locus-tag	class	description
FEZ32_00020	ENOG410829K	Lysine exporter protein (Lyse ygga)
FEZ32_00035	ENOG4105KA0	thioesterase Superfamily protein
FEZ32_00050	ENOG4105CA9	Pyruvate kinase
FEZ32_00065	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FEZ32_00080	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
FEZ32_00085	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FEZ32_00090	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FEZ32_00100	ENOG4105DFU	Cell wall formation (By similarity)
FEZ32_00105	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FEZ32_00115	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FEZ32_00120	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FEZ32_00135	ENOG4105CJN	penicillin-binding protein
FEZ32_00145	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FEZ32_00150	ENOG4108V6E	Cell division protein mraZ
FEZ32_00155	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FEZ32_00165	ENOG4105F8C	transglutaminase domain-containing protein
FEZ32_00180	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FEZ32_00185	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FEZ32_00190	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FEZ32_00200	ENOG4105CJ1	ABC, transporter
FEZ32_00215	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
FEZ32_00230	ENOG4105E2Y	ABC, transporter
FEZ32_00250	ENOG4105C4R	Atp-dependent dna helicase
FEZ32_00265	ENOG4105EAH	synthase
FEZ32_00290	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
FEZ32_00295	ENOG4105WH1	Two component transcriptional regulator luxr family
FEZ32_00320	ENOG4105DKQ	ROK family
FEZ32_00325	ENOG4105ZXU	NLP P60 protein
FEZ32_00365	ENOG4107S1N	anthranilate phosphoribosyltransferase
FEZ32_00375	ENOG4105CCU	oxidase (Subunit III)
FEZ32_00380	ENOG4107UDY	cytochrome C
FEZ32_00385	ENOG4107EUI	c reductase, iron-sulfur
FEZ32_00390	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FEZ32_00410	ENOG4105MCD	Part of cytochrome c oxidase, its function is
FEZ32_00415	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FEZ32_00420	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
FEZ32_00465	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FEZ32_00480	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FEZ32_00490	ENOG4105C5H	ABC transporter
FEZ32_00500	ENOG4105E2K	Glycosyl transferase (Group 1
FEZ32_00515	ENOG4105C5F	glutamine synthetase
FEZ32_00575	ENOG4105EGD	dinuclear metal center protein, YbgI family
FEZ32_00580	ENOG4105DWK	Membrane
FEZ32_00585	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
FEZ32_00595	ENOG4105C5F	glutamine synthetase
FEZ32_00605	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FEZ32_00610	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FEZ32_00695	ENOG4105D7N	magnesium and cobalt transport protein CorA
FEZ32_00715	ENOG4105CUB	amino acid
FEZ32_00720	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FEZ32_00730	ENOG4107T6F	Xaa-Pro aminopeptidase
FEZ32_00760	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
FEZ32_00765	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FEZ32_00780	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FEZ32_00785	ENOG4107QPH	glycogen) synthase
FEZ32_00800	ENOG4108URH	decarboxylase
FEZ32_00805	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
FEZ32_00830	ENOG4108Z4U	Ferredoxin
FEZ32_00840	ENOG4107S1E	Beta-lactamase
FEZ32_00845	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FEZ32_00850	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FEZ32_00855	ENOG4107Y80	Major Facilitator superfamily
FEZ32_00880	ENOG4105EF1	ribulokinase
FEZ32_00885	ENOG4108MDK	Dehydrogenase
FEZ32_00895	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
FEZ32_00905	ENOG4107YVI	ribose 5-phosphate isomerase
FEZ32_00910	ENOG4105E98	transcriptional regulator DeoR family
FEZ32_00920	ENOG4105CMT	Dihydroxyacetone kinase
FEZ32_00925	ENOG4105CPQ	Dehydrogenase
FEZ32_00930	ENOG4105C26	Dehydrogenase
FEZ32_00950	ENOG4105DIK	(ABC) transporter
FEZ32_00955	ENOG4105CC5	ABC transporter
FEZ32_00980	ENOG4105E5Q	amino acid AbC transporter
FEZ32_00990	ENOG410848D	S4 domain protein YaaA
FEZ32_01000	ENOG4105D5P	Methylmalonyl-coA mutase
FEZ32_01005	ENOG4105CMN	Methylmalonyl-coA mutase
FEZ32_01025	ENOG4105CPC	Aldo Keto reductase
FEZ32_01065	ENOG4105CSH	Transporter
FEZ32_01085	ENOG4108RWI	nicotinamidase
FEZ32_01090	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FEZ32_01100	ENOG4105BZ1	(ABC) transporter
FEZ32_01115	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
FEZ32_01120	ENOG41084HI	prevent-host-death family
FEZ32_01125	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
FEZ32_01130	ENOG4105C3G	gtp-binding protein
FEZ32_01140	ENOG4105DFM	M18 family aminopeptidase
FEZ32_01150	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FEZ32_01155	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FEZ32_01160	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FEZ32_01170	ENOG4108IAB	Phoh family
FEZ32_01180	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FEZ32_01185	ENOG4105C7Z	Conserved Protein
FEZ32_01200	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FEZ32_01215	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FEZ32_01220	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FEZ32_01255	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FEZ32_01260	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
FEZ32_01270	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FEZ32_01275	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FEZ32_01280	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FEZ32_01295	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FEZ32_01300	ENOG41084BS	50S ribosomal protein L35
FEZ32_01305	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FEZ32_01330	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FEZ32_01375	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FEZ32_01395	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FEZ32_01400	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FEZ32_01405	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FEZ32_01410	ENOG4107U1N	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FEZ32_01425	ENOG41062A4	Transcriptional regulator
FEZ32_01430	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FEZ32_01435	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FEZ32_01440	ENOG4105F8V	Hydrolase, tatD family
FEZ32_01455	ENOG4105C2W	permease
FEZ32_01460	ENOG4107TPY	serine threonine protein kinase
FEZ32_01465	ENOG4107R7A	Allophanate hydrolase subunit 2
FEZ32_01470	ENOG4105E7W	lamb ycsf family protein
FEZ32_01500	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FEZ32_01515	ENOG4108Z6Z	Transcriptional regulator
FEZ32_01545	ENOG4105D9R	oxidoreductase
FEZ32_01560	ENOG41082SX	arsR family transcriptional regulator
FEZ32_01575	ENOG4105C02	permease
FEZ32_01615	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FEZ32_01640	ENOG4107QNK	)-transporter
FEZ32_01650	ENOG4105ETE	Transcriptional regulator (LacI family
FEZ32_01660	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
FEZ32_01665	ENOG4105DH8	myo-inositol catabolism
FEZ32_01675	ENOG4105D7K	pfkb domain protein
FEZ32_01680	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FEZ32_01685	ENOG4105K63	Thioredoxin
FEZ32_01690	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FEZ32_01695	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
FEZ32_01700	ENOG4105CE4	GlcNAc 6-P deacetylase
FEZ32_01705	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FEZ32_01720	ENOG4105C7N	Xanthine uracil vitamin C permease
FEZ32_01735	ENOG4105VEQ	Cold shock protein
FEZ32_01740	ENOG4105C4B	ABC transporter, permease
FEZ32_01745	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FEZ32_01775	ENOG4105ETE	Transcriptional regulator (LacI family
FEZ32_01795	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FEZ32_01800	ENOG4105E4R	Precorrin-3B C17-methyltransferase
