locus-tag	class	description
BWX38_00010	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWX38_00015	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWX38_00020	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWX38_00025	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BWX38_00040	ENOG4105F8C	transglutaminase domain-containing protein
BWX38_00050	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BWX38_00055	ENOG4108V6E	Cell division protein mraZ
BWX38_00060	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
BWX38_00070	ENOG4105CJN	penicillin-binding protein
BWX38_00085	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BWX38_00090	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
BWX38_00095	ENOG4105CNI	cell division protein FtsW
BWX38_00100	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
BWX38_00105	ENOG4105DFU	Cell wall formation (By similarity)
BWX38_00110	ENOG4105ME9	cell division protein FtsQ
BWX38_00115	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BWX38_00120	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
BWX38_00125	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
BWX38_00140	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BWX38_00155	ENOG4105CA9	Pyruvate kinase
BWX38_00170	ENOG4105KA0	thioesterase Superfamily protein
BWX38_00200	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
BWX38_00205	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
BWX38_00220	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BWX38_00235	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BWX38_00255	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
BWX38_00260	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
BWX38_00265	ENOG4105CHW	UPF0052 protein
BWX38_00270	ENOG4105CIE	May be required for sporulation (By similarity)
BWX38_00275	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BWX38_00280	ENOG4105BZA	Phosphoglycerate kinase
BWX38_00285	ENOG4105CP7	Triose-phosphate isomerase
BWX38_00300	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
BWX38_00310	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BWX38_00320	ENOG4105D17	glycoside hydrolase, family 3 domain protein
BWX38_00330	ENOG4105C03	ribonuclease
BWX38_00335	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
BWX38_00340	ENOG4105K46	50S ribosomal protein l27
BWX38_00350	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BWX38_00355	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
BWX38_00360	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
BWX38_00365	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
BWX38_00410	ENOG4105EW9	transcriptional regulator AsnC family
BWX38_00520	ENOG4107Y2X	deaminase
BWX38_00530	ENOG4107ZXU	DSBA oxidoreductase
BWX38_00545	ENOG4105C8T	Leucyl-tRNA synthetase
BWX38_00555	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
BWX38_00560	ENOG4105F8X	type iii restriction
BWX38_00570	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
BWX38_00575	ENOG4107QW3	Sucrose phosphorylase
BWX38_00580	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
BWX38_00600	ENOG4107TCW	O-succinylbenzoate synthase
BWX38_00605	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
BWX38_00610	ENOG4105E4F	Isochorismate synthase
BWX38_00620	ENOG4107SIQ	Naphthoate synthase
BWX38_00630	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BWX38_00635	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BWX38_00660	ENOG4105CSH	Transporter
BWX38_00670	ENOG4105DRS	transport system, permease
BWX38_00695	ENOG4105ECY	inositol monophosphatase
BWX38_00705	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
BWX38_00710	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BWX38_00720	ENOG4105CPQ	Dehydrogenase
BWX38_00725	ENOG4105CTS	PTS system mannitol-specific
BWX38_00735	ENOG4105C9U	ATP-dependent DNA helicase RecQ
BWX38_00740	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BWX38_00745	ENOG4107AQZ	Membrane
BWX38_00750	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
BWX38_00760	ENOG4105WH1	Two component transcriptional regulator luxr family
BWX38_00765	ENOG4108IUX	(ABC) transporter
BWX38_00805	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BWX38_00825	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
BWX38_00835	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BWX38_00845	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BWX38_00850	ENOG4105CT1	(ABC) transporter
BWX38_00855	ENOG4105E5Q	amino acid AbC transporter
BWX38_00860	ENOG4105DRP	amino acid AbC transporter
BWX38_00870	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BWX38_00880	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BWX38_00885	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
BWX38_00890	ENOG4105CPQ	Dehydrogenase
BWX38_00925	ENOG41090R7	Ferric uptake
BWX38_00935	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
BWX38_00945	ENOG4108IYU	L-aspartate oxidase
BWX38_00950	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
BWX38_00960	ENOG4105CVK	Glutamate decarboxylase
BWX38_01000	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
BWX38_01005	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
BWX38_01010	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BWX38_01035	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
BWX38_01055	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BWX38_01065	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
BWX38_01075	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
BWX38_01085	ENOG4108QVN	serine threonine protein kinase
BWX38_01095	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BWX38_01125	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BWX38_01135	ENOG4107QVM	von Willebrand factor, type A
BWX38_01145	ENOG4105DFA	alanine racemase domain protein
BWX38_01160	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
BWX38_01175	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
BWX38_01190	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
BWX38_01200	ENOG4105CPC	Aldo Keto reductase
BWX38_01215	ENOG4105CD3	dihydroorotase
BWX38_01220	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
BWX38_01225	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
BWX38_01230	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
BWX38_01235	ENOG4107TYT	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
BWX38_01240	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BWX38_01245	ENOG4107T52	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BWX38_01275	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
BWX38_01285	ENOG4105CEV	competence damage-inducible protein
BWX38_01295	ENOG4105E98	transcriptional regulator DeoR family
BWX38_01305	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BWX38_01310	ENOG4105KC9	Modulates RecA activity (By similarity)
BWX38_01315	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
BWX38_01325	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BWX38_01335	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
BWX38_01340	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
BWX38_01345	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BWX38_01360	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
BWX38_01365	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BWX38_01370	ENOG4105DHP	deoxycytidine triphosphate deaminase
BWX38_01390	ENOG4105CQ7	ATP-dependent helicase
BWX38_01400	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
BWX38_01415	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BWX38_01435	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BWX38_01445	ENOG4105EPD	Oligopeptide transporter, Opt family
BWX38_01480	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
BWX38_01500	ENOG4107VEG	TrkA-N domain protein
BWX38_01505	ENOG4105C0X	amino acid
BWX38_01510	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BWX38_01520	ENOG4107QM5	aconitate hydratase
BWX38_01525	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BWX38_01540	ENOG4105E0X	reductase
BWX38_01545	ENOG4105CSR	polyphosphate kinase 2
BWX38_01575	ENOG4108ZJ4	polysaccharide deacetylase
BWX38_01605	ENOG4105DQ4	alcohol dehydrogenase
BWX38_01610	ENOG4105C22	threonyL-tRNA synthetase
BWX38_01625	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
BWX38_01630	ENOG4105E2K	Glycosyl transferase (Group 1
BWX38_01655	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BWX38_01660	ENOG4108UW8	fha domain-containing protein
BWX38_01680	ENOG4107H3J	ribonuclease
BWX38_01685	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
BWX38_01695	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
BWX38_01700	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
BWX38_01705	ENOG4107TE5	Lipid kinase
BWX38_01710	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
BWX38_01715	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BWX38_01730	ENOG4105CFG	Acts as a chaperone (By similarity)
BWX38_01750	ENOG4107QZ7	Cellulose synthase catalytic subunit
BWX38_01765	ENOG4105CUB	amino acid
BWX38_01780	ENOG4105D22	carbon starvation protein
BWX38_01790	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
BWX38_01795	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
BWX38_01805	ENOG4105Q70	
BWX38_01810	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
BWX38_01815	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
BWX38_01825	ENOG4105DWV	Homoserine O-trans-acetylase
BWX38_01830	ENOG4105DWV	Homoserine O-trans-acetylase
