locus-tag	class	description
BI364_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BI364_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BI364_00020	COG0187	DNA topoisomerase II activity
BI364_00025	COG0339	signal peptide processing
BI364_00035	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BI364_00040	COG0697	spore germination
BI364_00050	COG0543	2 iron, 2 sulfur cluster binding
BI364_00050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BI364_00065	COG1587	Uroporphyrinogen-III synthase
BI364_00070	COG0181	hydroxymethylbilane synthase activity
BI364_00085	COG3275	phosphorelay sensor kinase activity
BI364_00090	COG0165	Argininosuccinate lyase
BI364_00120	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BI364_00155	COG0019	diaminopimelate decarboxylase activity
BI364_00160	COG4106	trans-aconitate 2-methyltransferase activity
BI364_00165	COG0425	Belongs to the sulfur carrier protein TusA family
BI364_00170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BI364_00180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BI364_00185	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BI364_00190	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BI364_00210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BI364_00220	COG0508	dehydrogenase complex catalyzes the overall conversion of
BI364_00230	COG0425	Belongs to the sulfur carrier protein TusA family
BI364_00235	COG1309	transcriptional regulator
BI364_00245	COG0281	malic enzyme
BI364_00250	COG1525	nuclease
BI364_00255	COG0254	rRNA binding
BI364_00260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BI364_00280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BI364_00285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BI364_00290	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BI364_00295	COG1561	YicC-like family, N-terminal region
BI364_00305	COG0071	Belongs to the small heat shock protein (HSP20) family
BI364_00315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BI364_00325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BI364_00330	COG0315	cyclic pyranopterin monophosphate synthase activity
BI364_00355	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BI364_00400	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BI364_00415	COG1510	regulation of RNA biosynthetic process
BI364_00435	COG1538	Outer membrane efflux protein
BI364_00440	COG1566	PFAM secretion protein HlyD family protein
BI364_00445	COG2814	Major facilitator Superfamily
BI364_00455	COG0194	GDP metabolic process
BI364_00460	COG1758	RNA polymerase activity
BI364_00465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BI364_00475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BI364_00480	COG3258	Cytochrome c
BI364_00490	COG1515	deoxyribonuclease V activity
BI364_00520	COG5001	Diguanylate cyclase
BI364_00520	COG5002	protein histidine kinase activity
BI364_00535	COG3264	Mechanosensitive ion channel
BI364_00535	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BI364_00540	COG2223	nitrite transmembrane transporter activity
BI364_00545	COG0784	Response regulator, receiver
BI364_00545	COG3437	response regulator, receiver
BI364_00550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BI364_00550	COG4191	Histidine kinase
BI364_00555	COG0708	Exodeoxyribonuclease III
BI364_00565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BI364_00575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BI364_00590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BI364_00600	COG2003	Belongs to the UPF0758 family
BI364_00605	COG0156	8-amino-7-oxononanoate synthase activity
BI364_00610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BI364_00635	COG2885	chlorophyll binding
BI364_00640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BI364_00650	COG0408	coproporphyrinogen oxidase activity
BI364_00655	COG0009	L-threonylcarbamoyladenylate synthase
BI364_00665	COG2922	Belongs to the Smg family
BI364_00670	COG0758	DNA mediated transformation
BI364_00680	COG0242	peptide deformylase activity
BI364_00690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BI364_00700	COG5000	phosphorelay sensor kinase activity
BI364_00705	COG2204	response regulator
BI364_00710	COG0569	domain protein
BI364_00745	COG0037	tRNA processing
BI364_00755	COG1490	D-aminoacyl-tRNA deacylase activity
BI364_00760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BI364_00765	COG0131	Imidazoleglycerol-phosphate dehydratase
BI364_00770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BI364_00775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BI364_00780	COG0107	imidazoleglycerol-phosphate synthase activity
BI364_00785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BI364_00790	COG0140	phosphoribosyl-ATP diphosphatase activity
BI364_00800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BI364_00805	COG0805	protein transport
BI364_00825	COG3383	formate dehydrogenase (NAD+) activity
BI364_00835	COG4191	Histidine kinase
BI364_00845	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BI364_00860	COG0747	negative chemotaxis
BI364_00865	COG0601	transmembrane transport
BI364_00870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BI364_00875	COG0444	Belongs to the ABC transporter superfamily
BI364_00880	COG4608	Belongs to the ABC transporter superfamily
BI364_00885	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BI364_00905	COG0358	DNA primase activity
BI364_00910	COG0069	glutamate synthase activity
BI364_00910	COG0070	glutamate synthase
BI364_00910	COG0067	glutamate synthase
BI364_00920	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BI364_00925	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BI364_00930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BI364_00970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BI364_00980	COG0493	'glutamate synthase
BI364_00990	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BI364_01000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BI364_01010	COG2226	methyltransferase
BI364_01015	COG3278	Belongs to the heme-copper respiratory oxidase family
BI364_01030	COG2010	Cytochrome c
BI364_01060	COG2177	Part of the ABC transporter FtsEX involved in
BI364_01065	COG2884	Cell division ATP-binding protein ftsE
BI364_01070	COG0552	protein localization to endoplasmic reticulum
BI364_01075	COG0742	ribosomal rna small subunit methyltransferase
BI364_01080	COG1322	Protein conserved in bacteria
BI364_01085	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BI364_01095	COG2814	Major facilitator Superfamily
BI364_01130	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BI364_01215	COG2345	Transcriptional regulator
BI364_01240	COG3012	SEC-C Motif Domain Protein
BI364_01260	COG0517	IMP dehydrogenase activity
BI364_01260	COG4175	Glycine betaine
BI364_01270	COG0494	nUDIX hydrolase
BI364_01285	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BI364_01325	COG0038	chloride channel
BI364_01330	COG1872	DUF167
BI364_01365	COG0543	2 iron, 2 sulfur cluster binding
BI364_01370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BI364_01375	COG0540	Belongs to the ATCase OTCase family
BI364_01380	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BI364_01385	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BI364_01390	COG1678	Uncharacterized ACR, COG1678
BI364_01400	COG0189	ligase activity
BI364_01420	COG0840	transmembrane signaling receptor activity
BI364_01425	COG0643	Histidine kinase
BI364_01425	COG2198	Histidine kinase
BI364_01425	COG0784	Response regulator, receiver
BI364_01435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BI364_01440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BI364_01445	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BI364_01450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BI364_01455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BI364_01460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BI364_01470	COG0469	pyruvate kinase activity
BI364_01480	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BI364_01485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BI364_01490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BI364_01495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BI364_01535	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BI364_01540	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BI364_01545	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BI364_01560	COG1192	Involved in chromosome partitioning
BI364_01580	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BI364_01595	COG3002	Belongs to the UPF0753 family
BI364_01605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BI364_01630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BI364_01635	COG0546	phosphoglycolate phosphatase activity
BI364_01650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BI364_01655	COG0134	indole-3-glycerol-phosphate synthase activity
BI364_01660	COG1765	OsmC-like protein
BI364_01670	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BI364_01675	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BI364_01695	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BI364_01700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BI364_01715	COG0247	lactate metabolic process
BI364_01720	COG0456	acetyltransferase
BI364_01725	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BI364_01750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BI364_01780	COG0006	proline dipeptidase activity
BI364_01785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI364_01790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BI364_01795	COG1047	Peptidyl-prolyl cis-trans
BI364_01835	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BI364_01845	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BI364_01850	COG1792	Involved in formation and maintenance of cell shape
