locus-tag	class	description
Acry_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Acry_0002	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Acry_0003	COG1278	Cold shock
Acry_0004	COG0789	Transcriptional regulator
Acry_0005	COG0183	Belongs to the thiolase family
Acry_0006	COG1250	3-hydroxyacyl-CoA dehydrogenase
Acry_0006	COG1024	Enoyl-CoA hydratase
Acry_0007	COG1960	acyl-CoA dehydrogenase activity
Acry_0010	COG0725	ABC transporter, periplasmic molybdate-binding protein
Acry_0012	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Acry_0015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Acry_0016	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Acry_0017	COG0235	Class ii aldolase
Acry_0018	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Acry_0019	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
Acry_0020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Acry_0021	COG1396	sequence-specific DNA binding
Acry_0022	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Acry_0024	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Acry_0026	COG3045	CreA protein
Acry_0027	COG0138	bifunctional purine biosynthesis protein purh
Acry_0029	COG0187	DNA topoisomerase II activity
Acry_0030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Acry_0031	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Acry_0034	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Acry_0037	COG0557	exoribonuclease II activity
Acry_0038	COG0793	Belongs to the peptidase S41A family
Acry_0039	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Acry_0040	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Acry_0041	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Acry_0043	COG2010	Cytochrome c
Acry_0043	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Acry_0044	COG0156	8-amino-7-oxononanoate synthase activity
Acry_0045	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Acry_0047	COG1192	Involved in chromosome partitioning
Acry_0048	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Acry_0048	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Acry_0049	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Acry_0050	COG0509	glycine decarboxylation via glycine cleavage system
Acry_0051	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Acry_0051	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Acry_0053	COG0616	signal peptide processing
Acry_0054	COG2001	Belongs to the MraZ family
Acry_0055	COG0275	rRNA processing
Acry_0058	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Acry_0059	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Acry_0060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Acry_0061	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Acry_0063	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Acry_0064	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Acry_0065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Acry_0066	COG1181	Belongs to the D-alanine--D-alanine ligase family
Acry_0067	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Acry_0068	COG0849	cell division
Acry_0069	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Acry_0071	COG0658	competence protein
Acry_0071	COG2333	competence protein COMEC
Acry_0073	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Acry_0078	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Acry_0079	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
Acry_0080	COG0535	radical SAM domain protein
Acry_0081	COG0535	radical SAM domain protein
Acry_0082	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Acry_0085	COG1335	isochorismatase
Acry_0086	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_0087	COG0129	dihydroxy-acid dehydratase activity
Acry_0089	COG0789	Transcriptional regulator
Acry_0090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Acry_0091	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Acry_0094	COG3327	negative regulation of DNA-templated transcription, initiation
Acry_0098	COG3328	transposase activity
Acry_0100	COG3293	Transposase
Acry_0108	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Acry_0113	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Acry_0117	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Acry_0118	COG1562	ergosterol biosynthetic process
Acry_0119	COG1562	ergosterol biosynthetic process
Acry_0120	COG1215	transferase activity, transferring glycosyl groups
Acry_0121	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Acry_0123	COG2261	transglycosylase associated protein
Acry_0128	COG0181	hydroxymethylbilane synthase activity
Acry_0129	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Acry_0130	COG0058	SHG alpha-glucan phosphorylase activity
Acry_0131	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Acry_0132	COG0297	glycogen (starch) synthase activity
Acry_0134	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Acry_0135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Acry_0136	COG1538	Outer membrane efflux protein
Acry_0139	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Acry_0140	COG0247	lactate metabolic process
Acry_0141	COG3158	transport of potassium into the cell
Acry_0144	COG1042	CoA-binding domain protein
Acry_0144	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Acry_0144	COG0045	succinate-CoA ligase (ADP-forming) activity
Acry_0145	COG0697	spore germination
Acry_0146	COG1250	3-hydroxyacyl-CoA dehydrogenase
Acry_0150	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Acry_0151	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Acry_0156	COG0556	nucleotide-excision repair
Acry_0160	COG5328	Belongs to the UPF0262 family
Acry_0161	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Acry_0163	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Acry_0164	COG0564	pseudouridine synthase activity
Acry_0167	COG0148	phosphopyruvate hydratase activity
Acry_0169	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Acry_0171	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Acry_0173	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Acry_0173	COG2885	chlorophyll binding
Acry_0174	COG2885	chlorophyll binding
Acry_0174	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Acry_0175	COG2365	Tyrosine phosphatase family
Acry_0178	COG0469	pyruvate kinase activity
Acry_0180	COG3750	Belongs to the UPF0335 family
Acry_0181	COG0113	porphobilinogen synthase activity
Acry_0185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Acry_0186	COG1609	Transcriptional regulator
Acry_0187	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Acry_0187	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Acry_0188	COG1105	Belongs to the carbohydrate kinase PfkB family
Acry_0189	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Acry_0189	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Acry_0191	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Acry_0193	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Acry_0195	COG0477	Major facilitator Superfamily
Acry_0196	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Acry_0198	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Acry_0199	COG0501	Belongs to the peptidase M48B family
Acry_0200	COG0071	Belongs to the small heat shock protein (HSP20) family
Acry_0207	COG1132	(ABC) transporter
Acry_0210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Acry_0212	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Acry_0213	COG4133	protoheme IX ABC transporter activity
Acry_0214	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Acry_0215	COG0006	proline dipeptidase activity
Acry_0217	COG2264	protein methyltransferase activity
Acry_0218	COG0210	DNA helicase
Acry_0219	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Acry_0220	COG2853	Lipoprotein
Acry_0222	COG0779	Required for maturation of 30S ribosomal subunits
Acry_0225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Acry_0226	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Acry_0227	COG0009	L-threonylcarbamoyladenylate synthase
Acry_0228	COG0438	transferase activity, transferring glycosyl groups
Acry_0230	COG4214	carbohydrate transport
Acry_0231	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Acry_0232	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Acry_0233	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Acry_0237	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Acry_0239	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Acry_0240	COG0625	glutathione transferase activity
Acry_0241	COG0406	alpha-ribazole phosphatase activity
Acry_0242	COG1454	alcohol dehydrogenase
Acry_0245	COG2226	methyltransferase
Acry_0246	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Acry_0248	COG1686	Belongs to the peptidase S11 family
Acry_0250	COG0571	ribonuclease III activity
Acry_0251	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Acry_0252	COG1960	acyl-CoA dehydrogenase activity
Acry_0253	COG1960	acyl-CoA dehydrogenase activity
Acry_0254	COG0318	PFAM AMP-dependent synthetase and ligase
Acry_0255	COG1024	Enoyl-CoA hydratase
Acry_0255	COG1250	3-hydroxyacyl-CoA dehydrogenase
Acry_0258	COG0457	Tetratricopeptide repeat
Acry_0264	COG0438	transferase activity, transferring glycosyl groups
Acry_0266	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Acry_0268	COG0776	regulation of translation
Acry_0269	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Acry_0270	COG0416	fatty acid biosynthetic process
Acry_0271	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Acry_0275	COG0582	viral genome integration into host DNA
Acry_0282	COG1484	DNA-dependent DNA replication
Acry_0283	COG4584	PFAM Integrase catalytic
Acry_0287	COG3328	transposase activity
Acry_0289	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Acry_0293	COG0110	maltose O-acetyltransferase activity
Acry_0296	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Acry_0299	COG3842	ATPase activity
Acry_0302	COG1136	(ABC) transporter
Acry_0304	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Acry_0305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Acry_0306	COG1136	(ABC) transporter
Acry_0306	COG0577	efflux transmembrane transporter activity
Acry_0307	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Acry_0312	COG2205	protein histidine kinase activity
Acry_0318	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_0319	COG1129	ABC transporter
Acry_0323	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
Acry_0325	COG0384	phenazine biosynthesis protein PhzF
Acry_0327	COG0409	Hydrogenase expression formation protein
Acry_0332	COG1773	rubredoxin
Acry_0341	COG1575	Belongs to the MenA family. Type 1 subfamily
Acry_0345	COG0243	molybdopterin cofactor binding
Acry_0346	COG2897	thiosulfate sulfurtransferase activity
Acry_0350	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
Acry_0353	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Acry_0354	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Acry_0354	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Acry_0355	COG2326	polyphosphate kinase activity
Acry_0359	COG0559	Belongs to the binding-protein-dependent transport system permease family
Acry_0361	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Acry_0361	COG0072	phenylalanine-tRNA ligase activity
