locus-tag	class	description
C0Z11_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C0Z11_00010	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C0Z11_00015	ENOG4107R34	abc transporter permease protein
C0Z11_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C0Z11_00030	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C0Z11_00035	ENOG4105K7N	UPF0232 protein
C0Z11_00040	ENOG4105EIP	mannose-6-phosphate isomerase
C0Z11_00045	ENOG4105CNT	hydrolase family 2
C0Z11_00055	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C0Z11_00060	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C0Z11_00065	ENOG4108ZED	Transmembrane domain of unknown function (DUF3566)
C0Z11_00070	ENOG4105EMD	TRANSCRIPTIONal
C0Z11_00085	ENOG4105JF0	Phosphoenolpyruvate-dependent sugar phosphotransferase system, eiia 2
C0Z11_00090	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
C0Z11_00100	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C0Z11_00140	ENOG4105CHC	glucokinase (EC 2.7.1.2)
C0Z11_00165	ENOG4105DDV	Transcriptional regulator (LacI family
C0Z11_00170	ENOG4105DJB	Major Facilitator Superfamily
C0Z11_00200	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C0Z11_00220	ENOG4105EBR	Carboxylesterase
C0Z11_00225	ENOG4105CHM	Aminotransferase
C0Z11_00230	ENOG41090U3	tautomerase
C0Z11_00235	ENOG4105YHU	PTS system
C0Z11_00240	ENOG4108EQA	pts system
C0Z11_00245	ENOG4105ETZ	PTS System
C0Z11_00250	ENOG4105F3R	pts system mannose fructose sorbose family iid
C0Z11_00255	ENOG4108KP7	hydrolase
C0Z11_00275	ENOG4105DVE	abc transporter atp-binding protein
C0Z11_00285	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
C0Z11_00290	ENOG4105E5Q	amino acid AbC transporter
C0Z11_00295	ENOG4105CDA	abc transporter atp-binding protein
C0Z11_00300	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C0Z11_00315	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
C0Z11_00320	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
C0Z11_00330	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
C0Z11_00340	ENOG4108V4M	Cobalt abc transporter
C0Z11_00345	ENOG4108JJB	ABC transporter
C0Z11_00350	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
C0Z11_00355	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
C0Z11_00360	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C0Z11_00365	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C0Z11_00375	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
C0Z11_00405	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
C0Z11_00430	ENOG4105I6B	RNA polymerase
C0Z11_00460	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C0Z11_00465	ENOG4105CXT	aspartate transcarbamylase
C0Z11_00470	ENOG4105CTZ	aminopeptidase c
C0Z11_00475	ENOG41064HX	Suppressor of fused protein (SUFU)
C0Z11_00480	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
C0Z11_00485	ENOG4105C9Q	fumarate hydratase class II
C0Z11_00550	ENOG4105C26	Dehydrogenase
C0Z11_00555	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C0Z11_00565	ENOG4105WYW	fructose-bisphosphate aldolase
C0Z11_00575	ENOG4105BZU	Histidine kinase
C0Z11_00585	ENOG4108M15	ABC transporter
C0Z11_00590	ENOG4105CKU	formyltetrahydrofolate synthetase
C0Z11_00615	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C0Z11_00620	ENOG4105WH1	Two component transcriptional regulator luxr family
C0Z11_00625	ENOG4105BZU	Histidine kinase
C0Z11_00635	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
C0Z11_00645	ENOG4105EYF	MMPL domain protein
C0Z11_00655	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C0Z11_00660	ENOG4105C6K	Malic enzyme
C0Z11_00685	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
C0Z11_00695	ENOG4105CD5	CoA-binding domain protein
C0Z11_00710	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C0Z11_00725	ENOG4105CTQ	phosphohexokinase
C0Z11_00735	ENOG4105CEI	nitrite reductase
C0Z11_00755	ENOG4105C0H	protease
C0Z11_00795	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
C0Z11_00805	ENOG41062D9	Histidine kinase
C0Z11_00825	ENOG4105BZ1	(ABC) transporter
C0Z11_00830	ENOG4105BZ1	(ABC) transporter
C0Z11_00835	ENOG4105CG3	alpha amylase, catalytic region
C0Z11_00845	ENOG4105KT7	mgtC SapB transporter
C0Z11_00850	ENOG4105CJQ	hydrolase, family 31
C0Z11_00920	ENOG4105CPP	Dehydrogenase, E1 component
C0Z11_00925	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
C0Z11_00935	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C0Z11_00945	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
C0Z11_00955	ENOG4105CQC	Prephenate dehydratase
C0Z11_00960	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C0Z11_00975	ENOG4108KP7	hydrolase
C0Z11_01000	ENOG4105CB2	alcohol dehydrogenase
C0Z11_01005	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C0Z11_01010	ENOG4105ETE	Transcriptional regulator (LacI family
C0Z11_01015	ENOG4108RCF	TRANSCRIPTIONal
C0Z11_01035	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
C0Z11_01040	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C0Z11_01060	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C0Z11_01070	ENOG4108Z6B	deaminase
C0Z11_01105	ENOG4105FQP	Beta-lactamase
C0Z11_01115	ENOG4105E90	ABC transporter
C0Z11_01125	ENOG4108IJ8	ABC transporter
C0Z11_01130	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
C0Z11_01145	ENOG4105C87	Aminotransferase class I and II
C0Z11_01155	ENOG4105K6T	rare lipoprotein A
C0Z11_01160	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C0Z11_01165	ENOG4105ETE	Transcriptional regulator (LacI family
C0Z11_01170	ENOG4105C2J	ABC transporter
C0Z11_01175	ENOG4105CNN	ABC, transporter
C0Z11_01180	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C0Z11_01185	ENOG4108RVA	ribokinase
C0Z11_01190	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
C0Z11_01195	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C0Z11_01205	ENOG4108SU4	UPF0309 protein
C0Z11_01215	ENOG4105WS7	Cation transport regulator
C0Z11_01225	ENOG4107S2Z	UPF0761 membrane protein
C0Z11_01245	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
C0Z11_01255	ENOG4105DQE	DNA ligase
C0Z11_01280	ENOG4105PWE	CRISPR-associated protein cas2
C0Z11_01285	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
C0Z11_01330	ENOG4106H3A	restriction
C0Z11_01335	ENOG4105DJ2	Major Facilitator Superfamily
C0Z11_01380	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C0Z11_01385	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C0Z11_01390	ENOG4107Z1W	Fructose transport system kinase
C0Z11_01395	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C0Z11_01410	ENOG4105D1Q	UPF0246 protein
C0Z11_01420	ENOG4108JQ7	(ABC) transporter
C0Z11_01425	ENOG4105C3U	ABC transporter
C0Z11_01430	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C0Z11_01460	ENOG4105DIN	metallophosphoesterase
C0Z11_01465	ENOG4105BZ4	penicillin-binding protein
C0Z11_01480	ENOG4105IJJ	transcriptional regulator, crp fnr family
C0Z11_01545	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C0Z11_01550	ENOG4108I5C	dEAD DEAH box helicase
C0Z11_01555	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C0Z11_01565	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C0Z11_01575	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C0Z11_01580	ENOG4105C6E	dna polymerase iii
C0Z11_01590	ENOG4105MA4	psp1 domain protein
C0Z11_01595	ENOG4106JDR	secreted
C0Z11_01640	ENOG4105CPQ	Dehydrogenase
C0Z11_01655	ENOG4108YYH	Nadph-dependent fmn reductase
C0Z11_01685	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C0Z11_01690	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C0Z11_01705	ENOG4105EW9	transcriptional regulator AsnC family
C0Z11_01750	ENOG4105I82	acetyl xylan esterase
C0Z11_01760	ENOG4105F0N	pyrophosphate phospho-hydrolase
C0Z11_01770	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C0Z11_01785	ENOG4105EUJ	GTP cyclohydrolase i
C0Z11_01800	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C0Z11_01820	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C0Z11_01825	ENOG4105DVF	Cytosine-specific methyltransferase
C0Z11_01905	ENOG4108I5D	sulfate abc transporter
C0Z11_01910	ENOG4108UCS	ABC, transporter
C0Z11_01920	ENOG4105C54	Major Facilitator superfamily