BI364_01855	COG1077	Cell shape determining protein MreB Mrl
BI364_01860	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BI364_01870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BI364_01875	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BI364_01880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BI364_01885	COG2890	protein-(glutamine-N5) methyltransferase activity
BI364_01890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BI364_01895	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BI364_01905	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BI364_01910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BI364_01920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BI364_01925	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BI364_01935	COG0012	GTP binding
BI364_01940	COG5001	Diguanylate cyclase
BI364_01940	COG3300	MHYT domain
BI364_01955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BI364_01955	COG2169	Transcriptional regulator
BI364_01990	COG1444	tRNA N-acetyltransferase activity
BI364_01995	COG1802	Transcriptional regulator
BI364_02025	COG0402	S-adenosylhomocysteine deaminase activity
BI364_02035	COG4319	ketosteroid isomerase
BI364_02065	COG1252	NADH dehydrogenase
BI364_02075	COG0616	signal peptide processing
BI364_02100	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BI364_02165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BI364_02175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BI364_02180	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BI364_02190	COG2201	protein-glutamate methylesterase activity
BI364_02200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BI364_02215	COG0252	asparaginase activity
BI364_02220	COG0811	peptide transport
BI364_02225	COG0848	biopolymer transport protein
BI364_02245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI364_02320	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BI364_02345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BI364_02375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BI364_02380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BI364_02390	COG1234	tRNA 3'-trailer cleavage
BI364_02410	COG1968	undecaprenyl-diphosphatase activity
BI364_02415	COG3706	GGDEF domain
BI364_02420	COG0617	tRNA 3'-terminal CCA addition
BI364_02435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BI364_02440	COG0243	molybdopterin cofactor binding
BI364_02445	COG0437	4 iron, 4 sulfur cluster binding
BI364_02450	COG3302	dmso reductase anchor subunit
BI364_02475	COG0058	SHG alpha-glucan phosphorylase activity
BI364_02480	COG0151	Belongs to the GarS family
BI364_02505	COG2199	diguanylate cyclase activity
BI364_02515	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BI364_02530	COG2264	protein methyltransferase activity
BI364_02535	COG0439	Biotin carboxylase
BI364_02540	COG0511	ligase activity, forming carbon-carbon bonds
BI364_02545	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BI364_02550	COG4232	protein-disulfide reductase activity
BI364_02580	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BI364_02585	COG0459	protein refolding
BI364_02595	COG0515	serine threonine protein kinase
BI364_02595	COG2815	serine threonine protein kinase
BI364_02630	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BI364_02645	COG0859	PFAM glycosyl transferase family 9
BI364_02650	COG0859	PFAM glycosyl transferase family 9
BI364_02660	COG0859	PFAM glycosyl transferase family 9
BI364_02665	COG0438	transferase activity, transferring glycosyl groups
BI364_02675	COG0859	PFAM glycosyl transferase family 9
BI364_02685	COG0438	transferase activity, transferring glycosyl groups
BI364_02690	COG0859	PFAM glycosyl transferase family 9
BI364_02695	COG1560	Kdo2-lipid A biosynthetic process
BI364_02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BI364_02710	COG1519	Transferase
BI364_02715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BI364_02730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BI364_02740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BI364_02745	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BI364_02780	COG0531	amino acid
BI364_02805	COG0667	Aldo Keto reductase
BI364_02815	COG4191	Histidine kinase
BI364_02870	COG2766	serine protein kinase
BI364_02875	COG2718	Belongs to the UPF0229 family
BI364_02880	COG2719	SpoVR family
BI364_02895	COG0789	Transcriptional regulator
BI364_02910	COG1522	sequence-specific DNA binding
BI364_02915	COG3608	succinylglutamate desuccinylase aspartoacylase
BI364_02920	COG1012	belongs to the aldehyde dehydrogenase family
BI364_02925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BI364_02930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BI364_02935	COG2423	ornithine cyclodeaminase activity
BI364_02940	COG0006	proline dipeptidase activity
BI364_02950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BI364_03020	COG3791	Glutathione-dependent formaldehyde-activating
BI364_03025	COG2207	Transcriptional regulator
BI364_03065	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BI364_03070	COG1970	mechanosensitive ion channel activity
BI364_03095	COG2814	Major facilitator Superfamily
BI364_03100	COG1280	lysine exporter protein (LysE YggA)
BI364_03105	COG1012	belongs to the aldehyde dehydrogenase family
BI364_03115	COG0069	glutamate synthase activity
BI364_03130	COG1902	pentaerythritol trinitrate reductase activity
BI364_03135	COG0640	Transcriptional regulator
BI364_03150	COG2081	HI0933 family
BI364_03155	COG0513	Belongs to the DEAD box helicase family
BI364_03160	COG1278	Cold shock
BI364_03170	COG0514	ATP-dependent DNA helicase (RecQ)
BI364_03225	COG0513	Belongs to the DEAD box helicase family
BI364_03240	COG2308	Evidence 4 Homologs of previously reported genes of
BI364_03260	COG3706	GGDEF domain
BI364_03265	COG2815	serine threonine protein kinase
BI364_03265	COG0515	serine threonine protein kinase
BI364_03270	COG0793	Belongs to the peptidase S41A family
BI364_03270	COG3409	Peptidoglycan-binding domain 1 protein
BI364_03275	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BI364_03280	COG0509	glycine decarboxylation via glycine cleavage system
BI364_03285	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BI364_03295	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BI364_03300	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BI364_03325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BI364_03350	COG0671	phosphoesterase, PA-phosphatase related
BI364_03385	COG1331	Highly conserved protein containing a thioredoxin domain
BI364_03405	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BI364_03425	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BI364_03465	COG3023	N-Acetylmuramoyl-L-alanine amidase
BI364_03480	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BI364_03490	COG3300	MHYT domain
BI364_03490	COG5001	Diguanylate cyclase
BI364_03495	COG0577	efflux transmembrane transporter activity
BI364_03495	COG1136	(ABC) transporter
BI364_03500	COG1136	(ABC) transporter
BI364_03500	COG0577	efflux transmembrane transporter activity
BI364_03505	COG0577	efflux transmembrane transporter activity
BI364_03505	COG1136	(ABC) transporter
BI364_03510	COG1566	PFAM secretion protein HlyD family protein
BI364_03520	COG0483	inositol monophosphate 1-phosphatase activity
BI364_03525	COG0406	alpha-ribazole phosphatase activity
BI364_03540	COG1410	methionine synthase
BI364_03540	COG0646	methionine synthase
BI364_03545	COG0519	Catalyzes the synthesis of GMP from XMP
BI364_03555	COG0500	methyltransferase
BI364_03625	COG0586	Pfam SNARE associated Golgi protein
BI364_03630	COG1230	cation diffusion facilitator family transporter
BI364_03645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BI364_03660	COG0316	Belongs to the HesB IscA family
BI364_03675	COG0739	heme binding
BI364_03680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BI364_03710	COG1196	nuclear chromosome segregation
BI364_03710	COG0741	lytic transglycosylase activity
BI364_03710	COG0739	heme binding
BI364_03735	COG3118	belongs to the thioredoxin family
BI364_03775	COG0121	glutamine amidotransferase
BI364_03780	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BI364_03820	COG0585	pseudouridine synthase activity
BI364_03825	COG0737	Belongs to the 5'-nucleotidase family
BI364_03845	COG0725	ABC transporter, periplasmic molybdate-binding protein
BI364_03855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BI364_03860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BI364_03870	COG0367	asparagine synthase
BI364_03875	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BI364_03895	COG0508	dehydrogenase complex catalyzes the overall conversion of
BI364_03900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BI364_03920	COG0137	argininosuccinate synthase activity
BI364_03925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BI364_03940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BI364_03955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BI364_03980	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BI364_03985	COG2894	cell division
BI364_04000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BI364_04000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BI364_04015	COG0189	ligase activity
BI364_04050	COG1473	amidohydrolase
BI364_04055	COG0730	response to heat
BI364_04060	COG0433	COG0433 Predicted ATPase
BI364_04065	COG3706	GGDEF domain
BI364_04080	COG0504	CTP synthase activity
BI364_04095	COG0789	Transcriptional regulator
BI364_04100	COG1278	Cold shock
BI364_04130	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BI364_04135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BI364_04140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BI364_04145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BI364_04145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BI364_04170	COG0303	'Molybdopterin