BWX38_01835	ENOG4105CYC	Transferase
BWX38_01860	ENOG4105DJ2	Major Facilitator Superfamily
BWX38_01950	ENOG4105DNP	FAD linked oxidase domain protein
BWX38_01960	ENOG4105C8Y	Acetylornithine aminotransferase
BWX38_01980	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BWX38_01990	ENOG4107S1Q	Phosphatase
BWX38_02020	ENOG4105DZR	Type I site-specific deoxyribonuclease
BWX38_02060	ENOG4108Z9K	Osmotically inducible protein
BWX38_02070	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BWX38_02075	ENOG4105CAT	Cytidine monophosphate kinase
BWX38_02085	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
BWX38_02090	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
BWX38_02105	ENOG4105C3R	Methionine synthase
BWX38_02115	ENOG4105DJV	ribulose-phosphate 3-epimerase
BWX38_02125	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
BWX38_02160	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
BWX38_02165	ENOG4107QRT	dEAD DEAH box helicase
BWX38_02170	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
BWX38_02180	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
BWX38_02185	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
BWX38_02195	ENOG410803B	Involved in the transcription termination process (By similarity)
BWX38_02200	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
BWX38_02210	ENOG4105D49	3-dehydroquinate synthase
BWX38_02215	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BWX38_02220	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
BWX38_02225	ENOG4105E2X	shikimate dehydrogenase
BWX38_02235	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
BWX38_02240	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BWX38_02275	ENOG4105C9M	aspartyl-trna synthetase
BWX38_02290	ENOG4107MVR	Transcriptional regulator
BWX38_02295	ENOG4105CIZ	coA-substrate-specific enzyme activase
BWX38_02300	ENOG4105CUT	histidyl-tRNA synthetase
BWX38_02305	ENOG4105C5X	domain protein
BWX38_02310	ENOG4105C99	atpase involved in dna repair
BWX38_02315	ENOG4105D98	threonine synthase
BWX38_02320	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
BWX38_02330	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BWX38_02335	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BWX38_02350	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BWX38_02355	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
BWX38_02360	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
BWX38_02365	ENOG4105CDY	transcriptional regulatory protein
BWX38_02370	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
BWX38_02375	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
BWX38_02380	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
BWX38_02385	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BWX38_02390	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
BWX38_02425	ENOG4105DRS	transport system, permease
BWX38_02435	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_02445	ENOG4105CBC	glutamate synthase
BWX38_02450	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
BWX38_02455	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
BWX38_02465	ENOG4105DK0	Indole-3-glycerol phosphate synthase
BWX38_02480	ENOG4105CRQ	synthase (Component I)
BWX38_02485	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
BWX38_02500	ENOG4105C2W	permease
BWX38_02510	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BWX38_02515	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BWX38_02520	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BWX38_02545	ENOG4108IY8	ABC, transporter
BWX38_02560	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BWX38_02585	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
BWX38_02590	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
BWX38_02595	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
BWX38_02610	ENOG4107UVD	Beta-phosphoglucomutase family hydrolase
BWX38_02620	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
BWX38_02645	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
BWX38_02675	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BWX38_02680	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
BWX38_02685	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
BWX38_02690	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
BWX38_02695	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
BWX38_02700	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
BWX38_02705	ENOG4106DE0	ATP synthase
BWX38_02710	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
BWX38_02725	ENOG4105D7W	serine acetyltransferase
BWX38_02735	ENOG4105CAQ	asparagine synthetase
BWX38_02750	ENOG4105CEY	Amp-dependent synthetase and ligase
BWX38_02835	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BWX38_02840	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
BWX38_02845	ENOG4105VFB	Binds the 23S rRNA (By similarity)
BWX38_02855	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
BWX38_02860	ENOG4105D6E	homoserine dehydrogenase
BWX38_02865	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
BWX38_02875	ENOG4108URH	decarboxylase
BWX38_02885	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
BWX38_02910	ENOG4105EMN	RNA polymerase sigma factor
BWX38_02920	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
BWX38_02925	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
BWX38_02935	ENOG4107TK4	histidinol-phosphate phosphatase
BWX38_02940	ENOG4108JQ1	Dehydrogenase
BWX38_02945	ENOG4108JQ6	ABC transporter
BWX38_02955	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BWX38_02965	ENOG4105DEF	Extracellular solute-binding protein, family 5
BWX38_02985	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BWX38_02995	ENOG4105DJZ	UPF0182 protein
BWX38_03005	ENOG41063PX	domain protein
BWX38_03030	ENOG4105DSY	exodeoxyribonuclease V, gamma
BWX38_03035	ENOG4107QKA	exodeoxyribonuclease V beta
BWX38_03040	ENOG4105C7H	Helicase, RecD TraA family
BWX38_03055	ENOG4105C4R	Atp-dependent dna helicase
BWX38_03060	ENOG4105VEQ	Cold shock protein
BWX38_03085	ENOG4105C31	Tryptophanyl-tRNA synthetase
BWX38_03095	ENOG4105DB7	PHP domain protein
BWX38_03115	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
BWX38_03125	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
BWX38_03135	ENOG4105G3P	Lipoprotein lpqB
BWX38_03140	ENOG4105BZU	Histidine kinase
BWX38_03145	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BWX38_03150	ENOG4108UJU	UPF0301 protein
BWX38_03165	ENOG4105CH7	arginosuccinase
BWX38_03170	ENOG4105DBV	ornithine carbamoyltransferase
BWX38_03175	ENOG4105C8Y	Acetylornithine aminotransferase
BWX38_03180	ENOG4105CAS	nag kinase
BWX38_03185	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
BWX38_03195	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
BWX38_03200	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
BWX38_03205	ENOG4105CAK	Cell division ATP-binding protein ftsE
BWX38_03210	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
BWX38_03225	ENOG4105KAF	membrAne
BWX38_03235	ENOG4107QZI	cell division protein FtsK
BWX38_03255	ENOG4105CPF	Cell wall formation (By similarity)
BWX38_03265	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BWX38_03270	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
BWX38_03275	ENOG41069M3	Transcriptional regulator
BWX38_03295	ENOG4105ERH	Fumarylacetoacetate hydrolase
BWX38_03305	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
BWX38_03310	ENOG4105CM2	brancheD-chain amino acid aminotransferase
BWX38_03335	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
BWX38_03340	ENOG4108ZP8	Acetolactate synthase small subunit
BWX38_03350	ENOG4105K59	histidine triad (HIT) protein
BWX38_03355	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
BWX38_03365	ENOG4107TE5	Lipid kinase
BWX38_03375	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
BWX38_03395	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
BWX38_03430	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BWX38_03435	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
BWX38_03440	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BWX38_03455	ENOG4108JJB	ABC transporter
BWX38_03460	ENOG4105VKD	bioY protein
BWX38_03465	ENOG4105DSU	hydrolase
BWX38_03500	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
BWX38_03505	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
BWX38_03520	ENOG4105CPC	Aldo Keto reductase
BWX38_03530	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BWX38_03555	ENOG4108KQ5	Integrase catalytic subunit
BWX38_03570	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_03575	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
BWX38_03585	ENOG4107QNK	)-transporter
BWX38_03595	ENOG4105BZ7	extracellular solute-binding protein family 1
BWX38_03605	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
BWX38_03615	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_03620	ENOG4105DRS	transport system, permease
BWX38_03650	ENOG4105C0P	Mg chelatase subunit ChlI
BWX38_03655	ENOG41080R2	UPF0102 protein
BWX38_03665	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BWX38_03670	ENOG4107QYR	Signal peptidase i
BWX38_03675	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
BWX38_03680	ENOG4105E33	succinate dehydrogenase
BWX38_03695	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
BWX38_03700	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
BWX38_03705	ENOG41082KU	UPF0109 protein
BWX38_03710	ENOG4105K5M	30s ribosomal protein S16
