AFE_1686 8daba46c3869f1d5ba62d867f91505ed 88 TIGRFAM TIGR02704 carboxysome_B: carboxysome peptide B 1 80 1.9E-46 T 12-10-2018 IPR014077 Carboxysome peptide B AFE_1686 8daba46c3869f1d5ba62d867f91505ed 88 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 77 6.0E-19 T 12-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml AFE_1686 8daba46c3869f1d5ba62d867f91505ed 88 SUPERFAMILY SSF159133 1 84 8.63E-25 T 12-10-2018 IPR036677 EutN/Ccml superfamily AFE_1686 8daba46c3869f1d5ba62d867f91505ed 88 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 10 80 1.0E-33 T 12-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml AFE_1686 8daba46c3869f1d5ba62d867f91505ed 88 Gene3D G3DSA:2.40.50.220 1 86 2.2E-27 T 12-10-2018 IPR036677 EutN/Ccml superfamily AFE_0665 d6a0efbaa9a27bafd857289fc9168163 103 Gene3D G3DSA:3.30.300.90 1 91 3.1E-26 T 12-10-2018 AFE_0665 d6a0efbaa9a27bafd857289fc9168163 103 SUPERFAMILY SSF82657 3 89 6.15E-23 T 12-10-2018 IPR036065 BolA-like superfamily AFE_0665 d6a0efbaa9a27bafd857289fc9168163 103 PIRSF PIRSF003113 1 99 4.7E-23 T 12-10-2018 IPR002634 BolA protein AFE_0665 d6a0efbaa9a27bafd857289fc9168163 103 Pfam PF01722 BolA-like protein 10 84 4.1E-24 T 12-10-2018 IPR002634 BolA protein AFE_0063 d5133fabb4f5d203132a8eb3838cc112 140 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 12 124 3.2E-32 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 AFE_0063 d5133fabb4f5d203132a8eb3838cc112 140 Gene3D G3DSA:3.10.129.10 5 135 3.7E-38 T 12-10-2018 AFE_0063 d5133fabb4f5d203132a8eb3838cc112 140 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 9 132 9.9E-50 T 12-10-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 AFE_0063 d5133fabb4f5d203132a8eb3838cc112 140 Pfam PF03061 Thioesterase superfamily 22 107 4.5E-15 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFE_0063 d5133fabb4f5d203132a8eb3838cc112 140 SUPERFAMILY SSF54637 8 134 4.84E-38 T 12-10-2018 IPR029069 HotDog domain superfamily AFE_0063 d5133fabb4f5d203132a8eb3838cc112 140 PIRSF PIRSF003230 1 139 1.6E-42 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 AFE_0063 d5133fabb4f5d203132a8eb3838cc112 140 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 13 30 - T 12-10-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 AFE_2074 79e9ba9ae773d363e2b4cf98e23c771e 340 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 5 336 37.092 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFE_2074 79e9ba9ae773d363e2b4cf98e23c771e 340 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 121 7.2E-32 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFE_2074 79e9ba9ae773d363e2b4cf98e23c771e 340 PIRSF PIRSF000148 5 340 3.8E-131 T 12-10-2018 AFE_2074 79e9ba9ae773d363e2b4cf98e23c771e 340 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 142 322 7.8E-56 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFE_2074 79e9ba9ae773d363e2b4cf98e23c771e 340 SUPERFAMILY SSF55347 132 323 1.7E-72 T 12-10-2018 AFE_2074 79e9ba9ae773d363e2b4cf98e23c771e 340 Gene3D G3DSA:3.30.360.10 131 319 1.9E-141 T 12-10-2018 AFE_2074 79e9ba9ae773d363e2b4cf98e23c771e 340 Gene3D G3DSA:3.40.50.720 8 334 1.9E-141 T 12-10-2018 AFE_2074 79e9ba9ae773d363e2b4cf98e23c771e 340 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 337 1.9E-136 T 12-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFE_2074 79e9ba9ae773d363e2b4cf98e23c771e 340 SMART SM00859 7 122 2.9E-43 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFE_2074 79e9ba9ae773d363e2b4cf98e23c771e 340 SUPERFAMILY SSF51735 6 160 4.19E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1518 64890ca7a830ea289d2305d1851d98de 114 Gene3D G3DSA:3.10.20.30 1 114 9.6E-22 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_1518 64890ca7a830ea289d2305d1851d98de 114 SUPERFAMILY SSF54292 5 106 3.67E-11 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFE_1518 64890ca7a830ea289d2305d1851d98de 114 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFE_1518 64890ca7a830ea289d2305d1851d98de 114 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 22 104 6.4E-9 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFE_1479 c8ee7a2a5c819f8f9ae911153d648f22 364 PIRSF PIRSF000089 25 358 2.1E-110 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 AFE_1479 c8ee7a2a5c819f8f9ae911153d648f22 364 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 234 316 1.0E-35 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 AFE_1479 c8ee7a2a5c819f8f9ae911153d648f22 364 Gene3D G3DSA:3.40.50.620 25 228 7.3E-63 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_1479 c8ee7a2a5c819f8f9ae911153d648f22 364 Gene3D G3DSA:3.40.50.1220 229 362 4.2E-53 T 12-10-2018 AFE_1479 c8ee7a2a5c819f8f9ae911153d648f22 364 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 297 323 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 AFE_1479 c8ee7a2a5c819f8f9ae911153d648f22 364 Pfam PF01012 Electron transfer flavoprotein domain 29 204 3.0E-37 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFE_1479 c8ee7a2a5c819f8f9ae911153d648f22 364 SUPERFAMILY SSF52402 27 227 3.14E-48 T 12-10-2018 AFE_1479 c8ee7a2a5c819f8f9ae911153d648f22 364 SMART SM00893 29 221 3.3E-38 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFE_1479 c8ee7a2a5c819f8f9ae911153d648f22 364 SUPERFAMILY SSF52467 234 352 6.0E-46 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFE_0492 cc897e77489fcae8a311343f6dc4be78 173 Gene3D G3DSA:3.90.80.10 1 173 1.9E-68 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFE_0492 cc897e77489fcae8a311343f6dc4be78 173 Pfam PF00719 Inorganic pyrophosphatase 18 172 2.2E-55 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFE_0492 cc897e77489fcae8a311343f6dc4be78 173 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 173 36.853 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFE_0492 cc897e77489fcae8a311343f6dc4be78 173 SUPERFAMILY SSF50324 4 172 3.66E-66 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFE_1960 72b555bab937f793c6bee2bb23e7b605 500 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 63 473 3.5E-61 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_1960 72b555bab937f793c6bee2bb23e7b605 500 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 47 492 2.3E-76 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_1960 72b555bab937f793c6bee2bb23e7b605 500 Gene3D G3DSA:3.40.710.10 271 495 1.7E-46 T 12-10-2018 AFE_1960 72b555bab937f793c6bee2bb23e7b605 500 Gene3D G3DSA:3.40.710.10 38 101 9.8E-6 T 12-10-2018 AFE_1960 72b555bab937f793c6bee2bb23e7b605 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 375 389 3.0E-12 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_1960 72b555bab937f793c6bee2bb23e7b605 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 451 464 3.0E-12 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_1960 72b555bab937f793c6bee2bb23e7b605 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 72 91 3.0E-12 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_1960 72b555bab937f793c6bee2bb23e7b605 500 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 390 404 3.0E-12 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_1960 72b555bab937f793c6bee2bb23e7b605 500 Gene3D G3DSA:3.50.80.20 102 190 3.1E-8 T 12-10-2018 AFE_1960 72b555bab937f793c6bee2bb23e7b605 500 SUPERFAMILY SSF56601 41 494 4.16E-69 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_2759 0b317ced627c4d58378879c10be3a0f7 288 Gene3D G3DSA:1.10.8.10 14 97 2.7E-17 T 12-10-2018 AFE_2759 0b317ced627c4d58378879c10be3a0f7 288 SUPERFAMILY SSF53335 19 282 2.22E-51 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2759 0b317ced627c4d58378879c10be3a0f7 288 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 194 200 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFE_2759 0b317ced627c4d58378879c10be3a0f7 288 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 25 285 2.4E-63 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 AFE_2759 0b317ced627c4d58378879c10be3a0f7 288 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 15 287 39.323 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 AFE_2759 0b317ced627c4d58378879c10be3a0f7 288 Gene3D G3DSA:3.40.50.150 98 287 5.0E-51 T 12-10-2018 AFE_2759 0b317ced627c4d58378879c10be3a0f7 288 Pfam PF05175 Methyltransferase small domain 116 204 5.7E-13 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 AFE_2759 0b317ced627c4d58378879c10be3a0f7 288 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 36 283 8.4E-77 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 AFE_3120 618524b316a76a69b0fdc59d2e8cd684 104 PIRSF PIRSF019883 1 99 2.7E-24 T 12-10-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane AFE_3120 618524b316a76a69b0fdc59d2e8cd684 104 Pfam PF10993 Protein of unknown function (DUF2818) 7 97 7.5E-34 T 12-10-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane AFE_0057 1d543498dc1556fc2777fbe34d68a3a3 360 Hamap MF_00569 Quinolinate synthase A [nadA]. 10 359 48.121 T 12-10-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFE_0057 1d543498dc1556fc2777fbe34d68a3a3 360 Gene3D G3DSA:3.40.50.10800 99 357 5.5E-82 T 12-10-2018 AFE_0057 1d543498dc1556fc2777fbe34d68a3a3 360 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 13 360 2.8E-91 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFE_0057 1d543498dc1556fc2777fbe34d68a3a3 360 Pfam PF02445 Quinolinate synthetase A protein 17 358 9.4E-105 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFE_0057 1d543498dc1556fc2777fbe34d68a3a3 360 Gene3D G3DSA:3.40.50.10800 18 340 5.5E-82 T 12-10-2018 AFE_0057 1d543498dc1556fc2777fbe34d68a3a3 360 SUPERFAMILY SSF142754 22 358 6.41E-95 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFE_0057 1d543498dc1556fc2777fbe34d68a3a3 360 Gene3D G3DSA:3.40.50.10800 220 310 5.5E-82 T 12-10-2018 AFE_2112 78cd284b960dd5cee764f9f75a8bedec 95 SUPERFAMILY SSF141000 3 93 3.53E-24 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 AFE_2112 78cd284b960dd5cee764f9f75a8bedec 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 20.955 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFE_2112 78cd284b960dd5cee764f9f75a8bedec 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 90 4.9E-15 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFE_2112 78cd284b960dd5cee764f9f75a8bedec 95 Gene3D G3DSA:1.10.20.60 1 93 5.0E-20 T 12-10-2018 AFE_2112 78cd284b960dd5cee764f9f75a8bedec 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 9.8E-24 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 Gene3D G3DSA:2.40.30.10 91 189 1.4E-22 T 12-10-2018 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 SUPERFAMILY SSF52343 195 324 1.2E-34 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 Gene3D G3DSA:3.10.20.30 1 90 2.8E-17 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 SUPERFAMILY SSF54292 3 88 1.07E-18 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 Pfam PF00175 Oxidoreductase NAD-binding domain 204 304 5.3E-18 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 SUPERFAMILY SSF63380 97 191 6.45E-21 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 Pfam PF00970 Oxidoreductase FAD-binding domain 101 191 2.4E-9 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 61 1.0E-7 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 239 250 9.7E-10 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 291 299 9.7E-10 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 227 236 9.7E-10 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 142 149 9.7E-10 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 202 221 9.7E-10 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 PRINTS PR00410 Phenol hydroxylase reductase family signature 202 221 3.7E-18 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 PRINTS PR00410 Phenol hydroxylase reductase family signature 291 299 3.7E-18 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 PRINTS PR00410 Phenol hydroxylase reductase family signature 124 136 3.7E-18 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 PRINTS PR00410 Phenol hydroxylase reductase family signature 227 236 3.7E-18 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_0860 504d006b700b0c926a8c487d6f72a3c8 327 Gene3D G3DSA:3.40.50.80 191 327 3.3E-31 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFE_1613 e1d0738d70c80a414a1b85f093ba8ea8 190 Pfam PF13470 PIN domain 7 114 8.8E-12 T 12-10-2018 IPR002716 PIN domain AFE_0329 1e175e523ae679ceb2bc85551c4f4288 97 Pfam PF00276 Ribosomal protein L23 9 93 7.0E-33 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AFE_0329 1e175e523ae679ceb2bc85551c4f4288 97 Gene3D G3DSA:3.30.70.330 1 96 2.1E-34 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily AFE_0329 1e175e523ae679ceb2bc85551c4f4288 97 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 97 21.705 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AFE_0329 1e175e523ae679ceb2bc85551c4f4288 97 SUPERFAMILY SSF54189 2 92 5.4E-31 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0870 59c4e4fdac6846c13542855bd31e6932 87 Gene3D G3DSA:3.30.2310.20 2 86 1.3E-11 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFE_0870 59c4e4fdac6846c13542855bd31e6932 87 SUPERFAMILY SSF143011 2 87 9.16E-19 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFE_0870 59c4e4fdac6846c13542855bd31e6932 87 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 7 86 7.1E-26 T 12-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 AFE_0870 59c4e4fdac6846c13542855bd31e6932 87 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 25 86 3.6E-9 T 12-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 AFE_2348 deb13dafd3fcb2a21e0cefc675dee768 264 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 117 131 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFE_2348 deb13dafd3fcb2a21e0cefc675dee768 264 SUPERFAMILY SSF55174 20 86 4.71E-8 T 12-10-2018 AFE_2348 deb13dafd3fcb2a21e0cefc675dee768 264 Pfam PF00849 RNA pseudouridylate synthase 81 212 1.4E-18 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2348 deb13dafd3fcb2a21e0cefc675dee768 264 Pfam PF01479 S4 domain 22 57 4.1E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_2348 deb13dafd3fcb2a21e0cefc675dee768 264 Gene3D G3DSA:3.30.70.580 83 239 1.3E-47 T 12-10-2018 AFE_2348 deb13dafd3fcb2a21e0cefc675dee768 264 Gene3D G3DSA:3.10.290.10 21 76 2.8E-10 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFE_2348 deb13dafd3fcb2a21e0cefc675dee768 264 SUPERFAMILY SSF55120 68 252 1.23E-39 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2348 deb13dafd3fcb2a21e0cefc675dee768 264 Gene3D G3DSA:3.30.70.1560 141 231 1.3E-47 T 12-10-2018 AFE_2348 deb13dafd3fcb2a21e0cefc675dee768 264 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 85 242 1.4E-41 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFE_2617 50e32c8eaf5be86a15d307b5571f5fb3 481 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 469 4.2E-145 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AFE_2617 50e32c8eaf5be86a15d307b5571f5fb3 481 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 7.6E-8 T 12-10-2018 AFE_2617 50e32c8eaf5be86a15d307b5571f5fb3 481 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 72 97 7.6E-8 T 12-10-2018 AFE_2617 50e32c8eaf5be86a15d307b5571f5fb3 481 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 215 236 7.6E-8 T 12-10-2018 AFE_2617 50e32c8eaf5be86a15d307b5571f5fb3 481 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 307 319 7.6E-8 T 12-10-2018 AFE_2617 50e32c8eaf5be86a15d307b5571f5fb3 481 Pfam PF00361 Proton-conducting membrane transporter 126 418 5.8E-79 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2617 50e32c8eaf5be86a15d307b5571f5fb3 481 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 470 18.652 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AFE_1743 c0552db0f581126163f9609ff6f59fb1 123 PIRSF PIRSF009151 1 123 2.3E-46 T 12-10-2018 IPR008497 Protein of unknown function DUF779 AFE_1743 c0552db0f581126163f9609ff6f59fb1 123 Pfam PF05610 Protein of unknown function (DUF779) 15 109 2.6E-40 T 12-10-2018 IPR008497 Protein of unknown function DUF779 AFE_2988 fc019bd9cfe650f2e2bb4bb6ae457a86 336 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2988 fc019bd9cfe650f2e2bb4bb6ae457a86 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 321 2.3E-24 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFE_2988 fc019bd9cfe650f2e2bb4bb6ae457a86 336 Pfam PF00005 ABC transporter 32 184 1.