfam PF07690 Major Facilitator Superfamily 12 354 1.2E-31 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_09365 77218c14380a6451164412ed4500d7db 479 SUPERFAMILY SSF101960 43 473 5.89E-122 T 31-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily DFR86_09365 77218c14380a6451164412ed4500d7db 479 Pfam PF01458 Uncharacterized protein family (UPF0051) 222 448 1.9E-63 T 31-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 DFR86_09365 77218c14380a6451164412ed4500d7db 479 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 33 468 7.2E-188 T 31-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 DFR86_07100 8da875a30be9e218362f1320d81c3c08 539 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 3 474 5.4E-29 T 31-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 DFR86_07100 8da875a30be9e218362f1320d81c3c08 539 SUPERFAMILY SSF53649 2 514 1.0E-43 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 DFR86_07310 977bed54557d553204da9ffcfd296042 348 Pfam PF07687 Peptidase dimerisation domain 159 247 2.5E-9 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR86_07310 977bed54557d553204da9ffcfd296042 348 SUPERFAMILY SSF55031 159 251 3.89E-10 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain DFR86_07310 977bed54557d553204da9ffcfd296042 348 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 15 343 1.4E-97 T 31-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 DFR86_07310 977bed54557d553204da9ffcfd296042 348 Gene3D G3DSA:3.30.70.360 159 259 1.6E-59 T 31-10-2018 DFR86_07310 977bed54557d553204da9ffcfd296042 348 SUPERFAMILY SSF53187 8 344 1.68E-35 T 31-10-2018 DFR86_07310 977bed54557d553204da9ffcfd296042 348 Hamap MF_01120 [LysW]-lysine/[LysW]-ornithine hydrolase [lysK]. 10 344 28.819 T 31-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 DFR86_07310 977bed54557d553204da9ffcfd296042 348 Pfam PF01546 Peptidase family M20/M25/M40 65 341 8.7E-22 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR86_07310 977bed54557d553204da9ffcfd296042 348 Gene3D G3DSA:3.40.630.10 18 329 1.6E-59 T 31-10-2018 DFR86_07310 977bed54557d553204da9ffcfd296042 348 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 64 73 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 DFR86_06250 d4824443652b379c31224c1f88ad7671 83 SUPERFAMILY SSF55287 8 81 2.09E-25 T 31-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_06250 d4824443652b379c31224c1f88ad7671 83 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 8 81 22.083 T 31-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_06250 d4824443652b379c31224c1f88ad7671 83 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 15 81 4.0E-24 T 31-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_06250 d4824443652b379c31224c1f88ad7671 83 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 13 26 - T 31-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_06250 d4824443652b379c31224c1f88ad7671 83 Gene3D G3DSA:3.90.940.20 1 83 8.0E-34 T 31-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_06250 d4824443652b379c31224c1f88ad7671 83 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 10 80 2.7E-29 T 31-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_09150 623a96c9c23c3e8c426047542e4bb238 349 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 129 2.1E-9 T 31-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 DFR86_09150 623a96c9c23c3e8c426047542e4bb238 349 Gene3D G3DSA:3.40.350.10 3 129 1.1E-10 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DFR86_09150 623a96c9c23c3e8c426047542e4bb238 349 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 282 294 - T 31-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site DFR86_09150 623a96c9c23c3e8c426047542e4bb238 349 SUPERFAMILY SSF53092 8 127 1.62E-11 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DFR86_09150 623a96c9c23c3e8c426047542e4bb238 349 Pfam PF00557 Metallopeptidase family M24 137 335 2.0E-62 T 31-10-2018 IPR000994 Peptidase M24 DFR86_09150 623a96c9c23c3e8c426047542e4bb238 349 Gene3D G3DSA:3.90.230.10 130 349 1.8E-72 T 31-10-2018 DFR86_09150 623a96c9c23c3e8c426047542e4bb238 349 SUPERFAMILY SSF55920 99 342 4.32E-67 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like DFR86_04190 106144b1c5e273c1e3e7940b1505937d 520 PIRSF PIRSF006060 5 518 2.8E-18 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04190 106144b1c5e273c1e3e7940b1505937d 520 Pfam PF13520 Amino acid permease 22 488 1.9E-36 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_03070 8d29d34b9b2b3c9d21da4450f421daef 136 SUPERFAMILY SSF55620 10 135 2.45E-28 T 31-10-2018 DFR86_03070 8d29d34b9b2b3c9d21da4450f421daef 136 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 133 5.9E-21 T 31-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 DFR86_03070 8d29d34b9b2b3c9d21da4450f421daef 136 Gene3D G3DSA:3.30.479.10 1 134 3.6E-23 T 31-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 DFR86_02480 ab4fb189fe7d4a1a25ecb17aa3967d9b 267 SUPERFAMILY SSF160240 202 262 5.23E-8 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 DFR86_02480 ab4fb189fe7d4a1a25ecb17aa3967d9b 267 Pfam PF01545 Cation efflux family 3 186 2.0E-17 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DFR86_02480 ab4fb189fe7d4a1a25ecb17aa3967d9b 267 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 265 8.7E-30 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DFR86_02480 ab4fb189fe7d4a1a25ecb17aa3967d9b 267 Gene3D G3DSA:1.20.1510.10 1 186 1.9E-10 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily DFR86_02480 ab4fb189fe7d4a1a25ecb17aa3967d9b 267 SUPERFAMILY SSF161111 4 187 5.62E-17 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily DFR86_03730 3ad58fccac98610083aefd3daa831ec3 409 Gene3D G3DSA:3.50.50.60 4 333 1.0E-101 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03730 3ad58fccac98610083aefd3daa831ec3 409 SUPERFAMILY SSF51905 120 267 3.95E-8 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03730 3ad58fccac98610083aefd3daa831ec3 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 212 324 2.5E-8 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_03730 3ad58fccac98610083aefd3daa831ec3 409 Gene3D G3DSA:3.50.50.60 115 276 1.0E-101 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03730 3ad58fccac98610083aefd3daa831ec3 409 SUPERFAMILY SSF51905 3 334 3.76E-23 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03730 3ad58fccac98610083aefd3daa831ec3 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 154 4.5E-8 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_03375 791c8d2850e6b55eea31d066a118ae3c 294 Gene3D G3DSA:3.40.50.20 3 118 1.6E-10 T 31-10-2018 DFR86_03375 791c8d2850e6b55eea31d066a118ae3c 294 Gene3D G3DSA:3.30.470.80 185 294 3.5E-35 T 31-10-2018 DFR86_03375 791c8d2850e6b55eea31d066a118ae3c 294 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 287 9.8E-61 T 31-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 DFR86_03375 791c8d2850e6b55eea31d066a118ae3c 294 SUPERFAMILY SSF56059 104 292 8.08E-46 T 31-10-2018 DFR86_03375 791c8d2850e6b55eea31d066a118ae3c 294 Gene3D G3DSA:3.30.1490.20 120 184 8.9E-6 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_03375 791c8d2850e6b55eea31d066a118ae3c 294 Pfam PF08443 RimK-like ATP-grasp domain 102 287 1.6E-29 T 31-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 464 1.7E-152 T 31-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 Pfam PF09190 DALR domain 351 410 3.1E-6 T 31-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 SUPERFAMILY SSF47323 347 465 2.16E-23 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 Gene3D G3DSA:3.40.50.620 1 301 5.2E-134 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 SUPERFAMILY SSF52374 10 308 8.31E-96 T 31-10-2018 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 SMART SM00840 351 414 3.0E-6 T 31-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 Gene3D G3DSA:1.20.120.640 302 465 1.8E-22 T 31-10-2018 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 466 34.694 T 31-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 309 2.1E-129 T 31-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 187 205 4.3E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 24 35 4.3E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 60 69 4.3E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DFR86_05185 84d6c8f3642cd4925cdc0182121056b8 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 218 239 4.3E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DFR86_08810 525cebe2a6a9dab726aa561932c2f445 538 Gene3D G3DSA:3.40.50.300 345 538 2.0E-51 T 31-10-2018 DFR86_08810 525cebe2a6a9dab726aa561932c2f445 538 Gene3D G3DSA:1.10.275.30 187 290 6.3E-94 T 31-10-2018 DFR86_08810 525cebe2a6a9dab726aa561932c2f445 538 SUPERFAMILY SSF52540 20 515 3.16E-15 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08810 525cebe2a6a9dab726aa561932c2f445 538 Gene3D G3DSA:3.40.50.300 4 329 6.3E-94 T 31-10-2018 DFR86_08810 525cebe2a6a9dab726aa561932c2f445 538 SMART SM00488 3 220 0.0012 T 31-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 DFR86_08810 525cebe2a6a9dab726aa561932c2f445 538 Pfam PF13307 Helicase C-terminal domain 376 521 2.8E-23 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 DFR86_08810 525cebe2a6a9dab726aa561932c2f445 538 SMART SM00491 393 521 2.0E-18 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 DFR86_08810 525cebe2a6a9dab726aa561932c2f445 538 Pfam PF06733 DEAD_2 118 181 2.6E-14 T 31-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 DFR86_06800 17d3cccae974f2106ebfd67c600a95c2 231 SUPERFAMILY SSF54814 8 96 5.49E-23 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 DFR86_06800 17d3cccae974f2106ebfd67c600a95c2 231 ProSitePatterns PS00548 Ribosomal protein S3 signature. 142 178 - T 31-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06800 17d3cccae974f2106ebfd67c600a95c2 231 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 4 197 2.0E-72 T 31-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06800 17d3cccae974f2106ebfd67c600a95c2 231 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 3 197 39.8 T 31-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 DFR86_06800 17d3cccae974f2106ebfd67c600a95c2 231 Gene3D G3DSA:3.30.1140.32 90 231 2.5E-33 T 31-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06800 17d3cccae974f2106ebfd67c600a95c2 231 SUPERFAMILY SSF54821 88 186 1.09E-24 T 31-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06800 17d3cccae974f2106ebfd67c600a95c2 231 Pfam PF00189 Ribosomal protein S3, C-terminal domain 101 183 1.2E-22 T 31-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06800 17d3cccae974f2106ebfd67c600a95c2 231 SMART SM00322 39 105 3.8E-4 T 31-10-2018 IPR004087 K Homology domain GO:0003676 DFR86_06800 17d3cccae974f2106ebfd67c600a95c2 231 Gene3D G3DSA:3.30.300.20 1 86 7.8E-24 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR86_06800 17d3cccae974f2106ebfd67c600a95c2 231 Pfam PF07650 KH domain 18 90 9.4E-17 T 31-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06650 62a88fe4bf6591ec64e37f1fbba47722 212 SMART SM01397 6 196 7.5E-93 T 31-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06650 62a88fe4bf6591ec64e37f1fbba47722 212 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 6 196 34.471 T 31-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 DFR86_06650 62a88fe4bf6591ec64e37f1fbba47722 212 Pfam PF01015 Ribosomal S3Ae family 9 193 2.0E-61 T 31-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_07835 3c2e5029290711a16f97d0d74c0a2e03 300 Pfam PF07849 Protein of unknown function (DUF1641) 260 296 1.7E-11 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 DFR86_06770 16d394e49d34f1e72335ace288fce178 340 Pfam PF00297 Ribosomal protein L3 1 340 5.2E-70 T 31-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06770 16d394e49d34f1e72335ace288fce178 340 Gene3D G3DSA:2.40.30.10 43 320 5.3E-105 T 31-10-2018 DFR86_06770 16d394e49d34f1e72335ace288fce178 340 Gene3D G3DSA:3.30.1430.10 82 193 5.3E-105 T 31-10-2018 DFR86_06770 16d394e49d34f1e72335ace288fce178 340 SUPERFAMILY SSF50447 4 340 2.21E-84 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR86_06770 16d394e49d34f1e72335ace288fce178 340 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 339 45.059 T 31-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06770 16d394e49d34f1e72335ace288fce178 340 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 8 338 2.2E-123 T 31-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06770 16d394e49d34f1e72335ace288fce178 340 ProSitePatterns PS00474 Ribosomal protein L3 signature. 198 221 - T 31-10-2018 IPR019926 Ribosomal protein L3, conserved site DFR86_06770 16d394e49d34f1e72335ace288fce178 340 Gene3D G3DSA:4.10.960.10 9 260 5.3E-105 T 31-10-2018 DFR86_07455 fa3183347756550b870b7e3d149d548c 614 SUPERFAMILY SSF56801 8 604 1.07E-150 T 31-10-2018 DFR86_07455 fa3183347756550b870b7e3d149d548c 614 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 10 62 1.2E-19 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR86_07455 fa3183347756550b870b7e3d149d548c 614 ProSitePatterns PS00455 Putative AMP-binding domain signature. 226 237 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR86_07455 fa3183347756550b870b7e3d149d548c 614 Pfam PF13193 AMP-binding enzyme C-terminal domain 496 574 2.5E-20 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR86_07455 fa3183347756550b870b7e3d149d548c 614 Gene3D G3DSA:3.40.50.12780 33 480 1.2E-97 T 31-10-2018 DFR86_07455 fa3183347756550b870b7e3d149d548c 614 Pfam PF00501 AMP-binding enzyme 66 487 1.6E-86 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR86_07455 fa3183347756550b870b7e3d149d548c 614 Gene3D G3DSA:3.30.300.30 483 610 2.0E-29 T 31-10-2018 DFR86_01745 c354f6ff3d0772d62728180f6ab26c35 247 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 246 7.2E-88 T 31-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 DFR86_01745 c354f6ff3d0772d62728180f6ab26c35 247 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 239 4.1E-22 T 31-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase DFR86_01745 c354f6ff3d0772d62728180f6ab26c35 247 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 246 1.3E-83 T 31-10-2018 DFR86_01745 c354f6ff3d0772d62728180f6ab26c35 247 SUPERFAMILY SSF56219 1 246 1.83E-72 T 31-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily DFR86_01745 c354f6ff3d0772d62728180f6ab26c35 247 Gene3D G3DSA:3.60.10.10 1 247 1.6E-85 T 31-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily DFR86_01745 c354f6ff3d0772d62728180f6ab26c35 247 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 207 218 - T 31-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 DFR86_05030 a5cd071a364dc37607348b7765a01109 145 Gene3D G3DSA:3.10.590.10 1 143 5.8E-37 T 31-10-2018 DFR86_05030 a5cd071a364dc37607348b7765a01109 145 Pfam PF01878 EVE domain 2 141 1.9E-20 T 31-10-2018 IPR002740 EVE domain DFR86_05030 a5cd071a364dc37607348b7765a01109 145 SUPERFAMILY SSF88697 2 141 1.49E-30 T 31-10-2018 IPR015947 PUA-like superfamily DFR86_03560 0dd14361a73a62eb69660759bf5a8779 399 Gene3D G3DSA:1.20.1250.20 4 391 7.6E-54 T 31-10-2018 DFR86_03560 0dd14361a73a62eb69660759bf5a8779 399 ProSitePatterns PS00217 Sugar transport proteins signature 2. 103 128 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_03560 0dd14361a73a62eb69660759bf5a8779 399 SUPERFAMILY SSF103473 7 381 1.7E-54 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_03560 0dd14361a73a62eb69660759bf5a8779 399 Pfam PF07690 Major Facilitator Superfamily 24 346 8.3E-35 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_09075 db6cc6160cf3c1dde6e9f76e2837488b 173 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 169 6.0E-62 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR86_09075 db6cc6160cf3c1dde6e9f76e2837488b 173 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 170 4.6E-57 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR86_09075 db6cc6160cf3c1dde6e9f76e2837488b 173 Pfam PF01923 Cobalamin adenosyltransferase 4 157 1.7E-44 T 31-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR86_09075 db6cc6160cf3c1dde6e9f76e2837488b 173 Gene3D G3DSA:1.20.1200.10 23 172 2.1E-51 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR86_09075 db6cc6160cf3c1dde6e9f76e2837488b 173 SUPERFAMILY SSF89028 2 170 4.12E-49 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 PRINTS PR00148 Enolase signature 328 342 1.3E-35 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 PRINTS PR00148 Enolase signature 158 171 1.3E-35 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 PRINTS PR00148 Enolase signature 305 316 1.3E-35 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 PRINTS PR00148 Enolase signature 40 54 1.3E-35 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 PRINTS PR00148 Enolase signature 104 120 1.3E-35 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 PRINTS PR00148 Enolase signature 357 374 1.3E-35 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 SMART SM01192 136 412 5.1E-150 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 Pfam PF00113 Enolase, C-terminal TIM barrel domain 137 405 2.6E-96 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 SUPERFAMILY SSF54826 7 133 1.77E-37 T 31-10-2018 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 PIRSF PIRSF001400 3 412 6.9E-165 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 Gene3D G3DSA:3.20.20.120 125 412 9.6E-113 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 Pfam PF03952 Enolase, N-terminal domain 7 131 6.1E-40 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 404 7.1E-146 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 SMART SM01193 7 131 8.0E-54 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 ProSitePatterns PS00164 Enolase signature. 328 341 - T 31-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 Gene3D G3DSA:3.30.390.10 5 124 2.0E-39 T 31-10-2018 IPR029017 Enolase-like, N-terminal DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 SUPERFAMILY SSF51604 137 404 7.92E-103 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR86_09425 161229e5f1a27f71e22420f6a1788491 413 Hamap MF_00318 Enolase [eno]. 5 405 39.147 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_04465 4759b83475aef339b0912e76ce14521f 288 SUPERFAMILY SSF161098 82 257 9.05E-17 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_04465 4759b83475aef339b0912e76ce14521f 288 Gene3D G3DSA:1.10.3720.10 70 285 2.5E-13 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_04465 4759b83475aef339b0912e76ce14521f 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 285 9.8E-25 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_01805 5a046953dca6626daf5997bc35d88494 72 Gene3D G3DSA:1.10.1220.10 18 60 1.0E-10 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DFR86_01805 5a046953dca6626daf5997bc35d88494 72 SUPERFAMILY SSF47598 20 60 3.51E-10 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR86_01805 5a046953dca6626daf5997bc35d88494 72 Pfam PF01402 Ribbon-helix-helix protein, copG family 22 57 7.9E-8 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR86_02610 9241f886a0b89ada1a84f9a2846593ea 250 SUPERFAMILY SSF53335 16 213 1.39E-35 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_02610 9241f886a0b89ada1a84f9a2846593ea 250 Pfam PF02475 Met-10+ like-protein 17 209 3.0E-28 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 DFR86_02610 9241f886a0b89ada1a84f9a2846593ea 250 Gene3D G3DSA:3.30.300.110 2 74 3.2E-10 T 31-10-2018 DFR86_02610 9241f886a0b89ada1a84f9a2846593ea 250 Gene3D G3DSA:3.40.50.150 75 246 7.0E-24 T 31-10-2018 DFR86_11045 a107537b6ac20be0ce7d5f04a16f7bee 91 Pfam PF02635 DsrE/DsrF-like family 15 71 7.8E-5 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR86_11045 a107537b6ac20be0ce7d5f04a16f7bee 91 SUPERFAMILY SSF75169 5 90 6.67E-15 T 31-10-2018 IPR027396 DsrEFH-like DFR86_07385 3ffcc07ab48d14aa8b8a7e8f3f807631 292 Gene3D G3DSA:3.30.465.40 42 166 5.2E-9 T 31-10-2018 DFR86_07385 3ffcc07ab48d14aa8b8a7e8f3f807631 292 SUPERFAMILY SSF56176 2 154 1.64E-12 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_07385 3ffcc07ab48d14aa8b8a7e8f3f807631 292 Pfam PF01565 FAD binding domain 2 118 9.9E-9 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_03460 28585497ff3f76b8f076ed02789ee719 306 SMART SM00382 30 221 4.7E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_03460 28585497ff3f76b8f076ed02789ee719 306 Gene3D G3DSA:3.40.50.300 2 267 2.6E-62 T 31-10-2018 DFR86_03460 28585497ff3f76b8f076ed02789ee719 306 SUPERFAMILY SSF52540 11 228 1.3E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03460 28585497ff3f76b8f076ed02789ee719 306 Pfam PF00005 ABC transporter 21 165 9.5E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_05505 c783d10df86aa8422333c36654f4d28d 386 SUPERFAMILY SSF53218 173 311 7.59E-26 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR86_05505 c783d10df86aa8422333c36654f4d28d 386 SMART SM00852 175 308 1.0E-21 T 31-10-2018 IPR001453 MoaB/Mog domain DFR86_05505 c783d10df86aa8422333c36654f4d28d 386 Gene3D G3DSA:2.40.340.10 316 377 1.2E-75 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_05505 c783d10df86aa8422333c36654f4d28d 386 Gene3D G3DSA:2.170.190.11 47 137 1.2E-75 T 31-10-2018 DFR86_05505 c783d10df86aa8422333c36654f4d28d 386 Gene3D G3DSA:3.40.980.10 171 315 1.2E-75 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR86_05505 c783d10df86aa8422333c36654f4d28d 386 SUPERFAMILY SSF63882 3 170 7.98E-43 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_05505 c783d10df86aa8422333c36654f4d28d 386 Pfam PF00994 Probable molybdopterin binding domain 176 302 1.1E-16 T 31-10-2018 IPR001453 MoaB/Mog domain DFR86_05505 c783d10df86aa8422333c36654f4d28d 386 Gene3D G3DSA:3.90.105.10 24 170 1.2E-75 T 31-10-2018 DFR86_05505 c783d10df86aa8422333c36654f4d28d 386 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 160 9.0E-37 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_04435 a697d00df7cf545dfe3ce8ac1c7892a7 328 SUPERFAMILY SSF51658 17 322 1.52E-57 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily DFR86_04435 a697d00df7cf545dfe3ce8ac1c7892a7 328 Gene3D G3DSA:3.20.20.150 17 328 9.0E-92 T 31-10-2018 DFR86_04435 a697d00df7cf545dfe3ce8ac1c7892a7 328 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 146 3.8E-27 T 31-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 DFR86_04435 a697d00df7cf545dfe3ce8ac1c7892a7 328 Pfam PF03786 D-mannonate dehydratase (UxuA) 149 324 1.1E-62 T 31-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 DFR86_04435 a697d00df7cf545dfe3ce8ac1c7892a7 328 PIRSF PIRSF016049 136 328 7.6E-67 T 31-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 DFR86_04435 a697d00df7cf545dfe3ce8ac1c7892a7 328 PIRSF PIRSF016049 2 150 1.1E-25 T 31-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 DFR86_03865 a21381968ef039aedafd0d3de9df5032 105 Pfam PF07849 Protein of unknown function (DUF1641) 67 101 2.0E-7 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 DFR86_04810 1c380f138edda3e69768a79970c34304 431 PIRSF PIRSF001413 10 431 4.8E-145 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_04810 1c380f138edda3e69768a79970c34304 431 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 14 427 1.8E-196 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_04810 1c380f138edda3e69768a79970c34304 431 PIRSF PIRSF500824 2 431 8.9E-191 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_04810 1c380f138edda3e69768a79970c34304 431 Gene3D G3DSA:3.40.50.1100 14 419 6.4E-156 T 31-10-2018 DFR86_04810 1c380f138edda3e69768a79970c34304 431 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 104 118 - T 31-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_04810 1c380f138edda3e69768a79970c34304 431 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 22 426 38.115 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_04810 1c380f138edda3e69768a79970c34304 431 Gene3D G3DSA:3.40.50.1100 15 236 6.4E-156 T 31-10-2018 DFR86_04810 1c380f138edda3e69768a79970c34304 431 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 74 413 1.6E-38 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR86_04810 1c380f138edda3e69768a79970c34304 431 SUPERFAMILY SSF53686 47 425 7.82E-93 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 Gene3D G3DSA:1.25.40.10 166 273 8.3E-13 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 Pfam PF13432 Tetratricopeptide repeat 7 61 0.003 T 31-10-2018 DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 SMART SM00028 98 131 10.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 SMART SM00028 200 233 1.3 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 SMART SM00028 166 199 110.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 SMART SM00028 30 63 0.35 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 SMART SM00028 64 97 0.64 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 SMART SM00028 132 165 30.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 Gene3D G3DSA:1.25.40.10 3 165 3.8E-27 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 SUPERFAMILY SSF48452 4 234 1.9E-27 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_00315 4b43dcdfcf2bfd8e5352335ce63ac83b 274 Pfam PF14559 Tetratricopeptide repeat 110 175 3.9E-6 T 31-10-2018 DFR86_05800 c3d9d4b82256ad66a99380184158ee6a 171 Gene3D G3DSA:4.10.910.10 88 138 1.3E-19 T 31-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05800 c3d9d4b82256ad66a99380184158ee6a 171 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 148 23.433 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05800 c3d9d4b82256ad66a99380184158ee6a 171 SUPERFAMILY SSF46946 9 144 6.67E-31 T 31-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 DFR86_05800 c3d9d4b82256ad66a99380184158ee6a 171 Gene3D G3DSA:1.10.8.50 1 76 3.2E-24 T 31-10-2018 DFR86_05800 c3d9d4b82256ad66a99380184158ee6a 171 Pfam PF00416 Ribosomal protein S13/S18 10 137 6.3E-48 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05800 c3d9d4b82256ad66a99380184158ee6a 171 PIRSF PIRSF002134 1 154 7.3E-42 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05800 c3d9d4b82256ad66a99380184158ee6a 171 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 5 146 7.1E-58 T 31-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05800 c3d9d4b82256ad66a99380184158ee6a 171 ProSitePatterns PS00646 Ribosomal protein S13 signature. 117 130 - T 31-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_03105 b4c0ad198358c319d2c72d520563b6b6 207 Gene3D G3DSA:3.60.15.10 1 206 4.4E-50 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_03105 b4c0ad198358c319d2c72d520563b6b6 207 Pfam PF13483 Beta-lactamase superfamily domain 2 160 2.0E-34 T 31-10-2018 DFR86_03105 b4c0ad198358c319d2c72d520563b6b6 207 SUPERFAMILY SSF56281 2 188 3.64E-29 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_01770 f44c71a33a92b364e1392546642795fd 325 Pfam PF02272 DHHA1 domain 189 280 3.9E-9 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 DFR86_01770 f44c71a33a92b364e1392546642795fd 325 SUPERFAMILY SSF64182 6 290 3.01E-24 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily DFR86_01770 f44c71a33a92b364e1392546642795fd 325 Gene3D G3DSA:3.10.310.30 211 291 3.9E-9 T 31-10-2018 DFR86_04505 c8fb4ddeca6e81b15b2d6183ecb61256 775 SUPERFAMILY SSF53850 389 641 5.79E-12 T 31-10-2018 DFR86_04505 c8fb4ddeca6e81b15b2d6183ecb61256 775 SUPERFAMILY SSF53850 55 362 5.43E-38 T 31-10-2018 DFR86_04505 c8fb4ddeca6e81b15b2d6183ecb61256 775 Gene3D G3DSA:3.10.105.10 114 340 3.4E-30 T 31-10-2018 DFR86_04505 c8fb4ddeca6e81b15b2d6183ecb61256 775 Gene3D G3DSA:3.40.190.10 58 346 3.4E-30 T 31-10-2018 DFR86_04505 c8fb4ddeca6e81b15b2d6183ecb61256 775 Gene3D G3DSA:3.40.190.10 378 655 3.7E-16 T 31-10-2018 DFR86_04505 c8fb4ddeca6e81b15b2d6183ecb61256 775 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 59 290 8.4E-18 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain DFR86_04505 c8fb4ddeca6e81b15b2d6183ecb61256 775 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 434 646 2.1E-9 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain DFR86_00580 8ba2a72a1ecfeab2147eb3fcbc1af628 132 SUPERFAMILY SSF50249 8 117 5.31E-29 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_00580 8ba2a72a1ecfeab2147eb3fcbc1af628 132 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 22 58 2.2E-12 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DFR86_00580 8ba2a72a1ecfeab2147eb3fcbc1af628 132 Gene3D G3DSA:1.10.12.20 5 62 4.1E-16 T 31-10-2018 DFR86_00580 8ba2a72a1ecfeab2147eb3fcbc1af628 132 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 59 117 2.6E-9 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DFR86_08105 33ba23d93721d17ee6f1f002659bd50e 457 SUPERFAMILY SSF52540 1 222 3.79E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08105 33ba23d93721d17ee6f1f002659bd50e 457 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 234 413 2.5E-38 T 31-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 DFR86_08105 33ba23d93721d17ee6f1f002659bd50e 457 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 215 1.2E-12 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DFR86_08105 33ba23d93721d17ee6f1f002659bd50e 457 Gene3D G3DSA:3.40.50.300 1 227 1.7E-31 T 31-10-2018 DFR86_08105 33ba23d93721d17ee6f1f002659bd50e 457 Gene3D G3DSA:3.40.50.880 232 413 3.5E-22 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_08105 33ba23d93721d17ee6f1f002659bd50e 457 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 457 96.28 T 31-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 DFR86_08105 33ba23d93721d17ee6f1f002659bd50e 457 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 3 419 3.4E-98 T 31-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 DFR86_08105 33ba23d93721d17ee6f1f002659bd50e 457 SUPERFAMILY SSF52317 176 382 3.67E-29 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_10480 b800aed225023a75613208d408d85ff7 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 82 183 4.8E-10 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR86_10480 b800aed225023a75613208d408d85ff7 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 134 150 3.4E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR86_10480 b800aed225023a75613208d408d85ff7 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 3.4E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR86_10480 b800aed225023a75613208d408d85ff7 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 178 191 3.4E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR86_10480 b800aed225023a75613208d408d85ff7 216 Gene3D G3DSA:1.10.150.660 15 90 5.5E-70 T 31-10-2018 DFR86_10480 b800aed225023a75613208d408d85ff7 216 SUPERFAMILY SSF56784 4 197 3.16E-25 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_10480 b800aed225023a75613208d408d85ff7 216 Gene3D G3DSA:3.40.50.1000 4 209 5.5E-70 T 31-10-2018 IPR023214 HAD superfamily DFR86_10480 b800aed225023a75613208d408d85ff7 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 27 188 1.9E-12 T 31-10-2018 DFR86_06075 994e49f1b478392238f788289c6f87bf 129 Hamap MF_00785 Sirohydrochlorin cobaltochelatase [cbiX]. 1 122 25.976 T 31-10-2018 IPR023652 Sirohydrochlorin cobaltochelatase GO:0016852|GO:0050897 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 DFR86_06075 994e49f1b478392238f788289c6f87bf 129 SUPERFAMILY SSF53800 1 122 5.1E-28 T 31-10-2018 DFR86_06075 994e49f1b478392238f788289c6f87bf 129 Pfam PF01903 CbiX 9 117 8.7E-25 T 31-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 DFR86_06075 994e49f1b478392238f788289c6f87bf 129 Gene3D G3DSA:3.40.50.1400 2 127 5.4E-28 T 31-10-2018 DFR86_03725 34a6fbce3cd959b701a6bd0ef814d1b3 115 SUPERFAMILY SSF75169 4 115 4.94E-6 T 31-10-2018 IPR027396 DsrEFH-like DFR86_03725 34a6fbce3cd959b701a6bd0ef814d1b3 115 Gene3D G3DSA:3.40.1260.10 2 115 5.1E-16 T 31-10-2018 IPR027396 DsrEFH-like DFR86_03725 34a6fbce3cd959b701a6bd0ef814d1b3 115 Pfam PF02635 DsrE/DsrF-like family 4 115 1.9E-7 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR86_06775 1818a99dc83e89449aceb3602f197823 265 SUPERFAMILY SSF52166 9 258 9.55E-66 T 31-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_06775 1818a99dc83e89449aceb3602f197823 265 Pfam PF00573 Ribosomal protein L4/L1 family 23 258 1.7E-39 T 31-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 DFR86_06775 1818a99dc83e89449aceb3602f197823 265 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 9 259 41.509 T 31-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 DFR86_06775 1818a99dc83e89449aceb3602f197823 265 Gene3D G3DSA:3.40.1370.10 4 263 1.5E-89 T 31-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_06775 1818a99dc83e89449aceb3602f197823 265 ProSitePatterns PS00939 Ribosomal protein L1e signature. 112 138 - T 31-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06775 1818a99dc83e89449aceb3602f197823 265 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 8 258 1.2E-104 T 31-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 DFR86_10495 80c2d796610ae3363f37b0b714a5f4c6 526 SUPERFAMILY SSF52540 4 235 3.79E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_10495 80c2d796610ae3363f37b0b714a5f4c6 526 SMART SM00382 305 490 1.8E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_10495 80c2d796610ae3363f37b0b714a5f4c6 526 SMART SM00382 30 229 4.1E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_10495 80c2d796610ae3363f37b0b714a5f4c6 526 Gene3D G3DSA:3.40.50.300 282 512 3.5E-54 T 31-10-2018 DFR86_10495 80c2d796610ae3363f37b0b714a5f4c6 526 Pfam PF00005 ABC transporter 26 172 2.3E-23 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_10495 80c2d796610ae3363f37b0b714a5f4c6 526 Pfam PF00005 ABC transporter 298 442 4.5E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_10495 80c2d796610ae3363f37b0b714a5f4c6 526 SUPERFAMILY SSF52540 288 503 3.11E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_10495 80c2d796610ae3363f37b0b714a5f4c6 526 Gene3D G3DSA:3.40.50.300 2 261 1.5E-57 T 31-10-2018 DFR86_02560 55aec06b568bddf1b1dcd70a8f29cae6 172 SUPERFAMILY SSF52972 1 168 4.36E-43 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like DFR86_02560 55aec06b568bddf1b1dcd70a8f29cae6 172 Hamap MF_00648 Non-canonical purine NTP phosphatase. 1 170 27.298 T 31-10-2018 IPR002786 Non-canonical purine NTP phosphatase DFR86_02560 55aec06b568bddf1b1dcd70a8f29cae6 172 Gene3D G3DSA:3.90.950.10 1 169 8.3E-46 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like DFR86_02560 55aec06b568bddf1b1dcd70a8f29cae6 172 Pfam PF01931 Protein of unknown function DUF84 6 164 2.7E-47 T 31-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 DFR86_07945 b9f9783b4bbf18ac61c2bb3c47626b80 710 Gene3D G3DSA:3.20.20.80 147 594 7.7E-178 T 31-10-2018 DFR86_07945 b9f9783b4bbf18ac61c2bb3c47626b80 710 Gene3D G3DSA:2.60.40.1180 604 710 2.6E-35 T 31-10-2018 IPR013780 Glycosyl hydrolase, all-beta DFR86_07945 b9f9783b4bbf18ac61c2bb3c47626b80 710 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 11 708 0.0 T 31-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 DFR86_07945 b9f9783b4bbf18ac61c2bb3c47626b80 710 SUPERFAMILY SSF51011 602 707 2.45E-13 T 31-10-2018 DFR86_07945 b9f9783b4bbf18ac61c2bb3c47626b80 710 SUPERFAMILY SSF81296 10 157 2.8E-45 T 31-10-2018 IPR014756 Immunoglobulin E-set DFR86_07945 b9f9783b4bbf18ac61c2bb3c47626b80 710 SMART SM00642 171 580 7.2E-9 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR86_07945 b9f9783b4bbf18ac61c2bb3c47626b80 710 SUPERFAMILY SSF51445 144 587 3.36E-129 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR86_07945 b9f9783b4bbf18ac61c2bb3c47626b80 710 Pfam PF00128 Alpha amylase, catalytic domain 195 289 1.7E-8 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR86_07945 b9f9783b4bbf18ac61c2bb3c47626b80 710 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 15 104 1.6E-17 T 31-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 DFR86_07945 b9f9783b4bbf18ac61c2bb3c47626b80 710 Gene3D G3DSA:2.60.40.10 3 146 3.4E-51 T 31-10-2018 IPR013783 Immunoglobulin-like fold DFR86_04420 94b0237434e566d48d5ea950a6ce4e88 385 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 187 218 - T 31-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 DFR86_04420 94b0237434e566d48d5ea950a6ce4e88 385 SMART SM00922 132 237 3.5E-23 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DFR86_04420 94b0237434e566d48d5ea950a6ce4e88 385 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 19 111 2.8E-18 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DFR86_04420 94b0237434e566d48d5ea950a6ce4e88 385 Gene3D G3DSA:3.20.20.120 106 345 1.6E-125 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR86_04420 94b0237434e566d48d5ea950a6ce4e88 385 SUPERFAMILY SSF54826 3 116 5.39E-28 T 31-10-2018 DFR86_04420 94b0237434e566d48d5ea950a6ce4e88 385 SUPERFAMILY SSF51604 99 364 4.72E-75 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR86_04420 94b0237434e566d48d5ea950a6ce4e88 385 Gene3D G3DSA:3.30.390.10 7 365 1.6E-125 T 31-10-2018 IPR029017 Enolase-like, N-terminal DFR86_04420 94b0237434e566d48d5ea950a6ce4e88 385 Pfam PF13378 Enolase C-terminal domain-like 138 356 1.4E-60 T 31-10-2018 IPR029065 Enolase C-terminal domain-like DFR86_05145 ca26efc6d073db6e1c6a75d0560a6ff2 369 SUPERFAMILY SSF103473 3 359 2.22E-22 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_05145 ca26efc6d073db6e1c6a75d0560a6ff2 369 Gene3D G3DSA:1.20.1250.20 3 364 3.9E-17 T 31-10-2018 DFR86_05145 ca26efc6d073db6e1c6a75d0560a6ff2 369 Pfam PF07690 Major Facilitator Superfamily 4 328 1.0E-12 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_05455 845613b17df8bf90f8be6acfe00231bb 172 Gene3D G3DSA:3.40.50.12280 9 171 2.7E-53 T 31-10-2018 DFR86_05455 845613b17df8bf90f8be6acfe00231bb 172 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 67 159 1.1E-22 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_05455 845613b17df8bf90f8be6acfe00231bb 172 SUPERFAMILY SSF56770 28 168 5.36E-51 T 31-10-2018 DFR86_05455 845613b17df8bf90f8be6acfe00231bb 172 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 30 166 2.9E-47 T 31-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_10470 802889799ea97302a75073b373cd17d0 122 Pfam PF05168 HEPN domain 4 116 9.1E-19 T 31-10-2018 IPR007842 HEPN domain DFR86_10470 802889799ea97302a75073b373cd17d0 122 SMART SM00748 7 112 0.0012 T 31-10-2018 IPR007842 HEPN domain DFR86_10470 802889799ea97302a75073b373cd17d0 122 SUPERFAMILY SSF81593 5 118 1.02E-16 T 31-10-2018 DFR86_10470 802889799ea97302a75073b373cd17d0 122 Gene3D G3DSA:1.20.120.330 1 119 3.3E-12 T 31-10-2018 DFR86_09375 88dd1a9e17f9a35d2500c4050a590a13 335 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 22 64 3.4E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_09375 88dd1a9e17f9a35d2500c4050a590a13 335 SUPERFAMILY SSF89447 17 58 3.14E-5 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR86_09375 88dd1a9e17f9a35d2500c4050a590a13 335 SMART SM00966 20 66 6.0E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_09970 d5bbb13f905e9070f471d4e54fab71e9 333 SUPERFAMILY SSF63825 13 115 3.4E-12 T 31-10-2018 DFR86_09970 d5bbb13f905e9070f471d4e54fab71e9 333 Gene3D G3DSA:2.130.10.10 9 66 2.1E-8 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_09970 d5bbb13f905e9070f471d4e54fab71e9 333 Gene3D G3DSA:2.130.10.10 67 188 6.5E-10 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_09970 d5bbb13f905e9070f471d4e54fab71e9 333 SUPERFAMILY SSF63825 85 288 6.28E-25 T 31-10-2018 DFR86_09970 d5bbb13f905e9070f471d4e54fab71e9 333 Gene3D G3DSA:2.120.10.30 189 290 2.4E-8 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like DFR86_09970 d5bbb13f905e9070f471d4e54fab71e9 333 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 30 65 3.1E-9 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_04090 6b1f710db748e066d0eb69c113a07148 255 Gene3D G3DSA:2.60.40.420 87 253 1.8E-39 T 31-10-2018 IPR008972 Cupredoxin DFR86_04090 6b1f710db748e066d0eb69c113a07148 255 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 218 253 1.7E-4 T 31-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 DFR86_04090 6b1f710db748e066d0eb69c113a07148 255 ProSitePatterns PS00079 Multicopper oxidases signature 1. 231 251 - T 31-10-2018 IPR033138 Multicopper oxidases, conserved site DFR86_04090 6b1f710db748e066d0eb69c113a07148 255 SUPERFAMILY SSF49503 155 253 2.39E-14 T 31-10-2018 IPR008972 Cupredoxin DFR86_04090 6b1f710db748e066d0eb69c113a07148 255 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 231 247 - T 31-10-2018 IPR028871 Blue (type 1) copper protein, binding site DFR86_08885 5b0a0295f1f9b49b4a50c6d9ce7e525f 331 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 38 281 4.8E-9 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD DFR86_10055 78cffdf37bfc180c08c880e5611703b1 337 SUPERFAMILY SSF53686 4 335 2.88E-71 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR86_10055 78cffdf37bfc180c08c880e5611703b1 337 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 50 321 2.1E-59 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR86_10055 78cffdf37bfc180c08c880e5611703b1 337 Gene3D G3DSA:3.40.50.1100 48 336 1.6E-76 T 31-10-2018 DFR86_10055 78cffdf37bfc180c08c880e5611703b1 337 Gene3D G3DSA:3.40.50.1100 79 171 1.6E-76 T 31-10-2018 DFR86_09095 28cf84a6a89ae88888e1a2f6ff8e3365 288 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 11 283 48.043 T 31-10-2018 IPR033686 Tyrosine recombinase XerA DFR86_09095 28cf84a6a89ae88888e1a2f6ff8e3365 288 Pfam PF00589 Phage integrase family 118 270 5.3E-38 T 31-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DFR86_09095 28cf84a6a89ae88888e1a2f6ff8e3365 288 Gene3D G3DSA:1.10.443.10 109 286 5.1E-53 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 DFR86_09095 28cf84a6a89ae88888e1a2f6ff8e3365 288 SUPERFAMILY SSF56349 13 279 2.65E-52 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DFR86_09095 28cf84a6a89ae88888e1a2f6ff8e3365 288 Gene3D G3DSA:1.10.150.130 10 106 6.1E-11 T 31-10-2018 IPR010998 Integrase/recombinase, N-terminal DFR86_09095 28cf84a6a89ae88888e1a2f6ff8e3365 288 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 15 70 2.0E-8 T 31-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 DFR86_01860 a920a554dc5a663cc4e8b41db89a1d6d 133 Gene3D G3DSA:3.30.530.20 1 133 1.0E-44 T 31-10-2018 IPR023393 START-like domain superfamily DFR86_01860 a920a554dc5a663cc4e8b41db89a1d6d 133 Pfam PF11485 Protein of unknown function (DUF3211) 1 133 3.9E-42 T 31-10-2018 IPR021578 Protein of unknown function DUF3211 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 149 284 1.3E-43 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 SUPERFAMILY SSF51735 3 137 3.08E-36 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 Gene3D G3DSA:3.40.50.261 289 446 3.3E-28 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 Gene3D G3DSA:3.30.1490.20 481 548 6.6E-55 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 SUPERFAMILY SSF52210 291 440 1.96E-27 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 SMART SM00881 6 100 2.3E-35 T 31-10-2018 IPR003781 CoA-binding GO:0048037 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 Pfam PF13549 ATP-grasp domain 456 659 4.6E-49 T 31-10-2018 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 SUPERFAMILY SSF56059 463 660 2.65E-37 T 31-10-2018 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 Gene3D G3DSA:3.30.470.20 462 658 6.6E-55 T 31-10-2018 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 SUPERFAMILY SSF52210 137 283 1.11E-34 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 Pfam PF13380 CoA binding domain 10 134 1.7E-23 T 31-10-2018 IPR003781 CoA-binding GO:0048037 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 Gene3D G3DSA:3.40.50.720 2 129 2.3E-43 T 31-10-2018 DFR86_01605 849c00e62e305f37b090330ccd4ea792 660 Gene3D G3DSA:3.40.50.261 133 287 3.0E-47 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_10125 884f4775de3651f3042a1fcf02c82d19 207 Gene3D G3DSA:1.10.340.30 12 126 6.0E-23 T 31-10-2018 DFR86_10125 884f4775de3651f3042a1fcf02c82d19 207 Gene3D G3DSA:1.10.1670.10 127 207 3.4E-9 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 DFR86_10125 884f4775de3651f3042a1fcf02c82d19 207 SMART SM00478 29 181 3.4E-12 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 DFR86_10125 884f4775de3651f3042a1fcf02c82d19 207 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 25 161 2.1E-9 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 DFR86_10125 884f4775de3651f3042a1fcf02c82d19 207 SUPERFAMILY SSF48150 8 202 8.95E-37 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 DFR86_10125 884f4775de3651f3042a1fcf02c82d19 207 PIRSF PIRSF001435 1 206 2.7E-49 T 31-10-2018 DFR86_06270 d89b7b26dc276d6dce1f77b436b3a209 63 ProSitePatterns PS01073 Ribosomal protein L24e signature. 10 27 - T 31-10-2018 IPR023442 Ribosomal protein L24e, conserved site DFR86_06270 d89b7b26dc276d6dce1f77b436b3a209 63 Gene3D G3DSA:2.30.170.20 3 63 1.1E-26 T 31-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily DFR86_06270 d89b7b26dc276d6dce1f77b436b3a209 63 SMART SM00746 8 46 2.2E-12 T 31-10-2018 IPR011017 TRASH domain DFR86_06270 d89b7b26dc276d6dce1f77b436b3a209 63 SUPERFAMILY SSF57716 7 58 5.06E-18 T 31-10-2018 DFR86_06270 d89b7b26dc276d6dce1f77b436b3a209 63 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 3 57 27.54 T 31-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06270 d89b7b26dc276d6dce1f77b436b3a209 63 Pfam PF01246 Ribosomal protein L24e 5 62 4.6E-22 T 31-10-2018 IPR000988 Ribosomal protein L24e-related DFR86_03630 586cc32d9771573512aea406ff761767 268 SUPERFAMILY SSF54001 14 247 7.99E-36 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily DFR86_03630 586cc32d9771573512aea406ff761767 268 SMART SM00460 162 221 7.2E-15 T 31-10-2018 IPR002931 Transglutaminase-like DFR86_03630 586cc32d9771573512aea406ff761767 268 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 7 85 8.4E-12 T 31-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal DFR86_03630 586cc32d9771573512aea406ff761767 268 Gene3D G3DSA:3.10.620.30 79 256 1.3E-41 T 31-10-2018 DFR86_03630 586cc32d9771573512aea406ff761767 268 Pfam PF01841 Transglutaminase-like superfamily 120 219 6.9E-20 T 31-10-2018 IPR002931 Transglutaminase-like DFR86_10835 ba211237787667c8462980d5e88d0ae8 345 SUPERFAMILY SSF55681 14 249 7.81E-50 T 31-10-2018 DFR86_10835 ba211237787667c8462980d5e88d0ae8 345 Gene3D G3DSA:3.30.930.10 9 253 2.7E-48 T 31-10-2018 DFR86_10835 ba211237787667c8462980d5e88d0ae8 345 SUPERFAMILY SSF82649 263 340 5.02E-9 T 31-10-2018 DFR86_10835 ba211237787667c8462980d5e88d0ae8 345 Gene3D G3DSA:3.30.390.50 257 341 2.5E-20 T 31-10-2018 DFR86_03315 2c342e8e1ea29ff8cb75950b694b044a 318 Gene3D G3DSA:3.10.20.30 6 111 1.8E-32 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR86_03315 2c342e8e1ea29ff8cb75950b694b044a 318 Gene3D G3DSA:1.10.1060.10 113 250 6.1E-36 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_03315 2c342e8e1ea29ff8cb75950b694b044a 318 Pfam PF13183 4Fe-4S dicluster domain 152 223 1.7E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_03315 2c342e8e1ea29ff8cb75950b694b044a 318 SUPERFAMILY SSF54292 7 111 3.85E-26 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR86_03315 2c342e8e1ea29ff8cb75950b694b044a 318 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 209 220 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_03315 2c342e8e1ea29ff8cb75950b694b044a 318 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DFR86_03315 2c342e8e1ea29ff8cb75950b694b044a 318 SUPERFAMILY SSF46548 113 235 1.01E-30 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_03315 2c342e8e1ea29ff8cb75950b694b044a 318 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 155 166 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_03315 2c342e8e1ea29ff8cb75950b694b044a 318 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 13 233 1.0E-65 T 31-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_03315 2c342e8e1ea29ff8cb75950b694b044a 318 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 11 116 1.2E-33 T 31-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_10705 9a3647de425adc3ad0ea58b533770318 54 Gene3D G3DSA:1.10.620.20 1 49 6.6E-12 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR86_10705 9a3647de425adc3ad0ea58b533770318 54 Pfam PF04945 YHS domain 1 45 6.1E-20 T 31-10-2018 IPR007029 YHS domain DFR86_10705 9a3647de425adc3ad0ea58b533770318 54 SUPERFAMILY SSF47240 1 43 8.11E-10 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR86_10705 9a3647de425adc3ad0ea58b533770318 54 SMART SM00746 3 40 7.2E-11 T 31-10-2018 IPR011017 TRASH domain DFR86_03480 3c32648fb3e5f9f058afe61d904d996f 154 Gene3D G3DSA:3.40.50.300 2 139 4.6E-14 T 31-10-2018 DFR86_03480 3c32648fb3e5f9f058afe61d904d996f 154 SUPERFAMILY SSF52540 1 131 8.17E-14 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03480 3c32648fb3e5f9f058afe61d904d996f 154 Pfam PF13614 AAA domain 4 129 6.4E-9 T 31-10-2018 IPR025669 AAA domain DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 516 1115 0.0 T 31-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 ProSitePatterns PS01166 RNA polymerases beta chain signature. 871 883 - T 31-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Gene3D G3DSA:3.90.1100.10 11 171 1.3E-11 T 31-10-2018 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Pfam PF04563 RNA polymerase beta subunit 19 388 2.2E-57 T 31-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Pfam PF04565 RNA polymerase Rpb2, domain 3 409 473 1.6E-24 T 31-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 SUPERFAMILY SSF64484 4 1113 0.0 T 31-10-2018 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Gene3D G3DSA:3.90.1110.10 172 331 4.6E-61 T 31-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Gene3D G3DSA:2.40.50.150 678 867 1.5E-146 T 31-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Pfam PF04567 RNA polymerase Rpb2, domain 5 600 633 2.7E-9 T 31-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Gene3D G3DSA:3.90.1800.10 1005 1113 2.0E-42 T 31-10-2018 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Pfam PF04560 RNA polymerase Rpb2, domain 7 1020 1110 5.3E-31 T 31-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Gene3D G3DSA:3.90.1070.20 476 567 3.1E-32 T 31-10-2018 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Gene3D G3DSA:2.40.270.10 648 1004 1.5E-146 T 31-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Pfam PF00562 RNA polymerase Rpb2, domain 6 648 1018 3.4E-129 T 31-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Pfam PF04566 RNA polymerase Rpb2, domain 4 516 579 1.2E-20 T 31-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06245 58a1a5715b35645e79d9cd69425e92aa 1123 Pfam PF04561 RNA polymerase Rpb2, domain 2 165 341 1.5E-39 T 31-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_05955 a2fbf772b5da91d0c1125b5ecdb34bd8 264 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 6.1E-7 T 31-10-2018 DFR86_05955 a2fbf772b5da91d0c1125b5ecdb34bd8 264 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 34 53 6.1E-7 T 31-10-2018 DFR86_05955 a2fbf772b5da91d0c1125b5ecdb34bd8 264 Gene3D G3DSA:3.50.50.60 6 264 2.2E-95 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05955 a2fbf772b5da91d0c1125b5ecdb34bd8 264 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 33 55 1.4E-5 T 31-10-2018 DFR86_05955 a2fbf772b5da91d0c1125b5ecdb34bd8 264 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 181 1.4E-5 T 31-10-2018 DFR86_05955 a2fbf772b5da91d0c1125b5ecdb34bd8 264 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 11 261 6.4E-104 T 31-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family DFR86_05955 a2fbf772b5da91d0c1125b5ecdb34bd8 264 SUPERFAMILY SSF51905 6 259 5.46E-46 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05955 a2fbf772b5da91d0c1125b5ecdb34bd8 264 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 9 262 42.163 T 31-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic DFR86_05955 a2fbf772b5da91d0c1125b5ecdb34bd8 264 Pfam PF01946 Thi4 family 15 243 1.1E-82 T 31-10-2018 DFR86_07415 2b7745524d98ef3bc69d95feb2075659 654 SUPERFAMILY SSF56112 344 625 9.71E-42 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR86_07415 2b7745524d98ef3bc69d95feb2075659 654 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 249 319 5.2E-7 T 31-10-2018 DFR86_07415 2b7745524d98ef3bc69d95feb2075659 654 SUPERFAMILY SSF48452 207 296 1.23E-6 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_07415 2b7745524d98ef3bc69d95feb2075659 654 Gene3D G3DSA:1.10.510.10 349 631 1.9E-38 T 31-10-2018 DFR86_07415 2b7745524d98ef3bc69d95feb2075659 654 SMART SM00220 360 644 1.5E-17 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR86_07415 2b7745524d98ef3bc69d95feb2075659 654 Pfam PF00069 Protein kinase domain 360 623 1.8E-28 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR86_07415 2b7745524d98ef3bc69d95feb2075659 654 Gene3D G3DSA:1.25.40.10 219 308 8.1E-6 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_07415 2b7745524d98ef3bc69d95feb2075659 654 Gene3D G3DSA:1.25.40.10 110 218 1.1E-5 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR86_07415 2b7745524d98ef3bc69d95feb2075659 654 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 366 387 - T 31-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 DFR86_07415 2b7745524d98ef3bc69d95feb2075659 654 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 488 500 - T 31-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DFR86_00330 b41e46a9a5eaa5ce7a002d7c9e257aee 217 Gene3D G3DSA:1.10.3480.10 7 215 2.1E-25 T 31-10-2018 DFR86_00330 b41e46a9a5eaa5ce7a002d7c9e257aee 217 Pfam PF02613 Nitrate reductase delta subunit 55 184 1.1E-15 T 31-10-2018 IPR020945 DMSO/Nitrate reductase chaperone DFR86_00330 b41e46a9a5eaa5ce7a002d7c9e257aee 217 SUPERFAMILY SSF89155 8 216 1.83E-32 T 31-10-2018 IPR036411 TorD-like superfamily DFR86_03600 ea4837f15f46c7ddff668c0bd4b4555f 371 Gene3D G3DSA:3.40.630.10 5 355 9.1E-84 T 31-10-2018 DFR86_03600 ea4837f15f46c7ddff668c0bd4b4555f 371 SUPERFAMILY SSF53187 4 366 6.54E-52 T 31-10-2018 DFR86_03600 ea4837f15f46c7ddff668c0bd4b4555f 371 Gene3D G3DSA:3.30.70.360 169 296 9.1E-84 T 31-10-2018 DFR86_03600 ea4837f15f46c7ddff668c0bd4b4555f 371 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 62 71 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 DFR86_03600 ea4837f15f46c7ddff668c0bd4b4555f 371 SUPERFAMILY SSF55031 168 288 1.94E-17 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain DFR86_03600 ea4837f15f46c7ddff668c0bd4b4555f 371 Pfam PF07687 Peptidase dimerisation domain 165 285 3.0E-18 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR86_03600 ea4837f15f46c7ddff668c0bd4b4555f 371 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 5 286 2.5E-73 T 31-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase DFR86_03600 ea4837f15f46c7ddff668c0bd4b4555f 371 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 96 135 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 DFR86_03600 ea4837f15f46c7ddff668c0bd4b4555f 371 Pfam PF01546 Peptidase family M20/M25/M40 63 362 5.5E-35 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR86_00585 d18aeaa526ea3592f0cfd6e757f642ee 387 SUPERFAMILY SSF53901 232 384 1.7E-28 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_00585 d18aeaa526ea3592f0cfd6e757f642ee 387 SUPERFAMILY SSF53901 5 230 1.63E-43 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_00585 d18aeaa526ea3592f0cfd6e757f642ee 387 Pfam PF02803 Thiolase, C-terminal domain 262 357 1.0E-6 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 DFR86_00585 d18aeaa526ea3592f0cfd6e757f642ee 387 Pfam PF00108 Thiolase, N-terminal domain 13 188 2.8E-19 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR86_00585 d18aeaa526ea3592f0cfd6e757f642ee 387 PIRSF PIRSF000429 1 387 2.1E-61 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR86_00585 d18aeaa526ea3592f0cfd6e757f642ee 387 Gene3D G3DSA:3.40.47.10 2 386 2.5E-116 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_04015 97b202083e9a861441597c335814ece4 111 PRINTS PR00162 Rieske 2Fe-2S subunit signature 70 82 4.4E-5 T 31-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DFR86_04015 97b202083e9a861441597c335814ece4 111 PRINTS PR00162 Rieske 2Fe-2S subunit signature 47 58 4.4E-5 T 31-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DFR86_04015 97b202083e9a861441597c335814ece4 111 PRINTS PR00162 Rieske 2Fe-2S subunit signature 83 95 4.4E-5 T 31-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DFR86_04015 97b202083e9a861441597c335814ece4 111 Gene3D G3DSA:2.102.10.10 2 111 6.9E-25 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_04015 97b202083e9a861441597c335814ece4 111 SUPERFAMILY SSF50022 12 109 2.62E-24 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_04015 97b202083e9a861441597c335814ece4 111 Pfam PF00355 Rieske [2Fe-2S] domain 11 98 6.0E-19 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 Pfam PF00118 TCP-1/cpn60 chaperonin family 29 520 4.3E-156 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 369 391 7.2E-31 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 53 71 7.2E-31 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 403 415 7.2E-31 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 83 102 7.2E-31 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 31 47 7.2E-31 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 34 46 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 83 91 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 Gene3D G3DSA:3.30.260.10 140 400 7.4E-176 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 SUPERFAMILY SSF52029 209 374 6.49E-52 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 4 519 4.0E-204 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 55 71 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 SUPERFAMILY SSF54849 140 399 1.16E-21 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 SUPERFAMILY SSF48592 11 520 1.83E-80 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 Gene3D G3DSA:3.50.7.10 213 364 7.4E-176 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR86_04955 4ec4bc1960d9063b438d578436b1cf63 549 Gene3D G3DSA:1.10.560.10 22 515 7.4E-176 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 2 237 37.683 T 31-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 Gene3D G3DSA:2.40.50.740 117 170 5.0E-21 T 31-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 Pfam PF00900 Ribosomal family S4e 91 167 1.7E-21 T 31-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 SUPERFAMILY SSF55174 47 91 8.11E-5 T 31-10-2018 DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 Gene3D G3DSA:3.10.290.40 1 112 1.6E-32 T 31-10-2018 DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 Pfam PF08071 RS4NT (NUC023) domain 3 33 2.9E-5 T 31-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 82 168 9.0E-23 T 31-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 SMART SM00363 37 101 0.0023 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 Gene3D G3DSA:2.30.30.30 174 238 2.7E-12 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 Pfam PF01479 S4 domain 46 85 1.2E-8 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06830 387ee4ec5b6e85d3e8cd677e9a432bb5 238 PIRSF PIRSF002116 1 238 1.4E-80 T 31-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09535 e85bbd128b65e1df178d5653609b730e 346 SUPERFAMILY SSF47648 1 69 1.57E-17 T 31-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR86_09535 e85bbd128b65e1df178d5653609b730e 346 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 318 3.5E-101 T 31-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 DFR86_09535 e85bbd128b65e1df178d5653609b730e 346 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 342 33.302 T 31-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 DFR86_09535 e85bbd128b65e1df178d5653609b730e 346 Gene3D G3DSA:3.40.1030.10 72 314 1.3E-113 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR86_09535 e85bbd128b65e1df178d5653609b730e 346 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 7.4E-17 T 31-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR86_09535 e85bbd128b65e1df178d5653609b730e 346 Pfam PF00591 Glycosyl transferase family, a/b domain 73 317 1.5E-72 T 31-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR86_09535 e85bbd128b65e1df178d5653609b730e 346 Gene3D G3DSA:1.20.970.10 7 181 1.3E-113 T 31-10-2018 DFR86_09535 e85bbd128b65e1df178d5653609b730e 346 SUPERFAMILY SSF52418 72 333 8.11E-76 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR86_05095 9ca48793a5685cbc3c9587f67897d375 292 SUPERFAMILY SSF159672 7 194 7.45E-16 T 31-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 SUPERFAMILY SSF51735 2 157 4.68E-46 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 SMART SM00846 2 139 5.1E-15 T 31-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 145 295 1.0E-22 T 31-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 112 3.9E-10 T 31-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 Gene3D G3DSA:3.40.50.720 4 327 1.8E-144 T 31-10-2018 DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 Gene3D G3DSA:3.30.360.10 137 333 1.8E-144 T 31-10-2018 DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 340 179.228 T 31-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 4 334 4.6E-165 T 31-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 137 144 - T 31-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 PIRSF PIRSF000149 1 320 1.3E-79 T 31-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR86_09320 75cf58d381a1e706d4a6ce6e9dde4638 340 SUPERFAMILY SSF55347 139 300 7.03E-56 T 31-10-2018 DFR86_00605 ce6e2690f499e1b6726229f83879d1a9 341 SUPERFAMILY SSF47240 8 251 4.06E-35 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR86_00605 ce6e2690f499e1b6726229f83879d1a9 341 Gene3D G3DSA:1.10.620.20 20 252 6.0E-14 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR86_06635 b734390ac5ec6da300b237a2de2c28ad 218 Gene3D G3DSA:1.10.8.100 114 188 7.8E-24 T 31-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 DFR86_06635 b734390ac5ec6da300b237a2de2c28ad 218 Pfam PF00398 Ribosomal RNA adenine dimethylase 3 209 2.2E-11 T 31-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm DFR86_06635 b734390ac5ec6da300b237a2de2c28ad 218 Gene3D G3DSA:3.40.50.150 5 159 7.8E-24 T 31-10-2018 DFR86_06635 b734390ac5ec6da300b237a2de2c28ad 218 SUPERFAMILY SSF53335 5 183 1.95E-22 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_06635 b734390ac5ec6da300b237a2de2c28ad 218 SMART SM00650 13 159 9.4E-14 T 31-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 DFR86_08270 a57fafb1e90aa62ac1e34ef354519fd1 318 PIRSF PIRSF000105 1 314 7.3E-70 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 DFR86_08270 a57fafb1e90aa62ac1e34ef354519fd1 318 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 184 208 - T 31-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_08270 a57fafb1e90aa62ac1e34ef354519fd1 318 Gene3D G3DSA:3.40.50.720 1 188 1.1E-54 T 31-10-2018 DFR86_08270 a57fafb1e90aa62ac1e34ef354519fd1 318 SUPERFAMILY SSF51735 1 184 5.08E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_08270 a57fafb1e90aa62ac1e34ef354519fd1 318 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 271 2.6E-18 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_08270 a57fafb1e90aa62ac1e34ef354519fd1 318 Gene3D G3DSA:1.10.1040.10 189 313 1.6E-35 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR86_08270 a57fafb1e90aa62ac1e34ef354519fd1 318 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 182 1.3E-52 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_08270 a57fafb1e90aa62ac1e34ef354519fd1 318 SUPERFAMILY SSF48179 187 260 7.06E-14 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_06545 dbcc7776a149062141d93c93d1d404ae 172 SMART SM00359 93 167 2.3E-4 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR86_06545 dbcc7776a149062141d93c93d1d404ae 172 Gene3D G3DSA:3.10.450.90 11 88 9.8E-11 T 31-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 DFR86_06545 dbcc7776a149062141d93c93d1d404ae 172 SUPERFAMILY SSF88802 9 89 6.54E-11 T 31-10-2018 DFR86_06545 dbcc7776a149062141d93c93d1d404ae 172 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 18 90 1.7E-16 T 31-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 DFR86_06545 dbcc7776a149062141d93c93d1d404ae 172 Pfam PF01472 PUA domain 94 163 2.0E-10 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR86_06545 dbcc7776a149062141d93c93d1d404ae 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 67 163 1.6E-8 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 DFR86_06545 dbcc7776a149062141d93c93d1d404ae 172 Gene3D G3DSA:2.30.130.10 91 167 5.1E-22 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 DFR86_06545 dbcc7776a149062141d93c93d1d404ae 172 SUPERFAMILY SSF88697 93 165 8.84E-13 T 31-10-2018 IPR015947 PUA-like superfamily DFR86_00565 888113ab2b7eab79b74a1879dae2fca7 510 Gene3D G3DSA:3.40.50.12780 17 408 9.2E-91 T 31-10-2018 DFR86_00565 888113ab2b7eab79b74a1879dae2fca7 510 Pfam PF00501 AMP-binding enzyme 34 414 1.7E-76 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR86_00565 888113ab2b7eab79b74a1879dae2fca7 510 SUPERFAMILY SSF56801 33 508 1.01E-124 T 31-10-2018 DFR86_00565 888113ab2b7eab79b74a1879dae2fca7 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR86_00565 888113ab2b7eab79b74a1879dae2fca7 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 500 2.1E-20 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR86_00565 888113ab2b7eab79b74a1879dae2fca7 510 Gene3D G3DSA:3.30.300.30 409 510 1.2E-24 T 31-10-2018 DFR86_10675 3ed14362db42f9356348e4f5dfe94e0a 455 SMART SM00887 54 403 2.9E-74 T 31-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 DFR86_10675 3ed14362db42f9356348e4f5dfe94e0a 455 Pfam PF09459 Ethylbenzene dehydrogenase 54 402 7.9E-35 T 31-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 DFR86_10675 3ed14362db42f9356348e4f5dfe94e0a 455 TIGRFAM TIGR03154 sulfolob_CbsA: cytochrome b558/566, subunit A 12 455 1.4E-222 T 31-10-2018 IPR017572 Cytochrome b558/566, subunit A GO:0005886|GO:0016021|GO:0020037|GO:0022900 DFR86_10675 3ed14362db42f9356348e4f5dfe94e0a 455 Gene3D G3DSA:2.60.40.1190 249 415 8.4E-9 T 31-10-2018 DFR86_08805 e96aa61b37bf49c39709a91e1df2775d 260 SUPERFAMILY SSF52833 1 74 5.43E-11 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_08805 e96aa61b37bf49c39709a91e1df2775d 260 Pfam PF13192 Thioredoxin domain 1 74 2.3E-9 T 31-10-2018 IPR012336 Thioredoxin-like fold DFR86_08805 e96aa61b37bf49c39709a91e1df2775d 260 Gene3D G3DSA:3.40.30.10 1 75 1.9E-7 T 31-10-2018 DFR86_04795 d216995e73ab56e4f0e84c2a02a997e2 180 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 158 37.062 T 31-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 DFR86_04795 d216995e73ab56e4f0e84c2a02a997e2 180 Gene3D G3DSA:3.30.1060.10 1 162 2.4E-71 T 31-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 DFR86_04795 d216995e73ab56e4f0e84c2a02a997e2 180 Pfam PF01625 Peptide methionine sulfoxide reductase 4 154 7.6E-65 T 31-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 DFR86_04795 d216995e73ab56e4f0e84c2a02a997e2 180 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 146 3.0E-58 T 31-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 DFR86_04795 d216995e73ab56e4f0e84c2a02a997e2 180 SUPERFAMILY SSF55068 1 165 2.62E-74 T 31-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 DFR86_01730 1a4cfc89b5cc66b896758e385ca34a2c 117 Gene3D G3DSA:3.40.1260.10 1 117 2.2E-12 T 31-10-2018 IPR027396 DsrEFH-like DFR86_01730 1a4cfc89b5cc66b896758e385ca34a2c 117 SUPERFAMILY SSF75169 1 117 3.73E-14 T 31-10-2018 IPR027396 DsrEFH-like DFR86_01730 1a4cfc89b5cc66b896758e385ca34a2c 117 Pfam PF02635 DsrE/DsrF-like family 3 117 9.3E-11 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR86_09785 3b07ed4c303c418cfa9f05275e9f3b47 218 SUPERFAMILY SSF82114 86 216 4.25E-41 T 31-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 DFR86_09785 3b07ed4c303c418cfa9f05275e9f3b47 218 Hamap MF_01285 Riboflavin kinase [ribK]. 88 216 27.88 T 31-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 DFR86_09785 3b07ed4c303c418cfa9f05275e9f3b47 218 SMART SM00419 9 62 0.0099 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 DFR86_09785 3b07ed4c303c418cfa9f05275e9f3b47 218 Pfam PF01982 Domain of unknown function DUF120 94 215 6.1E-40 T 31-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 DFR86_09785 3b07ed4c303c418cfa9f05275e9f3b47 218 SUPERFAMILY SSF46785 11 82 9.32E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_09785 3b07ed4c303c418cfa9f05275e9f3b47 218 Gene3D G3DSA:1.10.10.10 3 82 3.4E-15 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_09785 3b07ed4c303c418cfa9f05275e9f3b47 218 Gene3D G3DSA:2.40.30.30 84 218 4.5E-43 T 31-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 DFR86_09785 3b07ed4c303c418cfa9f05275e9f3b47 218 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 50 2.8E-7 T 31-10-2018 DFR86_11305 0219a40f200ec8e5a9874f57343d3ec6 150 Gene3D G3DSA:3.10.129.10 1 143 1.1E-37 T 31-10-2018 DFR86_11305 0219a40f200ec8e5a9874f57343d3ec6 150 Pfam PF01575 MaoC like domain 7 114 3.7E-16 T 31-10-2018 IPR002539 MaoC-like dehydratase domain DFR86_11305 0219a40f200ec8e5a9874f57343d3ec6 150 SUPERFAMILY SSF54637 1 140 2.34E-30 T 31-10-2018 IPR029069 HotDog domain superfamily DFR86_04270 f1e2c7327ca7967f0efbe9989af5b324 345 Pfam PF01979 Amidohydrolase family 3 273 2.9E-7 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_04270 f1e2c7327ca7967f0efbe9989af5b324 345 Gene3D G3DSA:3.20.20.140 7 288 1.3E-71 T 31-10-2018 DFR86_04270 f1e2c7327ca7967f0efbe9989af5b324 345 SUPERFAMILY SSF51556 7 290 5.45E-60 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_04270 f1e2c7327ca7967f0efbe9989af5b324 345 Gene3D G3DSA:2.30.40.10 4 325 1.3E-71 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_10950 275ce197388fd9de61c77bb6245830bf 213 Gene3D G3DSA:3.20.20.140 15 157 1.1E-7 T 31-10-2018 DFR86_10950 275ce197388fd9de61c77bb6245830bf 213 SUPERFAMILY SSF51556 16 125 1.63E-7 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_06280 7adedab3d030bdc32902499554db503f 216 SUPERFAMILY SSF53271 4 216 1.48E-59 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR86_06280 7adedab3d030bdc32902499554db503f 216 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 6 216 6.5E-64 T 31-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 DFR86_06280 7adedab3d030bdc32902499554db503f 216 Pfam PF14681 Uracil phosphoribosyltransferase 6 216 1.1E-49 T 31-10-2018 DFR86_06280 7adedab3d030bdc32902499554db503f 216 Gene3D G3DSA:3.40.50.2020 3 216 3.0E-63 T 31-10-2018 DFR86_06280 7adedab3d030bdc32902499554db503f 216 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 1 216 41.62 T 31-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 DFR86_10175 37384cf1572167c6895b577f47795518 94 Gene3D G3DSA:1.10.10.10 3 93 6.4E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10175 37384cf1572167c6895b577f47795518 94 Pfam PF14947 Winged helix-turn-helix 4 78 2.6E-22 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain DFR86_10175 37384cf1572167c6895b577f47795518 94 SUPERFAMILY SSF46785 5 79 3.69E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_06870 55005ea8a27eadfad6ea4e96175b39d2 214 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 6 206 46.039 T 31-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06870 55005ea8a27eadfad6ea4e96175b39d2 214 Gene3D G3DSA:3.30.230.10 117 213 4.8E-34 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR86_06870 55005ea8a27eadfad6ea4e96175b39d2 214 Pfam PF00333 Ribosomal protein S5, N-terminal domain 54 118 1.5E-23 T 31-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 DFR86_06870 55005ea8a27eadfad6ea4e96175b39d2 214 SUPERFAMILY SSF54768 48 119 1.36E-19 T 31-10-2018 DFR86_06870 55005ea8a27eadfad6ea4e96175b39d2 214 Pfam PF03719 Ribosomal protein S5, C-terminal domain 140 207 2.4E-21 T 31-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 DFR86_06870 55005ea8a27eadfad6ea4e96175b39d2 214 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 9 213 6.2E-94 T 31-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06870 55005ea8a27eadfad6ea4e96175b39d2 214 SUPERFAMILY SSF54211 132 211 1.59E-20 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_06870 55005ea8a27eadfad6ea4e96175b39d2 214 ProSitePatterns PS00585 Ribosomal protein S5 signature. 71 103 - T 31-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site DFR86_06870 55005ea8a27eadfad6ea4e96175b39d2 214 Gene3D G3DSA:3.30.160.770 12 116 3.6E-38 T 31-10-2018 DFR86_02815 487c4a178f4b6ab483754962339ac6e0 207 Gene3D G3DSA:1.10.150.240 18 79 1.6E-35 T 31-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 DFR86_02815 487c4a178f4b6ab483754962339ac6e0 207 Gene3D G3DSA:3.40.50.1000 5 180 1.6E-35 T 31-10-2018 IPR023214 HAD superfamily DFR86_02815 487c4a178f4b6ab483754962339ac6e0 207 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 175 1.5E-26 T 31-10-2018 DFR86_02815 487c4a178f4b6ab483754962339ac6e0 207 SUPERFAMILY SSF56784 1 178 2.59E-39 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_02815 487c4a178f4b6ab483754962339ac6e0 207 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 67 175 8.0E-8 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR86_02815 487c4a178f4b6ab483754962339ac6e0 207 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 62 169 2.9E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR86_07445 f615da17c91fc877069b21311277c51a 127 Pfam PF00571 CBS domain 75 122 4.1E-8 T 31-10-2018 IPR000644 CBS domain DFR86_07445 f615da17c91fc877069b21311277c51a 127 Pfam PF00571 CBS domain 4 58 5.2E-12 T 31-10-2018 IPR000644 CBS domain DFR86_07445 f615da17c91fc877069b21311277c51a 127 Gene3D G3DSA:3.10.580.10 1 127 8.0E-34 T 31-10-2018 DFR86_07445 f615da17c91fc877069b21311277c51a 127 SMART SM00116 11 58 5.4E-9 T 31-10-2018 IPR000644 CBS domain DFR86_07445 f615da17c91fc877069b21311277c51a 127 SMART SM00116 75 123 4.1E-8 T 31-10-2018 IPR000644 CBS domain DFR86_07445 f615da17c91fc877069b21311277c51a 127 SUPERFAMILY SSF54631 2 123 3.03E-31 T 31-10-2018 DFR86_00610 2696b3bcc9a325a64e9a99084cc67096 349 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 185 5.3E-58 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_00610 2696b3bcc9a325a64e9a99084cc67096 349 SUPERFAMILY SSF51735 5 184 4.68E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_00610 2696b3bcc9a325a64e9a99084cc67096 349 PIRSF PIRSF000105 295 345 0.0017 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 DFR86_00610 2696b3bcc9a325a64e9a99084cc67096 349 PIRSF PIRSF000105 1 302 6.9E-83 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 DFR86_00610 2696b3bcc9a325a64e9a99084cc67096 349 SUPERFAMILY SSF48179 302 338 2.89E-5 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_00610 2696b3bcc9a325a64e9a99084cc67096 349 Gene3D G3DSA:1.10.1040.10 298 344 3.6E-9 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR86_00610 2696b3bcc9a325a64e9a99084cc67096 349 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 279 3.3E-22 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_00610 2696b3bcc9a325a64e9a99084cc67096 349 SUPERFAMILY SSF48179 188 286 6.72E-21 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_00610 2696b3bcc9a325a64e9a99084cc67096 349 Gene3D G3DSA:1.10.1040.10 190 297 1.5E-23 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR86_00610 2696b3bcc9a325a64e9a99084cc67096 349 Gene3D G3DSA:3.40.50.720 1 189 7.8E-58 T 31-10-2018 DFR86_00325 4329d3c725fab58ab68b4812168fa12a 295 SUPERFAMILY SSF54862 26 230 1.88E-55 T 31-10-2018 DFR86_00325 4329d3c725fab58ab68b4812168fa12a 295 Pfam PF13247 4Fe-4S dicluster domain 92 189 2.7E-19 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_00325 4329d3c725fab58ab68b4812168fa12a 295 Gene3D G3DSA:3.30.70.20 24 60 1.1E-5 T 31-10-2018 DFR86_00325 4329d3c725fab58ab68b4812168fa12a 295 Gene3D G3DSA:3.30.70.20 75 279 9.9E-46 T 31-10-2018 DFR86_02540 e861dca92e52d01fc6889639638f8994 237 Gene3D G3DSA:3.40.630.50 2 150 3.5E-34 T 31-10-2018 DFR86_02540 e861dca92e52d01fc6889639638f8994 237 SUPERFAMILY SSF142535 4 234 6.54E-59 T 31-10-2018 DFR86_02540 e861dca92e52d01fc6889639638f8994 237 Pfam PF04414 D-aminoacyl-tRNA deacylase 37 234 4.7E-52 T 31-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 DFR86_02540 e861dca92e52d01fc6889639638f8994 237 Gene3D G3DSA:3.40.50.10700 155 236 4.5E-12 T 31-10-2018 DFR86_02540 e861dca92e52d01fc6889639638f8994 237 PIRSF PIRSF016210 1 237 1.0E-57 T 31-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 DFR86_11365 2db1201ddc14c77f74e7ef193b2696ef 437 SUPERFAMILY SSF53383 23 435 4.18E-110 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_11365 2db1201ddc14c77f74e7ef193b2696ef 437 Gene3D G3DSA:3.40.640.10 65 343 9.2E-147 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_11365 2db1201ddc14c77f74e7ef193b2696ef 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 260 297 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_11365 2db1201ddc14c77f74e7ef193b2696ef 437 Gene3D G3DSA:3.90.1150.10 28 430 9.2E-147 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_11365 2db1201ddc14c77f74e7ef193b2696ef 437 PIRSF PIRSF000521 3 436 4.0E-46 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_11365 2db1201ddc14c77f74e7ef193b2696ef 437 Pfam PF00202 Aminotransferase class-III 26 433 1.6E-101 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_05295 2a4335a646b031cb8606a17902de4d64 207 Pfam PF07849 Protein of unknown function (DUF1641) 167 203 9.9E-15 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 DFR86_02365 400baa22b7d9329e2e9cf3002b03bbf9 82 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 2.1E-12 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_02365 400baa22b7d9329e2e9cf3002b03bbf9 82 Gene3D G3DSA:1.10.10.10 3 81 2.7E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_02365 400baa22b7d9329e2e9cf3002b03bbf9 82 SUPERFAMILY SSF46785 2 79 4.55E-21 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_02365 400baa22b7d9329e2e9cf3002b03bbf9 82 SMART SM00418 12 76 2.9E-5 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_03450 f18d0fec53eb2adf04596e15865ae0bd 266 SUPERFAMILY SSF52540 2 178 1.1E-13 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03450 f18d0fec53eb2adf04596e15865ae0bd 266 Gene3D G3DSA:3.40.50.300 11 258 7.1E-15 T 31-10-2018 DFR86_04070 16bfa9fc68dbb10af901752bf63fefad 1041 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 9 29 1.6E-4 T 31-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal DFR86_04070 16bfa9fc68dbb10af901752bf63fefad 1041 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 58 114 3.3E-12 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_04070 16bfa9fc68dbb10af901752bf63fefad 1041 Pfam PF00384 Molybdopterin oxidoreductase 117 637 5.0E-34 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_04070 16bfa9fc68dbb10af901752bf63fefad 1041 SMART SM00926 56 114 2.9E-12 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_04070 16bfa9fc68dbb10af901752bf63fefad 1041 SUPERFAMILY SSF53706 53 653 6.02E-109 T 31-10-2018 DFR86_04070 16bfa9fc68dbb10af901752bf63fefad 1041 Pfam PF01568 Molydopterin dinucleotide binding domain 882 946 1.1E-6 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 DFR86_04070 16bfa9fc68dbb10af901752bf63fefad 1041 SUPERFAMILY SSF50692 845 996 5.88E-12 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR86_00535 819ee421c4c8c451d70bf6b0c8eab44b 402 Gene3D G3DSA:3.30.70.20 36 188 1.4E-39 T 31-10-2018 DFR86_00535 819ee421c4c8c451d70bf6b0c8eab44b 402 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 211 327 2.3E-11 T 31-10-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 DFR86_00535 819ee421c4c8c451d70bf6b0c8eab44b 402 SUPERFAMILY SSF54862 3 145 2.72E-46 T 31-10-2018 DFR86_00535 819ee421c4c8c451d70bf6b0c8eab44b 402 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 85 96 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_00535 819ee421c4c8c451d70bf6b0c8eab44b 402 Pfam PF13247 4Fe-4S dicluster domain 50 140 1.6E-20 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 SUPERFAMILY SSF56091 231 435 1.7E-49 T 31-10-2018 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 58 584 1.1E-181 T 31-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 409 435 - T 31-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 Gene3D G3DSA:1.10.3260.10 1 231 2.4E-76 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 Hamap MF_00407 DNA ligase [lig]. 1 584 31.157 T 31-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 Pfam PF04675 DNA ligase N terminus 2 184 3.0E-40 T 31-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 Pfam PF04679 ATP dependent DNA ligase C terminal region 461 568 4.3E-25 T 31-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 258 266 - T 31-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 Gene3D G3DSA:2.40.50.140 438 598 4.7E-58 T 31-10-2018 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 Gene3D G3DSA:3.30.470.30 232 437 7.4E-76 T 31-10-2018 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 SUPERFAMILY SSF117018 2 238 1.96E-65 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 Pfam PF01068 ATP dependent DNA ligase domain 235 435 2.6E-64 T 31-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 DFR86_07080 0a73d71ceece38e7a4a1be3ef5368b6c 599 SUPERFAMILY SSF50249 444 586 1.46E-44 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_02735 5e12536a1a10414fc1d485365ed96c22 472 Pfam PF14535 AMP-binding enzyme C-terminal domain 380 469 1.5E-13 T 31-10-2018 IPR028154 AMP-dependent ligase, C-terminal DFR86_02735 5e12536a1a10414fc1d485365ed96c22 472 Gene3D G3DSA:3.40.50.12780 28 369 3.6E-62 T 31-10-2018 DFR86_02735 5e12536a1a10414fc1d485365ed96c22 472 SUPERFAMILY SSF56801 83 420 1.26E-18 T 31-10-2018 DFR86_02735 5e12536a1a10414fc1d485365ed96c22 472 Gene3D G3DSA:3.30.300.30 372 471 1.4E-10 T 31-10-2018 DFR86_03735 30ff4cb558d9d4e5f63f234e077a2fab 489 Pfam PF12679 ABC-2 family transporter protein 180 488 1.6E-20 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 DFR86_03735 30ff4cb558d9d4e5f63f234e077a2fab 489 SUPERFAMILY SSF49478 67 110 6.28E-7 T 31-10-2018 DFR86_02390 8b53f39d17c4095438b18b62e8661148 245 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 188 245 1.8E-9 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_03470 f8b760112238fba714fbd29880177a24 529 PIRSF PIRSF006060 1 528 8.0E-28 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_03470 f8b760112238fba714fbd29880177a24 529 Gene3D G3DSA:1.20.1740.10 16 520 1.4E-10 T 31-10-2018 DFR86_03470 f8b760112238fba714fbd29880177a24 529 Pfam PF13520 Amino acid permease 20 494 7.0E-33 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_01700 e6555d24e5b7952aab849d7fb1cfd1d8 1335 Pfam PF09286 Pro-kumamolisin, activation domain 44 160 1.6E-11 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR86_01700 e6555d24e5b7952aab849d7fb1cfd1d8 1335 SUPERFAMILY SSF54897 43 176 1.38E-12 T 31-10-2018 DFR86_01700 e6555d24e5b7952aab849d7fb1cfd1d8 1335 Gene3D G3DSA:3.40.50.200 204 582 1.0E-89 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR86_01700 e6555d24e5b7952aab849d7fb1cfd1d8 1335 PIRSF PIRSF032623 1 1333 4.8E-291 T 31-10-2018 IPR017001 Peptidase S53, physarolisin II, archaeal-type DFR86_01700 e6555d24e5b7952aab849d7fb1cfd1d8 1335 SMART SM00944 35 166 6.2E-18 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR86_01700 e6555d24e5b7952aab849d7fb1cfd1d8 1335 SUPERFAMILY SSF52743 216 575 3.14E-63 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR86_03220 71aa3848458ac0b3451c3a69bb758687 137 SUPERFAMILY SSF100966 4 104 1.96E-25 T 31-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 DFR86_03220 71aa3848458ac0b3451c3a69bb758687 137 SMART SM00653 23 131 1.7E-46 T 31-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 DFR86_03220 71aa3848458ac0b3451c3a69bb758687 137 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 3 137 29.533 T 31-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 DFR86_03220 71aa3848458ac0b3451c3a69bb758687 137 SUPERFAMILY SSF75689 102 136 9.02E-11 T 31-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 DFR86_03220 71aa3848458ac0b3451c3a69bb758687 137 Gene3D G3DSA:3.30.70.3150 32 104 1.4E-27 T 31-10-2018 DFR86_03220 71aa3848458ac0b3451c3a69bb758687 137 Pfam PF01873 Domain found in IF2B/IF5 25 131 2.7E-32 T 31-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 DFR86_05675 20423a4fb17c191ebba13d8b51a1a008 226 SUPERFAMILY SSF56281 3 225 2.16E-30 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_05675 20423a4fb17c191ebba13d8b51a1a008 226 Pfam PF12706 Beta-lactamase superfamily domain 21 191 5.7E-19 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_05675 20423a4fb17c191ebba13d8b51a1a008 226 Gene3D G3DSA:3.60.15.10 3 226 4.6E-63 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_05675 20423a4fb17c191ebba13d8b51a1a008 226 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 226 34.088 T 31-10-2018 IPR022877 Protein of unknown funcion UPF0173 DFR86_05675 20423a4fb17c191ebba13d8b51a1a008 226 SMART SM00849 8 190 1.6E-8 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_03870 c77e83ff7abdae707bd4e7374058e021 259 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 19 253 2.3E-55 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 DFR86_03870 c77e83ff7abdae707bd4e7374058e021 259 Pfam PF02634 FdhD/NarQ family 24 252 1.6E-72 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 DFR86_03870 c77e83ff7abdae707bd4e7374058e021 259 Gene3D G3DSA:3.10.20.10 25 106 6.6E-8 T 31-10-2018 DFR86_03870 c77e83ff7abdae707bd4e7374058e021 259 Gene3D G3DSA:3.40.140.10 110 258 8.3E-50 T 31-10-2018 DFR86_03870 c77e83ff7abdae707bd4e7374058e021 259 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 1 253 31.66 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 DFR86_03870 c77e83ff7abdae707bd4e7374058e021 259 PIRSF PIRSF015626 2 257 1.2E-77 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 DFR86_03870 c77e83ff7abdae707bd4e7374058e021 259 SUPERFAMILY SSF53927 3 253 5.41E-69 T 31-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 DFR86_03365 d3fe4ba4f3b029c4d57637f145ab3da3 348 Gene3D G3DSA:3.50.50.60 2 346 5.9E-32 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03365 d3fe4ba4f3b029c4d57637f145ab3da3 348 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 38 7.2E-5 T 31-10-2018 DFR86_03365 d3fe4ba4f3b029c4d57637f145ab3da3 348 SUPERFAMILY SSF51905 2 288 1.68E-14 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_06725 52fd6dd381df9c55efbaf6af434d2697 128 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 127 44.226 T 31-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 DFR86_06725 52fd6dd381df9c55efbaf6af434d2697 128 SUPERFAMILY SSF46579 8 113 8.24E-25 T 31-10-2018 DFR86_06725 52fd6dd381df9c55efbaf6af434d2697 128 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 5 113 5.7E-37 T 31-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 DFR86_06725 52fd6dd381df9c55efbaf6af434d2697 128 Gene3D G3DSA:1.10.287.370 2 116 2.3E-33 T 31-10-2018 IPR009053 Prefoldin DFR86_06725 52fd6dd381df9c55efbaf6af434d2697 128 Pfam PF01920 Prefoldin subunit 10 114 9.0E-26 T 31-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 DFR86_04995 aacdff74813209ea8fd40a905e74a630 418 SUPERFAMILY SSF53067 127 287 1.68E-31 T 31-10-2018 DFR86_04995 aacdff74813209ea8fd40a905e74a630 418 Gene3D G3DSA:3.30.420.40 1 108 6.7E-22 T 31-10-2018 DFR86_04995 aacdff74813209ea8fd40a905e74a630 418 SUPERFAMILY SSF53067 2 125 1.61E-28 T 31-10-2018 DFR86_04995 aacdff74813209ea8fd40a905e74a630 418 Pfam PF02541 Ppx/GppA phosphatase family 23 286 9.0E-40 T 31-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 DFR86_04995 aacdff74813209ea8fd40a905e74a630 418 Gene3D G3DSA:3.30.420.150 109 287 2.1E-44 T 31-10-2018 DFR86_07510 35fe689ccab1f23517984936545c417a 807 Pfam PF00330 Aconitase family (aconitate hydratase) 42 493 6.0E-160 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 ProSitePatterns PS00450 Aconitase family signature 1. 358 374 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 SUPERFAMILY SSF53732 3 557 3.14E-194 T 31-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 Pfam PF00694 Aconitase C-terminal domain 624 739 3.2E-34 T 31-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 Gene3D G3DSA:3.20.19.10 579 807 2.7E-88 T 31-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 SUPERFAMILY SSF52016 565 805 1.35E-63 T 31-10-2018 DFR86_07510 35fe689ccab1f23517984936545c417a 807 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 3 806 0.0 T 31-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 DFR86_07510 35fe689ccab1f23517984936545c417a 807 Gene3D G3DSA:1.10.1440.20 522 578 2.7E-12 T 31-10-2018 DFR86_07510 35fe689ccab1f23517984936545c417a 807 PRINTS PR00415 Aconitase family signature 173 188 4.1E-40 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 PRINTS PR00415 Aconitase family signature 424 437 4.1E-40 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 PRINTS PR00415 Aconitase family signature 159 172 4.1E-40 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 PRINTS PR00415 Aconitase family signature 235 248 4.1E-40 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 PRINTS PR00415 Aconitase family signature 325 339 4.1E-40 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 PRINTS PR00415 Aconitase family signature 362 373 4.1E-40 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 PRINTS PR00415 Aconitase family signature 110 123 4.1E-40 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 PRINTS PR00415 Aconitase family signature 134 142 4.1E-40 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 PRINTS PR00415 Aconitase family signature 249 262 4.1E-40 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 Gene3D G3DSA:3.30.499.20 1 325 2.7E-136 T 31-10-2018 DFR86_07510 35fe689ccab1f23517984936545c417a 807 Gene3D G3DSA:3.30.499.10 326 520 2.5E-79 T 31-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 DFR86_07510 35fe689ccab1f23517984936545c417a 807 ProSitePatterns PS01244 Aconitase family signature 2. 424 437 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 DFR86_01825 c908537dbaee1e908a73f1e051f3c87a 511 Pfam PF02785 Biotin carboxylase C-terminal domain 341 447 8.1E-35 T 31-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 DFR86_01825 c908537dbaee1e908a73f1e051f3c87a 511 SMART SM00878 341 447 1.4E-51 T 31-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 DFR86_01825 c908537dbaee1e908a73f1e051f3c87a 511 SUPERFAMILY SSF56059 85 355 3.36E-58 T 31-10-2018 DFR86_01825 c908537dbaee1e908a73f1e051f3c87a 511 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 155 169 - T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DFR86_01825 c908537dbaee1e908a73f1e051f3c87a 511 SUPERFAMILY SSF52440 2 113 9.35E-49 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR86_01825 c908537dbaee1e908a73f1e051f3c87a 511 SUPERFAMILY SSF51246 336 452 8.89E-39 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 DFR86_01825 c908537dbaee1e908a73f1e051f3c87a 511 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 325 1.2E-62 T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DFR86_01825 c908537dbaee1e908a73f1e051f3c87a 511 Gene3D G3DSA:3.30.470.130 1 455 1.3E-170 T 31-10-2018 DFR86_01825 c908537dbaee1e908a73f1e051f3c87a 511 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 112 1.8E-45 T 31-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 DFR86_04315 361114b0af710e4bdd6a6ae7d998fdbb 235 Pfam PF04967 HTH DNA binding domain 172 223 2.5E-15 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR86_01080 56e8f6042e92453ae4ed655eac268bce 324 Gene3D G3DSA:3.40.50.300 1 324 8.0E-98 T 31-10-2018 DFR86_01080 56e8f6042e92453ae4ed655eac268bce 324 SMART SM00382 32 245 3.2E-19 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_01080 56e8f6042e92453ae4ed655eac268bce 324 SUPERFAMILY SSF52540 3 258 3.47E-66 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01080 56e8f6042e92453ae4ed655eac268bce 324 Pfam PF00005 ABC transporter 23 188 3.6E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_01080 56e8f6042e92453ae4ed655eac268bce 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 322 1.1E-27 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_01080 56e8f6042e92453ae4ed655eac268bce 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 4.1E-19 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_08115 4befda86c70c97ef04a5362295e5ec27 326 Hamap MF_00188 Protease HtpX [htpX]. 7 322 27.941 T 31-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 DFR86_08115 4befda86c70c97ef04a5362295e5ec27 326 Gene3D G3DSA:3.30.2010.10 72 164 1.7E-19 T 31-10-2018 DFR86_08115 4befda86c70c97ef04a5362295e5ec27 326 Pfam PF01435 Peptidase family M48 84 322 4.1E-32 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DFR86_05605 bda1304ab4a34748b0d35eade800d0ee 190 Pfam PF02195 ParB-like nuclease domain 5 75 2.5E-10 T 31-10-2018 IPR003115 ParB/Sulfiredoxin DFR86_05605 bda1304ab4a34748b0d35eade800d0ee 190 SMART SM00470 3 85 5.8E-14 T 31-10-2018 IPR003115 ParB/Sulfiredoxin DFR86_05605 bda1304ab4a34748b0d35eade800d0ee 190 Gene3D G3DSA:3.90.1530.10 1 91 7.6E-21 T 31-10-2018 DFR86_05605 bda1304ab4a34748b0d35eade800d0ee 190 SUPERFAMILY SSF110849 2 188 1.44E-28 T 31-10-2018 IPR036086 ParB/Sulfiredoxin superfamily DFR86_05410 78d92de443724dfc1d80bfba984529f4 313 SUPERFAMILY SSF52283 3 131 7.94E-37 T 31-10-2018 DFR86_05410 78d92de443724dfc1d80bfba984529f4 313 Gene3D G3DSA:3.40.50.720 4 309 1.7E-124 T 31-10-2018 DFR86_05410 78d92de443724dfc1d80bfba984529f4 313 Gene3D G3DSA:3.40.50.720 97 282 1.7E-124 T 31-10-2018 DFR86_05410 78d92de443724dfc1d80bfba984529f4 313 SUPERFAMILY SSF51735 100 283 1.55E-57 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_05410 78d92de443724dfc1d80bfba984529f4 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site DFR86_05410 78d92de443724dfc1d80bfba984529f4 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 311 7.2E-31 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 DFR86_05410 78d92de443724dfc1d80bfba984529f4 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 282 1.2E-62 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DFR86_04380 fdcf7a8f65d7985a8b388e337f9b99e9 278 PRINTS PR00146 Dihydrodipicolinate synthase signature 122 139 5.5E-14 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_04380 fdcf7a8f65d7985a8b388e337f9b99e9 278 PRINTS PR00146 Dihydrodipicolinate synthase signature 97 113 5.5E-14 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_04380 fdcf7a8f65d7985a8b388e337f9b99e9 278 PRINTS PR00146 Dihydrodipicolinate synthase signature 32 53 5.5E-14 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_04380 fdcf7a8f65d7985a8b388e337f9b99e9 278 PRINTS PR00146 Dihydrodipicolinate synthase signature 65 83 5.5E-14 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_04380 fdcf7a8f65d7985a8b388e337f9b99e9 278 Pfam PF00701 Dihydrodipicolinate synthetase family 3 266 1.3E-41 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_04380 fdcf7a8f65d7985a8b388e337f9b99e9 278 PIRSF PIRSF001365 1 275 1.6E-55 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_04380 fdcf7a8f65d7985a8b388e337f9b99e9 278 SUPERFAMILY SSF51569 3 265 6.32E-60 T 31-10-2018 DFR86_04380 fdcf7a8f65d7985a8b388e337f9b99e9 278 SMART SM01130 1 277 6.1E-57 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_04380 fdcf7a8f65d7985a8b388e337f9b99e9 278 Gene3D G3DSA:3.20.20.70 1 277 4.8E-81 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_04490 5d55d81fa3631e511452ed15bc9d088f 655 SUPERFAMILY SSF48208 282 644 1.62E-34 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR86_04490 5d55d81fa3631e511452ed15bc9d088f 655 Gene3D G3DSA:1.50.10.10 330 625 3.8E-21 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR86_04490 5d55d81fa3631e511452ed15bc9d088f 655 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 8 275 8.6E-12 T 31-10-2018 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR86_04490 5d55d81fa3631e511452ed15bc9d088f 655 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 309 642 1.0E-76 T 31-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR86_01290 24390d311e016561478b02c26ef00176 585 SUPERFAMILY SSF81648 235 409 2.62E-13 T 31-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 DFR86_01290 24390d311e016561478b02c26ef00176 585 SUPERFAMILY SSF81342 27 285 1.57E-45 T 31-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 DFR86_01290 24390d311e016561478b02c26ef00176 585 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 109 315 5.4E-55 T 31-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 DFR86_01290 24390d311e016561478b02c26ef00176 585 Gene3D G3DSA:1.20.810.10 21 469 1.0E-66 T 31-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 DFR86_03645 0333295f731564ca295e522664a6c43c 53 Pfam PF08394 Archaeal TRASH domain 15 51 2.4E-8 T 31-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal DFR86_03645 0333295f731564ca295e522664a6c43c 53 SMART SM00746 15 51 1.2E-8 T 31-10-2018 IPR011017 TRASH domain DFR86_00885 a5413c6fb696d23d36b6a147de66b5c9 290 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 280 2.5E-68 T 31-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 DFR86_00885 a5413c6fb696d23d36b6a147de66b5c9 290 Gene3D G3DSA:3.90.25.10 164 257 9.2E-80 T 31-10-2018 DFR86_00885 a5413c6fb696d23d36b6a147de66b5c9 290 Pfam PF04321 RmlD substrate binding domain 2 280 1.2E-64 T 31-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 DFR86_00885 a5413c6fb696d23d36b6a147de66b5c9 290 SUPERFAMILY SSF51735 2 285 2.22E-67 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_00885 a5413c6fb696d23d36b6a147de66b5c9 290 Gene3D G3DSA:3.40.50.720 4 263 9.2E-80 T 31-10-2018 DFR86_11060 01e0b2b67b72ec7d3a9a3d2d4b96a6a4 225 Gene3D G3DSA:3.30.110.40 1 79 1.8E-8 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_11060 01e0b2b67b72ec7d3a9a3d2d4b96a6a4 225 Pfam PF01206 Sulfurtransferase TusA 12 79 5.9E-10 T 31-10-2018 IPR001455 TusA-like domain DFR86_11060 01e0b2b67b72ec7d3a9a3d2d4b96a6a4 225 SUPERFAMILY SSF64307 11 79 1.07E-9 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_04290 2cfe7aa9609d3cd5b613eb669739948e 375 Pfam PF01546 Peptidase family M20/M25/M40 80 369 8.6E-36 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR86_04290 2cfe7aa9609d3cd5b613eb669739948e 375 Pfam PF07687 Peptidase dimerisation domain 175 262 1.1E-9 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR86_04290 2cfe7aa9609d3cd5b613eb669739948e 375 SUPERFAMILY SSF53187 3 369 2.54E-50 T 31-10-2018 DFR86_04290 2cfe7aa9609d3cd5b613eb669739948e 375 SUPERFAMILY SSF55031 179 291 2.69E-8 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain DFR86_04290 2cfe7aa9609d3cd5b613eb669739948e 375 Gene3D G3DSA:3.40.630.10 6 360 1.4E-66 T 31-10-2018 DFR86_04290 2cfe7aa9609d3cd5b613eb669739948e 375 Gene3D G3DSA:3.30.70.360 179 290 1.4E-66 T 31-10-2018 DFR86_04290 2cfe7aa9609d3cd5b613eb669739948e 375 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 4 363 1.8E-97 T 31-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase DFR86_03845 416a4c98c828a386fc8ff4da884b6cda 139 Pfam PF00324 Amino acid permease 12 106 6.8E-12 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR86_03845 416a4c98c828a386fc8ff4da884b6cda 139 Gene3D G3DSA:1.20.1740.10 2 128 3.4E-24 T 31-10-2018 DFR86_07320 bd7fcebfa852c0f6b671b6ac912618ce 128 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 127 30.446 T 31-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_07320 bd7fcebfa852c0f6b671b6ac912618ce 128 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 1.2E-39 T 31-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_07320 bd7fcebfa852c0f6b671b6ac912618ce 128 Pfam PF01201 Ribosomal protein S8e 4 126 6.2E-30 T 31-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 DFR86_07320 bd7fcebfa852c0f6b671b6ac912618ce 128 Gene3D G3DSA:2.40.10.310 58 128 3.0E-33 T 31-10-2018 DFR86_07320 bd7fcebfa852c0f6b671b6ac912618ce 128 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 31-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 Gene3D G3DSA:3.30.56.10 270 338 1.5E-18 T 31-10-2018 DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 Pfam PF03483 B3/4 domain 93 237 5.4E-12 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 SUPERFAMILY SSF46955 272 342 3.94E-14 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 Pfam PF03484 tRNA synthetase B5 domain 273 338 2.0E-15 T 31-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 SMART SM00874 270 338 3.4E-16 T 31-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 SUPERFAMILY SSF55681 336 537 2.49E-33 T 31-10-2018 DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 Gene3D G3DSA:3.50.40.10 74 267 2.8E-54 T 31-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 Gene3D G3DSA:3.30.56.10 3 73 8.7E-11 T 31-10-2018 DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 535 2.1E-130 T 31-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 SMART SM00873 91 250 3.6E-10 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 SUPERFAMILY SSF46955 15 70 8.79E-5 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily DFR86_05665 5d92650fa51c0a3355419705df4ac234 540 Gene3D G3DSA:3.30.930.10 357 537 2.7E-36 T 31-10-2018 DFR86_00960 eb207d4cda6c6d8261f5522dec5de980 318 SUPERFAMILY SSF53335 122 297 3.35E-43 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_00960 eb207d4cda6c6d8261f5522dec5de980 318 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 142 279 6.8E-34 T 31-10-2018 IPR006342 Methyltransferase FkbM DFR86_00960 eb207d4cda6c6d8261f5522dec5de980 318 Gene3D G3DSA:3.40.50.150 129 307 4.2E-33 T 31-10-2018 DFR86_00960 eb207d4cda6c6d8261f5522dec5de980 318 Pfam PF05050 Methyltransferase FkbM domain 144 294 1.5E-19 T 31-10-2018 IPR006342 Methyltransferase FkbM DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 SUPERFAMILY SSF51905 1 326 4.03E-45 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 Gene3D G3DSA:3.50.50.60 3 316 1.8E-94 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 4.8E-47 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 4.8E-47 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.8E-47 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 4.8E-47 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 131 140 4.8E-47 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 4.8E-47 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 4.8E-47 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 4.8E-47 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 4.8E-47 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 317 4.3E-54 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 447 1.5E-19 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PIRSF PIRSF000350 1 450 2.1E-60 T 31-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 SUPERFAMILY SSF55424 337 451 1.01E-26 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 Gene3D G3DSA:3.30.390.30 337 452 1.3E-28 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 Gene3D G3DSA:3.50.50.60 140 265 1.8E-94 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 2.1E-23 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 2.1E-23 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 128 146 2.1E-23 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.1E-23 T 31-10-2018 DFR86_01885 91d3c51812cb9c71cfb7587b57402fb0 452 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 31-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 DFR86_07675 d67448e1b4e061ff39dcc46c7464acbc 312 SUPERFAMILY SSF53639 136 303 8.63E-48 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR86_07675 d67448e1b4e061ff39dcc46c7464acbc 312 Pfam PF10120 Thiamine-phosphate synthase 148 301 1.5E-45 T 31-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DFR86_07675 d67448e1b4e061ff39dcc46c7464acbc 312 Gene3D G3DSA:3.40.225.10 132 312 3.3E-48 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR86_05700 24d396293cd5fc1dd9fc53eb40f3e437 392 Gene3D G3DSA:1.10.3210.10 1 274 5.5E-77 T 31-10-2018 DFR86_05700 24d396293cd5fc1dd9fc53eb40f3e437 392 SMART SM00471 46 173 6.0E-10 T 31-10-2018 IPR003607 HD/PDEase domain DFR86_05700 24d396293cd5fc1dd9fc53eb40f3e437 392 SUPERFAMILY SSF109604 1 390 1.14E-81 T 31-10-2018 DFR86_05700 24d396293cd5fc1dd9fc53eb40f3e437 392 Pfam PF01966 HD domain 50 164 7.8E-12 T 31-10-2018 IPR006674 HD domain DFR86_05045 e97907df2b733decfcbf2296316090a7 429 Gene3D G3DSA:3.10.20.70 7 94 5.1E-10 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_05045 e97907df2b733decfcbf2296316090a7 429 Pfam PF16952 Glutamine synthetase N-terminal domain 6 85 1.9E-10 T 31-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR86_05045 e97907df2b733decfcbf2296316090a7 429 Pfam PF00120 Glutamine synthetase, catalytic domain 104 426 8.8E-104 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_05045 e97907df2b733decfcbf2296316090a7 429 SUPERFAMILY SSF54368 3 85 8.11E-9 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_05045 e97907df2b733decfcbf2296316090a7 429 Gene3D G3DSA:3.30.590.10 106 429 2.2E-107 T 31-10-2018 DFR86_05045 e97907df2b733decfcbf2296316090a7 429 SUPERFAMILY SSF55931 104 426 1.08E-101 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR86_05045 e97907df2b733decfcbf2296316090a7 429 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 223 238 - T 31-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR86_05045 e97907df2b733decfcbf2296316090a7 429 SMART SM01230 102 347 3.5E-91 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_01630 cf014b3669eb014e1fc99890fb6c5e66 301 Gene3D G3DSA:3.40.50.720 3 226 4.0E-78 T 31-10-2018 DFR86_01630 cf014b3669eb014e1fc99890fb6c5e66 301 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 226 8.9E-42 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 DFR86_01630 cf014b3669eb014e1fc99890fb6c5e66 301 SUPERFAMILY SSF51735 3 299 1.86E-65 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_01630 cf014b3669eb014e1fc99890fb6c5e66 301 Gene3D G3DSA:3.90.25.10 165 288 4.0E-78 T 31-10-2018 DFR86_01365 955cde161dc409fc5dc03b9606d0ccca 451 Gene3D G3DSA:1.20.1250.20 15 445 4.1E-28 T 31-10-2018 DFR86_01365 955cde161dc409fc5dc03b9606d0ccca 451 SUPERFAMILY SSF103473 10 429 8.76E-30 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_01365 955cde161dc409fc5dc03b9606d0ccca 451 Pfam PF00083 Sugar (and other) transporter 45 364 7.0E-14 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR86_02145 9b75c65fddce3a89768e3dfcb7fb5322 78 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 4 73 4.0E-18 T 31-10-2018 IPR011893 Selenoprotein, Rdx-type DFR86_02145 9b75c65fddce3a89768e3dfcb7fb5322 78 SUPERFAMILY SSF52833 3 76 4.47E-18 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_02145 9b75c65fddce3a89768e3dfcb7fb5322 78 Pfam PF10262 Rdx family 3 73 6.6E-19 T 31-10-2018 IPR011893 Selenoprotein, Rdx-type DFR86_02145 9b75c65fddce3a89768e3dfcb7fb5322 78 Gene3D G3DSA:3.40.30.10 1 77 4.6E-25 T 31-10-2018 DFR86_06565 ec26c11b73f8c526e47f0f9722f524b9 170 Pfam PF02002 TFIIE alpha subunit 6 104 5.4E-23 T 31-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR86_06565 ec26c11b73f8c526e47f0f9722f524b9 170 SMART SM00531 12 150 7.3E-36 T 31-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR86_06565 ec26c11b73f8c526e47f0f9722f524b9 170 PIRSF PIRSF006373 1 168 5.1E-65 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 DFR86_06565 ec26c11b73f8c526e47f0f9722f524b9 170 Hamap MF_01909 Transcription factor E [tfe]. 