BWX38_03745	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
BWX38_03790	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
BWX38_03795	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
BWX38_03800	ENOG41084BZ	50S ribosomal protein L32
BWX38_03810	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
BWX38_03815	ENOG4106H78	methyltransferase
BWX38_03835	ENOG4105VB9	50S ribosomal protein l28
BWX38_03840	ENOG4105CN5	Metallo-Beta-Lactamase
BWX38_03850	ENOG4105C7K	acetolactate synthase
BWX38_03860	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
BWX38_03865	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BWX38_03870	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BWX38_03890	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BWX38_03905	ENOG410787A	Pts system, glucitol sorbitol-specific
BWX38_03910	ENOG4105DZY	Pts system, glucitol sorbitol-specific
BWX38_03915	ENOG4105VI0	Pts system, glucitol sorbitol-specific
BWX38_03925	ENOG4108MDK	Dehydrogenase
BWX38_03930	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
BWX38_03935	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
BWX38_03940	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
BWX38_03955	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
BWX38_03975	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BWX38_04015	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
BWX38_04020	ENOG4105DZP	Membrane-associated zinc metalloprotease
BWX38_04030	ENOG4105D82	Glutamate dehydrogenase
BWX38_04035	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BWX38_04040	ENOG4105KNE	Phosphatidate cytidylyltransferase
BWX38_04045	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
BWX38_04050	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BWX38_04055	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
BWX38_04060	ENOG4105CE9	30S ribosomal protein S2
BWX38_04070	ENOG4108KDT	Molybdate metabolism regulator
BWX38_04075	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
BWX38_04085	ENOG4105DEG	Vwa containing coxe family protein
BWX38_04100	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BWX38_04110	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
BWX38_04135	ENOG4105DHU	Bile acid
BWX38_04150	ENOG4105DKW	ABC transporter
BWX38_04155	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
BWX38_04165	ENOG4108IJ0	Aspartate ammonia-lyase
BWX38_04180	ENOG4105CHR	reductase
BWX38_04195	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BWX38_04210	ENOG4105C5H	ABC transporter
BWX38_04255	ENOG4108UNV	SUF system FeS assembly protein, NifU family
BWX38_04260	ENOG4105C9B	Cysteine desulfurase
BWX38_04265	ENOG4105C3K	feS assembly ATPase SufC
BWX38_04280	ENOG4105DIW	FeS assembly protein SUFB
BWX38_04295	ENOG4105D56	permease protein
BWX38_04300	ENOG4105EG2	ABC transporter, permease
BWX38_04305	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_04310	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BWX38_04325	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
BWX38_04330	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
BWX38_04345	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
BWX38_04355	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BWX38_04370	ENOG4107RE3	peptidase, S41
BWX38_04380	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
BWX38_04385	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BWX38_04390	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
BWX38_04395	ENOG4105DSF	transport protein
BWX38_04400	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
BWX38_04420	ENOG4105CRK	lysyL-tRNA synthetase
BWX38_04440	ENOG4108YZG	isomerase
BWX38_04455	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
BWX38_04460	ENOG4105MC2	DSBA oxidoreductase
BWX38_04475	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
BWX38_04485	ENOG4105DXB	Major Facilitator superfamily
BWX38_04500	ENOG4108IQE	Amp-dependent synthetase and ligase
BWX38_04515	ENOG4105CQB	FAD linked oxidase domain protein
BWX38_04540	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
BWX38_04555	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
BWX38_04565	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BWX38_04590	ENOG4105C0D	helicase
BWX38_04635	ENOG4108UIN	ybak prolyl-trna synthetase associated region
BWX38_04640	ENOG4105JAB	phenazine biosynthesis protein, phzf family
BWX38_04645	ENOG41089UC	methyltransferase, type 11
BWX38_04660	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BWX38_04665	ENOG4105WH1	Two component transcriptional regulator luxr family
BWX38_04670	ENOG4108XG2	Histidine kinase
BWX38_04680	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BWX38_04705	ENOG4105CJ1	ABC, transporter
BWX38_04725	ENOG4105D63	family UPF0324
BWX38_04730	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BWX38_04735	ENOG4105CUB	amino acid
BWX38_04745	ENOG4105C0B	DNA polymerase III (alpha subunit)
BWX38_04760	ENOG4105DFU	Cell wall formation (By similarity)
BWX38_04780	ENOG41089BK	Glutamine amido-transferase
BWX38_04785	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BWX38_04810	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
BWX38_04815	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
BWX38_04820	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
BWX38_04825	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BWX38_04830	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
BWX38_04835	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
BWX38_04845	ENOG4105CE1	Ferrous iron transport protein b
BWX38_04860	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
BWX38_04900	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
BWX38_04940	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
BWX38_04950	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
BWX38_04965	ENOG4108KGH	TRANSCRIPTIONal
BWX38_04985	ENOG4105EC3	peptidase S51, dipeptidase E
BWX38_04995	ENOG4105D8K	carboxyl transferase
BWX38_05005	ENOG4107WR6	Maf-like protein
BWX38_05015	ENOG4105CEU	Arginine dihydrolase
BWX38_05030	ENOG4105DWF	phosphomethylpyrimidine kinase
BWX38_05040	ENOG4108JIK	carboxylase
BWX38_05060	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
BWX38_05075	ENOG4105C8Y	Acetylornithine aminotransferase
BWX38_05080	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
BWX38_05095	ENOG4107T4V	d-proline reductase
BWX38_05105	ENOG4105CTU	Proline racemase
BWX38_05115	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BWX38_05135	ENOG4105UIB	(ABC) transporter
BWX38_05140	ENOG4108JQ9	ABC transporter
BWX38_05145	ENOG4107TFB	basic membrane
BWX38_05175	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BWX38_05180	ENOG4108EKI	Dehydrogenase
BWX38_05190	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
BWX38_05200	ENOG4105DC1	bifunctional purine biosynthesis protein purh
BWX38_05210	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
BWX38_05215	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BWX38_05245	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BWX38_05270	ENOG4105D01	(LipO)protein
BWX38_05275	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BWX38_05280	ENOG4108UMI	ABC transporter, permease
BWX38_05290	ENOG4105Y3U	Transglycosylase-associated protein
BWX38_05295	ENOG4105WH1	Two component transcriptional regulator luxr family
BWX38_05320	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BWX38_05325	ENOG4105D7W	serine acetyltransferase
BWX38_05330	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
BWX38_05340	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BWX38_05345	ENOG41072RD	Membrane
BWX38_05350	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BWX38_05355	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
BWX38_05375	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
BWX38_05395	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BWX38_05410	ENOG4108097	ATP-binding protein
BWX38_05415	ENOG4105C1J	atp-dependent rna helicase
BWX38_05430	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
BWX38_05435	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BWX38_05440	ENOG4107QVI	Methyltransferase, type 11
BWX38_05445	ENOG4105CS9	pantothenic acid kinase
BWX38_05455	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BWX38_05460	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
BWX38_05465	ENOG4108UJD	30S ribosomal protein S9
BWX38_05470	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BWX38_05490	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
BWX38_05495	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BWX38_05500	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BWX38_05510	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
BWX38_05515	ENOG4108JJB	ABC transporter
BWX38_05525	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
BWX38_05530	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BWX38_05540	ENOG4108MJN	Glycosyl Transferase
BWX38_05545	ENOG4108ZT0	50S ribosomal protein l17
BWX38_05550	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BWX38_05555	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BWX38_05560	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BWX38_05565	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BWX38_05570	ENOG41067V7	50S ribosomal protein L36
BWX38_05575	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
BWX38_05595	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BWX38_05630	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BWX38_05635	ENOG410849U	50S ribosomal protein L30