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2988 fc019bd9cfe650f2e2bb4bb6ae457a86 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 301 8.2E-15 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFE_2988 fc019bd9cfe650f2e2bb4bb6ae457a86 336 SUPERFAMILY SSF52540 5 254 2.13E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2988 fc019bd9cfe650f2e2bb4bb6ae457a86 336 SMART SM00382 41 233 3.7E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2988 fc019bd9cfe650f2e2bb4bb6ae457a86 336 Gene3D G3DSA:3.40.50.300 2 330 1.4E-97 T 12-10-2018 AFE_0428 10cea04a0ff8c938d0601449b96b8736 549 TIGRFAM TIGR00552 nadE: NAD+ synthetase 271 514 5.6E-58 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 AFE_0428 10cea04a0ff8c938d0601449b96b8736 549 SUPERFAMILY SSF56317 1 242 9.68E-57 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFE_0428 10cea04a0ff8c938d0601449b96b8736 549 Pfam PF02540 NAD synthase 267 512 2.0E-70 T 12-10-2018 IPR022310 NAD/GMP synthase AFE_0428 10cea04a0ff8c938d0601449b96b8736 549 Gene3D G3DSA:3.60.110.10 1 263 2.8E-90 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFE_0428 10cea04a0ff8c938d0601449b96b8736 549 PIRSF PIRSF006630 1 539 1.4E-191 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFE_0428 10cea04a0ff8c938d0601449b96b8736 549 Pfam PF00795 Carbon-nitrogen hydrolase 2 243 1.4E-21 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFE_0428 10cea04a0ff8c938d0601449b96b8736 549 Gene3D G3DSA:3.40.50.620 264 539 6.5E-113 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0428 10cea04a0ff8c938d0601449b96b8736 549 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 1 537 29.534 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFE_0428 10cea04a0ff8c938d0601449b96b8736 549 SUPERFAMILY SSF52402 260 519 1.01E-72 T 12-10-2018 AFE_2859 ece6da3a1f5576ca9e46db48c169a8d9 118 SUPERFAMILY SSF46785 5 98 1.06E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2859 ece6da3a1f5576ca9e46db48c169a8d9 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 2.7E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2859 ece6da3a1f5576ca9e46db48c169a8d9 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 2.7E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2859 ece6da3a1f5576ca9e46db48c169a8d9 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 2.7E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2859 ece6da3a1f5576ca9e46db48c169a8d9 118 Pfam PF12840 Helix-turn-helix domain 13 73 1.3E-15 T 12-10-2018 AFE_2859 ece6da3a1f5576ca9e46db48c169a8d9 118 Gene3D G3DSA:1.10.10.10 3 97 5.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2859 ece6da3a1f5576ca9e46db48c169a8d9 118 SMART SM00418 12 92 1.1E-15 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 376 2.4E-75 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 93 2.5E-14 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 SUPERFAMILY SSF50615 11 95 1.59E-26 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 513 51.736 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 PIRSF PIRSF039088 2 514 2.6E-235 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 SUPERFAMILY SSF47917 384 511 1.15E-45 T 12-10-2018 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 Gene3D G3DSA:1.20.150.20 384 514 1.4E-47 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 SUPERFAMILY SSF52540 96 382 2.27E-95 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 Gene3D G3DSA:3.40.50.300 95 383 2.9E-132 T 12-10-2018 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 Gene3D G3DSA:2.40.30.20 2 94 4.8E-30 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 1.5E-46 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3205 957037e45da9e2bd567ca452a1abfe56 514 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 4 511 1.2E-251 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3051 501fc629a89fb7e1caff18798a9e62c8 473 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 16 137 6.2E-45 T 12-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_3051 501fc629a89fb7e1caff18798a9e62c8 473 SUPERFAMILY SSF51649 143 469 1.83E-145 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_3051 501fc629a89fb7e1caff18798a9e62c8 473 Gene3D G3DSA:3.20.20.110 143 473 1.1E-155 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_3051 501fc629a89fb7e1caff18798a9e62c8 473 Hamap MF_01338 Ribulose bisphosphate carboxylase large chain [rbcL]. 2 468 60.328 T 12-10-2018 IPR020888 Ribulose bisphosphate carboxylase large subunit, type I GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_3051 501fc629a89fb7e1caff18798a9e62c8 473 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 189 197 - T 12-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_3051 501fc629a89fb7e1caff18798a9e62c8 473 Gene3D G3DSA:3.30.70.150 15 141 2.6E-50 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_3051 501fc629a89fb7e1caff18798a9e62c8 473 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 147 455 6.0E-133 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_3051 501fc629a89fb7e1caff18798a9e62c8 473 SUPERFAMILY SSF54966 5 141 3.66E-57 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 Gene3D G3DSA:2.30.130.40 1 108 1.4E-33 T 12-10-2018 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 348 367 6.2E-55 T 12-10-2018 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 587 603 6.2E-55 T 12-10-2018 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 665 684 6.2E-55 T 12-10-2018 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 718 736 6.2E-55 T 12-10-2018 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 695 714 6.2E-55 T 12-10-2018 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 PIRSF PIRSF001174 1 767 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 562 764 9.6E-96 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 344 480 2.0E-17 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 SMART SM00382 340 484 2.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 Gene3D G3DSA:1.20.58.1480 112 235 2.8E-45 T 12-10-2018 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 Gene3D G3DSA:3.40.50.300 305 482 5.2E-60 T 12-10-2018 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 Hamap MF_01973 Lon protease [lon]. 2 764 71.211 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 SUPERFAMILY SSF54211 587 762 4.55E-57 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 TIGRFAM TIGR00763 lon: endopeptidase La 3 762 1.2E-300 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 2 192 1.9E-43 T 12-10-2018 IPR003111 Lon, substrate-binding domain AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 SUPERFAMILY SSF52540 305 580 6.79E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 Gene3D G3DSA:1.10.8.60 483 576 2.9E-33 T 12-10-2018 AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 SUPERFAMILY SSF88697 2 192 5.47E-50 T 12-10-2018 IPR015947 PUA-like superfamily AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 SMART SM00464 1 193 2.5E-76 T 12-10-2018 IPR003111 Lon, substrate-binding domain AFE_0912 4e8c64afc54037d3fdd52d4b9acfa330 796 Gene3D G3DSA:3.30.230.10 577 764 1.8E-80 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_0372 6db968dc76bb2a07ed408527839325d9 362 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 5 351 24.849 T 12-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0372 6db968dc76bb2a07ed408527839325d9 362 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 9 169 1.9E-38 T 12-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0372 6db968dc76bb2a07ed408527839325d9 362 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 185 342 5.0E-12 T 12-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0372 6db968dc76bb2a07ed408527839325d9 362 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 77 90 - T 12-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 AFE_0372 6db968dc76bb2a07ed408527839325d9 362 Gene3D G3DSA:3.30.2350.20 18 345 7.6E-107 T 12-10-2018 AFE_0372 6db968dc76bb2a07ed408527839325d9 362 Gene3D G3DSA:3.30.2340.10 168 310 7.6E-107 T 12-10-2018 AFE_0372 6db968dc76bb2a07ed408527839325d9 362 SUPERFAMILY SSF55120 14 348 2.73E-83 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 SUPERFAMILY SSF53623 97 309 2.49E-48 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 Gene3D G3DSA:3.90.190.20 314 448 5.8E-25 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 360 3.1E-9 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 446 1.1E-198 T 12-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 SUPERFAMILY SSF51984 1 88 1.7E-20 T 12-10-2018 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 Gene3D G3DSA:3.40.50.720 1 90 7.6E-33 T 12-10-2018 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 Pfam PF01225 Mur ligase family, catalytic domain 2 97 1.4E-15 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 Gene3D G3DSA:3.40.1190.10 91 313 4.2E-54 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 447 58.024 T 12-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 SUPERFAMILY SSF53244 310 446 4.97E-34 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_0645 fda9979c21595f6b2a72f5cfc72c7d5e 455 Pfam PF08245 Mur ligase middle domain 108 291 2.3E-18 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 SUPERFAMILY SSF82714 714 797 3.4E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 Gene3D G3DSA:3.30.2090.10 182 273 6.0E-251 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 SUPERFAMILY SSF82866 800 1032 8.63E-43 T 12-10-2018 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 Gene3D G3DSA:3.30.70.1430 559 662 6.0E-251 T 12-10-2018 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 SUPERFAMILY SSF82693 138 325 1.31E-18 T 12-10-2018 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 Gene3D G3DSA:3.30.2090.10 714 802 6.0E-251 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 Gene3D G3DSA:3.30.70.1430 42 810 6.0E-251 T 12-10-2018 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 SUPERFAMILY SSF82693 42 127 1.67E-20 T 12-10-2018 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 Pfam PF00873 AcrB/AcrD/AcrF family 12 1027 1.0E-221 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 2.8E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 2.8E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 PRINTS PR00702 Acriflavin resistance protein family signature 443 466 2.8E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.8E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 2.8E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 PRINTS PR00702 Acriflavin resistance protein family signature 542 559 2.8E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 2.8E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 PRINTS PR00702 Acriflavin resistance protein family signature 468 491 2.8E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 Gene3D G3DSA:3.30.70.1440 663 861 6.0E-251 T 12-10-2018 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 Gene3D G3DSA:1.20.1640.10 506 1025 6.0E-251 T 12-10-2018 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 Gene3D G3DSA:3.30.70.1320 135 327 6.0E-251 T 12-10-2018 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 SUPERFAMILY SSF82714 186 268 6.54E-16 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 SUPERFAMILY SSF82866 293 496 9.81E-40 T 12-10-2018 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1032 0.0 T 12-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 AFE_1947 20d05fe91fb80e6874e12b533b07d9e4 1036 Gene3D G3DSA:1.20.1640.10 16 505 6.0E-251 T 12-10-2018 AFE_0847 48dfd8dde7bdcf46cde981bde5f5f7f5 545 SUPERFAMILY SSF52540 1 267 2.59E-118 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0847 48dfd8dde7bdcf46cde981bde5f5f7f5 545 Gene3D G3DSA:3.40.50.300 1 283 8.8E-126 T 12-10-2018 AFE_0847 48dfd8dde7bdcf46cde981bde5f5f7f5 545 Pfam PF06418 CTP synthase N-terminus 3 265 9.3E-121 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFE_0847 48dfd8dde7bdcf46cde981bde5f5f7f5 545 Hamap MF_01227 CTP synthase [pyrG]. 2 539 50.238 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFE_0847 48dfd8dde7bdcf46cde981bde5f5f7f5 545 TIGRFAM TIGR00337 PyrG: CTP synthase 2 534 4.3E-235 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFE_0847 48dfd8dde7bdcf46cde981bde5f5f7f5 545 Gene3D G3DSA:3.40.50.880 285 543 2.0E-96 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_0847 48dfd8dde7bdcf46cde981bde5f5f7f5 545 Pfam PF00117 Glutamine amidotransferase class-I 300 533 3.0E-52 T 12-10-2018 IPR017926 Glutamine amidotransferase AFE_0847 48dfd8dde7bdcf46cde981bde5f5f7f5 545 SUPERFAMILY SSF52317 288 540 2.6E-80 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_2344 511d35cb54a3c3c58937638d686e961a 164 Pfam PF00027 Cyclic nucleotide-binding domain 39 121 2.5E-14 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFE_2344 511d35cb54a3c3c58937638d686e961a 164 Gene3D G3DSA:2.60.120.10 7 149 5.7E-25 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_2344 511d35cb54a3c3c58937638d686e961a 164 SUPERFAMILY SSF51206 11 136 7.46E-25 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFE_2344 511d35cb54a3c3c58937638d686e961a 164 SMART SM00100 18 137 1.3E-7 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFE_0134 2b72ef8fb37497894c28d768a620c4a7 463 PIRSF PIRSF000167 8 463 2.9E-160 T 12-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 AFE_0134 2b72ef8fb37497894c28d768a620c4a7 463 SMART SM00729 57 280 3.3E-47 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFE_0134 2b72ef8fb37497894c28d768a620c4a7 463 Gene3D G3DSA:3.80.30.20 5 371 8.5E-115 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFE_0134 2b72ef8fb37497894c28d768a620c4a7 463 Gene3D G3DSA:1.10.10.920 372 463 2.4E-30 T 12-10-2018 AFE_0134 2b72ef8fb37497894c28d768a620c4a7 463 Pfam PF04055 Radical SAM superfamily 63 236 7.5E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_0134 2b72ef8fb37497894c28d768a620c4a7 463 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 11 463 2.1E-177 T 12-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 AFE_0134 2b72ef8fb37497894c28d768a620c4a7 463 Pfam PF06969 HemN C-terminal domain 374 439 1.9E-12 T 12-10-2018 IPR010723 HemN, C-terminal AFE_0134 2b72ef8fb37497894c28d768a620c4a7 463 SUPERFAMILY SSF102114 10 452 7.59E-132 T 12-10-2018 AFE_1674 4ecb13f546e2a86fd395a918c3c3dbcf 328 SUPERFAMILY SSF55821 9 204 1.4E-66 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFE_1674 