locus-tag	class	description
Acife_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Acife_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Acife_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Acife_0004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Acife_0007	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Acife_0008	ENOG4107QMS	site-determining protein
Acife_0009	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Acife_0010	ENOG4108Z4U	Ferredoxin
Acife_0012	ENOG4108RPN	Protein smg homolog
Acife_0013	ENOG4105C79	DNA protecting protein DprA
Acife_0015	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Acife_0016	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Acife_0017	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Acife_0019	ENOG4105ES5	Histidine kinase
Acife_0020	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Acife_0022	ENOG4105C8Q	Methyl-accepting chemotaxis
Acife_0024	ENOG4105E2V	Glycosyltransferase 36
Acife_0027	ENOG4105BZU	Histidine kinase
Acife_0028	ENOG4105KUZ	arsenate reductase
Acife_0030	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
Acife_0032	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Acife_0033	ENOG4107ZVW	dihydroneopterin aldolase
Acife_0034	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Acife_0035	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Acife_0036	ENOG4105ED9	Protein of unknown function (DUF455)
Acife_0039	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
Acife_0049	ENOG4105E09	nadh pyrophosphatase
Acife_0050	ENOG4105BZS	acriflavin resistance protein
Acife_0053	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Acife_0054	ENOG4105E0F	Histidine kinase
Acife_0055	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Acife_0056	ENOG41087YS	Phage shock protein A
Acife_0057	ENOG41082CH	UPF0145 protein
Acife_0064	ENOG4106FTQ	Taurine ABC transporter, periplasmic
Acife_0067	ENOG4108Z4U	Ferredoxin
Acife_0071	ENOG4105FDP	GntR family transcriptional regulator
Acife_0072	ENOG4105D4P	Coproporphyrinogen iii oxidase
Acife_0073	ENOG4105DZ2	Transcriptional regulator
Acife_0075	ENOG4105XA0	heptosyltransferase ii
Acife_0077	ENOG4105CQB	FAD linked oxidase domain protein
Acife_0078	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Acife_0079	ENOG41082RQ	UPF0102 protein
Acife_0080	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
Acife_0081	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Acife_0082	ENOG4105CA0	peroxidase
Acife_0084	ENOG4105CRE	cytochrome C
Acife_0085	ENOG4105VEQ	Cold shock protein
Acife_0087	ENOG4105BZU	Histidine kinase
Acife_0088	ENOG4105C03	ribonuclease
Acife_0089	ENOG4108Z03	MAF-like protein
Acife_0092	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Acife_0094	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Acife_0096	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Acife_0097	ENOG4105E0X	reductase
Acife_0099	ENOG4105DJ9	glucan biosynthesis protein
Acife_0104	ENOG4105M8F	Biopolymer transport protein exbD tolR
Acife_0111	ENOG4107QYX	exodeoxyribonuclease v alpha
Acife_0112	ENOG4107QKA	exodeoxyribonuclease V beta
Acife_0113	ENOG4105DSY	exodeoxyribonuclease V, gamma
Acife_0115	ENOG4105E18	UPF0276 protein
Acife_0117	ENOG4105D1S	lipid A biosynthesis
Acife_0120	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Acife_0122	ENOG4105WMR	Protein CrcB homolog
Acife_0130	ENOG4108MX3	Polysaccharide Biosynthesis Protein
Acife_0132	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Acife_0134	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Acife_0135	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Acife_0136	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
Acife_0138	ENOG4105M8F	Biopolymer transport protein exbD tolR
Acife_0139	ENOG4105E02	MotA TolQ exbB proton channel
Acife_0140	ENOG4107YD3	Thioesterase
Acife_0141	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Acife_0142	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Acife_0143	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Acife_0144	ENOG4105CDY	transcriptional regulatory protein
Acife_0146	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Acife_0147	ENOG4105C9M	aspartyl-trna synthetase
Acife_0149	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
Acife_0151	ENOG4105C5H	ABC transporter
Acife_0152	ENOG4105VG0	50S ribosomal protein l34
Acife_0154	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Acife_0155	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Acife_0156	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Acife_0161	ENOG4105DZR	Type I site-specific deoxyribonuclease
Acife_0168	ENOG4105CJ1	ABC, transporter
Acife_0169	ENOG4105DHZ	alpha beta
Acife_0171	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
Acife_0172	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
Acife_0174	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Acife_0175	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Acife_0176	ENOG4105DDQ	anthranilate synthase
Acife_0181	ENOG4105CRQ	synthase (Component I)
Acife_0182	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Acife_0183	ENOG4105DJV	ribulose-phosphate 3-epimerase
Acife_0184	ENOG4105D2N	Aldolase
Acife_0185	ENOG4105CA9	Pyruvate kinase
Acife_0186	ENOG4105BZA	Phosphoglycerate kinase
Acife_0187	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Acife_0188	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Acife_0190	ENOG4105ECY	inositol monophosphatase
Acife_0192	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Acife_0193	ENOG4105D7N	magnesium and cobalt transport protein CorA
Acife_0194	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Acife_0196	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Acife_0199	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Acife_0202	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
Acife_0205	ENOG410870W	N-acetyltransferase
Acife_0208	ENOG4108UPT	UPF0178 protein
Acife_0215	ENOG4108RNG	Permease of the drug metabolite transporter
Acife_0217	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Acife_0218	ENOG4105E0F	Histidine kinase
Acife_0220	ENOG4105CH7	arginosuccinase
Acife_0222	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Acife_0223	ENOG4105C89	phosphohexose isomerase
Acife_0224	ENOG4105DZ1	carboxypeptidase
Acife_0225	ENOG4108K3A	Glutathione S-transferase
Acife_0226	ENOG4105CS1	NAD(P)H quinone oxidoreductase
Acife_0228	ENOG4108YYC	ycei family
Acife_0230	ENOG4105C59	p-type ATPase
Acife_0233	ENOG4107SVH	Potassium channel protein
Acife_0235	ENOG4105K6T	rare lipoprotein A
Acife_0238	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Acife_0239	ENOG4105BZU	Histidine kinase
Acife_0240	ENOG4105BZU	Histidine kinase
Acife_0243	ENOG4105BZU	Histidine kinase
Acife_0244	ENOG4108YZA	Nitrogen regulatory protein pii
Acife_0246	ENOG4105ED1	spovr family
Acife_0247	ENOG4106AKX	UPF0229 protein
Acife_0248	ENOG4105BZU	Histidine kinase
Acife_0249	ENOG4105CYN	Serine protein kinase
Acife_0256	ENOG4105CUX	Signal transduction histidine kinase
Acife_0257	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Acife_0259	ENOG4105EAH	synthase
Acife_0261	ENOG4105CJN	penicillin-binding protein
Acife_0264	ENOG4105C5H	ABC transporter
Acife_0266	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Acife_0281	ENOG4105CDV	Ompa motb domain protein
Acife_0289	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Acife_0290	ENOG4105K5M	30s ribosomal protein S16
Acife_0292	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Acife_0293	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Acife_0295	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Acife_0296	ENOG4105C0H	protease
Acife_0297	ENOG4107QR8	Thioredoxin
Acife_0299	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Acife_0300	ENOG4108UUM	single-stranded DNA-binding protein
Acife_0301	ENOG4105CVR	type I restriction-modification system
Acife_0306	ENOG4105DZR	Type I site-specific deoxyribonuclease
Acife_0308	ENOG4106BRA	Membrane
Acife_0309	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Acife_0310	ENOG4105DKQ	ROK family
Acife_0311	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
Acife_0313	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Acife_0314	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Acife_0318	ENOG4105C6T	cysteine synthase
Acife_0322	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Acife_0324	ENOG4105C0X	amino acid
Acife_0325	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
Acife_0326	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Acife_0329	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Acife_0330	ENOG4105CDU	Replicative dna helicase
Acife_0331	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Acife_0332	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Acife_0334	ENOG4107RAQ	aminopeptidase
Acife_0337	ENOG4108303	d-xylulose 5-phosphate d-fructose 6-phosphate phosphoketolase
Acife_0357	ENOG4105EMU	Dehydrogenase
Acife_0359	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Acife_0366	ENOG4108I5C	dEAD DEAH box helicase
Acife_0367	ENOG4105C0D	helicase
Acife_0414	ENOG4105WJ3	XRE family Transcriptional regulator
Acife_0415	ENOG4105RT5	Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation
Acife_0420	ENOG4106CVF	DNA replication protein
Acife_0443	ENOG4105DUM	transcriptional regulator, lysR family
Acife_0444	ENOG4108TWJ	NADH dehydrogenase subunit 5
Acife_0445	ENOG4105EVH	UPF0753 protein
Acife_0448	ENOG4105EKE	dihydroorotase
Acife_0450	ENOG41090MY	MarR family Transcriptional regulator
Acife_0452	ENOG4108YYC	ycei family
Acife_0456	ENOG4105BZU	Histidine kinase
Acife_0460	ENOG4105EQR	Transposase IS116 IS110 IS902
