locus-tag	class	description
AFERRID_00020	ENOG4105KT5	UmuD protein
AFERRID_00030	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AFERRID_00120	ENOG4108IJF	Heavy metal efflux pump, CzcA
AFERRID_00210	ENOG4105C3J	Cysteine desulfurase
AFERRID_00530	ENOG4107RY6	amino acid
AFERRID_00540	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AFERRID_00550	ENOG4107QRI	Phosphoketolase
AFERRID_00580	ENOG4105CSR	polyphosphate kinase 2
AFERRID_00610	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AFERRID_00630	ENOG4108J5G	6-phosphogluconate dehydrogenase
AFERRID_00650	ENOG4105BZP	glycoside hydrolase 15-related
AFERRID_00680	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AFERRID_00690	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_00700	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_00710	ENOG4105GKE	subunit e
AFERRID_00720	ENOG4107QIZ	NADH dehydrogenase
AFERRID_00730	ENOG4108IEH	NADH dehydrogenase subunit g
AFERRID_00740	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AFERRID_00750	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_00760	ENOG4107UFS	subunit j
AFERRID_00770	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_00780	ENOG4105D65	subunit l
AFERRID_00790	ENOG4105C8S	subunit m
AFERRID_00800	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_00810	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AFERRID_00840	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AFERRID_00880	ENOG4105DUM	transcriptional regulator, lysR family
AFERRID_00920	ENOG4107RDB	Major Facilitator
AFERRID_01060	ENOG4105CVK	Glutamate decarboxylase
AFERRID_01070	ENOG4105E5D	amino acid
AFERRID_01080	ENOG4105E5D	amino acid
AFERRID_01110	ENOG4105H2K	paraquat-inducible protein a
AFERRID_01160	ENOG41067VN	Glutaredoxin
AFERRID_01170	ENOG4105C59	p-type ATPase
AFERRID_01320	ENOG4105XB7	anti-repressor protein
AFERRID_01520	ENOG4105M7P	phage repressor
AFERRID_01560	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AFERRID_01570	ENOG4105VTW	prevent-host-death family
AFERRID_01600	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFERRID_01610	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFERRID_01620	ENOG4105DHQ	Histidine kinase
AFERRID_01630	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AFERRID_01840	ENOG41067CW	
AFERRID_01990	ENOG4105F5W	AtP-binding protein
AFERRID_02000	ENOG4106IJN	integrase catalytic domain-containing protein
AFERRID_02010	ENOG41082AG	Plasmid maintenance system antidote protein
AFERRID_02030	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AFERRID_02040	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AFERRID_02050	ENOG4105VIE	preprotein translocase, subunit YajC
AFERRID_02060	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AFERRID_02070	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AFERRID_02080	ENOG4105C37	(CBS) domain
AFERRID_02100	ENOG4105C28	cystathionine
AFERRID_02110	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AFERRID_02130	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AFERRID_02140	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AFERRID_02150	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AFERRID_02160	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AFERRID_02170	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AFERRID_02180	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AFERRID_02200	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AFERRID_02210	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AFERRID_02220	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AFERRID_02230	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
AFERRID_02240	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AFERRID_02250	ENOG4105N82	Endonuclease
AFERRID_02260	ENOG4105D07	Signal peptide peptidase, SppA
AFERRID_02320	ENOG4105D0M	Protease HtpX homolog
AFERRID_02330	ENOG4105D0M	Protease HtpX homolog
AFERRID_02340	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFERRID_02410	ENOG41089UC	methyltransferase, type 11
AFERRID_02440	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AFERRID_02450	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AFERRID_02460	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AFERRID_02490	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AFERRID_02530	ENOG410901P	UPF0249 protein
AFERRID_02570	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AFERRID_02590	ENOG4105FE1	phytoene synthase
AFERRID_02600	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AFERRID_02610	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AFERRID_02620	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AFERRID_02660	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AFERRID_02700	ENOG4105D48	metallophosphoesterase
AFERRID_02710	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AFERRID_02740	ENOG4105CJN	penicillin-binding protein
AFERRID_02750	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AFERRID_02760	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AFERRID_02770	ENOG4105C3G	gtp-binding protein
AFERRID_02780	ENOG4108JCI	Transcriptional regulator
AFERRID_02830	ENOG4107TDF	Formate hydrogenlyase subunit 4
AFERRID_02850	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AFERRID_02860	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_02870	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_02890	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AFERRID_02920	ENOG4105DUM	transcriptional regulator, lysR family
AFERRID_02930	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AFERRID_02940	ENOG4107BJW	polysaccharide deacetylase
AFERRID_02960	ENOG4107QK9	Beta-lactamase
AFERRID_02970	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AFERRID_02990	ENOG4105I08	Pseudouridine synthase
AFERRID_03000	ENOG4105DWY	Agmatine deiminase
AFERRID_03010	ENOG4105DB1	molybdopterin oxidoreductase
AFERRID_03020	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AFERRID_03070	ENOG4105C4R	Atp-dependent dna helicase
AFERRID_03080	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
AFERRID_03090	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AFERRID_03100	ENOG4105E0C	molybdate abc transporter
AFERRID_03120	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AFERRID_03130	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AFERRID_03140	ENOG41087PB	Frataxin-like domain
AFERRID_03180	ENOG4108M8S	permease YjgP YjgQ family protein
AFERRID_03190	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AFERRID_03220	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AFERRID_03230	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AFERRID_03240	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AFERRID_03270	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
AFERRID_03280	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AFERRID_03300	ENOG4105KAF	membrAne
AFERRID_03340	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AFERRID_03350	ENOG4105EI2	Pseudouridine synthase
AFERRID_03360	ENOG4107QQB	Ribonuclease E
AFERRID_03370	ENOG4105C8N	cysteinyl-tRNA synthetase
AFERRID_03380	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AFERRID_03390	ENOG4108JQC	penicillin-binding protein 1A
AFERRID_03400	ENOG4108JQC	penicillin-binding protein 1A
AFERRID_03430	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
AFERRID_03440	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AFERRID_03450	ENOG4105C08	Histidine kinase
AFERRID_03460	ENOG4105C08	Histidine kinase
AFERRID_03490	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AFERRID_03500	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AFERRID_03520	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AFERRID_03530	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFERRID_03550	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AFERRID_03570	ENOG4108YZA	Nitrogen regulatory protein pii
AFERRID_03700	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AFERRID_03710	ENOG4105C12	Phosphoribosylglycinamide synthetase
AFERRID_03720	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AFERRID_03730	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AFERRID_03740	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AFERRID_03790	ENOG4105M8F	Biopolymer transport protein exbD tolR
AFERRID_03890	ENOG4105C54	Major Facilitator superfamily
AFERRID_03910	ENOG410902C	phosphohistidine phosphatase, SixA
AFERRID_03930	ENOG4105E0F	Histidine kinase
AFERRID_03940	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AFERRID_03950	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AFERRID_03960	ENOG4108M8W	Monooxygenase
AFERRID_03990	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
AFERRID_04010	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AFERRID_04020	ENOG4105CPW	cytochrome b561
AFERRID_04040	ENOG4105D94	Major Facilitator Superfamily
AFERRID_04050	ENOG4106NZI	LysR family Transcriptional regulator
AFERRID_04060	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AFERRID_04070	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AFERRID_04080	ENOG4105C98	muts2 protein
AFERRID_04100	ENOG4105VCC	30S ribosomal protein S21
AFERRID_04110	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AFERRID_04120	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AFERRID_04130	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AFERRID_04160	ENOG4105CSA	Coproporphyrinogen iii oxidase
AFERRID_04180	ENOG4108R99	pseudouridine synthase
AFERRID_04200	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFERRID_04210	ENOG4105DZ1	carboxypeptidase
AFERRID_04250	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
AFERRID_04270	ENOG4105C8V	SAICAR synthetase
AFERRID_04300	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AFERRID_04310	ENOG4108UT2	hemolysin iii
AFERRID_04320	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AFERRID_04340	ENOG4105VW4	glutaredoxin 3
AFERRID_04350	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AFERRID_04370	ENOG4105BZS	acriflavin resistance protein
AFERRID_04380	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AFERRID_04400	ENOG41080HT	Transcriptional regulator, arsr family