BI364_04175	COG0746	molybdenum cofactor guanylyltransferase activity
BI364_04185	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BI364_04190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BI364_04200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BI364_04205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BI364_04260	COG0557	exoribonuclease II activity
BI364_04265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BI364_04275	COG0360	Binds together with S18 to 16S ribosomal RNA
BI364_04280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BI364_04290	COG0359	binds to the 23S rRNA
BI364_04295	COG0305	Participates in initiation and elongation during chromosome replication
BI364_04300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BI364_04350	COG0123	including yeast histone deacetylase and acetoin utilization protein
BI364_04360	COG1193	negative regulation of DNA recombination
BI364_04370	COG0688	phosphatidylethanolamine metabolic process
BI364_04395	COG0076	glutamate decarboxylase activity
BI364_04400	COG0531	amino acid
BI364_04410	COG0129	dihydroxy-acid dehydratase activity
BI364_04415	COG3384	dioxygenase
BI364_04425	COG0488	(ABC) transporter
BI364_04430	COG0513	Belongs to the DEAD box helicase family
BI364_04435	COG4221	oxidoreductase activity
BI364_04500	COG2204	response regulator
BI364_04515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BI364_04520	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BI364_04530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BI364_04535	COG0166	Belongs to the GPI family
BI364_04540	COG0069	glutamate synthase activity
BI364_04550	COG0784	Response regulator, receiver
BI364_04550	COG2205	protein histidine kinase activity
BI364_04550	COG2198	Histidine kinase
BI364_04570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BI364_04575	COG4548	von Willebrand factor, type A
BI364_04595	COG0811	peptide transport
BI364_04620	COG3039	Transposase
BI364_04630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BI364_04630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BI364_04635	COG0802	atpase or kinase
BI364_04640	COG0860	N-Acetylmuramoyl-L-alanine amidase
BI364_04650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BI364_04655	COG1923	regulation of RNA biosynthetic process
BI364_04660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BI364_04665	COG0330	HflC and HflK could
BI364_04670	COG0330	HflC and HflK could
BI364_04680	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BI364_04685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BI364_04705	COG1196	nuclear chromosome segregation
BI364_04725	COG0298	carbon dioxide binding
BI364_04730	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BI364_04735	COG2204	response regulator
BI364_04745	COG0375	protein maturation
BI364_04775	COG0298	carbon dioxide binding
BI364_04790	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BI364_04855	COG0531	amino acid
BI364_04860	COG2095	MarC family integral membrane protein
BI364_04870	COG0686	Belongs to the AlaDH PNT family
BI364_04875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BI364_04880	COG1396	sequence-specific DNA binding
BI364_04880	COG1917	Cupin 2, conserved barrel domain protein
BI364_04885	COG1012	belongs to the aldehyde dehydrogenase family
BI364_04895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BI364_04900	COG0174	glutamine synthetase
BI364_04905	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BI364_04910	COG0174	glutamine synthetase
BI364_04920	COG3842	ATPase activity
BI364_04925	COG1176	ABC-type spermidine putrescine transport system, permease component I
BI364_04955	COG1850	ribulose-bisphosphate carboxylase activity
BI364_04970	COG0583	DNA-binding transcription factor activity
BI364_04975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BI364_04980	COG3002	Belongs to the UPF0753 family
BI364_05000	COG0418	dihydroorotase activity
BI364_05015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BI364_05020	COG2181	nitrate reductase activity
BI364_05025	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BI364_05030	COG1140	nitrate reductase beta subunit
BI364_05035	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BI364_05080	COG0826	peptidase U32
BI364_05085	COG0826	peptidase U32
BI364_05095	COG3154	lipid carrier protein
BI364_05100	COG1272	protein, Hemolysin III
BI364_05130	COG0175	sulfate reduction
BI364_05135	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BI364_05140	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BI364_05145	COG0450	alkyl hydroperoxide reductase
BI364_05150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BI364_05150	COG1648	precorrin-2 dehydrogenase activity
BI364_05155	COG2046	Belongs to the sulfate adenylyltransferase family
BI364_05175	COG2244	polysaccharide biosynthetic process
BI364_05185	COG2046	Belongs to the sulfate adenylyltransferase family
BI364_05185	COG0529	Catalyzes the synthesis of activated sulfate
BI364_05210	COG0386	Belongs to the glutathione peroxidase family
BI364_05225	COG0671	phosphoesterase, PA-phosphatase related
BI364_05235	COG1215	transferase activity, transferring glycosyl groups
BI364_05245	COG3707	response regulator
BI364_05250	COG2223	nitrite transmembrane transporter activity
BI364_05255	COG1116	anion transmembrane transporter activity
BI364_05255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BI364_05260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BI364_05265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BI364_05265	COG2146	nitrite reductase [NAD(P)H] activity
BI364_05275	COG1648	precorrin-2 dehydrogenase activity
BI364_05275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BI364_05280	COG1648	precorrin-2 dehydrogenase activity
BI364_05280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BI364_05300	COG2346	COG2346, Truncated hemoglobins
BI364_05310	COG1959	2 iron, 2 sulfur cluster binding
BI364_05330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BI364_05340	COG4178	(ABC) transporter
BI364_05345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BI364_05350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BI364_05370	COG1127	ABC transporter
BI364_05375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BI364_05385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BI364_05390	COG0066	3-isopropylmalate dehydratase activity
BI364_05410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BI364_05420	COG0101	tRNA pseudouridine synthase activity
BI364_05425	COG0135	phosphoribosylanthranilate isomerase activity
BI364_05430	COG0133	tryptophan synthase activity
BI364_05435	COG0159	tryptophan synthase activity
BI364_05440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BI364_05445	COG0285	dihydrofolate synthase activity
BI364_05455	COG1286	toxin biosynthetic process
BI364_05470	COG3300	MHYT domain
BI364_05470	COG5001	Diguanylate cyclase
BI364_05485	COG2379	hydroxypyruvate reductase
BI364_05500	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI364_05505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BI364_05510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BI364_05520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BI364_05550	COG0544	peptidyl-prolyl cis-trans isomerase activity
BI364_05555	COG0740	serine-type endopeptidase activity
BI364_05560	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BI364_05565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BI364_05585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BI364_05595	COG2204	response regulator
BI364_05610	COG0631	protein serine/threonine phosphatase activity
BI364_05620	COG1388	LysM domain
BI364_05620	COG0741	lytic transglycosylase activity
BI364_05630	COG0328	RNA-DNA hybrid ribonuclease activity
BI364_05635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BI364_05640	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BI364_05645	COG0733	neurotransmitter:sodium symporter activity
BI364_05655	COG2914	Belongs to the UPF0125 (RnfH) family
BI364_05660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI364_05665	COG0735	belongs to the Fur family
BI364_05675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BI364_05685	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BI364_05690	COG0443	Heat shock 70 kDa protein
BI364_05695	COG0484	heat shock protein binding
BI364_05700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BI364_05705	COG0505	Belongs to the CarA family
BI364_05710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BI364_05715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BI364_05720	COG1534	Rna-binding protein
BI364_05725	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BI364_05735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BI364_05740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BI364_05745	COG0149	triose-phosphate isomerase activity
BI364_05760	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BI364_05765	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BI364_05770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BI364_05775	COG0649	NAD binding
BI364_05785	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BI364_05795	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BI364_05800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BI364_05810	COG0713	ATP synthesis coupled electron transport
BI364_05840	COG0779	Required for maturation of 30S ribosomal subunits
BI364_05845	COG0195	Participates in both transcription termination and antitermination
BI364_05850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BI364_05855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BI364_05860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BI364_05870	COG0418	dihydroorotase activity