Acry_0362	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Acry_0363	COG2885	chlorophyll binding
Acry_0365	COG0037	tRNA processing
Acry_0366	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Acry_0369	COG1185	polyribonucleotide nucleotidyltransferase activity
Acry_0370	COG2807	transmembrane transport
Acry_0372	COG2259	Doxx family
Acry_0373	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Acry_0374	COG0242	peptide deformylase activity
Acry_0376	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Acry_0377	COG0004	ammonium transporteR
Acry_0378	COG1674	ftsk spoiiie
Acry_0381	COG0352	thiamine-phosphate diphosphorylase activity
Acry_0383	COG0457	Tetratricopeptide repeat
Acry_0383	COG0463	Glycosyl transferase, family 2
Acry_0388	COG1530	ribonuclease E activity
Acry_0391	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Acry_0392	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Acry_0393	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Acry_0394	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Acry_0395	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Acry_0396	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Acry_0397	COG0356	it plays a direct role in the translocation of protons across the membrane
Acry_0399	COG1196	nuclear chromosome segregation
Acry_0401	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Acry_0404	COG1286	toxin biosynthetic process
Acry_0405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Acry_0406	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Acry_0408	COG0071	Belongs to the small heat shock protein (HSP20) family
Acry_0409	COG0242	peptide deformylase activity
Acry_0410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Acry_0411	COG0101	tRNA pseudouridine synthase activity
Acry_0412	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Acry_0416	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Acry_0417	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Acry_0419	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Acry_0420	COG0322	excinuclease ABC activity
Acry_0425	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Acry_0428	COG0424	maF-like protein
Acry_0431	COG2983	Belongs to the UPF0260 family
Acry_0435	COG1131	(ABC) transporter
Acry_0436	COG2813	Specifically methylates the guanine in position
Acry_0436	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Acry_0437	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Acry_0438	COG1605	Chorismate mutase
Acry_0438	COG0077	Prephenate dehydratase
Acry_0439	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Acry_0440	COG0287	Prephenate dehydrogenase
Acry_0441	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Acry_0442	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Acry_0443	COG0670	Belongs to the BI1 family
Acry_0444	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Acry_0445	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Acry_0445	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Acry_0446	COG1660	Displays ATPase and GTPase activities
Acry_0450	COG0745	RESPONSE REGULATOR receiver
Acry_0451	COG2205	protein histidine kinase activity
Acry_0452	COG2814	Major facilitator Superfamily
Acry_0456	COG1069	ribulokinase activity
Acry_0457	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Acry_0463	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_0465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Acry_0466	COG0129	dihydroxy-acid dehydratase activity
Acry_0467	COG0800	Aldolase
Acry_0468	COG2814	Major facilitator Superfamily
Acry_0471	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Acry_0474	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Acry_0478	COG2050	protein possibly involved in aromatic compounds catabolism
Acry_0481	COG4964	Belongs to the GSP D family
Acry_0483	COG0559	Belongs to the binding-protein-dependent transport system permease family
Acry_0485	COG0410	ABC transporter
Acry_0490	COG5001	Diguanylate cyclase
Acry_0490	COG3300	MHYT domain
Acry_0494	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_0495	COG4689	acetoacetate decarboxylase
Acry_0497	COG0768	penicillin binding
Acry_0502	COG1070	Carbohydrate kinase
Acry_0503	COG1879	ABC-type sugar transport system periplasmic component
Acry_0504	COG1129	ABC transporter
Acry_0505	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_0506	COG0776	regulation of translation
Acry_0507	COG1091	dTDP-4-dehydrorhamnose reductase activity
Acry_0509	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Acry_0510	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Acry_0511	COG2080	2 iron, 2 sulfur cluster binding
Acry_0513	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Acry_0515	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Acry_0520	COG0840	transmembrane signaling receptor activity
Acry_0522	COG5001	Diguanylate cyclase
Acry_0526	COG1199	ATP-dependent helicase activity
Acry_0527	COG1573	uracil-dna glycosylase
Acry_0529	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Acry_0530	COG1758	RNA polymerase activity
Acry_0532	COG0736	holo-[acyl-carrier-protein] synthase activity
Acry_0533	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Acry_0534	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Acry_0535	COG0596	Alpha beta hydrolase
Acry_0537	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Acry_0539	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Acry_0540	COG1177	transmembrane transport
Acry_0541	COG1176	ABC-type spermidine putrescine transport system, permease component I
Acry_0542	COG3842	ATPase activity
Acry_0543	COG0686	Belongs to the AlaDH PNT family
Acry_0546	COG0174	glutamine synthetase
Acry_0548	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Acry_0548	COG0662	Cupin 2, conserved barrel domain protein
Acry_0553	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Acry_0554	COG4988	ABC transporter
Acry_0555	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Acry_0559	COG4178	(ABC) transporter
Acry_0561	COG1566	PFAM secretion protein HlyD family protein
Acry_0562	COG2814	Major facilitator Superfamily
Acry_0563	COG1538	Outer membrane efflux protein
Acry_0564	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Acry_0565	COG0538	isocitrate dehydrogenase activity
Acry_0566	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Acry_0567	COG3706	GGDEF domain
Acry_0567	COG0745	RESPONSE REGULATOR receiver
Acry_0574	COG0745	RESPONSE REGULATOR receiver
Acry_0577	COG0745	RESPONSE REGULATOR receiver
Acry_0578	COG0784	Response regulator, receiver
Acry_0578	COG4191	Histidine kinase
Acry_0581	COG1396	sequence-specific DNA binding
Acry_0581	COG3800	Transcriptional regulator
Acry_0582	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Acry_0583	COG0196	riboflavin kinase activity
Acry_0584	COG2030	dehydratase
Acry_0587	COG0477	Major facilitator Superfamily
Acry_0588	COG1132	(ABC) transporter
Acry_0591	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Acry_0593	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Acry_0596	COG1090	epimerase
Acry_0599	COG0840	transmembrane signaling receptor activity
Acry_0605	COG0651	ATP synthesis coupled electron transport
Acry_0606	COG0649	NAD binding
Acry_0607	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Acry_0611	COG1091	dTDP-4-dehydrorhamnose reductase activity
Acry_0612	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Acry_0613	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Acry_0614	COG1088	dTDP-glucose 4,6-dehydratase activity
Acry_0616	COG0154	amidase activity
Acry_0617	COG0415	Belongs to the DNA photolyase family
Acry_0618	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_0619	COG0318	PFAM AMP-dependent synthetase and ligase
Acry_0620	COG2079	MmgE PrpD family protein
Acry_0622	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Acry_0623	COG1960	acyl-CoA dehydrogenase activity
Acry_0624	COG1024	Enoyl-CoA hydratase
Acry_0628	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Acry_0630	COG2814	Major facilitator Superfamily
Acry_0632	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Acry_0633	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Acry_0638	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Acry_0639	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Acry_0642	COG1605	Chorismate mutase
Acry_0642	COG0077	Prephenate dehydratase
Acry_0643	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Acry_0644	COG3474	cytochrome
Acry_0645	COG0483	inositol monophosphate 1-phosphatase activity
Acry_0647	COG0473	3-isopropylmalate dehydrogenase activity
Acry_0648	COG0531	amino acid
Acry_0650	COG1663	tetraacyldisaccharide 4'-kinase activity
Acry_0651	COG1519	Transferase
Acry_0656	COG1792	Involved in formation and maintenance of cell shape
Acry_0659	COG0772	Belongs to the SEDS family
Acry_0660	COG1017	nitric oxide dioxygenase activity
Acry_0660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Acry_0662	COG0318	PFAM AMP-dependent synthetase and ligase
Acry_0664	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Acry_0665	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Acry_0673	COG2885	chlorophyll binding
Acry_0676	COG1309	transcriptional regulator
Acry_0677	COG0583	DNA-binding transcription factor activity
Acry_0678	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Acry_0681	COG0840	transmembrane signaling receptor activity
Acry_0684	COG0765	amino acid transport
Acry_0686	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Acry_0697	COG0123	including yeast histone deacetylase and acetoin utilization protein
Acry_0698	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Acry_0707	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Acry_0708	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Acry_0713	COG2205	protein histidine kinase activity
Acry_0715	COG0583	DNA-binding transcription factor activity
Acry_0716	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_0717	COG3959	Transketolase, thiamine diphosphate binding domain
Acry_0718	COG3958	Transketolase
Acry_0719	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Acry_0720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Acry_0723	COG1968	undecaprenyl-diphosphatase activity
Acry_0724	COG0463	Glycosyl transferase, family 2
Acry_0725	COG2166	iron-sulfur cluster assembly
Acry_0726	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Acry_0728	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Acry_0729	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Acry_0730	COG0758	DNA mediated transformation
Acry_0733	COG0540	Belongs to the ATCase OTCase family
Acry_0736	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Acry_0739	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Acry_0739	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Acry_0744	COG0019	diaminopimelate decarboxylase activity
Acry_0745	COG0165	Argininosuccinate lyase
Acry_0746	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Acry_0747	COG0137	argininosuccinate synthase activity
Acry_0750	COG1160	GTP binding
Acry_0754	COG0539	negative regulation of cytoplasmic translation
Acry_0755	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Acry_0756	COG0497	DNA recombination
Acry_0757	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Acry_0758	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Acry_0760	COG1706	bacterial-type flagellum-dependent cell motility