FEZ32_01815	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FEZ32_01820	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
FEZ32_01835	ENOG4108UVJ	appr-1-p processing domain protein
FEZ32_01845	ENOG4105K78	MarR family Transcriptional regulator
FEZ32_01850	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FEZ32_01855	ENOG4105CPQ	Dehydrogenase
FEZ32_01860	ENOG4105DRS	transport system, permease
FEZ32_01865	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
FEZ32_01875	ENOG4105DKQ	ROK family
FEZ32_01880	ENOG4105EJQ	L-serine dehydratase
FEZ32_01885	ENOG4108KQ5	Integrase catalytic subunit
FEZ32_01905	ENOG4105C28	cystathionine
FEZ32_01920	ENOG4105C8N	cysteinyl-tRNA synthetase
FEZ32_01930	ENOG4105EQ0	Major Facilitator superfamily
FEZ32_01935	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FEZ32_01950	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FEZ32_01965	ENOG4105DTQ	mandelate racemase muconate lactonizing
FEZ32_01980	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FEZ32_01985	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
FEZ32_01995	ENOG4105DKT	Transcriptional regulator
FEZ32_02000	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FEZ32_02010	ENOG4105DT3	PTS system, galactitol-specific IIc component
FEZ32_02025	ENOG4108VJ1	Transcriptional regulator (CarD family
FEZ32_02040	ENOG4105BZU	Histidine kinase
FEZ32_02045	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FEZ32_02050	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FEZ32_02055	ENOG410849S	phosphocarrier protein (HPr)
FEZ32_02060	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FEZ32_02070	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
FEZ32_02075	ENOG4107QX3	carboxylase
FEZ32_02080	ENOG4107QX3	carboxylase
FEZ32_02085	ENOG4107QSA	Oxaloacetate decarboxylase
FEZ32_02090	ENOG4105NX3	Membrane
FEZ32_02095	ENOG4107RCW	fructose-bisphosphate aldolase
FEZ32_02110	ENOG4105DQR	SNARE associated Golgi
FEZ32_02115	ENOG4108V0P	LemA family
FEZ32_02135	ENOG4108HQS	Glycine betaine
FEZ32_02140	ENOG4108IJ7	Glycine betaine
FEZ32_02145	ENOG4105K5B	UPF0225 protein
FEZ32_02160	ENOG4105CVR	type I restriction-modification system
FEZ32_02170	ENOG4105DZR	Type I site-specific deoxyribonuclease
FEZ32_02180	ENOG4105CVK	Glutamate decarboxylase
FEZ32_02185	ENOG4105K5B	UPF0225 protein
FEZ32_02195	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FEZ32_02205	ENOG4105DRS	transport system, permease
FEZ32_02220	ENOG4105WYW	fructose-bisphosphate aldolase
FEZ32_02230	ENOG4105BZU	Histidine kinase
FEZ32_02235	ENOG4105WH1	Two component transcriptional regulator luxr family
FEZ32_02245	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FEZ32_02250	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FEZ32_02255	ENOG4105C85	amino acid
FEZ32_02260	ENOG4107WGA	YidE YbjL
FEZ32_02265	ENOG4107FQX	Alpha-acetolactate decarboxylase
FEZ32_02275	ENOG4105KNI	merR family transcriptional Regulator
FEZ32_02280	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FEZ32_02285	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FEZ32_02290	ENOG4105CFG	Acts as a chaperone (By similarity)
FEZ32_02310	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FEZ32_02315	ENOG4105BZU	Histidine kinase
FEZ32_02320	ENOG4105EDW	glycosyl transferase, family 39
FEZ32_02320	ENOG4105EDW	glycosyl transferase, family 39
FEZ32_02330	ENOG4105EDW	glycosyl transferase, family 39
FEZ32_02340	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
FEZ32_02355	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FEZ32_02360	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FEZ32_02365	ENOG4107RNR	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA (By similarity)
FEZ32_02370	ENOG4105EAC	phosphoserine phosphatase
FEZ32_02375	ENOG4105DSB	aldose 1-epimerase
FEZ32_02410	ENOG4108JQ7	(ABC) transporter
FEZ32_02435	ENOG4105ETE	Transcriptional regulator (LacI family
FEZ32_02445	ENOG4105FDP	GntR family transcriptional regulator
FEZ32_02475	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FEZ32_02490	ENOG4105C6K	Malic enzyme
FEZ32_02495	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
FEZ32_02505	ENOG4107QNK	)-transporter
FEZ32_02510	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
FEZ32_02515	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
FEZ32_02520	ENOG4105DH8	myo-inositol catabolism
FEZ32_02530	ENOG4105J4Q	Transcriptional regulator
FEZ32_02540	ENOG4105CKV	Membrane
FEZ32_02550	ENOG4105C75	arginyL-tRNA synthetase
FEZ32_02555	ENOG4105CV8	reductase
FEZ32_02560	ENOG4105IE8	Alpha-ketoglutarate permease
FEZ32_02565	ENOG4108UB4	uncharacterized protein ygjQ
FEZ32_02570	ENOG4107RRN	ABC transporter substrate-binding protein
FEZ32_02580	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FEZ32_02585	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FEZ32_02600	ENOG4107QP8	phosphohexose isomerase
FEZ32_02615	ENOG4105CQR	helicase
FEZ32_02640	ENOG4105CPC	Aldo Keto reductase
FEZ32_02645	ENOG41083TI	Protein CrcB homolog
FEZ32_02650	ENOG41085J0	Protein CrcB homolog
FEZ32_02665	ENOG4105D94	Major Facilitator Superfamily
FEZ32_02675	ENOG4108ZJ4	polysaccharide deacetylase
FEZ32_02685	ENOG4105CFH	Aspartokinase
FEZ32_02695	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FEZ32_02700	ENOG4108HCJ	Hydrolase
FEZ32_02705	ENOG410667J	hydrolase
FEZ32_02725	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FEZ32_02730	ENOG41087ID	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FEZ32_02770	ENOG4105CSH	Transporter
FEZ32_02815	ENOG4107YJ4	chain length determinant protein
FEZ32_02820	ENOG4105D3Q	Sugar transferase
FEZ32_02850	ENOG4105PSV	Polysaccharide Biosynthesis Protein
FEZ32_02920	ENOG4105D7W	serine acetyltransferase
FEZ32_02995	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
FEZ32_03030	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
FEZ32_03035	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FEZ32_03045	ENOG4105C59	p-type ATPase
FEZ32_03055	ENOG4105K78	MarR family Transcriptional regulator
FEZ32_03090	ENOG4105D3Q	Sugar transferase
FEZ32_03095	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
FEZ32_03130	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FEZ32_03135	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FEZ32_03145	ENOG4105TV9	FHA Domain-Containing protein
FEZ32_03150	ENOG4105HZM	Fha domain containing protein
FEZ32_03165	ENOG4105CJN	penicillin-binding protein
FEZ32_03175	ENOG4105DDQ	anthranilate synthase
FEZ32_03185	ENOG4105ZJT	Cell division protein CrgA
FEZ32_03215	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
FEZ32_03225	ENOG4107STF	Involved in phosphonate degradation (By similarity)
FEZ32_03250	ENOG4107R1Q	Membrane protein FdrA
FEZ32_03255	ENOG4107REC	cytoplasmic protein
FEZ32_03265	ENOG4105C5B	carbamate kinase
FEZ32_03270	ENOG4107VXZ	Hydrolase
FEZ32_03290	ENOG4108JB8	alcohol dehydrogenase
FEZ32_03325	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FEZ32_03330	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FEZ32_03335	ENOG4108JJ9	ABC, transporter
FEZ32_03340	ENOG4108JJ8	(ABC) transporter
FEZ32_03345	ENOG41080R8	Conserved Protein
FEZ32_03350	ENOG4107QR9	Iron-sulfur cluster binding protein
FEZ32_03355	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FEZ32_03360	ENOG4105DAA	L-lactate
FEZ32_03365	ENOG41073TP	transcriptional regulator
FEZ32_03370	ENOG4105BZ8	glutamate synthase
FEZ32_03375	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
FEZ32_03380	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FEZ32_03395	ENOG410681U	heavy metal transport detoxification protein
FEZ32_03400	ENOG4105VPX	protein, conserved in bacteria
FEZ32_03405	ENOG4105CDU	Replicative dna helicase
FEZ32_03410	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FEZ32_03430	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FEZ32_03440	ENOG4105C94	Transporter
FEZ32_03455	ENOG4105K63	Thioredoxin
FEZ32_03460	ENOG4105C3M	thioredoxin reductase
FEZ32_03480	ENOG4108VX5	3-methyladenine DNA glycosylase
FEZ32_03490	ENOG4105CQ7	ATP-dependent helicase