1 158 26.356 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 DFR86_06565 ec26c11b73f8c526e47f0f9722f524b9 170 SUPERFAMILY SSF46785 2 81 1.21E-22 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_06565 ec26c11b73f8c526e47f0f9722f524b9 170 TIGRFAM TIGR00373 TIGR00373: transcription factor E 11 159 1.1E-44 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 DFR86_06565 ec26c11b73f8c526e47f0f9722f524b9 170 Gene3D G3DSA:1.10.10.10 1 81 5.0E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 SUPERFAMILY SSF54913 214 285 2.78E-14 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 189 285 3.9E-25 T 31-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 Gene3D G3DSA:3.40.190.10 2 195 6.0E-63 T 31-10-2018 DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 Pfam PF08029 HisG, C-terminal domain 211 283 4.3E-18 T 31-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 144 165 - T 31-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 SUPERFAMILY SSF53850 1 211 1.02E-61 T 31-10-2018 DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 184 3.0E-63 T 31-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 Pfam PF01634 ATP phosphoribosyltransferase 49 206 4.1E-48 T 31-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 Gene3D G3DSA:3.40.190.10 88 179 6.0E-63 T 31-10-2018 DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 Gene3D G3DSA:3.30.70.120 214 286 1.2E-17 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal DFR86_08520 437324035c06fc10d3de4bc5bcdaea35 286 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 286 31.162 T 31-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 DFR86_04400 c8952108ceab5bed2bcf161f0b7d8c59 953 Gene3D G3DSA:3.20.110.10 203 409 6.8E-52 T 31-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily DFR86_04400 c8952108ceab5bed2bcf161f0b7d8c59 953 SUPERFAMILY SSF88713 208 436 1.69E-59 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DFR86_04400 c8952108ceab5bed2bcf161f0b7d8c59 953 Gene3D G3DSA:2.70.98.30 611 852 1.1E-17 T 31-10-2018 DFR86_04400 c8952108ceab5bed2bcf161f0b7d8c59 953 Pfam PF09261 Alpha mannosidase middle domain 461 533 4.8E-19 T 31-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 DFR86_04400 c8952108ceab5bed2bcf161f0b7d8c59 953 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 208 446 3.4E-68 T 31-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 DFR86_04400 c8952108ceab5bed2bcf161f0b7d8c59 953 SUPERFAMILY SSF74650 556 952 2.51E-75 T 31-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 DFR86_04400 c8952108ceab5bed2bcf161f0b7d8c59 953 SMART SM00872 461 534 2.5E-21 T 31-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 DFR86_04400 c8952108ceab5bed2bcf161f0b7d8c59 953 Gene3D G3DSA:1.20.1270.50 464 555 2.3E-19 T 31-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 DFR86_04400 c8952108ceab5bed2bcf161f0b7d8c59 953 SUPERFAMILY SSF88688 460 563 7.19E-20 T 31-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily DFR86_04400 c8952108ceab5bed2bcf161f0b7d8c59 953 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 560 951 6.0E-69 T 31-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 DFR86_04965 71071675cd0b98c5cfb1160a17aa080a 217 SUPERFAMILY SSF117396 1 216 1.05E-55 T 31-10-2018 IPR036520 UPF0759 superfamily DFR86_04965 71071675cd0b98c5cfb1160a17aa080a 217 Pfam PF01904 Protein of unknown function DUF72 16 203 1.3E-33 T 31-10-2018 IPR002763 Protein of unknown function DUF72 DFR86_04965 71071675cd0b98c5cfb1160a17aa080a 217 Gene3D G3DSA:3.20.20.410 1 217 1.9E-42 T 31-10-2018 IPR036520 UPF0759 superfamily DFR86_03000 ad68f13e4c5e08032cb2790266b6a100 139 Gene3D G3DSA:3.30.530.20 11 134 2.1E-9 T 31-10-2018 IPR023393 START-like domain superfamily DFR86_03000 ad68f13e4c5e08032cb2790266b6a100 139 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 6 132 2.3E-16 T 31-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G DFR86_03000 ad68f13e4c5e08032cb2790266b6a100 139 SUPERFAMILY SSF55961 16 128 7.42E-7 T 31-10-2018 DFR86_06070 f1cd26fc6c2115051ced9d18464ba393 212 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 212 27.651 T 31-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 DFR86_06070 f1cd26fc6c2115051ced9d18464ba393 212 Pfam PF01092 Ribosomal protein S6e 115 211 1.8E-24 T 31-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06070 f1cd26fc6c2115051ced9d18464ba393 212 ProSitePatterns PS00578 Ribosomal protein S6e signature. 150 161 - T 31-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06070 f1cd26fc6c2115051ced9d18464ba393 212 SMART SM01405 107 211 3.1E-30 T 31-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_02375 a03c4154427e779712898dd67a1a0dd9 280 Pfam PF02540 NAD synthase 19 259 5.6E-75 T 31-10-2018 IPR022310 NAD/GMP synthase DFR86_02375 a03c4154427e779712898dd67a1a0dd9 280 Gene3D G3DSA:3.40.50.620 11 264 3.0E-77 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_02375 a03c4154427e779712898dd67a1a0dd9 280 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 14 262 48.769 T 31-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 DFR86_02375 a03c4154427e779712898dd67a1a0dd9 280 TIGRFAM TIGR00552 nadE: NAD+ synthetase 16 262 8.2E-73 T 31-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 DFR86_02375 a03c4154427e779712898dd67a1a0dd9 280 SUPERFAMILY SSF52402 9 259 3.7E-71 T 31-10-2018 DFR86_05335 75d7e8dacfb2b25d7b96a596edde7798 412 Pfam PF09079 CDC6, C terminal winged helix domain 316 390 2.3E-18 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR86_05335 75d7e8dacfb2b25d7b96a596edde7798 412 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 17 387 4.8E-100 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR86_05335 75d7e8dacfb2b25d7b96a596edde7798 412 SUPERFAMILY SSF52540 17 292 2.4E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_05335 75d7e8dacfb2b25d7b96a596edde7798 412 Gene3D G3DSA:3.40.50.300 33 214 2.3E-72 T 31-10-2018 DFR86_05335 75d7e8dacfb2b25d7b96a596edde7798 412 Gene3D G3DSA:1.10.8.60 17 295 2.3E-72 T 31-10-2018 DFR86_05335 75d7e8dacfb2b25d7b96a596edde7798 412 Hamap MF_01407 ORC1-type DNA replication protein. 10 398 25.118 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR86_05335 75d7e8dacfb2b25d7b96a596edde7798 412 SMART SM01074 315 399 7.5E-24 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR86_05335 75d7e8dacfb2b25d7b96a596edde7798 412 Gene3D G3DSA:1.10.10.10 301 409 3.6E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_05335 75d7e8dacfb2b25d7b96a596edde7798 412 Pfam PF13401 AAA domain 61 174 5.7E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_05335 75d7e8dacfb2b25d7b96a596edde7798 412 SUPERFAMILY SSF46785 302 405 1.36E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_09185 0f2dbd0604ff07d2003cdf97c80b35e9 332 SUPERFAMILY SSF51998 1 331 3.75E-58 T 31-10-2018 DFR86_09185 0f2dbd0604ff07d2003cdf97c80b35e9 332 Gene3D G3DSA:3.20.70.20 3 332 3.6E-42 T 31-10-2018 DFR86_09185 0f2dbd0604ff07d2003cdf97c80b35e9 332 PIRSF PIRSF027893 1 331 4.8E-112 T 31-10-2018 IPR014537 Uncharacterised conserved protein UCP027893 DFR86_09185 0f2dbd0604ff07d2003cdf97c80b35e9 332 Pfam PF05167 Uncharacterised ACR (DUF711) 165 316 1.3E-27 T 31-10-2018 IPR007841 Uncharacterised protein family UPF0210 DFR86_00095 98913f9acd9c9530900961cac5ba8966 420 Pfam PF00753 Metallo-beta-lactamase superfamily 20 205 2.7E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_00095 98913f9acd9c9530900961cac5ba8966 420 SUPERFAMILY SSF56281 9 404 4.25E-31 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_00095 98913f9acd9c9530900961cac5ba8966 420 Gene3D G3DSA:3.40.50.10710 218 378 1.3E-50 T 31-10-2018 DFR86_00095 98913f9acd9c9530900961cac5ba8966 420 Gene3D G3DSA:3.60.15.10 10 408 1.3E-50 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_00095 98913f9acd9c9530900961cac5ba8966 420 SMART SM00849 21 211 0.0026 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_00365 51fd70c70b244102949fe5420b620dbc 293 SUPERFAMILY SSF161098 13 283 3.46E-44 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_00365 51fd70c70b244102949fe5420b620dbc 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 283 3.2E-14 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_00365 51fd70c70b244102949fe5420b620dbc 293 Gene3D G3DSA:1.10.3720.10 6 279 2.0E-47 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_00750 5faf851fadcc0095eedf2464d82405f6 448 Gene3D G3DSA:3.40.190.10 164 400 4.8E-44 T 31-10-2018 DFR86_00750 5faf851fadcc0095eedf2464d82405f6 448 Pfam PF01547 Bacterial extracellular solute-binding protein 54 340 7.1E-26 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein DFR86_00750 5faf851fadcc0095eedf2464d82405f6 448 SUPERFAMILY SSF53850 44 408 1.81E-50 T 31-10-2018 DFR86_00750 5faf851fadcc0095eedf2464d82405f6 448 Gene3D G3DSA:3.40.190.10 64 385 4.8E-44 T 31-10-2018 DFR86_05705 3500e29b70fc8af354b58f942f79b6c6 226 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 189 8.9E-16 T 31-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 DFR86_05705 3500e29b70fc8af354b58f942f79b6c6 226 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 97 4.2E-14 T 31-10-2018 DFR86_05705 3500e29b70fc8af354b58f942f79b6c6 226 Pfam PF08282 haloacid dehalogenase-like hydrolase 117 214 6.1E-17 T 31-10-2018 DFR86_05705 3500e29b70fc8af354b58f942f79b6c6 226 SUPERFAMILY SSF56784 2 214 1.13E-43 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_05705 3500e29b70fc8af354b58f942f79b6c6 226 Hamap MF_01419 Phosphoglycolate phosphatase. 2 221 26.766 T 31-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 DFR86_05705 3500e29b70fc8af354b58f942f79b6c6 226 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 2 215 1.7E-69 T 31-10-2018 DFR86_05705 3500e29b70fc8af354b58f942f79b6c6 226 Gene3D G3DSA:3.90.1070.10 80 142 2.5E-60 T 31-10-2018 DFR86_05705 3500e29b70fc8af354b58f942f79b6c6 226 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 5 220 9.5E-33 T 31-10-2018 DFR86_05705 3500e29b70fc8af354b58f942f79b6c6 226 Gene3D G3DSA:3.40.50.1000 5 205 2.5E-60 T 31-10-2018 IPR023214 HAD superfamily DFR86_09510 93096b962471850232c739710f79c423 395 SUPERFAMILY SSF53383 25 392 2.5E-102 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_09510 93096b962471850232c739710f79c423 395 Pfam PF00155 Aminotransferase class I and II 33 384 2.0E-69 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR86_09510 93096b962471850232c739710f79c423 395 Gene3D G3DSA:3.90.1150.10 28 387 1.5E-111 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_09510 93096b962471850232c739710f79c423 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 DFR86_09510 93096b962471850232c739710f79c423 395 Gene3D G3DSA:3.40.640.10 64 286 1.5E-111 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_07890 ba728f384397d24aaf6a479579c570f3 414 Pfam PF00534 Glycosyl transferases group 1 232 375 1.9E-19 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR86_07890 ba728f384397d24aaf6a479579c570f3 414 Gene3D G3DSA:3.40.50.2000 224 380 1.2E-27 T 31-10-2018 DFR86_07890 ba728f384397d24aaf6a479579c570f3 414 SUPERFAMILY SSF53756 80 410 5.76E-31 T 31-10-2018 DFR86_10465 4e76af10c329f8666d21181c7c67080c 237 Gene3D G3DSA:3.40.1350.10 119 229 1.4E-34 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 DFR86_10465 4e76af10c329f8666d21181c7c67080c 237 Pfam PF01939 Endonuclease NucS 26 228 4.6E-59 T 31-10-2018 IPR002793 Endonuclease NucS GO:0004519 DFR86_10465 4e76af10c329f8666d21181c7c67080c 237 Gene3D G3DSA:2.70.180.20 1 118 1.9E-31 T 31-10-2018 DFR86_10465 4e76af10c329f8666d21181c7c67080c 237 Hamap MF_00722 Endonuclease NucS [nucS]. 25 235 35.098 T 31-10-2018 IPR002793 Endonuclease NucS GO:0004519 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 68 3.5E-14 T 31-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 3 582 3.7E-301 T 31-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 589 51.655 T 31-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 SUPERFAMILY SSF52540 149 442 1.95E-76 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 SMART SM00382 225 413 0.0021 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 213 436 7.7E-84 T 31-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 SUPERFAMILY SSF47917 449 530 3.66E-20 T 31-10-2018 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 Gene3D G3DSA:2.40.50.100 116 186 2.2E-170 T 31-10-2018 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 SUPERFAMILY SSF50615 3 71 1.67E-14 T 31-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 Gene3D G3DSA:2.40.30.20 1 71 4.4E-29 T 31-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 Gene3D G3DSA:1.10.1140.10 437 591 5.2E-45 T 31-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 Gene3D G3DSA:3.40.50.300 72 436 2.2E-170 T 31-10-2018 DFR86_08655 dd8ad70dd7ae4c72594c28e9f4e8d1c8 591 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 84 204 1.5E-46 T 31-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08330 737d6ad0cdf2d7498466e9a6ca3903aa 447 Gene3D G3DSA:3.60.20.10 6 430 3.3E-132 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_08330 737d6ad0cdf2d7498466e9a6ca3903aa 447 Gene3D G3DSA:3.40.50.2020 250 414 3.3E-132 T 31-10-2018 DFR86_08330 737d6ad0cdf2d7498466e9a6ca3903aa 447 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 5 429 42.625 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 DFR86_08330 737d6ad0cdf2d7498466e9a6ca3903aa 447 Pfam PF00156 Phosphoribosyl transferase domain 256 361 1.4E-8 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR86_08330 737d6ad0cdf2d7498466e9a6ca3903aa 447 PIRSF PIRSF000485 2 445 3.0E-153 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 DFR86_08330 737d6ad0cdf2d7498466e9a6ca3903aa 447 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 6 430 1.9E-118 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 DFR86_08330 737d6ad0cdf2d7498466e9a6ca3903aa 447 SUPERFAMILY SSF53271 226 432 3.93E-62 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR86_08330 737d6ad0cdf2d7498466e9a6ca3903aa 447 Pfam PF13522 Glutamine amidotransferase domain 67 184 2.1E-12 T 31-10-2018 DFR86_08330 737d6ad0cdf2d7498466e9a6ca3903aa 447 SUPERFAMILY SSF56235 6 232 1.2E-50 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_00510 c01c8fa47f4f4067f234c43743f58613 85 Gene3D G3DSA:3.30.70.20 10 85 2.8E-16 T 31-10-2018 DFR86_00510 c01c8fa47f4f4067f234c43743f58613 85 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 10 84 9.8E-32 T 31-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 DFR86_00510 c01c8fa47f4f4067f234c43743f58613 85 Pfam PF14697 4Fe-4S dicluster domain 30 81 1.2E-10 T 31-10-2018 DFR86_00510 c01c8fa47f4f4067f234c43743f58613 85 SUPERFAMILY SSF54862 19 83 3.24E-21 T 31-10-2018 DFR86_00510 c01c8fa47f4f4067f234c43743f58613 85 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_02000 edfe1fd4ee83406afe7b4c0f6903ad56 743 SUPERFAMILY SSF52540 67 381 1.93E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_02000 edfe1fd4ee83406afe7b4c0f6903ad56 743 Pfam PF00271 Helicase conserved C-terminal domain 265 368 2.8E-17 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_02000 edfe1fd4ee83406afe7b4c0f6903ad56 743 SMART SM00490 288 369 1.1E-18 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_02000 edfe1fd4ee83406afe7b4c0f6903ad56 743 Pfam PF00270 DEAD/DEAH box helicase 58 220 8.3E-25 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_02000 edfe1fd4ee83406afe7b4c0f6903ad56 743 Pfam PF09369 Domain of unknown function (DUF1998) 629 701 9.6E-13 T 31-10-2018 IPR018973 DEAD/DEAH-box helicase, putative DFR86_02000 edfe1fd4ee83406afe7b4c0f6903ad56 743 SMART SM00487 52 249 4.7E-35 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_02000 edfe1fd4ee83406afe7b4c0f6903ad56 743 Gene3D G3DSA:3.40.50.300 34 230 5.7E-40 T 31-10-2018 DFR86_02000 edfe1fd4ee83406afe7b4c0f6903ad56 743 Gene3D G3DSA:3.40.50.300 254 410 3.4E-25 T 31-10-2018 DFR86_00875 b3661c8397d1b1358622329097231426 354 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 238 270 0.0022 T 31-10-2018 IPR001451 Hexapeptide repeat DFR86_00875 b3661c8397d1b1358622329097231426 354 Gene3D G3DSA:2.160.10.10 240 353 4.3E-20 T 31-10-2018 DFR86_00875 b3661c8397d1b1358622329097231426 354 Gene3D G3DSA:3.90.550.10 1 239 5.5E-71 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00875 b3661c8397d1b1358622329097231426 354 SUPERFAMILY SSF53448 1 309 7.98E-85 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00875 b3661c8397d1b1358622329097231426 354 Pfam PF00483 Nucleotidyl transferase 2 235 1.8E-57 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR86_00875 b3661c8397d1b1358622329097231426 354 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 332 2.6E-92 T 31-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 DFR86_00875 b3661c8397d1b1358622329097231426 354 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 354 1.4E-145 T 31-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form DFR86_00875 b3661c8397d1b1358622329097231426 354 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 271 298 7.0E-10 T 31-10-2018 IPR001451 Hexapeptide repeat DFR86_09315 cbaf0018a5c6d93f16b3ebb83eb07f42 135 SUPERFAMILY SSF52402 12 135 5.86E-23 T 31-10-2018 DFR86_09315 cbaf0018a5c6d93f16b3ebb83eb07f42 135 Gene3D G3DSA:3.40.50.620 9 135 3.8E-21 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_09315 cbaf0018a5c6d93f16b3ebb83eb07f42 135 Pfam PF00582 Universal stress protein family 12 135 3.1E-16 T 31-10-2018 IPR006016 UspA DFR86_09315 cbaf0018a5c6d93f16b3ebb83eb07f42 135 PRINTS PR01438 Universal stress protein signature 113 135 1.9E-13 T 31-10-2018 IPR006015 Universal stress protein A DFR86_09315 cbaf0018a5c6d93f16b3ebb83eb07f42 135 PRINTS PR01438 Universal stress protein signature 12 30 1.9E-13 T 31-10-2018 IPR006015 Universal stress protein A DFR86_09315 cbaf0018a5c6d93f16b3ebb83eb07f42 135 PRINTS PR01438 Universal stress protein signature 95 107 1.9E-13 T 31-10-2018 IPR006015 Universal stress protein A DFR86_10300 bd8b88521d4dbb02f9d458cfaa2a1543 482 SUPERFAMILY SSF56112 94 299 5.33E-23 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR86_10300 bd8b88521d4dbb02f9d458cfaa2a1543 482 Pfam PF03109 ABC1 family 111 209 1.5E-23 T 31-10-2018 IPR004147 UbiB domain DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 Pfam PF00288 GHMP kinases N terminal domain 77 144 1.3E-15 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 TIGRFAM TIGR00191 thrB: homoserine kinase 3 290 1.1E-66 T 31-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 84 95 - T 31-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 Gene3D G3DSA:3.30.230.10 1 163 5.5E-47 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 Hamap MF_00384 Homoserine kinase [thrB]. 5 305 27.923 T 31-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 Pfam PF08544 GHMP kinases C terminal 211 279 1.2E-6 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 Gene3D G3DSA:3.30.70.890 164 293 1.8E-27 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 PIRSF PIRSF000676 1 306 3.6E-82 T 31-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 SUPERFAMILY SSF55060 165 284 1.19E-23 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 PRINTS PR00958 Homoserine kinase signature 10 25 2.1E-24 T 31-10-2018 DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 PRINTS PR00958 Homoserine kinase signature 250 265 2.1E-24 T 31-10-2018 DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 PRINTS PR00958 Homoserine kinase signature 131 144 2.1E-24 T 31-10-2018 DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 PRINTS PR00958 Homoserine kinase signature 171 188 2.1E-24 T 31-10-2018 DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 PRINTS PR00958 Homoserine kinase signature 91 106 2.1E-24 T 31-10-2018 DFR86_03275 859bfc018e4761b48138da9ab45e8528 307 SUPERFAMILY SSF54211 1 156 7.59E-33 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_08855 9245bd4438d5e64804354776f5f8925f 345 SUPERFAMILY SSF56796 24 341 3.4E-84 T 31-10-2018 DFR86_08855 9245bd4438d5e64804354776f5f8925f 345 Gene3D G3DSA:3.40.50.1970 1 155 1.1E-46 T 31-10-2018 DFR86_08855 9245bd4438d5e64804354776f5f8925f 345 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 39 336 5.1E-106 T 31-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 DFR86_08855 9245bd4438d5e64804354776f5f8925f 345 Gene3D G3DSA:1.20.1090.10 156 344 8.7E-51 T 31-10-2018 DFR86_08855 9245bd4438d5e64804354776f5f8925f 345 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 345 55.375 T 31-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 DFR86_08855 9245bd4438d5e64804354776f5f8925f 345 PIRSF PIRSF001455 3 344 9.8E-112 T 31-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 DFR86_08855 9245bd4438d5e64804354776f5f8925f 345 Pfam PF01761 3-dehydroquinate synthase 50 311 1.1E-91 T 31-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 DFR86_06275 844b54672f2ce790162f76572a81cc1e 81 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 78 25.439 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06275 844b54672f2ce790162f76572a81cc1e 81 Pfam PF01200 Ribosomal protein S28e 17 77 3.3E-30 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06275 844b54672f2ce790162f76572a81cc1e 81 SUPERFAMILY SSF50249 15 79 1.11E-24 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_06275 844b54672f2ce790162f76572a81cc1e 81 ProSitePatterns PS00961 Ribosomal protein S28e signature. 69 77 - T 31-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06275 844b54672f2ce790162f76572a81cc1e 81 Gene3D G3DSA:2.40.50.140 11 81 1.4E-31 T 31-10-2018 DFR86_06275 844b54672f2ce790162f76572a81cc1e 81 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 19 59 3.0E-15 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 Gene3D G3DSA:3.90.740.10 198 426 6.2E-220 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 Gene3D G3DSA:3.40.50.620 6 646 6.2E-220 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 SUPERFAMILY SSF50677 211 418 6.54E-29 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 5 919 1.1E-223 T 31-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 Gene3D G3DSA:3.30.2320.20 784 918 8.4E-10 T 31-10-2018 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 9 494 8.1E-52 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 555 649 2.4E-9 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 SUPERFAMILY SSF52374 2 655 4.69E-90 T 31-10-2018 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 SUPERFAMILY SSF47323 665 770 2.99E-13 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 3 920 15.082 T 31-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 Pfam PF08264 Anticodon-binding domain of tRNA 682 807 1.0E-12 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 Gene3D G3DSA:1.10.10.720 813 864 8.4E-10 T 31-10-2018 DFR86_01400 e9b5daacbe7ab4e1d46928fd0f8eacfa 920 Gene3D G3DSA:1.10.730.10 650 760 4.6E-9 T 31-10-2018 DFR86_04255 1d623a7e4e6ff99712ab8d9ffb7bef7a 433 Gene3D G3DSA:3.20.20.140 48 405 1.1E-111 T 31-10-2018 DFR86_04255 1d623a7e4e6ff99712ab8d9ffb7bef7a 433 Pfam PF01979 Amidohydrolase family 44 418 1.5E-15 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_04255 1d623a7e4e6ff99712ab8d9ffb7bef7a 433 SUPERFAMILY SSF51556 49 369 4.17E-72 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_04255 1d623a7e4e6ff99712ab8d9ffb7bef7a 433 Gene3D G3DSA:2.30.40.10 2 428 1.1E-111 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04255 1d623a7e4e6ff99712ab8d9ffb7bef7a 433 SUPERFAMILY SSF51338 2 421 2.52E-15 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_07375 a7a06bfcfdf81197e4b729768abfeb26 365 Gene3D G3DSA:3.30.470.20 181 362 2.1E-53 T 31-10-2018 DFR86_07375 a7a06bfcfdf81197e4b729768abfeb26 365 SUPERFAMILY SSF56059 103 293 2.83E-47 T 31-10-2018 DFR86_07375 a7a06bfcfdf81197e4b729768abfeb26 365 Gene3D G3DSA:3.40.50.20 9 101 3.1E-28 T 31-10-2018 DFR86_07375 a7a06bfcfdf81197e4b729768abfeb26 365 SUPERFAMILY SSF51246 300 360 9.42E-14 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 DFR86_07375 a7a06bfcfdf81197e4b729768abfeb26 365 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 11 350 7.6E-117 T 31-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 DFR86_07375 a7a06bfcfdf81197e4b729768abfeb26 365 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 11 344 34.62 T 31-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 DFR86_07375 a7a06bfcfdf81197e4b729768abfeb26 365 Pfam PF02222 ATP-grasp domain 111 273 6.9E-45 T 31-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type DFR86_07375 a7a06bfcfdf81197e4b729768abfeb26 365 SUPERFAMILY SSF52440 9 97 8.49E-18 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR86_07375 a7a06bfcfdf81197e4b729768abfeb26 365 Gene3D G3DSA:3.30.1490.20 102 180 3.0E-19 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_03205 52b43d4c3bffd73d8a54353bbacdb7b2 208 Pfam PF01351 Ribonuclease HII 3 194 1.9E-45 T 31-10-2018 IPR024567 Ribonuclease HII/HIII domain DFR86_03205 52b43d4c3bffd73d8a54353bbacdb7b2 208 SUPERFAMILY SSF53098 3 196 1.67E-48 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily DFR86_03205 52b43d4c3bffd73d8a54353bbacdb7b2 208 Gene3D G3DSA:3.30.420.10 3 155 3.1E-37 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 DFR86_03205 52b43d4c3bffd73d8a54353bbacdb7b2 208 Gene3D G3DSA:1.10.10.460 156 201 7.0E-17 T 31-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 DFR86_03205 52b43d4c3bffd73d8a54353bbacdb7b2 208 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 3 197 2.1E-57 T 31-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 DFR86_06020 4cabbc7eb9992c3e4cda118e2afe68c6 111 ProDom PD012268 RIBOSOMAL S25 40S RIBONUCLEOPROTEIN S25 MULTIGENE FAMILY TRANSCRIPTION STRAIN DIRECT 44 105 3.0E-4 T 31-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06020 4cabbc7eb9992c3e4cda118e2afe68c6 111 SUPERFAMILY SSF46785 47 103 1.44E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_06020 4cabbc7eb9992c3e4cda118e2afe68c6 111 Gene3D G3DSA:1.10.10.10 41 111 4.1E-14 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_06020 4cabbc7eb9992c3e4cda118e2afe68c6 111 Pfam PF03297 S25 ribosomal protein 14 106 2.5E-19 T 31-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_10130 79f22b82274eb040b54b1bee592fdb74 337 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 214 238 - T 31-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_10130 79f22b82274eb040b54b1bee592fdb74 337 Pfam PF00549 CoA-ligase 221 325 9.5E-16 T 31-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_10130 79f22b82274eb040b54b1bee592fdb74 337 PIRSF PIRSF001554 1 337 6.2E-99 T 31-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR86_10130 79f22b82274eb040b54b1bee592fdb74 337 SUPERFAMILY SSF56059 1 199 1.8E-44 T 31-10-2018 DFR86_10130 79f22b82274eb040b54b1bee592fdb74 337 Gene3D G3DSA:3.30.1490.20 21 81 7.4E-50 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_10130 79f22b82274eb040b54b1bee592fdb74 337 SUPERFAMILY SSF52210 207 332 4.97E-39 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_10130 79f22b82274eb040b54b1bee592fdb74 337 Gene3D G3DSA:3.30.470.20 1 197 7.4E-50 T 31-10-2018 DFR86_10130 79f22b82274eb040b54b1bee592fdb74 337 Gene3D G3DSA:3.40.50.261 200 337 7.0E-43 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR86_10130 79f22b82274eb040b54b1bee592fdb74 337 Pfam PF08442 ATP-grasp domain 2 169 6.4E-27 T 31-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR86_04680 15163f66418eef64fe30af65f7372847 467 SUPERFAMILY SSF55486 2 465 4.88E-93 T 31-10-2018 DFR86_04680 15163f66418eef64fe30af65f7372847 467 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 9 465 7.2E-84 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR86_04680 15163f66418eef64fe30af65f7372847 467 Gene3D G3DSA:1.10.1370.30 1 465 3.8E-157 T 31-10-2018 DFR86_04680 15163f66418eef64fe30af65f7372847 467 PIRSF PIRSF006615 1 467 3.0E-172 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR86_04680 15163f66418eef64fe30af65f7372847 467 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 130 150 3.8E-54 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR86_04680 15163f66418eef64fe30af65f7372847 467 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 377 398 3.8E-54 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR86_04680 15163f66418eef64fe30af65f7372847 467 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 247 266 3.8E-54 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR86_04680 15163f66418eef64fe30af65f7372847 467 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 354 371 3.8E-54 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR86_04680 15163f66418eef64fe30af65f7372847 467 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 210 226 3.8E-54 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR86_04680 15163f66418eef64fe30af65f7372847 467 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 227 246 3.8E-54 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR86_04680 15163f66418eef64fe30af65f7372847 467 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 274 290 3.8E-54 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR86_10045 ce9a83aa7271b2ebcba3731057cc19ba 417 SUPERFAMILY SSF55909 3 417 7.2E-74 T 31-10-2018 DFR86_10045 ce9a83aa7271b2ebcba3731057cc19ba 417 Pfam PF02274 Amidinotransferase 16 414 2.4E-47 T 31-10-2018 DFR86_10045 ce9a83aa7271b2ebcba3731057cc19ba 417 PRINTS PR01466 Bacterial arginine deiminase signature 148 166 4.4E-10 T 31-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 DFR86_10045 ce9a83aa7271b2ebcba3731057cc19ba 417 PRINTS PR01466 Bacterial arginine deiminase signature 176 191 4.4E-10 T 31-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 DFR86_10045 ce9a83aa7271b2ebcba3731057cc19ba 417 PRINTS PR01466 Bacterial arginine deiminase signature 398 416 4.4E-10 T 31-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 DFR86_05020 fb5d15b09099cdfcebbbeb1f4e50ce6e 135 SUPERFAMILY SSF54637 5 132 2.8E-31 T 31-10-2018 IPR029069 HotDog domain superfamily DFR86_05020 fb5d15b09099cdfcebbbeb1f4e50ce6e 135 PIRSF PIRSF003230 1 135 3.0E-20 T 31-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 DFR86_05020 fb5d15b09099cdfcebbbeb1f4e50ce6e 135 Gene3D G3DSA:3.10.129.10 2 133 7.6E-31 T 31-10-2018 DFR86_05020 fb5d15b09099cdfcebbbeb1f4e50ce6e 135 Pfam PF13279 Thioesterase-like superfamily 13 131 2.1E-8 T 31-10-2018 DFR86_04430 bf5150b4d576ed368f411dd6047f9b81 695 SUPERFAMILY SSF90123 111 434 7.46E-77 T 31-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 DFR86_04430 bf5150b4d576ed368f411dd6047f9b81 695 Pfam PF00005 ABC transporter 462 610 5.2E-36 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_04430 bf5150b4d576ed368f411dd6047f9b81 695 ProSitePatterns PS00211 ABC transporters family signature. 582 596 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_04430 bf5150b4d576ed368f411dd6047f9b81 695 SMART SM00382 470 656 4.6E-18 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_04430 bf5150b4d576ed368f411dd6047f9b81 695 Pfam PF00664 ABC transporter transmembrane region 129 399 1.8E-38 T 31-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 DFR86_04430 bf5150b4d576ed368f411dd6047f9b81 695 Gene3D G3DSA:3.40.50.300 441 687 4.9E-88 T 31-10-2018 DFR86_04430 bf5150b4d576ed368f411dd6047f9b81 695 SUPERFAMILY SSF52540 435 677 6.71E-84 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04430 bf5150b4d576ed368f411dd6047f9b81 695 Gene3D G3DSA:1.20.1560.10 93 432 6.7E-83 T 31-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 DFR86_00615 7a851ca023428f4de6862b2f4902ede6 351 SUPERFAMILY SSF46785 279 350 1.53E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_00615 7a851ca023428f4de6862b2f4902ede6 351 Pfam PF01637 ATPase domain predominantly from Archaea 17 246 3.4E-22 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR86_00615 7a851ca023428f4de6862b2f4902ede6 351 Gene3D G3DSA:3.40.50.300 3 203 4.7E-50 T 31-10-2018 DFR86_00615 7a851ca023428f4de6862b2f4902ede6 351 SUPERFAMILY SSF52540 5 279 1.63E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00615 7a851ca023428f4de6862b2f4902ede6 351 Gene3D G3DSA:1.10.10.10 283 351 1.2E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_00615 7a851ca023428f4de6862b2f4902ede6 351 Gene3D G3DSA:1.10.8.60 205 282 1.6E-25 T 31-10-2018 DFR86_05780 27ad6363ea3af708f880f4617d301feb 115 SUPERFAMILY SSF52080 7 114 1.44E-22 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily DFR86_05780 27ad6363ea3af708f880f4617d301feb 115 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 2 115 25.791 T 31-10-2018 IPR022947 Ribosomal protein L18e, archaea DFR86_05780 27ad6363ea3af708f880f4617d301feb 115 Gene3D G3DSA:3.100.10.10 3 114 7.2E-30 T 31-10-2018 DFR86_05780 27ad6363ea3af708f880f4617d301feb 115 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 41 95 2.1E-6 T 31-10-2018 IPR021131 Ribosomal protein L18e/L15P DFR86_07015 8d4096447737191fcfeb90bce64ae9df 529 Pfam PF06418 CTP synthase N-terminus 3 267 1.9E-123 T 31-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 DFR86_07015 8d4096447737191fcfeb90bce64ae9df 529 SUPERFAMILY SSF52317 289 527 4.22E-76 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_07015 8d4096447737191fcfeb90bce64ae9df 529 Gene3D G3DSA:3.40.50.300 1 285 3.1E-134 T 31-10-2018 DFR86_07015 8d4096447737191fcfeb90bce64ae9df 529 Gene3D G3DSA:3.40.50.880 286 529 1.0E-106 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_07015 8d4096447737191fcfeb90bce64ae9df 529 SUPERFAMILY SSF52540 2 268 1.95E-118 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07015 8d4096447737191fcfeb90bce64ae9df 529 TIGRFAM TIGR00337 PyrG: CTP synthase 2 526 1.5E-235 T 31-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 DFR86_07015 8d4096447737191fcfeb90bce64ae9df 529 Hamap MF_01227 CTP synthase [pyrG]. 2 529 50.207 T 31-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 DFR86_07015 8d4096447737191fcfeb90bce64ae9df 529 Pfam PF00117 Glutamine amidotransferase class-I 302 526 4.1E-53 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR86_10650 83d5cfc3494c3de0df3d8878b9a37ebd 205 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 15 164 6.9E-13 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DFR86_10650 83d5cfc3494c3de0df3d8878b9a37ebd 205 Gene3D G3DSA:3.40.50.300 11 193 8.3E-17 T 31-10-2018 DFR86_10650 83d5cfc3494c3de0df3d8878b9a37ebd 205 SUPERFAMILY SSF52540 11 169 9.22E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00560 11c7cf7a171549c26696c59dcaa8d914 65 Pfam PF11755 Protein of unknown function (DUF3311) 12 55 2.1E-10 T 31-10-2018 IPR021741 Protein of unknown function DUF3311 DFR86_11230 e663d44b06d0ab338e3bc2ab7c960ac9 374 PIRSF PIRSF037420 21 374 7.0E-121 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR86_11230 e663d44b06d0ab338e3bc2ab7c960ac9 374 Pfam PF13186 Iron-sulfur cluster-binding domain 285 323 1.8E-7 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR86_11230 e663d44b06d0ab338e3bc2ab7c960ac9 374 SUPERFAMILY SSF102114 36 348 1.96E-70 T 31-10-2018 DFR86_11230 e663d44b06d0ab338e3bc2ab7c960ac9 374 Gene3D G3DSA:3.20.20.70 30 361 7.5E-61 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_11230 e663d44b06d0ab338e3bc2ab7c960ac9 374 SMART SM00729 36 238 1.8E-5 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_11230 e663d44b06d0ab338e3bc2ab7c960ac9 374 Pfam PF04055 Radical SAM superfamily 42 197 1.7E-25 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_11230 e663d44b06d0ab338e3bc2ab7c960ac9 374 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 285 367 5.9E-10 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR86_11230 e663d44b06d0ab338e3bc2ab7c960ac9 374 Pfam PF13353 4Fe-4S single cluster domain 43 129 2.3E-7 T 31-10-2018 DFR86_10790 53c650bca2914a928e92e305c57c11d7 124 Gene3D G3DSA:3.30.310.70 2 123 2.6E-14 T 31-10-2018 IPR035923 TT1751-like domain superfamily DFR86_10790 53c650bca2914a928e92e305c57c11d7 124 SUPERFAMILY SSF103247 4 119 3.53E-27 T 31-10-2018 IPR035923 TT1751-like domain superfamily DFR86_10790 53c650bca2914a928e92e305c57c11d7 124 Pfam PF03625 Domain of unknown function DUF302 32 93 1.0E-14 T 31-10-2018 IPR005180 Domain of unknown function DUF302 DFR86_06905 bdd3ea662636b744dce34a02e5a0d889 181 Hamap MF_00239 Cytidylate kinase [cmk]. 1 174 42.128 T 31-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 DFR86_06905 bdd3ea662636b744dce34a02e5a0d889 181 Pfam PF13238 AAA domain 3 127 2.5E-16 T 31-10-2018 DFR86_06905 bdd3ea662636b744dce34a02e5a0d889 181 Gene3D G3DSA:3.40.50.300 1 174 2.3E-43 T 31-10-2018 DFR86_06905 bdd3ea662636b744dce34a02e5a0d889 181 SUPERFAMILY SSF52540 1 176 3.98E-27 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06905 bdd3ea662636b744dce34a02e5a0d889 181 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 1 171 3.0E-60 T 31-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 DFR86_08420 bb6f511c06e6a929af118039f15ad7af 155 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 4 150 1.5E-51 T 31-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 DFR86_08420 bb6f511c06e6a929af118039f15ad7af 155 SUPERFAMILY SSF54893 2 99 8.76E-33 T 31-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily DFR86_08420 bb6f511c06e6a929af118039f15ad7af 155 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 101 149 2.8E-18 T 31-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal DFR86_08420 bb6f511c06e6a929af118039f15ad7af 155 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 6 96 2.8E-32 T 31-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal DFR86_08420 bb6f511c06e6a929af118039f15ad7af 155 SUPERFAMILY SSF57825 100 153 3.66E-16 T 31-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily DFR86_08420 bb6f511c06e6a929af118039f15ad7af 155 Gene3D G3DSA:2.30.30.20 99 155 2.5E-21 T 31-10-2018 DFR86_08420 bb6f511c06e6a929af118039f15ad7af 155 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 7 98 1.0E-25 T 31-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal DFR86_08420 bb6f511c06e6a929af118039f15ad7af 155 Gene3D G3DSA:3.30.70.140 1 98 1.2E-36 T 31-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily DFR86_08420 bb6f511c06e6a929af118039f15ad7af 155 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 2 151 33.175 T 31-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 DFR86_01965 9722272517adcbbdd5d84f3b4b170f69 415 Pfam PF07690 Major Facilitator Superfamily 32 379 8.1E-24 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_01965 9722272517adcbbdd5d84f3b4b170f69 415 SUPERFAMILY SSF103473 14 409 1.22E-33 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_01965 9722272517adcbbdd5d84f3b4b170f69 415 Gene3D G3DSA:1.20.1250.20 9 410 3.8E-28 T 31-10-2018 DFR86_01775 c7daead08e5d4dca91c8e0e23afeb6d4 215 Hamap MF_00401 Peroxiredoxin. 2 206 43.422 T 31-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DFR86_01775 c7daead08e5d4dca91c8e0e23afeb6d4 215 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 158 191 2.2E-7 T 31-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_01775 c7daead08e5d4dca91c8e0e23afeb6d4 215 PIRSF PIRSF000239 1 209 9.6E-68 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_01775 c7daead08e5d4dca91c8e0e23afeb6d4 215 SUPERFAMILY SSF52833 1 206 1.41E-61 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_01775 c7daead08e5d4dca91c8e0e23afeb6d4 215 Pfam PF00578 AhpC/TSA family 6 134 4.0E-31 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_01775 c7daead08e5d4dca91c8e0e23afeb6d4 215 Gene3D G3DSA:3.30.1020.20 144 215 7.6E-14 T 31-10-2018 DFR86_01775 c7daead08e5d4dca91c8e0e23afeb6d4 215 Gene3D G3DSA:3.40.30.10 1 143 1.6E-42 T 31-10-2018 DFR86_01065 9fa0565c7c67782d22a978c12320b6cd 664 PIRSF PIRSF002741 16 663 4.3E-37 T 31-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DFR86_01065 9fa0565c7c67782d22a978c12320b6cd 664 Gene3D G3DSA:3.10.105.10 392 629 9.2E-30 T 31-10-2018 DFR86_01065 9fa0565c7c67782d22a978c12320b6cd 664 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 110 578 5.5E-69 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain DFR86_01065 9fa0565c7c67782d22a978c12320b6cd 664 SUPERFAMILY SSF53850 70 658 1.28E-74 T 31-10-2018 DFR86_08095 5a6032c7fcfb9ab4c3db8072ee9374c2 308 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 295 63.059 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 DFR86_08095 5a6032c7fcfb9ab4c3db8072ee9374c2 308 Pfam PF03186 CobD/Cbib protein 5 273 7.5E-73 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 DFR86_08095 5a6032c7fcfb9ab4c3db8072ee9374c2 308 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 4 288 5.9E-61 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 31-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 35.292 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 Pfam PF00334 Nucleoside diphosphate kinase 5 137 5.5E-59 T 31-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 SMART SM00562 3 140 6.5E-84 T 31-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.0E-43 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 1.0E-43 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.0E-43 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.0E-43 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.0E-43 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 SUPERFAMILY SSF54919 1 138 1.31E-58 T 31-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_06265 5658b293fe2cacff38e674f7e9746d5d 145 Gene3D G3DSA:3.30.70.141 1 144 4.0E-62 T 31-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR86_07365 0084f163e53390d6d359c11fa7ebc7c9 149 SUPERFAMILY SSF55186 4 147 4.71E-32 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 DFR86_07365 0084f163e53390d6d359c11fa7ebc7c9 149 Gene3D G3DSA:3.30.980.10 8 146 2.7E-47 T 31-10-2018 DFR86_07365 0084f163e53390d6d359c11fa7ebc7c9 149 Gene3D G3DSA:3.30.54.20 71 117 2.7E-47 T 31-10-2018 DFR86_07365 0084f163e53390d6d359c11fa7ebc7c9 149 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 103 130 1.0E-5 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 DFR86_08185 4b3463c5859b0ce7f22c43332bf1b103 470 PIRSF PIRSF006060 1 451 9.3E-42 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_08185 4b3463c5859b0ce7f22c43332bf1b103 470 Pfam PF00324 Amino acid permease 17 366 1.7E-14 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR86_08185 4b3463c5859b0ce7f22c43332bf1b103 470 Gene3D G3DSA:1.20.1740.10 3 381 7.8E-23 T 31-10-2018 DFR86_02985 eac6b506cc1b05afac438d2b2936a111 168 Pfam PF01799 [2Fe-2S] binding domain 81 154 9.1E-34 T 31-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DFR86_02985 eac6b506cc1b05afac438d2b2936a111 168 SUPERFAMILY SSF47741 92 164 2.62E-35 T 31-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily DFR86_02985 eac6b506cc1b05afac438d2b2936a111 168 Gene3D G3DSA:1.10.150.120 85 166 1.2E-36 T 31-10-2018 DFR86_02985 eac6b506cc1b05afac438d2b2936a111 168 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 67 6.7E-8 T 31-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DFR86_02985 eac6b506cc1b05afac438d2b2936a111 168 Gene3D G3DSA:3.10.20.30 1 84 1.7E-31 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR86_02985 eac6b506cc1b05afac438d2b2936a111 168 SUPERFAMILY SSF54292 8 95 1.26E-22 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR86_01755 f67e0aa4909a814b00ec94b20b3b6a6f 153 SUPERFAMILY SSF52799 1 143 3.13E-35 T 31-10-2018 IPR029021 Protein-tyrosine phosphatase-like DFR86_01755 f67e0aa4909a814b00ec94b20b3b6a6f 153 SMART SM00404 58 147 1.8E-14 T 31-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic DFR86_01755 f67e0aa4909a814b00ec94b20b3b6a6f 153 Gene3D G3DSA:3.90.190.10 1 148 1.6E-42 T 31-10-2018 IPR029021 Protein-tyrosine phosphatase-like DFR86_01755 f67e0aa4909a814b00ec94b20b3b6a6f 153 Pfam PF00102 Protein-tyrosine phosphatase 89 143 2.5E-11 T 31-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 DFR86_01755 f67e0aa4909a814b00ec94b20b3b6a6f 153 PRINTS PR00700 Protein tyrosine phosphatase signature 115 130 6.9E-9 T 31-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 DFR86_01755 f67e0aa4909a814b00ec94b20b3b6a6f 153 PRINTS PR00700 Protein tyrosine phosphatase signature 89 107 6.9E-9 T 31-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 DFR86_01755 f67e0aa4909a814b00ec94b20b3b6a6f 153 PRINTS PR00700 Protein tyrosine phosphatase signature 131 141 6.9E-9 T 31-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 DFR86_01755 f67e0aa4909a814b00ec94b20b3b6a6f 153 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 92 102 - T 31-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 DFR86_02945 57c538c3f9f86e0df28dea4a0484002c 253 SUPERFAMILY SSF53335 3 253 6.84E-49 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_02945 57c538c3f9f86e0df28dea4a0484002c 253 Gene3D G3DSA:3.40.50.150 8 253 1.4E-50 T 31-10-2018 DFR86_02945 57c538c3f9f86e0df28dea4a0484002c 253 Pfam PF02475 Met-10+ like-protein 10 205 1.1E-44 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 DFR86_04235 ee47238ea0b107e14b19d020980a83df 312 SUPERFAMILY SSF50022 2 114 2.23E-30 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_04235 ee47238ea0b107e14b19d020980a83df 312 Pfam PF00355 Rieske [2Fe-2S] domain 4 82 1.3E-19 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR86_04235 ee47238ea0b107e14b19d020980a83df 312 Gene3D G3DSA:3.30.530.90 120 308 8.4E-13 T 31-10-2018 DFR86_04235 ee47238ea0b107e14b19d020980a83df 312 Gene3D G3DSA:2.102.10.10 1 119 1.9E-31 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_04235 ee47238ea0b107e14b19d020980a83df 312 SUPERFAMILY SSF55961 112 308 1.63E-24 T 31-10-2018 DFR86_08050 598e6ffa6a940cdf9d7174d90e00ecc9 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 31-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site DFR86_08050 598e6ffa6a940cdf9d7174d90e00ecc9 356 SUPERFAMILY SSF53092 4 128 8.72E-19 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DFR86_08050 598e6ffa6a940cdf9d7174d90e00ecc9 356 SUPERFAMILY SSF55920 129 356 6.8E-66 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like DFR86_08050 598e6ffa6a940cdf9d7174d90e00ecc9 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 130 1.1E-15 T 31-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 DFR86_08050 598e6ffa6a940cdf9d7174d90e00ecc9 356 Pfam PF00557 Metallopeptidase family M24 139 337 1.1E-57 T 31-10-2018 IPR000994 Peptidase M24 DFR86_08050 598e6ffa6a940cdf9d7174d90e00ecc9 356 Gene3D G3DSA:3.40.350.10 2 129 2.0E-23 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DFR86_08050 598e6ffa6a940cdf9d7174d90e00ecc9 356 Gene3D G3DSA:3.90.230.10 130 356 3.7E-70 T 31-10-2018 DFR86_05935 4b81eb035b0afde078c0bfd7b519aab6 181 PIRSF PIRSF005285 5 181 4.7E-61 T 31-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 DFR86_05935 4b81eb035b0afde078c0bfd7b519aab6 181 SUPERFAMILY SSF55267 2 81 3.14E-15 T 31-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 DFR86_05935 4b81eb035b0afde078c0bfd7b519aab6 181 Gene3D G3DSA:3.40.1170.20 2 86 2.8E-26 T 31-10-2018 DFR86_05935 4b81eb035b0afde078c0bfd7b519aab6 181 TIGRFAM TIGR00324 endA: tRNA-intron lyase 46 179 7.8E-34 T 31-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR86_05935 4b81eb035b0afde078c0bfd7b519aab6 181 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 2 78 5.7E-21 T 31-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR86_05935 4b81eb035b0afde078c0bfd7b519aab6 181 SUPERFAMILY SSF53032 87 171 8.89E-24 T 31-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR86_05935 4b81eb035b0afde078c0bfd7b519aab6 181 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 2 181 33.815 T 31-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 DFR86_05935 4b81eb035b0afde078c0bfd7b519aab6 181 Gene3D G3DSA:3.40.1350.10 87 181 5.1E-31 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 DFR86_05935 4b81eb035b0afde078c0bfd7b519aab6 181 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 88 173 7.1E-26 T 31-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR86_07290 475fed9e4519e296fdc4c734c34c8b24 141 Gene3D G3DSA:3.30.70.920 57 141 1.1E-14 T 31-10-2018 DFR86_07290 475fed9e4519e296fdc4c734c34c8b24 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 1.4E-12 T 31-10-2018 DFR86_07290 475fed9e4519e296fdc4c734c34c8b24 141 Gene3D G3DSA:1.10.10.10 1 56 2.1E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_07290 475fed9e4519e296fdc4c734c34c8b24 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.5E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_07290 475fed9e4519e296fdc4c734c34c8b24 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.5E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_07290 475fed9e4519e296fdc4c734c34c8b24 141 SUPERFAMILY SSF54909 64 140 6.3E-13 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR86_07290 475fed9e4519e296fdc4c734c34c8b24 141 SUPERFAMILY SSF46785 4 57 7.06E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_07290 475fed9e4519e296fdc4c734c34c8b24 141 SMART SM00344 5 109 3.9E-22 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR86_07290 475fed9e4519e296fdc4c734c34c8b24 141 Pfam PF01037 Lrp/AsnC ligand binding domain 77 138 4.7E-11 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR86_01655 2ada209dfe946f500c7501d40f149726 137 SUPERFAMILY SSF52980 6 120 2.15E-26 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR86_01655 2ada209dfe946f500c7501d40f149726 137 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 102 5.2E-26 T 31-10-2018 IPR002732 Holliday junction resolvase Hjc DFR86_01655 2ada209dfe946f500c7501d40f149726 137 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 125 1.0E-34 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal DFR86_01655 2ada209dfe946f500c7501d40f149726 137 Gene3D G3DSA:3.40.1350.10 1 136 2.5E-39 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 DFR86_01655 2ada209dfe946f500c7501d40f149726 137 PIRSF PIRSF004985 1 135 2.4E-35 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal DFR86_10320 cc0605af1141d9102345954252a79611 430 Pfam PF13173 AAA domain 44 174 2.0E-32 T 31-10-2018 DFR86_10320 cc0605af1141d9102345954252a79611 430 Gene3D G3DSA:3.40.50.300 72 164 1.4E-5 T 31-10-2018 DFR86_10320 cc0605af1141d9102345954252a79611 430 SUPERFAMILY SSF52540 44 236 9.21E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_10320 cc0605af1141d9102345954252a79611 430 Pfam PF13635 Domain of unknown function (DUF4143) 231 366 3.3E-12 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 DFR86_06340 e9e7f6093fe0a52ccbef3b63aef4ad19 338 Gene3D G3DSA:3.40.440.10 2 334 2.8E-100 T 31-10-2018 DFR86_06340 e9e7f6093fe0a52ccbef3b63aef4ad19 338 SUPERFAMILY SSF52540 2 330 7.33E-84 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06340 e9e7f6093fe0a52ccbef3b63aef4ad19 338 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 314 327 - T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR86_06340 e9e7f6093fe0a52ccbef3b63aef4ad19 338 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 338 64.412 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 DFR86_06340 e9e7f6093fe0a52ccbef3b63aef4ad19 338 SMART SM00788 2 329 1.0E-111 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 DFR86_06340 e9e7f6093fe0a52ccbef3b63aef4ad19 338 Pfam PF00709 Adenylosuccinate synthetase 4 138 1.1E-22 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 DFR86_06340 e9e7f6093fe0a52ccbef3b63aef4ad19 338 Pfam PF00709 Adenylosuccinate synthetase 286 328 1.9E-5 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 DFR86_06340 e9e7f6093fe0a52ccbef3b63aef4ad19 338 Pfam PF00709 Adenylosuccinate synthetase 142 283 1.2E-35 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 DFR86_05855 35429eeb741a871a197975553d1415fb 220 SUPERFAMILY SSF81301 11 67 4.15E-11 T 31-10-2018 DFR86_05855 35429eeb741a871a197975553d1415fb 220 Pfam PF01909 Nucleotidyltransferase domain 21 72 1.6E-8 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR86_05855 35429eeb741a871a197975553d1415fb 220 Gene3D G3DSA:3.30.460.10 4 112 2.9E-9 T 31-10-2018 DFR86_05855 35429eeb741a871a197975553d1415fb 220 PIRSF PIRSF005928 1 220 1.4E-77 T 31-10-2018 IPR009185 Predicted nucleotidyltransferase DFR86_10905 6fbedb155d19283056a36d537334e342 406 Gene3D G3DSA:3.50.50.60 6 348 5.7E-53 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_10905 6fbedb155d19283056a36d537334e342 406 SUPERFAMILY SSF54373 176 262 5.89E-5 T 31-10-2018 DFR86_10905 6fbedb155d19283056a36d537334e342 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.6E-5 T 31-10-2018 DFR86_10905 6fbedb155d19283056a36d537334e342 406 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 1.6E-5 T 31-10-2018 DFR86_10905 6fbedb155d19283056a36d537334e342 406 Gene3D G3DSA:3.30.9.10 72 361 5.7E-53 T 31-10-2018 DFR86_10905 6fbedb155d19283056a36d537334e342 406 Pfam PF12831 FAD dependent oxidoreductase 6 161 7.3E-11 T 31-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal DFR86_10905 6fbedb155d19283056a36d537334e342 406 SUPERFAMILY SSF51905 5 348 5.86E-32 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_07855 5acd763626a0a8fb4b5bf9e08a5d05f0 348 Gene3D G3DSA:3.40.50.2000 173 328 5.7E-34 T 31-10-2018 DFR86_07855 5acd763626a0a8fb4b5bf9e08a5d05f0 348 Gene3D G3DSA:3.40.50.2000 1 172 3.8E-21 T 31-10-2018 DFR86_07855 5acd763626a0a8fb4b5bf9e08a5d05f0 348 SUPERFAMILY SSF53756 10 346 3.65E-69 T 31-10-2018 DFR86_07855 5acd763626a0a8fb4b5bf9e08a5d05f0 348 Pfam PF00534 Glycosyl transferases group 1 164 321 1.1E-31 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR86_04485 cc2f2397884bf5916d4a424b0c324711 370 SUPERFAMILY SSF103473 6 309 2.79E-5 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_11195 b0000b8e5d396078d3cc572baf6bd068 381 Pfam PF01136 Peptidase family U32 85 149 3.2E-9 T 31-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 DFR86_09800 a955b5ee55b4d48cccc6d2c1b0a9698f 99 Gene3D G3DSA:1.10.20.60 3 95 1.4E-20 T 31-10-2018 DFR86_09800 a955b5ee55b4d48cccc6d2c1b0a9698f 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 4 98 21.317 T 31-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 DFR86_09800 a955b5ee55b4d48cccc6d2c1b0a9698f 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 24 91 1.8E-17 T 31-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 DFR86_09800 a955b5ee55b4d48cccc6d2c1b0a9698f 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 7 97 4.0E-27 T 31-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 DFR86_09800 a955b5ee55b4d48cccc6d2c1b0a9698f 99 SUPERFAMILY SSF141000 7 94 2.48E-21 T 31-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 DFR86_08170 dd35f4eed07b4e3856d1ce5b7226255a 763 Pfam PF05127 Helicase 228 406 1.6E-49 T 31-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 DFR86_08170 dd35f4eed07b4e3856d1ce5b7226255a 763 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 21 741 40.135 T 31-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 DFR86_08170 dd35f4eed07b4e3856d1ce5b7226255a 763 SUPERFAMILY SSF52540 138 352 1.8E-11 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08170 dd35f4eed07b4e3856d1ce5b7226255a 763 SUPERFAMILY SSF55729 509 587 3.01E-8 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR86_08170 dd35f4eed07b4e3856d1ce5b7226255a 763 Pfam PF08351 Domain of unknown function (DUF1726) 84 169 1.4E-24 T 31-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 DFR86_08170 dd35f4eed07b4e3856d1ce5b7226255a 763 Pfam PF13718 GNAT acetyltransferase 2 439 553 6.9E-27 T 31-10-2018 IPR000182 GNAT domain DFR86_08170 dd35f4eed07b4e3856d1ce5b7226255a 763 Pfam PF13718 GNAT acetyltransferase 2 555 603 2.5E-6 T 31-10-2018 IPR000182 GNAT domain DFR86_08170 dd35f4eed07b4e3856d1ce5b7226255a 763 Gene3D G3DSA:3.40.630.30 399 601 2.2E-50 T 31-10-2018 DFR86_08170 dd35f4eed07b4e3856d1ce5b7226255a 763 Gene3D G3DSA:3.40.50.12320 223 396 3.0E-27 T 31-10-2018 DFR86_07775 f2ef373165eb18ce49b9e15880ab6acd 370 Pfam PF07690 Major Facilitator Superfamily 8 333 2.5E-35 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_07775 f2ef373165eb18ce49b9e15880ab6acd 370 Gene3D G3DSA:1.20.1250.20 187 369 4.1E-14 T 31-10-2018 DFR86_07775 f2ef373165eb18ce49b9e15880ab6acd 370 Gene3D G3DSA:1.20.1250.20 2 186 2.6E-22 T 31-10-2018 DFR86_07775 f2ef373165eb18ce49b9e15880ab6acd 370 SUPERFAMILY SSF103473 3 368 5.1E-46 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_04165 66bd3c984875e3c40eb101afa71a3987 406 SUPERFAMILY SSF56176 20 200 2.66E-37 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_04165 66bd3c984875e3c40eb101afa71a3987 406 Pfam PF01565 FAD binding domain 46 177 1.2E-26 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_04165 66bd3c984875e3c40eb101afa71a3987 406 Gene3D G3DSA:3.30.43.10 9 95 1.0E-17 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR86_04165 66bd3c984875e3c40eb101afa71a3987 406 Gene3D G3DSA:3.30.465.10 96 203 1.8E-10 T 31-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 DFR86_08025 3c1ece5ee23eb9ce853f023447a7aa7f 291 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 230 243 - T 31-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DFR86_08025 3c1ece5ee23eb9ce853f023447a7aa7f 291 Hamap MF_01987 Ribokinase [rbsK]. 1 283 20.462 T 31-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 DFR86_08025 3c1ece5ee23eb9ce853f023447a7aa7f 291 Gene3D G3DSA:3.40.1190.20 1 291 1.8E-80 T 31-10-2018 IPR029056 Ribokinase-like DFR86_08025 3c1ece5ee23eb9ce853f023447a7aa7f 291 SUPERFAMILY SSF53613 2 273 4.52E-68 T 31-10-2018 IPR029056 Ribokinase-like DFR86_08025 3c1ece5ee23eb9ce853f023447a7aa7f 291 Pfam PF00294 pfkB family carbohydrate kinase 2 275 5.3E-60 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB DFR86_08025 3c1ece5ee23eb9ce853f023447a7aa7f 291 PRINTS PR00990 Ribokinase signature 31 50 1.1E-24 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR86_08025 3c1ece5ee23eb9ce853f023447a7aa7f 291 PRINTS PR00990 Ribokinase signature 162 177 1.1E-24 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR86_08025 3c1ece5ee23eb9ce853f023447a7aa7f 291 PRINTS PR00990 Ribokinase signature 4 25 1.1E-24 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR86_08025 3c1ece5ee23eb9ce853f023447a7aa7f 291 PRINTS PR00990 Ribokinase signature 201 212 1.1E-24 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR86_04990 e93709f8b1c8cc17d080d5aae4be7cfc 212 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 199 2.9E-30 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 DFR86_04990 e93709f8b1c8cc17d080d5aae4be7cfc 212 SUPERFAMILY SSF52540 1 210 7.72E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04990 e93709f8b1c8cc17d080d5aae4be7cfc 212 Pfam PF02223 Thymidylate kinase 8 199 1.3E-25 T 31-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DFR86_04990 e93709f8b1c8cc17d080d5aae4be7cfc 212 Gene3D G3DSA:3.40.50.300 1 212 7.5E-65 T 31-10-2018 DFR86_04990 e93709f8b1c8cc17d080d5aae4be7cfc 212 Hamap MF_00165 Thymidylate kinase [tmk]. 4 208 17.99 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 DFR86_10195 8caacf42bf5ff2a819f572681a1c73b8 85 Gene3D G3DSA:3.30.110.40 2 70 1.9E-8 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_10195 8caacf42bf5ff2a819f572681a1c73b8 85 SUPERFAMILY SSF64307 1 71 2.22E-16 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_10195 8caacf42bf5ff2a819f572681a1c73b8 85 Pfam PF01206 Sulfurtransferase TusA 3 70 2.3E-14 T 31-10-2018 IPR001455 TusA-like domain DFR86_01050 7456dc8be9cf0f21abbde933abaf3373 369 SUPERFAMILY SSF53901 227 358 1.62E-15 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_01050 7456dc8be9cf0f21abbde933abaf3373 369 Pfam PF02803 Thiolase, C-terminal domain 255 352 9.0E-5 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 DFR86_01050 7456dc8be9cf0f21abbde933abaf3373 369 SUPERFAMILY SSF53901 11 223 1.39E-13 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_01050 7456dc8be9cf0f21abbde933abaf3373 369 Gene3D G3DSA:3.40.47.10 2 369 4.1E-56 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_01660 d7ff288c3e40437158dffabc44fea272 256 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 2.6E-12 T 31-10-2018 DFR86_01660 d7ff288c3e40437158dffabc44fea272 256 SMART SM00344 1 84 0.0085 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR86_01660 d7ff288c3e40437158dffabc44fea272 256 SUPERFAMILY SSF46785 122 179 4.01E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_01660 d7ff288c3e40437158dffabc44fea272 256 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 8.0E-6 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_01660 d7ff288c3e40437158dffabc44fea272 256 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 8.0E-6 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_01660 d7ff288c3e40437158dffabc44fea272 256 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 8.0E-6 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_01660 d7ff288c3e40437158dffabc44fea272 256 Gene3D G3DSA:1.10.10.10 1 51 1.0E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_01660 d7ff288c3e40437158dffabc44fea272 256 Pfam PF08279 HTH domain 136 171 3.8E-6 T 31-10-2018 IPR013196 Helix-turn-helix, type 11 DFR86_01660 d7ff288c3e40437158dffabc44fea272 256 SUPERFAMILY SSF46785 1 57 2.57E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_01660 d7ff288c3e40437158dffabc44fea272 256 Gene3D G3DSA:1.10.10.10 132 180 2.4E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_09515 f9b382f4034ae3298b84e91ab3accc0d 248 Gene3D G3DSA:3.20.20.70 1 248 2.2E-96 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_09515 f9b382f4034ae3298b84e91ab3accc0d 248 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 48 62 - T 31-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 DFR86_09515 f9b382f4034ae3298b84e91ab3accc0d 248 Pfam PF00218 Indole-3-glycerol phosphate synthase 11 240 1.4E-79 T 31-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 DFR86_09515 f9b382f4034ae3298b84e91ab3accc0d 248 SUPERFAMILY SSF51366 27 241 6.24E-69 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR86_09515 f9b382f4034ae3298b84e91ab3accc0d 248 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 30 248 36.112 T 31-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 DFR86_08190 e945b14f92a085aef16b426ff2dbeec5 131 Pfam PF00582 Universal stress protein family 2 131 1.7E-27 T 31-10-2018 IPR006016 UspA DFR86_08190 e945b14f92a085aef16b426ff2dbeec5 131 PRINTS PR01438 Universal stress protein signature 109 131 9.3E-10 T 31-10-2018 IPR006015 Universal stress protein A DFR86_08190 e945b14f92a085aef16b426ff2dbeec5 131 PRINTS PR01438 Universal stress protein signature 91 103 9.3E-10 T 31-10-2018 IPR006015 Universal stress protein A DFR86_08190 e945b14f92a085aef16b426ff2dbeec5 131 SUPERFAMILY SSF52402 1 131 3.93E-30 T 31-10-2018 DFR86_08190 e945b14f92a085aef16b426ff2dbeec5 131 Gene3D G3DSA:3.40.50.620 1 131 2.0E-31 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 Pfam PF14759 Reductase C-terminal 318 406 6.2E-15 T 31-10-2018 IPR028202 Reductase, C-terminal DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 SUPERFAMILY SSF55424 310 406 9.48E-18 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.1E-27 T 31-10-2018 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 3.1E-27 T 31-10-2018 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 3.1E-27 T 31-10-2018 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 3.1E-27 T 31-10-2018 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.1E-27 T 31-10-2018 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 Gene3D G3DSA:3.30.390.30 318 407 1.2E-13 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 Gene3D G3DSA:3.50.50.60 9 306 7.3E-100 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 SUPERFAMILY SSF51905 147 309 1.73E-30 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 Gene3D G3DSA:3.50.50.60 117 235 7.3E-100 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 298 2.3E-63 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 SUPERFAMILY SSF51905 2 192 1.79E-42 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 4.5E-19 T 31-10-2018 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 4.5E-19 T 31-10-2018 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.5E-19 T 31-10-2018 DFR86_00625 ce2f94b9aa795dfb06a2ba68dc201916 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 4.5E-19 T 31-10-2018 DFR86_03980 12395d27b73882f27a1e51c40cb26ee0 158 Gene3D G3DSA:3.40.50.1450 1 132 3.8E-17 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily DFR86_03980 12395d27b73882f27a1e51c40cb26ee0 158 SUPERFAMILY SSF53163 1 141 4.18E-21 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily DFR86_03980 12395d27b73882f27a1e51c40cb26ee0 158 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 130 4.9E-15 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DFR86_03980 12395d27b73882f27a1e51c40cb26ee0 158 Pfam PF01750 Hydrogenase maturation protease 29 127 1.9E-4 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DFR86_01225 bbf600af2fe8b3d420ce798c49764696 351 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 16 348 2.3E-56 T 31-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR86_01225 bbf600af2fe8b3d420ce798c49764696 351 SUPERFAMILY SSF111342 8 281 5.1E-66 T 31-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR86_01225 bbf600af2fe8b3d420ce798c49764696 351 PIRSF PIRSF026782 5 351 2.0E-96 T 31-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR86_01225 bbf600af2fe8b3d420ce798c49764696 351 Gene3D G3DSA:3.30.2110.10 10 184 4.9E-34 T 31-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR86_01225 bbf600af2fe8b3d420ce798c49764696 351 Pfam PF01888 CbiD 9 264 4.3E-63 T 31-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR86_01225 bbf600af2fe8b3d420ce798c49764696 351 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 8 333 23.572 T 31-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR86_05435 bc9cd90563898f5127e7f1b88a0e24c1 141 Gene3D G3DSA:3.40.50.620 1 141 1.4E-42 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_05435 bc9cd90563898f5127e7f1b88a0e24c1 141 SUPERFAMILY SSF52402 2 141 1.32E-39 T 31-10-2018 DFR86_05435 bc9cd90563898f5127e7f1b88a0e24c1 141 PIRSF PIRSF006276 1 141 1.2E-19 T 31-10-2018 IPR006015 Universal stress protein A DFR86_05435 bc9cd90563898f5127e7f1b88a0e24c1 141 Pfam PF00582 Universal stress protein family 1 141 5.7E-38 T 31-10-2018 IPR006016 UspA DFR86_05435 bc9cd90563898f5127e7f1b88a0e24c1 141 PRINTS PR01438 Universal stress protein signature 2 20 1.9E-20 T 31-10-2018 IPR006015 Universal stress protein A DFR86_05435 bc9cd90563898f5127e7f1b88a0e24c1 141 PRINTS PR01438 Universal stress protein signature 101 113 1.9E-20 T 31-10-2018 IPR006015 Universal stress protein A DFR86_05435 bc9cd90563898f5127e7f1b88a0e24c1 141 PRINTS PR01438 Universal stress protein signature 119 141 1.9E-20 T 31-10-2018 IPR006015 Universal stress protein A DFR86_10450 956c9f33d4358513995f7605a83a284a 179 Pfam PF08241 Methyltransferase domain 46 142 2.0E-13 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR86_10450 956c9f33d4358513995f7605a83a284a 179 Gene3D G3DSA:3.40.50.150 22 177 2.4E-20 T 31-10-2018 DFR86_10450 956c9f33d4358513995f7605a83a284a 179 SUPERFAMILY SSF53335 11 165 1.5E-17 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_05160 0512b98f159c54a7203c6097ba42fddb 604 Gene3D G3DSA:3.40.50.300 395 594 6.6E-20 T 31-10-2018 DFR86_05160 0512b98f159c54a7203c6097ba42fddb 604 SUPERFAMILY SSF52540 145 594 2.66E-30 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_05160 0512b98f159c54a7203c6097ba42fddb 604 SMART SM00382 187 556 0.0093 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_05160 0512b98f159c54a7203c6097ba42fddb 604 Pfam PF01935 Domain of unknown function DUF87 168 459 1.6E-13 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR86_05160 0512b98f159c54a7203c6097ba42fddb 604 Gene3D G3DSA:3.40.50.300 156 304 3.7E-12 T 31-10-2018 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 Pfam PF00083 Sugar (and other) transporter 27 461 1.2E-86 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 PRINTS PR00171 Sugar transporter signature 385 397 1.2E-15 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 PRINTS PR00171 Sugar transporter signature 34 44 1.2E-15 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 PRINTS PR00171 Sugar transporter signature 362 383 1.2E-15 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 PRINTS PR00171 Sugar transporter signature 269 279 1.2E-15 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 PRINTS PR00171 Sugar transporter signature 115 134 1.2E-15 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 SUPERFAMILY SSF103473 1 456 1.44E-59 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 15 457 2.7E-77 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 Gene3D G3DSA:1.20.1250.20 15 230 2.1E-50 T 31-10-2018 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 ProSitePatterns PS00216 Sugar transport proteins signature 1. 322 338 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_03685 891ad9ea1db526b93b8b48ffce73e0bc 487 Gene3D G3DSA:1.20.1250.20 234 467 1.2E-45 T 31-10-2018 DFR86_07795 dc186544aceb76aa936c6f72b0040238 399 Gene3D G3DSA:1.20.1250.20 4 395 6.1E-53 T 31-10-2018 DFR86_07795 dc186544aceb76aa936c6f72b0040238 399 ProSitePatterns PS00217 Sugar transport proteins signature 2. 103 128 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_07795 dc186544aceb76aa936c6f72b0040238 399 Pfam PF07690 Major Facilitator Superfamily 24 175 3.3E-20 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_07795 dc186544aceb76aa936c6f72b0040238 399 Pfam PF07690 Major Facilitator Superfamily 215 383 4.3E-10 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_07795 dc186544aceb76aa936c6f72b0040238 399 SUPERFAMILY SSF103473 7 386 5.49E-52 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_02930 e53a622e2e86c0191677af3128e2a3b6 332 SUPERFAMILY SSF51735 137 301 6.74E-26 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_02930 e53a622e2e86c0191677af3128e2a3b6 332 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 DFR86_02930 e53a622e2e86c0191677af3128e2a3b6 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 6.1E-29 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR86_02930 e53a622e2e86c0191677af3128e2a3b6 332 Pfam PF00107 Zinc-binding dehydrogenase 170 292 3.1E-14 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR86_02930 e53a622e2e86c0191677af3128e2a3b6 332 Gene3D G3DSA:3.40.50.720 146 281 1.3E-75 T 31-10-2018 DFR86_02930 e53a622e2e86c0191677af3128e2a3b6 332 SUPERFAMILY SSF50129 1 157 1.67E-42 T 31-10-2018 IPR011032 GroES-like superfamily DFR86_02930 e53a622e2e86c0191677af3128e2a3b6 332 Gene3D G3DSA:3.90.180.10 14 322 1.3E-75 T 31-10-2018 DFR86_01780 01ac53e25fc7fa238cac0f98d21b19fb 218 Gene3D G3DSA:3.60.21.10 1 217 1.3E-14 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR86_01780 01ac53e25fc7fa238cac0f98d21b19fb 218 SUPERFAMILY SSF56300 1 217 2.78E-24 T 31-10-2018 DFR86_01780 01ac53e25fc7fa238cac0f98d21b19fb 218 PIRSF PIRSF008292 1 218 1.8E-67 T 31-10-2018 IPR016538 Uncharacterised conserved protein UCP008292 DFR86_01780 01ac53e25fc7fa238cac0f98d21b19fb 218 Pfam PF00149 Calcineurin-like phosphoesterase 2 187 1.3E-14 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR86_07325 4aa7edba9b6564e7f111410248f2c05a 90 SUPERFAMILY SSF69695 10 88 5.23E-12 T 31-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 DFR86_07325 4aa7edba9b6564e7f111410248f2c05a 90 Gene3D G3DSA:3.30.56.30 1 90 3.2E-27 T 31-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 DFR86_00555 73b06acf4118369e4c971d0a0f996f13 523 Gene3D G3DSA:1.20.1730.10 39 520 2.1E-28 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily DFR86_00555 73b06acf4118369e4c971d0a0f996f13 523 Pfam PF00474 Sodium:solute symporter family 48 459 2.0E-7 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 DFR86_08280 d2942741c9d88fd220ea8128fef88e7a 281 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 276 3.3E-91 T 31-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 DFR86_08280 d2942741c9d88fd220ea8128fef88e7a 281 Gene3D G3DSA:3.30.470.80 171 280 9.7E-29 T 31-10-2018 DFR86_08280 d2942741c9d88fd220ea8128fef88e7a 281 Gene3D G3DSA:3.40.50.20 1 101 3.0E-29 T 31-10-2018 DFR86_08280 d2942741c9d88fd220ea8128fef88e7a 281 SUPERFAMILY SSF56059 85 277 1.1E-39 T 31-10-2018 DFR86_08280 d2942741c9d88fd220ea8128fef88e7a 281 Pfam PF08443 RimK-like ATP-grasp domain 84 276 3.1E-30 T 31-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 DFR86_08280 d2942741c9d88fd220ea8128fef88e7a 281 SUPERFAMILY SSF52440 2 86 2.3E-21 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR86_08280 d2942741c9d88fd220ea8128fef88e7a 281 Gene3D G3DSA:3.30.1490.20 102 170 1.1E-26 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_08280 d2942741c9d88fd220ea8128fef88e7a 281 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 3 278 1.2E-108 T 31-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 DFR86_04150 e9923e8f8cc2aeaa0f52338e904a2bfe 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.3E-15 T 31-10-2018 DFR86_04150 e9923e8f8cc2aeaa0f52338e904a2bfe 150 Gene3D G3DSA:3.30.70.920 53 150 1.3E-23 T 31-10-2018 DFR86_04150 e9923e8f8cc2aeaa0f52338e904a2bfe 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.6E-10 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_04150 e9923e8f8cc2aeaa0f52338e904a2bfe 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.6E-10 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_04150 e9923e8f8cc2aeaa0f52338e904a2bfe 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.6E-10 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_04150 e9923e8f8cc2aeaa0f52338e904a2bfe 150 Pfam PF01037 Lrp/AsnC ligand binding domain 75 139 5.8E-11 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR86_04150 e9923e8f8cc2aeaa0f52338e904a2bfe 150 Gene3D G3DSA:1.10.10.10 1 52 3.2E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_04150 e9923e8f8cc2aeaa0f52338e904a2bfe 150 SUPERFAMILY SSF54909 68 145 2.68E-12 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR86_04150 e9923e8f8cc2aeaa0f52338e904a2bfe 150 SMART SM00344 1 109 1.3E-27 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR86_04150 e9923e8f8cc2aeaa0f52338e904a2bfe 150 SUPERFAMILY SSF46785 1 59 7.86E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 395 36.626 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 Pfam PF00815 Histidinol dehydrogenase 12 394 2.1E-131 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 SUPERFAMILY SSF53720 15 391 8.04E-60 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 Gene3D G3DSA:3.40.50.1980 217 318 5.4E-101 T 31-10-2018 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 PIRSF PIRSF000099 1 396 8.0E-139 T 31-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 PRINTS PR00083 Histidinol dehydrogenase signature 154 180 3.6E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 PRINTS PR00083 Histidinol dehydrogenase signature 21 45 3.6E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 PRINTS PR00083 Histidinol dehydrogenase signature 184 209 3.6E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 PRINTS PR00083 Histidinol dehydrogenase signature 213 234 3.6E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 PRINTS PR00083 Histidinol dehydrogenase signature 330 348 3.6E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 PRINTS PR00083 Histidinol dehydrogenase signature 121 147 3.6E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 PRINTS PR00083 Histidinol dehydrogenase signature 290 315 3.6E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 PRINTS PR00083 Histidinol dehydrogenase signature 235 254 3.6E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 Gene3D G3DSA:3.40.50.1980 19 216 5.4E-101 T 31-10-2018 DFR86_08500 a3a56b0faefe8067566a3c5b66b7321e 396 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 21 394 1.6E-131 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR86_08210 a1d919918af09db86e76923218b08e9f 220 SMART SM00873 58 210 1.2E-23 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DFR86_08210 a1d919918af09db86e76923218b08e9f 220 Pfam PF03483 B3/4 domain 59 189 3.3E-29 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DFR86_08210 a1d919918af09db86e76923218b08e9f 220 Gene3D G3DSA:3.50.40.10 57 187 3.8E-11 T 31-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 DFR86_08210 a1d919918af09db86e76923218b08e9f 220 SUPERFAMILY SSF56037 46 218 5.1E-40 T 31-10-2018 DFR86_08940 a92016d4eb84166df8573da92186dc0b 714 SUPERFAMILY SSF51395 70 396 5.8E-91 T 31-10-2018 DFR86_08940 a92016d4eb84166df8573da92186dc0b 714 Pfam PF01645 Conserved region in glutamate synthase 60 378 1.5E-93 T 31-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 DFR86_08940 a92016d4eb84166df8573da92186dc0b 714 Gene3D G3DSA:3.20.20.70 421 686 2.2E-14 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_08940 a92016d4eb84166df8573da92186dc0b 714 SUPERFAMILY SSF51395 426 687 5.76E-24 T 31-10-2018 DFR86_08940 a92016d4eb84166df8573da92186dc0b 714 Pfam PF04898 Glutamate synthase central domain 428 488 8.6E-8 T 31-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 DFR86_08940 a92016d4eb84166df8573da92186dc0b 714 Pfam PF04898 Glutamate synthase central domain 590 684 7.6E-6 T 31-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 DFR86_08940 a92016d4eb84166df8573da92186dc0b 714 Gene3D G3DSA:3.20.20.70 23 416 2.7E-104 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_10570 88095ca4b0a77624e0a0d16fb05723d0 314 SMART SM00382 27 208 9.2E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_10570 88095ca4b0a77624e0a0d16fb05723d0 314 SUPERFAMILY SSF52540 3 238 1.73E-82 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_10570 88095ca4b0a77624e0a0d16fb05723d0 314 Pfam PF00005 ABC transporter 19 158 4.7E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_10570 88095ca4b0a77624e0a0d16fb05723d0 314 Gene3D G3DSA:3.40.50.300 1 235 5.6E-75 T 31-10-2018 DFR86_10570 88095ca4b0a77624e0a0d16fb05723d0 314 Pfam PF08402 TOBE domain 250 294 6.7E-5 T 31-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 DFR86_10570 88095ca4b0a77624e0a0d16fb05723d0 314 Gene3D G3DSA:2.40.50.140 253 308 3.5E-7 T 31-10-2018 DFR86_10570 88095ca4b0a77624e0a0d16fb05723d0 314 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_10570 88095ca4b0a77624e0a0d16fb05723d0 314 SUPERFAMILY SSF50331 240 308 5.44E-10 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal DFR86_06645 32a7f2a0e950bc2bdaf54585200dbb6f 230 PIRSF PIRSF004808 1 229 1.6E-57 T 31-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 DFR86_06645 32a7f2a0e950bc2bdaf54585200dbb6f 230 SUPERFAMILY SSF75217 2 157 7.33E-32 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases DFR86_06645 32a7f2a0e950bc2bdaf54585200dbb6f 230 Gene3D G3DSA:3.40.1280.10 1 155 9.7E-49 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DFR86_06645 32a7f2a0e950bc2bdaf54585200dbb6f 230 Pfam PF00588 SpoU rRNA Methylase family 2 150 4.5E-30 T 31-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 DFR86_09815 3a2b89b050aa7cc623c5d2649b34088f 542 Pfam PF04851 Type III restriction enzyme, res subunit 157 298 1.9E-19 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 DFR86_09815 3a2b89b050aa7cc623c5d2649b34088f 542 SUPERFAMILY SSF52540 199 522 1.55E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09815 3a2b89b050aa7cc623c5d2649b34088f 542 SMART SM00490 425 501 1.2E-15 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_09815 3a2b89b050aa7cc623c5d2649b34088f 542 SMART SM00487 155 336 2.1E-20 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_09815 3a2b89b050aa7cc623c5d2649b34088f 542 Gene3D G3DSA:3.40.50.300 323 541 2.7E-47 T 31-10-2018 DFR86_09815 3a2b89b050aa7cc623c5d2649b34088f 542 Gene3D G3DSA:3.40.50.300 147 322 1.0E-40 T 31-10-2018 DFR86_09815 3a2b89b050aa7cc623c5d2649b34088f 542 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 398 526 5.1E-24 T 31-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 DFR86_08075 5264dea3d11535545bfaad90d23f9c70 155 SUPERFAMILY SSF88802 2 66 9.81E-17 T 31-10-2018 DFR86_08075 5264dea3d11535545bfaad90d23f9c70 155 SUPERFAMILY SSF88697 74 152 1.66E-18 T 31-10-2018 IPR015947 PUA-like superfamily DFR86_08075 5264dea3d11535545bfaad90d23f9c70 155 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 3 152 7.5E-43 T 31-10-2018 IPR022430 Conserved hypothetical protein CHP03684 DFR86_08075 5264dea3d11535545bfaad90d23f9c70 155 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 46 148 4.3E-17 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 DFR86_08075 5264dea3d11535545bfaad90d23f9c70 155 Pfam PF09183 Domain of unknown function (DUF1947) 2 64 3.8E-21 T 31-10-2018 IPR015266 Domain of unknown function DUF1947 DFR86_08075 5264dea3d11535545bfaad90d23f9c70 155 PIRSF PIRSF005067 1 155 9.7E-37 T 31-10-2018 IPR016437 MCT-1/Tma20 DFR86_08075 5264dea3d11535545bfaad90d23f9c70 155 Gene3D G3DSA:3.10.450.120 1 66 1.6E-7 T 31-10-2018 DFR86_08075 5264dea3d11535545bfaad90d23f9c70 155 Gene3D G3DSA:2.30.130.10 71 154 1.8E-24 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 DFR86_08075 5264dea3d11535545bfaad90d23f9c70 155 SMART SM00359 73 147 5.2E-8 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR86_08075 5264dea3d11535545bfaad90d23f9c70 155 Pfam PF01472 PUA domain 75 144 3.3E-15 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR86_08570 3af11e81c130da6a21d15cae9b3d46f9 280 Gene3D G3DSA:1.20.120.1780 158 279 6.5E-5 T 31-10-2018 DFR86_08570 3af11e81c130da6a21d15cae9b3d46f9 280 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 1 274 21.019 T 31-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 DFR86_08570 3af11e81c130da6a21d15cae9b3d46f9 280 Pfam PF01040 UbiA prenyltransferase family 21 239 6.5E-42 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 DFR86_08570 3af11e81c130da6a21d15cae9b3d46f9 280 Gene3D G3DSA:1.10.357.140 7 157 4.6E-18 T 31-10-2018 DFR86_09900 7d28782adc4a1d157f99f54d2abb4555 376 Gene3D G3DSA:3.40.50.2000 185 361 4.4E-29 T 31-10-2018 DFR86_09900 7d28782adc4a1d157f99f54d2abb4555 376 Pfam PF00534 Glycosyl transferases group 1 203 358 1.2E-21 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR86_09900 7d28782adc4a1d157f99f54d2abb4555 376 SUPERFAMILY SSF53756 9 374 2.08E-38 T 31-10-2018 DFR86_03015 938f859b8487a07a1c82444fd9c67d94 172 Gene3D G3DSA:2.60.40.790 77 163 3.4E-23 T 31-10-2018 IPR008978 HSP20-like chaperone DFR86_03015 938f859b8487a07a1c82444fd9c67d94 172 Pfam PF00011 Hsp20/alpha crystallin family 88 171 9.3E-11 T 31-10-2018 IPR002068 Alpha crystallin/Hsp20 domain DFR86_03015 938f859b8487a07a1c82444fd9c67d94 172 SUPERFAMILY SSF49764 80 172 2.75E-22 T 31-10-2018 IPR008978 HSP20-like chaperone DFR86_07655 fee8d676a608cd8d95dd120862bd5abd 186 Pfam PF07185 Protein of unknown function (DUF1404) 15 181 1.5E-62 T 31-10-2018 IPR009844 Protein of unknown function DUF1404 DFR86_01285 95499840cb109feaa48c060e010b5fc7 185 Pfam PF07185 Protein of unknown function (DUF1404) 14 181 1.7E-48 T 31-10-2018 IPR009844 Protein of unknown function DUF1404 DFR86_02070 7f45697200229d00cdb08dc2a130c94f 309 Gene3D G3DSA:1.20.1260.10 1 137 1.6E-8 T 31-10-2018 IPR012347 Ferritin-like DFR86_02070 7f45697200229d00cdb08dc2a130c94f 309 SUPERFAMILY SSF47240 1 133 6.41E-17 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR86_02070 7f45697200229d00cdb08dc2a130c94f 309 Pfam PF02915 Rubrerythrin 3 133 1.2E-10 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 DFR86_02070 7f45697200229d00cdb08dc2a130c94f 309 Pfam PF01988 VIT family 143 223 1.3E-12 T 31-10-2018 IPR008217 Ccc1 family DFR86_02070 7f45697200229d00cdb08dc2a130c94f 309 Pfam PF01988 VIT family 227 301 1.4E-9 T 31-10-2018 IPR008217 Ccc1 family DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 8.8E-29 T 31-10-2018 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 8.8E-29 T 31-10-2018 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 8.8E-29 T 31-10-2018 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 8.8E-29 T 31-10-2018 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 8.8E-29 T 31-10-2018 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 SUPERFAMILY SSF51905 3 338 5.94E-38 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 Gene3D G3DSA:3.50.50.60 114 431 1.0E-130 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 SUPERFAMILY SSF55424 315 437 4.47E-27 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 2.7E-16 T 31-10-2018 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 2.7E-16 T 31-10-2018 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 276 2.7E-16 T 31-10-2018 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.7E-16 T 31-10-2018 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 Gene3D G3DSA:3.50.50.60 3 332 1.0E-130 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 299 2.1E-53 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_05170 dcdbed547d5d074186fea2aa4d8e7067 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 322 422 4.0E-16 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR86_05530 9085b4fbe32b0312479b31c98c2b606d 127 SUPERFAMILY SSF46785 23 119 4.23E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_05530 9085b4fbe32b0312479b31c98c2b606d 127 Gene3D G3DSA:1.10.10.10 17 121 4.7E-32 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_05530 9085b4fbe32b0312479b31c98c2b606d 127 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 25 99 1.4E-14 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 Gene3D G3DSA:3.30.260.10 153 411 3.1E-210 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 SUPERFAMILY SSF48592 24 531 4.01E-85 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 Gene3D G3DSA:1.10.560.10 35 528 3.1E-210 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 15 532 2.2E-243 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 SUPERFAMILY SSF52029 219 385 4.84E-60 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 380 402 1.6E-28 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 414 426 1.6E-28 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 96 115 1.6E-28 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 44 60 1.6E-28 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 66 84 1.6E-28 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 SUPERFAMILY SSF54849 155 412 6.41E-28 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 96 104 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 68 84 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 Gene3D G3DSA:3.50.7.10 224 375 3.1E-210 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 Pfam PF00118 TCP-1/cpn60 chaperonin family 43 533 1.5E-173 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 DFR86_06500 0bb62eb12a574e5092c5ce1cf20b701a 552 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 47 59 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR86_10150 2de7b7bfcde6eb6a91f79b6f9463889f 237 Pfam PF01048 Phosphorylase superfamily 16 233 1.9E-35 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DFR86_10150 2de7b7bfcde6eb6a91f79b6f9463889f 237 SUPERFAMILY SSF53167 4 235 3.53E-69 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 DFR86_10150 2de7b7bfcde6eb6a91f79b6f9463889f 237 Gene3D G3DSA:3.40.50.1580 1 236 2.9E-73 T 31-10-2018 DFR86_04365 8efae728fa9966bf720de152bcee97cf 341 Gene3D G3DSA:1.20.1250.20 1 155 7.6E-9 T 31-10-2018 DFR86_04365 8efae728fa9966bf720de152bcee97cf 341 Gene3D G3DSA:1.20.1250.20 165 340 8.7E-20 T 31-10-2018 DFR86_04365 8efae728fa9966bf720de152bcee97cf 341 Pfam PF07690 Major Facilitator Superfamily 170 339 2.9E-13 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_04365 8efae728fa9966bf720de152bcee97cf 341 SUPERFAMILY SSF103473 3 338 3.53E-32 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_03805 87c1d5882220f7e6b21c68373c8fe1d6 304 Pfam PF01206 Sulfurtransferase TusA 131 182 2.4E-8 T 31-10-2018 IPR001455 TusA-like domain DFR86_03805 87c1d5882220f7e6b21c68373c8fe1d6 304 SUPERFAMILY SSF64307 132 193 1.44E-9 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_03805 87c1d5882220f7e6b21c68373c8fe1d6 304 Gene3D G3DSA:3.30.110.40 127 195 3.0E-7 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_10700 367e3674447715d570273e70fe0bb6f0 171 SMART SM00746 121 157 8.2E-4 T 31-10-2018 IPR011017 TRASH domain DFR86_10700 367e3674447715d570273e70fe0bb6f0 171 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 48 1.5E-7 T 31-10-2018 DFR86_10700 367e3674447715d570273e70fe0bb6f0 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.9E-6 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_10700 367e3674447715d570273e70fe0bb6f0 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.9E-6 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_10700 367e3674447715d570273e70fe0bb6f0 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.9E-6 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_10700 367e3674447715d570273e70fe0bb6f0 171 Pfam PF08394 Archaeal TRASH domain 121 156 2.1E-15 T 31-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal DFR86_10700 367e3674447715d570273e70fe0bb6f0 171 SUPERFAMILY SSF46785 3 48 1.1E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_10700 367e3674447715d570273e70fe0bb6f0 171 Gene3D G3DSA:1.10.10.10 1 52 9.1E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_08140 8f1e38ce2a4ae71e1aaa3e5691b940ad 134 SUPERFAMILY SSF54631 6 129 3.79E-37 T 31-10-2018 DFR86_08140 8f1e38ce2a4ae71e1aaa3e5691b940ad 134 Gene3D G3DSA:3.10.580.10 2 131 9.8E-43 T 31-10-2018 DFR86_08140 8f1e38ce2a4ae71e1aaa3e5691b940ad 134 Pfam PF00571 CBS domain 70 124 4.6E-16 T 31-10-2018 IPR000644 CBS domain DFR86_08140 8f1e38ce2a4ae71e1aaa3e5691b940ad 134 Pfam PF00571 CBS domain 6 59 1.2E-15 T 31-10-2018 IPR000644 CBS domain DFR86_08140 8f1e38ce2a4ae71e1aaa3e5691b940ad 134 SMART SM00116 76 124 2.1E-11 T 31-10-2018 IPR000644 CBS domain DFR86_08140 8f1e38ce2a4ae71e1aaa3e5691b940ad 134 SMART SM00116 13 60 7.2E-12 T 31-10-2018 IPR000644 CBS domain DFR86_06025 3bad844a77ad4da1c7042feb349ed314 291 Gene3D G3DSA:3.60.110.10 2 258 9.0E-31 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR86_06025 3bad844a77ad4da1c7042feb349ed314 291 SUPERFAMILY SSF56317 9 244 6.41E-30 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR86_06025 3bad844a77ad4da1c7042feb349ed314 291 Pfam PF00795 Carbon-nitrogen hydrolase 11 250 9.9E-21 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 DFR86_02725 dc2459760d594f802fe0b8d18db76e75 362 SUPERFAMILY SSF50129 1 176 1.14E-58 T 31-10-2018 IPR011032 GroES-like superfamily DFR86_02725 dc2459760d594f802fe0b8d18db76e75 362 SMART SM00829 8 359 1.3E-7 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR86_02725 dc2459760d594f802fe0b8d18db76e75 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 149 2.8E-29 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR86_02725 dc2459760d594f802fe0b8d18db76e75 362 SUPERFAMILY SSF51735 155 326 5.52E-47 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_02725 dc2459760d594f802fe0b8d18db76e75 362 Gene3D G3DSA:3.90.180.10 5 356 2.2E-119 T 31-10-2018 DFR86_02725 dc2459760d594f802fe0b8d18db76e75 362 Pfam PF00107 Zinc-binding dehydrogenase 193 319 1.6E-29 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR86_02725 dc2459760d594f802fe0b8d18db76e75 362 SUPERFAMILY SSF50129 309 359 1.04E-5 T 31-10-2018 IPR011032 GroES-like superfamily DFR86_02725 dc2459760d594f802fe0b8d18db76e75 362 Gene3D G3DSA:3.40.50.720 171 306 2.2E-119 T 31-10-2018 DFR86_02725 dc2459760d594f802fe0b8d18db76e75 362 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 45 56 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 Gene3D G3DSA:3.10.580.10 213 311 5.4E-11 T 31-10-2018 DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 Gene3D G3DSA:3.30.70.20 2 78 1.2E-9 T 31-10-2018 DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 SUPERFAMILY SSF54631 136 265 4.87E-19 T 31-10-2018 DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 Pfam PF00571 CBS domain 80 132 2.3E-5 T 31-10-2018 IPR000644 CBS domain DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 Pfam PF00571 CBS domain 220 262 9.0E-6 T 31-10-2018 IPR000644 CBS domain DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 Pfam PF00571 CBS domain 147 192 6.5E-8 T 31-10-2018 IPR000644 CBS domain DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 Pfam PF13237 4Fe-4S dicluster domain 5 56 4.2E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 SMART SM00116 218 263 1.1 T 31-10-2018 IPR000644 CBS domain DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 SMART SM00116 145 193 6.0E-4 T 31-10-2018 IPR000644 CBS domain DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 SMART SM00116 87 133 11.0 T 31-10-2018 IPR000644 CBS domain DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 Gene3D G3DSA:3.10.580.10 79 204 5.9E-20 T 31-10-2018 DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 SUPERFAMILY SSF54631 29 138 2.21E-6 T 31-10-2018 DFR86_04550 3748602fa2822058c2dd1f455ad01431 330 SUPERFAMILY SSF54862 3 71 6.8E-16 T 31-10-2018 DFR86_02955 dadea48b08e867a2f6609546e7f05deb 273 SUPERFAMILY SSF53697 21 219 3.48E-24 T 31-10-2018 DFR86_02955 dadea48b08e867a2f6609546e7f05deb 273 Gene3D G3DSA:3.40.50.10490 147 249 1.0E-7 T 31-10-2018 DFR86_02955 dadea48b08e867a2f6609546e7f05deb 273 Pfam PF01380 SIS domain 25 134 5.4E-7 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR86_02955 dadea48b08e867a2f6609546e7f05deb 273 Gene3D G3DSA:3.40.50.10490 1 146 1.1E-13 T 31-10-2018 DFR86_06405 d1ae9d62404833d91f6764de75c604f1 173 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 56 162 7.0E-26 T 31-10-2018 IPR002802 Protein of unknown function DUF99 DFR86_06405 d1ae9d62404833d91f6764de75c604f1 173 PIRSF PIRSF006380 1 171 1.3E-39 T 31-10-2018 IPR002802 Protein of unknown function DUF99 DFR86_06405 d1ae9d62404833d91f6764de75c604f1 173 Pfam PF01949 Protein of unknown function DUF99 3 165 1.3E-19 T 31-10-2018 IPR002802 Protein of unknown function DUF99 DFR86_06405 d1ae9d62404833d91f6764de75c604f1 173 Hamap MF_00582 UPF0215 protein . 1 167 21.518 T 31-10-2018 IPR002802 Protein of unknown function DUF99 DFR86_06405 d1ae9d62404833d91f6764de75c604f1 173 Gene3D G3DSA:3.30.2170.10 2 170 3.1E-18 T 31-10-2018 DFR86_07660 a88919d3ad0fca8620b3a1c0c558417b 520 Gene3D G3DSA:1.20.1740.10 15 516 3.3E-9 T 31-10-2018 DFR86_07660 a88919d3ad0fca8620b3a1c0c558417b 520 Pfam PF13520 Amino acid permease 20 484 2.7E-20 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_07660 a88919d3ad0fca8620b3a1c0c558417b 520 PIRSF PIRSF006060 1 519 6.3E-40 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_01545 bddd4d5706b78598ce20663e02548958 506 Gene3D G3DSA:2.40.110.10 147 275 1.5E-40 T 31-10-2018 DFR86_01545 bddd4d5706b78598ce20663e02548958 506 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 282 477 5.7E-64 T 31-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal DFR86_01545 bddd4d5706b78598ce20663e02548958 506 SUPERFAMILY SSF56645 3 274 6.15E-75 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR86_01545 bddd4d5706b78598ce20663e02548958 506 Gene3D G3DSA:1.20.140.10 278 479 2.0E-73 T 31-10-2018 DFR86_01545 bddd4d5706b78598ce20663e02548958 506 SUPERFAMILY SSF47203 265 478 1.32E-64 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR86_01545 bddd4d5706b78598ce20663e02548958 506 PIRSF PIRSF000331 1 488 1.6E-161 T 31-10-2018 IPR004925 HpaB/PvcC/4-BUDH DFR86_01545 bddd4d5706b78598ce20663e02548958 506 Gene3D G3DSA:1.10.3140.10 2 145 4.3E-42 T 31-10-2018 DFR86_01545 bddd4d5706b78598ce20663e02548958 506 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 274 3.2E-90 T 31-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 Gene3D G3DSA:1.20.210.10 24 527 1.4E-67 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 203 222 3.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 384 403 3.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 319 340 3.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 75 98 3.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 295 310 3.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 356 374 3.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 PRINTS PR01165 Cytochrome c oxidase subunit I signature 249 270 3.