Acry_0763	COG0438	transferase activity, transferring glycosyl groups
Acry_0767	COG0390	transport system, permease component
Acry_0768	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Acry_0769	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Acry_0770	COG2154	pterin-4-alpha-carbinolamine dehydratase
Acry_0776	COG3328	transposase activity
Acry_0779	COG2963	transposase activity
Acry_0784	COG4372	Transposase
Acry_0785	COG3436	PFAM IS66 Orf2 family protein
Acry_0786	COG2963	transposase activity
Acry_0787	COG2801	Transposase and inactivated derivatives
Acry_0803	COG3012	SEC-C Motif Domain Protein
Acry_0804	COG2801	Transposase and inactivated derivatives
Acry_0805	COG3328	transposase activity
Acry_0806	COG2801	Transposase and inactivated derivatives
Acry_0816	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Acry_0817	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Acry_0818	COG0351	phosphomethylpyrimidine kinase
Acry_0819	COG1764	response to oxidative stress
Acry_0820	COG1192	Involved in chromosome partitioning
Acry_0821	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Acry_0824	COG1850	ribulose-bisphosphate carboxylase activity
Acry_0825	COG4451	ribulose bisphosphate carboxylase, small
Acry_0828	COG0402	S-adenosylhomocysteine deaminase activity
Acry_0829	COG0259	pyridoxamine-phosphate oxidase activity
Acry_0830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Acry_0832	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Acry_0838	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Acry_0839	COG3383	formate dehydrogenase (NAD+) activity
Acry_0842	COG0583	DNA-binding transcription factor activity
Acry_0843	COG1064	alcohol dehydrogenase
Acry_0845	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Acry_0847	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Acry_0850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Acry_0851	COG1846	Transcriptional regulator
Acry_0852	COG0745	RESPONSE REGULATOR receiver
Acry_0853	COG2205	protein histidine kinase activity
Acry_0856	COG0513	Belongs to the DEAD box helicase family
Acry_0859	COG3300	MHYT domain
Acry_0859	COG5001	Diguanylate cyclase
Acry_0861	COG0358	DNA primase activity
Acry_0862	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Acry_0865	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Acry_0869	COG1999	signal sequence binding
Acry_0870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Acry_0871	COG0154	amidase activity
Acry_0872	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Acry_0873	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Acry_0875	COG3772	lysozyme
Acry_0885	COG1450	Type ii and iii secretion system protein
Acry_0888	COG3166	PFAM Fimbrial assembly family protein
Acry_0893	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Acry_0899	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Acry_0899	COG0519	Catalyzes the synthesis of GMP from XMP
Acry_0900	COG0412	Dienelactone hydrolase
Acry_0901	COG0494	nUDIX hydrolase
Acry_0903	COG0793	Belongs to the peptidase S41A family
Acry_0905	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Acry_0906	COG0084	hydrolase, TatD family'
Acry_0907	COG1234	tRNA 3'-trailer cleavage
Acry_0908	COG2309	aminopeptidase activity
Acry_0909	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Acry_0910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Acry_0911	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Acry_0912	COG0505	Belongs to the CarA family
Acry_0913	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Acry_0914	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Acry_0916	COG0544	peptidyl-prolyl cis-trans isomerase activity
Acry_0917	COG0740	serine-type endopeptidase activity
Acry_0918	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Acry_0920	COG0776	regulation of translation
Acry_0921	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Acry_0922	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Acry_0923	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Acry_0924	COG0649	NAD binding
Acry_0925	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Acry_0927	COG1034	ATP synthesis coupled electron transport
Acry_0928	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Acry_0929	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Acry_0931	COG0713	ATP synthesis coupled electron transport
Acry_0934	COG1007	ATP synthesis coupled electron transport
Acry_0936	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Acry_0939	COG0442	prolyl-tRNA aminoacylation
Acry_0941	COG1136	(ABC) transporter
Acry_0943	COG3431	PFAM Phosphate-starvation-inducible E
Acry_0945	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Acry_0946	COG0708	Exodeoxyribonuclease III
Acry_0948	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Acry_0949	COG0018	arginyl-trna synthetase
Acry_0951	COG1472	Belongs to the glycosyl hydrolase 3 family
Acry_0952	COG1994	Peptidase M50
Acry_0953	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Acry_0954	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Acry_0955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Acry_0956	COG0805	protein transport
Acry_0957	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Acry_0961	COG0640	Transcriptional regulator
Acry_0962	COG2022	thiamine diphosphate biosynthetic process
Acry_0965	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Acry_0966	COG5001	Diguanylate cyclase
Acry_0966	COG3300	MHYT domain
Acry_0968	COG2951	lytic endotransglycosylase activity
Acry_0970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Acry_0976	COG0463	Glycosyl transferase, family 2
Acry_0979	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Acry_0980	COG0483	inositol monophosphate 1-phosphatase activity
Acry_0981	COG3842	ATPase activity
Acry_0989	COG3448	diguanylate cyclase activity
Acry_0989	COG4175	Glycine betaine
Acry_0990	COG1012	belongs to the aldehyde dehydrogenase family
Acry_0992	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Acry_0993	COG4311	Sarcosine oxidase, delta subunit
Acry_0994	COG0446	pyridine nucleotide-disulphide oxidoreductase
Acry_0994	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Acry_0996	COG1760	l-serine dehydratase
Acry_0999	COG2181	nitrate reductase activity
Acry_0999	COG0247	lactate metabolic process
Acry_1000	COG0446	pyridine nucleotide-disulphide oxidoreductase
Acry_1000	COG1902	pentaerythritol trinitrate reductase activity
Acry_1002	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Acry_1005	COG3119	arylsulfatase activity
Acry_1006	COG0583	DNA-binding transcription factor activity
Acry_1007	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Acry_1008	COG0527	aspartate kinase activity
Acry_1009	COG2070	2-Nitropropane dioxygenase
Acry_1011	COG1426	Protein conserved in bacteria
Acry_1012	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Acry_1013	COG0124	histidyl-tRNA synthetase
Acry_1014	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Acry_1015	COG2890	protein-(glutamine-N5) methyltransferase activity
Acry_1019	COG0728	peptidoglycan biosynthetic process
Acry_1020	COG0180	Tryptophanyl-tRNA synthetase
Acry_1032	COG1960	acyl-CoA dehydrogenase activity
Acry_1034	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Acry_1038	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Acry_1039	COG0506	proline dehydrogenase activity
Acry_1039	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Acry_1039	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Acry_1046	COG0129	dihydroxy-acid dehydratase activity
Acry_1047	COG0477	Major facilitator Superfamily
Acry_1048	COG0410	ABC transporter
Acry_1050	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_1051	COG0559	Belongs to the binding-protein-dependent transport system permease family
Acry_1053	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Acry_1054	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Acry_1055	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Acry_1058	COG1573	uracil-dna glycosylase
Acry_1062	COG1879	ABC-type sugar transport system periplasmic component
Acry_1063	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_1064	COG1129	ABC transporter
Acry_1066	COG2186	Transcriptional regulator
Acry_1067	COG1850	ribulose-bisphosphate carboxylase activity
Acry_1069	COG0287	Prephenate dehydrogenase
Acry_1071	COG1129	ABC transporter
Acry_1073	COG0431	NADPH-dependent FMN reductase
Acry_1076	COG0668	transmembrane transport
Acry_1081	COG0179	Fumarylacetoacetate (FAA) hydrolase
Acry_1088	COG2072	flavoprotein involved in K transport
Acry_1094	COG1845	cytochrome c oxidase, subunit III
Acry_1095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Acry_1096	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Acry_1099	COG0583	DNA-binding transcription factor activity
Acry_1100	COG2226	methyltransferase
Acry_1104	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Acry_1107	COG0517	IMP dehydrogenase activity
Acry_1107	COG0516	GMP reductase activity
Acry_1108	COG1007	ATP synthesis coupled electron transport
Acry_1111	COG0713	ATP synthesis coupled electron transport
Acry_1113	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Acry_1114	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Acry_1117	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Acry_1118	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Acry_1118	COG0649	NAD binding
Acry_1119	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Acry_1120	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Acry_1121	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Acry_1123	COG0673	inositol 2-dehydrogenase activity
Acry_1124	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Acry_1125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Acry_1129	COG0789	Transcriptional regulator
Acry_1132	COG2132	Multicopper oxidase
Acry_1134	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Acry_1134	COG2755	lipolytic protein G-D-S-L family
Acry_1136	COG0765	amino acid transport
Acry_1138	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_1139	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_1140	COG1129	ABC transporter
Acry_1142	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Acry_1147	COG0753	catalase activity
Acry_1148	COG0402	S-adenosylhomocysteine deaminase activity
Acry_1150	COG3195	allantoin biosynthetic process
Acry_1150	COG3648	Uricase
Acry_1152	COG2351	hydroxyisourate hydrolase activity
Acry_1156	COG0583	DNA-binding transcription factor activity
Acry_1157	COG3960	tartronate-semialdehyde synthase activity
Acry_1158	COG3622	Belongs to the hyi family
Acry_1159	COG2084	Dehydrogenase
Acry_1162	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Acry_1170	COG0582	viral genome integration into host DNA
Acry_1177	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Acry_1178	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Acry_1179	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Acry_1186	COG0601	transmembrane transport
Acry_1187	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Acry_1189	COG0811	peptide transport
Acry_1191	COG4974	Belongs to the 'phage' integrase family
Acry_1193	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Acry_1193	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Acry_1195	COG0318	PFAM AMP-dependent synthetase and ligase