BWX38_05640	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BWX38_05645	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BWX38_05650	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BWX38_05655	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BWX38_05660	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
BWX38_05665	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BWX38_05670	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BWX38_05675	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BWX38_05680	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BWX38_05685	ENOG4105DRS	transport system, permease
BWX38_05700	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_05710	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BWX38_05715	ENOG41082SA	50s ribosomal protein l29
BWX38_05720	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
BWX38_05725	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BWX38_05730	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
BWX38_05735	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BWX38_05740	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BWX38_05745	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BWX38_05750	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
BWX38_05755	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BWX38_05760	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BWX38_05765	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
BWX38_05770	ENOG4105CX6	glutaminyL-tRNA synthetase
BWX38_05785	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
BWX38_05790	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BWX38_05795	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BWX38_05800	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
BWX38_05805	ENOG4105EE0	oxidoreductase
BWX38_05825	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BWX38_05830	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BWX38_05835	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
BWX38_05845	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BWX38_05850	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BWX38_05855	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
BWX38_05870	ENOG4105XT2	Transcriptional regulator
BWX38_05875	ENOG4107R4N	Cell wall formation (By similarity)
BWX38_05885	ENOG410900P	UPF0336 protein
BWX38_05890	ENOG4105WDJ	50S ribosomal protein L33
BWX38_05930	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BWX38_05935	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BWX38_05940	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BWX38_05945	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
BWX38_05950	ENOG4105DQU	oxidoreductase, subunit beta
BWX38_05955	ENOG4105C9K	Endothelin-converting enzyme 1
BWX38_05965	ENOG41062B0	ABC transporter, permease
BWX38_05970	ENOG4107R9N	ABC transporter
BWX38_05975	ENOG4105C2J	ABC transporter
BWX38_05980	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
BWX38_05990	ENOG4107FQ9	ethanolamine ammonia-lyase
BWX38_05995	ENOG4105CPD	ethanolamine ammonia-lyase
BWX38_06015	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BWX38_06030	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BWX38_06035	ENOG4105DF2	NADH dehydrogenase subunit j
BWX38_06040	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BWX38_06045	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
BWX38_06050	ENOG4108IEH	NADH dehydrogenase subunit g
BWX38_06055	ENOG4107QIZ	NADH dehydrogenase
BWX38_06065	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BWX38_06070	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BWX38_06075	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BWX38_06085	ENOG4105P52	geranylgeranyl reductase
BWX38_06090	ENOG4105E4F	Isochorismate synthase
BWX38_06115	ENOG4105CJ1	ABC, transporter
BWX38_06120	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BWX38_06130	ENOG4105BZ1	(ABC) transporter
BWX38_06150	ENOG4105CMT	Dihydroxyacetone kinase
BWX38_06155	ENOG4108UTZ	Dihydroxyacetone kinase
BWX38_06160	ENOG4105VDH	Dihydroxyacetone kinase
BWX38_06175	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BWX38_06200	ENOG4105DEN	Luciferase family
BWX38_06255	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
BWX38_06270	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
BWX38_06370	ENOG4108IV0	ABC, transporter
BWX38_06375	ENOG4105C0Z	ABC transporter
BWX38_06380	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
BWX38_06385	ENOG4105C32	Amino acid ABC transporter (Permease)
BWX38_06390	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
BWX38_06415	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BWX38_06430	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BWX38_06455	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
BWX38_06470	ENOG4105HDK	L-asparaginase
BWX38_06485	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
BWX38_06490	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
BWX38_06495	ENOG4105C8V	SAICAR synthetase
BWX38_06500	ENOG4105D3R	alkyl hydroperoxide reductase
BWX38_06505	ENOG4108JU3	Alkyl hydroperoxide reductase
BWX38_06515	ENOG4105C83	adenylosuccinate lyase
BWX38_06520	ENOG4105C12	Phosphoribosylglycinamide synthetase
BWX38_06525	ENOG4105VJK	Transcription factor
BWX38_06530	ENOG4105ZGE	Toxic component of a toxin-antitoxin (TA) module. A
BWX38_06535	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BWX38_06550	ENOG4105XTG	Pfam:DUF156
BWX38_06555	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BWX38_06570	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
BWX38_06575	ENOG4105CI3	gtp-binding protein typa
BWX38_06595	ENOG4108SVG	May play a role in the intracellular transport of hydrophobic ligands
BWX38_06600	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
BWX38_06630	ENOG4107NHD	transcriptional regulator
BWX38_06635	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
BWX38_06660	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
BWX38_06665	ENOG4105KDC	50s ribosomal protein l28
BWX38_06670	ENOG41068HZ	50S ribosomal protein L32
BWX38_06680	ENOG4105YK5	50S ribosomal protein L36
BWX38_06685	ENOG4105NRA	50s ribosomal protein l31 type b
BWX38_06690	ENOG4105W0E	50S ribosomal protein L33
BWX38_06700	ENOG4105CKI	cobalamin synthesis protein
BWX38_06710	ENOG4105CC5	ABC transporter
BWX38_06715	ENOG4105DIK	(ABC) transporter
BWX38_06725	ENOG4105DSE	periplasmic solute binding protein
BWX38_06730	ENOG4108MES	Periplasmic binding protein
BWX38_06735	ENOG4105DQ5	transport system permease protein
BWX38_06740	ENOG4108IHU	transport system permease protein
BWX38_06745	ENOG4105E0A	ABC, transporter
BWX38_06765	ENOG4105C01	Dihydroxy-acid dehydratase
BWX38_06770	ENOG4105C7B	Threonine dehydratase
BWX38_06785	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
BWX38_06800	ENOG4105CRE	cytochrome C
BWX38_06810	ENOG4107QIV	Cytochrome c biogenesis protein
BWX38_06815	ENOG4107ZT5	Thiol disulfide interchange protein
BWX38_06820	ENOG4108RH7	phosphoglycerate mutase
BWX38_06825	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BWX38_06830	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
BWX38_06845	ENOG4105II7	pyrroline-5-carboxylate reductase
BWX38_06865	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
BWX38_06875	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BWX38_06880	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BWX38_06895	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
BWX38_06900	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
BWX38_06905	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
BWX38_06915	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
BWX38_06925	ENOG4105D52	delta-aminolevulinic acid dehydratase
BWX38_06930	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
BWX38_06935	ENOG4105CEN	a g-specific adenine glycosylase
BWX38_06945	ENOG4108UCS	ABC, transporter
BWX38_06955	ENOG4105DP9	ABC transporter
BWX38_06965	ENOG4107ZXI	Rhomboid family
BWX38_07025	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BWX38_07040	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BWX38_07060	ENOG4105KRF	dihydroneopterin aldolase
BWX38_07065	ENOG4105EEI	dihydropteroate synthase
BWX38_07070	ENOG4105EUJ	GTP cyclohydrolase i
BWX38_07080	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BWX38_07085	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
BWX38_07095	ENOG4105F0N	pyrophosphate phospho-hydrolase
BWX38_07105	ENOG4105I82	acetyl xylan esterase
BWX38_07110	ENOG4105M4E	phosphohistidine phosphatase, SixA
BWX38_07160	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
BWX38_07170	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BWX38_07175	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BWX38_07205	ENOG4108YYH	Nadph-dependent fmn reductase
BWX38_07250	ENOG4105MA4	psp1 domain protein
BWX38_07260	ENOG4105C6E	dna polymerase iii
BWX38_07265	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BWX38_07275	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BWX38_07285	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BWX38_07290	ENOG4108I5C	dEAD DEAH box helicase
BWX38_07375	ENOG4105P8F	nudix hydrolase
BWX38_07405	ENOG4105BZ4	penicillin-binding protein
BWX38_07435	ENOG4107QK5	Homocysteine s-methyltransferase
BWX38_07440	ENOG410834F	Transcriptional regulator
BWX38_07470	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BWX38_07475	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BWX38_07480	ENOG4105C3U	ABC transporter
BWX38_07485	ENOG4108JQ7	(ABC) transporter
BWX38_07500	ENOG4105D1Q	UPF0246 protein
BWX38_07515	ENOG4108HMQ	sugar kinase
BWX38_07520	ENOG4107Z1W	Fructose transport system kinase
BWX38_07535	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BWX38_07545	ENOG4107QI1	Mate efflux family protein
BWX38_07605	ENOG4105WH1	Two component transcriptional regulator luxr family
BWX38_07630	ENOG4105DQE	DNA ligase
BWX38_07640	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
BWX38_07655	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
BWX38_07670	ENOG4107S2Z	UPF0761 membrane protein
BWX38_07690	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
BWX38_07710	ENOG4105WS7	Cation transport regulator
BWX38_07715	ENOG4107SET	aldo keto reductase
BWX38_07735	ENOG4105DFH	Transport of potassium into the cell (By similarity)
BWX38_07770	ENOG4105CSH	Transporter
BWX38_07775	ENOG4105CWE	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
BWX38_07785	ENOG4105DQR	SNARE associated Golgi
BWX38_07795	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BWX38_07800	ENOG4105BZU	Histidine kinase
BWX38_07805	ENOG4105ETX	regulatoR
BWX38_07810	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BWX38_07820	ENOG4105C4B	ABC transporter, permease
BWX38_07830	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BWX38_07840	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
BWX38_07855	ENOG4105EMU	Dehydrogenase
BWX38_07865	ENOG4105C2X	Arabinose 5-phosphate isomerase
BWX38_07890	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BWX38_07900	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_07905	ENOG4105EF1	ribulokinase
BWX38_07910	ENOG4105DQ4	alcohol dehydrogenase
BWX38_07915	ENOG4105DKT	Transcriptional regulator
BWX38_07920	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BWX38_07925	ENOG4105CPQ	Dehydrogenase
BWX38_07935	ENOG4105C29	acyl-CoA thioesterase
BWX38_07945	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
BWX38_07950	ENOG41090U3	tautomerase
BWX38_07980	ENOG4108UMN	azlc family
BWX38_08000	ENOG4105D7A	ATP-binding protein
BWX38_08015	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
BWX38_08020	ENOG4108IJ8	ABC transporter
BWX38_08030	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
BWX38_08040	ENOG4107S1E	Beta-lactamase
BWX38_08080	ENOG4108Z6B	deaminase
BWX38_08090	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BWX38_08115	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
BWX38_08120	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BWX38_08125	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BWX38_08150	ENOG4108KGH	TRANSCRIPTIONal
BWX38_08155	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_08160	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BWX38_08190	ENOG4105CDH	Citrulline--aspartate ligase
BWX38_08210	ENOG4108K4B	hydrolase
BWX38_08230	ENOG4105EG2	ABC transporter, permease
BWX38_08250	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BWX38_08270	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
BWX38_08280	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
BWX38_08290	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
BWX38_08295	ENOG4105CPP	Dehydrogenase, E1 component
BWX38_08305	ENOG4107VFM	Dehydrogenase
BWX38_08350	ENOG4105CSH	Transporter
BWX38_08355	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BWX38_08360	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BWX38_08365	ENOG4105ENR	peptidase, M24
BWX38_08375	ENOG4108JPW	Aminotransferase
BWX38_08415	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
BWX38_08420	ENOG4105C5I	Dehydrogenase
BWX38_08490	ENOG4106H3A	restriction
BWX38_08520	ENOG4105GR3	Histidine kinase
BWX38_08535	ENOG4108HKT	sucrose-6-phosphate hydrolase
BWX38_08540	ENOG4105DKT	Transcriptional regulator
BWX38_08545	ENOG4105CMG	Carbohydrate kinase
BWX38_08550	ENOG4105CMG	Carbohydrate kinase
BWX38_08560	ENOG4107W7X	Aldolase
BWX38_08565	ENOG4105CV8	reductase
BWX38_08570	ENOG41061GT	Aldolase
BWX38_08575	ENOG4105CPQ	Dehydrogenase
BWX38_08585	ENOG4105CSH	Transporter
BWX38_08605	ENOG4105DSQ	Nitric oxide reductase
BWX38_08640	ENOG4107QWR	cellulase (EC 3.2.1.4)
BWX38_08650	ENOG4105CG3	alpha amylase, catalytic region
BWX38_08680	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
BWX38_08685	ENOG4105CG3	alpha amylase, catalytic region
BWX38_08695	ENOG4105BZ7	extracellular solute-binding protein family 1
BWX38_08700	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
BWX38_08705	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
BWX38_08710	ENOG4105KT7	mgtC SapB transporter
BWX38_08725	ENOG4105EBR	Carboxylesterase
BWX38_08740	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
BWX38_08745	ENOG4105DRS	transport system, permease
BWX38_08750	ENOG4105CG3	alpha amylase, catalytic region
BWX38_08765	ENOG4105BZ1	(ABC) transporter
BWX38_08770	ENOG4105BZ1	(ABC) transporter
BWX38_08785	ENOG4105CIF	Ornithine Cyclodeaminase
BWX38_08805	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
BWX38_08820	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_08835	ENOG41062D9	Histidine kinase
BWX38_08845	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
BWX38_08855	ENOG4105PGM	cation diffusion facilitator family transporter
BWX38_08870	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
BWX38_08885	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
BWX38_08900	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
BWX38_08905	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
BWX38_08915	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
BWX38_08920	ENOG4105DBE	peroxidase
BWX38_08940	ENOG4108IQE	Amp-dependent synthetase and ligase
BWX38_08955	ENOG4108IXY	short-chain dehydrogenase reductase
BWX38_09000	ENOG4105CQB	FAD linked oxidase domain protein
BWX38_09010	ENOG4105WH1	Two component transcriptional regulator luxr family
BWX38_09015	ENOG4108U8T	Mannosyltransferase
BWX38_09020	ENOG4105CJ1	ABC, transporter
BWX38_09045	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BWX38_09055	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
BWX38_09060	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
BWX38_09065	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
BWX38_09070	ENOG4105C5I	Dehydrogenase
BWX38_09075	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
BWX38_09085	ENOG4105C85	amino acid
BWX38_09155	ENOG4107QI1	Mate efflux family protein
BWX38_09170	ENOG4108TFM	Kinase, PfkB family
BWX38_09180	ENOG4108Z66	YbaK ebsC protein
BWX38_09190	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BWX38_09200	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_09215	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
BWX38_09220	ENOG4105KVH	Transcriptional regulator
BWX38_09235	ENOG4108HKT	sucrose-6-phosphate hydrolase
BWX38_09240	ENOG4105D7K	pfkb domain protein
BWX38_09245	ENOG410839S	Toxic component of a toxin-antitoxin (TA) module (By similarity)
BWX38_09265	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
BWX38_09275	ENOG4105IDI	abc transporter atp-binding protein
BWX38_09280	ENOG4108QVN	serine threonine protein kinase
BWX38_09290	ENOG4105CTQ	phosphohexokinase
BWX38_09295	ENOG4105DCF	alanine dehydrogenase
BWX38_09300	ENOG4105E5G	Alpha beta hydrolase fold
BWX38_09345	ENOG4105K6T	rare lipoprotein A
BWX38_09355	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
BWX38_09370	ENOG4105E2D	ec 3.2.1.52
BWX38_09395	ENOG4105CMQ	Chloride channel
BWX38_09405	ENOG4105CAG	UPF0210 protein
BWX38_09420	ENOG4105C9Q	fumarate hydratase class II
BWX38_09425	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
BWX38_09430	ENOG41064HX	Suppressor of fused protein (SUFU)
BWX38_09440	ENOG4105CTZ	aminopeptidase c
BWX38_09445	ENOG4105CJ1	ABC, transporter
BWX38_09460	ENOG4105F27	Major Facilitator
BWX38_09470	ENOG4105E98	transcriptional regulator DeoR family
BWX38_09475	ENOG4105CXT	aspartate transcarbamylase
BWX38_09490	ENOG4105D8X	mechanosensitive ion channel
BWX38_09500	ENOG4105BZW	Glycerate kinase
BWX38_09510	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BWX38_09515	ENOG4105C26	Dehydrogenase
BWX38_09520	ENOG4105C09	Bile acid
BWX38_09525	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
BWX38_09555	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BWX38_09560	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
BWX38_09565	ENOG4107RHR	regulatoR
BWX38_09575	ENOG4105C0H	protease
BWX38_09590	ENOG4105DRS	transport system, permease
BWX38_09600	ENOG4108JE9	extracellular solute-binding protein family 1
BWX38_09610	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_09615	ENOG4105C3M	thioredoxin reductase
BWX38_09620	ENOG4105KVH	Transcriptional regulator
BWX38_09635	ENOG4105K63	Thioredoxin
BWX38_09665	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BWX38_09675	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
BWX38_09685	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_09695	ENOG4107ZR7	Membrane
BWX38_09705	ENOG4105D9R	oxidoreductase
BWX38_09720	ENOG4107QNK	)-transporter
BWX38_09725	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_09730	ENOG4107QNK	)-transporter
BWX38_09735	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_09740	ENOG4105F0H	myo-inositol catabolism protein
BWX38_09745	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
BWX38_09750	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
BWX38_09755	ENOG4105C26	Dehydrogenase
BWX38_09770	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BWX38_09775	ENOG4105CPF	Cell wall formation (By similarity)
BWX38_09790	ENOG4105DQE	DNA ligase
BWX38_09800	ENOG4107QJE	Chromosome Partitioning Protein
BWX38_09815	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
BWX38_09825	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
BWX38_09835	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
BWX38_09845	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BWX38_09855	ENOG4105KPY	Small multidrug resistance protein
BWX38_09865	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BWX38_09870	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BWX38_09875	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
BWX38_09885	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BWX38_09890	ENOG4105K7N	UPF0232 protein
BWX38_09900	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BWX38_09905	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
BWX38_09910	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
BWX38_09920	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_09925	ENOG4105C2J	ABC transporter
BWX38_09930	ENOG4105CNN	ABC, transporter
BWX38_09935	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
BWX38_09940	ENOG4108RVA	ribokinase
BWX38_09945	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
BWX38_09970	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
BWX38_09985	ENOG4106F59	XRE family Transcriptional regulator
BWX38_09990	ENOG4105YXB	Toxic component of a toxin-antitoxin (TA) module. A
BWX38_10040	ENOG4105CIG	ABC transporter
BWX38_10045	ENOG4105FDK	ABC transporter
BWX38_10055	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BWX38_10070	ENOG4105C6K	Malic enzyme
BWX38_10075	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
BWX38_10080	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
BWX38_10100	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
BWX38_10105	ENOG4105F1A	Pyruvate formate-lyase
BWX38_10165	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
BWX38_10175	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BWX38_10235	ENOG4105D5G	Transposase
BWX38_10255	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
BWX38_10270	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
BWX38_10275	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
BWX38_10295	ENOG4107VMI	polysaccharide deacetylase
BWX38_10305	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
BWX38_10315	ENOG4105CPQ	Dehydrogenase
BWX38_10320	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
BWX38_10325	ENOG4105DT3	PTS system, galactitol-specific IIc component
BWX38_10335	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BWX38_10340	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BWX38_10360	ENOG4105DVE	abc transporter atp-binding protein
BWX38_10370	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
BWX38_10380	ENOG4105E5Q	amino acid AbC transporter
BWX38_10385	ENOG4105CDA	abc transporter atp-binding protein
BWX38_10390	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BWX38_10405	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BWX38_10410	ENOG4105I1K	ABC transporter
BWX38_10415	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
BWX38_10435	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BWX38_10500	ENOG4105C26	Dehydrogenase
BWX38_10510	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
BWX38_10540	ENOG4105CKU	formyltetrahydrofolate synthetase
BWX38_10565	ENOG4105C19	ABC transporter
BWX38_10570	ENOG4105WH1	Two component transcriptional regulator luxr family
BWX38_10585	ENOG4105YES	addiction module antidote protein
BWX38_10590	ENOG4105VUH	addiction module killer protein
BWX38_10595	ENOG4105E0Y	RtcB Protein
BWX38_10605	ENOG4105BZ1	(ABC) transporter
BWX38_10630	ENOG4105EDW	glycosyl transferase, family 39
BWX38_10640	ENOG4105BZU	Histidine kinase
BWX38_10645	ENOG4105EDW	glycosyl transferase, family 39
BWX38_10650	ENOG4105BZU	Histidine kinase
BWX38_10660	ENOG4105GR3	Histidine kinase
BWX38_10665	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BWX38_10675	ENOG4107R16	Multicopper oxidase
BWX38_10710	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
BWX38_10725	ENOG410635A	Membrane
BWX38_10750	ENOG4105CV8	reductase
BWX38_10785	ENOG4105K6T	rare lipoprotein A
BWX38_10790	ENOG4107TTQ	Alpha beta hydrolase fold
BWX38_10800	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
BWX38_10820	ENOG41067SE	Tetr family transcriptional regulator
BWX38_10825	ENOG4105EYF	MMPL domain protein
BWX38_10855	ENOG4108JQ1	Dehydrogenase
BWX38_10860	ENOG4105BZ4	penicillin-binding protein
BWX38_10870	ENOG4105C2C	drug resistance transporter, Bcr CflA
BWX38_10880	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BWX38_10885	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BWX38_10890	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
BWX38_10895	ENOG4107RPQ	ABC transporter
BWX38_10910	ENOG4105C6K	Malic enzyme
BWX38_10930	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
BWX38_10935	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
BWX38_10940	ENOG4105D8K	carboxyl transferase
BWX38_10950	ENOG4107QSA	Oxaloacetate decarboxylase
BWX38_10955	ENOG4105D9Q	decarboxylase (Beta subunit)
BWX38_10970	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BWX38_10995	ENOG4105CTQ	phosphohexokinase
BWX38_11035	ENOG4105K78	MarR family Transcriptional regulator
BWX38_11045	ENOG4105C59	p-type ATPase
BWX38_11055	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
BWX38_11060	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
BWX38_11095	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
BWX38_11110	ENOG4105CHF	Glutathione S-transferase
BWX38_11115	ENOG4108J59	Extracellular solute-binding protein, family 5
BWX38_11120	ENOG4108JQ6	ABC transporter
BWX38_11125	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BWX38_11130	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BWX38_11145	ENOG4105F4R	Transcriptional regulator mode
BWX38_11170	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
BWX38_11175	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
BWX38_11180	ENOG4108SQ9	flavin reductase domain protein, FMN-binding
BWX38_11200	ENOG4108IUE	nitrate reductase beta subunit
BWX38_11220	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BWX38_11230	ENOG4108ZAF	Molybdopterin
BWX38_11240	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BWX38_11245	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BWX38_11255	ENOG4105DWF	phosphomethylpyrimidine kinase
BWX38_11260	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BWX38_11265	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
BWX38_11280	ENOG41062B0	ABC transporter, permease
BWX38_11285	ENOG4107R9N	ABC transporter
BWX38_11290	ENOG4105C2J	ABC transporter
BWX38_11300	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_11305	ENOG41068JE	domain protein
BWX38_11320	ENOG4105DZW	Dipeptidase
BWX38_11330	ENOG4105C26	Dehydrogenase
BWX38_11340	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_11345	ENOG4105D2H	Uronic isomerase
BWX38_11350	ENOG4105DEI	Mannitol dehydrogenase
BWX38_11355	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
BWX38_11375	ENOG4105DTQ	mandelate racemase muconate lactonizing
BWX38_11395	ENOG4105KT7	mgtC SapB transporter
BWX38_11405	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_11410	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
BWX38_11415	ENOG4105BZ7	extracellular solute-binding protein family 1
BWX38_11420	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
BWX38_11480	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
BWX38_11535	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
BWX38_11540	ENOG4105C4R	Atp-dependent dna helicase
BWX38_11575	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BWX38_11650	ENOG4105C4X	radical SAM domain protein
BWX38_11660	ENOG4105VG5	Membrane
BWX38_11665	ENOG4105CBG	Sulfatase
BWX38_11675	ENOG4105E2R	ROK family
BWX38_11680	ENOG4105CBG	Sulfatase
BWX38_11700	ENOG4105C8Y	Acetylornithine aminotransferase
BWX38_11710	ENOG4105EIP	mannose-6-phosphate isomerase
BWX38_11720	ENOG4108UHU	Aldolase
BWX38_11725	ENOG4108FUF	Transcriptional regulator, IclR family
BWX38_11730	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_11735	ENOG4107QZW	Altronate oxidoreductase
BWX38_11740	ENOG4105CTX	dehydratase
BWX38_11745	ENOG4105D2H	Uronic isomerase
BWX38_11790	ENOG4107QN2	dihydrolipoyl dehydrogenase
BWX38_11795	ENOG4105F9F	transposase
BWX38_11815	ENOG4105CNT	hydrolase family 2
BWX38_11885	ENOG4105CT4	transporter
BWX38_11920	ENOG4105EQN	UPF0261 protein
BWX38_11925	ENOG41073TP	transcriptional regulator
BWX38_11940	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_11945	ENOG4105D1H	recombination factor protein RarA
BWX38_11960	ENOG4105C84	Histidine ammonia-lyase
BWX38_11965	ENOG4105CI2	imidazolone-5-propionate hydrolase
BWX38_11970	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BWX38_11975	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
BWX38_11980	ENOG4105CGP	Urocanate hydratase
BWX38_11985	ENOG4108K8U	Glycerol operon regulatory protein
BWX38_11990	ENOG4105D1H	recombination factor protein RarA
BWX38_12005	ENOG4105DKW	ABC transporter
BWX38_12015	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BWX38_12025	ENOG4107T5V	SNARE associated Golgi
BWX38_12030	ENOG4105CPQ	Dehydrogenase
BWX38_12045	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
BWX38_12080	ENOG4105C37	(CBS) domain
BWX38_12090	ENOG4108Z7F	N-acetyltransferase
BWX38_12110	ENOG4105F95	Monooxygenase
BWX38_12205	ENOG4105KDP	XRE family
BWX38_12225	ENOG4108C33	Resolvase
BWX38_12405	ENOG4105BZ4	penicillin-binding protein
BWX38_12425	ENOG4107T8Q	Glycosyl transferase (Group 1
BWX38_12465	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BWX38_12495	ENOG4105DM4	PTS System
BWX38_12500	ENOG4105DE4	1-phosphofructokinase
BWX38_12505	ENOG4105E98	transcriptional regulator DeoR family
BWX38_12510	ENOG4105DRP	amino acid AbC transporter
BWX38_12515	ENOG4108Q1T	ABC transporter
BWX38_12520	ENOG4107UBR	Extracellular solute-binding protein family 3
BWX38_12525	ENOG4105CDA	abc transporter atp-binding protein
BWX38_12530	ENOG4108IJ1	Dehydrogenase
BWX38_12545	ENOG4108MJN	Glycosyl Transferase
BWX38_12550	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BWX38_12560	ENOG4105CKK	Glycosyl transferase, family 2
BWX38_12605	ENOG4105KHC	sulfurtransferase
BWX38_12620	ENOG4105CQ7	ATP-dependent helicase
BWX38_12635	ENOG4108VX5	3-methyladenine DNA glycosylase
BWX38_12655	ENOG4108V8F	Transcriptional regulator, MarR family
BWX38_12660	ENOG4108V06	Glutathione peroxidase
BWX38_12665	ENOG4105C3M	thioredoxin reductase
BWX38_12670	ENOG4105K63	Thioredoxin
BWX38_12675	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
BWX38_12680	ENOG4105CDU	Replicative dna helicase
BWX38_12685	ENOG4105VPX	protein, conserved in bacteria
BWX38_12700	ENOG4105K6T	rare lipoprotein A
BWX38_12710	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
BWX38_12715	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
BWX38_12730	ENOG41073TP	transcriptional regulator
BWX38_12735	ENOG4105DAA	L-lactate
BWX38_12740	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
BWX38_12745	ENOG4107QR9	Iron-sulfur cluster binding protein
BWX38_12750	ENOG41080R8	Conserved Protein
BWX38_12755	ENOG4105BZ1	(ABC) transporter
BWX38_12760	ENOG4108JJ9	ABC, transporter
BWX38_12765	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
BWX38_12770	ENOG4105C4M	(Ubiquinol oxidase) subunit I
BWX38_12780	ENOG4105WH1	Two component transcriptional regulator luxr family
BWX38_12810	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BWX38_12815	ENOG4108JB8	alcohol dehydrogenase
BWX38_12830	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
BWX38_12840	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_12855	ENOG4105KBX	Transcriptional regulator, TetR family
BWX38_12860	ENOG4107VXZ	Hydrolase
BWX38_12875	ENOG4105C5B	carbamate kinase
BWX38_12885	ENOG4107REC	cytoplasmic protein
BWX38_12890	ENOG4107R1Q	Membrane protein FdrA
BWX38_12895	ENOG4107YCY	Transcriptional regulator
BWX38_12915	ENOG4105C5R	Aminotransferase
BWX38_12925	ENOG4105CK2	sodium dicarboxylate symporter
BWX38_12930	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
BWX38_12940	ENOG4105K8R	UPF0145 protein
BWX38_12945	ENOG4105CRK	lysyL-tRNA synthetase
BWX38_12950	ENOG4105ZJT	Cell division protein CrgA
BWX38_12970	ENOG4105CJN	penicillin-binding protein
BWX38_12985	ENOG4105HZM	Fha domain containing protein
BWX38_12990	ENOG4105TV9	FHA Domain-Containing protein
BWX38_13000	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
BWX38_13005	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
BWX38_13025	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
BWX38_13030	ENOG4105D3Q	Sugar transferase
BWX38_13045	ENOG4108KGH	TRANSCRIPTIONal
BWX38_13050	ENOG4105D3Q	Sugar transferase
BWX38_13055	ENOG4107YJ4	chain length determinant protein
BWX38_13070	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
BWX38_13140	ENOG4105CSH	Transporter
BWX38_13165	ENOG4105C85	amino acid
BWX38_13170	ENOG4108X07	Tetr family transcriptional regulator
BWX38_13175	ENOG4105CIG	ABC transporter
BWX38_13220	ENOG41087ID	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
BWX38_13225	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
BWX38_13250	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BWX38_13265	ENOG410667J	hydrolase
BWX38_13270	ENOG4108HCJ	Hydrolase
BWX38_13275	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BWX38_13295	ENOG4105CFH	Aspartokinase
BWX38_13320	ENOG4105D94	Major Facilitator Superfamily
BWX38_13325	ENOG4107RSM	transcriptional regulator
BWX38_13345	ENOG41085J0	Protein CrcB homolog
BWX38_13350	ENOG41083TI	Protein CrcB homolog
BWX38_13360	ENOG4108FN7	Aldo keto reductase
BWX38_13380	ENOG4108V1U	phospholipid-binding protein
BWX38_13390	ENOG4105CQR	helicase
BWX38_13400	ENOG4107QP8	phosphohexose isomerase
BWX38_13415	ENOG4105IE8	Alpha-ketoglutarate permease
BWX38_13420	ENOG4105CV8	reductase
BWX38_13425	ENOG4105C75	arginyL-tRNA synthetase
BWX38_13445	ENOG4105C54	Major Facilitator superfamily
BWX38_13460	ENOG4105C26	Dehydrogenase
BWX38_13465	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
BWX38_13470	ENOG4105DET	Rhamnulokinase
BWX38_13475	ENOG4105C9F	isomerase
BWX38_13485	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
BWX38_13490	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_13530	ENOG4105ETE	Transcriptional regulator (LacI family
BWX38_13540	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BWX38_13545	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BWX38_13555	ENOG4108IJ0	Aspartate ammonia-lyase
BWX38_13595	ENOG4105C57	major facilitator superfamily
BWX38_13600	ENOG4108IG5	Transcriptional regulator
BWX38_13615	ENOG4108JQ7	(ABC) transporter
BWX38_13620	ENOG4107QNK	)-transporter
BWX38_13635	ENOG4105CJ1	ABC, transporter
BWX38_13640	ENOG4105EJ2	Transcriptional regulator
BWX38_13655	ENOG4105DSB	aldose 1-epimerase
BWX38_13660	ENOG4105EAC	phosphoserine phosphatase
BWX38_13665	ENOG4107RNR	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA (By similarity)
BWX38_13670	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
BWX38_13675	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
BWX38_13690	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BWX38_13695	ENOG4105BZU	Histidine kinase
BWX38_13700	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
BWX38_13715	ENOG4105CFG	Acts as a chaperone (By similarity)
BWX38_13720	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BWX38_13725	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
BWX38_13730	ENOG4105KNI	merR family transcriptional Regulator
BWX38_13735	ENOG4105CPQ	Dehydrogenase
BWX38_13740	ENOG4107FQX	Alpha-acetolactate decarboxylase
BWX38_13745	ENOG4107WGA	YidE YbjL
BWX38_13750	ENOG4105C85	amino acid
BWX38_13760	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BWX38_13765	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
BWX38_13775	ENOG4105WH1	Two component transcriptional regulator luxr family
BWX38_13780	ENOG4105BZU	Histidine kinase
BWX38_13790	ENOG4107SCA	Formamidase (EC 3.5.1.49)
BWX38_13805	ENOG4105WYW	fructose-bisphosphate aldolase
BWX38_13820	ENOG4105DRS	transport system, permease
BWX38_13830	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
BWX38_13835	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
BWX38_13840	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
BWX38_13850	ENOG4105EDK	PfkB domain protein
BWX38_13855	ENOG4105E98	transcriptional regulator DeoR family
BWX38_13860	ENOG4105F8D	glycoside hydrolase family 4
BWX38_13875	ENOG4105ECB	domain protein
BWX38_13890	ENOG4105ECR	NmrA family
BWX38_13910	ENOG4105DZR	Type I site-specific deoxyribonuclease
BWX38_13920	ENOG4105CVR	type I restriction-modification system
BWX38_13960	ENOG4105K5B	UPF0225 protein
BWX38_13965	ENOG4108IJ7	Glycine betaine
BWX38_13970	ENOG4107SQ8	Glycine betaine
BWX38_13985	ENOG4107U9B	transcriptional regulator
BWX38_13990	ENOG4105CJ1	ABC, transporter
BWX38_14005	ENOG4105E90	ABC transporter
BWX38_14010	ENOG4108IJ8	ABC transporter
BWX38_14015	ENOG4105E90	ABC transporter
BWX38_14025	ENOG4105C26	Dehydrogenase
BWX38_14030	ENOG4105CHM	Aminotransferase
BWX38_14050	ENOG4108V0P	LemA family
BWX38_14055	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
BWX38_14075	ENOG4107SBE	Glycosyl transferase (Group 1
BWX38_14085	ENOG4107Y2G	Glycosyl transferase (Group 1
BWX38_14095	ENOG4105PSV	Polysaccharide Biosynthesis Protein
BWX38_14100	ENOG4107YJ4	chain length determinant protein
BWX38_14120	ENOG4105DQR	SNARE associated Golgi
BWX38_14135	ENOG4107RCW	fructose-bisphosphate aldolase
BWX38_14140	ENOG4107QSA	Oxaloacetate decarboxylase
BWX38_14145	ENOG4107QX3	carboxylase
BWX38_14150	ENOG4107QX3	carboxylase
BWX38_14155	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
BWX38_14165	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
BWX38_14170	ENOG410849S	phosphocarrier protein (HPr)
BWX38_14175	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BWX38_14180	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
BWX38_14185	ENOG4105BZU	Histidine kinase
BWX38_14200	ENOG4108VJ1	Transcriptional regulator (CarD family
BWX38_14205	ENOG41082GB	PTS system galactitol-specific transporter subunit IIA
BWX38_14215	ENOG4105DT3	PTS system, galactitol-specific IIc component
BWX38_14225	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
BWX38_14240	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
BWX38_14245	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
BWX38_14265	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
BWX38_14270	ENOG4105EQ0	Major Facilitator superfamily
BWX38_14285	ENOG4105C8N	cysteinyl-tRNA synthetase
BWX38_14300	ENOG4105C28	cystathionine
BWX38_14375	ENOG4107URF	beta-phospho-glucomutase