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 251 305 - T 31-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 SUPERFAMILY SSF81442 35 499 5.36E-79 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01295 7a19a0c1dafe2d49d04c60402ab0425f 557 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 39 476 1.5E-68 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_10755 0ce97609ca65bf44169ddfcd7a98f05c 79 SUPERFAMILY SSF64307 1 77 3.53E-24 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_10755 0ce97609ca65bf44169ddfcd7a98f05c 79 Pfam PF01206 Sulfurtransferase TusA 8 77 1.4E-22 T 31-10-2018 IPR001455 TusA-like domain DFR86_10755 0ce97609ca65bf44169ddfcd7a98f05c 79 Gene3D G3DSA:3.30.110.40 2 79 1.3E-29 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_10755 0ce97609ca65bf44169ddfcd7a98f05c 79 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 10 34 - T 31-10-2018 IPR001455 TusA-like domain DFR86_05345 af94e07451ec26306ae408ec61ca992f 178 Gene3D G3DSA:1.20.58.2050 42 173 1.3E-5 T 31-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 DFR86_05345 af94e07451ec26306ae408ec61ca992f 178 Pfam PF05916 GINS complex protein 45 155 2.1E-8 T 31-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 DFR86_11320 7a286c01600f0ede8abdf7c750977bb5 412 Gene3D G3DSA:3.50.50.60 1 411 4.2E-52 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_11320 7a286c01600f0ede8abdf7c750977bb5 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 366 388 1.3E-5 T 31-10-2018 DFR86_11320 7a286c01600f0ede8abdf7c750977bb5 412 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.3E-5 T 31-10-2018 DFR86_11320 7a286c01600f0ede8abdf7c750977bb5 412 SUPERFAMILY SSF54373 188 285 8.63E-8 T 31-10-2018 DFR86_11320 7a286c01600f0ede8abdf7c750977bb5 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 3.3E-8 T 31-10-2018 DFR86_11320 7a286c01600f0ede8abdf7c750977bb5 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.3E-8 T 31-10-2018 DFR86_11320 7a286c01600f0ede8abdf7c750977bb5 412 Pfam PF03486 HI0933-like protein 3 40 5.3E-6 T 31-10-2018 DFR86_11320 7a286c01600f0ede8abdf7c750977bb5 412 SUPERFAMILY SSF51905 1 339 9.35E-28 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_08200 6bb1d47e80911458713fbca363e88ccc 447 SUPERFAMILY SSF111283 7 439 5.89E-83 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 DFR86_08200 6bb1d47e80911458713fbca363e88ccc 447 PIRSF PIRSF004919 1 447 1.0E-131 T 31-10-2018 IPR025502 TldD DFR86_08200 6bb1d47e80911458713fbca363e88ccc 447 Pfam PF01523 Putative modulator of DNA gyrase 15 301 3.0E-40 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 DFR86_08200 6bb1d47e80911458713fbca363e88ccc 447 Gene3D G3DSA:3.30.2290.10 1 185 4.9E-7 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal DFR86_09775 e956f524c24ad6d6655499a2c9735a5f 254 Gene3D G3DSA:3.30.950.10 116 254 7.9E-36 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 DFR86_09775 e956f524c24ad6d6655499a2c9735a5f 254 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 223 1.9E-20 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR86_09775 e956f524c24ad6d6655499a2c9735a5f 254 PIRSF PIRSF036432 3 254 1.3E-81 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 DFR86_09775 e956f524c24ad6d6655499a2c9735a5f 254 Gene3D G3DSA:3.40.1010.10 1 114 1.4E-27 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR86_09775 e956f524c24ad6d6655499a2c9735a5f 254 SUPERFAMILY SSF53790 4 249 3.66E-49 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR86_09775 e956f524c24ad6d6655499a2c9735a5f 254 Hamap MF_01084 Diphthine synthase [dphB]. 3 254 27.742 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 DFR86_09775 e956f524c24ad6d6655499a2c9735a5f 254 TIGRFAM TIGR00522 dph5: diphthine synthase 4 252 2.1E-55 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SUPERFAMILY SSF48403 365 644 1.13E-84 T 31-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Gene3D G3DSA:1.25.40.20 560 646 3.1E-35 T 31-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SUPERFAMILY SSF48403 4 281 2.73E-71 T 31-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Gene3D G3DSA:1.25.40.20 104 185 1.5E-24 T 31-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Gene3D G3DSA:1.25.40.20 1 103 7.9E-38 T 31-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Gene3D G3DSA:1.25.40.20 345 441 7.6E-32 T 31-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 372 401 1.6E-8 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 272 301 2400.0 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 522 551 5.3E-7 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 555 584 3.9E-7 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 621 646 650.0 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 239 268 4.0E-8 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 98 127 4.0E-7 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 438 467 5.1E-10 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 489 518 2.2E-7 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 405 434 6.3E-8 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 131 160 1.2E-4 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 588 617 5.6E-9 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 32 61 4.4E-7 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 SMART SM00248 65 94 6.6E-7 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Gene3D G3DSA:1.25.40.20 228 296 1.8E-15 T 31-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Pfam PF12796 Ankyrin repeats (3 copies) 524 586 6.1E-16 T 31-10-2018 IPR020683 Ankyrin repeat-containing domain DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Pfam PF12796 Ankyrin repeats (3 copies) 6 96 3.6E-18 T 31-10-2018 IPR020683 Ankyrin repeat-containing domain DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Pfam PF12796 Ankyrin repeats (3 copies) 359 403 3.2E-8 T 31-10-2018 IPR020683 Ankyrin repeat-containing domain DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Pfam PF12796 Ankyrin repeats (3 copies) 232 293 3.4E-10 T 31-10-2018 IPR020683 Ankyrin repeat-containing domain DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Pfam PF12796 Ankyrin repeats (3 copies) 405 469 2.8E-19 T 31-10-2018 IPR020683 Ankyrin repeat-containing domain DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Pfam PF12796 Ankyrin repeats (3 copies) 98 162 3.3E-15 T 31-10-2018 IPR020683 Ankyrin repeat-containing domain DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Pfam PF12796 Ankyrin repeats (3 copies) 588 641 2.8E-13 T 31-10-2018 IPR020683 Ankyrin repeat-containing domain DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Pfam PF12796 Ankyrin repeats (3 copies) 478 520 3.4E-7 T 31-10-2018 IPR020683 Ankyrin repeat-containing domain DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Gene3D G3DSA:1.25.40.960 442 474 3.2E-11 T 31-10-2018 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Gene3D G3DSA:1.25.40.960 488 526 4.8E-14 T 31-10-2018 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 Gene3D G3DSA:1.25.40.960 527 559 8.4E-14 T 31-10-2018 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 PRINTS PR01415 Ankyrin repeat signature 388 402 3.6E-10 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_11675 5510ef8f26b9b9a8587229467db921e3 646 PRINTS PR01415 Ankyrin repeat signature 240 255 3.6E-10 T 31-10-2018 IPR002110 Ankyrin repeat GO:0005515 DFR86_05165 2bfe219f6acd20a3d7ca534921fd8c56 359 Pfam PF09376 NurA domain 53 329 1.1E-19 T 31-10-2018 IPR018977 NurA domain DFR86_05165 2bfe219f6acd20a3d7ca534921fd8c56 359 SMART SM00933 52 330 2.6E-16 T 31-10-2018 IPR018977 NurA domain DFR86_05835 b9a38f9fdf4b3720f2c50708bccc32d7 154 SUPERFAMILY SSF55729 3 146 3.06E-29 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR86_05835 b9a38f9fdf4b3720f2c50708bccc32d7 154 Pfam PF00583 Acetyltransferase (GNAT) family 13 119 5.0E-17 T 31-10-2018 IPR000182 GNAT domain DFR86_05835 b9a38f9fdf4b3720f2c50708bccc32d7 154 Gene3D G3DSA:3.40.630.30 1 150 6.6E-33 T 31-10-2018 DFR86_00635 2e03ce00d96045884dd47516ff70b7a4 453 Pfam PF01593 Flavin containing amine oxidoreductase 10 448 2.7E-16 T 31-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 DFR86_00635 2e03ce00d96045884dd47516ff70b7a4 453 Gene3D G3DSA:3.50.50.60 149 313 1.1E-10 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_00635 2e03ce00d96045884dd47516ff70b7a4 453 Gene3D G3DSA:3.50.50.60 1 89 1.5E-17 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_00635 2e03ce00d96045884dd47516ff70b7a4 453 SUPERFAMILY SSF51905 1 451 4.66E-45 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_00635 2e03ce00d96045884dd47516ff70b7a4 453 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 3 451 4.8E-84 T 31-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 DFR86_00645 1ae2312f7e2690812ba46c0a23e221e0 278 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 147 172 - T 31-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 DFR86_00645 1ae2312f7e2690812ba46c0a23e221e0 278 SUPERFAMILY SSF48576 6 270 1.24E-57 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR86_00645 1ae2312f7e2690812ba46c0a23e221e0 278 Pfam PF00494 Squalene/phytoene synthase 10 252 3.8E-43 T 31-10-2018 DFR86_00645 1ae2312f7e2690812ba46c0a23e221e0 278 Gene3D G3DSA:1.10.600.10 1 265 3.7E-54 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR86_06570 f29c74099ecae463db4502d2eea63c76 319 Gene3D G3DSA:3.40.50.150 6 310 1.5E-67 T 31-10-2018 DFR86_06570 f29c74099ecae463db4502d2eea63c76 319 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 5 210 6.3E-37 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR86_06570 f29c74099ecae463db4502d2eea63c76 319 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 4 20 1.0E-13 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR86_06570 f29c74099ecae463db4502d2eea63c76 319 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 118 132 1.0E-13 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR86_06570 f29c74099ecae463db4502d2eea63c76 319 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 163 176 1.0E-13 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR86_06570 f29c74099ecae463db4502d2eea63c76 319 SUPERFAMILY SSF53335 3 312 1.88E-75 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_06570 f29c74099ecae463db4502d2eea63c76 319 Pfam PF00145 C-5 cytosine-specific DNA methylase 3 214 7.1E-39 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR86_06570 f29c74099ecae463db4502d2eea63c76 319 Pfam PF00145 C-5 cytosine-specific DNA methylase 255 312 3.2E-11 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR86_06570 f29c74099ecae463db4502d2eea63c76 319 Gene3D G3DSA:3.90.120.10 158 303 1.5E-67 T 31-10-2018 DFR86_08780 4530d8dc5150c5536247fb1a294fed67 227 Pfam PF13938 Putative heavy-metal chelation 9 83 2.7E-11 T 31-10-2018 IPR025251 Domain of unknown function DUF4213 DFR86_08780 4530d8dc5150c5536247fb1a294fed67 227 SUPERFAMILY SSF159713 1 224 7.19E-34 T 31-10-2018 DFR86_08780 4530d8dc5150c5536247fb1a294fed67 227 Pfam PF04016 Putative heavy-metal chelation 93 225 2.4E-21 T 31-10-2018 IPR007161 Putative heavy-metal chelation domain DFR86_04835 3bdf4d27511a25e0d17ed99ce6c80a2a 370 Gene3D G3DSA:3.90.1150.10 260 360 5.0E-43 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_04835 3bdf4d27511a25e0d17ed99ce6c80a2a 370 SUPERFAMILY SSF53383 16 365 2.42E-40 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_04835 3bdf4d27511a25e0d17ed99ce6c80a2a 370 Gene3D G3DSA:3.90.1150.10 20 52 3.1E-11 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_04835 3bdf4d27511a25e0d17ed99ce6c80a2a 370 Pfam PF00202 Aminotransferase class-III 134 303 2.2E-18 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_04835 3bdf4d27511a25e0d17ed99ce6c80a2a 370 Gene3D G3DSA:3.40.640.10 53 116 3.1E-11 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_04835 3bdf4d27511a25e0d17ed99ce6c80a2a 370 Gene3D G3DSA:3.40.640.10 127 259 5.0E-43 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 SMART SM00663 205 510 7.2E-205 T 31-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Pfam PF04983 RNA polymerase Rpb1, domain 3 485 651 2.2E-35 T 31-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Gene3D G3DSA:3.30.1490.180 348 413 9.4E-83 T 31-10-2018 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Gene3D G3DSA:1.10.132.30 648 791 1.1E-47 T 31-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Pfam PF00623 RNA polymerase Rpb1, domain 2 315 482 1.0E-74 T 31-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Pfam PF04997 RNA polymerase Rpb1, domain 1 4 313 9.4E-100 T 31-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Gene3D G3DSA:1.10.10.1950 602 647 2.0E-13 T 31-10-2018 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Gene3D G3DSA:1.10.10.1950 483 553 1.5E-12 T 31-10-2018 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 SUPERFAMILY SSF64484 4 865 0.0 T 31-10-2018 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Gene3D G3DSA:2.20.25.410 828 880 2.4E-23 T 31-10-2018 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Gene3D G3DSA:1.20.120.1280 229 278 2.4E-11 T 31-10-2018 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Gene3D G3DSA:1.20.120.1280 1 111 4.1E-29 T 31-10-2018 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Gene3D G3DSA:2.40.40.20 305 477 9.4E-83 T 31-10-2018 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Pfam PF04998 RNA polymerase Rpb1, domain 5 789 854 3.5E-23 T 31-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Gene3D G3DSA:2.60.40.2940 555 601 1.6E-25 T 31-10-2018 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 Pfam PF05000 RNA polymerase Rpb1, domain 4 678 782 5.8E-33 T 31-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06240 249ee909e57baab7045d3891f21f3247 880 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 4 872 0.0 T 31-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_08150 5a40db4f43f422fb8eaef48503260ad8 296 Gene3D G3DSA:3.30.420.40 106 273 1.4E-93 T 31-10-2018 DFR86_08150 5a40db4f43f422fb8eaef48503260ad8 296 SUPERFAMILY SSF53067 1 104 2.36E-18 T 31-10-2018 DFR86_08150 5a40db4f43f422fb8eaef48503260ad8 296 Gene3D G3DSA:3.30.420.40 4 285 1.4E-93 T 31-10-2018 DFR86_08150 5a40db4f43f422fb8eaef48503260ad8 296 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 283 5.1E-43 T 31-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 DFR86_08150 5a40db4f43f422fb8eaef48503260ad8 296 SUPERFAMILY SSF53067 107 290 3.53E-44 T 31-10-2018 DFR86_07905 ba2d7772ef2cde18eb2f31f150613467 184 Gene3D G3DSA:3.40.1050.10 1 131 1.6E-9 T 31-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 DFR86_07905 ba2d7772ef2cde18eb2f31f150613467 184 SUPERFAMILY SSF53056 4 127 3.92E-13 T 31-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 DFR86_06010 103719a504be2d3113d7252f9437ad26 48 Gene3D G3DSA:1.10.1220.10 8 45 1.4E-9 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DFR86_06010 103719a504be2d3113d7252f9437ad26 48 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 40 2.5E-9 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR86_06010 103719a504be2d3113d7252f9437ad26 48 SUPERFAMILY SSF47598 1 46 1.11E-12 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR86_02420 9bd1d28e9b4a748331b3bfb0a80a6325 150 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 31-10-2018 IPR019808 Histidine triad, conserved site DFR86_02420 9bd1d28e9b4a748331b3bfb0a80a6325 150 Pfam PF01230 HIT domain 12 105 9.7E-25 T 31-10-2018 IPR001310 Histidine triad (HIT) protein DFR86_02420 9bd1d28e9b4a748331b3bfb0a80a6325 150 SUPERFAMILY SSF54197 3 135 7.66E-39 T 31-10-2018 IPR036265 HIT-like superfamily DFR86_02420 9bd1d28e9b4a748331b3bfb0a80a6325 150 Gene3D G3DSA:3.30.428.10 4 149 4.5E-43 T 31-10-2018 IPR036265 HIT-like superfamily DFR86_02420 9bd1d28e9b4a748331b3bfb0a80a6325 150 PRINTS PR00332 Histidine triad family signature 93 103 1.4E-13 T 31-10-2018 IPR001310 Histidine triad (HIT) protein DFR86_02420 9bd1d28e9b4a748331b3bfb0a80a6325 150 PRINTS PR00332 Histidine triad family signature 5 21 1.4E-13 T 31-10-2018 IPR001310 Histidine triad (HIT) protein DFR86_02420 9bd1d28e9b4a748331b3bfb0a80a6325 150 PRINTS PR00332 Histidine triad family signature 26 44 1.4E-13 T 31-10-2018 IPR001310 Histidine triad (HIT) protein DFR86_10005 d7b748e1929bcd90e35efe3112e3f455 385 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 136 4.0E-32 T 31-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 DFR86_10005 d7b748e1929bcd90e35efe3112e3f455 385 Gene3D G3DSA:3.40.50.800 272 380 4.0E-27 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily DFR86_10005 d7b748e1929bcd90e35efe3112e3f455 385 SUPERFAMILY SSF52954 272 371 3.02E-26 T 31-10-2018 DFR86_10005 d7b748e1929bcd90e35efe3112e3f455 385 Gene3D G3DSA:3.50.80.10 1 136 1.2E-47 T 31-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily DFR86_10005 d7b748e1929bcd90e35efe3112e3f455 385 Pfam PF03129 Anticodon binding domain 281 370 2.4E-22 T 31-10-2018 IPR004154 Anticodon-binding DFR86_10005 d7b748e1929bcd90e35efe3112e3f455 385 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 136 5.3E-50 T 31-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 DFR86_03790 3b3489c680a0a58f0e1d32da4622910c 305 Pfam PF07859 alpha/beta hydrolase fold 74 279 2.9E-69 T 31-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 DFR86_03790 3b3489c680a0a58f0e1d32da4622910c 305 Gene3D G3DSA:3.40.50.1820 15 303 5.9E-89 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_03790 3b3489c680a0a58f0e1d32da4622910c 305 SUPERFAMILY SSF53474 41 301 3.65E-69 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_02210 7cd66a5ad3ab6949098c3a7e33726d4d 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.0E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_02210 7cd66a5ad3ab6949098c3a7e33726d4d 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 7.0E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_02210 7cd66a5ad3ab6949098c3a7e33726d4d 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 7.0E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_02210 7cd66a5ad3ab6949098c3a7e33726d4d 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 7.0E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_02210 7cd66a5ad3ab6949098c3a7e33726d4d 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 235 4.2E-28 T 31-10-2018 DFR86_02210 7cd66a5ad3ab6949098c3a7e33726d4d 239 SUPERFAMILY SSF51735 4 236 3.05E-44 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_02210 7cd66a5ad3ab6949098c3a7e33726d4d 239 Gene3D G3DSA:3.40.50.720 1 238 2.1E-42 T 31-10-2018 DFR86_04110 f9d335ff3b39b984b0b0205b4e1a0bf5 571 Gene3D G3DSA:1.20.1250.20 283 466 2.5E-16 T 31-10-2018 DFR86_04110 f9d335ff3b39b984b0b0205b4e1a0bf5 571 SUPERFAMILY SSF103473 4 445 4.84E-50 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_04110 f9d335ff3b39b984b0b0205b4e1a0bf5 571 Pfam PF07690 Major Facilitator Superfamily 14 425 1.4E-41 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_04110 f9d335ff3b39b984b0b0205b4e1a0bf5 571 Gene3D G3DSA:1.20.1250.20 7 230 1.1E-30 T 31-10-2018 DFR86_07895 d2beff1c802a275db16c4e4befc9145e 391 Pfam PF07690 Major Facilitator Superfamily 14 291 1.8E-17 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_07895 d2beff1c802a275db16c4e4befc9145e 391 Gene3D G3DSA:1.20.1250.20 4 192 1.4E-13 T 31-10-2018 DFR86_07895 d2beff1c802a275db16c4e4befc9145e 391 Gene3D G3DSA:1.20.1250.20 195 389 1.5E-16 T 31-10-2018 DFR86_07895 d2beff1c802a275db16c4e4befc9145e 391 SUPERFAMILY SSF103473 11 386 8.63E-42 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_03620 804a013dcc017d8adb92104b3ef6e277 573 SUPERFAMILY SSF48208 182 568 7.59E-86 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR86_03620 804a013dcc017d8adb92104b3ef6e277 573 Gene3D G3DSA:1.50.10.10 208 572 2.0E-78 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR86_03620 804a013dcc017d8adb92104b3ef6e277 573 Pfam PF00723 Glycosyl hydrolases family 15 209 513 1.1E-48 T 31-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 DFR86_10070 b18cf3241418b885b95d1ea8c7502dbd 437 SUPERFAMILY SSF53756 105 432 1.61E-54 T 31-10-2018 DFR86_10070 b18cf3241418b885b95d1ea8c7502dbd 437 Pfam PF00534 Glycosyl transferases group 1 238 408 1.2E-32 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR86_10070 b18cf3241418b885b95d1ea8c7502dbd 437 Gene3D G3DSA:3.40.50.2000 231 415 1.4E-41 T 31-10-2018 DFR86_10070 b18cf3241418b885b95d1ea8c7502dbd 437 Gene3D G3DSA:3.40.50.2000 30 230 3.0E-6 T 31-10-2018 DFR86_06795 5725191e1d3ac880e45be4aa3bbb3fff 156 Pfam PF00237 Ribosomal protein L22p/L17e 20 153 1.9E-31 T 31-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 DFR86_06795 5725191e1d3ac880e45be4aa3bbb3fff 156 Gene3D G3DSA:3.90.470.10 5 156 6.0E-50 T 31-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_06795 5725191e1d3ac880e45be4aa3bbb3fff 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 129 153 - T 31-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06795 5725191e1d3ac880e45be4aa3bbb3fff 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 10 156 2.2E-50 T 31-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06795 5725191e1d3ac880e45be4aa3bbb3fff 156 SUPERFAMILY SSF54843 8 156 1.7E-47 T 31-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_06795 5725191e1d3ac880e45be4aa3bbb3fff 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 2 156 31.683 T 31-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_07960 d29d83d3aae3f144a72ce5702a0f9337 438 Pfam PF00324 Amino acid permease 25 404 2.5E-13 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR86_07960 d29d83d3aae3f144a72ce5702a0f9337 438 PIRSF PIRSF006060 1 438 2.2E-37 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_07960 d29d83d3aae3f144a72ce5702a0f9337 438 Gene3D G3DSA:1.20.1740.10 12 436 2.6E-19 T 31-10-2018 DFR86_05775 603ccce5db675a3738389fc863433bf2 147 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 5 143 1.7E-42 T 31-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 DFR86_05775 603ccce5db675a3738389fc863433bf2 147 PIRSF PIRSF002181 1 146 2.1E-35 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 DFR86_05775 603ccce5db675a3738389fc863433bf2 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 4 134 18.272 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 DFR86_05775 603ccce5db675a3738389fc863433bf2 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 83 105 - T 31-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 DFR86_05775 603ccce5db675a3738389fc863433bf2 147 Gene3D G3DSA:3.90.1180.10 1 144 2.2E-43 T 31-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_05775 603ccce5db675a3738389fc863433bf2 147 SUPERFAMILY SSF52161 4 144 7.19E-36 T 31-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 DFR86_05775 603ccce5db675a3738389fc863433bf2 147 Pfam PF00572 Ribosomal protein L13 6 107 1.2E-7 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 DFR86_00410 440c034a07a1eebb33241ddeab4f6c62 989 SMART SM00490 528 606 2.3E-15 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_00410 440c034a07a1eebb33241ddeab4f6c62 989 Pfam PF00270 DEAD/DEAH box helicase 160 247 2.1E-11 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_00410 440c034a07a1eebb33241ddeab4f6c62 989 Pfam PF00271 Helicase conserved C-terminal domain 530 605 2.7E-14 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_00410 440c034a07a1eebb33241ddeab4f6c62 989 SMART SM00487 153 424 1.9E-15 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_00410 440c034a07a1eebb33241ddeab4f6c62 989 SUPERFAMILY SSF52540 165 608 5.13E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08080 7feb647cf55b16dbe021dbf5aedb16bc 710 SMART SM01008 18 107 4.0E-31 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_08080 7feb647cf55b16dbe021dbf5aedb16bc 710 Gene3D G3DSA:3.30.365.10 161 253 9.2E-66 T 31-10-2018 DFR86_08080 7feb647cf55b16dbe021dbf5aedb16bc 710 SUPERFAMILY SSF54665 2 112 1.28E-31 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR86_08080 7feb647cf55b16dbe021dbf5aedb16bc 710 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 126 655 5.1E-149 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR86_08080 7feb647cf55b16dbe021dbf5aedb16bc 710 Gene3D G3DSA:3.30.365.10 341 694 2.0E-108 T 31-10-2018 DFR86_08080 7feb647cf55b16dbe021dbf5aedb16bc 710 SUPERFAMILY SSF56003 99 707 1.06E-166 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR86_08080 7feb647cf55b16dbe021dbf5aedb16bc 710 Gene3D G3DSA:3.90.1170.50 2 106 2.6E-40 T 31-10-2018 DFR86_08080 7feb647cf55b16dbe021dbf5aedb16bc 710 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 107 3.7E-15 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_08080 7feb647cf55b16dbe021dbf5aedb16bc 710 Gene3D G3DSA:3.30.365.10 121 332 9.2E-66 T 31-10-2018 DFR86_08080 7feb647cf55b16dbe021dbf5aedb16bc 710 Gene3D G3DSA:3.30.365.10 421 570 2.0E-108 T 31-10-2018 DFR86_06790 2c333ea8bec10f68a0bb49da6d0e70a6 140 PRINTS PR00975 Ribosomal protein S19 family signature 104 119 8.1E-14 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06790 2c333ea8bec10f68a0bb49da6d0e70a6 140 PRINTS PR00975 Ribosomal protein S19 family signature 72 91 8.1E-14 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06790 2c333ea8bec10f68a0bb49da6d0e70a6 140 PRINTS PR00975 Ribosomal protein S19 family signature 92 104 8.1E-14 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06790 2c333ea8bec10f68a0bb49da6d0e70a6 140 Pfam PF00203 Ribosomal protein S19 40 122 3.1E-32 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06790 2c333ea8bec10f68a0bb49da6d0e70a6 140 PIRSF PIRSF002144 2 139 2.0E-37 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06790 2c333ea8bec10f68a0bb49da6d0e70a6 140 Gene3D G3DSA:3.30.860.20 7 139 3.9E-51 T 31-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06790 2c333ea8bec10f68a0bb49da6d0e70a6 140 ProSitePatterns PS00323 Ribosomal protein S19 signature. 92 116 - T 31-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06790 2c333ea8bec10f68a0bb49da6d0e70a6 140 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 38 128 23.415 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06790 2c333ea8bec10f68a0bb49da6d0e70a6 140 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 10 139 1.3E-59 T 31-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06790 2c333ea8bec10f68a0bb49da6d0e70a6 140 SUPERFAMILY SSF54570 40 123 2.62E-25 T 31-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 Pfam PF01300 Telomere recombination 211 386 3.8E-46 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 SUPERFAMILY SSF54975 3 89 7.85E-23 T 31-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 Pfam PF07503 HypF finger 158 191 3.1E-13 T 31-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 Pfam PF07503 HypF finger 107 141 5.1E-13 T 31-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 Gene3D G3DSA:3.30.110.120 254 373 1.6E-130 T 31-10-2018 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 Gene3D G3DSA:3.90.870.50 6 364 1.6E-130 T 31-10-2018 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 Gene3D G3DSA:3.30.420.350 489 726 1.9E-94 T 31-10-2018 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 PIRSF PIRSF006256 1 742 4.3E-244 T 31-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 Pfam PF00708 Acylphosphatase 5 88 3.3E-20 T 31-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 SUPERFAMILY SSF55821 177 392 2.41E-42 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 Gene3D G3DSA:3.30.420.360 385 737 1.9E-94 T 31-10-2018 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 7 738 5.9E-231 T 31-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR86_03960 b8ab4f6a4e37c9e10a85bb6d62c664c7 743 SUPERFAMILY SSF53067 438 723 4.1E-5 T 31-10-2018 DFR86_02140 7247ebd436931b97baf160a0131da51a 537 Gene3D G3DSA:1.20.210.10 13 519 1.2E-84 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_02140 7247ebd436931b97baf160a0131da51a 537 SUPERFAMILY SSF81442 25 493 7.06E-92 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_02140 7247ebd436931b97baf160a0131da51a 537 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 471 2.7E-76 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_02140 7247ebd436931b97baf160a0131da51a 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 427 448 3.1E-10 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_02140 7247ebd436931b97baf160a0131da51a 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 264 3.1E-10 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_02140 7247ebd436931b97baf160a0131da51a 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 140 152 3.1E-10 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_02140 7247ebd436931b97baf160a0131da51a 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 66 89 3.1E-10 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_02140 7247ebd436931b97baf160a0131da51a 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 313 334 3.1E-10 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_02140 7247ebd436931b97baf160a0131da51a 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 3.1E-10 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_05785 4b540cde63c4ae445991af3244385582 261 SUPERFAMILY SSF55257 2 259 2.16E-24 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_05785 4b540cde63c4ae445991af3244385582 261 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 1 261 29.157 T 31-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_05785 4b540cde63c4ae445991af3244385582 261 SUPERFAMILY SSF56553 36 157 2.44E-32 T 31-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_05785 4b540cde63c4ae445991af3244385582 261 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 14 253 1.8E-12 T 31-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_05785 4b540cde63c4ae445991af3244385582 261 Gene3D G3DSA:3.30.1360.10 11 256 6.6E-88 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_05785 4b540cde63c4ae445991af3244385582 261 Gene3D G3DSA:3.30.70.20 166 223 6.6E-88 T 31-10-2018 DFR86_05785 4b540cde63c4ae445991af3244385582 261 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 25 65 - T 31-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 DFR86_05785 4b540cde63c4ae445991af3244385582 261 Gene3D G3DSA:2.170.120.12 37 155 6.6E-88 T 31-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_05785 4b540cde63c4ae445991af3244385582 261 SMART SM00662 11 259 1.8E-79 T 31-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_05785 4b540cde63c4ae445991af3244385582 261 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 45 156 6.1E-27 T 31-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_04245 c47c8f7baf2d9e7d8429cc40dd023086 378 SUPERFAMILY SSF56176 10 193 9.81E-28 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_04245 c47c8f7baf2d9e7d8429cc40dd023086 378 Gene3D G3DSA:3.30.465.40 2 215 4.3E-26 T 31-10-2018 DFR86_04245 c47c8f7baf2d9e7d8429cc40dd023086 378 Pfam PF01565 FAD binding domain 38 164 3.6E-19 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_06680 ad8d4af7a9acb52a44ad0b6247b8e9d7 145 Gene3D G3DSA:3.30.70.3250 28 144 5.1E-24 T 31-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 DFR86_06680 ad8d4af7a9acb52a44ad0b6247b8e9d7 145 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 27 145 19.892 T 31-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 DFR86_06680 ad8d4af7a9acb52a44ad0b6247b8e9d7 145 Pfam PF01900 Rpp14/Pop5 family 44 140 1.2E-12 T 31-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 DFR86_06680 ad8d4af7a9acb52a44ad0b6247b8e9d7 145 SUPERFAMILY SSF160350 43 141 5.36E-20 T 31-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 DFR86_03030 9fde1c15fc81c669c9fff8e64b9edff2 174 Pfam PF00156 Phosphoribosyl transferase domain 10 151 4.4E-25 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR86_03030 9fde1c15fc81c669c9fff8e64b9edff2 174 Gene3D G3DSA:3.40.50.2020 1 174 4.9E-55 T 31-10-2018 DFR86_03030 9fde1c15fc81c669c9fff8e64b9edff2 174 SUPERFAMILY SSF53271 4 166 4.33E-37 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR86_06655 00a4d43bd2637278a27d38a3158d56e2 408 SUPERFAMILY SSF53448 2 310 1.31E-61 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_06655 00a4d43bd2637278a27d38a3158d56e2 408 Pfam PF00483 Nucleotidyl transferase 2 232 5.3E-34 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR86_06655 00a4d43bd2637278a27d38a3158d56e2 408 Gene3D G3DSA:3.90.550.10 1 218 8.5E-53 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_06655 00a4d43bd2637278a27d38a3158d56e2 408 Gene3D G3DSA:2.160.10.10 219 408 9.3E-57 T 31-10-2018 DFR86_06655 00a4d43bd2637278a27d38a3158d56e2 408 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 396 7.4E-154 T 31-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 DFR86_06655 00a4d43bd2637278a27d38a3158d56e2 408 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 252 285 9.0E-9 T 31-10-2018 IPR001451 Hexapeptide repeat DFR86_06655 00a4d43bd2637278a27d38a3158d56e2 408 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 363 397 1.7E-5 T 31-10-2018 IPR001451 Hexapeptide repeat DFR86_06655 00a4d43bd2637278a27d38a3158d56e2 408 SUPERFAMILY SSF51161 241 404 2.06E-34 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily DFR86_00770 6dcd13db687962015a40c5e91147a9ce 357 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 56 339 1.5E-104 T 31-10-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 DFR86_00770 6dcd13db687962015a40c5e91147a9ce 357 Pfam PF03824 High-affinity nickel-transport protein 53 344 2.4E-91 T 31-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 DFR86_10630 ab555ef03a2118ff0a5fc9c4432ce5f9 237 SUPERFAMILY SSF51219 2 217 1.52E-61 T 31-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily DFR86_10630 ab555ef03a2118ff0a5fc9c4432ce5f9 237 Gene3D G3DSA:3.60.160.10 2 220 6.3E-68 T 31-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily DFR86_10630 ab555ef03a2118ff0a5fc9c4432ce5f9 237 Pfam PF01987 Mitochondrial biogenesis AIM24 4 204 3.1E-52 T 31-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 DFR86_10630 ab555ef03a2118ff0a5fc9c4432ce5f9 237 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 3 216 6.7E-41 T 31-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 DFR86_05755 d04dddc94905f0bee6e7b94582a0ed14 285 Gene3D G3DSA:3.40.830.10 1 283 4.7E-66 T 31-10-2018 DFR86_05755 d04dddc94905f0bee6e7b94582a0ed14 285 Pfam PF01875 Memo-like protein 5 281 7.0E-89 T 31-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 DFR86_05755 d04dddc94905f0bee6e7b94582a0ed14 285 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 282 1.8E-96 T 31-10-2018 DFR86_05755 d04dddc94905f0bee6e7b94582a0ed14 285 Hamap MF_00055 MEMO1 family protein . 1 284 60.423 T 31-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 DFR86_01695 126778e1a3d6797e1cc8559450c54164 612 Pfam PF12222 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A 71 342 1.7E-24 T 31-10-2018 IPR021102 Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A DFR86_09905 4cf259054036e9e589c9ed2806177c4a 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 255 3.1E-39 T 31-10-2018 DFR86_09905 4cf259054036e9e589c9ed2806177c4a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.6E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09905 4cf259054036e9e589c9ed2806177c4a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.6E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09905 4cf259054036e9e589c9ed2806177c4a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.6E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09905 4cf259054036e9e589c9ed2806177c4a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.6E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09905 4cf259054036e9e589c9ed2806177c4a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 3.6E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09905 4cf259054036e9e589c9ed2806177c4a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.6E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_09905 4cf259054036e9e589c9ed2806177c4a 258 SUPERFAMILY SSF51735 3 255 1.35E-59 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_09905 4cf259054036e9e589c9ed2806177c4a 258 Gene3D G3DSA:3.40.50.720 2 256 1.5E-56 T 31-10-2018 DFR86_10830 0ff8771a9b055f6ed145b2736791208c 342 Gene3D G3DSA:1.10.10.10 273 336 8.6E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10830 0ff8771a9b055f6ed145b2736791208c 342 Gene3D G3DSA:1.10.8.60 201 272 1.6E-15 T 31-10-2018 DFR86_10830 0ff8771a9b055f6ed145b2736791208c 342 SUPERFAMILY SSF46785 280 339 2.73E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_10830 0ff8771a9b055f6ed145b2736791208c 342 SUPERFAMILY SSF52540 7 266 2.12E-31 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_10830 0ff8771a9b055f6ed145b2736791208c 342 Gene3D G3DSA:3.40.50.300 5 200 4.3E-30 T 31-10-2018 DFR86_10830 0ff8771a9b055f6ed145b2736791208c 342 Pfam PF01637 ATPase domain predominantly from Archaea 19 240 5.2E-15 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR86_04500 259fc2a29b38bd5d5b4284ee9895ab7a 586 SUPERFAMILY SSF53697 246 585 3.71E-78 T 31-10-2018 DFR86_04500 259fc2a29b38bd5d5b4284ee9895ab7a 586 Gene3D G3DSA:3.40.50.10490 242 585 3.9E-95 T 31-10-2018 DFR86_04500 259fc2a29b38bd5d5b4284ee9895ab7a 586 Gene3D G3DSA:3.40.50.10490 435 573 3.9E-95 T 31-10-2018 DFR86_04500 259fc2a29b38bd5d5b4284ee9895ab7a 586 SUPERFAMILY SSF56235 3 226 1.37E-46 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_04500 259fc2a29b38bd5d5b4284ee9895ab7a 586 Gene3D G3DSA:3.60.20.10 3 236 4.1E-51 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_04500 259fc2a29b38bd5d5b4284ee9895ab7a 586 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 3 585 1.7E-146 T 31-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 DFR86_04500 259fc2a29b38bd5d5b4284ee9895ab7a 586 Pfam PF01380 SIS domain 279 405 7.4E-26 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR86_04500 259fc2a29b38bd5d5b4284ee9895ab7a 586 Pfam PF01380 SIS domain 453 536 3.6E-9 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR86_04500 259fc2a29b38bd5d5b4284ee9895ab7a 586 Pfam PF13522 Glutamine amidotransferase domain 63 178 1.3E-16 T 31-10-2018 DFR86_04685 e638625464f987b8e2f740557ca0d57a 300 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 90 296 2.6E-69 T 31-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 DFR86_04685 e638625464f987b8e2f740557ca0d57a 300 Gene3D G3DSA:3.90.850.10 85 300 3.0E-83 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR86_04685 e638625464f987b8e2f740557ca0d57a 300 SUPERFAMILY SSF56529 80 298 8.9E-74 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR86_07800 aa3b82b0d8267299e9a94f18d75ac1c4 643 ProSitePatterns PS00455 Putative AMP-binding domain signature. 247 258 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR86_07800 aa3b82b0d8267299e9a94f18d75ac1c4 643 Gene3D G3DSA:3.30.300.30 506 637 8.2E-28 T 31-10-2018 DFR86_07800 aa3b82b0d8267299e9a94f18d75ac1c4 643 SUPERFAMILY SSF56801 15 627 7.2E-175 T 31-10-2018 DFR86_07800 aa3b82b0d8267299e9a94f18d75ac1c4 643 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 16 629 2.0E-272 T 31-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 DFR86_07800 aa3b82b0d8267299e9a94f18d75ac1c4 643 Pfam PF00501 AMP-binding enzyme 72 510 4.0E-95 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR86_07800 aa3b82b0d8267299e9a94f18d75ac1c4 643 Pfam PF13193 AMP-binding enzyme C-terminal domain 519 597 2.5E-23 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR86_07800 aa3b82b0d8267299e9a94f18d75ac1c4 643 Gene3D G3DSA:3.40.50.12780 44 504 4.0E-113 T 31-10-2018 DFR86_07800 aa3b82b0d8267299e9a94f18d75ac1c4 643 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 16 70 7.4E-22 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR86_00285 6faef4786d99c5be27dfc9a344541370 494 Gene3D G3DSA:2.130.10.10 343 472 2.2E-17 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_00285 6faef4786d99c5be27dfc9a344541370 494 Gene3D G3DSA:2.130.10.10 70 222 9.8E-24 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_00285 6faef4786d99c5be27dfc9a344541370 494 SUPERFAMILY SSF50974 293 461 2.17E-22 T 31-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 DFR86_00285 6faef4786d99c5be27dfc9a344541370 494 Gene3D G3DSA:2.130.10.10 223 341 8.9E-24 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_00285 6faef4786d99c5be27dfc9a344541370 494 SUPERFAMILY SSF51004 68 338 1.92E-40 T 31-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily DFR86_00285 6faef4786d99c5be27dfc9a344541370 494 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 129 166 2.7E-7 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_00285 6faef4786d99c5be27dfc9a344541370 494 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 257 293 5.3E-14 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_00285 6faef4786d99c5be27dfc9a344541370 494 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 391 431 3.2E-11 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_00285 6faef4786d99c5be27dfc9a344541370 494 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 211 250 2.4E-7 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_00285 6faef4786d99c5be27dfc9a344541370 494 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 172 207 2.0E-8 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_01845 4b74d765fe12d59806292948493b3ce1 649 Pfam PF00270 DEAD/DEAH box helicase 8 145 1.0E-12 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_01845 4b74d765fe12d59806292948493b3ce1 649 Gene3D G3DSA:1.10.3380.20 394 551 9.9E-8 T 31-10-2018 DFR86_01845 4b74d765fe12d59806292948493b3ce1 649 SUPERFAMILY SSF158702 468 562 1.8E-7 T 31-10-2018 DFR86_01845 4b74d765fe12d59806292948493b3ce1 649 SUPERFAMILY SSF52540 9 330 1.45E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01845 4b74d765fe12d59806292948493b3ce1 649 SMART SM00382 8 155 0.0099 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_01845 4b74d765fe12d59806292948493b3ce1 649 Gene3D G3DSA:3.40.50.300 194 343 3.5E-29 T 31-10-2018 DFR86_01845 4b74d765fe12d59806292948493b3ce1 649 SMART SM00490 225 320 6.7E-24 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_01845 4b74d765fe12d59806292948493b3ce1 649 Gene3D G3DSA:3.40.50.300 1 162 9.7E-35 T 31-10-2018 DFR86_01845 4b74d765fe12d59806292948493b3ce1 649 Pfam PF00271 Helicase conserved C-terminal domain 200 320 1.1E-17 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_01845 4b74d765fe12d59806292948493b3ce1 649 SMART SM00487 4 166 1.3E-6 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_02775 584ba2c4eb3229be813834993ab3f59b 220 SUPERFAMILY SSF48371 79 218 7.2E-6 T 31-10-2018 IPR016024 Armadillo-type fold DFR86_07355 51f5ab5c1d34b570ef5e3c73a426f454 172 Pfam PF04250 Protein of unknown function (DUF429) 4 77 3.4E-4 T 31-10-2018 IPR007362 Protein of unknown function DUF429 DFR86_07355 51f5ab5c1d34b570ef5e3c73a426f454 172 PIRSF PIRSF024051 1 162 8.5E-47 T 31-10-2018 IPR018036 Protein of unknown function DUF429, subgroup DFR86_02170 655207fca5c6b2e39f84824e5bbe1af4 332 SMART SM00933 55 313 3.2E-12 T 31-10-2018 IPR018977 NurA domain DFR86_02170 655207fca5c6b2e39f84824e5bbe1af4 332 Pfam PF09376 NurA domain 57 300 3.9E-10 T 31-10-2018 IPR018977 NurA domain DFR86_03680 0e0c222970cf2a1558c68512ebbb95b9 140 SUPERFAMILY SSF55961 1 124 9.47E-8 T 31-10-2018 DFR86_09390 7e0fc43d72fdc3faecc08314c94fd8c2 137 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 12 133 36.325 T 31-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 DFR86_09390 7e0fc43d72fdc3faecc08314c94fd8c2 137 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 13 132 2.2E-40 T 31-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 DFR86_09390 7e0fc43d72fdc3faecc08314c94fd8c2 137 SUPERFAMILY SSF51230 11 133 5.92E-42 T 31-10-2018 IPR011053 Single hybrid motif DFR86_09390 7e0fc43d72fdc3faecc08314c94fd8c2 137 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 55 84 - T 31-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 DFR86_09390 7e0fc43d72fdc3faecc08314c94fd8c2 137 Gene3D G3DSA:2.40.50.100 3 132 2.0E-47 T 31-10-2018 DFR86_09390 7e0fc43d72fdc3faecc08314c94fd8c2 137 Pfam PF01597 Glycine cleavage H-protein 15 133 6.9E-43 T 31-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate DFR86_07875 c05b90388efba71325635b4131e8d8a0 90 Pfam PF13740 ACT domain 5 76 4.1E-17 T 31-10-2018 DFR86_07875 c05b90388efba71325635b4131e8d8a0 90 Hamap MF_01054 UPF0237 protein . 2 90 25.804 T 31-10-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type DFR86_07875 c05b90388efba71325635b4131e8d8a0 90 Gene3D G3DSA:3.30.70.260 1 90 3.0E-27 T 31-10-2018 DFR86_07875 c05b90388efba71325635b4131e8d8a0 90 SUPERFAMILY SSF55021 4 84 2.14E-21 T 31-10-2018 DFR86_00415 6f3191c79460be23816db959093d770e 715 Pfam PF13091 PLD-like domain 586 708 1.3E-23 T 31-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 DFR86_00415 6f3191c79460be23816db959093d770e 715 Gene3D G3DSA:3.30.870.10 536 714 2.3E-25 T 31-10-2018 DFR86_00415 6f3191c79460be23816db959093d770e 715 SUPERFAMILY SSF56024 583 714 2.88E-21 T 31-10-2018 DFR86_03195 0301e98d3102c2c236b6d23ad94839a1 624 Pfam PF00482 Type II secretion system (T2SS), protein F 136 263 1.5E-6 T 31-10-2018 IPR018076 Type II secretion system F domain DFR86_03195 0301e98d3102c2c236b6d23ad94839a1 624 Pfam PF00482 Type II secretion system (T2SS), protein F 393 519 3.2E-11 T 31-10-2018 IPR018076 Type II secretion system F domain DFR86_03195 0301e98d3102c2c236b6d23ad94839a1 624 SUPERFAMILY SSF103473 256 617 5.49E-6 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_00500 9b2cdab0e0460b98d2fe969bb472f430 301 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 47 203 2.8E-22 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR86_00500 9b2cdab0e0460b98d2fe969bb472f430 301 SUPERFAMILY SSF52518 14 297 6.13E-78 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_00500 9b2cdab0e0460b98d2fe969bb472f430 301 Gene3D G3DSA:3.40.50.970 89 299 3.4E-69 T 31-10-2018 DFR86_00500 9b2cdab0e0460b98d2fe969bb472f430 301 Gene3D G3DSA:3.40.50.970 8 88 3.1E-7 T 31-10-2018 DFR86_09745 88b7f033560a8a5ebecd65421610980f 90 Gene3D G3DSA:2.40.10.230 2 82 1.4E-13 T 31-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain DFR86_09745 88b7f033560a8a5ebecd65421610980f 90 SUPERFAMILY SSF50447 8 72 1.66E-9 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR86_04320 6e088b0199077d093c549634335f0cfe 411 Pfam PF07969 Amidohydrolase family 112 391 8.3E-28 T 31-10-2018 IPR013108 Amidohydrolase 3 DFR86_04320 6e088b0199077d093c549634335f0cfe 411 Gene3D G3DSA:3.20.20.140 48 351 2.8E-136 T 31-10-2018 DFR86_04320 6e088b0199077d093c549634335f0cfe 411 SUPERFAMILY SSF51338 2 405 9.26E-10 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04320 6e088b0199077d093c549634335f0cfe 411 Gene3D G3DSA:2.30.40.10 6 394 2.8E-136 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04320 6e088b0199077d093c549634335f0cfe 411 SUPERFAMILY SSF51556 47 362 4.92E-89 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_06205 510a02261915c337167e152a5b63305e 435 Pfam PF03144 Elongation factor Tu domain 2 247 312 3.1E-16 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 DFR86_06205 510a02261915c337167e152a5b63305e 435 Gene3D G3DSA:3.40.50.300 1 225 5.6E-83 T 31-10-2018 DFR86_06205 510a02261915c337167e152a5b63305e 435 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 3 431 1.7E-195 T 31-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 DFR86_06205 510a02261915c337167e152a5b63305e 435 Pfam PF03143 Elongation factor Tu C-terminal domain 321 427 2.8E-36 T 31-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal DFR86_06205 510a02261915c337167e152a5b63305e 435 Hamap MF_00118_A Elongation factor Tu [tuf]. 1 430 59.628 T 31-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 DFR86_06205 510a02261915c337167e152a5b63305e 435 Gene3D G3DSA:2.40.30.10 228 321 3.5E-36 T 31-10-2018 DFR86_06205 510a02261915c337167e152a5b63305e 435 Pfam PF00009 Elongation factor Tu GTP binding domain 4 214 7.8E-51 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06205 510a02261915c337167e152a5b63305e 435 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 31-10-2018 IPR031157 Tr-type G domain, conserved site DFR86_06205 510a02261915c337167e152a5b63305e 435 SUPERFAMILY SSF50465 324 427 1.44E-39 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal DFR86_06205 510a02261915c337167e152a5b63305e 435 SUPERFAMILY SSF50447 230 320 2.04E-27 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR86_06205 510a02261915c337167e152a5b63305e 435 PRINTS PR00315 GTP-binding elongation factor signature 103 114 6.0E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06205 510a02261915c337167e152a5b63305e 435 PRINTS PR00315 GTP-binding elongation factor signature 147 156 6.0E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06205 510a02261915c337167e152a5b63305e 435 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.0E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06205 510a02261915c337167e152a5b63305e 435 PRINTS PR00315 GTP-binding elongation factor signature 87 97 6.0E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06205 510a02261915c337167e152a5b63305e 435 PRINTS PR00315 GTP-binding elongation factor signature 8 21 6.0E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06205 510a02261915c337167e152a5b63305e 435 SUPERFAMILY SSF52540 1 248 1.36E-70 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06205 510a02261915c337167e152a5b63305e 435 Gene3D G3DSA:2.40.30.10 322 428 4.4E-43 T 31-10-2018 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 PIRSF PIRSF006540 1 233 5.1E-100 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 Gene3D G3DSA:3.40.50.150 56 233 2.2E-74 T 31-10-2018 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 Gene3D G3DSA:3.30.200.20 1 55 1.7E-26 T 31-10-2018 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 SUPERFAMILY SSF53335 11 230 4.49E-50 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 SMART SM01206 8 233 3.3E-146 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 Pfam PF01269 Fibrillarin 10 232 4.6E-102 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 ProSitePatterns PS00566 Fibrillarin signature. 103 117 - T 31-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 21 232 43.848 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 PRINTS PR00052 Fibrillarin signature 210 231 3.3E-71 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 PRINTS PR00052 Fibrillarin signature 128 157 3.3E-71 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 PRINTS PR00052 Fibrillarin signature 158 187 3.3E-71 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 PRINTS PR00052 Fibrillarin signature 28 47 3.3E-71 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 PRINTS PR00052 Fibrillarin signature 78 99 3.3E-71 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 PRINTS PR00052 Fibrillarin signature 51 70 3.3E-71 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_09715 0f688ec9bba32402b9d7d02d19d9a6d7 233 PRINTS PR00052 Fibrillarin signature 103 120 3.3E-71 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR86_01670 313f50613f5c320fa8be515897b464c9 162 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 159 3.6E-70 T 31-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 DFR86_01670 313f50613f5c320fa8be515897b464c9 162 Pfam PF00694 Aconitase C-terminal domain 40 105 8.1E-22 T 31-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 DFR86_01670 313f50613f5c320fa8be515897b464c9 162 SUPERFAMILY SSF52016 3 158 5.89E-47 T 31-10-2018 DFR86_01670 313f50613f5c320fa8be515897b464c9 162 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 162 35.345 T 31-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 DFR86_01670 313f50613f5c320fa8be515897b464c9 162 Gene3D G3DSA:3.20.19.10 1 162 7.9E-58 T 31-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 DFR86_04180 dfb767f195da512c6cd79a9a7e6e9f6a 439 Pfam PF00202 Aminotransferase class-III 41 436 5.5E-105 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_04180 dfb767f195da512c6cd79a9a7e6e9f6a 439 Gene3D G3DSA:3.90.1150.10 29 432 9.1E-138 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_04180 dfb767f195da512c6cd79a9a7e6e9f6a 439 SUPERFAMILY SSF53383 33 437 3.98E-119 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_04180 dfb767f195da512c6cd79a9a7e6e9f6a 439 Gene3D G3DSA:3.40.640.10 80 337 9.1E-138 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_04180 dfb767f195da512c6cd79a9a7e6e9f6a 439 PIRSF PIRSF000521 3 147 9.1E-11 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_04180 dfb767f195da512c6cd79a9a7e6e9f6a 439 PIRSF PIRSF000521 142 439 4.7E-37 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_09135 185e296c9a9fc58af889775097172203 471 Gene3D G3DSA:3.30.590.10 107 459 3.0E-129 T 31-10-2018 DFR86_09135 185e296c9a9fc58af889775097172203 471 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 96 2.7E-23 T 31-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR86_09135 185e296c9a9fc58af889775097172203 471 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 470 3.7E-176 T 31-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_09135 185e296c9a9fc58af889775097172203 471 SUPERFAMILY SSF55931 105 470 1.37E-117 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR86_09135 185e296c9a9fc58af889775097172203 471 Pfam PF00120 Glutamine synthetase, catalytic domain 105 468 8.3E-132 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_09135 185e296c9a9fc58af889775097172203 471 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 255 270 - T 31-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR86_09135 185e296c9a9fc58af889775097172203 471 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 31-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR86_09135 185e296c9a9fc58af889775097172203 471 Gene3D G3DSA:3.10.20.70 4 106 8.6E-28 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_09135 185e296c9a9fc58af889775097172203 471 SUPERFAMILY SSF54368 5 99 6.54E-25 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_09135 185e296c9a9fc58af889775097172203 471 SMART SM01230 104 381 1.0E-127 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_08410 4eb67f1b58afc124504ab3bbd9251042 192 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 192 22.779 T 31-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08410 4eb67f1b58afc124504ab3bbd9251042 192 Pfam PF00156 Phosphoribosyl transferase domain 43 153 1.4E-21 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR86_08410 4eb67f1b58afc124504ab3bbd9251042 192 Gene3D G3DSA:3.40.50.2020 2 191 3.7E-52 T 31-10-2018 DFR86_08410 4eb67f1b58afc124504ab3bbd9251042 192 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 6 167 4.4E-42 T 31-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_08410 4eb67f1b58afc124504ab3bbd9251042 192 SUPERFAMILY SSF53271 9 168 1.19E-43 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR86_09545 32a1fe870a9c7b59043fa94e9be10136 422 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 101 115 - T 31-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_09545 32a1fe870a9c7b59043fa94e9be10136 422 PIRSF PIRSF500824 1 422 9.2E-203 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_09545 32a1fe870a9c7b59043fa94e9be10136 422 PIRSF PIRSF001413 4 422 5.3E-145 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_09545 32a1fe870a9c7b59043fa94e9be10136 422 Gene3D G3DSA:3.40.50.1100 8 411 5.9E-170 T 31-10-2018 DFR86_09545 32a1fe870a9c7b59043fa94e9be10136 422 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 73 405 1.4E-43 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR86_09545 32a1fe870a9c7b59043fa94e9be10136 422 SUPERFAMILY SSF53686 25 414 2.1E-102 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR86_09545 32a1fe870a9c7b59043fa94e9be10136 422 Gene3D G3DSA:3.40.50.1100 9 233 5.9E-170 T 31-10-2018 DFR86_09545 32a1fe870a9c7b59043fa94e9be10136 422 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 16 418 40.829 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_09545 32a1fe870a9c7b59043fa94e9be10136 422 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 8 416 4.1E-189 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR86_00180 2ad7cbb9e7c0d013b86711627f8944a4 240 Pfam PF03787 RAMP superfamily 36 212 4.3E-13 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 SUPERFAMILY SSF50447 207 317 4.86E-35 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 Gene3D G3DSA:3.40.50.300 2 207 1.1E-62 T 31-10-2018 DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 PRINTS PR00315 GTP-binding elongation factor signature 106 117 1.1E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 PRINTS PR00315 GTP-binding elongation factor signature 144 153 1.1E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.1E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 PRINTS PR00315 GTP-binding elongation factor signature 90 100 1.1E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 SUPERFAMILY SSF50465 324 414 5.28E-30 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 2 414 58.648 T 31-10-2018 IPR022424 Translation initiation factor 2, gamma subunit DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 Gene3D G3DSA:2.40.30.10 208 322 2.9E-43 T 31-10-2018 DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 198 5.3E-13 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 SUPERFAMILY SSF52540 4 205 5.88E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 6 414 1.7E-194 T 31-10-2018 IPR022424 Translation initiation factor 2, gamma subunit DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 Gene3D G3DSA:2.40.30.10 323 415 3.8E-32 T 31-10-2018 DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 3.4E-30 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR86_06065 cb7de64fd99ec3a06e7cedf732531cf8 415 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 328 413 6.2E-30 T 31-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 SUPERFAMILY SSF47323 497 619 6.54E-27 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 63 619 4.6E-106 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 Hamap MF_00123 Arginine--tRNA ligase [argS]. 17 619 21.998 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 Gene3D G3DSA:3.30.1360.70 2 94 3.9E-6 T 31-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 SMART SM00836 503 619 2.9E-29 T 31-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 Pfam PF05746 DALR anticodon binding domain 503 619 4.6E-29 T 31-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 Pfam PF00750 tRNA synthetases class I (R) 96 164 6.4E-14 T 31-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 Pfam PF00750 tRNA synthetases class I (R) 236 492 1.0E-17 T 31-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 PRINTS PR01038 Arginyl-tRNA synthetase signature 142 155 6.8E-14 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 PRINTS PR01038 Arginyl-tRNA synthetase signature 118 134 6.8E-14 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 PRINTS PR01038 Arginyl-tRNA synthetase signature 103 118 6.8E-14 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 SUPERFAMILY SSF52374 98 496 4.69E-65 T 31-10-2018 DFR86_09665 149b69da627752ef3abdb0a893940eb7 619 Gene3D G3DSA:1.10.730.10 503 619 9.2E-29 T 31-10-2018 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 Pfam PF03129 Anticodon binding domain 469 557 6.1E-21 T 31-10-2018 IPR004154 Anticodon-binding DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 Gene3D G3DSA:3.30.930.10 14 452 7.6E-126 T 31-10-2018 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 165 238 8.9E-8 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 8 557 7.2E-188 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 Gene3D G3DSA:3.40.50.800 460 565 8.8E-34 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 SUPERFAMILY SSF55681 9 471 2.87E-115 T 31-10-2018 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 Gene3D G3DSA:1.20.1430.20 87 150 7.6E-126 T 31-10-2018 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 Gene3D G3DSA:1.10.30.30 354 422 7.6E-126 T 31-10-2018 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 PRINTS PR01043 Glycyl-tRNA synthetase signature 196 213 6.5E-53 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 PRINTS PR01043 Glycyl-tRNA synthetase signature 164 181 6.5E-53 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 6.5E-53 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 PRINTS PR01043 Glycyl-tRNA synthetase signature 213 223 6.5E-53 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 PRINTS PR01043 Glycyl-tRNA synthetase signature 428 440 6.5E-53 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 PRINTS PR01043 Glycyl-tRNA synthetase signature 145 157 6.5E-53 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 PRINTS PR01043 Glycyl-tRNA synthetase signature 505 524 6.5E-53 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR86_05915 dcfa71251f2b507b1fdf675cf4313d3c 565 SUPERFAMILY SSF52954 455 560 1.96E-34 T 31-10-2018 DFR86_01100 ec334155d5d974b4dbf582f6056fc623 209 Pfam PF00117 Glutamine amidotransferase class-I 29 169 3.4E-18 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR86_01100 ec334155d5d974b4dbf582f6056fc623 209 Gene3D G3DSA:3.40.50.880 1 209 1.4E-47 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_01100 ec334155d5d974b4dbf582f6056fc623 209 SUPERFAMILY SSF52317 29 208 1.2E-42 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_03740 60c424a3e864a92acf930d745ad0770e 312 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_03740 60c424a3e864a92acf930d745ad0770e 312 SMART SM00382 26 209 4.5E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_03740 60c424a3e864a92acf930d745ad0770e 312 Gene3D G3DSA:3.40.50.300 1 231 4.2E-56 T 31-10-2018 DFR86_03740 60c424a3e864a92acf930d745ad0770e 312 Pfam PF00005 ABC transporter 17 160 4.0E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_03740 60c424a3e864a92acf930d745ad0770e 312 SUPERFAMILY SSF52540 1 222 4.02E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04195 e4fd2d492bc0d7e7036b71c174a53552 347 Gene3D G3DSA:3.30.360.10 119 296 8.0E-49 T 31-10-2018 DFR86_04195 e4fd2d492bc0d7e7036b71c174a53552 347 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 111 2.5E-9 T 31-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 DFR86_04195 e4fd2d492bc0d7e7036b71c174a53552 347 Gene3D G3DSA:3.40.50.720 37 333 8.0E-49 T 31-10-2018 DFR86_04195 e4fd2d492bc0d7e7036b71c174a53552 347 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 341 4.5E-13 T 31-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 DFR86_04195 e4fd2d492bc0d7e7036b71c174a53552 347 SUPERFAMILY SSF51735 1 133 1.83E-13 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_07605 d6f1aba2a32b8e6dd7733f1d46e1e401 312 Pfam PF01171 PP-loop family 50 224 3.4E-13 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 DFR86_07605 d6f1aba2a32b8e6dd7733f1d46e1e401 312 PIRSF PIRSF004976 1 312 4.7E-85 T 31-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 DFR86_07605 d6f1aba2a32b8e6dd7733f1d46e1e401 312 SUPERFAMILY SSF52402 25 236 1.1E-40 T 31-10-2018 DFR86_07605 d6f1aba2a32b8e6dd7733f1d46e1e401 312 Gene3D G3DSA:3.40.50.620 1 311 6.6E-70 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_04540 f192272657df704ad9772a5d4e8903c7 158 SUPERFAMILY SSF55729 3 147 3.44E-28 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR86_04540 f192272657df704ad9772a5d4e8903c7 158 Gene3D G3DSA:3.40.630.30 1 151 4.3E-29 T 31-10-2018 DFR86_04540 f192272657df704ad9772a5d4e8903c7 158 Pfam PF00583 Acetyltransferase (GNAT) family 42 143 2.8E-16 T 31-10-2018 IPR000182 GNAT domain DFR86_06235 733531d83f45a6a6a38e4f8a70b853d5 392 Gene3D G3DSA:1.10.150.390 338 383 5.3E-23 T 31-10-2018 DFR86_06235 733531d83f45a6a6a38e4f8a70b853d5 392 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 21 388 2.2E-160 T 31-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06235 733531d83f45a6a6a38e4f8a70b853d5 392 Pfam PF04998 RNA polymerase Rpb1, domain 5 57 337 7.5E-58 T 31-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06235 733531d83f45a6a6a38e4f8a70b853d5 392 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 2 390 41.314 T 31-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_06235 733531d83f45a6a6a38e4f8a70b853d5 392 SUPERFAMILY SSF64484 15 388 3.66E-105 T 31-10-2018 DFR86_09585 86b23be66d14e2ca6e93e626ea80a2ae 393 Gene3D G3DSA:3.40.50.1100 47 363 3.3E-116 T 31-10-2018 DFR86_09585 86b23be66d14e2ca6e93e626ea80a2ae 393 PIRSF PIRSF038945 31 386 6.7E-131 T 31-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 DFR86_09585 86b23be66d14e2ca6e93e626ea80a2ae 393 Gene3D G3DSA:3.40.50.1100 91 188 3.3E-116 T 31-10-2018 DFR86_09585 86b23be66d14e2ca6e93e626ea80a2ae 393 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 83 96 - T 31-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 DFR86_09585 86b23be66d14e2ca6e93e626ea80a2ae 393 TIGRFAM TIGR00260 thrC: threonine synthase 45 364 1.4E-86 T 31-10-2018 IPR004450 Threonine synthase-like DFR86_09585 86b23be66d14e2ca6e93e626ea80a2ae 393 SUPERFAMILY SSF53686 2 375 1.44E-104 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR86_09585 86b23be66d14e2ca6e93e626ea80a2ae 393 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 357 1.8E-68 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR86_10715 c8747586c8f7f67061f8dd9f8856d59c 125 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 22 89 4.4E-13 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR86_10715 c8747586c8f7f67061f8dd9f8856d59c 125 SMART SM00347 20 121 0.003 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR86_10715 c8747586c8f7f67061f8dd9f8856d59c 125 Gene3D G3DSA:1.10.10.10 15 116 7.2E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10715 c8747586c8f7f67061f8dd9f8856d59c 125 SUPERFAMILY SSF46785 21 119 7.36E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_01205 81f66d020d9ad9083bb63178efe425aa 340 Pfam PF01890 Cobalamin synthesis G C-terminus 219 334 1.2E-15 T 31-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 DFR86_01205 81f66d020d9ad9083bb63178efe425aa 340 SUPERFAMILY SSF159672 6 224 4.97E-44 T 31-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 DFR86_01205 81f66d020d9ad9083bb63178efe425aa 340 SUPERFAMILY SSF159664 219 335 1.05E-23 T 31-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 DFR86_01205 81f66d020d9ad9083bb63178efe425aa 340 Gene3D G3DSA:3.30.420.180 216 340 5.9E-28 T 31-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 DFR86_01205 81f66d020d9ad9083bb63178efe425aa 340 Gene3D G3DSA:3.40.50.11220 1 117 1.1E-36 T 31-10-2018 DFR86_01205 81f66d020d9ad9083bb63178efe425aa 340 Pfam PF11760 Cobalamin synthesis G N-terminal 45 122 2.5E-27 T 31-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 DFR86_01205 81f66d020d9ad9083bb63178efe425aa 340 Gene3D G3DSA:3.40.1390.40 127 205 8.1E-6 T 31-10-2018 DFR86_06225 39fa508751724016d1ac87b6b549a43f 143 Gene3D G3DSA:3.30.300.20 75 142 5.4E-25 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR86_06225 39fa508751724016d1ac87b6b549a43f 143 SUPERFAMILY SSF54814 15 75 1.44E-12 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 DFR86_06225 39fa508751724016d1ac87b6b549a43f 143 Gene3D G3DSA:3.30.300.20 2 74 1.7E-31 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR86_06225 39fa508751724016d1ac87b6b549a43f 143 SUPERFAMILY SSF54814 76 139 1.62E-10 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 DFR86_06225 39fa508751724016d1ac87b6b549a43f 143 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 2 143 32.054 T 31-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal DFR86_06225 39fa508751724016d1ac87b6b549a43f 143 Pfam PF07650 KH domain 13 88 4.2E-14 T 31-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06225 39fa508751724016d1ac87b6b549a43f 143 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 3 143 3.9E-53 T 31-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal DFR86_06225 39fa508751724016d1ac87b6b549a43f 143 SMART SM00322 33 100 0.0017 T 31-10-2018 IPR004087 K Homology domain GO:0003676 DFR86_09525 580048c963cdd4358c5bfa89732a899a 421 Gene3D G3DSA:3.60.120.10 2 421 7.4E-146 T 31-10-2018 IPR005801 ADC synthase GO:0009058 DFR86_09525 580048c963cdd4358c5bfa89732a899a 421 Pfam PF00425 chorismate binding enzyme 158 410 2.5E-90 T 31-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal DFR86_09525 580048c963cdd4358c5bfa89732a899a 421 Pfam PF04715 Anthranilate synthase component I, N terminal region 12 131 1.0E-13 T 31-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR86_09525 580048c963cdd4358c5bfa89732a899a 421 PRINTS PR00095 Anthranilate synthase component I signature 273 286 3.8E-18 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR86_09525 580048c963cdd4358c5bfa89732a899a 421 PRINTS PR00095 Anthranilate synthase component I signature 353 367 3.8E-18 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR86_09525 580048c963cdd4358c5bfa89732a899a 421 PRINTS PR00095 Anthranilate synthase component I signature 259 272 3.8E-18 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR86_09525 580048c963cdd4358c5bfa89732a899a 421 PRINTS PR00095 Anthranilate synthase component I signature 367 381 3.8E-18 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR86_09525 580048c963cdd4358c5bfa89732a899a 421 SUPERFAMILY SSF56322 8 419 4.32E-131 T 31-10-2018 IPR005801 ADC synthase GO:0009058 DFR86_06730 6928144735f1438a3c0b9cd87408e0a2 228 SUPERFAMILY SSF52980 3 130 2.32E-31 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR86_06730 6928144735f1438a3c0b9cd87408e0a2 228 Gene3D G3DSA:1.10.150.20 143 213 1.6E-16 T 31-10-2018 DFR86_06730 6928144735f1438a3c0b9cd87408e0a2 228 SMART SM00891 3 83 6.5E-24 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 DFR86_06730 6928144735f1438a3c0b9cd87408e0a2 228 Gene3D G3DSA:3.40.50.10130 1 142 2.0E-38 T 31-10-2018 DFR86_06730 6928144735f1438a3c0b9cd87408e0a2 228 Pfam PF02732 ERCC4 domain 7 127 8.7E-22 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 DFR86_06730 6928144735f1438a3c0b9cd87408e0a2 228 SUPERFAMILY SSF47781 139 219 1.59E-15 T 31-10-2018 IPR010994 RuvA domain 2-like DFR86_10990 046872b1c402122a10ea8c9d9df0d91f 313 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 3.2E-70 T 31-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 DFR86_10990 046872b1c402122a10ea8c9d9df0d91f 313 Gene3D G3DSA:3.20.20.140 1 312 3.3E-58 T 31-10-2018 DFR86_10990 046872b1c402122a10ea8c9d9df0d91f 313 SUPERFAMILY SSF51556 4 310 1.36E-48 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_07810 f0f22a625ca2cfd2e6155951b9632def 241 SUPERFAMILY SSF52540 14 218 1.58E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07810 f0f22a625ca2cfd2e6155951b9632def 241 Gene3D G3DSA:3.40.50.300 2 238 2.3E-52 T 31-10-2018 DFR86_07810 f0f22a625ca2cfd2e6155951b9632def 241 Pfam PF01935 Domain of unknown function DUF87 6 99 6.8E-15 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR86_01945 7e5da35b150fe90f892e84990ede93bf 203 Gene3D G3DSA:1.20.144.10 1 112 7.9E-6 T 31-10-2018 DFR86_01945 7e5da35b150fe90f892e84990ede93bf 203 Gene3D G3DSA:1.20.144.10 113 193 1.7E-18 T 31-10-2018 DFR86_01945 7e5da35b150fe90f892e84990ede93bf 203 SUPERFAMILY SSF48317 10 192 8.9E-46 T 31-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily DFR86_01945 7e5da35b150fe90f892e84990ede93bf 203 Pfam PF01569 PAP2 superfamily 78 186 2.9E-22 T 31-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DFR86_01945 7e5da35b150fe90f892e84990ede93bf 203 SMART SM00014 76 186 8.5E-21 T 31-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DFR86_01420 6681c63d03d4ccb6fb766cec419ce2e6 167 SUPERFAMILY SSF46785 4 53 1.44E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_10190 fe86660475258ad574f6463d15e5b6b0 128 Gene3D G3DSA:1.10.10.10 15 118 1.4E-30 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10190 fe86660475258ad574f6463d15e5b6b0 128 SMART SM00347 21 122 7.8E-4 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR86_10190 fe86660475258ad574f6463d15e5b6b0 128 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 25 95 1.5E-14 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR86_10190 fe86660475258ad574f6463d15e5b6b0 128 SUPERFAMILY SSF46785 20 110 2.15E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_08370 093e0630ead2383c35a2ec29bc56e184 212 SUPERFAMILY SSF111278 3 188 4.45E-51 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 DFR86_08370 093e0630ead2383c35a2ec29bc56e184 212 Gene3D G3DSA:3.30.1960.10 1 189 3.1E-58 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 DFR86_08370 093e0630ead2383c35a2ec29bc56e184 212 Pfam PF02676 Methyltransferase TYW3 8 187 3.6E-31 T 31-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 DFR86_08370 093e0630ead2383c35a2ec29bc56e184 212 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 5 191 29.624 T 31-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 DFR86_10380 7c6f68fc5a5d1aca53e20e029cce8b7d 228 Pfam PF04321 RmlD substrate binding domain 55 175 7.7E-17 T 31-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 DFR86_10380 7c6f68fc5a5d1aca53e20e029cce8b7d 228 Gene3D G3DSA:3.90.25.10 133 200 8.2E-34 T 31-10-2018 DFR86_10380 7c6f68fc5a5d1aca53e20e029cce8b7d 228 Gene3D G3DSA:3.40.50.720 32 185 8.2E-34 T 31-10-2018 DFR86_10380 7c6f68fc5a5d1aca53e20e029cce8b7d 228 SUPERFAMILY SSF51735 32 200 2.67E-28 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_05965 9d056d34be3bdfb43707d439798d6c82 61 SUPERFAMILY SSF57829 11 57 2.2E-14 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR86_05965 9d056d34be3bdfb43707d439798d6c82 61 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 11 57 16.748 T 31-10-2018 IPR022845 Ribosomal protein S27ae DFR86_05965 9d056d34be3bdfb43707d439798d6c82 61 SMART SM01402 11 54 7.5E-19 T 31-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR86_05965 9d056d34be3bdfb43707d439798d6c82 61 Pfam PF01599 Ribosomal protein S27a 14 54 3.6E-14 T 31-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR86_05965 9d056d34be3bdfb43707d439798d6c82 61 Gene3D G3DSA:2.20.25.660 1 58 7.2E-11 T 31-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR86_08155 bf3d3349ec7324453f68287f62a979f2 477 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 30 55 3.2E-14 T 31-10-2018 DFR86_08155 bf3d3349ec7324453f68287f62a979f2 477 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 108 127 3.2E-14 T 31-10-2018 DFR86_08155 bf3d3349ec7324453f68287f62a979f2 477 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 227 246 3.2E-14 T 31-10-2018 DFR86_08155 bf3d3349ec7324453f68287f62a979f2 477 Gene3D G3DSA:1.10.246.230 215 310 9.6E-20 T 31-10-2018 DFR86_08155 bf3d3349ec7324453f68287f62a979f2 477 SUPERFAMILY SSF56235 6 474 1.1E-100 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_08155 bf3d3349ec7324453f68287f62a979f2 477 Pfam PF01019 Gamma-glutamyltranspeptidase 23 470 4.2E-73 T 31-10-2018 DFR86_08155 bf3d3349ec7324453f68287f62a979f2 477 Gene3D G3DSA:3.60.20.40 313 474 2.5E-24 T 31-10-2018 DFR86_05220 a9596883decb91b2612410d07820c535 219 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 14 188 1.8E-69 T 31-10-2018 IPR005273 Uracil-DNA glycosylase family 4 DFR86_05220 a9596883decb91b2612410d07820c535 219 Pfam PF03167 Uracil DNA glycosylase superfamily 28 181 2.1E-45 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR86_05220 a9596883decb91b2612410d07820c535 219 Gene3D G3DSA:3.40.470.10 1 191 4.1E-69 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR86_05220 a9596883decb91b2612410d07820c535 219 SUPERFAMILY SSF52141 4 189 3.2E-58 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR86_05220 a9596883decb91b2612410d07820c535 219 SMART SM00986 28 182 1.6E-37 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR86_05220 a9596883decb91b2612410d07820c535 219 SMART SM00987 28 182 1.6E-37 T 31-10-2018 DFR86_07395 4803144be8435f1e91c4729034430ea0 92 Gene3D G3DSA:1.10.10.10 2 79 1.8E-12 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_07395 4803144be8435f1e91c4729034430ea0 92 SUPERFAMILY SSF46785 2 82 7.68E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_07395 4803144be8435f1e91c4729034430ea0 92 Pfam PF01022 Bacterial regulatory protein, arsR family 5 48 4.0E-8 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_07395 4803144be8435f1e91c4729034430ea0 92 SMART SM00418 2 74 0.0041 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_06525 8fe74ce028d7124c1e798a15984f37e3 124 Gene3D G3DSA:2.40.50.140 1 124 1.0E-38 T 31-10-2018 DFR86_06525 8fe74ce028d7124c1e798a15984f37e3 124 Pfam PF16992 DNA-directed RNA polymerase, subunit G 8 123 1.5E-42 T 31-10-2018 IPR031555 DNA-directed RNA polymerase, subunit G DFR86_09220 917334104aca12c05423eaf458c35352 223 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 7 222 5.9E-58 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 DFR86_09220 917334104aca12c05423eaf458c35352 223 SUPERFAMILY SSF55909 4 222 1.37E-67 T 31-10-2018 DFR86_09220 917334104aca12c05423eaf458c35352 223 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 223 80.92 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 DFR86_09220 917334104aca12c05423eaf458c35352 223 PIRSF PIRSF006413 2 223 5.3E-79 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 DFR86_09220 917334104aca12c05423eaf458c35352 223 SMART SM00654 4 203 1.5E-89 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 DFR86_09220 917334104aca12c05423eaf458c35352 223 Pfam PF01912 eIF-6 family 5 203 1.5E-68 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 DFR86_09220 917334104aca12c05423eaf458c35352 223 Gene3D G3DSA:3.75.10.10 3 222 1.8E-73 T 31-10-2018 DFR86_01055 764928162f1db2c97d9ca81bffac136f 373 SUPERFAMILY SSF47203 214 366 9.18E-31 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR86_01055 764928162f1db2c97d9ca81bffac136f 373 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 109 203 4.1E-18 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 DFR86_01055 764928162f1db2c97d9ca81bffac136f 373 Gene3D G3DSA:1.10.540.10 2 107 4.3E-19 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 DFR86_01055 764928162f1db2c97d9ca81bffac136f 373 Gene3D G3DSA:1.20.140.10 220 364 6.3E-32 T 31-10-2018 DFR86_01055 764928162f1db2c97d9ca81bffac136f 373 Gene3D G3DSA:2.40.110.10 108 219 5.3E-28 T 31-10-2018 DFR86_01055 764928162f1db2c97d9ca81bffac136f 373 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 215 360 5.9E-37 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DFR86_01055 764928162f1db2c97d9ca81bffac136f 373 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 105 2.3E-15 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 DFR86_01055 764928162f1db2c97d9ca81bffac136f 373 SUPERFAMILY SSF56645 4 225 4.32E-51 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR86_09625 391918c44594375f565f78b470275a12 238 SUPERFAMILY SSF46785 30 94 1.05E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_09625 391918c44594375f565f78b470275a12 238 Gene3D G3DSA:1.10.10.10 23 152 2.8E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_11210 1dade5c13f1264b79e80cebd0bda7e25 384 Gene3D G3DSA:3.40.50.970 6 254 2.1E-100 T 31-10-2018 DFR86_11210 1dade5c13f1264b79e80cebd0bda7e25 384 SUPERFAMILY SSF52518 9 253 1.62E-67 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_11210 1dade5c13f1264b79e80cebd0bda7e25 384 Gene3D G3DSA:3.40.50.920 255 383 7.0E-41 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR86_11210 1dade5c13f1264b79e80cebd0bda7e25 384 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 264 364 3.8E-34 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II DFR86_11210 1dade5c13f1264b79e80cebd0bda7e25 384 SUPERFAMILY SSF52922 255 375 6.28E-32 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR86_11210 1dade5c13f1264b79e80cebd0bda7e25 384 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 20 243 4.7E-71 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DFR86_10780 12c0647127de291c819730fd18c83687 230 Pfam PF13183 4Fe-4S dicluster domain 62 123 2.3E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_10780 12c0647127de291c819730fd18c83687 230 SUPERFAMILY SSF46548 60 139 5.06E-15 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_10780 12c0647127de291c819730fd18c83687 230 Gene3D G3DSA:1.10.1060.10 28 141 8.2E-11 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_10780 12c0647127de291c819730fd18c83687 230 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 109 120 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_06105 de5bbc2395fcff17655fe833125f0200 438 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 185 3.6E-15 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DFR86_06105 de5bbc2395fcff17655fe833125f0200 438 SUPERFAMILY SSF52317 239 430 3.44E-25 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_06105 de5bbc2395fcff17655fe833125f0200 438 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 4 433 41.311 T 31-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 DFR86_06105 de5bbc2395fcff17655fe833125f0200 438 SUPERFAMILY SSF52540 5 189 6.16E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06105 de5bbc2395fcff17655fe833125f0200 438 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 6 434 2.8E-129 T 31-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 DFR86_06105 de5bbc2395fcff17655fe833125f0200 438 Gene3D G3DSA:3.40.50.880 237 438 1.7E-7 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_06105 de5bbc2395fcff17655fe833125f0200 438 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 245 430 2.8E-39 T 31-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 DFR86_06105 de5bbc2395fcff17655fe833125f0200 438 Gene3D G3DSA:3.40.50.300 44 184 5.4E-14 T 31-10-2018 DFR86_09070 6ddb41fd6cf767993e5ee51efb669286 232 SUPERFAMILY SSF51556 1 230 9.61E-49 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_09070 6ddb41fd6cf767993e5ee51efb669286 232 Pfam PF01026 TatD related DNase 4 230 9.6E-43 T 31-10-2018 IPR001130 TatD family GO:0016788 DFR86_09070 6ddb41fd6cf767993e5ee51efb669286 232 PIRSF PIRSF005902 1 232 2.9E-45 T 31-10-2018 IPR001130 TatD family GO:0016788 DFR86_09070 6ddb41fd6cf767993e5ee51efb669286 232 Gene3D G3DSA:3.20.20.140 1 232 8.8E-53 T 31-10-2018 DFR86_00995 bbf981ea70da9415c4b3bc50aba71002 120 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 46 102 1.2E-9 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR86_00995 bbf981ea70da9415c4b3bc50aba71002 120 SUPERFAMILY SSF46785 43 106 1.05E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_00995 bbf981ea70da9415c4b3bc50aba71002 120 Gene3D G3DSA:1.10.10.10 26 119 5.4E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_08605 fdf692386cb26db6ff63f90d522bb708 144 PIRSF PIRSF004985 2 140 7.1E-43 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal DFR86_08605 fdf692386cb26db6ff63f90d522bb708 144 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 4 140 34.715 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal DFR86_08605 fdf692386cb26db6ff63f90d522bb708 144 SUPERFAMILY SSF52980 10 133 2.68E-30 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR86_08605 fdf692386cb26db6ff63f90d522bb708 144 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 11 102 5.2E-30 T 31-10-2018 IPR002732 Holliday junction resolvase Hjc DFR86_08605 fdf692386cb26db6ff63f90d522bb708 144 Gene3D G3DSA:3.40.1350.10 1 144 1.2E-51 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 DFR86_08605 fdf692386cb26db6ff63f90d522bb708 144 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 12 141 1.0E-37 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal DFR86_10185 94eee83b11dfb573c88c2eda8aee0c18 198 Gene3D G3DSA:3.40.50.620 1 198 1.2E-39 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_10185 94eee83b11dfb573c88c2eda8aee0c18 198 SUPERFAMILY SSF52402 1 196 3.75E-34 T 31-10-2018 DFR86_10185 94eee83b11dfb573c88c2eda8aee0c18 198 Pfam PF06508 Queuosine biosynthesis protein QueC 2 187 6.6E-28 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 DFR86_07820 93b855d1ee26dc7a8164e1f5550a900c 77 Pfam PF01206 Sulfurtransferase TusA 8 77 5.0E-13 T 31-10-2018 IPR001455 TusA-like domain DFR86_07820 93b855d1ee26dc7a8164e1f5550a900c 77 SUPERFAMILY SSF64307 2 77 2.49E-14 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_07820 93b855d1ee26dc7a8164e1f5550a900c 77 Gene3D G3DSA:3.30.110.40 3 77 7.8E-14 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_02005 491c0d72c54cfd87a73c897bf91ebe2c 618 Pfam PF13183 4Fe-4S dicluster domain 276 333 4.8E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_02005 491c0d72c54cfd87a73c897bf91ebe2c 618 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 279 290 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_02005 491c0d72c54cfd87a73c897bf91ebe2c 618 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 320 331 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_02005 491c0d72c54cfd87a73c897bf91ebe2c 618 Gene3D G3DSA:3.30.70.20 242 337 2.2E-9 T 31-10-2018 DFR86_02005 491c0d72c54cfd87a73c897bf91ebe2c 618 SUPERFAMILY SSF46548 270 340 4.45E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_02645 d38ca18cf2c0620061205ecd383203b7 370 SUPERFAMILY SSF53383 6 367 1.33E-72 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_02645 d38ca18cf2c0620061205ecd383203b7 370 Gene3D G3DSA:3.40.640.10 28 282 5.5E-99 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_02645 d38ca18cf2c0620061205ecd383203b7 370 Pfam PF00266 Aminotransferase class-V 17 359 5.3E-47 T 31-10-2018 IPR000192 Aminotransferase class V domain DFR86_02645 d38ca18cf2c0620061205ecd383203b7 370 Gene3D G3DSA:3.90.1150.10 13 360 5.5E-99 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_06535 916ebe88f75f7d4fa57c68b0ca7d29e2 493 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 4 335 1.2E-60 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR86_06535 916ebe88f75f7d4fa57c68b0ca7d29e2 493 SUPERFAMILY SSF88802 364 458 1.24E-9 T 31-10-2018 DFR86_06535 916ebe88f75f7d4fa57c68b0ca7d29e2 493 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 4 473 1.6E-115 T 31-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 DFR86_06535 916ebe88f75f7d4fa57c68b0ca7d29e2 493 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 4 493 40.89 T 31-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 DFR86_06535 916ebe88f75f7d4fa57c68b0ca7d29e2 493 Gene3D G3DSA:3.20.20.105 1 355 3.9E-95 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR86_06535 916ebe88f75f7d4fa57c68b0ca7d29e2 493 Pfam PF01702 Queuine tRNA-ribosyltransferase 103 329 1.7E-37 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR86_06535 916ebe88f75f7d4fa57c68b0ca7d29e2 493 SUPERFAMILY SSF51713 3 355 1.7E-97 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR86_07095 ec149411b8a84fcb1c1c2c1b50aab9bf 465 Gene3D G3DSA:1.10.10.1100 396 458 4.9E-14 T 31-10-2018 DFR86_07095 ec149411b8a84fcb1c1c2c1b50aab9bf 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 119 3.0E-7 T 31-10-2018 DFR86_07095 ec149411b8a84fcb1c1c2c1b50aab9bf 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 3.0E-7 T 31-10-2018 DFR86_07095 ec149411b8a84fcb1c1c2c1b50aab9bf 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 221 239 3.0E-7 T 31-10-2018 DFR86_07095 ec149411b8a84fcb1c1c2c1b50aab9bf 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 308 3.0E-7 T 31-10-2018 DFR86_07095 ec149411b8a84fcb1c1c2c1b50aab9bf 465 Gene3D G3DSA:3.50.50.60 194 300 9.5E-7 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_07095 ec149411b8a84fcb1c1c2c1b50aab9bf 465 Gene3D G3DSA:3.50.50.60 99 309 9.5E-7 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_07095 ec149411b8a84fcb1c1c2c1b50aab9bf 465 SUPERFAMILY SSF51905 97 237 1.07E-8 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_07095 ec149411b8a84fcb1c1c2c1b50aab9bf 465 Pfam PF04324 BFD-like [2Fe-2S] binding domain 399 449 7.8E-7 T 31-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain DFR86_08645 1d18fc3c5bd3725a595a60a2828163e7 213 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 4 206 1.3E-33 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08645 1d18fc3c5bd3725a595a60a2828163e7 213 Pfam PF01813 ATP synthase subunit D 12 202 3.9E-43 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08645 1d18fc3c5bd3725a595a60a2828163e7 213 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 3 208 22.974 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_05135 a67081bfe6a1fdc5ae4ad803c32d98f1 377 Gene3D G3DSA:1.10.540.10 1 113 6.8E-19 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 DFR86_05135 a67081bfe6a1fdc5ae4ad803c32d98f1 377 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 121 133 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DFR86_05135 a67081bfe6a1fdc5ae4ad803c32d98f1 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 119 213 5.9E-23 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 DFR86_05135 a67081bfe6a1fdc5ae4ad803c32d98f1 377 Gene3D G3DSA:1.20.140.10 233 377 3.9E-42 T 31-10-2018 DFR86_05135 a67081bfe6a1fdc5ae4ad803c32d98f1 377 PIRSF PIRSF016578 2 376 1.3E-17 T 31-10-2018 DFR86_05135 a67081bfe6a1fdc5ae4ad803c32d98f1 377 Gene3D G3DSA:2.40.110.10 118 232 9.8E-34 T 31-10-2018 DFR86_05135 a67081bfe6a1fdc5ae4ad803c32d98f1 377 SUPERFAMILY SSF47203 224 374 1.56E-44 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR86_05135 a67081bfe6a1fdc5ae4ad803c32d98f1 377 SUPERFAMILY SSF56645 4 236 1.09E-54 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR86_05135 a67081bfe6a1fdc5ae4ad803c32d98f1 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 105 1.2E-15 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 DFR86_05135 a67081bfe6a1fdc5ae4ad803c32d98f1 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 373 7.2E-42 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DFR86_09020 9bab87eb79f2ae764e3573042d656965 168 Gene3D G3DSA:3.40.50.300 1 168 5.3E-41 T 31-10-2018 DFR86_09020 9bab87eb79f2ae764e3573042d656965 168 SUPERFAMILY SSF52540 1 167 4.65E-12 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09020 9bab87eb79f2ae764e3573042d656965 168 Pfam PF13207 AAA domain 1 123 1.7E-6 T 31-10-2018 DFR86_04360 c8d57303002096d2f76ece1e71e20598 439 Gene3D G3DSA:3.90.1150.10 8 428 3.3E-151 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_04360 c8d57303002096d2f76ece1e71e20598 439 PIRSF PIRSF000521 15 123 1.0E-11 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_04360 c8d57303002096d2f76ece1e71e20598 439 PIRSF PIRSF000521 117 433 1.2E-26 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_04360 c8d57303002096d2f76ece1e71e20598 439 Gene3D G3DSA:3.40.640.10 57 321 3.3E-151 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_04360 c8d57303002096d2f76ece1e71e20598 439 SUPERFAMILY SSF53383 16 432 3.99E-112 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_04360 c8d57303002096d2f76ece1e71e20598 439 Pfam PF00202 Aminotransferase class-III 21 430 2.7E-95 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_04170 da2b669730616a63f26083e839309625 398 Gene3D G3DSA:1.20.1250.20 205 389 1.1E-11 T 31-10-2018 DFR86_04170 da2b669730616a63f26083e839309625 398 SUPERFAMILY SSF103473 12 385 1.96E-49 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_04170 da2b669730616a63f26083e839309625 398 Pfam PF07690 Major Facilitator Superfamily 26 348 3.5E-25 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_04170 da2b669730616a63f26083e839309625 398 Gene3D G3DSA:1.20.1250.20 5 200 8.7E-28 T 31-10-2018 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 Gene3D G3DSA:1.10.390.60 181 420 8.1E-96 T 31-10-2018 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 Pfam PF01433 Peptidase family M1 domain 189 415 2.9E-85 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 Gene3D G3DSA:2.60.40.1730 1 173 2.7E-45 T 31-10-2018 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 286 298 1.2E-25 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 155 170 1.2E-25 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 267 282 1.2E-25 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 108 123 1.2E-25 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 232 242 1.2E-25 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 SUPERFAMILY SSF63737 3 171 6.54E-41 T 31-10-2018 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 SUPERFAMILY SSF55486 183 426 3.08E-85 T 31-10-2018 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 Pfam PF11838 ERAP1-like C-terminal domain 484 771 9.4E-34 T 31-10-2018 IPR024571 ERAP1-like C-terminal domain DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 Gene3D G3DSA:2.60.40.1910 421 497 2.1E-17 T 31-10-2018 DFR86_02250 fbd89b91a8c2ca049cb58f33358ae071 777 Gene3D G3DSA:1.25.50.20 498 774 3.6E-29 T 31-10-2018 DFR86_00895 ed7c89f8e151f2f10f37e6bbe3584258 591 Pfam PF02543 Carbamoyltransferase N-terminus 11 368 2.3E-51 T 31-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 DFR86_00895 ed7c89f8e151f2f10f37e6bbe3584258 591 SUPERFAMILY SSF53067 21 374 6.15E-12 T 31-10-2018 DFR86_00895 ed7c89f8e151f2f10f37e6bbe3584258 591 Gene3D G3DSA:3.30.420.350 145 362 1.3E-54 T 31-10-2018 DFR86_00895 ed7c89f8e151f2f10f37e6bbe3584258 591 Gene3D G3DSA:3.90.870.20 386 589 6.0E-69 T 31-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily DFR86_00895 ed7c89f8e151f2f10f37e6bbe3584258 591 Gene3D G3DSA:3.30.420.40 1 101 3.5E-20 T 31-10-2018 DFR86_00895 ed7c89f8e151f2f10f37e6bbe3584258 591 Pfam PF16861 Carbamoyltransferase C-terminus 421 590 9.6E-58 T 31-10-2018 IPR031730 Carbamoyltransferase, C-terminal DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 SMART SM00116 74 122 7.0 T 31-10-2018 IPR000644 CBS domain DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 SMART SM00116 6 54 0.29 T 31-10-2018 IPR000644 CBS domain DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 SMART SM00116 203 251 5.1E-7 T 31-10-2018 IPR000644 CBS domain DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 SMART SM00116 138 185 1.0E-6 T 31-10-2018 IPR000644 CBS domain DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 SUPERFAMILY SSF54631 130 252 1.77E-29 T 31-10-2018 DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 Gene3D G3DSA:3.10.580.10 127 267 8.1E-31 T 31-10-2018 DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 Gene3D G3DSA:3.10.580.10 4 126 1.3E-20 T 31-10-2018 DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 Pfam PF00571 CBS domain 196 251 4.6E-12 T 31-10-2018 IPR000644 CBS domain DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 Pfam PF00571 CBS domain 131 181 7.1E-10 T 31-10-2018 IPR000644 CBS domain DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 Pfam PF00571 CBS domain 67 121 7.3E-6 T 31-10-2018 IPR000644 CBS domain DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 Pfam PF00571 CBS domain 8 53 1.1E-4 T 31-10-2018 IPR000644 CBS domain DFR86_02495 bcb1d2bcf2c9d63a85e00470232e5ea1 269 SUPERFAMILY SSF54631 7 126 1.11E-20 T 31-10-2018 DFR86_05100 83f19d536e72df99e2c314f1a5f09e05 267 Gene3D G3DSA:3.40.50.1980 19 137 8.1E-23 T 31-10-2018 DFR86_05100 83f19d536e72df99e2c314f1a5f09e05 267 Gene3D G3DSA:3.40.50.1980 138 265 1.7E-13 T 31-10-2018 DFR86_05100 83f19d536e72df99e2c314f1a5f09e05 267 SUPERFAMILY SSF53807 13 265 1.53E-38 T 31-10-2018 DFR86_05100 83f19d536e72df99e2c314f1a5f09e05 267 Pfam PF01497 Periplasmic binding protein 22 227 9.2E-20 T 31-10-2018 IPR002491 ABC transporter periplasmic binding domain DFR86_08610 2760b1be6f99ed17b9033e1621bbf7cd 518 Gene3D G3DSA:3.40.50.1010 2 119 4.0E-18 T 31-10-2018 DFR86_08610 2760b1be6f99ed17b9033e1621bbf7cd 518 SMART SM00382 248 370 0.0016 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_08610 2760b1be6f99ed17b9033e1621bbf7cd 518 Pfam PF00437 Type II/IV secretion system protein 202 361 3.1E-8 T 31-10-2018 IPR001482 Type II/IV secretion system protein DFR86_08610 2760b1be6f99ed17b9033e1621bbf7cd 518 Gene3D G3DSA:3.40.50.300 229 501 1.3E-19 T 31-10-2018 DFR86_08610 2760b1be6f99ed17b9033e1621bbf7cd 518 SUPERFAMILY SSF52540 126 428 3.85E-28 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08610 2760b1be6f99ed17b9033e1621bbf7cd 518 SUPERFAMILY SSF88723 8 123 1.96E-7 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR86_08610 2760b1be6f99ed17b9033e1621bbf7cd 518 SMART SM00670 5 107 7.1E-6 T 31-10-2018 IPR002716 PIN domain DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 SUPERFAMILY SSF48179 185 281 2.55E-21 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 Gene3D G3DSA:1.10.1040.10 188 294 4.3E-23 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 278 2.6E-24 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 297 362 2.4E-10 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 PIRSF PIRSF000105 293 363 7.1E-7 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 PIRSF PIRSF000105 1 295 7.8E-84 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 10 183 1.4E-59 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 Gene3D G3DSA:3.40.50.720 1 187 6.1E-64 T 31-10-2018 DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 Gene3D G3DSA:1.10.1040.10 295 364 6.6E-21 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 SUPERFAMILY SSF51735 4 182 3.27E-53 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_00570 e468d1ad45ecd7f9de2c25bb17cc2cac 364 SUPERFAMILY SSF48179 298 361 5.7E-12 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_04785 06cf36333c683733b05385c9f6f2e02a 378 Gene3D G3DSA:3.30.70.20 294 362 2.2E-5 T 31-10-2018 DFR86_04785 06cf36333c683733b05385c9f6f2e02a 378 SUPERFAMILY SSF46548 291 375 1.69E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_04785 06cf36333c683733b05385c9f6f2e02a 378 SUPERFAMILY SSF100950 46 281 8.37E-46 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR86_04785 06cf36333c683733b05385c9f6f2e02a 378 Pfam PF13183 4Fe-4S dicluster domain 297 360 2.4E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_04785 06cf36333c683733b05385c9f6f2e02a 378 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 299 310 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_04785 06cf36333c683733b05385c9f6f2e02a 378 Gene3D G3DSA:3.40.50.10420 105 281 7.4E-28 T 31-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily DFR86_04785 06cf36333c683733b05385c9f6f2e02a 378 Pfam PF02589 LUD domain 51 280 3.5E-53 T 31-10-2018 IPR003741 LUD domain DFR86_10665 15024d5f6fdb7e264043c41c8158e69a 325 SUPERFAMILY SSF50022 96 281 2.18E-24 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_10665 15024d5f6fdb7e264043c41c8158e69a 325 TIGRFAM TIGR03171 soxL2: Rieske iron-sulfur protein SoxL2 2 322 7.5E-190 T 31-10-2018 IPR017586 Rieske iron-sulphur protein SoxL2 DFR86_10665 15024d5f6fdb7e264043c41c8158e69a 325 Pfam PF00355 Rieske [2Fe-2S] domain 173 261 8.6E-6 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR86_10665 15024d5f6fdb7e264043c41c8158e69a 325 Gene3D G3DSA:2.102.10.10 93 317 5.5E-55 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_04970 b6e2b0828f4b3570cb5a38c59b9c8a4d 264 SUPERFAMILY SSF51735 1 148 8.07E-27 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_04970 b6e2b0828f4b3570cb5a38c59b9c8a4d 264 Gene3D G3DSA:3.40.50.720 1 152 2.3E-41 T 31-10-2018 DFR86_04970 b6e2b0828f4b3570cb5a38c59b9c8a4d 264 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 252 1.1E-76 T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 DFR86_04970 b6e2b0828f4b3570cb5a38c59b9c8a4d 264 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 210 232 - T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 DFR86_04970 b6e2b0828f4b3570cb5a38c59b9c8a4d 264 Gene3D G3DSA:1.10.3730.10 153 256 2.9E-28 T 31-10-2018 DFR86_04970 b6e2b0828f4b3570cb5a38c59b9c8a4d 264 SUPERFAMILY SSF48179 149 257 2.89E-27 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_04970 b6e2b0828f4b3570cb5a38c59b9c8a4d 264 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 150 251 5.7E-28 T 31-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 DFR86_04970 b6e2b0828f4b3570cb5a38c59b9c8a4d 264 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 94 8.5E-18 T 31-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal DFR86_04970 b6e2b0828f4b3570cb5a38c59b9c8a4d 264 PIRSF PIRSF000193 1 257 3.7E-67 T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 DFR86_04970 b6e2b0828f4b3570cb5a38c59b9c8a4d 264 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 254 23.48 T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 DFR86_09370 2033ca49ca35d12b93810630a67e96fd 246 SUPERFAMILY SSF52540 4 230 2.0E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09370 2033ca49ca35d12b93810630a67e96fd 246 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_09370 2033ca49ca35d12b93810630a67e96fd 246 SMART SM00382 28 222 8.2E-6 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_09370 2033ca49ca35d12b93810630a67e96fd 246 Pfam PF00005 ABC transporter 19 171 9.2E-24 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_09370 2033ca49ca35d12b93810630a67e96fd 246 Gene3D G3DSA:3.40.50.300 1 241 4.2E-59 T 31-10-2018 DFR86_09370 2033ca49ca35d12b93810630a67e96fd 246 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 241 1.8E-90 T 31-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 DFR86_07730 e1d26a0c396aa8a0bfc7412d2bf2c019 382 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 7 369 43.59 T 31-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR86_07730 e1d26a0c396aa8a0bfc7412d2bf2c019 382 Gene3D G3DSA:3.40.50.620 2 258 1.5E-105 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_07730 e1d26a0c396aa8a0bfc7412d2bf2c019 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 255 265 1.2E-21 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR86_07730 e1d26a0c396aa8a0bfc7412d2bf2c019 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 87 103 1.2E-21 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR86_07730 e1d26a0c396aa8a0bfc7412d2bf2c019 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 211 232 1.2E-21 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR86_07730 e1d26a0c396aa8a0bfc7412d2bf2c019 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 159 1.2E-21 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR86_07730 e1d26a0c396aa8a0bfc7412d2bf2c019 382 SUPERFAMILY SSF52374 7 371 2.92E-93 T 31-10-2018 DFR86_07730 e1d26a0c396aa8a0bfc7412d2bf2c019 382 Gene3D G3DSA:1.10.240.10 259 382 3.8E-47 T 31-10-2018 DFR86_07730 e1d26a0c396aa8a0bfc7412d2bf2c019 382 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 74 379 8.9E-86 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR86_07730 e1d26a0c396aa8a0bfc7412d2bf2c019 382 Pfam PF00579 tRNA synthetases class I (W and Y) 75 350 3.2E-26 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_04905 e12aab72c71aeec2f94830ff0f47f418 118 SUPERFAMILY SSF53146 1 85 4.66E-5 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily DFR86_02405 b85ae09ee04b71cc1d68e4a11bab02a2 218 Pfam PF06778 Chlorite dismutase 24 211 1.4E-46 T 31-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase DFR86_02405 b85ae09ee04b71cc1d68e4a11bab02a2 218 SUPERFAMILY SSF54909 2 217 1.93E-55 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR86_02405 b85ae09ee04b71cc1d68e4a11bab02a2 218 Gene3D G3DSA:3.30.70.1100 101 217 6.3E-23 T 31-10-2018 DFR86_06300 56ade06a3bc764a228d6dd9f5d8741fe 169 Gene3D G3DSA:3.60.15.10 4 163 2.3E-7 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_06300 56ade06a3bc764a228d6dd9f5d8741fe 169 SUPERFAMILY SSF56281 19 146 9.68E-7 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_05880 6b2e09617e22563770f5af83b82cf311 95 Pfam PF01998 Protein of unknown function DUF131 21 79 2.6E-9 T 31-10-2018 IPR002849 Protein of unknown function DUF131 DFR86_03290 57c286a36fce5085451de9cbe8e4ef7e 150 Gene3D G3DSA:2.40.50.140 1 118 5.4E-34 T 31-10-2018 DFR86_03290 57c286a36fce5085451de9cbe8e4ef7e 150 SUPERFAMILY SSF50249 3 102 5.43E-28 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_03290 57c286a36fce5085451de9cbe8e4ef7e 150 Pfam PF01336 OB-fold nucleic acid binding domain 15 87 1.8E-8 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 DFR86_01045 9d06117c50319bd9ecfb6912b9e8d62f 390 SUPERFAMILY SSF53901 234 388 7.04E-18 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_01045 9d06117c50319bd9ecfb6912b9e8d62f 390 Pfam PF00108 Thiolase, N-terminal domain 11 227 3.2E-9 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR86_01045 9d06117c50319bd9ecfb6912b9e8d62f 390 SUPERFAMILY SSF53901 10 232 9.82E-33 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_01045 9d06117c50319bd9ecfb6912b9e8d62f 390 Gene3D G3DSA:3.40.47.10 6 390 1.1E-89 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_01045 9d06117c50319bd9ecfb6912b9e8d62f 390 PIRSF PIRSF000429 4 388 1.5E-28 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR86_00835 cd7f1171b122cfbc98c58ff9ad7903e2 375 SUPERFAMILY SSF52540 10 297 7.36E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00835 cd7f1171b122cfbc98c58ff9ad7903e2 375 Pfam PF01637 ATPase domain predominantly from Archaea 13 274 8.5E-15 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR86_00835 cd7f1171b122cfbc98c58ff9ad7903e2 375 Gene3D G3DSA:3.40.50.300 7 233 2.1E-34 T 31-10-2018 DFR86_00835 cd7f1171b122cfbc98c58ff9ad7903e2 375 Gene3D G3DSA:1.10.8.60 234 312 4.0E-16 T 31-10-2018 DFR86_02730 18bf7621618c94e455ddb16673d36be7 389 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3 177 3.5E-65 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_02730 18bf7621618c94e455ddb16673d36be7 389 Gene3D G3DSA:1.10.1040.10 301 389 1.6E-21 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR86_02730 18bf7621618c94e455ddb16673d36be7 389 SUPERFAMILY SSF48179 298 388 5.7E-20 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_02730 18bf7621618c94e455ddb16673d36be7 389 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 298 388 1.1E-18 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_02730 18bf7621618c94e455ddb16673d36be7 389 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 183 277 5.4E-26 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR86_02730 18bf7621618c94e455ddb16673d36be7 389 SUPERFAMILY SSF51735 2 176 3.06E-53 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_02730 18bf7621618c94e455ddb16673d36be7 389 Gene3D G3DSA:1.10.1040.10 185 294 4.5E-26 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR86_02730 18bf7621618c94e455ddb16673d36be7 389 SUPERFAMILY SSF48179 182 283 2.64E-24 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_02730 18bf7621618c94e455ddb16673d36be7 389 Gene3D G3DSA:3.40.50.720 1 184 3.0E-64 T 31-10-2018 DFR86_06550 370b0c22d3011890199f32ce0f12aee3 390 SMART SM00382 166 305 2.2E-24 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_06550 370b0c22d3011890199f32ce0f12aee3 390 SUPERFAMILY SSF52540 128 379 9.46E-73 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06550 370b0c22d3011890199f32ce0f12aee3 390 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 170 303 1.1E-42 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_06550 370b0c22d3011890199f32ce0f12aee3 390 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 16 374 1.3E-170 T 31-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_06550 370b0c22d3011890199f32ce0f12aee3 390 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 1 389 43.505 T 31-10-2018 IPR023501 Proteasome-activating nucleotidase PAN DFR86_06550 370b0c22d3011890199f32ce0f12aee3 390 Gene3D G3DSA:1.10.8.60 304 387 1.0E-24 T 31-10-2018 DFR86_06550 370b0c22d3011890199f32ce0f12aee3 390 ProSitePatterns PS00674 AAA-protein family signature. 