BI364_05875	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BI364_05890	COG0179	Fumarylacetoacetate (FAA) hydrolase
BI364_05900	COG4221	oxidoreductase activity
BI364_05905	COG1335	isochorismatase
BI364_05910	COG2329	Antibiotic biosynthesis monooxygenase
BI364_05915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BI364_05935	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BI364_05940	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BI364_05955	COG1162	GTPase activity
BI364_05960	COG2154	pterin-4-alpha-carbinolamine dehydratase
BI364_05965	COG0501	Belongs to the peptidase M48B family
BI364_05970	COG1476	TRANSCRIPTIONal
BI364_06020	COG0481	GTPase activity
BI364_06040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BI364_06045	COG1381	Involved in DNA repair and RecF pathway recombination
BI364_06050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BI364_06055	COG0736	holo-[acyl-carrier-protein] synthase activity
BI364_06070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BI364_06075	COG1247	-acetyltransferase
BI364_06090	COG0303	'Molybdopterin
BI364_06095	COG1763	Mo-molybdopterin cofactor biosynthetic process
BI364_06105	COG0330	HflC and HflK could
BI364_06115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BI364_06120	COG2207	Transcriptional regulator
BI364_06125	COG1064	alcohol dehydrogenase
BI364_06140	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BI364_06150	COG2207	Transcriptional regulator
BI364_06155	COG2814	Major facilitator Superfamily
BI364_06160	COG3118	belongs to the thioredoxin family
BI364_06165	COG2833	Protein of unknown function (DUF455)
BI364_06185	COG0501	Belongs to the peptidase M48B family
BI364_06190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BI364_06195	COG0183	Belongs to the thiolase family
BI364_06200	COG1028	Short-chain dehydrogenase reductase Sdr
BI364_06205	COG2200	EAL domain
BI364_06220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BI364_06230	COG0688	phosphatidylethanolamine metabolic process
BI364_06240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BI364_06245	COG2350	Protein conserved in bacteria
BI364_06250	COG2917	probably involved in intracellular septation
BI364_06255	COG0009	L-threonylcarbamoyladenylate synthase
BI364_06260	COG1994	Peptidase M50
BI364_06265	COG0180	Tryptophanyl-tRNA synthetase
BI364_06275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BI364_06285	COG0521	Mo-molybdopterin cofactor biosynthetic process
BI364_06310	COG1028	Short-chain dehydrogenase reductase Sdr
BI364_06315	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BI364_06320	COG1562	ergosterol biosynthetic process
BI364_06325	COG1562	ergosterol biosynthetic process
BI364_06335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BI364_06345	COG0402	S-adenosylhomocysteine deaminase activity
BI364_06350	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BI364_06360	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BI364_06370	COG0287	Prephenate dehydrogenase
BI364_06380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BI364_06390	COG0776	regulation of translation
BI364_06400	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BI364_06405	COG0284	orotidine-5'-phosphate decarboxylase activity
BI364_06410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BI364_06490	COG2391	methyltransferase activity
BI364_06505	COG4191	Histidine kinase
BI364_06515	COG0659	secondary active sulfate transmembrane transporter activity
BI364_06520	COG0791	NLP P60 protein
BI364_06530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BI364_06540	COG1199	ATP-dependent helicase activity
BI364_06570	COG0842	Transport permease protein
BI364_06575	COG0842	Transport permease protein
BI364_06580	COG1131	(ABC) transporter
BI364_06600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BI364_06630	COG1309	transcriptional regulator
BI364_06635	COG0058	SHG alpha-glucan phosphorylase activity
BI364_06640	COG1105	Belongs to the carbohydrate kinase PfkB family
BI364_06650	COG0469	pyruvate kinase activity
BI364_06655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BI364_06655	COG2146	nitrite reductase [NAD(P)H] activity
BI364_06670	COG0589	response to stress
BI364_06695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BI364_06725	COG1132	(ABC) transporter
BI364_06730	COG0438	transferase activity, transferring glycosyl groups
BI364_06735	COG0438	transferase activity, transferring glycosyl groups
BI364_06745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BI364_06755	COG1193	negative regulation of DNA recombination
BI364_06760	COG0670	Belongs to the BI1 family
BI364_06770	COG0640	Transcriptional regulator
BI364_06805	COG3039	Transposase
BI364_06865	COG0675	Transposase, IS605 OrfB family
BI364_06895	COG0675	Transposase, IS605 OrfB family
BI364_06955	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BI364_06965	COG0571	ribonuclease III activity
BI364_06985	COG3451	type IV secretory pathway VirB4
BI364_07040	COG1450	Type ii and iii secretion system protein
BI364_07055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BI364_07065	COG2165	general secretion pathway protein
BI364_07125	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BI364_07130	COG3657	addiction module killer protein
BI364_07190	COG5001	Diguanylate cyclase
BI364_07190	COG3300	MHYT domain
BI364_07195	COG0840	transmembrane signaling receptor activity
BI364_07200	COG2161	toxin-antitoxin pair type II binding
BI364_07205	COG4115	mRNA cleavage
BI364_07220	COG1484	DNA-dependent DNA replication
BI364_07225	COG4584	PFAM Integrase catalytic
BI364_07245	COG2890	protein-(glutamine-N5) methyltransferase activity
BI364_07305	COG0210	DNA helicase
BI364_07410	COG3039	Transposase
BI364_07420	COG3039	Transposase
BI364_07440	COG0730	response to heat
BI364_07445	COG0175	sulfate reduction
BI364_07455	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BI364_07460	COG0450	alkyl hydroperoxide reductase
BI364_07465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BI364_07465	COG1648	precorrin-2 dehydrogenase activity
BI364_07470	COG0175	sulfate reduction
BI364_07475	COG0529	Catalyzes the synthesis of activated sulfate
BI364_07475	COG2895	sulfate adenylyltransferase (ATP) activity
BI364_07535	COG4584	PFAM Integrase catalytic
BI364_07540	COG1484	DNA-dependent DNA replication
BI364_07580	COG0436	Aminotransferase
BI364_07595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BI364_07600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BI364_07605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BI364_07610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BI364_07615	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BI364_07620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BI364_07620	COG0072	phenylalanine-tRNA ligase activity
BI364_07625	COG0776	regulation of translation
BI364_07635	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BI364_07640	COG1185	polyribonucleotide nucleotidyltransferase activity
BI364_07645	COG0429	hydrolase of the alpha beta-hydrolase fold
BI364_07655	COG4454	pyrroloquinoline quinone binding
BI364_07660	COG0191	fructose-bisphosphate aldolase activity
BI364_07675	COG1414	Transcriptional regulator
BI364_07705	COG0625	glutathione transferase activity
BI364_07710	COG3550	peptidyl-serine autophosphorylation
BI364_07715	COG1396	sequence-specific DNA binding
BI364_07750	COG0047	phosphoribosylformylglycinamidine synthase activity
BI364_07750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BI364_07775	COG4181	ATPase activity
BI364_07785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BI364_07790	COG0596	Alpha beta hydrolase
BI364_07815	COG0745	RESPONSE REGULATOR receiver
BI364_07820	COG5002	protein histidine kinase activity
BI364_07850	COG0848	biopolymer transport protein
BI364_07855	COG0811	peptide transport
BI364_07865	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BI364_07880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BI364_07885	COG0586	Pfam SNARE associated Golgi protein
BI364_07890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BI364_07900	COG1201	RNA secondary structure unwinding
BI364_07975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BI364_07980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BI364_08000	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BI364_08005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BI364_08020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BI364_08035	COG3852	Histidine kinase
BI364_08045	COG1271	oxidase subunit
BI364_08050	COG0109	protoheme IX farnesyltransferase activity
BI364_08065	COG1845	cytochrome c oxidase, subunit III
BI364_08070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BI364_08100	COG2270	Major facilitator Superfamily
BI364_08105	COG2200	EAL domain
BI364_08110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BI364_08115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BI364_08125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BI364_08130	COG1570	exodeoxyribonuclease VII activity
BI364_08150	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BI364_08225	COG3220	belongs to the UPF0276 family
BI364_08285	COG1309	transcriptional regulator
BI364_08290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BI364_08295	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BI364_08330	COG2963	transposase activity
BI364_08345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BI364_08355	COG0477	Major facilitator Superfamily
BI364_08365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BI364_08410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BI364_08415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BI364_08435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BI364_08455	COG0546	phosphoglycolate phosphatase activity