Acife_0487	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Acife_0490	ENOG4105PGM	cation diffusion facilitator family transporter
Acife_0492	ENOG4105C3J	Cysteine desulfurase
Acife_0500	ENOG4108IJF	Heavy metal efflux pump, CzcA
Acife_0520	ENOG4106D4I	domain protein
Acife_0521	ENOG4107VRP	DNA repair exonuclease
Acife_0523	ENOG4105C0D	helicase
Acife_0529	ENOG4105BZU	Histidine kinase
Acife_0541	ENOG4105CZX	twitching motility protein
Acife_0544	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Acife_0545	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Acife_0546	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
Acife_0547	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
Acife_0548	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Acife_0549	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Acife_0550	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Acife_0551	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Acife_0552	ENOG410890F	Dynamin family
Acife_0553	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
Acife_0554	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Acife_0555	ENOG4106H78	methyltransferase
Acife_0556	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Acife_0557	ENOG4105CAK	Cell division ATP-binding protein ftsE
Acife_0558	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Acife_0559	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acife_0561	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Acife_0562	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Acife_0563	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Acife_0566	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Acife_0569	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Acife_0570	ENOG4105NWN	ApaG protein
Acife_0571	ENOG4105HBR	Rna-binding protein
Acife_0572	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Acife_0574	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Acife_0575	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
Acife_0577	ENOG4105CSM	endonuclease III
Acife_0579	ENOG4105CY0	Metallo-Beta-Lactamase
Acife_0580	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Acife_0584	ENOG4105DPN	Oligoendopeptidase f
Acife_0585	ENOG4105C9Q	fumarate hydratase class II
Acife_0586	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Acife_0587	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Acife_0588	ENOG4105KDC	50s ribosomal protein l28
Acife_0589	ENOG4105W0E	50S ribosomal protein L33
Acife_0590	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Acife_0591	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Acife_0592	ENOG4105CFG	Acts as a chaperone (By similarity)
Acife_0593	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Acife_0594	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Acife_0597	ENOG4105DHP	deoxycytidine triphosphate deaminase
Acife_0602	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Acife_0606	ENOG4105CG3	alpha amylase, catalytic region
Acife_0608	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Acife_0609	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
Acife_0614	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Acife_0615	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Acife_0616	ENOG4105UBK	short-chain dehydrogenase reductase
Acife_0617	ENOG41090Y2	cytochrome C
Acife_0621	ENOG4107R11	Transcriptional regulator
Acife_0622	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Acife_0623	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Acife_0624	ENOG4105E9H	Lytic Murein transglycosylase
Acife_0625	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Acife_0626	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Acife_0627	ENOG4108HMX	isocitrate dehydrogenase (NADP)
Acife_0628	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Acife_0630	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Acife_0631	ENOG4105C4K	Nad synthetase
Acife_0632	ENOG4108YZA	Nitrogen regulatory protein pii
Acife_0633	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Acife_0634	ENOG4105C34	Pseudouridine synthase
Acife_0635	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Acife_0636	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
Acife_0637	ENOG4107RAT	Ribulose bisphosphate carboxylase large chain, catalytic domain
Acife_0638	ENOG41080FP	Hydrolase
Acife_0639	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
Acife_0641	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Acife_0642	ENOG4105E02	MotA TolQ exbB proton channel
Acife_0643	ENOG4105M8F	Biopolymer transport protein exbD tolR
Acife_0646	ENOG4107QUY	Guanine deaminase
Acife_0647	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Acife_0649	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
Acife_0653	ENOG4105CWN	amidohydrolase
Acife_0654	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
Acife_0658	ENOG41084WP	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Acife_0659	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Acife_0660	ENOG4105EGI	Transcriptional regulator
Acife_0663	ENOG4105KG3	cytidine deaminase
Acife_0669	ENOG4105EKX	Restriction modification system DNA (Specificity
Acife_0675	ENOG4105DZR	Type I site-specific deoxyribonuclease
Acife_0677	ENOG4106FC9	Protein  of unknown function (DUF3018)
Acife_0680	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Acife_0682	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Acife_0684	ENOG4107WP9	Histidine kinase
Acife_0685	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Acife_0686	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Acife_0687	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Acife_0688	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Acife_0689	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Acife_0697	ENOG4105C59	p-type ATPase
Acife_0698	ENOG41067VN	Glutaredoxin
Acife_0707	ENOG4105C4W	S-formylglutathione hydrolase
Acife_0708	ENOG4107QPD	alcohol dehydrogenase
Acife_0709	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
Acife_0710	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
Acife_0717	ENOG4105XB7	anti-repressor protein
Acife_0720	ENOG4105EUP	HipA domain protein
Acife_0724	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Acife_0728	ENOG4105C7H	Helicase, RecD TraA family
Acife_0730	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Acife_0734	ENOG4105BZU	Histidine kinase
Acife_0735	ENOG4108YZA	Nitrogen regulatory protein pii
Acife_0747	ENOG4105DB4	
Acife_0751	ENOG4108R7K	Metal Dependent Phosphohydrolase
Acife_0752	ENOG4105K70	DNA-binding protein
Acife_0756	ENOG4105MN3	Resolvase
Acife_0757	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
Acife_0759	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Acife_0761	ENOG4108WQI	RNA Polymerase
Acife_0768	ENOG4105E18	UPF0276 protein
Acife_0774	ENOG4108XDN	Transcriptional regulator
Acife_0782	ENOG4107QX9	Thiol disulfide interChange protein
Acife_0783	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Acife_0784	ENOG4105C89	phosphohexose isomerase
Acife_0785	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Acife_0787	ENOG4107QN2	dihydrolipoyl dehydrogenase
Acife_0792	ENOG4105C5I	Dehydrogenase
Acife_0793	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Acife_0800	ENOG4105CPP	Dehydrogenase, E1 component
Acife_0801	ENOG4108JYK	Dehydrogenase
Acife_0803	ENOG4105CSR	polyphosphate kinase 2
Acife_0804	ENOG4105BZA	Phosphoglycerate kinase
Acife_0805	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Acife_0812	ENOG4108IJF	Heavy metal efflux pump, CzcA
Acife_0832	ENOG4105CVR	type I restriction-modification system
Acife_0835	ENOG4107QTH	restriction modification system DNA specificity domain
Acife_0836	ENOG4105YAJ	CopG Arc MetJ
Acife_0837	ENOG4105VV5	Plasmid stabilization system
Acife_0838	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
Acife_0842	ENOG4105DJF	DNA polymerase III, delta' subunit
Acife_0844	ENOG4105C8T	Leucyl-tRNA synthetase
Acife_0847	ENOG41084HI	prevent-host-death family
Acife_0852	ENOG4105CHH	sulfate transporter
Acife_0853	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Acife_0856	ENOG4105C5F	glutamine synthetase
Acife_0861	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Acife_0862	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acife_0864	ENOG4105CHM	Aminotransferase
Acife_0865	ENOG4105D6E	homoserine dehydrogenase
Acife_0873	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Acife_0878	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
Acife_0881	ENOG4105D85	methylase
Acife_0882	ENOG4105DFS	Conserved Protein
Acife_0883	ENOG4105F6A	helicase
Acife_0884	ENOG4105ECI	YeeC-like protein
Acife_0886	ENOG4105C3J	Cysteine desulfurase
Acife_0896	ENOG4108IJF	Heavy metal efflux pump, CzcA
Acife_0905	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Acife_0915	ENOG4105BZU	Histidine kinase
Acife_0916	ENOG4107QZ7	Cellulose synthase catalytic subunit
Acife_0917	ENOG4105BZU	Histidine kinase
Acife_0919	ENOG4105EQR	Transposase IS116 IS110 IS902
Acife_0926	ENOG4105CRK	lysyL-tRNA synthetase
Acife_0927	ENOG4105D60	lipoprotein releasing system transmembrane protein
Acife_0928	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Acife_0930	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
Acife_0931	ENOG4105E02	MotA TolQ exbB proton channel
Acife_0932	ENOG4109015	Biopolymer transport protein exbD tolR
Acife_0935	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Acife_0936	ENOG4105W49	UPF0434 protein
Acife_0937	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Acife_0949	ENOG4105EKQ	RNA-directed DNA polymerase
Acife_0954	ENOG4105UKP	Protein of unknown function (DUF1778)
Acife_0956	ENOG4108RG0	uracil-dna glycosylase
Acife_0957	ENOG4105CNG	UPF0061 protein