273 291 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR86_06550 370b0c22d3011890199f32ce0f12aee3 390 Gene3D G3DSA:3.40.50.300 123 303 7.8E-70 T 31-10-2018 DFR86_06550 370b0c22d3011890199f32ce0f12aee3 390 Gene3D G3DSA:2.40.50.140 18 122 9.7E-25 T 31-10-2018 DFR86_11710 e341020126fa0097d141acf0641e0225 215 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 6 208 4.3E-31 T 31-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 DFR86_11710 e341020126fa0097d141acf0641e0225 215 SUPERFAMILY SSF46785 144 197 1.8E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_11710 e341020126fa0097d141acf0641e0225 215 Gene3D G3DSA:1.10.10.10 123 211 1.1E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 SMART SM01194 1 123 1.9E-36 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 Pfam PF03463 eRF1 domain 1 2 118 6.6E-22 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 Gene3D G3DSA:3.30.420.60 125 241 5.1E-23 T 31-10-2018 DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 SUPERFAMILY SSF53137 124 239 8.72E-9 T 31-10-2018 DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 SUPERFAMILY SSF159065 1 119 1.31E-30 T 31-10-2018 IPR038069 Pelota/DOM34, N-terminal domain DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 SUPERFAMILY SSF55315 235 338 3.18E-23 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 Pfam PF03465 eRF1 domain 3 246 338 1.1E-18 T 31-10-2018 IPR005142 eRF1 domain 3 DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 Gene3D G3DSA:3.30.1330.30 242 339 1.6E-26 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 338 5.1E-65 T 31-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 Gene3D G3DSA:2.30.30.870 1 124 5.3E-36 T 31-10-2018 IPR038069 Pelota/DOM34, N-terminal domain DFR86_05840 4e7205a8d3d169e70d92895fa4ffae44 339 Hamap MF_01853 Protein pelota homolog [pelA]. 2 338 31.513 T 31-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 DFR86_04025 462ece33e0920b8e3db06138fb3186ba 453 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 106 117 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_04025 462ece33e0920b8e3db06138fb3186ba 453 Pfam PF13183 4Fe-4S dicluster domain 34 120 4.5E-11 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_04025 462ece33e0920b8e3db06138fb3186ba 453 Gene3D G3DSA:1.10.1060.10 7 139 2.1E-8 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_04025 462ece33e0920b8e3db06138fb3186ba 453 SUPERFAMILY SSF46548 32 141 1.31E-16 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_09755 2a98db7c3d14b84fe6fb0087b2f1e8da 349 Pfam PF04123 Domain of unknown function (DUF373) 4 332 2.3E-85 T 31-10-2018 IPR007254 Protein of unknown function DUF373 DFR86_03150 4494c625dacb9921c650adbcb20ebf7d 247 SUPERFAMILY SSF54211 23 142 7.36E-9 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_03150 4494c625dacb9921c650adbcb20ebf7d 247 Pfam PF00288 GHMP kinases N terminal domain 77 136 7.6E-6 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR86_03150 4494c625dacb9921c650adbcb20ebf7d 247 PIRSF PIRSF016896 1 232 5.2E-64 T 31-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 DFR86_03150 4494c625dacb9921c650adbcb20ebf7d 247 Gene3D G3DSA:3.30.230.10 22 147 1.9E-5 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR86_02635 0451a645581c476510d8832477348142 155 Gene3D G3DSA:3.40.50.1010 1 122 1.2E-27 T 31-10-2018 DFR86_02635 0451a645581c476510d8832477348142 155 Pfam PF17146 PIN domain of ribonuclease 4 89 8.7E-16 T 31-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 DFR86_02635 0451a645581c476510d8832477348142 155 SMART SM00670 2 103 0.0052 T 31-10-2018 IPR002716 PIN domain DFR86_01200 7c7dd39fe943793b45f6bd50f80f9136 156 Gene3D G3DSA:1.20.120.330 42 155 7.2E-6 T 31-10-2018 DFR86_01200 7c7dd39fe943793b45f6bd50f80f9136 156 Pfam PF05942 Archaeal PaREP1/PaREP8 family 44 146 1.8E-11 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 Pfam PF00330 Aconitase family (aconitate hydratase) 24 406 9.3E-74 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 SUPERFAMILY SSF53732 1 414 1.57E-122 T 31-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 412 2.6E-176 T 31-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 414 46.218 T 31-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 Gene3D G3DSA:3.30.499.10 270 414 1.3E-51 T 31-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 Gene3D G3DSA:3.30.499.20 4 267 5.0E-80 T 31-10-2018 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 ProSitePatterns PS01244 Aconitase family signature 2. 347 360 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 PRINTS PR00415 Aconitase family signature 293 304 1.3E-12 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 PRINTS PR00415 Aconitase family signature 111 124 1.3E-12 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 PRINTS PR00415 Aconitase family signature 347 360 1.3E-12 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 PRINTS PR00415 Aconitase family signature 125 140 1.3E-12 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR86_01665 62c42df2dc094f59a71ca9d6b4986a1d 416 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 412 1.3E-144 T 31-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 DFR86_11285 aeab2b5f299af71a2b6cdca15b76ae09 619 Pfam PF05317 Thermopsin 25 280 1.4E-67 T 31-10-2018 IPR007981 Peptidase A5, thermopsin DFR86_07635 30fb7fc57cdd17094d4a47eb8043132f 529 Gene3D G3DSA:1.20.1730.10 30 519 1.8E-29 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily DFR86_07635 30fb7fc57cdd17094d4a47eb8043132f 529 Pfam PF00474 Sodium:solute symporter family 41 452 5.8E-17 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 Gene3D G3DSA:1.10.240.10 211 355 3.3E-45 T 31-10-2018 DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 SUPERFAMILY SSF52374 3 349 8.44E-75 T 31-10-2018 DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 PIRSF PIRSF006588 1 355 4.8E-126 T 31-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 5 338 5.7E-41 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 3 338 45.787 T 31-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 202 214 3.1E-12 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 152 167 3.1E-12 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 42 64 3.1E-12 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 169 191 3.1E-12 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 Gene3D G3DSA:3.40.50.620 1 209 7.5E-66 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_05820 a5248e69e52f86c551ef24a2dac0cde3 355 Pfam PF00579 tRNA synthetases class I (W and Y) 29 330 4.1E-50 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 Gene3D G3DSA:3.90.1600.10 499 695 3.6E-64 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 Gene3D G3DSA:1.10.287.690 560 620 3.6E-64 T 31-10-2018 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 Gene3D G3DSA:3.30.420.10 227 421 2.0E-169 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 SMART SM00486 224 665 5.3E-96 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 Gene3D G3DSA:3.30.342.10 56 476 2.0E-169 T 31-10-2018 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 SUPERFAMILY SSF53098 48 445 3.04E-77 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 Pfam PF00136 DNA polymerase family B 462 831 2.6E-48 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 Gene3D G3DSA:1.10.132.60 715 874 5.9E-14 T 31-10-2018 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 599 611 1.3E-9 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 651 659 1.3E-9 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 510 523 1.3E-9 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 SUPERFAMILY SSF56672 452 863 1.33E-106 T 31-10-2018 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 Pfam PF03104 DNA polymerase family B, exonuclease domain 87 363 5.0E-27 T 31-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_08705 883f1e7f2f2164baed75bbf1c45102ec 875 ProSitePatterns PS00116 DNA polymerase family B signature. 653 661 - T 31-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_11430 20f64e10180ba878525691c0568949b5 857 SMART SM00471 110 238 3.6E-5 T 31-10-2018 IPR003607 HD/PDEase domain DFR86_11430 20f64e10180ba878525691c0568949b5 857 SUPERFAMILY SSF109604 154 227 3.4E-11 T 31-10-2018 DFR86_11430 20f64e10180ba878525691c0568949b5 857 Gene3D G3DSA:1.10.3210.10 117 247 4.6E-8 T 31-10-2018 DFR86_11430 20f64e10180ba878525691c0568949b5 857 Pfam PF01966 HD domain 116 225 3.8E-10 T 31-10-2018 IPR006674 HD domain DFR86_09465 a9756c0ab333cfbada47154cafbd717b 323 Gene3D G3DSA:3.40.50.720 18 311 1.6E-109 T 31-10-2018 DFR86_09465 a9756c0ab333cfbada47154cafbd717b 323 SUPERFAMILY SSF51735 113 294 1.0E-44 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_09465 a9756c0ab333cfbada47154cafbd717b 323 SUPERFAMILY SSF52283 15 164 1.72E-31 T 31-10-2018 DFR86_09465 a9756c0ab333cfbada47154cafbd717b 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 318 6.2E-36 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 DFR86_09465 a9756c0ab333cfbada47154cafbd717b 323 Gene3D G3DSA:3.40.50.720 106 296 1.6E-109 T 31-10-2018 DFR86_09465 a9756c0ab333cfbada47154cafbd717b 323 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 31-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 DFR86_09465 a9756c0ab333cfbada47154cafbd717b 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 294 5.6E-49 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DFR86_10840 83571a2e61fbeaf4de4e45a89e97eab0 300 Gene3D G3DSA:3.20.20.70 23 253 1.9E-20 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_10840 83571a2e61fbeaf4de4e45a89e97eab0 300 SMART SM00729 25 228 4.2E-16 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_10840 83571a2e61fbeaf4de4e45a89e97eab0 300 SUPERFAMILY SSF102114 8 240 6.54E-29 T 31-10-2018 DFR86_10840 83571a2e61fbeaf4de4e45a89e97eab0 300 Pfam PF04055 Radical SAM superfamily 30 172 2.7E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 Gene3D G3DSA:3.30.960.10 1 123 1.0E-42 T 31-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 SUPERFAMILY SSF53137 125 259 5.23E-39 T 31-10-2018 DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 Gene3D G3DSA:3.30.420.60 124 259 2.3E-44 T 31-10-2018 DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 8 353 39.166 T 31-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 SUPERFAMILY SSF55315 255 353 3.34E-18 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 Pfam PF03465 eRF1 domain 3 264 353 9.6E-16 T 31-10-2018 IPR005142 eRF1 domain 3 DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 Gene3D G3DSA:3.30.1330.30 260 353 5.3E-22 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 1 313 8.0E-126 T 31-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 Pfam PF03464 eRF1 domain 2 127 260 7.3E-43 T 31-10-2018 IPR005141 eRF1 domain 2 DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 SUPERFAMILY SSF55481 1 123 1.31E-38 T 31-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_03400 1745bd980b7c780491ca81dd8d925ca5 353 SMART SM01194 1 122 3.5E-26 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like DFR86_04600 bbb4dc7ccd42b8acc6471129e225e558 146 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 60 121 3.9E-11 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DFR86_04600 bbb4dc7ccd42b8acc6471129e225e558 146 SUPERFAMILY SSF50249 11 127 7.54E-29 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_04600 bbb4dc7ccd42b8acc6471129e225e558 146 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 24 57 6.4E-10 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DFR86_04600 bbb4dc7ccd42b8acc6471129e225e558 146 Gene3D G3DSA:1.10.12.20 1 63 7.5E-12 T 31-10-2018 DFR86_10475 a2a8dcb2314f175737709cd17e9d001f 541 SUPERFAMILY SSF53474 303 540 3.81E-53 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_10475 a2a8dcb2314f175737709cd17e9d001f 541 Pfam PF00326 Prolyl oligopeptidase family 342 540 5.0E-43 T 31-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DFR86_10475 a2a8dcb2314f175737709cd17e9d001f 541 Gene3D G3DSA:3.40.50.1820 295 540 3.8E-56 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_10475 a2a8dcb2314f175737709cd17e9d001f 541 SUPERFAMILY SSF82171 27 276 2.94E-12 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 138 1.8E-52 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.8E-52 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 1.8E-52 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 414 434 1.8E-52 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 165 190 1.8E-52 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 329 350 1.8E-52 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 392 407 1.8E-52 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 252 266 1.8E-52 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 302 1.8E-52 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 SUPERFAMILY SSF55424 332 443 3.78E-28 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.0E-31 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 1.0E-31 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 144 1.0E-31 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 1.0E-31 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 267 1.0E-31 T 31-10-2018 DFR86_08380 6cf451e751d79501caeef65111f18508 449 Gene3D G3DSA:3.50.50.60 138 258 1.2E-94 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_08380 6cf451e751d79501caeef65111f18508 449 PIRSF PIRSF000350 1 445 5.3E-74 T 31-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 DFR86_08380 6cf451e751d79501caeef65111f18508 449 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 315 3.5E-64 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_08380 6cf451e751d79501caeef65111f18508 449 Gene3D G3DSA:3.30.390.30 334 449 2.1E-26 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_08380 6cf451e751d79501caeef65111f18508 449 SUPERFAMILY SSF51905 1 324 1.51E-48 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_08380 6cf451e751d79501caeef65111f18508 449 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 439 6.8E-24 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR86_08380 6cf451e751d79501caeef65111f18508 449 Gene3D G3DSA:3.50.50.60 3 321 1.2E-94 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_04240 bca5be785fd3f639c6e7067d8a858595 413 Gene3D G3DSA:3.20.20.140 50 344 3.7E-97 T 31-10-2018 DFR86_04240 bca5be785fd3f639c6e7067d8a858595 413 SUPERFAMILY SSF51338 1 407 6.23E-26 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04240 bca5be785fd3f639c6e7067d8a858595 413 Pfam PF01979 Amidohydrolase family 47 396 1.8E-21 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_04240 bca5be785fd3f639c6e7067d8a858595 413 SUPERFAMILY SSF51556 50 345 1.94E-53 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_04240 bca5be785fd3f639c6e7067d8a858595 413 Gene3D G3DSA:2.30.40.10 2 408 3.7E-97 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_10960 230de1326ff6c927daa1aeaa05b87cff 488 SUPERFAMILY SSF54631 372 485 2.33E-16 T 31-10-2018 DFR86_10960 230de1326ff6c927daa1aeaa05b87cff 488 SMART SM00116 375 423 0.013 T 31-10-2018 IPR000644 CBS domain DFR86_10960 230de1326ff6c927daa1aeaa05b87cff 488 SMART SM00116 438 486 2.8 T 31-10-2018 IPR000644 CBS domain DFR86_10960 230de1326ff6c927daa1aeaa05b87cff 488 Gene3D G3DSA:3.10.580.10 365 487 3.0E-16 T 31-10-2018 DFR86_10960 230de1326ff6c927daa1aeaa05b87cff 488 Pfam PF00571 CBS domain 378 420 4.7E-8 T 31-10-2018 IPR000644 CBS domain DFR86_10960 230de1326ff6c927daa1aeaa05b87cff 488 Gene3D G3DSA:1.20.1530.20 1 361 4.0E-40 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily DFR86_10960 230de1326ff6c927daa1aeaa05b87cff 488 Pfam PF00999 Sodium/hydrogen exchanger family 12 347 6.2E-32 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DFR86_11070 298606d77823222e79e01e681854a355 83 SUPERFAMILY SSF64307 6 81 3.66E-19 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_11070 298606d77823222e79e01e681854a355 83 Gene3D G3DSA:3.30.110.40 9 81 3.4E-20 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_11070 298606d77823222e79e01e681854a355 83 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 14 38 - T 31-10-2018 IPR001455 TusA-like domain DFR86_11070 298606d77823222e79e01e681854a355 83 Pfam PF01206 Sulfurtransferase TusA 13 81 9.2E-20 T 31-10-2018 IPR001455 TusA-like domain DFR86_06865 aac4a441e18879cb0966a8bf51a30dbb 196 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 191 37.262 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06865 aac4a441e18879cb0966a8bf51a30dbb 196 Gene3D G3DSA:3.30.420.100 1 195 6.8E-59 T 31-10-2018 DFR86_06865 aac4a441e18879cb0966a8bf51a30dbb 196 SUPERFAMILY SSF53137 2 193 7.2E-52 T 31-10-2018 DFR86_06865 aac4a441e18879cb0966a8bf51a30dbb 196 Pfam PF14204 Ribosomal L18 C-terminal region 138 193 6.7E-12 T 31-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06865 aac4a441e18879cb0966a8bf51a30dbb 196 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 100 6.3E-20 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06085 f816a8ebe6344a08e88a5523df369dcf 152 Pfam PF00312 Ribosomal protein S15 72 146 2.9E-13 T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06085 f816a8ebe6344a08e88a5523df369dcf 152 ProSitePatterns PS00362 Ribosomal protein S15 signature. 96 126 - T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06085 f816a8ebe6344a08e88a5523df369dcf 152 Gene3D G3DSA:1.10.287.10 81 149 6.0E-27 T 31-10-2018 DFR86_06085 f816a8ebe6344a08e88a5523df369dcf 152 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 1 147 33.554 T 31-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06085 f816a8ebe6344a08e88a5523df369dcf 152 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 3 58 1.0E-23 T 31-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06085 f816a8ebe6344a08e88a5523df369dcf 152 SUPERFAMILY SSF47060 64 141 7.06E-18 T 31-10-2018 IPR009068 S15/NS1, RNA-binding DFR86_06085 f816a8ebe6344a08e88a5523df369dcf 152 Gene3D G3DSA:1.10.8.1030 34 80 9.4E-20 T 31-10-2018 DFR86_06085 f816a8ebe6344a08e88a5523df369dcf 152 SMART SM01387 68 147 3.6E-13 T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06085 f816a8ebe6344a08e88a5523df369dcf 152 SMART SM01386 1 58 3.4E-30 T 31-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_00600 57e1490955c13b3fd53b0fa0519b03a3 299 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 12 51 5.4E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_00600 57e1490955c13b3fd53b0fa0519b03a3 299 SMART SM00966 9 54 5.8E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_08165 639011041fa25c1f6ab87c539e028015 81 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 28 77 1.5E-11 T 31-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core DFR86_08165 639011041fa25c1f6ab87c539e028015 81 Gene3D G3DSA:1.10.287.1080 1 81 4.9E-25 T 31-10-2018 DFR86_08165 639011041fa25c1f6ab87c539e028015 81 SUPERFAMILY SSF101386 2 80 5.23E-18 T 31-10-2018 DFR86_06630 60c23965fa5c55aa2fcccdb917301836 221 Gene3D G3DSA:2.40.50.140 8 74 3.6E-13 T 31-10-2018 DFR86_06630 60c23965fa5c55aa2fcccdb917301836 221 Pfam PF04919 Protein of unknown function (DUF655) 8 181 3.8E-58 T 31-10-2018 IPR007003 Protein of unknown function DUF655 DFR86_06630 60c23965fa5c55aa2fcccdb917301836 221 SUPERFAMILY SSF160975 8 181 8.76E-63 T 31-10-2018 DFR86_06630 60c23965fa5c55aa2fcccdb917301836 221 Gene3D G3DSA:1.10.150.280 77 173 1.4E-32 T 31-10-2018 DFR86_01390 70312edce53909d470e5c4062523f5a9 227 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 222 1.4E-59 T 31-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 DFR86_01390 70312edce53909d470e5c4062523f5a9 227 Gene3D G3DSA:3.40.1010.10 1 125 1.2E-27 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR86_01390 70312edce53909d470e5c4062523f5a9 227 SUPERFAMILY SSF53790 4 222 4.45E-34 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR86_01390 70312edce53909d470e5c4062523f5a9 227 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 203 3.8E-38 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR86_01390 70312edce53909d470e5c4062523f5a9 227 PIRSF PIRSF036427 1 227 1.2E-62 T 31-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 DFR86_01390 70312edce53909d470e5c4062523f5a9 227 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 31-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR86_01390 70312edce53909d470e5c4062523f5a9 227 Gene3D G3DSA:3.30.950.10 127 225 9.2E-12 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 DFR86_11590 9d3e4efeaa6892d47a6b69224c17283a 74 Gene3D G3DSA:3.40.50.300 1 74 1.2E-6 T 31-10-2018 DFR86_11590 9d3e4efeaa6892d47a6b69224c17283a 74 Pfam PF00271 Helicase conserved C-terminal domain 3 60 8.3E-5 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_11590 9d3e4efeaa6892d47a6b69224c17283a 74 SUPERFAMILY SSF52540 19 69 3.48E-7 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_11325 4441aca55131866b0236290d26460aa7 95 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 12 89 1.4E-12 T 31-10-2018 DFR86_11325 4441aca55131866b0236290d26460aa7 95 SUPERFAMILY SSF54862 21 92 1.45E-18 T 31-10-2018 DFR86_11325 4441aca55131866b0236290d26460aa7 95 Gene3D G3DSA:3.30.70.20 6 89 7.0E-18 T 31-10-2018 DFR86_11325 4441aca55131866b0236290d26460aa7 95 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_11325 4441aca55131866b0236290d26460aa7 95 PIRSF PIRSF036548 1 95 6.4E-21 T 31-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 DFR86_09895 cb22419c286f9bdd7cf655439d96fcc1 288 PIRSF PIRSF000103 1 288 9.7E-72 T 31-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 DFR86_09895 cb22419c286f9bdd7cf655439d96fcc1 288 SUPERFAMILY SSF51735 2 161 7.89E-40 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_09895 cb22419c286f9bdd7cf655439d96fcc1 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 160 8.9E-38 T 31-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 DFR86_09895 cb22419c286f9bdd7cf655439d96fcc1 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 283 2.5E-25 T 31-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DFR86_09895 cb22419c286f9bdd7cf655439d96fcc1 288 Gene3D G3DSA:1.10.1040.10 163 288 3.0E-30 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR86_09895 cb22419c286f9bdd7cf655439d96fcc1 288 SUPERFAMILY SSF48179 161 286 3.85E-30 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_09895 cb22419c286f9bdd7cf655439d96fcc1 288 Gene3D G3DSA:3.40.50.720 1 162 6.0E-42 T 31-10-2018 DFR86_08615 6e8aa97fd0e5d14863bf676a36dd2c97 201 SUPERFAMILY SSF52317 2 199 9.02E-50 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_08615 6e8aa97fd0e5d14863bf676a36dd2c97 201 PIRSF PIRSF005639 1 201 5.5E-69 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR86_08615 6e8aa97fd0e5d14863bf676a36dd2c97 201 Gene3D G3DSA:3.40.50.880 1 201 2.7E-65 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_08615 6e8aa97fd0e5d14863bf676a36dd2c97 201 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 198 34.333 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR86_08615 6e8aa97fd0e5d14863bf676a36dd2c97 201 Pfam PF01174 SNO glutamine amidotransferase family 5 198 2.2E-48 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR86_08615 6e8aa97fd0e5d14863bf676a36dd2c97 201 ProSitePatterns PS01236 PdxT/SNO family family signature. 46 56 - T 31-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR86_08615 6e8aa97fd0e5d14863bf676a36dd2c97 201 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 196 1.8E-59 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR86_01260 904b5103083731d04abf1ef84e3a3f50 186 Pfam PF12007 Protein of unknown function (DUF3501) 2 181 3.4E-54 T 31-10-2018 IPR021890 Protein of unknown function DUF3501 DFR86_05845 7834a28109f7b1ff1fa50b17f917a871 339 SUPERFAMILY SSF102114 27 203 9.03E-20 T 31-10-2018 DFR86_05845 7834a28109f7b1ff1fa50b17f917a871 339 Pfam PF13394 4Fe-4S single cluster domain 31 127 7.2E-7 T 31-10-2018 DFR86_05845 7834a28109f7b1ff1fa50b17f917a871 339 Gene3D G3DSA:3.20.20.70 26 254 7.6E-12 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_05845 7834a28109f7b1ff1fa50b17f917a871 339 Pfam PF04055 Radical SAM superfamily 34 138 3.5E-7 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_08635 df926216c12c2a07d31466351817699c 101 Pfam PF00137 ATP synthase subunit C 37 96 2.4E-14 T 31-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 DFR86_08635 df926216c12c2a07d31466351817699c 101 SUPERFAMILY SSF81333 36 99 1.57E-11 T 31-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily DFR86_08635 df926216c12c2a07d31466351817699c 101 Gene3D G3DSA:1.20.120.610 6 99 1.1E-13 T 31-10-2018 DFR86_08635 df926216c12c2a07d31466351817699c 101 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 48 74 1.9E-5 T 31-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08635 df926216c12c2a07d31466351817699c 101 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 75 98 1.9E-5 T 31-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_00375 688f7f4061e3ba20a5549dbf76df3f7c 635 SUPERFAMILY SSF48208 196 588 1.32E-70 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR86_00375 688f7f4061e3ba20a5549dbf76df3f7c 635 Gene3D G3DSA:1.50.10.10 228 596 5.5E-53 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR86_00375 688f7f4061e3ba20a5549dbf76df3f7c 635 Pfam PF00723 Glycosyl hydrolases family 15 237 279 9.7E-6 T 31-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 DFR86_02060 d3a0fcd67ae02ccf32b311db373dbf86 237 Pfam PF00795 Carbon-nitrogen hydrolase 8 214 9.5E-16 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 DFR86_02060 d3a0fcd67ae02ccf32b311db373dbf86 237 Gene3D G3DSA:3.60.110.10 1 228 1.1E-38 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR86_02060 d3a0fcd67ae02ccf32b311db373dbf86 237 SUPERFAMILY SSF56317 1 217 1.14E-37 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR86_06120 dc00c9ba2f5625b113d4024f25e19b4a 219 Gene3D G3DSA:3.90.870.10 3 218 3.5E-59 T 31-10-2018 DFR86_06120 dc00c9ba2f5625b113d4024f25e19b4a 219 SUPERFAMILY SSF55821 5 215 3.43E-52 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily DFR86_06120 dc00c9ba2f5625b113d4024f25e19b4a 219 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 5 215 6.4E-47 T 31-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_04445 7fb97615e702ee2fe96af98b53500f32 310 SMART SM00382 33 221 2.2E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_04445 7fb97615e702ee2fe96af98b53500f32 310 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_04445 7fb97615e702ee2fe96af98b53500f32 310 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 308 1.4E-14 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_04445 7fb97615e702ee2fe96af98b53500f32 310 Gene3D G3DSA:3.40.50.300 3 310 1.5E-66 T 31-10-2018 DFR86_04445 7fb97615e702ee2fe96af98b53500f32 310 SUPERFAMILY SSF52540 38 296 3.34E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04445 7fb97615e702ee2fe96af98b53500f32 310 Pfam PF00005 ABC transporter 36 174 1.0E-24 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_04445 7fb97615e702ee2fe96af98b53500f32 310 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 290 1.1E-13 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_04670 5d7595f3c5727b85ddd2b5b1b3e4aaa9 462 Pfam PF07690 Major Facilitator Superfamily 18 269 1.1E-23 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_04670 5d7595f3c5727b85ddd2b5b1b3e4aaa9 462 Gene3D G3DSA:1.20.1250.20 10 461 9.9E-63 T 31-10-2018 DFR86_04670 5d7595f3c5727b85ddd2b5b1b3e4aaa9 462 SUPERFAMILY SSF103473 12 446 2.75E-62 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_11525 11dae6f2e31b841ccddc89561639b261 88 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 88 17.214 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 DFR86_11525 11dae6f2e31b841ccddc89561639b261 88 Pfam PF09827 CRISPR associated protein Cas2 3 74 2.3E-17 T 31-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 DFR86_11525 11dae6f2e31b841ccddc89561639b261 88 SUPERFAMILY SSF143430 3 80 2.75E-19 T 31-10-2018 DFR86_11525 11dae6f2e31b841ccddc89561639b261 88 Gene3D G3DSA:3.30.70.240 1 67 6.8E-29 T 31-10-2018 DFR86_11525 11dae6f2e31b841ccddc89561639b261 88 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 3 84 5.0E-17 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 DFR86_08030 a07458c14453b197bcd4df52d2f59e83 233 SUPERFAMILY SSF56281 3 232 1.7E-40 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_08030 a07458c14453b197bcd4df52d2f59e83 233 Pfam PF12706 Beta-lactamase superfamily domain 48 197 5.0E-15 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_08030 a07458c14453b197bcd4df52d2f59e83 233 SMART SM00849 20 206 6.4E-10 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_08030 a07458c14453b197bcd4df52d2f59e83 233 Gene3D G3DSA:3.60.15.10 2 233 9.3E-45 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_01720 cb9031ee94aece8bd6aa3b033b75a959 222 SUPERFAMILY SSF48613 1 207 2.67E-67 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR86_01720 cb9031ee94aece8bd6aa3b033b75a959 222 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 208 2.6E-46 T 31-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 DFR86_01720 cb9031ee94aece8bd6aa3b033b75a959 222 Gene3D G3DSA:1.20.910.10 1 211 1.2E-62 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR86_01720 cb9031ee94aece8bd6aa3b033b75a959 222 Pfam PF03070 TENA/THI-4/PQQC family 7 208 2.4E-43 T 31-10-2018 IPR004305 Thiaminase-2/PQQC DFR86_10050 65779564d8dbdd95f743b6e899562e8b 237 SUPERFAMILY SSF52540 1 212 5.78E-12 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_10050 65779564d8dbdd95f743b6e899562e8b 237 Gene3D G3DSA:3.40.50.300 3 215 2.1E-10 T 31-10-2018 DFR86_10050 65779564d8dbdd95f743b6e899562e8b 237 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 201 6.6E-9 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DFR86_08845 1ac5a9a81842e080d992eb555d8d51d0 390 Gene3D G3DSA:3.60.150.10 1 368 6.0E-133 T 31-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR86_08845 1ac5a9a81842e080d992eb555d8d51d0 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 125 141 - T 31-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR86_08845 1ac5a9a81842e080d992eb555d8d51d0 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 328 344 - T 31-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR86_08845 1ac5a9a81842e080d992eb555d8d51d0 390 TIGRFAM TIGR00033 aroC: chorismate synthase 11 356 1.9E-122 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR86_08845 1ac5a9a81842e080d992eb555d8d51d0 390 PIRSF PIRSF001456 3 374 6.0E-143 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR86_08845 1ac5a9a81842e080d992eb555d8d51d0 390 SUPERFAMILY SSF103263 4 357 6.15E-124 T 31-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR86_08845 1ac5a9a81842e080d992eb555d8d51d0 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 31-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR86_08845 1ac5a9a81842e080d992eb555d8d51d0 390 Hamap MF_00300 Chorismate synthase [aroC]. 10 361 36.003 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR86_08845 1ac5a9a81842e080d992eb555d8d51d0 390 Pfam PF01264 Chorismate synthase 10 353 3.1E-125 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR86_09310 dcdd0ac7d990d6aa3d347e48abe2fef9 431 SUPERFAMILY SSF53383 16 416 1.35E-122 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_09310 dcdd0ac7d990d6aa3d347e48abe2fef9 431 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 219 235 - T 31-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 DFR86_09310 dcdd0ac7d990d6aa3d347e48abe2fef9 431 Pfam PF00464 Serine hydroxymethyltransferase 9 383 2.3E-69 T 31-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 DFR86_09310 dcdd0ac7d990d6aa3d347e48abe2fef9 431 Gene3D G3DSA:3.40.640.10 39 276 1.0E-72 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_09310 dcdd0ac7d990d6aa3d347e48abe2fef9 431 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 412 38.713 T 31-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 DFR86_09310 dcdd0ac7d990d6aa3d347e48abe2fef9 431 PIRSF PIRSF000412 1 424 1.6E-140 T 31-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 DFR86_09310 dcdd0ac7d990d6aa3d347e48abe2fef9 431 Gene3D G3DSA:3.90.1150.10 277 426 1.7E-50 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_10590 3d9a8fc08d4bfb8a0f637ba620cff63e 231 Pfam PF01048 Phosphorylase superfamily 16 221 2.1E-27 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DFR86_10590 3d9a8fc08d4bfb8a0f637ba620cff63e 231 Gene3D G3DSA:3.40.50.1580 1 231 3.0E-52 T 31-10-2018 DFR86_10590 3d9a8fc08d4bfb8a0f637ba620cff63e 231 SUPERFAMILY SSF53167 4 230 1.7E-52 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 DFR86_01215 d0b00fc5cfbbdb5896d70e5ef433f22b 335 SUPERFAMILY SSF63965 138 330 1.22E-45 T 31-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 DFR86_01215 d0b00fc5cfbbdb5896d70e5ef433f22b 335 SUPERFAMILY SSF53800 6 132 2.35E-16 T 31-10-2018 DFR86_01215 d0b00fc5cfbbdb5896d70e5ef433f22b 335 Gene3D G3DSA:3.40.50.10230 137 332 1.2E-45 T 31-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 DFR86_01215 d0b00fc5cfbbdb5896d70e5ef433f22b 335 Pfam PF01903 CbiX 14 124 3.6E-19 T 31-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 DFR86_01215 d0b00fc5cfbbdb5896d70e5ef433f22b 335 Gene3D G3DSA:3.40.50.1400 3 136 3.3E-15 T 31-10-2018 DFR86_01215 d0b00fc5cfbbdb5896d70e5ef433f22b 335 Pfam PF02570 Precorrin-8X methylmutase 146 329 6.9E-42 T 31-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 DFR86_00320 2907c762b936b223659a55cf9c4c24f6 1434 SUPERFAMILY SSF53706 12 824 7.49E-106 T 31-10-2018 DFR86_00320 2907c762b936b223659a55cf9c4c24f6 1434 Gene3D G3DSA:3.40.50.740 42 317 6.5E-29 T 31-10-2018 DFR86_00320 2907c762b936b223659a55cf9c4c24f6 1434 SUPERFAMILY SSF50692 1172 1334 1.18E-13 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR86_00320 2907c762b936b223659a55cf9c4c24f6 1434 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 11 37 7.6E-5 T 31-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal DFR86_00320 2907c762b936b223659a55cf9c4c24f6 1434 Gene3D G3DSA:2.40.40.20 1148 1298 6.5E-8 T 31-10-2018 DFR86_06425 11613ec2986689a649b9a6ac34b8d804 87 Gene3D G3DSA:3.30.70.920 7 79 2.4E-25 T 31-10-2018 DFR86_06425 11613ec2986689a649b9a6ac34b8d804 87 SUPERFAMILY SSF54909 6 82 1.47E-19 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR86_06425 11613ec2986689a649b9a6ac34b8d804 87 Pfam PF01037 Lrp/AsnC ligand binding domain 11 82 1.5E-18 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR86_06740 00c115170c676b1055a39d86aefede23 239 Gene3D G3DSA:3.40.50.1000 11 235 9.3E-45 T 31-10-2018 IPR023214 HAD superfamily DFR86_06740 00c115170c676b1055a39d86aefede23 239 Gene3D G3DSA:1.10.150.520 24 109 9.3E-45 T 31-10-2018 DFR86_06740 00c115170c676b1055a39d86aefede23 239 SUPERFAMILY SSF56784 10 238 4.8E-41 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_06740 00c115170c676b1055a39d86aefede23 239 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 90 206 9.2E-12 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR86_06740 00c115170c676b1055a39d86aefede23 239 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 212 5.7E-22 T 31-10-2018 DFR86_03495 3b48a63fafe359ee3e70184345682fe2 301 Gene3D G3DSA:3.40.50.300 1 227 3.5E-60 T 31-10-2018 DFR86_03495 3b48a63fafe359ee3e70184345682fe2 301 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_03495 3b48a63fafe359ee3e70184345682fe2 301 SUPERFAMILY SSF52540 2 218 2.07E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03495 3b48a63fafe359ee3e70184345682fe2 301 Pfam PF00005 ABC transporter 17 154 3.2E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_03495 3b48a63fafe359ee3e70184345682fe2 301 SMART SM00382 26 212 2.3E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_09225 bb361095bacf5e4e4f0d9a24fdcad127 88 Gene3D G3DSA:3.10.20.10 6 84 2.8E-23 T 31-10-2018 DFR86_09225 bb361095bacf5e4e4f0d9a24fdcad127 88 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 21 65 2.5E-11 T 31-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09225 bb361095bacf5e4e4f0d9a24fdcad127 88 SUPERFAMILY SSF160374 4 81 2.75E-22 T 31-10-2018 DFR86_09225 bb361095bacf5e4e4f0d9a24fdcad127 88 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 9 64 4.0E-20 T 31-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 DFR86_09225 bb361095bacf5e4e4f0d9a24fdcad127 88 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 6 65 18.232 T 31-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_10080 9ada9ddf7f28c578e860b1ec4e3b6c38 138 PRINTS PR01438 Universal stress protein signature 116 138 4.1E-22 T 31-10-2018 IPR006015 Universal stress protein A DFR86_10080 9ada9ddf7f28c578e860b1ec4e3b6c38 138 PRINTS PR01438 Universal stress protein signature 2 20 4.1E-22 T 31-10-2018 IPR006015 Universal stress protein A DFR86_10080 9ada9ddf7f28c578e860b1ec4e3b6c38 138 PRINTS PR01438 Universal stress protein signature 98 110 4.1E-22 T 31-10-2018 IPR006015 Universal stress protein A DFR86_10080 9ada9ddf7f28c578e860b1ec4e3b6c38 138 Gene3D G3DSA:3.40.50.620 1 138 1.5E-41 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_10080 9ada9ddf7f28c578e860b1ec4e3b6c38 138 SUPERFAMILY SSF52402 2 138 5.19E-38 T 31-10-2018 DFR86_10080 9ada9ddf7f28c578e860b1ec4e3b6c38 138 Pfam PF00582 Universal stress protein family 1 138 9.8E-40 T 31-10-2018 IPR006016 UspA DFR86_08525 bfbbbd005f73c69c8d046fe01c014af6 357 Pfam PF00155 Aminotransferase class I and II 31 346 5.9E-44 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR86_08525 bfbbbd005f73c69c8d046fe01c014af6 357 SUPERFAMILY SSF53383 16 351 4.31E-68 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_08525 bfbbbd005f73c69c8d046fe01c014af6 357 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 19 349 4.7E-90 T 31-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 DFR86_08525 bfbbbd005f73c69c8d046fe01c014af6 357 Gene3D G3DSA:3.40.640.10 52 268 1.1E-83 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_08525 bfbbbd005f73c69c8d046fe01c014af6 357 Gene3D G3DSA:3.90.1150.10 27 346 1.1E-83 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_08525 bfbbbd005f73c69c8d046fe01c014af6 357 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 218 227 - T 31-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 DFR86_11180 5bd50984e8caf9af2886e6d11e2124d4 327 Gene3D G3DSA:3.30.70.20 6 79 5.2E-10 T 31-10-2018 DFR86_11180 5bd50984e8caf9af2886e6d11e2124d4 327 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_11180 5bd50984e8caf9af2886e6d11e2124d4 327 SUPERFAMILY SSF46548 9 80 2.41E-19 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_11180 5bd50984e8caf9af2886e6d11e2124d4 327 Pfam PF02754 Cysteine-rich domain 227 308 5.6E-9 T 31-10-2018 IPR004017 Cysteine-rich domain DFR86_11180 5bd50984e8caf9af2886e6d11e2124d4 327 Pfam PF02754 Cysteine-rich domain 124 199 3.5E-5 T 31-10-2018 IPR004017 Cysteine-rich domain DFR86_11180 5bd50984e8caf9af2886e6d11e2124d4 327 Pfam PF13183 4Fe-4S dicluster domain 9 69 2.2E-12 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_11180 5bd50984e8caf9af2886e6d11e2124d4 327 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 55 66 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_08640 5d5f2a5b6ce20e9bf1d3d93665050956 45 ProDom PD052431 CHAIN ION EPSILON HYDROLASE SUL-ATPASE HYDROGEN ATPASE MEMBRANE-ASSOCIATED SYNTHASE G 1 43 0.002 T 31-10-2018 IPR012508 ATPase, A1 complex, epsilon subunit, archaeal GO:0015986|GO:0033178|GO:0042626 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08640 5d5f2a5b6ce20e9bf1d3d93665050956 45 Pfam PF08112 ATP synthase epsilon subunit 2 42 3.4E-7 T 31-10-2018 IPR012508 ATPase, A1 complex, epsilon subunit, archaeal GO:0015986|GO:0033178|GO:0042626 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR86_08060 d256edfc7493f12e51c5a895b879dda6 315 Gene3D G3DSA:3.30.1780.10 17 295 2.0E-57 T 31-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 DFR86_08060 d256edfc7493f12e51c5a895b879dda6 315 PIRSF PIRSF001439 1 309 8.1E-46 T 31-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 DFR86_08060 d256edfc7493f12e51c5a895b879dda6 315 Gene3D G3DSA:3.40.50.720 109 281 2.0E-57 T 31-10-2018 DFR86_08060 d256edfc7493f12e51c5a895b879dda6 315 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 76 299 2.1E-40 T 31-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 DFR86_08060 d256edfc7493f12e51c5a895b879dda6 315 SUPERFAMILY SSF51735 3 307 7.62E-61 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_04900 e89aa56955ca4d41478bf25de2c9f59e 201 Pfam PF03692 Putative zinc- or iron-chelating domain 61 137 4.4E-9 T 31-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein DFR86_01935 ee972d45ecbbd659f72a41d350261cf7 191 SUPERFAMILY SSF53474 4 188 9.87E-17 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_01935 ee972d45ecbbd659f72a41d350261cf7 191 Gene3D G3DSA:3.40.50.1820 4 190 1.7E-18 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_01935 ee972d45ecbbd659f72a41d350261cf7 191 Pfam PF00326 Prolyl oligopeptidase family 52 186 2.2E-8 T 31-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DFR86_04300 6f7dd736cc2dd15433c38273539043b6 297 Pfam PF06675 Protein of unknown function (DUF1177) 48 288 4.3E-85 T 31-10-2018 IPR009561 Protein of unknown function DUF1177 DFR86_03660 d661b932acd22c8877545da0904035de 326 Pfam PF01032 FecCD transport family 11 319 1.0E-68 T 31-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 DFR86_03660 d661b932acd22c8877545da0904035de 326 SUPERFAMILY SSF81345 3 319 1.7E-59 T 31-10-2018 IPR037294 ABC transporter, BtuC-like DFR86_03660 d661b932acd22c8877545da0904035de 326 Gene3D G3DSA:1.10.3470.10 1 321 9.8E-69 T 31-10-2018 IPR037294 ABC transporter, BtuC-like DFR86_06330 f39965e6af2bd0b51abadddfce8858bd 334 Gene3D G3DSA:3.30.470.20 89 332 1.0E-95 T 31-10-2018 DFR86_06330 f39965e6af2bd0b51abadddfce8858bd 334 Pfam PF06973 Domain of unknown function (DUF1297) 151 334 2.0E-75 T 31-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR86_06330 f39965e6af2bd0b51abadddfce8858bd 334 Gene3D G3DSA:3.30.1490.20 117 178 1.0E-95 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_06330 f39965e6af2bd0b51abadddfce8858bd 334 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 1 334 50.243 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR86_06330 f39965e6af2bd0b51abadddfce8858bd 334 Pfam PF06849 Protein of unknown function (DUF1246) 3 120 1.2E-37 T 31-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR86_06330 f39965e6af2bd0b51abadddfce8858bd 334 SUPERFAMILY SSF52440 3 101 1.25E-29 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR86_06330 f39965e6af2bd0b51abadddfce8858bd 334 Gene3D G3DSA:3.40.50.20 1 88 5.1E-26 T 31-10-2018 DFR86_06330 f39965e6af2bd0b51abadddfce8858bd 334 SUPERFAMILY SSF56059 104 334 1.2E-81 T 31-10-2018 DFR86_06330 f39965e6af2bd0b51abadddfce8858bd 334 PIRSF PIRSF004602 1 334 4.4E-134 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR86_06705 12c88c36935cea2813f98493e982a4bb 275 Pfam PF01138 3' exoribonuclease family, domain 1 36 171 7.1E-31 T 31-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR86_06705 12c88c36935cea2813f98493e982a4bb 275 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 7 272 44.681 T 31-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 DFR86_06705 12c88c36935cea2813f98493e982a4bb 275 SUPERFAMILY SSF54211 10 218 9.62E-54 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_06705 12c88c36935cea2813f98493e982a4bb 275 Pfam PF03725 3' exoribonuclease family, domain 2 196 259 3.3E-11 T 31-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR86_06705 12c88c36935cea2813f98493e982a4bb 275 Gene3D G3DSA:3.30.230.70 12 275 1.4E-82 T 31-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR86_06705 12c88c36935cea2813f98493e982a4bb 275 SUPERFAMILY SSF55666 192 273 5.24E-20 T 31-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR86_01015 aacf0c88fdf8b526195d53e4f63071bc 414 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 246 413 4.5E-12 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_04800 3c78bc635bd420d3227c6d23b17220d3 472 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 8 416 1.8E-27 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04800 3c78bc635bd420d3227c6d23b17220d3 472 Gene3D G3DSA:1.20.210.10 4 470 3.9E-35 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04800 3c78bc635bd420d3227c6d23b17220d3 472 SUPERFAMILY SSF81442 8 442 1.96E-26 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04800 3c78bc635bd420d3227c6d23b17220d3 472 PRINTS PR01165 Cytochrome c oxidase subunit I signature 103 115 2.5E-5 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04800 3c78bc635bd420d3227c6d23b17220d3 472 PRINTS PR01165 Cytochrome c oxidase subunit I signature 331 350 2.5E-5 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04800 3c78bc635bd420d3227c6d23b17220d3 472 PRINTS PR01165 Cytochrome c oxidase subunit I signature 206 227 2.5E-5 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_08435 4902bf293ce71680de4cb205aeb27528 289 Gene3D G3DSA:3.20.20.70 1 284 1.8E-62 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_08435 4902bf293ce71680de4cb205aeb27528 289 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 224 244 - T 31-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 DFR86_08435 4902bf293ce71680de4cb205aeb27528 289 SUPERFAMILY SSF51395 2 277 1.1E-55 T 31-10-2018 DFR86_08435 4902bf293ce71680de4cb205aeb27528 289 Pfam PF01180 Dihydroorotate dehydrogenase 2 271 1.0E-43 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 DFR86_08435 4902bf293ce71680de4cb205aeb27528 289 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 2 284 9.1E-59 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 DFR86_08435 4902bf293ce71680de4cb205aeb27528 289 PIRSF PIRSF000164 1 283 7.4E-64 T 31-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 DFR86_06825 c51e78c94841dc8688324a21ee1b452f 126 Pfam PF00467 KOW motif 46 74 3.4E-6 T 31-10-2018 IPR005824 KOW DFR86_06825 c51e78c94841dc8688324a21ee1b452f 126 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 3 116 27.733 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06825 c51e78c94841dc8688324a21ee1b452f 126 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 3 118 1.6E-38 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06825 c51e78c94841dc8688324a21ee1b452f 126 Gene3D G3DSA:2.30.30.30 1 126 1.0E-42 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR86_06825 c51e78c94841dc8688324a21ee1b452f 126 SMART SM00739 43 70 3.1E-5 T 31-10-2018 IPR005824 KOW DFR86_06825 c51e78c94841dc8688324a21ee1b452f 126 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 3 117 3.3E-27 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06825 c51e78c94841dc8688324a21ee1b452f 126 SUPERFAMILY SSF50104 3 112 1.81E-29 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR86_08835 b4f6930e14671ed79f81c6517fafcc83 393 SUPERFAMILY SSF55205 4 390 9.32E-76 T 31-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 DFR86_08835 b4f6930e14671ed79f81c6517fafcc83 393 PIRSF PIRSF000505 54 393 9.0E-90 T 31-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 DFR86_08835 b4f6930e14671ed79f81c6517fafcc83 393 PIRSF PIRSF000505 1 61 7.0E-7 T 31-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 DFR86_08835 b4f6930e14671ed79f81c6517fafcc83 393 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 389 26.458 T 31-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 DFR86_08835 b4f6930e14671ed79f81c6517fafcc83 393 Gene3D G3DSA:3.65.10.10 12 379 5.0E-80 T 31-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 DFR86_08835 b4f6930e14671ed79f81c6517fafcc83 393 ProSitePatterns PS00885 EPSP synthase signature 2. 303 321 - T 31-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 DFR86_08835 b4f6930e14671ed79f81c6517fafcc83 393 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 56 383 2.6E-59 T 31-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 DFR86_08835 b4f6930e14671ed79f81c6517fafcc83 393 Gene3D G3DSA:3.65.10.10 20 207 5.0E-80 T 31-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 DFR86_08835 b4f6930e14671ed79f81c6517fafcc83 393 ProSitePatterns PS00104 EPSP synthase signature 1. 63 77 - T 31-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 DFR86_06220 3a267543f11013ed707f1eeb10b87a08 146 Pfam PF00164 Ribosomal protein S12/S23 33 144 7.3E-49 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06220 3a267543f11013ed707f1eeb10b87a08 146 ProSitePatterns PS00055 Ribosomal protein S12 signature. 62 69 - T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06220 3a267543f11013ed707f1eeb10b87a08 146 Gene3D G3DSA:2.40.50.140 27 146 1.4E-50 T 31-10-2018 DFR86_06220 3a267543f11013ed707f1eeb10b87a08 146 SUPERFAMILY SSF50249 22 144 1.37E-36 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_06220 3a267543f11013ed707f1eeb10b87a08 146 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 146 42.392 T 31-10-2018 IPR022863 Ribosomal protein S12, archaea DFR86_06220 3a267543f11013ed707f1eeb10b87a08 146 PIRSF PIRSF002133 18 146 4.6E-34 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06220 3a267543f11013ed707f1eeb10b87a08 146 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 8 146 1.9E-76 T 31-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_03125 9e0defb97f8c70b923e92a558fc32007 390 Pfam PF12698 ABC-2 family transporter protein 18 378 6.5E-16 T 31-10-2018 DFR86_04625 b077fbc8ffad5dd747669b81f46ca11e 687 SMART SM01008 11 117 2.3E-20 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_04625 b077fbc8ffad5dd747669b81f46ca11e 687 Gene3D G3DSA:3.30.365.10 4 685 1.5E-140 T 31-10-2018 DFR86_04625 b077fbc8ffad5dd747669b81f46ca11e 687 SUPERFAMILY SSF56003 109 683 1.44E-124 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR86_04625 b077fbc8ffad5dd747669b81f46ca11e 687 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 11 117 3.5E-12 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_04625 b077fbc8ffad5dd747669b81f46ca11e 687 SUPERFAMILY SSF54665 4 121 5.5E-25 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR86_04625 b077fbc8ffad5dd747669b81f46ca11e 687 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 133 622 3.1E-107 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR86_05325 ebdbbdb5e8270323340d24e517444b21 143 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 1 122 2.0E-51 T 31-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_05325 ebdbbdb5e8270323340d24e517444b21 143 Gene3D G3DSA:3.30.70.640 1 143 2.2E-60 T 31-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_05325 ebdbbdb5e8270323340d24e517444b21 143 Pfam PF01967 MoaC family 1 140 2.8E-49 T 31-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_05325 ebdbbdb5e8270323340d24e517444b21 143 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 1 141 34.415 T 31-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 DFR86_05325 ebdbbdb5e8270323340d24e517444b21 143 SUPERFAMILY SSF55040 1 140 4.05E-48 T 31-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_02445 a541e804c5b24d30e1b7e9f9ad3a0a19 149 Pfam PF00578 AhpC/TSA family 4 124 7.4E-42 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_02445 a541e804c5b24d30e1b7e9f9ad3a0a19 149 PIRSF PIRSF000239 1 145 2.1E-35 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_02445 a541e804c5b24d30e1b7e9f9ad3a0a19 149 SUPERFAMILY SSF52833 1 145 1.33E-49 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_02445 a541e804c5b24d30e1b7e9f9ad3a0a19 149 Gene3D G3DSA:3.40.30.10 1 148 1.7E-46 T 31-10-2018 DFR86_05500 263986a637f34ab93da76e4c3b61452d 162 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 103 8.9E-25 T 31-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 DFR86_05500 263986a637f34ab93da76e4c3b61452d 162 SUPERFAMILY SSF52540 2 105 7.44E-14 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_05500 263986a637f34ab93da76e4c3b61452d 162 Gene3D G3DSA:3.40.50.300 1 156 7.8E-29 T 31-10-2018 DFR86_05500 263986a637f34ab93da76e4c3b61452d 162 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 127 7.7E-31 T 31-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 DFR86_07190 109fb476160dd98a2b1a892267ac9325 187 SUPERFAMILY SSF81301 9 149 1.77E-10 T 31-10-2018 DFR86_07190 109fb476160dd98a2b1a892267ac9325 187 Pfam PF09970 Nucleotidyl transferase of unknown function (DUF2204) 4 180 2.2E-55 T 31-10-2018 IPR018700 Protein of unknown function DUF2204 DFR86_09200 2a061d735be9d0578a19956ac392dd58 152 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 112 4.0E-41 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09200 2a061d735be9d0578a19956ac392dd58 152 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 29.932 T 31-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 DFR86_09200 2a061d735be9d0578a19956ac392dd58 152 Pfam PF01090 Ribosomal protein S19e 3 138 1.6E-42 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09200 2a061d735be9d0578a19956ac392dd58 152 SUPERFAMILY SSF46785 3 150 1.3E-40 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_09200 2a061d735be9d0578a19956ac392dd58 152 SMART SM01413 3 139 1.3E-62 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09200 2a061d735be9d0578a19956ac392dd58 152 Gene3D G3DSA:1.10.10.2700 1 150 2.0E-43 T 31-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_10575 c34433fd863a4aa5b8874fde571cd601 467 SUPERFAMILY SSF53850 40 458 3.6E-30 T 31-10-2018 DFR86_10575 c34433fd863a4aa5b8874fde571cd601 467 Gene3D G3DSA:3.40.190.10 37 464 4.1E-34 T 31-10-2018 DFR86_10575 c34433fd863a4aa5b8874fde571cd601 467 Pfam PF13416 Bacterial extracellular solute-binding protein 62 385 8.3E-11 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein DFR86_10595 3b3e1fb3b1c9422669de682f4afa4fc6 385 Pfam PF07690 Major Facilitator Superfamily 2 338 2.6E-24 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_10595 3b3e1fb3b1c9422669de682f4afa4fc6 385 Gene3D G3DSA:1.20.1250.20 186 377 2.5E-10 T 31-10-2018 DFR86_10595 3b3e1fb3b1c9422669de682f4afa4fc6 385 SUPERFAMILY SSF103473 2 373 1.11E-37 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_10595 3b3e1fb3b1c9422669de682f4afa4fc6 385 Gene3D G3DSA:1.20.1250.20 1 183 6.2E-15 T 31-10-2018 DFR86_11355 3d77d4aa76e60fbb2203226d174383b4 292 SUPERFAMILY SSF48613 70 278 1.95E-36 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR86_11355 3d77d4aa76e60fbb2203226d174383b4 292 Pfam PF16293 C2H2 type zinc-finger (1 copy) 1 55 2.3E-23 T 31-10-2018 IPR032553 UCP032676, C2H2 type zinc-finger domain DFR86_11355 3d77d4aa76e60fbb2203226d174383b4 292 Pfam PF03070 TENA/THI-4/PQQC family 64 278 9.6E-39 T 31-10-2018 IPR004305 Thiaminase-2/PQQC DFR86_11355 3d77d4aa76e60fbb2203226d174383b4 292 PIRSF PIRSF032676 1 292 1.9E-140 T 31-10-2018 IPR017004 Uncharacterised conserved protein UCP032676, PqqC DFR86_11355 3d77d4aa76e60fbb2203226d174383b4 292 Gene3D G3DSA:1.20.910.10 1 292 1.2E-112 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR86_08515 3e990720290992324f14ada232463f20 229 SUPERFAMILY SSF51366 1 223 1.61E-38 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR86_08515 3e990720290992324f14ada232463f20 229 Gene3D G3DSA:3.20.20.70 1 227 2.0E-51 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_08515 3e990720290992324f14ada232463f20 229 Pfam PF00977 Histidine biosynthesis protein 3 223 4.8E-46 T 31-10-2018 IPR006062 Histidine biosynthesis GO:0000105 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 2.8E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 2.8E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 2.8E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 232 253 2.8E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 2.8E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 2.8E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 59 69 2.8E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 194 210 2.8E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 284 2.8E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR86_01970 1d68b2121b76236993b35080015e7934 329 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 292 2.2E-39 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_01970 1d68b2121b76236993b35080015e7934 329 Gene3D G3DSA:3.50.50.60 8 302 1.3E-91 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_01970 1d68b2121b76236993b35080015e7934 329 SUPERFAMILY SSF51905 1 311 6.89E-42 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_01970 1d68b2121b76236993b35080015e7934 329 Gene3D G3DSA:3.50.50.60 121 243 1.3E-91 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.3E-28 T 31-10-2018 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 3.3E-28 T 31-10-2018 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 3.3E-28 T 31-10-2018 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 3.3E-28 T 31-10-2018 DFR86_01970 1d68b2121b76236993b35080015e7934 329 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 3.3E-28 T 31-10-2018 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 30 223 3.1E-86 T 31-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 Pfam PF00318 Ribosomal protein S2 38 129 9.2E-10 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 Pfam PF00318 Ribosomal protein S2 136 201 6.2E-15 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 Gene3D G3DSA:3.40.50.10490 33 226 3.2E-65 T 31-10-2018 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 34 45 - T 31-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 26 224 47.92 T 31-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 SUPERFAMILY SSF52313 29 218 8.24E-60 T 31-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 PRINTS PR00395 Ribosomal protein S2 signature 34 52 6.9E-25 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 PRINTS PR00395 Ribosomal protein S2 signature 64 73 6.9E-25 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 PRINTS PR00395 Ribosomal protein S2 signature 175 189 6.9E-25 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 PRINTS PR00395 Ribosomal protein S2 signature 154 165 6.9E-25 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 PRINTS PR00395 Ribosomal protein S2 signature 112 129 6.9E-25 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 PRINTS PR00395 Ribosomal protein S2 signature 137 154 6.9E-25 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05760 77a1f69a37a414551e448a1ac6aae8a1 226 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 137 161 - T 31-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 305 319 - T 31-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 SUPERFAMILY SSF56712 9 576 1.83E-138 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 Gene3D G3DSA:1.10.290.10 276 403 4.5E-97 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 Pfam PF01751 Toprim domain 10 138 1.5E-12 T 31-10-2018 IPR006171 TOPRIM domain DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 SMART SM00493 8 130 2.4E-6 T 31-10-2018 IPR006171 TOPRIM domain DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 SMART SM00437 268 526 9.2E-63 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 12 603 3.4E-189 T 31-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 Pfam PF01131 DNA topoisomerase 154 563 3.9E-110 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 SMART SM00436 130 224 4.0E-31 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 Gene3D G3DSA:3.40.50.140 2 153 7.9E-25 T 31-10-2018 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 Gene3D G3DSA:2.70.20.10 218 473 4.5E-97 T 31-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 489 503 2.7E-18 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 310 319 2.7E-18 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 2.7E-18 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 194 212 2.7E-18 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 389 405 2.7E-18 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR86_09450 28332f4c7122a207ae383e4afa01c26c 664 Gene3D G3DSA:1.10.460.10 163 571 4.5E-97 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 DFR86_02515 051f09be241b6b472e41bf5bfef5ffe2 582 SUPERFAMILY SSF52540 315 565 5.31E-11 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_02515 051f09be241b6b472e41bf5bfef5ffe2 582 SUPERFAMILY SSF52540 12 271 1.86E-9 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_02515 051f09be241b6b472e41bf5bfef5ffe2 582 Gene3D G3DSA:3.40.50.300 1 211 4.7E-11 T 31-10-2018 DFR86_09400 a48d9973efbe9896a1766fd77a9843fb 453 PIRSF PIRSF006815 1 447 1.3E-152 T 31-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 DFR86_09400 a48d9973efbe9896a1766fd77a9843fb 453 Pfam PF02347 Glycine cleavage system P-protein 12 442 1.8E-117 T 31-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 DFR86_09400 a48d9973efbe9896a1766fd77a9843fb 453 SUPERFAMILY SSF53383 9 446 3.79E-95 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_09400 a48d9973efbe9896a1766fd77a9843fb 453 Gene3D G3DSA:3.90.1150.10 74 443 2.6E-149 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_09400 a48d9973efbe9896a1766fd77a9843fb 453 Gene3D G3DSA:3.40.640.10 85 354 2.6E-149 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_09400 a48d9973efbe9896a1766fd77a9843fb 453 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 4 446 46.718 T 31-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 DFR86_02805 0ecb03d10bd57c6a89ff9d24864f605c 62 SUPERFAMILY SSF54160 3 61 4.94E-32 T 31-10-2018 IPR016197 Chromo-like domain superfamily DFR86_02805 0ecb03d10bd57c6a89ff9d24864f605c 62 ProDom PD010328 DNA-BINDING METHYLATION DIRECT SEQUENCING 3D-STRUCTURE A 7A 3.1.27.- P2 7D 10 61 3.0E-12 T 31-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 DFR86_02805 0ecb03d10bd57c6a89ff9d24864f605c 62 Pfam PF02294 7kD DNA-binding domain 4 61 7.1E-39 T 31-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 DFR86_02805 0ecb03d10bd57c6a89ff9d24864f605c 62 Gene3D G3DSA:2.40.50.40 2 62 8.7E-35 T 31-10-2018 DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 SUPERFAMILY SSF54631 158 236 1.53E-12 T 31-10-2018 DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 Pfam PF00571 CBS domain 59 112 4.2E-11 T 31-10-2018 IPR000644 CBS domain DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 Pfam PF00571 CBS domain 184 237 6.1E-10 T 31-10-2018 IPR000644 CBS domain DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 Pfam PF00571 CBS domain 3 49 1.1E-8 T 31-10-2018 IPR000644 CBS domain DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 Pfam PF00571 CBS domain 120 173 3.8E-8 T 31-10-2018 IPR000644 CBS domain DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 SUPERFAMILY SSF54631 58 174 1.99E-28 T 31-10-2018 DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 Gene3D G3DSA:3.10.580.10 1 116 6.1E-27 T 31-10-2018 DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 Gene3D G3DSA:3.10.580.10 117 239 4.4E-27 T 31-10-2018 DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 SMART SM00116 127 174 3.0E-4 T 31-10-2018 IPR000644 CBS domain DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 SMART SM00116 10 53 0.0033 T 31-10-2018 IPR000644 CBS domain DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 SMART SM00116 66 113 1.7E-4 T 31-10-2018 IPR000644 CBS domain DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 SMART SM00116 191 238 7.2E-7 T 31-10-2018 IPR000644 CBS domain DFR86_07430 3e24eb03ce964d873f2b8f1bd5065b16 239 SUPERFAMILY SSF54631 1 51 2.83E-10 T 31-10-2018 DFR86_03145 cc190bc2268203f7f34ff4589ecacaff 263 Gene3D G3DSA:3.40.50.12640 14 262 6.2E-102 T 31-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily DFR86_03145 cc190bc2268203f7f34ff4589ecacaff 263 SUPERFAMILY SSF52467 68 233 1.04E-5 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_03145 cc190bc2268203f7f34ff4589ecacaff 263 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 84 259 1.0E-53 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase DFR86_03145 cc190bc2268203f7f34ff4589ecacaff 263 PIRSF PIRSF004853 13 263 1.3E-116 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase DFR86_03145 cc190bc2268203f7f34ff4589ecacaff 263 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 78 252 5.7E-73 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase DFR86_08665 5f471579189399db8bc71bd761f99f2c 100 SUPERFAMILY SSF159468 4 99 2.09E-19 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08665 5f471579189399db8bc71bd761f99f2c 100 Pfam PF01990 ATP synthase (F/14-kDa) subunit 4 92 1.3E-14 T 31-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08665 5f471579189399db8bc71bd761f99f2c 100 Gene3D G3DSA:3.40.50.10580 2 100 1.2E-17 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_03950 3e7dc75f895d3ec541c298d836b2fb3a 165 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 23 156 3.1E-17 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_03950 3e7dc75f895d3ec541c298d836b2fb3a 165 SUPERFAMILY SSF56770 13 161 2.75E-23 T 31-10-2018 DFR86_03950 3e7dc75f895d3ec541c298d836b2fb3a 165 Gene3D G3DSA:3.40.50.700 6 164 2.2E-32 T 31-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily DFR86_02660 93a1c706d3b79630a23dafbca21f0e6c 345 Hamap MF_01086 UPF0284 protein . 1 345 125.392 T 31-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative DFR86_02660 93a1c706d3b79630a23dafbca21f0e6c 345 SUPERFAMILY SSF52733 34 326 9.42E-42 T 31-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 DFR86_02660 93a1c706d3b79630a23dafbca21f0e6c 345 Gene3D G3DSA:3.40.50.10210 13 344 1.6E-111 T 31-10-2018 DFR86_02660 93a1c706d3b79630a23dafbca21f0e6c 345 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 14 327 1.4E-101 T 31-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative DFR86_06955 62c9c78afab59bfcf8c8825c5d8038d2 307 Gene3D G3DSA:1.10.4200.10 35 288 9.0E-42 T 31-10-2018 DFR86_06955 62c9c78afab59bfcf8c8825c5d8038d2 307 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 18 281 1.6E-38 T 31-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 DFR86_01115 748452f0f9bbab56bc10392793135264 240 Gene3D G3DSA:3.30.930.10 1 240 2.7E-47 T 31-10-2018 DFR86_01115 748452f0f9bbab56bc10392793135264 240 SUPERFAMILY SSF55681 1 238 6.89E-50 T 31-10-2018 DFR86_08545 03c60ed8e584b468fade2252f6bbca05 319 SUPERFAMILY SSF52402 26 254 3.4E-33 T 31-10-2018 DFR86_08545 03c60ed8e584b468fade2252f6bbca05 319 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 201 307 3.8E-24 T 31-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 DFR86_08545 03c60ed8e584b468fade2252f6bbca05 319 PIRSF PIRSF004976 1 316 2.8E-87 T 31-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 DFR86_08545 03c60ed8e584b468fade2252f6bbca05 319 Pfam PF01171 PP-loop family 49 185 1.7E-9 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 DFR86_08545 03c60ed8e584b468fade2252f6bbca05 319 Gene3D G3DSA:3.40.50.620 1 315 2.6E-63 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_04825 3bd79973ff93e71cb48095c1a5fe62d2 304 Gene3D G3DSA:3.20.20.70 14 296 1.8E-25 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_04825 3bd79973ff93e71cb48095c1a5fe62d2 304 SUPERFAMILY SSF102114 20 252 8.37E-27 T 31-10-2018 DFR86_04825 3bd79973ff93e71cb48095c1a5fe62d2 304 Pfam PF04055 Radical SAM superfamily 22 183 6.5E-18 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_04825 3bd79973ff93e71cb48095c1a5fe62d2 304 Pfam PF13394 4Fe-4S single cluster domain 27 122 1.5E-7 T 31-10-2018 DFR86_04825 3bd79973ff93e71cb48095c1a5fe62d2 304 SMART SM00729 16 227 0.0034 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_08220 c5c598124bece0c2bd35b344f896cb16 285 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 12 281 5.7E-83 T 31-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 DFR86_08220 c5c598124bece0c2bd35b344f896cb16 285 Gene3D G3DSA:1.10.357.140 18 171 1.9E-12 T 31-10-2018 DFR86_08220 c5c598124bece0c2bd35b344f896cb16 285 Pfam PF01040 UbiA prenyltransferase family 28 267 6.9E-51 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 DFR86_08220 c5c598124bece0c2bd35b344f896cb16 285 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 8 284 16.838 T 31-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 DFR86_11100 ffb3ef3d13fe89615a8f0ba963237e8c 268 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_11100 ffb3ef3d13fe89615a8f0ba963237e8c 268 SUPERFAMILY SSF52540 4 222 1.55E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_11100 ffb3ef3d13fe89615a8f0ba963237e8c 268 Gene3D G3DSA:3.40.50.300 4 231 3.9E-59 T 31-10-2018 DFR86_11100 ffb3ef3d13fe89615a8f0ba963237e8c 268 Pfam PF00005 ABC transporter 20 156 1.6E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_11100 ffb3ef3d13fe89615a8f0ba963237e8c 268 SMART SM00382 28 206 8.6E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_03545 dfb8266bdcd1640673b1cefeaf4f3e80 171 Pfam PF07680 TQO small subunit DoxA 29 157 2.1E-35 T 31-10-2018 IPR011636 Thiosulphate:quinone oxidoreductase small subunit DoxA KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 DFR86_01930 dc0eaf8fb2c2f03f8b6797f17ab2c252 456 Pfam PF00083 Sugar (and other) transporter 14 445 2.5E-43 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR86_01930 dc0eaf8fb2c2f03f8b6797f17ab2c252 456 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_01930 dc0eaf8fb2c2f03f8b6797f17ab2c252 456 SUPERFAMILY SSF103473 3 445 3.27E-60 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_00465 d3db0497fffa22d8d3bf7b44b33c9df8 292 Pfam PF01012 Electron transfer flavoprotein domain 52 145 3.2E-15 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR86_00465 d3db0497fffa22d8d3bf7b44b33c9df8 292 Gene3D G3DSA:3.40.50.1220 161 292 1.1E-46 T 31-10-2018 DFR86_00465 d3db0497fffa22d8d3bf7b44b33c9df8 292 SUPERFAMILY SSF52467 166 285 3.71E-40 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_00465 d3db0497fffa22d8d3bf7b44b33c9df8 292 PIRSF PIRSF000089 36 291 2.2E-78 T 31-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 DFR86_00465 d3db0497fffa22d8d3bf7b44b33c9df8 292 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 166 249 2.3E-30 T 31-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 DFR86_00465 d3db0497fffa22d8d3bf7b44b33c9df8 292 SUPERFAMILY SSF52402 53 198 9.07E-24 T 31-10-2018 DFR86_00465 d3db0497fffa22d8d3bf7b44b33c9df8 292 Gene3D G3DSA:3.40.50.620 1 158 2.3E-16 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_05770 3cacb326122e0622c06b9b561b3fcfbb 140 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 10 140 4.1E-57 T 31-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05770 3cacb326122e0622c06b9b561b3fcfbb 140 Gene3D G3DSA:3.30.230.10 3 140 5.5E-43 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR86_05770 3cacb326122e0622c06b9b561b3fcfbb 140 SUPERFAMILY SSF54211 10 140 4.55E-33 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_05770 3cacb326122e0622c06b9b561b3fcfbb 140 ProSitePatterns PS00360 Ribosomal protein S9 signature. 75 93 - T 31-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 DFR86_05770 3cacb326122e0622c06b9b561b3fcfbb 140 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 10 140 33.118 T 31-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05770 3cacb326122e0622c06b9b561b3fcfbb 140 Pfam PF00380 Ribosomal protein S9/S16 16 140 1.1E-27 T 31-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 DFR86_08245 4c7cd9239eae59223f0c83792d6bbf06 161 Gene3D G3DSA:3.40.1520.10 1 161 1.8E-79 T 31-10-2018 IPR036902 Ta1353-like superfamily DFR86_08245 4c7cd9239eae59223f0c83792d6bbf06 161 SUPERFAMILY SSF103165 2 160 8.63E-73 T 31-10-2018 IPR036902 Ta1353-like superfamily DFR86_08245 4c7cd9239eae59223f0c83792d6bbf06 161 Pfam PF04008 Adenosine specific kinase 7 160 2.8E-76 T 31-10-2018 IPR007153 Adenosine specific kinase DFR86_09595 ae1ff907576e9019367e66d16bea2e34 350 SUPERFAMILY SSF55347 148 332 2.17E-34 T 31-10-2018 DFR86_09595 ae1ff907576e9019367e66d16bea2e34 350 SUPERFAMILY SSF51735 4 176 3.49E-42 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_09595 ae1ff907576e9019367e66d16bea2e34 350 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 4 345 5.5E-143 T 31-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 DFR86_09595 ae1ff907576e9019367e66d16bea2e34 350 PIRSF PIRSF000148 3 350 2.0E-86 T 31-10-2018 DFR86_09595 ae1ff907576e9019367e66d16bea2e34 350 Gene3D G3DSA:3.40.50.720 5 342 7.4E-128 T 31-10-2018 DFR86_09595 ae1ff907576e9019367e66d16bea2e34 350 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 129 1.7E-32 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR86_09595 ae1ff907576e9019367e66d16bea2e34 350 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 330 8.0E-26 T 31-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR86_09595 ae1ff907576e9019367e66d16bea2e34 350 SMART SM00859 5 131 9.8E-35 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR86_09595 ae1ff907576e9019367e66d16bea2e34 350 Gene3D G3DSA:3.30.360.10 150 327 7.4E-128 T 31-10-2018 DFR86_03710 44ffb469b1915783e868c58e0ea73517 646 Gene3D G3DSA:3.40.50.300 227 456 2.8E-23 T 31-10-2018 DFR86_03710 44ffb469b1915783e868c58e0ea73517 646 SMART SM00487 23 203 1.7E-19 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_03710 44ffb469b1915783e868c58e0ea73517 646 Pfam PF00270 DEAD/DEAH box helicase 33 180 4.4E-18 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_03710 44ffb469b1915783e868c58e0ea73517 646 SMART SM00490 266 374 8.9E-17 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_03710 44ffb469b1915783e868c58e0ea73517 646 Pfam PF00271 Helicase conserved C-terminal domain 250 374 3.2E-12 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_03710 44ffb469b1915783e868c58e0ea73517 646 SUPERFAMILY SSF52540 27 387 9.22E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03710 44ffb469b1915783e868c58e0ea73517 646 Gene3D G3DSA:3.40.50.300 18 195 9.8E-26 T 31-10-2018 DFR86_05215 4d0b93ed959eb02d29c224843c5b5765 260 Gene3D G3DSA:3.40.50.720 1 259 4.2E-55 T 31-10-2018 DFR86_05215 4d0b93ed959eb02d29c224843c5b5765 260 SUPERFAMILY SSF51735 6 255 4.3E-62 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_05215 4d0b93ed959eb02d29c224843c5b5765 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 8.0E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_05215 4d0b93ed959eb02d29c224843c5b5765 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 8.0E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_05215 4d0b93ed959eb02d29c224843c5b5765 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.0E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_05215 4d0b93ed959eb02d29c224843c5b5765 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.0E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_05215 4d0b93ed959eb02d29c224843c5b5765 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 8.0E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_05215 4d0b93ed959eb02d29c224843c5b5765 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 8.0E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR86_05215 4d0b93ed959eb02d29c224843c5b5765 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 254 1.6E-45 T 31-10-2018 DFR86_07840 913800ab42797c731d3fd9a7c6b8354a 61 ProDom PD010328 DNA-BINDING METHYLATION DIRECT SEQUENCING 3D-STRUCTURE A 7A 3.1.27.- P2 7D 9 60 4.0E-12 T 31-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 DFR86_07840 913800ab42797c731d3fd9a7c6b8354a 61 SUPERFAMILY SSF54160 1 60 3.02E-32 T 31-10-2018 IPR016197 Chromo-like domain superfamily DFR86_07840 913800ab42797c731d3fd9a7c6b8354a 61 Pfam PF02294 7kD DNA-binding domain 3 60 4.8E-39 T 31-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 DFR86_07840 913800ab42797c731d3fd9a7c6b8354a 61 Gene3D G3DSA:2.40.50.40 1 61 4.5E-35 T 31-10-2018 DFR86_06390 fa98f76adcde4801c7d6a1005b714990 267 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 5 253 1.4E-70 T 31-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase DFR86_06390 fa98f76adcde4801c7d6a1005b714990 267 Gene3D G3DSA:2.40.30.90 163 256 4.5E-20 T 31-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal DFR86_06390 fa98f76adcde4801c7d6a1005b714990 267 SUPERFAMILY SSF102522 3 163 1.7E-53 T 31-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal DFR86_06390 fa98f76adcde4801c7d6a1005b714990 267 SUPERFAMILY SSF101852 167 255 1.11E-18 T 31-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal DFR86_06390 fa98f76adcde4801c7d6a1005b714990 267 Gene3D G3DSA:3.40.50.10790 4 159 1.9E-52 T 31-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal DFR86_06390 fa98f76adcde4801c7d6a1005b714990 267 PIRSF PIRSF006779 1 258 1.0E-87 T 31-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase DFR86_04845 545b4e45a2cd128be265f71acda034cf 356 Pfam PF00534 Glycosyl transferases group 1 201 329 9.3E-17 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR86_04845 545b4e45a2cd128be265f71acda034cf 356 SUPERFAMILY SSF53756 95 355 6.8E-31 T 31-10-2018 DFR86_04845 545b4e45a2cd128be265f71acda034cf 356 Gene3D G3DSA:3.40.50.2000 176 338 1.1E-20 T 31-10-2018 DFR86_02720 7e86a68176b32dfc13c7c2e004f88059 129 SUPERFAMILY SSF54631 1 119 4.42E-33 T 31-10-2018 DFR86_02720 7e86a68176b32dfc13c7c2e004f88059 129 SMART SM00116 73 120 9.5E-9 T 31-10-2018 IPR000644 CBS domain DFR86_02720 7e86a68176b32dfc13c7c2e004f88059 129 SMART SM00116 10 57 2.8E-11 T 31-10-2018 IPR000644 CBS domain DFR86_02720 7e86a68176b32dfc13c7c2e004f88059 129 Gene3D G3DSA:3.10.580.10 1 125 7.3E-38 T 31-10-2018 DFR86_02720 7e86a68176b32dfc13c7c2e004f88059 129 Pfam PF00571 CBS domain 3 57 3.4E-15 T 31-10-2018 IPR000644 CBS domain DFR86_02720 7e86a68176b32dfc13c7c2e004f88059 129 Pfam PF00571 CBS domain 66 119 1.0E-12 T 31-10-2018 IPR000644 CBS domain DFR86_08775 bb0e554525a49e77c877c218659c4abe 386 SUPERFAMILY SSF52833 7 99 4.25E-5 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_08775 bb0e554525a49e77c877c218659c4abe 386 Gene3D G3DSA:1.50.10.20 188 328 7.0E-8 T 31-10-2018 DFR86_08775 bb0e554525a49e77c877c218659c4abe 386 SUPERFAMILY SSF48208 211 319 1.96E-9 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR86_10680 13afea2bd18d912de38ecb28cc48c2f4 262 PRINTS PR00069 Aldo-keto reductase signature 98 116 3.2E-25 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR86_10680 13afea2bd18d912de38ecb28cc48c2f4 262 PRINTS PR00069 Aldo-keto reductase signature 198 222 3.2E-25 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR86_10680 13afea2bd18d912de38ecb28cc48c2f4 262 PRINTS PR00069 Aldo-keto reductase signature 41 65 3.2E-25 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR86_10680 13afea2bd18d912de38ecb28cc48c2f4 262 PRINTS PR00069 Aldo-keto reductase signature 129 146 3.2E-25 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR86_10680 13afea2bd18d912de38ecb28cc48c2f4 262 Pfam PF00248 Aldo/keto reductase family 11 259 2.7E-66 T 31-10-2018 IPR023210 NADP-dependent oxidoreductase domain DFR86_10680 13afea2bd18d912de38ecb28cc48c2f4 262 PIRSF PIRSF000097 2 120 3.2E-22 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR86_10680 13afea2bd18d912de38ecb28cc48c2f4 262 PIRSF PIRSF000097 117 261 4.3E-23 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR86_10680 13afea2bd18d912de38ecb28cc48c2f4 262 SUPERFAMILY SSF51430 11 260 6.15E-81 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR86_10680 13afea2bd18d912de38ecb28cc48c2f4 262 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 31-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 DFR86_10680 13afea2bd18d912de38ecb28cc48c2f4 262 Gene3D G3DSA:3.20.20.100 2 261 1.0E-89 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR86_03320 f56265ac407aec6656799247d4069d4f 566 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 566 1.2E-244 T 31-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_03320 f56265ac407aec6656799247d4069d4f 566 Gene3D G3DSA:3.90.700.10 239 340 2.4E-150 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_03320 f56265ac407aec6656799247d4069d4f 566 Gene3D G3DSA:1.20.58.100 411 528 2.9E-36 T 31-10-2018 DFR86_03320 f56265ac407aec6656799247d4069d4f 566 SUPERFAMILY SSF46977 433 566 2.62E-52 T 31-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_03320 f56265ac407aec6656799247d4069d4f 566 Gene3D G3DSA:4.10.80.40 529 562 2.2E-5 T 31-10-2018 DFR86_03320 f56265ac407aec6656799247d4069d4f 566 Pfam PF00890 FAD binding domain 7 386 3.0E-110 T 31-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_03320 f56265ac407aec6656799247d4069d4f 566 SUPERFAMILY SSF51905 2 415 3.26E-69 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03320 f56265ac407aec6656799247d4069d4f 566 Gene3D G3DSA:3.50.50.60 7 396 2.4E-150 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03320 f56265ac407aec6656799247d4069d4f 566 Pfam PF02910 Fumarate reductase flavoprotein C-term 443 566 3.1E-44 T 31-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_03320 f56265ac407aec6656799247d4069d4f 566 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 41 50 - T 31-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_03320 f56265ac407aec6656799247d4069d4f 566 SUPERFAMILY SSF56425 229 345 3.74E-40 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR86_03320 f56265ac407aec6656799247d4069d4f 566 PIRSF PIRSF000171 1 563 1.7E-54 T 31-10-2018 DFR86_02670 7f02ac242facbaf8d384b9731991a4d7 223 SUPERFAMILY SSF56784 1 202 9.08E-31 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_02670 7f02ac242facbaf8d384b9731991a4d7 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 41 191 6.4E-15 T 31-10-2018 DFR86_02670 7f02ac242facbaf8d384b9731991a4d7 223 Gene3D G3DSA:1.10.150.660 16 94 2.8E-66 T 31-10-2018 DFR86_02670 7f02ac242facbaf8d384b9731991a4d7 223 Gene3D G3DSA:3.40.50.1000 5 212 2.8E-66 T 31-10-2018 IPR023214 HAD superfamily DFR86_03270 a174f113e97c0572f37b2dd2dad1cec3 376 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 373 1.6E-128 T 31-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 DFR86_03270 a174f113e97c0572f37b2dd2dad1cec3 376 PIRSF PIRSF001434 1 376 7.0E-135 T 31-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 DFR86_03270 a174f113e97c0572f37b2dd2dad1cec3 376 Gene3D G3DSA:3.40.640.10 5 239 9.1E-68 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_03270 a174f113e97c0572f37b2dd2dad1cec3 376 Gene3D G3DSA:3.90.1150.10 240 375 9.3E-54 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_03270 a174f113e97c0572f37b2dd2dad1cec3 376 SUPERFAMILY SSF53383 31 374 6.26E-101 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_03850 1d109d9f07990649cf48a14a23b7b149 383 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 244 325 9.9E-17 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_03850 1d109d9f07990649cf48a14a23b7b149 383 Pfam PF07282 Putative transposase DNA-binding domain 298 365 2.6E-21 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_06890 67cfd214824ebf32640ee9b813b34016 195 Pfam PF13207 AAA domain 7 145 8.1E-33 T 31-10-2018 DFR86_06890 67cfd214824ebf32640ee9b813b34016 195 Hamap MF_00234 Adenylate kinase [adkA]. 2 195 45.394 T 31-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 DFR86_06890 67cfd214824ebf32640ee9b813b34016 195 Gene3D G3DSA:3.40.50.300 1 195 3.4E-52 T 31-10-2018 DFR86_06890 67cfd214824ebf32640ee9b813b34016 195 SUPERFAMILY SSF52540 5 192 2.8E-14 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_10975 7e454df1aa1addda62e826f704257f91 287 Pfam PF04055 Radical SAM superfamily 17 174 2.7E-9 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_10975 7e454df1aa1addda62e826f704257f91 287 SMART SM00729 10 215 5.6E-8 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_10975 7e454df1aa1addda62e826f704257f91 287 SUPERFAMILY SSF102114 11 243 5.36E-19 T 31-10-2018 DFR86_10975 7e454df1aa1addda62e826f704257f91 287 Gene3D G3DSA:3.20.20.70 4 227 1.5E-12 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_02785 d121dbd353ace085b5de3379af503c69 168 Gene3D G3DSA:1.25.40.350 3 167 2.4E-55 T 31-10-2018 DFR86_02785 d121dbd353ace085b5de3379af503c69 168 SUPERFAMILY SSF101424 7 163 9.02E-57 T 31-10-2018 IPR036321 Hypothetical protein ST1625 DFR86_02785 d121dbd353ace085b5de3379af503c69 168 Pfam PF09205 Domain of unknown function (DUF1955) 7 163 4.0E-67 T 31-10-2018 IPR015288 Protein of unknown function DUF1955 DFR86_05655 7df66fabc4436eb77cb80caac062ba81 262 SMART SM00852 7 175 1.3E-35 T 31-10-2018 IPR001453 MoaB/Mog domain DFR86_05655 7df66fabc4436eb77cb80caac062ba81 262 Pfam PF00994 Probable molybdopterin binding domain 7 173 4.4E-32 T 31-10-2018 IPR001453 MoaB/Mog domain DFR86_05655 7df66fabc4436eb77cb80caac062ba81 262 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 4 253 41.668 T 31-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea DFR86_05655 7df66fabc4436eb77cb80caac062ba81 262 Gene3D G3DSA:3.40.980.10 5 174 6.4E-49 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR86_05655 7df66fabc4436eb77cb80caac062ba81 262 SUPERFAMILY SSF53218 4 206 3.8E-38 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR86_04200 3adf873c7f3fa56c35c80c7881b459fd 212 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 51 66 - T 31-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR86_04200 3adf873c7f3fa56c35c80c7881b459fd 212 SUPERFAMILY SSF53167 7 207 5.89E-31 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 DFR86_04200 3adf873c7f3fa56c35c80c7881b459fd 212 Gene3D G3DSA:3.40.50.1580 2 210 1.5E-29 T 31-10-2018 DFR86_04200 3adf873c7f3fa56c35c80c7881b459fd 212 Pfam PF01048 Phosphorylase superfamily 28 191 1.9E-14 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DFR86_06860 a8f6ce03aafef838b8a3ceb70c4b28a6 151 Pfam PF01280 Ribosomal protein L19e 4 144 3.3E-43 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06860 a8f6ce03aafef838b8a3ceb70c4b28a6 151 Gene3D G3DSA:1.10.1200.240 58 150 5.1E-19 T 31-10-2018 DFR86_06860 a8f6ce03aafef838b8a3ceb70c4b28a6 151 SMART SM01416 3 147 6.1E-61 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06860 a8f6ce03aafef838b8a3ceb70c4b28a6 151 Gene3D G3DSA:1.10.1650.10 1 56 1.2E-13 T 31-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06860 a8f6ce03aafef838b8a3ceb70c4b28a6 151 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 3 150 22.455 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06860 a8f6ce03aafef838b8a3ceb70c4b28a6 151 SUPERFAMILY SSF48140 4 144 2.48E-41 T 31-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 Gene3D G3DSA:3.30.390.30 328 446 1.8E-36 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 7.2E-58 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 127 136 7.2E-58 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 7.2E-58 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 296 7.2E-58 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 384 399 7.2E-58 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 325 346 7.2E-58 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 426 7.2E-58 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 261 7.2E-58 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.2E-58 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 Gene3D G3DSA:3.50.50.60 6 313 2.4E-100 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 299 1.7E-57 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PIRSF PIRSF000350 1 446 7.5E-119 T 31-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 Gene3D G3DSA:3.50.50.60 136 253 2.4E-100 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 TIGRFAM TIGR02053 MerA: mercury(II) reductase 4 446 5.1E-170 T 31-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 329 430 2.6E-24 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 SUPERFAMILY SSF51905 1 347 1.07E-42 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 2.9E-27 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 2.9E-27 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 2.9E-27 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 2.9E-27 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.9E-27 T 31-10-2018 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 SUPERFAMILY SSF55424 325 445 9.62E-30 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_03650 b6ad7e6287e599d50409cc943646971a 446 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 31-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 DFR86_10740 227e19324acedcbd267effe21246b101 447 Gene3D G3DSA:3.50.50.60 141 252 1.6E-76 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 1.4E-49 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 1.4E-49 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 246 260 1.4E-49 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 422 1.4E-49 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.4E-49 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 1.4E-49 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 1.4E-49 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 323 344 1.4E-49 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 Gene3D G3DSA:3.50.50.60 6 311 1.6E-76 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_10740 227e19324acedcbd267effe21246b101 447 PIRSF PIRSF000350 1 438 3.1E-68 T 31-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 261 4.0E-25 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 4.0E-25 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.0E-25 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 4.0E-25 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 4.0E-25 T 31-10-2018 DFR86_10740 227e19324acedcbd267effe21246b101 447 SUPERFAMILY SSF51905 1 317 8.95E-47 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_10740 227e19324acedcbd267effe21246b101 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 307 9.8E-51 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_10740 227e19324acedcbd267effe21246b101 447 Gene3D G3DSA:3.30.390.30 320 432 1.3E-21 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_10740 227e19324acedcbd267effe21246b101 447 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 427 1.6E-14 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR86_10740 227e19324acedcbd267effe21246b101 447 SUPERFAMILY SSF55424 324 433 3.09E-22 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR86_10740 227e19324acedcbd267effe21246b101 447 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 31-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 DFR86_07025 da9d7f0d2d8dbd38c5c10c333cff0285 87 SMART SM00651 10 77 1.2E-22 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type DFR86_07025 da9d7f0d2d8dbd38c5c10c333cff0285 87 Gene3D G3DSA:2.30.30.100 1 87 4.2E-27 T 31-10-2018 DFR86_07025 da9d7f0d2d8dbd38c5c10c333cff0285 87 SUPERFAMILY SSF50182 8 79 7.3E-21 T 31-10-2018 IPR010920 LSM domain superfamily DFR86_07025 da9d7f0d2d8dbd38c5c10c333cff0285 87 Pfam PF01423 LSM domain 11 76 9.0E-21 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type DFR86_04655 3d4001fb9072c1a522f1f6e79a2173da 315 ProSitePatterns PS00934 Glyoxalase I signature 1. 9 30 - T 31-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 DFR86_04655 3d4001fb9072c1a522f1f6e79a2173da 315 Gene3D G3DSA:3.10.180.10 138 300 1.7E-33 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR86_04655 3d4001fb9072c1a522f1f6e79a2173da 315 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 138 257 2.4E-10 T 31-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DFR86_04655 3d4001fb9072c1a522f1f6e79a2173da 315 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 112 4.7E-9 T 31-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DFR86_04655 3d4001fb9072c1a522f1f6e79a2173da 315 Gene3D G3DSA:3.10.180.10 1 137 7.6E-39 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR86_04655 3d4001fb9072c1a522f1f6e79a2173da 315 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 3 299 4.1E-114 T 31-10-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type DFR86_04655 3d4001fb9072c1a522f1f6e79a2173da 315 SUPERFAMILY SSF54593 1 279 1.01E-41 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR86_00225 3629345c589fab787b95cdad51188002 236 Pfam PF00005 ABC transporter 19 159 8.3E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_00225 3629345c589fab787b95cdad51188002 236 Gene3D G3DSA:3.40.50.300 1 230 2.6E-58 T 31-10-2018 DFR86_00225 3629345c589fab787b95cdad51188002 236 SUPERFAMILY SSF52540 4 215 6.12E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00225 3629345c589fab787b95cdad51188002 236 SMART SM00382 28 204 1.0E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_08755 1284f998c2d0cda743e6b3aaf425922d 160 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 88 140 7.0E-18 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08755 1284f998c2d0cda743e6b3aaf425922d 160 Gene3D G3DSA:3.30.460.80 1 131 3.4E-31 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08755 1284f998c2d0cda743e6b3aaf425922d 160 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 30 151 5.6E-40 T 31-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08755 1284f998c2d0cda743e6b3aaf425922d 160 SUPERFAMILY SSF143243 9 150 3.01E-41 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08755 1284f998c2d0cda743e6b3aaf425922d 160 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 31 151 9.4E-35 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08625 51576ed96f5ac42947f6c52163904194 96 Pfam PF01283 Ribosomal protein S26e 1 92 2.1E-25 T 31-10-2018 IPR000892 Ribosomal protein S26e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_08625 51576ed96f5ac42947f6c52163904194 96 Gene3D G3DSA:3.30.1740.20 1 96 4.1E-26 T 31-10-2018 IPR038551 Ribosomal protein S26e superfamily DFR86_07750 dff491b2c8e1b5478189544845347b24 146 Pfam PF04138 GtrA-like protein 11 145 7.7E-18 T 31-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 DFR86_07000 1bac4802f8ec6d8fd266180825b6c1ee 137 PIRSF PIRSF008210 1 137 2.4E-60 T 31-10-2018 IPR014450 Uncharacterised conserved protein UCP008210 DFR86_07000 1bac4802f8ec6d8fd266180825b6c1ee 137 Pfam PF09921 Uncharacterized protein conserved in archaea (DUF2153) 8 130 7.4E-57 T 31-10-2018 IPR014450 Uncharacterised conserved protein UCP008210 DFR86_10900 7a16a89544eda0c2a4262574d27e241b 89 Pfam PF13237 4Fe-4S dicluster domain 20 71 4.4E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_10900 7a16a89544eda0c2a4262574d27e241b 89 Gene3D G3DSA:3.30.70.20 3 86 8.0E-13 T 31-10-2018 DFR86_10900 7a16a89544eda0c2a4262574d27e241b 89 PIRSF PIRSF036548 2 89 2.9E-18 T 31-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 DFR86_10900 7a16a89544eda0c2a4262574d27e241b 89 SUPERFAMILY SSF54862 6 81 2.02E-18 T 31-10-2018 DFR86_01705 929cd54c253bbb1514672dc9332190bc 276 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 273 2.0E-96 T 31-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 DFR86_01705 929cd54c253bbb1514672dc9332190bc 276 Gene3D G3DSA:3.20.20.70 121 263 9.7E-89 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_01705 929cd54c253bbb1514672dc9332190bc 276 Gene3D G3DSA:3.90.1170.20 13 271 9.7E-89 T 31-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 DFR86_01705 929cd54c253bbb1514672dc9332190bc 276 PIRSF PIRSF006250 2 276 4.1E-92 T 31-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 DFR86_01705 929cd54c253bbb1514672dc9332190bc 276 SUPERFAMILY SSF54675 4 104 3.53E-18 T 31-10-2018 DFR86_01705 929cd54c253bbb1514672dc9332190bc 276 SUPERFAMILY SSF51690 105 273 1.49E-56 T 31-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 DFR86_01705 929cd54c253bbb1514672dc9332190bc 276 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 21 103 4.5E-16 T 31-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 DFR86_01705 929cd54c253bbb1514672dc9332190bc 276 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 105 272 2.9E-60 T 31-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 DFR86_06140 a4e81fda95467ec2321159e459cf32fd 377 Gene3D G3DSA:3.20.20.140 60 327 4.7E-22 T 31-10-2018 DFR86_06140 a4e81fda95467ec2321159e459cf32fd 377 SUPERFAMILY SSF51556 60 324 1.53E-25 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_06140 a4e81fda95467ec2321159e459cf32fd 377 Pfam PF01979 Amidohydrolase family 53 345 2.7E-12 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR86_02545 6939a707ebf0a688ab780fcd34947044 300 Gene3D G3DSA:3.30.9.10 78 259 1.7E-9 T 31-10-2018 DFR86_02545 6939a707ebf0a688ab780fcd34947044 300 Pfam PF01266 FAD dependent oxidoreductase 4 295 7.1E-8 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DFR86_02545 6939a707ebf0a688ab780fcd34947044 300 Gene3D G3DSA:3.50.50.60 112 297 1.7E-9 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_02545 6939a707ebf0a688ab780fcd34947044 300 SUPERFAMILY SSF51905 3 297 8.42E-12 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_00475 f7a8bbac43babb05ab96561ceb5219a5 259 Pfam PF06053 Domain of unknown function (DUF929) 10 248 1.9E-78 T 31-10-2018 IPR009272 Protein of unknown function DUF929 DFR86_08540 47f8943e7bba3e03035679e30cbd23a5 174 SUPERFAMILY SSF89028 1 169 3.79E-55 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR86_08540 47f8943e7bba3e03035679e30cbd23a5 174 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 7 169 3.0E-69 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR86_08540 47f8943e7bba3e03035679e30cbd23a5 174 Pfam PF01923 Cobalamin adenosyltransferase 2 156 2.9E-45 T 31-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR86_08540 47f8943e7bba3e03035679e30cbd23a5 174 Gene3D G3DSA:1.20.1200.10 19 174 1.9E-51 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR86_08540 47f8943e7bba3e03035679e30cbd23a5 174 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 2 169 4.0E-64 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR86_01590 d3720699386bf84bd6cb209362399e96 236 SMART SM00382 28 204 3.2E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_01590 d3720699386bf84bd6cb209362399e96 236 Pfam PF00005 ABC transporter 19 159 5.9E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_01590 d3720699386bf84bd6cb209362399e96 236 Gene3D G3DSA:3.40.50.300 1 232 3.5E-60 T 31-10-2018 DFR86_01590 d3720699386bf84bd6cb209362399e96 236 SUPERFAMILY SSF52540 4 216 7.07E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_02225 e99466971dbff8aa72dd3957011288e4 354 Gene3D G3DSA:3.90.550.10 29 249 8.6E-21 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_02225 e99466971dbff8aa72dd3957011288e4 354 Pfam PF00535 Glycosyl transferase family 2 45 206 9.8E-15 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_02225 e99466971dbff8aa72dd3957011288e4 354 SUPERFAMILY SSF53448 42 306 5.25E-30 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_10155 4d2e7ec62ab55e1abd745321286403a6 411 SUPERFAMILY SSF109604 1 386 2.62E-75 T 31-10-2018 DFR86_10155 4d2e7ec62ab55e1abd745321286403a6 411 SMART SM00471 46 197 2.4E-10 T 31-10-2018 IPR003607 HD/PDEase domain DFR86_10155 4d2e7ec62ab55e1abd745321286403a6 411 Pfam PF01966 HD domain 50 143 1.4E-11 T 31-10-2018 IPR006674 HD domain DFR86_10155 4d2e7ec62ab55e1abd745321286403a6 411 Gene3D G3DSA:1.10.3210.10 1 303 7.1E-78 T 31-10-2018 DFR86_07220 959a19ad3777f08a54d018f2565039a2 348 Gene3D G3DSA:3.40.50.1970 2 155 1.1E-35 T 31-10-2018 DFR86_07220 959a19ad3777f08a54d018f2565039a2 348 PIRSF PIRSF000112 1 344 7.6E-67 T 31-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 DFR86_07220 959a19ad3777f08a54d018f2565039a2 348 Gene3D G3DSA:1.20.1090.10 157 347 5.3E-59 T 31-10-2018 DFR86_07220 959a19ad3777f08a54d018f2565039a2 348 SUPERFAMILY SSF56796 2 334 1.57E-71 T 31-10-2018 DFR86_07220 959a19ad3777f08a54d018f2565039a2 348 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 7 347 44.702 T 31-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 DFR86_07220 959a19ad3777f08a54d018f2565039a2 348 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 269 1.2E-65 T 31-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 DFR86_06805 b88824bc681784a9c1cf92610a70baf5 79 Gene3D G3DSA:1.10.287.310 1 66 5.1E-20 T 31-10-2018 DFR86_06805 b88824bc681784a9c1cf92610a70baf5 79 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 3 62 15.535 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06805 b88824bc681784a9c1cf92610a70baf5 79 TIGRFAM TIGR00012 L29: ribosomal protein uL29 7 62 1.1E-18 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06805 b88824bc681784a9c1cf92610a70baf5 79 SUPERFAMILY SSF46561 3 64 1.05E-17 T 31-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06805 b88824bc681784a9c1cf92610a70baf5 79 ProSitePatterns PS00579 Ribosomal protein L29 signature. 