BI364_08460	COG0424	maF-like protein
BI364_08465	COG5016	pyruvate
BI364_08465	COG0511	ligase activity, forming carbon-carbon bonds
BI364_08470	COG0439	Biotin carboxylase
BI364_08475	COG1399	metal-binding, possibly nucleic acid-binding protein
BI364_08480	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BI364_08485	COG0416	fatty acid biosynthetic process
BI364_08490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BI364_08500	COG1573	uracil-dna glycosylase
BI364_08505	COG0322	excinuclease ABC activity
BI364_08535	COG0668	transmembrane transport
BI364_08540	COG1752	Esterase of the alpha-beta hydrolase superfamily
BI364_08555	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BI364_08560	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BI364_08570	COG0492	ferredoxin-NADP+ reductase activity
BI364_08575	COG1674	ftsk spoiiie
BI364_08580	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BI364_08585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BI364_08600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BI364_08610	COG2957	Belongs to the agmatine deiminase family
BI364_08620	COG4591	ABC-type transport system involved in lipoprotein release permease component
BI364_08625	COG1136	(ABC) transporter
BI364_08635	COG0658	competence protein
BI364_08635	COG2333	competence protein COMEC
BI364_08640	COG1914	H( )-stimulated, divalent metal cation uptake system
BI364_08645	COG0811	peptide transport
BI364_08650	COG0848	biopolymer transport protein
BI364_08655	COG1132	(ABC) transporter
BI364_08665	COG1663	tetraacyldisaccharide 4'-kinase activity
BI364_08670	COG2835	tetraacyldisaccharide 4'-kinase activity
BI364_08675	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BI364_08710	COG0509	glycine decarboxylation via glycine cleavage system
BI364_08720	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BI364_08725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BI364_08735	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BI364_08740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BI364_08745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BI364_08780	COG2721	sulfolactate sulfo-lyase activity
BI364_08785	COG2188	Transcriptional regulator
BI364_08795	COG3220	belongs to the UPF0276 family
BI364_08825	COG0659	secondary active sulfate transmembrane transporter activity
BI364_08880	COG0302	gtp cyclohydrolase
BI364_08890	COG0494	nUDIX hydrolase
BI364_08900	COG1560	Kdo2-lipid A biosynthetic process
BI364_08910	COG5002	protein histidine kinase activity
BI364_08920	COG1396	sequence-specific DNA binding
BI364_08925	COG3135	benzoate transporter
BI364_08945	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BI364_09000	COG0166	Belongs to the GPI family
BI364_09005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BI364_09020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BI364_09025	COG3459	Glycosyltransferase 36 associated
BI364_09045	COG0723	plastoquinol--plastocyanin reductase activity
BI364_09055	COG1666	GTP binding
BI364_09060	COG2363	Small membrane protein
BI364_09065	COG1965	Belongs to the frataxin family
BI364_09075	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BI364_09080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BI364_09085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BI364_09090	COG1131	(ABC) transporter
BI364_09095	COG0842	Transport permease protein
BI364_09110	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BI364_09115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BI364_09120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BI364_09125	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BI364_09130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BI364_09135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BI364_09140	COG1028	Short-chain dehydrogenase reductase Sdr
BI364_09145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BI364_09150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BI364_09155	COG0542	response to heat
BI364_09160	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BI364_09175	COG0482	sulfurtransferase activity
BI364_09180	COG2915	High frequency lysogenization protein hflD homolog
BI364_09195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BI364_09230	COG0667	Aldo Keto reductase
BI364_09235	COG0598	Magnesium transport protein CorA
BI364_09240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BI364_09255	COG2850	peptidyl-arginine hydroxylation
BI364_09265	COG0714	Associated with various cellular activities
BI364_09300	COG0822	iron-sulfur transferase activity
BI364_09310	COG1959	2 iron, 2 sulfur cluster binding
BI364_09320	COG0033	Phosphoglucomutase
BI364_09330	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BI364_09335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BI364_09340	COG1053	succinate dehydrogenase
BI364_09360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BI364_09375	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BI364_09385	COG1278	Cold shock
BI364_09390	COG0724	RNA recognition motif
BI364_09395	COG2199	diguanylate cyclase activity
BI364_09405	COG4608	Belongs to the ABC transporter superfamily
BI364_09420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BI364_09425	COG0747	negative chemotaxis
BI364_09430	COG0582	viral genome integration into host DNA
BI364_09495	COG2963	transposase activity
BI364_09555	COG2963	transposase activity
BI364_09590	COG0436	Aminotransferase
BI364_09610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BI364_09615	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BI364_09625	COG1271	oxidase subunit
BI364_09630	COG1294	oxidase, subunit
BI364_09645	COG0109	protoheme IX farnesyltransferase activity
BI364_09690	COG1024	Enoyl-CoA hydratase
BI364_09715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BI364_09740	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BI364_09745	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BI364_09750	COG0148	phosphopyruvate hydratase activity
BI364_09755	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BI364_09760	COG0504	CTP synthase activity
BI364_09775	COG0825	malonyl-CoA metabolic process
BI364_09790	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BI364_09800	COG0583	DNA-binding transcription factor activity
BI364_09805	COG0477	Major facilitator Superfamily
BI364_09810	COG0436	Aminotransferase
BI364_09815	COG1160	GTP binding
BI364_09820	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BI364_09825	COG2976	Protein conserved in bacteria
BI364_09830	COG0124	histidyl-tRNA synthetase
BI364_09840	COG3063	Type IV pilus biogenesis stability protein PilW
BI364_09845	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BI364_09850	COG0105	UTP biosynthetic process
BI364_09860	COG0633	Ferredoxin
BI364_09865	COG0443	Heat shock 70 kDa protein
BI364_09880	COG0822	iron-sulfur transferase activity
BI364_09890	COG1959	2 iron, 2 sulfur cluster binding
BI364_09910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BI364_09915	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BI364_09920	COG1862	Preprotein translocase
BI364_09925	COG0343	queuine tRNA-ribosyltransferase activity
BI364_09930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BI364_10120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BI364_10150	COG0592	DNA-directed DNA polymerase activity
BI364_10255	COG2433	Pfam Transposase IS66
BI364_10260	COG3039	Transposase
BI364_10300	COG0166	Belongs to the GPI family
BI364_10320	COG0406	alpha-ribazole phosphatase activity
BI364_10380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BI364_10405	COG2003	Belongs to the UPF0758 family
BI364_10445	COG1028	Short-chain dehydrogenase reductase Sdr
BI364_10510	COG1335	isochorismatase
BI364_10525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BI364_10535	COG0444	Belongs to the ABC transporter superfamily
BI364_10540	COG0747	negative chemotaxis
BI364_10550	COG0723	plastoquinol--plastocyanin reductase activity
BI364_10560	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BI364_10565	COG2857	Cytochrome c1
BI364_10570	COG2153	protein acetylation
BI364_10590	COG1993	acr, cog1993
BI364_10595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BI364_10600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BI364_10610	COG0003	Pfam Anion-transporting ATPase
BI364_10620	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BI364_10625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BI364_10630	COG3115	cell septum assembly
BI364_10640	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BI364_10645	COG1070	Carbohydrate kinase
BI364_10650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BI364_10665	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI364_10675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BI364_10680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BI364_10700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BI364_10705	COG0575	Belongs to the CDS family
BI364_10710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BI364_10715	COG0233	cytoplasmic translational termination
BI364_10720	COG0528	UMP kinase activity
BI364_10725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BI364_10730	COG0052	Belongs to the universal ribosomal protein uS2 family
BI364_10735	COG0024	Methionine aminopeptidase
BI364_10740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BI364_10750	COG2171	N-acyltransferase activity
BI364_10760	COG1393	Belongs to the ArsC family
BI364_10765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BI364_10780	COG0795	lipopolysaccharide-transporting ATPase activity
BI364_10785	COG0795	lipopolysaccharide-transporting ATPase activity
BI364_10790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BI364_10805	COG0525	valine-tRNA ligase activity