C0Z11_01925	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
C0Z11_01930	ENOG4105ETE	Transcriptional regulator (LacI family
C0Z11_01935	ENOG4105CH6	catalase
C0Z11_01945	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C0Z11_01960	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C0Z11_01970	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C0Z11_01975	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C0Z11_01980	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C0Z11_01990	ENOG4105VMP	Transcriptional regulator
C0Z11_02005	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C0Z11_02015	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
C0Z11_02035	ENOG4105II7	pyrroline-5-carboxylate reductase
C0Z11_02050	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C0Z11_02055	ENOG4108RH7	phosphoglycerate mutase
C0Z11_02060	ENOG4107ZT5	Thiol disulfide interchange protein
C0Z11_02065	ENOG4107QIV	Cytochrome c biogenesis protein
C0Z11_02080	ENOG4105CRE	cytochrome C
C0Z11_02090	ENOG4105CHR	reductase
C0Z11_02095	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C0Z11_02105	ENOG4105C7B	Threonine dehydratase
C0Z11_02130	ENOG4105E0A	ABC, transporter
C0Z11_02135	ENOG4108IHU	transport system permease protein
C0Z11_02140	ENOG4105DQ5	transport system permease protein
C0Z11_02145	ENOG4108MES	Periplasmic binding protein
C0Z11_02150	ENOG4105BZ1	(ABC) transporter
C0Z11_02155	ENOG4105BZ1	(ABC) transporter
C0Z11_02160	ENOG41068HZ	50S ribosomal protein L32
C0Z11_02170	ENOG4105W0E	50S ribosomal protein L33
C0Z11_02175	ENOG4105NRA	50s ribosomal protein l31 type b
C0Z11_02180	ENOG4105KDC	50s ribosomal protein l28
C0Z11_02185	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C0Z11_02200	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
C0Z11_02210	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C0Z11_02215	ENOG4107NHD	transcriptional regulator
C0Z11_02235	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C0Z11_02245	ENOG4108SVG	May play a role in the intracellular transport of hydrophobic ligands
C0Z11_02250	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
C0Z11_02275	ENOG4105CI3	gtp-binding protein typa
C0Z11_02280	ENOG4105DXB	Major Facilitator superfamily
C0Z11_02310	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C0Z11_02315	ENOG4105CDU	Replicative dna helicase
C0Z11_02320	ENOG4105VPX	protein, conserved in bacteria
C0Z11_02325	ENOG410681U	heavy metal transport detoxification protein
C0Z11_02335	ENOG4105K6T	rare lipoprotein A
C0Z11_02340	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
C0Z11_02345	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
C0Z11_02350	ENOG4105BZ8	glutamate synthase
C0Z11_02355	ENOG41073TP	transcriptional regulator
C0Z11_02360	ENOG4105DAA	L-lactate
C0Z11_02365	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C0Z11_02370	ENOG4107QR9	Iron-sulfur cluster binding protein
C0Z11_02375	ENOG41080R8	Conserved Protein
C0Z11_02380	ENOG4108JJ8	(ABC) transporter
C0Z11_02385	ENOG4108JJ9	ABC, transporter
C0Z11_02390	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C0Z11_02395	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C0Z11_02430	ENOG4105C0A	alcohol dehydrogenase
C0Z11_02450	ENOG4107VXZ	Hydrolase
C0Z11_02455	ENOG4105C5B	carbamate kinase
C0Z11_02465	ENOG4107REC	cytoplasmic protein
C0Z11_02470	ENOG4107R1Q	Membrane protein FdrA
C0Z11_02495	ENOG4107STF	Involved in phosphonate degradation (By similarity)
C0Z11_02505	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
C0Z11_02520	ENOG4105K8R	UPF0145 protein
C0Z11_02530	ENOG4105ZJT	Cell division protein CrgA
C0Z11_02545	ENOG4105DDQ	anthranilate synthase
C0Z11_02555	ENOG4105CJN	penicillin-binding protein
C0Z11_02570	ENOG4105HZM	Fha domain containing protein
C0Z11_02575	ENOG4105TV9	FHA Domain-Containing protein
C0Z11_02585	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
C0Z11_02590	ENOG4107QPT	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
C0Z11_02630	ENOG4105D3Q	Sugar transferase
C0Z11_02660	ENOG4108KQ5	Integrase catalytic subunit
C0Z11_02730	ENOG4107YJ4	chain length determinant protein
C0Z11_02765	ENOG4105CSH	Transporter
C0Z11_02825	ENOG41087ID	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C0Z11_02830	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C0Z11_02850	ENOG410667J	hydrolase
C0Z11_02855	ENOG4105DQF	Hydrolase
C0Z11_02860	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C0Z11_02880	ENOG4105CFH	Aspartokinase
C0Z11_02890	ENOG4108ZJ4	polysaccharide deacetylase
C0Z11_02900	ENOG4105D94	Major Facilitator Superfamily
C0Z11_02915	ENOG4107R5R	arsenical pump membrane protein
C0Z11_02920	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C0Z11_02930	ENOG41085J0	Protein CrcB homolog
C0Z11_02935	ENOG41083TI	Protein CrcB homolog
C0Z11_02940	ENOG4105CPC	Aldo Keto reductase
C0Z11_02965	ENOG4105CQR	helicase
C0Z11_02980	ENOG4107QP8	phosphohexose isomerase
C0Z11_02995	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C0Z11_03000	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C0Z11_03005	ENOG4107RRN	ABC transporter substrate-binding protein
C0Z11_03010	ENOG4108UB4	uncharacterized protein ygjQ
C0Z11_03015	ENOG4105IE8	Alpha-ketoglutarate permease
C0Z11_03020	ENOG4105CV8	reductase
C0Z11_03025	ENOG4105C75	arginyL-tRNA synthetase
C0Z11_03035	ENOG4105CKV	Membrane
C0Z11_03045	ENOG4105J4Q	Transcriptional regulator
C0Z11_03055	ENOG4105DH8	myo-inositol catabolism
C0Z11_03060	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C0Z11_03065	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
C0Z11_03070	ENOG4107QNK	)-transporter
C0Z11_03080	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C0Z11_03085	ENOG4105C6K	Malic enzyme
C0Z11_03100	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C0Z11_03130	ENOG4105FDP	GntR family transcriptional regulator
C0Z11_03140	ENOG4105ETE	Transcriptional regulator (LacI family
C0Z11_03160	ENOG4108JQ7	(ABC) transporter
C0Z11_03195	ENOG4105DSB	aldose 1-epimerase
C0Z11_03200	ENOG4105EAC	phosphoserine phosphatase
C0Z11_03205	ENOG4107RNR	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA (By similarity)
C0Z11_03210	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
C0Z11_03215	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
C0Z11_03230	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C0Z11_03240	ENOG4105EDW	glycosyl transferase, family 39
C0Z11_03255	ENOG4105BZU	Histidine kinase
C0Z11_03260	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C0Z11_03280	ENOG4105CFG	Acts as a chaperone (By similarity)
C0Z11_03285	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C0Z11_03290	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C0Z11_03295	ENOG4105KNI	merR family transcriptional Regulator
C0Z11_03305	ENOG4107FQX	Alpha-acetolactate decarboxylase
C0Z11_03310	ENOG4107WGA	YidE YbjL
C0Z11_03315	ENOG4105C85	amino acid
C0Z11_03320	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C0Z11_03325	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C0Z11_03335	ENOG4105WH1	Two component transcriptional regulator luxr family
C0Z11_03340	ENOG4105BZU	Histidine kinase
C0Z11_03350	ENOG4105WYW	fructose-bisphosphate aldolase
C0Z11_03365	ENOG4105DRS	transport system, permease
C0Z11_03375	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C0Z11_03390	ENOG4105DFH	Transport of potassium into the cell (By similarity)
C0Z11_03405	ENOG4105K5B	UPF0225 protein
C0Z11_03410	ENOG4105CVK	Glutamate decarboxylase
C0Z11_03415	ENOG4105DZR	Type I site-specific deoxyribonuclease
C0Z11_03425	ENOG4105CVR	type I restriction-modification system
C0Z11_03440	ENOG4105K5B	UPF0225 protein
C0Z11_03445	ENOG4108IJ7	Glycine betaine
C0Z11_03450	ENOG4108HQS	Glycine betaine
C0Z11_03475	ENOG4108V0P	LemA family
C0Z11_03480	ENOG4105DQR	SNARE associated Golgi
C0Z11_03495	ENOG4107RCW	fructose-bisphosphate aldolase
C0Z11_03500	ENOG4105NX3	Membrane
C0Z11_03505	ENOG4107QSA	Oxaloacetate decarboxylase
C0Z11_03510	ENOG4107QX3	carboxylase
C0Z11_03515	ENOG4107QX3	carboxylase
C0Z11_03520	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