41 55 - T 31-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06805 b88824bc681784a9c1cf92610a70baf5 79 Pfam PF00831 Ribosomal L29 protein 6 62 1.2E-17 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_03580 b201ab3c11b73338d9ebfe37dbca8e77 337 Gene3D G3DSA:1.10.287.70 26 117 4.2E-7 T 31-10-2018 DFR86_03580 b201ab3c11b73338d9ebfe37dbca8e77 337 Gene3D G3DSA:3.40.50.720 125 268 3.8E-21 T 31-10-2018 DFR86_03580 b201ab3c11b73338d9ebfe37dbca8e77 337 Pfam PF02254 TrkA-N domain 131 240 6.8E-14 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 DFR86_03580 b201ab3c11b73338d9ebfe37dbca8e77 337 SUPERFAMILY SSF51735 125 262 1.28E-19 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_03580 b201ab3c11b73338d9ebfe37dbca8e77 337 SUPERFAMILY SSF81324 12 146 1.1E-7 T 31-10-2018 DFR86_09000 fe41ea8e3ac9119bf083bf74ad9b0798 292 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 289 4.3E-88 T 31-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 DFR86_09000 fe41ea8e3ac9119bf083bf74ad9b0798 292 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 2.5E-28 T 31-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 DFR86_09000 fe41ea8e3ac9119bf083bf74ad9b0798 292 Pfam PF00156 Phosphoribosyl transferase domain 150 265 1.7E-16 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR86_09000 fe41ea8e3ac9119bf083bf74ad9b0798 292 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 2 288 35.956 T 31-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 DFR86_09000 fe41ea8e3ac9119bf083bf74ad9b0798 292 Gene3D G3DSA:3.40.50.2020 1 149 7.8E-50 T 31-10-2018 DFR86_09000 fe41ea8e3ac9119bf083bf74ad9b0798 292 SUPERFAMILY SSF53271 84 278 9.04E-38 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR86_09000 fe41ea8e3ac9119bf083bf74ad9b0798 292 SMART SM01400 1 117 2.6E-46 T 31-10-2018 DFR86_09000 fe41ea8e3ac9119bf083bf74ad9b0798 292 Gene3D G3DSA:3.40.50.2020 150 283 7.5E-41 T 31-10-2018 DFR86_07030 9b289e672942aaeaa7ac08f3431d0b7f 404 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 20 398 1.0E-167 T 31-10-2018 DFR86_07030 9b289e672942aaeaa7ac08f3431d0b7f 404 Gene3D G3DSA:3.30.300.10 26 154 5.0E-156 T 31-10-2018 DFR86_07030 9b289e672942aaeaa7ac08f3431d0b7f 404 Gene3D G3DSA:3.30.300.280 157 397 5.0E-156 T 31-10-2018 DFR86_07030 9b289e672942aaeaa7ac08f3431d0b7f 404 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 2 400 3.5E-170 T 31-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 DFR86_07030 9b289e672942aaeaa7ac08f3431d0b7f 404 Gene3D G3DSA:3.30.300.340 14 286 5.0E-156 T 31-10-2018 DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 SUPERFAMILY SSF46785 419 500 7.34E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 Gene3D G3DSA:3.40.50.300 11 202 2.6E-69 T 31-10-2018 DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 Pfam PF00271 Helicase conserved C-terminal domain 246 388 7.9E-9 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 Gene3D G3DSA:1.10.150.20 645 700 6.2E-23 T 31-10-2018 DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 SMART SM00490 299 388 2.0E-18 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 12 699 27.864 T 31-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 SUPERFAMILY SSF52540 37 401 4.74E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 Gene3D G3DSA:3.40.50.300 206 414 6.4E-59 T 31-10-2018 DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 SUPERFAMILY SSF158702 501 697 6.02E-54 T 31-10-2018 DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 Pfam PF00270 DEAD/DEAH box helicase 29 184 2.9E-21 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 SMART SM00487 23 211 3.8E-26 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_01810 26695befcc3dcb88672adfeb5e63300d 705 Gene3D G3DSA:1.10.3380.30 426 643 4.1E-61 T 31-10-2018 DFR86_10410 8230636f2e891ca08895c32a5df939a1 583 SUPERFAMILY SSF69304 131 320 4.18E-10 T 31-10-2018 DFR86_10410 8230636f2e891ca08895c32a5df939a1 583 Gene3D G3DSA:2.140.10.30 128 227 4.5E-7 T 31-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily DFR86_10410 8230636f2e891ca08895c32a5df939a1 583 SUPERFAMILY SSF53474 351 583 1.83E-56 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_10410 8230636f2e891ca08895c32a5df939a1 583 Gene3D G3DSA:3.40.50.1820 343 583 5.1E-64 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_10410 8230636f2e891ca08895c32a5df939a1 583 Pfam PF00326 Prolyl oligopeptidase family 373 583 6.5E-48 T 31-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DFR86_02430 e22b0108fff4b722958051d7dff67120 143 PIRSF PIRSF014422 1 142 8.5E-52 T 31-10-2018 IPR016618 Uncharacterised conserved protein UCP014422 DFR86_02825 2e4ff2050a05e16483cb5df14947b6dc 445 SMART SM00490 336 415 1.9E-13 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_02825 2e4ff2050a05e16483cb5df14947b6dc 445 SUPERFAMILY SSF52540 110 434 1.03E-43 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_02825 2e4ff2050a05e16483cb5df14947b6dc 445 Pfam PF04851 Type III restriction enzyme, res subunit 67 206 2.1E-25 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 DFR86_02825 2e4ff2050a05e16483cb5df14947b6dc 445 SMART SM00487 65 241 2.8E-26 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_02825 2e4ff2050a05e16483cb5df14947b6dc 445 Gene3D G3DSA:3.40.50.300 234 432 1.9E-46 T 31-10-2018 DFR86_02825 2e4ff2050a05e16483cb5df14947b6dc 445 Pfam PF00271 Helicase conserved C-terminal domain 312 414 7.2E-17 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_02825 2e4ff2050a05e16483cb5df14947b6dc 445 Gene3D G3DSA:3.40.50.300 57 233 2.3E-45 T 31-10-2018 DFR86_09105 884a3ff6b0026102a5b4c9a1b9455ec7 169 Gene3D G3DSA:2.160.10.10 1 169 7.2E-63 T 31-10-2018 DFR86_09105 884a3ff6b0026102a5b4c9a1b9455ec7 169 SUPERFAMILY SSF51161 4 167 6.65E-48 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily DFR86_09105 884a3ff6b0026102a5b4c9a1b9455ec7 169 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 44 2.7E-4 T 31-10-2018 IPR001451 Hexapeptide repeat DFR86_09105 884a3ff6b0026102a5b4c9a1b9455ec7 169 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 1.8E-9 T 31-10-2018 IPR001451 Hexapeptide repeat DFR86_09195 d989bd69c319c5c2ff3fa2737699d267 388 PIRSF PIRSF000484 35 387 9.7E-62 T 31-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 DFR86_09195 d989bd69c319c5c2ff3fa2737699d267 388 SUPERFAMILY SSF54675 2 115 7.51E-31 T 31-10-2018 DFR86_09195 d989bd69c319c5c2ff3fa2737699d267 388 Gene3D G3DSA:3.20.20.70 107 295 2.7E-66 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_09195 d989bd69c319c5c2ff3fa2737699d267 388 Gene3D G3DSA:3.90.1170.20 1 106 7.6E-37 T 31-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 DFR86_09195 d989bd69c319c5c2ff3fa2737699d267 388 Gene3D G3DSA:3.20.140.10 344 387 1.6E-5 T 31-10-2018 DFR86_09195 d989bd69c319c5c2ff3fa2737699d267 388 SUPERFAMILY SSF51690 112 383 2.36E-78 T 31-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 DFR86_09195 d989bd69c319c5c2ff3fa2737699d267 388 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 301 3.8E-23 T 31-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 DFR86_00220 4c9bc3c90637e5f92371335985fdf27d 407 Pfam PF13173 AAA domain 42 162 6.1E-32 T 31-10-2018 DFR86_00220 4c9bc3c90637e5f92371335985fdf27d 407 SMART SM00382 40 155 1.4E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_00220 4c9bc3c90637e5f92371335985fdf27d 407 Gene3D G3DSA:3.40.50.300 13 94 5.1E-6 T 31-10-2018 DFR86_00220 4c9bc3c90637e5f92371335985fdf27d 407 SUPERFAMILY SSF52540 18 221 8.26E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00220 4c9bc3c90637e5f92371335985fdf27d 407 Pfam PF13635 Domain of unknown function (DUF4143) 234 349 1.1E-9 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 DFR86_03380 1fb23af84b354d2bfdfac67027f88c84 282 Gene3D G3DSA:1.10.600.10 1 280 5.7E-69 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR86_03380 1fb23af84b354d2bfdfac67027f88c84 282 Pfam PF00348 Polyprenyl synthetase 30 208 1.1E-37 T 31-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 DFR86_03380 1fb23af84b354d2bfdfac67027f88c84 282 SUPERFAMILY SSF48576 21 207 4.11E-43 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR86_03380 1fb23af84b354d2bfdfac67027f88c84 282 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 192 204 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site DFR86_08535 238e954ba947c738246bd17bb0133838 950 Gene3D G3DSA:1.10.730.10 670 786 7.1E-23 T 31-10-2018 DFR86_08535 238e954ba947c738246bd17bb0133838 950 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 11 950 2.8E-282 T 31-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR86_08535 238e954ba947c738246bd17bb0133838 950 SUPERFAMILY SSF50677 206 429 2.3E-35 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR86_08535 238e954ba947c738246bd17bb0133838 950 SUPERFAMILY SSF52374 11 674 4.8E-98 T 31-10-2018 DFR86_08535 238e954ba947c738246bd17bb0133838 950 SUPERFAMILY SSF47323 683 856 2.8E-30 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_08535 238e954ba947c738246bd17bb0133838 950 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 668 1.0E-62 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_08535 238e954ba947c738246bd17bb0133838 950 Gene3D G3DSA:3.90.740.10 204 437 4.4E-264 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR86_08535 238e954ba947c738246bd17bb0133838 950 Pfam PF08264 Anticodon-binding domain of tRNA 702 833 9.1E-26 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 DFR86_08535 238e954ba947c738246bd17bb0133838 950 Gene3D G3DSA:3.40.50.620 12 665 4.4E-264 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_08535 238e954ba947c738246bd17bb0133838 950 Gene3D G3DSA:1.10.10.720 841 898 6.3E-17 T 31-10-2018 DFR86_08535 238e954ba947c738246bd17bb0133838 950 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 9 950 16.473 T 31-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 DFR86_08535 238e954ba947c738246bd17bb0133838 950 Gene3D G3DSA:3.30.2320.20 813 950 6.3E-17 T 31-10-2018 DFR86_02625 cd88b4def38d7ab595e1bcc4f86b2222 354 SUPERFAMILY SSF103473 6 347 1.02E-36 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_02625 cd88b4def38d7ab595e1bcc4f86b2222 354 Pfam PF07690 Major Facilitator Superfamily 6 298 2.6E-28 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_02625 cd88b4def38d7ab595e1bcc4f86b2222 354 Gene3D G3DSA:1.20.1250.20 4 178 5.6E-24 T 31-10-2018 DFR86_02625 cd88b4def38d7ab595e1bcc4f86b2222 354 Gene3D G3DSA:1.20.1250.20 181 351 1.2E-7 T 31-10-2018 DFR86_08955 ffe4114cf33a038f2feee2c113887774 756 Gene3D G3DSA:3.40.50.12610 463 578 5.0E-18 T 31-10-2018 DFR86_08955 ffe4114cf33a038f2feee2c113887774 756 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 44 509 1.2E-17 T 31-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 DFR86_06420 c13900cc6b8725623e48e3faf8263964 431 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 425 31.336 T 31-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 DFR86_06420 c13900cc6b8725623e48e3faf8263964 431 Gene3D G3DSA:2.40.50.1010 253 399 1.6E-29 T 31-10-2018 DFR86_06420 c13900cc6b8725623e48e3faf8263964 431 Gene3D G3DSA:3.30.70.2200 1 155 6.5E-45 T 31-10-2018 DFR86_06420 c13900cc6b8725623e48e3faf8263964 431 Pfam PF08489 Domain of unknown function (DUF1743) 142 254 6.9E-33 T 31-10-2018 IPR013696 Domain of unknown function DUF1743 DFR86_06420 c13900cc6b8725623e48e3faf8263964 431 Gene3D G3DSA:3.90.600.20 156 252 1.6E-29 T 31-10-2018 DFR86_04645 7cb0876b351e8da7b23fa85488c41ec9 152 Pfam PF00578 AhpC/TSA family 4 125 7.6E-34 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_04645 7cb0876b351e8da7b23fa85488c41ec9 152 SUPERFAMILY SSF52833 1 147 1.35E-48 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_04645 7cb0876b351e8da7b23fa85488c41ec9 152 Gene3D G3DSA:3.40.30.10 1 152 2.3E-49 T 31-10-2018 DFR86_04645 7cb0876b351e8da7b23fa85488c41ec9 152 PIRSF PIRSF000239 1 152 7.6E-28 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_08960 66ca74d2c084344a95b9016cf5f323b3 56 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 17.727 T 31-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 DFR86_08960 66ca74d2c084344a95b9016cf5f323b3 56 Gene3D G3DSA:2.20.28.40 1 55 6.7E-23 T 31-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 DFR86_08960 66ca74d2c084344a95b9016cf5f323b3 56 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 50 4.4E-23 T 31-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 DFR86_08960 66ca74d2c084344a95b9016cf5f323b3 56 SUPERFAMILY SSF144210 4 53 1.31E-19 T 31-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 DFR86_07755 05febf4a781544d4d338861a5143dc1a 317 Pfam PF00155 Aminotransferase class I and II 120 265 1.6E-12 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR86_07755 05febf4a781544d4d338861a5143dc1a 317 Gene3D G3DSA:3.40.640.10 28 225 6.4E-56 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_07755 05febf4a781544d4d338861a5143dc1a 317 SUPERFAMILY SSF53383 11 310 4.87E-39 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_07755 05febf4a781544d4d338861a5143dc1a 317 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 179 188 - T 31-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 DFR86_07755 05febf4a781544d4d338861a5143dc1a 317 Gene3D G3DSA:3.90.1150.10 18 304 6.4E-56 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_01245 4008f7a1a23cce4e43ab6c07bae9fcbc 700 Pfam PF00384 Molybdopterin oxidoreductase 46 483 4.5E-38 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_01245 4008f7a1a23cce4e43ab6c07bae9fcbc 700 SUPERFAMILY SSF53706 2 555 1.44E-113 T 31-10-2018 DFR86_01245 4008f7a1a23cce4e43ab6c07bae9fcbc 700 Gene3D G3DSA:2.40.40.20 555 700 2.1E-33 T 31-10-2018 DFR86_01245 4008f7a1a23cce4e43ab6c07bae9fcbc 700 Gene3D G3DSA:2.20.25.90 1 48 6.1E-7 T 31-10-2018 DFR86_01245 4008f7a1a23cce4e43ab6c07bae9fcbc 700 SUPERFAMILY SSF50692 532 697 7.01E-27 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR86_01245 4008f7a1a23cce4e43ab6c07bae9fcbc 700 Pfam PF01568 Molydopterin dinucleotide binding domain 571 686 3.1E-15 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 Gene3D G3DSA:1.10.472.170 1 189 1.9E-47 T 31-10-2018 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 SMART SM00385 201 282 6.5E-4 T 31-10-2018 IPR013763 Cyclin-like DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 SUPERFAMILY SSF47954 197 288 6.8E-22 T 31-10-2018 IPR036915 Cyclin-like superfamily DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 SUPERFAMILY SSF47954 105 188 2.21E-14 T 31-10-2018 IPR036915 Cyclin-like superfamily DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 Gene3D G3DSA:1.10.472.10 198 290 1.0E-20 T 31-10-2018 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 SUPERFAMILY SSF57783 1 45 3.68E-16 T 31-10-2018 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 PRINTS PR00685 Transcription initiation factor IIB signature 37 50 4.9E-36 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 PRINTS PR00685 Transcription initiation factor IIB signature 236 252 4.9E-36 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 PRINTS PR00685 Transcription initiation factor IIB signature 268 282 4.9E-36 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 PRINTS PR00685 Transcription initiation factor IIB signature 15 35 4.9E-36 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 PRINTS PR00685 Transcription initiation factor IIB signature 202 220 4.9E-36 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 PRINTS PR00685 Transcription initiation factor IIB signature 50 71 4.9E-36 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 PRINTS PR00685 Transcription initiation factor IIB signature 148 167 4.9E-36 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 Pfam PF00382 Transcription factor TFIIB repeat 112 175 1.1E-5 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 Pfam PF00382 Transcription factor TFIIB repeat 203 273 2.2E-11 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 DFR86_09740 3a5de86f8fce3cd7e2d74a37f4a92ad8 290 Pfam PF08271 TFIIB zinc-binding 1 42 6.0E-19 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type DFR86_06475 2578c5e87d816c08ded39a877314a32b 383 SUPERFAMILY SSF111249 2 362 2.75E-171 T 31-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 DFR86_06475 2578c5e87d816c08ded39a877314a32b 383 Pfam PF01950 Fructose-1,6-bisphosphatase 2 362 4.0E-181 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 DFR86_06475 2578c5e87d816c08ded39a877314a32b 383 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 1 362 60.144 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 DFR86_06475 2578c5e87d816c08ded39a877314a32b 383 PIRSF PIRSF015647 1 373 1.7E-184 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 DFR86_06475 2578c5e87d816c08ded39a877314a32b 383 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 1 363 0.0 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 DFR86_03180 baf07ad253f7021e8d7d3e5a2a85f9c2 171 Gene3D G3DSA:3.90.80.10 1 171 1.3E-69 T 31-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 DFR86_03180 baf07ad253f7021e8d7d3e5a2a85f9c2 171 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 62 68 - T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 DFR86_03180 baf07ad253f7021e8d7d3e5a2a85f9c2 171 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 11 170 37.945 T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 DFR86_03180 baf07ad253f7021e8d7d3e5a2a85f9c2 171 Pfam PF00719 Inorganic pyrophosphatase 16 168 1.7E-55 T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 DFR86_03180 baf07ad253f7021e8d7d3e5a2a85f9c2 171 SUPERFAMILY SSF50324 5 170 7.85E-65 T 31-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 DFR86_01980 f547e3626accf783a05b411243154942 356 Pfam PF00534 Glycosyl transferases group 1 180 304 1.2E-17 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR86_01980 f547e3626accf783a05b411243154942 356 Gene3D G3DSA:3.40.50.2000 172 332 1.3E-24 T 31-10-2018 DFR86_01980 f547e3626accf783a05b411243154942 356 SUPERFAMILY SSF53756 18 355 6.28E-33 T 31-10-2018 DFR86_04975 db0bb5df135f6c9e962d892687347ad5 49 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 45 7.3E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_04975 db0bb5df135f6c9e962d892687347ad5 49 SUPERFAMILY SSF89447 1 40 4.01E-10 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR86_04975 db0bb5df135f6c9e962d892687347ad5 49 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 45 1.2E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_04975 db0bb5df135f6c9e962d892687347ad5 49 SMART SM00966 4 49 5.0E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_04975 db0bb5df135f6c9e962d892687347ad5 49 Gene3D G3DSA:2.10.260.10 1 46 4.6E-15 T 31-10-2018 DFR86_03500 d558166a5f2ced1c9aa9fc0a17f7f0c2 251 Pfam PF07885 Ion channel 13 91 1.1E-14 T 31-10-2018 IPR013099 Potassium channel domain DFR86_03500 d558166a5f2ced1c9aa9fc0a17f7f0c2 251 SUPERFAMILY SSF51735 116 245 5.69E-11 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_03500 d558166a5f2ced1c9aa9fc0a17f7f0c2 251 SUPERFAMILY SSF81324 6 96 2.75E-22 T 31-10-2018 DFR86_03500 d558166a5f2ced1c9aa9fc0a17f7f0c2 251 Gene3D G3DSA:3.40.50.720 111 249 1.3E-15 T 31-10-2018 DFR86_03500 d558166a5f2ced1c9aa9fc0a17f7f0c2 251 Pfam PF02254 TrkA-N domain 117 224 2.3E-12 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 DFR86_03500 d558166a5f2ced1c9aa9fc0a17f7f0c2 251 Gene3D G3DSA:1.10.287.70 4 108 8.6E-19 T 31-10-2018 DFR86_00200 0b17729beded3b34fec97f86be411db9 533 Pfam PF01935 Domain of unknown function DUF87 156 384 5.4E-12 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR86_00200 0b17729beded3b34fec97f86be411db9 533 SUPERFAMILY SSF52540 124 513 3.28E-28 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00200 0b17729beded3b34fec97f86be411db9 533 Gene3D G3DSA:3.40.50.300 139 257 3.3E-10 T 31-10-2018 DFR86_00200 0b17729beded3b34fec97f86be411db9 533 SMART SM00382 178 489 1.1E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_00200 0b17729beded3b34fec97f86be411db9 533 Gene3D G3DSA:3.40.50.300 336 528 7.3E-19 T 31-10-2018 DFR86_02500 5aaf49a075cf33c7af454c16d839f87d 98 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 4 97 3.7E-23 T 31-10-2018 IPR002767 Thiamine-binding protein DFR86_02500 5aaf49a075cf33c7af454c16d839f87d 98 SUPERFAMILY SSF89957 1 96 3.66E-23 T 31-10-2018 IPR029756 MTH1187/YkoF-like DFR86_02500 5aaf49a075cf33c7af454c16d839f87d 98 Pfam PF01910 Thiamine-binding protein 5 95 5.9E-25 T 31-10-2018 IPR002767 Thiamine-binding protein DFR86_02500 5aaf49a075cf33c7af454c16d839f87d 98 Gene3D G3DSA:3.30.70.930 3 98 1.3E-24 T 31-10-2018 IPR029756 MTH1187/YkoF-like DFR86_06365 bc55758164a49710e3b6b6f09a84fa6c 173 Gene3D G3DSA:3.30.428.10 1 170 3.4E-56 T 31-10-2018 IPR036265 HIT-like superfamily DFR86_06365 bc55758164a49710e3b6b6f09a84fa6c 173 SUPERFAMILY SSF54197 1 157 2.94E-42 T 31-10-2018 IPR036265 HIT-like superfamily DFR86_06365 bc55758164a49710e3b6b6f09a84fa6c 173 Pfam PF01230 HIT domain 39 130 7.4E-12 T 31-10-2018 IPR001310 Histidine triad (HIT) protein DFR86_09460 fa364b579a0a9e0ddf5c18cd1c960d61 371 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 176 196 - T 31-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site DFR86_09460 fa364b579a0a9e0ddf5c18cd1c960d61 371 Gene3D G3DSA:3.40.640.10 11 251 1.1E-91 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_09460 fa364b579a0a9e0ddf5c18cd1c960d61 371 SUPERFAMILY SSF53383 2 348 8.87E-77 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_09460 fa364b579a0a9e0ddf5c18cd1c960d61 371 PIRSF PIRSF000524 1 355 2.8E-80 T 31-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 DFR86_09460 fa364b579a0a9e0ddf5c18cd1c960d61 371 Pfam PF00266 Aminotransferase class-V 18 326 1.5E-30 T 31-10-2018 IPR000192 Aminotransferase class V domain DFR86_09460 fa364b579a0a9e0ddf5c18cd1c960d61 371 Gene3D G3DSA:3.90.1150.10 2 345 1.1E-91 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_09285 d832599e7f467525d2f9865d533442cb 130 SUPERFAMILY SSF56276 16 127 1.88E-34 T 31-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 DFR86_09285 d832599e7f467525d2f9865d533442cb 130 Hamap MF_01298 Arginine decarboxylase proenzyme. 7 129 48.245 T 31-10-2018 IPR027549 Arginine decarboxylase proenzyme GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 DFR86_09285 d832599e7f467525d2f9865d533442cb 130 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 14 130 26.56 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR86_09285 d832599e7f467525d2f9865d533442cb 130 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 15 128 3.2E-40 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR86_09285 d832599e7f467525d2f9865d533442cb 130 Gene3D G3DSA:3.60.90.10 5 130 3.6E-37 T 31-10-2018 DFR86_09285 d832599e7f467525d2f9865d533442cb 130 Pfam PF02675 S-adenosylmethionine decarboxylase 20 127 6.8E-34 T 31-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR86_08020 f542a203a20d4ae2d4f943df320da46f 404 Gene3D G3DSA:3.40.1190.20 1 274 6.6E-87 T 31-10-2018 IPR029056 Ribokinase-like DFR86_08020 f542a203a20d4ae2d4f943df320da46f 404 SUPERFAMILY SSF53613 5 259 2.96E-68 T 31-10-2018 IPR029056 Ribokinase-like DFR86_08020 f542a203a20d4ae2d4f943df320da46f 404 Pfam PF08543 Phosphomethylpyrimidine kinase 14 254 2.2E-82 T 31-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 DFR86_08020 f542a203a20d4ae2d4f943df320da46f 404 SUPERFAMILY SSF53639 264 402 9.02E-8 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR86_08020 f542a203a20d4ae2d4f943df320da46f 404 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 255 1.0E-93 T 31-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DFR86_01060 bab02b863f32ec54a9e77c6093cf2260 624 Gene3D G3DSA:3.40.50.12780 38 498 1.4E-83 T 31-10-2018 DFR86_01060 bab02b863f32ec54a9e77c6093cf2260 624 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 12 65 2.5E-14 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR86_01060 bab02b863f32ec54a9e77c6093cf2260 624 Pfam PF13193 AMP-binding enzyme C-terminal domain 512 587 5.9E-13 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR86_01060 bab02b863f32ec54a9e77c6093cf2260 624 Pfam PF00501 AMP-binding enzyme 74 504 2.6E-70 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR86_01060 bab02b863f32ec54a9e77c6093cf2260 624 ProSitePatterns PS00455 Putative AMP-binding domain signature. 243 254 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR86_01060 bab02b863f32ec54a9e77c6093cf2260 624 SUPERFAMILY SSF56801 4 618 1.44E-126 T 31-10-2018 DFR86_01060 bab02b863f32ec54a9e77c6093cf2260 624 Gene3D G3DSA:3.30.300.30 499 623 4.3E-22 T 31-10-2018 DFR86_02740 22524f957d242e8d67c1cc84e65929f1 610 Pfam PF12439 Glycogen debranching enzyme N terminal 10 214 1.5E-52 T 31-10-2018 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal DFR86_02740 22524f957d242e8d67c1cc84e65929f1 610 Gene3D G3DSA:1.50.10.10 271 598 9.6E-33 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR86_02740 22524f957d242e8d67c1cc84e65929f1 610 Pfam PF06202 Amylo-alpha-1,6-glucosidase 252 602 6.1E-117 T 31-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 DFR86_02740 22524f957d242e8d67c1cc84e65929f1 610 TIGRFAM TIGR01561 gde_arch: putative glycogen debranching enzyme, archaeal type 11 543 1.0E-192 T 31-10-2018 IPR006451 Glycogen debranching enzyme, archaeal type DFR86_02740 22524f957d242e8d67c1cc84e65929f1 610 SUPERFAMILY SSF48208 182 604 1.32E-75 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR86_09580 1e22ec1574a7ff5fa973096b57191c82 481 Gene3D G3DSA:3.40.1670.10 326 442 1.6E-36 T 31-10-2018 DFR86_09580 1e22ec1574a7ff5fa973096b57191c82 481 SUPERFAMILY SSF50475 3 311 3.92E-89 T 31-10-2018 DFR86_09580 1e22ec1574a7ff5fa973096b57191c82 481 SUPERFAMILY SSF143968 312 472 6.15E-54 T 31-10-2018 DFR86_09580 1e22ec1574a7ff5fa973096b57191c82 481 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 443 1.7E-125 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 DFR86_09580 1e22ec1574a7ff5fa973096b57191c82 481 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 417 3.6E-128 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 DFR86_10690 7a38367b0b50275a1309ed8e7fc7c80b 462 Pfam PF01523 Putative modulator of DNA gyrase 20 311 1.5E-40 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 DFR86_10690 7a38367b0b50275a1309ed8e7fc7c80b 462 PIRSF PIRSF004919 1 462 1.6E-133 T 31-10-2018 IPR025502 TldD DFR86_10690 7a38367b0b50275a1309ed8e7fc7c80b 462 SUPERFAMILY SSF111283 5 459 3.92E-79 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 DFR86_00760 7102396e4fce5be31877eff18ab08929 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 257 2.4E-16 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_00760 7102396e4fce5be31877eff18ab08929 268 Gene3D G3DSA:1.10.3720.10 1 255 4.4E-41 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_00760 7102396e4fce5be31877eff18ab08929 268 SUPERFAMILY SSF161098 5 267 1.21E-51 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_07715 0043ed349d66d9bac5dfaa8aa6ec0dd3 115 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 17 89 1.6E-14 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR86_07715 0043ed349d66d9bac5dfaa8aa6ec0dd3 115 Gene3D G3DSA:1.10.10.10 7 111 3.1E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_07715 0043ed349d66d9bac5dfaa8aa6ec0dd3 115 SUPERFAMILY SSF46785 13 108 3.31E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_01920 4d38523d8ace165de944cd092c13f183 468 Gene3D G3DSA:3.80.30.20 123 282 1.8E-14 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe DFR86_01920 4d38523d8ace165de944cd092c13f183 468 Pfam PF04055 Radical SAM superfamily 19 219 1.3E-21 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_01920 4d38523d8ace165de944cd092c13f183 468 PIRSF PIRSF005669 1 468 1.5E-219 T 31-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 DFR86_01920 4d38523d8ace165de944cd092c13f183 468 Pfam PF16199 Radical_SAM C-terminal domain 235 315 2.4E-25 T 31-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 DFR86_01920 4d38523d8ace165de944cd092c13f183 468 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 3 466 2.1E-207 T 31-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 DFR86_01920 4d38523d8ace165de944cd092c13f183 468 Pfam PF00583 Acetyltransferase (GNAT) family 356 456 1.4E-8 T 31-10-2018 IPR000182 GNAT domain DFR86_01920 4d38523d8ace165de944cd092c13f183 468 Gene3D G3DSA:3.40.630.30 308 467 2.5E-7 T 31-10-2018 DFR86_01920 4d38523d8ace165de944cd092c13f183 468 SUPERFAMILY SSF102114 14 281 3.27E-31 T 31-10-2018 DFR86_01920 4d38523d8ace165de944cd092c13f183 468 SUPERFAMILY SSF55729 359 463 8.58E-9 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR86_01920 4d38523d8ace165de944cd092c13f183 468 SMART SM00729 14 274 2.9E-42 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_03095 b48dc023e0a8532ad7a3da92538a6e79 181 Gene3D G3DSA:3.40.50.10240 13 97 1.2E-6 T 31-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 DFR86_03095 b48dc023e0a8532ad7a3da92538a6e79 181 SUPERFAMILY SSF63999 14 97 6.15E-11 T 31-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 DFR86_03095 b48dc023e0a8532ad7a3da92538a6e79 181 Pfam PF01973 Protein of unknown function DUF115 10 143 2.0E-24 T 31-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like DFR86_00395 faf6237481e8e53543bbda94fd7cdc54 691 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 364 385 - T 31-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 DFR86_00395 faf6237481e8e53543bbda94fd7cdc54 691 Gene3D G3DSA:1.10.510.10 351 686 7.3E-31 T 31-10-2018 DFR86_00395 faf6237481e8e53543bbda94fd7cdc54 691 Pfam PF06157 Protein of unknown function (DUF973) 23 320 2.0E-24 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR86_00395 faf6237481e8e53543bbda94fd7cdc54 691 Pfam PF00069 Protein kinase domain 358 678 2.4E-25 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR86_00395 faf6237481e8e53543bbda94fd7cdc54 691 SUPERFAMILY SSF56112 350 680 3.69E-36 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR86_00395 faf6237481e8e53543bbda94fd7cdc54 691 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 507 519 - T 31-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DFR86_00395 faf6237481e8e53543bbda94fd7cdc54 691 SMART SM00220 358 686 9.9E-15 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR86_10040 54fe9323ddcdbd3c06b8ea066daec4c2 147 Pfam PF06146 Phosphate-starvation-inducible E 60 125 5.7E-9 T 31-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like DFR86_02190 37f0236bbb728d8d1cea48e9f95010ef 191 Gene3D G3DSA:3.40.50.10630 16 180 9.9E-31 T 31-10-2018 DFR86_02190 37f0236bbb728d8d1cea48e9f95010ef 191 SUPERFAMILY SSF52141 27 174 6.8E-35 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR86_02215 71b341ff8818528b9d2833bc32b08f3d 211 Pfam PF03070 TENA/THI-4/PQQC family 14 204 3.1E-30 T 31-10-2018 IPR004305 Thiaminase-2/PQQC DFR86_02215 71b341ff8818528b9d2833bc32b08f3d 211 SUPERFAMILY SSF48613 1 202 8.46E-46 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR86_02215 71b341ff8818528b9d2833bc32b08f3d 211 Gene3D G3DSA:1.20.910.10 1 207 8.2E-51 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR86_00650 38933ef5dbd47ebb63507a4b3b891038 226 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 127 215 2.5E-19 T 31-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 DFR86_00650 38933ef5dbd47ebb63507a4b3b891038 226 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 7 90 6.2E-20 T 31-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 DFR86_07075 5891a90486e8031af56ffe574eeebb37 177 Gene3D G3DSA:2.70.40.10 1 173 8.9E-48 T 31-10-2018 IPR036157 dUTPase-like superfamily DFR86_07075 5891a90486e8031af56ffe574eeebb37 177 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 168 1.2E-55 T 31-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 DFR86_07075 5891a90486e8031af56ffe574eeebb37 177 Hamap MF_00146 dCTP deaminase [dcd]. 1 169 31.351 T 31-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 DFR86_07075 5891a90486e8031af56ffe574eeebb37 177 SUPERFAMILY SSF51283 1 169 1.22E-45 T 31-10-2018 IPR036157 dUTPase-like superfamily DFR86_07075 5891a90486e8031af56ffe574eeebb37 177 Pfam PF00692 dUTPase 62 164 3.4E-23 T 31-10-2018 IPR029054 dUTPase-like DFR86_03700 8411d44a41225c28ffcd6c9ce372c1b2 141 Pfam PF07843 Protein of unknown function (DUF1634) 36 132 9.5E-18 T 31-10-2018 IPR012861 Protein of unknown function DUF1634 DFR86_09590 3bee2a7a836419f75b9400edcf0b5cd8 445 Gene3D G3DSA:3.40.1160.10 1 289 3.6E-73 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR86_09590 3bee2a7a836419f75b9400edcf0b5cd8 445 PIRSF PIRSF000726 1 443 1.2E-68 T 31-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 DFR86_09590 3bee2a7a836419f75b9400edcf0b5cd8 445 SUPERFAMILY SSF55021 297 387 6.01E-14 T 31-10-2018 DFR86_09590 3bee2a7a836419f75b9400edcf0b5cd8 445 Gene3D G3DSA:3.30.2130.10 294 442 4.9E-17 T 31-10-2018 DFR86_09590 3bee2a7a836419f75b9400edcf0b5cd8 445 Pfam PF00696 Amino acid kinase family 2 277 8.1E-43 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 DFR86_09590 3bee2a7a836419f75b9400edcf0b5cd8 445 SUPERFAMILY SSF53633 1 281 1.01E-56 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR86_09590 3bee2a7a836419f75b9400edcf0b5cd8 445 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 2 440 2.1E-83 T 31-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 DFR86_08560 e267145c98424660936843ed68f4a56c 288 Gene3D G3DSA:3.50.50.60 2 279 6.1E-12 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_00430 5522f6701b801eaed7573c64cfb65621 638 Pfam PF01935 Domain of unknown function DUF87 173 484 2.2E-14 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR86_00430 5522f6701b801eaed7573c64cfb65621 638 SUPERFAMILY SSF52540 142 622 2.27E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00430 5522f6701b801eaed7573c64cfb65621 638 Gene3D G3DSA:3.40.50.300 425 637 2.2E-17 T 31-10-2018 DFR86_00430 5522f6701b801eaed7573c64cfb65621 638 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 496 587 9.7E-6 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_00430 5522f6701b801eaed7573c64cfb65621 638 Gene3D G3DSA:3.40.50.300 155 291 3.7E-15 T 31-10-2018 DFR86_01760 7cd3888acfdca18828929e23684a8b52 206 Pfam PF04493 Endonuclease V 19 185 3.5E-35 T 31-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 DFR86_01760 7cd3888acfdca18828929e23684a8b52 206 Gene3D G3DSA:3.30.2170.10 5 205 1.5E-40 T 31-10-2018 DFR86_09530 8ea26659410d2e503e3af208bb7e2005 199 Gene3D G3DSA:3.20.20.70 3 198 8.1E-29 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_09530 8ea26659410d2e503e3af208bb7e2005 199 SUPERFAMILY SSF51366 4 196 1.88E-29 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR86_09530 8ea26659410d2e503e3af208bb7e2005 199 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 6 193 7.3E-31 T 31-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 DFR86_09530 8ea26659410d2e503e3af208bb7e2005 199 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 198 22.698 T 31-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 DFR86_06040 1d473ea433b6e05e1a40c1a59c3afa13 415 Pfam PF01676 Metalloenzyme superfamily 5 397 1.6E-42 T 31-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 DFR86_06040 1d473ea433b6e05e1a40c1a59c3afa13 415 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 406 43.764 T 31-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_06040 1d473ea433b6e05e1a40c1a59c3afa13 415 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 42 212 5.2E-52 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_06040 1d473ea433b6e05e1a40c1a59c3afa13 415 PIRSF PIRSF006392 1 411 4.9E-150 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_06040 1d473ea433b6e05e1a40c1a59c3afa13 415 SUPERFAMILY SSF53649 5 406 4.71E-36 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 DFR86_06040 1d473ea433b6e05e1a40c1a59c3afa13 415 Gene3D G3DSA:3.30.70.2130 81 234 3.0E-126 T 31-10-2018 DFR86_06040 1d473ea433b6e05e1a40c1a59c3afa13 415 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 404 6.1E-127 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR86_06040 1d473ea433b6e05e1a40c1a59c3afa13 415 Gene3D G3DSA:3.40.720.10 7 400 3.0E-126 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR86_08825 9240f129a39d01fc6c9d63d23cbb4974 99 Pfam PF00355 Rieske [2Fe-2S] domain 7 86 1.5E-10 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR86_08825 9240f129a39d01fc6c9d63d23cbb4974 99 Gene3D G3DSA:2.102.10.10 1 99 2.4E-17 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_08825 9240f129a39d01fc6c9d63d23cbb4974 99 SUPERFAMILY SSF50022 3 97 3.93E-19 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_02105 11fab326900d40f1d41638800c466ee6 652 Pfam PF05691 Raffinose synthase or seed imbibition protein Sip1 351 554 3.1E-27 T 31-10-2018 IPR008811 Glycosyl hydrolases 36 DFR86_02105 11fab326900d40f1d41638800c466ee6 652 Pfam PF05691 Raffinose synthase or seed imbibition protein Sip1 177 278 2.6E-15 T 31-10-2018 IPR008811 Glycosyl hydrolases 36 DFR86_02105 11fab326900d40f1d41638800c466ee6 652 Gene3D G3DSA:3.20.20.70 214 316 3.3E-11 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_02105 11fab326900d40f1d41638800c466ee6 652 SUPERFAMILY SSF51445 228 513 5.97E-41 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR86_01835 72c68d5173d2ec5028166eba4e104beb 241 Pfam PF00005 ABC transporter 5 136 1.3E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_01835 72c68d5173d2ec5028166eba4e104beb 241 SMART SM00382 5 187 7.4E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_01835 72c68d5173d2ec5028166eba4e104beb 241 SUPERFAMILY SSF52540 3 216 1.42E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01835 72c68d5173d2ec5028166eba4e104beb 241 Gene3D G3DSA:3.40.50.300 2 206 4.8E-52 T 31-10-2018 DFR86_01835 72c68d5173d2ec5028166eba4e104beb 241 ProSitePatterns PS00211 ABC transporters family signature. 108 122 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_03235 79d5ec36933c045ebc3e300da8509d3a 107 Pfam PF01176 Translation initiation factor 1A / IF-1 20 82 4.6E-26 T 31-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 DFR86_03235 79d5ec36933c045ebc3e300da8509d3a 107 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 29 51 - T 31-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 DFR86_03235 79d5ec36933c045ebc3e300da8509d3a 107 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 5 98 27.089 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 DFR86_03235 79d5ec36933c045ebc3e300da8509d3a 107 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 41 93 6.0E-16 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 DFR86_03235 79d5ec36933c045ebc3e300da8509d3a 107 Gene3D G3DSA:2.40.50.140 2 105 2.9E-35 T 31-10-2018 DFR86_03235 79d5ec36933c045ebc3e300da8509d3a 107 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 8 92 7.0E-33 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 DFR86_03235 79d5ec36933c045ebc3e300da8509d3a 107 SUPERFAMILY SSF50249 4 98 5.14E-33 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_03235 79d5ec36933c045ebc3e300da8509d3a 107 SMART SM00652 16 98 1.2E-40 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 SUPERFAMILY SSF56726 75 384 1.7E-86 T 31-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 Gene3D G3DSA:1.10.10.10 1 155 2.2E-58 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 10 385 38.585 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 Pfam PF04406 Type IIB DNA topoisomerase 76 152 2.1E-20 T 31-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 100 111 2.4E-37 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 202 219 2.4E-37 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 147 162 2.4E-37 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 129 146 2.4E-37 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 226 247 2.4E-37 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 258 274 2.4E-37 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 Gene3D G3DSA:3.40.1360.10 156 386 1.4E-84 T 31-10-2018 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 176 194 9.2E-46 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 356 379 9.2E-46 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 42 62 9.2E-46 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 123 140 9.2E-46 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR86_09875 91e01be616a3c4058cbe4d17c61730c8 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 232 252 9.2E-46 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR86_09990 8233ff0201bb24349a6df81c4b36d5f4 353 Gene3D G3DSA:3.90.550.10 1 196 1.2E-23 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_09990 8233ff0201bb24349a6df81c4b36d5f4 353 Gene3D G3DSA:2.160.10.10 197 352 7.1E-31 T 31-10-2018 DFR86_09990 8233ff0201bb24349a6df81c4b36d5f4 353 Pfam PF00483 Nucleotidyl transferase 2 144 1.6E-11 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR86_09990 8233ff0201bb24349a6df81c4b36d5f4 353 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 232 265 9.6E-6 T 31-10-2018 IPR001451 Hexapeptide repeat DFR86_09990 8233ff0201bb24349a6df81c4b36d5f4 353 SUPERFAMILY SSF53448 1 290 1.36E-35 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_09990 8233ff0201bb24349a6df81c4b36d5f4 353 SUPERFAMILY SSF51161 213 350 6.52E-18 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily DFR86_10425 ff0aaa60f22c0f47c98b67b23e27bed8 381 SUPERFAMILY SSF103473 12 372 4.19E-22 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_10425 ff0aaa60f22c0f47c98b67b23e27bed8 381 Pfam PF07690 Major Facilitator Superfamily 195 373 1.4E-12 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_10425 ff0aaa60f22c0f47c98b67b23e27bed8 381 Gene3D G3DSA:1.20.1250.20 188 375 6.5E-15 T 31-10-2018 DFR86_10425 ff0aaa60f22c0f47c98b67b23e27bed8 381 Gene3D G3DSA:1.20.1250.20 6 179 8.1E-7 T 31-10-2018 DFR86_00100 2f1e73d436829a851d5259e83f3dbc5b 173 Gene3D G3DSA:3.40.50.1010 9 147 1.4E-8 T 31-10-2018 DFR86_00100 2f1e73d436829a851d5259e83f3dbc5b 173 SUPERFAMILY SSF88723 9 161 1.6E-9 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR86_00140 5fbff4a7a629cb360a2c9e681dfe2cf4 204 Gene3D G3DSA:1.10.10.10 112 193 1.9E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_00140 5fbff4a7a629cb360a2c9e681dfe2cf4 204 Pfam PF14947 Winged helix-turn-helix 122 178 2.5E-6 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain DFR86_00140 5fbff4a7a629cb360a2c9e681dfe2cf4 204 SUPERFAMILY SSF46785 122 182 5.29E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_05805 37347eae92bd062066f78ac8946d2b47 419 SUPERFAMILY SSF56042 206 361 4.93E-18 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_05805 37347eae92bd062066f78ac8946d2b47 419 SUPERFAMILY SSF55326 86 200 6.11E-15 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_05805 37347eae92bd062066f78ac8946d2b47 419 Gene3D G3DSA:3.90.650.10 207 371 1.7E-16 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_05805 37347eae92bd062066f78ac8946d2b47 419 Pfam PF00586 AIR synthase related protein, N-terminal domain 93 199 6.1E-5 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR86_05805 37347eae92bd062066f78ac8946d2b47 419 Pfam PF02769 AIR synthase related protein, C-terminal domain 213 351 4.8E-12 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR86_05805 37347eae92bd062066f78ac8946d2b47 419 Gene3D G3DSA:3.30.1330.10 48 202 8.1E-13 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_04555 4306edf724009da36935bec7ca102339 605 Pfam PF12801 4Fe-4S binding domain 246 272 5.9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_04555 4306edf724009da36935bec7ca102339 605 Pfam PF12801 4Fe-4S binding domain 153 203 6.1E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_00435 8a60713b5f0e7abb4b91229afa26ca0c 476 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 154 173 9.6E-5 T 31-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site DFR86_00435 8a60713b5f0e7abb4b91229afa26ca0c 476 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 3 430 5.3E-16 T 31-10-2018 IPR019016 CRISPR-associated DxTHG protein DFR86_00435 8a60713b5f0e7abb4b91229afa26ca0c 476 SUPERFAMILY SSF160980 2 455 1.44E-38 T 31-10-2018 DFR86_00435 8a60713b5f0e7abb4b91229afa26ca0c 476 Gene3D G3DSA:3.40.50.10640 1 286 1.0E-35 T 31-10-2018 DFR86_07215 49d62a168d9607fb72d3f272ae086427 232 SUPERFAMILY SSF54534 3 152 3.93E-38 T 31-10-2018 DFR86_07215 49d62a168d9607fb72d3f272ae086427 232 Gene3D G3DSA:3.10.50.40 5 148 8.5E-50 T 31-10-2018 DFR86_07215 49d62a168d9607fb72d3f272ae086427 232 Gene3D G3DSA:2.40.10.330 90 134 8.5E-50 T 31-10-2018 DFR86_07215 49d62a168d9607fb72d3f272ae086427 232 Gene3D G3DSA:3.30.70.2210 153 231 3.4E-7 T 31-10-2018 DFR86_07215 49d62a168d9607fb72d3f272ae086427 232 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 148 5.8E-14 T 31-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain DFR86_03930 26675eda7e34da70e33edae13d1c8eb4 224 PIRSF PIRSF022145 1 224 1.7E-79 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR86_03930 26675eda7e34da70e33edae13d1c8eb4 224 TIGRFAM TIGR03094 sulfo_cyanin: sulfocyanin 60 223 1.7E-52 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR86_03930 26675eda7e34da70e33edae13d1c8eb4 224 Gene3D G3DSA:2.60.40.420 39 213 4.0E-22 T 31-10-2018 IPR008972 Cupredoxin DFR86_03930 26675eda7e34da70e33edae13d1c8eb4 224 ProSitePatterns PS00079 Multicopper oxidases signature 1. 191 211 - T 31-10-2018 IPR033138 Multicopper oxidases, conserved site DFR86_03930 26675eda7e34da70e33edae13d1c8eb4 224 Pfam PF06525 Sulfocyanin (SoxE) domain 78 223 1.7E-61 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR86_03930 26675eda7e34da70e33edae13d1c8eb4 224 SUPERFAMILY SSF49503 77 212 4.13E-18 T 31-10-2018 IPR008972 Cupredoxin DFR86_07285 496df85f13a9eba5ba24b196f9d3e7f1 264 Gene3D G3DSA:3.40.1160.10 1 264 8.0E-53 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR86_07285 496df85f13a9eba5ba24b196f9d3e7f1 264 Hamap MF_02082 [LysW]-aminoadipate/[LysW]-glutamate kinase [lysZ]. 1 262 48.11 T 31-10-2018 IPR037529 [LysW]-aminoadipate/[LysW]-glutamate kinase GO:0016301 DFR86_07285 496df85f13a9eba5ba24b196f9d3e7f1 264 TIGRFAM TIGR00761 argB: acetylglutamate kinase 1 241 8.1E-53 T 31-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR86_07285 496df85f13a9eba5ba24b196f9d3e7f1 264 SUPERFAMILY SSF53633 1 263 1.01E-48 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR86_07285 496df85f13a9eba5ba24b196f9d3e7f1 264 PIRSF PIRSF000728 1 264 3.8E-67 T 31-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR86_07285 496df85f13a9eba5ba24b196f9d3e7f1 264 Pfam PF00696 Amino acid kinase family 1 243 4.8E-31 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 DFR86_00010 d9b320dfc39feae4f078f8aee70772c7 259 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 40 255 8.4E-38 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 DFR86_00010 d9b320dfc39feae4f078f8aee70772c7 259 Gene3D G3DSA:3.30.70.1900 117 259 6.0E-41 T 31-10-2018 DFR86_00010 d9b320dfc39feae4f078f8aee70772c7 259 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 130 253 8.2E-18 T 31-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal DFR86_00010 d9b320dfc39feae4f078f8aee70772c7 259 Gene3D G3DSA:3.30.70.2990 1 116 6.6E-13 T 31-10-2018 DFR86_11740 d9b320dfc39feae4f078f8aee70772c7 259 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 40 255 8.4E-38 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 DFR86_11740 d9b320dfc39feae4f078f8aee70772c7 259 Gene3D G3DSA:3.30.70.1900 117 259 6.0E-41 T 31-10-2018 DFR86_11740 d9b320dfc39feae4f078f8aee70772c7 259 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 130 253 8.2E-18 T 31-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal DFR86_11740 d9b320dfc39feae4f078f8aee70772c7 259 Gene3D G3DSA:3.30.70.2990 1 116 6.6E-13 T 31-10-2018 DFR86_05885 d724212c8d595c200ab8f8c2db470659 300 SUPERFAMILY SSF50447 137 217 8.84E-13 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR86_05885 d724212c8d595c200ab8f8c2db470659 300 Gene3D G3DSA:2.40.30.10 137 216 1.1E-12 T 31-10-2018 DFR86_08490 727e50fea6247ebeed7cf659eac45f15 196 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 193 29.303 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 DFR86_08490 727e50fea6247ebeed7cf659eac45f15 196 Gene3D G3DSA:3.40.50.880 1 195 1.1E-51 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_08490 727e50fea6247ebeed7cf659eac45f15 196 SUPERFAMILY SSF52317 3 183 6.36E-39 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_08490 727e50fea6247ebeed7cf659eac45f15 196 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 192 1.3E-61 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 DFR86_08490 727e50fea6247ebeed7cf659eac45f15 196 PIRSF PIRSF000495 1 196 2.0E-55 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 DFR86_08490 727e50fea6247ebeed7cf659eac45f15 196 Pfam PF00117 Glutamine amidotransferase class-I 7 185 5.6E-20 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR86_09260 9d33d870571db15c0b38829bb191e873 331 Gene3D G3DSA:3.90.105.20 107 186 1.9E-57 T 31-10-2018 DFR86_09260 9d33d870571db15c0b38829bb191e873 331 SUPERFAMILY SSF160369 8 138 4.18E-26 T 31-10-2018 DFR86_09260 9d33d870571db15c0b38829bb191e873 331 Pfam PF00466 Ribosomal protein L10 9 105 1.8E-25 T 31-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 DFR86_09260 9d33d870571db15c0b38829bb191e873 331 Gene3D G3DSA:3.30.70.1730 20 208 1.9E-57 T 31-10-2018 DFR86_09260 9d33d870571db15c0b38829bb191e873 331 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 6 283 32.786 T 31-10-2018 IPR022909 50S ribosomal protein L10, archaea DFR86_03350 374e3c7690f0a7b7f71e1ea150da2594 179 Gene3D G3DSA:3.60.21.10 1 176 1.2E-10 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR86_03350 374e3c7690f0a7b7f71e1ea150da2594 179 SUPERFAMILY SSF56300 1 158 3.64E-14 T 31-10-2018 DFR86_04030 59eb51150903eeff0896421daacfcf55 272 SUPERFAMILY SSF103501 159 257 1.31E-7 T 31-10-2018 IPR036197 NarG-like superfamily DFR86_02510 8c64ae041d402279cb108321f9f2e4d9 307 Gene3D G3DSA:3.90.245.10 4 305 3.8E-108 T 31-10-2018 IPR036452 Ribonucleoside hydrolase-like DFR86_02510 8c64ae041d402279cb108321f9f2e4d9 307 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 6 297 2.3E-74 T 31-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DFR86_02510 8c64ae041d402279cb108321f9f2e4d9 307 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 9 19 - T 31-10-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 DFR86_02510 8c64ae041d402279cb108321f9f2e4d9 307 SUPERFAMILY SSF53590 4 304 3.27E-84 T 31-10-2018 IPR036452 Ribonucleoside hydrolase-like DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 2 130 33.777 T 31-10-2018 IPR022847 Translation elongation factor IF5A, archaeal DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 Gene3D G3DSA:2.30.30.30 1 68 1.7E-28 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 Gene3D G3DSA:2.40.50.140 69 131 3.2E-27 T 31-10-2018 DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 131 6.1E-7 T 31-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 8 39 4.8E-7 T 31-10-2018 IPR013185 Translation elongation factor, KOW-like DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 PIRSF PIRSF003025 1 131 1.6E-47 T 31-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 SUPERFAMILY SSF50249 69 130 9.42E-14 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 6 131 1.9E-42 T 31-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 SUPERFAMILY SSF50104 2 77 1.86E-21 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 SMART SM01376 69 131 3.5E-20 T 31-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 DFR86_09880 32bd597380a3a77b8bd3669d38f4225a 131 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 34 41 - T 31-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 DFR86_02885 e6abe796708e124216445468fb323d91 216 SUPERFAMILY SSF53850 69 192 1.16E-8 T 31-10-2018 DFR86_02885 e6abe796708e124216445468fb323d91 216 Gene3D G3DSA:3.40.190.200 2 213 4.8E-50 T 31-10-2018 DFR86_02885 e6abe796708e124216445468fb323d91 216 Pfam PF12916 Protein of unknown function (DUF3834) 1 197 6.2E-81 T 31-10-2018 IPR024533 Protein of unknown function DUF3834 DFR86_05860 b8548598cde4da8618c233b32555bcb7 357 SMART SM00228 187 259 2.2E-4 T 31-10-2018 IPR001478 PDZ domain GO:0005515 DFR86_05860 b8548598cde4da8618c233b32555bcb7 357 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 203 242 1.4E-6 T 31-10-2018 IPR001478 PDZ domain GO:0005515 DFR86_05860 b8548598cde4da8618c233b32555bcb7 357 Pfam PF02163 Peptidase family M50 114 344 3.3E-22 T 31-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 DFR86_05860 b8548598cde4da8618c233b32555bcb7 357 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 123 137 3.2E-18 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 DFR86_05860 b8548598cde4da8618c233b32555bcb7 357 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 139 154 3.2E-18 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 DFR86_05860 b8548598cde4da8618c233b32555bcb7 357 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 100 119 3.2E-18 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 DFR86_05860 b8548598cde4da8618c233b32555bcb7 357 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 155 167 3.2E-18 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 DFR86_05860 b8548598cde4da8618c233b32555bcb7 357 Gene3D G3DSA:2.30.42.10 194 265 1.3E-9 T 31-10-2018 DFR86_05860 b8548598cde4da8618c233b32555bcb7 357 SUPERFAMILY SSF50156 202 284 3.94E-12 T 31-10-2018 IPR036034 PDZ superfamily GO:0005515 DFR86_10520 d439eb9058ee1a427541d5bd099370d9 233 SUPERFAMILY SSF56235 33 225 6.56E-11 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_10520 d439eb9058ee1a427541d5bd099370d9 233 Gene3D G3DSA:3.60.20.10 1 204 1.0E-12 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_04285 920b04829459207c9bde71947a8a18f7 615 Gene3D G3DSA:1.20.1740.10 14 486 6.7E-59 T 31-10-2018 DFR86_04285 920b04829459207c9bde71947a8a18f7 615 Pfam PF13520 Amino acid permease 25 453 6.1E-42 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04285 920b04829459207c9bde71947a8a18f7 615 PIRSF PIRSF006060 467 609 360.0 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04285 920b04829459207c9bde71947a8a18f7 615 PIRSF PIRSF006060 2 485 3.2E-69 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_10580 a59f6a7c73b2da3686d6737fe0856d5f 314 SUPERFAMILY SSF53474 19 294 6.37E-26 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_10580 a59f6a7c73b2da3686d6737fe0856d5f 314 Gene3D G3DSA:3.40.50.1820 20 303 2.2E-32 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_10580 a59f6a7c73b2da3686d6737fe0856d5f 314 Pfam PF00756 Putative esterase 90 293 9.3E-15 T 31-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 DFR86_10485 6c81e2ac2da8617e4ca8534ebadcfc68 324 Gene3D G3DSA:3.50.50.100 1 322 3.4E-62 T 31-10-2018 DFR86_10485 6c81e2ac2da8617e4ca8534ebadcfc68 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 226 248 2.2E-8 T 31-10-2018 DFR86_10485 6c81e2ac2da8617e4ca8534ebadcfc68 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.2E-8 T 31-10-2018 DFR86_10485 6c81e2ac2da8617e4ca8534ebadcfc68 324 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 118 136 2.2E-8 T 31-10-2018 DFR86_10485 6c81e2ac2da8617e4ca8534ebadcfc68 324 SUPERFAMILY SSF51905 2 274 2.96E-26 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_10485 6c81e2ac2da8617e4ca8534ebadcfc68 324 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 265 3.2E-39 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_10110 78a619be7dd54b337d78bff048224525 151 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 147 34.299 T 31-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 DFR86_10110 78a619be7dd54b337d78bff048224525 151 SUPERFAMILY SSF46767 70 148 7.19E-24 T 31-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 DFR86_10110 78a619be7dd54b337d78bff048224525 151 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 71 146 5.2E-24 T 31-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 DFR86_10110 78a619be7dd54b337d78bff048224525 151 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 118 124 - T 31-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 DFR86_10110 78a619be7dd54b337d78bff048224525 151 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 71 148 1.2E-23 T 31-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 DFR86_10110 78a619be7dd54b337d78bff048224525 151 Gene3D G3DSA:1.10.10.10 68 151 2.8E-29 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10110 78a619be7dd54b337d78bff048224525 151 Gene3D G3DSA:3.30.160.70 1 67 5.8E-40 T 31-10-2018 DFR86_05740 dbc934cc5c42ca34cffd3715255d2bc9 365 Pfam PF01070 FMN-dependent dehydrogenase 175 338 5.4E-15 T 31-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 DFR86_05740 dbc934cc5c42ca34cffd3715255d2bc9 365 Gene3D G3DSA:3.20.20.70 1 365 9.7E-128 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_05740 dbc934cc5c42ca34cffd3715255d2bc9 365 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 2 342 40.355 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 DFR86_05740 dbc934cc5c42ca34cffd3715255d2bc9 365 SUPERFAMILY SSF51395 25 359 1.31E-75 T 31-10-2018 DFR86_05740 dbc934cc5c42ca34cffd3715255d2bc9 365 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 340 2.7E-125 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 DFR86_05740 dbc934cc5c42ca34cffd3715255d2bc9 365 SMART SM01240 24 350 0.0065 T 31-10-2018 DFR86_05740 dbc934cc5c42ca34cffd3715255d2bc9 365 PIRSF PIRSF003314 1 352 1.2E-127 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 Gene3D G3DSA:3.30.1330.30 1 125 1.8E-44 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 31-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 121 2.6E-55 T 31-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 32.85 T 31-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 2.2E-29 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 2.2E-29 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 2.2E-29 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 2.2E-29 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 2.2E-29 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 SUPERFAMILY SSF55315 4 120 2.5E-40 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 19 109 2.8E-32 T 31-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 8.3E-21 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 8.3E-21 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 8.3E-21 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family DFR86_05715 ac5c5ebc05c119b66d1233106d036dc9 125 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 8.3E-21 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family DFR86_05600 00d6b93a1c110e6129e24f36908b9431 227 SMART SM00525 200 220 1.8E-4 T 31-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 DFR86_05600 00d6b93a1c110e6129e24f36908b9431 227 SUPERFAMILY SSF48150 10 222 1.51E-64 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 DFR86_05600 00d6b93a1c110e6129e24f36908b9431 227 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 201 217 - T 31-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 DFR86_05600 00d6b93a1c110e6129e24f36908b9431 227 Pfam PF00633 Helix-hairpin-helix motif 123 141 1.7E-6 T 31-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 DFR86_05600 00d6b93a1c110e6129e24f36908b9431 227 SMART SM00478 44 199 8.6E-44 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 DFR86_05600 00d6b93a1c110e6129e24f36908b9431 227 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 40 182 5.6E-20 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 DFR86_05600 00d6b93a1c110e6129e24f36908b9431 227 SMART SM00278 124 143 0.0046 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 DFR86_05600 00d6b93a1c110e6129e24f36908b9431 227 Gene3D G3DSA:1.10.340.30 27 147 6.5E-62 T 31-10-2018 DFR86_05600 00d6b93a1c110e6129e24f36908b9431 227 PIRSF PIRSF001435 5 225 1.8E-64 T 31-10-2018 DFR86_05600 00d6b93a1c110e6129e24f36908b9431 227 Gene3D G3DSA:1.10.1670.10 23 217 6.5E-62 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 DFR86_10295 d13c93166387a56a35850627acffc344 413 Gene3D G3DSA:1.20.1250.20 215 398 2.1E-10 T 31-10-2018 DFR86_10295 d13c93166387a56a35850627acffc344 413 Gene3D G3DSA:1.20.1250.20 12 207 1.6E-16 T 31-10-2018 DFR86_10295 d13c93166387a56a35850627acffc344 413 Pfam PF07690 Major Facilitator Superfamily 23 207 8.9E-13 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_10295 d13c93166387a56a35850627acffc344 413 Pfam PF07690 Major Facilitator Superfamily 219 400 7.1E-13 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_10295 d13c93166387a56a35850627acffc344 413 SUPERFAMILY SSF103473 17 400 1.96E-39 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_05670 8ce59362b95b26bab0459e6ebb2d78e0 468 Pfam PF01409 tRNA synthetases class II core domain (F) 202 463 7.5E-81 T 31-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 DFR86_05670 8ce59362b95b26bab0459e6ebb2d78e0 468 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 1 465 37.075 T 31-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 DFR86_05670 8ce59362b95b26bab0459e6ebb2d78e0 468 SUPERFAMILY SSF55681 202 464 2.39E-62 T 31-10-2018 DFR86_05670 8ce59362b95b26bab0459e6ebb2d78e0 468 Gene3D G3DSA:1.10.10.2310 20 199 6.4E-20 T 31-10-2018 DFR86_05670 8ce59362b95b26bab0459e6ebb2d78e0 468 Gene3D G3DSA:1.10.10.2330 71 125 6.4E-20 T 31-10-2018 DFR86_05670 8ce59362b95b26bab0459e6ebb2d78e0 468 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 160 465 5.4E-95 T 31-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 DFR86_05670 8ce59362b95b26bab0459e6ebb2d78e0 468 Gene3D G3DSA:3.30.930.10 217 467 2.7E-78 T 31-10-2018 DFR86_05670 8ce59362b95b26bab0459e6ebb2d78e0 468 Gene3D G3DSA:1.10.10.2320 58 159 6.4E-20 T 31-10-2018 DFR86_08070 b2d284e16df9ff69bab9d5a77c9b0485 229 SUPERFAMILY SSF53448 1 226 9.21E-43 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_08070 b2d284e16df9ff69bab9d5a77c9b0485 229 Gene3D G3DSA:3.90.550.10 1 228 4.6E-42 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_08070 b2d284e16df9ff69bab9d5a77c9b0485 229 Pfam PF00535 Glycosyl transferase family 2 5 168 7.3E-29 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_05910 ebe046031fb099a894a2066d1c888381 294 PRINTS PR00116 Arginase signature 255 284 5.7E-5 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 DFR86_05910 ebe046031fb099a894a2066d1c888381 294 PRINTS PR00116 Arginase signature 110 125 5.7E-5 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 DFR86_05910 ebe046031fb099a894a2066d1c888381 294 Pfam PF00491 Arginase family 27 284 1.2E-71 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 DFR86_05910 ebe046031fb099a894a2066d1c888381 294 SUPERFAMILY SSF52768 26 286 7.74E-79 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily DFR86_05910 ebe046031fb099a894a2066d1c888381 294 PIRSF PIRSF036979 5 293 5.2E-91 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 DFR86_05910 ebe046031fb099a894a2066d1c888381 294 Gene3D G3DSA:3.40.800.10 8 292 9.4E-80 T 31-10-2018 DFR86_05910 ebe046031fb099a894a2066d1c888381 294 TIGRFAM TIGR01230 agmatinase: agmatinase 26 285 1.1E-70 T 31-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 DFR86_09935 c62e45db21ff46bdf51f8dd70e2bd1cc 340 TIGRFAM TIGR03961 rSAM_PTO1314: archaeal radical SAM protein, PTO1314 family 4 337 2.8E-166 T 31-10-2018 IPR023863 Archaeal radical SAM protein, PTO1314 family DFR86_09935 c62e45db21ff46bdf51f8dd70e2bd1cc 340 Pfam PF04055 Radical SAM superfamily 34 163 1.0E-16 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_09935 c62e45db21ff46bdf51f8dd70e2bd1cc 340 Pfam PF11946 Domain of unknown function (DUF3463) 189 326 1.1E-25 T 31-10-2018 IPR022563 Domain of unknown function DUF3463 DFR86_09935 c62e45db21ff46bdf51f8dd70e2bd1cc 340 Gene3D G3DSA:3.20.20.70 31 303 1.3E-44 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_09935 c62e45db21ff46bdf51f8dd70e2bd1cc 340 Pfam PF13353 4Fe-4S single cluster domain 33 130 8.2E-6 T 31-10-2018 DFR86_09935 c62e45db21ff46bdf51f8dd70e2bd1cc 340 SUPERFAMILY SSF102114 31 306 8.04E-48 T 31-10-2018 DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 Pfam PF10415 Fumarase C C-terminus 381 431 7.9E-11 T 31-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 Gene3D G3DSA:1.10.40.30 379 435 1.1E-10 T 31-10-2018 DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 Pfam PF00206 Lyase 2 315 1.2E-90 T 31-10-2018 IPR022761 Fumarate lyase, N-terminal DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 Gene3D G3DSA:1.20.200.10 111 378 9.2E-82 T 31-10-2018 DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 PRINTS PR00149 Fumarate lyase superfamily signature 242 269 2.6E-24 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 2.6E-24 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 PRINTS PR00149 Fumarate lyase superfamily signature 290 306 2.6E-24 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 PRINTS PR00149 Fumarate lyase superfamily signature 152 170 2.6E-24 T 31-10-2018 IPR000362 Fumarate lyase family DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 Gene3D G3DSA:1.10.275.10 2 110 1.5E-35 T 31-10-2018 IPR024083 Fumarase/histidase, N-terminal DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 ProSitePatterns PS00163 Fumarate lyases signature. 290 299 - T 31-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 PRINTS PR00145 Argininosuccinate lyase family signature 105 127 4.7E-6 T 31-10-2018 DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 PRINTS PR00145 Argininosuccinate lyase family signature 290 306 4.7E-6 T 31-10-2018 DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 PRINTS PR00145 Argininosuccinate lyase family signature 147 167 4.7E-6 T 31-10-2018 DFR86_01485 ed6c5643bab3dd65eb4c7e74c7250bd6 439 SUPERFAMILY SSF48557 4 430 3.83E-107 T 31-10-2018 IPR008948 L-Aspartase-like GO:0003824 DFR86_07090 98814b75f1279f0c08c538efb445ade0 368 Pfam PF01266 FAD dependent oxidoreductase 1 338 3.0E-44 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DFR86_07090 98814b75f1279f0c08c538efb445ade0 368 Gene3D G3DSA:3.50.50.60 1 342 1.5E-65 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_07090 98814b75f1279f0c08c538efb445ade0 368 SUPERFAMILY SSF51905 1 357 5.57E-36 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_07090 98814b75f1279f0c08c538efb445ade0 368 Gene3D G3DSA:3.30.9.10 80 297 1.5E-65 T 31-10-2018 DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 SMART SM01074 302 383 1.6E-28 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 Gene3D G3DSA:1.10.8.60 21 286 2.6E-106 T 31-10-2018 DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 Pfam PF13401 AAA domain 56 177 1.7E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 17 372 6.8E-135 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 Gene3D G3DSA:1.10.10.10 294 395 9.0E-30 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 SUPERFAMILY SSF46785 286 385 7.86E-27 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 Pfam PF09079 CDC6, C terminal winged helix domain 302 382 4.0E-21 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 Hamap MF_01407 ORC1-type DNA replication protein. 10 383 32.677 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 SMART SM00382 55 208 5.1E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 Gene3D G3DSA:3.40.50.300 33 206 2.6E-106 T 31-10-2018 DFR86_06410 d53d6c831dc94275cea89b9a5aee8c2e 396 SUPERFAMILY SSF52540 17 279 1.33E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_11665 d2327dc1a530dd896514d58c48bcfc35 637 Pfam PF00270 DEAD/DEAH box helicase 29 105 1.0E-6 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_11665 d2327dc1a530dd896514d58c48bcfc35 637 Gene3D G3DSA:3.40.50.300 274 458 9.4E-8 T 31-10-2018 DFR86_11665 d2327dc1a530dd896514d58c48bcfc35 637 SUPERFAMILY SSF52540 38 399 3.11E-21 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_11665 d2327dc1a530dd896514d58c48bcfc35 637 SMART SM00487 23 284 1.3E-10 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_04610 586ba057adf178fbf0fa1a3e35523a86 550 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 319 3.4E-58 T 31-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 DFR86_04610 586ba057adf178fbf0fa1a3e35523a86 550 SUPERFAMILY SSF51971 321 462 1.88E-16 T 31-10-2018 DFR86_04610 586ba057adf178fbf0fa1a3e35523a86 550 Pfam PF13450 NAD(P)-binding Rossmann-like domain 363 403 7.2E-7 T 31-10-2018 DFR86_04610 586ba057adf178fbf0fa1a3e35523a86 550 SUPERFAMILY SSF51395 3 344 1.03E-93 T 31-10-2018 DFR86_04610 586ba057adf178fbf0fa1a3e35523a86 550 Gene3D G3DSA:3.40.50.720 357 471 6.5E-23 T 31-10-2018 DFR86_04610 586ba057adf178fbf0fa1a3e35523a86 550 Gene3D G3DSA:3.20.20.70 1 356 1.5E-99 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_05270 849de82d6f1a1e45d80096ff73261cc7 138 Pfam PF02310 B12 binding domain 5 115 1.2E-22 T 31-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 DFR86_05270 849de82d6f1a1e45d80096ff73261cc7 138 Gene3D G3DSA:3.40.50.280 1 137 6.5E-59 T 31-10-2018 DFR86_05270 849de82d6f1a1e45d80096ff73261cc7 138 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 3 128 3.1E-52 T 31-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 DFR86_05270 849de82d6f1a1e45d80096ff73261cc7 138 SUPERFAMILY SSF52242 3 127 5.23E-49 T 31-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 DFR86_06670 7fb92aa27582338d2ff7d9a0603853db 148 Pfam PF01877 RNA binding 5 124 3.2E-29 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 DFR86_06670 7fb92aa27582338d2ff7d9a0603853db 148 SUPERFAMILY SSF55282 4 128 2.94E-33 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06670 7fb92aa27582338d2ff7d9a0603853db 148 Gene3D G3DSA:3.30.1440.10 1 148 1.8E-37 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_04115 98246ed23aa716555f2a53fe812e3e7c 330 Pfam PF00149 Calcineurin-like phosphoesterase 18 286 3.4E-7 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR86_04115 98246ed23aa716555f2a53fe812e3e7c 330 SUPERFAMILY SSF56300 18 327 8.11E-65 T 31-10-2018 DFR86_04115 98246ed23aa716555f2a53fe812e3e7c 330 Gene3D G3DSA:3.60.21.10 78 327 5.8E-20 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR86_07460 e7c31df93186c0c9762979c5bb33dd28 247 SMART SM00882 2 217 6.2E-19 T 31-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 DFR86_07460 e7c31df93186c0c9762979c5bb33dd28 247 Pfam PF01144 Coenzyme A transferase 1 198 8.7E-25 T 31-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 DFR86_07460 e7c31df93186c0c9762979c5bb33dd28 247 Gene3D G3DSA:3.30.30.40 111 150 6.2E-53 T 31-10-2018 DFR86_07460 e7c31df93186c0c9762979c5bb33dd28 247 Gene3D G3DSA:3.40.1080.10 1 239 6.2E-53 T 31-10-2018 DFR86_07460 e7c31df93186c0c9762979c5bb33dd28 247 SUPERFAMILY SSF100950 2 241 6.63E-56 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR86_11510 9ccc0608e4dba4a7f45e2fa2d059252d 243 Gene3D G3DSA:1.10.10.10 141 212 3.9E-33 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_11510 9ccc0608e4dba4a7f45e2fa2d059252d 243 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 3 204 5.9E-52 T 31-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 DFR86_11510 9ccc0608e4dba4a7f45e2fa2d059252d 243 SUPERFAMILY SSF46785 139 210 3.69E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_11510 9ccc0608e4dba4a7f45e2fa2d059252d 243 Gene3D G3DSA:3.40.50.11700 1 139 1.5E-62 T 31-10-2018 DFR86_11510 9ccc0608e4dba4a7f45e2fa2d059252d 243 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 146 193 3.6E-6 T 31-10-2018 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain DFR86_00810 af97436163dd441208b199b40f572b20 548 SMART SM00486 15 392 1.1E-16 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_00810 af97436163dd441208b199b40f572b20 548 SUPERFAMILY SSF56672 214 546 5.56E-56 T 31-10-2018 DFR86_00810 af97436163dd441208b199b40f572b20 548 Gene3D G3DSA:3.90.1600.10 250 418 4.3E-44 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_00810 af97436163dd441208b199b40f572b20 548 Gene3D G3DSA:1.10.287.690 301 347 4.3E-44 T 31-10-2018 DFR86_00810 af97436163dd441208b199b40f572b20 548 Pfam PF00136 DNA polymerase family B 245 377 8.9E-11 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR86_08240 cdf44a9f13e7c3055f7aaa7206b811b0 144 Gene3D G3DSA:1.20.58.500 58 141 1.6E-12 T 31-10-2018 DFR86_08240 cdf44a9f13e7c3055f7aaa7206b811b0 144 Pfam PF03745 Domain of unknown function (DUF309) 64 116 1.8E-16 T 31-10-2018 IPR005500 Protein of unknown function DUF309 DFR86_08240 cdf44a9f13e7c3055f7aaa7206b811b0 144 SUPERFAMILY SSF140663 59 135 2.62E-19 T 31-10-2018 IPR023203 TTHA0068-like superfamily DFR86_02045 fe7fd4ee62d8cbea65b7d39180b4db73 398 SUPERFAMILY SSF56059 119 388 7.28E-54 T 31-10-2018 DFR86_02045 fe7fd4ee62d8cbea65b7d39180b4db73 398 Gene3D G3DSA:3.40.50.20 1 123 8.3E-47 T 31-10-2018 DFR86_02045 fe7fd4ee62d8cbea65b7d39180b4db73 398 Gene3D G3DSA:3.30.470.20 196 397 8.2E-54 T 31-10-2018 DFR86_02045 fe7fd4ee62d8cbea65b7d39180b4db73 398 SUPERFAMILY SSF52440 3 111 1.27E-31 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR86_02045 fe7fd4ee62d8cbea65b7d39180b4db73 398 Pfam PF02222 ATP-grasp domain 122 297 5.7E-43 T 31-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type DFR86_02045 fe7fd4ee62d8cbea65b7d39180b4db73 398 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 7 395 46.896 T 31-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 DFR86_02045 fe7fd4ee62d8cbea65b7d39180b4db73 398 Gene3D G3DSA:3.30.1490.20 124 195 1.2E-28 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_09845 d4e328475713815c6f88efc175d80569 88 Pfam PF01918 Alba 7 62 2.6E-11 T 31-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 DFR86_09845 d4e328475713815c6f88efc175d80569 88 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 11 88 1.0E-19 T 31-10-2018 DFR86_09845 d4e328475713815c6f88efc175d80569 88 Gene3D G3DSA:3.30.110.20 1 88 6.0E-29 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 DFR86_09845 d4e328475713815c6f88efc175d80569 88 SUPERFAMILY SSF82704 3 86 7.98E-16 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 DFR86_11040 3c3a1305249de7bbc07baf777ef47de8 400 SUPERFAMILY SSF51004 106 368 1.05E-30 T 31-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily DFR86_11040 3c3a1305249de7bbc07baf777ef47de8 400 Gene3D G3DSA:2.130.10.10 118 387 7.7E-24 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_06815 d7747c3cf26b44626ea2f5c56c27ddc5 113 Pfam PF00366 Ribosomal protein S17 40 107 1.1E-21 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06815 d7747c3cf26b44626ea2f5c56c27ddc5 113 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 37 107 1.0E-21 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06815 d7747c3cf26b44626ea2f5c56c27ddc5 113 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 8 110 2.4E-47 T 31-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06815 d7747c3cf26b44626ea2f5c56c27ddc5 113 SUPERFAMILY SSF50249 34 109 5.14E-21 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_06815 d7747c3cf26b44626ea2f5c56c27ddc5 113 Gene3D G3DSA:2.40.50.1000 1 112 1.1E-35 T 31-10-2018 DFR86_06815 d7747c3cf26b44626ea2f5c56c27ddc5 113 ProSitePatterns PS00056 Ribosomal protein S17 signature. 87 99 - T 31-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06815 d7747c3cf26b44626ea2f5c56c27ddc5 113 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 6 111 32.215 T 31-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06815 d7747c3cf26b44626ea2f5c56c27ddc5 113 PRINTS PR00973 Ribosomal protein S17 family signature 87 97 9.5E-9 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06815 d7747c3cf26b44626ea2f5c56c27ddc5 113 PRINTS PR00973 Ribosomal protein S17 family signature 97 104 9.5E-9 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06815 d7747c3cf26b44626ea2f5c56c27ddc5 113 PRINTS PR00973 Ribosomal protein S17 family signature 54 77 9.5E-9 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_02205 da95d4bf880c8794e3f277707838d85e 646 Gene3D G3DSA:3.40.30.10 1 166 8.4E-61 T 31-10-2018 DFR86_02205 da95d4bf880c8794e3f277707838d85e 646 PIRSF PIRSF006402 1 645 1.7E-160 T 31-10-2018 IPR024705 Spermatogenesis-associated protein 20 DFR86_02205 da95d4bf880c8794e3f277707838d85e 646 SUPERFAMILY SSF52833 5 128 1.62E-30 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_02205 da95d4bf880c8794e3f277707838d85e 646 SUPERFAMILY SSF48208 183 490 6.8E-30 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR86_02205 da95d4bf880c8794e3f277707838d85e 646 Pfam PF03190 Protein of unknown function, DUF255 2 155 7.8E-61 T 31-10-2018 IPR004879 Domain of unknown function DUF255 DFR86_06495 228350123289ae0679f631e2f6daa6ea 450 SUPERFAMILY SSF52540 112 448 1.67E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06495 228350123289ae0679f631e2f6daa6ea 450 Pfam PF01935 Domain of unknown function DUF87 120 323 1.5E-29 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR86_06495 228350123289ae0679f631e2f6daa6ea 450 Gene3D G3DSA:3.40.50.300 275 449 3.9E-34 T 31-10-2018 DFR86_06495 228350123289ae0679f631e2f6daa6ea 450 Gene3D G3DSA:3.40.50.300 108 240 4.4E-20 T 31-10-2018 DFR86_09470 0c2c356a8ade0160de128ddcf45b7c66 202 Gene3D G3DSA:1.10.1670.10 16 202 5.2E-59 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 DFR86_09470 0c2c356a8ade0160de128ddcf45b7c66 202 SUPERFAMILY SSF48150 33 197 6.12E-24 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 DFR86_09470 0c2c356a8ade0160de128ddcf45b7c66 202 PIRSF PIRSF005954 1 202 5.9E-70 T 31-10-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 DFR86_09470 0c2c356a8ade0160de128ddcf45b7c66 202 Gene3D G3DSA:1.10.340.30 28 139 5.2E-59 T 31-10-2018 DFR86_09470 0c2c356a8ade0160de128ddcf45b7c66 202 Hamap MF_00241 Probable N-glycosylase/DNA lyase [ogg]. 1 202 29.876 T 31-10-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 DFR86_09470 0c2c356a8ade0160de128ddcf45b7c66 202 SMART SM00478 42 197 1.0E-7 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 DFR86_09805 c3be1ec5c76876a4aa21f3202e6b8143 105 Pfam PF03091 CutA1 divalent ion tolerance protein 4 102 2.4E-37 T 31-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 DFR86_09805 c3be1ec5c76876a4aa21f3202e6b8143 105 Gene3D G3DSA:3.30.70.120 2 105 3.7E-39 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal DFR86_09805 c3be1ec5c76876a4aa21f3202e6b8143 105 SUPERFAMILY SSF54913 4 104 1.37E-38 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta DFR86_03140 5d42dacc3d02670a5c0f8c8957662493 263 PIRSF PIRSF000388 2 260 2.7E-99 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 DFR86_03140 5d42dacc3d02670a5c0f8c8957662493 263 Pfam PF02548 Ketopantoate hydroxymethyltransferase 6 253 8.8E-101 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 DFR86_03140 5d42dacc3d02670a5c0f8c8957662493 263 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 5 255 3.3E-91 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 DFR86_03140 5d42dacc3d02670a5c0f8c8957662493 263 Gene3D G3DSA:3.20.20.60 3 263 1.7E-98 T 31-10-2018 DFR86_03140 5d42dacc3d02670a5c0f8c8957662493 263 SUPERFAMILY SSF51621 5 256 3.3E-94 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR86_03140 5d42dacc3d02670a5c0f8c8957662493 263 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 258 38.902 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 DFR86_03565 a92b94f23ea3acc6901c6e2de4617c7c 496 Gene3D G3DSA:1.10.390.60 145 375 3.1E-49 T 31-10-2018 DFR86_03565 a92b94f23ea3acc6901c6e2de4617c7c 496 Gene3D G3DSA:2.60.40.3650 6 139 9.2E-16 T 31-10-2018 DFR86_03565 a92b94f23ea3acc6901c6e2de4617c7c 496 Pfam PF05299 M61 glycyl aminopeptidase 213 322 3.7E-32 T 31-10-2018 IPR007963 Peptidase M61, catalytic domain DFR86_03565 a92b94f23ea3acc6901c6e2de4617c7c 496 Gene3D G3DSA:2.30.42.10 385 461 8.1E-7 T 31-10-2018 DFR86_03565 a92b94f23ea3acc6901c6e2de4617c7c 496 SMART SM00228 396 465 0.0068 T 31-10-2018 IPR001478 PDZ domain GO:0005515 DFR86_03565 a92b94f23ea3acc6901c6e2de4617c7c 496 SUPERFAMILY SSF55486 184 266 9.52E-5 T 31-10-2018 DFR86_03565 a92b94f23ea3acc6901c6e2de4617c7c 496 PIRSF PIRSF016493 7 489 6.3E-94 T 31-10-2018 IPR024191 Peptidase M61 DFR86_03565 a92b94f23ea3acc6901c6e2de4617c7c 496 SUPERFAMILY SSF50156 378 465 4.45E-9 T 31-10-2018 IPR036034 PDZ superfamily GO:0005515 DFR86_10020 522ae5c5a4f6d6ab3bc1fae982415946 238 SMART SM00530 27 81 1.8E-10 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR86_10020 522ae5c5a4f6d6ab3bc1fae982415946 238 SUPERFAMILY SSF47413 22 74 3.22E-11 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 DFR86_10020 522ae5c5a4f6d6ab3bc1fae982415946 238 PIRSF PIRSF037724 1 234 1.4E-79 T 31-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted DFR86_10020 522ae5c5a4f6d6ab3bc1fae982415946 238 Gene3D G3DSA:1.10.260.40 20 103 2.4E-10 T 31-10-2018 DFR86_10020 522ae5c5a4f6d6ab3bc1fae982415946 238 Pfam PF01381 Helix-turn-helix 28 73 3.0E-9 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR86_05615 2240436585014bfb7f8d926195d3d13e 873 Gene3D G3DSA:3.40.50.300 10 238 7.6E-48 T 31-10-2018 DFR86_05615 2240436585014bfb7f8d926195d3d13e 873 Pfam PF00271 Helicase conserved C-terminal domain 271 376 9.3E-16 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_05615 2240436585014bfb7f8d926195d3d13e 873 PIRSF PIRSF037307 4 872 1.2E-269 T 31-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 DFR86_05615 2240436585014bfb7f8d926195d3d13e 873 SMART SM00487 29 245 3.2E-33 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_05615 2240436585014bfb7f8d926195d3d13e 873 Pfam PF08494 DEAD/H associated 638 827 4.5E-50 T 31-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 DFR86_05615 2240436585014bfb7f8d926195d3d13e 873 SMART SM00490 290 376 1.7E-13 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_05615 2240436585014bfb7f8d926195d3d13e 873 Pfam PF00270 DEAD/DEAH box helicase 34 215 2.0E-29 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_05615 2240436585014bfb7f8d926195d3d13e 873 Gene3D G3DSA:3.40.50.300 251 416 9.4E-25 T 31-10-2018 DFR86_05615 2240436585014bfb7f8d926195d3d13e 873 SUPERFAMILY SSF52540 44 381 2.0E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04635 f8b90f044a2560815001381cdcbb73d1 311 SUPERFAMILY SSF56059 3 307 3.32E-57 T 31-10-2018 DFR86_04635 f8b90f044a2560815001381cdcbb73d1 311 Gene3D G3DSA:3.30.1490.20 1 175 1.3E-31 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR86_04635 f8b90f044a2560815001381cdcbb73d1 311 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 15 304 1.0E-66 T 31-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 DFR86_04635 f8b90f044a2560815001381cdcbb73d1 311 Gene3D G3DSA:3.30.470.20 177 310 8.1E-33 T 31-10-2018 DFR86_00115 ce1b2be72b2aeb4223ceacb2f757cf7c 167 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 3 84 1.2E-20 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_00115 ce1b2be72b2aeb4223ceacb2f757cf7c 167 Pfam PF07282 Putative transposase DNA-binding domain 57 123 1.5E-22 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_01735 8981b12c4924590d14d80a554f4d509b 115 SUPERFAMILY SSF75169 2 115 1.03E-18 T 31-10-2018 IPR027396 DsrEFH-like DFR86_01735 8981b12c4924590d14d80a554f4d509b 115 Gene3D G3DSA:3.40.1260.10 1 115 1.5E-15 T 31-10-2018 IPR027396 DsrEFH-like DFR86_01735 8981b12c4924590d14d80a554f4d509b 115 Pfam PF02635 DsrE/DsrF-like family 3 115 1.8E-14 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR86_11370 69b11bd9387c89b2ad413e08dc950b34 192 SUPERFAMILY SSF53323 4 170 1.7E-30 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR86_11370 69b11bd9387c89b2ad413e08dc950b34 192 Gene3D G3DSA:3.40.920.10 1 187 2.9E-39 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR86_11370 69b11bd9387c89b2ad413e08dc950b34 192 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 177 1.5E-33 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DFR86_11405 5d2146b051810a671158ca22fe1def0f 269 Pfam PF03787 RAMP superfamily 23 185 1.5E-13 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 PRINTS PR00686 Transcription initiation factor TFIID signature 117 132 1.0E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 PRINTS PR00686 Transcription initiation factor TFIID signature 3 18 1.0E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 PRINTS PR00686 Transcription initiation factor TFIID signature 46 64 1.0E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 PRINTS PR00686 Transcription initiation factor TFIID signature 94 110 1.0E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 PRINTS PR00686 Transcription initiation factor TFIID signature 27 46 1.0E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 PRINTS PR00686 Transcription initiation factor TFIID signature 136 152 1.0E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 SUPERFAMILY SSF55945 2 86 8.64E-29 T 31-10-2018 DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 121 170 - T 31-10-2018 IPR030491 TATA-box binding protein, conserved site DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 Gene3D G3DSA:3.30.310.10 8 89 5.2E-34 T 31-10-2018 IPR012295 TBP domain superfamily DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 Hamap MF_00408 TATA-box-binding protein [tbp]. 1 176 36.645 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 92 172 2.1E-30 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 2 82 4.7E-28 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 Gene3D G3DSA:3.30.310.10 90 179 9.9E-38 T 31-10-2018 IPR012295 TBP domain superfamily DFR86_09765 01e69cd7a37fa3ece255753756db5276 188 SUPERFAMILY SSF55945 87 177 1.37E-31 T 31-10-2018 DFR86_11215 5d52eb67ac92bb361640e6f8fafd3317 297 Gene3D G3DSA:3.40.50.970 89 297 1.7E-71 T 31-10-2018 DFR86_11215 5d52eb67ac92bb361640e6f8fafd3317 297 SUPERFAMILY SSF52518 12 296 4.26E-73 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_11215 5d52eb67ac92bb361640e6f8fafd3317 297 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 65 202 1.2E-17 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR86_01005 417431420b9248a617dfc21c4d545aa7 274 Gene3D G3DSA:3.40.50.300 13 274 9.3E-26 T 31-10-2018 DFR86_01005 417431420b9248a617dfc21c4d545aa7 274 SUPERFAMILY SSF52540 23 226 1.84E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01395 cc032e92a2438831fa8294990be132ce 334 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 7 257 9.1E-96 T 31-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 DFR86_01395 cc032e92a2438831fa8294990be132ce 334 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 5 235 8.7E-57 T 31-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR86_01395 cc032e92a2438831fa8294990be132ce 334 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 213 5.2E-46 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR86_01395 cc032e92a2438831fa8294990be132ce 334 Gene3D G3DSA:3.40.1010.10 2 114 7.8E-33 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR86_01395 cc032e92a2438831fa8294990be132ce 334 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 10 24 - T 31-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR86_01395 cc032e92a2438831fa8294990be132ce 334 Gene3D G3DSA:3.30.950.10 115 236 1.1E-42 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 DFR86_01395 cc032e92a2438831fa8294990be132ce 334 SUPERFAMILY SSF53790 5 241 1.96E-66 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR86_09455 74b2057ac6da05a420699061d1314fb9 95 SUPERFAMILY SSF63562 12 92 4.19E-23 T 31-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_09455 74b2057ac6da05a420699061d1314fb9 95 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 23 37 - T 31-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_09455 74b2057ac6da05a420699061d1314fb9 95 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 20 79 19.601 T 31-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_09455 74b2057ac6da05a420699061d1314fb9 95 Gene3D G3DSA:3.90.940.10 2 92 7.7E-28 T 31-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_09455 74b2057ac6da05a420699061d1314fb9 95 SMART SM01409 16 73 7.5E-5 T 31-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_09455 74b2057ac6da05a420699061d1314fb9 95 PIRSF PIRSF000778 2 95 2.7E-26 T 31-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_09455 74b2057ac6da05a420699061d1314fb9 95 Pfam PF01192 RNA polymerase Rpb6 18 73 4.4E-11 T 31-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_03020 c480cc20908e58682f0ca060b6a75a44 140 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 31-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 DFR86_03020 c480cc20908e58682f0ca060b6a75a44 140 Gene3D G3DSA:3.10.180.10 2 139 9.0E-39 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR86_03020 c480cc20908e58682f0ca060b6a75a44 140 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 6 137 9.0E-43 T 31-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 DFR86_03020 c480cc20908e58682f0ca060b6a75a44 140 SUPERFAMILY SSF54593 3 139 1.07E-32 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR86_03020 c480cc20908e58682f0ca060b6a75a44 140 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 122 1.0E-23 T 31-10-2018 DFR86_08740 27fc332d466c4621390d88ac866d7149 164 Pfam PF14697 4Fe-4S dicluster domain 57 108 1.4E-10 T 31-10-2018 DFR86_08740 27fc332d466c4621390d88ac866d7149 164 Gene3D G3DSA:3.30.70.3270 39 164 2.2E-26 T 31-10-2018 DFR86_08740 27fc332d466c4621390d88ac866d7149 164 SUPERFAMILY SSF54862 39 137 4.94E-24 T 31-10-2018 DFR86_08740 27fc332d466c4621390d88ac866d7149 164 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 22 131 3.2E-37 T 31-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08740 27fc332d466c4621390d88ac866d7149 164 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 94 105 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_06855 8f209d660a871d1a86f86af3d75e94ee 133 Pfam PF01655 Ribosomal protein L32 23 131 2.5E-36 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06855 8f209d660a871d1a86f86af3d75e94ee 133 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 23 131 7.0E-36 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06855 8f209d660a871d1a86f86af3d75e94ee 133 SUPERFAMILY SSF52042 10 132 1.57E-40 T 31-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06855 8f209d660a871d1a86f86af3d75e94ee 133 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 6 132 27.788 T 31-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 DFR86_06855 8f209d660a871d1a86f86af3d75e94ee 133 ProSitePatterns PS00580 Ribosomal protein L32e signature. 25 47 - T 31-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06855 8f209d660a871d1a86f86af3d75e94ee 133 SMART SM01393 22 131 1.4E-55 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_04780 fca8c319fcfc370ade07913c08174c60 269 Gene3D G3DSA:2.40.400.10 2 265 4.2E-64 T 31-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DFR86_04780 fca8c319fcfc370ade07913c08174c60 269 SUPERFAMILY SSF160104 4 256 9.42E-37 T 31-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DFR86_04780 fca8c319fcfc370ade07913c08174c60 269 Pfam PF06314 Acetoacetate decarboxylase (ADC) 7 258 1.6E-52 T 31-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DFR86_11550 5358132fb9a99f433ec2a1963ac1ca41 321 TIGRFAM TIGR02583 DevR_archaea: CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN 2 282 9.0E-105 T 31-10-2018 IPR002764 CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern DFR86_11550 5358132fb9a99f433ec2a1963ac1ca41 321 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 4 258 9.9E-54 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR DFR86_11550 5358132fb9a99f433ec2a1963ac1ca41 321 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 5 273 2.4E-77 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR DFR86_00075 cefed2acb53ec3930875ef1f52332fde 945 Pfam PF06634 Protein of unknown function (DUF1156) 19 71 5.4E-6 T 31-10-2018 IPR009537 Domain of unknown function DUF1156 DFR86_00075 cefed2acb53ec3930875ef1f52332fde 945 Gene3D G3DSA:3.40.50.150 61 131 3.5E-6 T 31-10-2018 DFR86_00075 cefed2acb53ec3930875ef1f52332fde 945 SUPERFAMILY SSF53335 512 735 2.74E-9 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_00075 cefed2acb53ec3930875ef1f52332fde 945 SUPERFAMILY SSF53335 91 631 1.53E-11 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_11805 cefed2acb53ec3930875ef1f52332fde 945 Pfam PF06634 Protein of unknown function (DUF1156) 19 71 5.4E-6 T 31-10-2018 IPR009537 Domain of unknown function DUF1156 DFR86_11805 cefed2acb53ec3930875ef1f52332fde 945 Gene3D G3DSA:3.40.50.150 61 131 3.5E-6 T 31-10-2018 DFR86_11805 cefed2acb53ec3930875ef1f52332fde 945 SUPERFAMILY SSF53335 512 735 2.74E-9 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_11805 cefed2acb53ec3930875ef1f52332fde 945 SUPERFAMILY SSF53335 91 631 1.53E-11 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_08120 f5d05e95e7b7a36e7bc4da00e31fbf6f 251 SUPERFAMILY SSF53448 4 245 1.88E-45 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_08120 f5d05e95e7b7a36e7bc4da00e31fbf6f 251 Pfam PF00483 Nucleotidyl transferase 4 244 1.3E-23 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR86_08120 f5d05e95e7b7a36e7bc4da00e31fbf6f 251 Gene3D G3DSA:3.90.550.10 1 249 5.5E-52 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_06210 a34803875c198f7818222958cebe037a 194 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 11 194 40.295 T 31-10-2018 IPR026018 Ribosomal protein S7, archaeal DFR86_06210 a34803875c198f7818222958cebe037a 194 ProSitePatterns PS00052 Ribosomal protein S7 signature. 60 86 - T 31-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06210 a34803875c198f7818222958cebe037a 194 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 10 194 6.3E-83 T 31-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06210 a34803875c198f7818222958cebe037a 194 Pfam PF00177 Ribosomal protein S7p/S5e 55 194 5.4E-43 T 31-10-2018 IPR023798 Ribosomal protein S7 domain DFR86_06210 a34803875c198f7818222958cebe037a 194 Gene3D G3DSA:1.10.455.10 1 194 8.2E-85 T 31-10-2018 IPR036823 Ribosomal protein S7 domain superfamily DFR86_06210 a34803875c198f7818222958cebe037a 194 SUPERFAMILY SSF47973 14 194 1.57E-61 T 31-10-2018 IPR036823 Ribosomal protein S7 domain superfamily DFR86_06210 a34803875c198f7818222958cebe037a 194 PIRSF PIRSF002122 2 194 2.4E-45 T 31-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 DFR86_10350 37678b01049b5a176ef385a60d261375 210 SUPERFAMILY SSF56281 11 206 8.91E-36 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_10350 37678b01049b5a176ef385a60d261375 210 Gene3D G3DSA:3.60.15.10 2 207 2.7E-37 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_10350 37678b01049b5a176ef385a60d261375 210 SMART SM00849 10 201 4.6E-21 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_10350 37678b01049b5a176ef385a60d261375 210 Pfam PF00753 Metallo-beta-lactamase superfamily 9 201 1.1E-21 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 Gene3D G3DSA:2.40.128.630 325 397 1.7E-13 T 31-10-2018 DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 Gene3D G3DSA:2.40.128.630 249 324 7.3E-14 T 31-10-2018 DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 Gene3D G3DSA:2.40.128.630 133 248 9.8E-17 T 31-10-2018 DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 Pfam PF13360 PQQ-like domain 250 391 3.9E-16 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 SUPERFAMILY SSF50998 229 393 1.39E-31 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 SMART SM00564 135 165 55.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 SMART SM00564 174 207 110.