4ecb13f546e2a86fd395a918c3c3dbcf 328 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 10 203 1.2E-60 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFE_1674 4ecb13f546e2a86fd395a918c3c3dbcf 328 Pfam PF03481 Putative GTP-binding controlling metal-binding 194 321 2.7E-20 T 12-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain AFE_1674 4ecb13f546e2a86fd395a918c3c3dbcf 328 Pfam PF01300 Telomere recombination 16 192 2.6E-58 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFE_1674 4ecb13f546e2a86fd395a918c3c3dbcf 328 Gene3D G3DSA:3.40.50.11030 209 327 6.5E-18 T 12-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily AFE_1674 4ecb13f546e2a86fd395a918c3c3dbcf 328 Gene3D G3DSA:3.90.870.10 2 208 3.8E-84 T 12-10-2018 AFE_1674 4ecb13f546e2a86fd395a918c3c3dbcf 328 PIRSF PIRSF004930 2 326 1.5E-106 T 12-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 AFE_2400 1ee6298c4059cd80b68f5ce536332e69 286 SUPERFAMILY SSF53098 173 281 6.2E-16 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_2400 1ee6298c4059cd80b68f5ce536332e69 286 Gene3D G3DSA:3.30.420.10 176 282 4.1E-12 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_2400 1ee6298c4059cd80b68f5ce536332e69 286 Pfam PF00665 Integrase core domain 178 281 1.7E-13 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 Gene3D G3DSA:1.25.40.10 7 127 8.4E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 Gene3D G3DSA:1.25.40.10 168 292 4.5E-43 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 Pfam PF08238 Sel1 repeat 59 93 3.4E-6 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 Pfam PF08238 Sel1 repeat 241 276 1.8E-8 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 Pfam PF08238 Sel1 repeat 28 57 0.12 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 Pfam PF08238 Sel1 repeat 205 240 3.6E-11 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 Pfam PF08238 Sel1 repeat 172 204 9.6E-10 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 SMART SM00671 205 240 1.4E-10 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 SMART SM00671 169 204 3.1E-8 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 SMART SM00671 26 57 22.0 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 SMART SM00671 241 276 8.9E-10 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 SMART SM00671 58 93 2.1E-8 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 SUPERFAMILY SSF81901 12 101 1.44E-18 T 12-10-2018 AFE_0117 2cfc283dea42fc0a243ab0c9c21ced18 294 SUPERFAMILY SSF81901 172 284 5.75E-37 T 12-10-2018 AFE_3032 358d801bb8d77718caf9172876e73b63 229 Pfam PF00483 Nucleotidyl transferase 8 135 4.1E-15 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFE_3032 358d801bb8d77718caf9172876e73b63 229 SUPERFAMILY SSF53448 7 222 4.96E-50 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_3032 358d801bb8d77718caf9172876e73b63 229 Gene3D G3DSA:3.90.550.10 7 224 1.0E-52 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2342 5d9a64347f30c080903910f63cb94676 285 Gene3D G3DSA:1.10.10.10 205 281 7.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2342 5d9a64347f30c080903910f63cb94676 285 SUPERFAMILY SSF88659 201 280 4.11E-20 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFE_2342 5d9a64347f30c080903910f63cb94676 285 Pfam PF04542 Sigma-70 region 2 61 127 2.0E-19 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFE_2342 5d9a64347f30c080903910f63cb94676 285 Pfam PF04545 Sigma-70, region 4 224 276 1.3E-16 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFE_2342 5d9a64347f30c080903910f63cb94676 285 PRINTS PR00046 Major sigma-70 factor signature 109 117 2.5E-21 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2342 5d9a64347f30c080903910f63cb94676 285 PRINTS PR00046 Major sigma-70 factor signature 263 274 2.5E-21 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2342 5d9a64347f30c080903910f63cb94676 285 PRINTS PR00046 Major sigma-70 factor signature 248 263 2.5E-21 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2342 5d9a64347f30c080903910f63cb94676 285 PRINTS PR00046 Major sigma-70 factor signature 227 239 2.5E-21 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2342 5d9a64347f30c080903910f63cb94676 285 PRINTS PR00046 Major sigma-70 factor signature 85 98 2.5E-21 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2342 5d9a64347f30c080903910f63cb94676 285 SUPERFAMILY SSF88946 36 127 8.63E-33 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFE_2342 5d9a64347f30c080903910f63cb94676 285 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 57 278 5.0E-34 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFE_2342 5d9a64347f30c080903910f63cb94676 285 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 85 98 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2342 5d9a64347f30c080903910f63cb94676 285 Gene3D G3DSA:1.20.120.1810 27 129 1.0E-30 T 12-10-2018 AFE_0882 689821c4793748b651807d051a9283e1 387 Gene3D G3DSA:3.50.50.60 1 116 7.0E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0882 689821c4793748b651807d051a9283e1 387 Pfam PF01593 Flavin containing amine oxidoreductase 124 367 8.9E-22 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFE_0882 689821c4793748b651807d051a9283e1 387 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 90 2.2E-15 T 12-10-2018 AFE_0882 689821c4793748b651807d051a9283e1 387 SUPERFAMILY SSF51905 1 366 1.79E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0882 689821c4793748b651807d051a9283e1 387 Gene3D G3DSA:3.50.50.60 117 375 8.3E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0882 689821c4793748b651807d051a9283e1 387 SUPERFAMILY SSF54373 216 315 4.12E-23 T 12-10-2018 AFE_0192 89aebc72588bbfbfb46f09209ae7a1e4 221 Pfam PF13511 Domain of unknown function (DUF4124) 9 59 9.2E-7 T 12-10-2018 IPR025392 Domain of unknown function DUF4124 AFE_0192 89aebc72588bbfbfb46f09209ae7a1e4 221 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 91 119 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 AFE_0192 89aebc72588bbfbfb46f09209ae7a1e4 221 Gene3D G3DSA:1.10.530.10 36 197 4.4E-42 T 12-10-2018 AFE_0192 89aebc72588bbfbfb46f09209ae7a1e4 221 Pfam PF01464 Transglycosylase SLT domain 73 169 2.6E-25 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 AFE_0192 89aebc72588bbfbfb46f09209ae7a1e4 221 SUPERFAMILY SSF53955 52 195 1.13E-41 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFE_2389 9efa3834cf107bcea812136f8d569c4b 395 Pfam PF01494 FAD binding domain 8 344 1.4E-23 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFE_2389 9efa3834cf107bcea812136f8d569c4b 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 141 156 2.9E-12 T 12-10-2018 AFE_2389 9efa3834cf107bcea812136f8d569c4b 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 2.9E-12 T 12-10-2018 AFE_2389 9efa3834cf107bcea812136f8d569c4b 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 2.9E-12 T 12-10-2018 AFE_2389 9efa3834cf107bcea812136f8d569c4b 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.9E-12 T 12-10-2018 AFE_2389 9efa3834cf107bcea812136f8d569c4b 395 SUPERFAMILY SSF51905 7 389 3.28E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2389 9efa3834cf107bcea812136f8d569c4b 395 Gene3D G3DSA:3.50.50.60 8 342 1.1E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2389 9efa3834cf107bcea812136f8d569c4b 395 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 8 394 2.0E-106 T 12-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 AFE_2389 9efa3834cf107bcea812136f8d569c4b 395 Gene3D G3DSA:3.30.9.50 79 273 1.1E-87 T 12-10-2018 AFE_1520 27ea9421a2894eacabfc3fb357bf6640 519 SUPERFAMILY SSF53807 3 518 5.56E-171 T 12-10-2018 AFE_1520 27ea9421a2894eacabfc3fb357bf6640 519 Gene3D G3DSA:3.40.50.1980 368 480 6.6E-86 T 12-10-2018 AFE_1520 27ea9421a2894eacabfc3fb357bf6640 519 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 88 95 - T 12-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 AFE_1520 27ea9421a2894eacabfc3fb357bf6640 519 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 70 496 1.9E-114 T 12-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 AFE_1520 27ea9421a2894eacabfc3fb357bf6640 519 Gene3D G3DSA:3.40.50.1980 70 211 7.5E-44 T 12-10-2018 AFE_1520 27ea9421a2894eacabfc3fb357bf6640 519 TIGRFAM TIGR01286 nifK: nitrogenase molybdenum-iron protein beta chain 2 519 2.3E-259 T 12-10-2018 IPR005976 Nitrogenase molybdenum-iron protein beta chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 AFE_1520 27ea9421a2894eacabfc3fb357bf6640 519 Pfam PF11844 Domain of unknown function (DUF3364) 1 56 3.5E-27 T 12-10-2018 IPR024564 Nitrogenase molybdenum-iron protein beta chain, N-terminal KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 AFE_1520 27ea9421a2894eacabfc3fb357bf6640 519 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 151 165 - T 12-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 AFE_1520 27ea9421a2894eacabfc3fb357bf6640 519 Gene3D G3DSA:3.40.50.1980 222 323 5.6E-31 T 12-10-2018 AFE_1520 27ea9421a2894eacabfc3fb357bf6640 519 Gene3D G3DSA:1.20.89.10 324 519 6.6E-86 T 12-10-2018 AFE_2867 d206de8607110c0e72bf8e79175974f6 87 Pfam PF13192 Thioredoxin domain 8 82 6.5E-13 T 12-10-2018 IPR012336 Thioredoxin-like fold AFE_2867 d206de8607110c0e72bf8e79175974f6 87 Gene3D G3DSA:3.40.30.10 1 86 8.3E-14 T 12-10-2018 AFE_2867 d206de8607110c0e72bf8e79175974f6 87 SUPERFAMILY SSF52833 6 85 6.69E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_2022 5342c1e4bb221c25ae6af2cd5dd1354b 393 Pfam PF00155 Aminotransferase class I and II 33 387 3.6E-67 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFE_2022 5342c1e4bb221c25ae6af2cd5dd1354b 393 Gene3D G3DSA:3.40.640.10 64 287 1.1E-127 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_2022 5342c1e4bb221c25ae6af2cd5dd1354b 393 SUPERFAMILY SSF53383 4 392 1.93E-110 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_2022 5342c1e4bb221c25ae6af2cd5dd1354b 393 Gene3D G3DSA:3.90.1150.10 27 387 1.1E-127 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_2022 5342c1e4bb221c25ae6af2cd5dd1354b 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFE_1819 61b25a4e212993ec8e5818750d97c073 382 SUPERFAMILY SSF55031 181 290 2.84E-27 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFE_1819 61b25a4e212993ec8e5818750d97c073 382 Gene3D G3DSA:3.30.70.360 181 294 1.0E-126 T 12-10-2018 AFE_1819 61b25a4e212993ec8e5818750d97c073 382 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 99 137 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AFE_1819 61b25a4e212993ec8e5818750d97c073 382 SUPERFAMILY SSF53187 4 376 6.81E-66 T 12-10-2018 AFE_1819 61b25a4e212993ec8e5818750d97c073 382 Gene3D G3DSA:3.40.630.10 9 364 1.0E-126 T 12-10-2018 AFE_1819 61b25a4e212993ec8e5818750d97c073 382 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 7 375 1.4E-164 T 12-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 AFE_1819 61b25a4e212993ec8e5818750d97c073 382 Pfam PF07687 Peptidase dimerisation domain 177 282 3.1E-23 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain AFE_1819 61b25a4e212993ec8e5818750d97c073 382 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 4 377 52.225 T 12-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 AFE_1819 61b25a4e212993ec8e5818750d97c073 382 Pfam PF01546 Peptidase family M20/M25/M40 64 372 1.9E-41 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 Pfam PF05697 Bacterial trigger factor protein (TF) 8 148 3.3E-35 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 SUPERFAMILY SSF54534 138 253 5.3E-27 T 12-10-2018 AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 SUPERFAMILY SSF109998 254 423 1.57E-36 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 Gene3D G3DSA:1.10.3120.10 129 412 1.1E-78 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 SUPERFAMILY SSF102735 8 124 1.57E-30 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 269 408 1.6E-24 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 Hamap MF_00303 Trigger factor [tig]. 8 413 18.623 T 12-10-2018 IPR005215 Trigger factor GO:0015031 AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 163 235 1.4E-11 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 PIRSF PIRSF003095 8 427 2.6E-105 T 12-10-2018 IPR005215 Trigger factor GO:0015031 AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 TIGRFAM TIGR00115 tig: trigger factor 18 407 1.1E-115 T 12-10-2018 IPR005215 Trigger factor GO:0015031 AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 Gene3D G3DSA:3.30.70.1050 5 122 2.3E-33 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 AFE_0909 c20b9cb3464b50699d2ce330b54f0d9c 434 Gene3D G3DSA:3.10.50.40 156 252 1.1E-78 T 12-10-2018 AFE_3209 29098b56f21debaa22b69c4292b8ad87 249 Gene3D G3DSA:1.20.120.220 77 249 2.8E-50 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3209 29098b56f21debaa22b69c4292b8ad87 249 SUPERFAMILY SSF81336 81 241 1.96E-39 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3209 29098b56f21debaa22b69c4292b8ad87 249 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 19 242 5.2E-39 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3209 29098b56f21debaa22b69c4292b8ad87 249 ProSitePatterns PS00449 ATP synthase a subunit signature. 184 193 - T 12-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3209 29098b56f21debaa22b69c4292b8ad87 249 Hamap MF_01393 ATP synthase subunit a [atpB]. 6 248 14.411 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3209 29098b56f21debaa22b69c4292b8ad87 249 Pfam PF00119 ATP synthase A chain 28 241 3.3E-50 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3209 29098b56f21debaa22b69c4292b8ad87 249 PRINTS PR00123 ATP synthase A subunit signature 181 203 1.3E-16 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3209 29098b56f21debaa22b69c4292b8ad87 249 PRINTS PR00123 ATP synthase A subunit signature 228 243 1.3E-16 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3209 29098b56f21debaa22b69c4292b8ad87 249 PRINTS PR00123 ATP synthase A subunit signature 85 101 1.3E-16 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3209 29098b56f21debaa22b69c4292b8ad87 249 PRINTS PR00123 ATP synthase A subunit signature 161 176 1.3E-16 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_0649 4ba4e25cd7e45fd8321070873b42a9c8 250 SUPERFAMILY SSF56219 1 241 4.58E-33 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFE_0649 4ba4e25cd7e45fd8321070873b42a9c8 250 Gene3D G3DSA:3.60.10.10 1 244 4.1E-39 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFE_0649 4ba4e25cd7e45fd8321070873b42a9c8 250 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 3 230 2.9E-12 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFE_0292 7d3171d0fc364df3b295e13af4223e32 201 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 4 195 6.4E-81 T 12-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 AFE_0292 7d3171d0fc364df3b295e13af4223e32 201 Pfam PF07021 Methionine biosynthesis protein MetW 4 195 1.3E-80 T 12-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 AFE_0292 7d3171d0fc364df3b295e13af4223e32 201 SUPERFAMILY SSF53335 5 173 6.41E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0292 7d3171d0fc364df3b295e13af4223e32 201 Gene3D G3DSA:3.40.50.150 2 186 1.2E-23 T 12-10-2018 AFE_1692 757e0b1638723712e81a1d02c6261c41 332 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 32 91 2.3E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_1692 757e0b1638723712e81a1d02c6261c41 332 Gene3D G3DSA:3.40.190.10 192 293 4.9E-43 T 12-10-2018 AFE_1692 757e0b1638723712e81a1d02c6261c41 332 Gene3D G3DSA:1.10.10.10 30 117 1.5E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1692 757e0b1638723712e81a1d02c6261c41 332 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 68 79 1.