FEZ32_03505	ENOG4105KHC	sulfurtransferase
FEZ32_03530	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FEZ32_03535	ENOG4105E2K	Glycosyl transferase (Group 1
FEZ32_03545	ENOG4108IJ1	Dehydrogenase
FEZ32_03550	ENOG4105CDA	abc transporter atp-binding protein
FEZ32_03555	ENOG4107UBR	Extracellular solute-binding protein family 3
FEZ32_03560	ENOG4108Q1T	ABC transporter
FEZ32_03565	ENOG4105DRP	amino acid AbC transporter
FEZ32_03570	ENOG4105DE4	1-phosphofructokinase
FEZ32_03600	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FEZ32_03645	ENOG4105BZ4	penicillin-binding protein
FEZ32_03680	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FEZ32_03690	ENOG4105C28	cystathionine
FEZ32_03700	ENOG4106A3M	Cytochrome p-450
FEZ32_03715	ENOG4105CVN	desaturase
FEZ32_03735	ENOG4105EWK	phytoene
FEZ32_03740	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FEZ32_03760	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FEZ32_03765	ENOG4108IRC	dna polymerase iii
FEZ32_03785	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
FEZ32_03795	ENOG4105C59	p-type ATPase
FEZ32_03805	ENOG4107R16	Multicopper oxidase
FEZ32_03810	ENOG41062D9	Histidine kinase
FEZ32_03815	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FEZ32_03845	ENOG4105DCF	alanine dehydrogenase
FEZ32_03850	ENOG4108MGF	sugar kinase
FEZ32_03890	ENOG4107QRT	dEAD DEAH box helicase
FEZ32_03900	ENOG4105C0D	helicase
FEZ32_03915	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
FEZ32_03925	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
FEZ32_03935	ENOG4107ZYJ	bioY protein
FEZ32_03950	ENOG4105F8D	glycoside hydrolase family 4
FEZ32_03955	ENOG4105CSR	polyphosphate kinase 2
FEZ32_03960	ENOG4105DZW	Dipeptidase
FEZ32_03975	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
FEZ32_03985	ENOG4105CH6	catalase
FEZ32_04005	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FEZ32_04045	ENOG4105Y3U	Transglycosylase-associated protein
FEZ32_04050	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FEZ32_04055	ENOG4105CSH	Transporter
FEZ32_04065	ENOG41086KC	Transcriptional regulator
FEZ32_04075	ENOG4105Y3U	Transglycosylase-associated protein
FEZ32_04080	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FEZ32_04085	ENOG4107Y5I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FEZ32_04090	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
FEZ32_04095	ENOG4105CSH	Transporter
FEZ32_04100	ENOG4105DWF	phosphomethylpyrimidine kinase
FEZ32_04105	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FEZ32_04110	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FEZ32_04115	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FEZ32_04120	ENOG4107YH6	single-stranded DNA-binding protein
FEZ32_04125	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
FEZ32_04130	ENOG4105DBE	peroxidase
FEZ32_04160	ENOG4108IXY	short-chain dehydrogenase reductase
FEZ32_04190	ENOG4105M0C	cytoplasmic protein
FEZ32_04200	ENOG4105CQB	FAD linked oxidase domain protein
FEZ32_04210	ENOG4105WH1	Two component transcriptional regulator luxr family
FEZ32_04220	ENOG4105CJ1	ABC, transporter
FEZ32_04230	ENOG4105BZU	Histidine kinase
FEZ32_04235	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FEZ32_04240	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
FEZ32_04245	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
FEZ32_04250	ENOG4108JQ1	Dehydrogenase
FEZ32_04305	ENOG4107R73	Mate efflux family protein
FEZ32_04315	ENOG4108TFM	Kinase, PfkB family
FEZ32_04320	ENOG4108Z66	YbaK ebsC protein
FEZ32_04335	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
FEZ32_04345	ENOG4105D7K	pfkb domain protein
FEZ32_04360	ENOG4105CUC	YeeE YedE family protein
FEZ32_04370	ENOG4105IDI	abc transporter atp-binding protein
FEZ32_04375	ENOG4108QVN	serine threonine protein kinase
FEZ32_04385	ENOG4105CTQ	phosphohexokinase
FEZ32_04390	ENOG4105E5G	Alpha beta hydrolase fold
FEZ32_04395	ENOG4105BZU	Histidine kinase
FEZ32_04400	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FEZ32_04410	ENOG4107RCV	ABC transporter, permease
FEZ32_04415	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FEZ32_04420	ENOG4105CXY	transporter
FEZ32_04450	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FEZ32_04470	ENOG4105CAG	UPF0210 protein
FEZ32_04485	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FEZ32_04500	ENOG4105D8X	mechanosensitive ion channel
FEZ32_04505	ENOG4105BZW	Glycerate kinase
FEZ32_04510	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FEZ32_04525	ENOG4105D9P	serine threonine protein kinase
FEZ32_04540	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FEZ32_04545	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FEZ32_04570	ENOG4105D3G	Pseudouridine synthase
FEZ32_04575	ENOG4105K63	Thioredoxin
FEZ32_04600	ENOG4105CSV	Glutaminase
FEZ32_04620	ENOG4108XG2	Histidine kinase
FEZ32_04635	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
FEZ32_04640	ENOG4105FDP	GntR family transcriptional regulator
FEZ32_04650	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FEZ32_04655	ENOG4105CPF	Cell wall formation (By similarity)
FEZ32_04665	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FEZ32_04675	ENOG4105FA0	parb-like partition protein
FEZ32_04680	ENOG4107QJE	Chromosome Partitioning Protein
FEZ32_04685	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FEZ32_04695	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FEZ32_04710	ENOG41084CH	50S ribosomal protein l34
FEZ32_04715	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FEZ32_04720	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FEZ32_04725	ENOG4107R34	abc transporter permease protein
FEZ32_04730	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FEZ32_04740	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FEZ32_04745	ENOG4105K7N	UPF0232 protein
FEZ32_04750	ENOG4105EIP	mannose-6-phosphate isomerase
FEZ32_04765	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FEZ32_04770	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FEZ32_04775	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
FEZ32_04780	ENOG4105EMD	TRANSCRIPTIONal
FEZ32_04795	ENOG4105JF0	Phosphoenolpyruvate-dependent sugar phosphotransferase system, eiia 2
FEZ32_04800	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
FEZ32_04805	ENOG4105D9R	oxidoreductase
FEZ32_04810	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FEZ32_04830	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FEZ32_04845	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FEZ32_04855	ENOG4105YVS	arsR family transcriptional regulator
FEZ32_04865	ENOG4105CMQ	Chloride channel
FEZ32_04870	ENOG4105C2C	drug resistance transporter, Bcr CflA
FEZ32_04920	ENOG4105EBR	Carboxylesterase
FEZ32_04925	ENOG4105CHM	Aminotransferase
FEZ32_04930	ENOG41090U3	tautomerase
FEZ32_04935	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FEZ32_04945	ENOG4105YHU	PTS system
FEZ32_04955	ENOG4105ETZ	PTS System
FEZ32_04960	ENOG4105F3R	pts system mannose fructose sorbose family iid
FEZ32_04965	ENOG4108KP7	hydrolase
FEZ32_04985	ENOG4105DVE	abc transporter atp-binding protein
FEZ32_04990	ENOG4108TZY	GntR Family Transcriptional Regulator
FEZ32_04995	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
FEZ32_05000	ENOG4105E5Q	amino acid AbC transporter
FEZ32_05005	ENOG4105CDA	abc transporter atp-binding protein
FEZ32_05010	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FEZ32_05045	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
FEZ32_05055	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
FEZ32_05060	ENOG4105W4R	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
FEZ32_05065	ENOG4108V4M	Cobalt abc transporter
FEZ32_05070	ENOG4108JJB	ABC transporter
FEZ32_05075	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
FEZ32_05080	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FEZ32_05085	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FEZ32_05090	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FEZ32_05100	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