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 SMART SM00564 216 246 2.1 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 SMART SM00564 294 324 0.15 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 SMART SM00564 333 365 1.8E-10 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 SMART SM00564 254 285 0.012 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_00440 eb238246bb6eff25afbb96c57072253d 856 SUPERFAMILY SSF50998 53 275 9.1E-16 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR86_00135 26782c2f770ffeff09191f8e249666c6 237 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 113 225 9.4E-6 T 31-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal DFR86_00135 26782c2f770ffeff09191f8e249666c6 237 Gene3D G3DSA:3.30.70.1900 95 234 1.7E-8 T 31-10-2018 DFR86_01250 3723523bc5bce0c9a1a23aabc7e1326e 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 427 448 2.3E-7 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01250 3723523bc5bce0c9a1a23aabc7e1326e 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 66 89 2.3E-7 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01250 3723523bc5bce0c9a1a23aabc7e1326e 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 264 2.3E-7 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01250 3723523bc5bce0c9a1a23aabc7e1326e 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 313 334 2.3E-7 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01250 3723523bc5bce0c9a1a23aabc7e1326e 541 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 2.3E-7 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01250 3723523bc5bce0c9a1a23aabc7e1326e 541 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 471 7.6E-76 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01250 3723523bc5bce0c9a1a23aabc7e1326e 541 Gene3D G3DSA:1.20.210.10 14 524 2.2E-84 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_01250 3723523bc5bce0c9a1a23aabc7e1326e 541 SUPERFAMILY SSF81442 25 494 9.42E-90 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_02935 74c7f6d2c7c28396ba065c6d9a2a0456 428 Pfam PF00120 Glutamine synthetase, catalytic domain 108 423 2.1E-74 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_02935 74c7f6d2c7c28396ba065c6d9a2a0456 428 Gene3D G3DSA:3.10.20.70 1 107 8.7E-10 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_02935 74c7f6d2c7c28396ba065c6d9a2a0456 428 SUPERFAMILY SSF54368 3 103 2.22E-16 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_02935 74c7f6d2c7c28396ba065c6d9a2a0456 428 SMART SM01230 107 352 4.0E-65 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR86_02935 74c7f6d2c7c28396ba065c6d9a2a0456 428 SUPERFAMILY SSF55931 107 424 5.1E-75 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR86_02935 74c7f6d2c7c28396ba065c6d9a2a0456 428 Gene3D G3DSA:3.30.590.10 110 426 2.6E-80 T 31-10-2018 DFR86_09620 259d749a246af9315995005c90c25051 361 Pfam PF01513 ATP-NAD kinase 2 356 1.9E-53 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 DFR86_09620 259d749a246af9315995005c90c25051 361 SUPERFAMILY SSF111331 87 131 5.63E-6 T 31-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily DFR86_09620 259d749a246af9315995005c90c25051 361 PIRSF PIRSF016907 1 359 3.3E-123 T 31-10-2018 IPR011386 Putative ATP-NAD kinase DFR86_09620 259d749a246af9315995005c90c25051 361 Gene3D G3DSA:3.40.50.10330 56 168 2.8E-5 T 31-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 DFR86_11440 8c95b0e3d5ce232ccaf49641f8218a54 379 Gene3D G3DSA:1.10.3740.10 204 377 2.6E-145 T 31-10-2018 IPR027419 CRISPR-associated protein Csx1, C-terminal DFR86_11440 8c95b0e3d5ce232ccaf49641f8218a54 379 SUPERFAMILY SSF160980 1 377 3.92E-83 T 31-10-2018 DFR86_11440 8c95b0e3d5ce232ccaf49641f8218a54 379 TIGRFAM TIGR01897 cas_MJ1666: CRISPR-associated protein, MJ1666 family 3 376 1.6E-76 T 31-10-2018 IPR010171 CRISPR-associated protein, MJ1666 DFR86_11440 8c95b0e3d5ce232ccaf49641f8218a54 379 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 5 349 9.0E-15 T 31-10-2018 IPR019016 CRISPR-associated DxTHG protein DFR86_11440 8c95b0e3d5ce232ccaf49641f8218a54 379 Gene3D G3DSA:3.40.50.10640 3 268 2.6E-145 T 31-10-2018 DFR86_11440 8c95b0e3d5ce232ccaf49641f8218a54 379 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 120 140 1.3E-9 T 31-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site DFR86_06995 682aee02489c0944355affd19b3e786b 126 SUPERFAMILY SSF158997 54 101 1.02E-13 T 31-10-2018 DFR86_06995 682aee02489c0944355affd19b3e786b 126 Pfam PF03966 Trm112p-like protein 2 85 3.2E-19 T 31-10-2018 IPR005651 Trm112-like DFR86_06395 b381cd4ea3e9fa5a3dfdb9978ead8da8 174 Gene3D G3DSA:3.40.50.620 2 174 5.7E-55 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_06395 b381cd4ea3e9fa5a3dfdb9978ead8da8 174 SUPERFAMILY SSF52374 3 164 3.38E-34 T 31-10-2018 DFR86_06395 b381cd4ea3e9fa5a3dfdb9978ead8da8 174 Pfam PF01467 Cytidylyltransferase-like 5 135 2.0E-20 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR86_06395 b381cd4ea3e9fa5a3dfdb9978ead8da8 174 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 62 3.1E-16 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR86_06395 b381cd4ea3e9fa5a3dfdb9978ead8da8 174 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 174 84.753 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 DFR86_06395 b381cd4ea3e9fa5a3dfdb9978ead8da8 174 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 3 170 1.0E-76 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 DFR86_02440 e0219eaa5acc4a2d62d84e371ba499e3 510 SUPERFAMILY SSF51621 122 461 1.99E-38 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR86_02440 e0219eaa5acc4a2d62d84e371ba499e3 510 Pfam PF14010 Phosphoenolpyruvate carboxylase 4 510 2.0E-210 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DFR86_02440 e0219eaa5acc4a2d62d84e371ba499e3 510 PIRSF PIRSF006677 1 510 1.9E-198 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DFR86_02440 e0219eaa5acc4a2d62d84e371ba499e3 510 TIGRFAM TIGR02751 PEPCase_arch: phosphoenolpyruvate carboxylase 4 510 7.5E-212 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DFR86_02440 e0219eaa5acc4a2d62d84e371ba499e3 510 Hamap MF_01904 Phosphoenolpyruvate carboxylase [ppcA]. 3 510 39.685 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DFR86_00350 d90bb4233982a287039f0cc2e796fa19 896 Gene3D G3DSA:3.20.110.20 368 679 1.8E-27 T 31-10-2018 DFR86_00350 d90bb4233982a287039f0cc2e796fa19 896 PIRSF PIRSF032656 1 896 0.0 T 31-10-2018 IPR017002 Glycoside hydrolase, family 57, Saci1162, predicted DFR86_00350 d90bb4233982a287039f0cc2e796fa19 896 SUPERFAMILY SSF88713 336 665 9.78E-72 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DFR86_00350 d90bb4233982a287039f0cc2e796fa19 896 Pfam PF03065 Glycosyl hydrolase family 57 341 652 4.8E-45 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 PRINTS PR00143 Citrate synthase signature 172 187 5.2E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 PRINTS PR00143 Citrate synthase signature 123 136 5.2E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 PRINTS PR00143 Citrate synthase signature 194 222 5.2E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 PRINTS PR00143 Citrate synthase signature 308 324 5.2E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 PRINTS PR00143 Citrate synthase signature 248 268 5.2E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 PRINTS PR00143 Citrate synthase signature 328 342 5.2E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 Gene3D G3DSA:1.10.230.10 220 322 1.6E-129 T 31-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 6 376 1.4E-142 T 31-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 SUPERFAMILY SSF48256 4 376 6.41E-128 T 31-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 Gene3D G3DSA:1.10.580.10 21 347 1.6E-129 T 31-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 ProSitePatterns PS00480 Citrate synthase signature. 255 267 - T 31-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 PIRSF PIRSF001369 1 377 2.6E-150 T 31-10-2018 IPR024176 Citrate synthase, bacterial-type DFR86_01350 169b12444433ae826d5a36be5cc656b4 377 Pfam PF00285 Citrate synthase, C-terminal domain 7 359 8.4E-120 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR86_09440 18ac8b2d78c328d7f90c1a815d45b465 261 Pfam PF03357 Snf7 30 191 1.5E-6 T 31-10-2018 IPR005024 Snf7 family GO:0007034 DFR86_09440 18ac8b2d78c328d7f90c1a815d45b465 261 Gene3D G3DSA:1.10.10.10 207 261 7.3E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10945 8a931e92b024854c99d4d45088432855 111 PIRSF PIRSF006821 1 109 4.0E-51 T 31-10-2018 IPR018685 Protein of unknown function DUF2173 DFR86_10945 8a931e92b024854c99d4d45088432855 111 Pfam PF09941 Uncharacterized conserved protein (DUF2173) 3 106 5.7E-41 T 31-10-2018 IPR018685 Protein of unknown function DUF2173 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 SMART SM00485 1 103 4.8E-46 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 351 136.214 T 31-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 SUPERFAMILY SSF47807 223 351 3.14E-27 T 31-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 ProSitePatterns PS00841 XPG protein signature 1. 75 89 - T 31-10-2018 IPR019974 XPG conserved site GO:0016788 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 Pfam PF00752 XPG N-terminal domain 5 102 1.7E-22 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 SMART SM00484 142 223 1.0E-28 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 SMART SM00279 225 259 2.6E-9 T 31-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 Gene3D G3DSA:3.40.50.1010 3 351 1.0E-109 T 31-10-2018 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 351 3.1E-140 T 31-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 SUPERFAMILY SSF88723 5 238 8.5E-67 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 SMART SM00475 24 310 0.0036 T 31-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 Pfam PF00867 XPG I-region 143 238 1.8E-27 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 162 182 3.9E-31 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 23 37 3.9E-31 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 141 158 3.9E-31 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 77 96 3.9E-31 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 DFR86_07140 d661f3cb943b6bf890f3f7567b0147fe 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 228 243 3.9E-31 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 DFR86_06125 4b30adfa5e5944c88aed550ccdfcef88 154 Gene3D G3DSA:3.40.50.960 1 154 1.3E-49 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_06125 4b30adfa5e5944c88aed550ccdfcef88 154 TIGRFAM TIGR01506 ribC_arch: riboflavin synthase 4 153 5.5E-63 T 31-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_06125 4b30adfa5e5944c88aed550ccdfcef88 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 16 108 5.3E-12 T 31-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_06125 4b30adfa5e5944c88aed550ccdfcef88 154 SUPERFAMILY SSF52121 3 128 8.63E-26 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_06125 4b30adfa5e5944c88aed550ccdfcef88 154 PIRSF PIRSF015750 1 154 1.7E-71 T 31-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR86_01105 629873844791fcc654e91f27ea605735 138 SUPERFAMILY SSF51735 7 135 9.06E-38 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_01105 629873844791fcc654e91f27ea605735 138 SMART SM00881 12 109 3.5E-24 T 31-10-2018 IPR003781 CoA-binding GO:0048037 DFR86_01105 629873844791fcc654e91f27ea605735 138 Gene3D G3DSA:3.40.50.720 2 138 1.6E-42 T 31-10-2018 DFR86_01105 629873844791fcc654e91f27ea605735 138 Pfam PF13380 CoA binding domain 16 135 4.7E-37 T 31-10-2018 IPR003781 CoA-binding GO:0048037 DFR86_02685 296107edc30d864a301405ce6475d13c 333 Gene3D G3DSA:3.90.180.10 1 333 5.6E-94 T 31-10-2018 DFR86_02685 296107edc30d864a301405ce6475d13c 333 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 163 184 - T 31-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 DFR86_02685 296107edc30d864a301405ce6475d13c 333 Pfam PF00107 Zinc-binding dehydrogenase 174 294 3.6E-23 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR86_02685 296107edc30d864a301405ce6475d13c 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 5.6E-25 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR86_02685 296107edc30d864a301405ce6475d13c 333 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 DFR86_02685 296107edc30d864a301405ce6475d13c 333 SUPERFAMILY SSF50129 1 170 3.2E-46 T 31-10-2018 IPR011032 GroES-like superfamily DFR86_02685 296107edc30d864a301405ce6475d13c 333 SUPERFAMILY SSF51735 144 304 3.04E-34 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_02685 296107edc30d864a301405ce6475d13c 333 SMART SM00829 8 331 9.1E-13 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR86_05900 6586fe392be323f6c04e6393d016ea45 100 PIRSF PIRSF037511 3 98 5.8E-29 T 31-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 DFR86_05900 6586fe392be323f6c04e6393d016ea45 100 Hamap MF_00604 Protein translation factor SUI1 homolog. 5 94 26.263 T 31-10-2018 IPR022851 Translation factor SUI1 homolog, archaea DFR86_05900 6586fe392be323f6c04e6393d016ea45 100 Gene3D G3DSA:3.30.780.10 21 99 6.8E-31 T 31-10-2018 DFR86_05900 6586fe392be323f6c04e6393d016ea45 100 SUPERFAMILY SSF55159 17 97 2.22E-26 T 31-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 DFR86_05900 6586fe392be323f6c04e6393d016ea45 100 Pfam PF01253 Translation initiation factor SUI1 22 92 4.6E-22 T 31-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 DFR86_05900 6586fe392be323f6c04e6393d016ea45 100 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 6 96 2.5E-35 T 31-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 DFR86_08935 b0e477a7112d278795d4c3af10a17a73 649 Gene3D G3DSA:3.60.20.10 115 347 2.0E-31 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_08935 b0e477a7112d278795d4c3af10a17a73 649 Gene3D G3DSA:2.160.20.60 360 608 1.7E-21 T 31-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 DFR86_08935 b0e477a7112d278795d4c3af10a17a73 649 SUPERFAMILY SSF56235 7 352 1.72E-52 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_08935 b0e477a7112d278795d4c3af10a17a73 649 Pfam PF01493 GXGXG motif 379 536 7.6E-21 T 31-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 DFR86_08935 b0e477a7112d278795d4c3af10a17a73 649 SUPERFAMILY SSF69336 358 566 3.53E-42 T 31-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 DFR86_08935 b0e477a7112d278795d4c3af10a17a73 649 PIRSF PIRSF036632 1 649 3.4E-302 T 31-10-2018 IPR012075 Glutamate synthase, large subunit domains 1/3 fusion DFR86_03200 4d786e8edba3191950a971a7d7ff1947 355 SUPERFAMILY SSF81271 276 353 3.53E-18 T 31-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 DFR86_03200 4d786e8edba3191950a971a7d7ff1947 355 Gene3D G3DSA:3.10.20.30 273 355 3.4E-30 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR86_03200 4d786e8edba3191950a971a7d7ff1947 355 Pfam PF02824 TGS domain 282 353 1.5E-20 T 31-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 DFR86_02780 71e659aac066d408ac28ef16bb32ea24 361 Pfam PF01266 FAD dependent oxidoreductase 2 344 6.8E-40 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DFR86_02780 71e659aac066d408ac28ef16bb32ea24 361 Gene3D G3DSA:3.50.50.60 171 346 1.8E-10 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_02780 71e659aac066d408ac28ef16bb32ea24 361 Gene3D G3DSA:3.30.9.10 158 306 1.8E-10 T 31-10-2018 DFR86_02780 71e659aac066d408ac28ef16bb32ea24 361 Gene3D G3DSA:3.50.50.60 1 75 1.4E-11 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_02780 71e659aac066d408ac28ef16bb32ea24 361 SUPERFAMILY SSF51971 1 351 3.06E-21 T 31-10-2018 DFR86_03655 08949b09e06217a8e2240ebaf788888f 322 SUPERFAMILY SSF53807 40 298 5.1E-38 T 31-10-2018 DFR86_03655 08949b09e06217a8e2240ebaf788888f 322 Gene3D G3DSA:3.40.50.1980 28 165 1.2E-17 T 31-10-2018 DFR86_03655 08949b09e06217a8e2240ebaf788888f 322 Gene3D G3DSA:3.40.50.1980 166 299 1.9E-15 T 31-10-2018 DFR86_03655 08949b09e06217a8e2240ebaf788888f 322 Pfam PF01497 Periplasmic binding protein 41 275 2.1E-18 T 31-10-2018 IPR002491 ABC transporter periplasmic binding domain DFR86_11120 436189d0202cc64099fabf247cda0023 668 SUPERFAMILY SSF51004 55 304 9.42E-31 T 31-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily DFR86_11120 436189d0202cc64099fabf247cda0023 668 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 56 93 9.8E-10 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_11120 436189d0202cc64099fabf247cda0023 668 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 94 133 2.7E-8 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR86_11120 436189d0202cc64099fabf247cda0023 668 Gene3D G3DSA:2.130.10.10 209 361 3.3E-9 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_11120 436189d0202cc64099fabf247cda0023 668 Gene3D G3DSA:2.130.10.10 27 208 9.4E-29 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_03640 73715fdf448e75907a3910ad63e0faca 118 SMART SM00418 13 93 6.9E-27 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_03640 73715fdf448e75907a3910ad63e0faca 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 2.3E-14 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_03640 73715fdf448e75907a3910ad63e0faca 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 2.3E-14 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_03640 73715fdf448e75907a3910ad63e0faca 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 2.3E-14 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_03640 73715fdf448e75907a3910ad63e0faca 118 SUPERFAMILY SSF46785 8 94 5.45E-22 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_03640 73715fdf448e75907a3910ad63e0faca 118 Gene3D G3DSA:1.10.10.10 2 102 9.1E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_03640 73715fdf448e75907a3910ad63e0faca 118 Pfam PF01022 Bacterial regulatory protein, arsR family 20 67 2.4E-16 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_03240 dab42ef041b8c272a8cf536ff5b8d0e1 249 SUPERFAMILY SSF56112 25 239 7.74E-24 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR86_03240 dab42ef041b8c272a8cf536ff5b8d0e1 249 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 181 192 - T 31-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 DFR86_03240 dab42ef041b8c272a8cf536ff5b8d0e1 249 SMART SM00090 13 247 5.3E-83 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 DFR86_03240 dab42ef041b8c272a8cf536ff5b8d0e1 249 Pfam PF01163 RIO1 family 55 240 2.2E-63 T 31-10-2018 DFR86_03240 dab42ef041b8c272a8cf536ff5b8d0e1 249 Gene3D G3DSA:3.30.200.20 45 143 1.1E-12 T 31-10-2018 DFR86_03240 dab42ef041b8c272a8cf536ff5b8d0e1 249 Gene3D G3DSA:1.10.510.10 149 248 2.8E-29 T 31-10-2018 DFR86_04280 22a4191b9eaa8a45d3f7c0856964ad88 518 PIRSF PIRSF006060 2 517 1.4E-23 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04280 22a4191b9eaa8a45d3f7c0856964ad88 518 Gene3D G3DSA:1.20.1740.10 21 513 4.4E-9 T 31-10-2018 DFR86_02770 c7b4ef26d87c37f8493db940ff4199eb 68 SUPERFAMILY SSF54285 6 68 4.22E-11 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp DFR86_02770 c7b4ef26d87c37f8493db940ff4199eb 68 Gene3D G3DSA:3.10.20.30 1 68 4.6E-16 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR86_02770 c7b4ef26d87c37f8493db940ff4199eb 68 Pfam PF02597 ThiS family 13 68 4.4E-7 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 Gene3D G3DSA:3.10.580.10 173 234 4.0E-10 T 31-10-2018 DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 Gene3D G3DSA:3.10.580.10 65 172 1.7E-13 T 31-10-2018 DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 Gene3D G3DSA:3.10.580.10 3 64 1.1E-5 T 31-10-2018 DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 SMART SM00116 7 54 0.021 T 31-10-2018 IPR000644 CBS domain DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 SMART SM00116 185 228 0.019 T 31-10-2018 IPR000644 CBS domain DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 SMART SM00116 123 169 5.8E-6 T 31-10-2018 IPR000644 CBS domain DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 SUPERFAMILY SSF54631 6 104 4.67E-11 T 31-10-2018 DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 Pfam PF00571 CBS domain 6 53 2.4E-6 T 31-10-2018 IPR000644 CBS domain DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 Pfam PF00571 CBS domain 178 227 3.7E-8 T 31-10-2018 IPR000644 CBS domain DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 Pfam PF00571 CBS domain 125 167 1.7E-6 T 31-10-2018 IPR000644 CBS domain DFR86_05495 ae1ad6659e8b9ef545c5ac5aeaaaa42e 234 SUPERFAMILY SSF54631 98 230 8.18E-24 T 31-10-2018 DFR86_07565 2ee08344deb5339f4d16b5de68d041cd 305 Gene3D G3DSA:3.90.550.10 2 237 1.8E-18 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_07565 2ee08344deb5339f4d16b5de68d041cd 305 SUPERFAMILY SSF53448 5 261 9.24E-21 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_07565 2ee08344deb5339f4d16b5de68d041cd 305 Pfam PF00535 Glycosyl transferase family 2 5 126 2.0E-11 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_01220 5f094d4c39b779f30ef887236bb903bb 271 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 28 265 1.6E-89 T 31-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 DFR86_01220 5f094d4c39b779f30ef887236bb903bb 271 Gene3D G3DSA:3.40.1010.10 18 137 5.6E-32 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR86_01220 5f094d4c39b779f30ef887236bb903bb 271 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 27 231 2.3E-39 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR86_01220 5f094d4c39b779f30ef887236bb903bb 271 SUPERFAMILY SSF53790 26 269 2.22E-52 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR86_01220 5f094d4c39b779f30ef887236bb903bb 271 Gene3D G3DSA:3.30.950.10 138 264 3.1E-40 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 DFR86_07380 7a80fac1b12aac152d1540ff98307921 156 PIRSF PIRSF001338 1 155 1.3E-71 T 31-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 DFR86_07380 7a80fac1b12aac152d1540ff98307921 156 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 4 154 3.3E-69 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 DFR86_07380 7a80fac1b12aac152d1540ff98307921 156 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 4 155 33.475 T 31-10-2018 IPR033747 Class I PurE DFR86_07380 7a80fac1b12aac152d1540ff98307921 156 SUPERFAMILY SSF52255 2 154 2.62E-67 T 31-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 DFR86_07380 7a80fac1b12aac152d1540ff98307921 156 Pfam PF00731 AIR carboxylase 4 149 3.7E-69 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 DFR86_07380 7a80fac1b12aac152d1540ff98307921 156 SMART SM01001 2 151 2.7E-103 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 DFR86_07380 7a80fac1b12aac152d1540ff98307921 156 Gene3D G3DSA:3.40.50.7700 1 156 7.6E-73 T 31-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 DFR86_00825 507afd367b95b4884c3ec18823befeaa 300 Pfam PF03595 Voltage-dependent anion channel 10 294 5.3E-14 T 31-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 DFR86_05995 25c57675286a8e244748afa7e2022aa8 322 Pfam PF01992 ATP synthase (C/AC39) subunit 13 315 6.5E-24 T 31-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_05995 25c57675286a8e244748afa7e2022aa8 322 SUPERFAMILY SSF103486 7 317 3.27E-12 T 31-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_03120 4b3e7432686621ccb936614ab2b3559f 76 Gene3D G3DSA:3.30.70.920 4 74 1.4E-18 T 31-10-2018 DFR86_03120 4b3e7432686621ccb936614ab2b3559f 76 Pfam PF01037 Lrp/AsnC ligand binding domain 19 76 1.2E-9 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR86_03120 4b3e7432686621ccb936614ab2b3559f 76 SUPERFAMILY SSF54909 3 76 1.74E-11 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR86_03955 c504348cb9c252c5861a55a5b8451c66 512 SUPERFAMILY SSF56762 2 500 5.23E-58 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_03955 c504348cb9c252c5861a55a5b8451c66 512 Gene3D G3DSA:1.10.645.10 2 500 1.1E-109 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_03955 c504348cb9c252c5861a55a5b8451c66 512 Pfam PF00374 Nickel-dependent hydrogenase 38 128 1.6E-12 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR86_03955 c504348cb9c252c5861a55a5b8451c66 512 Pfam PF00374 Nickel-dependent hydrogenase 416 500 1.5E-19 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR86_08580 dcfcf23f40e96dd65f60f5c4bd12089e 267 Gene3D G3DSA:1.10.1580.10 172 248 1.3E-6 T 31-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily DFR86_08580 dcfcf23f40e96dd65f60f5c4bd12089e 267 SUPERFAMILY SSF52540 4 222 1.0E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08580 dcfcf23f40e96dd65f60f5c4bd12089e 267 PIRSF PIRSF006230 1 259 1.3E-51 T 31-10-2018 IPR016478 GTPase, MTG1 DFR86_08580 dcfcf23f40e96dd65f60f5c4bd12089e 267 Pfam PF01926 50S ribosome-binding GTPase 101 187 5.5E-12 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_08580 dcfcf23f40e96dd65f60f5c4bd12089e 267 Gene3D G3DSA:3.40.50.300 3 160 3.3E-40 T 31-10-2018 DFR86_01340 85c7dd27db03bd0d7f0075fce7f166aa 277 Pfam PF13714 Phosphoenolpyruvate phosphomutase 5 236 7.7E-50 T 31-10-2018 DFR86_01340 85c7dd27db03bd0d7f0075fce7f166aa 277 Gene3D G3DSA:3.20.20.60 1 277 8.5E-100 T 31-10-2018 DFR86_01340 85c7dd27db03bd0d7f0075fce7f166aa 277 SUPERFAMILY SSF51621 4 272 1.7E-91 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR86_01340 85c7dd27db03bd0d7f0075fce7f166aa 277 ProSitePatterns PS00161 Isocitrate lyase signature. 106 111 - T 31-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 DFR86_01340 85c7dd27db03bd0d7f0075fce7f166aa 277 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 8 275 2.7E-114 T 31-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 DFR86_01850 7d5cacac42ca136cc6f129e84a968987 109 Pfam PF02635 DsrE/DsrF-like family 18 108 5.6E-10 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR86_01850 7d5cacac42ca136cc6f129e84a968987 109 Gene3D G3DSA:3.40.1260.10 2 109 2.4E-34 T 31-10-2018 IPR027396 DsrEFH-like DFR86_01850 7d5cacac42ca136cc6f129e84a968987 109 SUPERFAMILY SSF75169 1 107 1.71E-25 T 31-10-2018 IPR027396 DsrEFH-like DFR86_07720 f010ba73c3ab15980c6e1937074a6b6e 184 Pfam PF01810 LysE type translocator 12 182 8.7E-12 T 31-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 DFR86_06750 9934f450c18bac9e31d63a6fd8d6d979 198 SUPERFAMILY SSF50475 6 178 1.06E-29 T 31-10-2018 DFR86_06750 9934f450c18bac9e31d63a6fd8d6d979 198 Gene3D G3DSA:2.30.110.10 9 130 1.1E-20 T 31-10-2018 IPR012349 FMN-binding split barrel GO:0048037 DFR86_06750 9934f450c18bac9e31d63a6fd8d6d979 198 Pfam PF04289 Protein of unknown function (DUF447) 17 181 1.7E-32 T 31-10-2018 IPR007386 Protein of unknown function DUF447 DFR86_06750 9934f450c18bac9e31d63a6fd8d6d979 198 PIRSF PIRSF018747 5 193 5.8E-9 T 31-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 DFR86_11160 64bd49d72a517bf69ffc6756694b010c 744 Gene3D G3DSA:3.30.365.10 190 283 1.6E-66 T 31-10-2018 DFR86_11160 64bd49d72a517bf69ffc6756694b010c 744 SMART SM01008 18 135 1.6E-45 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_11160 64bd49d72a517bf69ffc6756694b010c 744 Gene3D G3DSA:3.30.365.10 368 728 9.3E-112 T 31-10-2018 DFR86_11160 64bd49d72a517bf69ffc6756694b010c 744 SUPERFAMILY SSF56003 127 744 5.63E-181 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR86_11160 64bd49d72a517bf69ffc6756694b010c 744 Gene3D G3DSA:3.30.365.10 148 359 1.6E-66 T 31-10-2018 DFR86_11160 64bd49d72a517bf69ffc6756694b010c 744 SUPERFAMILY SSF54665 2 153 3.53E-40 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR86_11160 64bd49d72a517bf69ffc6756694b010c 744 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 134 5.5E-27 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_11160 64bd49d72a517bf69ffc6756694b010c 744 Gene3D G3DSA:3.90.1170.50 1 134 3.1E-38 T 31-10-2018 DFR86_11160 64bd49d72a517bf69ffc6756694b010c 744 Gene3D G3DSA:3.30.365.10 455 604 9.3E-112 T 31-10-2018 DFR86_11160 64bd49d72a517bf69ffc6756694b010c 744 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 150 687 1.5E-158 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR86_09205 2f33130d7a40e06a8abcb42ffdbe3a24 118 Hamap MF_00026 DNA-binding protein . 10 112 14.949 T 31-10-2018 IPR022889 DNA-binding protein, archaeal DFR86_09205 2f33130d7a40e06a8abcb42ffdbe3a24 118 Pfam PF01984 Double-stranded DNA-binding domain 13 114 1.7E-24 T 31-10-2018 IPR002836 PDCD5-like GO:0003677 DFR86_09205 2f33130d7a40e06a8abcb42ffdbe3a24 118 SUPERFAMILY SSF46950 19 111 1.57E-24 T 31-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 DFR86_09205 2f33130d7a40e06a8abcb42ffdbe3a24 118 PIRSF PIRSF015730 6 118 4.4E-31 T 31-10-2018 IPR002836 PDCD5-like GO:0003677 DFR86_09205 2f33130d7a40e06a8abcb42ffdbe3a24 118 Gene3D G3DSA:1.10.8.140 31 113 3.2E-25 T 31-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 DFR86_10120 73a6c886ed71e6cf8dfad1b7b5c83bdd 313 SUPERFAMILY SSF53756 4 262 3.77E-14 T 31-10-2018 DFR86_10120 73a6c886ed71e6cf8dfad1b7b5c83bdd 313 Gene3D G3DSA:3.40.50.2000 164 294 1.6E-8 T 31-10-2018 DFR86_10120 73a6c886ed71e6cf8dfad1b7b5c83bdd 313 Gene3D G3DSA:3.40.50.2000 2 163 2.8E-5 T 31-10-2018 DFR86_10120 73a6c886ed71e6cf8dfad1b7b5c83bdd 313 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 166 263 5.8E-9 T 31-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 DFR86_06685 ec1464c712adc29da5e35096161f1123 242 Gene3D G3DSA:3.60.20.10 5 241 1.3E-80 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_06685 ec1464c712adc29da5e35096161f1123 242 Pfam PF00227 Proteasome subunit 33 218 2.1E-58 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_06685 ec1464c712adc29da5e35096161f1123 242 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 238 44.395 T 31-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 DFR86_06685 ec1464c712adc29da5e35096161f1123 242 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_06685 ec1464c712adc29da5e35096161f1123 242 SMART SM00948 10 32 7.3E-10 T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_06685 ec1464c712adc29da5e35096161f1123 242 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 236 5.2E-100 T 31-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 DFR86_06685 ec1464c712adc29da5e35096161f1123 242 SUPERFAMILY SSF56235 8 240 2.04E-75 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_06685 ec1464c712adc29da5e35096161f1123 242 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 5.2E-13 T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_10235 5bccc04b257f283dd78f7218d881c865 259 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.0E-14 T 31-10-2018 DFR86_10235 5bccc04b257f283dd78f7218d881c865 259 Pfam PF13412 Winged helix-turn-helix DNA-binding 131 174 1.2E-8 T 31-10-2018 DFR86_10235 5bccc04b257f283dd78f7218d881c865 259 SUPERFAMILY SSF46785 130 184 4.12E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_10235 5bccc04b257f283dd78f7218d881c865 259 SUPERFAMILY SSF46785 1 57 5.26E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_10235 5bccc04b257f283dd78f7218d881c865 259 SMART SM00344 1 106 4.7E-5 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR86_10235 5bccc04b257f283dd78f7218d881c865 259 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.7E-8 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_10235 5bccc04b257f283dd78f7218d881c865 259 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.7E-8 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_10235 5bccc04b257f283dd78f7218d881c865 259 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.7E-8 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR86_10235 5bccc04b257f283dd78f7218d881c865 259 Gene3D G3DSA:1.10.10.10 1 51 1.0E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10235 5bccc04b257f283dd78f7218d881c865 259 Gene3D G3DSA:1.10.10.10 130 176 1.5E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_08265 0a12c4740980249f9a59d06d88220be9 182 SMART SM00835 76 179 6.7E-4 T 31-10-2018 IPR006045 Cupin 1 GO:0045735 DFR86_08265 0a12c4740980249f9a59d06d88220be9 182 Pfam PF07883 Cupin domain 97 164 2.1E-16 T 31-10-2018 IPR013096 Cupin 2, conserved barrel DFR86_08265 0a12c4740980249f9a59d06d88220be9 182 Gene3D G3DSA:2.60.120.10 40 182 2.4E-36 T 31-10-2018 IPR014710 RmlC-like jelly roll fold DFR86_08265 0a12c4740980249f9a59d06d88220be9 182 SUPERFAMILY SSF51182 55 176 1.17E-32 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily DFR86_07560 4a11c1d7830638bf62ceedc8c160cec0 601 Gene3D G3DSA:1.50.10.10 243 597 4.5E-78 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR86_07560 4a11c1d7830638bf62ceedc8c160cec0 601 SUPERFAMILY SSF48208 220 596 1.27E-94 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR86_07560 4a11c1d7830638bf62ceedc8c160cec0 601 Pfam PF00723 Glycosyl hydrolases family 15 344 540 1.3E-16 T 31-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 DFR86_01405 ee6952da0f0e85c3973d656bfcb9bada 275 SUPERFAMILY SSF103481 176 271 7.19E-14 T 31-10-2018 DFR86_01405 ee6952da0f0e85c3973d656bfcb9bada 275 SUPERFAMILY SSF103481 57 130 1.96E-8 T 31-10-2018 DFR86_01405 ee6952da0f0e85c3973d656bfcb9bada 275 Pfam PF00892 EamA-like transporter family 140 269 5.3E-17 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR86_01405 ee6952da0f0e85c3973d656bfcb9bada 275 Pfam PF00892 EamA-like transporter family 5 131 4.5E-8 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR86_05730 15dee1adee2ae9d71062133768bfb599 317 Pfam PF00953 Glycosyl transferase family 4 72 228 3.0E-32 T 31-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 DFR86_08840 aa497e09b72d9fc7f8c0cf822c798ecb 262 Pfam PF00288 GHMP kinases N terminal domain 60 126 4.8E-9 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR86_08840 aa497e09b72d9fc7f8c0cf822c798ecb 262 PIRSF PIRSF005758 1 261 2.5E-78 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 DFR86_08840 aa497e09b72d9fc7f8c0cf822c798ecb 262 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 3 251 1.6E-68 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 DFR86_08840 aa497e09b72d9fc7f8c0cf822c798ecb 262 SUPERFAMILY SSF54211 19 153 1.37E-15 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_08840 aa497e09b72d9fc7f8c0cf822c798ecb 262 Gene3D G3DSA:3.30.230.10 7 139 1.7E-15 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR86_08840 aa497e09b72d9fc7f8c0cf822c798ecb 262 Hamap MF_00370 Shikimate kinase [aroK]. 1 262 79.738 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 DFR86_08840 aa497e09b72d9fc7f8c0cf822c798ecb 262 SUPERFAMILY SSF55060 212 252 5.25E-5 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR86_10355 763a9021516e675b2aa2229747d2bd8f 125 SUPERFAMILY SSF50249 2 113 6.43E-27 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_10355 763a9021516e675b2aa2229747d2bd8f 125 Gene3D G3DSA:2.40.50.140 8 108 1.3E-30 T 31-10-2018 DFR86_06885 a145730956a89ce82da7a82100a2e549 461 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 31-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_06885 a145730956a89ce82da7a82100a2e549 461 SUPERFAMILY SSF103491 6 445 1.96E-90 T 31-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_06885 a145730956a89ce82da7a82100a2e549 461 ProSitePatterns PS00756 Protein secY signature 2. 161 179 - T 31-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_06885 a145730956a89ce82da7a82100a2e549 461 Gene3D G3DSA:1.10.3370.10 5 461 4.0E-124 T 31-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_06885 a145730956a89ce82da7a82100a2e549 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 169 192 6.8E-5 T 31-10-2018 DFR86_06885 a145730956a89ce82da7a82100a2e549 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 6.8E-5 T 31-10-2018 DFR86_06885 a145730956a89ce82da7a82100a2e549 461 PRINTS PR00303 Preprotein translocase SecY subunit signature 425 443 6.8E-5 T 31-10-2018 DFR86_06885 a145730956a89ce82da7a82100a2e549 461 PIRSF PIRSF004557 4 461 1.2E-96 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_06885 a145730956a89ce82da7a82100a2e549 461 Pfam PF10559 Plug domain of Sec61p 38 71 5.7E-9 T 31-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_06885 a145730956a89ce82da7a82100a2e549 461 Pfam PF00344 SecY translocase 72 440 1.5E-56 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_08385 f6913e01b0d3dab0f52e4aaad4e7f616 101 SMART SM00418 16 92 0.0022 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_08385 f6913e01b0d3dab0f52e4aaad4e7f616 101 SUPERFAMILY SSF46785 25 86 1.18E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_08385 f6913e01b0d3dab0f52e4aaad4e7f616 101 Pfam PF01022 Bacterial regulatory protein, arsR family 25 69 2.0E-10 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_08385 f6913e01b0d3dab0f52e4aaad4e7f616 101 Gene3D G3DSA:1.10.10.10 1 99 2.9E-14 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10660 c18b59fca58afa447ca85dbbea577622 546 Gene3D G3DSA:1.20.810.10 1 386 1.2E-76 T 31-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 DFR86_10660 c18b59fca58afa447ca85dbbea577622 546 SUPERFAMILY SSF81342 15 253 3.77E-45 T 31-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 DFR86_10660 c18b59fca58afa447ca85dbbea577622 546 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 89 273 1.5E-56 T 31-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 DFR86_10660 c18b59fca58afa447ca85dbbea577622 546 SUPERFAMILY SSF81648 215 367 5.07E-18 T 31-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 DFR86_02535 e8be8623f212e807e94e1729027da2b7 210 SMART SM00855 3 150 1.4E-11 T 31-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 DFR86_02535 e8be8623f212e807e94e1729027da2b7 210 PIRSF PIRSF000709 2 89 4.6E-4 T 31-10-2018 DFR86_02535 e8be8623f212e807e94e1729027da2b7 210 PIRSF PIRSF000709 116 189 4.7 T 31-10-2018 DFR86_02535 e8be8623f212e807e94e1729027da2b7 210 Gene3D G3DSA:3.40.50.1240 1 195 1.9E-38 T 31-10-2018 IPR029033 Histidine phosphatase superfamily DFR86_02535 e8be8623f212e807e94e1729027da2b7 210 SUPERFAMILY SSF53254 1 184 2.09E-38 T 31-10-2018 IPR029033 Histidine phosphatase superfamily DFR86_02535 e8be8623f212e807e94e1729027da2b7 210 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 181 5.0E-35 T 31-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 DFR86_04265 54590de7b61627415e21d4e0692d135b 639 Gene3D G3DSA:3.30.365.10 379 480 3.6E-20 T 31-10-2018 DFR86_04265 54590de7b61627415e21d4e0692d135b 639 SMART SM01008 3 100 4.4E-5 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_04265 54590de7b61627415e21d4e0692d135b 639 Gene3D G3DSA:3.30.365.10 354 378 3.6E-20 T 31-10-2018 DFR86_04265 54590de7b61627415e21d4e0692d135b 639 SUPERFAMILY SSF54665 4 100 4.58E-13 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR86_04265 54590de7b61627415e21d4e0692d135b 639 Gene3D G3DSA:3.30.365.10 125 340 1.7E-49 T 31-10-2018 DFR86_04265 54590de7b61627415e21d4e0692d135b 639 Gene3D G3DSA:3.30.365.10 136 228 1.7E-49 T 31-10-2018 DFR86_04265 54590de7b61627415e21d4e0692d135b 639 Gene3D G3DSA:3.90.1170.50 3 100 9.8E-12 T 31-10-2018 DFR86_04265 54590de7b61627415e21d4e0692d135b 639 Gene3D G3DSA:3.30.365.20 487 638 1.4E-20 T 31-10-2018 DFR86_04265 54590de7b61627415e21d4e0692d135b 639 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 106 587 7.3E-86 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR86_04265 54590de7b61627415e21d4e0692d135b 639 SUPERFAMILY SSF56003 92 629 4.32E-100 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR86_04265 54590de7b61627415e21d4e0692d135b 639 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 33 99 2.1E-7 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR86_08470 485cc8d2ba815baabb4780b96e234f36 489 SMART SM00729 203 428 3.9E-21 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_08470 485cc8d2ba815baabb4780b96e234f36 489 Pfam PF04055 Radical SAM superfamily 207 393 6.3E-16 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_08470 485cc8d2ba815baabb4780b96e234f36 489 Gene3D G3DSA:3.80.30.20 203 408 1.1E-22 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe DFR86_08470 485cc8d2ba815baabb4780b96e234f36 489 SUPERFAMILY SSF102114 203 412 7.19E-15 T 31-10-2018 DFR86_03300 e385c28f624257eb2de7ad0f02083343 454 Pfam PF00092 von Willebrand factor type A domain 292 436 6.2E-8 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR86_03300 e385c28f624257eb2de7ad0f02083343 454 SMART SM00327 289 453 5.2E-5 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR86_03300 e385c28f624257eb2de7ad0f02083343 454 Gene3D G3DSA:3.40.50.410 293 453 4.6E-12 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR86_03300 e385c28f624257eb2de7ad0f02083343 454 SUPERFAMILY SSF53300 291 430 8.42E-17 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR86_04395 cad888f497bbe5892cff2b14d8b6c5a3 360 Gene3D G3DSA:3.90.180.10 4 339 3.8E-113 T 31-10-2018 DFR86_04395 cad888f497bbe5892cff2b14d8b6c5a3 360 Gene3D G3DSA:3.40.50.720 143 331 3.8E-113 T 31-10-2018 DFR86_04395 cad888f497bbe5892cff2b14d8b6c5a3 360 SUPERFAMILY SSF50129 1 144 1.52E-33 T 31-10-2018 IPR011032 GroES-like superfamily DFR86_04395 cad888f497bbe5892cff2b14d8b6c5a3 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 136 8.1E-21 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR86_04395 cad888f497bbe5892cff2b14d8b6c5a3 360 Pfam PF16912 Glucose dehydrogenase C-terminus 142 355 1.6E-27 T 31-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 DFR86_04395 cad888f497bbe5892cff2b14d8b6c5a3 360 Hamap MF_02127 Glucose 1-dehydrogenase [gdh]. 1 360 64.731 T 31-10-2018 IPR026583 Glucose 1-dehydrogenase GO:0005536|GO:0008270|GO:0047936 KEGG: 00030+1.1.1.47 DFR86_04395 cad888f497bbe5892cff2b14d8b6c5a3 360 SUPERFAMILY SSF51735 181 311 3.94E-11 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_09055 8374a740ee6a8f81c611b5119fe5a7b7 263 SUPERFAMILY SSF161098 9 254 6.82E-36 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_09055 8374a740ee6a8f81c611b5119fe5a7b7 263 Gene3D G3DSA:1.10.3720.10 6 262 6.7E-41 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_09055 8374a740ee6a8f81c611b5119fe5a7b7 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 261 6.7E-17 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_01280 67126e39d23f3f8a21cc21306134faad 339 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 198 220 2.4E-7 T 31-10-2018 DFR86_01280 67126e39d23f3f8a21cc21306134faad 339 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.4E-7 T 31-10-2018 DFR86_01280 67126e39d23f3f8a21cc21306134faad 339 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 123 141 2.4E-7 T 31-10-2018 DFR86_01280 67126e39d23f3f8a21cc21306134faad 339 SUPERFAMILY SSF51905 3 280 7.45E-22 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_01280 67126e39d23f3f8a21cc21306134faad 339 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 273 4.8E-33 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_01280 67126e39d23f3f8a21cc21306134faad 339 Gene3D G3DSA:3.50.50.100 1 339 8.4E-61 T 31-10-2018 DFR86_05310 ffac59f0bed645ba8a75d37137a93e47 148 SUPERFAMILY SSF49777 5 146 5.36E-44 T 31-10-2018 IPR036610 PEBP-like superfamily DFR86_05310 ffac59f0bed645ba8a75d37137a93e47 148 Pfam PF01161 Phosphatidylethanolamine-binding protein 13 145 3.0E-35 T 31-10-2018 IPR008914 Phosphatidylethanolamine-binding protein DFR86_05310 ffac59f0bed645ba8a75d37137a93e47 148 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 17 143 1.0E-42 T 31-10-2018 IPR005247 YbhB/YbcL DFR86_05310 ffac59f0bed645ba8a75d37137a93e47 148 Gene3D G3DSA:3.90.280.10 1 148 1.2E-51 T 31-10-2018 IPR036610 PEBP-like superfamily DFR86_10060 695a9a2437ce63f5e94fe52592ea822a 506 TIGRFAM TIGR00836 amt: ammonium transporter 65 474 3.4E-111 T 31-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 DFR86_10060 695a9a2437ce63f5e94fe52592ea822a 506 ProSitePatterns PS01219 Ammonium transporters signature. 228 253 - T 31-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 DFR86_10060 695a9a2437ce63f5e94fe52592ea822a 506 Pfam PF00909 Ammonium Transporter Family 67 474 1.6E-92 T 31-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 DFR86_10060 695a9a2437ce63f5e94fe52592ea822a 506 PRINTS PR00342 Rhesus blood group protein signature 386 402 9.6E-5 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 DFR86_10060 695a9a2437ce63f5e94fe52592ea822a 506 PRINTS PR00342 Rhesus blood group protein signature 266 284 9.6E-5 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 DFR86_10060 695a9a2437ce63f5e94fe52592ea822a 506 PRINTS PR00342 Rhesus blood group protein signature 297 319 9.6E-5 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 DFR86_10060 695a9a2437ce63f5e94fe52592ea822a 506 PRINTS PR00342 Rhesus blood group protein signature 172 188 9.6E-5 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 DFR86_10060 695a9a2437ce63f5e94fe52592ea822a 506 SUPERFAMILY SSF111352 60 455 1.12E-102 T 31-10-2018 DFR86_10060 695a9a2437ce63f5e94fe52592ea822a 506 Gene3D G3DSA:1.10.3430.10 40 493 4.9E-122 T 31-10-2018 IPR029020 Ammonium/urea transporter DFR86_03810 69eaaee9d6a0dd4043cb879645cf8061 541 Pfam PF13360 PQQ-like domain 237 410 2.1E-12 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat DFR86_03810 69eaaee9d6a0dd4043cb879645cf8061 541 SMART SM00564 420 452 22.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_03810 69eaaee9d6a0dd4043cb879645cf8061 541 SMART SM00564 311 347 62.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_03810 69eaaee9d6a0dd4043cb879645cf8061 541 SMART SM00564 199 255 41.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_03810 69eaaee9d6a0dd4043cb879645cf8061 541 SMART SM00564 264 297 54.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_03810 69eaaee9d6a0dd4043cb879645cf8061 541 SMART SM00564 156 190 39.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR86_03810 69eaaee9d6a0dd4043cb879645cf8061 541 Gene3D G3DSA:2.40.128.630 419 532 8.1E-10 T 31-10-2018 DFR86_03810 69eaaee9d6a0dd4043cb879645cf8061 541 SUPERFAMILY SSF50998 157 528 2.62E-32 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR86_03810 69eaaee9d6a0dd4043cb879645cf8061 541 Gene3D G3DSA:2.130.10.10 131 418 1.4E-30 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR86_06135 e37600df48e8fedb37dce27560082441 236 PIRSF PIRSF009265 1 231 1.8E-62 T 31-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 DFR86_06135 e37600df48e8fedb37dce27560082441 236 Gene3D G3DSA:3.30.70.270 116 230 1.8E-31 T 31-10-2018 DFR86_06135 e37600df48e8fedb37dce27560082441 236 Gene3D G3DSA:3.30.70.270 8 112 1.1E-6 T 31-10-2018 DFR86_06135 e37600df48e8fedb37dce27560082441 236 Pfam PF05165 GTP cyclohydrolase III 5 224 2.0E-40 T 31-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 DFR86_06135 e37600df48e8fedb37dce27560082441 236 Hamap MF_00608 GTP cyclohydrolase III [gch3]. 3 229 32.021 T 31-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 DFR86_06135 e37600df48e8fedb37dce27560082441 236 ProDom PD313320 GTP III HYDROLASE CYCLOHYDROLASE RIBOFLAVIN BIOSYNTHESIS 3.5.4.- FAMILY MAGNESIUM GGDN 1 225 6.0E-50 T 31-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 DFR86_04585 53da17d96118fb50bee70683a1719ae6 392 Gene3D G3DSA:1.20.1250.20 206 392 2.1E-11 T 31-10-2018 DFR86_04585 53da17d96118fb50bee70683a1719ae6 392 SUPERFAMILY SSF103473 20 390 3.14E-39 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_04585 53da17d96118fb50bee70683a1719ae6 392 Pfam PF07690 Major Facilitator Superfamily 221 388 1.4E-8 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_04585 53da17d96118fb50bee70683a1719ae6 392 Pfam PF07690 Major Facilitator Superfamily 22 189 1.1E-13 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_04585 53da17d96118fb50bee70683a1719ae6 392 Gene3D G3DSA:1.20.1250.20 8 198 2.0E-15 T 31-10-2018 DFR86_00495 5707d07c1e20f5ea8b79111e78c0488e 57 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 40 5.3E-10 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR86_00495 5707d07c1e20f5ea8b79111e78c0488e 57 SUPERFAMILY SSF47598 1 41 1.37E-8 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR86_00495 5707d07c1e20f5ea8b79111e78c0488e 57 Gene3D G3DSA:1.10.1220.10 1 54 7.9E-7 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DFR86_01030 428aa56d20c2bc060cda145d5c0843a2 629 Pfam PF00501 AMP-binding enzyme 93 512 2.5E-69 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR86_01030 428aa56d20c2bc060cda145d5c0843a2 629 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 39 79 2.6E-6 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR86_01030 428aa56d20c2bc060cda145d5c0843a2 629 Pfam PF13193 AMP-binding enzyme C-terminal domain 521 592 5.1E-14 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR86_01030 428aa56d20c2bc060cda145d5c0843a2 629 ProSitePatterns PS00455 Putative AMP-binding domain signature. 264 275 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR86_01030 428aa56d20c2bc060cda145d5c0843a2 629 Gene3D G3DSA:3.30.300.30 509 629 3.3E-20 T 31-10-2018 DFR86_01030 428aa56d20c2bc060cda145d5c0843a2 629 Gene3D G3DSA:3.40.50.12780 68 508 1.8E-76 T 31-10-2018 DFR86_01030 428aa56d20c2bc060cda145d5c0843a2 629 SUPERFAMILY SSF56801 37 624 2.75E-121 T 31-10-2018 DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 SUPERFAMILY SSF55060 179 316 1.48E-26 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 Pfam PF08544 GHMP kinases C terminal 226 297 7.7E-11 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 Pfam PF00288 GHMP kinases N terminal domain 95 162 6.2E-12 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 Gene3D G3DSA:3.30.70.890 181 292 6.4E-72 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 Hamap MF_00217 Mevalonate kinase [mvk]. 2 313 53.07 T 31-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 286 3.2E-74 T 31-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 Gene3D G3DSA:3.30.230.10 7 180 6.4E-72 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 SUPERFAMILY SSF54211 2 170 4.33E-35 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 PRINTS PR00959 Mevalonate kinase family signature 99 121 5.3E-14 T 31-10-2018 DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 PRINTS PR00959 Mevalonate kinase family signature 142 161 5.3E-14 T 31-10-2018 DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 PRINTS PR00959 Mevalonate kinase family signature 6 30 5.3E-14 T 31-10-2018 DFR86_10000 c20777dfc238dee4a97c4851e80b3bb6 319 PRINTS PR00959 Mevalonate kinase family signature 272 289 5.3E-14 T 31-10-2018 DFR86_04035 e9a8d2d41903f05c3c97f36a84738b54 402 Gene3D G3DSA:3.40.50.700 18 277 1.1E-41 T 31-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily DFR86_04035 e9a8d2d41903f05c3c97f36a84738b54 402 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 278 358 4.9E-23 T 31-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal DFR86_04035 e9a8d2d41903f05c3c97f36a84738b54 402 SUPERFAMILY SSF56770 22 360 1.7E-55 T 31-10-2018 DFR86_04035 e9a8d2d41903f05c3c97f36a84738b54 402 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 33 254 3.9E-15 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_04035 e9a8d2d41903f05c3c97f36a84738b54 402 Gene3D G3DSA:4.10.480.10 280 388 1.9E-23 T 31-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily DFR86_04035 e9a8d2d41903f05c3c97f36a84738b54 402 PIRSF PIRSF000310 1 162 1.1E-26 T 31-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DFR86_04035 e9a8d2d41903f05c3c97f36a84738b54 402 PIRSF PIRSF000310 200 402 6.5E-42 T 31-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DFR86_01345 839e5b41520aeedf42b66cf8312242f5 141 SUPERFAMILY SSF54631 6 122 8.72E-33 T 31-10-2018 DFR86_01345 839e5b41520aeedf42b66cf8312242f5 141 Pfam PF00571 CBS domain 9 58 1.5E-10 T 31-10-2018 IPR000644 CBS domain DFR86_01345 839e5b41520aeedf42b66cf8312242f5 141 Pfam PF00571 CBS domain 68 122 3.3E-14 T 31-10-2018 IPR000644 CBS domain DFR86_01345 839e5b41520aeedf42b66cf8312242f5 141 SMART SM00116 76 124 4.8E-12 T 31-10-2018 IPR000644 CBS domain DFR86_01345 839e5b41520aeedf42b66cf8312242f5 141 SMART SM00116 12 59 4.9E-12 T 31-10-2018 IPR000644 CBS domain DFR86_01345 839e5b41520aeedf42b66cf8312242f5 141 Gene3D G3DSA:3.10.580.10 1 135 1.0E-38 T 31-10-2018 DFR86_04950 da8b4871234e52e242527d9ab89930b9 299 Gene3D G3DSA:2.60.120.10 16 286 3.7E-94 T 31-10-2018 IPR014710 RmlC-like jelly roll fold DFR86_04950 da8b4871234e52e242527d9ab89930b9 299 Pfam PF05726 Pirin C-terminal cupin domain 187 290 1.9E-30 T 31-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 DFR86_04950 da8b4871234e52e242527d9ab89930b9 299 SUPERFAMILY SSF51182 1 292 3.17E-85 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily DFR86_04950 da8b4871234e52e242527d9ab89930b9 299 Gene3D G3DSA:2.60.120.10 154 260 3.7E-94 T 31-10-2018 IPR014710 RmlC-like jelly roll fold DFR86_04950 da8b4871234e52e242527d9ab89930b9 299 PIRSF PIRSF006232 1 296 6.5E-95 T 31-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 DFR86_04950 da8b4871234e52e242527d9ab89930b9 299 Pfam PF02678 Pirin 20 132 2.4E-38 T 31-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 DFR86_05450 590be69654080cf1bed886def8d89be0 350 PIRSF PIRSF004930 1 340 4.9E-128 T 31-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 DFR86_05450 590be69654080cf1bed886def8d89be0 350 Gene3D G3DSA:3.90.870.10 1 214 5.5E-86 T 31-10-2018 DFR86_05450 590be69654080cf1bed886def8d89be0 350 Pfam PF03481 Putative GTP-binding controlling metal-binding 222 334 1.4E-22 T 31-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain DFR86_05450 590be69654080cf1bed886def8d89be0 350 SUPERFAMILY SSF55821 5 211 2.66E-67 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily DFR86_05450 590be69654080cf1bed886def8d89be0 350 Pfam PF01300 Telomere recombination 23 198 2.9E-56 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 DFR86_05450 590be69654080cf1bed886def8d89be0 350 Gene3D G3DSA:3.40.50.11030 219 350 4.3E-43 T 31-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily DFR86_05450 590be69654080cf1bed886def8d89be0 350 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 208 7.9E-66 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 SMART SM01097 6 143 2.1E-76 T 31-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 9 367 3.5E-120 T 31-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 Gene3D G3DSA:3.40.50.880 172 370 4.8E-30 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 8 142 2.1E-46 T 31-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 SUPERFAMILY SSF52021 7 152 1.7E-49 T 31-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 Gene3D G3DSA:3.50.30.20 5 159 4.4E-54 T 31-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 297 308 5.2E-27 T 31-10-2018 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 272 289 5.2E-27 T 31-10-2018 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 255 271 5.2E-27 T 31-10-2018 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 185 199 5.2E-27 T 31-10-2018 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 224 238 5.2E-27 T 31-10-2018 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 PRINTS PR00096 Glutamine amidotransferase superfamily signature 341 354 8.9E-9 T 31-10-2018 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 PRINTS PR00096 Glutamine amidotransferase superfamily signature 255 266 8.9E-9 T 31-10-2018 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 PRINTS PR00096 Glutamine amidotransferase superfamily signature 227 236 8.9E-9 T 31-10-2018 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 6 370 41.948 T 31-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 Pfam PF00117 Glutamine amidotransferase class-I 187 364 3.5E-42 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR86_08290 bfe05387928f0e83c53b6d73e8ead4b4 371 SUPERFAMILY SSF52317 154 368 1.16E-51 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR86_03130 341848bae9c29c1afc1a72fa7565557e 244 Gene3D G3DSA:3.40.50.300 2 243 8.3E-64 T 31-10-2018 DFR86_03130 341848bae9c29c1afc1a72fa7565557e 244 SMART SM00382 32 211 1.4E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_03130 341848bae9c29c1afc1a72fa7565557e 244 SUPERFAMILY SSF52540 7 227 3.48E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03130 341848bae9c29c1afc1a72fa7565557e 244 Pfam PF00005 ABC transporter 23 165 1.5E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_01610 22bbe87980ef96faf7c52498edfbdbf8 255 SUPERFAMILY SSF56281 17 218 1.57E-37 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_01610 22bbe87980ef96faf7c52498edfbdbf8 255 Pfam PF00753 Metallo-beta-lactamase superfamily 21 201 4.4E-22 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_01610 22bbe87980ef96faf7c52498edfbdbf8 255 Gene3D G3DSA:3.60.15.10 1 254 3.8E-70 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_01610 22bbe87980ef96faf7c52498edfbdbf8 255 SMART SM00849 19 201 2.2E-28 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_05210 1cb184f54e9071410f06f72e70c1c6ca 495 Pfam PF13175 AAA ATPase domain 9 113 6.8E-8 T 31-10-2018 DFR86_05210 1cb184f54e9071410f06f72e70c1c6ca 495 Pfam PF13175 AAA ATPase domain 172 285 1.4E-18 T 31-10-2018 DFR86_05210 1cb184f54e9071410f06f72e70c1c6ca 495 SUPERFAMILY SSF52540 3 300 7.47E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_05210 1cb184f54e9071410f06f72e70c1c6ca 495 Gene3D G3DSA:3.40.50.300 2 316 1.3E-25 T 31-10-2018 DFR86_08510 f89532d3b62494b760ed780127800b6c 195 Gene3D G3DSA:3.30.230.40 93 195 3.1E-34 T 31-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 DFR86_08510 f89532d3b62494b760ed780127800b6c 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 159 171 - T 31-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 DFR86_08510 f89532d3b62494b760ed780127800b6c 195 Gene3D G3DSA:3.30.230.40 2 92 4.1E-31 T 31-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 DFR86_08510 f89532d3b62494b760ed780127800b6c 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 64 77 - T 31-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 DFR86_08510 f89532d3b62494b760ed780127800b6c 195 SUPERFAMILY SSF54211 5 89 2.02E-27 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_08510 f89532d3b62494b760ed780127800b6c 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 5 195 36.818 T 31-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 DFR86_08510 f89532d3b62494b760ed780127800b6c 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 34 177 1.4E-54 T 31-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 DFR86_08510 f89532d3b62494b760ed780127800b6c 195 SUPERFAMILY SSF54211 90 182 9.61E-31 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_04225 5f7c598a982c72dfb6348839e5f4fc21 495 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 28 459 1.1E-63 T 31-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 DFR86_04225 5f7c598a982c72dfb6348839e5f4fc21 495 Gene3D G3DSA:1.10.4160.10 13 484 2.7E-77 T 31-10-2018 IPR038271 Purine-cytosine permease superfamily DFR86_00880 e878ea674d4f12a6f38788178ae16980 186 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 10 174 1.0E-49 T 31-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DFR86_00880 e878ea674d4f12a6f38788178ae16980 186 SUPERFAMILY SSF51182 6 181 1.35E-64 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily DFR86_00880 e878ea674d4f12a6f38788178ae16980 186 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 9 174 1.3E-62 T 31-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DFR86_00880 e878ea674d4f12a6f38788178ae16980 186 Gene3D G3DSA:2.60.120.10 5 182 3.1E-67 T 31-10-2018 IPR014710 RmlC-like jelly roll fold DFR86_00880 e878ea674d4f12a6f38788178ae16980 186 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 6 175 3.1E-64 T 31-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DFR86_10890 d3d852f06472a2c430d107ded61cae51 213 Gene3D G3DSA:1.10.620.20 4 212 3.3E-23 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR86_10890 d3d852f06472a2c430d107ded61cae51 213 SUPERFAMILY SSF47240 8 207 4.33E-16 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR86_10770 0d60313c0c2883eee6d13324f7f94d1b 365 SUPERFAMILY SSF51905 5 345 1.2E-23 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_10770 0d60313c0c2883eee6d13324f7f94d1b 365 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 7.4E-18 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_10770 0d60313c0c2883eee6d13324f7f94d1b 365 Gene3D G3DSA:3.50.50.60 3 156 5.0E-15 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_10770 0d60313c0c2883eee6d13324f7f94d1b 365 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 6.5E-6 T 31-10-2018 DFR86_10770 0d60313c0c2883eee6d13324f7f94d1b 365 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 6.5E-6 T 31-10-2018 DFR86_10770 0d60313c0c2883eee6d13324f7f94d1b 365 Gene3D G3DSA:3.50.50.60 204 347 3.3E-6 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_06230 7813b1fc3cfb44c071fb41c406dd37eb 105 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 8 98 5.2E-17 T 31-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 DFR86_06230 7813b1fc3cfb44c071fb41c406dd37eb 105 SUPERFAMILY SSF55315 5 99 3.24E-25 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR86_06230 7813b1fc3cfb44c071fb41c406dd37eb 105 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 17 41 - T 31-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06230 7813b1fc3cfb44c071fb41c406dd37eb 105 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 5 102 27.541 T 31-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06230 7813b1fc3cfb44c071fb41c406dd37eb 105 Gene3D G3DSA:3.30.1330.30 4 102 5.1E-33 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR86_02435 4047132828b0dedcde3000bc742c3b14 394 Pfam PF01425 Amidase 285 381 4.8E-16 T 31-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR86_02435 4047132828b0dedcde3000bc742c3b14 394 Pfam PF01425 Amidase 20 189 5.4E-64 T 31-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR86_02435 4047132828b0dedcde3000bc742c3b14 394 ProSitePatterns PS00571 Amidases signature. 108 139 - T 31-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 DFR86_02435 4047132828b0dedcde3000bc742c3b14 394 SUPERFAMILY SSF75304 4 387 1.31E-104 T 31-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR86_02435 4047132828b0dedcde3000bc742c3b14 394 Gene3D G3DSA:3.90.1300.10 2 392 6.3E-105 T 31-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR86_08360 2051ef280bff5f352e7a69c1cb92d60e 330 SUPERFAMILY SSF52540 160 329 4.21E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08360 2051ef280bff5f352e7a69c1cb92d60e 330 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 2.1E-11 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_08360 2051ef280bff5f352e7a69c1cb92d60e 330 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 224 2.1E-11 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_08360 2051ef280bff5f352e7a69c1cb92d60e 330 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 2.1E-11 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_08360 2051ef280bff5f352e7a69c1cb92d60e 330 Gene3D G3DSA:3.40.50.300 152 329 3.6E-46 T 31-10-2018 DFR86_08360 2051ef280bff5f352e7a69c1cb92d60e 330 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 318 1.3E-17 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 DFR86_08360 2051ef280bff5f352e7a69c1cb92d60e 330 Pfam PF01926 50S ribosome-binding GTPase 161 278 1.7E-20 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_08360 2051ef280bff5f352e7a69c1cb92d60e 330 Gene3D G3DSA:1.20.120.1190 2 151 1.5E-19 T 31-10-2018 DFR86_00725 6b961e8ed4e41da0d89166ccd8f863f4 405 Pfam PF13173 AAA domain 38 161 1.2E-27 T 31-10-2018 DFR86_00725 6b961e8ed4e41da0d89166ccd8f863f4 405 SUPERFAMILY SSF52540 38 212 8.42E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00725 6b961e8ed4e41da0d89166ccd8f863f4 405 Pfam PF13635 Domain of unknown function (DUF4143) 234 342 1.4E-8 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 DFR86_10610 215bab61275a1c2e9bde7b8195f0b971 137 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 14 125 1.1E-19 T 31-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 DFR86_10610 215bab61275a1c2e9bde7b8195f0b971 137 Gene3D G3DSA:3.10.129.10 3 137 3.9E-31 T 31-10-2018 DFR86_10610 215bab61275a1c2e9bde7b8195f0b971 137 SUPERFAMILY SSF54637 9 133 1.29E-27 T 31-10-2018 IPR029069 HotDog domain superfamily DFR86_10610 215bab61275a1c2e9bde7b8195f0b971 137 Pfam PF03061 Thioesterase superfamily 44 119 6.4E-15 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR86_04415 b02ded23b5753383540bc066ca8b6153 283 Gene3D G3DSA:2.120.10.30 1 281 1.3E-89 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like DFR86_04415 b02ded23b5753383540bc066ca8b6153 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 89 110 3.4E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_04415 b02ded23b5753383540bc066ca8b6153 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 130 152 3.4E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_04415 b02ded23b5753383540bc066ca8b6153 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 13 30 3.4E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_04415 b02ded23b5753383540bc066ca8b6153 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 153 173 3.4E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_04415 b02ded23b5753383540bc066ca8b6153 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 193 210 3.4E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_04415 b02ded23b5753383540bc066ca8b6153 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 235 253 3.4E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_04415 b02ded23b5753383540bc066ca8b6153 283 SUPERFAMILY SSF63829 9 279 4.58E-63 T 31-10-2018 DFR86_04415 b02ded23b5753383540bc066ca8b6153 283 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 12 253 6.5E-75 T 31-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region DFR86_08085 57676ccbc37339e589504c5e7a1f22fc 177 Pfam PF01435 Peptidase family M48 40 177 6.4E-18 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DFR86_08215 1a31ee3270b4ed929da80cd27818b186 312 SUPERFAMILY SSF55347 143 293 1.18E-43 T 31-10-2018 DFR86_08215 1a31ee3270b4ed929da80cd27818b186 312 PIRSF PIRSF036497 1 312 8.1E-88 T 31-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 DFR86_08215 1a31ee3270b4ed929da80cd27818b186 312 Pfam PF00742 Homoserine dehydrogenase 141 306 2.8E-49 T 31-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 DFR86_08215 1a31ee3270b4ed929da80cd27818b186 312 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 179 201 - T 31-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 DFR86_08215 1a31ee3270b4ed929da80cd27818b186 312 Gene3D G3DSA:3.40.50.720 5 306 9.5E-97 T 31-10-2018 DFR86_08215 1a31ee3270b4ed929da80cd27818b186 312 Gene3D G3DSA:3.30.360.10 145 289 9.5E-97 T 31-10-2018 DFR86_08215 1a31ee3270b4ed929da80cd27818b186 312 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 7 126 5.2E-9 T 31-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 DFR86_08215 1a31ee3270b4ed929da80cd27818b186 312 SUPERFAMILY SSF51735 1 155 2.19E-22 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_09985 3f1ce146c59e67cb3df6054fd3014f4f 244 Pfam PF00535 Glycosyl transferase family 2 3 131 4.5E-24 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_09985 3f1ce146c59e67cb3df6054fd3014f4f 244 Gene3D G3DSA:3.90.550.10 1 235 6.1E-34 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_09985 3f1ce146c59e67cb3df6054fd3014f4f 244 SUPERFAMILY SSF53448 1 222 4.73E-33 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_07850 e5270c7e0103a0482b23b413cab9de72 211 Gene3D G3DSA:3.40.50.11330 89 211 1.2E-22 T 31-10-2018 DFR86_07850 e5270c7e0103a0482b23b413cab9de72 211 Gene3D G3DSA:3.40.50.1860 1 87 6.2E-5 T 31-10-2018 DFR86_02010 702c0255bf54291a8bf00bcee14070e7 178 SUPERFAMILY SSF53218 12 173 3.53E-39 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR86_02010 702c0255bf54291a8bf00bcee14070e7 178 PIRSF PIRSF006443 1 178 1.6E-57 T 31-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 DFR86_02010 702c0255bf54291a8bf00bcee14070e7 178 SMART SM00852 18 171 2.5E-25 T 31-10-2018 IPR001453 MoaB/Mog domain DFR86_02010 702c0255bf54291a8bf00bcee14070e7 178 Pfam PF00994 Probable molybdopterin binding domain 19 170 1.4E-31 T 31-10-2018 IPR001453 MoaB/Mog domain DFR86_02010 702c0255bf54291a8bf00bcee14070e7 178 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 16 166 1.2E-32 T 31-10-2018 IPR001453 MoaB/Mog domain DFR86_02010 702c0255bf54291a8bf00bcee14070e7 178 Gene3D G3DSA:3.40.980.10 2 176 4.6E-44 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR86_02550 b2e368b5519a9ab539b00c2940d7efcb 138 SUPERFAMILY SSF52833 5 137 1.39E-41 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_02550 b2e368b5519a9ab539b00c2940d7efcb 138 TIGRFAM TIGR01068 thioredoxin: thioredoxin 41 135 5.3E-34 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DFR86_02550 b2e368b5519a9ab539b00c2940d7efcb 138 PIRSF PIRSF000077 33 137 9.5E-32 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DFR86_02550 b2e368b5519a9ab539b00c2940d7efcb 138 Pfam PF00085 Thioredoxin 36 135 1.8E-27 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 DFR86_02550 b2e368b5519a9ab539b00c2940d7efcb 138 PRINTS PR00421 Thioredoxin family signature 62 71 5.4E-7 T 31-10-2018 DFR86_02550 b2e368b5519a9ab539b00c2940d7efcb 138 PRINTS PR00421 Thioredoxin family signature 101 112 5.4E-7 T 31-10-2018 DFR86_02550 b2e368b5519a9ab539b00c2940d7efcb 138 PRINTS PR00421 Thioredoxin family signature 54 62 5.4E-7 T 31-10-2018 DFR86_02550 b2e368b5519a9ab539b00c2940d7efcb 138 Gene3D G3DSA:3.40.30.10 7 138 3.9E-36 T 31-10-2018 DFR86_03245 09c88506bdfce948517ed0cdea26058a 178 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 3 166 3.4E-55 T 31-10-2018 IPR019964 KH domain protein, archaea DFR86_03245 09c88506bdfce948517ed0cdea26058a 178 Gene3D G3DSA:3.30.1370.10 73 175 1.5E-33 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 DFR86_03245 09c88506bdfce948517ed0cdea26058a 178 Gene3D G3DSA:3.30.1370.10 2 72 1.6E-6 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 DFR86_03245 09c88506bdfce948517ed0cdea26058a 178 SUPERFAMILY SSF54791 74 159 2.78E-18 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 DFR86_10970 966256e6e3a136a9dcdb380e41e6550b 378 SUPERFAMILY SSF103473 10 373 1.83E-16 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_10970 966256e6e3a136a9dcdb380e41e6550b 378 Gene3D G3DSA:1.20.1250.20 42 370 6.9E-11 T 31-10-2018 DFR86_10970 966256e6e3a136a9dcdb380e41e6550b 378 Pfam PF07690 Major Facilitator Superfamily 42 326 6.3E-9 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_09090 75a6da18ec2ece4a121a79de25b10e51 257 SUPERFAMILY SSF56281 15 244 2.1E-35 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_09090 75a6da18ec2ece4a121a79de25b10e51 257 Gene3D G3DSA:3.60.15.10 3 248 8.7E-49 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_09090 75a6da18ec2ece4a121a79de25b10e51 257 SMART SM00849 36 227 2.1E-20 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_09090 75a6da18ec2ece4a121a79de25b10e51 257 Pfam PF00753 Metallo-beta-lactamase superfamily 37 227 7.5E-15 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_08905 c05db436599926e91da2765959697665 331 Pfam PF01866 Putative diphthamide synthesis protein 26 322 1.5E-76 T 31-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR86_08905 c05db436599926e91da2765959697665 331 Gene3D G3DSA:3.40.50.11860 216 320 6.7E-29 T 31-10-2018 DFR86_08905 c05db436599926e91da2765959697665 331 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 18 328 2.0E-94 T 31-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 DFR86_08905 c05db436599926e91da2765959697665 331 Gene3D G3DSA:3.40.50.11840 6 102 4.3E-29 T 31-10-2018 DFR86_08905 c05db436599926e91da2765959697665 331 Gene3D G3DSA:3.40.50.11850 106 210 3.6E-25 T 31-10-2018 DFR86_08905 c05db436599926e91da2765959697665 331 PIRSF PIRSF004967 1 331 6.1E-90 T 31-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR86_08905 c05db436599926e91da2765959697665 331 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 3 319 4.6E-93 T 31-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR86_10760 f5279e64b4a88f621b7a5ff70fec03a1 278 SUPERFAMILY SSF46548 50 139 4.88E-15 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_10760 f5279e64b4a88f621b7a5ff70fec03a1 278 Pfam PF13237 4Fe-4S dicluster domain 63 121 5.8E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_10760 f5279e64b4a88f621b7a5ff70fec03a1 278 Gene3D G3DSA:1.10.1060.10 37 142 1.7E-9 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR86_10760 f5279e64b4a88f621b7a5ff70fec03a1 278 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_10760 f5279e64b4a88f621b7a5ff70fec03a1 278 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_10895 7f891dc20d4e1ca278f4366a3f95ee56 200 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 7 194 1.0E-44 T 31-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 DFR86_10895 7f891dc20d4e1ca278f4366a3f95ee56 200 Pfam PF03358 NADPH-dependent FMN reductase 19 144 6.0E-16 T 31-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 DFR86_10895 7f891dc20d4e1ca278f4366a3f95ee56 200 Gene3D G3DSA:3.40.50.360 1 199 1.5E-67 T 31-10-2018 IPR029039 Flavoprotein-like superfamily DFR86_10895 7f891dc20d4e1ca278f4366a3f95ee56 200 SUPERFAMILY SSF52218 6 195 5.28E-49 T 31-10-2018 IPR029039 Flavoprotein-like superfamily DFR86_08725 2b28dfcfe6d645ca9bb442aa7d709722 1151 Pfam PF00361 Proton-conducting membrane transporter 121 421 4.0E-47 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08725 2b28dfcfe6d645ca9bb442aa7d709722 1151 Pfam PF00361 Proton-conducting membrane transporter 623 950 3.7E-26 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08725 2b28dfcfe6d645ca9bb442aa7d709722 1151 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 157 181 3.3E-14 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08725 2b28dfcfe6d645ca9bb442aa7d709722 1151 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 327 346 3.3E-14 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08725 2b28dfcfe6d645ca9bb442aa7d709722 1151 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 127 146 3.3E-14 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08725 2b28dfcfe6d645ca9bb442aa7d709722 1151 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 379 405 3.3E-14 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08725 2b28dfcfe6d645ca9bb442aa7d709722 1151 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 566 609 2.1E-6 T 31-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_03800 04b44b9d55d514f85d554cbea93df4c5 304 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 46 195 8.7E-26 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR86_03800 04b44b9d55d514f85d554cbea93df4c5 304 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 12 300 3.5E-125 T 31-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate DFR86_03800 04b44b9d55d514f85d554cbea93df4c5 304 Gene3D G3DSA:3.40.50.970 28 197 2.9E-18 T 31-10-2018 DFR86_03800 04b44b9d55d514f85d554cbea93df4c5 304 SUPERFAMILY SSF52518 11 263 9.38E-69 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_03800 04b44b9d55d514f85d554cbea93df4c5 304 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 270 1.4E-21 T 31-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal DFR86_11190 ca97929d5895e2d7189c8f5658c39db9 226 SMART SM00849 24 220 2.0E-23 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_11190 ca97929d5895e2d7189c8f5658c39db9 226 SUPERFAMILY SSF56281 6 222 3.93E-35 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_11190 ca97929d5895e2d7189c8f5658c39db9 226 Gene3D G3DSA:3.60.15.10 4 225 2.2E-37 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_11190 ca97929d5895e2d7189c8f5658c39db9 226 Pfam PF00753 Metallo-beta-lactamase superfamily 23 220 7.3E-26 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_06625 fd1fad0b8ee2a7a81539d2ffd39e34cd 113 PIRSF PIRSF005053 1 111 1.4E-29 T 31-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) DFR86_06625 fd1fad0b8ee2a7a81539d2ffd39e34cd 113 Gene3D G3DSA:1.10.150.820 49 87 1.5E-14 T 31-10-2018 DFR86_06625 fd1fad0b8ee2a7a81539d2ffd39e34cd 113 Pfam PF03874 RNA polymerase Rpb4 28 109 1.3E-6 T 31-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 DFR86_06625 fd1fad0b8ee2a7a81539d2ffd39e34cd 113 SUPERFAMILY SSF47819 5 106 3.66E-23 T 31-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 DFR86_02900 8a3237ea6ffef3bab6fcebd4c31eef33 153 Pfam PF00293 NUDIX domain 4 112 4.4E-18 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 DFR86_02900 8a3237ea6ffef3bab6fcebd4c31eef33 153 SUPERFAMILY SSF55811 5 136 1.12E-29 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 DFR86_02900 8a3237ea6ffef3bab6fcebd4c31eef33 153 Gene3D G3DSA:3.90.79.10 3 138 2.2E-31 T 31-10-2018 DFR86_09720 cc7fe29d2f1f4fdfa288a5aef9f1b0cf 138 Pfam PF01886 Protein of unknown function DUF61 3 120 1.2E-22 T 31-10-2018 IPR002746 Uncharacterised protein family UPF0216 DFR86_02135 6d7edd775453adc994c432aa980cd927 256 SUPERFAMILY SSF52096 3 251 1.49E-47 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR86_02135 6d7edd775453adc994c432aa980cd927 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 248 2.0E-36 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR86_02135 6d7edd775453adc994c432aa980cd927 256 Gene3D G3DSA:3.90.226.10 2 248 6.0E-49 T 31-10-2018 DFR86_03285 8926f9928da309e418ece739c7b87e45 93 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 32 91 2.1E-13 T 31-10-2018 IPR008792 Coenzyme PQQ synthesis D DFR86_03285 8926f9928da309e418ece739c7b87e45 93 Gene3D G3DSA:1.10.10.1150 17 93 7.6E-6 T 31-10-2018 DFR86_01035 c51a1412b9415e7784fecabee27baad9 154 SUPERFAMILY SSF50249 15 145 1.56E-20 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_01035 c51a1412b9415e7784fecabee27baad9 154 Gene3D G3DSA:2.40.50.140 76 154 2.1E-22 T 31-10-2018 DFR86_01035 c51a1412b9415e7784fecabee27baad9 154 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 37 69 1.6E-7 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DFR86_01035 c51a1412b9415e7784fecabee27baad9 154 Gene3D G3DSA:1.10.12.20 1 75 8.5E-31 T 31-10-2018 DFR86_02975 aec0801e1cbccee31d2c3268fa760276 45 SUPERFAMILY SSF47240 5 42 4.33E-8 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR86_02975 aec0801e1cbccee31d2c3268fa760276 45 SMART SM00746 3 39 1.6E-8 T 31-10-2018 IPR011017 TRASH domain DFR86_02975 aec0801e1cbccee31d2c3268fa760276 45 Pfam PF04945 YHS domain 1 43 2.2E-16 T 31-10-2018 IPR007029 YHS domain DFR86_02975 aec0801e1cbccee31d2c3268fa760276 45 Gene3D G3DSA:1.10.620.20 1 45 9.0E-10 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR86_06285 68fdfc266b857b59077787b7a7d8ebce 134 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 10 132 1.9E-47 T 31-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 DFR86_06285 68fdfc266b857b59077787b7a7d8ebce 134 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 98 - T 31-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 DFR86_06285 68fdfc266b857b59077787b7a7d8ebce 134 SUPERFAMILY SSF53927 6 130 3.18E-44 T 31-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 DFR86_06285 68fdfc266b857b59077787b7a7d8ebce 134 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 102 5.1E-19 T 31-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain DFR86_06285 68fdfc266b857b59077787b7a7d8ebce 134 Gene3D G3DSA:3.40.140.10 3 133 1.8E-50 T 31-10-2018 DFR86_10015 db4ccb66d073c97bb2e366a4406d1991 115 Gene3D G3DSA:1.10.8.10 72 111 8.1E-15 T 31-10-2018 DFR86_10015 db4ccb66d073c97bb2e366a4406d1991 115 SMART SM01407 5 63 2.6E-8 T 31-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain DFR86_10015 db4ccb66d073c97bb2e366a4406d1991 115 Gene3D G3DSA:2.20.70.30 9 68 1.4E-8 T 31-10-2018 IPR038187 NAC A/B domain superfamily DFR86_10015 db4ccb66d073c97bb2e366a4406d1991 115 SUPERFAMILY SSF46934 59 112 4.38E-9 T 31-10-2018 IPR009060 UBA-like superfamily GO:0005515 DFR86_09250 aba2542d73dab329e1c92fa84a2ce8c4 168 SMART SM00649 6 138 2.3E-51 T 31-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 DFR86_09250 aba2542d73dab329e1c92fa84a2ce8c4 168 Gene3D G3DSA:2.10.260.30 3 69 1.4E-23 T 31-10-2018 DFR86_09250 aba2542d73dab329e1c92fa84a2ce8c4 168 Pfam PF03946 Ribosomal protein L11, N-terminal domain 6 61 1.0E-17 T 31-10-2018 IPR020784 Ribosomal protein L11, N-terminal DFR86_09250 aba2542d73dab329e1c92fa84a2ce8c4 168 SUPERFAMILY SSF46906 66 137 1.1E-17 T 31-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily DFR86_09250 aba2542d73dab329e1c92fa84a2ce8c4 168 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 2 139 23.382 T 31-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 DFR86_09250 aba2542d73dab329e1c92fa84a2ce8c4 168 SUPERFAMILY SSF54747 3 81 2.75E-21 T 31-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily DFR86_09250 aba2542d73dab329e1c92fa84a2ce8c4 168 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 137 7.1E-18 T 31-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 DFR86_09250 aba2542d73dab329e1c92fa84a2ce8c4 168 Gene3D G3DSA:1.10.10.250 73 163 5.4E-27 T 31-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily DFR86_08880 ecae11acce7826cb2c7572f5fa1ac255 342 Gene3D G3DSA:3.40.50.720 48 284 1.2E-68 T 31-10-2018 DFR86_08880 ecae11acce7826cb2c7572f5fa1ac255 342 Pfam PF00899 ThiF family 55 281 3.4E-55 T 31-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 DFR86_08880 ecae11acce7826cb2c7572f5fa1ac255 342 SUPERFAMILY SSF69572 47 302 1.44E-77 T 31-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 DFR86_02505 67994d20f2d12968f82e975271ccc5a4 134 Gene3D G3DSA:1.10.10.10 3 82 2.1E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_02505 67994d20f2d12968f82e975271ccc5a4 134 Pfam PF01475 Ferric uptake regulator family 11 124 1.3E-23 T 31-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 DFR86_02505 67994d20f2d12968f82e975271ccc5a4 134 SUPERFAMILY SSF46785 6 129 1.44E-28 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_06875 0c7782d55ea7dd89fc14325ae8b362b6 156 Gene3D G3DSA:3.30.1390.20 7 144 2.0E-37 T 31-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily DFR86_06875 0c7782d55ea7dd89fc14325ae8b362b6 156 SUPERFAMILY SSF55129 6 156 3.01E-36 T 31-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily DFR86_06875 0c7782d55ea7dd89fc14325ae8b362b6 156 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 7 156 9.9E-45 T 31-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 DFR86_06875 0c7782d55ea7dd89fc14325ae8b362b6 156 Pfam PF00327 Ribosomal protein L30p/L7e 5 55 1.0E-14 T 31-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain DFR86_06875 0c7782d55ea7dd89fc14325ae8b362b6 156 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 156 52.441 T 31-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 DFR86_06875 0c7782d55ea7dd89fc14325ae8b362b6 156 Gene3D G3DSA:1.10.15.30 61 115 2.0E-37 T 31-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type DFR86_02575 132ba70c34a2057852b1af1db55cf4f0 326 Pfam PF01545 Cation efflux family 18 195 1.8E-13 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DFR86_02575 132ba70c34a2057852b1af1db55cf4f0 326 Gene3D G3DSA:1.20.1510.10 10 196 4.8E-8 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily DFR86_02575 132ba70c34a2057852b1af1db55cf4f0 326 SUPERFAMILY SSF161111 9 197 6.15E-14 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily DFR86_07020 75ba3706879a11844c4b5e98a2ed9c40 105 Gene3D G3DSA:1.10.10.10 5 97 7.9E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_07020 75ba3706879a11844c4b5e98a2ed9c40 105 SUPERFAMILY SSF46785 7 89 1.68E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_07020 75ba3706879a11844c4b5e98a2ed9c40 105 Pfam PF01022 Bacterial regulatory protein, arsR family 22 65 5.8E-8 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR86_01600 b809523d4b50fafd0106bb67b16f4b4a 785 Pfam PF00069 Protein kinase domain 466 772 2.1E-27 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR86_01600 b809523d4b50fafd0106bb67b16f4b4a 785 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 610 622 - T 31-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DFR86_01600 b809523d4b50fafd0106bb67b16f4b4a 785 SUPERFAMILY SSF56112 463 782 2.08E-38 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR86_01600 b809523d4b50fafd0106bb67b16f4b4a 785 Gene3D G3DSA:1.10.510.10 557 782 5.1E-26 T 31-10-2018 DFR86_01600 b809523d4b50fafd0106bb67b16f4b4a 785 SMART SM00220 466 780 6.9E-16 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR86_01600 b809523d4b50fafd0106bb67b16f4b4a 785 Gene3D G3DSA:3.30.200.20 457 546 2.2E-5 T 31-10-2018 DFR86_01600 b809523d4b50fafd0106bb67b16f4b4a 785 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 472 493 - T 31-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 DFR86_11330 2d4e713a1bf7f83ec42b683c0f16e419 159 Gene3D G3DSA:3.10.580.10 24 158 5.7E-34 T 31-10-2018 DFR86_11330 2d4e713a1bf7f83ec42b683c0f16e419 159 Pfam PF00571 CBS domain 33 87 1.7E-14 T 31-10-2018 IPR000644 CBS domain DFR86_11330 2d4e713a1bf7f83ec42b683c0f16e419 159 Pfam PF00571 CBS domain 96 148 3.0E-9 T 31-10-2018 IPR000644 CBS domain DFR86_11330 2d4e713a1bf7f83ec42b683c0f16e419 159 SUPERFAMILY SSF54631 30 148 2.27E-30 T 31-10-2018 DFR86_11330 2d4e713a1bf7f83ec42b683c0f16e419 159 SMART SM00116 103 150 4.5E-6 T 31-10-2018 IPR000644 CBS domain DFR86_11330 2d4e713a1bf7f83ec42b683c0f16e419 159 SMART SM00116 40 87 1.2E-7 T 31-10-2018 IPR000644 CBS domain DFR86_11680 2bbe34bc42b9ee53ef9b7e1bfaa8f18b 478 SUPERFAMILY SSF53300 320 427 2.7E-5 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR86_05370 aca7577bab5f4948d8f3fd5f2a1f8f52 186 SMART SM00382 17 161 7.8E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_05370 aca7577bab5f4948d8f3fd5f2a1f8f52 186 Gene3D G3DSA:3.40.50.300 11 183 2.8E-14 T 31-10-2018 DFR86_05370 aca7577bab5f4948d8f3fd5f2a1f8f52 186 SUPERFAMILY SSF52540 16 173 1.56E-14 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01150 0cffb17bc851ae746267117eb1e7657f 380 SUPERFAMILY SSF53649 34 377 9.35E-34 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 DFR86_01150 0cffb17bc851ae746267117eb1e7657f 380 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 38 291 6.5E-18 T 31-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 DFR86_01150 0cffb17bc851ae746267117eb1e7657f 380 Gene3D G3DSA:3.40.720.10 25 376 4.2E-28 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR86_06005 c6d1eff8ddfbe685f44c0ba11d603491 258 PIRSF PIRSF017269 1 257 1.2E-83 T 31-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 DFR86_06005 c6d1eff8ddfbe685f44c0ba11d603491 258 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 59 237 1.4E-32 T 31-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 DFR86_06005 c6d1eff8ddfbe685f44c0ba11d603491 258 Gene3D G3DSA:3.10.330.20 1 62 1.0E-15 T 31-10-2018 DFR86_06005 c6d1eff8ddfbe685f44c0ba11d603491 258 Gene3D G3DSA:3.40.50.150 65 256 6.8E-64 T 31-10-2018 DFR86_06005 c6d1eff8ddfbe685f44c0ba11d603491 258 SUPERFAMILY SSF53335 2 251 1.89E-67 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_09255 91d68861c6240f566fb321e61eac6eed 218 SUPERFAMILY SSF56808 2 215 3.53E-53 T 31-10-2018 IPR023674 Ribosomal protein L1-like DFR86_09255 91d68861c6240f566fb321e61eac6eed 218 Gene3D G3DSA:3.40.50.790 62 152 2.4E-60 T 31-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich DFR86_09255 91d68861c6240f566fb321e61eac6eed 218 PIRSF PIRSF002155 1 218 5.8E-56 T 31-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09255 91d68861c6240f566fb321e61eac6eed 218 ProSitePatterns PS01199 Ribosomal protein L1 signature. 117 136 - T 31-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_09255 91d68861c6240f566fb321e61eac6eed 218 Gene3D G3DSA:3.30.190.20 21 211 2.4E-60 T 31-10-2018 DFR86_09255 91d68861c6240f566fb321e61eac6eed 218 Pfam PF00687 Ribosomal protein L1p/L10e family 23 210 7.0E-33 T 31-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein DFR86_09255 91d68861c6240f566fb321e61eac6eed 218 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 216 31.413 T 31-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 DFR86_09945 52de40ea2b4033a44d2116cfb35a3bd0 109 Pfam PF16239 Domain of unknown function (DUF4898) 37 104 1.2E-9 T 31-10-2018 IPR032603 Protein of unknown function DUF4898 DFR86_00670 46ea15c8b281a4b7f84b3d3d3aedc6c5 413 Pfam PF13641 Glycosyltransferase like family 2 56 276 3.0E-22 T 31-10-2018 DFR86_00670 46ea15c8b281a4b7f84b3d3d3aedc6c5 413 SUPERFAMILY SSF53448 51 311 2.17E-39 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00670 46ea15c8b281a4b7f84b3d3d3aedc6c5 413 Gene3D G3DSA:3.90.550.10 38 263 2.2E-26 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00950 c02b942d34191748afa71cdbb4a4ee8a 346 Gene3D G3DSA:3.40.50.150 146 345 1.7E-26 T 31-10-2018 DFR86_00950 c02b942d34191748afa71cdbb4a4ee8a 346 Pfam PF05050 Methyltransferase FkbM domain 165 323 3.5E-12 T 31-10-2018 IPR006342 Methyltransferase FkbM DFR86_00950 c02b942d34191748afa71cdbb4a4ee8a 346 SUPERFAMILY SSF53335 129 344 2.79E-38 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_00950 c02b942d34191748afa71cdbb4a4ee8a 346 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 163 301 7.9E-31 T 31-10-2018 IPR006342 Methyltransferase FkbM DFR86_03100 607fa6892a3ba0b157e573ec74c37187 369 TIGRFAM TIGR02090 LEU1_arch: isopropylmalate/citramalate/homocitrate synthases 1 362 2.2E-170 T 31-10-2018 IPR011830 Isopropylmalate/citramalate/homocitrate synthase GO:0019752|GO:0046912 DFR86_03100 607fa6892a3ba0b157e573ec74c37187 369 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 187 200 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR86_03100 607fa6892a3ba0b157e573ec74c37187 369 SUPERFAMILY SSF51569 1 276 1.39E-98 T 31-10-2018 DFR86_03100 607fa6892a3ba0b157e573ec74c37187 369 Gene3D G3DSA:3.20.20.70 1 264 4.6E-105 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_03100 607fa6892a3ba0b157e573ec74c37187 369 Pfam PF00682 HMGL-like 1 258 1.8E-89 T 31-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 DFR86_03100 607fa6892a3ba0b157e573ec74c37187 369 Gene3D G3DSA:1.10.238.260 265 368 6.2E-31 T 31-10-2018 DFR86_03100 607fa6892a3ba0b157e573ec74c37187 369 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 6 22 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR86_06585 a41812651d0804fa11b92732bfc7e5a8 75 SUPERFAMILY SSF50182 6 73 1.56E-20 T 31-10-2018 IPR010920 LSM domain superfamily DFR86_06585 a41812651d0804fa11b92732bfc7e5a8 75 SMART SM00651 7 72 3.2E-24 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type DFR86_06585 a41812651d0804fa11b92732bfc7e5a8 75 Gene3D G3DSA:2.30.30.100 1 75 2.8E-26 T 31-10-2018 DFR86_06585 a41812651d0804fa11b92732bfc7e5a8 75 Pfam PF01423 LSM domain 8 72 9.1E-23 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type DFR86_08195 cc7b2907f85655b494bb94da7efbf766 417 SUPERFAMILY SSF111283 3 416 1.57E-57 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 DFR86_08195 cc7b2907f85655b494bb94da7efbf766 417 Gene3D G3DSA:3.30.2290.10 2 189 1.8E-17 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal DFR86_08195 cc7b2907f85655b494bb94da7efbf766 417 Pfam PF01523 Putative modulator of DNA gyrase 23 283 7.3E-33 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 DFR86_04590 e927412673dc27a32b243133d6e5b361 564 SUPERFAMILY SSF103473 4 454 1.16E-48 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_04590 e927412673dc27a32b243133d6e5b361 564 Pfam PF07690 Major Facilitator Superfamily 13 425 2.5E-39 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_04590 e927412673dc27a32b243133d6e5b361 564 Gene3D G3DSA:1.20.1250.20 8 228 5.4E-28 T 31-10-2018 DFR86_04590 e927412673dc27a32b243133d6e5b361 564 Gene3D G3DSA:1.20.1250.20 275 452 6.6E-18 T 31-10-2018 DFR86_02600 60b514c9b4cb70f2fbde9c3b60693847 81 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 81 2.0E-18 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 DFR86_02600 60b514c9b4cb70f2fbde9c3b60693847 81 SMART SM01103 1 79 9.4E-19 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 DFR86_02600 60b514c9b4cb70f2fbde9c3b60693847 81 Gene3D G3DSA:3.30.110.60 2 81 1.7E-18 T 31-10-2018 IPR035920 YhbY-like superfamily DFR86_02600 60b514c9b4cb70f2fbde9c3b60693847 81 SUPERFAMILY SSF75471 13 79 1.83E-15 T 31-10-2018 IPR035920 YhbY-like superfamily DFR86_02600 60b514c9b4cb70f2fbde9c3b60693847 81 Pfam PF01985 CRS1 / YhbY (CRM) domain 12 77 8.8E-14 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 DFR86_07480 39b30dce9375606bee16b1bcf28aa374 362 Gene3D G3DSA:3.40.50.410 40 205 5.9E-24 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR86_07480 39b30dce9375606bee16b1bcf28aa374 362 Pfam PF00092 von Willebrand factor type A domain 43 200 1.6E-17 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR86_07480 39b30dce9375606bee16b1bcf28aa374 362 SMART SM00327 38 203 4.7E-16 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR86_07480 39b30dce9375606bee16b1bcf28aa374 362 SUPERFAMILY SSF53300 39 201 5.09E-24 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR86_05445 9c1f6347cb460e9bec0f73910068feef 228 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 7 215 9.3E-35 T 31-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 DFR86_05445 9c1f6347cb460e9bec0f73910068feef 228 SUPERFAMILY SSF55681 6 169 6.79E-39 T 31-10-2018 DFR86_05445 9c1f6347cb460e9bec0f73910068feef 228 Pfam PF03099 Biotin/lipoate A/B protein ligase family 15 125 2.7E-12 T 31-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 DFR86_05445 9c1f6347cb460e9bec0f73910068feef 228 Gene3D G3DSA:3.30.930.10 3 182 5.8E-40 T 31-10-2018 DFR86_02485 8fd1049e5f2221da81f3ae9f95fc05dd 202 SUPERFAMILY SSF53335 3 169 8.33E-13 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_02485 8fd1049e5f2221da81f3ae9f95fc05dd 202 Pfam PF08241 Methyltransferase domain 37 115 2.6E-8 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR86_02485 8fd1049e5f2221da81f3ae9f95fc05dd 202 Gene3D G3DSA:3.40.50.150 7 199 7.6E-22 T 31-10-2018 DFR86_01955 5cfefaf9c1ca36d834053dc49fb0ff32 197 Gene3D G3DSA:3.90.850.10 2 196 8.6E-10 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR86_01955 5cfefaf9c1ca36d834053dc49fb0ff32 197 SUPERFAMILY SSF56529 3 194 2.29E-12 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR86_02470 ddb5c9bad91b6370010d341d47559f9a 878 SUPERFAMILY SSF52540 1 866 1.44E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_02470 ddb5c9bad91b6370010d341d47559f9a 878 SUPERFAMILY SSF75712 385 483 1.11E-17 T 31-10-2018 DFR86_02470 ddb5c9bad91b6370010d341d47559f9a 878 Pfam PF04423 Rad50 zinc hook motif 413 459 9.2E-13 T 31-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 DFR86_02470 ddb5c9bad91b6370010d341d47559f9a 878 SUPERFAMILY SSF57997 548 711 9.15E-9 T 31-10-2018 DFR86_02470 ddb5c9bad91b6370010d341d47559f9a 878 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 873 12.94 T 31-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type DFR86_02470 ddb5c9bad91b6370010d341d47559f9a 878 Gene3D G3DSA:1.10.287.510 382 492 7.2E-16 T 31-10-2018 DFR86_02470 ddb5c9bad91b6370010d341d47559f9a 878 Gene3D G3DSA:3.40.50.300 640 873 9.6E-41 T 31-10-2018 DFR86_02470 ddb5c9bad91b6370010d341d47559f9a 878 Gene3D G3DSA:3.40.50.300 1 298 5.1E-33 T 31-10-2018 DFR86_02470 ddb5c9bad91b6370010d341d47559f9a 878 Pfam PF13476 AAA domain 5 213 2.9E-19 T 31-10-2018 IPR038729 Rad50/SbcC-type AAA domain DFR86_01820 528aacfbb83ba0e117913b093ee44d93 167 Pfam PF00364 Biotin-requiring enzyme 103 166 1.6E-17 T 31-10-2018 IPR000089 Biotin/lipoyl attachment DFR86_01820 528aacfbb83ba0e117913b093ee44d93 167 Gene3D G3DSA:2.40.50.100 91 167 3.3E-23 T 31-10-2018 DFR86_01820 528aacfbb83ba0e117913b093ee44d93 167 SUPERFAMILY SSF51230 91 166 1.07E-20 T 31-10-2018 IPR011053 Single hybrid motif DFR86_10420 f4674fde20fc387be1c1b1cd2aa63da5 509 Pfam PF02538 Hydantoinase B/oxoprolinase 5 507 4.5E-177 T 31-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 DFR86_06080 f970415359e3dce0ad929af3da640caf 161 Pfam PF13456 Reverse transcriptase-like 17 129 1.4E-17 T 31-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 DFR86_06080 f970415359e3dce0ad929af3da640caf 161 SUPERFAMILY SSF53098 6 129 7.21E-21 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily DFR86_06080 f970415359e3dce0ad929af3da640caf 161 Gene3D G3DSA:3.30.420.10 3 150 2.8E-38 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 DFR86_09735 8e46d0bfe55e13b4c4035298877dd29a 123 SUPERFAMILY SSF46785 6 69 2.78E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_09735 8e46d0bfe55e13b4c4035298877dd29a 123 Pfam PF04182 B-block binding subunit of TFIIIC 14 63 8.0E-7 T 31-10-2018 IPR007309 B-block binding subunit of TFIIIC Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066 DFR86_09735 8e46d0bfe55e13b4c4035298877dd29a 123 Gene3D G3DSA:1.10.10.10 2 76 4.7E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_00150 0a1f070a3d3b70e3ac867c0393e11060 244 TIGRFAM TIGR02581 cas_cyan_RAMP: CRISPR-associated RAMP protein, SSO1426 family 7 220 4.9E-75 T 31-10-2018 IPR013411 CRISPR-associated RAMP TM1809 DFR86_00150 0a1f070a3d3b70e3ac867c0393e11060 244 Pfam PF03787 RAMP superfamily 18 214 6.8E-21 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_03590 00623b38d4b966fb86dd0dc42d96b27a 504 PIRSF PIRSF006060 1 503 5.2E-24 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_03590 00623b38d4b966fb86dd0dc42d96b27a 504 Pfam PF13520 Amino acid permease 28 469 3.2E-19 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_06090 40a6c3af747738155ba8cdc1f273b52b 326 Hamap MF_00288 Methionine synthase [metE]. 7 320 45.462 T 31-10-2018 IPR022921 Methionine synthase MetE, archaeal GO:0008168|GO:0009086 DFR86_06090 40a6c3af747738155ba8cdc1f273b52b 326 SUPERFAMILY SSF51726 9 324 4.06E-85 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 DFR86_06090 40a6c3af747738155ba8cdc1f273b52b 326 Gene3D G3DSA:3.20.20.210 2 326 1.6E-113 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 DFR86_06090 40a6c3af747738155ba8cdc1f273b52b 326 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 7 317 1.3E-62 T 31-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 DFR86_05315 2acfb3d3d4cd77c96e1713f827b17d7e 327 Pfam PF08542 Replication factor C C-terminal domain 226 313 3.3E-24 T 31-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 DFR86_05315 2acfb3d3d4cd77c96e1713f827b17d7e 327 SUPERFAMILY SSF52540 5 211 1.49E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_05315 2acfb3d3d4cd77c96e1713f827b17d7e 327 Hamap MF_01509 Replication factor C small subunit [rfcS]. 3 318 49.773 T 31-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 DFR86_05315 2acfb3d3d4cd77c96e1713f827b17d7e 327 Gene3D G3DSA:1.10.8.60 162 223 5.5E-20 T 31-10-2018 DFR86_05315 2acfb3d3d4cd77c96e1713f827b17d7e 327 SUPERFAMILY SSF48019 226 317 1.15E-22 T 31-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 DFR86_05315 2acfb3d3d4cd77c96e1713f827b17d7e 327 Gene3D G3DSA:1.20.272.10 225 320 6.5E-35 T 31-10-2018 DFR86_05315 2acfb3d3d4cd77c96e1713f827b17d7e 327 Gene3D G3DSA:3.40.50.300 1 160 4.7E-54 T 31-10-2018 DFR86_05315 2acfb3d3d4cd77c96e1713f827b17d7e 327 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 41 154 1.8E-15 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_05315 2acfb3d3d4cd77c96e1713f827b17d7e 327 SMART SM00382 37 164 1.4E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_04155 dd42e018ce5c85c0cd72c6be1deb7236 315 SUPERFAMILY SSF141130 3 308 3.92E-86 T 31-10-2018 DFR86_04155 dd42e018ce5c85c0cd72c6be1deb7236 315 Gene3D G3DSA:2.60.120.580 131 224 4.0E-32 T 31-10-2018 DFR86_04155 dd42e018ce5c85c0cd72c6be1deb7236 315 Gene3D G3DSA:2.60.120.580 2 123 1.8E-21 T 31-10-2018 DFR86_04155 dd42e018ce5c85c0cd72c6be1deb7236 315 Pfam PF03069 Acetamidase/Formamidase family 8 149 6.9E-25 T 31-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 DFR86_04155 dd42e018ce5c85c0cd72c6be1deb7236 315 Pfam PF03069 Acetamidase/Formamidase family 157 308 2.4E-42 T 31-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 DFR86_04155 dd42e018ce5c85c0cd72c6be1deb7236 315 Gene3D G3DSA:3.10.28.20 240 311 1.5E-7 T 31-10-2018 DFR86_06900 e6b38149d631395522dbd54ff05a90f4 87 Pfam PF01199 Ribosomal protein L34e 5 81 2.6E-19 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06900 e6b38149d631395522dbd54ff05a90f4 87 Gene3D G3DSA:3.40.1800.40 30 84 7.7E-11 T 31-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06900 e6b38149d631395522dbd54ff05a90f4 87 PRINTS PR01250 Ribosomal protein L34 signature 6 19 2.0E-17 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06900 e6b38149d631395522dbd54ff05a90f4 87 PRINTS PR01250 Ribosomal protein L34 signature 54 76 2.0E-17 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06900 e6b38149d631395522dbd54ff05a90f4 87 PRINTS PR01250 Ribosomal protein L34 signature 19 36 2.0E-17 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06900 e6b38149d631395522dbd54ff05a90f4 87 PRINTS PR01250 Ribosomal protein L34 signature 37 47 2.0E-17 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06900 e6b38149d631395522dbd54ff05a90f4 87 ProSitePatterns PS01145 Ribosomal protein L34e signature. 8 21 - T 31-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06900 e6b38149d631395522dbd54ff05a90f4 87 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 2 85 23.439 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_04310 be0cc3878e02d831a3ea08cf833731ea 473 Gene3D G3DSA:1.20.1740.10 21 470 2.3E-26 T 31-10-2018 DFR86_04310 be0cc3878e02d831a3ea08cf833731ea 473 PIRSF PIRSF006060 1 468 3.2E-52 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04310 be0cc3878e02d831a3ea08cf833731ea 473 Pfam PF00324 Amino acid permease 53 428 8.1E-20 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR86_10305 b54a27a1961483866e292a54d1ab5c59 123 Gene3D G3DSA:2.60.40.790 2 122 1.7E-28 T 31-10-2018 IPR008978 HSP20-like chaperone DFR86_10305 b54a27a1961483866e292a54d1ab5c59 123 Pfam PF00011 Hsp20/alpha crystallin family 29 115 9.2E-8 T 31-10-2018 IPR002068 Alpha crystallin/Hsp20 domain DFR86_10305 b54a27a1961483866e292a54d1ab5c59 123 SUPERFAMILY SSF49764 18 119 2.02E-17 T 31-10-2018 IPR008978 HSP20-like chaperone DFR86_08985 8a1cd2a8add29a7fa2404d4dd1137210 328 SUPERFAMILY SSF56747 11 323 3.49E-87 T 31-10-2018 DFR86_08985 8a1cd2a8add29a7fa2404d4dd1137210 328 Gene3D G3DSA:3.90.920.30 1 328 7.4E-116 T 31-10-2018 DFR86_08985 8a1cd2a8add29a7fa2404d4dd1137210 328 Hamap MF_00700 DNA primase small subunit PriS [priS]. 12 319 27.03 T 31-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 DFR86_08985 8a1cd2a8add29a7fa2404d4dd1137210 328 Pfam PF01896 DNA primase small subunit 140 210 7.6E-7 T 31-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 DFR86_11310 7dc1d5586fb988cf72f1be6ce44db4e6 364 Gene3D G3DSA:2.40.110.10 126 234 1.3E-36 T 31-10-2018 DFR86_11310 7dc1d5586fb988cf72f1be6ce44db4e6 364 Gene3D G3DSA:1.20.140.10 235 364 2.8E-16 T 31-10-2018 DFR86_11310 7dc1d5586fb988cf72f1be6ce44db4e6 364 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 122 4.0E-27 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 DFR86_11310 7dc1d5586fb988cf72f1be6ce44db4e6 364 Gene3D G3DSA:1.10.540.10 2 120 2.6E-28 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 DFR86_11310 7dc1d5586fb988cf72f1be6ce44db4e6 364 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 267 359 1.9E-6 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DFR86_11310 7dc1d5586fb988cf72f1be6ce44db4e6 364 SUPERFAMILY SSF56645 4 243 9.82E-72 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR86_11310 7dc1d5586fb988cf72f1be6ce44db4e6 364 SUPERFAMILY SSF47203 230 362 5.33E-12 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR86_11310 7dc1d5586fb988cf72f1be6ce44db4e6 364 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 209 5.5E-21 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 DFR86_05420 2fb2d23dc8a7868c4d06db2d606b1642 388 Pfam PF07690 Major Facilitator Superfamily 15 253 2.1E-13 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_05420 2fb2d23dc8a7868c4d06db2d606b1642 388 Gene3D G3DSA:1.20.1250.20 266 382 7.9E-10 T 31-10-2018 DFR86_05420 2fb2d23dc8a7868c4d06db2d606b1642 388 Gene3D G3DSA:1.20.1250.20 5 265 7.0E-16 T 31-10-2018 DFR86_05420 2fb2d23dc8a7868c4d06db2d606b1642 388 SUPERFAMILY SSF103473 11 379 4.84E-34 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_03910 94a8336781aa9441c7cb18528e989f19 223 Pfam PF00355 Rieske [2Fe-2S] domain 88 171 1.6E-9 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR86_03910 94a8336781aa9441c7cb18528e989f19 223 SUPERFAMILY SSF50022 86 209 1.57E-22 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_03910 94a8336781aa9441c7cb18528e989f19 223 Gene3D G3DSA:2.102.10.10 82 211 3.1E-27 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_03910 94a8336781aa9441c7cb18528e989f19 223 TIGRFAM TIGR02694 arsenite_ox_S: arsenite oxidase, small subunit 85 210 1.3E-33 T 31-10-2018 IPR014067 Arsenite oxidase, small subunit MetaCyc: PWY-7429 DFR86_10530 7d36cb6199eb52aedaa206fe7a149d1d 438 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 347 373 1.8E-13 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_10530 7d36cb6199eb52aedaa206fe7a149d1d 438 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 117 136 1.8E-13 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_10530 7d36cb6199eb52aedaa206fe7a149d1d 438 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 218 242 1.8E-13 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_10530 7d36cb6199eb52aedaa206fe7a149d1d 438 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 297 316 1.8E-13 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_10530 7d36cb6199eb52aedaa206fe7a149d1d 438 Pfam PF00361 Proton-conducting membrane transporter 112 386 6.4E-44 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_00515 f2f6183c470a57b539ee81c28f2da436 185 SUPERFAMILY SSF53323 2 181 6.28E-46 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR86_00515 f2f6183c470a57b539ee81c28f2da436 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 178 3.7E-66 T 31-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 DFR86_00515 f2f6183c470a57b539ee81c28f2da436 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 175 4.1E-36 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DFR86_00515 f2f6183c470a57b539ee81c28f2da436 185 Gene3D G3DSA:3.40.920.10 1 180 4.1E-56 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR86_01620 e9e16fd0c0e00dca44f349b3846d6ed5 654 ProSitePatterns PS00455 Putative AMP-binding domain signature. 