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_1692 757e0b1638723712e81a1d02c6261c41 332 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 1.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_1692 757e0b1638723712e81a1d02c6261c41 332 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 58 68 1.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_1692 757e0b1638723712e81a1d02c6261c41 332 SUPERFAMILY SSF46785 27 110 9.54E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1692 757e0b1638723712e81a1d02c6261c41 332 SUPERFAMILY SSF53850 119 322 3.8E-46 T 12-10-2018 AFE_1692 757e0b1638723712e81a1d02c6261c41 332 Gene3D G3DSA:3.40.190.10 120 314 4.9E-43 T 12-10-2018 AFE_1692 757e0b1638723712e81a1d02c6261c41 332 Pfam PF03466 LysR substrate binding domain 117 318 1.1E-51 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 SUPERFAMILY SSF88697 281 371 1.31E-19 T 12-10-2018 IPR015947 PUA-like superfamily AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 1.3E-48 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 PRINTS PR00474 Glutamate 5-kinase family signature 120 141 1.3E-48 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 PRINTS PR00474 Glutamate 5-kinase family signature 46 60 1.3E-48 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 PRINTS PR00474 Glutamate 5-kinase family signature 80 108 1.3E-48 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 PRINTS PR00474 Glutamate 5-kinase family signature 213 233 1.3E-48 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 SMART SM00359 281 355 1.6E-8 T 12-10-2018 IPR002478 PUA domain GO:0003723 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 ProSitePatterns PS00902 Glutamate 5-kinase signature. 211 228 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 PIRSF PIRSF000729 4 373 8.6E-125 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 Pfam PF00696 Amino acid kinase family 10 233 1.1E-44 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 Gene3D G3DSA:2.30.130.10 270 372 3.7E-28 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 Gene3D G3DSA:3.40.1160.10 1 269 6.5E-91 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 Pfam PF01472 PUA domain 281 340 5.2E-15 T 12-10-2018 IPR002478 PUA domain GO:0003723 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 SUPERFAMILY SSF53633 9 261 1.44E-69 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 Hamap MF_00456 Glutamate 5-kinase [proB]. 9 263 35.817 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_0281 65d9f10e7084ffdce995326bba69e1de 376 TIGRFAM TIGR01027 proB: glutamate 5-kinase 10 370 1.2E-121 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 PIRSF PIRSF001365 1 290 1.7E-90 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 1.9E-33 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 1.9E-33 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 1.9E-33 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 1.9E-33 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 286 1.1E-107 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 Pfam PF00701 Dihydrodipicolinate synthetase family 2 286 9.5E-97 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 SUPERFAMILY SSF51569 2 287 1.78E-97 T 12-10-2018 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 SMART SM01130 1 289 8.7E-135 T 12-10-2018 IPR002220 DapA-like GO:0016829 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 65.84 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_2358 69c4b568e3210a5b1de0992a45e30d05 291 Gene3D G3DSA:3.20.20.70 1 291 3.3E-106 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_0344 46a19220d6850007cde2bab34a9fa0fa 176 Gene3D G3DSA:3.30.160.20 5 75 2.9E-27 T 12-10-2018 AFE_0344 46a19220d6850007cde2bab34a9fa0fa 176 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 13 167 5.6E-64 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFE_0344 46a19220d6850007cde2bab34a9fa0fa 176 Pfam PF03719 Ribosomal protein S5, C-terminal domain 90 161 1.1E-29 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 AFE_0344 46a19220d6850007cde2bab34a9fa0fa 176 SUPERFAMILY SSF54211 83 163 5.06E-27 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0344 46a19220d6850007cde2bab34a9fa0fa 176 Pfam PF00333 Ribosomal protein S5, N-terminal domain 15 78 1.5E-25 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 AFE_0344 46a19220d6850007cde2bab34a9fa0fa 176 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 167 34.73 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFE_0344 46a19220d6850007cde2bab34a9fa0fa 176 Gene3D G3DSA:3.30.230.10 79 171 1.8E-36 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_0344 46a19220d6850007cde2bab34a9fa0fa 176 SUPERFAMILY SSF54768 12 79 4.08E-20 T 12-10-2018 AFE_2169 daa762e30c12163db5c5a7f91cc791f1 496 SUPERFAMILY SSF56954 25 491 8.11E-76 T 12-10-2018 AFE_2169 daa762e30c12163db5c5a7f91cc791f1 496 Pfam PF02321 Outer membrane efflux protein 103 283 1.7E-26 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_2169 daa762e30c12163db5c5a7f91cc791f1 496 Pfam PF02321 Outer membrane efflux protein 308 489 1.3E-23 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_2169 daa762e30c12163db5c5a7f91cc791f1 496 PIRSF PIRSF001892 40 496 9.4E-79 T 12-10-2018 IPR028351 Cyclolysin transport protein CyaE GO:0005215 AFE_2169 daa762e30c12163db5c5a7f91cc791f1 496 Gene3D G3DSA:1.20.1600.10 95 495 1.0E-76 T 12-10-2018 AFE_2017 39d88523da26acaabd11afe1fcaa5629 244 Pfam PF04012 PspA/IM30 family 2 230 1.8E-26 T 12-10-2018 IPR007157 PspA/IM30 AFE_0324 616472c1749caae5e2093793a756af2e 699 Pfam PF03144 Elongation factor Tu domain 2 330 397 3.0E-15 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFE_0324 616472c1749caae5e2093793a756af2e 699 SUPERFAMILY SSF54980 609 696 6.23E-28 T 12-10-2018 IPR035647 EF-G domain III/V-like AFE_0324 616472c1749caae5e2093793a756af2e 699 PRINTS PR00315 GTP-binding elongation factor signature 58 66 6.4E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0324 616472c1749caae5e2093793a756af2e 699 PRINTS PR00315 GTP-binding elongation factor signature 85 95 6.4E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0324 616472c1749caae5e2093793a756af2e 699 PRINTS PR00315 GTP-binding elongation factor signature 101 112 6.4E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0324 616472c1749caae5e2093793a756af2e 699 PRINTS PR00315 GTP-binding elongation factor signature 137 146 6.4E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0324 616472c1749caae5e2093793a756af2e 699 PRINTS PR00315 GTP-binding elongation factor signature 12 25 6.4E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0324 616472c1749caae5e2093793a756af2e 699 Gene3D G3DSA:2.40.30.10 300 411 1.3E-43 T 12-10-2018 AFE_0324 616472c1749caae5e2093793a756af2e 699 SUPERFAMILY SSF50447 254 408 3.3E-36 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_0324 616472c1749caae5e2093793a756af2e 699 Gene3D G3DSA:3.30.70.870 412 489 8.9E-34 T 12-10-2018 AFE_0324 616472c1749caae5e2093793a756af2e 699 Hamap MF_00054_B Elongation factor G [fusA]. 6 697 111.474 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFE_0324 616472c1749caae5e2093793a756af2e 699 SUPERFAMILY SSF54980 408 486 7.19E-26 T 12-10-2018 IPR035647 EF-G domain III/V-like AFE_0324 616472c1749caae5e2093793a756af2e 699 SMART SM00838 606 693 6.3E-52 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFE_0324 616472c1749caae5e2093793a756af2e 699 SUPERFAMILY SSF52540 6 288 9.44E-105 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0324 616472c1749caae5e2093793a756af2e 699 SMART SM00889 486 604 6.4E-73 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFE_0324 616472c1749caae5e2093793a756af2e 699 Pfam PF00679 Elongation factor G C-terminus 606 692 5.6E-29 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFE_0324 616472c1749caae5e2093793a756af2e 699 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 5.9E-67 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0324 616472c1749caae5e2093793a756af2e 699 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 2.4E-34 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_0324 616472c1749caae5e2093793a756af2e 699 Gene3D G3DSA:3.30.230.10 490 693 1.8E-89 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_0324 616472c1749caae5e2093793a756af2e 699 SUPERFAMILY SSF54211 485 605 6.07E-46 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0324 616472c1749caae5e2093793a756af2e 699 Gene3D G3DSA:3.40.50.300 1 299 1.6E-117 T 12-10-2018 AFE_0324 616472c1749caae5e2093793a756af2e 699 Pfam PF14492 Elongation Factor G, domain II 410 483 7.0E-35 T 12-10-2018 AFE_0324 616472c1749caae5e2093793a756af2e 699 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFE_0324 616472c1749caae5e2093793a756af2e 699 Gene3D G3DSA:3.30.70.240 610 680 1.8E-89 T 12-10-2018 AFE_0324 616472c1749caae5e2093793a756af2e 699 Pfam PF03764 Elongation factor G, domain IV 485 604 3.1E-46 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFE_0324 616472c1749caae5e2093793a756af2e 699 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 698 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFE_1968 923e5b44136538111764f2fb379820a5 661 Pfam PF02080 TrkA-C domain 587 645 6.6E-11 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFE_1968 923e5b44136538111764f2fb379820a5 661 SUPERFAMILY SSF116726 575 645 1.83E-13 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFE_1968 923e5b44136538111764f2fb379820a5 661 Pfam PF00999 Sodium/hydrogen exchanger family 10 373 3.6E-61 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFE_1968 923e5b44136538111764f2fb379820a5 661 SUPERFAMILY SSF51735 404 544 3.39E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1968 923e5b44136538111764f2fb379820a5 661 Gene3D G3DSA:1.20.1530.20 2 384 1.8E-82 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily AFE_1968 923e5b44136538111764f2fb379820a5 661 Gene3D G3DSA:3.40.50.720 404 564 7.2E-39 T 12-10-2018 AFE_1968 923e5b44136538111764f2fb379820a5 661 Pfam PF02254 TrkA-N domain 408 521 3.5E-26 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFE_1968 923e5b44136538111764f2fb379820a5 661 Gene3D G3DSA:3.30.70.1450 577 651 4.8E-12 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFE_2015 da1abcc68e4896bb57556f0ab2c3b5a0 161 Gene3D G3DSA:3.40.630.30 17 155 6.3E-20 T 12-10-2018 AFE_2015 da1abcc68e4896bb57556f0ab2c3b5a0 161 Pfam PF00583 Acetyltransferase (GNAT) family 31 145 1.8E-13 T 12-10-2018 IPR000182 GNAT domain AFE_2015 da1abcc68e4896bb57556f0ab2c3b5a0 161 SUPERFAMILY SSF55729 26 145 2.49E-22 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_0332 187275b96e4a23cae331f19341be4601 111 SUPERFAMILY SSF54843 4 110 5.76E-39 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 AFE_0332 187275b96e4a23cae331f19341be4601 111 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 3.8E-41 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0332 187275b96e4a23cae331f19341be4601 111 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0332 187275b96e4a23cae331f19341be4601 111 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 27.126 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0332 187275b96e4a23cae331f19341be4601 111 Gene3D G3DSA:3.90.470.10 2 111 7.0E-44 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 AFE_0332 187275b96e4a23cae331f19341be4601 111 Pfam PF00237 Ribosomal protein L22p/L17e 6 107 2.5E-33 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 AFE_1975 2ca5597597e68e7e287f5db263a5668a 306 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 90 106 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFE_1975 2ca5597597e68e7e287f5db263a5668a 306 Gene3D G3DSA:1.10.600.10 11 306 1.2E-84 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFE_1975 2ca5597597e68e7e287f5db263a5668a 306 Pfam PF00348 Polyprenyl synthetase 40 282 2.1E-50 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFE_1975 2ca5597597e68e7e287f5db263a5668a 306 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 224 236 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFE_1975 2ca5597597e68e7e287f5db263a5668a 306 SUPERFAMILY SSF48576 12 298 1.6E-77 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFE_3109 21331b083e067f85f545afa35648dea5 206 Gene3D G3DSA:1.20.5.510 7 46 4.0E-7 T 12-10-2018 AFE_3109 21331b083e067f85f545afa35648dea5 206 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 15 193 2.2E-66 T 12-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 AFE_3109 21331b083e067f85f545afa35648dea5 206 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 14 34 3.7E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AFE_3109 21331b083e067f85f545afa35648dea5 206 Pfam PF00355 Rieske [2Fe-2S] domain 115 182 3.7E-9 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFE_3109 21331b083e067f85f545afa35648dea5 206 SUPERFAMILY SSF50022 36 188 6.98E-31 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFE_3109 21331b083e067f85f545afa35648dea5 206 Gene3D G3DSA:2.102.10.10 47 192 1.1E-40 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFE_3109 21331b083e067f85f545afa35648dea5 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 168 180 7.2E-6 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFE_3109 21331b083e067f85f545afa35648dea5 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 155 167 7.2E-6 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFE_3109 21331b083e067f85f545afa35648dea5 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 126 137 7.2E-6 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFE_3109 21331b083e067f85f545afa35648dea5 206 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 7 45 6.1E-16 T 12-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 AFE_1346 5d3e755ee91274cb78de9b0e1009fa0a 343 Pfam PF00535 Glycosyl transferase family 2 32 201 2.4E-21 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFE_1346 5d3e755ee91274cb78de9b0e1009fa0a 343 Gene3D G3DSA:3.90.550.10 2 288 3.5E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_1346 5d3e755ee91274cb78de9b0e1009fa0a 343 SUPERFAMILY SSF53448 30 266 1.61E-40 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 485 83.908 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 SMART SM00116 95 142 9.4E-10 T 12-10-2018 IPR000644 CBS domain AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 SMART SM00116 156 204 1.5E-7 T 12-10-2018 IPR000644 CBS domain AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 SUPERFAMILY SSF51412 4 476 9.16E-123 T 12-10-2018 AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 472 4.6E-161 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 SUPERFAMILY SSF54631 93 202 1.77E-26 T 12-10-2018 AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 SMART SM01240 6 472 0.0 T 12-10-2018 AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 Pfam PF00571 CBS domain 94 138 2.6E-9 T 12-10-2018 IPR000644 CBS domain AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 Pfam PF00571 CBS domain 147 202 6.3E-6 T 12-10-2018 IPR000644 CBS domain AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 Gene3D G3DSA:3.20.20.70 1 485 1.0E-210 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 453 7.1E-191 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 AFE_1777 55c159bcebe5d4a16a435aa6c66ccc6c 486 PIRSF PIRSF000130 1 486 9.6E-201 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 Gene3D G3DSA:3.30.2090.10 176 267 6.3E-250 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 Gene3D G3DSA:1.20.1640.10 13 502 6.3E-250 T 12-10-2018 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 SUPERFAMILY SSF82693 133 320 6.8E-20 T 12-10-2018 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 Gene3D G3DSA:3.30.70.1430 554 653 6.3E-250 T 12-10-2018 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 SUPERFAMILY SSF82866 787 1006 2.22E-33 T 12-10-2018 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 SUPERFAMILY SSF82714 180 261 1.44E-13 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 Gene3D G3DSA:3.30.2090.10 704 792 6.3E-250 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 SUPERFAMILY SSF82693 551 642 2.09E-10 T 12-10-2018 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 Pfam PF00873 AcrB/AcrD/AcrF family 6 1001 2.3E-216 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 Gene3D G3DSA:3.30.70.1440 654 850 6.3E-250 T 12-10-2018 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 PRINTS PR00702 Acriflavin resistance protein family signature 606 620 1.