FEZ32_05105	ENOG4108YZT	Adenosylcobinamide kinase
FEZ32_05130	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
FEZ32_05185	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FEZ32_05190	ENOG4105CXT	aspartate transcarbamylase
FEZ32_05195	ENOG4105CTZ	aminopeptidase c
FEZ32_05200	ENOG41064HX	Suppressor of fused protein (SUFU)
FEZ32_05205	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FEZ32_05210	ENOG4105C9Q	fumarate hydratase class II
FEZ32_05275	ENOG4105C26	Dehydrogenase
FEZ32_05280	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
FEZ32_05290	ENOG4105WYW	fructose-bisphosphate aldolase
FEZ32_05300	ENOG4105BZU	Histidine kinase
FEZ32_05310	ENOG4108M15	ABC transporter
FEZ32_05315	ENOG4105CKU	formyltetrahydrofolate synthetase
FEZ32_05340	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FEZ32_05345	ENOG4105WH1	Two component transcriptional regulator luxr family
FEZ32_05350	ENOG4105BZU	Histidine kinase
FEZ32_05360	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
FEZ32_05370	ENOG4105EYF	MMPL domain protein
FEZ32_05380	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FEZ32_05385	ENOG4105C6K	Malic enzyme
FEZ32_05415	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
FEZ32_05425	ENOG4105CD5	CoA-binding domain protein
FEZ32_05440	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FEZ32_05450	ENOG4105CTQ	phosphohexokinase
FEZ32_05460	ENOG4105CEI	nitrite reductase
FEZ32_05480	ENOG4105C0H	protease
FEZ32_05505	ENOG4105CXK	mandelate racemase muconate lactonizing
FEZ32_05520	ENOG4105CHF	Glutathione S-transferase
FEZ32_05545	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FEZ32_05550	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FEZ32_05575	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
FEZ32_05585	ENOG41062D9	Histidine kinase
FEZ32_05605	ENOG4105BZ1	(ABC) transporter
FEZ32_05610	ENOG4105BZ1	(ABC) transporter
FEZ32_05625	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
FEZ32_05630	ENOG4105DRS	transport system, permease
FEZ32_05635	ENOG4105CG3	alpha amylase, catalytic region
FEZ32_05645	ENOG4105KT7	mgtC SapB transporter
FEZ32_05650	ENOG4105CJQ	hydrolase, family 31
FEZ32_05655	ENOG4105NYY	transcriptional regulator, RpiR
FEZ32_05725	ENOG4105CPP	Dehydrogenase, E1 component
FEZ32_05730	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
FEZ32_05740	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FEZ32_05750	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FEZ32_05755	ENOG4105CQC	Prephenate dehydratase
FEZ32_05760	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FEZ32_05785	ENOG4108KP7	hydrolase
FEZ32_05825	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
FEZ32_05830	ENOG4105ETE	Transcriptional regulator (LacI family
FEZ32_05835	ENOG4108RCF	TRANSCRIPTIONal
FEZ32_05855	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
FEZ32_05860	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
FEZ32_05875	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FEZ32_05885	ENOG4108Z6B	deaminase
FEZ32_05920	ENOG4105FQP	Beta-lactamase
FEZ32_05930	ENOG4105E90	ABC transporter
FEZ32_05940	ENOG4108IJ8	ABC transporter
FEZ32_05945	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
FEZ32_05960	ENOG4105C87	Aminotransferase class I and II
FEZ32_05970	ENOG4105K6T	rare lipoprotein A
FEZ32_05975	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FEZ32_05980	ENOG4105ETE	Transcriptional regulator (LacI family
FEZ32_05985	ENOG4105C2J	ABC transporter
FEZ32_05990	ENOG4105CNN	ABC, transporter
FEZ32_05995	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
FEZ32_06000	ENOG4108RVA	ribokinase
FEZ32_06005	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
FEZ32_06030	ENOG4108SU4	UPF0309 protein
FEZ32_06040	ENOG4105WS7	Cation transport regulator
FEZ32_06045	ENOG4107S2Z	UPF0761 membrane protein
FEZ32_06065	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
FEZ32_06075	ENOG4105DQE	DNA ligase
FEZ32_06115	ENOG4105DJ2	Major Facilitator Superfamily
FEZ32_06160	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FEZ32_06165	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FEZ32_06170	ENOG4107Z1W	Fructose transport system kinase
FEZ32_06175	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FEZ32_06195	ENOG4105D1Q	UPF0246 protein
FEZ32_06205	ENOG4108JQ7	(ABC) transporter
FEZ32_06210	ENOG4105C3U	ABC transporter
FEZ32_06215	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FEZ32_06240	ENOG4105CAT	Cytidine monophosphate kinase
FEZ32_06300	ENOG4105DIN	metallophosphoesterase
FEZ32_06305	ENOG4105BZ4	penicillin-binding protein
FEZ32_06325	ENOG4105IJJ	transcriptional regulator, crp fnr family
FEZ32_06335	ENOG4107QX9	Thiol disulfide interChange protein
FEZ32_06390	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FEZ32_06395	ENOG4108I5C	dEAD DEAH box helicase
FEZ32_06400	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FEZ32_06410	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FEZ32_06420	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FEZ32_06425	ENOG4105C6E	dna polymerase iii
FEZ32_06435	ENOG4105MA4	psp1 domain protein
FEZ32_06440	ENOG4106JDR	secreted
FEZ32_06485	ENOG4105CPQ	Dehydrogenase
FEZ32_06510	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FEZ32_06530	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FEZ32_06535	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FEZ32_06550	ENOG4105EW9	transcriptional regulator AsnC family
FEZ32_06595	ENOG4105I82	acetyl xylan esterase
FEZ32_06605	ENOG4105F0N	pyrophosphate phospho-hydrolase
FEZ32_06615	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FEZ32_06630	ENOG4105EUJ	GTP cyclohydrolase i
FEZ32_06645	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FEZ32_06665	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FEZ32_06720	ENOG4108I5D	sulfate abc transporter
FEZ32_06725	ENOG4108UCS	ABC, transporter
FEZ32_06735	ENOG4105C54	Major Facilitator superfamily
FEZ32_06740	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FEZ32_06745	ENOG4105ETE	Transcriptional regulator (LacI family
FEZ32_06750	ENOG4105CH6	catalase
FEZ32_06760	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FEZ32_06765	ENOG4105D52	delta-aminolevulinic acid dehydratase
FEZ32_06775	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FEZ32_06785	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FEZ32_06790	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FEZ32_06795	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FEZ32_06810	ENOG4105VMP	Transcriptional regulator
FEZ32_06825	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FEZ32_06835	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
FEZ32_06855	ENOG4105II7	pyrroline-5-carboxylate reductase
FEZ32_06870	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FEZ32_06875	ENOG4108RH7	phosphoglycerate mutase
FEZ32_06880	ENOG4107ZT5	Thiol disulfide interchange protein
FEZ32_06885	ENOG4107QIV	Cytochrome c biogenesis protein
FEZ32_06895	ENOG4105CRE	cytochrome C
FEZ32_06905	ENOG4105EMU	Dehydrogenase
FEZ32_06915	ENOG4105C7B	Threonine dehydratase
FEZ32_06940	ENOG4105E0A	ABC, transporter
FEZ32_06945	ENOG4108IHU	transport system permease protein
FEZ32_06950	ENOG4105DQ5	transport system permease protein
FEZ32_06955	ENOG4108MES	Periplasmic binding protein
FEZ32_06960	ENOG4105BZ1	(ABC) transporter
FEZ32_06965	ENOG4105BZ1	(ABC) transporter
FEZ32_06970	ENOG41068HZ	50S ribosomal protein L32
FEZ32_06975	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FEZ32_06980	ENOG4105W0E	50S ribosomal protein L33
FEZ32_06985	ENOG4105NRA	50s ribosomal protein l31 type b
FEZ32_06990	ENOG4105KDC	50s ribosomal protein l28
FEZ32_06995	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FEZ32_07010	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
FEZ32_07020	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FEZ32_07025	ENOG4107NHD	transcriptional regulator