AFERRID_04410	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AFERRID_04440	ENOG4105CUZ	uba thif-type nad fad binding protein
AFERRID_04450	ENOG4105F8V	Hydrolase, tatD family
AFERRID_04460	ENOG4105D0A	hydroxylase
AFERRID_04470	ENOG4105D0A	hydroxylase
AFERRID_04480	ENOG4105W0Z	cytoplasmic protein
AFERRID_04490	ENOG4105C0P	Mg chelatase subunit ChlI
AFERRID_04530	ENOG41082IR	Excinuclease ABC C subunit domain protein
AFERRID_04590	ENOG4105CMR	udp-glucose 4-epimerase
AFERRID_04600	ENOG4108MX3	Polysaccharide Biosynthesis Protein
AFERRID_04630	ENOG4108KBE	Glycosyl transferase, family 2
AFERRID_04690	ENOG4105D3Q	Sugar transferase
AFERRID_04730	ENOG4105C0P	Mg chelatase subunit ChlI
AFERRID_04750	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AFERRID_04770	ENOG41072GX	Peptidase M22 Glycoprotease
AFERRID_04780	ENOG4105DVT	helicase
AFERRID_04810	ENOG4105K4H	Nlp p60 protein
AFERRID_04870	ENOG4108Z86	Glutamine amidotransferase
AFERRID_04880	ENOG4105DQR	SNARE associated Golgi
AFERRID_04910	ENOG4105DUM	transcriptional regulator, lysR family
AFERRID_04940	ENOG4105DGU	Histone deacetylase
AFERRID_04950	ENOG4105FAE	von Willebrand factor, type A
AFERRID_05040	ENOG4107QZT	geranylgeranyl reductase
AFERRID_05050	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
AFERRID_05070	ENOG4105PHD	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AFERRID_05090	ENOG4105RQ5	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AFERRID_05100	ENOG41086B8	CoB-CoM heterodisulfide reductase
AFERRID_05130	ENOG4105EWK	phytoene
AFERRID_05160	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
AFERRID_05170	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AFERRID_05180	ENOG41082J7	Rhodanese domain protein
AFERRID_05190	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AFERRID_05210	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AFERRID_05220	ENOG4105DFF	Rod shape-determining protein mreb
AFERRID_05230	ENOG4105DFF	Rod shape-determining protein mreb
AFERRID_05240	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AFERRID_05260	ENOG4105CJN	penicillin-binding protein
AFERRID_05270	ENOG4105CNI	cell division protein FtsW
AFERRID_05280	ENOG4105DZ1	carboxypeptidase
AFERRID_05300	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AFERRID_05310	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AFERRID_05410	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AFERRID_05420	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AFERRID_05440	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AFERRID_05480	ENOG4105WPN	DNA integration recombination invertion protein
AFERRID_05540	ENOG4108K3A	Glutathione S-transferase
AFERRID_05550	ENOG4105KVH	Transcriptional regulator
AFERRID_05560	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AFERRID_05570	ENOG4108JUA	Transcriptional regulator
AFERRID_05650	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AFERRID_05660	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AFERRID_05670	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AFERRID_05680	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AFERRID_05690	ENOG41082NX	50s ribosomal protein l35
AFERRID_05700	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AFERRID_05710	ENOG4105C22	threonyL-tRNA synthetase
AFERRID_05720	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_05730	ENOG4105C8S	subunit m
AFERRID_05750	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_05760	ENOG4105DF2	NADH dehydrogenase subunit j
AFERRID_05770	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_05780	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AFERRID_05800	ENOG4107QIZ	NADH dehydrogenase
AFERRID_05810	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
AFERRID_05830	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_05840	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AFERRID_05850	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFERRID_05860	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AFERRID_05880	ENOG4105CP7	Triose-phosphate isomerase
AFERRID_05890	ENOG4105CP7	Triose-phosphate isomerase
AFERRID_05900	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AFERRID_05910	ENOG4105EEI	dihydropteroate synthase
AFERRID_05920	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AFERRID_05930	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AFERRID_05940	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AFERRID_05950	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AFERRID_06130	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
AFERRID_06150	ENOG4105EQR	Transposase IS116 IS110 IS902
AFERRID_06210	ENOG4105DHP	deoxycytidine triphosphate deaminase
AFERRID_06240	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AFERRID_06250	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AFERRID_06260	ENOG4105CFG	Acts as a chaperone (By similarity)
AFERRID_06270	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AFERRID_06280	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AFERRID_06290	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AFERRID_06300	ENOG4105W0E	50S ribosomal protein L33
AFERRID_06310	ENOG4105KDC	50s ribosomal protein l28
AFERRID_06320	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AFERRID_06330	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AFERRID_06340	ENOG4105C9Q	fumarate hydratase class II
AFERRID_06350	ENOG4105DPN	Oligoendopeptidase f
AFERRID_06390	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AFERRID_06400	ENOG4105CY0	Metallo-Beta-Lactamase
AFERRID_06420	ENOG4105CSM	endonuclease III
AFERRID_06490	ENOG4108JJA	ABC, transporter
AFERRID_06510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AFERRID_06710	ENOG4107RDJ	Sulfotransferase
AFERRID_06770	ENOG4106RZ4	Peptidase U32
AFERRID_06780	ENOG4105CFP	Peptidase U32
AFERRID_06790	ENOG4105XPQ	lipid carrier protein
AFERRID_06810	ENOG41090Y2	cytochrome C
AFERRID_06820	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AFERRID_06830	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AFERRID_06840	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AFERRID_06850	ENOG4105EIX	cytochrome c1
AFERRID_06890	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AFERRID_06900	ENOG4105HBR	Rna-binding protein
AFERRID_06910	ENOG4105NWN	ApaG protein
AFERRID_06920	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AFERRID_06950	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AFERRID_06980	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AFERRID_06990	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AFERRID_07000	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AFERRID_07020	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AFERRID_07030	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AFERRID_07040	ENOG4105CAK	Cell division ATP-binding protein ftsE
AFERRID_07050	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AFERRID_07060	ENOG4106H78	methyltransferase
AFERRID_07070	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AFERRID_07080	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AFERRID_07090	ENOG410890F	Dynamin family
AFERRID_07100	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AFERRID_07110	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AFERRID_07120	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AFERRID_07130	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AFERRID_07140	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
AFERRID_07150	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AFERRID_07160	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AFERRID_07190	ENOG4105EN6	Membrane
AFERRID_07290	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AFERRID_07300	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AFERRID_07430	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AFERRID_07490	ENOG410856B	UPF0235 protein
AFERRID_07540	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AFERRID_07570	ENOG4105YES	addiction module antidote protein
AFERRID_07610	ENOG4105E2V	Glycosyltransferase 36
AFERRID_07680	ENOG4107RAQ	aminopeptidase
AFERRID_07700	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AFERRID_07710	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AFERRID_07720	ENOG4105CDU	Replicative dna helicase
AFERRID_07730	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AFERRID_07760	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AFERRID_07770	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AFERRID_07780	ENOG4105C0X	amino acid
AFERRID_07800	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AFERRID_07840	ENOG4105C6T	cysteine synthase
AFERRID_07880	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AFERRID_07890	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AFERRID_07910	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
AFERRID_07920	ENOG4105DKQ	ROK family
AFERRID_07930	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AFERRID_07940	ENOG4106BRA	Membrane
AFERRID_07960	ENOG4108UUM	single-stranded DNA-binding protein
AFERRID_07970	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AFERRID_07990	ENOG4107QR8	Thioredoxin
AFERRID_08000	ENOG4105C0H	protease
AFERRID_08010	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AFERRID_08030	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AFERRID_08040	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AFERRID_08050	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AFERRID_08060	ENOG4105K5M	30s ribosomal protein S16
AFERRID_08070	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AFERRID_08080	ENOG4105CAU	Arsenical resistance protein, ArsH
AFERRID_08110	ENOG4108UXE	Protein tyrosine phosphatase
AFERRID_08130	ENOG4105CJ1	ABC, transporter
AFERRID_08140	ENOG4107QWP	ABC-2 type transporter
AFERRID_08150	ENOG4107QWP	ABC-2 type transporter
AFERRID_08160	ENOG4107QWP	ABC-2 type transporter
AFERRID_08210	ENOG4105RQ5	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AFERRID_08270	ENOG4108ZG0	Ompa motb domain protein
AFERRID_08420	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AFERRID_08440	ENOG4105C5H	ABC transporter