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 PRINTS PR00702 Acriflavin resistance protein family signature 353 374 1.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 PRINTS PR00702 Acriflavin resistance protein family signature 381 405 1.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 PRINTS PR00702 Acriflavin resistance protein family signature 326 349 1.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 PRINTS PR00702 Acriflavin resistance protein family signature 537 554 1.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 1.8E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 Gene3D G3DSA:3.30.70.1320 129 320 6.3E-250 T 12-10-2018 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 Gene3D G3DSA:1.20.1640.10 503 999 6.3E-250 T 12-10-2018 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 SUPERFAMILY SSF82866 286 488 3.4E-35 T 12-10-2018 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 SUPERFAMILY SSF82714 705 788 3.53E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 SUPERFAMILY SSF82693 39 122 4.71E-14 T 12-10-2018 AFE_2035 fb609956b9fe3b474d500132fd389eec 1008 Gene3D G3DSA:3.30.70.1430 38 800 6.3E-250 T 12-10-2018 AFE_1712 c7c19fd4c02d631b7a741fdc41be691e 665 Gene3D G3DSA:3.20.20.450 285 540 8.9E-89 T 12-10-2018 IPR035919 EAL domain superfamily AFE_1712 c7c19fd4c02d631b7a741fdc41be691e 665 SUPERFAMILY SSF141868 288 534 2.35E-80 T 12-10-2018 IPR035919 EAL domain superfamily AFE_1712 c7c19fd4c02d631b7a741fdc41be691e 665 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 107 269 6.6E-40 T 12-10-2018 IPR000160 GGDEF domain AFE_1712 c7c19fd4c02d631b7a741fdc41be691e 665 Pfam PF00990 Diguanylate cyclase, GGDEF domain 112 267 4.4E-45 T 12-10-2018 IPR000160 GGDEF domain AFE_1712 c7c19fd4c02d631b7a741fdc41be691e 665 Gene3D G3DSA:3.30.70.270 112 281 4.4E-52 T 12-10-2018 AFE_1712 c7c19fd4c02d631b7a741fdc41be691e 665 SMART SM00052 281 526 3.0E-97 T 12-10-2018 IPR001633 EAL domain AFE_1712 c7c19fd4c02d631b7a741fdc41be691e 665 SMART SM00267 99 271 3.5E-57 T 12-10-2018 IPR000160 GGDEF domain AFE_1712 c7c19fd4c02d631b7a741fdc41be691e 665 Pfam PF00563 EAL domain 289 521 8.0E-70 T 12-10-2018 IPR001633 EAL domain AFE_1712 c7c19fd4c02d631b7a741fdc41be691e 665 SUPERFAMILY SSF55073 115 270 3.22E-46 T 12-10-2018 IPR029787 Nucleotide cyclase AFE_1825 2534e49152c31f8b42fe99531ecf3e5d 235 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 7 231 36.545 T 12-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 AFE_1825 2534e49152c31f8b42fe99531ecf3e5d 235 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 7 225 1.5E-83 T 12-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 AFE_1825 2534e49152c31f8b42fe99531ecf3e5d 235 Gene3D G3DSA:3.40.50.150 7 231 1.4E-74 T 12-10-2018 AFE_1825 2534e49152c31f8b42fe99531ecf3e5d 235 SUPERFAMILY SSF53335 10 226 5.41E-46 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_1825 2534e49152c31f8b42fe99531ecf3e5d 235 Pfam PF08241 Methyltransferase domain 52 148 1.3E-21 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 224 1.3E-17 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 SUPERFAMILY SSF47789 249 322 2.35E-25 T 12-10-2018 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 Gene3D G3DSA:1.10.150.20 243 325 1.6E-33 T 12-10-2018 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 Gene3D G3DSA:3.30.1360.10 19 224 2.4E-74 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 61 153 4.1E-20 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 249 305 2.6E-23 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 254 324 3.0E-28 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 23 314 7.8E-102 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 SUPERFAMILY SSF56553 52 174 6.28E-36 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 Gene3D G3DSA:2.170.120.12 52 173 2.4E-74 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 SUPERFAMILY SSF55257 12 228 1.96E-23 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 4 315 33.339 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0354 eb3b012f47e74ba2bed7773f2a5589e4 339 SMART SM00662 22 230 3.9E-79 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0548 d946177827db5048102b14846c9e2860 954 Gene3D G3DSA:1.20.120.330 813 951 1.9E-26 T 12-10-2018 AFE_0548 d946177827db5048102b14846c9e2860 954 SUPERFAMILY SSF81301 34 295 4.58E-73 T 12-10-2018 AFE_0548 d946177827db5048102b14846c9e2860 954 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 53 285 1.1E-62 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 AFE_0548 d946177827db5048102b14846c9e2860 954 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 569 805 1.6E-71 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 AFE_0548 d946177827db5048102b14846c9e2860 954 Gene3D G3DSA:3.30.460.100 571 812 7.4E-80 T 12-10-2018 AFE_0548 d946177827db5048102b14846c9e2860 954 Gene3D G3DSA:3.30.460.100 60 289 3.9E-65 T 12-10-2018 AFE_0548 d946177827db5048102b14846c9e2860 954 Gene3D G3DSA:1.20.120.1510 455 570 8.0E-18 T 12-10-2018 AFE_0548 d946177827db5048102b14846c9e2860 954 SUPERFAMILY SSF81301 534 815 4.41E-75 T 12-10-2018 AFE_0548 d946177827db5048102b14846c9e2860 954 Pfam PF08335 GlnD PII-uridylyltransferase 318 441 1.7E-37 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AFE_0548 d946177827db5048102b14846c9e2860 954 Pfam PF08335 GlnD PII-uridylyltransferase 827 913 5.7E-8 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AFE_0548 d946177827db5048102b14846c9e2860 954 Gene3D G3DSA:1.20.120.330 294 446 1.2E-48 T 12-10-2018 AFE_0548 d946177827db5048102b14846c9e2860 954 SUPERFAMILY SSF81593 296 443 5.34E-37 T 12-10-2018 AFE_0548 d946177827db5048102b14846c9e2860 954 SUPERFAMILY SSF81593 816 949 9.42E-24 T 12-10-2018 AFE_0548 d946177827db5048102b14846c9e2860 954 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 49 951 17.065 T 12-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 AFE_0683 f1bea1dacd9ff28f597b95d1395aba2e 784 SMART SM00487 168 363 1.6E-20 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_0683 f1bea1dacd9ff28f597b95d1395aba2e 784 Pfam PF08463 EcoEI R protein C-terminal 623 777 5.1E-31 T 12-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 AFE_0683 f1bea1dacd9ff28f597b95d1395aba2e 784 Pfam PF04851 Type III restriction enzyme, res subunit 170 328 6.5E-41 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFE_0683 f1bea1dacd9ff28f597b95d1395aba2e 784 Gene3D G3DSA:3.40.50.300 150 345 2.9E-70 T 12-10-2018 AFE_0683 f1bea1dacd9ff28f597b95d1395aba2e 784 SUPERFAMILY SSF52540 159 365 3.43E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0683 f1bea1dacd9ff28f597b95d1395aba2e 784 Gene3D G3DSA:3.90.1570.30 1 148 7.8E-46 T 12-10-2018 AFE_0683 f1bea1dacd9ff28f597b95d1395aba2e 784 Gene3D G3DSA:3.40.50.300 346 570 5.2E-51 T 12-10-2018 AFE_0683 f1bea1dacd9ff28f597b95d1395aba2e 784 Pfam PF00271 Helicase conserved C-terminal domain 415 528 1.9E-4 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0683 f1bea1dacd9ff28f597b95d1395aba2e 784 SUPERFAMILY SSF52540 274 533 2.03E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1910 34fca342c79fb5f846f3bdd670c21a7c 413 SUPERFAMILY SSF53901 2 251 2.22E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_1910 34fca342c79fb5f846f3bdd670c21a7c 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 9.1E-60 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal AFE_1910 34fca342c79fb5f846f3bdd670c21a7c 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 409 7.4E-201 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 AFE_1910 34fca342c79fb5f846f3bdd670c21a7c 413 Gene3D G3DSA:3.40.47.10 1 254 4.8E-93 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_1910 34fca342c79fb5f846f3bdd670c21a7c 413 SMART SM00825 Beta-ketoacyl synthase 5 413 3.5E-18 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AFE_1910 34fca342c79fb5f846f3bdd670c21a7c 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 1.0E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal AFE_1910 34fca342c79fb5f846f3bdd670c21a7c 413 PIRSF PIRSF000447 1 413 6.6E-190 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 AFE_1910 34fca342c79fb5f846f3bdd670c21a7c 413 Gene3D G3DSA:3.40.47.10 256 400 1.5E-58 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_1910 34fca342c79fb5f846f3bdd670c21a7c 413 SUPERFAMILY SSF53901 214 411 1.66E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_1910 34fca342c79fb5f846f3bdd670c21a7c 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site AFE_3028 c2bcb1b42f63ce7f833ebb2150e1969f 189 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 18 187 1.9E-27 T 12-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related AFE_3028 c2bcb1b42f63ce7f833ebb2150e1969f 189 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 16 187 7.8E-40 T 12-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 SUPERFAMILY SSF52540 12 347 1.3E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 11 597 2.1E-241 T 12-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 Pfam PF00271 Helicase conserved C-terminal domain 222 328 9.2E-16 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 Gene3D G3DSA:3.40.50.300 205 338 8.4E-39 T 12-10-2018 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 Pfam PF00570 HRDC domain 531 597 2.0E-21 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 SMART SM00341 527 602 5.0E-13 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 Pfam PF09382 RQC domain 405 514 1.2E-36 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 Pfam PF00270 DEAD/DEAH box helicase 26 183 1.6E-19 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 Gene3D G3DSA:3.40.50.300 4 204 8.9E-78 T 12-10-2018 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 SUPERFAMILY SSF52540 204 456 2.36E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 SMART SM00490 248 329 2.4E-26 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 SMART SM00487 18 214 4.3E-30 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 11 462 1.1E-158 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 SUPERFAMILY SSF47819 525 599 7.2E-22 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 Pfam PF16124 RecQ zinc-binding 341 403 2.5E-20 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 SMART SM00956 410 513 1.9E-47 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 Gene3D G3DSA:1.10.10.10 339 523 1.6E-52 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2194 be04b5f868f0404cf87aa5133279e1e2 603 Gene3D G3DSA:1.10.150.80 529 599 1.9E-22 T 12-10-2018 AFE_0046 5900832ff722c89202c261cd1ca1f1b1 133 SMART SM00450 8 125 5.8E-8 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_0046 5900832ff722c89202c261cd1ca1f1b1 133 Pfam PF00581 Rhodanese-like domain 12 119 1.2E-9 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_0046 5900832ff722c89202c261cd1ca1f1b1 133 SUPERFAMILY SSF52821 6 126 2.62E-19 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_0046 5900832ff722c89202c261cd1ca1f1b1 133 Gene3D G3DSA:3.40.250.10 2 127 7.3E-20 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Gene3D G3DSA:3.30.559.10 280 501 4.8E-56 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Pfam PF00364 Biotin-requiring enzyme 7 77 1.5E-11 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Pfam PF00364 Biotin-requiring enzyme 114 183 7.9E-14 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 SUPERFAMILY SSF51230 112 201 7.59E-22 T 12-10-2018 IPR011053 Single hybrid motif AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 299 500 3.3E-50 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Gene3D G3DSA:4.10.320.10 236 277 2.2E-10 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 942 962 2.4E-48 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 515 537 2.4E-48 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 548 563 2.4E-48 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 777 791 2.4E-48 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 855 876 2.4E-48 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 820 827 2.4E-48 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 687 712 2.4E-48 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 920 935 2.4E-48 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 647 656 2.4E-48 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 SUPERFAMILY SSF51905 510 849 3.2E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 SUPERFAMILY SSF52777 289 500 2.71E-53 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 SUPERFAMILY SSF47005 235 276 6.02E-8 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 136 165 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 549 559 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Gene3D G3DSA:3.30.390.30 860 975 6.8E-32 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Gene3D G3DSA:2.40.50.100 108 203 6.1E-25 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Gene3D G3DSA:2.40.50.100 2 99 1.1E-21 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 862 967 1.1E-25 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Gene3D G3DSA:3.50.50.60 661 786 5.9E-97 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 29 58 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Pfam PF02817 e3 binding domain 240 273 1.8E-9 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 SUPERFAMILY SSF55424 862 975 4.3E-30 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 776 792 6.8E-28 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 687 705 6.8E-28 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 516 535 6.8E-28 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 805 827 6.8E-28 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 644 662 6.8E-28 T 12-10-2018 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Gene3D G3DSA:3.50.50.60 516 845 5.9E-97 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 515 840 2.3E-67 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_3068 00aa8969b8ad2de48a1e278d5d68b88a 983 SUPERFAMILY SSF51230 4 92 9.82E-20 T 12-10-2018 IPR011053 Single hybrid motif AFE_2161 3ee5f2143e98307b5f7e1b6f8afd471e 621 Gene3D G3DSA:3.10.620.30 246 381 5.4E-33 T 12-10-2018 AFE_2161 