BWX38_14385	ENOG4105EJQ	L-serine dehydratase
BWX38_14390	ENOG4105DKQ	ROK family
BWX38_14400	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
BWX38_14405	ENOG4105DRS	transport system, permease
BWX38_14410	ENOG4105CPQ	Dehydrogenase
BWX38_14415	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BWX38_14425	ENOG4108UVJ	appr-1-p processing domain protein
BWX38_14430	ENOG4108M15	ABC transporter
BWX38_14440	ENOG4108ZGX	Histidine kinase
BWX38_14445	ENOG4108S01	response regulator
BWX38_14455	ENOG4105CVJ	phosphoglycerate mutase
BWX38_14475	ENOG4105BZU	Histidine kinase
BWX38_14480	ENOG4105WH1	Two component transcriptional regulator luxr family
BWX38_14485	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BWX38_14490	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BWX38_14500	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
BWX38_14505	ENOG4105E4R	Precorrin-3B C17-methyltransferase
BWX38_14510	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BWX38_14525	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
BWX38_14535	ENOG4108V4M	Cobalt abc transporter
BWX38_14540	ENOG4108JJB	ABC transporter
BWX38_14545	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
BWX38_14550	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BWX38_14555	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BWX38_14560	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
BWX38_14570	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
BWX38_14575	ENOG4108YZT	Adenosylcobinamide kinase
BWX38_14600	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
BWX38_14605	ENOG4105EIP	mannose-6-phosphate isomerase
BWX38_14615	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BWX38_14640	ENOG4106N3A	copper homeostasis protein cutc
BWX38_14660	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
BWX38_14665	ENOG4105VEQ	Cold shock protein
BWX38_14680	ENOG4105C7N	Xanthine uracil vitamin C permease
BWX38_14700	ENOG4105CE4	GlcNAc 6-P deacetylase
BWX38_14705	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
BWX38_14710	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BWX38_14720	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
BWX38_14725	ENOG4105D7K	pfkb domain protein
BWX38_14735	ENOG4105DH8	myo-inositol catabolism
BWX38_14740	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
BWX38_14750	ENOG41060NJ	transcriptional regulator
BWX38_14755	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
BWX38_14760	ENOG4105C54	Major Facilitator superfamily
BWX38_14785	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
BWX38_14800	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
BWX38_14910	ENOG4105E4C	Lytic transglycosylase catalytic
BWX38_14960	ENOG4105IIP	Membrane
BWX38_14980	ENOG4108594	Permease of the drug metabolite transporter
BWX38_14990	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
BWX38_15070	ENOG4105C0D	helicase
BWX38_15095	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
BWX38_15135	ENOG4108Z0Z	intracellular protease Pfpi family
BWX38_15150	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
BWX38_15195	ENOG4105P4J	Allophanate hydrolase, subunit 1
BWX38_15205	ENOG4105C2W	permease
BWX38_15220	ENOG4105F8V	Hydrolase, tatD family
BWX38_15225	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BWX38_15230	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
BWX38_15235	ENOG41082F9	transcriptional regulator
BWX38_15240	ENOG4105U5Y	Transcriptional regulator
BWX38_15250	ENOG4107U1N	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BWX38_15255	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BWX38_15260	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
BWX38_15265	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
BWX38_15285	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BWX38_15315	ENOG4105EZR	dyp-type peroxidase family protein
BWX38_15335	ENOG4106V2I	dimethylaminohydrolase
BWX38_15375	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
BWX38_15380	ENOG41084BS	50S ribosomal protein L35
BWX38_15385	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
BWX38_15390	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
BWX38_15405	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BWX38_15410	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
BWX38_15415	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BWX38_15430	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
BWX38_15465	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
BWX38_15470	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
BWX38_15485	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
BWX38_15500	ENOG4105C7Z	Conserved Protein
BWX38_15505	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BWX38_15515	ENOG4108IAB	Phoh family
BWX38_15525	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BWX38_15530	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
BWX38_15535	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
BWX38_15545	ENOG4105DFM	M18 family aminopeptidase
BWX38_15565	ENOG4105C3G	gtp-binding protein
BWX38_15570	ENOG4105CVR	type I restriction-modification system
BWX38_15575	ENOG4107XZC	Restriction modification system DNA (Specificity
BWX38_15580	ENOG4105DZR	Type I site-specific deoxyribonuclease
BWX38_15655	ENOG41080ET	plasmid maintenance system killer protein
BWX38_15660	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
BWX38_15675	ENOG4105DIM	ABC transporter
BWX38_15680	ENOG4105CIG	ABC transporter
BWX38_15690	ENOG41080ET	plasmid maintenance system killer protein
BWX38_15695	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
BWX38_15770	ENOG41065RQ	ADP-ribosylation crystallin J1
BWX38_15785	ENOG4105BZ1	(ABC) transporter
BWX38_15790	ENOG4108ZM9	phosphoglycerate mutase
BWX38_15810	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
BWX38_15815	ENOG4108RWI	nicotinamidase
BWX38_15845	ENOG4105CSH	Transporter
BWX38_15850	ENOG4105CSH	Transporter
BWX38_15875	ENOG4105RH4	Glycine cleavage system transcriptional repressor
BWX38_15895	ENOG4108IQI	permease
BWX38_15915	ENOG4105CMN	Methylmalonyl-coA mutase
BWX38_15920	ENOG4105D5P	Methylmalonyl-coA mutase
BWX38_15930	ENOG410848D	S4 domain protein YaaA
BWX38_15950	ENOG4105E5Q	amino acid AbC transporter
BWX38_15960	ENOG4106PMH	Extracellular solute-binding protein family 3
BWX38_15980	ENOG4105CC5	ABC transporter
BWX38_15985	ENOG4105DIK	(ABC) transporter
BWX38_16005	ENOG4105C26	Dehydrogenase
BWX38_16010	ENOG4105CPQ	Dehydrogenase
BWX38_16015	ENOG4105CMT	Dihydroxyacetone kinase
BWX38_16020	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
BWX38_16025	ENOG4105E98	transcriptional regulator DeoR family
BWX38_16030	ENOG4107YVI	ribose 5-phosphate isomerase
BWX38_16040	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
BWX38_16055	ENOG4105EF1	ribulokinase
BWX38_16090	ENOG4107Y80	Major Facilitator superfamily
BWX38_16095	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BWX38_16100	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
BWX38_16105	ENOG4107S1E	Beta-lactamase
BWX38_16110	ENOG4107RBI	VanW family
BWX38_16115	ENOG4108Z4U	Ferredoxin
BWX38_16135	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
BWX38_16145	ENOG4108URH	decarboxylase
BWX38_16160	ENOG4107QPH	glycogen) synthase
BWX38_16165	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
BWX38_16195	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
BWX38_16200	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
BWX38_16235	ENOG4107T6F	Xaa-Pro aminopeptidase
BWX38_16250	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
BWX38_16255	ENOG4105CUB	amino acid
BWX38_16275	ENOG4105D7N	magnesium and cobalt transport protein CorA
BWX38_16300	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
BWX38_16310	ENOG4105EGD	dinuclear metal center protein, YbgI family
BWX38_16325	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
BWX38_16335	ENOG4105C5F	glutamine synthetase
BWX38_16355	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
BWX38_16360	ENOG4105CJW	magnesium transporter
BWX38_16365	ENOG4105C5H	ABC transporter
BWX38_16375	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BWX38_16390	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
BWX38_16435	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
BWX38_16440	ENOG4105BZ9	Cytochrome C oxidase, subunit I
BWX38_16445	ENOG4105MCD	Part of cytochrome c oxidase, its function is
BWX38_16460	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
BWX38_16465	ENOG4107EUI	c reductase, iron-sulfur
BWX38_16470	ENOG4107UDY	cytochrome C
BWX38_16475	ENOG4105CCU	oxidase (Subunit III)
BWX38_16485	ENOG4107S1N	anthranilate phosphoribosyltransferase
BWX38_16530	ENOG4105DKQ	ROK family
BWX38_16550	ENOG4105WH1	Two component transcriptional regulator luxr family
BWX38_16555	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
BWX38_16580	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
BWX38_16590	ENOG4105SYT	Methylenetetrahydrofolate reductase
BWX38_16595	ENOG4105C4R	Atp-dependent dna helicase
BWX38_16615	ENOG4105D7T	ABC transporter
BWX38_16620	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
BWX38_16630	ENOG4108J5G	6-phosphogluconate dehydrogenase
BWX38_16635	ENOG4105C6Z	Gluconate
BWX38_16640	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
BWX38_16660	ENOG4105CJ1	ABC, transporter
BWX38_16665	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWX38_16670	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)