BI364_10815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BI364_10820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BI364_10825	COG0581	inorganic phosphate transmembrane transporter activity
BI364_10840	COG3264	Mechanosensitive ion channel
BI364_10840	COG1196	nuclear chromosome segregation
BI364_10845	COG0189	ligase activity
BI364_10845	COG4067	protein conserved in archaea
BI364_10850	COG0189	ligase activity
BI364_10860	COG3431	PFAM Phosphate-starvation-inducible E
BI364_10865	COG0372	Belongs to the citrate synthase family
BI364_10875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BI364_10880	COG0456	acetyltransferase
BI364_10885	COG1573	uracil-dna glycosylase
BI364_10890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BI364_10895	COG0747	negative chemotaxis
BI364_10900	COG0601	transmembrane transport
BI364_10905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BI364_10915	COG1183	phosphatidylcholine synthase activity
BI364_10920	COG0688	phosphatidylethanolamine metabolic process
BI364_10925	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BI364_10935	COG0028	Belongs to the TPP enzyme family
BI364_10945	COG1794	racemase activity, acting on amino acids and derivatives
BI364_10970	COG1671	Belongs to the UPF0178 family
BI364_10985	COG0655	NAD(P)H dehydrogenase (quinone) activity
BI364_10990	COG0697	spore germination
BI364_11005	COG1028	Short-chain dehydrogenase reductase Sdr
BI364_11040	COG0488	(ABC) transporter
BI364_11055	COG3093	addiction module antidote protein HigA
BI364_11105	COG0577	efflux transmembrane transporter activity
BI364_11115	COG0432	Pfam Uncharacterised protein family UPF0047
BI364_11120	COG0438	transferase activity, transferring glycosyl groups
BI364_11130	COG0583	DNA-binding transcription factor activity
BI364_11135	COG0678	peroxiredoxin activity
BI364_11135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BI364_11180	COG0784	Response regulator, receiver
BI364_11180	COG0835	chemotaxis
BI364_11195	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BI364_11205	COG0835	chemotaxis
BI364_11220	COG1360	Flagellar Motor Protein
BI364_11225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BI364_11230	COG2201	protein-glutamate methylesterase activity
BI364_11240	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BI364_11265	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BI364_11280	COG1987	bacterial-type flagellum assembly
BI364_11310	COG0840	transmembrane signaling receptor activity
BI364_11315	COG0840	transmembrane signaling receptor activity
BI364_11320	COG0840	transmembrane signaling receptor activity
BI364_11360	COG1484	DNA-dependent DNA replication
BI364_11365	COG4584	PFAM Integrase catalytic
BI364_11370	COG1677	Flagellar hook-basal body complex protein FliE
BI364_11405	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BI364_11425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BI364_11440	COG1706	bacterial-type flagellum-dependent cell motility
BI364_11460	COG1749	Flagellar hook protein flgE
BI364_11465	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BI364_11470	COG1558	bacterial-type flagellum-dependent cell motility
BI364_11485	COG0741	lytic transglycosylase activity
BI364_11505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BI364_11545	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BI364_11560	COG1131	(ABC) transporter
BI364_11620	COG1442	glycosyl transferase family 8
BI364_11675	COG0367	asparagine synthase
BI364_11680	COG0297	glycogen (starch) synthase activity
BI364_11700	COG3409	Peptidoglycan-binding domain 1 protein
BI364_11700	COG3267	Type II secretory pathway component ExeA
BI364_11710	COG0489	protein tyrosine kinase activity
BI364_11725	COG0729	surface antigen
BI364_11750	COG2201	protein-glutamate methylesterase activity
BI364_11755	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BI364_11765	COG0835	chemotaxis
BI364_11770	COG0840	transmembrane signaling receptor activity
BI364_11775	COG0643	Histidine kinase
BI364_11775	COG2198	Histidine kinase
BI364_11785	COG0745	RESPONSE REGULATOR receiver
BI364_11790	COG0840	transmembrane signaling receptor activity
BI364_11795	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BI364_11800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BI364_11805	COG1428	Deoxynucleoside kinase
BI364_11840	COG2983	Belongs to the UPF0260 family
BI364_11870	COG0438	transferase activity, transferring glycosyl groups
BI364_11870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BI364_11895	COG0326	Molecular chaperone. Has ATPase activity
BI364_11920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BI364_11930	COG0335	large ribosomal subunit rRNA binding
BI364_11935	COG0336	Belongs to the RNA methyltransferase TrmD family
BI364_11940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BI364_11945	COG0228	four-way junction DNA binding
BI364_11950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BI364_11960	COG4536	flavin adenine dinucleotide binding
BI364_11980	COG1592	Rubrerythrin
BI364_11985	COG1722	exodeoxyribonuclease VII activity
BI364_11990	COG0142	geranyltranstransferase activity
BI364_12000	COG0720	synthase
BI364_12005	COG1469	GTP cyclohydrolase I activity
BI364_12015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BI364_12020	COG2716	regulation of RNA biosynthetic process
BI364_12025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BI364_12030	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BI364_12085	COG0442	prolyl-tRNA aminoacylation
BI364_12090	COG1254	Belongs to the acylphosphatase family
BI364_12095	COG1295	ribonuclease BN
BI364_12095	COG1959	2 iron, 2 sulfur cluster binding
BI364_12100	COG1295	ribonuclease BN
BI364_12100	COG1959	2 iron, 2 sulfur cluster binding
BI364_12135	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BI364_12140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BI364_12150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BI364_12160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BI364_12170	COG0765	amino acid transport
BI364_12175	COG1126	abc transporter atp-binding protein
BI364_12185	COG0312	modulator of DNA gyrase
BI364_12195	COG0312	modulator of DNA gyrase
BI364_12215	COG1530	ribonuclease E activity
BI364_12220	COG0424	maF-like protein
BI364_12225	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BI364_12235	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BI364_12240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BI364_12255	COG0495	leucyl-tRNA aminoacylation
BI364_12270	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BI364_12275	COG4535	Mg2 and Co2 transporter CorC
BI364_12280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BI364_12285	COG1702	phosphate starvation-inducible protein PhoH
BI364_12290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BI364_12325	COG0675	Transposase, IS605 OrfB family
BI364_12340	COG4691	Plasmid stability protein
BI364_12360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BI364_12380	COG0297	glycogen (starch) synthase activity
BI364_12380	COG0438	transferase activity, transferring glycosyl groups
BI364_12395	COG1216	Glycosyl transferase, family 2
BI364_12395	COG0438	transferase activity, transferring glycosyl groups
BI364_12415	COG2226	methyltransferase
BI364_12520	COG2814	Major facilitator Superfamily
BI364_12525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BI364_12530	COG0675	Transposase, IS605 OrfB family
BI364_12545	COG0203	ribosomal protein L17
BI364_12550	COG0202	RNA polymerase activity
BI364_12555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BI364_12565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BI364_12570	COG0201	protein transport
BI364_12575	COG0200	Binds to the 23S rRNA
BI364_12585	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BI364_12590	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BI364_12595	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BI364_12600	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BI364_12605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BI364_12610	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BI364_12615	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BI364_12620	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BI364_12625	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BI364_12630	COG0255	Belongs to the universal ribosomal protein uL29 family
BI364_12635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BI364_12640	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BI364_12645	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BI364_12650	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BI364_12655	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BI364_12660	COG0089	rRNA binding
BI364_12665	COG0088	Forms part of the polypeptide exit tunnel
BI364_12670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BI364_12675	COG0051	transcription antitermination factor activity, RNA binding
BI364_12680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BI364_12685	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BI364_12690	COG0049	tRNA binding
BI364_12695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BI364_12700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BI364_12705	COG0085	RNA polymerase activity
BI364_12710	COG0222	ribosome binding
BI364_12715	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BI364_12720	COG0081	regulation of translation
BI364_12725	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BI364_12745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BI364_12770	COG0768	penicillin binding
BI364_12775	COG1686	Belongs to the peptidase S11 family
BI364_12780	COG0772	Belongs to the SEDS family
BI364_12795	COG0084	hydrolase, TatD family'
BI364_12800	COG0271	Belongs to the BolA IbaG family