257 268 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR86_01620 e9e16fd0c0e00dca44f349b3846d6ed5 654 Gene3D G3DSA:3.30.300.30 522 651 8.7E-28 T 31-10-2018 DFR86_01620 e9e16fd0c0e00dca44f349b3846d6ed5 654 SUPERFAMILY SSF56801 14 640 2.09E-152 T 31-10-2018 DFR86_01620 e9e16fd0c0e00dca44f349b3846d6ed5 654 Pfam PF00501 AMP-binding enzyme 89 525 5.5E-82 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR86_01620 e9e16fd0c0e00dca44f349b3846d6ed5 654 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 643 5.1E-230 T 31-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 DFR86_01620 e9e16fd0c0e00dca44f349b3846d6ed5 654 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 78 8.3E-19 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR86_01620 e9e16fd0c0e00dca44f349b3846d6ed5 654 Gene3D G3DSA:3.40.50.12780 51 519 9.5E-93 T 31-10-2018 DFR86_01620 e9e16fd0c0e00dca44f349b3846d6ed5 654 Pfam PF13193 AMP-binding enzyme C-terminal domain 534 611 1.9E-25 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR86_06000 c541bd7357eaa43bc5b2f2e3b873a90f 110 ProDom PD289296 ST0369 SSO0428 4 110 1.0E-12 T 31-10-2018 IPR020330 Uncharacterised protein family SSO0428 DFR86_10455 e0fcaa6f7fa988684c310dd6286d01cd 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 31-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 DFR86_10455 e0fcaa6f7fa988684c310dd6286d01cd 494 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 31-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 DFR86_10455 e0fcaa6f7fa988684c310dd6286d01cd 494 Gene3D G3DSA:3.40.309.10 253 446 1.4E-164 T 31-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 DFR86_10455 e0fcaa6f7fa988684c310dd6286d01cd 494 Gene3D G3DSA:3.40.605.10 9 474 1.4E-164 T 31-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 DFR86_10455 e0fcaa6f7fa988684c310dd6286d01cd 494 SUPERFAMILY SSF53720 4 481 1.57E-158 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 DFR86_10455 e0fcaa6f7fa988684c310dd6286d01cd 494 Pfam PF00171 Aldehyde dehydrogenase family 13 476 7.6E-163 T 31-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 DFR86_05225 91722777d231233d5634d54121b754b9 484 SUPERFAMILY SSF103473 6 190 1.83E-41 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_05225 91722777d231233d5634d54121b754b9 484 Gene3D G3DSA:1.20.1250.20 198 470 1.1E-10 T 31-10-2018 DFR86_05225 91722777d231233d5634d54121b754b9 484 Gene3D G3DSA:1.20.1250.20 6 197 1.1E-41 T 31-10-2018 DFR86_05225 91722777d231233d5634d54121b754b9 484 Pfam PF07690 Major Facilitator Superfamily 18 414 4.0E-46 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_05225 91722777d231233d5634d54121b754b9 484 SUPERFAMILY SSF103473 202 473 3.53E-18 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_01445 d547d44e58925255ad769b7361854f0b 129 SUPERFAMILY SSF46785 14 112 2.62E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_01445 d547d44e58925255ad769b7361854f0b 129 Gene3D G3DSA:1.10.10.10 12 115 4.8E-23 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_01445 d547d44e58925255ad769b7361854f0b 129 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 23 82 8.4E-10 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR86_03690 2887d131055828e304af456f0758886d 234 Pfam PF13240 zinc-ribbon domain 4 23 3.5E-7 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR86_05985 dc8fad66c156d1879f3875a11777d680 325 SUPERFAMILY SSF51430 1 309 1.57E-60 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR86_05985 dc8fad66c156d1879f3875a11777d680 325 Pfam PF00248 Aldo/keto reductase family 15 305 1.3E-47 T 31-10-2018 IPR023210 NADP-dependent oxidoreductase domain DFR86_05985 dc8fad66c156d1879f3875a11777d680 325 Gene3D G3DSA:3.20.20.100 1 306 6.1E-60 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR86_07520 673763b5f844fa9108bd153986b73ccb 152 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 31 104 2.8E-25 T 31-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 DFR86_10460 65dd512bcd44d81df058ec82eb9a8c73 333 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 262 2.6E-51 T 31-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic DFR86_10460 65dd512bcd44d81df058ec82eb9a8c73 333 SUPERFAMILY SSF51445 2 231 2.53E-51 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR86_10460 65dd512bcd44d81df058ec82eb9a8c73 333 Gene3D G3DSA:3.20.20.70 1 233 3.4E-51 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_00490 399b1c113db0d64ba505dbb9d2e6d6e4 262 SUPERFAMILY SSF51621 2 214 6.67E-48 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR86_00490 399b1c113db0d64ba505dbb9d2e6d6e4 262 Gene3D G3DSA:3.20.20.60 1 262 2.9E-72 T 31-10-2018 DFR86_00490 399b1c113db0d64ba505dbb9d2e6d6e4 262 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 3 203 4.1E-27 T 31-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 DFR86_00490 399b1c113db0d64ba505dbb9d2e6d6e4 262 PIRSF PIRSF015582 1 262 7.6E-69 T 31-10-2018 IPR011206 Citrate lyase beta subunit-like DFR86_04060 c527c60f4a4f1f00691e34cc14111260 445 Pfam PF03916 Polysulphide reductase, NrfD 43 357 6.9E-50 T 31-10-2018 IPR005614 NrfD family DFR86_06345 941162234516b973065c317972e14f1a 464 SUPERFAMILY SSF51905 1 460 9.28E-32 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_06345 941162234516b973065c317972e14f1a 464 Gene3D G3DSA:3.50.50.60 1 118 6.3E-19 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_06345 941162234516b973065c317972e14f1a 464 Gene3D G3DSA:3.50.50.60 119 225 5.5E-8 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_06345 941162234516b973065c317972e14f1a 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 49 7.6E-7 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_06345 941162234516b973065c317972e14f1a 464 PIRSF PIRSF038984 2 121 1.2E-9 T 31-10-2018 IPR028348 FAD dependent protein DFR86_06345 941162234516b973065c317972e14f1a 464 PIRSF PIRSF038984 116 463 6.9E-29 T 31-10-2018 IPR028348 FAD dependent protein DFR86_06345 941162234516b973065c317972e14f1a 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.8E-8 T 31-10-2018 DFR86_06345 941162234516b973065c317972e14f1a 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 415 437 2.8E-8 T 31-10-2018 DFR86_11540 68a739b359e7d4cf3d686c0e329e67d4 203 SUPERFAMILY SSF52980 37 180 4.02E-7 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR86_11540 68a739b359e7d4cf3d686c0e329e67d4 203 Gene3D G3DSA:3.40.50.11700 2 134 1.1E-9 T 31-10-2018 DFR86_11540 68a739b359e7d4cf3d686c0e329e67d4 203 Pfam PF13412 Winged helix-turn-helix DNA-binding 146 184 1.6E-6 T 31-10-2018 DFR86_11540 68a739b359e7d4cf3d686c0e329e67d4 203 Gene3D G3DSA:1.10.10.10 135 196 1.9E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_11540 68a739b359e7d4cf3d686c0e329e67d4 203 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 3 189 1.0E-30 T 31-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 Gene3D G3DSA:3.30.1330.10 388 535 7.7E-40 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 SUPERFAMILY SSF55326 3 184 2.39E-45 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 SUPERFAMILY SSF55326 388 532 3.4E-34 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 Gene3D G3DSA:3.90.650.10 17 347 1.3E-113 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 SUPERFAMILY SSF56042 545 681 2.99E-17 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 PIRSF PIRSF001587 1 702 1.5E-212 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 Gene3D G3DSA:3.90.650.10 540 698 7.2E-15 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 Pfam PF02769 AIR synthase related protein, C-terminal domain 190 333 1.1E-27 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 Pfam PF02769 AIR synthase related protein, C-terminal domain 593 679 1.6E-10 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 5 692 1.5E-242 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 703 188.897 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 Gene3D G3DSA:3.30.1330.10 31 182 1.3E-113 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 Pfam PF00586 AIR synthase related protein, N-terminal domain 427 531 9.0E-14 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 Pfam PF00586 AIR synthase related protein, N-terminal domain 73 178 1.7E-21 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR86_08335 99dbb46d5379acfe85fd6458c193dcb7 703 SUPERFAMILY SSF56042 189 354 3.44E-35 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_00240 057507f3365cefeb3e50c498546112a9 216 SUPERFAMILY SSF53098 28 156 4.11E-6 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily DFR86_01490 619215b702138e1d6f57e1c832b2d69a 265 SUPERFAMILY SSF56281 20 243 1.05E-24 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_01490 619215b702138e1d6f57e1c832b2d69a 265 Pfam PF00753 Metallo-beta-lactamase superfamily 43 166 3.5E-5 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_01490 619215b702138e1d6f57e1c832b2d69a 265 SMART SM00849 12 177 2.0E-12 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_01490 619215b702138e1d6f57e1c832b2d69a 265 Gene3D G3DSA:3.60.15.10 6 200 1.3E-20 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_02255 b8595e4820de3fb65fa965c977d4dbcf 654 SUPERFAMILY SSF54862 545 639 1.51E-11 T 31-10-2018 DFR86_02255 b8595e4820de3fb65fa965c977d4dbcf 654 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 621 632 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_02255 b8595e4820de3fb65fa965c977d4dbcf 654 Pfam PF00037 4Fe-4S binding domain 620 634 4.8E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_02255 b8595e4820de3fb65fa965c977d4dbcf 654 Gene3D G3DSA:3.30.70.20 573 650 3.1E-8 T 31-10-2018 DFR86_08550 d6768e13b948c537e497cbc4b615c679 93 Pfam PF02680 Uncharacterized ArCR, COG1888 3 89 4.7E-34 T 31-10-2018 IPR003831 Protein of unknown function DUF211 DFR86_08550 d6768e13b948c537e497cbc4b615c679 93 Gene3D G3DSA:3.30.70.1340 1 86 4.2E-32 T 31-10-2018 IPR023129 MTH889-like domain superfamily DFR86_08550 d6768e13b948c537e497cbc4b615c679 93 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 10 88 7.0E-28 T 31-10-2018 IPR003831 Protein of unknown function DUF211 DFR86_08550 d6768e13b948c537e497cbc4b615c679 93 SUPERFAMILY SSF160363 2 91 7.72E-32 T 31-10-2018 IPR023129 MTH889-like domain superfamily DFR86_00640 b9458620849c2dfb11d1e3cc0c154afb 155 Pfam PF04116 Fatty acid hydroxylase superfamily 11 139 6.4E-11 T 31-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 DFR86_01875 c680deb9509b4471f8e51925e2123a04 304 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 9 291 2.0E-130 T 31-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate DFR86_01875 c680deb9509b4471f8e51925e2123a04 304 Gene3D G3DSA:3.40.50.970 20 197 1.2E-22 T 31-10-2018 DFR86_01875 c680deb9509b4471f8e51925e2123a04 304 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 197 268 6.0E-25 T 31-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal DFR86_01875 c680deb9509b4471f8e51925e2123a04 304 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 45 193 1.7E-29 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR86_01875 c680deb9509b4471f8e51925e2123a04 304 SUPERFAMILY SSF52518 10 279 1.25E-76 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_08065 6f30ba18da5b39fbc690b6b300a851b5 105 SUPERFAMILY SSF46785 2 94 2.04E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_08065 6f30ba18da5b39fbc690b6b300a851b5 105 Gene3D G3DSA:1.10.10.10 7 66 1.4E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_08065 6f30ba18da5b39fbc690b6b300a851b5 105 PIRSF PIRSF032840 1 104 9.6E-42 T 31-10-2018 IPR017009 Uncharacterised conserved protein UCP032840 DFR86_08065 6f30ba18da5b39fbc690b6b300a851b5 105 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 50 7.8E-6 T 31-10-2018 DFR86_05055 60cc6b69b7dff40e75eb7ccd53954781 461 Pfam PF00083 Sugar (and other) transporter 28 449 3.4E-52 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR86_05055 60cc6b69b7dff40e75eb7ccd53954781 461 SUPERFAMILY SSF103473 9 448 3.4E-56 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_05055 60cc6b69b7dff40e75eb7ccd53954781 461 ProSitePatterns PS00216 Sugar transport proteins signature 1. 311 327 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_05055 60cc6b69b7dff40e75eb7ccd53954781 461 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_05250 146dc03d715c6c84ff0e4592d78f939f 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 124 141 4.6E-18 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_05250 146dc03d715c6c84ff0e4592d78f939f 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 68 86 4.6E-18 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_05250 146dc03d715c6c84ff0e4592d78f939f 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 100 116 4.6E-18 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_05250 146dc03d715c6c84ff0e4592d78f939f 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 4.6E-18 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_05250 146dc03d715c6c84ff0e4592d78f939f 288 Gene3D G3DSA:3.20.20.70 1 285 1.9E-73 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_05250 146dc03d715c6c84ff0e4592d78f939f 288 Pfam PF00701 Dihydrodipicolinate synthetase family 2 271 5.0E-65 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_05250 146dc03d715c6c84ff0e4592d78f939f 288 SUPERFAMILY SSF51569 2 270 1.57E-67 T 31-10-2018 DFR86_05250 146dc03d715c6c84ff0e4592d78f939f 288 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 129 159 - T 31-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 DFR86_05250 146dc03d715c6c84ff0e4592d78f939f 288 PIRSF PIRSF001365 1 279 1.5E-68 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_05250 146dc03d715c6c84ff0e4592d78f939f 288 SMART SM01130 1 287 1.1E-67 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR86_05660 2c045f8848f79d4c0b9248343e12f586 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 3.9E-6 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR86_05660 2c045f8848f79d4c0b9248343e12f586 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 3.9E-6 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR86_05660 2c045f8848f79d4c0b9248343e12f586 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 3.9E-6 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR86_05660 2c045f8848f79d4c0b9248343e12f586 253 SUPERFAMILY SSF53474 3 253 5.08E-50 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_05660 2c045f8848f79d4c0b9248343e12f586 253 Gene3D G3DSA:3.40.50.1820 5 253 4.1E-49 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_05660 2c045f8848f79d4c0b9248343e12f586 253 Pfam PF00561 alpha/beta hydrolase fold 20 119 3.6E-17 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR86_09100 abbdd15e0737fc89f8ff8322dcc00c6c 322 Pfam PF13353 4Fe-4S single cluster domain 24 125 6.6E-9 T 31-10-2018 DFR86_09100 abbdd15e0737fc89f8ff8322dcc00c6c 322 Pfam PF04055 Radical SAM superfamily 29 135 1.4E-14 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_09100 abbdd15e0737fc89f8ff8322dcc00c6c 322 Gene3D G3DSA:3.20.20.70 21 294 2.3E-34 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_09100 abbdd15e0737fc89f8ff8322dcc00c6c 322 SUPERFAMILY SSF102114 23 284 6.28E-42 T 31-10-2018 DFR86_09100 abbdd15e0737fc89f8ff8322dcc00c6c 322 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 30 41 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR86_09410 41c39229932e88c49fd367af9e473be0 139 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 2 134 1.3E-24 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 DFR86_09410 41c39229932e88c49fd367af9e473be0 139 SUPERFAMILY SSF51306 22 83 4.34E-7 T 31-10-2018 IPR036286 LexA/Signal peptidase-like superfamily DFR86_05460 76b66cecbcfe796766f01859af9a814b 395 Pfam PF13660 Domain of unknown function (DUF4147) 2 216 1.7E-55 T 31-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 DFR86_05460 76b66cecbcfe796766f01859af9a814b 395 Gene3D G3DSA:3.40.1480.10 238 391 8.3E-97 T 31-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily DFR86_05460 76b66cecbcfe796766f01859af9a814b 395 SUPERFAMILY SSF82544 2 394 5.89E-92 T 31-10-2018 DFR86_05460 76b66cecbcfe796766f01859af9a814b 395 Gene3D G3DSA:3.40.50.10180 17 237 8.3E-97 T 31-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 DFR86_05460 76b66cecbcfe796766f01859af9a814b 395 Pfam PF05161 MOFRL family 290 388 3.2E-24 T 31-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 DFR86_03835 ceca5dc52664c22822127d29fd89e55f 253 Gene3D G3DSA:3.40.50.300 2 229 2.6E-29 T 31-10-2018 DFR86_03835 ceca5dc52664c22822127d29fd89e55f 253 SUPERFAMILY SSF52540 2 195 1.63E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03835 ceca5dc52664c22822127d29fd89e55f 253 Pfam PF00005 ABC transporter 17 140 9.9E-16 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_02820 b81fb1a69b5a7aa4543c7935925c816d 483 PIRSF PIRSF019435 1 483 4.7E-133 T 31-10-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like DFR86_02820 b81fb1a69b5a7aa4543c7935925c816d 483 Pfam PF05626 Protein of unknown function (DUF790) 1 375 4.2E-114 T 31-10-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like DFR86_02665 d80506eac1292cf5b0f388c1d941bb65 113 Gene3D G3DSA:2.20.28.10 4 101 3.9E-26 T 31-10-2018 DFR86_02665 d80506eac1292cf5b0f388c1d941bb65 113 SUPERFAMILY SSF46785 2 100 6.67E-30 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_05005 7850787476d444e47da3a71ec4a00e45 287 Gene3D G3DSA:3.50.50.60 3 281 5.7E-23 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05005 7850787476d444e47da3a71ec4a00e45 287 SUPERFAMILY SSF51905 1 245 1.19E-10 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_07920 d963d6d384c9d7ea2dca94ac4dab49c7 255 PIRSF PIRSF006648 2 253 8.3E-57 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 DFR86_07920 d963d6d384c9d7ea2dca94ac4dab49c7 255 Pfam PF01061 ABC-2 type transporter 7 220 3.0E-25 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 DFR86_03295 541a8d5de538ebe50b304b388a5869c6 385 Gene3D G3DSA:3.40.50.300 6 208 2.1E-46 T 31-10-2018 DFR86_03295 541a8d5de538ebe50b304b388a5869c6 385 Pfam PF07728 AAA domain (dynein-related subfamily) 43 170 1.1E-27 T 31-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 DFR86_03295 541a8d5de538ebe50b304b388a5869c6 385 SMART SM00382 40 180 2.7E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_03295 541a8d5de538ebe50b304b388a5869c6 385 SUPERFAMILY SSF52540 10 195 4.2E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07010 d6cc1f14ca880b587e7fea387936476d 225 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 14 216 6.5E-19 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_07010 d6cc1f14ca880b587e7fea387936476d 225 SMART SM00934 14 217 6.8E-35 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR86_07010 d6cc1f14ca880b587e7fea387936476d 225 SUPERFAMILY SSF51366 15 221 7.33E-33 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR86_07010 d6cc1f14ca880b587e7fea387936476d 225 Gene3D G3DSA:3.20.20.70 14 224 4.5E-63 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_11295 d73c29abeb3fd276d004957841e4321d 249 Pfam PF04240 Carotenoid biosynthesis protein 24 177 1.3E-25 T 31-10-2018 IPR007354 Carotene biosynthesis associated membrane protein DFR86_06560 86050bf4608f65343a853240db627a98 364 SUPERFAMILY SSF52540 179 358 1.18E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_06560 86050bf4608f65343a853240db627a98 364 Pfam PF01926 50S ribosome-binding GTPase 181 300 1.1E-17 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_06560 86050bf4608f65343a853240db627a98 364 Gene3D G3DSA:3.40.50.300 178 362 1.7E-45 T 31-10-2018 DFR86_06560 86050bf4608f65343a853240db627a98 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 202 220 6.4E-6 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_06560 86050bf4608f65343a853240db627a98 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 181 201 6.4E-6 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_06560 86050bf4608f65343a853240db627a98 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 247 265 6.4E-6 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR86_06560 86050bf4608f65343a853240db627a98 364 Pfam PF16360 GTP-binding GTPase Middle Region 96 173 8.8E-17 T 31-10-2018 IPR032305 GTP-binding protein, middle domain DFR86_06560 86050bf4608f65343a853240db627a98 364 PIRSF PIRSF006809 6 363 3.1E-91 T 31-10-2018 IPR016496 GTPase HflX GO:0005525 DFR86_06560 86050bf4608f65343a853240db627a98 364 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 13 351 4.3E-68 T 31-10-2018 IPR016496 GTPase HflX GO:0005525 DFR86_06560 86050bf4608f65343a853240db627a98 364 Gene3D G3DSA:3.40.50.11060 2 122 7.8E-30 T 31-10-2018 DFR86_06560 86050bf4608f65343a853240db627a98 364 Pfam PF13167 GTP-binding GTPase N-terminal 13 94 1.5E-11 T 31-10-2018 IPR025121 GTPase HflX, N-terminal DFR86_07265 186c8ce32a71826d4fdbb7769cab1b72 195 Pfam PF01380 SIS domain 36 133 2.2E-17 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR86_07265 186c8ce32a71826d4fdbb7769cab1b72 195 Gene3D G3DSA:3.40.50.10490 1 194 5.5E-52 T 31-10-2018 DFR86_07265 186c8ce32a71826d4fdbb7769cab1b72 195 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 3 194 9.2E-68 T 31-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 DFR86_07265 186c8ce32a71826d4fdbb7769cab1b72 195 SUPERFAMILY SSF53697 3 193 2.09E-36 T 31-10-2018 DFR86_06965 d09f37d2685dcc6810e95abd522be228 167 Gene3D G3DSA:3.40.630.30 3 167 2.3E-53 T 31-10-2018 DFR86_06965 d09f37d2685dcc6810e95abd522be228 167 SUPERFAMILY SSF55729 11 167 3.27E-35 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR86_06965 d09f37d2685dcc6810e95abd522be228 167 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 20 163 2.8E-28 T 31-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 DFR86_06965 d09f37d2685dcc6810e95abd522be228 167 Pfam PF00583 Acetyltransferase (GNAT) family 29 144 3.2E-20 T 31-10-2018 IPR000182 GNAT domain DFR86_00165 0bccb07514e8f5a22a2af781caa68b4a 863 Gene3D G3DSA:3.30.70.2230 545 712 6.3E-8 T 31-10-2018 DFR86_00165 0bccb07514e8f5a22a2af781caa68b4a 863 Pfam PF01966 HD domain 157 242 7.9E-8 T 31-10-2018 IPR006674 HD domain DFR86_00165 0bccb07514e8f5a22a2af781caa68b4a 863 SUPERFAMILY SSF109604 158 237 2.38E-9 T 31-10-2018 DFR86_00165 0bccb07514e8f5a22a2af781caa68b4a 863 Gene3D G3DSA:1.10.3210.10 105 254 5.2E-9 T 31-10-2018 DFR86_08475 0729173375925c36e7cae49512253d57 455 Gene3D G3DSA:1.10.287.40 6 105 9.0E-20 T 31-10-2018 DFR86_08475 0729173375925c36e7cae49512253d57 455 PIRSF PIRSF001529 5 149 9.4E-23 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR86_08475 0729173375925c36e7cae49512253d57 455 PIRSF PIRSF001529 138 446 9.4E-110 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR86_08475 0729173375925c36e7cae49512253d57 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 242 421 1.7E-37 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR86_08475 0729173375925c36e7cae49512253d57 455 SUPERFAMILY SSF55681 162 438 4.7E-74 T 31-10-2018 DFR86_08475 0729173375925c36e7cae49512253d57 455 Gene3D G3DSA:3.30.930.10 106 447 9.0E-118 T 31-10-2018 DFR86_08475 0729173375925c36e7cae49512253d57 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 7 438 1.2E-138 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR86_08475 0729173375925c36e7cae49512253d57 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 7 107 1.7E-19 T 31-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 DFR86_08475 0729173375925c36e7cae49512253d57 455 SUPERFAMILY SSF46589 7 113 2.62E-21 T 31-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 DFR86_08475 0729173375925c36e7cae49512253d57 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 9.5E-30 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR86_08475 0729173375925c36e7cae49512253d57 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 9.5E-30 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR86_08475 0729173375925c36e7cae49512253d57 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 9.5E-30 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR86_08475 0729173375925c36e7cae49512253d57 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 9.5E-30 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR86_08475 0729173375925c36e7cae49512253d57 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 9.5E-30 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR86_08475 0729173375925c36e7cae49512253d57 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 3 443 36.711 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR86_01300 f13062135a3a118d269a92b9f2c272f2 172 SUPERFAMILY SSF49503 59 171 2.32E-18 T 31-10-2018 IPR008972 Cupredoxin DFR86_01300 f13062135a3a118d269a92b9f2c272f2 172 Gene3D G3DSA:2.60.40.420 56 172 2.3E-11 T 31-10-2018 IPR008972 Cupredoxin DFR86_06640 b03797f505a0aceb36ce708ce84b740f 200 Pfam PF05175 Methyltransferase small domain 27 115 1.1E-10 T 31-10-2018 IPR007848 Methyltransferase small domain GO:0008168 DFR86_06640 b03797f505a0aceb36ce708ce84b740f 200 SUPERFAMILY SSF53335 7 174 2.72E-30 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_06640 b03797f505a0aceb36ce708ce84b740f 200 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 109 115 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DFR86_06640 b03797f505a0aceb36ce708ce84b740f 200 Gene3D G3DSA:3.40.50.150 18 199 6.0E-34 T 31-10-2018 DFR86_06640 b03797f505a0aceb36ce708ce84b740f 200 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 21 192 4.5E-36 T 31-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 DFR86_01380 36fdd46d677e8a98d68589a340d0df69 116 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 23 91 4.0E-9 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR86_01380 36fdd46d677e8a98d68589a340d0df69 116 Gene3D G3DSA:1.10.10.10 7 115 1.5E-35 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_01380 36fdd46d677e8a98d68589a340d0df69 116 SUPERFAMILY SSF46785 16 105 1.28E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_10225 1479ca776faca5513cf837de1e7158c0 112 Pfam PF02656 Domain of unknown function (DUF202) 7 79 8.1E-21 T 31-10-2018 IPR003807 Domain of unknown function DUF202 DFR86_11575 a545daf71de925010c654a90c3176107 290 Gene3D G3DSA:3.30.70.2990 1 121 2.8E-53 T 31-10-2018 DFR86_11575 a545daf71de925010c654a90c3176107 290 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 46 278 6.0E-20 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 DFR86_11575 a545daf71de925010c654a90c3176107 290 Gene3D G3DSA:3.30.70.1900 122 289 7.1E-60 T 31-10-2018 DFR86_11575 a545daf71de925010c654a90c3176107 290 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 140 277 2.0E-9 T 31-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal DFR86_08585 087d3e09407a9b6063584fbb09579387 161 Gene3D G3DSA:3.40.50.1000 2 161 1.1E-23 T 31-10-2018 IPR023214 HAD superfamily DFR86_08585 087d3e09407a9b6063584fbb09579387 161 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 3 160 1.4E-49 T 31-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 DFR86_08585 087d3e09407a9b6063584fbb09579387 161 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 4 138 9.1E-28 T 31-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC DFR86_08585 087d3e09407a9b6063584fbb09579387 161 Pfam PF12689 Acid Phosphatase 4 128 5.2E-13 T 31-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 DFR86_08585 087d3e09407a9b6063584fbb09579387 161 SUPERFAMILY SSF56784 1 129 1.97E-21 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_05065 9e8d6a82579076fcd93800b49c61437c 126 Pfam PF07883 Cupin domain 44 109 1.6E-14 T 31-10-2018 IPR013096 Cupin 2, conserved barrel DFR86_05065 9e8d6a82579076fcd93800b49c61437c 126 SUPERFAMILY SSF51182 10 118 2.89E-23 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily DFR86_05065 9e8d6a82579076fcd93800b49c61437c 126 Gene3D G3DSA:2.60.120.10 4 123 9.4E-26 T 31-10-2018 IPR014710 RmlC-like jelly roll fold DFR86_03830 207ae9462a14c3b34d54041601ca9a16 290 Gene3D G3DSA:3.40.50.300 1 244 1.6E-50 T 31-10-2018 DFR86_03830 207ae9462a14c3b34d54041601ca9a16 290 SMART SM00382 27 218 7.7E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_03830 207ae9462a14c3b34d54041601ca9a16 290 Pfam PF00005 ABC transporter 18 157 5.8E-26 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_03830 207ae9462a14c3b34d54041601ca9a16 290 SUPERFAMILY SSF52540 2 221 2.09E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_11055 0e5f5aa30467d2842b62dab6758bf68a 313 Pfam PF01206 Sulfurtransferase TusA 135 196 1.5E-12 T 31-10-2018 IPR001455 TusA-like domain DFR86_11055 0e5f5aa30467d2842b62dab6758bf68a 313 Gene3D G3DSA:3.30.110.40 132 201 1.5E-9 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_11055 0e5f5aa30467d2842b62dab6758bf68a 313 SUPERFAMILY SSF64307 125 195 1.83E-12 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_10525 044f558dc3d52dbcfdb2431d643f4cfa 331 Gene3D G3DSA:1.10.10.10 165 215 1.3E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10525 044f558dc3d52dbcfdb2431d643f4cfa 331 Pfam PF13412 Winged helix-turn-helix DNA-binding 166 204 3.0E-6 T 31-10-2018 DFR86_09360 0256554da0a32f17e2f8d7b84affae3d 379 SUPERFAMILY SSF101960 21 373 1.03E-53 T 31-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily DFR86_09360 0256554da0a32f17e2f8d7b84affae3d 379 Pfam PF01458 Uncharacterized protein family (UPF0051) 140 356 7.8E-39 T 31-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 DFR86_10865 3983c0712b8839e094bbd2ef6dba7230 139 Pfam PF02566 OsmC-like protein 33 132 4.7E-17 T 31-10-2018 IPR003718 OsmC/Ohr family DFR86_10865 3983c0712b8839e094bbd2ef6dba7230 139 SUPERFAMILY SSF82784 3 134 4.84E-23 T 31-10-2018 IPR036102 OsmC/Ohr superfamily DFR86_10865 3983c0712b8839e094bbd2ef6dba7230 139 Gene3D G3DSA:3.30.300.20 2 124 1.2E-19 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR86_07055 acd96759af679c7538f178ecf0883f68 179 Pfam PF01927 Mut7-C RNAse domain 5 135 5.0E-30 T 31-10-2018 IPR002782 Mut7-C RNAse domain DFR86_07440 7c5158caa72085e1f96cbc48fcdde55b 221 Pfam PF13743 Thioredoxin 6 185 1.9E-21 T 31-10-2018 DFR86_07440 7c5158caa72085e1f96cbc48fcdde55b 221 SUPERFAMILY SSF52833 2 208 7.85E-38 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_07440 7c5158caa72085e1f96cbc48fcdde55b 221 Gene3D G3DSA:3.40.30.10 1 208 4.7E-36 T 31-10-2018 DFR86_11520 e96130ac46b5475e70120dfd5cc15ee7 175 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 3 170 1.2E-28 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 DFR86_11520 e96130ac46b5475e70120dfd5cc15ee7 175 Pfam PF01930 Domain of unknown function DUF83 4 169 2.9E-17 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 DFR86_11520 e96130ac46b5475e70120dfd5cc15ee7 175 Gene3D G3DSA:3.90.320.10 1 172 2.0E-7 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal DFR86_09005 fb34b487780a0537f13126cbbc528ff5 310 SUPERFAMILY SSF53335 150 283 1.38E-22 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_09005 fb34b487780a0537f13126cbbc528ff5 310 Pfam PF01170 Putative RNA methylase family UPF0020 140 284 6.2E-21 T 31-10-2018 IPR000241 Putative RNA methylase domain DFR86_09005 fb34b487780a0537f13126cbbc528ff5 310 Gene3D G3DSA:3.40.50.150 137 310 6.2E-30 T 31-10-2018 DFR86_09005 fb34b487780a0537f13126cbbc528ff5 310 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 229 235 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DFR86_07155 d8783d017d981175f42f42e0fbe356c2 91 SUPERFAMILY SSF54984 1 89 7.06E-24 T 31-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 DFR86_07155 d8783d017d981175f42f42e0fbe356c2 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 6 89 1.5E-17 T 31-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 DFR86_07155 d8783d017d981175f42f42e0fbe356c2 91 PIRSF PIRSF006521 1 89 2.8E-32 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 DFR86_07155 d8783d017d981175f42f42e0fbe356c2 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 41.485 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 DFR86_07155 d8783d017d981175f42f42e0fbe356c2 91 SMART SM00888 3 89 9.6E-37 T 31-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 DFR86_07155 d8783d017d981175f42f42e0fbe356c2 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 1 89 4.7E-22 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 DFR86_07155 d8783d017d981175f42f42e0fbe356c2 91 Gene3D G3DSA:3.30.70.60 1 89 9.3E-28 T 31-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 DFR86_05035 e056139d69ac95595b2a0e014c832682 471 ProSitePatterns PS00217 Sugar transport proteins signature 2. 124 149 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_05035 e056139d69ac95595b2a0e014c832682 471 ProSitePatterns PS00216 Sugar transport proteins signature 1. 313 329 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_05035 e056139d69ac95595b2a0e014c832682 471 SUPERFAMILY SSF103473 8 460 2.35E-66 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_05035 e056139d69ac95595b2a0e014c832682 471 Pfam PF00083 Sugar (and other) transporter 29 458 7.8E-49 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR86_05595 3d1ac14672c9b9810005531deaac5194 93 Gene3D G3DSA:1.10.10.10 2 82 9.8E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_05595 3d1ac14672c9b9810005531deaac5194 93 SUPERFAMILY SSF46785 6 75 8.53E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_04690 89ece329267ced0da44408570279d03f 257 PIRSF PIRSF006157 1 257 6.4E-48 T 31-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 DFR86_04690 89ece329267ced0da44408570279d03f 257 SUPERFAMILY SSF53213 5 255 4.05E-50 T 31-10-2018 DFR86_04690 89ece329267ced0da44408570279d03f 257 Gene3D G3DSA:3.40.830.10 4 254 1.7E-47 T 31-10-2018 DFR86_04690 89ece329267ced0da44408570279d03f 257 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 239 6.7E-32 T 31-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 DFR86_10335 76a1d1e9e44e149e18484138d006afec 236 SUPERFAMILY SSF100950 1 211 2.23E-34 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR86_10335 76a1d1e9e44e149e18484138d006afec 236 Gene3D G3DSA:3.40.50.10420 32 201 1.2E-15 T 31-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily DFR86_10335 76a1d1e9e44e149e18484138d006afec 236 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 194 1.0E-35 T 31-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase DFR86_02840 2cda0b4bb340687ec5b1d90f29218ac1 159 Pfam PF09821 C-terminal AAA-associated domain 31 145 2.3E-29 T 31-10-2018 IPR018632 C-terminal AAA-associated domain DFR86_06385 a452b7a1660bf73b88efcc5295c76626 182 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 31 142 3.0E-24 T 31-10-2018 DFR86_06385 a452b7a1660bf73b88efcc5295c76626 182 Gene3D G3DSA:2.40.320.10 4 182 8.6E-40 T 31-10-2018 DFR86_06385 a452b7a1660bf73b88efcc5295c76626 182 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 4 177 5.8E-42 T 31-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 DFR86_06385 a452b7a1660bf73b88efcc5295c76626 182 SMART SM01118 4 179 8.2E-20 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 DFR86_06385 a452b7a1660bf73b88efcc5295c76626 182 SUPERFAMILY SSF55154 5 177 3.11E-33 T 31-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 DFR86_06385 a452b7a1660bf73b88efcc5295c76626 182 Pfam PF01928 CYTH domain 5 165 1.6E-30 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 DFR86_01415 880142a3898ce70c037748e056bf9761 442 Gene3D G3DSA:3.40.50.300 27 185 1.3E-7 T 31-10-2018 DFR86_01415 880142a3898ce70c037748e056bf9761 442 SUPERFAMILY SSF52540 33 237 2.44E-9 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01615 36490bd571f571659d20b167f8ffc5de 639 Pfam PF13520 Amino acid permease 27 471 2.7E-38 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_01615 36490bd571f571659d20b167f8ffc5de 639 Gene3D G3DSA:1.20.1740.10 21 509 3.6E-60 T 31-10-2018 DFR86_01615 36490bd571f571659d20b167f8ffc5de 639 PIRSF PIRSF006060 8 504 3.3E-66 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_01615 36490bd571f571659d20b167f8ffc5de 639 PIRSF PIRSF006060 486 638 77.0 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_11810 c1ceb33e37aabc005071d31855e54f17 1046 Pfam PF04465 Protein of unknown function (DUF499) 75 1030 1.4E-124 T 31-10-2018 IPR007555 Protein of unknown function DUF499 DFR86_00080 c1ceb33e37aabc005071d31855e54f17 1046 Pfam PF04465 Protein of unknown function (DUF499) 75 1030 1.4E-124 T 31-10-2018 IPR007555 Protein of unknown function DUF499 DFR86_08460 53f7cca39cc378f5e55b6d4644e544b3 100 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 35 8.6E-9 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR86_08460 53f7cca39cc378f5e55b6d4644e544b3 100 SMART SM00661 2 57 3.2E-13 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR86_01450 b1cf8284c4162c0639185485cf8b32f2 427 Gene3D G3DSA:1.20.1250.20 10 426 2.5E-91 T 31-10-2018 DFR86_01450 b1cf8284c4162c0639185485cf8b32f2 427 SUPERFAMILY SSF103473 8 418 9.42E-74 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_01450 b1cf8284c4162c0639185485cf8b32f2 427 PRINTS PR00171 Sugar transporter signature 21 31 8.4E-6 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_01450 b1cf8284c4162c0639185485cf8b32f2 427 PRINTS PR00171 Sugar transporter signature 346 358 8.4E-6 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_01450 b1cf8284c4162c0639185485cf8b32f2 427 PRINTS PR00171 Sugar transporter signature 104 123 8.4E-6 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR86_01450 b1cf8284c4162c0639185485cf8b32f2 427 ProSitePatterns PS00217 Sugar transport proteins signature 2. 109 134 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_01450 b1cf8284c4162c0639185485cf8b32f2 427 Pfam PF00083 Sugar (and other) transporter 14 419 2.1E-54 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR86_01450 b1cf8284c4162c0639185485cf8b32f2 427 ProSitePatterns PS00216 Sugar transport proteins signature 1. 286 302 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_06045 f9d6fd75cb5b0887647c16740a5d726a 178 Hamap MF_00590 UPF0218 protein . 17 176 28.051 T 31-10-2018 IPR007164 Protein of unknown function DUF359 DFR86_06045 f9d6fd75cb5b0887647c16740a5d726a 178 PIRSF PIRSF006533 12 178 1.2E-52 T 31-10-2018 IPR007164 Protein of unknown function DUF359 DFR86_06045 f9d6fd75cb5b0887647c16740a5d726a 178 Pfam PF04019 Protein of unknown function (DUF359) 56 174 5.6E-35 T 31-10-2018 IPR007164 Protein of unknown function DUF359 DFR86_01520 076943cb17b236fafef96192c8b5affe 385 SUPERFAMILY SSF103473 7 364 1.09E-39 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_01520 076943cb17b236fafef96192c8b5affe 385 Gene3D G3DSA:1.20.1250.20 3 373 5.4E-37 T 31-10-2018 DFR86_01520 076943cb17b236fafef96192c8b5affe 385 Pfam PF07690 Major Facilitator Superfamily 13 330 4.0E-23 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 SUPERFAMILY SSF54631 1 56 4.59E-6 T 31-10-2018 DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 SUPERFAMILY SSF54631 206 266 3.72E-13 T 31-10-2018 DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 Gene3D G3DSA:3.10.580.10 1 133 3.8E-28 T 31-10-2018 DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 Pfam PF00571 CBS domain 9 54 4.9E-6 T 31-10-2018 IPR000644 CBS domain DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 Pfam PF00571 CBS domain 142 188 1.4E-10 T 31-10-2018 IPR000644 CBS domain DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 Pfam PF00571 CBS domain 77 127 4.2E-10 T 31-10-2018 IPR000644 CBS domain DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 Pfam PF00571 CBS domain 210 265 2.6E-11 T 31-10-2018 IPR000644 CBS domain DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 SMART SM00116 146 194 5.2E-7 T 31-10-2018 IPR000644 CBS domain DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 SMART SM00116 83 131 1.2E-6 T 31-10-2018 IPR000644 CBS domain DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 SMART SM00116 217 265 8.3E-8 T 31-10-2018 IPR000644 CBS domain DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 SMART SM00116 10 56 0.033 T 31-10-2018 IPR000644 CBS domain DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 Gene3D G3DSA:3.10.580.10 134 270 4.6E-44 T 31-10-2018 DFR86_07335 ed9578e537011225dff7d0e88b1001f1 278 SUPERFAMILY SSF54631 75 194 3.88E-30 T 31-10-2018 DFR86_04695 8321ad9393438b9cb1c0613ca0e7a44a 185 Pfam PF13847 Methyltransferase domain 35 142 4.5E-17 T 31-10-2018 IPR025714 Methyltransferase domain DFR86_04695 8321ad9393438b9cb1c0613ca0e7a44a 185 SUPERFAMILY SSF53335 24 183 7.15E-29 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_04695 8321ad9393438b9cb1c0613ca0e7a44a 185 Gene3D G3DSA:3.40.50.150 7 181 2.9E-34 T 31-10-2018 DFR86_02020 dbaf39f41731f3ccfa07753d6725ed6b 328 Gene3D G3DSA:3.50.50.60 134 302 6.7E-14 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_02020 dbaf39f41731f3ccfa07753d6725ed6b 328 SUPERFAMILY SSF51971 2 304 1.17E-12 T 31-10-2018 DFR86_02020 dbaf39f41731f3ccfa07753d6725ed6b 328 Gene3D G3DSA:3.30.9.10 173 260 6.7E-14 T 31-10-2018 DFR86_05120 1f2684da875919bed6a50411b1892cee 302 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 14 296 5.0E-92 T 31-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related DFR86_05120 1f2684da875919bed6a50411b1892cee 302 Pfam PF01040 UbiA prenyltransferase family 31 265 3.0E-39 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 DFR86_05120 1f2684da875919bed6a50411b1892cee 302 Gene3D G3DSA:1.10.357.140 21 177 9.4E-42 T 31-10-2018 DFR86_05120 1f2684da875919bed6a50411b1892cee 302 Gene3D G3DSA:1.20.120.1780 178 301 1.8E-20 T 31-10-2018 DFR86_10600 ac40ef37c68479ff59cb4adbccfd9a7a 261 SUPERFAMILY SSF74650 2 259 1.0E-53 T 31-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 DFR86_10600 ac40ef37c68479ff59cb4adbccfd9a7a 261 Pfam PF01263 Aldose 1-epimerase 2 257 2.3E-37 T 31-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 DFR86_10600 ac40ef37c68479ff59cb4adbccfd9a7a 261 Gene3D G3DSA:2.70.98.10 1 260 1.4E-50 T 31-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 DFR86_03340 b7b5aa9bed17884627f09a5142528799 454 SUPERFAMILY SSF51905 5 358 1.1E-32 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03340 b7b5aa9bed17884627f09a5142528799 454 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.4E-5 T 31-10-2018 DFR86_03340 b7b5aa9bed17884627f09a5142528799 454 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 2.4E-5 T 31-10-2018 DFR86_03340 b7b5aa9bed17884627f09a5142528799 454 Gene3D G3DSA:3.50.50.60 2 453 9.1E-169 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03340 b7b5aa9bed17884627f09a5142528799 454 Pfam PF01494 FAD binding domain 7 187 1.4E-8 T 31-10-2018 IPR002938 FAD-binding domain GO:0071949 DFR86_03340 b7b5aa9bed17884627f09a5142528799 454 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 7 316 6.5E-58 T 31-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 DFR86_10210 9618f267cfaca1d03684f2ed5cd6209e 264 Pfam PF07849 Protein of unknown function (DUF1641) 224 260 3.5E-13 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 DFR86_03855 5f837be3d45090b1ffd9dc3bfa008b2d 199 Pfam PF13520 Amino acid permease 1 185 2.3E-10 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_03855 5f837be3d45090b1ffd9dc3bfa008b2d 199 Gene3D G3DSA:1.20.1740.10 1 199 7.2E-25 T 31-10-2018 DFR86_05685 7cf4ea85ef72471078c16167189896c1 386 PIRSF PIRSF016495 9 386 7.4E-145 T 31-10-2018 IPR009995 Protein of unknown function DUF1512 DFR86_05685 7cf4ea85ef72471078c16167189896c1 386 Pfam PF07431 Protein of unknown function (DUF1512) 29 385 5.6E-143 T 31-10-2018 IPR009995 Protein of unknown function DUF1512 DFR86_07115 71435560e18149436591b8f624add022 297 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 223 239 - T 31-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07115 71435560e18149436591b8f624add022 297 PIRSF PIRSF001438 1 294 1.5E-78 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07115 71435560e18149436591b8f624add022 297 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 218 285 1.1E-8 T 31-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07115 71435560e18149436591b8f624add022 297 SUPERFAMILY SSF54782 212 291 8.11E-11 T 31-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07115 71435560e18149436591b8f624add022 297 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 204 9.8E-55 T 31-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07115 71435560e18149436591b8f624add022 297 Gene3D G3DSA:3.40.190.10 95 191 7.9E-53 T 31-10-2018 DFR86_07115 71435560e18149436591b8f624add022 297 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 287 8.9E-90 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07115 71435560e18149436591b8f624add022 297 Gene3D G3DSA:3.40.190.10 4 208 7.9E-53 T 31-10-2018 DFR86_07115 71435560e18149436591b8f624add022 297 PRINTS PR00151 Porphobilinogen deaminase signature 136 153 2.9E-22 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07115 71435560e18149436591b8f624add022 297 PRINTS PR00151 Porphobilinogen deaminase signature 71 90 2.9E-22 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07115 71435560e18149436591b8f624add022 297 PRINTS PR00151 Porphobilinogen deaminase signature 222 239 2.9E-22 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07115 71435560e18149436591b8f624add022 297 PRINTS PR00151 Porphobilinogen deaminase signature 117 134 2.9E-22 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07115 71435560e18149436591b8f624add022 297 SUPERFAMILY SSF53850 3 210 7.24E-56 T 31-10-2018 DFR86_07115 71435560e18149436591b8f624add022 297 Gene3D G3DSA:3.30.160.40 213 294 3.8E-6 T 31-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_04830 8ad1b50d05873b3951c480eca0fa1523 188 Gene3D G3DSA:3.10.590.10 18 121 2.3E-5 T 31-10-2018 DFR86_03785 f4ee4fc122405e858549204ef41b149d 432 Pfam PF03008 Archaea bacterial proteins of unknown function 300 376 2.5E-15 T 31-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal DFR86_03785 f4ee4fc122405e858549204ef41b149d 432 Pfam PF01637 ATPase domain predominantly from Archaea 8 197 8.3E-26 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR86_03785 f4ee4fc122405e858549204ef41b149d 432 Gene3D G3DSA:3.40.50.300 5 163 1.7E-26 T 31-10-2018 DFR86_03785 f4ee4fc122405e858549204ef41b149d 432 SUPERFAMILY SSF52540 6 234 1.88E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_11625 571599681b5db6a352341439f8d3ea91 282 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 2 277 2.3E-70 T 31-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 DFR86_11625 571599681b5db6a352341439f8d3ea91 282 Pfam PF03787 RAMP superfamily 5 277 3.4E-25 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_02315 bafd49dbd1006c8586b76cff5a2faed6 411 Gene3D G3DSA:3.40.718.10 1 411 7.7E-163 T 31-10-2018 DFR86_02315 bafd49dbd1006c8586b76cff5a2faed6 411 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 26 403 1.7E-104 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 DFR86_02315 bafd49dbd1006c8586b76cff5a2faed6 411 SUPERFAMILY SSF53659 3 407 1.31E-131 T 31-10-2018 DFR86_02315 bafd49dbd1006c8586b76cff5a2faed6 411 SMART SM01329 25 404 2.8E-162 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 DFR86_00160 fcb3fc93088d9bda3c613e826d0f7e7e 270 Pfam PF03787 RAMP superfamily 30 177 6.2E-10 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_00210 a10afc87ae937c3374a7e633aba226f5 241 SUPERFAMILY SSF51695 2 238 4.97E-70 T 31-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 DFR86_00210 a10afc87ae937c3374a7e633aba226f5 241 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 232 6.1E-44 T 31-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 DFR86_00210 a10afc87ae937c3374a7e633aba226f5 241 Gene3D G3DSA:3.20.20.190 1 241 6.4E-78 T 31-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 DFR86_11450 beb083b82e92323baa467780b8d2f443 54 SUPERFAMILY SSF89447 7 48 1.69E-7 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR86_11450 beb083b82e92323baa467780b8d2f443 54 Gene3D G3DSA:2.10.260.10 2 50 2.0E-10 T 31-10-2018 DFR86_11450 beb083b82e92323baa467780b8d2f443 54 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 10 54 1.1E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR86_05510 bf953cb2cdc1c58ed1b68b52ca486637 189 Gene3D G3DSA:3.90.550.10 7 185 1.8E-27 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_05510 bf953cb2cdc1c58ed1b68b52ca486637 189 SUPERFAMILY SSF53448 9 140 6.98E-20 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_05510 bf953cb2cdc1c58ed1b68b52ca486637 189 Pfam PF12804 MobA-like NTP transferase domain 9 128 9.3E-16 T 31-10-2018 IPR025877 MobA-like NTP transferase DFR86_03415 18a74c7421815fff17057a67d1a52b78 159 Pfam PF00692 dUTPase 64 145 5.6E-13 T 31-10-2018 IPR029054 dUTPase-like DFR86_03415 18a74c7421815fff17057a67d1a52b78 159 Gene3D G3DSA:2.70.40.10 1 141 2.0E-36 T 31-10-2018 IPR036157 dUTPase-like superfamily DFR86_03415 18a74c7421815fff17057a67d1a52b78 159 SUPERFAMILY SSF51283 1 155 2.88E-29 T 31-10-2018 IPR036157 dUTPase-like superfamily DFR86_05275 eddc37e353833846834804374c6d813c 307 Pfam PF03308 ArgK protein 17 275 6.3E-85 T 31-10-2018 DFR86_05275 eddc37e353833846834804374c6d813c 307 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 11 290 1.5E-90 T 31-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 DFR86_05275 eddc37e353833846834804374c6d813c 307 Gene3D G3DSA:3.40.50.300 42 246 8.4E-72 T 31-10-2018 DFR86_05275 eddc37e353833846834804374c6d813c 307 SUPERFAMILY SSF52540 1 268 1.3E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_02605 d63599a4cdaea521f40671703a6eb246 158 Gene3D G3DSA:2.60.120.630 2 144 3.8E-48 T 31-10-2018 IPR023131 Mth639-like domain superfamily DFR86_02605 d63599a4cdaea521f40671703a6eb246 158 Pfam PF04027 Domain of unknown function (DUF371) 8 137 7.0E-46 T 31-10-2018 IPR007171 Protein of unknown function DUF371 DFR86_07035 2c770039065d383cb83c5adc33bbae08 607 Pfam PF04312 Protein of unknown function (DUF460) 218 358 1.4E-46 T 31-10-2018 IPR007408 Protein of unknown function DUF460 DFR86_08495 e76b83d34b22b285d4425e31e2577f2b 97 SUPERFAMILY SSF101386 8 96 1.02E-24 T 31-10-2018 DFR86_08495 e76b83d34b22b285d4425e31e2577f2b 97 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 6 92 21.07 T 31-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 DFR86_08495 e76b83d34b22b285d4425e31e2577f2b 97 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 9 92 1.4E-28 T 31-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 DFR86_08495 e76b83d34b22b285d4425e31e2577f2b 97 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 10 95 4.5E-17 T 31-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 DFR86_08495 e76b83d34b22b285d4425e31e2577f2b 97 Gene3D G3DSA:1.10.287.1080 5 97 2.2E-28 T 31-10-2018 DFR86_06950 a8b8e7d0aab2981c7ad80ab1653e87d8 304 SUPERFAMILY SSF81301 113 175 5.45E-5 T 31-10-2018 DFR86_06950 a8b8e7d0aab2981c7ad80ab1653e87d8 304 Pfam PF01909 Nucleotidyltransferase domain 117 200 3.9E-6 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR86_00935 1c64dd6a6379edca84eaac158d3fca2b 335 Pfam PF00535 Glycosyl transferase family 2 8 113 3.0E-9 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_00935 1c64dd6a6379edca84eaac158d3fca2b 335 Gene3D G3DSA:3.90.550.10 1 270 3.7E-17 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00935 1c64dd6a6379edca84eaac158d3fca2b 335 SUPERFAMILY SSF53448 8 228 1.69E-22 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_10935 9da18c45e43720ec0fcf5d37ab1b5856 273 SUPERFAMILY SSF46785 210 269 1.13E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_10935 9da18c45e43720ec0fcf5d37ab1b5856 273 Gene3D G3DSA:1.10.10.10 210 273 2.1E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10935 9da18c45e43720ec0fcf5d37ab1b5856 273 Pfam PF09339 IclR helix-turn-helix domain 214 258 1.7E-7 T 31-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DFR86_11010 95ec81b85fc0c9713a2d78df05993233 504 Pfam PF13520 Amino acid permease 18 470 7.7E-24 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_11010 95ec81b85fc0c9713a2d78df05993233 504 PIRSF PIRSF006060 1 503 7.2E-40 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_11010 95ec81b85fc0c9713a2d78df05993233 504 Gene3D G3DSA:1.20.1740.10 13 496 2.9E-18 T 31-10-2018 DFR86_07550 0b29406206914b359c0edd20a01c41fa 313 Gene3D G3DSA:2.30.30.60 170 210 2.8E-5 T 31-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily DFR86_07550 0b29406206914b359c0edd20a01c41fa 313 SUPERFAMILY SSF50182 124 209 1.77E-11 T 31-10-2018 IPR010920 LSM domain superfamily DFR86_07550 0b29406206914b359c0edd20a01c41fa 313 Pfam PF00924 Mechanosensitive ion channel 83 275 4.6E-29 T 31-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 DFR86_11200 b42727ba6842266034b876a7f8e8c5c2 182 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 3 178 1.8E-64 T 31-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 DFR86_11200 b42727ba6842266034b876a7f8e8c5c2 182 Gene3D G3DSA:3.40.920.10 2 180 6.5E-53 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR86_11200 b42727ba6842266034b876a7f8e8c5c2 182 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 174 1.3E-36 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DFR86_11200 b42727ba6842266034b876a7f8e8c5c2 182 SUPERFAMILY SSF53323 4 180 1.96E-48 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR86_03475 a6dffdf3b63168993dddd4a32973123d 401 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 79 230 3.8E-7 T 31-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like DFR86_02160 1f5a7086416b9e1a40a0d453950c689b 410 Gene3D G3DSA:3.40.50.2000 185 380 4.6E-136 T 31-10-2018 DFR86_02160 1f5a7086416b9e1a40a0d453950c689b 410 SUPERFAMILY SSF53756 29 392 2.47E-46 T 31-10-2018 DFR86_02160 1f5a7086416b9e1a40a0d453950c689b 410 Pfam PF00534 Glycosyl transferases group 1 206 373 2.2E-21 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR86_02160 1f5a7086416b9e1a40a0d453950c689b 410 Gene3D G3DSA:3.40.50.2000 3 381 4.6E-136 T 31-10-2018 DFR86_07700 25a022c3db1e89bcfb568057e532c737 185 Hamap MF_00039 Putative adenylate kinase. 1 165 23.76 T 31-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 DFR86_07700 25a022c3db1e89bcfb568057e532c737 185 Gene3D G3DSA:3.40.50.300 1 170 4.4E-37 T 31-10-2018 DFR86_07700 25a022c3db1e89bcfb568057e532c737 185 Pfam PF13238 AAA domain 3 121 2.0E-20 T 31-10-2018 DFR86_07700 25a022c3db1e89bcfb568057e532c737 185 SUPERFAMILY SSF52540 2 154 2.92E-19 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04100 26bcd11c83244decd9ef0db202c2129c 285 Pfam PF01925 Sulfite exporter TauE/SafE 11 276 5.0E-41 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 DFR86_03165 f81c344a790842b24fc5581004f7a095 229 Gene3D G3DSA:3.90.1170.40 86 228 3.9E-29 T 31-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 DFR86_03165 f81c344a790842b24fc5581004f7a095 229 SUPERFAMILY SSF54690 104 223 1.57E-29 T 31-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 DFR86_03165 f81c344a790842b24fc5581004f7a095 229 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 4 85 3.1E-23 T 31-10-2018 IPR010038 MoaD, archaeal-type DFR86_03165 f81c344a790842b24fc5581004f7a095 229 SUPERFAMILY SSF54285 3 85 2.8E-13 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp DFR86_03165 f81c344a790842b24fc5581004f7a095 229 Pfam PF02597 ThiS family 6 85 2.6E-10 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 DFR86_03165 f81c344a790842b24fc5581004f7a095 229 Gene3D G3DSA:3.10.20.30 3 85 4.4E-15 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR86_03165 f81c344a790842b24fc5581004f7a095 229 Pfam PF02391 MoaE protein 103 202 4.6E-19 T 31-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 DFR86_08760 9b05dc667217857849bcd26422dacbbb 129 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 29 116 4.9E-7 T 31-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08760 9b05dc667217857849bcd26422dacbbb 129 Gene3D G3DSA:1.20.58.1610 2 125 4.9E-8 T 31-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_06520 5912eb81967d5bbaf102b960442c5115 196 Pfam PF00227 Proteasome subunit 6 183 2.0E-48 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_06520 5912eb81967d5bbaf102b960442c5115 196 Gene3D G3DSA:3.60.20.10 5 193 1.1E-53 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_06520 5912eb81967d5bbaf102b960442c5115 196 Hamap MF_02113_A Proteasome subunit beta [prcB]. 1 196 35.239 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 DFR86_06520 5912eb81967d5bbaf102b960442c5115 196 PRINTS PR00141 Proteasome component signature 133 144 3.9E-5 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_06520 5912eb81967d5bbaf102b960442c5115 196 PRINTS PR00141 Proteasome component signature 13 28 3.9E-5 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_06520 5912eb81967d5bbaf102b960442c5115 196 PRINTS PR00141 Proteasome component signature 169 180 3.9E-5 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_06520 5912eb81967d5bbaf102b960442c5115 196 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 9 55 - T 31-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR86_06520 5912eb81967d5bbaf102b960442c5115 196 SUPERFAMILY SSF56235 6 187 2.44E-51 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_06520 5912eb81967d5bbaf102b960442c5115 196 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 6 187 2.2E-71 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 DFR86_06880 76049166198427d76788464098df7f64 144 ProSitePatterns PS00475 Ribosomal protein L15 signature. 105 135 - T 31-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06880 76049166198427d76788464098df7f64 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 2 141 12.485 T 31-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 DFR86_06880 76049166198427d76788464098df7f64 144 Gene3D G3DSA:4.10.990.10 5 54 3.8E-7 T 31-10-2018 IPR027386 50S ribosomal protein L15, N-terminal DFR86_06880 76049166198427d76788464098df7f64 144 Gene3D G3DSA:3.100.10.10 61 144 3.2E-16 T 31-10-2018 DFR86_06880 76049166198427d76788464098df7f64 144 SUPERFAMILY SSF52080 7 141 1.1E-29 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily DFR86_06880 76049166198427d76788464098df7f64 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 30 139 1.5E-16 T 31-10-2018 IPR021131 Ribosomal protein L18e/L15P DFR86_04880 465a796a84813140e4869caa1e7d35af 392 Gene3D G3DSA:3.50.50.60 5 315 1.4E-65 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_04880 465a796a84813140e4869caa1e7d35af 392 SUPERFAMILY SSF51905 126 250 2.08E-21 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_04880 465a796a84813140e4869caa1e7d35af 392 SUPERFAMILY SSF51905 2 137 5.91E-20 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_04880 465a796a84813140e4869caa1e7d35af 392 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 131 2.7E-13 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR86_04880 465a796a84813140e4869caa1e7d35af 392 Gene3D G3DSA:3.50.50.60 117 261 1.4E-65 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_08685 2b552bacf614aedbe5d1fc457152e7a6 191 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DFR86_08685 2b552bacf614aedbe5d1fc457152e7a6 191 Gene3D G3DSA:1.20.120.1760 6 189 8.7E-44 T 31-10-2018 DFR86_08685 2b552bacf614aedbe5d1fc457152e7a6 191 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 90 6.4E-11 T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DFR86_08325 074bfb75fe7ad5c6b0ebf9b5b7a87c1c 401 Pfam PF00156 Phosphoribosyl transferase domain 222 329 1.3E-8 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR86_08325 074bfb75fe7ad5c6b0ebf9b5b7a87c1c 401 Gene3D G3DSA:3.60.20.10 106 398 4.3E-81 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_08325 074bfb75fe7ad5c6b0ebf9b5b7a87c1c 401 SUPERFAMILY SSF53271 194 398 9.83E-52 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR86_08325 074bfb75fe7ad5c6b0ebf9b5b7a87c1c 401 PIRSF PIRSF000485 1 75 3.9E-4 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 DFR86_08325 074bfb75fe7ad5c6b0ebf9b5b7a87c1c 401 PIRSF PIRSF000485 76 401 1.8E-98 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 DFR86_08325 074bfb75fe7ad5c6b0ebf9b5b7a87c1c 401 Gene3D G3DSA:3.40.50.2020 218 382 4.3E-81 T 31-10-2018 DFR86_08325 074bfb75fe7ad5c6b0ebf9b5b7a87c1c 401 SUPERFAMILY SSF56235 3 200 1.9E-15 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_09230 50d5e4a65796f7b8059ab4111b6c5445 146 SUPERFAMILY SSF46579 11 140 1.07E-15 T 31-10-2018 DFR86_09230 50d5e4a65796f7b8059ab4111b6c5445 146 Pfam PF02996 Prefoldin subunit 22 140 5.8E-18 T 31-10-2018 IPR004127 Prefoldin alpha-like DFR86_09230 50d5e4a65796f7b8059ab4111b6c5445 146 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 12 140 5.1E-21 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 DFR86_09230 50d5e4a65796f7b8059ab4111b6c5445 146 Gene3D G3DSA:1.10.287.370 2 145 6.7E-14 T 31-10-2018 IPR009053 Prefoldin DFR86_09230 50d5e4a65796f7b8059ab4111b6c5445 146 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 3 140 12.853 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 DFR86_10165 c7ac9c0e02ff958c186557218d72f9d0 317 Pfam PF08544 GHMP kinases C terminal 240 300 5.1E-6 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain DFR86_10165 c7ac9c0e02ff958c186557218d72f9d0 317 Gene3D G3DSA:3.30.230.10 1 169 1.8E-25 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR86_10165 c7ac9c0e02ff958c186557218d72f9d0 317 SUPERFAMILY SSF54211 2 187 1.29E-33 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_10165 c7ac9c0e02ff958c186557218d72f9d0 317 Gene3D G3DSA:3.30.70.890 172 306 9.9E-15 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR86_10165 c7ac9c0e02ff958c186557218d72f9d0 317 Pfam PF00288 GHMP kinases N terminal domain 91 149 3.4E-13 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR86_10165 c7ac9c0e02ff958c186557218d72f9d0 317 PRINTS PR00960 LmbP protein signature 87 108 6.0E-5 T 31-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 DFR86_10165 c7ac9c0e02ff958c186557218d72f9d0 317 PRINTS PR00960 LmbP protein signature 265 284 6.0E-5 T 31-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 DFR86_10165 c7ac9c0e02ff958c186557218d72f9d0 317 SUPERFAMILY SSF55060 173 306 4.56E-17 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR86_08045 af3e9211078936ecfd8cc2e44fad600a 275 Pfam PF07282 Putative transposase DNA-binding domain 205 269 2.3E-20 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_01255 3c3b4e3916e2e101defda99272400212 282 SUPERFAMILY SSF48179 159 281 6.01E-28 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR86_01255 3c3b4e3916e2e101defda99272400212 282 Gene3D G3DSA:3.40.50.720 1 159 4.6E-36 T 31-10-2018 DFR86_01255 3c3b4e3916e2e101defda99272400212 282 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 160 280 2.8E-21 T 31-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DFR86_01255 3c3b4e3916e2e101defda99272400212 282 SUPERFAMILY SSF51735 2 158 4.6E-34 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_01255 3c3b4e3916e2e101defda99272400212 282 PIRSF PIRSF000103 1 282 1.0E-59 T 31-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 DFR86_01255 3c3b4e3916e2e101defda99272400212 282 Gene3D G3DSA:1.10.1040.10 160 282 1.9E-28 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR86_01255 3c3b4e3916e2e101defda99272400212 282 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 157 5.2E-31 T 31-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 DFR86_02890 0aff35d4a618d8307d5a53b2903974d6 241 Gene3D G3DSA:3.40.190.10 101 202 3.5E-7 T 31-10-2018 DFR86_02890 0aff35d4a618d8307d5a53b2903974d6 241 SUPERFAMILY SSF53850 23 237 3.52E-13 T 31-10-2018 DFR86_02890 0aff35d4a618d8307d5a53b2903974d6 241 Gene3D G3DSA:3.40.190.10 93 237 3.5E-7 T 31-10-2018 DFR86_02890 0aff35d4a618d8307d5a53b2903974d6 241 Pfam PF13531 Bacterial extracellular solute-binding protein 92 237 7.7E-7 T 31-10-2018 DFR86_04055 0d3f15374acf83a6813a8b7c746cd23b 456 Pfam PF00037 4Fe-4S binding domain 144 166 1.9E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_04055 0d3f15374acf83a6813a8b7c746cd23b 456 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 335 346 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_04055 0d3f15374acf83a6813a8b7c746cd23b 456 Gene3D G3DSA:3.30.70.20 104 183 1.1E-12 T 31-10-2018 DFR86_04055 0d3f15374acf83a6813a8b7c746cd23b 456 SUPERFAMILY SSF54862 81 352 1.18E-27 T 31-10-2018 DFR86_04055 0d3f15374acf83a6813a8b7c746cd23b 456 Gene3D G3DSA:3.30.70.20 291 359 1.2E-11 T 31-10-2018 DFR86_04055 0d3f15374acf83a6813a8b7c746cd23b 456 Pfam PF12838 4Fe-4S dicluster domain 301 347 3.6E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR86_04055 0d3f15374acf83a6813a8b7c746cd23b 456 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 150 161 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_09600 6fd34511d2238e24c166e87939ed8233 205 Pfam PF13263 PHP-associated 128 180 6.5E-15 T 31-10-2018 DFR86_09600 6fd34511d2238e24c166e87939ed8233 205 SUPERFAMILY SSF89550 1 183 4.71E-40 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 DFR86_09600 6fd34511d2238e24c166e87939ed8233 205 SMART SM00481 3 61 7.8E-14 T 31-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal DFR86_09600 6fd34511d2238e24c166e87939ed8233 205 Gene3D G3DSA:3.20.20.140 1 178 9.0E-38 T 31-10-2018 DFR86_07135 b25c8740b5ce5d9894434f7af7e2a15a 230 SUPERFAMILY SSF75615 128 227 2.09E-8 T 31-10-2018 DFR86_07135 b25c8740b5ce5d9894434f7af7e2a15a 230 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 18 223 9.5E-21 T 31-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR86_07135 b25c8740b5ce5d9894434f7af7e2a15a 230 Pfam PF13241 Putative NAD(P)-binding 20 128 2.5E-24 T 31-10-2018 DFR86_07135 b25c8740b5ce5d9894434f7af7e2a15a 230 Gene3D G3DSA:3.40.50.720 17 144 2.0E-31 T 31-10-2018 DFR86_07135 b25c8740b5ce5d9894434f7af7e2a15a 230 SUPERFAMILY SSF51735 17 126 3.0E-21 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_03345 b7b5bd8fdf1040e69161ce9b334ef8c2 128 Gene3D G3DSA:3.40.50.11100 6 128 3.3E-50 T 31-10-2018 DFR86_11030 6dea779e06975bd877a326abfb85d1fa 183 Pfam PF04173 TQO small subunit DoxD 10 169 3.9E-51 T 31-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 DFR86_03250 3a8296593f8526b9f8140e9a927d374b 179 SUPERFAMILY SSF52980 31 87 1.05E-6 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR86_11165 10cb8c5279310b17c0194e7a929f7ecc 155 SUPERFAMILY SSF52833 1 154 7.16E-56 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_11165 10cb8c5279310b17c0194e7a929f7ecc 155 Pfam PF00578 AhpC/TSA family 4 132 1.1E-42 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_11165 10cb8c5279310b17c0194e7a929f7ecc 155 PIRSF PIRSF000239 1 154 3.2E-30 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_11165 10cb8c5279310b17c0194e7a929f7ecc 155 Gene3D G3DSA:3.40.30.10 1 152 3.2E-57 T 31-10-2018 DFR86_00245 f2a5cdb21544b7a9511d1cf684258f52 219 Pfam PF02040 Arsenical pump membrane protein 3 218 4.7E-42 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR86_00245 f2a5cdb21544b7a9511d1cf684258f52 219 PRINTS PR00758 Arsenical pump membrane protein signature 76 100 8.0E-29 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR86_00245 f2a5cdb21544b7a9511d1cf684258f52 219 PRINTS PR00758 Arsenical pump membrane protein signature 121 143 8.0E-29 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR86_00245 f2a5cdb21544b7a9511d1cf684258f52 219 PRINTS PR00758 Arsenical pump membrane protein signature 192 216 8.0E-29 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR86_00245 f2a5cdb21544b7a9511d1cf684258f52 219 PRINTS PR00758 Arsenical pump membrane protein signature 15 40 8.0E-29 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR86_02410 9fbfc02990e42bc6532a94e81a24beb7 170 SUPERFAMILY SSF55811 3 163 4.74E-46 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 DFR86_02410 9fbfc02990e42bc6532a94e81a24beb7 170 Gene3D G3DSA:3.90.79.10 1 167 4.0E-51 T 31-10-2018 DFR86_02410 9fbfc02990e42bc6532a94e81a24beb7 170 ProSitePatterns PS00893 Nudix box signature. 66 87 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DFR86_02410 9fbfc02990e42bc6532a94e81a24beb7 170 Pfam PF00293 NUDIX domain 32 142 6.0E-15 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 DFR86_04530 e2da8d892db0ceba5078d90b51f5fc98 316 SMART SM00382 30 218 1.2E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_04530 e2da8d892db0ceba5078d90b51f5fc98 316 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 227 292 1.5E-14 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_04530 e2da8d892db0ceba5078d90b51f5fc98 316 SUPERFAMILY SSF52540 1 247 7.77E-64 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04530 e2da8d892db0ceba5078d90b51f5fc98 316 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_04530 e2da8d892db0ceba5078d90b51f5fc98 316 Pfam PF00005 ABC transporter 22 175 7.5E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_04530 e2da8d892db0ceba5078d90b51f5fc98 316 Gene3D G3DSA:3.40.50.300 1 315 3.1E-87 T 31-10-2018 DFR86_04530 e2da8d892db0ceba5078d90b51f5fc98 316 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 226 312 1.1E-20 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_04935 df534b01184882e1ac3d784f600c99fe 374 SUPERFAMILY SSF103473 7 369 2.75E-37 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_04935 df534b01184882e1ac3d784f600c99fe 374 Gene3D G3DSA:1.20.1250.20 6 178 1.0E-18 T 31-10-2018 DFR86_04935 df534b01184882e1ac3d784f600c99fe 374 Pfam PF07690 Major Facilitator Superfamily 9 330 1.4E-27 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_04935 df534b01184882e1ac3d784f600c99fe 374 Gene3D G3DSA:1.20.1250.20 179 374 5.9E-10 T 31-10-2018 DFR86_03815 2943fc4b69e1da5cfd12c871b211cf87 109 Pfam PF01638 HxlR-like helix-turn-helix 24 105 1.4E-23 T 31-10-2018 IPR002577 Helix-turn-helix, HxlR type DFR86_03815 2943fc4b69e1da5cfd12c871b211cf87 109 Gene3D G3DSA:1.10.10.10 3 108 1.1E-30 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_03815 2943fc4b69e1da5cfd12c871b211cf87 109 SUPERFAMILY SSF46785 8 108 2.61E-30 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_01305 b324f08a751d30efe18264cccf09e570 326 Gene3D G3DSA:2.102.10.10 86 296 1.3E-54 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_01305 b324f08a751d30efe18264cccf09e570 326 Pfam PF00355 Rieske [2Fe-2S] domain 148 250 1.9E-8 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR86_01305 b324f08a751d30efe18264cccf09e570 326 SUPERFAMILY SSF50022 90 278 1.71E-29 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_04920 afcf3d5e9b572d2a1043e0ec9fdd9831 291 Pfam PF00892 EamA-like transporter family 4 126 8.7E-14 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR86_04920 afcf3d5e9b572d2a1043e0ec9fdd9831 291 Pfam PF00892 EamA-like transporter family 137 266 2.3E-16 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR86_04920 afcf3d5e9b572d2a1043e0ec9fdd9831 291 SUPERFAMILY SSF103481 59 127 7.06E-10 T 31-10-2018 DFR86_04920 afcf3d5e9b572d2a1043e0ec9fdd9831 291 SUPERFAMILY SSF103481 171 271 1.31E-8 T 31-10-2018 DFR86_08125 d2947b21b0e143099e0749f3b2141094 268 SUPERFAMILY SSF51569 3 256 7.69E-59 T 31-10-2018 DFR86_08125 d2947b21b0e143099e0749f3b2141094 268 Pfam PF01791 DeoC/LacD family aldolase 19 241 1.1E-33 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 DFR86_08125 d2947b21b0e143099e0749f3b2141094 268 PIRSF PIRSF038992 1 267 9.3E-77 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 DFR86_08125 d2947b21b0e143099e0749f3b2141094 268 SMART SM01133 17 242 1.1E-24 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 DFR86_08125 d2947b21b0e143099e0749f3b2141094 268 Gene3D G3DSA:3.20.20.70 1 266 4.1E-70 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_07465 3059f50c4749e59c5e3b34f8828d1979 238 Gene3D G3DSA:3.40.1080.10 2 235 5.9E-37 T 31-10-2018 DFR86_07465 3059f50c4749e59c5e3b34f8828d1979 238 SUPERFAMILY SSF100950 3 235 8.37E-43 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR86_07465 3059f50c4749e59c5e3b34f8828d1979 238 Pfam PF01144 Coenzyme A transferase 4 201 4.7E-30 T 31-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 DFR86_07465 3059f50c4749e59c5e3b34f8828d1979 238 SMART SM00882 3 201 0.0017 T 31-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 DFR86_01360 7438081627b81e107ff55b1f8294126b 153 Pfam PF09941 Uncharacterized conserved protein (DUF2173) 29 85 4.2E-6 T 31-10-2018 IPR018685 Protein of unknown function DUF2173 DFR86_04250 21000287d93db074a1dfa9a2496bf5c6 263 SUPERFAMILY SSF56317 1 259 6.67E-64 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR86_04250 21000287d93db074a1dfa9a2496bf5c6 263 Gene3D G3DSA:3.60.110.10 1 262 7.0E-71 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR86_04250 21000287d93db074a1dfa9a2496bf5c6 263 Pfam PF00795 Carbon-nitrogen hydrolase 2 248 8.6E-47 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 DFR86_05260 ab8240314a0efcd767f8f377f9159fde 136 Gene3D G3DSA:1.10.10.10 5 70 4.7E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_05260 ab8240314a0efcd767f8f377f9159fde 136 SUPERFAMILY SSF46785 6 78 8.04E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_05260 ab8240314a0efcd767f8f377f9159fde 136 Pfam PF12840 Helix-turn-helix domain 6 60 7.9E-7 T 31-10-2018 DFR86_06160 df718f86c7b7e9d17ae4d279790e8d5c 910 Pfam PF08494 DEAD/H associated 584 752 6.4E-15 T 31-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 DFR86_06160 df718f86c7b7e9d17ae4d279790e8d5c 910 Gene3D G3DSA:3.40.50.300 1 210 2.3E-48 T 31-10-2018 DFR86_06160 df718f86c7b7e9d17ae4d279790e8d5c 910 Pfam PF00271 Helicase conserved C-terminal domain 245 347 4.6E-18 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_06160 df718f86c7b7e9d17ae4d279790e8d5c 910 PIRSF PIRSF037307 1 910 1.2E-290 T 31-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 DFR86_06160 df718f86c7b7e9d17ae4d279790e8d5c 910 Pfam PF00270 DEAD/DEAH box helicase 21 187 2.7E-32 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR86_06160 df718f86c7b7e9d17ae4d279790e8d5c 910 SMART SM00490 268 347 8.6E-16 T 31-10-2018 IPR001650 Helicase, C-terminal DFR86_06160 df718f86c7b7e9d17ae4d279790e8d5c 910 SMART SM00487 16 218 9.0E-43 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR86_06160 df718f86c7b7e9d17ae4d279790e8d5c 910 Gene3D G3DSA:3.40.50.300 214 391 4.9E-27 T 31-10-2018 DFR86_06160 df718f86c7b7e9d17ae4d279790e8d5c 910 SUPERFAMILY SSF52540 67 362 3.2E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03770 ed47faf29dde799eb6417cb37b31cf8c 346 Gene3D G3DSA:1.20.1250.20 165 346 4.2E-13 T 31-10-2018 DFR86_03770 ed47faf29dde799eb6417cb37b31cf8c 346 Gene3D G3DSA:1.20.1250.20 1 164 2.9E-17 T 31-10-2018 DFR86_03770 ed47faf29dde799eb6417cb37b31cf8c 346 SUPERFAMILY SSF103473 3 343 1.44E-34 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_03770 ed47faf29dde799eb6417cb37b31cf8c 346 Pfam PF07690 Major Facilitator Superfamily 4 313 1.6E-25 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_00065 9ca44cacc84e37e32913d1cc317daa65 78 Pfam PF07282 Putative transposase DNA-binding domain 3 52 1.8E-14 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_11795 9ca44cacc84e37e32913d1cc317daa65 78 Pfam PF07282 Putative transposase DNA-binding domain 3 52 1.8E-14 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_05630 5e503299afece544bba10bdc4e844903 232 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 3 226 2.2E-76 T 31-10-2018 IPR018693 Protein of unknown function DUF2192 DFR86_03395 9986919e228aeb2f5120544dc761032f 207 Pfam PF00156 Phosphoribosyl transferase domain 18 142 7.1E-16 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR86_03395 9986919e228aeb2f5120544dc761032f 207 SUPERFAMILY SSF53271 9 161 1.7E-32 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR86_03395 9986919e228aeb2f5120544dc761032f 207 Gene3D G3DSA:3.40.50.2020 4 183 1.0E-36 T 31-10-2018 DFR86_07760 04694e40803613aaddfab128da4a3b5e 177 Pfam PF04967 HTH DNA binding domain 117 168 8.4E-21 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR86_05735 50f0e3a7e991709109252361aaacc7dd 326 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 92 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site DFR86_05735 50f0e3a7e991709109252361aaacc7dd 326 Gene3D G3DSA:1.10.600.10 2 326 1.4E-97 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR86_05735 50f0e3a7e991709109252361aaacc7dd 326 Pfam PF00348 Polyprenyl synthetase 27 274 4.4E-71 T 31-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 DFR86_05735 50f0e3a7e991709109252361aaacc7dd 326 SUPERFAMILY SSF48576 3 325 3.52E-91 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR86_05735 50f0e3a7e991709109252361aaacc7dd 326 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 207 219 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site DFR86_11720 bf41863a486d6d0233025aa4682e4957 592 Pfam PF09369 Domain of unknown function (DUF1998) 474 570 8.3E-10 T 31-10-2018 IPR018973 DEAD/DEAH-box helicase, putative DFR86_03185 1819f48998bce336906edfc264fbbbfe 430 Pfam PF13641 Glycosyltransferase like family 2 49 271 3.3E-20 T 31-10-2018 DFR86_03185 1819f48998bce336906edfc264fbbbfe 430 Gene3D G3DSA:3.90.550.10 39 255 1.5E-30 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_03185 1819f48998bce336906edfc264fbbbfe 430 SUPERFAMILY SSF53448 43 310 5.53E-38 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_06450 6da8ddfacf9952c0180a4b6d9de00fb1 95 Pfam PF05129 Transcription elongation factor Elf1 like 3 73 6.8E-19 T 31-10-2018 IPR007808 Transcription elongation factor 1 DFR86_06450 6da8ddfacf9952c0180a4b6d9de00fb1 95 SUPERFAMILY SSF57783 1 78 6.63E-19 T 31-10-2018 DFR86_00275 53781c5b7c77260de22f94875013d50a 112 Pfam PF04343 Protein of unknown function, DUF488 3 108 2.9E-27 T 31-10-2018 IPR007438 Protein of unknown function DUF488 DFR86_07785 60795621598e63fd5ea7b4cc0d61f448 393 Pfam PF07690 Major Facilitator Superfamily 213 376 3.0E-12 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_07785 60795621598e63fd5ea7b4cc0d61f448 393 Pfam PF07690 Major Facilitator Superfamily 17 196 1.7E-23 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR86_07785 60795621598e63fd5ea7b4cc0d61f448 393 SUPERFAMILY SSF103473 8 381 1.29E-59 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_07785 60795621598e63fd5ea7b4cc0d61f448 393 ProSitePatterns PS00217 Sugar transport proteins signature 2. 103 128 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_07785 60795621598e63fd5ea7b4cc0d61f448 393 Gene3D G3DSA:1.20.1250.20 5 390 2.2E-54 T 31-10-2018 DFR86_09760 670db1213230c5c3d86873c1f91bbf36 66 Gene3D G3DSA:2.30.30.860 1 66 3.1E-24 T 31-10-2018 DFR86_03025 936eade6ee78e6cc8eec7b498e1f8f10 552 Gene3D G3DSA:3.20.20.240 1 552 1.8E-234 T 31-10-2018 DFR86_03025 936eade6ee78e6cc8eec7b498e1f8f10 552 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 29 551 2.3E-228 T 31-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 DFR86_03025 936eade6ee78e6cc8eec7b498e1f8f10 552 Pfam PF01642 Methylmalonyl-CoA mutase 31 544 3.5E-212 T 31-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 DFR86_03025 936eade6ee78e6cc8eec7b498e1f8f10 552 SUPERFAMILY SSF51703 7 546 3.34E-204 T 31-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 DFR86_10245 9462da7afad5a4a5f26b9b9a8675382f 209 Pfam PF14947 Winged helix-turn-helix 143 201 2.8E-7 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain DFR86_10245 9462da7afad5a4a5f26b9b9a8675382f 209 Gene3D G3DSA:1.10.10.10 139 208 1.0E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10245 9462da7afad5a4a5f26b9b9a8675382f 209 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 3 192 4.5E-19 T 31-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 DFR86_10245 9462da7afad5a4a5f26b9b9a8675382f 209 SUPERFAMILY SSF46785 142 201 2.49E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_10245 9462da7afad5a4a5f26b9b9a8675382f 209 Gene3D G3DSA:3.40.50.11700 2 136 6.9E-13 T 31-10-2018 DFR86_03110 09a291edf4619167099fa3746811b4ad 58 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 40 2.1E-8 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR86_03110 09a291edf4619167099fa3746811b4ad 58 SUPERFAMILY SSF47598 1 42 1.06E-6 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR86_03110 09a291edf4619167099fa3746811b4ad 58 Gene3D G3DSA:1.10.1220.10 9 42 3.5E-5 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DFR86_02745 12af2a4aa75e3d067f8a24027d189d22 619 SUPERFAMILY SSF48208 238 614 1.59E-103 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR86_02745 12af2a4aa75e3d067f8a24027d189d22 619 Pfam PF00723 Glycosyl hydrolases family 15 271 558 4.7E-13 T 31-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 DFR86_02745 12af2a4aa75e3d067f8a24027d189d22 619 Gene3D G3DSA:1.50.10.10 255 619 1.8E-85 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR86_07580 4374e37aea4b9913aac4b62b803f163c 191 Gene3D G3DSA:3.40.50.720 36 171 4.0E-20 T 31-10-2018 DFR86_07580 4374e37aea4b9913aac4b62b803f163c 191 Pfam PF13478 XdhC Rossmann domain 39 166 8.4E-21 T 31-10-2018 IPR027051 XdhC Rossmann domain DFR86_11785 b5fce27f5ca8acbda1eb4ece767e52ea 109 Pfam PF00355 Rieske [2Fe-2S] domain 3 95 7.9E-14 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR86_11785 b5fce27f5ca8acbda1eb4ece767e52ea 109 Gene3D G3DSA:2.102.10.10 1 109 2.4E-19 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_11785 b5fce27f5ca8acbda1eb4ece767e52ea 109 SUPERFAMILY SSF50022 1 107 1.57E-20 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_00055 b5fce27f5ca8acbda1eb4ece767e52ea 109 Pfam PF00355 Rieske [2Fe-2S] domain 3 95 7.9E-14 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR86_00055 b5fce27f5ca8acbda1eb4ece767e52ea 109 Gene3D G3DSA:2.102.10.10 1 109 2.4E-19 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_00055 b5fce27f5ca8acbda1eb4ece767e52ea 109 SUPERFAMILY SSF50022 1 107 1.57E-20 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR86_08355 ad193f80672c1a624d78cf812afecdde 112 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 2 112 1.3E-37 T 31-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR86_08355 ad193f80672c1a624d78cf812afecdde 112 SUPERFAMILY SSF50249 2 111 4.65E-28 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR86_08355 ad193f80672c1a624d78cf812afecdde 112 Gene3D G3DSA:2.40.50.140 1 112 1.2E-33 T 31-10-2018 DFR86_08355 ad193f80672c1a624d78cf812afecdde 112 Pfam PF01588 Putative tRNA binding domain 13 110 1.5E-26 T 31-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 DFR86_03515 adb467445d3fac8e7edf15a2f61261f3 199 Pfam PF00174 Oxidoreductase molybdopterin binding domain 23 168 1.7E-37 T 31-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 DFR86_03515 adb467445d3fac8e7edf15a2f61261f3 199 Gene3D G3DSA:3.90.420.10 4 193 5.6E-51 T 31-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 DFR86_03515 adb467445d3fac8e7edf15a2f61261f3 199 SUPERFAMILY SSF56524 6 187 4.05E-62 T 31-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 DFR86_03575 59740266571a7d71e11970e44f743e7e 316 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 91 5.1E-10 T 31-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 DFR86_03575 59740266571a7d71e11970e44f743e7e 316 SUPERFAMILY SSF51735 1 258 1.05E-22 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_03575 59740266571a7d71e11970e44f743e7e 316 Gene3D G3DSA:3.40.50.720 2 300 8.4E-22 T 31-10-2018 DFR86_03230 aa9962d2304167c9be5c177f730ac5be 395 Pfam PF00108 Thiolase, N-terminal domain 4 262 3.3E-88 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR86_03230 aa9962d2304167c9be5c177f730ac5be 395 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 31-10-2018 IPR020613 Thiolase, conserved site GO:0016747 DFR86_03230 aa9962d2304167c9be5c177f730ac5be 395 PIRSF PIRSF000429 1 393 1.8E-122 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR86_03230 aa9962d2304167c9be5c177f730ac5be 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 1.5E-137 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR86_03230 aa9962d2304167c9be5c177f730ac5be 395 Gene3D G3DSA:3.40.47.10 126 389 1.0E-138 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_03230 aa9962d2304167c9be5c177f730ac5be 395 SUPERFAMILY SSF53901 3 268 7.52E-81 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_03230 aa9962d2304167c9be5c177f730ac5be 395 SUPERFAMILY SSF53901 270 391 1.24E-35 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_03230 aa9962d2304167c9be5c177f730ac5be 395 Gene3D G3DSA:3.40.47.10 5 275 1.0E-138 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_03230 aa9962d2304167c9be5c177f730ac5be 395 Pfam PF02803 Thiolase, C-terminal domain 270 390 1.3E-36 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 DFR86_10730 28e02365660fd7c2dc86ca513581b4d0 269 Pfam PF07849 Protein of unknown function (DUF1641) 228 265 4.6E-12 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 DFR86_09025 a5580ecb205164ea218307560f0e11f3 183 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 181 25.334 T 31-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 DFR86_09025 a5580ecb205164ea218307560f0e11f3 183 Pfam PF02834 LigT like Phosphoesterase 16 87 2.2E-15 T 31-10-2018 IPR014051 Phosphoesterase, HXTX DFR86_09025 a5580ecb205164ea218307560f0e11f3 183 Pfam PF02834 LigT like Phosphoesterase 92 173 2.0E-11 T 31-10-2018 IPR014051 Phosphoesterase, HXTX DFR86_09025 a5580ecb205164ea218307560f0e11f3 183 Gene3D G3DSA:3.90.1140.10 1 180 1.3E-48 T 31-10-2018 DFR86_09025 a5580ecb205164ea218307560f0e11f3 183 SUPERFAMILY SSF55144 1 176 8.89E-39 T 31-10-2018 IPR009097 Cyclic phosphodiesterase DFR86_09025 a5580ecb205164ea218307560f0e11f3 183 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 176 8.5E-44 T 31-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 DFR86_07770 b1d46877bab34bcd66e34e7cd07794c0 106 SUPERFAMILY SSF50346 7 70 5.1E-6 T 31-10-2018 IPR011033 PRC-barrel-like superfamily DFR86_07770 b1d46877bab34bcd66e34e7cd07794c0 106 Gene3D G3DSA:2.20.28.70 60 103 3.1E-5 T 31-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR86_07770 b1d46877bab34bcd66e34e7cd07794c0 106 Pfam PF13240 zinc-ribbon domain 81 102 4.0E-7 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR86_07770 b1d46877bab34bcd66e34e7cd07794c0 106 Pfam PF05239 PRC-barrel domain 7 69 2.6E-5 T 31-10-2018 IPR027275 PRC-barrel domain DFR86_07110 903eebba714704bf8d1e55487f55e8ee 222 Gene3D G3DSA:3.40.50.10090 120 220 1.5E-11 T 31-10-2018 DFR86_07110 903eebba714704bf8d1e55487f55e8ee 222 Gene3D G3DSA:3.40.50.10090 21 108 2.3E-10 T 31-10-2018 DFR86_07110 903eebba714704bf8d1e55487f55e8ee 222 Pfam PF02602 Uroporphyrinogen-III synthase HemD 18 213 1.3E-20 T 31-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07110 903eebba714704bf8d1e55487f55e8ee 222 SUPERFAMILY SSF69618 1 218 6.15E-30 T 31-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR86_07315 12e5873ded36332ee5473629c0f162bf 257 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 202 219 - T 31-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 DFR86_07315 12e5873ded36332ee5473629c0f162bf 257 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 26 256 8.9E-70 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 DFR86_07315 12e5873ded36332ee5473629c0f162bf 257 Pfam PF01255 Putative undecaprenyl diphosphate synthase 33 256 1.2E-67 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 DFR86_07315 12e5873ded36332ee5473629c0f162bf 257 Gene3D G3DSA:3.40.1180.10 12 257 6.9E-83 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 DFR86_07315 12e5873ded36332ee5473629c0f162bf 257 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 26 257 35.478 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 DFR86_07315 12e5873ded36332ee5473629c0f162bf 257 SUPERFAMILY SSF64005 23 252 7.06E-70 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 DFR86_05520 3f958590dd4bb2210281d49ddb8c4b66 222 Gene3D G3DSA:3.90.1490.10 126 222 2.0E-23 T 31-10-2018 DFR86_05520 3f958590dd4bb2210281d49ddb8c4b66 222 PIRSF PIRSF039123 1 222 8.5E-72 T 31-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR86_05520 3f958590dd4bb2210281d49ddb8c4b66 222 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 220 7.0E-63 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR86_05520 3f958590dd4bb2210281d49ddb8c4b66 222 Pfam PF01902 Diphthamide synthase 1 221 3.6E-63 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR86_05520 3f958590dd4bb2210281d49ddb8c4b66 222 SUPERFAMILY SSF52402 1 220 2.72E-67 T 31-10-2018 DFR86_05520 3f958590dd4bb2210281d49ddb8c4b66 222 Gene3D G3DSA:3.40.50.620 1 125 6.3E-38 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_05520 3f958590dd4bb2210281d49ddb8c4b66 222 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 220 1.7E-80 T 31-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding DFR86_06920 d2279c418f71b7ccb2302f8bb7c5ec1d 138 SUPERFAMILY SSF69819 2 138 3.79E-42 T 31-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 DFR86_06920 d2279c418f71b7ccb2302f8bb7c5ec1d 138 Gene3D G3DSA:3.55.10.10 1 138 5.4E-45 T 31-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 DFR86_06920 d2279c418f71b7ccb2302f8bb7c5ec1d 138 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 127 7.0E-41 T 31-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 DFR86_06920 d2279c418f71b7ccb2302f8bb7c5ec1d 138 Hamap MF_01222 Protein archease. 2 138 38.223 T 31-10-2018 IPR022952 Archease, archaea DFR86_06920 d2279c418f71b7ccb2302f8bb7c5ec1d 138 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 138 1.3E-39 T 31-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 DFR86_02980 daabcb4709fb77be8f9c95884782989a 278 SUPERFAMILY SSF55447 172 278 2.49E-31 T 31-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily DFR86_02980 daabcb4709fb77be8f9c95884782989a 278 SUPERFAMILY SSF56176 3 168 2.24E-48 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_02980 daabcb4709fb77be8f9c95884782989a 278 Gene3D G3DSA:3.30.390.50 173 278 7.2E-35 T 31-10-2018 DFR86_02980 daabcb4709fb77be8f9c95884782989a 278 SMART SM01092 174 275 6.3E-30 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR86_02980 daabcb4709fb77be8f9c95884782989a 278 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 175 275 3.7E-25 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR86_02980 daabcb4709fb77be8f9c95884782989a 278 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 168 6.9E-49 T 31-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DFR86_02980 daabcb4709fb77be8f9c95884782989a 278 Gene3D G3DSA:3.30.465.10 59 167 4.7E-36 T 31-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 DFR86_02980 daabcb4709fb77be8f9c95884782989a 278 Gene3D G3DSA:3.30.43.10 1 53 9.1E-22 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR86_10105 f349f9dfb980997778cbf3fa0f8c98a7 228 Pfam PF00483 Nucleotidyl transferase 2 219 1.2E-31 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR86_10105 f349f9dfb980997778cbf3fa0f8c98a7 228 Gene3D G3DSA:3.90.550.10 1 224 1.5E-63 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_10105 f349f9dfb980997778cbf3fa0f8c98a7 228 SUPERFAMILY SSF53448 1 225 3.13E-60 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_08745 e46e5b3ecd1d3997057dbc9d6d9a163e 351 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 237 250 - T 31-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08745 e46e5b3ecd1d3997057dbc9d6d9a163e 351 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 10 350 18.038 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08745 e46e5b3ecd1d3997057dbc9d6d9a163e 351 Pfam PF00146 NADH dehydrogenase 26 342 2.0E-77 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08860 1c5598cbcf487d1ce852c2df3f829618 330 Gene3D G3DSA:3.20.20.70 52 322 4.2E-101 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_08860 1c5598cbcf487d1ce852c2df3f829618 330 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 64 321 7.5E-129 T 31-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 DFR86_08860 1c5598cbcf487d1ce852c2df3f829618 330 Pfam PF00793 DAHP synthetase I family 78 315 6.6E-73 T 31-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 DFR86_08860 1c5598cbcf487d1ce852c2df3f829618 330 SUPERFAMILY SSF51569 50 328 1.37E-98 T 31-10-2018 DFR86_06745 ca3ad3cea8f9af8c0b1edc790a0d35fc 470 SUPERFAMILY SSF53187 9 335 5.69E-19 T 31-10-2018 DFR86_06745 ca3ad3cea8f9af8c0b1edc790a0d35fc 470 Pfam PF04389 Peptidase family M28 183 335 2.8E-11 T 31-10-2018 IPR007484 Peptidase M28 DFR86_06745 ca3ad3cea8f9af8c0b1edc790a0d35fc 470 Gene3D G3DSA:3.40.630.10 153 350 7.2E-19 T 31-10-2018 DFR86_10745 d85f262e6834f1032e70f4c053899bd2 133 Pfam PF02635 DsrE/DsrF-like family 15 133 1.9E-22 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR86_10745 d85f262e6834f1032e70f4c053899bd2 133 Gene3D G3DSA:3.40.1260.10 1 133 2.4E-43 T 31-10-2018 IPR027396 DsrEFH-like DFR86_10745 d85f262e6834f1032e70f4c053899bd2 133 SUPERFAMILY SSF75169 16 133 1.26E-22 T 31-10-2018 IPR027396 DsrEFH-like DFR86_07485 bd5a7e835203ea1b3e9c6cef131e855d 229 Gene3D G3DSA:4.10.1060.10 1 32 7.7E-6 T 31-10-2018 DFR86_07485 bd5a7e835203ea1b3e9c6cef131e855d 229 SMART SM00240 150 200 4.3E-14 T 31-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DFR86_07485 bd5a7e835203ea1b3e9c6cef131e855d 229 Gene3D G3DSA:2.60.200.20 120 229 2.7E-32 T 31-10-2018 DFR86_07485 bd5a7e835203ea1b3e9c6cef131e855d 229 SUPERFAMILY SSF49879 91 227 1.17E-22 T 31-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 DFR86_07485 bd5a7e835203ea1b3e9c6cef131e855d 229 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 3 22 - T 31-10-2018 IPR001876 Zinc finger, RanBP2-type DFR86_07485 bd5a7e835203ea1b3e9c6cef131e855d 229 Pfam PF00498 FHA domain 151 219 1.3E-16 T 31-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DFR86_07485 bd5a7e835203ea1b3e9c6cef131e855d 229 Pfam PF13240 zinc-ribbon domain 4 25 2.0E-7 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR86_01795 5b2320224b747baa4dc27ba04089418e 219 Gene3D G3DSA:1.20.58.220 6 215 4.6E-26 T 31-10-2018 IPR038078 PhoU-like domain superfamily DFR86_01795 5b2320224b747baa4dc27ba04089418e 219 Pfam PF01865 Protein of unknown function DUF47 12 214 2.5E-14 T 31-10-2018 IPR018445 Putative phosphate transport regulator DFR86_04675 fde883bb1420972b420b081586b09c06 277 SUPERFAMILY SSF103481 175 272 5.36E-10 T 31-10-2018 DFR86_04675 fde883bb1420972b420b081586b09c06 277 Pfam PF00892 EamA-like transporter family 140 272 1.0E-16 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR86_04675 fde883bb1420972b420b081586b09c06 277 Pfam PF00892 EamA-like transporter family 15 133 3.3E-13 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR86_02285 3c0c65485a175630e36b56d599e82d49 121 Gene3D G3DSA:2.40.50.140 48 119 1.4E-14 T 31-10-2018 DFR86_02285 3c0c65485a175630e36b56d599e82d49 121 SUPERFAMILY SSF141322 53 114 4.32E-15 T 31-10-2018 DFR86_02285 3c0c65485a175630e36b56d599e82d49 121 Pfam PF01957 NfeD-like C-terminal, partner-binding 9 115 4.5E-16 T 31-10-2018 IPR002810 NfeD-like, C-terminal domain DFR86_00680 c20af3b253120857668faf6eaa842381 587 SMART SM00116 528 575 1.4 T 31-10-2018 IPR000644 CBS domain DFR86_00680 c20af3b253120857668faf6eaa842381 587 SMART SM00116 469 517 0.0034 T 31-10-2018 IPR000644 CBS domain DFR86_00680 c20af3b253120857668faf6eaa842381 587 Gene3D G3DSA:3.10.580.10 459 585 2.4E-18 T 31-10-2018 DFR86_00680 c20af3b253120857668faf6eaa842381 587 Pfam PF00654 Voltage gated chloride channel 79 431 1.6E-90 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR86_00680 c20af3b253120857668faf6eaa842381 587 SUPERFAMILY SSF81340 6 449 6.54E-103 T 31-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 DFR86_00680 c20af3b253120857668faf6eaa842381 587 Pfam PF00571 CBS domain 470 512 4.3E-7 T 31-10-2018 IPR000644 CBS domain DFR86_00680 c20af3b253120857668faf6eaa842381 587 Pfam PF00571 CBS domain 531 573 1.7E-5 T 31-10-2018 IPR000644 CBS domain DFR86_00680 c20af3b253120857668faf6eaa842381 587 Gene3D G3DSA:1.10.3080.10 11 458 1.6E-97 T 31-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 DFR86_00680 c20af3b253120857668faf6eaa842381 587 PRINTS PR00762 Chloride channel signature 346 366 3.5E-20 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR86_00680 c20af3b253120857668faf6eaa842381 587 PRINTS PR00762 Chloride channel signature 399 418 3.5E-20 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR86_00680 c20af3b253120857668faf6eaa842381 587 PRINTS PR00762 Chloride channel signature 173 192 3.5E-20 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR86_00680 c20af3b253120857668faf6eaa842381 587 PRINTS PR00762 Chloride channel signature 122 141 3.5E-20 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR86_00680 c20af3b253120857668faf6eaa842381 587 PRINTS PR00762 Chloride channel signature 381 397 3.5E-20 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR86_00680 c20af3b253120857668faf6eaa842381 587 SUPERFAMILY SSF54631 458 580 4.8E-23 T 31-10-2018 DFR86_00355 3b0bbea753111273bb66bbbd17e0b17f 526 Gene3D G3DSA:3.40.190.10 202 468 6.6E-61 T 31-10-2018 DFR86_00355 3b0bbea753111273bb66bbbd17e0b17f 526 Pfam PF13416 Bacterial extracellular solute-binding protein 110 410 3.5E-21 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein DFR86_00355 3b0bbea753111273bb66bbbd17e0b17f 526 SUPERFAMILY SSF53850 89 478 3.31E-56 T 31-10-2018 DFR86_00355 3b0bbea753111273bb66bbbd17e0b17f 526 Gene3D G3DSA:3.40.190.10 101 443 6.6E-61 T 31-10-2018 DFR86_06095 89b0f5cc93b8867e32ace89ee795f8b2 324 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 81 268 1.3E-19 T 31-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 DFR86_06095 89b0f5cc93b8867e32ace89ee795f8b2 324 SUPERFAMILY SSF51726 8 315 2.35E-39 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 DFR86_06095 89b0f5cc93b8867e32ace89ee795f8b2 324 Gene3D G3DSA:3.20.20.210 9 322 4.0E-39 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 DFR86_00470 7a21e6cb725ea157ad72c4c1219a8da1 243 SMART SM00893 19 206 1.4E-37 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR86_00470 7a21e6cb725ea157ad72c4c1219a8da1 243 Pfam PF01012 Electron transfer flavoprotein domain 27 199 8.6E-35 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR86_00470 7a21e6cb725ea157ad72c4c1219a8da1 243 SUPERFAMILY SSF52402 1 233 4.4E-55 T 31-10-2018 DFR86_00470 7a21e6cb725ea157ad72c4c1219a8da1 243 Gene3D G3DSA:3.40.50.620 1 241 3.9E-58 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_00470 7a21e6cb725ea157ad72c4c1219a8da1 243 PIRSF PIRSF000090 1 243 4.4E-62 T 31-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 DFR86_11565 e25d70659756f6482b71442c9af68baa 241 Gene3D G3DSA:1.10.3210.30 1 208 5.1E-30 T 31-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily DFR86_11565 e25d70659756f6482b71442c9af68baa 241 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 12 216 1.3E-15 T 31-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain DFR86_07925 93c429bde107f73f6bc306ffe13cf483 321 SUPERFAMILY SSF52540 6 224 1.67E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07925 93c429bde107f73f6bc306ffe13cf483 321 Pfam PF13732 Domain of unknown function (DUF4162) 215 296 1.0E-7 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 DFR86_07925 93c429bde107f73f6bc306ffe13cf483 321 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 298 3.4E-95 T 31-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 DFR86_07925 93c429bde107f73f6bc306ffe13cf483 321 Pfam PF00005 ABC transporter 20 160 9.4E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_07925 93c429bde107f73f6bc306ffe13cf483 321 SMART SM00382 28 209 1.2E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_07925 93c429bde107f73f6bc306ffe13cf483 321 Gene3D G3DSA:3.40.50.300 2 237 3.5E-62 T 31-10-2018 DFR86_11205 0a5a3651a7749ce764533805863e210f 88 Gene3D G3DSA:3.30.70.20 14 57 5.6E-6 T 31-10-2018 DFR86_11205 0a5a3651a7749ce764533805863e210f 88 Gene3D G3DSA:3.30.70.20 58 88 1.8E-8 T 31-10-2018 DFR86_11205 0a5a3651a7749ce764533805863e210f 88 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 11 86 1.9E-34 T 31-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 DFR86_11205 0a5a3651a7749ce764533805863e210f 88 SUPERFAMILY SSF54862 11 85 2.09E-21 T 31-10-2018 DFR86_11205 0a5a3651a7749ce764533805863e210f 88 Pfam PF14697 4Fe-4S dicluster domain 30 83 9.3E-10 T 31-10-2018 DFR86_11205 0a5a3651a7749ce764533805863e210f 88 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR86_11335 cdbf0806d9cb53e7e64bf09e513d8f68 191 SUPERFAMILY SSF48613 2 191 1.09E-33 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR86_11335 cdbf0806d9cb53e7e64bf09e513d8f68 191 Gene3D G3DSA:1.20.910.10 1 191 1.6E-18 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR86_11335 cdbf0806d9cb53e7e64bf09e513d8f68 191 Pfam PF03070 TENA/THI-4/PQQC family 7 191 7.7E-17 T 31-10-2018 IPR004305 Thiaminase-2/PQQC DFR86_00925 a4ac040049ad0fd396d73df26097e790 265 Pfam PF00535 Glycosyl transferase family 2 12 90 9.5E-10 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_00925 a4ac040049ad0fd396d73df26097e790 265 SUPERFAMILY SSF53448 1 235 6.05E-17 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00925 a4ac040049ad0fd396d73df26097e790 265 Gene3D G3DSA:3.90.550.10 1 204 8.0E-13 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_10800 fde96b368e3defdd72d48b308acc60a4 139 SUPERFAMILY SSF51230 10 129 2.67E-26 T 31-10-2018 IPR011053 Single hybrid motif DFR86_10800 fde96b368e3defdd72d48b308acc60a4 139 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 133 31.63 T 31-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 DFR86_10800 fde96b368e3defdd72d48b308acc60a4 139 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 55 84 - T 31-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 DFR86_10800 fde96b368e3defdd72d48b308acc60a4 139 Pfam PF01597 Glycine cleavage H-protein 15 120 3.2E-31 T 31-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate DFR86_10800 fde96b368e3defdd72d48b308acc60a4 139 Gene3D G3DSA:2.40.50.100 8 132 5.3E-31 T 31-10-2018 DFR86_03355 1be3a214fb17de200ba54c9c123b956b 271 Gene3D G3DSA:3.60.20.30 137 270 5.3E-36 T 31-10-2018 DFR86_03355 1be3a214fb17de200ba54c9c123b956b 271 Pfam PF01112 Asparaginase 135 264 1.2E-38 T 31-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 DFR86_03355 1be3a214fb17de200ba54c9c123b956b 271 Pfam PF01112 Asparaginase 6 124 3.8E-33 T 31-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 DFR86_03355 1be3a214fb17de200ba54c9c123b956b 271 SUPERFAMILY SSF56235 5 263 1.23E-70 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR86_02370 3f7944a1f52389e66e4503bd9af523c7 267 Gene3D G3DSA:3.60.110.10 1 252 1.4E-71 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR86_02370 3f7944a1f52389e66e4503bd9af523c7 267 SUPERFAMILY SSF56317 2 256 3.27E-58 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR86_02370 3f7944a1f52389e66e4503bd9af523c7 267 Pfam PF00795 Carbon-nitrogen hydrolase 5 249 1.7E-30 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 DFR86_02165 bbf4090214b7116d58afb03a558e0859 349 Gene3D G3DSA:3.40.50.150 88 343 7.7E-60 T 31-10-2018 DFR86_02165 bbf4090214b7116d58afb03a558e0859 349 Pfam PF01189 16S rRNA methyltransferase RsmB/F 156 342 8.3E-36 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 DFR86_02165 bbf4090214b7116d58afb03a558e0859 349 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 138 152 3.0E-18 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_02165 bbf4090214b7116d58afb03a558e0859 349 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 167 177 3.0E-18 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_02165 bbf4090214b7116d58afb03a558e0859 349 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 231 243 3.0E-18 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_02165 bbf4090214b7116d58afb03a558e0859 349 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 278 294 3.0E-18 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_02165 bbf4090214b7116d58afb03a558e0859 349 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 327 344 3.0E-18 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_02165 bbf4090214b7116d58afb03a558e0859 349 SUPERFAMILY SSF53335 67 342 9.69E-48 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_06150 b942c50c2175c8bf02896f22fef97b0a 107 Pfam PF12136 RNA polymerase Rpo13 subunit HTH domain 17 56 2.7E-15 T 31-10-2018 IPR021985 RNA polymerase Rpo13 subunit HTH domain DFR86_10440 a91b5111cd68a5a8654796c7b6894a76 326 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 268 4.8E-37 T 31-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 DFR86_10440 a91b5111cd68a5a8654796c7b6894a76 326 SUPERFAMILY SSF53067 2 105 3.4E-13 T 31-10-2018 DFR86_10440 a91b5111cd68a5a8654796c7b6894a76 326 SUPERFAMILY SSF53067 110 275 1.61E-31 T 31-10-2018 DFR86_10440 a91b5111cd68a5a8654796c7b6894a76 326 Gene3D G3DSA:3.30.420.40 109 270 4.2E-53 T 31-10-2018 DFR86_10440 a91b5111cd68a5a8654796c7b6894a76 326 Gene3D G3DSA:3.30.420.40 3 279 4.2E-53 T 31-10-2018 DFR86_09500 ee34d8853f766ea05d23b74c4e5c5c90 325 Gene3D G3DSA:3.50.50.60 91 323 3.3E-19 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_09500 ee34d8853f766ea05d23b74c4e5c5c90 325 SUPERFAMILY SSF51905 3 257 2.75E-9 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_09115 57bd0c1dbe811c3dc7ff7ad96752bbe4 284 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 53 260 2.9E-62 T 31-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 DFR86_09115 57bd0c1dbe811c3dc7ff7ad96752bbe4 284 SUPERFAMILY SSF54211 52 128 1.41E-6 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR86_09115 57bd0c1dbe811c3dc7ff7ad96752bbe4 284 PIRSF PIRSF004884 1 283 1.3E-85 T 31-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 DFR86_07615 1c97e3f99b49ddaca90a49124d708d9b 223 SUPERFAMILY SSF51730 4 119 3.14E-5 T 31-10-2018 IPR029041 FAD-linked oxidoreductase-like DFR86_08735 710d12a7cf00c63847d2d340ef0a8e0e 163 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 20 159 1.7E-13 T 31-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_08735 710d12a7cf00c63847d2d340ef0a8e0e 163 Gene3D G3DSA:1.20.120.1200 7 161 2.6E-8 T 31-10-2018 DFR86_02110 5e446ed9e1fe042bff15047b9b6ba37c 243 Pfam PF07758 Protein of unknown function (DUF1614) 62 234 6.1E-46 T 31-10-2018 IPR011672 Protein of unknown function DUF1614 DFR86_01765 2c661a5fac5d12ad242518c74663f07b 199 Gene3D G3DSA:3.40.50.850 7 199 8.1E-58 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 DFR86_01765 2c661a5fac5d12ad242518c74663f07b 199 SUPERFAMILY SSF52499 8 196 4.06E-60 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 DFR86_01765 2c661a5fac5d12ad242518c74663f07b 199 Pfam PF00857 Isochorismatase family 21 180 2.3E-40 T 31-10-2018 IPR000868 Isochorismatase-like GO:0003824 DFR86_02565 d57cdfd9caee00eb0d514852a711e1cd 288 SUPERFAMILY SSF53850 4 279 8.84E-46 T 31-10-2018 DFR86_02565 d57cdfd9caee00eb0d514852a711e1cd 288 Pfam PF02621 Menaquinone biosynthesis 4 275 8.2E-58 T 31-10-2018 IPR003773 Menaquinone biosynthesis enzyme DFR86_02565 d57cdfd9caee00eb0d514852a711e1cd 288 Gene3D G3DSA:3.40.190.10 83 184 1.8E-25 T 31-10-2018 DFR86_02565 d57cdfd9caee00eb0d514852a711e1cd 288 Gene3D G3DSA:3.40.190.10 14 243 1.8E-25 T 31-10-2018 DFR86_05585 fe8b2477cb6891fccbec5caad8ee9b2a 399 Gene3D G3DSA:3.30.450.380 14 136 1.1E-6 T 31-10-2018 DFR86_06665 faf237114ea5e0608180c4643821df03 215 SUPERFAMILY SSF54189 3 193 2.54E-73 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06665 faf237114ea5e0608180c4643821df03 215 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 3 195 38.637 T 31-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06665 faf237114ea5e0608180c4643821df03 215 SMART SM01384 4 191 7.2E-100 T 31-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06665 faf237114ea5e0608180c4643821df03 215 Gene3D G3DSA:3.40.1120.10 2 197 3.4E-71 T 31-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06665 faf237114ea5e0608180c4643821df03 215 Pfam PF00827 Ribosomal L15 4 181 2.7E-72 T 31-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_05130 4beb337d39b481023445ffd0f4ea753d 155 Pfam PF07301 Protein of unknown function (DUF1453) 13 138 1.9E-7 T 31-10-2018 IPR009916 Protein of unknown function DUF1453 DFR86_07725 3fb181034b479ca45d00747157358e10 144 Pfam PF13936 Helix-turn-helix domain 94 134 1.1E-7 T 31-10-2018 IPR025246 Transposase IS30-like HTH domain DFR86_07725 3fb181034b479ca45d00747157358e10 144 Gene3D G3DSA:1.10.10.60 48 95 7.2E-7 T 31-10-2018 DFR86_07725 3fb181034b479ca45d00747157358e10 144 Gene3D G3DSA:1.10.10.60 96 139 1.4E-14 T 31-10-2018 DFR86_07725 3fb181034b479ca45d00747157358e10 144 Gene3D G3DSA:1.10.10.60 3 45 1.6E-6 T 31-10-2018 DFR86_07725 3fb181034b479ca45d00747157358e10 144 SUPERFAMILY SSF46689 92 137 3.88E-5 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 DFR86_07725 3fb181034b479ca45d00747157358e10 144 SUPERFAMILY SSF46689 49 88 1.37E-5 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 DFR86_10240 e21d61e9a080560d73782a4d71577ba3 283 SUPERFAMILY SSF63829 6 276 4.74E-63 T 31-10-2018 DFR86_10240 e21d61e9a080560d73782a4d71577ba3 283 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 13 253 7.3E-79 T 31-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region DFR86_10240 e21d61e9a080560d73782a4d71577ba3 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 12 29 2.3E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_10240 e21d61e9a080560d73782a4d71577ba3 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 151 171 2.3E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_10240 e21d61e9a080560d73782a4d71577ba3 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 128 150 2.3E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_10240 e21d61e9a080560d73782a4d71577ba3 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 87 108 2.3E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_10240 e21d61e9a080560d73782a4d71577ba3 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 191 208 2.3E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_10240 e21d61e9a080560d73782a4d71577ba3 283 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 234 252 2.3E-45 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR86_10240 e21d61e9a080560d73782a4d71577ba3 283 Gene3D G3DSA:2.120.10.30 1 281 2.5E-90 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like DFR86_03040 a6c56c3fecb36c240c584572c8d67ca3 518 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 61 4.5E-11 T 31-10-2018 DFR86_03040 a6c56c3fecb36c240c584572c8d67ca3 518 Gene3D G3DSA:3.50.50.60 166 326 1.3E-21 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03040 a6c56c3fecb36c240c584572c8d67ca3 518 Gene3D G3DSA:3.50.50.60 2 110 2.0E-13 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_03040 a6c56c3fecb36c240c584572c8d67ca3 518 SUPERFAMILY SSF51905 2 501 2.85E-47 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_04750 1c0c7a7ff851cce467705ae9d35e4d9a 197 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 82 152 6.8E-7 T 31-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04750 1c0c7a7ff851cce467705ae9d35e4d9a 197 SUPERFAMILY SSF49503 56 169 4.35E-22 T 31-10-2018 IPR008972 Cupredoxin DFR86_04750 1c0c7a7ff851cce467705ae9d35e4d9a 197 Gene3D G3DSA:2.60.40.2600 58 185 3.2E-23 T 31-10-2018 DFR86_10855 97f368d62bc89b8cac0b9fb6455be428 230 Hamap MF_00401 Peroxiredoxin. 