FEZ32_07045	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FEZ32_07055	ENOG4108SVG	May play a role in the intracellular transport of hydrophobic ligands
FEZ32_07060	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
FEZ32_07080	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FEZ32_07085	ENOG4105CI3	gtp-binding protein typa
FEZ32_07090	ENOG4105DXB	Major Facilitator superfamily
FEZ32_07125	ENOG4106KNT	transcriptional regulator
FEZ32_07150	ENOG4106KNT	transcriptional regulator
FEZ32_07155	ENOG4105CNT	hydrolase family 2
FEZ32_07205	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
FEZ32_07215	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
FEZ32_07220	ENOG4105XTG	Pfam:DUF156
FEZ32_07235	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FEZ32_07240	ENOG4108RNG	Permease of the drug metabolite transporter
FEZ32_07250	ENOG4105C83	adenylosuccinate lyase
FEZ32_07255	ENOG4105C5Q	Transcriptional regulator
FEZ32_07260	ENOG4108JU3	Alkyl hydroperoxide reductase
FEZ32_07265	ENOG4105D3R	alkyl hydroperoxide reductase
FEZ32_07270	ENOG4105C8V	SAICAR synthetase
FEZ32_07275	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
FEZ32_07285	ENOG4105HDK	L-asparaginase
FEZ32_07295	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FEZ32_07305	ENOG4108KQ5	Integrase catalytic subunit
FEZ32_07310	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
FEZ32_07330	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FEZ32_07340	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FEZ32_07345	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FEZ32_07370	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
FEZ32_07375	ENOG4105C32	Amino acid ABC transporter (Permease)
FEZ32_07380	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
FEZ32_07385	ENOG4105C0Z	ABC transporter
FEZ32_07390	ENOG4108IV0	ABC, transporter
FEZ32_07480	ENOG4108HE4	integrase family
FEZ32_07505	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FEZ32_07510	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
FEZ32_07540	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
FEZ32_07545	ENOG4106V2I	dimethylaminohydrolase
FEZ32_07550	ENOG4105CUB	amino acid
FEZ32_07590	ENOG4105VDH	Dihydroxyacetone kinase
FEZ32_07595	ENOG4108UTZ	Dihydroxyacetone kinase
FEZ32_07600	ENOG4105CMT	Dihydroxyacetone kinase
FEZ32_07605	ENOG4107SFI	Major Facilitator superfamily
FEZ32_07615	ENOG41067V3	Antibiotic biosynthesis monooxygenase
FEZ32_07620	ENOG4105BZ1	(ABC) transporter
FEZ32_07630	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FEZ32_07655	ENOG4105E4F	Isochorismate synthase
FEZ32_07660	ENOG4105P52	geranylgeranyl reductase
FEZ32_07670	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FEZ32_07675	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FEZ32_07680	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FEZ32_07690	ENOG4107QIZ	NADH dehydrogenase
FEZ32_07695	ENOG4108IEH	NADH dehydrogenase subunit g
FEZ32_07700	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FEZ32_07705	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FEZ32_07710	ENOG4105DF2	NADH dehydrogenase subunit j
FEZ32_07715	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FEZ32_07730	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FEZ32_07740	ENOG4105CPD	ethanolamine ammonia-lyase
FEZ32_07745	ENOG4107FQ9	ethanolamine ammonia-lyase
FEZ32_07750	ENOG4105CI0	Citrate lyase
FEZ32_07755	ENOG4105C9K	Endothelin-converting enzyme 1
FEZ32_07765	ENOG4105DQU	oxidoreductase, subunit beta
FEZ32_07770	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
FEZ32_07780	ENOG4105CGU	Enoyl-CoA hydratase
FEZ32_07785	ENOG4105CGK	Exodeoxyribonuclease III
FEZ32_07795	ENOG4108VPT	UPF0234 protein
FEZ32_07815	ENOG4105WDJ	50S ribosomal protein L33
FEZ32_07820	ENOG410900P	UPF0336 protein
FEZ32_07830	ENOG4107R4N	Cell wall formation (By similarity)
FEZ32_07835	ENOG4105XT2	Transcriptional regulator
FEZ32_07850	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FEZ32_07855	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FEZ32_07860	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FEZ32_07865	ENOG4108VZM	50s ribosomal protein L10
FEZ32_07870	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FEZ32_07875	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FEZ32_07880	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FEZ32_07885	ENOG4105EE0	oxidoreductase
FEZ32_07890	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FEZ32_07895	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FEZ32_07900	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FEZ32_07905	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FEZ32_07920	ENOG4105CGH	5'-nucleotidase
FEZ32_07925	ENOG4105CX6	glutaminyL-tRNA synthetase
FEZ32_07930	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FEZ32_07935	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FEZ32_07940	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FEZ32_07945	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FEZ32_07950	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FEZ32_07955	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FEZ32_07960	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FEZ32_07965	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FEZ32_07970	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FEZ32_07975	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FEZ32_07980	ENOG41082SA	50s ribosomal protein l29
FEZ32_07985	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FEZ32_08000	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FEZ32_08005	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FEZ32_08010	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FEZ32_08015	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FEZ32_08020	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FEZ32_08025	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FEZ32_08030	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FEZ32_08035	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FEZ32_08040	ENOG410849U	50S ribosomal protein L30
FEZ32_08045	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FEZ32_08080	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FEZ32_08100	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FEZ32_08105	ENOG41067V7	50S ribosomal protein L36
FEZ32_08115	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FEZ32_08120	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FEZ32_08125	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FEZ32_08130	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FEZ32_08135	ENOG4108ZT0	50S ribosomal protein l17
FEZ32_08140	ENOG4108MJN	Glycosyl Transferase
FEZ32_08155	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FEZ32_08165	ENOG4108JJB	ABC transporter
FEZ32_08175	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
FEZ32_08180	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FEZ32_08185	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FEZ32_08190	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FEZ32_08195	ENOG4108UJD	30S ribosomal protein S9
FEZ32_08200	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FEZ32_08210	ENOG4105CS9	pantothenic acid kinase
FEZ32_08215	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FEZ32_08220	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FEZ32_08225	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
FEZ32_08230	ENOG4105E2R	ROK family
FEZ32_08245	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
FEZ32_08265	ENOG4105C1J	atp-dependent rna helicase
FEZ32_08270	ENOG4108097	ATP-binding protein
FEZ32_08280	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
FEZ32_08285	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FEZ32_08330	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FEZ32_08335	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FEZ32_08340	ENOG41072RD	Membrane
FEZ32_08345	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FEZ32_08360	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FEZ32_08365	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