BI364_12805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BI364_12815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BI364_12835	COG2210	Belongs to the sulfur carrier protein TusA family
BI364_12845	COG1940	carbohydrate kinase activity
BI364_12850	COG2096	Adenosyltransferase
BI364_12860	COG2200	EAL domain
BI364_12865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BI364_12885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BI364_12915	COG3039	Transposase
BI364_12960	COG2205	protein histidine kinase activity
BI364_12975	COG3706	GGDEF domain
BI364_12980	COG3384	dioxygenase
BI364_12985	COG0400	carboxylic ester hydrolase activity
BI364_12995	COG0765	amino acid transport
BI364_13000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BI364_13015	COG1956	GAF domain-containing protein
BI364_13045	COG1247	-acetyltransferase
BI364_13050	COG1484	DNA-dependent DNA replication
BI364_13055	COG4584	PFAM Integrase catalytic
BI364_13065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BI364_13070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BI364_13075	COG0346	lactoylglutathione lyase activity
BI364_13100	COG1584	GPR1 FUN34 yaaH family protein
BI364_13140	COG0628	permease
BI364_13145	COG1881	PFAM PEBP family protein
BI364_13195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BI364_13235	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BI364_13245	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BI364_13255	COG2921	Belongs to the UPF0250 family
BI364_13270	COG2951	lytic endotransglycosylase activity
BI364_13275	COG0772	Belongs to the SEDS family
BI364_13280	COG0768	penicillin binding
BI364_13285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BI364_13290	COG0563	adenylate kinase activity
BI364_13295	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BI364_13300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BI364_13305	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BI364_13315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BI364_13325	COG0837	glucose binding
BI364_13330	COG2967	ApaG domain
BI364_13335	COG4106	trans-aconitate 2-methyltransferase activity
BI364_13340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BI364_13360	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BI364_13365	COG0527	aspartate kinase activity
BI364_13370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BI364_13375	COG2137	regulation of response to DNA damage stimulus
BI364_13380	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BI364_13390	COG1546	Belongs to the CinA family
BI364_13410	COG0531	amino acid
BI364_13420	COG4584	PFAM Integrase catalytic
BI364_13425	COG1484	DNA-dependent DNA replication
BI364_13435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BI364_13435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BI364_13465	COG2608	mercury ion transmembrane transporter activity
BI364_13525	COG3039	Transposase
BI364_13555	COG2801	Transposase and inactivated derivatives
BI364_13560	COG1742	UPF0060 membrane protein
BI364_13615	COG2217	Heavy metal translocating P-type atpase
BI364_13635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BI364_13655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BI364_13725	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BI364_13735	COG1366	Belongs to the anti-sigma-factor antagonist family
BI364_13750	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BI364_13755	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BI364_13765	COG0095	Lipoate-protein ligase
BI364_13775	COG0509	glycine decarboxylation via glycine cleavage system
BI364_13785	COG0509	glycine decarboxylation via glycine cleavage system
BI364_13790	COG2048	Heterodisulfide reductase, subunit B
BI364_13830	COG4783	chaperone-mediated protein folding
BI364_13870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BI364_13875	COG1160	GTP binding
BI364_13880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BI364_13885	COG3850	Histidine kinase
BI364_13885	COG0642	Histidine kinase
BI364_13895	COG2943	transferase activity, transferring hexosyl groups
BI364_13895	COG3416	Protein conserved in bacteria
BI364_13930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BI364_13935	COG0625	glutathione transferase activity
BI364_13970	COG0004	ammonium transporteR
BI364_13975	COG0717	Belongs to the dCTP deaminase family
BI364_13980	COG0489	protein tyrosine kinase activity
BI364_13985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BI364_13985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BI364_13990	COG1028	Short-chain dehydrogenase reductase Sdr
BI364_13995	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BI364_14005	COG0235	Class ii aldolase
BI364_14010	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BI364_14015	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BI364_14040	COG2878	Part of a membrane complex involved in electron transport
BI364_14050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BI364_14075	COG0004	ammonium transporteR
BI364_14080	COG1968	undecaprenyl-diphosphatase activity
BI364_14100	COG0483	inositol monophosphate 1-phosphatase activity
BI364_14105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BI364_14120	COG0435	Glutathione S-transferase
BI364_14125	COG2259	Doxx family
BI364_14130	COG0662	Cupin 2, conserved barrel domain protein
BI364_14135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BI364_14140	COG0456	acetyltransferase
BI364_14185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BI364_14190	COG0602	queuosine metabolic process
BI364_14195	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BI364_14205	COG0823	Involved in the tonB-independent uptake of proteins
BI364_14220	COG0811	peptide transport
BI364_14225	COG0824	Thioesterase
BI364_14230	COG2204	response regulator
BI364_14240	COG2205	protein histidine kinase activity
BI364_14250	COG2255	four-way junction helicase activity
BI364_14255	COG0632	four-way junction helicase activity
BI364_14260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BI364_14265	COG0217	transcriptional regulatory protein
BI364_14275	COG0494	nUDIX hydrolase
BI364_14280	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BI364_14300	COG0300	oxidoreductase activity
BI364_14315	COG0542	response to heat
BI364_14325	COG0242	peptide deformylase activity
BI364_14330	COG3830	Belongs to the UPF0237 family
BI364_14355	COG0778	Nitroreductase
BI364_14370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BI364_14375	COG0045	succinate-CoA ligase (ADP-forming) activity
BI364_14425	COG0438	transferase activity, transferring glycosyl groups
BI364_14450	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BI364_14455	COG0237	dephospho-CoA kinase activity
BI364_14470	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BI364_14485	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BI364_14490	COG0653	protein targeting
BI364_14495	COG1196	nuclear chromosome segregation
BI364_14495	COG0741	lytic transglycosylase activity
BI364_14495	COG0739	heme binding
BI364_14500	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BI364_14510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BI364_14525	COG1181	Belongs to the D-alanine--D-alanine ligase family
BI364_14535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BI364_14540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BI364_14545	COG0772	Belongs to the SEDS family
BI364_14550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BI364_14555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BI364_14560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BI364_14565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BI364_14575	COG3116	cell division
BI364_14580	COG0275	rRNA processing
BI364_14585	COG2001	Belongs to the MraZ family
BI364_14600	COG3107	peptidoglycan biosynthetic process
BI364_14605	COG0792	nuclease activity
BI364_14610	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BI364_14615	COG0277	FAD linked oxidase domain protein
BI364_14620	COG2969	positive regulation of protein catabolic process
BI364_14625	COG0625	glutathione transferase activity
BI364_14630	COG2857	Cytochrome c1
BI364_14635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BI364_14640	COG0723	plastoquinol--plastocyanin reductase activity
BI364_14650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BI364_14655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BI364_14665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BI364_14675	COG2854	intermembrane phospholipid transfer
BI364_14680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BI364_14685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BI364_14690	COG1127	ABC transporter
BI364_14720	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BI364_14735	COG1137	ATPase activity
BI364_14750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BI364_14760	COG1660	Displays ATPase and GTPase activities
BI364_14770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BI364_14775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BI364_14780	COG2239	Acts as a magnesium transporter
BI364_14810	COG1773	rubredoxin
BI364_14815	COG0351	phosphomethylpyrimidine kinase
BI364_14820	COG0352	thiamine-phosphate diphosphorylase activity
BI364_14830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BI364_14850	COG0659	secondary active sulfate transmembrane transporter activity
BI364_14870	COG1017	nitric oxide dioxygenase activity
BI364_14870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BI364_14880	COG0583	DNA-binding transcription factor activity
BI364_14885	COG1741	Belongs to the pirin family
BI364_14895	COG0604	alcohol dehydrogenase
BI364_14905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BI364_14940	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BI364_14965	COG5001	Diguanylate cyclase
