locus-tag	class	description
ACPOL_0004	COG1069	ribulokinase activity
ACPOL_0010	COG1174	glycine betaine transport
ACPOL_0015	COG0126	phosphoglycerate kinase activity
ACPOL_0020	COG0149	triose-phosphate isomerase activity
ACPOL_0023	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACPOL_0023	COG0519	Catalyzes the synthesis of GMP from XMP
ACPOL_0025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACPOL_0026	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACPOL_0032	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACPOL_0033	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACPOL_0035	COG0697	spore germination
ACPOL_0039	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACPOL_0039	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACPOL_0040	COG1917	Cupin 2, conserved barrel domain protein
ACPOL_0040	COG4977	sequence-specific DNA binding
ACPOL_0047	COG1040	competence protein
ACPOL_0051	COG0783	Belongs to the Dps family
ACPOL_0054	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACPOL_0056	COG1030	water channel activity
ACPOL_0057	COG0330	HflC and HflK could
ACPOL_0059	COG2937	Belongs to the GPAT DAPAT family
ACPOL_0060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACPOL_0061	COG1619	proteins homologs of microcin C7 resistance protein MccF
ACPOL_0062	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACPOL_0066	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACPOL_0071	COG4206	TonB-dependent receptor
ACPOL_0072	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACPOL_0072	COG0321	lipoyl(octanoyl) transferase activity
ACPOL_0073	COG0196	riboflavin kinase activity
ACPOL_0075	COG0653	protein targeting
ACPOL_0078	COG3609	addiction module antidote protein, CC2985 family
ACPOL_0081	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACPOL_0087	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACPOL_0088	COG0463	Glycosyl transferase, family 2
ACPOL_0089	COG0676	glucose-6-phosphate 1-epimerase activity
ACPOL_0090	COG0375	protein maturation
ACPOL_0091	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ACPOL_0092	COG0298	carbon dioxide binding
ACPOL_0093	COG0409	Hydrogenase expression formation protein
ACPOL_0094	COG0309	Hydrogenase expression formation protein (HypE)
ACPOL_0097	COG1960	acyl-CoA dehydrogenase activity
ACPOL_0107	COG0626	cystathionine gamma-synthase activity
ACPOL_0108	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACPOL_0115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACPOL_0116	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACPOL_0118	COG0577	efflux transmembrane transporter activity
ACPOL_0118	COG1136	(ABC) transporter
ACPOL_0119	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACPOL_0121	COG0745	RESPONSE REGULATOR receiver
ACPOL_0124	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACPOL_0131	COG1749	Flagellar hook protein flgE
ACPOL_0137	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACPOL_0140	COG1558	bacterial-type flagellum-dependent cell motility
ACPOL_0141	COG1815	bacterial-type flagellum-dependent cell motility
ACPOL_0142	COG3604	Transcriptional regulator
ACPOL_0144	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACPOL_0145	COG3118	belongs to the thioredoxin family
ACPOL_0146	COG0083	homoserine kinase activity
ACPOL_0147	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACPOL_0148	COG1136	(ABC) transporter
ACPOL_0148	COG0577	efflux transmembrane transporter activity
ACPOL_0149	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACPOL_0153	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACPOL_0154	COG0163	prenyltransferase activity
ACPOL_0165	COG0148	phosphopyruvate hydratase activity
ACPOL_0167	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACPOL_0174	COG0539	negative regulation of cytoplasmic translation
ACPOL_0175	COG4297	protein containing double-stranded beta helix domain
ACPOL_0181	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACPOL_0182	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACPOL_0184	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACPOL_0186	COG0303	'Molybdopterin
ACPOL_0188	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ACPOL_0189	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACPOL_0198	COG1201	RNA secondary structure unwinding
ACPOL_0201	COG3608	succinylglutamate desuccinylase aspartoacylase
ACPOL_0201	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ACPOL_0203	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACPOL_0204	COG0315	cyclic pyranopterin monophosphate synthase activity
ACPOL_0205	COG0314	molybdopterin synthase activity
ACPOL_0206	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACPOL_0209	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACPOL_0210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACPOL_0216	COG3383	formate dehydrogenase (NAD+) activity
ACPOL_0221	COG0546	phosphoglycolate phosphatase activity
ACPOL_0222	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACPOL_0223	COG0456	acetyltransferase
ACPOL_0226	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACPOL_0229	COG0347	Belongs to the P(II) protein family
ACPOL_0230	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACPOL_0237	COG1268	BioY protein
ACPOL_0243	COG0631	protein serine/threonine phosphatase activity
ACPOL_0246	COG2199	diguanylate cyclase activity
ACPOL_0247	COG1201	RNA secondary structure unwinding
ACPOL_0250	COG0582	viral genome integration into host DNA
ACPOL_0255	COG0305	Participates in initiation and elongation during chromosome replication
ACPOL_0263	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0266	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0270	COG0662	Cupin 2, conserved barrel domain protein
ACPOL_0270	COG2207	Transcriptional regulator
ACPOL_0271	COG0745	RESPONSE REGULATOR receiver
ACPOL_0272	COG1309	transcriptional regulator
ACPOL_0282	COG0477	Major facilitator Superfamily
ACPOL_0286	COG2267	carboxylic ester hydrolase activity
ACPOL_0287	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACPOL_0289	COG0492	ferredoxin-NADP+ reductase activity
ACPOL_0298	COG2197	response regulator
ACPOL_0313	COG3344	reverse transcriptase
ACPOL_0328	COG0572	uridine kinase
ACPOL_0347	COG1472	Belongs to the glycosyl hydrolase 3 family
ACPOL_0348	COG3693	PFAM glycoside hydrolase, family 10
ACPOL_0348	COG2382	esterase
ACPOL_0352	COG2208	phosphoserine phosphatase activity
ACPOL_0353	COG1295	ribonuclease BN
ACPOL_0354	COG1278	Cold shock
ACPOL_0356	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACPOL_0360	COG2272	Belongs to the type-B carboxylesterase lipase family
ACPOL_0364	COG0142	geranyltranstransferase activity
ACPOL_0365	COG2151	metal-sulfur cluster biosynthetic enzyme
ACPOL_0366	COG1278	Cold shock
ACPOL_0370	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ACPOL_0375	COG1796	DNA polymerase
ACPOL_0375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ACPOL_0380	COG0281	malic enzyme
ACPOL_0381	COG0114	fumarate hydratase activity
ACPOL_0393	COG1418	mRNA catabolic process
ACPOL_0401	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACPOL_0402	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACPOL_0404	COG3345	alpha-galactosidase
ACPOL_0408	COG2271	Major facilitator Superfamily
ACPOL_0409	COG0363	glucosamine-6-phosphate deaminase activity
ACPOL_0410	COG2222	sugar isomerase
ACPOL_0411	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACPOL_0417	COG0640	Transcriptional regulator
ACPOL_0424	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ACPOL_0425	COG1733	regulation of RNA biosynthetic process
ACPOL_0431	COG0745	RESPONSE REGULATOR receiver
ACPOL_0433	COG0824	Thioesterase
ACPOL_0434	COG0750	zinc metalloprotease
ACPOL_0436	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACPOL_0439	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACPOL_0443	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACPOL_0449	COG0667	Aldo Keto reductase
ACPOL_0456	COG2201	protein-glutamate methylesterase activity
ACPOL_0457	COG1846	Transcriptional regulator
ACPOL_0458	COG2353	YceI-like domain
ACPOL_0460	COG2814	Major facilitator Superfamily
ACPOL_0469	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACPOL_0470	COG1872	DUF167
ACPOL_0471	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACPOL_0477	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0481	COG1899	peptidyl-lysine modification to peptidyl-hypusine
ACPOL_0482	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACPOL_0483	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACPOL_0485	COG0154	amidase activity
ACPOL_0506	COG4962	Type ii secretion system protein e
ACPOL_0515	COG1196	nuclear chromosome segregation
ACPOL_0516	COG4191	Histidine kinase
ACPOL_0526	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0528	COG3300	MHYT domain
ACPOL_0528	COG5001	Diguanylate cyclase
ACPOL_0530	COG3548	integral membrane protein
ACPOL_0533	COG3145	DNA-N1-methyladenine dioxygenase activity
ACPOL_0535	COG2169	Transcriptional regulator
ACPOL_0535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACPOL_0536	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACPOL_0555	COG4221	oxidoreductase activity
ACPOL_0564	COG1012	belongs to the aldehyde dehydrogenase family
ACPOL_0566	COG0583	DNA-binding transcription factor activity
ACPOL_0583	COG2226	methyltransferase
ACPOL_0586	COG2311	Membrane
ACPOL_0591	COG4221	oxidoreductase activity
ACPOL_0592	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0606	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACPOL_0607	COG0667	Aldo Keto reductase
ACPOL_0609	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0611	COG0596	Alpha beta hydrolase
ACPOL_0613	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACPOL_0619	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0622	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0624	COG1253	flavin adenine dinucleotide binding
ACPOL_0634	COG0583	DNA-binding transcription factor activity
ACPOL_0640	COG0582	viral genome integration into host DNA
ACPOL_0650	COG3590	peptidase
ACPOL_0654	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0655	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0656	COG0583	DNA-binding transcription factor activity
ACPOL_0659	COG2197	response regulator
ACPOL_0665	COG1064	alcohol dehydrogenase
ACPOL_0666	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_0667	COG1063	alcohol dehydrogenase
ACPOL_0668	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_0672	COG3850	Histidine kinase
ACPOL_0680	COG1063	alcohol dehydrogenase
ACPOL_0681	COG1073	alpha beta
ACPOL_0698	COG1733	regulation of RNA biosynthetic process
ACPOL_0703	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACPOL_0705	COG0477	Major facilitator Superfamily
ACPOL_0710	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0711	COG4977	sequence-specific DNA binding
ACPOL_0713	COG2197	response regulator
ACPOL_0721	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_0725	COG0596	Alpha beta hydrolase
ACPOL_0727	COG2311	Membrane
ACPOL_0728	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACPOL_0730	COG0114	fumarate hydratase activity
ACPOL_0739	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACPOL_0745	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0746	COG4977	sequence-specific DNA binding
ACPOL_0750	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0754	COG4221	oxidoreductase activity
ACPOL_0756	COG0577	efflux transmembrane transporter activity
ACPOL_0756	COG1136	(ABC) transporter
ACPOL_0757	COG1695	Transcriptional regulator
ACPOL_0776	COG0438	transferase activity, transferring glycosyl groups
ACPOL_0782	COG0297	glycogen (starch) synthase activity
ACPOL_0801	COG0445	tRNA wobble uridine modification
ACPOL_0810	COG4644	lycopene metabolic process
ACPOL_0811	COG4585	Histidine kinase
ACPOL_0820	COG3850	Histidine kinase
ACPOL_0821	COG2197	response regulator
ACPOL_0823	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACPOL_0824	COG1538	Outer membrane efflux protein
ACPOL_0830	COG0798	PFAM Bile acid sodium symporter
ACPOL_0834	COG0346	lactoylglutathione lyase activity
ACPOL_0839	COG0006	proline dipeptidase activity
ACPOL_0842	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACPOL_0846	COG0577	efflux transmembrane transporter activity
ACPOL_0846	COG1136	(ABC) transporter
ACPOL_0863	COG3237	CsbD-like
ACPOL_0867	COG0629	single-stranded DNA binding
ACPOL_0876	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0879	COG2267	carboxylic ester hydrolase activity
ACPOL_0882	COG0405	Gamma-glutamyltransferase
ACPOL_0897	COG2197	response regulator
ACPOL_0898	COG4585	Histidine kinase
ACPOL_0905	COG2160	L-arabinose isomerase activity
ACPOL_0906	COG1501	Belongs to the glycosyl hydrolase 31 family
ACPOL_0908	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACPOL_0912	COG2080	2 iron, 2 sulfur cluster binding
ACPOL_0913	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_0914	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACPOL_0920	COG0714	Associated with various cellular activities
ACPOL_0926	COG2132	Multicopper oxidase
ACPOL_0945	COG2801	Transposase and inactivated derivatives
ACPOL_0946	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_0966	COG3316	Transposase and inactivated derivatives
ACPOL_0979	COG1136	(ABC) transporter
ACPOL_0982	COG0450	alkyl hydroperoxide reductase
ACPOL_0984	COG3876	Protein conserved in bacteria
ACPOL_0986	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ACPOL_0991	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACPOL_0994	COG2897	thiosulfate sulfurtransferase activity
ACPOL_0997	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1005	COG2197	response regulator
ACPOL_1007	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACPOL_1010	COG0463	Glycosyl transferase, family 2
ACPOL_1011	COG1819	glycosyl
ACPOL_1012	COG1609	Transcriptional regulator
ACPOL_1014	COG1104	cysteine desulfurase activity
ACPOL_1016	COG0482	sulfurtransferase activity
ACPOL_1029	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACPOL_1035	COG0443	Heat shock 70 kDa protein
ACPOL_1037	COG0484	heat shock protein binding
ACPOL_1038	COG0789	Transcriptional regulator
ACPOL_1041	COG0577	efflux transmembrane transporter activity
ACPOL_1041	COG1136	(ABC) transporter
ACPOL_1047	COG0217	transcriptional regulatory protein
ACPOL_1049	COG0628	permease
ACPOL_1051	COG0659	secondary active sulfate transmembrane transporter activity
ACPOL_1053	COG0047	phosphoribosylformylglycinamidine synthase activity
ACPOL_1054	COG4464	protein tyrosine phosphatase activity
ACPOL_1055	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1056	COG2197	response regulator
ACPOL_1057	COG0673	inositol 2-dehydrogenase activity
ACPOL_1061	COG0546	phosphoglycolate phosphatase activity
ACPOL_1067	COG1706	bacterial-type flagellum-dependent cell motility
ACPOL_1068	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ACPOL_1070	COG4786	Flagellar basal body rod
ACPOL_1071	COG4786	Flagellar basal body rod
ACPOL_1074	COG0475	glutathione-regulated potassium exporter activity
ACPOL_1075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACPOL_1076	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACPOL_1078	COG3361	conserved protein (COG2071)
ACPOL_1082	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1083	COG1295	ribonuclease BN
ACPOL_1087	COG1476	TRANSCRIPTIONal
ACPOL_1089	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACPOL_1091	COG0512	Glutamine amidotransferase of anthranilate synthase
ACPOL_1093	COG0583	DNA-binding transcription factor activity
ACPOL_1096	COG2855	membrane
ACPOL_1098	COG0730	response to heat
ACPOL_1100	COG2815	serine threonine protein kinase
ACPOL_1100	COG0515	serine threonine protein kinase
ACPOL_1101	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1106	COG0642	Histidine kinase
ACPOL_1109	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACPOL_1110	COG0473	3-isopropylmalate dehydrogenase activity
ACPOL_1111	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACPOL_1112	COG0066	3-isopropylmalate dehydratase activity
ACPOL_1113	COG0129	dihydroxy-acid dehydratase activity
ACPOL_1114	COG0028	Belongs to the TPP enzyme family
ACPOL_1115	COG0440	acetolactate synthase activity
ACPOL_1116	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACPOL_1131	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACPOL_1134	COG1595	DNA-templated transcription, initiation
ACPOL_1136	COG1278	Cold shock
ACPOL_1140	COG0006	proline dipeptidase activity
ACPOL_1141	COG1070	Carbohydrate kinase
ACPOL_1145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACPOL_1146	COG0842	Transport permease protein
ACPOL_1150	COG4221	oxidoreductase activity
ACPOL_1151	COG2084	Dehydrogenase
ACPOL_1153	COG2197	response regulator
ACPOL_1155	COG1674	ftsk spoiiie
ACPOL_1156	COG1968	undecaprenyl-diphosphatase activity
ACPOL_1159	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACPOL_1160	COG2171	N-acyltransferase activity
ACPOL_1162	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACPOL_1164	COG0527	aspartate kinase activity
ACPOL_1167	COG0473	3-isopropylmalate dehydrogenase activity
ACPOL_1168	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACPOL_1172	COG0741	lytic transglycosylase activity
ACPOL_1173	COG0561	phosphatase activity
ACPOL_1174	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACPOL_1177	COG3132	Protein of unknown function, DUF480
ACPOL_1188	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACPOL_1189	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACPOL_1190	COG1832	CoA-binding protein
ACPOL_1192	COG1193	negative regulation of DNA recombination
ACPOL_1196	COG1136	(ABC) transporter
ACPOL_1196	COG0577	efflux transmembrane transporter activity
ACPOL_1200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACPOL_1201	COG0494	nUDIX hydrolase
ACPOL_1205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACPOL_1209	COG3387	PFAM Glycoside hydrolase 15-related
ACPOL_1212	COG2197	response regulator
ACPOL_1214	COG3394	polysaccharide catabolic process
ACPOL_1215	COG0438	transferase activity, transferring glycosyl groups
ACPOL_1216	COG3275	phosphorelay sensor kinase activity
ACPOL_1219	COG0494	nUDIX hydrolase
ACPOL_1221	COG4974	Belongs to the 'phage' integrase family
ACPOL_1222	COG4974	Belongs to the 'phage' integrase family
ACPOL_1230	COG3409	Peptidoglycan-binding domain 1 protein
ACPOL_1230	COG0793	Belongs to the peptidase S41A family
ACPOL_1236	COG1874	Beta-galactosidase
ACPOL_1238	COG0018	arginyl-trna synthetase
ACPOL_1240	COG0084	hydrolase, TatD family'
ACPOL_1241	COG1666	GTP binding
ACPOL_1242	COG0142	geranyltranstransferase activity
ACPOL_1247	COG3459	Glycosyltransferase 36 associated
ACPOL_1247	COG3459	Glycosyltransferase 36 associated
ACPOL_1248	COG2208	phosphoserine phosphatase activity
ACPOL_1260	COG0489	protein tyrosine kinase activity
ACPOL_1266	COG1063	alcohol dehydrogenase
ACPOL_1268	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACPOL_1272	COG1657	PFAM Prenyltransferase squalene oxidase
ACPOL_1273	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACPOL_1275	COG0497	DNA recombination
ACPOL_1279	COG3119	arylsulfatase activity
ACPOL_1280	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ACPOL_1281	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACPOL_1285	COG1793	dna ligase
ACPOL_1286	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACPOL_1287	COG2890	protein-(glutamine-N5) methyltransferase activity
ACPOL_1288	COG0542	response to heat
ACPOL_1294	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACPOL_1295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACPOL_1299	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACPOL_1301	COG0495	leucyl-tRNA aminoacylation
ACPOL_1307	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ACPOL_1312	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACPOL_1316	COG2267	carboxylic ester hydrolase activity
ACPOL_1318	COG3447	MASE1 domain protein
ACPOL_1318	COG5001	Diguanylate cyclase
ACPOL_1318	COG5002	protein histidine kinase activity
ACPOL_1319	COG4251	negative regulation of phosphorylation
ACPOL_1320	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACPOL_1322	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ACPOL_1323	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACPOL_1326	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACPOL_1329	COG0124	histidyl-tRNA synthetase
ACPOL_1330	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACPOL_1332	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACPOL_1336	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1337	COG1196	nuclear chromosome segregation
ACPOL_1343	COG2223	nitrite transmembrane transporter activity
ACPOL_1346	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_1347	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACPOL_1347	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACPOL_1348	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACPOL_1348	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACPOL_1349	COG1127	ABC transporter
ACPOL_1353	COG0300	oxidoreductase activity
ACPOL_1354	COG0339	signal peptide processing
ACPOL_1356	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACPOL_1358	COG0802	atpase or kinase
ACPOL_1359	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACPOL_1359	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACPOL_1360	COG0768	penicillin binding
ACPOL_1361	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACPOL_1363	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACPOL_1364	COG1446	asparaginase
ACPOL_1365	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ACPOL_1367	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACPOL_1369	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACPOL_1371	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ACPOL_1388	COG1595	DNA-templated transcription, initiation
ACPOL_1393	COG2124	cytochrome p450
ACPOL_1395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACPOL_1399	COG1819	glycosyl
ACPOL_1400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACPOL_1401	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACPOL_1403	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACPOL_1404	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1411	COG0300	oxidoreductase activity
ACPOL_1412	COG1733	regulation of RNA biosynthetic process
ACPOL_1419	COG1695	Transcriptional regulator
ACPOL_1423	COG0009	L-threonylcarbamoyladenylate synthase
ACPOL_1424	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACPOL_1426	COG0531	amino acid
ACPOL_1439	COG0745	RESPONSE REGULATOR receiver
ACPOL_1442	COG0571	ribonuclease III activity
ACPOL_1443	COG0681	Belongs to the peptidase S26 family
ACPOL_1447	COG1846	Transcriptional regulator
ACPOL_1450	COG0251	oxidation-reduction process
ACPOL_1452	COG1609	Transcriptional regulator
ACPOL_1453	COG2255	four-way junction helicase activity
ACPOL_1455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACPOL_1458	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACPOL_1460	COG0742	ribosomal rna small subunit methyltransferase
ACPOL_1462	COG1764	response to oxidative stress
ACPOL_1463	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACPOL_1465	COG0739	heme binding
ACPOL_1470	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACPOL_1471	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACPOL_1474	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACPOL_1479	COG1064	alcohol dehydrogenase
ACPOL_1481	COG0825	malonyl-CoA metabolic process
ACPOL_1483	COG1012	belongs to the aldehyde dehydrogenase family
ACPOL_1486	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACPOL_1487	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
ACPOL_1488	COG0167	dihydroorotate dehydrogenase activity
ACPOL_1490	COG3684	Belongs to the aldolase LacD family
ACPOL_1493	COG2205	protein histidine kinase activity
ACPOL_1494	COG2204	response regulator
ACPOL_1497	COG3685	Protein conserved in bacteria
ACPOL_1498	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACPOL_1499	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACPOL_1501	COG1058	Belongs to the CinA family
ACPOL_1501	COG1546	Belongs to the CinA family
ACPOL_1502	COG1501	Belongs to the glycosyl hydrolase 31 family
ACPOL_1503	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACPOL_1504	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACPOL_1505	COG0768	penicillin binding
ACPOL_1507	COG0275	rRNA processing
ACPOL_1508	COG2001	Belongs to the MraZ family
ACPOL_1510	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ACPOL_1512	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACPOL_1520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACPOL_1521	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACPOL_1531	COG0681	Belongs to the peptidase S26 family
ACPOL_1539	COG3279	Response regulator of the LytR AlgR family
ACPOL_1542	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ACPOL_1546	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ACPOL_1546	COG0644	oxidoreductase
ACPOL_1547	COG3706	GGDEF domain
ACPOL_1547	COG0745	RESPONSE REGULATOR receiver
ACPOL_1549	COG4555	ABC transporter
ACPOL_1554	COG1595	DNA-templated transcription, initiation
ACPOL_1556	COG1950	PFAM Membrane protein of
ACPOL_1558	COG1285	pathogenesis
ACPOL_1563	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACPOL_1564	COG2226	methyltransferase
ACPOL_1566	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1567	COG1914	H( )-stimulated, divalent metal cation uptake system
ACPOL_1573	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACPOL_1574	COG0154	amidase activity
ACPOL_1580	COG4999	Histidine kinase
ACPOL_1580	COG2205	protein histidine kinase activity
ACPOL_1580	COG3850	Histidine kinase
ACPOL_1580	COG3437	response regulator, receiver
ACPOL_1581	COG4993	Dehydrogenase
ACPOL_1586	COG0531	amino acid
ACPOL_1587	COG2271	Major facilitator Superfamily
ACPOL_1591	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
ACPOL_1593	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACPOL_1594	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACPOL_1596	COG2308	Evidence 4 Homologs of previously reported genes of
ACPOL_1598	COG1305	Transglutaminase-like
ACPOL_1599	COG0300	oxidoreductase activity
ACPOL_1601	COG0546	phosphoglycolate phosphatase activity
ACPOL_1601	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACPOL_1602	COG0433	COG0433 Predicted ATPase
ACPOL_1608	COG2814	Major facilitator Superfamily
ACPOL_1615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACPOL_1616	COG0726	polysaccharide deacetylase
ACPOL_1617	COG1428	Deoxynucleoside kinase
ACPOL_1618	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACPOL_1619	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACPOL_1620	COG2094	Belongs to the DNA glycosylase MPG family
ACPOL_1621	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACPOL_1624	COG0151	Belongs to the GarS family
ACPOL_1627	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACPOL_1631	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACPOL_1635	COG4956	integral membrane protein (PIN domain superfamily)
ACPOL_1637	COG4191	Histidine kinase
ACPOL_1643	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACPOL_1651	COG0437	4 iron, 4 sulfur cluster binding
ACPOL_1654	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACPOL_1656	COG0739	heme binding
ACPOL_1658	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACPOL_1661	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACPOL_1661	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACPOL_1665	COG0366	Alpha amylase catalytic
ACPOL_1667	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACPOL_1673	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACPOL_1675	COG0359	binds to the 23S rRNA
ACPOL_1676	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACPOL_1677	COG0360	Binds together with S18 to 16S ribosomal RNA
ACPOL_1678	COG0193	aminoacyl-tRNA hydrolase activity
ACPOL_1679	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACPOL_1680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACPOL_1681	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACPOL_1684	COG0017	Asparaginyl-tRNA synthetase
ACPOL_1685	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACPOL_1686	COG1722	exodeoxyribonuclease VII activity
ACPOL_1693	COG0288	reversible hydration of carbon dioxide
ACPOL_1697	COG1982	Orn Lys Arg decarboxylase major
ACPOL_1703	COG0577	efflux transmembrane transporter activity
ACPOL_1703	COG1136	(ABC) transporter
ACPOL_1704	COG2376	Dihydroxyacetone kinase
ACPOL_1710	COG1695	Transcriptional regulator
ACPOL_1713	COG2032	superoxide dismutase activity
ACPOL_1714	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACPOL_1717	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACPOL_1721	COG0606	chelatase, subunit chli
ACPOL_1722	COG1472	Belongs to the glycosyl hydrolase 3 family
ACPOL_1723	COG1760	l-serine dehydratase
ACPOL_1726	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACPOL_1727	COG0484	heat shock protein binding
ACPOL_1728	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACPOL_1729	COG1420	regulation of RNA biosynthetic process
ACPOL_1730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACPOL_1730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACPOL_1732	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ACPOL_1734	COG1335	isochorismatase
ACPOL_1736	COG4152	abc transporter atp-binding protein
ACPOL_1737	COG0110	maltose O-acetyltransferase activity
ACPOL_1738	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACPOL_1740	COG3590	peptidase
ACPOL_1743	COG0463	Glycosyl transferase, family 2
ACPOL_1744	COG0616	signal peptide processing
ACPOL_1745	COG0776	regulation of translation
ACPOL_1754	COG3852	Histidine kinase
ACPOL_1756	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACPOL_1757	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ACPOL_1758	COG1595	DNA-templated transcription, initiation
ACPOL_1761	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_1763	COG1836	PFAM Integral membrane protein DUF92
ACPOL_1765	COG0583	DNA-binding transcription factor activity
ACPOL_1767	COG2957	Belongs to the agmatine deiminase family
ACPOL_1768	COG0590	tRNA wobble adenosine to inosine editing
ACPOL_1771	COG0577	efflux transmembrane transporter activity
ACPOL_1771	COG1136	(ABC) transporter
ACPOL_1773	COG0741	lytic transglycosylase activity
ACPOL_1773	COG1388	LysM domain
ACPOL_1774	COG0481	GTPase activity
ACPOL_1777	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACPOL_1780	COG0233	cytoplasmic translational termination
ACPOL_1785	COG0492	ferredoxin-NADP+ reductase activity
ACPOL_1788	COG2815	serine threonine protein kinase
ACPOL_1788	COG0515	serine threonine protein kinase
ACPOL_1797	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ACPOL_1800	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1804	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACPOL_1805	COG0477	Major facilitator Superfamily
ACPOL_1808	COG3345	alpha-galactosidase
ACPOL_1809	COG0673	inositol 2-dehydrogenase activity
ACPOL_1815	COG0372	Belongs to the citrate synthase family
ACPOL_1818	COG1595	DNA-templated transcription, initiation
ACPOL_1822	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1823	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1826	COG0512	Glutamine amidotransferase of anthranilate synthase
ACPOL_1826	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACPOL_1831	COG2124	cytochrome p450
ACPOL_1832	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1833	COG1309	transcriptional regulator
ACPOL_1836	COG2226	methyltransferase
ACPOL_1836	COG1073	alpha beta
ACPOL_1839	COG0596	Alpha beta hydrolase
ACPOL_1844	COG0753	catalase activity
ACPOL_1857	COG0300	oxidoreductase activity
ACPOL_1858	COG0114	fumarate hydratase activity
ACPOL_1859	COG0281	malic enzyme
ACPOL_1869	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACPOL_1870	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACPOL_1871	COG2080	2 iron, 2 sulfur cluster binding
ACPOL_1872	COG1942	4-Oxalocrotonate Tautomerase
ACPOL_1873	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1875	COG1733	regulation of RNA biosynthetic process
ACPOL_1876	COG0667	Aldo Keto reductase
ACPOL_1877	COG0667	Aldo Keto reductase
ACPOL_1890	COG3250	beta-galactosidase activity
ACPOL_1891	COG3685	Protein conserved in bacteria
ACPOL_1899	COG5002	protein histidine kinase activity
ACPOL_1900	COG0745	RESPONSE REGULATOR receiver
ACPOL_1901	COG1247	-acetyltransferase
ACPOL_1902	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACPOL_1903	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_1905	COG0667	Aldo Keto reductase
ACPOL_1907	COG0646	methionine synthase
ACPOL_1907	COG1410	methionine synthase
ACPOL_1912	COG0626	cystathionine gamma-synthase activity
ACPOL_1921	COG0745	RESPONSE REGULATOR receiver
ACPOL_1932	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ACPOL_1937	COG1924	4 iron, 4 sulfur cluster binding
ACPOL_1938	COG0577	efflux transmembrane transporter activity
ACPOL_1943	COG0577	efflux transmembrane transporter activity
ACPOL_1957	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACPOL_1959	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACPOL_1961	COG0416	fatty acid biosynthetic process
ACPOL_1962	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACPOL_1970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACPOL_1970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACPOL_1971	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACPOL_1972	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACPOL_1974	COG0535	radical SAM domain protein
ACPOL_1975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACPOL_1978	COG0328	RNA-DNA hybrid ribonuclease activity
ACPOL_1978	COG0406	alpha-ribazole phosphatase activity
ACPOL_1979	COG1610	YqeY-like protein
ACPOL_1981	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACPOL_1984	COG2040	homocysteine
ACPOL_1985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACPOL_1986	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACPOL_1989	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACPOL_1990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACPOL_1992	COG1595	DNA-templated transcription, initiation
ACPOL_2003	COG1472	Belongs to the glycosyl hydrolase 3 family
ACPOL_2005	COG4585	Histidine kinase
ACPOL_2007	COG2197	response regulator
ACPOL_2009	COG3250	beta-galactosidase activity
ACPOL_2013	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ACPOL_2015	COG0159	tryptophan synthase activity
ACPOL_2016	COG0133	tryptophan synthase activity
ACPOL_2017	COG0135	phosphoribosylanthranilate isomerase activity
ACPOL_2019	COG0134	indole-3-glycerol-phosphate synthase activity
ACPOL_2021	COG1764	response to oxidative stress
ACPOL_2023	COG2234	aminopeptidase activity
ACPOL_2027	COG2226	methyltransferase
ACPOL_2028	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACPOL_2029	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACPOL_2030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACPOL_2031	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACPOL_2032	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACPOL_2033	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACPOL_2036	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACPOL_2038	COG1923	regulation of RNA biosynthetic process
ACPOL_2041	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACPOL_2044	COG1609	Transcriptional regulator
ACPOL_2049	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACPOL_2050	COG0805	protein transport
ACPOL_2053	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACPOL_2054	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACPOL_2055	COG0594	ribonuclease P activity
ACPOL_2057	COG0706	membrane insertase activity
ACPOL_2060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACPOL_2061	COG4251	negative regulation of phosphorylation
ACPOL_2062	COG2197	response regulator
ACPOL_2063	COG3447	MASE1 domain protein
ACPOL_2063	COG5002	protein histidine kinase activity
ACPOL_2063	COG5001	Diguanylate cyclase
ACPOL_2074	COG2814	Major facilitator Superfamily
ACPOL_2083	COG2132	Multicopper oxidase
ACPOL_2087	COG1131	(ABC) transporter
ACPOL_2088	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACPOL_2089	COG0540	Belongs to the ATCase OTCase family
ACPOL_2090	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACPOL_2092	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACPOL_2095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACPOL_2096	COG0776	regulation of translation
ACPOL_2105	COG1695	Transcriptional regulator
ACPOL_2106	COG1131	(ABC) transporter
ACPOL_2111	COG4585	Histidine kinase
ACPOL_2112	COG2197	response regulator
ACPOL_2117	COG0012	GTP binding
ACPOL_2121	COG5000	phosphorelay sensor kinase activity
ACPOL_2122	COG2204	response regulator
ACPOL_2123	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACPOL_2141	COG0515	serine threonine protein kinase
ACPOL_2141	COG2815	serine threonine protein kinase
ACPOL_2144	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACPOL_2148	COG2337	Toxic component of a toxin-antitoxin (TA) module
ACPOL_2153	COG0632	four-way junction helicase activity
ACPOL_2155	COG3046	protein related to deoxyribodipyrimidine photolyase
ACPOL_2157	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACPOL_2159	COG2261	transglycosylase associated protein
ACPOL_2164	COG3830	Belongs to the UPF0237 family
ACPOL_2164	COG0560	Phosphoserine phosphatase
ACPOL_2165	COG0793	Belongs to the peptidase S41A family
ACPOL_2166	COG4702	Belongs to the UPF0303 family
ACPOL_2167	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACPOL_2168	COG3481	metal-dependent phosphohydrolase, HD sub domain
ACPOL_2173	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACPOL_2174	COG0242	peptide deformylase activity
ACPOL_2175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACPOL_2176	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACPOL_2176	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACPOL_2177	COG0515	serine threonine protein kinase
ACPOL_2177	COG2815	serine threonine protein kinase
ACPOL_2179	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACPOL_2184	COG1695	Transcriptional regulator
ACPOL_2185	COG1136	(ABC) transporter
ACPOL_2185	COG0577	efflux transmembrane transporter activity
ACPOL_2193	COG2264	protein methyltransferase activity
ACPOL_2194	COG1215	transferase activity, transferring glycosyl groups
ACPOL_2195	COG0110	maltose O-acetyltransferase activity
ACPOL_2200	COG0028	Belongs to the TPP enzyme family
ACPOL_2203	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2206	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACPOL_2207	COG2089	acid synthase
ACPOL_2209	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACPOL_2211	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACPOL_2212	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACPOL_2212	COG2755	lipolytic protein G-D-S-L family
ACPOL_2216	COG1215	transferase activity, transferring glycosyl groups
ACPOL_2218	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACPOL_2220	COG0564	pseudouridine synthase activity
ACPOL_2224	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACPOL_2226	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_2230	COG0443	Heat shock 70 kDa protein
ACPOL_2231	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACPOL_2234	COG2755	lipolytic protein G-D-S-L family
ACPOL_2234	COG0657	acetylesterase activity
ACPOL_2237	COG3345	alpha-galactosidase
ACPOL_2241	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2243	COG2706	6-phosphogluconolactonase activity
ACPOL_2244	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACPOL_2253	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACPOL_2257	COG2132	Multicopper oxidase
ACPOL_2258	COG0592	DNA-directed DNA polymerase activity
ACPOL_2261	COG0268	Binds directly to 16S ribosomal RNA
ACPOL_2262	COG1228	amidohydrolase
ACPOL_2264	COG1228	amidohydrolase
ACPOL_2267	COG0681	Belongs to the peptidase S26 family
ACPOL_2269	COG1612	heme a metabolic process
ACPOL_2269	COG0109	protoheme IX farnesyltransferase activity
ACPOL_2270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACPOL_2271	COG0745	RESPONSE REGULATOR receiver
ACPOL_2284	COG1475	DNA binding
ACPOL_2285	COG1192	Involved in chromosome partitioning
ACPOL_2286	COG0357	Ribosomal RNA small subunit methyltransferase G
ACPOL_2287	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ACPOL_2290	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACPOL_2292	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACPOL_2297	COG0799	negative regulation of ribosome biogenesis
ACPOL_2298	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACPOL_2299	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACPOL_2301	COG0343	queuine tRNA-ribosyltransferase activity
ACPOL_2302	COG1862	Preprotein translocase
ACPOL_2303	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACPOL_2305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACPOL_2309	COG0848	biopolymer transport protein
ACPOL_2311	COG0439	Biotin carboxylase
ACPOL_2312	COG0511	ligase activity, forming carbon-carbon bonds
ACPOL_2312	COG5016	pyruvate
ACPOL_2318	COG3852	Histidine kinase
ACPOL_2319	COG0402	S-adenosylhomocysteine deaminase activity
ACPOL_2325	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ACPOL_2334	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACPOL_2335	COG4535	Mg2 and Co2 transporter CorC
ACPOL_2336	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACPOL_2338	COG0154	amidase activity
ACPOL_2339	COG1368	sulfuric ester hydrolase activity
ACPOL_2340	COG0488	(ABC) transporter
ACPOL_2345	COG1138	Cytochrome C-type biogenesis protein
ACPOL_2354	COG1132	(ABC) transporter
ACPOL_2355	COG0501	Belongs to the peptidase M48B family
ACPOL_2362	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACPOL_2364	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ACPOL_2365	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2374	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2379	COG1940	carbohydrate kinase activity
ACPOL_2380	COG2814	Major facilitator Superfamily
ACPOL_2383	COG1940	carbohydrate kinase activity
ACPOL_2385	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ACPOL_2395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACPOL_2397	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACPOL_2398	COG0531	amino acid
ACPOL_2401	COG0515	serine threonine protein kinase
ACPOL_2401	COG2815	serine threonine protein kinase
ACPOL_2403	COG0210	DNA helicase
ACPOL_2405	COG1556	Lactate utilization protein
ACPOL_2406	COG1139	Iron-sulfur cluster binding protein
ACPOL_2407	COG0247	lactate metabolic process
ACPOL_2411	COG1309	transcriptional regulator
ACPOL_2420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACPOL_2422	COG1573	uracil-dna glycosylase
ACPOL_2425	COG0673	inositol 2-dehydrogenase activity
ACPOL_2427	COG1560	Kdo2-lipid A biosynthetic process
ACPOL_2429	COG0717	Belongs to the dCTP deaminase family
ACPOL_2433	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACPOL_2434	COG1573	uracil-dna glycosylase
ACPOL_2435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACPOL_2437	COG0194	GDP metabolic process
ACPOL_2438	COG1561	YicC-like family, N-terminal region
ACPOL_2439	COG1132	(ABC) transporter
ACPOL_2440	COG1660	Displays ATPase and GTPase activities
ACPOL_2444	COG1137	ATPase activity
ACPOL_2448	COG1228	amidohydrolase
ACPOL_2450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACPOL_2452	COG2351	hydroxyisourate hydrolase activity
ACPOL_2457	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACPOL_2458	COG0590	tRNA wobble adenosine to inosine editing
ACPOL_2463	COG1132	(ABC) transporter
ACPOL_2467	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACPOL_2469	COG0058	SHG alpha-glucan phosphorylase activity
ACPOL_2474	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACPOL_2474	COG0131	Imidazoleglycerol-phosphate dehydratase
ACPOL_2476	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACPOL_2491	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACPOL_2497	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2498	COG3387	PFAM Glycoside hydrolase 15-related
ACPOL_2502	COG1793	dna ligase
ACPOL_2509	COG1228	amidohydrolase
ACPOL_2510	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACPOL_2512	COG1522	sequence-specific DNA binding
ACPOL_2516	COG1505	serine-type exopeptidase activity
ACPOL_2517	COG2205	protein histidine kinase activity
ACPOL_2518	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACPOL_2519	COG1648	precorrin-2 dehydrogenase activity
ACPOL_2519	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACPOL_2521	COG2855	membrane
ACPOL_2523	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACPOL_2524	COG1609	Transcriptional regulator
ACPOL_2529	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACPOL_2530	COG0573	inorganic phosphate transmembrane transporter activity
ACPOL_2531	COG0581	inorganic phosphate transmembrane transporter activity
ACPOL_2532	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACPOL_2534	COG1074	ATP-dependent DNA helicase activity
ACPOL_2537	COG3265	gluconokinase activity
ACPOL_2540	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ACPOL_2542	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACPOL_2552	COG1295	ribonuclease BN
ACPOL_2571	COG2188	Transcriptional regulator
ACPOL_2578	COG1605	Chorismate mutase
ACPOL_2580	COG2197	response regulator
ACPOL_2581	COG2203	Gaf domain
ACPOL_2581	COG4585	Histidine kinase
ACPOL_2583	COG4191	Histidine kinase
ACPOL_2583	COG2205	protein histidine kinase activity
ACPOL_2583	COG0745	RESPONSE REGULATOR receiver
ACPOL_2587	COG2203	Gaf domain
ACPOL_2587	COG4585	Histidine kinase
ACPOL_2588	COG4447	cellulose binding
ACPOL_2592	COG5002	protein histidine kinase activity
ACPOL_2603	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACPOL_2607	COG2207	Transcriptional regulator
ACPOL_2608	COG0154	amidase activity
ACPOL_2609	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2619	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2626	COG3537	Alpha-1,2-mannosidase
ACPOL_2630	COG1609	Transcriptional regulator
ACPOL_2636	COG0644	oxidoreductase
ACPOL_2638	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACPOL_2641	COG1309	transcriptional regulator
ACPOL_2644	COG0702	epimerase
ACPOL_2654	COG3706	GGDEF domain
ACPOL_2661	COG0629	single-stranded DNA binding
ACPOL_2662	COG0577	efflux transmembrane transporter activity
ACPOL_2662	COG1136	(ABC) transporter
ACPOL_2679	COG3316	Transposase and inactivated derivatives
ACPOL_2687	COG3316	Transposase and inactivated derivatives
ACPOL_2692	COG0583	DNA-binding transcription factor activity
ACPOL_2702	COG1127	ABC transporter
ACPOL_2703	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACPOL_2706	COG3387	PFAM Glycoside hydrolase 15-related
ACPOL_2707	COG0596	Alpha beta hydrolase
ACPOL_2711	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_2719	COG3177	Filamentation induced by cAMP protein fic
ACPOL_2741	COG0667	Aldo Keto reductase
ACPOL_2742	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2744	COG0517	IMP dehydrogenase activity
ACPOL_2745	COG4974	Belongs to the 'phage' integrase family
ACPOL_2749	COG0596	Alpha beta hydrolase
ACPOL_2750	COG0583	DNA-binding transcription factor activity
ACPOL_2758	COG1252	NADH dehydrogenase
ACPOL_2769	COG1940	carbohydrate kinase activity
ACPOL_2773	COG2814	Major facilitator Superfamily
ACPOL_2784	COG3250	beta-galactosidase activity
ACPOL_2785	COG2706	6-phosphogluconolactonase activity
ACPOL_2788	COG3537	Alpha-1,2-mannosidase
ACPOL_2805	COG0517	IMP dehydrogenase activity
ACPOL_2811	COG0517	IMP dehydrogenase activity
ACPOL_2812	COG4974	Belongs to the 'phage' integrase family
ACPOL_2815	COG1309	transcriptional regulator
ACPOL_2821	COG4974	Belongs to the 'phage' integrase family
ACPOL_2822	COG0517	IMP dehydrogenase activity
ACPOL_2824	COG0667	Aldo Keto reductase
ACPOL_2827	COG0583	DNA-binding transcription factor activity
ACPOL_2828	COG0673	inositol 2-dehydrogenase activity
ACPOL_2845	COG1733	regulation of RNA biosynthetic process
ACPOL_2846	COG1475	DNA binding
ACPOL_2850	COG0667	Aldo Keto reductase
ACPOL_2852	COG1733	regulation of RNA biosynthetic process
ACPOL_2858	COG2801	Transposase and inactivated derivatives
ACPOL_2863	COG2226	methyltransferase
ACPOL_2872	COG0596	Alpha beta hydrolase
ACPOL_2873	COG2207	Transcriptional regulator
ACPOL_2878	COG1309	transcriptional regulator
ACPOL_2879	COG1819	glycosyl
ACPOL_2884	COG2132	Multicopper oxidase
ACPOL_2886	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2888	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2893	COG0366	Alpha amylase catalytic
ACPOL_2898	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACPOL_2899	COG1127	ABC transporter
ACPOL_2907	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2910	COG0667	Aldo Keto reductase
ACPOL_2919	COG0667	Aldo Keto reductase
ACPOL_2921	COG0596	Alpha beta hydrolase
ACPOL_2927	COG3250	beta-galactosidase activity
ACPOL_2930	COG3250	beta-galactosidase activity
ACPOL_2932	COG1609	Transcriptional regulator
ACPOL_2934	COG3537	Alpha-1,2-mannosidase
ACPOL_2941	COG3344	reverse transcriptase
ACPOL_2945	COG2801	Transposase and inactivated derivatives
ACPOL_2968	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2971	COG0693	protein deglycase activity
ACPOL_2973	COG1846	Transcriptional regulator
ACPOL_2980	COG0583	DNA-binding transcription factor activity
ACPOL_2984	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_2986	COG3275	phosphorelay sensor kinase activity
ACPOL_2987	COG3279	Response regulator of the LytR AlgR family
ACPOL_2990	COG2910	NAD(P)H-binding
ACPOL_2998	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ACPOL_3004	COG2267	carboxylic ester hydrolase activity
ACPOL_3005	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACPOL_3006	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACPOL_3007	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACPOL_3008	COG1733	regulation of RNA biosynthetic process
ACPOL_3009	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACPOL_3015	COG0076	glutamate decarboxylase activity
ACPOL_3032	COG0517	IMP dehydrogenase activity
ACPOL_3036	COG4974	Belongs to the 'phage' integrase family
ACPOL_3037	COG0517	IMP dehydrogenase activity
ACPOL_3042	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3044	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACPOL_3046	COG4191	Histidine kinase
ACPOL_3047	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACPOL_3050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACPOL_3052	COG2140	Oxalate decarboxylase
ACPOL_3062	COG0028	Belongs to the TPP enzyme family
ACPOL_3069	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACPOL_3073	COG2204	response regulator
ACPOL_3084	COG2814	Major facilitator Superfamily
ACPOL_3086	COG1566	PFAM secretion protein HlyD family protein
ACPOL_3094	COG3344	reverse transcriptase
ACPOL_3096	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_3102	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ACPOL_3103	COG0783	Belongs to the Dps family
ACPOL_3116	COG0708	Exodeoxyribonuclease III
ACPOL_3122	COG0583	DNA-binding transcription factor activity
ACPOL_3123	COG0702	epimerase
ACPOL_3125	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3127	COG2267	carboxylic ester hydrolase activity
ACPOL_3132	COG1733	regulation of RNA biosynthetic process
ACPOL_3136	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_3140	COG1082	Xylose isomerase domain protein TIM barrel
ACPOL_3143	COG2197	response regulator
ACPOL_3144	COG4585	Histidine kinase
ACPOL_3145	COG4977	sequence-specific DNA binding
ACPOL_3146	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3148	COG1063	alcohol dehydrogenase
ACPOL_3149	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3150	COG1228	amidohydrolase
ACPOL_3159	COG1063	alcohol dehydrogenase
ACPOL_3161	COG0667	Aldo Keto reductase
ACPOL_3162	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3172	COG0587	DNA-directed DNA polymerase activity
ACPOL_3174	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACPOL_3179	COG0604	alcohol dehydrogenase
ACPOL_3182	COG0242	peptide deformylase activity
ACPOL_3196	COG1309	transcriptional regulator
ACPOL_3197	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3202	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3205	COG0174	glutamine synthetase
ACPOL_3207	COG0004	ammonium transporteR
ACPOL_3212	COG0515	serine threonine protein kinase
ACPOL_3213	COG0631	protein serine/threonine phosphatase activity
ACPOL_3214	COG0531	amino acid
ACPOL_3215	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3216	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACPOL_3217	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACPOL_3218	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACPOL_3220	COG0477	Major facilitator Superfamily
ACPOL_3221	COG0457	Tetratricopeptide repeat
ACPOL_3223	COG2814	Major facilitator Superfamily
ACPOL_3224	COG0673	inositol 2-dehydrogenase activity
ACPOL_3229	COG4948	Mandelate Racemase Muconate Lactonizing
ACPOL_3232	COG2271	Major facilitator Superfamily
ACPOL_3234	COG0667	Aldo Keto reductase
ACPOL_3236	COG0667	Aldo Keto reductase
ACPOL_3238	COG4948	Mandelate Racemase Muconate Lactonizing
ACPOL_3241	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACPOL_3243	COG2814	Major facilitator Superfamily
ACPOL_3251	COG0583	DNA-binding transcription factor activity
ACPOL_3253	COG1063	alcohol dehydrogenase
ACPOL_3261	COG0741	lytic transglycosylase activity
ACPOL_3265	COG1595	DNA-templated transcription, initiation
ACPOL_3267	COG0009	L-threonylcarbamoyladenylate synthase
ACPOL_3269	COG0470	DNA polymerase III
ACPOL_3270	COG2124	cytochrome p450
ACPOL_3271	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACPOL_3272	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACPOL_3273	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACPOL_3275	COG3240	lipase activity
ACPOL_3276	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACPOL_3279	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACPOL_3297	COG0673	inositol 2-dehydrogenase activity
ACPOL_3300	COG1012	belongs to the aldehyde dehydrogenase family
ACPOL_3306	COG3300	MHYT domain
ACPOL_3306	COG5001	Diguanylate cyclase
ACPOL_3310	COG0640	Transcriptional regulator
ACPOL_3314	COG1538	Outer membrane efflux protein
ACPOL_3331	COG3220	belongs to the UPF0276 family
ACPOL_3347	COG0673	inositol 2-dehydrogenase activity
ACPOL_3352	COG2271	Major facilitator Superfamily
ACPOL_3354	COG0673	inositol 2-dehydrogenase activity
ACPOL_3355	COG0363	glucosamine-6-phosphate deaminase activity
ACPOL_3356	COG1609	Transcriptional regulator
ACPOL_3361	COG1349	DNA-binding transcription factor activity
ACPOL_3379	COG2801	Transposase and inactivated derivatives
ACPOL_3410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACPOL_3413	COG1609	Transcriptional regulator
ACPOL_3414	COG1940	carbohydrate kinase activity
ACPOL_3417	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACPOL_3425	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3427	COG2267	carboxylic ester hydrolase activity
ACPOL_3446	COG2815	serine threonine protein kinase
ACPOL_3446	COG0515	serine threonine protein kinase
ACPOL_3447	COG4974	Belongs to the 'phage' integrase family
ACPOL_3461	COG0305	Participates in initiation and elongation during chromosome replication
ACPOL_3472	COG2814	Major facilitator Superfamily
ACPOL_3474	COG2133	pyrroloquinoline quinone binding
ACPOL_3475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACPOL_3480	COG0577	efflux transmembrane transporter activity
ACPOL_3480	COG1136	(ABC) transporter
ACPOL_3483	COG1295	ribonuclease BN
ACPOL_3485	COG1960	acyl-CoA dehydrogenase activity
ACPOL_3486	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACPOL_3487	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACPOL_3489	COG2204	response regulator
ACPOL_3490	COG5002	protein histidine kinase activity
ACPOL_3493	COG2252	PERMEase
ACPOL_3494	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACPOL_3497	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACPOL_3501	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACPOL_3504	COG1609	Transcriptional regulator
ACPOL_3507	COG2942	2-epimerase
ACPOL_3510	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ACPOL_3513	COG2706	6-phosphogluconolactonase activity
ACPOL_3515	COG1082	Xylose isomerase domain protein TIM barrel
ACPOL_3520	COG1566	PFAM secretion protein HlyD family protein
ACPOL_3527	COG1653	transport
ACPOL_3528	COG4585	Histidine kinase
ACPOL_3529	COG2197	response regulator
ACPOL_3531	COG3604	Transcriptional regulator
ACPOL_3535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACPOL_3541	COG1414	Transcriptional regulator
ACPOL_3544	COG0728	peptidoglycan biosynthetic process
ACPOL_3547	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACPOL_3552	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACPOL_3553	COG0237	dephospho-CoA kinase activity
ACPOL_3557	COG1570	exodeoxyribonuclease VII activity
ACPOL_3558	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACPOL_3570	COG0557	exoribonuclease II activity
ACPOL_3573	COG0539	negative regulation of cytoplasmic translation
ACPOL_3576	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACPOL_3577	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACPOL_3578	COG1538	Outer membrane efflux protein
ACPOL_3579	COG2132	Multicopper oxidase
ACPOL_3581	COG2814	Major facilitator Superfamily
ACPOL_3582	COG1940	carbohydrate kinase activity
ACPOL_3585	COG3706	GGDEF domain
ACPOL_3585	COG2203	Gaf domain
ACPOL_3585	COG5001	Diguanylate cyclase
ACPOL_3585	COG4251	negative regulation of phosphorylation
ACPOL_3588	COG0515	serine threonine protein kinase
ACPOL_3588	COG2815	serine threonine protein kinase
ACPOL_3590	COG1360	Flagellar Motor Protein
ACPOL_3591	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACPOL_3596	COG1012	belongs to the aldehyde dehydrogenase family
ACPOL_3597	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACPOL_3598	COG0617	tRNA 3'-terminal CCA addition
ACPOL_3599	COG2081	HI0933 family
ACPOL_3601	COG0643	Histidine kinase
ACPOL_3601	COG2198	Histidine kinase
ACPOL_3602	COG0835	chemotaxis
ACPOL_3606	COG2201	protein-glutamate methylesterase activity
ACPOL_3607	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACPOL_3609	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACPOL_3610	COG0045	succinate-CoA ligase (ADP-forming) activity
ACPOL_3611	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACPOL_3615	COG1994	Peptidase M50
ACPOL_3616	COG0180	Tryptophanyl-tRNA synthetase
ACPOL_3618	COG2814	Major facilitator Superfamily
ACPOL_3623	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACPOL_3625	COG1309	transcriptional regulator
ACPOL_3628	COG1136	(ABC) transporter
ACPOL_3633	COG0506	proline dehydrogenase activity
ACPOL_3648	COG0489	protein tyrosine kinase activity
ACPOL_3660	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ACPOL_3666	COG2132	Multicopper oxidase
ACPOL_3668	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACPOL_3669	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACPOL_3673	COG1012	belongs to the aldehyde dehydrogenase family
ACPOL_3678	COG1297	OPT oligopeptide transporter protein
ACPOL_3681	COG1957	nucleoside hydrolase
ACPOL_3684	COG5265	(ABC) transporter
ACPOL_3689	COG4585	Histidine kinase
ACPOL_3690	COG2197	response regulator
ACPOL_3692	COG3940	Belongs to the glycosyl hydrolase 43 family
ACPOL_3697	COG3234	Protein of unknown function (DUF1175)
ACPOL_3698	COG2373	Large extracellular alpha-helical protein
ACPOL_3701	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3706	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3709	COG1309	transcriptional regulator
ACPOL_3710	COG0251	oxidation-reduction process
ACPOL_3721	COG4221	oxidoreductase activity
ACPOL_3741	COG2851	Citrate transporter
ACPOL_3742	COG0583	DNA-binding transcription factor activity
ACPOL_3744	COG2258	MOSC domain
ACPOL_3747	COG0583	DNA-binding transcription factor activity
ACPOL_3749	COG1032	radical SAM domain protein
ACPOL_3750	COG1032	radical SAM domain protein
ACPOL_3756	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACPOL_3763	COG0183	Belongs to the thiolase family
ACPOL_3766	COG1621	beta-fructofuranosidase activity
ACPOL_3780	COG3842	ATPase activity
ACPOL_3781	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACPOL_3782	COG1177	transmembrane transport
ACPOL_3783	COG1231	oxidoreductase activity
ACPOL_3784	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ACPOL_3786	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACPOL_3790	COG0358	DNA primase activity
ACPOL_3791	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACPOL_3792	COG0583	DNA-binding transcription factor activity
ACPOL_3793	COG0456	acetyltransferase
ACPOL_3798	COG0187	DNA topoisomerase II activity
ACPOL_3801	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACPOL_3802	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACPOL_3803	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACPOL_3805	COG0105	UTP biosynthetic process
ACPOL_3806	COG0667	Aldo Keto reductase
ACPOL_3809	COG0745	RESPONSE REGULATOR receiver
ACPOL_3820	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3822	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACPOL_3825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACPOL_3831	COG0081	regulation of translation
ACPOL_3832	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACPOL_3833	COG0222	ribosome binding
ACPOL_3835	COG0085	RNA polymerase activity
ACPOL_3836	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACPOL_3838	COG2442	InterPro IPR007367
ACPOL_3845	COG0577	efflux transmembrane transporter activity
ACPOL_3847	COG0667	Aldo Keto reductase
ACPOL_3849	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACPOL_3851	COG3250	beta-galactosidase activity
ACPOL_3854	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3855	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3857	COG0528	UMP kinase activity
ACPOL_3859	COG0386	Belongs to the glutathione peroxidase family
ACPOL_3872	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACPOL_3873	COG0052	Belongs to the universal ribosomal protein uS2 family
ACPOL_3874	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACPOL_3875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACPOL_3877	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACPOL_3878	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACPOL_3883	COG2814	Major facilitator Superfamily
ACPOL_3893	COG1792	Involved in formation and maintenance of cell shape
ACPOL_3895	COG0768	penicillin binding
ACPOL_3896	COG0772	Belongs to the SEDS family
ACPOL_3897	COG1530	ribonuclease E activity
ACPOL_3897	COG1530	ribonuclease E activity
ACPOL_3900	COG0006	proline dipeptidase activity
ACPOL_3902	COG4106	trans-aconitate 2-methyltransferase activity
ACPOL_3906	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACPOL_3907	COG0456	acetyltransferase
ACPOL_3913	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACPOL_3917	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACPOL_3921	COG1446	asparaginase
ACPOL_3922	COG0424	maF-like protein
ACPOL_3925	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ACPOL_3928	COG0537	adenosine 5'-monophosphoramidase activity
ACPOL_3932	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACPOL_3933	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACPOL_3934	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ACPOL_3937	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACPOL_3939	COG0215	cysteine-tRNA ligase activity
ACPOL_3940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACPOL_3946	COG2318	DinB family
ACPOL_3949	COG0312	modulator of DNA gyrase
ACPOL_3957	COG1136	(ABC) transporter
ACPOL_3957	COG0577	efflux transmembrane transporter activity
ACPOL_3958	COG0028	Belongs to the TPP enzyme family
ACPOL_3959	COG0477	Major facilitator Superfamily
ACPOL_3966	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACPOL_3968	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACPOL_3969	COG0740	serine-type endopeptidase activity
ACPOL_3970	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACPOL_3971	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACPOL_3975	COG1063	alcohol dehydrogenase
ACPOL_3976	COG0738	Major facilitator superfamily
ACPOL_3977	COG4948	Mandelate Racemase Muconate Lactonizing
ACPOL_3981	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACPOL_3982	COG0367	asparagine synthase
ACPOL_3990	COG1562	ergosterol biosynthetic process
ACPOL_3991	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3992	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3998	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_3999	COG1309	transcriptional regulator
ACPOL_4004	COG2010	Cytochrome c
ACPOL_4012	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACPOL_4015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACPOL_4019	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACPOL_4019	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACPOL_4024	COG1609	Transcriptional regulator
ACPOL_4027	COG1472	Belongs to the glycosyl hydrolase 3 family
ACPOL_4028	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_4033	COG1063	alcohol dehydrogenase
ACPOL_4034	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_4036	COG3534	alpha-L-arabinofuranosidase
ACPOL_4039	COG0667	Aldo Keto reductase
ACPOL_4041	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACPOL_4043	COG0735	belongs to the Fur family
ACPOL_4051	COG3850	Histidine kinase
ACPOL_4051	COG0642	Histidine kinase
ACPOL_4053	COG1082	Xylose isomerase domain protein TIM barrel
ACPOL_4056	COG1609	Transcriptional regulator
ACPOL_4057	COG0596	Alpha beta hydrolase
ACPOL_4060	COG1725	Transcriptional regulator
ACPOL_4076	COG2801	Transposase and inactivated derivatives
ACPOL_4077	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_4080	COG2815	serine threonine protein kinase
ACPOL_4080	COG0515	serine threonine protein kinase
ACPOL_4082	COG0631	protein serine/threonine phosphatase activity
ACPOL_4097	COG3501	Rhs element vgr protein
ACPOL_4101	COG2140	Oxalate decarboxylase
ACPOL_4106	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACPOL_4107	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACPOL_4111	COG1506	peptidase
ACPOL_4111	COG0823	Involved in the tonB-independent uptake of proteins
ACPOL_4115	COG0673	inositol 2-dehydrogenase activity
ACPOL_4124	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ACPOL_4126	COG0022	dehydrogenase e1 component
ACPOL_4132	COG2211	Major facilitator Superfamily
ACPOL_4133	COG0322	excinuclease ABC activity
ACPOL_4135	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACPOL_4137	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACPOL_4141	COG0778	Nitroreductase
ACPOL_4145	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACPOL_4146	COG0438	transferase activity, transferring glycosyl groups
ACPOL_4149	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACPOL_4149	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACPOL_4150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACPOL_4152	COG0859	PFAM glycosyl transferase family 9
ACPOL_4162	COG0488	(ABC) transporter
ACPOL_4166	COG0488	(ABC) transporter
ACPOL_4168	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACPOL_4171	COG3622	Belongs to the hyi family
ACPOL_4172	COG2226	methyltransferase
ACPOL_4173	COG3685	Protein conserved in bacteria
ACPOL_4174	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACPOL_4175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACPOL_4176	COG0772	Belongs to the SEDS family
ACPOL_4177	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACPOL_4180	COG0504	CTP synthase activity
ACPOL_4189	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACPOL_4190	COG1254	Belongs to the acylphosphatase family
ACPOL_4192	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACPOL_4194	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACPOL_4195	COG0406	alpha-ribazole phosphatase activity
ACPOL_4196	COG0058	SHG alpha-glucan phosphorylase activity
ACPOL_4206	COG2135	peptidase activity
ACPOL_4207	COG0583	DNA-binding transcription factor activity
ACPOL_4209	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACPOL_4211	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACPOL_4213	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACPOL_4215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACPOL_4228	COG4977	sequence-specific DNA binding
ACPOL_4238	COG0667	Aldo Keto reductase
ACPOL_4244	COG0784	Response regulator, receiver
ACPOL_4244	COG2205	protein histidine kinase activity
ACPOL_4244	COG5002	protein histidine kinase activity
ACPOL_4248	COG0535	radical SAM domain protein
ACPOL_4260	COG1846	Transcriptional regulator
ACPOL_4261	COG0702	epimerase
ACPOL_4266	COG4221	oxidoreductase activity
ACPOL_4269	COG2226	methyltransferase
ACPOL_4270	COG0477	Major facilitator Superfamily
ACPOL_4273	COG0028	Belongs to the TPP enzyme family
ACPOL_4277	COG0154	amidase activity
ACPOL_4278	COG0154	amidase activity
ACPOL_4282	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACPOL_4291	COG0667	Aldo Keto reductase
ACPOL_4295	COG0113	porphobilinogen synthase activity
ACPOL_4296	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACPOL_4297	COG1598	PFAM Uncharacterised protein family UPF0150
ACPOL_4298	COG0321	lipoyl(octanoyl) transferase activity
ACPOL_4299	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACPOL_4300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACPOL_4301	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACPOL_4326	COG2208	phosphoserine phosphatase activity
ACPOL_4326	COG2770	Histidine kinase
ACPOL_4329	COG1611	Belongs to the LOG family
ACPOL_4338	COG5002	protein histidine kinase activity
ACPOL_4339	COG0745	RESPONSE REGULATOR receiver
ACPOL_4340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACPOL_4351	COG3710	Transcriptional regulator
ACPOL_4353	COG2267	carboxylic ester hydrolase activity
ACPOL_4357	COG0247	lactate metabolic process
ACPOL_4364	COG2169	Transcriptional regulator
ACPOL_4366	COG2197	response regulator
ACPOL_4367	COG4585	Histidine kinase
ACPOL_4369	COG3250	beta-galactosidase activity
ACPOL_4373	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACPOL_4375	COG0583	DNA-binding transcription factor activity
ACPOL_4378	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACPOL_4385	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACPOL_4386	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACPOL_4386	COG2199	diguanylate cyclase activity
ACPOL_4387	COG1595	DNA-templated transcription, initiation
ACPOL_4392	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACPOL_4394	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACPOL_4395	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACPOL_4396	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACPOL_4397	COG0509	glycine decarboxylation via glycine cleavage system
ACPOL_4398	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACPOL_4400	COG0739	heme binding
ACPOL_4410	COG3206	protein involved in exopolysaccharide biosynthesis
ACPOL_4410	COG0489	protein tyrosine kinase activity
ACPOL_4412	COG0438	transferase activity, transferring glycosyl groups
ACPOL_4421	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACPOL_4424	COG2095	MarC family integral membrane protein
ACPOL_4427	COG0739	heme binding
ACPOL_4432	COG1309	transcriptional regulator
ACPOL_4433	COG2814	Major facilitator Superfamily
ACPOL_4435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACPOL_4435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACPOL_4436	COG0552	protein localization to endoplasmic reticulum
ACPOL_4438	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACPOL_4439	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACPOL_4445	COG1597	lipid kinase activity
ACPOL_4458	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACPOL_4459	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACPOL_4460	COG1187	pseudouridine synthase activity
ACPOL_4461	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACPOL_4462	COG0306	phosphate transporter
ACPOL_4471	COG0758	DNA mediated transformation
ACPOL_4473	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACPOL_4477	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACPOL_4481	COG0583	DNA-binding transcription factor activity
ACPOL_4485	COG2080	2 iron, 2 sulfur cluster binding
ACPOL_4486	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACPOL_4487	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACPOL_4491	COG1733	regulation of RNA biosynthetic process
ACPOL_4492	COG0702	epimerase
ACPOL_4495	COG3852	Histidine kinase
ACPOL_4498	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_4499	COG1309	transcriptional regulator
ACPOL_4502	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_4504	COG0300	oxidoreductase activity
ACPOL_4506	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_4507	COG2207	Transcriptional regulator
ACPOL_4516	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_4517	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_4518	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_4520	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ACPOL_4529	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACPOL_4530	COG1127	ABC transporter
ACPOL_4558	COG0629	single-stranded DNA binding
ACPOL_4559	COG4962	Type ii secretion system protein e
ACPOL_4573	COG4221	oxidoreductase activity
ACPOL_4574	COG1063	alcohol dehydrogenase
ACPOL_4576	COG0582	viral genome integration into host DNA
ACPOL_4578	COG0583	DNA-binding transcription factor activity
ACPOL_4580	COG4585	Histidine kinase
ACPOL_4584	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_4586	COG3548	integral membrane protein
ACPOL_4591	COG2814	Major facilitator Superfamily
ACPOL_4594	COG2226	methyltransferase
ACPOL_4607	COG2814	Major facilitator Superfamily
ACPOL_4612	COG3345	alpha-galactosidase
ACPOL_4614	COG2207	Transcriptional regulator
ACPOL_4615	COG1082	Xylose isomerase domain protein TIM barrel
ACPOL_4618	COG2084	Dehydrogenase
ACPOL_4622	COG3537	Alpha-1,2-mannosidase
ACPOL_4630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACPOL_4654	COG3537	Alpha-1,2-mannosidase
ACPOL_4667	COG1064	alcohol dehydrogenase
ACPOL_4671	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACPOL_4673	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACPOL_4675	COG3345	alpha-galactosidase
ACPOL_4677	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACPOL_4681	COG4585	Histidine kinase
ACPOL_4689	COG2801	Transposase and inactivated derivatives
ACPOL_4694	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
ACPOL_4703	COG4962	Type ii secretion system protein e
ACPOL_4721	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACPOL_4722	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACPOL_4723	COG1120	ATPase activity
ACPOL_4728	COG1280	lysine exporter protein (LysE YggA)
ACPOL_4745	COG1309	transcriptional regulator
ACPOL_4759	COG0306	phosphate transporter
ACPOL_4761	COG3237	CsbD-like
ACPOL_4778	COG1335	isochorismatase
ACPOL_4791	COG1921	L-seryl-tRNASec selenium transferase activity
ACPOL_4792	COG0709	Synthesizes selenophosphate from selenide and ATP
ACPOL_4795	COG0629	single-stranded DNA binding
ACPOL_4800	COG0596	Alpha beta hydrolase
ACPOL_4802	COG0753	catalase activity
ACPOL_4810	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_4811	COG2801	Transposase and inactivated derivatives
ACPOL_4818	COG0584	glycerophosphoryl diester phosphodiesterase
ACPOL_4822	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACPOL_4829	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACPOL_4830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACPOL_4830	COG2169	Transcriptional regulator
ACPOL_4840	COG3420	alginic acid biosynthetic process
ACPOL_4844	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_4846	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_4847	COG2267	carboxylic ester hydrolase activity
ACPOL_4851	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACPOL_4856	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACPOL_4859	COG3391	amine dehydrogenase activity
ACPOL_4861	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ACPOL_4865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACPOL_4870	COG0322	excinuclease ABC activity
ACPOL_4871	COG0312	modulator of DNA gyrase
ACPOL_4874	COG3619	membrane
ACPOL_4875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACPOL_4876	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACPOL_4885	COG0673	inositol 2-dehydrogenase activity
ACPOL_4886	COG0517	IMP dehydrogenase activity
ACPOL_4886	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACPOL_4892	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ACPOL_4896	COG1846	Transcriptional regulator
ACPOL_4896	COG1940	carbohydrate kinase activity
ACPOL_4897	COG3250	beta-galactosidase activity
ACPOL_4898	COG0531	amino acid
ACPOL_4901	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ACPOL_4904	COG1160	GTP binding
ACPOL_4906	COG1199	ATP-dependent helicase activity
ACPOL_4908	COG0450	alkyl hydroperoxide reductase
ACPOL_4911	COG1506	peptidase
ACPOL_4911	COG0823	Involved in the tonB-independent uptake of proteins
ACPOL_4911	COG4946	Tricorn protease homolog
ACPOL_4914	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACPOL_4915	COG0049	tRNA binding
ACPOL_4916	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACPOL_4917	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACPOL_4919	COG0051	transcription antitermination factor activity, RNA binding
ACPOL_4920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACPOL_4921	COG0088	Forms part of the polypeptide exit tunnel
ACPOL_4922	COG0089	rRNA binding
ACPOL_4923	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACPOL_4924	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACPOL_4925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACPOL_4926	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACPOL_4927	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACPOL_4928	COG0255	Belongs to the universal ribosomal protein uL29 family
ACPOL_4929	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACPOL_4930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACPOL_4931	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACPOL_4932	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACPOL_4933	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACPOL_4934	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACPOL_4935	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACPOL_4936	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACPOL_4937	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACPOL_4938	COG1841	ribosomal large subunit assembly
ACPOL_4939	COG0200	Binds to the 23S rRNA
ACPOL_4940	COG0201	protein transport
ACPOL_4941	COG0563	adenylate kinase activity
ACPOL_4943	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACPOL_4944	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACPOL_4945	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACPOL_4946	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACPOL_4948	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACPOL_4949	COG0202	RNA polymerase activity
ACPOL_4950	COG0203	ribosomal protein L17
ACPOL_4951	COG2770	Histidine kinase
ACPOL_4951	COG2208	phosphoserine phosphatase activity
ACPOL_4953	COG0517	IMP dehydrogenase activity
ACPOL_4953	COG0516	GMP reductase activity
ACPOL_4954	COG0779	Required for maturation of 30S ribosomal subunits
ACPOL_4955	COG0195	Participates in both transcription termination and antitermination
ACPOL_4956	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACPOL_4958	COG0577	efflux transmembrane transporter activity
ACPOL_4958	COG1136	(ABC) transporter
ACPOL_4959	COG1136	(ABC) transporter
ACPOL_4959	COG0577	efflux transmembrane transporter activity
ACPOL_4961	COG1136	(ABC) transporter
ACPOL_4961	COG0577	efflux transmembrane transporter activity
ACPOL_4963	COG2204	response regulator
ACPOL_4964	COG4191	Histidine kinase
ACPOL_4972	COG0823	Involved in the tonB-independent uptake of proteins
ACPOL_4974	COG2022	thiamine diphosphate biosynthetic process
ACPOL_4975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ACPOL_4978	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACPOL_4979	COG0297	glycogen (starch) synthase activity
ACPOL_4982	COG0531	amino acid
ACPOL_4985	COG0673	inositol 2-dehydrogenase activity
ACPOL_4986	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACPOL_4991	COG0577	efflux transmembrane transporter activity
ACPOL_4991	COG1136	(ABC) transporter
ACPOL_4994	COG2895	sulfate adenylyltransferase (ATP) activity
ACPOL_4995	COG0175	sulfate reduction
ACPOL_4999	COG0346	lactoylglutathione lyase activity
ACPOL_5000	COG1012	belongs to the aldehyde dehydrogenase family
ACPOL_5002	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACPOL_5004	COG4302	ethanolamine ammonia-lyase activity
ACPOL_5005	COG4303	Ethanolamine ammonia lyase large subunit
ACPOL_5007	COG1131	(ABC) transporter
ACPOL_5016	COG0745	RESPONSE REGULATOR receiver
ACPOL_5017	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACPOL_5022	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACPOL_5026	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACPOL_5027	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACPOL_5031	COG0305	Participates in initiation and elongation during chromosome replication
ACPOL_5035	COG0445	tRNA wobble uridine modification
ACPOL_5036	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACPOL_5038	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACPOL_5040	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ACPOL_5043	COG0072	phenylalanine-tRNA ligase activity
ACPOL_5045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACPOL_5056	COG2875	Belongs to the precorrin methyltransferase family
ACPOL_5067	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACPOL_5068	COG0335	large ribosomal subunit rRNA binding
ACPOL_5069	COG0336	Belongs to the RNA methyltransferase TrmD family
ACPOL_5070	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACPOL_5071	COG1837	Belongs to the UPF0109 family
ACPOL_5072	COG0228	four-way junction DNA binding
ACPOL_5073	COG0339	signal peptide processing
ACPOL_5076	COG2382	esterase
ACPOL_5080	COG0493	'glutamate synthase
ACPOL_5080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACPOL_5082	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACPOL_5083	COG1953	Uracil, thiamine, allantoin
ACPOL_5084	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACPOL_5099	COG0248	Ppx GppA phosphatase
ACPOL_5108	COG1566	PFAM secretion protein HlyD family protein
ACPOL_5109	COG0783	Belongs to the Dps family
ACPOL_5111	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACPOL_5112	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ACPOL_5116	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACPOL_5117	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACPOL_5118	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACPOL_5121	COG1253	flavin adenine dinucleotide binding
ACPOL_5133	COG2885	chlorophyll binding
ACPOL_5143	COG1960	acyl-CoA dehydrogenase activity
ACPOL_5144	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACPOL_5145	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACPOL_5146	COG1492	cobalamin metabolic process
ACPOL_5147	COG0778	Nitroreductase
ACPOL_5151	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ACPOL_5152	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACPOL_5159	COG1349	DNA-binding transcription factor activity
ACPOL_5160	COG0494	nUDIX hydrolase
ACPOL_5162	COG4948	Mandelate Racemase Muconate Lactonizing
ACPOL_5166	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ACPOL_5167	COG3347	Dehydrogenase
ACPOL_5167	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_5168	COG1070	Carbohydrate kinase
ACPOL_5175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACPOL_5178	COG0101	tRNA pseudouridine synthase activity
ACPOL_5180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACPOL_5181	COG1956	GAF domain-containing protein
ACPOL_5182	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ACPOL_5186	COG3548	integral membrane protein
ACPOL_5188	COG0006	proline dipeptidase activity
ACPOL_5196	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACPOL_5197	COG3254	rhamnose metabolic process
ACPOL_5199	COG1904	glucuronate isomerase
ACPOL_5204	COG0346	lactoylglutathione lyase activity
ACPOL_5211	COG1366	Belongs to the anti-sigma-factor antagonist family
ACPOL_5212	COG1366	Belongs to the anti-sigma-factor antagonist family
ACPOL_5216	COG4191	Histidine kinase
ACPOL_5220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACPOL_5222	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACPOL_5228	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACPOL_5232	COG1704	LemA family
ACPOL_5235	COG1959	2 iron, 2 sulfur cluster binding
ACPOL_5236	COG1692	metallophosphoesterase
ACPOL_5238	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACPOL_5240	COG1228	amidohydrolase
ACPOL_5243	COG0356	it plays a direct role in the translocation of protons across the membrane
ACPOL_5244	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACPOL_5252	COG0138	bifunctional purine biosynthesis protein purh
ACPOL_5254	COG0513	Belongs to the DEAD box helicase family
ACPOL_5264	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACPOL_5265	COG2204	response regulator
ACPOL_5266	COG0501	Belongs to the peptidase M48B family
ACPOL_5267	COG1136	(ABC) transporter
ACPOL_5280	COG2197	response regulator
ACPOL_5282	COG4566	intracellular signal transduction
ACPOL_5283	COG4191	Histidine kinase
ACPOL_5294	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACPOL_5294	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACPOL_5295	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_5297	COG0656	L-ascorbic acid biosynthetic process
ACPOL_5300	COG2084	Dehydrogenase
ACPOL_5305	COG4566	intracellular signal transduction
ACPOL_5306	COG2318	DinB family
ACPOL_5308	COG2172	sigma factor antagonist activity
ACPOL_5310	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACPOL_5311	COG1127	ABC transporter
ACPOL_5315	COG5002	protein histidine kinase activity
ACPOL_5315	COG0784	Response regulator, receiver
ACPOL_5315	COG2205	protein histidine kinase activity
ACPOL_5319	COG0463	Glycosyl transferase, family 2
ACPOL_5322	COG1620	l-lactate permease
ACPOL_5323	COG2755	lipolytic protein G-D-S-L family
ACPOL_5323	COG0657	acetylesterase activity
ACPOL_5325	COG2205	protein histidine kinase activity
ACPOL_5326	COG2205	protein histidine kinase activity
ACPOL_5332	COG0745	RESPONSE REGULATOR receiver
ACPOL_5342	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACPOL_5343	COG0698	ribose 5-phosphate isomerase
ACPOL_5347	COG0363	glucosamine-6-phosphate deaminase activity
ACPOL_5348	COG0837	glucose binding
ACPOL_5353	COG0067	glutamate synthase
ACPOL_5353	COG0069	glutamate synthase activity
ACPOL_5353	COG0070	glutamate synthase
ACPOL_5355	COG3546	catalase activity
ACPOL_5365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACPOL_5366	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACPOL_5368	COG0514	ATP-dependent DNA helicase (RecQ)
ACPOL_5370	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_5375	COG0284	orotidine-5'-phosphate decarboxylase activity
ACPOL_5377	COG0351	phosphomethylpyrimidine kinase
ACPOL_5382	COG1131	(ABC) transporter
ACPOL_5385	COG1335	isochorismatase
ACPOL_5388	COG1349	DNA-binding transcription factor activity
ACPOL_5389	COG3142	Participates in the control of copper homeostasis
ACPOL_5391	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACPOL_5393	COG0295	cytidine deaminase activity
ACPOL_5395	COG0037	tRNA processing
ACPOL_5401	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACPOL_5402	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACPOL_5404	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACPOL_5409	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACPOL_5413	COG0442	prolyl-tRNA aminoacylation
ACPOL_5415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACPOL_5417	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACPOL_5418	COG0693	protein deglycase activity
ACPOL_5420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACPOL_5422	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACPOL_5426	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACPOL_5428	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACPOL_5429	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACPOL_5431	COG0535	radical SAM domain protein
ACPOL_5433	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
ACPOL_5434	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACPOL_5439	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACPOL_5441	COG0617	tRNA 3'-terminal CCA addition
ACPOL_5455	COG1116	anion transmembrane transporter activity
ACPOL_5457	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACPOL_5458	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACPOL_5465	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACPOL_5466	COG3956	TIGRFAM MazG family protein
ACPOL_5468	COG4948	Mandelate Racemase Muconate Lactonizing
ACPOL_5482	COG1819	glycosyl
ACPOL_5485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACPOL_5486	COG0795	lipopolysaccharide-transporting ATPase activity
ACPOL_5487	COG1937	Protein conserved in bacteria
ACPOL_5488	COG2217	Heavy metal translocating P-type atpase
ACPOL_5490	COG0745	RESPONSE REGULATOR receiver
ACPOL_5491	COG5002	protein histidine kinase activity
ACPOL_5492	COG0598	Magnesium transport protein CorA
ACPOL_5493	COG1842	Phage shock protein A
ACPOL_5495	COG2268	Band 7 protein
ACPOL_5502	COG0745	RESPONSE REGULATOR receiver
ACPOL_5502	COG3706	GGDEF domain
ACPOL_5503	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ACPOL_5504	COG1506	peptidase
ACPOL_5504	COG0823	Involved in the tonB-independent uptake of proteins
ACPOL_5506	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACPOL_5509	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACPOL_5510	COG0612	Peptidase, M16
ACPOL_5518	COG2124	cytochrome p450
ACPOL_5523	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACPOL_5524	COG0745	RESPONSE REGULATOR receiver
ACPOL_5528	COG2124	cytochrome p450
ACPOL_5529	COG3474	cytochrome
ACPOL_5539	COG4644	lycopene metabolic process
ACPOL_5562	COG2304	oxidoreductase activity
ACPOL_5575	COG1214	PFAM Peptidase M22, glycoprotease
ACPOL_5576	COG0456	acetyltransferase
ACPOL_5578	COG0688	phosphatidylethanolamine metabolic process
ACPOL_5579	COG1183	phosphatidylcholine synthase activity
ACPOL_5582	COG0457	Tetratricopeptide repeat
ACPOL_5583	COG1360	Flagellar Motor Protein
ACPOL_5584	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACPOL_5586	COG3510	cephalosporin hydroxylase
ACPOL_5588	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACPOL_5592	COG1132	(ABC) transporter
ACPOL_5596	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACPOL_5599	COG0165	Argininosuccinate lyase
ACPOL_5600	COG0137	argininosuccinate synthase activity
ACPOL_5601	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACPOL_5602	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACPOL_5603	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACPOL_5604	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACPOL_5605	COG1438	arginine binding
ACPOL_5607	COG0439	Biotin carboxylase
ACPOL_5608	COG0511	ligase activity, forming carbon-carbon bonds
ACPOL_5609	COG0006	proline dipeptidase activity
ACPOL_5611	COG0205	6-phosphofructokinase activity
ACPOL_5612	COG1022	Amp-dependent synthetase and ligase
ACPOL_5614	COG0352	thiamine-phosphate diphosphorylase activity
ACPOL_5615	COG0531	amino acid
ACPOL_5616	COG0531	amino acid
ACPOL_5619	COG1215	transferase activity, transferring glycosyl groups
ACPOL_5622	COG0302	gtp cyclohydrolase
ACPOL_5623	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACPOL_5625	COG4181	ATPase activity
ACPOL_5626	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACPOL_5628	COG0277	FAD linked oxidase domain protein
ACPOL_5629	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACPOL_5630	COG0459	protein refolding
ACPOL_5634	COG1606	tRNA processing
ACPOL_5636	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ACPOL_5637	COG1691	(AIR) carboxylase
ACPOL_5641	COG0656	L-ascorbic acid biosynthetic process
ACPOL_5642	COG0667	Aldo Keto reductase
ACPOL_5643	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_5644	COG2271	Major facilitator Superfamily
ACPOL_5651	COG1233	COG1233 Phytoene dehydrogenase and related
ACPOL_5652	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACPOL_5653	COG0156	8-amino-7-oxononanoate synthase activity
ACPOL_5654	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACPOL_5655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACPOL_5656	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACPOL_5660	COG0534	Mate efflux family protein
ACPOL_5664	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACPOL_5665	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACPOL_5666	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACPOL_5668	COG3706	GGDEF domain
ACPOL_5668	COG0745	RESPONSE REGULATOR receiver
ACPOL_5669	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ACPOL_5670	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ACPOL_5672	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACPOL_5677	COG3264	Mechanosensitive ion channel
ACPOL_5677	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ACPOL_5678	COG0438	transferase activity, transferring glycosyl groups
ACPOL_5679	COG0438	transferase activity, transferring glycosyl groups
ACPOL_5682	COG1216	Glycosyl transferase, family 2
ACPOL_5683	COG0489	protein tyrosine kinase activity
ACPOL_5683	COG3206	protein involved in exopolysaccharide biosynthesis
ACPOL_5686	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACPOL_5688	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACPOL_5689	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACPOL_5692	COG0366	Alpha amylase catalytic
ACPOL_5693	COG0366	Alpha amylase catalytic
ACPOL_5694	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACPOL_5712	COG0577	efflux transmembrane transporter activity
ACPOL_5712	COG1136	(ABC) transporter
ACPOL_5715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACPOL_5724	COG0316	Belongs to the HesB IscA family
ACPOL_5731	COG0297	glycogen (starch) synthase activity
ACPOL_5732	COG2223	nitrite transmembrane transporter activity
ACPOL_5734	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ACPOL_5738	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACPOL_5739	COG1085	galactose-1-phosphate uridylyltransferase
ACPOL_5741	COG0463	Glycosyl transferase, family 2
ACPOL_5743	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACPOL_5744	COG1132	(ABC) transporter
ACPOL_5746	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACPOL_5750	COG1136	(ABC) transporter
ACPOL_5750	COG0577	efflux transmembrane transporter activity
ACPOL_5751	COG0577	efflux transmembrane transporter activity
ACPOL_5751	COG1136	(ABC) transporter
ACPOL_5758	COG1408	metallophosphoesterase
ACPOL_5761	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACPOL_5766	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_5767	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_5769	COG0577	efflux transmembrane transporter activity
ACPOL_5769	COG1136	(ABC) transporter
ACPOL_5773	COG1335	isochorismatase
ACPOL_5775	COG1595	DNA-templated transcription, initiation
ACPOL_5781	COG0745	RESPONSE REGULATOR receiver
ACPOL_5789	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACPOL_5792	COG4952	isomerase
ACPOL_5793	COG0673	inositol 2-dehydrogenase activity
ACPOL_5797	COG0586	Pfam SNARE associated Golgi protein
ACPOL_5798	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACPOL_5800	COG1587	Uroporphyrinogen-III synthase
ACPOL_5801	COG0181	hydroxymethylbilane synthase activity
ACPOL_5802	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACPOL_5805	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACPOL_5806	COG1472	Belongs to the glycosyl hydrolase 3 family
ACPOL_5808	COG0747	negative chemotaxis
ACPOL_5809	COG2815	serine threonine protein kinase
ACPOL_5809	COG0515	serine threonine protein kinase
ACPOL_5812	COG1733	regulation of RNA biosynthetic process
ACPOL_5827	COG1136	(ABC) transporter
ACPOL_5828	COG0542	response to heat
ACPOL_5834	COG0356	it plays a direct role in the translocation of protons across the membrane
ACPOL_5835	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACPOL_5836	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACPOL_5837	COG0649	NAD binding
ACPOL_5844	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACPOL_5846	COG0713	ATP synthesis coupled electron transport
ACPOL_5849	COG1007	ATP synthesis coupled electron transport
ACPOL_5850	COG4941	Belongs to the sigma-70 factor family
ACPOL_5861	COG4783	chaperone-mediated protein folding
ACPOL_5863	COG1136	(ABC) transporter
ACPOL_5863	COG0577	efflux transmembrane transporter activity
ACPOL_5864	COG0443	Heat shock 70 kDa protein
ACPOL_5869	COG0667	Aldo Keto reductase
ACPOL_5870	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ACPOL_5873	COG3383	formate dehydrogenase (NAD+) activity
ACPOL_5874	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACPOL_5875	COG3259	Nickel-dependent hydrogenase
ACPOL_5877	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ACPOL_5878	COG0167	dihydroorotate dehydrogenase activity
ACPOL_5879	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACPOL_5879	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACPOL_5879	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACPOL_5879	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACPOL_5880	COG3795	YCII-related domain
ACPOL_5882	COG3795	YCII-related domain
ACPOL_5883	COG4941	Belongs to the sigma-70 factor family
ACPOL_5891	COG2723	6-phospho-beta-galactosidase activity
ACPOL_5892	COG0751	glycine-tRNA ligase activity
ACPOL_5893	COG0752	glycyl-tRNA synthetase alpha subunit
ACPOL_5896	COG1381	Involved in DNA repair and RecF pathway recombination
ACPOL_5899	COG0483	inositol monophosphate 1-phosphatase activity
ACPOL_5901	COG1543	Belongs to the glycosyl hydrolase 57 family
ACPOL_5905	COG1960	acyl-CoA dehydrogenase activity
ACPOL_5907	COG0183	Belongs to the thiolase family
ACPOL_5908	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACPOL_5908	COG1024	Enoyl-CoA hydratase
ACPOL_5910	COG0612	Peptidase, M16
ACPOL_5911	COG0612	Peptidase, M16
ACPOL_5912	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACPOL_5918	COG0556	nucleotide-excision repair
ACPOL_5919	COG2205	protein histidine kinase activity
ACPOL_5924	COG0436	Aminotransferase
ACPOL_5927	COG0673	inositol 2-dehydrogenase activity
ACPOL_5928	COG1366	Belongs to the anti-sigma-factor antagonist family
ACPOL_5930	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACPOL_5931	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACPOL_5932	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ACPOL_5937	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACPOL_5938	COG0077	Prephenate dehydratase
ACPOL_5938	COG1605	Chorismate mutase
ACPOL_5944	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACPOL_5946	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACPOL_5949	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACPOL_5951	COG0109	protoheme IX farnesyltransferase activity
ACPOL_5954	COG2322	membrane
ACPOL_5957	COG1309	transcriptional regulator
ACPOL_5970	COG0460	homoserine dehydrogenase
ACPOL_5975	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ACPOL_5976	COG0242	peptide deformylase activity
ACPOL_5978	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACPOL_5981	COG0745	RESPONSE REGULATOR receiver
ACPOL_5982	COG5002	protein histidine kinase activity
ACPOL_5995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACPOL_5997	COG2124	cytochrome p450
ACPOL_6001	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACPOL_6004	COG2814	Major facilitator Superfamily
ACPOL_6005	COG1331	Highly conserved protein containing a thioredoxin domain
ACPOL_6010	COG4456	Virulence-associated protein
ACPOL_6012	COG1957	nucleoside hydrolase
ACPOL_6013	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACPOL_6014	COG2009	succinate dehydrogenase
ACPOL_6015	COG1053	succinate dehydrogenase
ACPOL_6016	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACPOL_6021	COG0039	L-malate dehydrogenase activity
ACPOL_6022	COG0538	isocitrate dehydrogenase activity
ACPOL_6023	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ACPOL_6025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACPOL_6031	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACPOL_6032	COG0662	Cupin 2, conserved barrel domain protein
ACPOL_6032	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ACPOL_6033	COG1482	cell wall glycoprotein biosynthetic process
ACPOL_6035	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ACPOL_6036	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACPOL_6045	COG3961	Belongs to the TPP enzyme family
ACPOL_6056	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACPOL_6069	COG3411	Ferredoxin
ACPOL_6071	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACPOL_6079	COG1301	dicarboxylic acid transport
ACPOL_6081	COG0166	Belongs to the GPI family
ACPOL_6082	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACPOL_6085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACPOL_6088	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACPOL_6090	COG0525	valine-tRNA ligase activity
ACPOL_6093	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACPOL_6095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACPOL_6096	COG2333	competence protein COMEC
ACPOL_6096	COG0658	competence protein
ACPOL_6102	COG1663	tetraacyldisaccharide 4'-kinase activity
ACPOL_6103	COG1519	Transferase
ACPOL_6105	COG0602	queuosine metabolic process
ACPOL_6106	COG0720	synthase
ACPOL_6110	COG1595	DNA-templated transcription, initiation
ACPOL_6111	COG0477	Major facilitator Superfamily
ACPOL_6114	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACPOL_6115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACPOL_6116	COG1024	Enoyl-CoA hydratase
ACPOL_6119	COG0277	FAD linked oxidase domain protein
ACPOL_6119	COG0247	lactate metabolic process
ACPOL_6124	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACPOL_6125	COG0107	imidazoleglycerol-phosphate synthase activity
ACPOL_6127	COG0131	Imidazoleglycerol-phosphate dehydratase
ACPOL_6128	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACPOL_6130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACPOL_6131	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACPOL_6133	COG0792	nuclease activity
ACPOL_6134	COG2975	iron-sulfur cluster assembly
ACPOL_6136	COG0443	Heat shock 70 kDa protein
ACPOL_6137	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACPOL_6138	COG0316	Belongs to the HesB IscA family
ACPOL_6140	COG1104	cysteine desulfurase activity
ACPOL_6141	COG1959	2 iron, 2 sulfur cluster binding
ACPOL_6143	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACPOL_6147	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACPOL_6147	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACPOL_6148	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACPOL_6149	COG4974	Belongs to the 'phage' integrase family
ACPOL_6153	COG0741	lytic transglycosylase activity
ACPOL_6153	COG0739	heme binding
ACPOL_6153	COG1196	nuclear chromosome segregation
ACPOL_6160	COG0477	Major facilitator Superfamily
ACPOL_6189	COG0629	single-stranded DNA binding
ACPOL_6195	COG2267	carboxylic ester hydrolase activity
ACPOL_6220	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACPOL_6221	COG1733	regulation of RNA biosynthetic process
ACPOL_6223	COG0412	Dienelactone hydrolase
ACPOL_6224	COG4221	oxidoreductase activity
ACPOL_6232	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ACPOL_6233	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ACPOL_6247	COG0667	Aldo Keto reductase
ACPOL_6252	COG0708	Exodeoxyribonuclease III
ACPOL_6256	COG0778	Nitroreductase
ACPOL_6262	COG1228	amidohydrolase
ACPOL_6271	COG0402	S-adenosylhomocysteine deaminase activity
ACPOL_6277	COG2207	Transcriptional regulator
ACPOL_6278	COG4221	oxidoreductase activity
ACPOL_6285	COG0066	3-isopropylmalate dehydratase activity
ACPOL_6286	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACPOL_6287	COG0473	3-isopropylmalate dehydrogenase activity
ACPOL_6290	COG2311	Membrane
ACPOL_6299	COG0384	phenazine biosynthesis protein PhzF
ACPOL_6303	COG1063	alcohol dehydrogenase
ACPOL_6308	COG0745	RESPONSE REGULATOR receiver
ACPOL_6317	COG0367	asparagine synthase
ACPOL_6319	COG1505	serine-type exopeptidase activity
ACPOL_6324	COG1132	(ABC) transporter
ACPOL_6357	COG3436	PFAM IS66 Orf2 family protein
ACPOL_6359	COG0582	viral genome integration into host DNA
ACPOL_6360	COG0582	viral genome integration into host DNA
ACPOL_6361	COG0582	viral genome integration into host DNA
ACPOL_6363	COG3344	reverse transcriptase
ACPOL_6366	COG1595	DNA-templated transcription, initiation
ACPOL_6370	COG2801	Transposase and inactivated derivatives
ACPOL_6370	COG3415	Transposase
ACPOL_6373	COG0629	single-stranded DNA binding
ACPOL_6392	COG3118	belongs to the thioredoxin family
ACPOL_6394	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACPOL_6395	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACPOL_6396	COG2080	2 iron, 2 sulfur cluster binding
ACPOL_6403	COG0582	viral genome integration into host DNA
ACPOL_6404	COG4804	nuclease activity
ACPOL_6405	COG3316	Transposase and inactivated derivatives
ACPOL_6410	COG3344	reverse transcriptase
ACPOL_6429	COG0493	'glutamate synthase
ACPOL_6437	COG2197	response regulator
ACPOL_6441	COG3850	Histidine kinase
ACPOL_6446	COG0531	amino acid
ACPOL_6461	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACPOL_6464	COG1228	amidohydrolase
ACPOL_6471	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACPOL_6476	COG2207	Transcriptional regulator
ACPOL_6481	COG0531	amino acid
ACPOL_6488	COG2311	Membrane
ACPOL_6506	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACPOL_6508	COG3436	PFAM IS66 Orf2 family protein
ACPOL_6509	COG4372	Transposase
ACPOL_6511	COG5002	protein histidine kinase activity
ACPOL_6512	COG0745	RESPONSE REGULATOR receiver
ACPOL_6525	COG0667	Aldo Keto reductase
ACPOL_6550	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_6554	COG0154	amidase activity
ACPOL_6555	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_6557	COG1064	alcohol dehydrogenase
ACPOL_6560	COG1063	alcohol dehydrogenase
ACPOL_6562	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_6570	COG1275	C4-dicarboxylate transporter malic acid transport protein
ACPOL_6573	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACPOL_6575	COG2080	2 iron, 2 sulfur cluster binding
ACPOL_6576	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ACPOL_6577	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACPOL_6595	COG0604	alcohol dehydrogenase
ACPOL_6603	COG3548	integral membrane protein
ACPOL_6605	COG1275	C4-dicarboxylate transporter malic acid transport protein
ACPOL_6609	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_6620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACPOL_6620	COG2207	Transcriptional regulator
ACPOL_6622	COG4566	intracellular signal transduction
ACPOL_6628	COG1609	Transcriptional regulator
ACPOL_6637	COG1501	Belongs to the glycosyl hydrolase 31 family
ACPOL_6638	COG1501	Belongs to the glycosyl hydrolase 31 family
ACPOL_6645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACPOL_6648	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACPOL_6655	COG3186	Phenylalanine-4-hydroxylase
ACPOL_6656	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ACPOL_6658	COG0667	Aldo Keto reductase
ACPOL_6661	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACPOL_6663	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACPOL_6663	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACPOL_6664	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACPOL_6666	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACPOL_6668	COG0505	Belongs to the CarA family
ACPOL_6673	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACPOL_6676	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACPOL_6680	COG1185	polyribonucleotide nucleotidyltransferase activity
ACPOL_6681	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACPOL_6685	COG2814	Major facilitator Superfamily
ACPOL_6691	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACPOL_6694	COG1970	mechanosensitive ion channel activity
ACPOL_6696	COG1942	4-Oxalocrotonate Tautomerase
ACPOL_6698	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ACPOL_6703	COG0254	rRNA binding
ACPOL_6704	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACPOL_6707	COG3403	YqcI/YcgG family
ACPOL_6709	COG3279	Response regulator of the LytR AlgR family
ACPOL_6710	COG3275	phosphorelay sensor kinase activity
ACPOL_6712	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACPOL_6714	COG0326	Molecular chaperone. Has ATPase activity
ACPOL_6728	COG3316	Transposase and inactivated derivatives
ACPOL_6773	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ACPOL_6810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACPOL_6816	COG3316	Transposase and inactivated derivatives
ACPOL_6821	COG3064	Membrane
ACPOL_6825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACPOL_6828	COG1132	(ABC) transporter
ACPOL_6835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACPOL_6843	COG3316	Transposase and inactivated derivatives
ACPOL_6844	COG2203	Gaf domain
ACPOL_6844	COG2199	diguanylate cyclase activity
ACPOL_6864	COG0704	Plays a role in the regulation of phosphate uptake
ACPOL_6873	COG4453	Protein conserved in bacteria
ACPOL_6874	COG2205	protein histidine kinase activity
ACPOL_6876	COG2801	Transposase and inactivated derivatives
ACPOL_6877	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_6879	COG2801	Transposase and inactivated derivatives
ACPOL_6888	COG0306	phosphate transporter
ACPOL_6890	COG1923	regulation of RNA biosynthetic process
ACPOL_6896	COG0629	single-stranded DNA binding
ACPOL_6903	COG4804	nuclease activity
ACPOL_6920	COG3316	Transposase and inactivated derivatives
ACPOL_6922	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACPOL_6925	COG3316	Transposase and inactivated derivatives
ACPOL_6950	COG4644	lycopene metabolic process
ACPOL_6956	COG2199	diguanylate cyclase activity
ACPOL_6956	COG2203	Gaf domain
ACPOL_6963	COG3537	Alpha-1,2-mannosidase
ACPOL_6980	COG3706	GGDEF domain
ACPOL_6988	COG3345	alpha-galactosidase
ACPOL_6989	COG3316	Transposase and inactivated derivatives
ACPOL_7006	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_7017	COG2801	Transposase and inactivated derivatives
ACPOL_7021	COG3059	membrane
ACPOL_7022	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACPOL_7030	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_7035	COG0515	serine threonine protein kinase
ACPOL_7038	COG1506	peptidase
ACPOL_7038	COG0823	Involved in the tonB-independent uptake of proteins
ACPOL_7038	COG4946	Tricorn protease homolog
ACPOL_7071	COG1940	carbohydrate kinase activity
ACPOL_7072	COG2814	Major facilitator Superfamily
ACPOL_7073	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_7081	COG1028	Short-chain dehydrogenase reductase Sdr
ACPOL_7113	COG2267	carboxylic ester hydrolase activity
ACPOL_7114	COG1595	DNA-templated transcription, initiation
ACPOL_7130	COG4977	sequence-specific DNA binding
ACPOL_7134	COG0629	single-stranded DNA binding
ACPOL_7139	COG0628	permease
ACPOL_7149	COG0628	permease
ACPOL_7154	COG0629	single-stranded DNA binding
ACPOL_7158	COG4977	sequence-specific DNA binding
ACPOL_7179	COG0667	Aldo Keto reductase
ACPOL_7181	COG0738	Major facilitator superfamily
ACPOL_7182	COG1063	alcohol dehydrogenase
ACPOL_7187	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_7190	COG1475	DNA binding
ACPOL_7196	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_7198	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ACPOL_7200	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_7202	COG0673	inositol 2-dehydrogenase activity
ACPOL_7205	COG1902	pentaerythritol trinitrate reductase activity
ACPOL_7207	COG2197	response regulator
ACPOL_7212	COG3547	Transposase (IS116 IS110 IS902 family)
ACPOL_7240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACPOL_7244	COG2948	multi-organism process
ACPOL_7245	COG3504	Conjugal transfer protein
ACPOL_7250	COG3451	type IV secretory pathway VirB4
ACPOL_7251	COG5268	conjugation
ACPOL_7253	COG4962	Type ii secretion system protein e
ACPOL_7264	COG3316	Transposase and inactivated derivatives
ACPOL_7266	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACPOL_7268	COG3316	Transposase and inactivated derivatives