C0Z11_03530	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C0Z11_03535	ENOG410849S	phosphocarrier protein (HPr)
C0Z11_03540	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C0Z11_03545	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C0Z11_03550	ENOG4105BZU	Histidine kinase
C0Z11_03565	ENOG4108VJ1	Transcriptional regulator (CarD family
C0Z11_03580	ENOG4105DT3	PTS system, galactitol-specific IIc component
C0Z11_03590	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C0Z11_03595	ENOG4105DKT	Transcriptional regulator
C0Z11_03605	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C0Z11_03610	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C0Z11_03615	ENOG4105DTQ	mandelate racemase muconate lactonizing
C0Z11_03630	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C0Z11_03645	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C0Z11_03650	ENOG4105EQ0	Major Facilitator superfamily
C0Z11_03660	ENOG4105C8N	cysteinyl-tRNA synthetase
C0Z11_03675	ENOG4105C28	cystathionine
C0Z11_03685	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C0Z11_03695	ENOG4105EJQ	L-serine dehydratase
C0Z11_03700	ENOG4105CPQ	Dehydrogenase
C0Z11_03705	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C0Z11_03710	ENOG4105K78	MarR family Transcriptional regulator
C0Z11_03720	ENOG4108UVJ	appr-1-p processing domain protein
C0Z11_03745	ENOG4105ENE	Histidine kinase
C0Z11_03750	ENOG4105WH1	Two component transcriptional regulator luxr family
C0Z11_03755	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
C0Z11_03760	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C0Z11_03775	ENOG4105E4R	Precorrin-3B C17-methyltransferase
C0Z11_03780	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C0Z11_03795	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
C0Z11_03800	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C0Z11_03805	ENOG4105F0H	myo-inositol catabolism protein
C0Z11_03810	ENOG4105ETE	Transcriptional regulator (LacI family
C0Z11_03815	ENOG4107QNK	)-transporter
C0Z11_03845	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
C0Z11_03850	ENOG4105C4B	ABC transporter, permease
C0Z11_03855	ENOG4105VEQ	Cold shock protein
C0Z11_03870	ENOG4105C7N	Xanthine uracil vitamin C permease
C0Z11_03885	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C0Z11_03890	ENOG4105CE4	GlcNAc 6-P deacetylase
C0Z11_03895	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
C0Z11_03900	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C0Z11_03905	ENOG4105K63	Thioredoxin
C0Z11_03910	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C0Z11_03915	ENOG4105D7K	pfkb domain protein
C0Z11_03925	ENOG4105DH8	myo-inositol catabolism
C0Z11_03930	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
C0Z11_03940	ENOG4105ETE	Transcriptional regulator (LacI family
C0Z11_03950	ENOG4107QNK	)-transporter
C0Z11_04010	ENOG4105C02	permease
C0Z11_04025	ENOG41082SX	arsR family transcriptional regulator
C0Z11_04035	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C0Z11_04040	ENOG4105D9R	oxidoreductase
C0Z11_04070	ENOG4108Z6Z	Transcriptional regulator
C0Z11_04085	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C0Z11_04115	ENOG4105E7W	lamb ycsf family protein
C0Z11_04120	ENOG4107R7A	Allophanate hydrolase subunit 2
C0Z11_04125	ENOG4107TPY	serine threonine protein kinase
C0Z11_04130	ENOG4105C2W	permease
C0Z11_04145	ENOG4105F8V	Hydrolase, tatD family
C0Z11_04150	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C0Z11_04155	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C0Z11_04160	ENOG41062A4	Transcriptional regulator
C0Z11_04175	ENOG4107U1N	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C0Z11_04180	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C0Z11_04185	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C0Z11_04190	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C0Z11_04210	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C0Z11_04255	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C0Z11_04285	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C0Z11_04290	ENOG41084BS	50S ribosomal protein L35
C0Z11_04295	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C0Z11_04310	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C0Z11_04315	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C0Z11_04320	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
C0Z11_04330	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
C0Z11_04335	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C0Z11_04375	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C0Z11_04380	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C0Z11_04395	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C0Z11_04410	ENOG4105C7Z	Conserved Protein
C0Z11_04415	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C0Z11_04435	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C0Z11_04440	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C0Z11_04445	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C0Z11_04455	ENOG4105DFM	M18 family aminopeptidase
C0Z11_04465	ENOG4105C3G	gtp-binding protein
C0Z11_04500	ENOG41084HI	prevent-host-death family
C0Z11_04510	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
C0Z11_04525	ENOG4105BZ1	(ABC) transporter
C0Z11_04540	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C0Z11_04545	ENOG4108RWI	nicotinamidase
C0Z11_04565	ENOG4105CSH	Transporter
C0Z11_04605	ENOG4105CPC	Aldo Keto reductase
C0Z11_04625	ENOG4105CMN	Methylmalonyl-coA mutase
C0Z11_04630	ENOG4105D5P	Methylmalonyl-coA mutase
C0Z11_04640	ENOG410848D	S4 domain protein YaaA
C0Z11_04650	ENOG4105E5Q	amino acid AbC transporter
C0Z11_04655	ENOG4106PMH	Extracellular solute-binding protein family 3
C0Z11_04675	ENOG4105CC5	ABC transporter
C0Z11_04680	ENOG4105DIK	(ABC) transporter
C0Z11_04710	ENOG4108IUW	ABC transporter
C0Z11_04725	ENOG4105C26	Dehydrogenase
C0Z11_04730	ENOG4105CPQ	Dehydrogenase
C0Z11_04735	ENOG4105CMT	Dihydroxyacetone kinase
C0Z11_04745	ENOG4105E98	transcriptional regulator DeoR family
C0Z11_04750	ENOG4107YVI	ribose 5-phosphate isomerase
C0Z11_04760	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
C0Z11_04770	ENOG4108MDK	Dehydrogenase
C0Z11_04775	ENOG4105EF1	ribulokinase
C0Z11_04800	ENOG4107Y80	Major Facilitator superfamily
C0Z11_04805	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C0Z11_04810	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C0Z11_04815	ENOG4107S1E	Beta-lactamase
C0Z11_04825	ENOG4108Z4U	Ferredoxin
C0Z11_04845	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
C0Z11_04850	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
C0Z11_04855	ENOG4108URH	decarboxylase
C0Z11_04870	ENOG4107QPH	glycogen) synthase
C0Z11_04875	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C0Z11_04890	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C0Z11_04895	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C0Z11_04925	ENOG4107T6F	Xaa-Pro aminopeptidase
C0Z11_04935	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
C0Z11_04940	ENOG4105CUB	amino acid
C0Z11_04960	ENOG4105D7N	magnesium and cobalt transport protein CorA
C0Z11_04975	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C0Z11_04980	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C0Z11_05035	ENOG4105C5F	glutamine synthetase
C0Z11_05045	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C0Z11_05050	ENOG4105DWK	Membrane
C0Z11_05055	ENOG4105EGD	dinuclear metal center protein, YbgI family
C0Z11_05060	ENOG4105C5F	glutamine synthetase
C0Z11_05075	ENOG4105E2K	Glycosyl transferase (Group 1
C0Z11_05085	ENOG4105C5H	ABC transporter
C0Z11_05095	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C0Z11_05110	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C0Z11_05155	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
C0Z11_05160	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C0Z11_05165	ENOG4105MCD	Part of cytochrome c oxidase, its function is
C0Z11_05185	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C0Z11_05190	ENOG4107EUI	c reductase, iron-sulfur
C0Z11_05195	ENOG4107UDY	cytochrome C
C0Z11_05200	ENOG4105CCU	oxidase (Subunit III)
C0Z11_05210	ENOG4107S1N	anthranilate phosphoribosyltransferase
C0Z11_05250	ENOG4105ZXU	NLP P60 protein
C0Z11_05255	ENOG4105DKQ	ROK family
C0Z11_05280	ENOG4105WH1	Two component transcriptional regulator luxr family
C0Z11_05285	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
C0Z11_05310	ENOG4105EAH	synthase
C0Z11_05325	ENOG4105C4R	Atp-dependent dna helicase
C0Z11_05345	ENOG4105E2Y	ABC, transporter
C0Z11_05360	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
C0Z11_05370	ENOG4105CJ1	ABC, transporter
C0Z11_05380	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0Z11_05385	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C0Z11_05390	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C0Z11_05405	ENOG4105F8C	transglutaminase domain-containing protein
C0Z11_05415	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C0Z11_05420	ENOG4108V6E	Cell division protein mraZ
C0Z11_05425	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C0Z11_05435	ENOG4105CJN	penicillin-binding protein
C0Z11_05450	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C0Z11_05455	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C0Z11_05465	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C0Z11_05470	ENOG4105DFU	Cell wall formation (By similarity)
C0Z11_05480	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C0Z11_05485	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C0Z11_05490	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
C0Z11_05505	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0Z11_05510	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C0Z11_05520	ENOG4105CA9	Pyruvate kinase
C0Z11_05535	ENOG4105KA0	thioesterase Superfamily protein
C0Z11_05550	ENOG410829K	Lysine exporter protein (Lyse ygga)
C0Z11_05570	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C0Z11_05575	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C0Z11_05580	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C0Z11_05620	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C0Z11_05625	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C0Z11_05635	ENOG4105CIE	May be required for sporulation (By similarity)
C0Z11_05640	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C0Z11_05645	ENOG4105BZA	Phosphoglycerate kinase
C0Z11_05650	ENOG4105CP7	Triose-phosphate isomerase
C0Z11_05665	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C0Z11_05675	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C0Z11_05680	ENOG4105D17	glycoside hydrolase, family 3 domain protein
C0Z11_05685	ENOG4105C03	ribonuclease
C0Z11_05690	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C0Z11_05695	ENOG4105K46	50S ribosomal protein l27
C0Z11_05705	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C0Z11_05710	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C0Z11_05715	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C0Z11_05720	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C0Z11_05730	ENOG4107TB6	phosphoglycerate mutase
C0Z11_05775	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C0Z11_05810	ENOG41065RQ	ADP-ribosylation crystallin J1
C0Z11_05845	ENOG4108IUK	alpha amylase, catalytic
C0Z11_05860	ENOG4105C8T	Leucyl-tRNA synthetase
C0Z11_05875	ENOG4105F8X	type iii restriction
C0Z11_05885	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C0Z11_05890	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C0Z11_05895	ENOG4107TCW	O-succinylbenzoate synthase
C0Z11_05900	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C0Z11_05910	ENOG4105E4F	Isochorismate synthase
C0Z11_05925	ENOG4107SIQ	Naphthoate synthase
C0Z11_05935	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C0Z11_05940	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C0Z11_05950	ENOG4105CIG	ABC transporter
C0Z11_05965	ENOG4105DRS	transport system, permease
C0Z11_05990	ENOG4105ECY	inositol monophosphatase
C0Z11_05995	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C0Z11_06000	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C0Z11_06005	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C0Z11_06015	ENOG4108SB3	DoxX Family
C0Z11_06020	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C0Z11_06025	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C0Z11_06035	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C0Z11_06040	ENOG4105BZU	Histidine kinase
C0Z11_06045	ENOG4105WH1	Two component transcriptional regulator luxr family
C0Z11_06050	ENOG4108IUX	(ABC) transporter
C0Z11_06055	ENOG4105RHA	ABC transporter, permease
C0Z11_06080	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
C0Z11_06095	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C0Z11_06105	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C0Z11_06115	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C0Z11_06120	ENOG4105CT1	(ABC) transporter
C0Z11_06125	ENOG4105E5Q	amino acid AbC transporter
C0Z11_06130	ENOG4105EAD	ABC transporter
C0Z11_06140	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C0Z11_06150	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C0Z11_06155	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
C0Z11_06185	ENOG4108KQ5	Integrase catalytic subunit
C0Z11_06245	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C0Z11_06270	ENOG4105I3K	Ferric uptake regulator, Fur family
C0Z11_06275	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
C0Z11_06285	ENOG4108IYU	L-aspartate oxidase
C0Z11_06290	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
C0Z11_06295	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
C0Z11_06300	ENOG4105CVK	Glutamate decarboxylase
C0Z11_06330	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
C0Z11_06335	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C0Z11_06355	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C0Z11_06360	ENOG4105C5H	ABC transporter
C0Z11_06365	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
C0Z11_06380	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C0Z11_06385	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
C0Z11_06390	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
C0Z11_06400	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
C0Z11_06405	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C0Z11_06410	ENOG4108QVN	serine threonine protein kinase
C0Z11_06415	ENOG4108UGD	Serine Threonine protein kinase
C0Z11_06450	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C0Z11_06460	ENOG4107QVM	von Willebrand factor, type A
C0Z11_06470	ENOG4105DFA	alanine racemase domain protein
C0Z11_06485	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C0Z11_06500	ENOG4108NKJ	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C0Z11_06515	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C0Z11_06525	ENOG4105CPC	Aldo Keto reductase
C0Z11_06540	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C0Z11_06545	ENOG4105CD3	dihydroorotase
C0Z11_06550	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C0Z11_06555	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C0Z11_06560	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
C0Z11_06565	ENOG4107TYT	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
C0Z11_06570	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
C0Z11_06575	ENOG4107T52	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C0Z11_06585	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
C0Z11_06595	ENOG4105CEV	competence damage-inducible protein
C0Z11_06605	ENOG4105E98	transcriptional regulator DeoR family
C0Z11_06615	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C0Z11_06620	ENOG4105KC9	Modulates RecA activity (By similarity)
C0Z11_06625	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
C0Z11_06630	ENOG4107WI4	Aldose-1-epimerase
C0Z11_06635	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C0Z11_06645	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C0Z11_06650	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C0Z11_06655	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C0Z11_06670	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C0Z11_06675	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C0Z11_06680	ENOG4105DHP	deoxycytidine triphosphate deaminase
C0Z11_06705	ENOG4105CQ7	ATP-dependent helicase
C0Z11_06710	ENOG4105CT8	Phosphorylase
C0Z11_06715	ENOG4105C29	acyl-CoA thioesterase
C0Z11_06725	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C0Z11_06730	ENOG4105E2D	ec 3.2.1.52
C0Z11_06745	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C0Z11_06765	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C0Z11_06800	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C0Z11_06825	ENOG4107VEG	TrkA-N domain protein
C0Z11_06830	ENOG4105C0X	amino acid
C0Z11_06835	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C0Z11_06880	ENOG4108JJB	ABC transporter
C0Z11_06885	ENOG4108JQ7	(ABC) transporter
C0Z11_06890	ENOG4107QM5	aconitate hydratase
C0Z11_06895	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C0Z11_06910	ENOG4105E0X	reductase
C0Z11_06940	ENOG4108HKT	sucrose-6-phosphate hydrolase
C0Z11_06945	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
C0Z11_06955	ENOG4107UVD	Beta-phosphoglucomutase family hydrolase
C0Z11_06970	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C0Z11_06975	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
C0Z11_06990	ENOG4108KQ5	Integrase catalytic subunit
C0Z11_07000	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C0Z11_07015	ENOG4105E2Y	ABC, transporter
C0Z11_07040	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C0Z11_07045	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C0Z11_07050	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C0Z11_07055	ENOG4105C2W	permease
C0Z11_07070	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C0Z11_07075	ENOG4105CRQ	synthase (Component I)
C0Z11_07090	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C0Z11_07095	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C0Z11_07100	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C0Z11_07105	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C0Z11_07110	ENOG4105CBC	glutamate synthase
C0Z11_07145	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C0Z11_07150	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C0Z11_07155	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C0Z11_07160	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C0Z11_07165	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C0Z11_07170	ENOG4105CDY	transcriptional regulatory protein
C0Z11_07175	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C0Z11_07180	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C0Z11_07185	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C0Z11_07195	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C0Z11_07200	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C0Z11_07205	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C0Z11_07215	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C0Z11_07220	ENOG4105D98	threonine synthase
C0Z11_07225	ENOG4105C99	atpase involved in dna repair
C0Z11_07235	ENOG4105CUT	histidyl-tRNA synthetase
C0Z11_07250	ENOG4105PGM	cation diffusion facilitator family transporter
C0Z11_07255	ENOG4105CIZ	coA-substrate-specific enzyme activase
C0Z11_07260	ENOG4107MVR	Transcriptional regulator
C0Z11_07270	ENOG4105C9M	aspartyl-trna synthetase
C0Z11_07300	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C0Z11_07305	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C0Z11_07315	ENOG4105E2X	shikimate dehydrogenase
C0Z11_07320	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C0Z11_07330	ENOG4105D49	3-dehydroquinate synthase
C0Z11_07340	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C0Z11_07345	ENOG410803B	Involved in the transcription termination process (By similarity)
C0Z11_07355	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C0Z11_07360	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C0Z11_07370	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C0Z11_07375	ENOG4107QRT	dEAD DEAH box helicase
C0Z11_07380	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
C0Z11_07395	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C0Z11_07405	ENOG4105DJV	ribulose-phosphate 3-epimerase
C0Z11_07415	ENOG4105C3R	Methionine synthase
C0Z11_07430	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
C0Z11_07435	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
C0Z11_07445	ENOG4105CAT	Cytidine monophosphate kinase
C0Z11_07460	ENOG4108Z9K	Osmotically inducible protein
C0Z11_07495	ENOG4107QUV	Domain protein
C0Z11_07510	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
C0Z11_07515	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
C0Z11_07555	ENOG4105C7K	acetolactate synthase
C0Z11_07570	ENOG4105C8Y	Acetylornithine aminotransferase
C0Z11_07585	ENOG4105BZU	Histidine kinase
C0Z11_07670	ENOG410667J	hydrolase
C0Z11_07680	ENOG4105CYC	Transferase
C0Z11_07685	ENOG4105DWV	Homoserine O-trans-acetylase
C0Z11_07690	ENOG4105DWV	Homoserine O-trans-acetylase
C0Z11_07700	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
C0Z11_07705	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
C0Z11_07710	ENOG4105Q70	
C0Z11_07715	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
C0Z11_07720	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
C0Z11_07725	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C0Z11_07740	ENOG4105CUB	amino acid
C0Z11_07770	ENOG4105CFG	Acts as a chaperone (By similarity)
C0Z11_07785	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C0Z11_07790	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
C0Z11_07795	ENOG4107TE5	Lipid kinase
C0Z11_07800	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C0Z11_07805	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
C0Z11_07815	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
C0Z11_07820	ENOG4107H3J	ribonuclease
C0Z11_07840	ENOG4108UW8	fha domain-containing protein
C0Z11_07845	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C0Z11_07865	ENOG4105E2K	Glycosyl transferase (Group 1
C0Z11_07870	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
C0Z11_07875	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
C0Z11_07885	ENOG4105C22	threonyL-tRNA synthetase
C0Z11_07920	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
C0Z11_07930	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C0Z11_07945	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C0Z11_07950	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C0Z11_07955	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C0Z11_07960	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C0Z11_07965	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C0Z11_07970	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
C0Z11_07975	ENOG4105ZA1	atp synthase
C0Z11_07980	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
C0Z11_08000	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C0Z11_08005	ENOG4105CAQ	asparagine synthetase
C0Z11_08015	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C0Z11_08025	ENOG4105CEY	Amp-dependent synthetase and ligase
C0Z11_08100	ENOG4105ESV	Glycosyl transferase, family 4
C0Z11_08110	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C0Z11_08115	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C0Z11_08120	ENOG4105VFB	Binds the 23S rRNA (By similarity)
C0Z11_08130	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C0Z11_08135	ENOG4105D6E	homoserine dehydrogenase
C0Z11_08140	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C0Z11_08150	ENOG4108URH	decarboxylase
C0Z11_08160	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C0Z11_08185	ENOG4105EMN	RNA polymerase sigma factor
C0Z11_08195	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C0Z11_08210	ENOG4107TK4	histidinol-phosphate phosphatase
C0Z11_08215	ENOG4108JQ1	Dehydrogenase
C0Z11_08220	ENOG4108JQ7	(ABC) transporter
C0Z11_08230	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C0Z11_08260	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
C0Z11_08265	ENOG4105DJZ	UPF0182 protein
C0Z11_08275	ENOG41063PX	domain protein
C0Z11_08300	ENOG4107QKA	exodeoxyribonuclease V beta
C0Z11_08325	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
C0Z11_08330	ENOG4105VEQ	Cold shock protein
C0Z11_08360	ENOG4105C31	Tryptophanyl-tRNA synthetase
C0Z11_08370	ENOG4105C7I	Dehydrogenase
C0Z11_08390	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C0Z11_08400	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
C0Z11_08410	ENOG4105G3P	Lipoprotein lpqB
C0Z11_08415	ENOG4105BZU	Histidine kinase
C0Z11_08420	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C0Z11_08425	ENOG4108UJU	UPF0301 protein
C0Z11_08430	ENOG4108Z7F	N-acetyltransferase
C0Z11_08515	ENOG4105CH7	arginosuccinase
C0Z11_08525	ENOG4105C8Y	Acetylornithine aminotransferase
C0Z11_08530	ENOG4105CAS	nag kinase
C0Z11_08535	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C0Z11_08540	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C0Z11_08545	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C0Z11_08555	ENOG4105CAK	Cell division ATP-binding protein ftsE
C0Z11_08560	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
C0Z11_08580	ENOG4107QZI	cell division protein FtsK
C0Z11_08600	ENOG4105CPF	Cell wall formation (By similarity)
C0Z11_08610	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C0Z11_08615	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C0Z11_08620	ENOG41069M3	Transcriptional regulator
C0Z11_08635	ENOG4107FCW	Abortive infection protein
C0Z11_08640	ENOG4105ERH	Fumarylacetoacetate hydrolase
C0Z11_08650	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C0Z11_08655	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C0Z11_08660	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C0Z11_08670	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C0Z11_08685	ENOG4105K59	histidine triad (HIT) protein
C0Z11_08690	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C0Z11_08695	ENOG4105CQR	helicase
C0Z11_08720	ENOG4107TMB	Transcriptional regulator
C0Z11_08730	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
C0Z11_08735	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C0Z11_08755	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C0Z11_08760	ENOG4108YZ4	nudix hydrolase
C0Z11_08765	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C0Z11_08770	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C0Z11_08775	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C0Z11_08785	ENOG4108JJB	ABC transporter
C0Z11_08790	ENOG4105VKD	bioY protein
C0Z11_08795	ENOG4105DSU	hydrolase
C0Z11_08830	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C0Z11_08835	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
C0Z11_08850	ENOG4105CPC	Aldo Keto reductase
C0Z11_08860	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C0Z11_08910	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C0Z11_08915	ENOG4105XTG	Pfam:DUF156
C0Z11_08920	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C0Z11_08930	ENOG4105BZU	Histidine kinase
C0Z11_08935	ENOG4105ETX	regulatoR
C0Z11_08940	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C0Z11_08945	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
C0Z11_08950	ENOG4105C4B	ABC transporter, permease
C0Z11_08965	ENOG4105CMQ	Chloride channel
C0Z11_09045	ENOG4105C0P	Mg chelatase subunit ChlI
C0Z11_09050	ENOG41080R2	UPF0102 protein
C0Z11_09060	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C0Z11_09065	ENOG4107QYR	Signal peptidase i
C0Z11_09070	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C0Z11_09080	ENOG4105E33	succinate dehydrogenase
C0Z11_09095	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C0Z11_09100	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C0Z11_09105	ENOG41082KU	UPF0109 protein
C0Z11_09110	ENOG4105K5M	30s ribosomal protein S16
C0Z11_09140	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
C0Z11_09145	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
C0Z11_09165	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C0Z11_09170	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C0Z11_09185	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C0Z11_09190	ENOG4106H78	methyltransferase
C0Z11_09200	ENOG4105CB5	ATP-dependent DNA helicase recG
C0Z11_09205	ENOG4105VB9	50S ribosomal protein l28
C0Z11_09210	ENOG4105CN5	Metallo-Beta-Lactamase
C0Z11_09220	ENOG4105C7K	acetolactate synthase
C0Z11_09230	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C0Z11_09250	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C0Z11_09270	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C0Z11_09280	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C0Z11_09285	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C0Z11_09290	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C0Z11_09305	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
C0Z11_09320	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C0Z11_09345	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C0Z11_09350	ENOG4105DZP	Membrane-associated zinc metalloprotease
C0Z11_09360	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C0Z11_09365	ENOG4105KNE	Phosphatidate cytidylyltransferase
C0Z11_09370	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C0Z11_09375	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C0Z11_09380	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C0Z11_09385	ENOG4105CE9	30S ribosomal protein S2
C0Z11_09395	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C0Z11_09405	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C0Z11_09415	ENOG4105DHU	Bile acid
C0Z11_09430	ENOG4105DKW	ABC transporter
C0Z11_09435	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C0Z11_09445	ENOG4108IJ0	Aspartate ammonia-lyase
C0Z11_09455	ENOG4105CHR	reductase
C0Z11_09480	ENOG4105C5H	ABC transporter
C0Z11_09505	ENOG4108UNV	SUF system FeS assembly protein, NifU family
C0Z11_09510	ENOG4105C9B	Cysteine desulfurase
C0Z11_09515	ENOG4105C3K	feS assembly ATPase SufC
C0Z11_09530	ENOG4105DIW	FeS assembly protein SUFB
C0Z11_09545	ENOG4105D56	permease protein
C0Z11_09550	ENOG4105EG2	ABC transporter, permease
C0Z11_09555	ENOG4105ETE	Transcriptional regulator (LacI family
C0Z11_09560	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C0Z11_09575	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
C0Z11_09585	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C0Z11_09600	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
C0Z11_09610	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C0Z11_09630	ENOG4107RE3	peptidase, S41
C0Z11_09635	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C0Z11_09640	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C0Z11_09645	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C0Z11_09650	ENOG4105DSF	transport protein
C0Z11_09655	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C0Z11_09675	ENOG4105CRK	lysyL-tRNA synthetase
C0Z11_09695	ENOG4108YZG	isomerase
C0Z11_09710	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C0Z11_09715	ENOG4105MC2	DSBA oxidoreductase
C0Z11_09730	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
C0Z11_09750	ENOG4108IQE	Amp-dependent synthetase and ligase
C0Z11_09765	ENOG4105CQB	FAD linked oxidase domain protein
C0Z11_09795	ENOG4105D5Q	Arginine ornithine antiporter
C0Z11_09800	ENOG4105CEU	Arginine dihydrolase
C0Z11_09805	ENOG4105DFD	Na H antiporter
C0Z11_09835	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C0Z11_09880	ENOG4105CB5	ATP-dependent DNA helicase recG
C0Z11_09900	ENOG4105CF1	Alkylated DNA repair protein
C0Z11_09915	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C0Z11_09965	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
C0Z11_10015	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
C0Z11_10025	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
C0Z11_10030	ENOG4107RPQ	ABC transporter
C0Z11_10035	ENOG4105C85	amino acid
C0Z11_10050	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C0Z11_10055	ENOG4105CUB	amino acid
C0Z11_10115	ENOG4105C0B	DNA polymerase III (alpha subunit)
C0Z11_10130	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C0Z11_10165	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C0Z11_10185	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C0Z11_10190	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
C0Z11_10195	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C0Z11_10200	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C0Z11_10205	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
C0Z11_10210	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C0Z11_10220	ENOG4105CE1	Ferrous iron transport protein b
C0Z11_10235	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C0Z11_10265	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C0Z11_10270	ENOG41076HS	cation diffusion facilitator family transporter
C0Z11_10305	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
C0Z11_10330	ENOG4108KGH	TRANSCRIPTIONal
C0Z11_10350	ENOG4105EC3	peptidase S51, dipeptidase E
C0Z11_10355	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C0Z11_10360	ENOG4105D8K	carboxyl transferase
C0Z11_10370	ENOG4107WR6	Maf-like protein
C0Z11_10385	ENOG4105CEU	Arginine dihydrolase
C0Z11_10390	ENOG4105EMU	Dehydrogenase
C0Z11_10395	ENOG4105DWF	phosphomethylpyrimidine kinase
C0Z11_10410	ENOG4108JIK	carboxylase
C0Z11_10425	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
C0Z11_10430	ENOG4105CEY	Amp-dependent synthetase and ligase
C0Z11_10445	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C0Z11_10465	ENOG4105UIB	(ABC) transporter
C0Z11_10470	ENOG4108JQ9	ABC transporter
C0Z11_10475	ENOG4107TFB	basic membrane
C0Z11_10500	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C0Z11_10510	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C0Z11_10525	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C0Z11_10535	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C0Z11_10540	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C0Z11_10570	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C0Z11_10585	ENOG4105D01	(LipO)protein
C0Z11_10590	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C0Z11_10595	ENOG4108UMI	ABC transporter, permease
C0Z11_10600	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C0Z11_10605	ENOG4105Y3U	Transglycosylase-associated protein
C0Z11_10610	ENOG4105WH1	Two component transcriptional regulator luxr family
C0Z11_10635	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C0Z11_10640	ENOG4105D7W	serine acetyltransferase
C0Z11_10645	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
C0Z11_10650	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C0Z11_10665	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C0Z11_10670	ENOG41072RD	Membrane
C0Z11_10675	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C0Z11_10680	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C0Z11_10725	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C0Z11_10730	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
C0Z11_10740	ENOG4108097	ATP-binding protein
C0Z11_10745	ENOG4105C1J	atp-dependent rna helicase
C0Z11_10765	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
C0Z11_10770	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
C0Z11_10780	ENOG4105E2R	ROK family
C0Z11_10785	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C0Z11_10790	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C0Z11_10795	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C0Z11_10800	ENOG4105CS9	pantothenic acid kinase
C0Z11_10810	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C0Z11_10815	ENOG4108UJD	30S ribosomal protein S9
C0Z11_10820	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C0Z11_10825	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C0Z11_10830	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C0Z11_10835	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C0Z11_10850	ENOG4108JJB	ABC transporter
C0Z11_10860	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C0Z11_10875	ENOG4108MJN	Glycosyl Transferase
C0Z11_10880	ENOG4108ZT0	50S ribosomal protein l17
C0Z11_10885	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C0Z11_10890	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C0Z11_10895	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C0Z11_10900	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C0Z11_10910	ENOG41067V7	50S ribosomal protein L36
C0Z11_10915	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C0Z11_10935	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C0Z11_10970	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C0Z11_10975	ENOG410849U	50S ribosomal protein L30
C0Z11_10980	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C0Z11_10985	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C0Z11_10990	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C0Z11_10995	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C0Z11_11000	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C0Z11_11005	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C0Z11_11010	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C0Z11_11015	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C0Z11_11045	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C0Z11_11050	ENOG41082SA	50s ribosomal protein l29
C0Z11_11055	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C0Z11_11060	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C0Z11_11065	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C0Z11_11070	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C0Z11_11075	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C0Z11_11080	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C0Z11_11085	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C0Z11_11090	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C0Z11_11095	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C0Z11_11100	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C0Z11_11105	ENOG4105CX6	glutaminyL-tRNA synthetase
C0Z11_11110	ENOG4105CGH	5'-nucleotidase
C0Z11_11125	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C0Z11_11130	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C0Z11_11135	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C0Z11_11140	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C0Z11_11145	ENOG4105EE0	oxidoreductase
C0Z11_11155	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C0Z11_11160	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C0Z11_11165	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C0Z11_11170	ENOG4108VZM	50s ribosomal protein L10
C0Z11_11175	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C0Z11_11180	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C0Z11_11185	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C0Z11_11200	ENOG4105XT2	Transcriptional regulator
C0Z11_11205	ENOG4107R4N	Cell wall formation (By similarity)
C0Z11_11215	ENOG410900P	UPF0336 protein
C0Z11_11220	ENOG4105WDJ	50S ribosomal protein L33
C0Z11_11250	ENOG4105CGK	Exodeoxyribonuclease III
C0Z11_11255	ENOG4105CGU	Enoyl-CoA hydratase
C0Z11_11265	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
C0Z11_11270	ENOG4105DQU	oxidoreductase, subunit beta
C0Z11_11280	ENOG4105C9K	Endothelin-converting enzyme 1
C0Z11_11285	ENOG4105CI0	Citrate lyase
C0Z11_11290	ENOG4107FQ9	ethanolamine ammonia-lyase
C0Z11_11295	ENOG4105CPD	ethanolamine ammonia-lyase
C0Z11_11305	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C0Z11_11320	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C0Z11_11325	ENOG4105DF2	NADH dehydrogenase subunit j
C0Z11_11330	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C0Z11_11335	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
C0Z11_11340	ENOG4108IEH	NADH dehydrogenase subunit g
C0Z11_11345	ENOG4107QIZ	NADH dehydrogenase
C0Z11_11355	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C0Z11_11360	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C0Z11_11365	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C0Z11_11380	ENOG4105E4F	Isochorismate synthase
C0Z11_11400	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C0Z11_11410	ENOG4105BZ1	(ABC) transporter
C0Z11_11415	ENOG41067V3	Antibiotic biosynthesis monooxygenase
C0Z11_11425	ENOG4107SFI	Major Facilitator superfamily
C0Z11_11430	ENOG4105CMT	Dihydroxyacetone kinase
C0Z11_11435	ENOG4108UTZ	Dihydroxyacetone kinase
C0Z11_11440	ENOG4105VDH	Dihydroxyacetone kinase
C0Z11_11480	ENOG4105CUB	amino acid
C0Z11_11485	ENOG4106V2I	dimethylaminohydrolase
C0Z11_11490	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C0Z11_11520	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
C0Z11_11525	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C0Z11_11570	ENOG4108IV0	ABC, transporter
C0Z11_11575	ENOG4105C0Z	ABC transporter
C0Z11_11580	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C0Z11_11585	ENOG4105C32	Amino acid ABC transporter (Permease)
C0Z11_11590	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
C0Z11_11615	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C0Z11_11620	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C0Z11_11630	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C0Z11_11650	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
C0Z11_11660	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C0Z11_11670	ENOG4105HDK	L-asparaginase
C0Z11_11680	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
C0Z11_11685	ENOG4105C8V	SAICAR synthetase
C0Z11_11690	ENOG4105D3R	alkyl hydroperoxide reductase
C0Z11_11695	ENOG4108JU3	Alkyl hydroperoxide reductase
C0Z11_11700	ENOG4105C5Q	Transcriptional regulator
C0Z11_11705	ENOG4105C83	adenylosuccinate lyase
C0Z11_11715	ENOG4108RNG	Permease of the drug metabolite transporter
C0Z11_11720	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C0Z11_11735	ENOG4105XTG	Pfam:DUF156
C0Z11_11740	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C0Z11_11750	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
C0Z11_11785	ENOG4105K63	Thioredoxin
C0Z11_11790	ENOG4105C3M	thioredoxin reductase
C0Z11_11810	ENOG4108VX5	3-methyladenine DNA glycosylase
C0Z11_11820	ENOG4105CQ7	ATP-dependent helicase
C0Z11_11835	ENOG4105KHC	sulfurtransferase
C0Z11_11860	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
C0Z11_11865	ENOG4105E2K	Glycosyl transferase (Group 1
C0Z11_11875	ENOG4108IJ1	Dehydrogenase
C0Z11_11880	ENOG4105CDA	abc transporter atp-binding protein
C0Z11_11885	ENOG4107UBR	Extracellular solute-binding protein family 3
C0Z11_11890	ENOG4108Q1T	ABC transporter
C0Z11_11895	ENOG4105DRP	amino acid AbC transporter
C0Z11_11900	ENOG4105DE4	1-phosphofructokinase
C0Z11_11930	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C0Z11_11970	ENOG4105BZ4	penicillin-binding protein
C0Z11_12005	ENOG4108IG5	Transcriptional regulator
C0Z11_12015	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C0Z11_12060	ENOG4105IJJ	transcriptional regulator, crp fnr family
C0Z11_12100	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C0Z11_12115	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
C0Z11_12120	ENOG4106A3M	Cytochrome p-450
C0Z11_12135	ENOG4105CVN	desaturase
C0Z11_12155	ENOG4105EWK	phytoene
C0Z11_12160	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C0Z11_12185	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C0Z11_12190	ENOG4108IRC	dna polymerase iii
C0Z11_12210	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
C0Z11_12230	ENOG4105DCF	alanine dehydrogenase
C0Z11_12235	ENOG4108MGF	sugar kinase
C0Z11_12270	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C0Z11_12280	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C0Z11_12285	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C0Z11_12290	ENOG4105CHR	reductase
C0Z11_12295	ENOG4107QKG	PfaD family
C0Z11_12350	ENOG4107QRT	dEAD DEAH box helicase
C0Z11_12365	ENOG4105C0D	helicase
C0Z11_12380	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
C0Z11_12390	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
C0Z11_12400	ENOG4105EHZ	conserved protein UCP016719
C0Z11_12410	ENOG4105D44	asparaginase
C0Z11_12415	ENOG4105F8D	glycoside hydrolase family 4
C0Z11_12420	ENOG4105CSR	polyphosphate kinase 2
C0Z11_12430	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
C0Z11_12435	ENOG4105BZ7	extracellular solute-binding protein family 1
C0Z11_12440	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
C0Z11_12445	ENOG4105ETE	Transcriptional regulator (LacI family
C0Z11_12455	ENOG4105KT7	mgtC SapB transporter
C0Z11_12470	ENOG4108UW5	maltose o-acetyltransferase
C0Z11_12475	ENOG4108RFG	Tetr family transcriptional regulator
C0Z11_12500	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
C0Z11_12505	ENOG4105KT7	mgtC SapB transporter
C0Z11_12510	ENOG4105ETE	Transcriptional regulator (LacI family
C0Z11_12565	ENOG41082SX	arsR family transcriptional regulator
C0Z11_12570	ENOG4105CSV	Glutaminase
C0Z11_12575	ENOG4105DZW	Dipeptidase
C0Z11_12590	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
C0Z11_12595	ENOG4105CH6	catalase
C0Z11_12615	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C0Z11_12645	ENOG4105Y3U	Transglycosylase-associated protein
C0Z11_12650	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C0Z11_12655	ENOG4105CSH	Transporter
C0Z11_12665	ENOG41086KC	Transcriptional regulator
C0Z11_12675	ENOG4105Y3U	Transglycosylase-associated protein
C0Z11_12680	ENOG4108HHA	Transketolase
C0Z11_12685	ENOG4107Y5I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C0Z11_12690	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
C0Z11_12695	ENOG4105CSH	Transporter
C0Z11_12700	ENOG4105DWF	phosphomethylpyrimidine kinase
C0Z11_12705	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C0Z11_12710	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C0Z11_12715	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C0Z11_12720	ENOG4107YH6	single-stranded DNA-binding protein
C0Z11_12725	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
C0Z11_12730	ENOG4105DBE	peroxidase
C0Z11_12750	ENOG4108IQE	Amp-dependent synthetase and ligase
C0Z11_12760	ENOG4108IXY	short-chain dehydrogenase reductase
C0Z11_12790	ENOG4105M0C	cytoplasmic protein
C0Z11_12800	ENOG4105CQB	FAD linked oxidase domain protein
C0Z11_12810	ENOG4105WH1	Two component transcriptional regulator luxr family
C0Z11_12815	ENOG4105CJ1	ABC, transporter
C0Z11_12825	ENOG4105BZU	Histidine kinase
C0Z11_12840	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C0Z11_12845	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C0Z11_12850	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
C0Z11_12855	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
C0Z11_12920	ENOG4108KQ5	Integrase catalytic subunit
C0Z11_12940	ENOG4107R73	Mate efflux family protein
C0Z11_12950	ENOG4108TFM	Kinase, PfkB family
C0Z11_12955	ENOG4108Z66	YbaK ebsC protein
C0Z11_12980	ENOG4105D7K	pfkb domain protein
C0Z11_12995	ENOG4105CUC	YeeE YedE family protein
C0Z11_13005	ENOG4105IDI	abc transporter atp-binding protein
C0Z11_13010	ENOG4107TPY	serine threonine protein kinase
C0Z11_13020	ENOG4105CTQ	phosphohexokinase
C0Z11_13025	ENOG4105E5G	Alpha beta hydrolase fold
C0Z11_13030	ENOG4105BZU	Histidine kinase
C0Z11_13035	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C0Z11_13045	ENOG4107RCV	ABC transporter, permease
C0Z11_13050	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C0Z11_13055	ENOG4105CXY	transporter
C0Z11_13095	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C0Z11_13115	ENOG4105CAG	UPF0210 protein
C0Z11_13130	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C0Z11_13145	ENOG4105D8X	mechanosensitive ion channel
C0Z11_13150	ENOG4105BZW	Glycerate kinase
C0Z11_13155	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C0Z11_13170	ENOG4105D9P	serine threonine protein kinase
C0Z11_13185	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C0Z11_13190	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C0Z11_13195	ENOG4107RHR	regulatoR
C0Z11_13220	ENOG4105K63	Thioredoxin
C0Z11_13245	ENOG4105CSV	Glutaminase
C0Z11_13265	ENOG4108XG2	Histidine kinase
C0Z11_13275	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
C0Z11_13290	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C0Z11_13295	ENOG4105CPF	Cell wall formation (By similarity)
C0Z11_13305	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C0Z11_13315	ENOG4108KQ5	Integrase catalytic subunit
C0Z11_13320	ENOG4105FA0	parb-like partition protein
C0Z11_13325	ENOG4107QJE	Chromosome Partitioning Protein
C0Z11_13330	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C0Z11_13340	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C0Z11_13355	ENOG41084CH	50S ribosomal protein l34