Acry_1198	COG0142	geranyltranstransferase activity
Acry_1199	COG1722	exodeoxyribonuclease VII activity
Acry_1200	COG0123	including yeast histone deacetylase and acetoin utilization protein
Acry_1202	COG1940	carbohydrate kinase activity
Acry_1204	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Acry_1208	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Acry_1209	COG1381	Involved in DNA repair and RecF pathway recombination
Acry_1211	COG1473	amidohydrolase
Acry_1214	COG1088	dTDP-glucose 4,6-dehydratase activity
Acry_1215	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Acry_1216	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Acry_1217	COG1091	dTDP-4-dehydrorhamnose reductase activity
Acry_1222	COG0126	phosphoglycerate kinase activity
Acry_1223	COG0312	modulator of DNA gyrase
Acry_1224	COG1612	heme a metabolic process
Acry_1225	COG1612	heme a metabolic process
Acry_1226	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Acry_1228	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Acry_1231	COG0315	cyclic pyranopterin monophosphate synthase activity
Acry_1232	COG0134	indole-3-glycerol-phosphate synthase activity
Acry_1233	COG0512	Glutamine amidotransferase of anthranilate synthase
Acry_1233	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Acry_1234	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Acry_1236	COG0149	triose-phosphate isomerase activity
Acry_1237	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Acry_1238	COG0504	CTP synthase activity
Acry_1239	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Acry_1256	COG0318	PFAM AMP-dependent synthetase and ligase
Acry_1257	COG0183	Belongs to the thiolase family
Acry_1259	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_1260	COG1960	acyl-CoA dehydrogenase activity
Acry_1262	COG3239	Fatty acid desaturase
Acry_1269	COG2271	Major facilitator Superfamily
Acry_1270	COG0473	3-isopropylmalate dehydrogenase activity
Acry_1271	COG3387	PFAM Glycoside hydrolase 15-related
Acry_1272	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Acry_1273	COG0363	glucosamine-6-phosphate deaminase activity
Acry_1275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Acry_1276	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Acry_1277	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Acry_1278	COG0481	GTPase activity
Acry_1280	COG0582	viral genome integration into host DNA
Acry_1283	COG2259	Doxx family
Acry_1284	COG0583	DNA-binding transcription factor activity
Acry_1296	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Acry_1296	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Acry_1297	COG1494	fructose-1,6-bisphosphatase
Acry_1299	COG0436	Aminotransferase
Acry_1301	COG3243	poly(R)-hydroxyalkanoic acid synthase
Acry_1302	COG0438	transferase activity, transferring glycosyl groups
Acry_1304	COG0523	cobalamin synthesis protein
Acry_1306	COG0656	L-ascorbic acid biosynthetic process
Acry_1309	COG2223	nitrite transmembrane transporter activity
Acry_1310	COG0488	(ABC) transporter
Acry_1311	COG0105	UTP biosynthetic process
Acry_1315	COG1846	Transcriptional regulator
Acry_1318	COG0175	sulfate reduction
Acry_1320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Acry_1325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Acry_1326	COG0400	carboxylic ester hydrolase activity
Acry_1328	COG0133	tryptophan synthase activity
Acry_1329	COG0159	tryptophan synthase activity
Acry_1331	COG1570	exodeoxyribonuclease VII activity
Acry_1337	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Acry_1337	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Acry_1339	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Acry_1340	COG0343	queuine tRNA-ribosyltransferase activity
Acry_1341	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Acry_1342	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Acry_1343	COG1970	mechanosensitive ion channel activity
Acry_1346	COG1380	Effector of murein hydrolase LrgA
Acry_1347	COG0583	DNA-binding transcription factor activity
Acry_1348	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Acry_1349	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Acry_1351	COG3754	Rhamnan synthesis protein F
Acry_1353	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Acry_1355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Acry_1362	COG1132	(ABC) transporter
Acry_1368	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Acry_1369	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Acry_1376	COG0459	protein refolding
Acry_1380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Acry_1381	COG3350	monooxygenase activity
Acry_1387	COG0346	lactoylglutathione lyase activity
Acry_1389	COG3118	belongs to the thioredoxin family
Acry_1390	COG0446	pyridine nucleotide-disulphide oxidoreductase
Acry_1396	COG0651	ATP synthesis coupled electron transport
Acry_1397	COG0650	Formate hydrogenlyase subunit 4
Acry_1399	COG0651	ATP synthesis coupled electron transport
Acry_1401	COG3260	NADH ubiquinone oxidoreductase 20
Acry_1404	COG0215	cysteine-tRNA ligase activity
Acry_1405	COG1914	H( )-stimulated, divalent metal cation uptake system
Acry_1406	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Acry_1407	COG0154	amidase activity
Acry_1409	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Acry_1410	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Acry_1412	COG0477	Major facilitator Superfamily
Acry_1413	COG0131	Imidazoleglycerol-phosphate dehydratase
Acry_1414	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Acry_1416	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Acry_1417	COG0107	imidazoleglycerol-phosphate synthase activity
Acry_1418	COG0140	phosphoribosyl-ATP diphosphatase activity
Acry_1419	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Acry_1421	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Acry_1424	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_1427	COG2902	Dehydrogenase
Acry_1430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Acry_1432	COG0142	geranyltranstransferase activity
Acry_1434	COG2264	protein methyltransferase activity
Acry_1436	COG0427	acetyl-CoA hydrolase
Acry_1437	COG0592	DNA-directed DNA polymerase activity
Acry_1438	COG4176	ABC-type proline glycine betaine transport system permease component
Acry_1439	COG1116	anion transmembrane transporter activity
Acry_1440	COG0114	fumarate hydratase activity
Acry_1443	COG3384	dioxygenase
Acry_1447	COG0194	GDP metabolic process
Acry_1448	COG1561	YicC-like family, N-terminal region
Acry_1449	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Acry_1450	COG1024	Enoyl-CoA hydratase
Acry_1452	COG0492	ferredoxin-NADP+ reductase activity
Acry_1453	COG0802	atpase or kinase
Acry_1455	COG1074	ATP-dependent DNA helicase activity
Acry_1457	COG1607	acyl-coa hydrolase
Acry_1458	COG2814	Major facilitator Superfamily
Acry_1459	COG0667	Aldo Keto reductase
Acry_1460	COG0811	peptide transport
Acry_1461	COG0848	biopolymer transport protein
Acry_1463	COG1692	metallophosphoesterase
Acry_1464	COG3038	cytochrome b561
Acry_1467	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Acry_1468	COG4974	Belongs to the 'phage' integrase family
Acry_1471	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Acry_1472	COG2204	response regulator
Acry_1473	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Acry_1474	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Acry_1476	COG0590	tRNA wobble adenosine to inosine editing
Acry_1477	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Acry_1478	COG1187	pseudouridine synthase activity
Acry_1479	COG0742	ribosomal rna small subunit methyltransferase
Acry_1481	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Acry_1483	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Acry_1484	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Acry_1487	COG0668	transmembrane transport
Acry_1491	COG2814	Major facilitator Superfamily
Acry_1492	COG0024	Methionine aminopeptidase
Acry_1493	COG2003	Belongs to the UPF0758 family
Acry_1496	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Acry_1500	COG1396	sequence-specific DNA binding
Acry_1500	COG3800	Transcriptional regulator
Acry_1501	COG2224	Isocitrate lyase
Acry_1504	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Acry_1504	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Acry_1507	COG0717	Belongs to the dCTP deaminase family
Acry_1508	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Acry_1509	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Acry_1510	COG0359	binds to the 23S rRNA
Acry_1511	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Acry_1512	COG0360	Binds together with S18 to 16S ribosomal RNA
Acry_1516	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Acry_1525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Acry_1527	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Acry_1528	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Acry_1530	COG2171	N-acyltransferase activity
Acry_1531	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Acry_1533	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Acry_1535	COG5002	protein histidine kinase activity
Acry_1536	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Acry_1537	COG2096	Adenosyltransferase
Acry_1539	COG0300	oxidoreductase activity
Acry_1541	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Acry_1542	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Acry_1546	COG1058	Belongs to the CinA family
Acry_1546	COG1546	Belongs to the CinA family
Acry_1547	COG0494	nUDIX hydrolase
Acry_1548	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Acry_1551	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Acry_1552	COG5001	Diguanylate cyclase
Acry_1553	COG3300	MHYT domain
Acry_1553	COG5001	Diguanylate cyclase
Acry_1556	COG1960	acyl-CoA dehydrogenase activity
Acry_1558	COG5285	phytanoyl-CoA dioxygenase
Acry_1560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Acry_1567	COG0275	rRNA processing
Acry_1573	COG1960	acyl-CoA dehydrogenase activity
Acry_1576	COG0183	Belongs to the thiolase family
Acry_1578	COG0667	Aldo Keto reductase
Acry_1581	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Acry_1582	COG1140	nitrate reductase beta subunit
Acry_1583	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Acry_1584	COG2181	nitrate reductase activity
Acry_1588	COG0840	transmembrane signaling receptor activity
Acry_1590	COG1063	alcohol dehydrogenase
Acry_1591	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_1592	COG2084	Dehydrogenase
Acry_1593	COG1129	ABC transporter
Acry_1597	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Acry_1598	COG0477	Major facilitator Superfamily
Acry_1599	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Acry_1601	COG1879	ABC-type sugar transport system periplasmic component
Acry_1602	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_1604	COG2199	diguanylate cyclase activity
Acry_1605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Acry_1610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Acry_1611	COG1793	dna ligase
Acry_1613	COG1201	RNA secondary structure unwinding
Acry_1615	COG0415	Belongs to the DNA photolyase family
Acry_1618	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Acry_1619	COG2211	Major facilitator Superfamily