Acife_0958	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Acife_0959	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Acife_0960	ENOG4107TF3	peptidylprolyl cis-trans isomerase
Acife_0961	ENOG4107S0N	DJ-1 family
Acife_0962	ENOG4105CN1	protease
Acife_0964	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Acife_0967	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Acife_0970	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Acife_0971	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Acife_0972	ENOG4105SYT	Methylenetetrahydrofolate reductase
Acife_0975	ENOG4105C1J	atp-dependent rna helicase
Acife_0976	ENOG4105VEQ	Cold shock protein
Acife_0977	ENOG4105C25	Primosomal protein n'
Acife_0978	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
Acife_0980	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Acife_0982	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Acife_0983	ENOG4105C9A	Phoh family
Acife_0984	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Acife_0985	ENOG4108JU5	Magnesium and cobalt efflux protein
Acife_0986	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Acife_0987	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Acife_0989	ENOG4105DIK	(ABC) transporter
Acife_0991	ENOG4105FAV	ABC, transporter
Acife_0999	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Acife_1000	ENOG4107T8Q	Glycosyl transferase (Group 1
Acife_1001	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Acife_1002	ENOG4105BZ1	(ABC) transporter
Acife_1003	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Acife_1005	ENOG4105CVJ	phosphoglycerate mutase
Acife_1008	ENOG4105F2W	methyltransferase
Acife_1009	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Acife_1010	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Acife_1012	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
Acife_1013	ENOG4105E66	phosphoriboisomerase A
Acife_1015	ENOG4105E2S	oxidase) subunit II
Acife_1016	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Acife_1017	ENOG4105CCU	oxidase (Subunit III)
Acife_1020	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Acife_1022	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Acife_1023	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Acife_1024	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Acife_1025	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Acife_1029	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Acife_1030	ENOG4105CCU	oxidase (Subunit III)
Acife_1044	ENOG4105DVE	abc transporter atp-binding protein
Acife_1053	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
Acife_1058	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
Acife_1059	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Acife_1060	ENOG4105E0F	Histidine kinase
Acife_1064	ENOG4105M8F	Biopolymer transport protein exbD tolR
Acife_1068	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Acife_1069	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
Acife_1070	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Acife_1071	ENOG4105C12	Phosphoribosylglycinamide synthetase
Acife_1072	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Acife_1075	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
Acife_1076	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Acife_1077	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Acife_1080	ENOG4105C08	Histidine kinase
Acife_1085	ENOG4107QTZ	amino acid
Acife_1088	ENOG4105BZU	Histidine kinase
Acife_1089	ENOG4108JQC	penicillin-binding protein 1A
Acife_1090	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Acife_1091	ENOG4105C8N	cysteinyl-tRNA synthetase
Acife_1092	ENOG4107QQB	Ribonuclease E
Acife_1093	ENOG4105EI2	Pseudouridine synthase
Acife_1095	ENOG4105ECY	inositol monophosphatase
Acife_1096	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
Acife_1098	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Acife_1099	ENOG4105C3J	Cysteine desulfurase
Acife_1100	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
Acife_1101	ENOG4108Z4V	iron-sulfur cluster assembly
Acife_1102	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
Acife_1103	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
Acife_1104	ENOG4108ZIT	Ferredoxin, 2FE-2S
Acife_1105	ENOG4105WVQ	Fe-S assembly protein IscX
Acife_1106	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Acife_1107	ENOG4105D78	K07001 NTE family protein
Acife_1110	ENOG4105CVR	type I restriction-modification system
Acife_1111	ENOG4105C4W	S-formylglutathione hydrolase
Acife_1112	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Acife_1113	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Acife_1115	ENOG4105DFU	Cell wall formation (By similarity)
Acife_1116	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Acife_1117	ENOG4105DHJ	ABC, transporter
Acife_1118	ENOG4105CY3	ABC transporter, permease
Acife_1122	ENOG4105D06	uba thif-type nad fad binding protein
Acife_1126	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Acife_1127	ENOG4105K63	Thioredoxin
Acife_1128	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Acife_1129	ENOG4105VFB	Binds the 23S rRNA (By similarity)
Acife_1130	ENOG4105C6K	Malic enzyme
Acife_1131	ENOG4105IPI	Membrane
Acife_1132	ENOG4105C01	Dihydroxy-acid dehydratase
Acife_1134	ENOG4107QZM	n-acetylglutamate synthase
Acife_1135	ENOG4105M85	Bola protein
Acife_1136	ENOG4105K9H	YciI-like protein
Acife_1137	ENOG4107835	probably involved in intracellular septation (By similarity)
Acife_1140	ENOG4105YES	addiction module antidote protein
Acife_1142	ENOG41060A7	DNA polymerase beta domain protein region
Acife_1153	ENOG4105XMH	SpoVT AbrB domain protein
Acife_1155	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Acife_1158	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
Acife_1159	ENOG4108DMA	Nad-dependent epimerase dehydratase
Acife_1166	ENOG4105D3Q	Sugar transferase
Acife_1167	ENOG4108KBE	Glycosyl transferase, family 2
Acife_1168	ENOG4108TJN	glycosyl transferase group 1
Acife_1171	ENOG4105K64	Glycosyl transferase, family 2
Acife_1175	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Acife_1176	ENOG4105FAW	cDP-glucose 4,6-dehydratase
Acife_1177	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
Acife_1178	ENOG4105CMR	udp-glucose 4-epimerase
Acife_1180	ENOG4108F2G	Chain length determinant protein
Acife_1194	ENOG4105D3Q	Sugar transferase
Acife_1208	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Acife_1209	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
Acife_1212	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Acife_1213	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Acife_1214	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Acife_1216	ENOG4105MYG	DNA polymerase iii, chi subunit
Acife_1217	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Acife_1218	ENOG4108M8S	permease YjgP YjgQ family protein
Acife_1223	ENOG41087PB	Frataxin-like domain
Acife_1224	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Acife_1225	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Acife_1227	ENOG4105E0C	molybdate abc transporter
Acife_1228	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Acife_1229	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
Acife_1230	ENOG4105C4R	Atp-dependent dna helicase
Acife_1232	ENOG4105DWY	Agmatine deiminase
Acife_1233	ENOG4105I08	Pseudouridine synthase
Acife_1235	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Acife_1237	ENOG4107BJW	polysaccharide deacetylase
Acife_1238	ENOG4105I7M	spermidine synthase
Acife_1239	ENOG4105DUM	transcriptional regulator, lysR family
Acife_1242	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
Acife_1243	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acife_1244	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acife_1245	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Acife_1247	ENOG4107TDF	Formate hydrogenlyase subunit 4
Acife_1248	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Acife_1249	ENOG4108JCI	Transcriptional regulator
Acife_1250	ENOG4105C3G	gtp-binding protein
Acife_1251	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Acife_1252	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Acife_1253	ENOG4105CJN	penicillin-binding protein
Acife_1256	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Acife_1260	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Acife_1264	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Acife_1267	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
Acife_1268	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Acife_1274	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Acife_1275	ENOG410901P	UPF0249 protein
Acife_1278	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Acife_1281	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Acife_1282	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Acife_1283	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Acife_1285	ENOG4105C1J	atp-dependent rna helicase
Acife_1286	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Acife_1287	ENOG4105BZU	Histidine kinase
Acife_1288	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
Acife_1289	ENOG4105C8U	phosphate abc transporter
Acife_1290	ENOG4105E2Z	phosphate ABC transporter (Permease
Acife_1291	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Acife_1292	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Acife_1293	ENOG4105C9X	ppx gppa phosphatase
Acife_1296	ENOG4105CE9	30S ribosomal protein S2
Acife_1297	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Acife_1298	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Acife_1299	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Acife_1300	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Acife_1301	ENOG4105KNE	Phosphatidate cytidylyltransferase