AFERRID_08470	ENOG4105CJN	penicillin-binding protein
AFERRID_08490	ENOG4105EAH	synthase
AFERRID_08510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AFERRID_08520	ENOG4105CUX	Signal transduction histidine kinase
AFERRID_08570	ENOG4105CYN	Serine protein kinase
AFERRID_08580	ENOG4105BZU	Histidine kinase
AFERRID_08590	ENOG4106AKX	UPF0229 protein
AFERRID_08600	ENOG4105ED1	spovr family
AFERRID_08630	ENOG4108YZA	Nitrogen regulatory protein pii
AFERRID_08640	ENOG4105BZU	Histidine kinase
AFERRID_08700	ENOG4107SVH	Potassium channel protein
AFERRID_08710	ENOG4105DZ1	carboxypeptidase
AFERRID_08720	ENOG4105C89	phosphohexose isomerase
AFERRID_08750	ENOG4105WMR	Protein CrcB homolog
AFERRID_08780	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AFERRID_08800	ENOG4105DSY	exodeoxyribonuclease V, gamma
AFERRID_08820	ENOG4107QKA	exodeoxyribonuclease V beta
AFERRID_08830	ENOG4107QYX	exodeoxyribonuclease v alpha
AFERRID_08840	ENOG4107QYX	exodeoxyribonuclease v alpha
AFERRID_08850	ENOG4107QYX	exodeoxyribonuclease v alpha
AFERRID_08950	ENOG4105E0X	reductase
AFERRID_08960	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AFERRID_08980	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AFERRID_09000	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AFERRID_09030	ENOG4108Z03	MAF-like protein
AFERRID_09040	ENOG4105C03	ribonuclease
AFERRID_09050	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AFERRID_09070	ENOG4107WP9	Histidine kinase
AFERRID_09090	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AFERRID_09110	ENOG4107U8J	Export protein
AFERRID_09140	ENOG4105ECX	polysaccharide export
AFERRID_09150	ENOG4108RDB	capsule polysaccharide export inner-membrane protein
AFERRID_09210	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AFERRID_09300	ENOG4105EY8	ABC transporter
AFERRID_09340	ENOG4108TJN	glycosyl transferase group 1
AFERRID_09350	ENOG4105BZ1	(ABC) transporter
AFERRID_09360	ENOG41082BV	acetyltransferase
AFERRID_09410	ENOG4105C3U	ABC transporter
AFERRID_09420	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AFERRID_09480	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AFERRID_09490	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AFERRID_09520	ENOG4105E02	MotA TolQ exbB proton channel
AFERRID_09530	ENOG4105M15	transport protein ExbD
AFERRID_09590	ENOG41084CK	capsule polysaccharide
AFERRID_09620	ENOG4105CEN	a g-specific adenine glycosylase
AFERRID_09640	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AFERRID_09650	ENOG41080Z8	PHOSPHOCARRIER protein
AFERRID_09670	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AFERRID_09680	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AFERRID_09690	ENOG4105DM4	PTS System
AFERRID_09700	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AFERRID_09710	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AFERRID_09720	ENOG4108IUZ	ABC transporter
AFERRID_09730	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AFERRID_09750	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AFERRID_09760	ENOG4105C2X	Arabinose 5-phosphate isomerase
AFERRID_09790	ENOG4108S0S	Nucleotidyl transferase
AFERRID_09800	ENOG4105EHM	Aminoglycoside phosphotransferase
AFERRID_09810	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AFERRID_09820	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AFERRID_09830	ENOG4105E3A	(ABC) transporter
AFERRID_09840	ENOG4105E3A	(ABC) transporter
AFERRID_09860	ENOG4105M2J	Glutaredoxin
AFERRID_09870	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AFERRID_09880	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AFERRID_09890	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AFERRID_09900	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AFERRID_09910	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AFERRID_09920	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AFERRID_09930	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AFERRID_09940	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AFERRID_09960	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AFERRID_09970	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AFERRID_09980	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AFERRID_09990	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AFERRID_10000	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
AFERRID_10020	ENOG4105FAE	von Willebrand factor, type A
AFERRID_10030	ENOG4105K70	DNA-binding protein
AFERRID_10040	ENOG4105BZU	Histidine kinase
AFERRID_10050	ENOG4105CD3	dihydroorotase
AFERRID_10060	ENOG4105CXT	aspartate transcarbamylase
AFERRID_10070	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AFERRID_10080	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AFERRID_10100	ENOG4108UJU	UPF0301 protein
AFERRID_10110	ENOG4105D7Z	glutathione synthase
AFERRID_10130	ENOG4105BZN	citrate synthase
AFERRID_10140	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AFERRID_10150	ENOG4107QN2	dihydrolipoyl dehydrogenase
AFERRID_10200	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AFERRID_10210	ENOG4108UJD	30S ribosomal protein S9
AFERRID_10220	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AFERRID_10250	ENOG4108PXI	ErfK YbiS YcfS YnhG
AFERRID_10270	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AFERRID_10280	ENOG4105D1H	recombination factor protein RarA
AFERRID_10300	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AFERRID_10310	ENOG4105CNU	cell division protein FtsK
AFERRID_10320	ENOG4105C3M	thioredoxin reductase
AFERRID_10350	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AFERRID_10360	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AFERRID_10370	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AFERRID_10380	ENOG4108JA2	transcriptioN-repair coupling factor
AFERRID_10390	ENOG4105EAC	phosphoserine phosphatase
AFERRID_10400	ENOG4105EHV	domain protein
AFERRID_10420	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AFERRID_10430	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AFERRID_10470	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AFERRID_10490	ENOG4105W5Q	DNA repair protein (RadC
AFERRID_10510	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AFERRID_10520	ENOG4108ZT0	50S ribosomal protein l17
AFERRID_10530	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AFERRID_10540	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AFERRID_10550	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AFERRID_10560	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFERRID_10570	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AFERRID_10580	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AFERRID_10590	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AFERRID_10600	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AFERRID_10610	ENOG41084RK	50S ribosomal protein L30
AFERRID_10620	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AFERRID_10630	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AFERRID_10640	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AFERRID_10650	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AFERRID_10660	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFERRID_10670	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AFERRID_10680	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AFERRID_10690	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AFERRID_10710	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AFERRID_10720	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AFERRID_10730	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AFERRID_10740	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AFERRID_10750	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFERRID_10760	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AFERRID_10770	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AFERRID_10780	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AFERRID_10790	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AFERRID_10800	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AFERRID_10810	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AFERRID_10820	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AFERRID_10830	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AFERRID_10840	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AFERRID_10850	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AFERRID_10860	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AFERRID_10870	ENOG4108VZM	50s ribosomal protein L10
AFERRID_10880	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AFERRID_10890	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AFERRID_10900	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AFERRID_10920	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AFERRID_10940	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AFERRID_10980	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AFERRID_10990	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AFERRID_11000	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AFERRID_11020	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AFERRID_11030	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AFERRID_11040	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AFERRID_11060	ENOG4105DWV	Homoserine O-trans-acetylase
AFERRID_11070	ENOG4105DWV	Homoserine O-trans-acetylase
AFERRID_11090	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AFERRID_11100	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AFERRID_11120	ENOG4105CHH	sulfate transporter
AFERRID_11130	ENOG4105C26	Dehydrogenase
AFERRID_11180	ENOG4105DZR	Type I site-specific deoxyribonuclease
AFERRID_11190	ENOG4108UPT	UPF0178 protein
AFERRID_11200	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AFERRID_11210	ENOG4105K46	50S ribosomal protein l27
AFERRID_11220	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFERRID_11230	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AFERRID_11240	ENOG41090R7	Ferric uptake
AFERRID_11250	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AFERRID_11260	ENOG4108Z1B	Cyclase dehydrase