FEZ32_08370	ENOG4105D7W	serine acetyltransferase
FEZ32_08375	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FEZ32_08400	ENOG4105WH1	Two component transcriptional regulator luxr family
FEZ32_08405	ENOG4105Y3U	Transglycosylase-associated protein
FEZ32_08410	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FEZ32_08415	ENOG4108UMI	ABC transporter, permease
FEZ32_08420	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FEZ32_08425	ENOG4105D01	(LipO)protein
FEZ32_08440	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FEZ32_08470	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FEZ32_08475	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FEZ32_08485	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FEZ32_08500	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FEZ32_08510	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FEZ32_08535	ENOG4107TFB	basic membrane
FEZ32_08540	ENOG4108JQ9	ABC transporter
FEZ32_08545	ENOG4105UIB	(ABC) transporter
FEZ32_08565	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FEZ32_08580	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
FEZ32_08595	ENOG4108JIK	carboxylase
FEZ32_08605	ENOG4105DWF	phosphomethylpyrimidine kinase
FEZ32_08610	ENOG4105EMU	Dehydrogenase
FEZ32_08615	ENOG4105CEU	Arginine dihydrolase
FEZ32_08625	ENOG4107WR6	Maf-like protein
FEZ32_08635	ENOG4105D8K	carboxyl transferase
FEZ32_08640	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FEZ32_08645	ENOG4105EC3	peptidase S51, dipeptidase E
FEZ32_08665	ENOG4108KGH	TRANSCRIPTIONal
FEZ32_08690	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
FEZ32_08725	ENOG41076HS	cation diffusion facilitator family transporter
FEZ32_08730	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FEZ32_08760	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FEZ32_08775	ENOG4105CE1	Ferrous iron transport protein b
FEZ32_08785	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FEZ32_08790	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FEZ32_08795	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FEZ32_08800	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FEZ32_08805	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
FEZ32_08810	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FEZ32_08895	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FEZ32_08930	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FEZ32_08945	ENOG4105C0B	DNA polymerase III (alpha subunit)
FEZ32_08970	ENOG4105CUB	amino acid
FEZ32_08975	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FEZ32_08990	ENOG4105C85	amino acid
FEZ32_08995	ENOG4107RPQ	ABC transporter
FEZ32_09000	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
FEZ32_09010	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
FEZ32_09060	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
FEZ32_09100	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
FEZ32_09130	ENOG4105DFD	Na H antiporter
FEZ32_09135	ENOG4105CEU	Arginine dihydrolase
FEZ32_09140	ENOG4105D5Q	Arginine ornithine antiporter
FEZ32_09170	ENOG4105CQB	FAD linked oxidase domain protein
FEZ32_09185	ENOG4108IQE	Amp-dependent synthetase and ligase
FEZ32_09200	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
FEZ32_09215	ENOG4105MC2	DSBA oxidoreductase
FEZ32_09220	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FEZ32_09235	ENOG4108YZG	isomerase
FEZ32_09255	ENOG4105CRK	lysyL-tRNA synthetase
FEZ32_09275	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FEZ32_09280	ENOG4105DSF	transport protein
FEZ32_09285	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FEZ32_09290	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FEZ32_09295	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FEZ32_09300	ENOG4107RE3	peptidase, S41
FEZ32_09310	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FEZ32_09320	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
FEZ32_09335	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FEZ32_09345	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
FEZ32_09355	ENOG4105CJ1	ABC, transporter
FEZ32_09360	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FEZ32_09365	ENOG4105ETE	Transcriptional regulator (LacI family
FEZ32_09370	ENOG4105EG2	ABC transporter, permease
FEZ32_09375	ENOG4105D56	permease protein
FEZ32_09390	ENOG4105DIW	FeS assembly protein SUFB
FEZ32_09405	ENOG4105C3K	feS assembly ATPase SufC
FEZ32_09410	ENOG4105C9B	Cysteine desulfurase
FEZ32_09415	ENOG4108UNV	SUF system FeS assembly protein, NifU family
FEZ32_09450	ENOG4105C5H	ABC transporter
FEZ32_09475	ENOG4105CHR	reductase
FEZ32_09485	ENOG4108IJ0	Aspartate ammonia-lyase
FEZ32_09495	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FEZ32_09500	ENOG4105DKW	ABC transporter
FEZ32_09515	ENOG4105DHU	Bile acid
FEZ32_09545	ENOG4108JQ7	(ABC) transporter
FEZ32_09555	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FEZ32_09565	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FEZ32_09570	ENOG4105E4C	Lytic transglycosylase catalytic
FEZ32_09575	ENOG4105CE9	30S ribosomal protein S2
FEZ32_09580	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FEZ32_09585	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FEZ32_09590	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FEZ32_09595	ENOG4105KNE	Phosphatidate cytidylyltransferase
FEZ32_09600	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FEZ32_09610	ENOG4105DZP	Membrane-associated zinc metalloprotease
FEZ32_09615	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FEZ32_09640	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FEZ32_09655	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
FEZ32_09670	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FEZ32_09675	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FEZ32_09680	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FEZ32_09690	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FEZ32_09710	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FEZ32_09730	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FEZ32_09740	ENOG4105C7K	acetolactate synthase
FEZ32_09750	ENOG4105CN5	Metallo-Beta-Lactamase
FEZ32_09755	ENOG4105VB9	50S ribosomal protein l28
FEZ32_09760	ENOG4105CB5	ATP-dependent DNA helicase recG
FEZ32_09770	ENOG4106H78	methyltransferase
FEZ32_09775	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FEZ32_09790	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FEZ32_09795	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FEZ32_09815	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
FEZ32_09850	ENOG4105K5M	30s ribosomal protein S16
FEZ32_09855	ENOG41082KU	UPF0109 protein
FEZ32_09860	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FEZ32_09865	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FEZ32_09880	ENOG4105E33	succinate dehydrogenase
FEZ32_09890	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FEZ32_09895	ENOG4107QYR	Signal peptidase i
FEZ32_09900	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FEZ32_09910	ENOG41080R2	UPF0102 protein
FEZ32_09915	ENOG4105C0P	Mg chelatase subunit ChlI
FEZ32_09985	ENOG4105BZU	Histidine kinase
FEZ32_09990	ENOG4105ETX	regulatoR
FEZ32_09995	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FEZ32_10005	ENOG4105C4B	ABC transporter, permease
FEZ32_10045	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FEZ32_10055	ENOG4105CPC	Aldo Keto reductase
FEZ32_10070	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
FEZ32_10075	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FEZ32_10110	ENOG4105DSU	hydrolase
FEZ32_10115	ENOG4105VKD	bioY protein
FEZ32_10120	ENOG4108JJB	ABC transporter
FEZ32_10130	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FEZ32_10135	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FEZ32_10140	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FEZ32_10145	ENOG4108YZ4	nudix hydrolase