Acife_1302	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Acife_1304	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Acife_1306	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Acife_1307	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Acife_1308	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Acife_1309	ENOG4105D9R	oxidoreductase
Acife_1312	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Acife_1313	ENOG4105C0B	DNA polymerase III (alpha subunit)
Acife_1314	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Acife_1315	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Acife_1316	ENOG4105CD3	dihydroorotase
Acife_1317	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Acife_1318	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
Acife_1319	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
Acife_1322	ENOG4107EEX	Cellulose synthase regulator protein
Acife_1323	ENOG4107QZ7	Cellulose synthase catalytic subunit
Acife_1324	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Acife_1328	ENOG4105BZU	Histidine kinase
Acife_1337	ENOG4105BZU	Histidine kinase
Acife_1338	ENOG4105BZU	Histidine kinase
Acife_1342	ENOG4105PGM	cation diffusion facilitator family transporter
Acife_1343	ENOG4107TPS	domain protein
Acife_1345	ENOG4105C57	major facilitator superfamily
Acife_1355	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Acife_1356	ENOG4105DQ4	alcohol dehydrogenase
Acife_1357	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Acife_1358	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Acife_1359	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Acife_1360	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
Acife_1361	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Acife_1363	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Acife_1366	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Acife_1367	ENOG41080HT	Transcriptional regulator, arsr family
Acife_1368	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
Acife_1369	ENOG4108J5G	6-phosphogluconate dehydrogenase
Acife_1372	ENOG4105BZ1	(ABC) transporter
Acife_1385	ENOG4105DR4	Methyltransferase
Acife_1386	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Acife_1387	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Acife_1388	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Acife_1389	ENOG4105CQC	Prephenate dehydratase
Acife_1390	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Acife_1391	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Acife_1393	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Acife_1394	ENOG4105CAT	Cytidine monophosphate kinase
Acife_1395	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Acife_1396	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Acife_1397	ENOG4105CFV	Tetratricopeptide repeat protein
Acife_1398	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Acife_1399	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Acife_1400	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Acife_1401	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Acife_1402	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Acife_1403	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Acife_1404	ENOG4105K70	DNA-binding protein
Acife_1405	ENOG4105EIN	peptidylprolyl cis-trans isomerase
Acife_1407	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Acife_1409	ENOG4105CD8	aminopeptidase N
Acife_1411	ENOG4105I7R	Adenylate cyclase
Acife_1413	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Acife_1414	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Acife_1415	ENOG4105BZS	acriflavin resistance protein
Acife_1416	ENOG410624X	efflux transporter, rnd family, mfp subunit
Acife_1419	ENOG4108UHJ	MAF-like protein
Acife_1420	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Acife_1421	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Acife_1422	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Acife_1423	ENOG4107QJR	hflk protein
Acife_1424	ENOG4105EPW	hflc protein
Acife_1425	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Acife_1429	ENOG4105CSR	polyphosphate kinase 2
Acife_1430	ENOG4107QN2	dihydrolipoyl dehydrogenase
Acife_1431	ENOG4107TH8	cina domain protein
Acife_1432	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Acife_1433	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Acife_1435	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
Acife_1436	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Acife_1437	ENOG4107S2Z	UPF0761 membrane protein
Acife_1439	ENOG41082GS	50S ribosomal protein L32
Acife_1440	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Acife_1441	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Acife_1442	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Acife_1443	ENOG4105CHR	reductase
Acife_1444	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Acife_1445	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Acife_1447	ENOG4105HHA	aminodeoxychorismate lyase
Acife_1448	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Acife_1449	ENOG4107QRG	dna polymerase iii
Acife_1457	ENOG41076YT	nitrate reductase, gamma subunit
Acife_1458	ENOG4105R3A	Nitrate reductase
Acife_1459	ENOG4108IUE	nitrate reductase beta subunit
Acife_1460	ENOG4105CRU	nitrate reductase, alpha subunit
Acife_1474	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Acife_1477	ENOG4108UZ3	Transporter
Acife_1478	ENOG4105YVS	arsR family transcriptional regulator
Acife_1479	ENOG4105D29	Helix-turn-helix type 11 domain protein
Acife_1485	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Acife_1492	ENOG4105JAB	phenazine biosynthesis protein, phzf family
Acife_1494	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Acife_1496	ENOG4105XMH	SpoVT AbrB domain protein
Acife_1499	ENOG4105CAF	HipA N-terminal domain protein
Acife_1501	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Acife_1502	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Acife_1503	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Acife_1505	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Acife_1506	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Acife_1508	ENOG4105K8N	protein family UPF0079, ATPase
Acife_1509	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Acife_1510	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Acife_1511	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Acife_1512	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Acife_1515	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Acife_1516	ENOG4105CUT	histidyl-tRNA synthetase
Acife_1518	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Acife_1519	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Acife_1529	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Acife_1532	ENOG4108UXE	Protein tyrosine phosphatase
Acife_1546	ENOG4105C26	Dehydrogenase
Acife_1568	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
Acife_1572	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
Acife_1574	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
Acife_1578	ENOG4107R3N	Filamentation induced by cAMP protein fic
Acife_1579	ENOG4105BZU	Histidine kinase
Acife_1587	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
Acife_1588	ENOG4105EJG	cellulose synthase
Acife_1590	ENOG4105E39	Enoyl-CoA hydratase
Acife_1591	ENOG4105BZU	Histidine kinase
Acife_1592	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Acife_1594	ENOG4107QZ7	Cellulose synthase catalytic subunit
Acife_1595	ENOG4107EEX	Cellulose synthase regulator protein
Acife_1598	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
Acife_1599	ENOG4105BZU	Histidine kinase
Acife_1602	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Acife_1603	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Acife_1605	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Acife_1606	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Acife_1610	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Acife_1611	ENOG4108IAB	Phoh family
Acife_1612	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
Acife_1617	ENOG4105NZG	Ferredoxin
Acife_1618	ENOG41090P5	ferredoxin-like protein
Acife_1620	ENOG4105C10	Electron transfer flavoprotein
Acife_1621	ENOG4105BZJ	Electron transfer flavoprotein
Acife_1627	ENOG4105VQD	rieske 2fe-2S domain-containing protein
Acife_1630	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Acife_1632	ENOG410605C	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
Acife_1634	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Acife_1635	ENOG4105C3J	Cysteine desulfurase
Acife_1636	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
Acife_1637	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
Acife_1639	ENOG4105PS4	nifq family
Acife_1641	ENOG4105X87	nitrogen fixation
Acife_1642	ENOG4108VQE	nitrogen fixation protein
Acife_1643	ENOG4108UR2	Nitrogen fixation protein NifX
Acife_1644	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
Acife_1645	ENOG4105D0B	Nitrogenase protein alpha chain
Acife_1647	ENOG4105U82	Ferredoxin
Acife_1648	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
Acife_1650	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
Acife_1652	ENOG4108K8Z	nad( )--dinitrogen-reductase ADP-d-ribosyltransferase
Acife_1653	ENOG41065RQ	ADP-ribosylation crystallin J1
Acife_1654	ENOG4108JUA	Transcriptional regulator
Acife_1655	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
Acife_1656	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
Acife_1657	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Acife_1660	ENOG4108QWQ	LRV FeS4 cluster domain protein
Acife_1661	ENOG4105XV5	nifz family
Acife_1663	ENOG4105C3J	Cysteine desulfurase
Acife_1666	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Acife_1667	ENOG4108ZIT	Ferredoxin, 2FE-2S
Acife_1671	ENOG4107XWS	modD protein
Acife_1672	ENOG4105C26	Dehydrogenase
Acife_1677	ENOG4107STW	synthase
Acife_1678	ENOG4105Q84	sucrose synthase
Acife_1682	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Acife_1685	ENOG4105EW9	transcriptional regulator AsnC family
Acife_1686	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Acife_1691	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
Acife_1692	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Acife_1693	ENOG4107QTZ	amino acid
Acife_1695	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Acife_1696	ENOG41080RH	Thioredoxin
Acife_1698	ENOG4105EU0	Major facilitator Superfamily
Acife_1699	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Acife_1700	ENOG4105CTB	Polyprenyl synthetase
Acife_1701	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Acife_1702	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Acife_1703	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Acife_1705	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Acife_1706	ENOG4105BZF	Glycosyl transferase (Group 1
Acife_1707	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Acife_1709	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
Acife_1720	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Acife_1722	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
Acife_1728	ENOG4105KAV	tspo and mbr like protein
Acife_1732	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
Acife_1741	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Acife_1742	ENOG4105MA0	exported protein
Acife_1743	ENOG4105CFU	surface antigen
Acife_1750	ENOG4107UWP	Major facilitator superfamily MFS_1
Acife_1751	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Acife_1752	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Acife_1753	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Acife_1754	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Acife_1755	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Acife_1756	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
Acife_1757	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
Acife_1758	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Acife_1759	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Acife_1761	ENOG4105C3F	Signal peptidase i
Acife_1762	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Acife_1763	ENOG4105C0H	protease
Acife_1765	ENOG4105EMN	RNA polymerase sigma factor
Acife_1766	ENOG4108IYU	L-aspartate oxidase
Acife_1768	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
Acife_1771	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Acife_1772	ENOG4105F8V	Hydrolase, tatD family
Acife_1773	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Acife_1776	ENOG4105IPI	Membrane
Acife_1777	ENOG4105DB7	PHP domain protein
Acife_1779	ENOG4105D3R	alkyl hydroperoxide reductase
Acife_1780	ENOG4108Z4U	Ferredoxin
Acife_1781	ENOG4105BZ1	(ABC) transporter
Acife_1782	ENOG4105F8C	transglutaminase domain-containing protein
Acife_1784	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Acife_1785	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Acife_1786	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Acife_1787	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Acife_1788	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Acife_1789	ENOG4108VPT	UPF0234 protein
Acife_1790	ENOG4108ZAF	Molybdopterin
Acife_1791	ENOG4105M00	molybdopterin converting factor, subunit 1
Acife_1792	ENOG4105ERU	peptidase
Acife_1794	ENOG4105M08	Membrane
Acife_1797	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
Acife_1801	ENOG4107QN2	dihydrolipoyl dehydrogenase
Acife_1803	ENOG4106CJB	Phospholipase Carboxylesterase
Acife_1804	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Acife_1805	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Acife_1812	ENOG4105C5H	ABC transporter
Acife_1814	ENOG4106ECQ	phosphomannomutase
Acife_1815	ENOG4105C0D	helicase
Acife_1823	ENOG4105C45	hydrogenase expression formation protein (HypE)
Acife_1827	ENOG4107RSS	Hydrogenase accessory protein HypB
Acife_1828	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
Acife_1830	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Acife_1831	ENOG4105Y3E	Modulates RecA activity (By similarity)
Acife_1832	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Acife_1833	ENOG4108I62	cina-like protein
Acife_1834	ENOG4108ZAI	phosphatidylglycerophosphatase a
Acife_1835	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Acife_1836	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
Acife_1837	ENOG4105PW4	Sugar fermentation stimulation protein homolog
Acife_1838	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Acife_1839	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Acife_1840	ENOG41075W9	High frequency lysogenization protein HflD homolog
Acife_1849	ENOG4105CRE	cytochrome C
Acife_1850	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
Acife_1857	ENOG4105TX3	Histidine kinase
Acife_1858	ENOG4108UYB	regulatoR
Acife_1861	ENOG4107RDB	Major Facilitator
Acife_1862	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Acife_1869	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
Acife_1871	ENOG41090Y2	cytochrome C
Acife_1873	ENOG4105M08	Membrane
Acife_1875	ENOG4105EVH	UPF0753 protein
Acife_1876	ENOG4108TWJ	NADH dehydrogenase subunit 5
Acife_1880	ENOG4105EKE	dihydroorotase
Acife_1881	ENOG4105C01	Dihydroxy-acid dehydratase
Acife_1883	ENOG4108YK4	Acid-resistance membrane protein
Acife_1886	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
Acife_1891	ENOG4107QJE	Chromosome Partitioning Protein
Acife_1912	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Acife_1919	ENOG4105C2M	dna polymerase I
Acife_1930	ENOG4105C4K	Nad synthetase
Acife_1949	ENOG4107QMH	DNA methylase
Acife_1953	ENOG4105C0D	helicase
Acife_1954	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Acife_1956	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Acife_1961	ENOG4105K70	DNA-binding protein
Acife_1964	ENOG4105C26	Dehydrogenase
Acife_1971	ENOG4105D7V	transposase
Acife_1981	ENOG4105E5H	Transposase
Acife_1993	ENOG4105GTN	ParB Domain Protein Nuclease
Acife_1995	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
Acife_1998	ENOG4105K4H	Nlp p60 protein
Acife_2000	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Acife_2001	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Acife_2002	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Acife_2004	ENOG4105CHM	Aminotransferase
Acife_2005	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Acife_2006	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Acife_2009	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Acife_2010	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Acife_2012	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Acife_2013	ENOG4105C54	Major Facilitator superfamily
Acife_2014	ENOG4107QYA	phosphate
Acife_2015	ENOG4105DE4	1-phosphofructokinase
Acife_2027	ENOG4105FE9	pseudouridine synthase
Acife_2028	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
Acife_2029	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Acife_2030	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Acife_2031	ENOG4105C31	Tryptophanyl-tRNA synthetase
Acife_2032	ENOG4108Z4T	Peptidase M50
Acife_2033	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
Acife_2037	ENOG4105EGS	Mechanosensitive ion channel
Acife_2038	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Acife_2039	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Acife_2040	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Acife_2042	ENOG4105DJ0	Poly(A) Polymerase
Acife_2044	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Acife_2046	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Acife_2047	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Acife_2048	ENOG4105CQB	FAD linked oxidase domain protein
Acife_2050	ENOG4105C98	muts2 protein
Acife_2053	ENOG4108MN8	Membrane
Acife_2062	ENOG4105DND	Transcriptional regulator
Acife_2065	ENOG4105CW7	secretion protein, HlyD family
Acife_2066	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
Acife_2070	ENOG4108UR0	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Acife_2071	ENOG4105K78	MarR family Transcriptional regulator
Acife_2072	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Acife_2076	ENOG4108IFG	nitrite reductase, (NAD(P)H)
Acife_2077	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
Acife_2078	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Acife_2079	ENOG4108MTB	glycosyl transferase family
Acife_2080	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Acife_2087	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Acife_2088	ENOG4105BZU	Histidine kinase
Acife_2095	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Acife_2099	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Acife_2118	ENOG4105CMQ	Chloride channel
Acife_2119	ENOG41082AG	Plasmid maintenance system antidote protein
Acife_2122	ENOG4105E4C	Lytic transglycosylase catalytic
Acife_2124	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Acife_2125	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Acife_2127	ENOG4105BZS	acriflavin resistance protein
Acife_2130	ENOG4105DHQ	Histidine kinase
Acife_2131	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Acife_2147	ENOG4108IJF	Heavy metal efflux pump, CzcA
Acife_2149	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Acife_2150	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Acife_2151	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Acife_2152	ENOG4108ZP8	Acetolactate synthase small subunit