AFERRID_11270	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AFERRID_11280	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AFERRID_11320	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AFERRID_11330	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AFERRID_11340	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AFERRID_11350	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AFERRID_11410	ENOG4105CZX	twitching motility protein
AFERRID_11430	ENOG4105CZX	twitching motility protein
AFERRID_11440	ENOG4105CZX	twitching motility protein
AFERRID_11450	ENOG4105DFA	alanine racemase domain protein
AFERRID_11460	ENOG4105II7	pyrroline-5-carboxylate reductase
AFERRID_11470	ENOG4108VIA	integral membrane protein
AFERRID_11480	ENOG4105VZ9	UPF0235 protein
AFERRID_11490	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AFERRID_11510	ENOG4105CW7	secretion protein, HlyD family
AFERRID_11520	ENOG4105CAS	nag kinase
AFERRID_11530	ENOG4105R8C	Transcriptional regulator
AFERRID_11580	ENOG4108EX3	reductase
AFERRID_11590	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AFERRID_11600	ENOG4105C4B	ABC transporter, permease
AFERRID_11610	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AFERRID_11620	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AFERRID_11640	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AFERRID_11660	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AFERRID_11670	ENOG4105MJ2	Competence protein
AFERRID_11680	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AFERRID_11690	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
AFERRID_11700	ENOG4105C87	Aminotransferase class I and II
AFERRID_11710	ENOG4105D1S	lipid A biosynthesis
AFERRID_11720	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AFERRID_11740	ENOG4105D16	lipopolysaccharide heptosyltransferase i
AFERRID_11750	ENOG4106WTF	Glycosyl transferase, family 2
AFERRID_11800	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AFERRID_11810	ENOG4107T94	Endo-14-beta-xylanase
AFERRID_11820	ENOG4105CKK	Glycosyl transferase, family 2
AFERRID_11830	ENOG4105M6F	mutator MutT protein
AFERRID_11840	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AFERRID_11850	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AFERRID_11870	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AFERRID_11880	ENOG4107MKT	Stringent starvation protein a
AFERRID_11890	ENOG4108IQE	Amp-dependent synthetase and ligase
AFERRID_11900	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AFERRID_11920	ENOG4108V6E	Cell division protein mraZ
AFERRID_11930	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AFERRID_11950	ENOG4105CJN	penicillin-binding protein
AFERRID_11960	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AFERRID_11970	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AFERRID_11980	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AFERRID_11990	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AFERRID_12000	ENOG4105CNI	cell division protein FtsW
AFERRID_12010	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AFERRID_12020	ENOG4105DFU	Cell wall formation (By similarity)
AFERRID_12030	ENOG4105D4A	Cell wall formation (By similarity)
AFERRID_12040	ENOG4105CPF	Cell wall formation (By similarity)
AFERRID_12050	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AFERRID_12070	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AFERRID_12080	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AFERRID_12110	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AFERRID_12120	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AFERRID_12130	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AFERRID_12140	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AFERRID_12160	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AFERRID_12170	ENOG4105E4C	Lytic transglycosylase catalytic
AFERRID_12190	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AFERRID_12210	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
AFERRID_12220	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AFERRID_12260	ENOG4107TUY	Histidine kinase
AFERRID_12270	ENOG4107QHF	type ii secretion system protein e
AFERRID_12280	ENOG4105E2X	shikimate dehydrogenase
AFERRID_12290	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AFERRID_12300	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AFERRID_12310	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AFERRID_12320	ENOG4105CGK	Exodeoxyribonuclease III
AFERRID_12330	ENOG4108U78	Glutathione S-transferase
AFERRID_12340	ENOG4105D6S	protein involved in catabolism of external DNA
AFERRID_12360	ENOG4105CGK	Exodeoxyribonuclease III
AFERRID_12370	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AFERRID_12380	ENOG4105DND	Transcriptional regulator
AFERRID_12390	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFERRID_12400	ENOG4105C75	arginyL-tRNA synthetase
AFERRID_12430	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AFERRID_12450	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AFERRID_12460	ENOG41082I2	s4 domain protein
AFERRID_12470	ENOG4105DA5	(ABC) transporter
AFERRID_12500	ENOG4107PE3	Mammalian cell entry related domain protein
AFERRID_12510	ENOG4105CY3	ABC transporter, permease
AFERRID_12520	ENOG4105DHJ	ABC, transporter
AFERRID_12530	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AFERRID_12540	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AFERRID_12560	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AFERRID_12600	ENOG4105IH7	synthase
AFERRID_12630	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AFERRID_12680	ENOG4105CVR	type I restriction-modification system
AFERRID_12760	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AFERRID_12780	ENOG4108KU3	Integrase
AFERRID_12790	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AFERRID_12800	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
AFERRID_12810	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AFERRID_12820	ENOG4105CQB	FAD linked oxidase domain protein
AFERRID_12840	ENOG4105XA0	heptosyltransferase ii
AFERRID_12860	ENOG4105DZ2	Transcriptional regulator
AFERRID_12870	ENOG4105D4P	Coproporphyrinogen iii oxidase
AFERRID_12960	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AFERRID_12970	ENOG4107ZVW	dihydroneopterin aldolase
AFERRID_12980	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AFERRID_13000	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AFERRID_13010	ENOG4105ED9	Protein of unknown function (DUF455)
AFERRID_13060	ENOG4105BZS	acriflavin resistance protein
AFERRID_13070	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AFERRID_13090	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AFERRID_13100	ENOG4105E0F	Histidine kinase
AFERRID_13140	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AFERRID_13250	ENOG4105UKP	Protein of unknown function (DUF1778)
AFERRID_13330	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AFERRID_13380	ENOG4108MX3	Polysaccharide Biosynthesis Protein
AFERRID_13440	ENOG4105D3Q	Sugar transferase
AFERRID_13450	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AFERRID_13500	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AFERRID_13520	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AFERRID_13530	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AFERRID_13540	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AFERRID_13570	ENOG4105M8F	Biopolymer transport protein exbD tolR
AFERRID_13580	ENOG4105E02	MotA TolQ exbB proton channel
AFERRID_13590	ENOG4107YD3	Thioesterase
AFERRID_13600	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AFERRID_13610	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AFERRID_13620	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AFERRID_13630	ENOG4105CDY	transcriptional regulatory protein
AFERRID_13650	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AFERRID_13660	ENOG4105C9M	aspartyl-trna synthetase
AFERRID_13680	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AFERRID_13730	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AFERRID_13840	ENOG4105CW7	secretion protein, HlyD family
AFERRID_13860	ENOG4105C5H	ABC transporter
AFERRID_13870	ENOG4105VG0	50S ribosomal protein l34
AFERRID_13890	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AFERRID_13900	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFERRID_13910	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AFERRID_13940	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AFERRID_13950	ENOG4105BZU	Histidine kinase
AFERRID_13960	ENOG41090Y2	cytochrome C
AFERRID_13970	ENOG4105UBK	short-chain dehydrogenase reductase
AFERRID_13980	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AFERRID_13990	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AFERRID_14020	ENOG4105CRE	cytochrome C
AFERRID_14110	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AFERRID_14120	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AFERRID_14150	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AFERRID_14160	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AFERRID_14200	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AFERRID_14260	ENOG4105BZU	Histidine kinase
AFERRID_14270	ENOG4108UYB	regulatoR
AFERRID_14310	ENOG4107RDB	Major Facilitator
AFERRID_14320	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AFERRID_14390	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AFERRID_14410	ENOG41090Y2	cytochrome C
AFERRID_14440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AFERRID_14450	ENOG4105ES5	Histidine kinase
AFERRID_14470	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AFERRID_14480	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AFERRID_14490	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AFERRID_14510	ENOG4105C79	DNA protecting protein DprA
AFERRID_14520	ENOG4108RPN	Protein smg homolog
AFERRID_14540	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AFERRID_14550	ENOG4108Z4U	Ferredoxin
AFERRID_14560	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AFERRID_14570	ENOG4107QMS	site-determining protein
AFERRID_14580	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AFERRID_14610	ENOG4105GVR	general secretion pathway protein D
AFERRID_14720	ENOG4105X0D	Fimbrial protein
AFERRID_14740	ENOG4107QHF	type ii secretion system protein e
AFERRID_14760	ENOG4105BZU	Histidine kinase
AFERRID_14770	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFERRID_14780	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AFERRID_14790	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AFERRID_14800	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AFERRID_14810	ENOG4107FW0	short-chain dehydrogenase reductase
AFERRID_14820	ENOG4105DWF	phosphomethylpyrimidine kinase
AFERRID_14830	ENOG4107S5G	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AFERRID_14840	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AFERRID_14850	ENOG4107ZUX	Histidine triad (HIT) protein
AFERRID_14870	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AFERRID_14890	ENOG4105D52	delta-aminolevulinic acid dehydratase
AFERRID_14930	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AFERRID_14940	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AFERRID_14950	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AFERRID_14960	ENOG4108DMA	Nad-dependent epimerase dehydratase
AFERRID_14980	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
AFERRID_14990	ENOG4107RSS	Hydrogenase accessory protein HypB
AFERRID_15000	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AFERRID_15010	ENOG4105DPX	Hydrogenase, large subunit
AFERRID_15020	ENOG4105DF6	Fe-S oxidoreductase
AFERRID_15040	ENOG4105E3S	small subunit
AFERRID_15080	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AFERRID_15100	ENOG4105CH7	arginosuccinase
AFERRID_15120	ENOG4105E0F	Histidine kinase
AFERRID_15130	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AFERRID_15270	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AFERRID_15310	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AFERRID_15330	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AFERRID_15340	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AFERRID_15360	ENOG4105ECY	inositol monophosphatase
AFERRID_15380	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AFERRID_15390	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AFERRID_15400	ENOG4105BZA	Phosphoglycerate kinase
AFERRID_15410	ENOG4105CA9	Pyruvate kinase
AFERRID_15420	ENOG4105D2N	Aldolase
AFERRID_15430	ENOG4105DJV	ribulose-phosphate 3-epimerase
AFERRID_15440	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AFERRID_15450	ENOG4105CRQ	synthase (Component I)
AFERRID_15460	ENOG4105DDQ	anthranilate synthase
AFERRID_15470	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AFERRID_15480	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AFERRID_15500	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
AFERRID_15510	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
AFERRID_15540	ENOG4105CJ1	ABC, transporter
AFERRID_15560	ENOG41082CH	UPF0145 protein
AFERRID_15600	ENOG4105CYM	Glutathione S-transferase
AFERRID_15620	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AFERRID_15660	ENOG4105DZR	Type I site-specific deoxyribonuclease
AFERRID_15680	ENOG4105EKX	Restriction modification system DNA (Specificity
AFERRID_15740	ENOG4105CVR	type I restriction-modification system
AFERRID_15820	ENOG4105EUB	pirin domain protein
AFERRID_15830	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AFERRID_15890	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AFERRID_15920	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AFERRID_15930	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AFERRID_15940	ENOG4107QJE	Chromosome Partitioning Protein
AFERRID_15950	ENOG4105FA0	parb-like partition protein
AFERRID_15970	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AFERRID_15980	ENOG41082T0	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AFERRID_15990	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AFERRID_16000	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AFERRID_16010	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AFERRID_16020	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AFERRID_16030	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AFERRID_16040	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AFERRID_16050	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AFERRID_16060	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AFERRID_16070	ENOG4105C5I	Dehydrogenase
AFERRID_16080	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AFERRID_16090	ENOG4105DCG	PHP domain protein
AFERRID_16130	ENOG4105C4R	Atp-dependent dna helicase
AFERRID_16140	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AFERRID_16170	ENOG4105CUV	Homoserine Kinase
AFERRID_16200	ENOG4105C2M	dna polymerase I
AFERRID_16210	ENOG4107SVH	Potassium channel protein
AFERRID_16220	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AFERRID_16240	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AFERRID_16250	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AFERRID_16260	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AFERRID_16270	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AFERRID_16280	ENOG4105CHV	Transcription elongation factor NusA
AFERRID_16290	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AFERRID_16300	ENOG41082KD	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AFERRID_16310	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AFERRID_16320	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AFERRID_16330	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AFERRID_16350	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AFERRID_16370	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AFERRID_16380	ENOG4107RZZ	dna polymerase iii epsilon subunit
AFERRID_16410	ENOG4105CDH	Citrulline--aspartate ligase
AFERRID_16420	ENOG4105DBV	ornithine carbamoyltransferase
AFERRID_16430	ENOG4105C8Y	Acetylornithine aminotransferase
AFERRID_16440	ENOG4105CFH	Aspartokinase
AFERRID_16500	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AFERRID_16510	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AFERRID_16520	ENOG4105E9H	Lytic Murein transglycosylase
AFERRID_16530	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AFERRID_16590	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AFERRID_16600	ENOG4108HMX	isocitrate dehydrogenase (NADP)
AFERRID_16610	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AFERRID_16630	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AFERRID_16650	ENOG4108YZA	Nitrogen regulatory protein pii
AFERRID_16660	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AFERRID_16670	ENOG4105C34	Pseudouridine synthase
AFERRID_16680	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AFERRID_16690	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AFERRID_16700	ENOG4107RAT	Ribulose bisphosphate carboxylase large chain, catalytic domain
AFERRID_16710	ENOG41080FP	Hydrolase
AFERRID_16720	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AFERRID_16740	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AFERRID_16760	ENOG4107QTZ	amino acid
AFERRID_16770	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AFERRID_16810	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AFERRID_16830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AFERRID_16850	ENOG4107WP9	Histidine kinase
AFERRID_16860	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AFERRID_16870	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AFERRID_16880	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AFERRID_16890	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AFERRID_16900	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AFERRID_16920	ENOG4105DJF	DNA polymerase III, delta' subunit
AFERRID_16940	ENOG4105C8T	Leucyl-tRNA synthetase
AFERRID_16950	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AFERRID_16960	ENOG4108YYC	ycei family
AFERRID_16980	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AFERRID_17010	ENOG4105C5F	glutamine synthetase
AFERRID_17030	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AFERRID_17040	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AFERRID_17050	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AFERRID_17060	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AFERRID_17080	ENOG4105CHM	Aminotransferase
AFERRID_17090	ENOG4105D6E	homoserine dehydrogenase
AFERRID_17120	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AFERRID_17130	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AFERRID_17140	ENOG4105CRK	lysyL-tRNA synthetase
AFERRID_17150	ENOG4105D60	lipoprotein releasing system transmembrane protein
AFERRID_17160	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AFERRID_17180	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AFERRID_17190	ENOG4105E02	MotA TolQ exbB proton channel
AFERRID_17200	ENOG4109015	Biopolymer transport protein exbD tolR
AFERRID_17230	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AFERRID_17240	ENOG4105W49	UPF0434 protein
AFERRID_17250	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AFERRID_17290	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AFERRID_17330	ENOG4108V5Q	transglutaminase-like protein
AFERRID_17460	ENOG4105CA0	peroxidase
AFERRID_17470	ENOG4108RG0	uracil-dna glycosylase
AFERRID_17480	ENOG4105CNG	UPF0061 protein
AFERRID_17490	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AFERRID_17500	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AFERRID_17510	ENOG4107TF3	peptidylprolyl cis-trans isomerase
AFERRID_17520	ENOG4107S0N	DJ-1 family
AFERRID_17530	ENOG4105CN1	protease
AFERRID_17550	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AFERRID_17580	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AFERRID_17610	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AFERRID_17620	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AFERRID_17630	ENOG4105SYT	Methylenetetrahydrofolate reductase
AFERRID_17670	ENOG4107RIQ	Sulfate adenylate transferase
AFERRID_17680	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AFERRID_17690	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AFERRID_17700	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AFERRID_17720	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AFERRID_17730	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AFERRID_17750	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AFERRID_17760	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AFERRID_17820	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AFERRID_17830	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AFERRID_17840	ENOG4105DTN	riboflavin biosynthesis protein ribF
AFERRID_17850	ENOG4105CJR	Integral membrane protein (MviN
AFERRID_17870	ENOG4105DSJ	YicC domain protein
AFERRID_17880	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AFERRID_17890	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AFERRID_17900	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AFERRID_17910	ENOG4105KME	endoribonuclease L-psp
AFERRID_17930	ENOG4105CB5	ATP-dependent DNA helicase recG
AFERRID_17950	ENOG4105C1Q	protoporphyrinogen oxidase
AFERRID_17960	ENOG4105C02	permease
AFERRID_17980	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
AFERRID_17990	ENOG4105NBF	ammecr1 domain protein
AFERRID_18010	ENOG4105DFG	type I secretion outer membrane protein
AFERRID_18020	ENOG4105CRQ	synthase (Component I)
AFERRID_18050	ENOG4108NF7	phage-type endonuclease
AFERRID_18160	ENOG4105J1P	transposase, IS3 IS911 family protein
AFERRID_18210	ENOG4105C1J	atp-dependent rna helicase
AFERRID_18220	ENOG4105VEQ	Cold shock protein
AFERRID_18230	ENOG4105C25	Primosomal protein n'
AFERRID_18240	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AFERRID_18260	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AFERRID_18280	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AFERRID_18290	ENOG4105C9A	Phoh family
AFERRID_18300	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AFERRID_18310	ENOG4108JU5	Magnesium and cobalt efflux protein
AFERRID_18320	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AFERRID_18330	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AFERRID_18350	ENOG4105DIK	(ABC) transporter
AFERRID_18370	ENOG4105FAV	ABC, transporter
AFERRID_18470	ENOG4107T8Q	Glycosyl transferase (Group 1
AFERRID_18480	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AFERRID_18490	ENOG4105BZ1	(ABC) transporter
AFERRID_18500	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AFERRID_18510	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AFERRID_18530	ENOG4105CVJ	phosphoglycerate mutase
AFERRID_18560	ENOG4105F2W	methyltransferase
AFERRID_18570	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AFERRID_18580	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AFERRID_18600	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AFERRID_18610	ENOG4105E66	phosphoriboisomerase A
AFERRID_18640	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AFERRID_18710	ENOG4105E2S	oxidase) subunit II
AFERRID_18720	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AFERRID_18730	ENOG4105CCU	oxidase (Subunit III)
AFERRID_18750	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AFERRID_18760	ENOG4107RDB	Major Facilitator
AFERRID_18770	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AFERRID_18780	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AFERRID_18790	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AFERRID_18800	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AFERRID_18820	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AFERRID_18830	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AFERRID_18850	ENOG4105DFU	Cell wall formation (By similarity)
AFERRID_18860	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AFERRID_18870	ENOG4105DHJ	ABC, transporter
AFERRID_18880	ENOG4105CY3	ABC transporter, permease
AFERRID_18920	ENOG4105D06	uba thif-type nad fad binding protein
AFERRID_18950	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AFERRID_18960	ENOG4105K63	Thioredoxin
AFERRID_18970	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AFERRID_18980	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AFERRID_18990	ENOG4105C6K	Malic enzyme
AFERRID_19000	ENOG4105IPI	Membrane
AFERRID_19010	ENOG4105C01	Dihydroxy-acid dehydratase
AFERRID_19040	ENOG4107QZM	n-acetylglutamate synthase
AFERRID_19050	ENOG4105M85	Bola protein
AFERRID_19060	ENOG4105K9H	YciI-like protein
AFERRID_19070	ENOG4107835	probably involved in intracellular septation (By similarity)
AFERRID_19090	ENOG4105ECY	inositol monophosphatase
AFERRID_19100	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AFERRID_19120	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AFERRID_19130	ENOG4105C3J	Cysteine desulfurase
AFERRID_19140	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AFERRID_19150	ENOG4108Z4V	iron-sulfur cluster assembly
AFERRID_19170	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AFERRID_19180	ENOG4108ZIT	Ferredoxin, 2FE-2S
AFERRID_19190	ENOG4105WVQ	Fe-S assembly protein IscX
AFERRID_19200	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AFERRID_19210	ENOG4105D78	K07001 NTE family protein
AFERRID_19260	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AFERRID_19290	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
AFERRID_19300	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
AFERRID_19310	ENOG4107QPD	alcohol dehydrogenase
AFERRID_19320	ENOG4105C4W	S-formylglutathione hydrolase
AFERRID_19330	ENOG4107R11	Transcriptional regulator
AFERRID_19360	ENOG4105DPX	Hydrogenase, large subunit
AFERRID_19440	ENOG41083MR	nifu domain-containing protein
AFERRID_19460	ENOG4105C8H	hydrogenase maturation protein Hypf
AFERRID_19470	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
AFERRID_19480	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AFERRID_19490	ENOG4105CQS	hydrogenase expression formation protein HypD
AFERRID_19500	ENOG4105C45	hydrogenase expression formation protein (HypE)
AFERRID_19510	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AFERRID_19570	ENOG4105C7B	Threonine dehydratase
AFERRID_19620	ENOG4108Z20	Acyl-transferase
AFERRID_19630	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AFERRID_19640	ENOG4105BZ8	glutamate synthase
AFERRID_19650	ENOG4105CBC	glutamate synthase
AFERRID_19660	ENOG4105CBC	glutamate synthase
AFERRID_19670	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AFERRID_19680	ENOG4105D49	3-dehydroquinate synthase
AFERRID_19690	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AFERRID_19700	ENOG4105E4G	Type IV pilus
AFERRID_19750	ENOG4108Z6B	deaminase
AFERRID_19780	ENOG4105C98	muts2 protein
AFERRID_19790	ENOG4105C7K	acetolactate synthase
AFERRID_19800	ENOG4108ZP8	Acetolactate synthase small subunit
AFERRID_19810	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AFERRID_19820	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
AFERRID_19830	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AFERRID_19850	ENOG4107YZX	Universal stress protein
AFERRID_19860	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AFERRID_19870	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AFERRID_19900	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AFERRID_19910	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AFERRID_19980	ENOG4105HF0	Membrane
AFERRID_19990	ENOG4105E02	MotA TolQ exbB proton channel
AFERRID_20000	ENOG4105M8F	Biopolymer transport protein exbD tolR
AFERRID_20040	ENOG4107QUY	Guanine deaminase
AFERRID_20050	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AFERRID_20120	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
AFERRID_20160	ENOG41084WP	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AFERRID_20170	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AFERRID_20180	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AFERRID_20200	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AFERRID_20310	ENOG4105C2D	reductase
AFERRID_20460	ENOG4107RDB	Major Facilitator
AFERRID_20470	ENOG4105CMQ	Chloride channel
AFERRID_20490	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AFERRID_20540	ENOG4105W2Z	cytochrome C, class I
AFERRID_20600	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AFERRID_20620	ENOG4105DUM	transcriptional regulator, lysR family
AFERRID_20670	ENOG4105C59	p-type ATPase
AFERRID_20720	ENOG4105C57	major facilitator superfamily
AFERRID_20740	ENOG4107TPS	domain protein
AFERRID_20780	ENOG41090A4	Pterin carbinolamine dehydratase
AFERRID_20800	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AFERRID_20810	ENOG4105DQ4	alcohol dehydrogenase
AFERRID_20820	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AFERRID_20830	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AFERRID_20840	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AFERRID_20850	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AFERRID_20860	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AFERRID_20880	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AFERRID_20920	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AFERRID_20930	ENOG4108MTB	glycosyl transferase family
AFERRID_20940	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AFERRID_20950	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
AFERRID_20960	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AFERRID_21000	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AFERRID_21010	ENOG4105K78	MarR family Transcriptional regulator
AFERRID_21040	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AFERRID_21050	ENOG4105CW7	secretion protein, HlyD family
AFERRID_21070	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFERRID_21080	ENOG4107F9Y	LysR family transcriptional regulator
AFERRID_21140	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AFERRID_21150	ENOG4105DR4	Methyltransferase
AFERRID_21160	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AFERRID_21170	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFERRID_21190	ENOG4105CQC	Prephenate dehydratase
AFERRID_21200	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AFERRID_21210	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AFERRID_21230	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AFERRID_21240	ENOG4105CAT	Cytidine monophosphate kinase
AFERRID_21250	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AFERRID_21260	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AFERRID_21270	ENOG4105CFV	Tetratricopeptide repeat protein
AFERRID_21280	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AFERRID_21290	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AFERRID_21300	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AFERRID_21310	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AFERRID_21320	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AFERRID_21330	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AFERRID_21350	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AFERRID_21410	ENOG41075W9	High frequency lysogenization protein HflD homolog
AFERRID_21420	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AFERRID_21430	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AFERRID_21440	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AFERRID_21450	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AFERRID_21460	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AFERRID_21470	ENOG4108ZAI	phosphatidylglycerophosphatase a
AFERRID_21480	ENOG4105CEV	competence damage-inducible protein
AFERRID_21490	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AFERRID_21500	ENOG4105Y3E	Modulates RecA activity (By similarity)
AFERRID_21510	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AFERRID_21580	ENOG4105E4C	Lytic transglycosylase catalytic
AFERRID_21590	ENOG4105C0D	helicase
AFERRID_21610	ENOG4106ECQ	phosphomannomutase
AFERRID_21630	ENOG4105C5H	ABC transporter
AFERRID_21640	ENOG4105C5H	ABC transporter
AFERRID_21650	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AFERRID_21670	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AFERRID_21680	ENOG4107RGH	Aldehyde dehydrogenase
AFERRID_21710	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AFERRID_21720	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AFERRID_21740	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AFERRID_21750	ENOG4106CJB	Phospholipase Carboxylesterase
AFERRID_21760	ENOG4107QN2	dihydrolipoyl dehydrogenase
AFERRID_21770	ENOG4105DJ9	glucan biosynthesis protein
AFERRID_21790	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AFERRID_21810	ENOG4105M08	Membrane
AFERRID_21830	ENOG4105ERU	peptidase
AFERRID_21840	ENOG4105M00	molybdopterin converting factor, subunit 1
AFERRID_21850	ENOG4108ZAF	Molybdopterin
AFERRID_21860	ENOG4108VPT	UPF0234 protein
AFERRID_21880	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AFERRID_21890	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AFERRID_21900	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AFERRID_21910	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AFERRID_21920	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AFERRID_21930	ENOG4105BZ1	(ABC) transporter
AFERRID_21940	ENOG4108Z4U	Ferredoxin
AFERRID_21950	ENOG4105D3R	alkyl hydroperoxide reductase
AFERRID_21970	ENOG4105DB7	PHP domain protein
AFERRID_21980	ENOG4105IPI	Membrane
AFERRID_22010	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AFERRID_22020	ENOG4105F8V	Hydrolase, tatD family
AFERRID_22030	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AFERRID_22060	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
AFERRID_22080	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AFERRID_22110	ENOG4108YYC	ycei family
AFERRID_22130	ENOG41090MY	MarR family Transcriptional regulator
AFERRID_22140	ENOG4105EQR	Transposase IS116 IS110 IS902
AFERRID_22160	ENOG4108JJ9	ABC, transporter
AFERRID_22180	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AFERRID_22200	ENOG4108IYU	L-aspartate oxidase
AFERRID_22210	ENOG4105EMN	RNA polymerase sigma factor
AFERRID_22230	ENOG4105C0H	protease
AFERRID_22240	ENOG4105C0H	protease
AFERRID_22250	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AFERRID_22260	ENOG4105C3F	Signal peptidase i
AFERRID_22280	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AFERRID_22290	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AFERRID_22300	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AFERRID_22310	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AFERRID_22320	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AFERRID_22330	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AFERRID_22340	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AFERRID_22350	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AFERRID_22360	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AFERRID_22390	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
AFERRID_22410	ENOG4105CVR	type I restriction-modification system
AFERRID_22480	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
AFERRID_22520	ENOG41090Y2	cytochrome C
AFERRID_22550	ENOG4105PGM	cation diffusion facilitator family transporter
AFERRID_22570	ENOG4105C1J	atp-dependent rna helicase
AFERRID_22580	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AFERRID_22590	ENOG4105BZU	Histidine kinase
AFERRID_22600	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AFERRID_22610	ENOG4105C8U	phosphate abc transporter
AFERRID_22620	ENOG4105E2Z	phosphate ABC transporter (Permease
AFERRID_22630	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AFERRID_22640	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AFERRID_22650	ENOG4105C9X	ppx gppa phosphatase
AFERRID_22670	ENOG4105CE9	30S ribosomal protein S2
AFERRID_22680	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AFERRID_22690	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AFERRID_22700	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AFERRID_22710	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AFERRID_22720	ENOG4105KNE	Phosphatidate cytidylyltransferase
AFERRID_22730	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AFERRID_22750	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AFERRID_22770	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AFERRID_22780	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AFERRID_22790	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AFERRID_22800	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
AFERRID_22820	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AFERRID_22840	ENOG4105C0B	DNA polymerase III (alpha subunit)
AFERRID_22850	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AFERRID_22860	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AFERRID_22880	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AFERRID_22890	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
AFERRID_22910	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AFERRID_22920	ENOG4108IAB	Phoh family
AFERRID_22930	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AFERRID_23000	ENOG4105NZG	Ferredoxin
AFERRID_23010	ENOG41090P5	ferredoxin-like protein
AFERRID_23030	ENOG4105C10	Electron transfer flavoprotein
AFERRID_23040	ENOG4105BZJ	Electron transfer flavoprotein
AFERRID_23090	ENOG4105M8F	Biopolymer transport protein exbD tolR
AFERRID_23110	ENOG4105E0A	ABC, transporter
AFERRID_23130	ENOG4108I9K	permease protein
AFERRID_23220	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AFERRID_23240	ENOG410605C	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
AFERRID_23260	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AFERRID_23270	ENOG4105C3J	Cysteine desulfurase
AFERRID_23280	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AFERRID_23290	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
AFERRID_23310	ENOG4105PS4	nifq family
AFERRID_23330	ENOG4105X87	nitrogen fixation
AFERRID_23340	ENOG4108VQE	nitrogen fixation protein
AFERRID_23350	ENOG4108UR2	Nitrogen fixation protein NifX
AFERRID_23360	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
AFERRID_23370	ENOG4105D0B	Nitrogenase protein alpha chain
AFERRID_23390	ENOG4105U82	Ferredoxin
AFERRID_23440	ENOG4108K8Z	nad( )--dinitrogen-reductase ADP-d-ribosyltransferase
AFERRID_23450	ENOG41065RQ	ADP-ribosylation crystallin J1
AFERRID_23460	ENOG4108JUA	Transcriptional regulator
AFERRID_23470	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
AFERRID_23480	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AFERRID_23490	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AFERRID_23520	ENOG4108QWQ	LRV FeS4 cluster domain protein
AFERRID_23550	ENOG4105C3J	Cysteine desulfurase
AFERRID_23580	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AFERRID_23590	ENOG4108ZIT	Ferredoxin, 2FE-2S
AFERRID_23620	ENOG4107XWS	modD protein
AFERRID_23630	ENOG4105F4R	Transcriptional regulator mode
AFERRID_23640	ENOG4105C26	Dehydrogenase
AFERRID_23680	ENOG4108KPW	sugar kinase
AFERRID_23690	ENOG4107STW	synthase
AFERRID_23700	ENOG4105Q84	sucrose synthase
AFERRID_23710	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AFERRID_23730	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AFERRID_23790	ENOG4106CVF	DNA replication protein
AFERRID_23820	ENOG4108UUM	single-stranded DNA-binding protein
AFERRID_23860	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AFERRID_23930	ENOG4108F3G	Type I restriction-modification system, R subunit
AFERRID_23940	ENOG4107XZC	Restriction modification system DNA (Specificity
AFERRID_23950	ENOG4105CVR	type I restriction-modification system
AFERRID_24000	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AFERRID_24010	ENOG4105K70	DNA-binding protein
AFERRID_24200	ENOG4105VUH	addiction module killer protein
AFERRID_24210	ENOG4105YES	addiction module antidote protein
AFERRID_24340	ENOG4105C0H	protease
AFERRID_24360	ENOG4105MYT	Heat shock protein
AFERRID_24390	ENOG4106KE4	Dehydrogenase
AFERRID_24400	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AFERRID_24420	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AFERRID_24440	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
AFERRID_24450	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
AFERRID_24480	ENOG4105EVH	UPF0753 protein
AFERRID_24490	ENOG4108TWJ	NADH dehydrogenase subunit 5
AFERRID_24500	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AFERRID_24510	ENOG4105EU8	FAD linked oxidase domain protein
AFERRID_24520	ENOG4105CQB	FAD linked oxidase domain protein
AFERRID_24590	ENOG4105EKE	dihydroorotase
AFERRID_24600	ENOG4105C01	Dihydroxy-acid dehydratase