9 216 50.956 T 31-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DFR86_10855 97f368d62bc89b8cac0b9fb6455be428 230 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 161 201 5.4E-8 T 31-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_10855 97f368d62bc89b8cac0b9fb6455be428 230 Pfam PF00578 AhpC/TSA family 11 140 2.5E-31 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_10855 97f368d62bc89b8cac0b9fb6455be428 230 PIRSF PIRSF000239 4 223 5.8E-78 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR86_10855 97f368d62bc89b8cac0b9fb6455be428 230 Gene3D G3DSA:3.30.1020.20 150 230 3.6E-26 T 31-10-2018 DFR86_10855 97f368d62bc89b8cac0b9fb6455be428 230 SUPERFAMILY SSF52833 9 219 7.29E-66 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_10855 97f368d62bc89b8cac0b9fb6455be428 230 Gene3D G3DSA:3.40.30.10 10 149 2.6E-45 T 31-10-2018 DFR86_02300 0616d22001616b6a9e875a8b023e4dc8 97 SUPERFAMILY SSF55248 1 91 9.55E-31 T 31-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 DFR86_02300 0616d22001616b6a9e875a8b023e4dc8 97 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 92 22.974 T 31-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 DFR86_02300 0616d22001616b6a9e875a8b023e4dc8 97 Gene3D G3DSA:3.30.1360.20 2 97 2.8E-31 T 31-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 DFR86_02300 0616d22001616b6a9e875a8b023e4dc8 97 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 3 91 2.7E-29 T 31-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 DFR86_10920 2d5384faa42a68ec59bf55ec2aefb643 309 Gene3D G3DSA:3.30.479.30 96 208 5.5E-5 T 31-10-2018 DFR86_10920 2d5384faa42a68ec59bf55ec2aefb643 309 Pfam PF01145 SPFH domain / Band 7 family 42 215 2.5E-21 T 31-10-2018 IPR001107 Band 7 domain DFR86_10920 2d5384faa42a68ec59bf55ec2aefb643 309 SUPERFAMILY SSF117892 88 212 1.83E-9 T 31-10-2018 IPR036013 Band 7/SPFH domain superfamily DFR86_10955 9a485ee30732f0c1001944434ca576bd 370 SUPERFAMILY SSF53187 7 330 1.19E-17 T 31-10-2018 DFR86_10955 9a485ee30732f0c1001944434ca576bd 370 Gene3D G3DSA:3.40.630.10 132 333 2.1E-17 T 31-10-2018 DFR86_10955 9a485ee30732f0c1001944434ca576bd 370 Pfam PF04389 Peptidase family M28 168 322 3.6E-9 T 31-10-2018 IPR007484 Peptidase M28 DFR86_05570 195f43bde1e62dc58a15f52755ba02f3 289 SUPERFAMILY SSF51905 2 221 7.33E-14 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05570 195f43bde1e62dc58a15f52755ba02f3 289 Gene3D G3DSA:3.50.50.100 159 281 1.7E-5 T 31-10-2018 DFR86_05570 195f43bde1e62dc58a15f52755ba02f3 289 Gene3D G3DSA:3.50.50.100 1 95 5.0E-10 T 31-10-2018 DFR86_04000 2f2e1ac7e08fedda089fd5afd4fbbebd 109 Gene3D G3DSA:2.40.50.970 1 78 4.0E-17 T 31-10-2018 IPR037254 HupF/HypC superfamily DFR86_04000 2f2e1ac7e08fedda089fd5afd4fbbebd 109 Pfam PF01455 HupF/HypC family 1 65 6.6E-16 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DFR86_04000 2f2e1ac7e08fedda089fd5afd4fbbebd 109 SUPERFAMILY SSF159127 1 75 9.16E-16 T 31-10-2018 IPR037254 HupF/HypC superfamily DFR86_04210 9470c36c23046f9f2f4272d1f44d3d50 447 SUPERFAMILY SSF53383 16 431 3.98E-94 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_04210 9470c36c23046f9f2f4272d1f44d3d50 447 Gene3D G3DSA:3.40.640.10 81 326 9.0E-142 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_04210 9470c36c23046f9f2f4272d1f44d3d50 447 Pfam PF00202 Aminotransferase class-III 43 352 1.1E-63 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR86_04210 9470c36c23046f9f2f4272d1f44d3d50 447 Gene3D G3DSA:3.90.1150.10 23 425 9.0E-142 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_00775 6b8a139a7075b365ed0440c317623999 271 SUPERFAMILY SSF53448 8 162 1.59E-14 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00775 6b8a139a7075b365ed0440c317623999 271 Gene3D G3DSA:3.90.550.10 3 188 1.7E-14 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00775 6b8a139a7075b365ed0440c317623999 271 Pfam PF00535 Glycosyl transferase family 2 9 52 2.8E-6 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_05645 2b36fb5dac2facd509bdf5906b31783e 284 Gene3D G3DSA:3.90.180.10 7 154 4.5E-12 T 31-10-2018 DFR86_05645 2b36fb5dac2facd509bdf5906b31783e 284 SUPERFAMILY SSF50129 8 147 3.28E-12 T 31-10-2018 IPR011032 GroES-like superfamily DFR86_06505 6f2b8acda5749b84433cbeb802458ce4 173 SUPERFAMILY SSF57783 1 34 1.7E-7 T 31-10-2018 DFR86_06505 6f2b8acda5749b84433cbeb802458ce4 173 Pfam PF08271 TFIIB zinc-binding 1 30 4.1E-8 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type DFR86_06505 6f2b8acda5749b84433cbeb802458ce4 173 Gene3D G3DSA:2.20.25.10 1 37 7.4E-8 T 31-10-2018 DFR86_03310 42457ac03c1486a982cf2b79c93a8c3a 290 Pfam PF02754 Cysteine-rich domain 148 238 3.0E-13 T 31-10-2018 IPR004017 Cysteine-rich domain DFR86_03310 42457ac03c1486a982cf2b79c93a8c3a 290 Pfam PF02754 Cysteine-rich domain 3 83 2.7E-19 T 31-10-2018 IPR004017 Cysteine-rich domain DFR86_05385 299513cdceba522d0c435bb9e4c04867 190 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 3 181 8.3E-40 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 DFR86_05385 299513cdceba522d0c435bb9e4c04867 190 Gene3D G3DSA:3.40.50.300 1 189 4.8E-48 T 31-10-2018 DFR86_05385 299513cdceba522d0c435bb9e4c04867 190 Pfam PF02223 Thymidylate kinase 6 180 7.1E-39 T 31-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DFR86_05385 299513cdceba522d0c435bb9e4c04867 190 ProSitePatterns PS01331 Thymidylate kinase signature. 84 96 - T 31-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 DFR86_05385 299513cdceba522d0c435bb9e4c04867 190 Hamap MF_00165 Thymidylate kinase [tmk]. 2 189 21.354 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 DFR86_05385 299513cdceba522d0c435bb9e4c04867 190 SUPERFAMILY SSF52540 1 189 6.97E-37 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_09860 a092b4d5dfc4d43766590cc3ab8974eb 482 SUPERFAMILY SSF103365 5 482 1.44E-166 T 31-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 DFR86_09860 a092b4d5dfc4d43766590cc3ab8974eb 482 Pfam PF01139 tRNA-splicing ligase RtcB 47 482 3.6E-160 T 31-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 DFR86_09860 a092b4d5dfc4d43766590cc3ab8974eb 482 Gene3D G3DSA:3.90.1860.10 1 482 7.1E-192 T 31-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 DFR86_09675 01e3fafba7c9e601ebf7c3f80713e20d 227 SUPERFAMILY SSF56529 3 217 7.17E-27 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR86_09675 01e3fafba7c9e601ebf7c3f80713e20d 227 Gene3D G3DSA:3.90.850.10 2 223 1.2E-26 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR86_09060 67f56f4181df5ffc74310bab3b781b29 375 Pfam PF13531 Bacterial extracellular solute-binding protein 58 328 1.5E-26 T 31-10-2018 DFR86_09060 67f56f4181df5ffc74310bab3b781b29 375 Gene3D G3DSA:3.40.190.10 58 344 4.4E-31 T 31-10-2018 DFR86_09060 67f56f4181df5ffc74310bab3b781b29 375 Gene3D G3DSA:3.40.190.10 138 307 4.4E-31 T 31-10-2018 DFR86_09060 67f56f4181df5ffc74310bab3b781b29 375 SUPERFAMILY SSF53850 56 345 1.88E-26 T 31-10-2018 DFR86_01265 c2beff675414c8ed709e542aa68d8000 395 SUPERFAMILY SSF54862 25 113 4.31E-7 T 31-10-2018 DFR86_01265 c2beff675414c8ed709e542aa68d8000 395 Pfam PF02754 Cysteine-rich domain 165 248 8.4E-11 T 31-10-2018 IPR004017 Cysteine-rich domain DFR86_01265 c2beff675414c8ed709e542aa68d8000 395 Pfam PF02754 Cysteine-rich domain 291 368 0.0025 T 31-10-2018 IPR004017 Cysteine-rich domain DFR86_01265 c2beff675414c8ed709e542aa68d8000 395 Gene3D G3DSA:3.30.70.20 13 89 1.1E-5 T 31-10-2018 DFR86_00790 035b2545c2552b4d990845cbc356b15f 304 Pfam PF00535 Glycosyl transferase family 2 8 93 3.6E-8 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_00790 035b2545c2552b4d990845cbc356b15f 304 Gene3D G3DSA:3.90.550.10 5 201 1.0E-10 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00790 035b2545c2552b4d990845cbc356b15f 304 SUPERFAMILY SSF53448 8 147 7.65E-12 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_04895 b4369a038497f5f9b4e2d22c8b029e5a 598 SUPERFAMILY SSF48208 175 580 4.86E-86 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR86_04895 b4369a038497f5f9b4e2d22c8b029e5a 598 Gene3D G3DSA:1.50.10.10 216 589 2.9E-77 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR86_04895 b4369a038497f5f9b4e2d22c8b029e5a 598 Pfam PF00723 Glycosyl hydrolases family 15 216 524 1.1E-52 T 31-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 DFR86_02595 a22c25053c60dbc27c741923b1b3e18b 97 Gene3D G3DSA:2.20.25.200 54 97 5.7E-14 T 31-10-2018 DFR86_02595 a22c25053c60dbc27c741923b1b3e18b 97 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 1 96 21.402 T 31-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 DFR86_02595 a22c25053c60dbc27c741923b1b3e18b 97 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 13 87 7.0E-11 T 31-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 DFR86_02595 a22c25053c60dbc27c741923b1b3e18b 97 PIRSF PIRSF004878 1 97 1.8E-24 T 31-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 DFR86_08100 c32b5fd5dba343faf7995285b713d59f 247 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 247 17.199 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 DFR86_08100 c32b5fd5dba343faf7995285b713d59f 247 Pfam PF02654 Cobalamin-5-phosphate synthase 11 231 1.7E-31 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 DFR86_06185 85de10c80a1af740a61b2d7be8985aa1 85 SUPERFAMILY SSF55120 10 85 6.04E-18 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 DFR86_06185 85de10c80a1af740a61b2d7be8985aa1 85 SMART SM01136 16 64 1.3E-19 T 31-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 DFR86_06185 85de10c80a1af740a61b2d7be8985aa1 85 Pfam PF08068 DKCLD (NUC011) domain 17 63 2.2E-15 T 31-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 DFR86_06185 85de10c80a1af740a61b2d7be8985aa1 85 Gene3D G3DSA:3.30.2350.10 41 84 7.6E-23 T 31-10-2018 DFR86_06185 85de10c80a1af740a61b2d7be8985aa1 85 Gene3D G3DSA:2.30.130.70 25 40 7.6E-23 T 31-10-2018 DFR86_06310 5dfe1e3057249fdce5ca96654ccd3eb6 581 Pfam PF13394 4Fe-4S single cluster domain 142 227 1.3E-6 T 31-10-2018 DFR86_06310 5dfe1e3057249fdce5ca96654ccd3eb6 581 Gene3D G3DSA:3.20.20.70 130 403 1.4E-29 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_06310 5dfe1e3057249fdce5ca96654ccd3eb6 581 Pfam PF04055 Radical SAM superfamily 141 305 8.5E-18 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_06310 5dfe1e3057249fdce5ca96654ccd3eb6 581 SUPERFAMILY SSF102114 125 404 7.32E-38 T 31-10-2018 DFR86_02125 022db4fa9244cb7c04c7a0a9dcc6ff44 240 Gene3D G3DSA:3.40.50.300 2 238 3.2E-69 T 31-10-2018 DFR86_02125 022db4fa9244cb7c04c7a0a9dcc6ff44 240 Pfam PF00005 ABC transporter 19 158 5.1E-33 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_02125 022db4fa9244cb7c04c7a0a9dcc6ff44 240 SUPERFAMILY SSF52540 3 221 1.61E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_02125 022db4fa9244cb7c04c7a0a9dcc6ff44 240 SMART SM00382 28 215 7.9E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_10980 c4a46d520ea9e35099bdc98abd624d20 275 SMART SM00729 21 225 8.5E-23 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_10980 c4a46d520ea9e35099bdc98abd624d20 275 SUPERFAMILY SSF102114 27 255 5.23E-32 T 31-10-2018 DFR86_10980 c4a46d520ea9e35099bdc98abd624d20 275 Gene3D G3DSA:3.20.20.70 10 238 1.3E-22 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_08765 d7f0e10110a10025235684828f0c49bd 256 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 2 208 30.704 T 31-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 DFR86_08765 d7f0e10110a10025235684828f0c49bd 256 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 4 199 4.6E-63 T 31-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 DFR86_08765 d7f0e10110a10025235684828f0c49bd 256 Gene3D G3DSA:3.30.1360.170 1 206 1.7E-64 T 31-10-2018 DFR86_08765 d7f0e10110a10025235684828f0c49bd 256 SUPERFAMILY SSF69796 3 206 7.19E-63 T 31-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 DFR86_08765 d7f0e10110a10025235684828f0c49bd 256 Pfam PF02511 Thymidylate synthase complementing protein 6 194 1.9E-65 T 31-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 DFR86_00780 ea8351a2a5d11c5dbe34396615dc6cf7 62 Gene3D G3DSA:3.90.550.10 1 61 4.3E-5 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00780 ea8351a2a5d11c5dbe34396615dc6cf7 62 SUPERFAMILY SSF53448 2 50 3.83E-6 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_04375 be29a44df4815729b703bb451b1a0b73 393 Gene3D G3DSA:3.30.390.10 6 366 1.4E-111 T 31-10-2018 IPR029017 Enolase-like, N-terminal DFR86_04375 be29a44df4815729b703bb451b1a0b73 393 SUPERFAMILY SSF51604 106 369 4.98E-75 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR86_04375 be29a44df4815729b703bb451b1a0b73 393 Gene3D G3DSA:3.20.20.120 112 357 1.4E-111 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR86_04375 be29a44df4815729b703bb451b1a0b73 393 SUPERFAMILY SSF54826 1 123 8.61E-26 T 31-10-2018 DFR86_04375 be29a44df4815729b703bb451b1a0b73 393 SMART SM00922 139 244 1.6E-19 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DFR86_04375 be29a44df4815729b703bb451b1a0b73 393 Pfam PF13378 Enolase C-terminal domain-like 142 364 2.1E-56 T 31-10-2018 IPR029065 Enolase C-terminal domain-like DFR86_04375 be29a44df4815729b703bb451b1a0b73 393 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 21 118 2.4E-14 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DFR86_05575 bd77f5dee11632868c3a2443e07b5275 364 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 247 259 4.9E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_05575 bd77f5dee11632868c3a2443e07b5275 364 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 296 312 4.9E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_05575 bd77f5dee11632868c3a2443e07b5275 364 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 181 191 4.9E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_05575 bd77f5dee11632868c3a2443e07b5275 364 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 345 362 4.9E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_05575 bd77f5dee11632868c3a2443e07b5275 364 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 152 166 4.9E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR86_05575 bd77f5dee11632868c3a2443e07b5275 364 SUPERFAMILY SSF53335 80 360 9.46E-38 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_05575 bd77f5dee11632868c3a2443e07b5275 364 Gene3D G3DSA:3.40.50.150 73 361 9.2E-52 T 31-10-2018 DFR86_05575 bd77f5dee11632868c3a2443e07b5275 364 Pfam PF01189 16S rRNA methyltransferase RsmB/F 171 360 1.2E-32 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 DFR86_06480 a39d9729ebf5d6d14488e07ae243cef1 76 Gene3D G3DSA:1.10.60.20 1 62 9.0E-24 T 31-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06480 a39d9729ebf5d6d14488e07ae243cef1 76 SUPERFAMILY SSF116820 1 60 1.02E-20 T 31-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06480 a39d9729ebf5d6d14488e07ae243cef1 76 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 31-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06480 a39d9729ebf5d6d14488e07ae243cef1 76 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 18.69 T 31-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06480 a39d9729ebf5d6d14488e07ae243cef1 76 Pfam PF00833 Ribosomal S17 1 62 5.9E-14 T 31-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_07045 70db079544488f6c5c18f68ac4b5e490 571 Gene3D G3DSA:2.30.310.10 1 149 1.0E-13 T 31-10-2018 DFR86_07045 70db079544488f6c5c18f68ac4b5e490 571 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 3 151 1.1E-17 T 31-10-2018 DFR86_07045 70db079544488f6c5c18f68ac4b5e490 571 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 172 365 1.2E-12 T 31-10-2018 DFR86_07045 70db079544488f6c5c18f68ac4b5e490 571 Pfam PF05670 Domain of unknown function (DUF814) 374 473 1.4E-25 T 31-10-2018 IPR008532 Domain of unknown function DUF814 DFR86_07160 a7ced9f14f746a50371a3590362badca 65 Pfam PF07754 Domain of unknown function (DUF1610) 16 39 6.4E-13 T 31-10-2018 IPR011668 Domain of unknown function DUF1610 DFR86_06675 af09a76a0e3483bdf7bb64cd4eac2b41 187 SUPERFAMILY SSF89550 59 179 2.79E-8 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 DFR86_10370 5485be36ee1007823edcd79a915f868b 308 Pfam PF07682 Sulphur oxygenase reductase 4 303 2.9E-140 T 31-10-2018 IPR011661 Sulphur oxygenase reductase KEGG: 00920+1.13.11.55|MetaCyc: PWY-5302 DFR86_10370 5485be36ee1007823edcd79a915f868b 308 SUPERFAMILY SSF54909 2 308 8.28E-134 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR86_08595 1fe42f44a2b4ed6e9fd7e2a11290a340 124 SUPERFAMILY SSF55021 15 78 3.51E-5 T 31-10-2018 DFR86_08595 1fe42f44a2b4ed6e9fd7e2a11290a340 124 Pfam PF13710 ACT domain 15 75 1.4E-10 T 31-10-2018 DFR86_00190 b758e32109850fa3298b2667f978c893 1161 Pfam PF05317 Thermopsin 76 326 2.4E-79 T 31-10-2018 IPR007981 Peptidase A5, thermopsin DFR86_09170 6214bce58c11edd96eacfe518d125b19 292 SUPERFAMILY SSF53686 14 291 7.46E-61 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR86_09170 6214bce58c11edd96eacfe518d125b19 292 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 277 4.4E-47 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR86_09170 6214bce58c11edd96eacfe518d125b19 292 Gene3D G3DSA:3.40.50.1100 49 144 8.5E-64 T 31-10-2018 DFR86_09170 6214bce58c11edd96eacfe518d125b19 292 Gene3D G3DSA:3.40.50.1100 21 285 8.5E-64 T 31-10-2018 DFR86_09170 6214bce58c11edd96eacfe518d125b19 292 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 35 54 - T 31-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 DFR86_11005 2ece46ffddcead380c34f4b1221f22f6 149 SUPERFAMILY SSF55729 3 131 1.86E-27 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR86_11005 2ece46ffddcead380c34f4b1221f22f6 149 Pfam PF13673 Acetyltransferase (GNAT) domain 33 131 2.3E-11 T 31-10-2018 IPR000182 GNAT domain DFR86_11005 2ece46ffddcead380c34f4b1221f22f6 149 Gene3D G3DSA:3.40.630.30 2 148 1.9E-38 T 31-10-2018 DFR86_05380 0732be6b8582e0dfae39cc435060c189 346 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 86 239 2.7E-15 T 31-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain DFR86_05380 0732be6b8582e0dfae39cc435060c189 346 Gene3D G3DSA:3.40.50.300 69 244 7.7E-9 T 31-10-2018 DFR86_04040 84b312d74770a3333c6fb3038e02ce99 125 Pfam PF00571 CBS domain 19 57 1.4E-6 T 31-10-2018 IPR000644 CBS domain DFR86_04040 84b312d74770a3333c6fb3038e02ce99 125 Pfam PF00571 CBS domain 65 118 9.6E-5 T 31-10-2018 IPR000644 CBS domain DFR86_04040 84b312d74770a3333c6fb3038e02ce99 125 Gene3D G3DSA:3.10.580.10 58 121 5.4E-8 T 31-10-2018 DFR86_04040 84b312d74770a3333c6fb3038e02ce99 125 Gene3D G3DSA:3.10.580.10 3 57 1.2E-7 T 31-10-2018 DFR86_04040 84b312d74770a3333c6fb3038e02ce99 125 SUPERFAMILY SSF54631 11 121 3.41E-21 T 31-10-2018 DFR86_04040 84b312d74770a3333c6fb3038e02ce99 125 SMART SM00116 11 59 1.8 T 31-10-2018 IPR000644 CBS domain DFR86_04040 84b312d74770a3333c6fb3038e02ce99 125 SMART SM00116 71 119 8.0 T 31-10-2018 IPR000644 CBS domain DFR86_07670 f3dbea6b0fd032659b411c84e42a2b03 244 SMART SM00933 26 210 1.3E-9 T 31-10-2018 IPR018977 NurA domain DFR86_04525 f3ea552b4032cf48db618596945af42c 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 322 8.9E-33 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_04525 f3ea552b4032cf48db618596945af42c 328 Pfam PF00005 ABC transporter 31 187 3.3E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR86_04525 f3ea552b4032cf48db618596945af42c 328 Gene3D G3DSA:3.40.50.300 8 328 2.1E-100 T 31-10-2018 DFR86_04525 f3ea552b4032cf48db618596945af42c 328 SMART SM00382 39 245 8.6E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_04525 f3ea552b4032cf48db618596945af42c 328 SUPERFAMILY SSF52540 38 320 8.87E-66 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04525 f3ea552b4032cf48db618596945af42c 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 4.7E-22 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR86_04525 f3ea552b4032cf48db618596945af42c 328 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR86_01435 3c8049356f33fe25a85a1754641052a6 411 Pfam PF00534 Glycosyl transferases group 1 222 373 9.2E-22 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR86_01435 3c8049356f33fe25a85a1754641052a6 411 SUPERFAMILY SSF53756 12 373 6.8E-32 T 31-10-2018 DFR86_01435 3c8049356f33fe25a85a1754641052a6 411 Gene3D G3DSA:3.40.50.2000 211 382 8.3E-27 T 31-10-2018 DFR86_03505 0c84788c72f038b91c1c92fa5a9114eb 240 Pfam PF01061 ABC-2 type transporter 12 200 1.1E-6 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 DFR86_09165 05407c65e255403f6027388307a1f232 220 SUPERFAMILY SSF56112 17 186 7.34E-15 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR86_09165 05407c65e255403f6027388307a1f232 220 Gene3D G3DSA:1.10.510.10 91 201 1.0E-8 T 31-10-2018 DFR86_08275 e594d432de96e61cfc109ff64c1d44ea 207 Gene3D G3DSA:1.20.58.2140 15 207 4.2E-52 T 31-10-2018 DFR86_08275 e594d432de96e61cfc109ff64c1d44ea 207 SUPERFAMILY SSF74784 16 197 9.42E-20 T 31-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 DFR86_00745 760d9d5fe39ddc72017c6d15d65caf3e 280 Pfam PF06053 Domain of unknown function (DUF929) 15 279 1.6E-69 T 31-10-2018 IPR009272 Protein of unknown function DUF929 DFR86_11075 27c4761fed7df7250b9de8ccc9a567fd 412 Pfam PF04143 Sulphur transport 34 404 1.4E-63 T 31-10-2018 IPR007272 Sulphur transport domain DFR86_01235 3382afc74ded3ef7247290b1a8d711ea 187 SUPERFAMILY SSF52540 5 56 7.08E-7 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_01235 3382afc74ded3ef7247290b1a8d711ea 187 Gene3D G3DSA:3.40.50.300 2 152 5.4E-6 T 31-10-2018 DFR86_01235 3382afc74ded3ef7247290b1a8d711ea 187 Pfam PF13614 AAA domain 5 80 1.9E-6 T 31-10-2018 IPR025669 AAA domain DFR86_05395 e9bb8ec7f537b00441e0a383aa3a9678 89 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 11 88 8.0E-34 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 DFR86_05395 e9bb8ec7f537b00441e0a383aa3a9678 89 SUPERFAMILY SSF158436 4 89 6.02E-34 T 31-10-2018 DFR86_05395 e9bb8ec7f537b00441e0a383aa3a9678 89 Pfam PF03685 Uncharacterised protein family (UPF0147) 7 87 5.4E-36 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 DFR86_05395 e9bb8ec7f537b00441e0a383aa3a9678 89 Gene3D G3DSA:1.20.1440.50 6 89 2.5E-32 T 31-10-2018 IPR023130 Ta0600-like superfamily DFR86_05395 e9bb8ec7f537b00441e0a383aa3a9678 89 Hamap MF_00342 UPF0147 protein . 7 88 30.785 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 DFR86_03255 9f98f96452e8112b83f32b61f64fdb04 330 PIRSF PIRSF029122 1 324 1.7E-120 T 31-10-2018 IPR010581 Protein of unknown function DUF1152 DFR86_03255 9f98f96452e8112b83f32b61f64fdb04 330 Pfam PF06626 Protein of unknown function (DUF1152) 4 296 8.8E-112 T 31-10-2018 IPR010581 Protein of unknown function DUF1152 DFR86_10215 f977b914f301ba4935d4105e0f4817fd 92 Gene3D G3DSA:3.40.50.1010 1 92 2.9E-34 T 31-10-2018 DFR86_04345 43e0cf44c1c6ba0e57b989261db66a2c 208 PIRSF PIRSF005624 1 206 2.4E-49 T 31-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 DFR86_04345 43e0cf44c1c6ba0e57b989261db66a2c 208 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 4 179 1.7E-30 T 31-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain DFR86_04345 43e0cf44c1c6ba0e57b989261db66a2c 208 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 2 200 5.0E-67 T 31-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 DFR86_04345 43e0cf44c1c6ba0e57b989261db66a2c 208 PRINTS PR00449 Transforming protein P21 ras signature 141 154 9.1E-6 T 31-10-2018 DFR86_04345 43e0cf44c1c6ba0e57b989261db66a2c 208 PRINTS PR00449 Transforming protein P21 ras signature 2 23 9.1E-6 T 31-10-2018 DFR86_04345 43e0cf44c1c6ba0e57b989261db66a2c 208 PRINTS PR00449 Transforming protein P21 ras signature 178 200 9.1E-6 T 31-10-2018 DFR86_04345 43e0cf44c1c6ba0e57b989261db66a2c 208 SUPERFAMILY SSF52540 3 200 1.28E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04345 43e0cf44c1c6ba0e57b989261db66a2c 208 Gene3D G3DSA:3.40.50.300 1 204 7.5E-49 T 31-10-2018 DFR86_06015 c2bab359c9bc0521779781a6ca8c8252 241 SUPERFAMILY SSF46785 10 99 1.01E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_06015 c2bab359c9bc0521779781a6ca8c8252 241 Gene3D G3DSA:1.10.10.10 11 107 4.2E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_06015 c2bab359c9bc0521779781a6ca8c8252 241 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 19 83 8.5E-20 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR86_04325 f593896d37fd8c81f129657e7e5c96a4 519 Pfam PF00324 Amino acid permease 61 468 2.1E-5 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR86_04325 f593896d37fd8c81f129657e7e5c96a4 519 PIRSF PIRSF006060 4 517 5.6E-28 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04325 f593896d37fd8c81f129657e7e5c96a4 519 Gene3D G3DSA:1.20.1740.10 23 514 7.5E-13 T 31-10-2018 DFR86_00195 e6f2aeca6d06b580a4ddf1de0678e13e 358 SMART SM00933 68 322 6.7E-18 T 31-10-2018 IPR018977 NurA domain DFR86_00195 e6f2aeca6d06b580a4ddf1de0678e13e 358 Pfam PF09376 NurA domain 74 320 4.4E-8 T 31-10-2018 IPR018977 NurA domain DFR86_01890 ef3e300069000182b052c00700e50852 44 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 38 2.0E-6 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR86_03765 1b7d6a92b3e5a6846b2cfadb2c3d378d 139 PRINTS PR01438 Universal stress protein signature 99 111 3.2E-19 T 31-10-2018 IPR006015 Universal stress protein A DFR86_03765 1b7d6a92b3e5a6846b2cfadb2c3d378d 139 PRINTS PR01438 Universal stress protein signature 2 20 3.2E-19 T 31-10-2018 IPR006015 Universal stress protein A DFR86_03765 1b7d6a92b3e5a6846b2cfadb2c3d378d 139 PRINTS PR01438 Universal stress protein signature 117 139 3.2E-19 T 31-10-2018 IPR006015 Universal stress protein A DFR86_03765 1b7d6a92b3e5a6846b2cfadb2c3d378d 139 Pfam PF00582 Universal stress protein family 2 139 7.2E-33 T 31-10-2018 IPR006016 UspA DFR86_03765 1b7d6a92b3e5a6846b2cfadb2c3d378d 139 Gene3D G3DSA:3.40.50.620 1 139 3.5E-36 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR86_03765 1b7d6a92b3e5a6846b2cfadb2c3d378d 139 SUPERFAMILY SSF52402 2 139 1.34E-33 T 31-10-2018 DFR86_10345 e0e9390102c4dcfb49b51ff660513755 591 Gene3D G3DSA:1.20.1530.20 2 369 2.5E-35 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily DFR86_10345 e0e9390102c4dcfb49b51ff660513755 591 Pfam PF00999 Sodium/hydrogen exchanger family 8 363 5.0E-25 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DFR86_04140 aa0aa41eeda0b4a8ae24f53ab6f1da34 533 Gene3D G3DSA:1.20.1740.10 17 522 3.2E-13 T 31-10-2018 DFR86_04140 aa0aa41eeda0b4a8ae24f53ab6f1da34 533 PIRSF PIRSF006060 1 526 3.3E-27 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04140 aa0aa41eeda0b4a8ae24f53ab6f1da34 533 Pfam PF13520 Amino acid permease 35 498 3.9E-17 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_11290 9591295d1d4fe2479fc6bf693d86f50d 503 Pfam PF13520 Amino acid permease 13 460 2.2E-32 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_11290 9591295d1d4fe2479fc6bf693d86f50d 503 PIRSF PIRSF006060 403 500 120.0 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_11290 9591295d1d4fe2479fc6bf693d86f50d 503 PIRSF PIRSF006060 1 448 3.2E-55 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_11290 9591295d1d4fe2479fc6bf693d86f50d 503 Gene3D G3DSA:1.20.1740.10 7 461 2.7E-51 T 31-10-2018 DFR86_10200 a51e56207a760f12e00f742a50230069 111 Gene3D G3DSA:1.10.10.10 2 110 4.1E-39 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_10200 a51e56207a760f12e00f742a50230069 111 SUPERFAMILY SSF46785 11 101 2.43E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_10200 a51e56207a760f12e00f742a50230069 111 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 17 88 2.3E-9 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR86_08000 0a37f4234fa02216a805ac0fc21a8c6c 231 Pfam PF06053 Domain of unknown function (DUF929) 6 231 1.4E-64 T 31-10-2018 IPR009272 Protein of unknown function DUF929 DFR86_04205 c2e1373d8f5632cf626742b7cba7062e 397 Pfam PF01565 FAD binding domain 42 171 4.3E-20 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR86_04205 c2e1373d8f5632cf626742b7cba7062e 397 Gene3D G3DSA:3.30.465.10 93 198 3.8E-9 T 31-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 DFR86_04205 c2e1373d8f5632cf626742b7cba7062e 397 SUPERFAMILY SSF56176 6 197 1.12E-31 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR86_04205 c2e1373d8f5632cf626742b7cba7062e 397 Gene3D G3DSA:3.30.43.10 3 92 5.6E-13 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR86_03705 ae0360b06d78b4afb35835b8bc3f4662 248 Gene3D G3DSA:3.30.1600.10 31 166 1.3E-84 T 31-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily DFR86_03705 ae0360b06d78b4afb35835b8bc3f4662 248 Gene3D G3DSA:3.40.50.1220 16 236 1.3E-84 T 31-10-2018 DFR86_03705 ae0360b06d78b4afb35835b8bc3f4662 248 Pfam PF02146 Sir2 family 22 194 4.8E-52 T 31-10-2018 IPR003000 Sirtuin family GO:0070403 DFR86_03705 ae0360b06d78b4afb35835b8bc3f4662 248 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 6 239 62.796 T 31-10-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 DFR86_03705 ae0360b06d78b4afb35835b8bc3f4662 248 SUPERFAMILY SSF52467 2 242 5.09E-83 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR86_00595 4ac3b61c18b651f396fe8a59a25f2bca 253 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 95 115 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 DFR86_00595 4ac3b61c18b651f396fe8a59a25f2bca 253 SUPERFAMILY SSF52096 1 252 1.33E-89 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR86_00595 4ac3b61c18b651f396fe8a59a25f2bca 253 Gene3D G3DSA:1.10.12.10 197 253 2.9E-23 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal DFR86_00595 4ac3b61c18b651f396fe8a59a25f2bca 253 Gene3D G3DSA:3.90.226.10 2 196 1.6E-73 T 31-10-2018 DFR86_00595 4ac3b61c18b651f396fe8a59a25f2bca 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 252 4.6E-80 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR86_00425 48d1aa3cf061144a5f119ead0cc03001 405 SMART SM00933 61 366 9.8E-20 T 31-10-2018 IPR018977 NurA domain DFR86_00425 48d1aa3cf061144a5f119ead0cc03001 405 Pfam PF09376 NurA domain 62 365 1.1E-16 T 31-10-2018 IPR018977 NurA domain DFR86_11635 3944ce95429215a11dfb4dde602d9191 110 Pfam PF01867 CRISPR associated protein Cas1 6 106 1.5E-7 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR86_06400 372b871ab7e6ec438539055bb0b83702 308 Gene3D G3DSA:3.10.129.10 2 147 9.6E-27 T 31-10-2018 DFR86_06400 372b871ab7e6ec438539055bb0b83702 308 Gene3D G3DSA:3.10.129.10 157 305 6.3E-32 T 31-10-2018 DFR86_06400 372b871ab7e6ec438539055bb0b83702 308 Pfam PF03061 Thioesterase superfamily 170 240 6.0E-12 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR86_06400 372b871ab7e6ec438539055bb0b83702 308 Pfam PF03061 Thioesterase superfamily 19 93 3.0E-9 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR86_06400 372b871ab7e6ec438539055bb0b83702 308 SUPERFAMILY SSF54637 9 146 1.14E-25 T 31-10-2018 IPR029069 HotDog domain superfamily DFR86_06400 372b871ab7e6ec438539055bb0b83702 308 SUPERFAMILY SSF54637 160 303 2.55E-30 T 31-10-2018 IPR029069 HotDog domain superfamily DFR86_03970 89cabf8445767774c9ab7c59c05f81a2 232 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 1 212 1.0E-31 T 31-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 DFR86_03970 89cabf8445767774c9ab7c59c05f81a2 232 Gene3D G3DSA:3.40.50.300 1 214 7.0E-29 T 31-10-2018 DFR86_03970 89cabf8445767774c9ab7c59c05f81a2 232 SUPERFAMILY SSF52540 2 197 1.15E-20 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_03695 b32834652a3c2345b16cfdb0e1d3126f 285 Pfam PF01925 Sulfite exporter TauE/SafE 9 277 3.6E-44 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 DFR86_01725 097eca0252cab1a59ad083a234d67049 378 Pfam PF00266 Aminotransferase class-V 24 325 4.2E-39 T 31-10-2018 IPR000192 Aminotransferase class V domain DFR86_01725 097eca0252cab1a59ad083a234d67049 378 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 177 197 - T 31-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site DFR86_01725 097eca0252cab1a59ad083a234d67049 378 Gene3D G3DSA:3.40.640.10 9 257 4.4E-109 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_01725 097eca0252cab1a59ad083a234d67049 378 SUPERFAMILY SSF53383 2 361 2.36E-92 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_01725 097eca0252cab1a59ad083a234d67049 378 PIRSF PIRSF000524 1 378 5.7E-93 T 31-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 DFR86_01725 097eca0252cab1a59ad083a234d67049 378 Gene3D G3DSA:3.90.1150.10 4 370 4.4E-109 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_02130 a56facf9d74f880914b2de5289812e67 331 Pfam PF12698 ABC-2 family transporter protein 21 318 2.7E-11 T 31-10-2018 DFR86_05140 ffa480f6d2915b6b774f267d420555ee 406 PRINTS PR00758 Arsenical pump membrane protein signature 100 124 3.0E-6 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR86_05140 ffa480f6d2915b6b774f267d420555ee 406 PRINTS PR00758 Arsenical pump membrane protein signature 267 291 3.0E-6 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR86_05140 ffa480f6d2915b6b774f267d420555ee 406 Pfam PF03600 Citrate transporter 22 346 2.0E-34 T 31-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 DFR86_08875 0bbf590904bfef085618f56ba3abf91c 271 Gene3D G3DSA:3.40.50.970 9 268 1.3E-78 T 31-10-2018 DFR86_08875 0bbf590904bfef085618f56ba3abf91c 271 SUPERFAMILY SSF52518 9 257 1.98E-72 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR86_08875 0bbf590904bfef085618f56ba3abf91c 271 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 36 256 2.6E-32 T 31-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 DFR86_10785 1a5c59b9463696fd65a367085c9c2315 305 Pfam PF02754 Cysteine-rich domain 10 92 2.5E-16 T 31-10-2018 IPR004017 Cysteine-rich domain DFR86_10785 1a5c59b9463696fd65a367085c9c2315 305 Pfam PF02754 Cysteine-rich domain 157 246 2.6E-10 T 31-10-2018 IPR004017 Cysteine-rich domain DFR86_04560 3329c796cc6b575e6931c509913c55f8 443 Pfam PF00324 Amino acid permease 22 409 1.2E-24 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR86_04560 3329c796cc6b575e6931c509913c55f8 443 Gene3D G3DSA:1.20.1740.10 11 443 1.3E-37 T 31-10-2018 DFR86_04560 3329c796cc6b575e6931c509913c55f8 443 PIRSF PIRSF006060 1 442 2.8E-59 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_05285 8c5aab09b427734d4bed29add9eb6c94 195 Gene3D G3DSA:3.40.50.1820 1 128 1.9E-29 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_05285 8c5aab09b427734d4bed29add9eb6c94 195 SUPERFAMILY SSF53474 3 194 4.67E-40 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_05285 8c5aab09b427734d4bed29add9eb6c94 195 Pfam PF00561 alpha/beta hydrolase fold 24 121 3.4E-14 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR86_05285 8c5aab09b427734d4bed29add9eb6c94 195 Gene3D G3DSA:3.40.50.1820 129 193 5.3E-9 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_00800 9f75098c3bc85aaa02811b413533f5e1 261 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 36 239 6.6E-12 T 31-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 DFR86_00800 9f75098c3bc85aaa02811b413533f5e1 261 SUPERFAMILY SSF53213 20 257 1.6E-13 T 31-10-2018 DFR86_00800 9f75098c3bc85aaa02811b413533f5e1 261 Gene3D G3DSA:3.40.830.10 2 261 2.4E-58 T 31-10-2018 DFR86_04605 53819e19082adaa0fd50100a14464b88 400 SUPERFAMILY SSF53901 5 228 1.82E-43 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_04605 53819e19082adaa0fd50100a14464b88 400 Pfam PF02803 Thiolase, C-terminal domain 279 366 6.1E-7 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 DFR86_04605 53819e19082adaa0fd50100a14464b88 400 SUPERFAMILY SSF53901 233 366 4.4E-24 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_04605 53819e19082adaa0fd50100a14464b88 400 Gene3D G3DSA:3.40.47.10 4 394 8.1E-116 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR86_04605 53819e19082adaa0fd50100a14464b88 400 PIRSF PIRSF000429 1 391 2.1E-58 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR86_04605 53819e19082adaa0fd50100a14464b88 400 Pfam PF00108 Thiolase, N-terminal domain 5 224 6.6E-21 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR86_01135 8035eb9924455d92bd18027e26646f75 137 Pfam PF11485 Protein of unknown function (DUF3211) 1 137 1.4E-45 T 31-10-2018 IPR021578 Protein of unknown function DUF3211 DFR86_01135 8035eb9924455d92bd18027e26646f75 137 Gene3D G3DSA:3.30.530.20 1 137 1.6E-48 T 31-10-2018 IPR023393 START-like domain superfamily DFR86_10810 460dd0e44ae7d130d8b2cb8048c80e20 67 Pfam PF06348 Protein of unknown function (DUF1059) 11 66 8.5E-23 T 31-10-2018 IPR009409 Protein of unknown function DUF1059 DFR86_02080 8be8b4427e7f352aa21043187c1e650d 219 Pfam PF13614 AAA domain 2 151 7.5E-28 T 31-10-2018 IPR025669 AAA domain DFR86_02080 8be8b4427e7f352aa21043187c1e650d 219 Gene3D G3DSA:3.40.50.300 1 216 1.9E-37 T 31-10-2018 DFR86_02080 8be8b4427e7f352aa21043187c1e650d 219 SUPERFAMILY SSF52540 1 213 7.45E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_08365 3b375d15d373ec8a1fff9582454f9f4d 210 Pfam PF04055 Radical SAM superfamily 29 159 3.4E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_08365 3b375d15d373ec8a1fff9582454f9f4d 210 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 210 33.692 T 31-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 DFR86_08365 3b375d15d373ec8a1fff9582454f9f4d 210 PIRSF PIRSF000370 2 210 1.1E-47 T 31-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 DFR86_08365 3b375d15d373ec8a1fff9582454f9f4d 210 SUPERFAMILY SSF102114 30 171 1.44E-15 T 31-10-2018 DFR86_08365 3b375d15d373ec8a1fff9582454f9f4d 210 Gene3D G3DSA:3.20.20.70 3 210 8.7E-42 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_08365 3b375d15d373ec8a1fff9582454f9f4d 210 Pfam PF13394 4Fe-4S single cluster domain 26 124 6.7E-13 T 31-10-2018 DFR86_01440 715dc1e3f1c6e122d309c3103f83a505 737 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 278 293 5.6E-9 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR86_01440 715dc1e3f1c6e122d309c3103f83a505 737 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 172 187 5.6E-9 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR86_01440 715dc1e3f1c6e122d309c3103f83a505 737 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 297 309 5.6E-9 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR86_01440 715dc1e3f1c6e122d309c3103f83a505 737 Gene3D G3DSA:1.25.10.10 479 656 8.9E-16 T 31-10-2018 IPR011989 Armadillo-like helical DFR86_01440 715dc1e3f1c6e122d309c3103f83a505 737 SUPERFAMILY SSF48371 536 719 1.02E-17 T 31-10-2018 IPR016024 Armadillo-type fold DFR86_01440 715dc1e3f1c6e122d309c3103f83a505 737 Gene3D G3DSA:2.60.40.1730 23 189 4.2E-20 T 31-10-2018 DFR86_01440 715dc1e3f1c6e122d309c3103f83a505 737 SUPERFAMILY SSF63737 14 188 2.62E-19 T 31-10-2018 DFR86_01440 715dc1e3f1c6e122d309c3103f83a505 737 Gene3D G3DSA:1.10.390.60 194 427 1.8E-62 T 31-10-2018 DFR86_01440 715dc1e3f1c6e122d309c3103f83a505 737 SUPERFAMILY SSF55486 196 434 6.15E-68 T 31-10-2018 DFR86_01440 715dc1e3f1c6e122d309c3103f83a505 737 Pfam PF01433 Peptidase family M1 domain 199 422 1.0E-46 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR86_02530 d16d2075192870aed9e2503119e17971 322 Gene3D G3DSA:3.60.21.10 73 320 2.5E-22 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR86_02530 d16d2075192870aed9e2503119e17971 322 SUPERFAMILY SSF56300 15 319 5.47E-73 T 31-10-2018 DFR86_05650 f03fe28ecd107e0595d9203199b22d46 402 Gene3D G3DSA:3.40.640.10 67 292 5.7E-140 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR86_05650 f03fe28ecd107e0595d9203199b22d46 402 Gene3D G3DSA:3.90.1150.10 20 397 5.7E-140 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR86_05650 f03fe28ecd107e0595d9203199b22d46 402 Pfam PF00155 Aminotransferase class I and II 60 378 1.2E-39 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR86_05650 f03fe28ecd107e0595d9203199b22d46 402 SUPERFAMILY SSF53383 4 398 7.93E-108 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR86_02990 255023f9d9f9e18822e1ae71787ca5e8 194 Pfam PF12804 MobA-like NTP transferase domain 5 157 2.0E-34 T 31-10-2018 IPR025877 MobA-like NTP transferase DFR86_02990 255023f9d9f9e18822e1ae71787ca5e8 194 Gene3D G3DSA:3.90.550.10 2 179 1.5E-50 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_02990 255023f9d9f9e18822e1ae71787ca5e8 194 SUPERFAMILY SSF53448 1 181 5.01E-30 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_08145 d3526032131b3bbeb0225eb180d1ae2c 384 Gene3D G3DSA:3.90.25.10 210 369 6.5E-152 T 31-10-2018 DFR86_08145 d3526032131b3bbeb0225eb180d1ae2c 384 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 358 1.9E-26 T 31-10-2018 IPR016040 NAD(P)-binding domain DFR86_08145 d3526032131b3bbeb0225eb180d1ae2c 384 SUPERFAMILY SSF51735 1 369 2.12E-55 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR86_08145 d3526032131b3bbeb0225eb180d1ae2c 384 Gene3D G3DSA:3.40.50.720 2 293 6.5E-152 T 31-10-2018 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 Gene3D G3DSA:1.20.210.10 11 489 2.7E-70 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 12 456 1.8E-67 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 229 283 - T 31-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 SUPERFAMILY SSF81442 8 488 1.7E-70 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 248 6.1E-20 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 380 6.1E-20 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 PRINTS PR01165 Cytochrome c oxidase subunit I signature 53 76 6.1E-20 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 PRINTS PR01165 Cytochrome c oxidase subunit I signature 273 288 6.1E-20 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 PRINTS PR01165 Cytochrome c oxidase subunit I signature 333 351 6.1E-20 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 PRINTS PR01165 Cytochrome c oxidase subunit I signature 415 436 6.1E-20 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_03940 50bea8b9a4412ec728c980fdf86562b7 561 PRINTS PR01165 Cytochrome c oxidase subunit I signature 297 318 6.1E-20 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR86_04850 2eda96c161a7ee7d2713876e68c6d369 584 Pfam PF00326 Prolyl oligopeptidase family 384 583 1.3E-41 T 31-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DFR86_04850 2eda96c161a7ee7d2713876e68c6d369 584 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 443 463 6.7E-33 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 DFR86_04850 2eda96c161a7ee7d2713876e68c6d369 584 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 417 436 6.7E-33 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 DFR86_04850 2eda96c161a7ee7d2713876e68c6d369 584 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 389 413 6.7E-33 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 DFR86_04850 2eda96c161a7ee7d2713876e68c6d369 584 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 363 381 6.7E-33 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 DFR86_04850 2eda96c161a7ee7d2713876e68c6d369 584 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 515 537 6.7E-33 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 DFR86_04850 2eda96c161a7ee7d2713876e68c6d369 584 SUPERFAMILY SSF53474 349 581 4.48E-37 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_04850 2eda96c161a7ee7d2713876e68c6d369 584 Gene3D G3DSA:3.40.50.1820 306 583 5.9E-57 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR86_10385 5eac6168fe04c4123be06b99600dc877 803 Gene3D G3DSA:3.40.50.200 1 61 1.3E-6 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR86_10385 5eac6168fe04c4123be06b99600dc877 803 Gene3D G3DSA:2.60.40.10 631 721 5.3E-7 T 31-10-2018 IPR013783 Immunoglobulin-like fold DFR86_10385 5eac6168fe04c4123be06b99600dc877 803 SUPERFAMILY SSF52743 2 56 3.17E-5 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR86_00390 93a39c3752e8ccabfe627fe1f1277371 275 Pfam PF02673 Bacitracin resistance protein BacA 8 263 4.1E-50 T 31-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 DFR86_00390 93a39c3752e8ccabfe627fe1f1277371 275 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 272 14.557 T 31-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 DFR86_03945 014b90b2a10a309280d9486ee04aabb7 187 Pfam PF07185 Protein of unknown function (DUF1404) 16 182 3.5E-59 T 31-10-2018 IPR009844 Protein of unknown function DUF1404 DFR86_06840 39734c60718a0815725c4a0b015eb993 54 Gene3D G3DSA:4.10.830.10 5 54 7.7E-18 T 31-10-2018 DFR86_06840 39734c60718a0815725c4a0b015eb993 54 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 54 15.753 T 31-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 DFR86_06840 39734c60718a0815725c4a0b015eb993 54 ProSitePatterns PS00527 Ribosomal protein S14 signature. 20 42 - T 31-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_06840 39734c60718a0815725c4a0b015eb993 54 Pfam PF00253 Ribosomal protein S14p/S29e 7 52 3.1E-8 T 31-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR86_06110 e1fab4dcd051ea8abbe579e9ad9f84ab 254 Pfam PF09973 Predicted membrane protein (DUF2208) 12 240 4.7E-61 T 31-10-2018 IPR009198 Uncharacterised conserved protein UCP014484, transmembrane DFR86_04790 c205adbfc7d6ff8fd87346f13df9494b 300 Pfam PF02754 Cysteine-rich domain 201 286 8.9E-7 T 31-10-2018 IPR004017 Cysteine-rich domain DFR86_00930 57345effa2cd1204fdadc17b4c2a1714 298 Pfam PF00535 Glycosyl transferase family 2 5 126 2.6E-30 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_00930 57345effa2cd1204fdadc17b4c2a1714 298 SUPERFAMILY SSF53448 1 277 1.29E-47 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_00930 57345effa2cd1204fdadc17b4c2a1714 298 Gene3D G3DSA:3.90.550.10 1 221 3.1E-46 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_10500 e62c36f137bb50f329960f8f66813c66 329 Pfam PF02361 Cobalt transport protein 52 285 4.2E-12 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component DFR86_04940 31030c45143aac82a331bf5597b95754 247 Pfam PF13240 zinc-ribbon domain 3 23 2.2E-6 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR86_06215 e4cec113990a11f8d2706f82c3288b90 156 Gene3D G3DSA:3.10.690.10 73 155 1.6E-8 T 31-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 DFR86_06215 e4cec113990a11f8d2706f82c3288b90 156 SUPERFAMILY SSF103256 8 151 2.09E-26 T 31-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 DFR86_06215 e4cec113990a11f8d2706f82c3288b90 156 Pfam PF02577 Bifunctional nuclease 79 146 4.8E-9 T 31-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 DFR86_00345 6b740639931ab66f43452955e7383dc4 136 Gene3D G3DSA:3.30.1460.10 2 136 4.4E-19 T 31-10-2018 DFR86_00345 6b740639931ab66f43452955e7383dc4 136 Pfam PF10061 Uncharacterized conserved protein (DUF2299) 8 133 1.7E-36 T 31-10-2018 IPR018747 Protein of unknown function DUF2299 DFR86_03485 0aee6329e34448e7735101f15489932c 1150 Pfam PF03176 MMPL family 961 1141 8.2E-32 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 DFR86_03485 0aee6329e34448e7735101f15489932c 1150 Pfam PF03176 MMPL family 606 796 4.5E-27 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 DFR86_03485 0aee6329e34448e7735101f15489932c 1150 SUPERFAMILY SSF82866 983 1143 1.83E-21 T 31-10-2018 DFR86_03485 0aee6329e34448e7735101f15489932c 1150 SUPERFAMILY SSF82866 632 789 2.75E-24 T 31-10-2018 DFR86_04080 7207d267c7b3f5ae4c079866a0edcec9 173 Pfam PF07680 TQO small subunit DoxA 29 161 2.6E-38 T 31-10-2018 IPR011636 Thiosulphate:quinone oxidoreductase small subunit DoxA KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 DFR86_06430 1ffebafca631635a99c51c840200ceda 165 Hamap MF_01116 Probable ribosome biogenesis protein . 1 162 31.157 T 31-10-2018 IPR022968 Ribosome biogenesis protein Reactome: R-HSA-6790901 DFR86_06430 1ffebafca631635a99c51c840200ceda 165 Pfam PF04034 Ribosome biogenesis protein, C-terminal 36 161 5.1E-40 T 31-10-2018 IPR007177 Ribosome biogenesis protein, C-terminal Reactome: R-HSA-6790901 DFR86_06430 1ffebafca631635a99c51c840200ceda 165 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 2 28 3.2E-9 T 31-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain DFR86_06430 1ffebafca631635a99c51c840200ceda 165 ProDom PD016638 UPF0293 SIMILAR RNASE YOR006C RNA COMPONENT SACCHAROMYCES P RIKEN CERVISIAE 36 159 2.0E-31 T 31-10-2018 IPR007177 Ribosome biogenesis protein, C-terminal Reactome: R-HSA-6790901 DFR86_01240 afcc3bed8a5599ca0706255696bde2f4 477 SUPERFAMILY SSF103473 23 472 2.75E-64 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_01240 afcc3bed8a5599ca0706255696bde2f4 477 Pfam PF00083 Sugar (and other) transporter 37 472 2.5E-32 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR86_01240 afcc3bed8a5599ca0706255696bde2f4 477 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR86_01240 afcc3bed8a5599ca0706255696bde2f4 477 Gene3D G3DSA:1.20.1250.20 24 475 4.1E-61 T 31-10-2018 DFR86_06060 f497572e29132604bfbc4e0fdef92ec7 141 SUPERFAMILY SSF88723 9 134 1.49E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR86_06060 f497572e29132604bfbc4e0fdef92ec7 141 SMART SM00670 7 116 1.3E-4 T 31-10-2018 IPR002716 PIN domain DFR86_06060 f497572e29132604bfbc4e0fdef92ec7 141 Gene3D G3DSA:3.40.50.1010 8 137 3.3E-18 T 31-10-2018 DFR86_02260 c78e6ae9e261903a6ea905115661790b 119 PIRSF PIRSF016498 1 119 1.1E-42 T 31-10-2018 IPR018699 Protein of unknown function DUF2203 DFR86_02260 c78e6ae9e261903a6ea905115661790b 119 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 3 109 7.6E-28 T 31-10-2018 IPR018699 Protein of unknown function DUF2203 DFR86_10230 1f221d03459ac40746bad887c028d991 313 Pfam PF01699 Sodium/calcium exchanger protein 6 148 1.6E-20 T 31-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 DFR86_10230 1f221d03459ac40746bad887c028d991 313 Pfam PF01699 Sodium/calcium exchanger protein 175 311 5.4E-12 T 31-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 DFR86_10230 1f221d03459ac40746bad887c028d991 313 Gene3D G3DSA:1.20.58.1130 11 203 6.5E-39 T 31-10-2018 DFR86_10230 1f221d03459ac40746bad887c028d991 313 Gene3D G3DSA:1.20.1420.30 36 303 6.5E-39 T 31-10-2018 DFR86_11620 ff45bbc5852e2c123ff900933ce000f8 297 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 72 267 1.3E-36 T 31-10-2018 IPR010172 CRISPR-associated protein, TM1791 DFR86_11620 ff45bbc5852e2c123ff900933ce000f8 297 Pfam PF03787 RAMP superfamily 101 268 2.8E-9 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_00795 6031e2e3c717546636bcb25e3bd8271d 427 Pfam PF13173 AAA domain 39 161 3.1E-28 T 31-10-2018 DFR86_00795 6031e2e3c717546636bcb25e3bd8271d 427 SUPERFAMILY SSF52540 18 211 1.16E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00795 6031e2e3c717546636bcb25e3bd8271d 427 Pfam PF13635 Domain of unknown function (DUF4143) 232 348 9.5E-11 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 DFR86_01535 ea6d24141f02225af5a845da40698d28 936 Pfam PF05317 Thermopsin 144 394 3.6E-56 T 31-10-2018 IPR007981 Peptidase A5, thermopsin DFR86_00310 449f6c25c79521158c9c3396ada7339f 355 Pfam PF03916 Polysulphide reductase, NrfD 28 262 1.8E-7 T 31-10-2018 IPR005614 NrfD family DFR86_06960 f05b205381f72e4b00d4aa771776921d 137 Gene3D G3DSA:3.60.21.10 1 136 1.1E-6 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR86_06960 f05b205381f72e4b00d4aa771776921d 137 SUPERFAMILY SSF56300 2 133 8.02E-19 T 31-10-2018 DFR86_02755 16fc050491859a1a9404788dc83906e9 446 SUPERFAMILY SSF88713 8 343 1.17E-56 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DFR86_02755 16fc050491859a1a9404788dc83906e9 446 Pfam PF03065 Glycosyl hydrolase family 57 9 321 6.6E-72 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 DFR86_02755 16fc050491859a1a9404788dc83906e9 446 Gene3D G3DSA:3.20.110.20 30 345 3.2E-26 T 31-10-2018 DFR86_04985 6828d98bb29ed022c2786c029dfd19e7 205 Gene3D G3DSA:3.40.50.300 1 204 5.9E-30 T 31-10-2018 DFR86_04985 6828d98bb29ed022c2786c029dfd19e7 205 SUPERFAMILY SSF52540 2 203 3.86E-24 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_04985 6828d98bb29ed022c2786c029dfd19e7 205 Pfam PF02223 Thymidylate kinase 5 141 5.6E-13 T 31-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DFR86_02150 93d9a4155f9fd3ef60482579cea9e48f 118 SUPERFAMILY SSF53146 1 96 4.19E-5 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily DFR86_07830 0d6bf09c6bada2e17e3b04b9365ba565 125 Gene3D G3DSA:3.40.1260.10 1 122 1.3E-16 T 31-10-2018 IPR027396 DsrEFH-like DFR86_07830 0d6bf09c6bada2e17e3b04b9365ba565 125 SUPERFAMILY SSF75169 1 110 3.03E-15 T 31-10-2018 IPR027396 DsrEFH-like DFR86_07830 0d6bf09c6bada2e17e3b04b9365ba565 125 Pfam PF02635 DsrE/DsrF-like family 1 113 1.1E-11 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR86_08700 aabe008c3593b7ebcf84a7302fadc724 147 Pfam PF10051 Uncharacterized protein conserved in archaea (DUF2286) 2 135 2.5E-50 T 31-10-2018 IPR017006 Uncharacterised conserved protein UCP032756 DFR86_08700 aabe008c3593b7ebcf84a7302fadc724 147 PIRSF PIRSF032756 1 146 2.9E-57 T 31-10-2018 IPR017006 Uncharacterised conserved protein UCP032756 DFR86_09385 068f9ee9d6da86ea7f2c26dbb4a610b2 227 SUPERFAMILY SSF159659 2 214 5.23E-41 T 31-10-2018 DFR86_09385 068f9ee9d6da86ea7f2c26dbb4a610b2 227 Gene3D G3DSA:3.40.50.10900 1 221 9.2E-51 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily DFR86_09385 068f9ee9d6da86ea7f2c26dbb4a610b2 227 Pfam PF09754 PAC2 family 2 207 3.0E-40 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 DFR86_10415 2ba44e34744487c02aada147e345c5d3 648 Pfam PF01968 Hydantoinase/oxoprolinase 193 482 1.8E-96 T 31-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 DFR86_10415 2ba44e34744487c02aada147e345c5d3 648 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 174 4.9E-52 T 31-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 DFR86_04615 ed84ec988d2d5ccca0897a93e65bd794 239 Gene3D G3DSA:3.20.20.70 10 235 1.9E-44 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_04615 ed84ec988d2d5ccca0897a93e65bd794 239 Pfam PF05913 Bacterial protein of unknown function (DUF871) 13 235 3.2E-43 T 31-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic DFR86_04615 ed84ec988d2d5ccca0897a93e65bd794 239 SUPERFAMILY SSF51445 10 235 1.75E-38 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR86_01175 9b6dde80893dd59a694a8a0d1509e804 82 Pfam PF01294 Ribosomal protein L13e 5 72 5.4E-13 T 31-10-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_01175 9b6dde80893dd59a694a8a0d1509e804 82 Hamap MF_00499 50S ribosomal protein L13e [rpl13e]. 1 79 20.388 T 31-10-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_01175 9b6dde80893dd59a694a8a0d1509e804 82 ProSitePatterns PS01104 Ribosomal protein L13e signature. 25 39 - T 31-10-2018 IPR018256 Ribosomal protein L13e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_01715 07dbaa36b3915f30836e2888e8f5c05d 221 Pfam PF12916 Protein of unknown function (DUF3834) 1 202 2.4E-57 T 31-10-2018 IPR024533 Protein of unknown function DUF3834 DFR86_01715 07dbaa36b3915f30836e2888e8f5c05d 221 SUPERFAMILY SSF53850 48 180 1.18E-7 T 31-10-2018 DFR86_01715 07dbaa36b3915f30836e2888e8f5c05d 221 Gene3D G3DSA:3.40.190.200 3 196 1.4E-26 T 31-10-2018 DFR86_06190 8e6f6b7f8bb4296230449edfdee91bfb 96 Gene3D G3DSA:2.30.30.30 2 87 1.3E-36 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR86_06190 8e6f6b7f8bb4296230449edfdee91bfb 96 SUPERFAMILY SSF50104 2 90 1.2E-24 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR86_06190 8e6f6b7f8bb4296230449edfdee91bfb 96 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 80 27.302 T 31-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 DFR86_08800 c46e7a85a6f73ec3f8d1c307a82378ec 72 Gene3D G3DSA:3.30.110.40 1 70 8.1E-6 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_08800 c46e7a85a6f73ec3f8d1c307a82378ec 72 SUPERFAMILY SSF64307 1 70 4.58E-9 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_10845 2207ebff38211514bc4b126c9aadc9ac 349 SMART SM00729 36 263 4.3E-20 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR86_10845 2207ebff38211514bc4b126c9aadc9ac 349 SUPERFAMILY SSF102114 35 266 8.76E-32 T 31-10-2018 DFR86_10845 2207ebff38211514bc4b126c9aadc9ac 349 Pfam PF04055 Radical SAM superfamily 44 218 8.5E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR86_10845 2207ebff38211514bc4b126c9aadc9ac 349 Gene3D G3DSA:3.20.20.70 30 272 2.0E-21 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_09605 6ef9e1ac00232b71f377983af1aefb2f 410 Pfam PF04894 Archaeal Nre, N-terminal 18 289 2.6E-96 T 31-10-2018 IPR006978 Archaeal Nre, N-terminal DFR86_09605 6ef9e1ac00232b71f377983af1aefb2f 410 Hamap MF_02096 DNA repair protein. 1 404 35.911 T 31-10-2018 IPR033167 Archaeal Nre GO:0006281 DFR86_09605 6ef9e1ac00232b71f377983af1aefb2f 410 Pfam PF04895 Archaeal Nre, C-terminal 304 404 1.1E-33 T 31-10-2018 IPR006979 Archaeal Nre, C-terminal DFR86_04425 9537aaf5d21edd824490df4d41a3cd9c 157 Pfam PF08909 Domain of unknown function (DUF1854) 36 155 2.3E-21 T 31-10-2018 IPR015005 Domain of unknown function DUF1854 DFR86_11270 e580df8088444b8e27d04a8e19172c48 496 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 448 1.1E-76 T 31-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 DFR86_01000 9627d316eb4256b5b477546d9d8c1c2e 288 Gene3D G3DSA:3.40.50.300 94 287 6.3E-7 T 31-10-2018 DFR86_07585 820f7a13feb3a4eacaba0b2c82c2cfaf 131 ProSitePatterns PS01318 TsaA-like domain signature. 66 77 - T 31-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site DFR86_07585 820f7a13feb3a4eacaba0b2c82c2cfaf 131 SUPERFAMILY SSF118196 2 129 4.18E-39 T 31-10-2018 IPR036413 YaeB-like superfamily DFR86_07585 820f7a13feb3a4eacaba0b2c82c2cfaf 131 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 15 114 1.2E-32 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain DFR86_07585 820f7a13feb3a4eacaba0b2c82c2cfaf 131 Pfam PF01980 Uncharacterised protein family UPF0066 18 113 1.0E-31 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain DFR86_07585 820f7a13feb3a4eacaba0b2c82c2cfaf 131 Gene3D G3DSA:2.40.30.70 3 130 1.9E-33 T 31-10-2018 IPR036414 YaeB, N-terminal domain superfamily DFR86_06765 42a1ffdb46127e06271144793fedcd46 246 Gene3D G3DSA:2.40.50.140 97 147 1.2E-30 T 31-10-2018 DFR86_06765 42a1ffdb46127e06271144793fedcd46 246 SUPERFAMILY SSF75217 6 245 3.92E-25 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases DFR86_06765 42a1ffdb46127e06271144793fedcd46 246 Gene3D G3DSA:3.40.1280.10 12 242 1.2E-30 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DFR86_06765 42a1ffdb46127e06271144793fedcd46 246 Pfam PF02598 Putative RNA methyltransferase 10 98 2.2E-7 T 31-10-2018 IPR003750 Putative RNA methyltransferase DFR86_06765 42a1ffdb46127e06271144793fedcd46 246 Pfam PF02598 Putative RNA methyltransferase 147 241 7.5E-5 T 31-10-2018 IPR003750 Putative RNA methyltransferase DFR86_07965 0ff92b94251766d239f7e0f0389b1acf 264 Pfam PF01435 Peptidase family M48 64 263 2.5E-22 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DFR86_07965 0ff92b94251766d239f7e0f0389b1acf 264 Gene3D G3DSA:3.30.2010.10 55 145 1.1E-16 T 31-10-2018 DFR86_05205 f0f5662f9cc069ea807e12aaf371e052 91 Pfam PF01998 Protein of unknown function DUF131 29 82 5.4E-19 T 31-10-2018 IPR002849 Protein of unknown function DUF131 DFR86_05205 f0f5662f9cc069ea807e12aaf371e052 91 TIGRFAM TIGR00304 TIGR00304: TIGR00304 family protein 4 80 1.8E-19 T 31-10-2018 IPR002849 Protein of unknown function DUF131 DFR86_04215 267dfac4e543aff52e5656bd33557e14 414 Gene3D G3DSA:3.20.20.140 53 352 6.2E-106 T 31-10-2018 DFR86_04215 267dfac4e543aff52e5656bd33557e14 414 SUPERFAMILY SSF51556 52 362 7.94E-67 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR86_04215 267dfac4e543aff52e5656bd33557e14 414 SUPERFAMILY SSF51338 5 64 7.97E-7 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_04215 267dfac4e543aff52e5656bd33557e14 414 Pfam PF07969 Amidohydrolase family 178 391 4.6E-17 T 31-10-2018 IPR013108 Amidohydrolase 3 DFR86_04215 267dfac4e543aff52e5656bd33557e14 414 Gene3D G3DSA:2.30.40.10 9 393 6.2E-106 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR86_09550 cdd7a9462fa729469a0e657ab189288d 90 SUPERFAMILY SSF54975 2 88 1.57E-27 T 31-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR86_09550 cdd7a9462fa729469a0e657ab189288d 90 ProSitePatterns PS00151 Acylphosphatase signature 2. 33 49 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR86_09550 cdd7a9462fa729469a0e657ab189288d 90 PRINTS PR00112 Acylphosphatase signature 4 19 2.8E-5 T 31-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR86_09550 cdd7a9462fa729469a0e657ab189288d 90 PRINTS PR00112 Acylphosphatase signature 25 50 2.8E-5 T 31-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR86_09550 cdd7a9462fa729469a0e657ab189288d 90 Gene3D G3DSA:3.30.70.100 1 90 9.2E-36 T 31-10-2018 DFR86_09550 cdd7a9462fa729469a0e657ab189288d 90 Pfam PF00708 Acylphosphatase 6 88 2.8E-27 T 31-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR86_09550 cdd7a9462fa729469a0e657ab189288d 90 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR86_11645 6e63b81192689beff6d70f422db052c1 279 Gene3D G3DSA:3.30.70.1900 133 279 3.2E-18 T 31-10-2018 DFR86_11645 6e63b81192689beff6d70f422db052c1 279 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 149 274 3.8E-10 T 31-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal DFR86_03335 840820c1d46a0be1f773034cb4199097 548 Pfam PF09843 Predicted membrane protein (DUF2070) 32 535 3.6E-87 T 31-10-2018 IPR019204 Domain of unknown function DUF2070, membrane DFR86_11400 4f7c7373e06d64ffc1181f6ffe255fd8 249 Pfam PF03787 RAMP superfamily 18 230 2.7E-22 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_04815 95f19ddb8d88425b0f5be971ab7c1b51 186 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 10 151 2.3E-8 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 DFR86_04815 95f19ddb8d88425b0f5be971ab7c1b51 186 Gene3D G3DSA:3.60.21.10 6 185 6.1E-18 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR86_04815 95f19ddb8d88425b0f5be971ab7c1b51 186 SUPERFAMILY SSF56300 10 166 1.49E-15 T 31-10-2018 DFR86_03455 72bf6888d8408908b0aa1d03387f5116 270 Pfam PF01061 ABC-2 type transporter 22 224 2.1E-13 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 DFR86_04515 02835d873c3aee1ed6069bd18ab958d3 345 Gene3D G3DSA:1.10.3720.10 112 340 1.0E-15 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_04515 02835d873c3aee1ed6069bd18ab958d3 345 SUPERFAMILY SSF161098 118 331 2.62E-11 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_04515 02835d873c3aee1ed6069bd18ab958d3 345 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 343 5.4E-35 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_06510 2177657cbdd6bc04d7cf6739f7536756 128 SUPERFAMILY SSF53032 38 125 5.76E-12 T 31-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR86_06510 2177657cbdd6bc04d7cf6739f7536756 128 Gene3D G3DSA:3.40.1350.10 37 127 1.8E-13 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 DFR86_05490 c658be47d208f12186fef11c4d456951 232 SUPERFAMILY SSF53335 41 223 1.03E-20 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR86_05490 c658be47d208f12186fef11c4d456951 232 Pfam PF08241 Methyltransferase domain 87 176 7.8E-17 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR86_05490 c658be47d208f12186fef11c4d456951 232 Gene3D G3DSA:3.40.50.150 21 224 2.4E-22 T 31-10-2018 DFR86_04125 dfe7933f5e6683bf3f1cc0da1f6684ce 309 SUPERFAMILY SSF56300 5 287 2.34E-65 T 31-10-2018 DFR86_04125 dfe7933f5e6683bf3f1cc0da1f6684ce 309 Pfam PF00149 Calcineurin-like phosphoesterase 6 253 5.3E-10 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR86_04125 dfe7933f5e6683bf3f1cc0da1f6684ce 309 Gene3D G3DSA:3.60.21.10 83 291 2.8E-26 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR86_07815 68a300219e034f64a643a030966f1924 464 Gene3D G3DSA:3.90.650.10 219 455 8.1E-15 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_07815 68a300219e034f64a643a030966f1924 464 SUPERFAMILY SSF56042 332 446 2.93E-8 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR86_05905 16aa6ffe60ae5032acecfaf0bd954644 48 SMART SM00659 3 48 3.1E-13 T 31-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR86_05905 16aa6ffe60ae5032acecfaf0bd954644 48 SUPERFAMILY SSF63393 3 47 1.2E-11 T 31-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 DFR86_05905 16aa6ffe60ae5032acecfaf0bd954644 48 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 4 48 14.916 T 31-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR86_05905 16aa6ffe60ae5032acecfaf0bd954644 48 Gene3D G3DSA:2.20.28.30 1 48 4.5E-20 T 31-10-2018 DFR86_04350 da496f78f8e3a4e4944463c5345e19eb 196 Pfam PF01774 UreD urease accessory protein 39 149 3.3E-11 T 31-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 DFR86_00250 f4da09e827a67b4cc31d4437ec960bb9 383 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 245 325 4.2E-17 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_00250 f4da09e827a67b4cc31d4437ec960bb9 383 Pfam PF07282 Putative transposase DNA-binding domain 298 364 1.4E-21 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_07400 32a8f886cace2aa0b156cc18e18a89de 335 Gene3D G3DSA:1.20.1250.20 3 179 3.7E-11 T 31-10-2018 DFR86_07400 32a8f886cace2aa0b156cc18e18a89de 335 SUPERFAMILY SSF103473 5 174 4.45E-12 T 31-10-2018 IPR036259 MFS transporter superfamily DFR86_07695 49857f43a74d1ac37d19c5631c338b21 178 Gene3D G3DSA:1.20.1540.10 1 175 6.1E-18 T 31-10-2018 IPR035952 Rhomboid-like superfamily DFR86_07695 49857f43a74d1ac37d19c5631c338b21 178 SUPERFAMILY SSF144091 7 171 2.88E-24 T 31-10-2018 DFR86_07695 49857f43a74d1ac37d19c5631c338b21 178 Pfam PF01694 Rhomboid family 34 168 3.7E-17 T 31-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 DFR86_04520 b7ddb6bf0a429b22091f9386f587f633 474 SUPERFAMILY SSF161098 260 455 1.96E-20 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_04520 b7ddb6bf0a429b22091f9386f587f633 474 Gene3D G3DSA:1.10.3720.10 250 470 4.6E-17 T 31-10-2018 IPR035906 MetI-like superfamily DFR86_04520 b7ddb6bf0a429b22091f9386f587f633 474 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 280 462 2.1E-20 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR86_02195 7b10ef30236fd9a204bf83df60c819aa 293 Gene3D G3DSA:3.20.20.105 29 221 7.1E-7 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR86_02195 7b10ef30236fd9a204bf83df60c819aa 293 SUPERFAMILY SSF51713 31 198 4.32E-18 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR86_08670 208d86481af4a19ebfe3d4e2c816205b 720 Pfam PF01496 V-type ATPase 116kDa subunit family 601 693 2.0E-9 T 31-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_08670 208d86481af4a19ebfe3d4e2c816205b 720 Pfam PF01496 V-type ATPase 116kDa subunit family 167 380 1.7E-23 T 31-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR86_09975 b17097f77aee4a3474b17352f02b259f 272 Pfam PF00892 EamA-like transporter family 136 268 1.3E-16 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR86_09975 b17097f77aee4a3474b17352f02b259f 272 Pfam PF00892 EamA-like transporter family 6 127 2.3E-7 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR86_09975 b17097f77aee4a3474b17352f02b259f 272 SUPERFAMILY SSF103481 175 271 4.58E-10 T 31-10-2018 DFR86_04185 bf240bcfa5c32199d2aa366c55c54789 518 Gene3D G3DSA:1.20.1740.10 34 513 9.4E-18 T 31-10-2018 DFR86_04185 bf240bcfa5c32199d2aa366c55c54789 518 Pfam PF00324 Amino acid permease 27 509 1.6E-86 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR86_04185 bf240bcfa5c32199d2aa366c55c54789 518 PIRSF PIRSF006060 1 516 3.1E-25 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_07935 e938f5c675e4d14110b6aa7d62fa42d1 409 Pfam PF01566 Natural resistance-associated macrophage protein 47 386 7.4E-44 T 31-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 DFR86_00270 f83ed2aabd7490006b8f28dfcf1371f4 204 Gene3D G3DSA:1.10.10.10 137 200 1.7E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_00270 f83ed2aabd7490006b8f28dfcf1371f4 204 Pfam PF04967 HTH DNA binding domain 145 197 8.3E-24 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR86_00270 f83ed2aabd7490006b8f28dfcf1371f4 204 SUPERFAMILY SSF88659 143 201 1.46E-7 T 31-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like DFR86_00675 9c76e621b30f8387f25463183a16d611 305 SUPERFAMILY SSF49899 48 302 7.92E-38 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily DFR86_00675 9c76e621b30f8387f25463183a16d611 305 Pfam PF01670 Glycosyl hydrolase family 12 62 303 6.0E-18 T 31-10-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 DFR86_00675 9c76e621b30f8387f25463183a16d611 305 Gene3D G3DSA:2.60.120.180 37 304 2.7E-53 T 31-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 DFR86_10330 a3580de6abedd442cf88779ebd463e84 268 Pfam PF03956 Lysine exporter LysO 80 265 1.7E-43 T 31-10-2018 IPR005642 Lysine exporter LysO DFR86_10330 a3580de6abedd442cf88779ebd463e84 268 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 98 251 7.0E-37 T 31-10-2018 IPR005642 Lysine exporter LysO DFR86_00445 064f31d43920fe81ff4766c46e64ee85 320 Pfam PF06157 Protein of unknown function (DUF973) 5 320 1.1E-71 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR86_02245 b1984a7e5f5c6f6c5aaeafc99848e976 215 SUPERFAMILY SSF56024 1 48 8.48E-5 T 31-10-2018 DFR86_02245 b1984a7e5f5c6f6c5aaeafc99848e976 215 Pfam PF03021 Influenza C virus M2 protein 95 166 2.0E-4 T 31-10-2018 IPR004267 Influenza C virus M2 protein DFR86_11655 e11e63ba7e27086aeafa597a62488fbe 362 TIGRFAM TIGR03157 cas_Csc2: CRISPR type I-D/CYANO-associated protein Csc2 36 314 3.2E-57 T 31-10-2018 IPR017574 CRISPR-associated protein Csc2 DFR86_10220 7805917602d7c01f20f0876c0c74ed8d 180 SUPERFAMILY SSF52833 83 176 1.8E-13 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR86_10220 7805917602d7c01f20f0876c0c74ed8d 180 Pfam PF13192 Thioredoxin domain 101 161 1.3E-9 T 31-10-2018 IPR012336 Thioredoxin-like fold DFR86_10220 7805917602d7c01f20f0876c0c74ed8d 180 Gene3D G3DSA:3.40.30.80 1 169 2.0E-51 T 31-10-2018 DFR86_11025 dd22c5d9c8b3cd0dbe314d0d32b9d5b7 271 Pfam PF06157 Protein of unknown function (DUF973) 7 269 1.1E-44 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR86_10720 4a893cff82297681f2187415fe6de472 52 Pfam PF04945 YHS domain 6 46 1.5E-7 T 31-10-2018 IPR007029 YHS domain DFR86_06715 7c47c4d9edaa9c051fe5d05786d4445e 157 SUPERFAMILY SSF52954 2 147 3.04E-19 T 31-10-2018 DFR86_06715 7c47c4d9edaa9c051fe5d05786d4445e 157 Gene3D G3DSA:3.40.50.10480 1 147 2.5E-21 T 31-10-2018 DFR86_08770 59599ff4d2a80a7f22c154ddd8f30bef 111 Pfam PF09943 Uncharacterized protein conserved in archaea (DUF2175) 6 105 1.0E-31 T 31-10-2018 IPR018686 Protein of unknown function DUF2175 DFR86_02800 bd7e8f9cdf60ac4a31245be11d68c34f 92 Pfam PF03477 ATP cone domain 3 70 2.1E-6 T 31-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 DFR86_01940 9ce0462de5e4414400d3f66111475561 161 Pfam PF10061 Uncharacterized conserved protein (DUF2299) 8 144 4.3E-44 T 31-10-2018 IPR018747 Protein of unknown function DUF2299 DFR86_01940 9ce0462de5e4414400d3f66111475561 161 Gene3D G3DSA:3.30.1460.10 4 149 1.4E-36 T 31-10-2018 DFR86_10765 b1aa269cfb9287b3eeaf0d6508878591 437 Pfam PF02754 Cysteine-rich domain 233 331 9.8E-6 T 31-10-2018 IPR004017 Cysteine-rich domain DFR86_02180 7c12fa028b5d938c2498a0877f838dec 1002 SUPERFAMILY SSF52540 42 220 4.72E-5 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_10555 a509934a9518343a1bce030905099222 209 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 21 194 2.0E-28 T 31-10-2018 DFR86_11425 b896ee2dc65ff924318cb44da3373a1e 197 Pfam PF03787 RAMP superfamily 41 180 1.6E-4 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_02050 27d81412d050b8e61becc5663b3bae70 347 SUPERFAMILY SSF52768 4 318 1.29E-97 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily DFR86_02050 27d81412d050b8e61becc5663b3bae70 347 Gene3D G3DSA:3.40.800.20 2 345 2.6E-100 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR86_02050 27d81412d050b8e61becc5663b3bae70 347 Pfam PF00850 Histone deacetylase domain 25 303 5.8E-77 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR86_02050 27d81412d050b8e61becc5663b3bae70 347 PRINTS PR01271 Histone deacetylase signature 200 213 4.3E-5 T 31-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 DFR86_02050 27d81412d050b8e61becc5663b3bae70 347 PRINTS PR01271 Histone deacetylase signature 57 75 4.3E-5 T 31-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 DFR86_02050 27d81412d050b8e61becc5663b3bae70 347 PRINTS PR01271 Histone deacetylase signature 217 235 4.3E-5 T 31-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 DFR86_02050 27d81412d050b8e61becc5663b3bae70 347 PRINTS PR01270 Histone deacetylase superfamily signature 153 168 4.0E-16 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR86_02050 27d81412d050b8e61becc5663b3bae70 347 PRINTS PR01270 Histone deacetylase superfamily signature 239 249 4.0E-16 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR86_02050 27d81412d050b8e61becc5663b3bae70 347 PRINTS PR01270 Histone deacetylase superfamily signature 122 145 4.0E-16 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR86_04960 62b5a83c86f388002f66ddab74a20ac7 484 Pfam PF00324 Amino acid permease 37 463 1.0E-6 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR86_04960 62b5a83c86f388002f66ddab74a20ac7 484 PIRSF PIRSF006060 1 483 3.4E-18 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR86_04960 62b5a83c86f388002f66ddab74a20ac7 484 Gene3D G3DSA:1.20.1740.10 11 481 7.2E-9 T 31-10-2018 DFR86_07390 72b7226c264d1a0e5ee46d36ee43559c 310 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 300 5.4E-76 T 31-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DFR86_07390 72b7226c264d1a0e5ee46d36ee43559c 310 Gene3D G3DSA:3.90.245.10 2 310 2.2E-108 T 31-10-2018 IPR036452 Ribonucleoside hydrolase-like DFR86_07390 72b7226c264d1a0e5ee46d36ee43559c 310 SUPERFAMILY SSF53590 4 307 5.49E-91 T 31-10-2018 IPR036452 Ribonucleoside hydrolase-like DFR86_02475 9fa1af698c3bb7d307979c208ed47792 330 SMART SM00933 50 302 2.5E-33 T 31-10-2018 IPR018977 NurA domain DFR86_02475 9fa1af698c3bb7d307979c208ed47792 330 Pfam PF09376 NurA domain 51 301 3.2E-22 T 31-10-2018 IPR018977 NurA domain DFR86_08010 9761e301d4e376ce382beb6254d5f1c9 394 Pfam PF13641 Glycosyltransferase like family 2 42 269 6.0E-37 T 31-10-2018 DFR86_08010 9761e301d4e376ce382beb6254d5f1c9 394 SUPERFAMILY SSF53448 41 312 7.22E-57 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_08010 9761e301d4e376ce382beb6254d5f1c9 394 Gene3D G3DSA:3.90.550.10 31 253 1.9E-47 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_11350 8ce3bdba72b6394406ff0e582647d28f 105 Pfam PF11494 Ta0938 1 104 6.9E-48 T 31-10-2018 IPR021585 Ta0938 DFR86_04095 7b9d4385cc7c1848d83e09c4fd6c3d1f 121 Pfam PF07843 Protein of unknown function (DUF1634) 7 114 8.4E-29 T 31-10-2018 IPR012861 Protein of unknown function DUF1634 DFR86_08830 911ac272a0aa3a45e44ed651173d4235 207 Gene3D G3DSA:3.20.20.70 8 204 1.0E-24 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR86_08830 911ac272a0aa3a45e44ed651173d4235 207 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 4 204 28.325 T 31-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DFR86_08830 911ac272a0aa3a45e44ed651173d4235 207 SUPERFAMILY SSF51569 2 204 1.72E-30 T 31-10-2018 DFR86_08830 911ac272a0aa3a45e44ed651173d4235 207 Pfam PF01487 Type I 3-dehydroquinase 16 200 5.9E-13 T 31-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DFR86_11410 a76126b839828889692508633bc4ff21 249 Pfam PF03787 RAMP superfamily 37 205 1.9E-10 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_10670 0e7b84a9b2888c453d9e2cc7552a0c1e 320 TIGRFAM TIGR03155 sulfolob_CbsB: cytochrome b558/566, subunit B 8 309 3.3E-63 T 31-10-2018 IPR017573 Cytochrome b558/566, subunit B DFR86_05390 1b153fac15320acf86c010db679a03c3 115 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 8 45 1.1E-13 T 31-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 DFR86_00690 dba31cfca755177b1faeefe785d1bfbf 470 SUPERFAMILY SSF52540 27 258 1.66E-9 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_00690 dba31cfca755177b1faeefe785d1bfbf 470 SMART SM00382 41 260 0.0087 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR86_08230 fc8161dfb7e1ec498ffe380a6f8f2879 257 Gene3D G3DSA:1.10.12.10 200 257 1.1E-17 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal DFR86_08230 fc8161dfb7e1ec498ffe380a6f8f2879 257 Gene3D G3DSA:3.90.226.10 2 198 7.9E-76 T 31-10-2018 DFR86_08230 fc8161dfb7e1ec498ffe380a6f8f2879 257 SUPERFAMILY SSF52096 2 256 1.22E-90 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR86_08230 fc8161dfb7e1ec498ffe380a6f8f2879 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 DFR86_08230 fc8161dfb7e1ec498ffe380a6f8f2879 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 256 8.0E-76 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR86_03775 aa62e6680418b2630c2649e7395b9cfe 278 SUPERFAMILY SSF56281 12 255 2.75E-27 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_03775 aa62e6680418b2630c2649e7395b9cfe 278 Gene3D G3DSA:3.60.15.10 1 276 7.2E-70 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR86_03775 aa62e6680418b2630c2649e7395b9cfe 278 Pfam PF00753 Metallo-beta-lactamase superfamily 30 83 1.3E-8 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR86_08250 3916940aabe98481bf449029696e5464 126 SUPERFAMILY SSF49478 60 108 7.45E-7 T 31-10-2018 DFR86_01270 9fe487ae2b60c7f9e1fdc6d53418ca6b 143 Gene3D G3DSA:1.20.1260.10 1 143 8.3E-50 T 31-10-2018 IPR012347 Ferritin-like DFR86_01270 9fe487ae2b60c7f9e1fdc6d53418ca6b 143 Pfam PF02915 Rubrerythrin 11 135 3.0E-27 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 DFR86_01270 9fe487ae2b60c7f9e1fdc6d53418ca6b 143 SUPERFAMILY SSF47240 4 141 2.94E-39 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR86_01685 5e10630f4c26e0eb10afbfa0ec032d63 127 Pfam PF01986 Domain of unknown function DUF123 26 108 1.6E-16 T 31-10-2018 IPR002837 Protein of unknown function DUF123 DFR86_09705 c55f0cda5c181d54642812effc36da8e 52 Pfam PF04758 Ribosomal protein S30 4 50 1.7E-12 T 31-10-2018 IPR006846 Ribosomal protein S30 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR86_07625 2e41b260c64a50edbaf15e7a1d94b0f5 131 SUPERFAMILY SSF46785 6 89 2.59E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_07625 2e41b260c64a50edbaf15e7a1d94b0f5 131 Gene3D G3DSA:1.10.10.10 6 118 4.9E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_06440 dea10131ac66e2d2c1c5f10624e2d3a3 58 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 3 55 14.016 T 31-10-2018 IPR023531 Preprotein translocase subunit SecG DFR86_06440 dea10131ac66e2d2c1c5f10624e2d3a3 58 Pfam PF03911 Sec61beta family 15 53 4.4E-15 T 31-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR86_03570 022b825d994ab18e216ec8290b56c1c9 230 Pfam PF01944 Stage II sporulation protein M 15 161 1.1E-9 T 31-10-2018 IPR002798 Stage II sporulation protein M-like DFR86_01785 d1d7b7df1923a8165283a51eb0a7eba4 382 Pfam PF05559 Protein of unknown function (DUF763) 5 338 1.7E-123 T 31-10-2018 IPR008482 Protein of unknown function DUF763 DFR86_06455 3fb30de185a60f1c0c5add221529dd5d 126 Pfam PF04434 SWIM zinc finger 40 89 4.5E-6 T 31-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 DFR86_01560 fb457f74bfaa337f5c183fa65d75d7af 226 Gene3D G3DSA:3.40.50.11330 94 224 2.6E-39 T 31-10-2018 DFR86_01560 fb457f74bfaa337f5c183fa65d75d7af 226 Gene3D G3DSA:3.40.50.1860 1 93 1.0E-42 T 31-10-2018 DFR86_11465 167ea71a206a145bb658ba3f1151eeba 152 Pfam PF13274 Protein of unknown function (DUF4065) 43 144 1.2E-6 T 31-10-2018 IPR025272 Domain of unknown function DUF4065 DFR86_00855 29656ac17f2c5b8d39c8b5bb456fb6cd 556 Gene3D G3DSA:3.40.50.300 198 480 2.0E-8 T 31-10-2018 DFR86_00855 29656ac17f2c5b8d39c8b5bb456fb6cd 556 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 330 460 1.1E-8 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR86_00855 29656ac17f2c5b8d39c8b5bb456fb6cd 556 SUPERFAMILY SSF52540 2 476 5.87E-7 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR86_07340 6d086e6f6260fdfddb10b9c523b25848 229 Pfam PF12916 Protein of unknown function (DUF3834) 1 202 5.7E-49 T 31-10-2018 IPR024533 Protein of unknown function DUF3834 DFR86_07340 6d086e6f6260fdfddb10b9c523b25848 229 Gene3D G3DSA:3.40.190.200 1 229 1.1E-67 T 31-10-2018 DFR86_04945 18c572e346ccda19e4802589b984fc33 533 Gene3D G3DSA:1.10.4160.10 24 522 5.7E-93 T 31-10-2018 IPR038271 Purine-cytosine permease superfamily DFR86_04945 18c572e346ccda19e4802589b984fc33 533 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 41 470 4.6E-63 T 31-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 DFR86_00295 bb3b49425f4aad1ed222d8e3c397eb5b 373 SUPERFAMILY SSF56747 37 168 5.01E-6 T 31-10-2018 DFR86_08450 3225c17f4e9f6351a2db6eb802726a54 201 Pfam PF01914 MarC family integral membrane protein 8 197 2.2E-29 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 DFR86_10550 7e3e9d007a9c6d67c676dd38948f15c0 313 Pfam PF00146 NADH dehydrogenase 11 307 1.5E-32 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_07370 71c6636287dc3da5a8c6d994842ad598 113 Gene3D G3DSA:1.10.10.10 1 113 2.3E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_07370 71c6636287dc3da5a8c6d994842ad598 113 SUPERFAMILY SSF46785 1 104 4.08E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_00305 857119692c57a02413c8650c9b924af7 208 SUPERFAMILY SSF46785 14 76 3.15E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR86_00620 235c0d8a7d640ce7cb50c0b8a9ed4621 287 Pfam PF06157 Protein of unknown function (DUF973) 11 270 1.0E-50 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR86_07995 77cdf3e00978f533f02ff1f07fb17144 175 Pfam PF01955 Adenosylcobinamide amidohydrolase 8 168 3.5E-19 T 31-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ DFR86_08680 2bbfcdfbe523fa011d60d213d8aeda6a 312 SUPERFAMILY SSF140914 7 224 9.15E-35 T 31-10-2018 DFR86_08680 2bbfcdfbe523fa011d60d213d8aeda6a 312 Hamap MF_00701 DNA primase large subunit PriL [priL]. 10 310 23.876 T 31-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 DFR86_11615 68f76095d25d059e56eeed98e1284b97 901 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 446 771 1.7E-25 T 31-10-2018 IPR013407 CRISPR-associated protein Cmr2 DFR86_11615 68f76095d25d059e56eeed98e1284b97 901 Pfam PF12469 CRISPR-associated protein 210 333 2.8E-25 T 31-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal DFR86_11730 5f3c2ec26dcbefbd5d3c399374bbdf5b 198 Pfam PF10107 Endonuclease related to archaeal Holliday junction resolvase 12 179 7.1E-55 T 31-10-2018 IPR019287 Holliday junction resolvase-related domain DFR86_01800 60cb3ef242087a694a70d6aac3f65110 320 Pfam PF01384 Phosphate transporter family 20 278 3.1E-24 T 31-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 DFR86_10585 db695bcc2705ef4d235a260f3edf7ebb 251 Pfam PF01925 Sulfite exporter TauE/SafE 7 244 7.5E-39 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 DFR86_00110 cb12c443d4cb95f1531756ea1ff7c038 1009 Pfam PF05317 Thermopsin 79 325 7.0E-70 T 31-10-2018 IPR007981 Peptidase A5, thermopsin DFR86_07870 3aee6847cbf65d36aa1177d9d2813a8a 444 Gene3D G3DSA:3.20.70.20 3 443 1.5E-132 T 31-10-2018 DFR86_07870 3aee6847cbf65d36aa1177d9d2813a8a 444 Pfam PF05167 Uncharacterised ACR (DUF711) 14 398 2.3E-122 T 31-10-2018 IPR007841 Uncharacterised protein family UPF0210 DFR86_07870 3aee6847cbf65d36aa1177d9d2813a8a 444 SUPERFAMILY SSF51998 4 437 8.06E-126 T 31-10-2018 DFR86_09175 5393256d8127accb5962bf5657dfd46e 72 SUPERFAMILY SSF64307 8 66 8.63E-11 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_09175 5393256d8127accb5962bf5657dfd46e 72 Pfam PF01206 Sulfurtransferase TusA 8 66 2.1E-9 T 31-10-2018 IPR001455 TusA-like domain DFR86_09175 5393256d8127accb5962bf5657dfd46e 72 Gene3D G3DSA:3.30.110.40 6 72 7.3E-9 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR86_00400 68d48a7e3589ea0b638ea9993ca6e25c 382 Gene3D G3DSA:3.40.91.30 211 365 1.7E-8 T 31-10-2018 IPR011578 T7 endonuclease I-like GO:0003677|GO:0004536 DFR86_00170 ab0ecab3f6b1e4f8bbbb052146eaedea 212 Pfam PF03787 RAMP superfamily 18 170 4.5E-11 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR86_00170 ab0ecab3f6b1e4f8bbbb052146eaedea 212 PIRSF PIRSF032748 8 212 1.6E-113 T 31-10-2018 IPR017005 Uncharacterised conserved protein UCP032748 DFR86_00340 a0281e31b3349ad7f0875ae0f1c6a646 187 SUPERFAMILY SSF56784 7 124 1.46E-5 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_00340 a0281e31b3349ad7f0875ae0f1c6a646 187 Gene3D G3DSA:3.40.50.1000 41 146 1.8E-6 T 31-10-2018 IPR023214 HAD superfamily DFR86_05340 b8b1ff33e726a2e0cf580e3ecb9bccb8 163 Pfam PF02926 THUMP domain 27 150 1.9E-8 T 31-10-2018 IPR004114 THUMP domain GO:0003723 DFR86_05340 b8b1ff33e726a2e0cf580e3ecb9bccb8 163 SUPERFAMILY SSF143437 81 150 6.63E-8 T 31-10-2018 DFR86_07590 911150a4eae228b1b4eca482219fef28 346 Pfam PF01523 Putative modulator of DNA gyrase 27 223 5.6E-21 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 DFR86_07590 911150a4eae228b1b4eca482219fef28 346 SUPERFAMILY SSF111283 146 340 3.14E-31 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 DFR86_07245 d5ce363d56a01191d83df709af458620 288 SUPERFAMILY SSF51905 3 160 4.75E-6 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR86_05610 8e66fce6ee097bf0ca241e50118f5c92 459 Gene3D G3DSA:3.90.550.10 38 257 2.4E-31 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_05610 8e66fce6ee097bf0ca241e50118f5c92 459 SUPERFAMILY SSF53448 44 312 8.84E-38 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR86_05610 8e66fce6ee097bf0ca241e50118f5c92 459 Pfam PF13632 Glycosyl transferase family group 2 134 347 9.8E-23 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR86_02965 ac9cd9ced885c336e261082156870593 195 Pfam PF07185 Protein of unknown function (DUF1404) 69 191 1.1E-6 T 31-10-2018 IPR009844 Protein of unknown function DUF1404 DFR86_06575 32fd30603abbef9394e4d3ace4cad474 154 Pfam PF09895 RecB-family nuclease (DUF2122) 38 145 4.9E-33 T 31-10-2018 IPR018665 Protein of unknown function DUF2122, RecB-family nuclease-related DFR86_10545 a2f28222e831df3f5fb5b3b62826aece 583 Pfam PF00361 Proton-conducting membrane transporter 94 319 7.1E-22 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_11570 f761369369f4da17867160b6fac9b5d8 345 TIGRFAM TIGR03876 cas_csaX: CRISPR type I-A/APERN-associated protein CsaX 31 315 1.9E-136 T 31-10-2018 IPR022297 CRISPR-associated protein, CsaX DFR86_11545 63d726c0a758da739700a0bba1ea1a86 140 Pfam PF09702 CRISPR-associated protein (Cas_Csa5) 23 127 2.1E-50 T 31-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 DFR86_11545 63d726c0a758da739700a0bba1ea1a86 140 TIGRFAM TIGR01878 cas_Csa5: CRISPR type I-A/APERN-associated protein Csa5 23 127 5.1E-41 T 31-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 DFR86_10375 cc24dd8db49debd3541479ab9e02c65e 226 SUPERFAMILY SSF48371 5 207 3.02E-5 T 31-10-2018 IPR016024 Armadillo-type fold DFR86_04855 5941cdca7385f2f95014952c84b0992e 88 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 29 4.6E-8 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR86_04855 5941cdca7385f2f95014952c84b0992e 88 SMART SM00661 2 49 2.5E-13 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR86_11185 0db0d72a393c09fca86d10dacc2b11fa 194 Pfam PF09335 SNARE associated Golgi protein 26 152 3.3E-15 T 31-10-2018 IPR032816 SNARE associated Golgi protein DFR86_10270 a0a169e8a6e724dd83b660673c12333c 409 Pfam PF04143 Sulphur transport 48 398 2.4E-22 T 31-10-2018 IPR007272 Sulphur transport domain DFR86_11495 800147b97350a077157b93ad48160301 71 SUPERFAMILY SSF160980 5 53 9.02E-5 T 31-10-2018 DFR86_04620 0a54a08f3e569024a872ca12d5b91958 95 Gene3D G3DSA:1.10.10.10 10 78 1.2E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR86_01580 8c5fa23713dc04634f9a707c84b4bdfa 201 Pfam PF03458 UPF0126 domain 7 79 6.2E-17 T 31-10-2018 IPR005115 Uncharacterised domain UPF0126 DFR86_01580 8c5fa23713dc04634f9a707c84b4bdfa 201 Pfam PF03458 UPF0126 domain 93 166 4.1E-22 T 31-10-2018 IPR005115 Uncharacterised domain UPF0126 DFR86_07295 e7d0d224c0737d02f8413a44319332a1 56 Gene3D G3DSA:2.20.28.160 1 56 6.3E-27 T 31-10-2018 DFR86_03750 ab43427b855e8fc39cd659a506fbe8b2 105 SUPERFAMILY SSF46689 45 97 6.81E-5 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 DFR86_02835 cc077ae0dc63947147ca7abe74c07f3c 245 Pfam PF01988 VIT family 20 233 1.4E-45 T 31-10-2018 IPR008217 Ccc1 family DFR86_04355 3563ddc2043a350dea5870161aa454b9 130 Gene3D G3DSA:3.30.70.790 48 130 4.3E-7 T 31-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 DFR86_03210 1dbac375802b03452c3092ff70ba6ba1 234 Pfam PF04981 NMD3 family 6 234 8.2E-46 T 31-10-2018 IPR007064 Nmd3, N-terminal DFR86_11500 0973a0c9a279f035a3ebb86c678799b6 41 Pfam PF09703 CRISPR-associated protein (Cas_Csa4) 4 40 6.6E-6 T 31-10-2018 IPR010184 CRISPR-associated protein, MJ0385 DFR86_06350 90079f9bc5d8e54a763d81f3c46c2ad5 310 Gene3D G3DSA:3.30.70.3460 55 162 4.2E-12 T 31-10-2018 DFR86_06350 90079f9bc5d8e54a763d81f3c46c2ad5 310 Gene3D G3DSA:3.30.70.3460 187 307 1.7E-14 T 31-10-2018 DFR86_08305 a809a8acdcdcb8b48feee48fe91c9927 46 SUPERFAMILY SSF47598 4 43 6.12E-9 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR86_08305 a809a8acdcdcb8b48feee48fe91c9927 46 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 43 4.1E-10 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR86_08730 b7010022bcea1652b518011f6e8a38fa 95 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 11 95 4.4E-11 T 31-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like DFR86_02280 c11d65009a1152b6f91ca2527833a93a 436 Pfam PF05317 Thermopsin 28 248 1.2E-23 T 31-10-2018 IPR007981 Peptidase A5, thermopsin DFR86_07475 d4356ffd5a63bac5e5a1d592403f56b0 292 PIRSF PIRSF018978 2 286 3.8E-43 T 31-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 DFR86_05025 8fee7473cfc51e5521d9aa23530e1247 169 Pfam PF06939 Protein of unknown function (DUF1286) 1 117 8.0E-37 T 31-10-2018 IPR009705 Sulfolobus virus STSV1, Orf8 DFR86_09380 8c0ae56660b528eb36edd02cc5b8edb5 117 Gene3D G3DSA:2.60.40.790 32 117 1.8E-5 T 31-10-2018 IPR008978 HSP20-like chaperone DFR86_09380 8c0ae56660b528eb36edd02cc5b8edb5 117 SUPERFAMILY SSF49764 40 117 3.53E-9 T 31-10-2018 IPR008978 HSP20-like chaperone DFR86_01455 46a8b6ce2e07a35bf4c1840c6df044ab 156 Pfam PF13240 zinc-ribbon domain 5 24 2.3E-6 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR86_00910 514b4407708087ec252d57739c83b452 466 Pfam PF01943 Polysaccharide biosynthesis protein 9 260 5.4E-10 T 31-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 DFR86_10795 e8c2aa74b532b4a07db3d02a313710e5 168 SUPERFAMILY SSF56784 16 164 5.75E-8 T 31-10-2018 IPR036412 HAD-like superfamily DFR86_11140 d86d9b5969649bd8dd27dab48aaad02a 113 Pfam PF02416 mttA/Hcf106 family 8 55 8.0E-8 T 31-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 DFR86_09920 7f78554994467253214db618703b1c29 91 Gene3D G3DSA:1.20.120.970 1 91 9.9E-36 T 31-10-2018 DFR86_08720 09f8e57ae1090d706afa52d0271ea06b 457 Pfam PF00361 Proton-conducting membrane transporter 118 407 3.6E-40 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR86_11605 c32ff85f38bdf66f804dac56c230e7b8 524 TIGRFAM TIGR01894 cas_TM1795_cmr1: CRISPR type III-B/RAMP module RAMP protein Cmr1 24 206 9.2E-13 T 31-10-2018 IPR007522 CRISPR-associated protein TM1795 DFR86_09035 4874d593f56c4340130121d9869f7934 203 SUPERFAMILY SSF56112 39 167 5.2E-11 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR86_02395 3869e3d6aa70db3561620943d5b23921 58 Pfam PF07282 Putative transposase DNA-binding domain 2 55 8.0E-20 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR86_10940 8a86f90940b5b6f6547c20bd26524415 425 SUPERFAMILY SSF88723 226 344 1.39E-5 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR86_00175 e4a5f8e04747ac3a7d4a0449fd853613 292 Pfam PF03787 RAMP superfamily 14 185 1.4E-5 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein