locus-tag	class	description
AXH35_00025	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AXH35_00115	ENOG41068JE	domain protein
AXH35_00210	ENOG4105EMD	TRANSCRIPTIONal
AXH35_00295	ENOG41082EK	Restriction modification system DNA (Specificity
AXH35_00370	ENOG4105CMM	transposase
AXH35_00385	ENOG4108IG5	Transcriptional regulator
AXH35_00395	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AXH35_00465	ENOG4105F7P	transcriptional regulator AsnC family
AXH35_00500	ENOG4105C5H	ABC transporter
AXH35_00575	ENOG4107Y2X	deaminase
AXH35_00580	ENOG4105E2A	Dehydrogenase
AXH35_00585	ENOG4107ZXU	DSBA oxidoreductase
AXH35_00600	ENOG4105C8T	Leucyl-tRNA synthetase
AXH35_00610	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
AXH35_00615	ENOG4105F8X	type iii restriction
AXH35_00625	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AXH35_00630	ENOG4107QW3	Sucrose phosphorylase
AXH35_00635	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AXH35_00655	ENOG4107TCW	O-succinylbenzoate synthase
AXH35_00660	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AXH35_00665	ENOG4105E4F	Isochorismate synthase
AXH35_00675	ENOG4107SIQ	Naphthoate synthase
AXH35_00685	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AXH35_00690	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AXH35_00700	ENOG4105CIG	ABC transporter
AXH35_00710	ENOG4105CSH	Transporter
AXH35_00720	ENOG4105DRS	transport system, permease
AXH35_00745	ENOG4105ECY	inositol monophosphatase
AXH35_00765	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AXH35_00770	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AXH35_00780	ENOG4105CPQ	Dehydrogenase
AXH35_00785	ENOG4105CTS	PTS system mannitol-specific
AXH35_00795	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AXH35_00800	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AXH35_00805	ENOG4107AQZ	Membrane
AXH35_00810	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AXH35_00820	ENOG4105WH1	Two component transcriptional regulator luxr family
AXH35_00825	ENOG4108IUX	(ABC) transporter
AXH35_00850	ENOG4108HGY	Proline imino-peptidase
AXH35_00865	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AXH35_00885	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AXH35_00895	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AXH35_00905	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AXH35_00910	ENOG4105CT1	(ABC) transporter
AXH35_00915	ENOG4105E5Q	amino acid AbC transporter
AXH35_00930	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AXH35_00940	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AXH35_00945	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
AXH35_00980	ENOG4105DSU	hydrolase
AXH35_00985	ENOG4105VKD	bioY protein
AXH35_00990	ENOG4108JJB	ABC transporter
AXH35_01005	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AXH35_01010	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AXH35_01015	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AXH35_01050	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AXH35_01070	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AXH35_01080	ENOG4107TE5	Lipid kinase
AXH35_01090	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AXH35_01095	ENOG4105K59	histidine triad (HIT) protein
AXH35_01105	ENOG4108ZP8	Acetolactate synthase small subunit
AXH35_01110	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AXH35_01130	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AXH35_01135	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AXH35_01140	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AXH35_01150	ENOG4105ERH	Fumarylacetoacetate hydrolase
AXH35_01170	ENOG41069M3	Transcriptional regulator
AXH35_01175	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AXH35_01180	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AXH35_01190	ENOG4105CPF	Cell wall formation (By similarity)
AXH35_01205	ENOG4107QZI	cell division protein FtsK
AXH35_01215	ENOG4105KAF	membrAne
AXH35_01230	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AXH35_01235	ENOG4105CAK	Cell division ATP-binding protein ftsE
AXH35_01240	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
AXH35_01245	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AXH35_01255	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AXH35_01260	ENOG4105CAS	nag kinase
AXH35_01265	ENOG4105C8Y	Acetylornithine aminotransferase
AXH35_01270	ENOG4105DBV	ornithine carbamoyltransferase
AXH35_01275	ENOG4105CH7	arginosuccinase
AXH35_01290	ENOG4108UJU	UPF0301 protein
AXH35_01295	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXH35_01300	ENOG4105BZU	Histidine kinase
AXH35_01305	ENOG4105G3P	Lipoprotein lpqB
AXH35_01315	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
AXH35_01325	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AXH35_01345	ENOG4105DB7	PHP domain protein
AXH35_01355	ENOG4105C31	Tryptophanyl-tRNA synthetase
AXH35_01380	ENOG4105VEQ	Cold shock protein
AXH35_01385	ENOG4105C4R	Atp-dependent dna helicase
AXH35_01405	ENOG4107QKA	exodeoxyribonuclease V beta
AXH35_01410	ENOG4105DSY	exodeoxyribonuclease V, gamma
AXH35_01435	ENOG41063PX	domain protein
AXH35_01445	ENOG4105DJZ	UPF0182 protein
AXH35_01455	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AXH35_01475	ENOG4105DEF	Extracellular solute-binding protein, family 5
AXH35_01485	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AXH35_01495	ENOG4108JQ6	ABC transporter
AXH35_01500	ENOG4108JQ1	Dehydrogenase
AXH35_01505	ENOG4107TK4	histidinol-phosphate phosphatase
AXH35_01515	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AXH35_01520	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AXH35_01530	ENOG4105EMN	RNA polymerase sigma factor
AXH35_01555	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AXH35_01565	ENOG4108URH	decarboxylase
AXH35_01575	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AXH35_01580	ENOG4105D6E	homoserine dehydrogenase
AXH35_01585	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AXH35_01595	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AXH35_01600	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AXH35_01605	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AXH35_01685	ENOG4105CEY	Amp-dependent synthetase and ligase
AXH35_01700	ENOG4105CAQ	asparagine synthetase
AXH35_01710	ENOG4105D7W	serine acetyltransferase
AXH35_01725	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
AXH35_01730	ENOG4106DE0	ATP synthase
AXH35_01735	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
AXH35_01740	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AXH35_01745	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AXH35_01750	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AXH35_01755	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AXH35_01760	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AXH35_01790	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
AXH35_01815	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
AXH35_01825	ENOG4107UVD	Beta-phosphoglucomutase family hydrolase
AXH35_01840	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AXH35_01845	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
AXH35_01850	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
AXH35_01870	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AXH35_01885	ENOG4108IY8	ABC, transporter
AXH35_01910	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AXH35_01915	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AXH35_01920	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AXH35_01940	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AXH35_01945	ENOG4105CRQ	synthase (Component I)
AXH35_01960	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AXH35_01970	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AXH35_01975	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AXH35_01980	ENOG4105CBC	glutamate synthase
AXH35_01990	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_02000	ENOG4105DRS	transport system, permease
AXH35_02035	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AXH35_02040	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AXH35_02045	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AXH35_02050	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AXH35_02055	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AXH35_02060	ENOG4105CDY	transcriptional regulatory protein
AXH35_02065	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AXH35_02070	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AXH35_02075	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AXH35_02090	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AXH35_02095	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AXH35_02105	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AXH35_02110	ENOG4105D98	threonine synthase
AXH35_02115	ENOG4105C99	atpase involved in dna repair
AXH35_02120	ENOG4105C5X	domain protein
AXH35_02125	ENOG4105CUT	histidyl-tRNA synthetase
AXH35_02130	ENOG4105CIZ	coA-substrate-specific enzyme activase
AXH35_02135	ENOG4107MVR	Transcriptional regulator
AXH35_02150	ENOG4105C9M	aspartyl-trna synthetase
AXH35_02185	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AXH35_02190	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AXH35_02200	ENOG4105E2X	shikimate dehydrogenase
AXH35_02205	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AXH35_02210	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AXH35_02215	ENOG4105D49	3-dehydroquinate synthase
AXH35_02225	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AXH35_02230	ENOG410803B	Involved in the transcription termination process (By similarity)
AXH35_02240	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AXH35_02245	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AXH35_02255	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AXH35_02260	ENOG4107QRT	dEAD DEAH box helicase
AXH35_02265	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
AXH35_02295	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AXH35_02305	ENOG4105DJV	ribulose-phosphate 3-epimerase
AXH35_02315	ENOG4105C3R	Methionine synthase
AXH35_02330	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
AXH35_02335	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
AXH35_02345	ENOG4105CAT	Cytidine monophosphate kinase
AXH35_02350	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AXH35_02360	ENOG4108Z9K	Osmotically inducible protein
AXH35_02385	ENOG4105DZR	Type I site-specific deoxyribonuclease
AXH35_02480	ENOG4107S1Q	Phosphatase
AXH35_02490	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AXH35_02510	ENOG4105C8Y	Acetylornithine aminotransferase
AXH35_02520	ENOG4105DNP	FAD linked oxidase domain protein
AXH35_02610	ENOG4105DJ2	Major Facilitator Superfamily
AXH35_02630	ENOG4105CYC	Transferase
AXH35_02635	ENOG4105DWV	Homoserine O-trans-acetylase
AXH35_02640	ENOG4105DWV	Homoserine O-trans-acetylase
AXH35_02650	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AXH35_02655	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AXH35_02660	ENOG4105Q70	
AXH35_02670	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
AXH35_02675	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AXH35_02685	ENOG4105D22	carbon starvation protein
AXH35_02700	ENOG4105CUB	amino acid
AXH35_02715	ENOG4107QZ7	Cellulose synthase catalytic subunit
AXH35_02750	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AXH35_02755	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AXH35_02760	ENOG4107TE5	Lipid kinase
AXH35_02765	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AXH35_02770	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AXH35_02780	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
AXH35_02785	ENOG4107H3J	ribonuclease
AXH35_02805	ENOG4108UW8	fha domain-containing protein
AXH35_02810	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AXH35_02835	ENOG4105E2K	Glycosyl transferase (Group 1
AXH35_02840	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
AXH35_02855	ENOG4105C22	threonyL-tRNA synthetase
AXH35_02860	ENOG4105DQ4	alcohol dehydrogenase
AXH35_02885	ENOG4108ZJ4	polysaccharide deacetylase
AXH35_02915	ENOG4105CSR	polyphosphate kinase 2
AXH35_02920	ENOG4105E0X	reductase
AXH35_02935	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AXH35_02940	ENOG4107QM5	aconitate hydratase
AXH35_02945	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AXH35_02950	ENOG4105C0X	amino acid
AXH35_02955	ENOG4107VEG	TrkA-N domain protein
AXH35_02975	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AXH35_03010	ENOG4105EPD	Oligopeptide transporter, Opt family
AXH35_03020	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXH35_03040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXH35_03055	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AXH35_03065	ENOG4105CQ7	ATP-dependent helicase
AXH35_03085	ENOG4105DHP	deoxycytidine triphosphate deaminase
AXH35_03090	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AXH35_03110	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AXH35_03115	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AXH35_03120	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AXH35_03435	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AXH35_03440	ENOG4107WI4	Aldose-1-epimerase
AXH35_03445	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AXH35_03450	ENOG4105KC9	Modulates RecA activity (By similarity)
AXH35_03455	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AXH35_03465	ENOG4105E98	transcriptional regulator DeoR family
AXH35_03475	ENOG4105CEV	competence damage-inducible protein
AXH35_03485	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AXH35_03515	ENOG4107T52	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AXH35_03520	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AXH35_03525	ENOG4107TYT	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AXH35_03530	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
AXH35_03535	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AXH35_03540	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AXH35_03545	ENOG4105CD3	dihydroorotase
AXH35_03560	ENOG4105CPC	Aldo Keto reductase
AXH35_03570	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AXH35_03585	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AXH35_03600	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AXH35_03615	ENOG4105DFA	alanine racemase domain protein
AXH35_03625	ENOG4107QVM	von Willebrand factor, type A
AXH35_03635	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AXH35_03665	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AXH35_03675	ENOG4108QVN	serine threonine protein kinase
AXH35_03685	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AXH35_03695	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AXH35_03705	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AXH35_03725	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
AXH35_03750	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AXH35_03755	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AXH35_03760	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AXH35_03785	ENOG4105E33	succinate dehydrogenase
AXH35_03800	ENOG4105CVK	Glutamate decarboxylase
AXH35_03810	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AXH35_03815	ENOG4108IYU	L-aspartate oxidase
AXH35_03825	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AXH35_03835	ENOG41090R7	Ferric uptake
AXH35_03870	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AXH35_03875	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
AXH35_03890	ENOG4105CPC	Aldo Keto reductase
AXH35_03900	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AXH35_03910	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_03915	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
AXH35_03925	ENOG4107QNK	)-transporter
AXH35_03945	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
AXH35_03955	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_03960	ENOG4105DRS	transport system, permease
AXH35_03990	ENOG4105C0P	Mg chelatase subunit ChlI
AXH35_03995	ENOG41080R2	UPF0102 protein
AXH35_04005	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AXH35_04010	ENOG4107QYR	Signal peptidase i
AXH35_04015	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AXH35_04020	ENOG4105E33	succinate dehydrogenase
AXH35_04035	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AXH35_04040	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AXH35_04045	ENOG41082KU	UPF0109 protein
AXH35_04050	ENOG4105K5M	30s ribosomal protein S16
AXH35_04085	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
AXH35_04130	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AXH35_04135	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AXH35_04140	ENOG41084BZ	50S ribosomal protein L32
AXH35_04150	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AXH35_04155	ENOG4106H78	methyltransferase
AXH35_04175	ENOG4105VB9	50S ribosomal protein l28
AXH35_04180	ENOG4105CN5	Metallo-Beta-Lactamase
AXH35_04190	ENOG4105C7K	acetolactate synthase
AXH35_04200	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AXH35_04205	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AXH35_04210	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AXH35_04230	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AXH35_04245	ENOG410787A	Pts system, glucitol sorbitol-specific
AXH35_04250	ENOG4105DZY	Pts system, glucitol sorbitol-specific
AXH35_04255	ENOG4105VI0	Pts system, glucitol sorbitol-specific
AXH35_04265	ENOG4108MDK	Dehydrogenase
AXH35_04270	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AXH35_04275	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AXH35_04280	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AXH35_04290	ENOG4105CHV	Transcription elongation factor NusA
AXH35_04295	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
AXH35_04315	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AXH35_04355	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AXH35_04360	ENOG4105DZP	Membrane-associated zinc metalloprotease
AXH35_04370	ENOG4105D82	Glutamate dehydrogenase
AXH35_04375	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AXH35_04380	ENOG4105KNE	Phosphatidate cytidylyltransferase
AXH35_04385	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AXH35_04390	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AXH35_04395	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AXH35_04400	ENOG4105CE9	30S ribosomal protein S2
AXH35_04405	ENOG4108KDT	Molybdate metabolism regulator
AXH35_04420	ENOG4105DEG	Vwa containing coxe family protein
AXH35_04435	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AXH35_04445	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AXH35_04470	ENOG4105DHU	Bile acid
AXH35_04485	ENOG4105DKW	ABC transporter
AXH35_04490	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AXH35_04500	ENOG4108IJ0	Aspartate ammonia-lyase
AXH35_04515	ENOG4105CHR	reductase
AXH35_04530	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AXH35_04545	ENOG4105C5H	ABC transporter
AXH35_04560	ENOG4108UW5	maltose o-acetyltransferase
AXH35_04590	ENOG4108UNV	SUF system FeS assembly protein, NifU family
AXH35_04595	ENOG4105C9B	Cysteine desulfurase
AXH35_04600	ENOG4105C3K	feS assembly ATPase SufC
AXH35_04615	ENOG4105DIW	FeS assembly protein SUFB
AXH35_04630	ENOG4105D56	permease protein
AXH35_04635	ENOG4105EG2	ABC transporter, permease
AXH35_04640	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_04645	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AXH35_04660	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
AXH35_04665	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AXH35_04680	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
AXH35_04690	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AXH35_04705	ENOG4107RE3	peptidase, S41
AXH35_04715	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AXH35_04720	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AXH35_04725	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AXH35_04730	ENOG4105DSF	transport protein
AXH35_04735	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AXH35_04755	ENOG4105CRK	lysyL-tRNA synthetase
AXH35_04775	ENOG4108YZG	isomerase
AXH35_04790	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AXH35_04795	ENOG4105MC2	DSBA oxidoreductase
AXH35_04810	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AXH35_04820	ENOG4105DXB	Major Facilitator superfamily
AXH35_04835	ENOG4108IQE	Amp-dependent synthetase and ligase
AXH35_04850	ENOG4105CQB	FAD linked oxidase domain protein
AXH35_04875	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AXH35_04885	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AXH35_04895	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AXH35_04920	ENOG4105C0D	helicase
AXH35_04930	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AXH35_04935	ENOG4105WH1	Two component transcriptional regulator luxr family
AXH35_04940	ENOG4108XG2	Histidine kinase
AXH35_04950	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AXH35_04975	ENOG4105CJ1	ABC, transporter
AXH35_04995	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AXH35_05000	ENOG4105CUB	amino acid
AXH35_05010	ENOG4105C0B	DNA polymerase III (alpha subunit)
AXH35_05025	ENOG4105DFU	Cell wall formation (By similarity)
AXH35_05045	ENOG41089BK	Glutamine amido-transferase
AXH35_05050	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AXH35_05075	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AXH35_05085	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AXH35_05090	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AXH35_05095	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AXH35_05100	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AXH35_05110	ENOG4105CE1	Ferrous iron transport protein b
AXH35_05125	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AXH35_05195	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
AXH35_05205	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AXH35_05220	ENOG4108KGH	TRANSCRIPTIONal
AXH35_05240	ENOG4105EC3	peptidase S51, dipeptidase E
AXH35_05250	ENOG4105D8K	carboxyl transferase
AXH35_05260	ENOG4107WR6	Maf-like protein
AXH35_05270	ENOG4105CEU	Arginine dihydrolase
AXH35_05285	ENOG4105DWF	phosphomethylpyrimidine kinase
AXH35_05295	ENOG4108JIK	carboxylase
AXH35_05315	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
AXH35_05330	ENOG4105C8Y	Acetylornithine aminotransferase
AXH35_05335	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
AXH35_05340	ENOG41088D5	d-proline reductase
AXH35_05350	ENOG4107T4V	d-proline reductase
AXH35_05360	ENOG4105CTU	Proline racemase
AXH35_05370	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AXH35_05390	ENOG4105UIB	(ABC) transporter
AXH35_05395	ENOG4108JQ9	ABC transporter
AXH35_05400	ENOG4107TFB	basic membrane
AXH35_05430	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AXH35_05435	ENOG4108EKI	Dehydrogenase
AXH35_05445	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AXH35_05455	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AXH35_05465	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AXH35_05470	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AXH35_05500	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AXH35_05520	ENOG4105D01	(LipO)protein
AXH35_05525	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AXH35_05530	ENOG4108UMI	ABC transporter, permease
AXH35_05540	ENOG4105Y3U	Transglycosylase-associated protein
AXH35_05545	ENOG4105WH1	Two component transcriptional regulator luxr family
AXH35_05570	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AXH35_05575	ENOG4105D7W	serine acetyltransferase
AXH35_05580	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
AXH35_05590	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AXH35_05595	ENOG41072RD	Membrane
AXH35_05600	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AXH35_05605	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AXH35_05625	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
AXH35_05645	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AXH35_05660	ENOG4108097	ATP-binding protein
AXH35_05665	ENOG4105C1J	atp-dependent rna helicase
AXH35_05680	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AXH35_05685	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AXH35_05690	ENOG4107QVI	Methyltransferase, type 11
AXH35_05695	ENOG4105CS9	pantothenic acid kinase
AXH35_05705	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AXH35_05710	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AXH35_05715	ENOG4108UJD	30S ribosomal protein S9
AXH35_05720	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AXH35_05730	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AXH35_05740	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AXH35_05745	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AXH35_05750	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AXH35_05760	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
AXH35_05765	ENOG4108JJB	ABC transporter
AXH35_05775	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AXH35_05780	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AXH35_05790	ENOG4108MJN	Glycosyl Transferase
AXH35_05795	ENOG4108ZT0	50S ribosomal protein l17
AXH35_05800	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AXH35_05805	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AXH35_05810	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AXH35_05815	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AXH35_05820	ENOG41067V7	50S ribosomal protein L36
AXH35_05825	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AXH35_05845	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AXH35_05880	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AXH35_05885	ENOG410849U	50S ribosomal protein L30
AXH35_05890	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AXH35_05895	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AXH35_05900	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AXH35_05905	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AXH35_05910	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AXH35_05915	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AXH35_05920	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AXH35_05925	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AXH35_05930	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AXH35_05935	ENOG4105DRS	transport system, permease
AXH35_05950	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_05960	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AXH35_05965	ENOG41082SA	50s ribosomal protein l29
AXH35_05970	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AXH35_05975	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AXH35_05980	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AXH35_05985	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AXH35_05990	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AXH35_05995	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AXH35_06000	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AXH35_06005	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AXH35_06010	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AXH35_06015	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AXH35_06020	ENOG4105CX6	glutaminyL-tRNA synthetase
AXH35_06035	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AXH35_06040	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AXH35_06045	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AXH35_06050	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AXH35_06055	ENOG4105EE0	oxidoreductase
AXH35_06070	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AXH35_06075	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AXH35_06080	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AXH35_06090	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AXH35_06095	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AXH35_06100	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AXH35_06115	ENOG4105XT2	Transcriptional regulator
AXH35_06120	ENOG4107R4N	Cell wall formation (By similarity)
AXH35_06130	ENOG410900P	UPF0336 protein
AXH35_06135	ENOG4105WDJ	50S ribosomal protein L33
AXH35_06175	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXH35_06180	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXH35_06185	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXH35_06190	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AXH35_06195	ENOG4105DQU	oxidoreductase, subunit beta
AXH35_06200	ENOG4105C9K	Endothelin-converting enzyme 1
AXH35_06215	ENOG4107R9N	ABC transporter
AXH35_06220	ENOG4105C2J	ABC transporter
AXH35_06225	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AXH35_06235	ENOG4107FQ9	ethanolamine ammonia-lyase
AXH35_06240	ENOG4105CPD	ethanolamine ammonia-lyase
AXH35_06255	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXH35_06270	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXH35_06275	ENOG4105DF2	NADH dehydrogenase subunit j
AXH35_06280	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXH35_06285	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AXH35_06290	ENOG4108IEH	NADH dehydrogenase subunit g
AXH35_06295	ENOG4107QIZ	NADH dehydrogenase
AXH35_06305	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXH35_06310	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AXH35_06315	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXH35_06325	ENOG4105P52	geranylgeranyl reductase
AXH35_06330	ENOG4105E4F	Isochorismate synthase
AXH35_06350	ENOG4105CJ1	ABC, transporter
AXH35_06355	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AXH35_06365	ENOG4105BZ1	(ABC) transporter
AXH35_06385	ENOG4105CMT	Dihydroxyacetone kinase
AXH35_06390	ENOG4108UTZ	Dihydroxyacetone kinase
AXH35_06395	ENOG4105VDH	Dihydroxyacetone kinase
AXH35_06435	ENOG4105DEN	Luciferase family
AXH35_06490	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AXH35_06505	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AXH35_06600	ENOG4108IV0	ABC, transporter
AXH35_06605	ENOG4105C0Z	ABC transporter
AXH35_06610	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AXH35_06615	ENOG4105C32	Amino acid ABC transporter (Permease)
AXH35_06620	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
AXH35_06645	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AXH35_06660	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AXH35_06685	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AXH35_06700	ENOG4105HDK	L-asparaginase
AXH35_06715	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AXH35_06720	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AXH35_06725	ENOG4105C8V	SAICAR synthetase
AXH35_06730	ENOG4105D3R	alkyl hydroperoxide reductase
AXH35_06735	ENOG4108JU3	Alkyl hydroperoxide reductase
AXH35_06745	ENOG4105C83	adenylosuccinate lyase
AXH35_06750	ENOG4105C12	Phosphoribosylglycinamide synthetase
AXH35_06755	ENOG4105VJK	Transcription factor
AXH35_06760	ENOG4105ZGE	Toxic component of a toxin-antitoxin (TA) module. A
AXH35_06765	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AXH35_06780	ENOG4105XTG	Pfam:DUF156
AXH35_06785	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AXH35_06800	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
AXH35_06805	ENOG4105CI3	gtp-binding protein typa
AXH35_06825	ENOG4108SVG	May play a role in the intracellular transport of hydrophobic ligands
AXH35_06830	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AXH35_06860	ENOG4107NHD	transcriptional regulator
AXH35_06865	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AXH35_06890	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AXH35_06895	ENOG4105KDC	50s ribosomal protein l28
AXH35_06900	ENOG41068HZ	50S ribosomal protein L32
AXH35_06905	ENOG4105NRA	50s ribosomal protein l31 type b
AXH35_06910	ENOG4105W0E	50S ribosomal protein L33
AXH35_06920	ENOG4105CKI	cobalamin synthesis protein
AXH35_06935	ENOG4105CC5	ABC transporter
AXH35_06940	ENOG4105DIK	(ABC) transporter
AXH35_06950	ENOG4105DSE	periplasmic solute binding protein
AXH35_06955	ENOG4108MES	Periplasmic binding protein
AXH35_06960	ENOG4105DQ5	transport system permease protein
AXH35_06965	ENOG4108IHU	transport system permease protein
AXH35_06970	ENOG4105E0A	ABC, transporter
AXH35_06990	ENOG4105C01	Dihydroxy-acid dehydratase
AXH35_06995	ENOG4105C7B	Threonine dehydratase
AXH35_07010	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AXH35_07030	ENOG4105CRE	cytochrome C
AXH35_07040	ENOG4107QIV	Cytochrome c biogenesis protein
AXH35_07045	ENOG4107ZT5	Thiol disulfide interchange protein
AXH35_07050	ENOG4108RH7	phosphoglycerate mutase
AXH35_07055	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AXH35_07060	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
AXH35_07090	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
AXH35_07100	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AXH35_07105	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AXH35_07125	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AXH35_07130	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AXH35_07135	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AXH35_07145	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AXH35_07155	ENOG4105D52	delta-aminolevulinic acid dehydratase
AXH35_07160	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AXH35_07175	ENOG4108UCS	ABC, transporter
AXH35_07185	ENOG4105DP9	ABC transporter
AXH35_07195	ENOG4107ZXI	Rhomboid family
AXH35_07250	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AXH35_07260	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AXH35_07280	ENOG4105KRF	dihydroneopterin aldolase
AXH35_07285	ENOG4105EEI	dihydropteroate synthase
AXH35_07290	ENOG4105EUJ	GTP cyclohydrolase i
AXH35_07300	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AXH35_07305	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AXH35_07315	ENOG4105F0N	pyrophosphate phospho-hydrolase
AXH35_07325	ENOG4105I82	acetyl xylan esterase
AXH35_07330	ENOG4105M4E	phosphohistidine phosphatase, SixA
AXH35_07380	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
AXH35_07385	ENOG4108JQ6	ABC transporter
AXH35_07390	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AXH35_07395	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AXH35_07425	ENOG4108YYH	Nadph-dependent fmn reductase
AXH35_07470	ENOG4105MA4	psp1 domain protein
AXH35_07480	ENOG4107QRG	dna polymerase iii
AXH35_07485	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AXH35_07495	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AXH35_07505	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AXH35_07510	ENOG4108I5C	dEAD DEAH box helicase
AXH35_07600	ENOG4105P8F	nudix hydrolase
AXH35_07630	ENOG4105BZ4	penicillin-binding protein
AXH35_07660	ENOG4107QK5	Homocysteine s-methyltransferase
AXH35_07665	ENOG410834F	Transcriptional regulator
AXH35_07695	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AXH35_07700	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AXH35_07705	ENOG4105C3U	ABC transporter
AXH35_07710	ENOG4108JQ7	(ABC) transporter
AXH35_07725	ENOG4105D1Q	UPF0246 protein
AXH35_07740	ENOG4108HMQ	sugar kinase
AXH35_07745	ENOG4107Z1W	Fructose transport system kinase
AXH35_07765	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AXH35_07775	ENOG4107QI1	Mate efflux family protein
AXH35_07815	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AXH35_07825	ENOG4105WH1	Two component transcriptional regulator luxr family
AXH35_07830	ENOG4105CH6	catalase
AXH35_07850	ENOG4105DQE	DNA ligase
AXH35_07860	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AXH35_07875	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AXH35_07890	ENOG4107S2Z	UPF0761 membrane protein
AXH35_07910	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AXH35_07930	ENOG4105WS7	Cation transport regulator
AXH35_07935	ENOG4107SET	aldo keto reductase
AXH35_07950	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AXH35_07975	ENOG4107QUV	Domain protein
AXH35_08000	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AXH35_08025	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_08030	ENOG4105C2X	Arabinose 5-phosphate isomerase
AXH35_08060	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
AXH35_08070	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_08085	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
AXH35_08095	ENOG4105DZC	cytosine deaminase
AXH35_08110	ENOG4105C5I	Dehydrogenase
AXH35_08120	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AXH35_08145	ENOG4105DQR	SNARE associated Golgi
AXH35_08155	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AXH35_08160	ENOG4105BZU	Histidine kinase
AXH35_08165	ENOG4105ETX	regulatoR
AXH35_08170	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AXH35_08180	ENOG4105C4B	ABC transporter, permease
AXH35_08190	ENOG4105DQ4	alcohol dehydrogenase
AXH35_08195	ENOG4105DKT	Transcriptional regulator
AXH35_08200	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AXH35_08205	ENOG4105CPQ	Dehydrogenase
AXH35_08210	ENOG4105CMT	Dihydroxyacetone kinase
AXH35_08215	ENOG4105C29	acyl-CoA thioesterase
AXH35_08225	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AXH35_08230	ENOG41090U3	tautomerase
AXH35_08260	ENOG4108UMN	azlc family
AXH35_08280	ENOG4105D7A	ATP-binding protein
AXH35_08295	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AXH35_08300	ENOG4108IJ8	ABC transporter
AXH35_08310	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
AXH35_08320	ENOG4107S1E	Beta-lactamase
AXH35_08355	ENOG4108Z6B	deaminase
AXH35_08365	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AXH35_08390	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AXH35_08395	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AXH35_08400	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AXH35_08425	ENOG4108KGH	TRANSCRIPTIONal
AXH35_08430	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_08435	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AXH35_08465	ENOG4105CDH	Citrulline--aspartate ligase
AXH35_08485	ENOG4108K4B	hydrolase
AXH35_08490	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_08505	ENOG4105EG2	ABC transporter, permease
AXH35_08525	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AXH35_08545	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AXH35_08555	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AXH35_08565	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
AXH35_08570	ENOG4105CPP	Dehydrogenase, E1 component
AXH35_08580	ENOG4107VFM	Dehydrogenase
AXH35_08605	ENOG4105CSH	Transporter
AXH35_08610	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AXH35_08615	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AXH35_08620	ENOG4105ENR	peptidase, M24
AXH35_08630	ENOG4108JPW	Aminotransferase
AXH35_08660	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AXH35_08665	ENOG4105C5I	Dehydrogenase
AXH35_08740	ENOG4106H3A	restriction
AXH35_08765	ENOG4105I7V	membrAne
AXH35_08775	ENOG4105GR3	Histidine kinase
AXH35_08790	ENOG4108HKT	sucrose-6-phosphate hydrolase
AXH35_08795	ENOG4105CSH	Transporter
AXH35_08815	ENOG4105DSQ	Nitric oxide reductase
AXH35_08850	ENOG4107QWR	cellulase (EC 3.2.1.4)
AXH35_08860	ENOG4105CG3	alpha amylase, catalytic region
AXH35_08890	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AXH35_08900	ENOG4105BZ7	extracellular solute-binding protein family 1
AXH35_08905	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
AXH35_08910	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
AXH35_08915	ENOG4105KT7	mgtC SapB transporter
AXH35_08930	ENOG4105EBR	Carboxylesterase
AXH35_08935	ENOG4105DKQ	ROK family
AXH35_08945	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
AXH35_08950	ENOG4105DRS	transport system, permease
AXH35_08955	ENOG4105CG3	alpha amylase, catalytic region
AXH35_08970	ENOG4105BZ1	(ABC) transporter
AXH35_08975	ENOG4105BZ1	(ABC) transporter
AXH35_08990	ENOG4105CIF	Ornithine Cyclodeaminase
AXH35_09010	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
AXH35_09025	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_09040	ENOG41062D9	Histidine kinase
AXH35_09050	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AXH35_09060	ENOG4105PGM	cation diffusion facilitator family transporter
AXH35_09075	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AXH35_09085	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AXH35_09095	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AXH35_09100	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AXH35_09110	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
AXH35_09115	ENOG4105DBE	peroxidase
AXH35_09135	ENOG4108IQE	Amp-dependent synthetase and ligase
AXH35_09150	ENOG4108IXY	short-chain dehydrogenase reductase
AXH35_09195	ENOG4105CQB	FAD linked oxidase domain protein
AXH35_09200	ENOG4105BZU	Histidine kinase
AXH35_09205	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AXH35_09210	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
AXH35_09215	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
AXH35_09220	ENOG4105C5I	Dehydrogenase
AXH35_09225	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
AXH35_09235	ENOG4105C85	amino acid
AXH35_09350	ENOG4108TFM	Kinase, PfkB family
AXH35_09360	ENOG4108Z66	YbaK ebsC protein
AXH35_09370	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AXH35_09380	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_09395	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
AXH35_09400	ENOG4105KVH	Transcriptional regulator
AXH35_09405	ENOG4105CIS	alcohol dehydrogenase
AXH35_09415	ENOG4108HKT	sucrose-6-phosphate hydrolase
AXH35_09420	ENOG4105D7K	pfkb domain protein
AXH35_09425	ENOG410839S	Toxic component of a toxin-antitoxin (TA) module (By similarity)
AXH35_09440	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
AXH35_09445	ENOG4107QZF	nitrite reductase NADPH large subunit
AXH35_09450	ENOG4105IDI	abc transporter atp-binding protein
AXH35_09455	ENOG4108QVN	serine threonine protein kinase
AXH35_09465	ENOG4105CTQ	phosphohexokinase
AXH35_09470	ENOG4105DCF	alanine dehydrogenase
AXH35_09475	ENOG4105E5G	Alpha beta hydrolase fold
AXH35_09520	ENOG4105K6T	rare lipoprotein A
AXH35_09530	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AXH35_09545	ENOG4105E2D	ec 3.2.1.52
AXH35_09570	ENOG4105CMQ	Chloride channel
AXH35_09580	ENOG4105CAG	UPF0210 protein
AXH35_09595	ENOG4105C9Q	fumarate hydratase class II
AXH35_09600	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AXH35_09605	ENOG41064HX	Suppressor of fused protein (SUFU)
AXH35_09615	ENOG4105CTZ	aminopeptidase c
AXH35_09620	ENOG4105CIG	ABC transporter
AXH35_09635	ENOG4105F27	Major Facilitator
AXH35_09645	ENOG4105E98	transcriptional regulator DeoR family
AXH35_09650	ENOG4105CXT	aspartate transcarbamylase
AXH35_09665	ENOG4105D8X	mechanosensitive ion channel
AXH35_09675	ENOG4105BZW	Glycerate kinase
AXH35_09685	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AXH35_09690	ENOG4105C26	Dehydrogenase
AXH35_09695	ENOG4105C09	Bile acid
AXH35_09700	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AXH35_09715	ENOG4105D9P	serine threonine protein kinase
AXH35_09730	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AXH35_09735	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AXH35_09740	ENOG4107RHR	regulatoR
AXH35_09750	ENOG4105C0H	protease
AXH35_09765	ENOG4105DRS	transport system, permease
AXH35_09785	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_09790	ENOG4105C3M	thioredoxin reductase
AXH35_09795	ENOG4105KVH	Transcriptional regulator
AXH35_09810	ENOG4105K63	Thioredoxin
AXH35_09855	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AXH35_09885	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AXH35_09905	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AXH35_09930	ENOG4105CVN	desaturase
AXH35_09945	ENOG4106A3M	Cytochrome p-450
AXH35_09955	ENOG4105C28	cystathionine
AXH35_09970	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AXH35_10005	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AXH35_10015	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
AXH35_10020	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AXH35_10025	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_10035	ENOG4107ZR7	Membrane
AXH35_10040	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
AXH35_10045	ENOG4105CK5	oxidoreductase
AXH35_10060	ENOG4107QNK	)-transporter
AXH35_10070	ENOG4107QNK	)-transporter
AXH35_10075	ENOG4107P2S	Transcriptional regulator
AXH35_10080	ENOG4105F0H	myo-inositol catabolism protein
AXH35_10085	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AXH35_10090	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
AXH35_10095	ENOG4105C26	Dehydrogenase
AXH35_10110	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AXH35_10115	ENOG4105CPF	Cell wall formation (By similarity)
AXH35_10130	ENOG4105DQE	DNA ligase
AXH35_10140	ENOG4107QJE	Chromosome Partitioning Protein
AXH35_10150	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AXH35_10155	ENOG4105KPY	Small multidrug resistance protein
AXH35_10165	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AXH35_10175	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AXH35_10180	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AXH35_10185	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXH35_10190	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXH35_10195	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AXH35_10205	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AXH35_10210	ENOG4105K7N	UPF0232 protein
AXH35_10220	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXH35_10225	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AXH35_10230	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
AXH35_10240	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_10245	ENOG4105C2J	ABC transporter
AXH35_10250	ENOG4105CNN	ABC, transporter