Acife_2153	ENOG4105C7K	acetolactate synthase
Acife_2154	ENOG4105C98	muts2 protein
Acife_2157	ENOG4108Z6B	deaminase
Acife_2162	ENOG4105E4G	Type IV pilus
Acife_2163	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Acife_2164	ENOG4105D49	3-dehydroquinate synthase
Acife_2165	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Acife_2166	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Acife_2167	ENOG4105CBC	glutamate synthase
Acife_2168	ENOG4105BZ8	glutamate synthase
Acife_2169	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Acife_2170	ENOG4108Z20	Acyl-transferase
Acife_2175	ENOG4105C7B	Threonine dehydratase
Acife_2182	ENOG4105F5P	DNA-damage-inducible protein d
Acife_2185	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Acife_2186	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Acife_2187	ENOG4105VIE	preprotein translocase, subunit YajC
Acife_2188	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Acife_2189	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Acife_2190	ENOG4105C37	(CBS) domain
Acife_2192	ENOG4105C28	cystathionine
Acife_2193	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Acife_2195	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Acife_2196	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Acife_2197	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Acife_2198	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Acife_2199	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Acife_2200	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Acife_2202	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Acife_2203	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Acife_2205	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Acife_2206	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
Acife_2207	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Acife_2208	ENOG4105N82	Endonuclease
Acife_2211	ENOG4105NBF	ammecr1 domain protein
Acife_2212	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
Acife_2217	ENOG4105C02	permease
Acife_2218	ENOG4105C1Q	protoporphyrinogen oxidase
Acife_2220	ENOG4105CB5	ATP-dependent DNA helicase recG
Acife_2222	ENOG4105KME	endoribonuclease L-psp
Acife_2223	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Acife_2224	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Acife_2225	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Acife_2226	ENOG4105DSJ	YicC domain protein
Acife_2229	ENOG4105FAE	von Willebrand factor, type A
Acife_2231	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
Acife_2232	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
Acife_2236	ENOG4105CJ1	ABC, transporter
Acife_2237	ENOG4107QWP	ABC-2 type transporter
Acife_2238	ENOG4107QWP	ABC-2 type transporter
Acife_2239	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Acife_2246	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
Acife_2250	ENOG4106H3A	restriction
Acife_2257	ENOG4105K4U	addiction module toxin, RelE StbE family
Acife_2258	ENOG4105DZR	Type I site-specific deoxyribonuclease
Acife_2263	ENOG4105DFG	type I secretion outer membrane protein
Acife_2264	ENOG4105CJR	Integral membrane protein (MviN
Acife_2266	ENOG4105DTN	riboflavin biosynthesis protein ribF
Acife_2267	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Acife_2268	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Acife_2272	ENOG4105CQ0	ABC transporter
Acife_2276	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Acife_2277	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Acife_2279	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Acife_2282	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Acife_2283	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Acife_2286	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Acife_2287	ENOG4107RIQ	Sulfate adenylate transferase
Acife_2292	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
Acife_2294	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Acife_2295	ENOG4107QPD	alcohol dehydrogenase
Acife_2300	ENOG4105EKQ	RNA-directed DNA polymerase
Acife_2301	ENOG4105J1P	transposase, IS3 IS911 family protein
Acife_2308	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Acife_2309	ENOG41076CZ	activating enzyme
Acife_2314	ENOG4105F5W	AtP-binding protein
Acife_2323	ENOG4105EKQ	RNA-directed DNA polymerase
Acife_2337	ENOG4105DQ4	alcohol dehydrogenase
Acife_2343	ENOG4105EQR	Transposase IS116 IS110 IS902
Acife_2346	ENOG4108R85	Short chain dehydrogenase
Acife_2347	ENOG4105DVW	rieske (2Fe-2S)
Acife_2348	ENOG4105EQR	Transposase IS116 IS110 IS902
Acife_2355	ENOG4108DMA	Nad-dependent epimerase dehydratase
Acife_2356	ENOG4105E3J	oxidoreductase
Acife_2359	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
Acife_2360	ENOG4105ETS	cytosine purines uracil thiamine allantoin
Acife_2361	ENOG4105EQR	Transposase IS116 IS110 IS902
Acife_2366	ENOG4105EYH	Exonuclease
Acife_2367	ENOG4107RH8	nuclease SbcCD subunit D
Acife_2372	ENOG4105MUN	Divergent AAA domain
Acife_2382	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acife_2383	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Acife_2384	ENOG4105C98	muts2 protein
Acife_2386	ENOG4105VCC	30S ribosomal protein S21
Acife_2387	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acife_2388	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Acife_2389	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Acife_2392	ENOG4105CSA	Coproporphyrinogen iii oxidase
Acife_2395	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Acife_2396	ENOG4105DZ1	carboxypeptidase
Acife_2404	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
Acife_2406	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Acife_2407	ENOG4105C8V	SAICAR synthetase
Acife_2410	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Acife_2411	ENOG4108UT2	hemolysin iii
Acife_2412	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Acife_2414	ENOG4105VW4	glutaredoxin 3
Acife_2415	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Acife_2418	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Acife_2421	ENOG41080HT	Transcriptional regulator, arsr family
Acife_2422	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Acife_2425	ENOG4105CUZ	uba thif-type nad fad binding protein
Acife_2426	ENOG4105EYA	deoxyribonuclease
Acife_2427	ENOG4105D0A	hydroxylase
Acife_2428	ENOG4105D0A	hydroxylase
Acife_2429	ENOG4105W0Z	cytoplasmic protein
Acife_2430	ENOG4105C0P	Mg chelatase subunit ChlI
Acife_2433	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Acife_2435	ENOG41072GX	Peptidase M22 Glycoprotease
Acife_2436	ENOG4105DVT	helicase
Acife_2440	ENOG4105K4H	Nlp p60 protein
Acife_2445	ENOG4105CE1	Ferrous iron transport protein b
Acife_2448	ENOG4108Z86	Glutamine amidotransferase
Acife_2449	ENOG4105DQR	SNARE associated Golgi
Acife_2452	ENOG4105DUM	transcriptional regulator, lysR family
Acife_2455	ENOG4105DGU	Histone deacetylase
Acife_2456	ENOG4105FAE	von Willebrand factor, type A
Acife_2465	ENOG4107QZT	geranylgeranyl reductase
Acife_2466	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
Acife_2468	ENOG4105PHD	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Acife_2470	ENOG4105RQ5	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Acife_2471	ENOG41086B8	CoB-CoM heterodisulfide reductase
Acife_2474	ENOG4105EWK	phytoene
Acife_2477	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
Acife_2478	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
Acife_2479	ENOG41082J7	Rhodanese domain protein
Acife_2480	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Acife_2482	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Acife_2483	ENOG4105DB1	molybdopterin oxidoreductase
Acife_2485	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Acife_2487	ENOG4105BZU	Histidine kinase
Acife_2488	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Acife_2493	ENOG4105UUH	Domain of unknown function DUF302 
Acife_2494	ENOG4105CGH	5'-nucleotidase
Acife_2495	ENOG4105DFF	Rod shape-determining protein mreb
Acife_2496	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
Acife_2499	ENOG4105CNI	cell division protein FtsW
Acife_2500	ENOG4105DZ1	carboxypeptidase
Acife_2502	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Acife_2503	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Acife_2504	ENOG4107S90	membrAne
Acife_2514	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Acife_2515	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
Acife_2516	ENOG4107RIS	Acyl-transferase
Acife_2517	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Acife_2521	ENOG41090A4	Pterin carbinolamine dehydratase
Acife_2522	ENOG4105WPN	DNA integration recombination invertion protein
Acife_2526	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Acife_2533	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Acife_2534	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Acife_2535	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Acife_2536	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Acife_2537	ENOG41082NX	50s ribosomal protein l35
Acife_2538	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Acife_2539	ENOG4105C22	threonyL-tRNA synthetase
Acife_2541	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acife_2542	ENOG4105C8S	subunit m
Acife_2544	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acife_2545	ENOG4105DF2	NADH dehydrogenase subunit j
Acife_2546	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acife_2547	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Acife_2549	ENOG4107QIZ	NADH dehydrogenase
Acife_2551	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acife_2552	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Acife_2553	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acife_2554	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Acife_2556	ENOG4105CP7	Triose-phosphate isomerase
Acife_2557	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Acife_2558	ENOG4105EEI	dihydropteroate synthase
Acife_2559	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Acife_2560	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Acife_2561	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Acife_2562	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Acife_2584	ENOG4108Q5Y	Membrane
Acife_2595	ENOG4107R3R	Cytochrome o ubiquinol oxidase subunit III
Acife_2596	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Acife_2597	ENOG4105E2S	oxidase) subunit II
Acife_2602	ENOG4105DZG	Dehydrogenase
Acife_2608	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Acife_2615	ENOG4105CVK	Glutamate decarboxylase
Acife_2616	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Acife_2621	ENOG4105EQR	Transposase IS116 IS110 IS902
Acife_2625	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
Acife_2626	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
Acife_2629	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
Acife_2630	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Acife_2635	ENOG4105CFH	Aspartokinase
Acife_2636	ENOG4105C8Y	Acetylornithine aminotransferase
Acife_2637	ENOG4105DBV	ornithine carbamoyltransferase
Acife_2638	ENOG4105CDH	Citrulline--aspartate ligase
Acife_2641	ENOG4107RZZ	dna polymerase iii epsilon subunit
Acife_2642	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Acife_2644	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Acife_2646	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Acife_2647	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Acife_2648	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Acife_2649	ENOG41082KD	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Acife_2650	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Acife_2651	ENOG4105CHV	Transcription elongation factor NusA
Acife_2652	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Acife_2653	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
Acife_2655	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Acife_2656	ENOG4105D1H	recombination factor protein RarA
Acife_2658	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
Acife_2659	ENOG4105CNU	cell division protein FtsK
Acife_2660	ENOG4105C3M	thioredoxin reductase
Acife_2663	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Acife_2664	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Acife_2665	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Acife_2666	ENOG4108JA2	transcriptioN-repair coupling factor
Acife_2669	ENOG4105EAC	phosphoserine phosphatase
Acife_2670	ENOG4105EHV	domain protein
Acife_2671	ENOG4105DC8	reductase
Acife_2672	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
Acife_2673	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Acife_2677	ENOG410841Q	phosphoesterase PA-phosphatase related protein
Acife_2679	ENOG4105W5Q	DNA repair protein (RadC
Acife_2681	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Acife_2682	ENOG4108ZT0	50S ribosomal protein l17
Acife_2683	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Acife_2684	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Acife_2685	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Acife_2686	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Acife_2687	ENOG41067V7	50S ribosomal protein L36
Acife_2688	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Acife_2689	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Acife_2690	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Acife_2691	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Acife_2692	ENOG41084RK	50S ribosomal protein L30
Acife_2693	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Acife_2694	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Acife_2695	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Acife_2696	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Acife_2697	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Acife_2698	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Acife_2699	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Acife_2700	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Acife_2701	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Acife_2703	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Acife_2705	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Acife_2706	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Acife_2707	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Acife_2708	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Acife_2709	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Acife_2710	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Acife_2711	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Acife_2712	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Acife_2713	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Acife_2714	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Acife_2715	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Acife_2716	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Acife_2717	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Acife_2718	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Acife_2719	ENOG4108VZM	50s ribosomal protein L10
Acife_2720	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Acife_2721	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Acife_2722	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Acife_2724	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Acife_2726	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
Acife_2731	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Acife_2732	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Acife_2734	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Acife_2735	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Acife_2736	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Acife_2738	ENOG4105DWV	Homoserine O-trans-acetylase
Acife_2739	ENOG4105DWV	Homoserine O-trans-acetylase
Acife_2741	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Acife_2742	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Acife_2744	ENOG4105CHH	sulfate transporter
Acife_2745	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Acife_2746	ENOG4105K46	50S ribosomal protein l27
Acife_2747	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Acife_2748	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Acife_2749	ENOG41090R7	Ferric uptake
Acife_2750	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Acife_2751	ENOG4108Z1B	Cyclase dehydrase
Acife_2752	ENOG4105DZQ	phospholipase D Transphosphatidylase
Acife_2753	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Acife_2757	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Acife_2758	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Acife_2759	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Acife_2762	ENOG4105CZX	twitching motility protein
Acife_2763	ENOG4105CZX	twitching motility protein
Acife_2764	ENOG4105DFA	alanine racemase domain protein
Acife_2765	ENOG4105II7	pyrroline-5-carboxylate reductase
Acife_2766	ENOG4108VIA	integral membrane protein
Acife_2767	ENOG4105VZ9	UPF0235 protein
Acife_2768	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Acife_2770	ENOG4105CW7	secretion protein, HlyD family
Acife_2771	ENOG4105CAS	nag kinase
Acife_2772	ENOG4105R8C	Transcriptional regulator
Acife_2776	ENOG4108EX3	reductase
Acife_2777	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
Acife_2778	ENOG4105C4B	ABC transporter, permease
Acife_2779	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
Acife_2780	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
Acife_2782	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
Acife_2783	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Acife_2785	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Acife_2786	ENOG4105MJ2	Competence protein
Acife_2787	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Acife_2788	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
Acife_2789	ENOG4105C87	Aminotransferase class I and II
Acife_2790	ENOG4105D1S	lipid A biosynthesis
Acife_2791	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Acife_2793	ENOG4105D16	lipopolysaccharide heptosyltransferase i
Acife_2794	ENOG4106WTF	Glycosyl transferase, family 2
Acife_2798	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Acife_2799	ENOG4107BJW	polysaccharide deacetylase
Acife_2800	ENOG4105CKK	Glycosyl transferase, family 2
Acife_2801	ENOG4105M6F	mutator MutT protein
Acife_2802	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Acife_2803	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Acife_2805	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Acife_2806	ENOG4107MKT	Stringent starvation protein a
Acife_2807	ENOG4108IQE	Amp-dependent synthetase and ligase
Acife_2808	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Acife_2810	ENOG4108V6E	Cell division protein mraZ
Acife_2811	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Acife_2813	ENOG4105CJN	penicillin-binding protein
Acife_2814	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Acife_2815	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
Acife_2816	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Acife_2817	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Acife_2818	ENOG4105CNI	cell division protein FtsW
Acife_2819	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Acife_2820	ENOG4105DFU	Cell wall formation (By similarity)
Acife_2821	ENOG4105D4A	Cell wall formation (By similarity)
Acife_2822	ENOG4105CPF	Cell wall formation (By similarity)