Acry_1621	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Acry_1622	COG0508	dehydrogenase complex catalyzes the overall conversion of
Acry_1625	COG0045	succinate-CoA ligase (ADP-forming) activity
Acry_1626	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Acry_1628	COG0405	Gamma-glutamyltransferase
Acry_1629	COG0436	Aminotransferase
Acry_1630	COG0516	GMP reductase activity
Acry_1630	COG0517	IMP dehydrogenase activity
Acry_1631	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Acry_1634	COG1294	oxidase, subunit
Acry_1635	COG1271	oxidase subunit
Acry_1636	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Acry_1637	COG4988	ABC transporter
Acry_1641	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_1645	COG0484	heat shock protein binding
Acry_1646	COG0443	Heat shock 70 kDa protein
Acry_1647	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Acry_1649	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_1652	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Acry_1653	COG0328	RNA-DNA hybrid ribonuclease activity
Acry_1654	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_1657	COG1175	transmembrane transport
Acry_1659	COG1063	alcohol dehydrogenase
Acry_1660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Acry_1663	COG1420	regulation of RNA biosynthetic process
Acry_1664	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Acry_1665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Acry_1670	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Acry_1670	COG0517	IMP dehydrogenase activity
Acry_1673	COG1137	ATPase activity
Acry_1674	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Acry_1675	COG0193	aminoacyl-tRNA hydrolase activity
Acry_1676	COG0012	GTP binding
Acry_1678	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Acry_1679	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Acry_1680	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Acry_1681	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Acry_1682	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Acry_1685	COG1657	PFAM Prenyltransferase squalene oxidase
Acry_1686	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Acry_1687	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Acry_1689	COG2301	Belongs to the HpcH HpaI aldolase family
Acry_1690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Acry_1692	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_1693	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Acry_1694	COG0052	Belongs to the universal ribosomal protein uS2 family
Acry_1695	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Acry_1700	COG1410	methionine synthase
Acry_1700	COG0646	methionine synthase
Acry_1701	COG0697	spore germination
Acry_1706	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Acry_1707	COG0483	inositol monophosphate 1-phosphatase activity
Acry_1715	COG1024	Enoyl-CoA hydratase
Acry_1717	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Acry_1718	COG0746	molybdenum cofactor guanylyltransferase activity
Acry_1719	COG2095	MarC family integral membrane protein
Acry_1720	COG0776	regulation of translation
Acry_1721	COG0284	orotidine-5'-phosphate decarboxylase activity
Acry_1722	COG0135	phosphoribosylanthranilate isomerase activity
Acry_1723	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Acry_1724	COG2226	methyltransferase
Acry_1725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Acry_1726	COG0756	dUTP diphosphatase activity
Acry_1727	COG4221	oxidoreductase activity
Acry_1728	COG3046	protein related to deoxyribodipyrimidine photolyase
Acry_1733	COG1902	pentaerythritol trinitrate reductase activity
Acry_1734	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_1738	COG2197	response regulator
Acry_1739	COG2010	Cytochrome c
Acry_1743	COG1012	belongs to the aldehyde dehydrogenase family
Acry_1744	COG3284	Transcriptional regulator
Acry_1746	COG1228	amidohydrolase
Acry_1747	COG2986	histidine ammonia-lyase
Acry_1749	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Acry_1750	COG2188	Transcriptional regulator
Acry_1752	COG0393	Putative heavy-metal-binding
Acry_1754	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Acry_1756	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Acry_1757	COG1051	belongs to the nudix hydrolase family
Acry_1758	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Acry_1759	COG3956	TIGRFAM MazG family protein
Acry_1760	COG0483	inositol monophosphate 1-phosphatase activity
Acry_1761	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Acry_1762	COG1923	regulation of RNA biosynthetic process
Acry_1764	COG0482	sulfurtransferase activity
Acry_1767	COG1045	serine acetyltransferase
Acry_1768	COG2945	thiolester hydrolase activity
Acry_1769	COG1349	DNA-binding transcription factor activity
Acry_1774	COG0778	Nitroreductase
Acry_1775	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Acry_1777	COG2226	methyltransferase
Acry_1778	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Acry_1780	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Acry_1783	COG0525	valine-tRNA ligase activity
Acry_1785	COG0312	modulator of DNA gyrase
Acry_1786	COG0612	Peptidase, M16
Acry_1788	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Acry_1789	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Acry_1790	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Acry_1795	COG1131	(ABC) transporter
Acry_1796	COG0842	Transport permease protein
Acry_1797	COG0842	Transport permease protein
Acry_1798	COG1151	hydroxylamine reductase activity
Acry_1799	COG0633	Ferredoxin
Acry_1799	COG0543	2 iron, 2 sulfur cluster binding
Acry_1800	COG1959	2 iron, 2 sulfur cluster binding
Acry_1803	COG0438	transferase activity, transferring glycosyl groups
Acry_1808	COG1518	maintenance of DNA repeat elements
Acry_1811	COG1857	crispr-associated protein
Acry_1814	COG1203	CRISPR-associated helicase, Cas3
Acry_1816	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Acry_1823	COG0542	response to heat
Acry_1825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Acry_1826	COG1763	Mo-molybdopterin cofactor biosynthetic process
Acry_1829	COG0314	molybdopterin synthase activity
Acry_1830	COG0745	RESPONSE REGULATOR receiver
Acry_1832	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Acry_1833	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Acry_1836	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Acry_1837	COG3394	polysaccharide catabolic process
Acry_1844	COG0513	Belongs to the DEAD box helicase family
Acry_1845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Acry_1848	COG3485	protocatechuate 3,4-dioxygenase
Acry_1849	COG3485	protocatechuate 3,4-dioxygenase
Acry_1851	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Acry_1852	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_1854	COG1129	ABC transporter
Acry_1855	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_1856	COG3618	amidohydrolase
Acry_1857	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Acry_1858	COG1312	Catalyzes the dehydration of D-mannonate
Acry_1862	COG2721	sulfolactate sulfo-lyase activity
Acry_1865	COG0559	Belongs to the binding-protein-dependent transport system permease family
Acry_1867	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Acry_1868	COG0156	8-amino-7-oxononanoate synthase activity
Acry_1869	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Acry_1870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Acry_1874	COG3038	cytochrome b561
Acry_1878	COG2264	protein methyltransferase activity
Acry_1879	COG2009	succinate dehydrogenase
Acry_1881	COG1053	succinate dehydrogenase
Acry_1883	COG2205	protein histidine kinase activity
Acry_1884	COG0745	RESPONSE REGULATOR receiver
Acry_1886	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Acry_1887	COG1473	amidohydrolase
Acry_1889	COG1846	Transcriptional regulator
Acry_1890	COG1566	PFAM secretion protein HlyD family protein
Acry_1891	COG2814	Major facilitator Superfamily
Acry_1892	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Acry_1900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Acry_1901	COG1360	Flagellar Motor Protein
Acry_1904	COG0463	Glycosyl transferase, family 2
Acry_1907	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Acry_1908	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Acry_1909	COG0741	lytic transglycosylase activity
Acry_1910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Acry_1911	COG1058	Belongs to the CinA family
Acry_1911	COG1546	Belongs to the CinA family
Acry_1921	COG0203	ribosomal protein L17
Acry_1922	COG0202	RNA polymerase activity
Acry_1923	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Acry_1924	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Acry_1925	COG0563	adenylate kinase activity
Acry_1927	COG0200	Binds to the 23S rRNA
Acry_1928	COG1841	ribosomal large subunit assembly
Acry_1929	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Acry_1930	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Acry_1931	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Acry_1932	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Acry_1933	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Acry_1934	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Acry_1935	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Acry_1936	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Acry_1937	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Acry_1938	COG0255	Belongs to the universal ribosomal protein uL29 family
Acry_1939	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Acry_1940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Acry_1941	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Acry_1942	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Acry_1943	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Acry_1944	COG0089	rRNA binding
Acry_1945	COG0088	Forms part of the polypeptide exit tunnel
Acry_1946	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Acry_1947	COG0051	transcription antitermination factor activity, RNA binding
Acry_1948	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Acry_1949	COG0049	tRNA binding
Acry_1950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Acry_1951	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Acry_1952	COG0085	RNA polymerase activity
Acry_1953	COG0222	ribosome binding
Acry_1954	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Acry_1955	COG0081	regulation of translation
Acry_1956	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Acry_1957	COG3047	cAMP biosynthetic process
Acry_1958	COG0667	Aldo Keto reductase
Acry_1959	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Acry_1960	COG0647	UMP catabolic process
Acry_1963	COG0179	Fumarylacetoacetate (FAA) hydrolase
Acry_1971	COG4214	carbohydrate transport
Acry_1973	COG4213	ABC transporter substrate-binding protein
Acry_1975	COG5265	(ABC) transporter
Acry_1982	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Acry_1988	COG0776	regulation of translation
Acry_1990	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Acry_1998	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Acry_1999	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Acry_2001	COG2816	NAD+ diphosphatase activity