AXH35_10255	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AXH35_10260	ENOG4108RVA	ribokinase
AXH35_10265	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AXH35_10290	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AXH35_10300	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
AXH35_10305	ENOG4106F59	XRE family Transcriptional regulator
AXH35_10350	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AXH35_10365	ENOG4105C6K	Malic enzyme
AXH35_10370	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AXH35_10375	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AXH35_10385	ENOG4105C26	Dehydrogenase
AXH35_10390	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AXH35_10410	ENOG4105E5D	amino acid
AXH35_10420	ENOG4107W7X	Aldolase
AXH35_10430	ENOG4105CPQ	Dehydrogenase
AXH35_10435	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
AXH35_10440	ENOG4105DT3	PTS system, galactitol-specific IIc component
AXH35_10450	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AXH35_10455	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AXH35_10475	ENOG4105DVE	abc transporter atp-binding protein
AXH35_10485	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
AXH35_10490	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AXH35_10495	ENOG4105E5Q	amino acid AbC transporter
AXH35_10500	ENOG4105CDA	abc transporter atp-binding protein
AXH35_10505	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AXH35_10520	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AXH35_10525	ENOG4105I1K	ABC transporter
AXH35_10530	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AXH35_10550	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AXH35_10615	ENOG4105C26	Dehydrogenase
AXH35_10625	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AXH35_10655	ENOG4105CKU	formyltetrahydrofolate synthetase
AXH35_10680	ENOG4105C19	ABC transporter
AXH35_10685	ENOG4105WH1	Two component transcriptional regulator luxr family
AXH35_10695	ENOG4105YES	addiction module antidote protein
AXH35_10700	ENOG4105VUH	addiction module killer protein
AXH35_10705	ENOG4105E0Y	RtcB Protein
AXH35_10715	ENOG4105BZ1	(ABC) transporter
AXH35_10750	ENOG4105BZU	Histidine kinase
AXH35_10755	ENOG4105EDW	glycosyl transferase, family 39
AXH35_10760	ENOG4105BZU	Histidine kinase
AXH35_10770	ENOG4105GR3	Histidine kinase
AXH35_10775	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXH35_10785	ENOG4107R16	Multicopper oxidase
AXH35_10810	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AXH35_10825	ENOG410635A	Membrane
AXH35_10850	ENOG4105CV8	reductase
AXH35_10900	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AXH35_10920	ENOG41067SE	Tetr family transcriptional regulator
AXH35_10925	ENOG4105EYF	MMPL domain protein
AXH35_10945	ENOG4108JQ1	Dehydrogenase
AXH35_10950	ENOG4105BZ4	penicillin-binding protein
AXH35_10960	ENOG4105C2C	drug resistance transporter, Bcr CflA
AXH35_10970	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AXH35_10975	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AXH35_10980	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
AXH35_10985	ENOG4107RPQ	ABC transporter
AXH35_11000	ENOG4105C6K	Malic enzyme
AXH35_11020	ENOG41086YM	Acylphosphatase
AXH35_11025	ENOG4105CD5	CoA-binding domain protein
AXH35_11030	ENOG4105D8K	carboxyl transferase
AXH35_11040	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
AXH35_11045	ENOG4105D9Q	decarboxylase (Beta subunit)
AXH35_11060	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXH35_11085	ENOG4105CTQ	phosphohexokinase
AXH35_11125	ENOG4105K78	MarR family Transcriptional regulator
AXH35_11135	ENOG4105C59	p-type ATPase
AXH35_11145	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AXH35_11150	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
AXH35_11200	ENOG4105F5W	AtP-binding protein
AXH35_11230	ENOG4105F5W	AtP-binding protein
AXH35_11250	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AXH35_11260	ENOG4108J59	Extracellular solute-binding protein, family 5
AXH35_11265	ENOG4108JQ6	ABC transporter
AXH35_11270	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AXH35_11275	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AXH35_11290	ENOG4105F4R	Transcriptional regulator mode
AXH35_11315	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
AXH35_11320	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
AXH35_11325	ENOG4108SQ9	flavin reductase domain protein, FMN-binding
AXH35_11345	ENOG4108IUE	nitrate reductase beta subunit
AXH35_11365	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AXH35_11375	ENOG4108ZAF	Molybdopterin
AXH35_11385	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AXH35_11390	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AXH35_11395	ENOG4108VW9	Membrane
AXH35_11400	ENOG4105DWF	phosphomethylpyrimidine kinase
AXH35_11405	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AXH35_11410	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
AXH35_11430	ENOG4105C2J	ABC transporter
AXH35_11445	ENOG41068JE	domain protein
AXH35_11460	ENOG4105DZW	Dipeptidase
AXH35_11470	ENOG4105C26	Dehydrogenase
AXH35_11480	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_11485	ENOG4105D2H	Uronic isomerase
AXH35_11490	ENOG4105DEI	Mannitol dehydrogenase
AXH35_11495	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
AXH35_11515	ENOG4105DTQ	mandelate racemase muconate lactonizing
AXH35_11535	ENOG4105KT7	mgtC SapB transporter
AXH35_11545	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_11550	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
AXH35_11555	ENOG4105BZ7	extracellular solute-binding protein family 1
AXH35_11560	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
AXH35_11610	ENOG4105C8Y	Acetylornithine aminotransferase
AXH35_11620	ENOG4105EIP	mannose-6-phosphate isomerase
AXH35_11625	ENOG4105D7K	pfkb domain protein
AXH35_11630	ENOG4108UHU	Aldolase
AXH35_11635	ENOG4108FUF	Transcriptional regulator, IclR family
AXH35_11640	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_11645	ENOG4107QZW	Altronate oxidoreductase
AXH35_11650	ENOG4105CTX	dehydratase
AXH35_11655	ENOG4105D2H	Uronic isomerase
AXH35_11730	ENOG4105CT4	transporter
AXH35_11765	ENOG4105EQN	UPF0261 protein
AXH35_11770	ENOG41073TP	transcriptional regulator
AXH35_11785	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_11790	ENOG4105D1H	recombination factor protein RarA
AXH35_11810	ENOG4105DKW	ABC transporter
AXH35_11820	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AXH35_11830	ENOG4107T5V	SNARE associated Golgi
AXH35_11835	ENOG4105CPQ	Dehydrogenase
AXH35_11850	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AXH35_11880	ENOG4105C37	(CBS) domain
AXH35_11890	ENOG4108Z7F	N-acetyltransferase
AXH35_11910	ENOG4105F95	Monooxygenase
AXH35_11995	ENOG4107T8Q	Glycosyl transferase (Group 1
AXH35_12000	ENOG4107T8Q	Glycosyl transferase (Group 1
AXH35_12040	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AXH35_12070	ENOG4105DM4	PTS System
AXH35_12075	ENOG4105DE4	1-phosphofructokinase
AXH35_12080	ENOG4105E98	transcriptional regulator DeoR family
AXH35_12090	ENOG4108Q1T	ABC transporter
AXH35_12095	ENOG4107UBR	Extracellular solute-binding protein family 3
AXH35_12100	ENOG4105CDA	abc transporter atp-binding protein
AXH35_12105	ENOG4108IJ1	Dehydrogenase
AXH35_12115	ENOG4107QPH	glycogen) synthase
AXH35_12120	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AXH35_12155	ENOG4105KHC	sulfurtransferase
AXH35_12170	ENOG4105CQ7	ATP-dependent helicase
AXH35_12185	ENOG4108VX5	3-methyladenine DNA glycosylase
AXH35_12205	ENOG4108V8F	Transcriptional regulator, MarR family
AXH35_12210	ENOG4108V06	Glutathione peroxidase
AXH35_12215	ENOG4105C3M	thioredoxin reductase
AXH35_12220	ENOG4105K63	Thioredoxin
AXH35_12225	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AXH35_12230	ENOG4105CDU	Replicative dna helicase
AXH35_12235	ENOG4105VPX	protein, conserved in bacteria
AXH35_12250	ENOG4105K6T	rare lipoprotein A
AXH35_12300	ENOG4107YJ4	chain length determinant protein
AXH35_12325	ENOG4105CG5	Glycosyl transferase (Group 1
AXH35_12355	ENOG4105D2T	synthase
AXH35_12360	ENOG4105F0R	Cytidylyltransferase
AXH35_12370	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AXH35_12390	ENOG41073TP	transcriptional regulator
AXH35_12395	ENOG4105DAA	L-lactate
AXH35_12400	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AXH35_12410	ENOG41080R8	Conserved Protein
AXH35_12420	ENOG4105BZ1	(ABC) transporter
AXH35_12425	ENOG4108JJ9	ABC, transporter
AXH35_12430	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AXH35_12435	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AXH35_12470	ENOG4108JB8	alcohol dehydrogenase
AXH35_12480	ENOG4105XN3	extracellular solute-binding protein family 1
AXH35_12485	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
AXH35_12495	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_12510	ENOG4105KBX	Transcriptional regulator, TetR family
AXH35_12515	ENOG4107VXZ	Hydrolase
AXH35_12530	ENOG4105C5B	carbamate kinase
AXH35_12540	ENOG4107REC	cytoplasmic protein
AXH35_12545	ENOG4107R1Q	Membrane protein FdrA
AXH35_12550	ENOG4107YCY	Transcriptional regulator
AXH35_12570	ENOG4105C5R	Aminotransferase
AXH35_12580	ENOG4105CK2	sodium dicarboxylate symporter
AXH35_12585	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
AXH35_12595	ENOG4105K8R	UPF0145 protein
AXH35_12600	ENOG4105CRK	lysyL-tRNA synthetase
AXH35_12605	ENOG4105ZJT	Cell division protein CrgA
AXH35_12625	ENOG4105CJN	penicillin-binding protein
AXH35_12640	ENOG4105HZM	Fha domain containing protein
AXH35_12645	ENOG4105TV9	FHA Domain-Containing protein
AXH35_12655	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AXH35_12660	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AXH35_12675	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AXH35_12680	ENOG4105D3Q	Sugar transferase
AXH35_12695	ENOG4108KGH	TRANSCRIPTIONal
AXH35_12700	ENOG4105D3Q	Sugar transferase
AXH35_12705	ENOG4107YJ4	chain length determinant protein
AXH35_12710	ENOG4107WAU	Protein tyrosine phosphatase
AXH35_12720	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
AXH35_12730	ENOG4105F5W	AtP-binding protein
AXH35_12780	ENOG4105CSH	Transporter
AXH35_12800	ENOG4105C85	amino acid
AXH35_12805	ENOG4108X07	Tetr family transcriptional regulator
AXH35_12810	ENOG4105CIG	ABC transporter
AXH35_12855	ENOG41087ID	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AXH35_12860	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AXH35_12885	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXH35_12895	ENOG410667J	hydrolase
AXH35_12900	ENOG4108HCJ	Hydrolase
AXH35_12905	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AXH35_12925	ENOG4105CFH	Aspartokinase
AXH35_12945	ENOG4105D94	Major Facilitator Superfamily
AXH35_12950	ENOG4107RSM	transcriptional regulator
AXH35_12970	ENOG41085J0	Protein CrcB homolog
AXH35_12975	ENOG41083TI	Protein CrcB homolog
AXH35_12985	ENOG4108FN7	Aldo keto reductase
AXH35_13005	ENOG4108V1U	phospholipid-binding protein
AXH35_13015	ENOG4105CQR	helicase
AXH35_13025	ENOG4107QP8	phosphohexose isomerase
AXH35_13040	ENOG4105IE8	Alpha-ketoglutarate permease
AXH35_13045	ENOG4105CV8	reductase
AXH35_13050	ENOG4105C75	arginyL-tRNA synthetase
AXH35_13070	ENOG4105C54	Major Facilitator superfamily
AXH35_13085	ENOG4105C26	Dehydrogenase
AXH35_13090	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
AXH35_13095	ENOG4105DET	Rhamnulokinase
AXH35_13100	ENOG4105C9F	isomerase
AXH35_13110	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
AXH35_13115	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_13155	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_13180	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AXH35_13185	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AXH35_13190	ENOG4108JQ6	ABC transporter
AXH35_13195	ENOG4108IJ0	Aspartate ammonia-lyase
AXH35_13245	ENOG4108JQ7	(ABC) transporter
AXH35_13270	ENOG4105EJ2	Transcriptional regulator
AXH35_13285	ENOG4105DSB	aldose 1-epimerase
AXH35_13290	ENOG4105EAC	phosphoserine phosphatase
AXH35_13295	ENOG4107RNR	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA (By similarity)
AXH35_13300	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AXH35_13305	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AXH35_13320	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AXH35_13325	ENOG4105BZU	Histidine kinase
AXH35_13330	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AXH35_13345	ENOG4105CFG	Acts as a chaperone (By similarity)
AXH35_13350	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AXH35_13355	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AXH35_13360	ENOG4105KNI	merR family transcriptional Regulator
AXH35_13365	ENOG4105CPQ	Dehydrogenase
AXH35_13370	ENOG4107FQX	Alpha-acetolactate decarboxylase
AXH35_13375	ENOG4107WGA	YidE YbjL
AXH35_13380	ENOG4105C85	amino acid
AXH35_13390	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXH35_13395	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AXH35_13405	ENOG4105WH1	Two component transcriptional regulator luxr family
AXH35_13410	ENOG4105BZU	Histidine kinase
AXH35_13425	ENOG4105WYW	fructose-bisphosphate aldolase
AXH35_13430	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_13440	ENOG4107RBJ	symporter
AXH35_13455	ENOG4105DRS	transport system, permease
AXH35_13465	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AXH35_13470	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
AXH35_13475	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AXH35_13485	ENOG4105EDK	PfkB domain protein
AXH35_13490	ENOG4105E98	transcriptional regulator DeoR family
AXH35_13495	ENOG4105F8D	glycoside hydrolase family 4
AXH35_13510	ENOG4105ECB	domain protein
AXH35_13525	ENOG4105ECR	NmrA family
AXH35_13540	ENOG4105DRS	transport system, permease
AXH35_13545	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
AXH35_13550	ENOG4107FKK	extracellular solute-binding protein family 1
AXH35_13555	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_13560	ENOG4105DZR	Type I site-specific deoxyribonuclease
AXH35_13570	ENOG4105CVR	type I restriction-modification system
AXH35_13595	ENOG4105K5B	UPF0225 protein
AXH35_13600	ENOG4108IJ7	Glycine betaine
AXH35_13605	ENOG4108HQS	Glycine betaine
AXH35_13625	ENOG4105E90	ABC transporter
AXH35_13630	ENOG4108IJ8	ABC transporter
AXH35_13635	ENOG4105E90	ABC transporter
AXH35_13645	ENOG4105C26	Dehydrogenase
AXH35_13650	ENOG4105CHM	Aminotransferase
AXH35_13675	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AXH35_13695	ENOG4105E2K	Glycosyl transferase (Group 1
AXH35_13730	ENOG4107YJ4	chain length determinant protein
AXH35_13750	ENOG4105DQR	SNARE associated Golgi
AXH35_13765	ENOG4107RCW	fructose-bisphosphate aldolase
AXH35_13770	ENOG4107QSA	Oxaloacetate decarboxylase
AXH35_13775	ENOG4107QX3	carboxylase
AXH35_13780	ENOG4107QX3	carboxylase
AXH35_13785	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
AXH35_13795	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AXH35_13800	ENOG410849S	phosphocarrier protein (HPr)
AXH35_13805	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AXH35_13810	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AXH35_13815	ENOG4105BZU	Histidine kinase
AXH35_13830	ENOG4108VJ1	Transcriptional regulator (CarD family
AXH35_13835	ENOG41082GB	PTS system galactitol-specific transporter subunit IIA
AXH35_13845	ENOG4105DT3	PTS system, galactitol-specific IIc component
AXH35_13855	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AXH35_13870	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AXH35_13875	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AXH35_13895	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AXH35_13900	ENOG4105EQ0	Major Facilitator superfamily
AXH35_13915	ENOG4105C8N	cysteinyl-tRNA synthetase
AXH35_13930	ENOG4105C28	cystathionine
AXH35_13980	ENOG4105F5W	AtP-binding protein
AXH35_14005	ENOG4107URF	beta-phospho-glucomutase
AXH35_14015	ENOG4105EJQ	L-serine dehydratase
AXH35_14020	ENOG4105DKQ	ROK family
AXH35_14035	ENOG4105DRS	transport system, permease
AXH35_14040	ENOG4105CPQ	Dehydrogenase
AXH35_14045	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AXH35_14055	ENOG4108UVJ	appr-1-p processing domain protein
AXH35_14060	ENOG4108M15	ABC transporter
AXH35_14070	ENOG4108ZGX	Histidine kinase
AXH35_14075	ENOG4108S01	response regulator
AXH35_14085	ENOG4105CVJ	phosphoglycerate mutase
AXH35_14100	ENOG4105CJ1	ABC, transporter
AXH35_14105	ENOG4105BZU	Histidine kinase
AXH35_14110	ENOG4105WH1	Two component transcriptional regulator luxr family
AXH35_14115	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AXH35_14120	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AXH35_14130	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
AXH35_14135	ENOG4105E4R	Precorrin-3B C17-methyltransferase
AXH35_14140	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AXH35_14155	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
AXH35_14165	ENOG4108V4M	Cobalt abc transporter
AXH35_14170	ENOG4108JJB	ABC transporter
AXH35_14175	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
AXH35_14180	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AXH35_14185	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AXH35_14190	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AXH35_14200	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AXH35_14205	ENOG4108YZT	Adenosylcobinamide kinase
AXH35_14230	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AXH35_14235	ENOG4105EIP	mannose-6-phosphate isomerase
AXH35_14245	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AXH35_14365	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AXH35_14560	ENOG4107T65	Integrase
AXH35_14575	ENOG4106N3A	copper homeostasis protein cutc
AXH35_14595	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AXH35_14600	ENOG4105VEQ	Cold shock protein
AXH35_14615	ENOG4105C7N	Xanthine uracil vitamin C permease
AXH35_14635	ENOG4105CE4	GlcNAc 6-P deacetylase
AXH35_14640	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
AXH35_14645	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AXH35_14655	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AXH35_14660	ENOG4105D7K	pfkb domain protein
AXH35_14670	ENOG4105DH8	myo-inositol catabolism
AXH35_14675	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
AXH35_14685	ENOG41060NJ	transcriptional regulator
AXH35_14690	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AXH35_14695	ENOG4105C54	Major Facilitator superfamily
AXH35_14720	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AXH35_14735	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AXH35_14850	ENOG4105C0D	helicase
AXH35_14870	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
AXH35_14875	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AXH35_14910	ENOG4108Z0Z	intracellular protease Pfpi family
AXH35_14970	ENOG4105E7W	lamb ycsf family protein
AXH35_14975	ENOG4105P4J	Allophanate hydrolase, subunit 1
AXH35_14985	ENOG4105C2W	permease
AXH35_15000	ENOG4105F8V	Hydrolase, tatD family
AXH35_15005	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AXH35_15010	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AXH35_15015	ENOG41082F9	transcriptional regulator
AXH35_15020	ENOG4105U5Y	Transcriptional regulator
AXH35_15030	ENOG4107U1N	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AXH35_15035	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AXH35_15040	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AXH35_15045	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AXH35_15065	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AXH35_15095	ENOG4105EZR	dyp-type peroxidase family protein
AXH35_15100	ENOG4105C0H	protease
AXH35_15150	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AXH35_15155	ENOG41084BS	50S ribosomal protein L35
AXH35_15160	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AXH35_15165	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
AXH35_15175	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AXH35_15180	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AXH35_15185	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AXH35_15200	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AXH35_15235	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AXH35_15240	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AXH35_15255	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AXH35_15270	ENOG4105C7Z	Conserved Protein
AXH35_15280	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AXH35_15290	ENOG4108IAB	Phoh family
AXH35_15300	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AXH35_15305	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AXH35_15310	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AXH35_15320	ENOG4105DFM	M18 family aminopeptidase
AXH35_15325	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AXH35_15345	ENOG4105C3G	gtp-binding protein
AXH35_15430	ENOG41065RQ	ADP-ribosylation crystallin J1
AXH35_15445	ENOG4105BZ1	(ABC) transporter
AXH35_15450	ENOG4108ZM9	phosphoglycerate mutase
AXH35_15470	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AXH35_15475	ENOG4108RWI	nicotinamidase
AXH35_15505	ENOG4105CSH	Transporter
AXH35_15510	ENOG4105CSH	Transporter
AXH35_15535	ENOG4105RH4	Glycine cleavage system transcriptional repressor
AXH35_15555	ENOG4108IQI	permease
AXH35_15575	ENOG4105CMN	Methylmalonyl-coA mutase
AXH35_15580	ENOG4105D5P	Methylmalonyl-coA mutase
AXH35_15590	ENOG410848D	S4 domain protein YaaA
AXH35_15605	ENOG4105CDA	abc transporter atp-binding protein
AXH35_15610	ENOG4105E5Q	amino acid AbC transporter
AXH35_15640	ENOG4105CC5	ABC transporter
AXH35_15645	ENOG4105DIK	(ABC) transporter
AXH35_15665	ENOG4105C26	Dehydrogenase
AXH35_15670	ENOG4105CPQ	Dehydrogenase
AXH35_15675	ENOG4105CMT	Dihydroxyacetone kinase
AXH35_15680	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AXH35_15685	ENOG4105E98	transcriptional regulator DeoR family
AXH35_15690	ENOG4107YVI	ribose 5-phosphate isomerase
AXH35_15700	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AXH35_15710	ENOG4105D49	3-dehydroquinate synthase
AXH35_15715	ENOG4105EF1	ribulokinase
AXH35_15745	ENOG4107Y80	Major Facilitator superfamily
AXH35_15750	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AXH35_15755	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AXH35_15760	ENOG4107S1E	Beta-lactamase
AXH35_15765	ENOG4107RBI	VanW family
AXH35_15770	ENOG4108Z4U	Ferredoxin
AXH35_15790	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AXH35_15800	ENOG4108URH	decarboxylase
AXH35_15810	ENOG4107QPH	glycogen) synthase
AXH35_15815	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AXH35_15840	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AXH35_15845	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AXH35_15880	ENOG4107T6F	Xaa-Pro aminopeptidase
AXH35_15895	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AXH35_15900	ENOG4105CUB	amino acid
AXH35_15920	ENOG4105D7N	magnesium and cobalt transport protein CorA
AXH35_15945	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AXH35_15955	ENOG4105EGD	dinuclear metal center protein, YbgI family
AXH35_15970	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AXH35_15980	ENOG4105C5F	glutamine synthetase
AXH35_16005	ENOG4105CJW	magnesium transporter
AXH35_16010	ENOG4105C5H	ABC transporter
AXH35_16020	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AXH35_16035	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AXH35_16080	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AXH35_16085	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AXH35_16090	ENOG4105MCD	Part of cytochrome c oxidase, its function is
AXH35_16105	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AXH35_16110	ENOG4107EUI	c reductase, iron-sulfur
AXH35_16115	ENOG4107UDY	cytochrome C
AXH35_16120	ENOG4105CCU	oxidase (Subunit III)
AXH35_16130	ENOG4107S1N	anthranilate phosphoribosyltransferase
AXH35_16175	ENOG4105DKQ	ROK family
AXH35_16195	ENOG4105WH1	Two component transcriptional regulator luxr family
AXH35_16200	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AXH35_16225	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AXH35_16235	ENOG4105SYT	Methylenetetrahydrofolate reductase
AXH35_16240	ENOG4105C4R	Atp-dependent dna helicase
AXH35_16260	ENOG4105D7T	ABC transporter
AXH35_16265	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AXH35_16275	ENOG4108J5G	6-phosphogluconate dehydrogenase
AXH35_16280	ENOG4105C6Z	Gluconate
AXH35_16285	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AXH35_16305	ENOG4105CJ1	ABC, transporter
AXH35_16310	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AXH35_16315	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AXH35_16320	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AXH35_16330	ENOG4105F8C	transglutaminase domain-containing protein
AXH35_16340	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AXH35_16345	ENOG4108V6E	Cell division protein mraZ
AXH35_16350	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AXH35_16360	ENOG4105CJN	penicillin-binding protein
AXH35_16375	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AXH35_16380	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AXH35_16385	ENOG4105CNI	cell division protein FtsW
AXH35_16390	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AXH35_16395	ENOG4105DFU	Cell wall formation (By similarity)
AXH35_16400	ENOG4105ME9	cell division protein FtsQ
AXH35_16405	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AXH35_16410	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AXH35_16415	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
AXH35_16430	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AXH35_16445	ENOG4105CA9	Pyruvate kinase
AXH35_16460	ENOG4105KA0	thioesterase Superfamily protein
AXH35_16485	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AXH35_16490	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AXH35_16505	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AXH35_16520	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AXH35_16540	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AXH35_16545	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AXH35_16550	ENOG4105CHW	UPF0052 protein
AXH35_16555	ENOG4105CIE	May be required for sporulation (By similarity)
AXH35_16560	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AXH35_16565	ENOG4105BZA	Phosphoglycerate kinase
AXH35_16570	ENOG4105CP7	Triose-phosphate isomerase
AXH35_16585	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AXH35_16595	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AXH35_16605	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AXH35_16615	ENOG4105C03	ribonuclease
AXH35_16620	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AXH35_16625	ENOG4105K46	50S ribosomal protein l27
AXH35_16635	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AXH35_16640	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AXH35_16645	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AXH35_16650	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AXH35_16765	ENOG4105E4C	Lytic transglycosylase catalytic
AXH35_16830	ENOG41082EK	Restriction modification system DNA (Specificity
AXH35_16875	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_16925	ENOG4105CH6	catalase
AXH35_16930	ENOG4105ETE	Transcriptional regulator (LacI family
AXH35_16935	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AXH35_16940	ENOG4105C54	Major Facilitator superfamily
AXH35_16950	ENOG4105CPC	Aldo Keto reductase
AXH35_16960	ENOG4105C59	p-type ATPase
AXH35_16975	ENOG4107R7Y	intracellular protease Pfpi family