3ee5f2143e98307b5f7e1b6f8afd471e 621 Pfam PF01841 Transglutaminase-like superfamily 257 338 1.4E-6 T 12-10-2018 IPR002931 Transglutaminase-like AFE_2161 3ee5f2143e98307b5f7e1b6f8afd471e 621 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 45 207 1.4E-26 T 12-10-2018 IPR024618 Domain of unknown function DUF3857 AFE_2161 3ee5f2143e98307b5f7e1b6f8afd471e 621 SUPERFAMILY SSF54001 204 376 1.18E-7 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFE_2161 3ee5f2143e98307b5f7e1b6f8afd471e 621 Gene3D G3DSA:2.60.40.3140 34 233 7.1E-26 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 Pfam PF00689 Cation transporting ATPase, C-terminus 659 819 1.3E-27 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 Pfam PF00702 haloacid dehalogenase-like hydrolase 303 587 3.2E-24 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 SUPERFAMILY SSF81653 104 206 2.09E-25 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 Pfam PF00690 Cation transporter/ATPase, N-terminus 11 61 4.4E-14 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 Gene3D G3DSA:3.40.1110.10 316 478 2.7E-169 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 308 314 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 SUPERFAMILY SSF81665 10 817 6.93E-96 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 606 631 8.9E-15 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 546 562 8.9E-15 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 434 452 8.9E-15 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 574 590 8.9E-15 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 Gene3D G3DSA:2.70.150.10 10 208 2.7E-169 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 Gene3D G3DSA:1.20.1110.10 28 726 2.7E-169 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 Gene3D G3DSA:3.40.50.1000 303 614 2.7E-169 T 12-10-2018 IPR023214 HAD superfamily AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 Pfam PF00122 E1-E2 ATPase 102 286 3.8E-49 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 540 663 1.2E-30 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 73 328 6.3E-45 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 SUPERFAMILY SSF56784 304 677 6.07E-55 T 12-10-2018 IPR036412 HAD-like superfamily AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 574 593 3.0E-40 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 151 165 3.0E-40 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 493 503 3.0E-40 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 598 610 3.0E-40 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 471 482 3.0E-40 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 306 320 3.0E-40 T 12-10-2018 AFE_1988 53625e5af0c484b0f3399a425f5a185e 827 SMART SM00831 2 66 6.6E-12 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFE_1037 dbfbc0deff2bfedfbedc4bfdedd378eb 769 Gene3D G3DSA:3.40.50.300 139 405 8.5E-13 T 12-10-2018 AFE_1037 dbfbc0deff2bfedfbedc4bfdedd378eb 769 SUPERFAMILY SSF52540 153 670 1.33E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1037 dbfbc0deff2bfedfbedc4bfdedd378eb 769 TIGRFAM TIGR03117 cas_csf4: CRISPR type AFERR-associated DEAD/DEAH-box helicase Csf4 335 758 3.5E-193 T 12-10-2018 IPR017548 CRISPR-associated DEAD/DEAH-box helicase Csf4 AFE_2565 9ac6b6ca81a429e36c1c65604b967040 602 Gene3D G3DSA:3.40.710.10 245 597 3.8E-96 T 12-10-2018 AFE_2565 9ac6b6ca81a429e36c1c65604b967040 602 SUPERFAMILY SSF56601 246 595 3.64E-92 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_2565 9ac6b6ca81a429e36c1c65604b967040 602 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 229 2.5E-42 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFE_2565 9ac6b6ca81a429e36c1c65604b967040 602 Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. 2 596 46.154 T 12-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_2565 9ac6b6ca81a429e36c1c65604b967040 602 Gene3D G3DSA:3.90.1310.10 60 239 4.6E-42 T 12-10-2018 AFE_2565 9ac6b6ca81a429e36c1c65604b967040 602 Pfam PF00905 Penicillin binding protein transpeptidase domain 263 589 1.2E-67 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFE_2565 9ac6b6ca81a429e36c1c65604b967040 602 Gene3D G3DSA:3.30.1390.30 81 156 4.6E-42 T 12-10-2018 AFE_2565 9ac6b6ca81a429e36c1c65604b967040 602 SUPERFAMILY SSF56519 53 245 1.22E-44 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 AFE_2565 9ac6b6ca81a429e36c1c65604b967040 602 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 15 593 3.9E-205 T 12-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 362 429 7.9E-32 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 Gene3D G3DSA:1.10.1750.10 359 452 2.9E-35 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 14 451 32.405 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 Pfam PF00308 Bacterial dnaA protein 117 333 5.7E-93 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 Gene3D G3DSA:3.40.50.300 113 281 3.1E-51 T 12-10-2018 AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 Gene3D G3DSA:1.10.8.60 283 353 3.3E-23 T 12-10-2018 AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 SMART SM00382 149 362 1.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 SUPERFAMILY SSF52540 116 329 3.28E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 SMART SM00760 360 429 1.2E-41 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 Gene3D G3DSA:3.30.300.180 14 112 1.3E-19 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 17 449 1.1E-173 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 SUPERFAMILY SSF48295 348 450 6.8E-36 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 Pfam PF11638 DnaA N-terminal domain 15 75 5.8E-15 T 12-10-2018 IPR024633 DnaA N-terminal domain AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 ProSitePatterns PS01008 DnaA protein signature. 410 429 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 182 196 1.7E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 214 228 1.7E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 150 170 1.7E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 248 275 1.7E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFE_3309 0a8e69cf5b38b9211924a4d55e96fd37 452 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 410 429 1.7E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFE_3219 504a17458927dbddc5714259325cb2cd 313 Gene3D G3DSA:1.20.58.340 257 313 6.4E-11 T 12-10-2018 AFE_3219 504a17458927dbddc5714259325cb2cd 313 Gene3D G3DSA:3.30.460.20 11 130 2.4E-12 T 12-10-2018 AFE_3219 504a17458927dbddc5714259325cb2cd 313 SUPERFAMILY SSF143865 18 245 6.54E-35 T 12-10-2018 AFE_3219 504a17458927dbddc5714259325cb2cd 313 Gene3D G3DSA:1.20.58.340 131 255 5.0E-15 T 12-10-2018 AFE_3219 504a17458927dbddc5714259325cb2cd 313 Pfam PF01544 CorA-like Mg2+ transporter protein 24 309 1.6E-54 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFE_3219 504a17458927dbddc5714259325cb2cd 313 SUPERFAMILY SSF144083 250 310 1.07E-12 T 12-10-2018 AFE_3039 553a73a23aadbd898f0c2e9ada0bf5fa 423 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 7.4E-178 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_3039 553a73a23aadbd898f0c2e9ada0bf5fa 423 Gene3D G3DSA:3.65.10.10 7 413 3.7E-166 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFE_3039 553a73a23aadbd898f0c2e9ada0bf5fa 423 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 44.784 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_3039 553a73a23aadbd898f0c2e9ada0bf5fa 423 SUPERFAMILY SSF55205 1 417 6.7E-140 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFE_3039 553a73a23aadbd898f0c2e9ada0bf5fa 423 Gene3D G3DSA:3.65.10.10 21 229 3.7E-166 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFE_3039 553a73a23aadbd898f0c2e9ada0bf5fa 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 406 7.1E-108 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFE_2766 34612adddb97b5ccab9fa070bb547123 315 SMART SM01400 6 122 1.8E-76 T 12-10-2018 AFE_2766 34612adddb97b5ccab9fa070bb547123 315 Gene3D G3DSA:3.40.50.2020 149 290 1.1E-126 T 12-10-2018 AFE_2766 34612adddb97b5ccab9fa070bb547123 315 SUPERFAMILY SSF53271 71 304 3.95E-64 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFE_2766 34612adddb97b5ccab9fa070bb547123 315 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 130 145 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 AFE_2766 34612adddb97b5ccab9fa070bb547123 315 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 6 314 49.319 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 AFE_2766 34612adddb97b5ccab9fa070bb547123 315 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 313 2.7E-122 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFE_2766 34612adddb97b5ccab9fa070bb547123 315 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 122 2.9E-47 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFE_2766 34612adddb97b5ccab9fa070bb547123 315 Pfam PF14572 Phosphoribosyl synthetase-associated domain 201 313 2.3E-31 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFE_2766 34612adddb97b5ccab9fa070bb547123 315 Gene3D G3DSA:3.40.50.2020 9 302 1.1E-126 T 12-10-2018 AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 2.9E-211 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 SMART SM00382 170 356 2.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 SUPERFAMILY SSF68912 1 46 2.39E-10 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 SUPERFAMILY SSF52540 90 371 5.69E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 Pfam PF07498 Rho termination factor, N-terminal domain 5 46 4.3E-14 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 2.0E-23 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 SMART SM00959 5 47 1.6E-13 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 245.766 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 SMART SM00357 52 118 9.2E-20 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 Gene3D G3DSA:3.40.50.300 130 417 3.8E-129 T 12-10-2018 AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 Gene3D G3DSA:1.10.720.10 1 46 2.0E-17 T 12-10-2018 AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 SUPERFAMILY SSF50249 49 125 2.78E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 Gene3D G3DSA:2.40.50.140 47 123 1.3E-33 T 12-10-2018 AFE_0658 86f6c9eb2e54fa806d58ea99905dc5e5 418 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 2.9E-31 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 Pfam PF02421 Ferrous iron transport protein B 4 155 1.9E-58 T 12-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 SUPERFAMILY SSF52540 3 162 8.36E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 Gene3D G3DSA:3.40.50.300 2 170 1.2E-41 T 12-10-2018 AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 156 3.7E-12 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 6.6E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 52 67 6.6E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 6.6E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 690 3.4E-172 T 12-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 Pfam PF07670 Nucleoside recognition 509 693 1.4E-27 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 Pfam PF07670 Nucleoside recognition 347 438 4.6E-11 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFE_2524 b055b30f8731d6606ecb70f1ea3a5e9d 766 Pfam PF07664 Ferrous iron transport protein B C terminus 451 503 1.3E-22 T 12-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 AFE_0773 f5300e4bf03073c8903e1f5d5612b10f 347 SUPERFAMILY SSF51556 13 334 3.85E-78 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFE_0773 f5300e4bf03073c8903e1f5d5612b10f 347 Hamap MF_01962 Adenine deaminase. 14 325 75.31 T 12-10-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 AFE_0773 f5300e4bf03073c8903e1f5d5612b10f 347 Gene3D G3DSA:3.20.20.140 9 343 2.5E-97 T 12-10-2018 AFE_0773 f5300e4bf03073c8903e1f5d5612b10f 347 Pfam PF00962 Adenosine/AMP deaminase 18 333 3.1E-66 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 AFE_0773 f5300e4bf03073c8903e1f5d5612b10f 347 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 18 334 2.0E-103 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 AFE_0739 96b640e7095c7d90e56623205241ad45 354 Pfam PF11104 Type IV pilus assembly protein PilM; 11 351 2.4E-93 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM AFE_0739 96b640e7095c7d90e56623205241ad45 354 SUPERFAMILY SSF53067 50 172 2.33E-11 T 12-10-2018 AFE_0739 96b640e7095c7d90e56623205241ad45 354 Gene3D G3DSA:3.30.1490.300 85 144 6.2E-79 T 12-10-2018 AFE_0739 96b640e7095c7d90e56623205241ad45 354 Gene3D G3DSA:3.30.420.40 189 316 6.2E-79 T 12-10-2018 AFE_0739 96b640e7095c7d90e56623205241ad45 354 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 9 351 2.1E-81 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM AFE_0739 96b640e7095c7d90e56623205241ad45 354 SUPERFAMILY SSF53067 194 350 3.33E-9 T 12-10-2018 AFE_0739 96b640e7095c7d90e56623205241ad45 354 PIRSF PIRSF019169 2 353 2.6E-100 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM AFE_0739 96b640e7095c7d90e56623205241ad45 354 Gene3D G3DSA:3.30.420.40 10 350 6.2E-79 T 12-10-2018 AFE_0352 ea2945860f28f284538a96175425a351 131 Pfam PF00411 Ribosomal protein S11 21 130 4.2E-50 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFE_0352 ea2945860f28f284538a96175425a351 131 Gene3D G3DSA:3.30.420.80 3 131 2.2E-54 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 AFE_0352 ea2945860f28f284538a96175425a351 131 PIRSF PIRSF002131 1 131 1.3E-53 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFE_0352 ea2945860f28f284538a96175425a351 131 ProSitePatterns PS00054 Ribosomal protein S11 signature. 