Acry_2002	COG0655	NAD(P)H dehydrogenase (quinone) activity
Acry_2007	COG0714	Associated with various cellular activities
Acry_2009	COG0494	nUDIX hydrolase
Acry_2010	COG0617	tRNA 3'-terminal CCA addition
Acry_2011	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Acry_2012	COG0248	Ppx GppA phosphatase
Acry_2014	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Acry_2015	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Acry_2022	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Acry_2027	COG0860	N-Acetylmuramoyl-L-alanine amidase
Acry_2029	COG0473	3-isopropylmalate dehydrogenase activity
Acry_2031	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Acry_2031	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Acry_2036	COG2204	response regulator
Acry_2038	COG0629	single-stranded DNA binding
Acry_2039	COG1294	oxidase, subunit
Acry_2040	COG1271	oxidase subunit
Acry_2042	COG3781	membrane
Acry_2044	COG0243	molybdopterin cofactor binding
Acry_2050	COG0495	leucyl-tRNA aminoacylation
Acry_2055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Acry_2056	COG2733	membrane
Acry_2059	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Acry_2063	COG1752	Esterase of the alpha-beta hydrolase superfamily
Acry_2065	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Acry_2068	COG2271	Major facilitator Superfamily
Acry_2072	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Acry_2073	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Acry_2076	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Acry_2077	COG0601	transmembrane transport
Acry_2082	COG1280	lysine exporter protein (LysE YggA)
Acry_2084	COG3008	intermembrane lipid transfer
Acry_2094	COG3501	Rhs element vgr protein
Acry_2098	COG0515	serine threonine protein kinase
Acry_2101	COG0514	ATP-dependent DNA helicase (RecQ)
Acry_2104	COG0308	aminopeptidase N
Acry_2109	COG0531	amino acid
Acry_2111	COG0625	glutathione transferase activity
Acry_2116	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Acry_2117	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Acry_2118	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Acry_2119	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Acry_2119	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Acry_2121	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Acry_2121	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Acry_2122	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Acry_2123	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Acry_2124	COG0698	ribose 5-phosphate isomerase
Acry_2125	COG2835	tetraacyldisaccharide 4'-kinase activity
Acry_2129	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Acry_2130	COG1684	flagellar biosynthetic protein fliR
Acry_2131	COG1987	bacterial-type flagellum assembly
Acry_2132	COG1677	Flagellar hook-basal body complex protein FliE
Acry_2133	COG1558	bacterial-type flagellum-dependent cell motility
Acry_2135	COG1338	Plays a role in the flagellum-specific transport system
Acry_2136	COG5000	phosphorelay sensor kinase activity
Acry_2138	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Acry_2139	COG0594	ribonuclease P activity
Acry_2140	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Acry_2141	COG0706	membrane insertase activity
Acry_2142	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Acry_2143	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Acry_2144	COG0840	transmembrane signaling receptor activity
Acry_2145	COG1253	flavin adenine dinucleotide binding
Acry_2147	COG0473	3-isopropylmalate dehydrogenase activity
Acry_2148	COG0066	3-isopropylmalate dehydratase activity
Acry_2149	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Acry_2150	COG0335	large ribosomal subunit rRNA binding
Acry_2151	COG0336	Belongs to the RNA methyltransferase TrmD family
Acry_2152	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Acry_2153	COG0228	four-way junction DNA binding
Acry_2154	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Acry_2155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Acry_2156	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Acry_2157	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Acry_2158	COG0740	serine-type endopeptidase activity
Acry_2161	COG1802	Transcriptional regulator
Acry_2165	COG0109	protoheme IX farnesyltransferase activity
Acry_2166	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Acry_2167	COG1565	acr, cog1565
Acry_2167	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Acry_2177	COG0477	Major facilitator Superfamily
Acry_2184	COG0574	Belongs to the PEP-utilizing enzyme family
Acry_2184	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Acry_2185	COG0751	glycine-tRNA ligase activity
Acry_2186	COG0752	glycyl-tRNA synthetase alpha subunit
Acry_2188	COG1960	acyl-CoA dehydrogenase activity
Acry_2189	COG0825	malonyl-CoA metabolic process
Acry_2192	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Acry_2195	COG0859	PFAM glycosyl transferase family 9
Acry_2196	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Acry_2199	COG1414	Transcriptional regulator
Acry_2201	COG0410	ABC transporter
Acry_2204	COG0559	Belongs to the binding-protein-dependent transport system permease family
Acry_2208	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Acry_2215	COG1129	ABC transporter
Acry_2216	COG1879	ABC-type sugar transport system periplasmic component
Acry_2218	COG1695	Transcriptional regulator
Acry_2228	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Acry_2229	COG1473	amidohydrolase
Acry_2231	COG0583	DNA-binding transcription factor activity
Acry_2232	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_2234	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Acry_2238	COG1129	ABC transporter
Acry_2239	COG1879	ABC-type sugar transport system periplasmic component
Acry_2240	COG1414	Transcriptional regulator
Acry_2242	COG1802	Transcriptional regulator
Acry_2243	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Acry_2244	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Acry_2245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Acry_2246	COG0653	protein targeting
Acry_2248	COG1846	Transcriptional regulator
Acry_2249	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Acry_2250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Acry_2252	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Acry_2253	COG0730	response to heat
Acry_2256	COG0183	Belongs to the thiolase family
Acry_2259	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Acry_2261	COG0792	nuclease activity
Acry_2263	COG2897	thiosulfate sulfurtransferase activity
Acry_2265	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Acry_2266	COG0316	Belongs to the HesB IscA family
Acry_2267	COG2151	metal-sulfur cluster biosynthetic enzyme
Acry_2269	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Acry_2270	COG0719	Fe-S assembly protein
Acry_2271	COG0396	ATPase activity
Acry_2272	COG0719	Fe-S assembly protein
Acry_2275	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Acry_2276	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Acry_2280	COG1719	4-vinyl reductase, 4VR
Acry_2286	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Acry_2288	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Acry_2289	COG0280	phosphate acetyltransferase
Acry_2289	COG0281	malic enzyme
Acry_2290	COG0321	lipoyl(octanoyl) transferase activity
Acry_2302	COG1484	DNA-dependent DNA replication
Acry_2303	COG4584	PFAM Integrase catalytic
Acry_2309	COG0582	viral genome integration into host DNA
Acry_2310	COG0582	viral genome integration into host DNA
Acry_2313	COG3718	enzyme involved in inositol metabolism
Acry_2314	COG3962	Belongs to the TPP enzyme family
Acry_2320	COG0673	inositol 2-dehydrogenase activity
Acry_2321	COG1082	Xylose isomerase domain protein TIM barrel
Acry_2324	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_2329	COG0673	inositol 2-dehydrogenase activity
Acry_2330	COG0673	inositol 2-dehydrogenase activity
Acry_2332	COG3002	Belongs to the UPF0753 family
Acry_2333	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Acry_2336	COG1595	DNA-templated transcription, initiation
Acry_2343	COG0415	Belongs to the DNA photolyase family
Acry_2348	COG4974	Belongs to the 'phage' integrase family
Acry_2349	COG0517	IMP dehydrogenase activity
Acry_2354	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Acry_2355	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_2360	COG0735	belongs to the Fur family
Acry_2361	COG0318	PFAM AMP-dependent synthetase and ligase
Acry_2363	COG0604	alcohol dehydrogenase
Acry_2364	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Acry_2365	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Acry_2366	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Acry_2368	COG1121	(ABC) transporter
Acry_2376	COG1509	lysine 2,3-aminomutase activity
Acry_2378	COG0511	ligase activity, forming carbon-carbon bonds
Acry_2379	COG0439	Biotin carboxylase
Acry_2381	COG5001	Diguanylate cyclase
Acry_2381	COG3300	MHYT domain
Acry_2382	COG0243	molybdopterin cofactor binding
Acry_2383	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Acry_2384	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Acry_2387	COG0840	transmembrane signaling receptor activity
Acry_2388	COG0625	glutathione transferase activity
Acry_2389	COG1012	belongs to the aldehyde dehydrogenase family
Acry_2390	COG1012	belongs to the aldehyde dehydrogenase family
Acry_2395	COG3706	GGDEF domain
Acry_2396	COG0587	DNA-directed DNA polymerase activity
Acry_2397	COG0183	Belongs to the thiolase family
Acry_2398	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_2399	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Acry_2401	COG2226	methyltransferase
Acry_2403	COG1475	DNA binding
Acry_2404	COG1192	Involved in chromosome partitioning
Acry_2405	COG0357	Ribosomal RNA small subunit methyltransferase G
Acry_2406	COG0445	tRNA wobble uridine modification
Acry_2407	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Acry_2409	COG1331	Highly conserved protein containing a thioredoxin domain
Acry_2410	COG0489	protein tyrosine kinase activity
Acry_2413	COG2081	HI0933 family
Acry_2415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Acry_2416	COG2076	Multidrug Resistance protein
Acry_2428	COG0582	viral genome integration into host DNA
Acry_2429	COG3395	kinase activity
Acry_2430	COG3622	Belongs to the hyi family
Acry_2431	COG2084	Dehydrogenase
Acry_2432	COG1609	Transcriptional regulator
Acry_2433	COG2084	Dehydrogenase
Acry_2434	COG0235	Class ii aldolase
Acry_2437	COG0477	Major facilitator Superfamily
Acry_2439	COG3180	Ammonia monooxygenase
Acry_2440	COG0583	DNA-binding transcription factor activity
Acry_2441	COG0492	ferredoxin-NADP+ reductase activity
Acry_2442	COG1522	sequence-specific DNA binding
Acry_2444	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Acry_2446	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Acry_2447	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Acry_2449	COG3494	Protein of unknown function (DUF1009)
Acry_2450	COG0346	lactoylglutathione lyase activity
Acry_2451	COG0457	Tetratricopeptide repeat
Acry_2460	COG0488	(ABC) transporter
Acry_2462	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Acry_2463	COG0318	PFAM AMP-dependent synthetase and ligase