FEZ32_10150	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FEZ32_10170	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FEZ32_10175	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
FEZ32_10185	ENOG4107TMB	Transcriptional regulator
FEZ32_10210	ENOG4105CQR	helicase
FEZ32_10215	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FEZ32_10220	ENOG4105K59	histidine triad (HIT) protein
FEZ32_10235	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FEZ32_10245	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FEZ32_10250	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FEZ32_10255	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FEZ32_10265	ENOG4105ERH	Fumarylacetoacetate hydrolase
FEZ32_10270	ENOG4107FCW	Abortive infection protein
FEZ32_10285	ENOG41069M3	Transcriptional regulator
FEZ32_10290	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FEZ32_10295	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FEZ32_10305	ENOG4105CPF	Cell wall formation (By similarity)
FEZ32_10325	ENOG4107QZI	cell division protein FtsK
FEZ32_10345	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
FEZ32_10350	ENOG4105CAK	Cell division ATP-binding protein ftsE
FEZ32_10360	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FEZ32_10365	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FEZ32_10370	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
FEZ32_10375	ENOG4105CAS	nag kinase
FEZ32_10380	ENOG4105C8Y	Acetylornithine aminotransferase
FEZ32_10390	ENOG4105CH7	arginosuccinase
FEZ32_10415	ENOG4108Z7F	N-acetyltransferase
FEZ32_10420	ENOG4108UJU	UPF0301 protein
FEZ32_10425	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FEZ32_10430	ENOG4105BZU	Histidine kinase
FEZ32_10435	ENOG4105G3P	Lipoprotein lpqB
FEZ32_10445	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
FEZ32_10455	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FEZ32_10475	ENOG4105C7I	Dehydrogenase
FEZ32_10485	ENOG4105C31	Tryptophanyl-tRNA synthetase
FEZ32_10515	ENOG4105VEQ	Cold shock protein
FEZ32_10520	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
FEZ32_10545	ENOG4107QKA	exodeoxyribonuclease V beta
FEZ32_10575	ENOG41063PX	domain protein
FEZ32_10585	ENOG4105DJZ	UPF0182 protein
FEZ32_10590	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
FEZ32_10620	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FEZ32_10630	ENOG4108JQ7	(ABC) transporter
FEZ32_10635	ENOG4108JQ1	Dehydrogenase
FEZ32_10640	ENOG4107TK4	histidinol-phosphate phosphatase
FEZ32_10655	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FEZ32_10665	ENOG4105EMN	RNA polymerase sigma factor
FEZ32_10690	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
FEZ32_10700	ENOG4108URH	decarboxylase
FEZ32_10715	ENOG4105D6E	homoserine dehydrogenase
FEZ32_10720	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FEZ32_10730	ENOG4105VFB	Binds the 23S rRNA (By similarity)
FEZ32_10735	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FEZ32_10740	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FEZ32_10750	ENOG4105ESV	Glycosyl transferase, family 4
FEZ32_10820	ENOG4105CEY	Amp-dependent synthetase and ligase
FEZ32_10830	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
FEZ32_10840	ENOG4105CAQ	asparagine synthetase
FEZ32_10845	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FEZ32_10865	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
FEZ32_10870	ENOG4105ZA1	atp synthase
FEZ32_10875	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FEZ32_10880	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FEZ32_10885	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FEZ32_10890	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FEZ32_10895	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FEZ32_10900	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FEZ32_10915	ENOG4105EV9	Alpha Beta Hydrolase
FEZ32_10925	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
FEZ32_10970	ENOG4105C22	threonyL-tRNA synthetase
FEZ32_10980	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
FEZ32_10985	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
FEZ32_10990	ENOG4105E2K	Glycosyl transferase (Group 1
FEZ32_11010	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FEZ32_11015	ENOG4108UW8	fha domain-containing protein
FEZ32_11035	ENOG4107H3J	ribonuclease
FEZ32_11040	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
FEZ32_11050	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
FEZ32_11055	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FEZ32_11060	ENOG4107TE5	Lipid kinase
FEZ32_11065	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
FEZ32_11070	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FEZ32_11080	ENOG4105CN5	Metallo-Beta-Lactamase
FEZ32_11085	ENOG4105CFG	Acts as a chaperone (By similarity)
FEZ32_11115	ENOG4105CUB	amino acid
FEZ32_11130	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FEZ32_11135	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
FEZ32_11140	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
FEZ32_11145	ENOG4105Q70	
FEZ32_11150	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
FEZ32_11155	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FEZ32_11165	ENOG4105DWV	Homoserine O-trans-acetylase
FEZ32_11170	ENOG4105DWV	Homoserine O-trans-acetylase
FEZ32_11175	ENOG4105CYC	Transferase
FEZ32_11185	ENOG410667J	hydrolase
FEZ32_11285	ENOG4105C6T	cysteine synthase
FEZ32_11305	ENOG4105C8Y	Acetylornithine aminotransferase
FEZ32_11315	ENOG4105C7K	acetolactate synthase
FEZ32_11350	ENOG4107QUV	Domain protein
FEZ32_11355	ENOG4105JAB	phenazine biosynthesis protein, phzf family
FEZ32_11460	ENOG4108Z9K	Osmotically inducible protein
FEZ32_11475	ENOG4105CAT	Cytidine monophosphate kinase
FEZ32_11485	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
FEZ32_11490	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
FEZ32_11505	ENOG4105C3R	Methionine synthase
FEZ32_11515	ENOG4105DJV	ribulose-phosphate 3-epimerase
FEZ32_11525	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FEZ32_11545	ENOG4107QRT	dEAD DEAH box helicase
FEZ32_11550	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FEZ32_11560	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FEZ32_11565	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FEZ32_11575	ENOG410803B	Involved in the transcription termination process (By similarity)
FEZ32_11580	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FEZ32_11590	ENOG4105D49	3-dehydroquinate synthase
FEZ32_11600	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FEZ32_11605	ENOG4105E2X	shikimate dehydrogenase
FEZ32_11615	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FEZ32_11620	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FEZ32_11650	ENOG4105C9M	aspartyl-trna synthetase
FEZ32_11660	ENOG4107MVR	Transcriptional regulator
FEZ32_11665	ENOG4105CIZ	coA-substrate-specific enzyme activase
FEZ32_11670	ENOG4105PGM	cation diffusion facilitator family transporter
FEZ32_11680	ENOG4105CUT	histidyl-tRNA synthetase
FEZ32_11690	ENOG4105C99	atpase involved in dna repair
FEZ32_11695	ENOG4105D98	threonine synthase
FEZ32_11700	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FEZ32_11710	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FEZ32_11715	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FEZ32_11720	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FEZ32_11730	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FEZ32_11735	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FEZ32_11740	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FEZ32_11745	ENOG4105CDY	transcriptional regulatory protein
FEZ32_11750	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FEZ32_11755	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FEZ32_11760	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FEZ32_11765	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FEZ32_11770	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FEZ32_11800	ENOG4105CBC	glutamate synthase