Acife_2823	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
Acife_2824	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Acife_2825	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Acife_2828	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Acife_2829	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Acife_2830	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Acife_2831	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Acife_2833	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
Acife_2834	ENOG4105E4C	Lytic transglycosylase catalytic
Acife_2835	ENOG4105KB2	stringent starvation protein b
Acife_2843	ENOG4105C2D	reductase
Acife_2852	ENOG4105CEY	Amp-dependent synthetase and ligase
Acife_2855	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Acife_2856	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
Acife_2857	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Acife_2859	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Acife_2860	ENOG4107TUY	Histidine kinase
Acife_2861	ENOG4107QHF	type ii secretion system protein e
Acife_2862	ENOG4105E2X	shikimate dehydrogenase
Acife_2863	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
Acife_2864	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Acife_2865	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Acife_2867	ENOG4108U78	Glutathione S-transferase
Acife_2868	ENOG4105D6S	protein involved in catabolism of external DNA
Acife_2870	ENOG4105CGK	Exodeoxyribonuclease III
Acife_2871	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
Acife_2872	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Acife_2873	ENOG4105EGS	Mechanosensitive ion channel
Acife_2874	ENOG4105C75	arginyL-tRNA synthetase
Acife_2877	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Acife_2879	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Acife_2880	ENOG41082I2	s4 domain protein
Acife_2881	ENOG4105DA5	(ABC) transporter
Acife_2884	ENOG4107PE3	Mammalian cell entry related domain protein
Acife_2885	ENOG4105CY3	ABC transporter, permease
Acife_2886	ENOG4105DHJ	ABC, transporter
Acife_2887	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Acife_2888	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Acife_2890	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Acife_2892	ENOG4107WP9	Histidine kinase
Acife_2893	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
Acife_2894	ENOG4105CEN	a g-specific adenine glycosylase
Acife_2896	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Acife_2899	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Acife_2900	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
Acife_2901	ENOG4105DM4	PTS System
Acife_2902	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
Acife_2903	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acife_2904	ENOG4108IUZ	ABC transporter
Acife_2905	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
Acife_2907	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Acife_2908	ENOG4105C2X	Arabinose 5-phosphate isomerase
Acife_2911	ENOG4108S0S	Nucleotidyl transferase
Acife_2912	ENOG4105EHM	Aminoglycoside phosphotransferase
Acife_2913	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
Acife_2914	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Acife_2915	ENOG4105E3A	(ABC) transporter
Acife_2918	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Acife_2919	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Acife_2920	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Acife_2921	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Acife_2922	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Acife_2923	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Acife_2924	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Acife_2925	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Acife_2926	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Acife_2927	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Acife_2928	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
Acife_2929	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Acife_2930	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Acife_2932	ENOG4105VEQ	Cold shock protein
Acife_2934	ENOG4105BZU	Histidine kinase
Acife_2935	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Acife_2939	ENOG4105CD3	dihydroorotase
Acife_2940	ENOG4105CXT	aspartate transcarbamylase
Acife_2941	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Acife_2942	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Acife_2943	ENOG4108UJU	UPF0301 protein
Acife_2949	ENOG4108KQ5	Integrase catalytic subunit
Acife_2957	ENOG41082VC	UPF0145 protein
Acife_2959	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
Acife_2967	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
Acife_2968	ENOG4105VGJ	Virulence-associated protein
Acife_2988	ENOG4108UUM	single-stranded DNA-binding protein
Acife_2990	ENOG4108IYH	Dna topoisomerase
Acife_2993	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
Acife_2998	ENOG4108Z4T	Peptidase M50
Acife_3007	ENOG4105K70	DNA-binding protein
Acife_3010	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Acife_3034	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
Acife_3035	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
Acife_3045	ENOG4107QHF	type ii secretion system protein e
Acife_3076	ENOG4105D7Z	glutathione synthase
Acife_3078	ENOG4105BZN	citrate synthase
Acife_3079	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Acife_3080	ENOG4107QN2	dihydrolipoyl dehydrogenase
Acife_3085	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Acife_3086	ENOG4108UJD	30S ribosomal protein S9
Acife_3087	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Acife_3091	ENOG4105CBX	hi0933 family
Acife_3092	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Acife_3093	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
Acife_3095	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Acife_3097	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Acife_3098	ENOG4107SVH	Potassium channel protein
Acife_3099	ENOG4105C2M	dna polymerase I
Acife_3102	ENOG4105CUV	Homoserine Kinase
Acife_3103	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
Acife_3104	ENOG4105C4R	Atp-dependent dna helicase
Acife_3108	ENOG4105DCG	PHP domain protein
Acife_3109	ENOG4105DWV	Homoserine O-trans-acetylase
Acife_3120	ENOG4105D29	Helix-turn-helix type 11 domain protein
Acife_3123	ENOG4105M18	-acetyltransferase
Acife_3128	ENOG4105D65	subunit l
Acife_3131	ENOG4105D2N	Aldolase
Acife_3132	ENOG4105FAE	von Willebrand factor, type A
Acife_3135	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
Acife_3137	ENOG4108UQY	Iron-storage protein
Acife_3138	ENOG4105KNY	Microcompartments protein
Acife_3139	ENOG4105KNY	Microcompartments protein
Acife_3141	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Acife_3144	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
Acife_3145	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
Acife_3149	ENOG4107RDB	Major Facilitator
Acife_3152	ENOG4105DUM	transcriptional regulator, lysR family
Acife_3156	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
Acife_3158	ENOG4105BZU	Histidine kinase
Acife_3177	ENOG4107SCA	Formamidase (EC 3.5.1.49)
Acife_3184	ENOG4108ZF3	Phosphatase
Acife_3187	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Acife_3188	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Acife_3189	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Acife_3190	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Acife_3191	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Acife_3192	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Acife_3193	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Acife_3194	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Acife_3195	ENOG41082T0	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Acife_3196	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
Acife_3198	ENOG4105FA0	parb-like partition protein
Acife_3199	ENOG4107QJE	Chromosome Partitioning Protein
Acife_3200	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Acife_3201	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Acife_3204	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Acife_3210	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Acife_3211	ENOG4105EU8	FAD linked oxidase domain protein
Acife_3212	ENOG4105CQB	FAD linked oxidase domain protein
Acife_3218	ENOG4108TJN	glycosyl transferase group 1
Acife_3222	ENOG4105E5H	Transposase
Acife_3224	ENOG4105EKQ	RNA-directed DNA polymerase
Acife_3228	ENOG4105CMR	udp-glucose 4-epimerase
Acife_3236	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
Acife_3240	ENOG4105MFV	ABC-2 type transporter
Acife_3250	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Acife_3251	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Acife_3252	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Acife_3253	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
Acife_3254	ENOG4105C54	Major Facilitator superfamily
Acife_3256	ENOG4105D52	delta-aminolevulinic acid dehydratase
Acife_3258	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Acife_3260	ENOG4107ZUX	Histidine triad (HIT) protein
Acife_3261	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Acife_3262	ENOG4107S5G	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Acife_3263	ENOG4105DWF	phosphomethylpyrimidine kinase
Acife_3267	ENOG4105EIX	cytochrome c1
Acife_3268	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Acife_3269	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Acife_3270	ENOG4105CHR	reductase
Acife_3271	ENOG4106RE7	Cytochrome
Acife_3274	ENOG4105XPQ	lipid carrier protein
Acife_3275	ENOG4105CFP	Peptidase U32