AFERRID_24610	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AFERRID_24630	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AFERRID_24640	ENOG4105D2N	Aldolase
AFERRID_24650	ENOG4105FAE	von Willebrand factor, type A
AFERRID_24680	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
AFERRID_24710	ENOG4105KNY	Microcompartments protein
AFERRID_24720	ENOG4105KNY	Microcompartments protein
AFERRID_24730	ENOG4105KNY	Microcompartments protein
AFERRID_24750	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AFERRID_24790	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
AFERRID_24800	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AFERRID_24930	ENOG4105BZU	Histidine kinase
AFERRID_24950	ENOG4105BZU	Histidine kinase
AFERRID_25060	ENOG4108K3A	Glutathione S-transferase
AFERRID_25090	ENOG4105KVH	Transcriptional regulator
AFERRID_25150	ENOG4105FA0	parb-like partition protein
AFERRID_25160	ENOG4107QJE	Chromosome Partitioning Protein
AFERRID_25190	ENOG4108FN7	Aldo keto reductase
AFERRID_25200	ENOG4105BZU	Histidine kinase
AFERRID_25290	ENOG4105YES	addiction module antidote protein
AFERRID_25320	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AFERRID_25370	ENOG4105CYM	Glutathione S-transferase
AFERRID_25540	ENOG4108PQP	glycosyl transferase group 1
AFERRID_25550	ENOG4108MN8	Membrane
AFERRID_25600	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AFERRID_25610	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AFERRID_25640	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AFERRID_25650	ENOG4105DJ0	Poly(A) Polymerase
AFERRID_25670	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AFERRID_25680	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AFERRID_25690	ENOG4105DFP	Integrase
AFERRID_25760	ENOG4106CVF	DNA replication protein
AFERRID_25790	ENOG4108UUM	single-stranded DNA-binding protein
AFERRID_25920	ENOG4108426	dNA-binding protein
AFERRID_25940	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AFERRID_25960	ENOG4105C7H	Helicase, RecD TraA family
AFERRID_26000	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AFERRID_26110	ENOG4105BZU	Histidine kinase
AFERRID_26150	ENOG4108UPT	UPF0178 protein
AFERRID_26160	ENOG4105F9F	transposase
AFERRID_26170	ENOG4105K70	DNA-binding protein
AFERRID_26200	ENOG41082CH	UPF0145 protein
AFERRID_26830	ENOG4108K3A	Glutathione S-transferase
AFERRID_26860	ENOG4105KVH	Transcriptional regulator
AFERRID_26950	ENOG4105FA0	parb-like partition protein
AFERRID_26960	ENOG4107QJE	Chromosome Partitioning Protein
AFERRID_27060	ENOG4105VUH	addiction module killer protein
AFERRID_27070	ENOG4105YES	addiction module antidote protein
AFERRID_27100	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AFERRID_27130	ENOG4105C2M	dna polymerase I
AFERRID_27170	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AFERRID_27180	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AFERRID_27210	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AFERRID_27220	ENOG4108SB3	DoxX Family
AFERRID_27250	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFERRID_27260	ENOG4108YV4	Universal stress protein
AFERRID_27270	ENOG4105EMU	Dehydrogenase
AFERRID_27280	ENOG4105CPC	Aldo Keto reductase
AFERRID_27340	ENOG4105C4W	S-formylglutathione hydrolase
AFERRID_27350	ENOG4107QPD	alcohol dehydrogenase
AFERRID_27360	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AFERRID_27380	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AFERRID_27390	ENOG4106KE4	Dehydrogenase
AFERRID_27410	ENOG4107YZX	Universal stress protein
AFERRID_27420	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFERRID_27510	ENOG4107QTZ	amino acid
AFERRID_27520	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AFERRID_27530	ENOG4105EGS	Mechanosensitive ion channel
AFERRID_27570	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AFERRID_27580	ENOG4108Z4T	Peptidase M50
AFERRID_27590	ENOG4105C31	Tryptophanyl-tRNA synthetase
AFERRID_27600	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AFERRID_27610	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AFERRID_27630	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
AFERRID_27640	ENOG4105FE9	pseudouridine synthase
AFERRID_27650	ENOG4105CSM	endonuclease III
AFERRID_27680	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFERRID_27760	ENOG4105DE4	1-phosphofructokinase
AFERRID_27770	ENOG4107QYA	phosphate
AFERRID_27780	ENOG4105C54	Major Facilitator superfamily
AFERRID_27790	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AFERRID_27820	ENOG4108JYK	Dehydrogenase
AFERRID_27840	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AFERRID_27880	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AFERRID_27890	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AFERRID_27930	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AFERRID_27940	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AFERRID_27950	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AFERRID_27970	ENOG4105K4H	Nlp p60 protein
AFERRID_28070	ENOG4107QTH	restriction modification system DNA specificity domain
AFERRID_28150	ENOG4105EV9	Alpha Beta Hydrolase
AFERRID_28180	ENOG41080VW	acetyltransferase
AFERRID_28370	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AFERRID_28400	ENOG4105C0B	DNA polymerase III (alpha subunit)
AFERRID_28420	ENOG4105CD8	aminopeptidase N
AFERRID_28450	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AFERRID_28460	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AFERRID_28470	ENOG4105BZS	acriflavin resistance protein
AFERRID_28480	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AFERRID_28510	ENOG4108UHJ	MAF-like protein
AFERRID_28520	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AFERRID_28530	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AFERRID_28540	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AFERRID_28550	ENOG4107QJR	hflk protein
AFERRID_28560	ENOG4105EPW	hflc protein
AFERRID_28570	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
AFERRID_28580	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
AFERRID_28610	ENOG4105CSR	polyphosphate kinase 2
AFERRID_28620	ENOG4107QN2	dihydrolipoyl dehydrogenase
AFERRID_28640	ENOG4105CEV	competence damage-inducible protein
AFERRID_28650	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AFERRID_28660	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AFERRID_28680	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
AFERRID_28690	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AFERRID_28720	ENOG41082GS	50S ribosomal protein L32
AFERRID_28730	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AFERRID_28740	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AFERRID_28750	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AFERRID_28760	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AFERRID_28770	ENOG4105CHR	reductase
AFERRID_28780	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AFERRID_28790	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AFERRID_28810	ENOG4105HHA	aminodeoxychorismate lyase
AFERRID_28820	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AFERRID_28830	ENOG4107QRG	dna polymerase iii
AFERRID_28850	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AFERRID_28860	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AFERRID_28870	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AFERRID_28890	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AFERRID_28900	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AFERRID_28920	ENOG4105K8N	protein family UPF0079, ATPase
AFERRID_28930	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AFERRID_28940	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AFERRID_28960	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AFERRID_28970	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AFERRID_28990	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AFERRID_29000	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AFERRID_29010	ENOG4105CUT	histidyl-tRNA synthetase
AFERRID_29040	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AFERRID_29090	ENOG4105C8U	phosphate abc transporter
AFERRID_29140	ENOG4105EJ9	Membrane
AFERRID_29320	ENOG4108IJF	Heavy metal efflux pump, CzcA
AFERRID_29350	ENOG4108V1U	phospholipid-binding protein
AFERRID_29360	ENOG4108Z4U	Ferredoxin
AFERRID_29400	ENOG4105D03	DNA-3-methyladenine glycosylase II
AFERRID_29420	ENOG4105K64	Glycosyl transferase, family 2
AFERRID_29480	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AFERRID_29510	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AFERRID_29530	ENOG4105CFU	surface antigen
AFERRID_29570	ENOG4105W2Z	cytochrome C, class I
AFERRID_29620	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AFERRID_29640	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFERRID_29650	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AFERRID_29670	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AFERRID_29680	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AFERRID_29690	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AFERRID_29700	ENOG4105CTB	Polyprenyl synthetase
AFERRID_29720	ENOG4105EU0	Major facilitator Superfamily
AFERRID_29740	ENOG41080RH	Thioredoxin
AFERRID_29750	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AFERRID_29760	ENOG4105DZG	Dehydrogenase
AFERRID_29790	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AFERRID_29800	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AFERRID_29820	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AFERRID_29840	ENOG4105J0Q	Transcriptional regulator
AFERRID_29880	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AFERRID_29980	ENOG41060GW	
AFERRID_30000	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AFERRID_30060	ENOG4105BZ1	(ABC) transporter
AFERRID_30070	ENOG4105BZ1	(ABC) transporter
AFERRID_30120	ENOG4108J5G	6-phosphogluconate dehydrogenase
AFERRID_30130	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AFERRID_30140	ENOG41080HT	Transcriptional regulator, arsr family
AFERRID_30150	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AFERRID_t00250	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)