Acry_2465	COG2608	mercury ion transmembrane transporter activity
Acry_2466	COG2217	Heavy metal translocating P-type atpase
Acry_2467	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_2469	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Acry_2470	COG0129	dihydroxy-acid dehydratase activity
Acry_2474	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Acry_2475	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Acry_2476	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Acry_2477	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Acry_2481	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Acry_2484	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Acry_2488	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Acry_2489	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Acry_2490	COG0586	Pfam SNARE associated Golgi protein
Acry_2493	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Acry_2496	COG0552	protein localization to endoplasmic reticulum
Acry_2497	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Acry_2498	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Acry_2500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Acry_2502	COG2814	Major facilitator Superfamily
Acry_2503	COG0459	protein refolding
Acry_2504	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Acry_2505	COG5425	PFAM Usg family protein
Acry_2534	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Acry_2537	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Acry_2538	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Acry_2540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Acry_2541	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Acry_2542	COG0248	Ppx GppA phosphatase
Acry_2548	COG0247	lactate metabolic process
Acry_2549	COG0277	FAD linked oxidase domain protein
Acry_2550	COG0277	FAD linked oxidase domain protein
Acry_2551	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Acry_2552	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Acry_2553	COG0528	UMP kinase activity
Acry_2554	COG0233	cytoplasmic translational termination
Acry_2555	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Acry_2556	COG0575	Belongs to the CDS family
Acry_2557	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Acry_2558	COG0750	zinc metalloprotease
Acry_2559	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Acry_2561	COG0586	Pfam SNARE associated Golgi protein
Acry_2564	COG1070	Carbohydrate kinase
Acry_2566	COG1653	transport
Acry_2568	COG3833	ABC-type maltose transport systems, permease component
Acry_2572	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Acry_2573	COG0235	Class ii aldolase
Acry_2576	COG2860	membrane
Acry_2579	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
Acry_2581	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_2590	COG0840	transmembrane signaling receptor activity
Acry_2591	COG3386	PFAM SMP-30 Gluconolaconase
Acry_2592	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_2593	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_2594	COG1129	ABC transporter
Acry_2596	COG3386	PFAM SMP-30 Gluconolaconase
Acry_2597	COG0800	Aldolase
Acry_2598	COG3734	2-keto-3-deoxy-galactonokinase
Acry_2601	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_2603	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_2608	COG3396	Phenylacetate-CoA oxygenase
Acry_2609	COG3460	Phenylacetate-CoA oxygenase
Acry_2610	COG3396	Phenylacetate-CoA oxygenase
Acry_2611	COG2151	metal-sulfur cluster biosynthetic enzyme
Acry_2612	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Acry_2616	COG2376	Dihydroxyacetone kinase
Acry_2617	COG1461	Dihydroxyacetone kinase
Acry_2620	COG0606	chelatase, subunit chli
Acry_2621	COG2003	Belongs to the UPF0758 family
Acry_2622	COG0251	oxidation-reduction process
Acry_2624	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Acry_2625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Acry_2629	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Acry_2630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Acry_2631	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Acry_2632	COG0071	Belongs to the small heat shock protein (HSP20) family
Acry_2633	COG0254	rRNA binding
Acry_2635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Acry_2639	COG0513	Belongs to the DEAD box helicase family
Acry_2640	COG3284	Transcriptional regulator
Acry_2644	COG3302	dmso reductase anchor subunit
Acry_2645	COG0437	4 iron, 4 sulfur cluster binding
Acry_2646	COG0243	molybdopterin cofactor binding
Acry_2647	COG0076	glutamate decarboxylase activity
Acry_2650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Acry_2654	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Acry_2654	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Acry_2656	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Acry_2659	COG0667	Aldo Keto reductase
Acry_2660	COG0302	gtp cyclohydrolase
Acry_2661	COG2967	ApaG domain
Acry_2663	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Acry_2664	COG0047	phosphoribosylformylglycinamidine synthase activity
Acry_2665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Acry_2666	COG0271	Belongs to the BolA IbaG family
Acry_2667	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Acry_2669	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Acry_2671	COG2095	MarC family integral membrane protein
Acry_2675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Acry_2676	COG2223	nitrite transmembrane transporter activity
Acry_2677	COG1321	iron dependent repressor
Acry_2679	COG0628	permease
Acry_2680	COG1254	Belongs to the acylphosphatase family
Acry_2686	COG1183	phosphatidylcholine synthase activity
Acry_2687	COG0688	phosphatidylethanolamine metabolic process
Acry_2690	COG1530	ribonuclease E activity
Acry_2691	COG0424	maF-like protein
Acry_2692	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Acry_2693	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Acry_2695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Acry_2696	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Acry_2697	COG2084	Dehydrogenase
Acry_2700	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Acry_2702	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Acry_2705	COG0840	transmembrane signaling receptor activity
Acry_2707	COG0745	RESPONSE REGULATOR receiver
Acry_2708	COG2198	Histidine kinase
Acry_2708	COG0643	Histidine kinase
Acry_2709	COG0835	chemotaxis
Acry_2710	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Acry_2711	COG2201	protein-glutamate methylesterase activity
Acry_2712	COG0745	RESPONSE REGULATOR receiver
Acry_2713	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Acry_2718	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Acry_2719	COG0564	pseudouridine synthase activity
Acry_2728	COG3665	Urea carboxylase-associated protein
Acry_2740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Acry_2741	COG0583	DNA-binding transcription factor activity
Acry_2747	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Acry_2748	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Acry_2749	COG0405	Gamma-glutamyltransferase
Acry_2751	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Acry_2757	COG0602	queuosine metabolic process
Acry_2760	COG0237	dephospho-CoA kinase activity
Acry_2761	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Acry_2765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Acry_2767	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Acry_2776	COG0667	Aldo Keto reductase
Acry_2777	COG0583	DNA-binding transcription factor activity
Acry_2778	COG3246	L-lysine catabolic process to acetate
Acry_2779	COG1250	3-hydroxyacyl-CoA dehydrogenase
Acry_2781	COG1129	ABC transporter
Acry_2783	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_2784	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Acry_2785	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Acry_2786	COG1696	Membrane protein involved in D-alanine export
Acry_2789	COG3284	Transcriptional regulator
Acry_2793	COG3791	Glutathione-dependent formaldehyde-activating
Acry_2794	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Acry_2795	COG4772	TonB-dependent receptor
Acry_2796	COG0277	FAD linked oxidase domain protein
Acry_2797	COG4993	Dehydrogenase
Acry_2797	COG2010	Cytochrome c
Acry_2799	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Acry_2800	COG0175	sulfate reduction
Acry_2801	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Acry_2803	COG1648	precorrin-2 dehydrogenase activity
Acry_2803	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Acry_2804	COG1522	sequence-specific DNA binding
Acry_2805	COG0521	Mo-molybdopterin cofactor biosynthetic process
Acry_2810	COG2200	EAL domain
Acry_2810	COG2199	diguanylate cyclase activity
Acry_2810	COG2203	Gaf domain
Acry_2813	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Acry_2814	COG0745	RESPONSE REGULATOR receiver
Acry_2819	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Acry_2820	COG0022	dehydrogenase e1 component
Acry_2820	COG0508	dehydrogenase complex catalyzes the overall conversion of
Acry_2821	COG0508	dehydrogenase complex catalyzes the overall conversion of
Acry_2823	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Acry_2824	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Acry_2825	COG2867	negative regulation of translational initiation
Acry_2829	COG0667	Aldo Keto reductase
Acry_2833	COG0028	Belongs to the TPP enzyme family
Acry_2834	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Acry_2836	COG1832	CoA-binding protein
Acry_2838	COG1686	Belongs to the peptidase S11 family
Acry_2842	COG1278	Cold shock
Acry_2844	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Acry_2848	COG2264	protein methyltransferase activity
Acry_2849	COG0596	Alpha beta hydrolase
Acry_2852	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Acry_2853	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Acry_2854	COG1138	Cytochrome C-type biogenesis protein
Acry_2855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Acry_2856	COG3088	subunit of a heme lyase
Acry_2858	COG5508	conserved small protein
Acry_2860	COG0028	Belongs to the TPP enzyme family
Acry_2863	COG1643	Atp-dependent helicase
Acry_2865	COG2863	cytochrome
Acry_2869	COG1127	ABC transporter
Acry_2870	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Acry_2871	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Acry_2873	COG0305	Participates in initiation and elongation during chromosome replication
Acry_2877	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Acry_2878	COG0004	ammonium transporteR
Acry_2880	COG0516	GMP reductase activity
Acry_2880	COG0517	IMP dehydrogenase activity
Acry_2881	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Acry_2882	COG1902	pentaerythritol trinitrate reductase activity
Acry_2883	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Acry_2885	COG3023	N-Acetylmuramoyl-L-alanine amidase
Acry_2886	COG0187	DNA topoisomerase II activity
Acry_2888	COG0583	DNA-binding transcription factor activity
Acry_2889	COG0679	Auxin Efflux Carrier
Acry_2890	COG2200	EAL domain
Acry_2897	COG1139	Iron-sulfur cluster binding protein
Acry_2899	COG0823	Involved in the tonB-independent uptake of proteins
Acry_2901	COG0848	biopolymer transport protein
Acry_2902	COG0811	peptide transport