99 121 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site AFE_0352 ea2945860f28f284538a96175425a351 131 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 131 33.0 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFE_0352 ea2945860f28f284538a96175425a351 131 SUPERFAMILY SSF53137 15 131 4.8E-48 T 12-10-2018 AFE_0352 ea2945860f28f284538a96175425a351 131 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 12 128 2.6E-56 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_3131 7d3c16782edf5f046edcfe198a64bcf0 82 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 48 1.6E-19 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFE_3131 7d3c16782edf5f046edcfe198a64bcf0 82 Pfam PF02416 mttA/Hcf106 family 5 50 9.0E-12 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AFE_3131 7d3c16782edf5f046edcfe198a64bcf0 82 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 77 19.699 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFE_1676 fa02055b7ad2157d7cd563ddfbbd3207 393 Gene3D G3DSA:3.30.70.100 296 393 3.2E-9 T 12-10-2018 AFE_1676 fa02055b7ad2157d7cd563ddfbbd3207 393 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 283 1.2E-62 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFE_1676 fa02055b7ad2157d7cd563ddfbbd3207 393 SUPERFAMILY SSF51569 2 282 1.3E-56 T 12-10-2018 AFE_1676 fa02055b7ad2157d7cd563ddfbbd3207 393 Gene3D G3DSA:3.20.20.70 1 288 5.2E-67 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1676 fa02055b7ad2157d7cd563ddfbbd3207 393 SUPERFAMILY SSF54909 307 389 6.79E-8 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFE_1676 fa02055b7ad2157d7cd563ddfbbd3207 393 Pfam PF07876 Stress responsive A/B Barrel Domain 309 388 6.2E-7 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel AFE_0565 134d519e21802272185ea1dd339119ce 734 SUPERFAMILY SSF109604 17 201 2.98E-72 T 12-10-2018 AFE_0565 134d519e21802272185ea1dd339119ce 734 Gene3D G3DSA:3.30.70.260 655 734 1.4E-16 T 12-10-2018 AFE_0565 134d519e21802272185ea1dd339119ce 734 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 36 730 1.9E-241 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 AFE_0565 134d519e21802272185ea1dd339119ce 734 SUPERFAMILY SSF81301 190 401 5.89E-64 T 12-10-2018 AFE_0565 134d519e21802272185ea1dd339119ce 734 SMART SM00471 51 163 2.6E-9 T 12-10-2018 IPR003607 HD/PDEase domain AFE_0565 134d519e21802272185ea1dd339119ce 734 Pfam PF02824 TGS domain 397 456 2.1E-22 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFE_0565 134d519e21802272185ea1dd339119ce 734 SMART SM00954 245 355 1.1E-66 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 AFE_0565 134d519e21802272185ea1dd339119ce 734 Pfam PF13328 HD domain 36 185 1.7E-54 T 12-10-2018 IPR003607 HD/PDEase domain AFE_0565 134d519e21802272185ea1dd339119ce 734 Gene3D G3DSA:3.30.460.10 203 335 3.7E-49 T 12-10-2018 AFE_0565 134d519e21802272185ea1dd339119ce 734 SUPERFAMILY SSF55021 659 732 6.11E-8 T 12-10-2018 AFE_0565 134d519e21802272185ea1dd339119ce 734 Pfam PF13291 ACT domain 654 731 5.8E-18 T 12-10-2018 IPR002912 ACT domain AFE_0565 134d519e21802272185ea1dd339119ce 734 Pfam PF04607 Region found in RelA / SpoT proteins 245 354 6.6E-37 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 AFE_0565 134d519e21802272185ea1dd339119ce 734 Gene3D G3DSA:1.10.3210.10 14 200 1.5E-79 T 12-10-2018 AFE_0565 134d519e21802272185ea1dd339119ce 734 SUPERFAMILY SSF81271 384 456 7.19E-22 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFE_0565 134d519e21802272185ea1dd339119ce 734 Gene3D G3DSA:3.10.20.30 390 463 6.1E-31 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_3286 b36d2124bbc2714808ecd4b7a20b1b8d 585 Pfam PF00374 Nickel-dependent hydrogenase 40 570 2.4E-231 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AFE_3286 b36d2124bbc2714808ecd4b7a20b1b8d 585 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 561 570 - T 12-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AFE_3286 b36d2124bbc2714808ecd4b7a20b1b8d 585 Gene3D G3DSA:1.10.645.10 1 570 2.6E-254 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_3286 b36d2124bbc2714808ecd4b7a20b1b8d 585 SUPERFAMILY SSF56762 4 570 1.2E-173 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_3286 b36d2124bbc2714808ecd4b7a20b1b8d 585 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 40 65 - T 12-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 Gene3D G3DSA:3.40.50.1440 4 220 9.1E-81 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 SUPERFAMILY SSF52490 13 208 1.7E-67 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 359 37.452 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 Gene3D G3DSA:3.30.1330.20 221 330 1.7E-33 T 12-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.4E-49 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.4E-49 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.4E-49 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.4E-49 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 SMART SM00864 13 205 6.2E-110 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 Pfam PF12327 FtsZ family, C-terminal domain 222 317 6.4E-34 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 SUPERFAMILY SSF55307 204 319 1.1E-40 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 172 9.4E-42 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 320 6.3E-131 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFE_0200 717725e226f3f7eda71cd5c57d3853c9 387 SMART SM00865 207 325 1.3E-54 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 SUPERFAMILY SSF48557 3 429 8.33E-131 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 428 2.1E-27 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 Gene3D G3DSA:1.10.275.10 1 92 4.4E-34 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 Gene3D G3DSA:1.20.200.10 93 347 2.4E-92 T 12-10-2018 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 429 9.8E-158 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 SMART SM00998 349 429 1.3E-39 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 1.2E-28 T 12-10-2018 IPR000362 Fumarate lyase family AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 1.2E-28 T 12-10-2018 IPR000362 Fumarate lyase family AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 1.2E-28 T 12-10-2018 IPR000362 Fumarate lyase family AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 1.2E-28 T 12-10-2018 IPR000362 Fumarate lyase family AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 Pfam PF00206 Lyase 6 282 3.4E-54 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 1.4E-10 T 12-10-2018 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 1.4E-10 T 12-10-2018 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 1.4E-10 T 12-10-2018 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 1.4E-10 T 12-10-2018 AFE_2356 100ecea59baa656e284bfedb1d0b918c 435 Gene3D G3DSA:1.10.40.30 349 430 3.1E-30 T 12-10-2018 AFE_2131 88673264cc8c255c317eb8b8c4ba04a5 506 Gene3D G3DSA:3.40.309.10 266 464 3.2E-162 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFE_2131 88673264cc8c255c317eb8b8c4ba04a5 506 Pfam PF00171 Aldehyde dehydrogenase family 27 493 1.5E-163 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFE_2131 88673264cc8c255c317eb8b8c4ba04a5 506 Gene3D G3DSA:3.40.605.10 23 492 3.2E-162 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFE_2131 88673264cc8c255c317eb8b8c4ba04a5 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFE_2131 88673264cc8c255c317eb8b8c4ba04a5 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFE_2131 88673264cc8c255c317eb8b8c4ba04a5 506 SUPERFAMILY SSF53720 13 497 7.2E-163 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFE_2027 aa8932b3193a314662502ad7ca922ed1 330 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 13 330 41.363 T 12-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 AFE_2027 aa8932b3193a314662502ad7ca922ed1 330 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 101 119 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFE_2027 aa8932b3193a314662502ad7ca922ed1 330 Gene3D G3DSA:3.20.20.70 15 256 2.5E-65 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2027 aa8932b3193a314662502ad7ca922ed1 330 Pfam PF01207 Dihydrouridine synthase (Dus) 21 271 3.5E-62 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFE_2027 aa8932b3193a314662502ad7ca922ed1 330 SUPERFAMILY SSF51395 19 321 4.48E-60 T 12-10-2018 AFE_1999 3108077a7ea25c5a05d2175081317321 183 Pfam PF00765 Autoinducer synthase 18 182 2.4E-23 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 AFE_1999 3108077a7ea25c5a05d2175081317321 183 SUPERFAMILY SSF55729 10 183 1.57E-35 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_1999 3108077a7ea25c5a05d2175081317321 183 Gene3D G3DSA:3.40.630.30 1 183 4.4E-54 T 12-10-2018 AFE_1999 3108077a7ea25c5a05d2175081317321 183 ProSitePatterns PS00949 Autoinducer synthase family signature. 22 47 - T 12-10-2018 IPR018311 Autoinducer synthesis, conserved site KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 AFE_1999 3108077a7ea25c5a05d2175081317321 183 PRINTS PR01549 Autoinducer synthesis protein signature 62 80 7.6E-17 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 AFE_1999 3108077a7ea25c5a05d2175081317321 183 PRINTS PR01549 Autoinducer synthesis protein signature 95 107 7.6E-17 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 AFE_1999 3108077a7ea25c5a05d2175081317321 183 PRINTS PR01549 Autoinducer synthesis protein signature 144 165 7.6E-17 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 AFE_1999 3108077a7ea25c5a05d2175081317321 183 PRINTS PR01549 Autoinducer synthesis protein signature 18 37 7.6E-17 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 AFE_1999 3108077a7ea25c5a05d2175081317321 183 PRINTS PR01549 Autoinducer synthesis protein signature 38 60 7.6E-17 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 AFE_1648 356bd7b8f10ffa52ff611f49028efb26 148 Pfam PF00011 Hsp20/alpha crystallin family 48 147 6.5E-24 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain AFE_1648 356bd7b8f10ffa52ff611f49028efb26 148 SUPERFAMILY SSF49764 29 147 1.66E-35 T 12-10-2018 IPR008978 HSP20-like chaperone AFE_1648 356bd7b8f10ffa52ff611f49028efb26 148 Gene3D G3DSA:2.60.40.790 8 148 1.7E-34 T 12-10-2018 IPR008978 HSP20-like chaperone AFE_0639 19081226721049cca6cf13a095c80c79 1079 SUPERFAMILY SSF52335 935 1070 8.24E-40 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFE_0639 19081226721049cca6cf13a095c80c79 1079 SMART SM00851 955 1041 2.1E-34 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain AFE_0639 19081226721049cca6cf13a095c80c79 1079 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1069 13.456 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Pfam PF02142 MGS-like domain 956 1041 1.0E-20 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain AFE_0639 19081226721049cca6cf13a095c80c79 1079 SUPERFAMILY SSF48108 395 552 3.4E-50 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 SUPERFAMILY SSF52440 1 127 5.47E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFE_0639 19081226721049cca6cf13a095c80c79 1079 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 708 722 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFE_0639 19081226721049cca6cf13a095c80c79 1079 SUPERFAMILY SSF56059 672 933 3.01E-103 T 12-10-2018 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Gene3D G3DSA:3.40.50.20 1 116 1.5E-48 T 12-10-2018 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.1E-75 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 672 874 1.5E-37 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFE_0639 19081226721049cca6cf13a095c80c79 1079 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1050 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Gene3D G3DSA:3.40.50.1380 937 1073 3.5E-39 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFE_0639 19081226721049cca6cf13a095c80c79 1079 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Gene3D G3DSA:1.10.1030.10 403 552 7.5E-49 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Gene3D G3DSA:3.30.470.20 664 935 1.0E-114 T 12-10-2018 AFE_0639 19081226721049cca6cf13a095c80c79 1079 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Gene3D G3DSA:3.40.50.20 555 661 4.9E-49 T 12-10-2018 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1062 13.13 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 SUPERFAMILY SSF52440 558 674 1.19E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFE_0639 19081226721049cca6cf13a095c80c79 1079 SUPERFAMILY SSF56059 128 400 2.12E-109 T 12-10-2018 AFE_0639 19081226721049cca6cf13a095c80c79 1079 SMART SM01096 423 546 6.7E-66 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 426 546 3.1E-38 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0639 19081226721049cca6cf13a095c80c79 1079 Gene3D G3DSA:3.30.470.20 119 402 6.7E-131 T 12-10-2018 AFE_2067 188c165eb6e5020ee84bbebdedb40d1f 294 SUPERFAMILY SSF52096 33 290 4.97E-89 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFE_2067 188c165eb6e5020ee84bbebdedb40d1f 294 Pfam PF01039 Carboxyl transferase domain 105 248 3.2E-17 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AFE_2067 188c165eb6e5020ee84bbebdedb40d1f 294 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 292 2.3E-127 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_2067 188c165eb6e5020ee84bbebdedb40d1f 294 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 289 39.167 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_2067 188c165eb6e5020ee84bbebdedb40d1f 294 Gene3D G3DSA:3.90.226.10 33 293 2.8E-88 T 12-10-2018 AFE_2067 188c165eb6e5020ee84bbebdedb40d1f 294 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 171 189 4.6E-39 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_2067 188c165eb6e5020ee84bbebdedb40d1f 294 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 259 268 4.6E-39 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_2067 188c165eb6e5020ee84bbebdedb40d1f 294 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 208 225 4.6E-39 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_2067 188c165eb6e5020ee84bbebdedb40d1f 294 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 137 151 4.6E-39 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_2067 188c165eb6e5020ee84bbebdedb40d1f 294 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 237 248 4.6E-39 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_2262 fc8dbb169b06dfa546c1fbf3a28a5468 186 Gene3D G3DSA:3.90.870.10 4 185 9.1E-48 T 12-10-2018 AFE_2262 fc8dbb169b06dfa546c1fbf3a28a5468 186 SUPERFAMILY SSF55821 4 185 4.27E-42 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFE_2262 fc8dbb169b06dfa546c1fbf3a28a5468 186 Pfam PF01300 Telomere recombination 18 185 6.8E-31 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFE_2262 fc8dbb169b06dfa546c1fbf3a28a5468 186 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 8 185 31.365 T 12-10-2018 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 AFE_0791 51131474d825c26c65d405ced1e156ed 448 Gene3D G3DSA:1.20.1530.20 21 423 2.6E-91 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily AFE_0791 51131474d825c26c65d405ced1e156ed 448 Pfam PF00999 Sodium/hydrogen exchanger family 28 415 1.1E-52 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFE_1465 de664243f4bb35c150ddae75fdf9b787 154 Gene3D G3DSA:1.20.120.910 24 154 7.3E-40 T 12-10-2018 AFE_1465 de664243f4bb35c150ddae75fdf9b787 154 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 111 146 6.5E-12 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 AFE_1465 de664243f4bb35c150ddae75fdf9b787 154 SUPERFAMILY SSF109635 19 112 9.42E-34 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily AFE_1465 de664243f4bb35c150ddae75fdf9b787 154 PRINTS PR00618 DksA/TraR zinc finger signature 116 127 4.0E-5 T 12-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria AFE_1465 de664243f4bb35c150ddae75fdf9b787 154 PRINTS PR00618 DksA/TraR zinc finger signature 128 140 4.0E-5 T 12-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria AFE_1465 de664243f4bb35c150ddae75fdf9b787 154 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 30 152 29.034 T 12-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 AFE_1465 de664243f4bb35c150ddae75fdf9b787 154 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 116 140 - T 12-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site AFE_1465 de664243f4bb35c150ddae75fdf9b787 154 SUPERFAMILY SSF57716 113 151 1.43E-10 T 12-10-2018 AFE_1465 de664243f4bb35c150ddae75fdf9b787 154 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 34 142 1.9E-49 T 12-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 AFE_2355 00863ccff63bd179ba42ef00f24a5448 240 Gene3D G3DSA:3.30.200.20 7 231 8.5E-93 T 12-10-2018 AFE_2355 00863ccff63bd179ba42ef00f24a5448 240 SUPERFAMILY SSF56104 7 232 2.06E-79 T 12-10-2018 AFE_2355 00863ccff63bd179ba42ef00f24a5448 240 Pfam PF01259 SAICAR synthetase 7 231 2.7E-64 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2355 00863ccff63bd179ba42ef00f24a5448 240 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 234 31.138 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2355 00863ccff63bd179ba42ef00f24a5448 240 Gene3D G3DSA:3.30.470.20 85 220 8.5E-93 T 12-10-2018 AFE_2355 00863ccff63bd179ba42ef00f24a5448 240 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2355 00863ccff63bd179ba42ef00f24a5448 240 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2355 00863ccff63bd179ba42ef00f24a5448 240 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 7 233 3.1E-70 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 AFE_1766 416c6a1cdc37af321f84cad62f1dfefb 208 SUPERFAMILY SSF53639 50 195 1.77E-15 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFE_1766 416c6a1cdc37af321f84cad62f1dfefb 208 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 52 130 1.1E-9 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFE_1766 416c6a1cdc37af321f84cad62f1dfefb 208 Gene3D G3DSA:3.40.225.10 31 208 3.4E-17 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 ProSitePatterns PS00211 ABC transporters family signature. 