FEZ32_11805	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FEZ32_11810	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FEZ32_11815	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FEZ32_11820	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FEZ32_11835	ENOG4105CRQ	synthase (Component I)
FEZ32_11840	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FEZ32_11855	ENOG4105C2W	permease
FEZ32_11860	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FEZ32_11865	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FEZ32_11870	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FEZ32_11895	ENOG4105E2Y	ABC, transporter
FEZ32_11910	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FEZ32_11930	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
FEZ32_11935	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
FEZ32_11940	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FEZ32_11965	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
FEZ32_11970	ENOG4108HKT	sucrose-6-phosphate hydrolase
FEZ32_12000	ENOG4105E0X	reductase
FEZ32_12015	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FEZ32_12020	ENOG4107QM5	aconitate hydratase
FEZ32_12025	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FEZ32_12030	ENOG4105C0X	amino acid
FEZ32_12035	ENOG4107VEG	TrkA-N domain protein
FEZ32_12055	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FEZ32_12090	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FEZ32_12110	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FEZ32_12125	ENOG4105E2D	ec 3.2.1.52
FEZ32_12130	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FEZ32_12140	ENOG4105C29	acyl-CoA thioesterase
FEZ32_12145	ENOG4105CT8	Phosphorylase
FEZ32_12150	ENOG4105CQ7	ATP-dependent helicase
FEZ32_12170	ENOG4105DHP	deoxycytidine triphosphate deaminase
FEZ32_12175	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FEZ32_12180	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FEZ32_12195	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FEZ32_12200	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FEZ32_12205	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FEZ32_12215	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FEZ32_12220	ENOG4107WI4	Aldose-1-epimerase
FEZ32_12225	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FEZ32_12230	ENOG4105KC9	Modulates RecA activity (By similarity)
FEZ32_12235	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FEZ32_12245	ENOG4105E98	transcriptional regulator DeoR family
FEZ32_12255	ENOG4105CEV	competence damage-inducible protein
FEZ32_12265	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
FEZ32_12275	ENOG4107T52	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FEZ32_12280	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FEZ32_12285	ENOG4107TYT	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FEZ32_12290	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
FEZ32_12295	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FEZ32_12300	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FEZ32_12305	ENOG4105CD3	dihydroorotase
FEZ32_12310	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
FEZ32_12330	ENOG4105CPC	Aldo Keto reductase
FEZ32_12340	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
FEZ32_12355	ENOG4108NKJ	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
FEZ32_12370	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FEZ32_12385	ENOG4105DFA	alanine racemase domain protein
FEZ32_12395	ENOG4107QVM	von Willebrand factor, type A
FEZ32_12405	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FEZ32_12435	ENOG4108QVN	serine threonine protein kinase
FEZ32_12445	ENOG4108R3E	Dna-3-methyladenine glycosylase i
FEZ32_12450	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
FEZ32_12455	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
FEZ32_12460	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FEZ32_12475	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
FEZ32_12485	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FEZ32_12505	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FEZ32_12510	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FEZ32_12545	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
FEZ32_12550	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
FEZ32_12555	ENOG4108IYU	L-aspartate oxidase
FEZ32_12565	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
FEZ32_12570	ENOG4105I3K	Ferric uptake regulator, Fur family
FEZ32_12590	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
FEZ32_12645	ENOG4108KQ5	Integrase catalytic subunit
FEZ32_12665	ENOG4108C33	Resolvase
FEZ32_12710	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
FEZ32_12715	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FEZ32_12725	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FEZ32_12735	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FEZ32_12745	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FEZ32_12755	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FEZ32_12770	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
FEZ32_12795	ENOG4105RHA	ABC transporter, permease
FEZ32_12800	ENOG4108IUX	(ABC) transporter
FEZ32_12805	ENOG4105WH1	Two component transcriptional regulator luxr family
FEZ32_12810	ENOG4105ENE	Histidine kinase
FEZ32_12815	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FEZ32_12825	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FEZ32_12830	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FEZ32_12835	ENOG4108SB3	DoxX Family
FEZ32_12845	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FEZ32_12850	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
FEZ32_12870	ENOG4105ECY	inositol monophosphatase
FEZ32_12895	ENOG4105DRS	transport system, permease
FEZ32_12910	ENOG4105CIG	ABC transporter
FEZ32_12920	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FEZ32_12930	ENOG4107SIQ	Naphthoate synthase
FEZ32_12945	ENOG4105E4F	Isochorismate synthase
FEZ32_12955	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
FEZ32_12960	ENOG4107TCW	O-succinylbenzoate synthase
FEZ32_12965	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FEZ32_12970	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
FEZ32_12980	ENOG4105F8X	type iii restriction
FEZ32_12995	ENOG4105C8T	Leucyl-tRNA synthetase
FEZ32_13010	ENOG4108IUK	alpha amylase, catalytic
FEZ32_13025	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
FEZ32_13030	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FEZ32_13045	ENOG41065RQ	ADP-ribosylation crystallin J1
FEZ32_13080	ENOG4108IMY	Transcriptional regulator
FEZ32_13100	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FEZ32_13110	ENOG4107WAU	Protein tyrosine phosphatase
FEZ32_13140	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FEZ32_13245	ENOG4107TB6	phosphoglycerate mutase
FEZ32_13255	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FEZ32_13260	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FEZ32_13265	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FEZ32_13270	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FEZ32_13280	ENOG4105K46	50S ribosomal protein l27
FEZ32_13285	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FEZ32_13290	ENOG4105C03	ribonuclease
FEZ32_13295	ENOG4105D17	glycoside hydrolase, family 3 domain protein
FEZ32_13300	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FEZ32_13310	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FEZ32_13325	ENOG4105CP7	Triose-phosphate isomerase
FEZ32_13330	ENOG4105BZA	Phosphoglycerate kinase
FEZ32_13335	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FEZ32_13340	ENOG4105CIE	May be required for sporulation (By similarity)
FEZ32_13350	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FEZ32_13355	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FEZ32_13400	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FEZ32_13405	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FEZ32_13410	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