BI364_14965	COG5002	protein histidine kinase activity
BI364_15025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BI364_15030	COG1074	ATP-dependent DNA helicase activity
BI364_15035	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BI364_15040	COG0668	transmembrane transport
BI364_15070	COG2022	thiamine diphosphate biosynthetic process
BI364_15075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BI364_15080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BI364_15085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BI364_15090	COG0438	transferase activity, transferring glycosyl groups
BI364_15095	COG0438	transferase activity, transferring glycosyl groups
BI364_15110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BI364_15115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BI364_15120	COG1333	cytochrome c biogenesis protein
BI364_15140	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BI364_15145	COG1611	Belongs to the LOG family
BI364_15170	COG0210	DNA helicase
BI364_15195	COG2857	Cytochrome c1
BI364_15200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BI364_15205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BI364_15210	COG0723	plastoquinol--plastocyanin reductase activity
BI364_15225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BI364_15235	COG0109	protoheme IX farnesyltransferase activity
BI364_15255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BI364_15280	COG0745	RESPONSE REGULATOR receiver
BI364_15285	COG1217	gtp-binding protein TYPA
BI364_15290	COG2346	COG2346, Truncated hemoglobins
BI364_15305	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BI364_15310	COG0830	nickel cation binding
BI364_15315	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BI364_15340	COG1335	isochorismatase
BI364_15355	COG0251	oxidation-reduction process
BI364_15370	COG0667	Aldo Keto reductase
BI364_15375	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BI364_15415	COG2204	response regulator
BI364_15440	COG1028	Short-chain dehydrogenase reductase Sdr
BI364_15470	COG0010	Belongs to the arginase family
BI364_15505	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BI364_15515	COG1280	lysine exporter protein (LysE YggA)
BI364_15535	COG1139	Iron-sulfur cluster binding protein
BI364_15540	COG0247	lactate metabolic process
BI364_15545	COG2130	NADP-dependent
BI364_15550	COG1979	alcohol dehydrogenase
BI364_15590	COG0832	Belongs to the urease beta subunit family
BI364_15595	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BI364_15600	COG0831	urea catabolic process
BI364_15605	COG0829	nickel cation binding
BI364_15610	COG3100	YcgL domain-containing protein
BI364_15620	COG1166	arginine decarboxylase activity
BI364_15625	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BI364_15630	COG0640	Transcriptional regulator
BI364_15635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BI364_15640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BI364_15650	COG0390	transport system, permease component
BI364_15660	COG0004	ammonium transporteR
BI364_15675	COG2960	long-chain fatty acid transporting porin activity
BI364_15680	COG0606	chelatase, subunit chli
BI364_15685	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BI364_15725	COG3039	Transposase
BI364_15745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BI364_15750	COG0606	chelatase, subunit chli
BI364_15760	COG1126	abc transporter atp-binding protein
BI364_15765	COG0765	amino acid transport
BI364_15770	COG4597	amino acid ABC transporter
BI364_15775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BI364_15795	COG0559	Belongs to the binding-protein-dependent transport system permease family
BI364_15810	COG2095	MarC family integral membrane protein
BI364_15890	COG0456	acetyltransferase
BI364_15890	COG1214	PFAM Peptidase M22, glycoprotease
BI364_15950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BI364_15955	COG3842	ATPase activity
BI364_16000	COG0848	biopolymer transport protein
BI364_16005	COG0811	peptide transport
BI364_16020	COG0745	RESPONSE REGULATOR receiver
BI364_16035	COG0745	RESPONSE REGULATOR receiver
BI364_16040	COG3706	GGDEF domain
BI364_16040	COG2203	Gaf domain
BI364_16040	COG5001	Diguanylate cyclase
BI364_16040	COG4251	negative regulation of phosphorylation
BI364_16050	COG3273	potassium ion transport
BI364_16050	COG0471	metal ion transport
BI364_16055	COG3954	Phosphoribulokinase
BI364_16070	COG0667	Aldo Keto reductase
BI364_16080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BI364_16085	COG0730	response to heat
BI364_16105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BI364_16110	COG0751	glycine-tRNA ligase activity
BI364_16125	COG0482	sulfurtransferase activity
BI364_16135	COG1230	cation diffusion facilitator family transporter
BI364_16140	COG0174	glutamine synthetase
BI364_16150	COG3852	Histidine kinase
BI364_16160	COG0167	dihydroorotate dehydrogenase activity
BI364_16165	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BI364_16170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BI364_16175	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BI364_16185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BI364_16195	COG4942	peptidase
BI364_16200	COG0793	Belongs to the peptidase S41A family
BI364_16205	COG2861	carbohydrate metabolic process
BI364_16210	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BI364_16215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BI364_16235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BI364_16260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BI364_16280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BI364_16295	COG0463	Glycosyl transferase, family 2
BI364_16340	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BI364_16365	COG0745	RESPONSE REGULATOR receiver
BI364_16390	COG3706	GGDEF domain
BI364_16430	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BI364_16460	COG1643	Atp-dependent helicase
BI364_16465	COG2818	Glycosylase
BI364_16490	COG0018	arginyl-trna synthetase
BI364_16495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BI364_16520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BI364_16535	COG0456	acetyltransferase
BI364_16545	COG0205	6-phosphofructokinase activity
BI364_16550	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BI364_16565	COG1569	PIN domain
BI364_16570	COG3311	Transcriptional regulator
BI364_16585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BI364_16605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BI364_16610	COG0384	phenazine biosynthesis protein PhzF
BI364_16615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BI364_16640	COG0667	Aldo Keto reductase
BI364_16645	COG5001	Diguanylate cyclase
BI364_16645	COG3300	MHYT domain
BI364_16655	COG0142	geranyltranstransferase activity
BI364_16660	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BI364_16665	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BI364_16670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BI364_16675	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BI364_16680	COG0268	Binds directly to 16S ribosomal RNA
BI364_16685	COG0728	peptidoglycan biosynthetic process
BI364_16690	COG2204	response regulator
BI364_16720	COG0196	riboflavin kinase activity
BI364_16725	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BI364_16730	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BI364_16735	COG1187	pseudouridine synthase activity
BI364_16740	COG0247	lactate metabolic process
BI364_16745	COG0277	FAD linked oxidase domain protein
BI364_16750	COG0277	FAD linked oxidase domain protein
BI364_16755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BI364_16760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BI364_16765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BI364_16780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BI364_16790	COG0493	'glutamate synthase
BI364_16790	COG0543	2 iron, 2 sulfur cluster binding
BI364_16815	COG2188	Transcriptional regulator
BI364_16825	COG0583	DNA-binding transcription factor activity
BI364_16830	COG1959	2 iron, 2 sulfur cluster binding
BI364_16855	COG0123	including yeast histone deacetylase and acetoin utilization protein
BI364_16865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BI364_16875	COG3158	transport of potassium into the cell
BI364_16895	COG0604	alcohol dehydrogenase
BI364_16900	COG2067	long-chain fatty acid transport protein
BI364_16915	COG1192	Involved in chromosome partitioning
BI364_16955	COG1566	PFAM secretion protein HlyD family protein
BI364_16960	COG2814	Major facilitator Superfamily
BI364_16965	COG0589	response to stress
BI364_16975	COG1047	Peptidyl-prolyl cis-trans
BI364_16980	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BI364_17030	COG3001	Fructosamine kinase
BI364_17050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BI364_17055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BI364_17060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BI364_17065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BI364_17070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BI364_17075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BI364_17080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BI364_17085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BI364_17090	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BI364_17095	COG0356	it plays a direct role in the translocation of protons across the membrane
BI364_17105	COG1475	DNA binding
BI364_17110	COG1192	Involved in chromosome partitioning
BI364_17115	COG0357	Ribosomal RNA small subunit methyltransferase G
BI364_17125	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BI364_17130	COG0706	membrane insertase activity
BI364_17135	COG0594	ribonuclease P activity
BI364_17140	COG0230	Belongs to the bacterial ribosomal protein bL34 family