Acry_2903	COG0824	Thioesterase
Acry_2904	COG2255	four-way junction helicase activity
Acry_2905	COG0632	four-way junction helicase activity
Acry_2906	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Acry_2907	COG0217	transcriptional regulatory protein
Acry_2909	COG0438	transferase activity, transferring glycosyl groups
Acry_2911	COG3624	Phosphonate C-P lyase system protein PhnG
Acry_2913	COG3626	phosphonate metabolism
Acry_2914	COG3627	carbon phosphorus lyase activity
Acry_2915	COG4107	phosphonate C-P lyase system protein PhnK
Acry_2916	COG4778	phosphonate C-P lyase system protein PhnL
Acry_2917	COG3454	Phosphonate metabolism
Acry_2919	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Acry_2920	COG2188	Transcriptional regulator
Acry_2921	COG1216	Glycosyl transferase, family 2
Acry_2921	COG0438	transferase activity, transferring glycosyl groups
Acry_2922	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Acry_2923	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Acry_2924	COG0438	transferase activity, transferring glycosyl groups
Acry_2924	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Acry_2927	COG2130	NADP-dependent
Acry_2931	COG0559	Belongs to the binding-protein-dependent transport system permease family
Acry_2934	COG0366	Alpha amylase catalytic
Acry_2935	COG0366	Alpha amylase catalytic
Acry_2936	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Acry_2944	COG0408	coproporphyrinogen oxidase activity
Acry_2947	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Acry_2948	COG0450	alkyl hydroperoxide reductase
Acry_2949	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Acry_2950	COG0704	Plays a role in the regulation of phosphate uptake
Acry_2951	COG0745	RESPONSE REGULATOR receiver
Acry_2953	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Acry_2956	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Acry_2958	COG2204	response regulator
Acry_2967	COG3267	Type II secretory pathway component ExeA
Acry_2967	COG3409	Peptidoglycan-binding domain 1 protein
Acry_2975	COG3284	Transcriptional regulator
Acry_2976	COG1063	alcohol dehydrogenase
Acry_2981	COG3254	rhamnose metabolic process
Acry_2982	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_2983	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_2987	COG4952	isomerase
Acry_2988	COG3347	Dehydrogenase
Acry_2988	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_2989	COG1070	Carbohydrate kinase
Acry_2990	COG0840	transmembrane signaling receptor activity
Acry_2990	COG0840	transmembrane signaling receptor activity
Acry_2992	COG0484	heat shock protein binding
Acry_2994	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Acry_2995	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
Acry_3001	COG0395	ABC-type sugar transport system, permease component
Acry_3003	COG1653	transport
Acry_3004	COG2267	carboxylic ester hydrolase activity
Acry_3005	COG2010	Cytochrome c
Acry_3005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Acry_3006	COG2080	2 iron, 2 sulfur cluster binding
Acry_3008	COG0456	acetyltransferase
Acry_3009	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Acry_3010	COG1917	Cupin 2, conserved barrel domain protein
Acry_3011	COG5285	phytanoyl-CoA dioxygenase
Acry_3012	COG0527	aspartate kinase activity
Acry_3013	COG2814	Major facilitator Superfamily
Acry_3016	COG1127	ABC transporter
Acry_3017	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Acry_3018	COG0861	Integral membrane protein TerC family
Acry_3019	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Acry_3029	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Acry_3030	COG3243	poly(R)-hydroxyalkanoic acid synthase
Acry_3039	COG0235	Class ii aldolase
Acry_3040	COG2020	methyltransferase activity
Acry_3041	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Acry_3048	COG0737	Belongs to the 5'-nucleotidase family
Acry_3055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Acry_3059	COG0436	Aminotransferase
Acry_3060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Acry_3061	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Acry_3063	COG0039	L-malate dehydrogenase activity
Acry_3084	COG2884	Cell division ATP-binding protein ftsE
Acry_3087	COG0326	Molecular chaperone. Has ATPase activity
Acry_3089	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Acry_3092	COG1914	H( )-stimulated, divalent metal cation uptake system
Acry_3093	COG0410	ABC transporter
Acry_3101	COG1309	transcriptional regulator
Acry_3104	COG0268	Binds directly to 16S ribosomal RNA
Acry_3115	COG3335	DDE superfamily endonuclease
Acry_3118	COG3547	Transposase (IS116 IS110 IS902 family)
Acry_3121	COG2433	Pfam Transposase IS66
Acry_3139	COG3459	Glycosyltransferase 36 associated
Acry_3143	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Acry_3145	COG0628	permease
Acry_3147	COG3237	CsbD-like
Acry_3156	COG3547	Transposase (IS116 IS110 IS902 family)
Acry_3166	COG1484	DNA-dependent DNA replication
Acry_3167	COG4584	PFAM Integrase catalytic
Acry_3170	COG3547	Transposase (IS116 IS110 IS902 family)
Acry_3181	COG4691	Plasmid stability protein
Acry_3194	COG3237	CsbD-like
Acry_3196	COG0628	permease
Acry_3206	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Acry_3209	COG3316	Transposase and inactivated derivatives
Acry_3212	COG3328	transposase activity
Acry_3221	COG4584	PFAM Integrase catalytic
Acry_3222	COG1484	DNA-dependent DNA replication
Acry_3224	COG2135	peptidase activity
Acry_3238	COG2814	Major facilitator Superfamily
Acry_3239	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Acry_3239	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Acry_3240	COG0640	Transcriptional regulator
Acry_3247	COG3328	transposase activity
Acry_3248	COG4584	PFAM Integrase catalytic
Acry_3252	COG3300	MHYT domain
Acry_3252	COG5001	Diguanylate cyclase
Acry_3257	COG0640	Transcriptional regulator
Acry_3258	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Acry_3258	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Acry_3259	COG2814	Major facilitator Superfamily
Acry_3264	COG4974	Belongs to the 'phage' integrase family
Acry_3265	COG4974	Belongs to the 'phage' integrase family
Acry_3266	COG4974	Belongs to the 'phage' integrase family
Acry_3269	COG4423	Transcription factor
Acry_3273	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Acry_3274	COG0640	Transcriptional regulator
Acry_3275	COG1475	DNA binding
Acry_3276	COG1192	Involved in chromosome partitioning
Acry_3278	COG1569	PIN domain
Acry_3279	COG3311	Transcriptional regulator
Acry_3284	COG0243	molybdopterin cofactor binding
Acry_3285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Acry_3285	COG1648	precorrin-2 dehydrogenase activity
Acry_3292	COG0587	DNA-directed DNA polymerase activity
Acry_3293	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Acry_3298	COG4584	PFAM Integrase catalytic
Acry_3299	COG1484	DNA-dependent DNA replication
Acry_3303	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Acry_3307	COG1414	Transcriptional regulator
Acry_3308	COG0583	DNA-binding transcription factor activity
Acry_3310	COG2070	2-Nitropropane dioxygenase
Acry_3314	COG1203	CRISPR-associated helicase, Cas3
Acry_3317	COG1857	crispr-associated protein
Acry_3320	COG1518	maintenance of DNA repeat elements
Acry_3326	COG0632	four-way junction helicase activity
Acry_3327	COG2255	four-way junction helicase activity
Acry_3334	COG5001	Diguanylate cyclase
Acry_3334	COG3300	MHYT domain
Acry_3347	COG4187	Peptidase family M20/M25/M40
Acry_3366	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Acry_3369	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Acry_3371	COG1396	sequence-specific DNA binding
Acry_3372	COG3550	peptidyl-serine autophosphorylation
Acry_3376	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Acry_3383	COG0028	Belongs to the TPP enzyme family
Acry_3384	COG0069	glutamate synthase activity
Acry_3387	COG3328	transposase activity
Acry_3392	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Acry_3393	COG2801	Transposase and inactivated derivatives
Acry_3398	COG2433	Pfam Transposase IS66
Acry_3399	COG4584	PFAM Integrase catalytic
Acry_3400	COG1484	DNA-dependent DNA replication
Acry_3403	COG1802	Transcriptional regulator
Acry_3404	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Acry_3406	COG0477	Major facilitator Superfamily
Acry_3408	COG1028	Short-chain dehydrogenase reductase Sdr
Acry_3418	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Acry_3419	COG0385	Bile acid
Acry_3420	COG1024	Enoyl-CoA hydratase
Acry_3420	COG1250	3-hydroxyacyl-CoA dehydrogenase
Acry_3421	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Acry_3422	COG1802	Transcriptional regulator
Acry_3426	COG2814	Major facilitator Superfamily
Acry_3437	COG0328	RNA-DNA hybrid ribonuclease activity
Acry_3446	COG3550	peptidyl-serine autophosphorylation
Acry_3456	COG0410	ABC transporter
Acry_3458	COG1172	Belongs to the binding-protein-dependent transport system permease family
Acry_3459	COG0559	Belongs to the binding-protein-dependent transport system permease family
Acry_3461	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Acry_3467	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Acry_3467	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Acry_3468	COG0640	Transcriptional regulator
Acry_3469	COG0517	IMP dehydrogenase activity
Acry_3470	COG4974	Belongs to the 'phage' integrase family
Acry_3478	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Acry_3479	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Acry_3482	COG5433	transposase activity
Acry_3484	COG1484	DNA-dependent DNA replication
Acry_3485	COG4584	PFAM Integrase catalytic
Acry_3488	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Acry_3493	COG2205	protein histidine kinase activity
Acry_3497	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Acry_3501	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Acry_3505	COG4974	Belongs to the 'phage' integrase family
Acry_3506	COG0582	viral genome integration into host DNA
Acry_3507	COG4974	Belongs to the 'phage' integrase family
Acry_3509	COG4584	PFAM Integrase catalytic
Acry_3510	COG1484	DNA-dependent DNA replication
Acry_3512	COG4423	Transcription factor
Acry_3515	COG1192	Involved in chromosome partitioning
Acry_3532	COG1522	sequence-specific DNA binding
Acry_3535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Acry_3536	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Acry_3541	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Acry_3561	COG0464	growth
Acry_3562	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Acry_3566	COG1285	pathogenesis
Acry_3567	COG4644	lycopene metabolic process
Acry_3570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Acry_3578	COG1414	Transcriptional regulator
Acry_3582	COG3727	T/G mismatch-specific endonuclease activity
Acry_3593	COG4584	PFAM Integrase catalytic
Acry_3594	COG1484	DNA-dependent DNA replication
Acry_3595	COG3547	Transposase (IS116 IS110 IS902 family)
Acry_3600	COG1192	Involved in chromosome partitioning
Acry_3603	COG3505	Type IV secretory pathway VirD4
Acry_3606	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Acry_3608	COG2814	Major facilitator Superfamily
Acry_3610	COG0811	peptide transport
Acry_3611	COG3415	Transposase
Acry_3613	COG3328	transposase activity
Acry_3615	COG3328	transposase activity