621 635 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 SUPERFAMILY SSF52540 478 715 9.3E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 SUPERFAMILY SSF90123 155 467 1.96E-68 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 Gene3D G3DSA:1.20.1560.10 153 467 1.6E-75 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 TIGRFAM TIGR01846 type_I_sec_HlyB: type I secretion system ATPase 26 718 1.5E-259 T 12-10-2018 IPR010132 ATPase, type I secretion system, HlyB GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 Pfam PF00664 ABC transporter transmembrane region 168 436 1.1E-51 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 Pfam PF00005 ABC transporter 500 649 3.2E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 Gene3D G3DSA:3.40.50.300 474 723 7.3E-91 T 12-10-2018 AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 Gene3D G3DSA:3.90.70.10 24 146 8.5E-24 T 12-10-2018 AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 Pfam PF03412 Peptidase C39 family 24 142 6.5E-17 T 12-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 AFE_2693 fc0a7c9e57424994100d49edc265ff0a 724 SMART SM00382 509 695 3.0E-21 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2796 ebdd7b157cd9a89b3100512338278400 226 SUPERFAMILY SSF46785 3 84 4.09E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2796 ebdd7b157cd9a89b3100512338278400 226 Gene3D G3DSA:1.10.10.10 1 85 4.9E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2796 ebdd7b157cd9a89b3100512338278400 226 SMART SM00418 5 84 4.6E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2796 ebdd7b157cd9a89b3100512338278400 226 Pfam PF12840 Helix-turn-helix domain 9 61 8.0E-10 T 12-10-2018 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 294 1.7E-105 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 292 4.5E-13 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 PRINTS PR00151 Porphobilinogen deaminase signature 44 64 1.1E-41 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 PRINTS PR00151 Porphobilinogen deaminase signature 123 140 1.1E-41 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 1.1E-41 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 PRINTS PR00151 Porphobilinogen deaminase signature 75 94 1.1E-41 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 PRINTS PR00151 Porphobilinogen deaminase signature 142 159 1.1E-41 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 Gene3D G3DSA:3.40.190.10 5 215 8.2E-82 T 12-10-2018 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 SUPERFAMILY SSF53850 4 218 6.92E-82 T 12-10-2018 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 294 37.095 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 212 5.8E-77 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 Gene3D G3DSA:3.30.160.40 220 303 8.2E-24 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 PIRSF PIRSF001438 1 306 1.2E-113 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 Gene3D G3DSA:3.40.190.10 99 198 8.2E-82 T 12-10-2018 AFE_3300 4b1da7f47ce731a68daf723193af5c84 306 SUPERFAMILY SSF54782 220 304 4.32E-22 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_0652 af5c6f8f9bfec98fd09ef64e270d59fe 251 SUPERFAMILY SSF69572 5 250 6.8E-80 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AFE_0652 af5c6f8f9bfec98fd09ef64e270d59fe 251 Gene3D G3DSA:3.40.50.720 5 251 1.6E-89 T 12-10-2018 AFE_0652 af5c6f8f9bfec98fd09ef64e270d59fe 251 Pfam PF00899 ThiF family 13 247 1.4E-65 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFE_2088 9d7d37be2301fa060b222b07acffd7b3 335 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 16 326 4.3E-103 T 12-10-2018 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 AFE_2088 9d7d37be2301fa060b222b07acffd7b3 335 SUPERFAMILY SSF51735 141 291 1.61E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2088 9d7d37be2301fa060b222b07acffd7b3 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 133 1.7E-34 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFE_2088 9d7d37be2301fa060b222b07acffd7b3 335 Gene3D G3DSA:3.90.180.10 5 317 2.7E-80 T 12-10-2018 AFE_2088 9d7d37be2301fa060b222b07acffd7b3 335 SUPERFAMILY SSF50129 1 159 2.28E-49 T 12-10-2018 IPR011032 GroES-like superfamily AFE_2088 9d7d37be2301fa060b222b07acffd7b3 335 Gene3D G3DSA:3.40.50.720 147 276 2.7E-80 T 12-10-2018 AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 Gene3D G3DSA:1.10.8.60 504 579 2.2E-14 T 12-10-2018 AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 Pfam PF00158 Sigma-54 interaction domain 333 497 3.8E-63 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 SUPERFAMILY SSF52540 333 571 3.82E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 Gene3D G3DSA:1.10.10.60 595 639 1.0E-10 T 12-10-2018 AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 Gene3D G3DSA:3.30.450.40 2 195 7.9E-24 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 Pfam PF02954 Bacterial regulatory protein, Fis family 598 634 1.6E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 SUPERFAMILY SSF46689 589 638 1.58E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 418 433 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 SMART SM00382 351 495 5.9E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 Gene3D G3DSA:3.40.50.300 319 503 4.0E-60 T 12-10-2018 AFE_0693 1f49c5b8df2f6bab25b783531d99d1ab 643 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 355 368 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFE_0037 f7c6ef9e0374d172aac01786ef12c666 300 Pfam PF03466 LysR substrate binding domain 87 293 2.1E-40 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_0037 f7c6ef9e0374d172aac01786ef12c666 300 Gene3D G3DSA:3.40.190.10 88 287 8.2E-54 T 12-10-2018 AFE_0037 f7c6ef9e0374d172aac01786ef12c666 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0037 f7c6ef9e0374d172aac01786ef12c666 300 Gene3D G3DSA:1.10.10.10 1 82 6.7E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0037 f7c6ef9e0374d172aac01786ef12c666 300 SUPERFAMILY SSF53850 88 295 3.62E-38 T 12-10-2018 AFE_0037 f7c6ef9e0374d172aac01786ef12c666 300 Gene3D G3DSA:3.40.190.10 162 267 8.2E-54 T 12-10-2018 AFE_0037 f7c6ef9e0374d172aac01786ef12c666 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0037 f7c6ef9e0374d172aac01786ef12c666 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0037 f7c6ef9e0374d172aac01786ef12c666 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0037 f7c6ef9e0374d172aac01786ef12c666 300 SUPERFAMILY SSF46785 2 87 5.62E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2752 5438b3e3dc943605e2cc13f155cd5039 223 SMART SM00382 27 221 5.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2752 5438b3e3dc943605e2cc13f155cd5039 223 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 6.2E-85 T 12-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 AFE_2752 5438b3e3dc943605e2cc13f155cd5039 223 Pfam PF00005 ABC transporter 18 165 4.9E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2752 5438b3e3dc943605e2cc13f155cd5039 223 SUPERFAMILY SSF52540 1 219 1.06E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2752 5438b3e3dc943605e2cc13f155cd5039 223 Gene3D G3DSA:3.40.50.300 1 222 1.4E-62 T 12-10-2018 AFE_2752 5438b3e3dc943605e2cc13f155cd5039 223 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2730 4a3be9b60caba516575b9124551395a2 404 SUPERFAMILY SSF81648 203 367 2.09E-40 T 12-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFE_2730 4a3be9b60caba516575b9124551395a2 404 Gene3D G3DSA:1.20.810.10 1 404 1.6E-126 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 AFE_2730 4a3be9b60caba516575b9124551395a2 404 SUPERFAMILY SSF81342 8 265 3.77E-76 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFE_2730 4a3be9b60caba516575b9124551395a2 404 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 276 376 1.0E-32 T 12-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFE_2730 4a3be9b60caba516575b9124551395a2 404 Pfam PF00033 Cytochrome b/b6/petB 23 210 7.3E-50 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFE_0664 8dacebe1a3852e69937c1cbe42235ffb 435 SUPERFAMILY SSF53633 5 287 1.15E-74 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_0664 8dacebe1a3852e69937c1cbe42235ffb 435 SUPERFAMILY SSF55729 256 396 5.32E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_0664 8dacebe1a3852e69937c1cbe42235ffb 435 Gene3D G3DSA:3.40.1160.10 4 287 8.0E-91 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_0664 8dacebe1a3852e69937c1cbe42235ffb 435 Pfam PF00583 Acetyltransferase (GNAT) family 319 396 1.4E-14 T 12-10-2018 IPR000182 GNAT domain AFE_0664 8dacebe1a3852e69937c1cbe42235ffb 435 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 435 189.751 T 12-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 AFE_0664 8dacebe1a3852e69937c1cbe42235ffb 435 Gene3D G3DSA:3.40.630.30 288 435 3.8E-39 T 12-10-2018 AFE_0664 8dacebe1a3852e69937c1cbe42235ffb 435 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 6 435 6.1E-159 T 12-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 AFE_0664 8dacebe1a3852e69937c1cbe42235ffb 435 PIRSF PIRSF000423 1 435 2.8E-172 T 12-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 AFE_0664 8dacebe1a3852e69937c1cbe42235ffb 435 Pfam PF00696 Amino acid kinase family 24 261 8.8E-31 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFE_2764 6bfb02f48281cef7db05a632b6c84c7c 281 SUPERFAMILY SSF54211 4 155 2.81E-39 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_2764 6bfb02f48281cef7db05a632b6c84c7c 281 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 267 31.125 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFE_2764 6bfb02f48281cef7db05a632b6c84c7c 281 Gene3D G3DSA:3.30.70.890 161 279 1.3E-28 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFE_2764 6bfb02f48281cef7db05a632b6c84c7c 281 SUPERFAMILY SSF55060 160 276 1.03E-29 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFE_2764 6bfb02f48281cef7db05a632b6c84c7c 281 Pfam PF08544 GHMP kinases C terminal 209 255 2.1E-4 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain AFE_2764 6bfb02f48281cef7db05a632b6c84c7c 281 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 2 275 4.5E-71 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFE_2764 6bfb02f48281cef7db05a632b6c84c7c 281 Gene3D G3DSA:3.30.230.10 1 157 3.6E-51 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_2764 6bfb02f48281cef7db05a632b6c84c7c 281 PIRSF PIRSF010376 1 278 2.2E-80 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFE_2764 6bfb02f48281cef7db05a632b6c84c7c 281 Pfam PF00288 GHMP kinases N terminal domain 85 142 6.2E-8 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFE_0900 241cede66bb606a0433db4e4b63651f7 301 Gene3D G3DSA:1.10.3660.10 192 296 2.2E-31 T 12-10-2018 AFE_0900 241cede66bb606a0433db4e4b63651f7 301 Pfam PF02153 Prephenate dehydrogenase 31 286 6.3E-59 T 12-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 AFE_0900 241cede66bb606a0433db4e4b63651f7 301 Gene3D G3DSA:3.40.50.720 15 191 1.1E-43 T 12-10-2018 AFE_0900 241cede66bb606a0433db4e4b63651f7 301 SUPERFAMILY SSF51735 18 184 2.4E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0900 241cede66bb606a0433db4e4b63651f7 301 SUPERFAMILY SSF48179 188 294 7.6E-29 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFE_0405 ec024390fc2bc17931beb798073938b6 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 3.1E-28 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFE_0405 ec024390fc2bc17931beb798073938b6 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 3.1E-28 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFE_0405 ec024390fc2bc17931beb798073938b6 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 3.1E-28 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFE_0405 ec024390fc2bc17931beb798073938b6 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 131 142 3.1E-28 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFE_0405 ec024390fc2bc17931beb798073938b6 311 PRINTS PR00102 Ornithine carbamoyltransferase signature 47 61 2.5E-31 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFE_0405 ec024390fc2bc17931beb798073938b6 311 PRINTS PR00102 Ornithine carbamoyltransferase signature 80 93 2.5E-31 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFE_0405 ec024390fc2bc17931beb798073938b6 311 PRINTS PR00102 Ornithine carbamoyltransferase signature 217 227 2.5E-31 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFE_0405 ec024390fc2bc17931beb798073938b6 311 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 2.5E-31 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFE_0405 ec024390fc2bc17931beb798073938b6 311 PRINTS PR00102 Ornithine carbamoyltransferase signature 120 134 2.5E-31 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFE_0405 ec024390fc2bc17931beb798073938b6 311 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 300 3.3E-116 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFE_0405 ec024390fc2bc17931beb798073938b6 311 Gene3D G3DSA:3.40.50.1370 134 296 4.4E-117 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFE_0405 ec024390fc2bc17931beb798073938b6 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 298 3.4E-49 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AFE_0405 ec024390fc2bc17931beb798073938b6 311 Gene3D G3DSA:3.40.50.1370 4 133 4.4E-117 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFE_0405 ec024390fc2bc17931beb798073938b6 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 144 8.7E-52 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AFE_0405 ec024390fc2bc17931beb798073938b6 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFE_0405 ec024390fc2bc17931beb798073938b6 311 SUPERFAMILY SSF53671 2 301 2.49E-104 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFE_0405 ec024390fc2bc17931beb798073938b6 311 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 3 301 79.681 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 Pfam PF01011 PQQ enzyme repeat 139 169 4.0E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 Gene3D G3DSA:2.130.10.10 351 496 4.2E-23 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 Pfam PF13360 PQQ-like domain 213 276 7.8E-9 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 Pfam PF13360 PQQ-like domain 289 493 7.2E-15 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 SUPERFAMILY SSF50998 352 496 1.44E-22 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 Gene3D G3DSA:2.130.10.10 119 346 2.9E-32 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 SUPERFAMILY SSF50998 128 376 4.32E-31 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 SMART SM00564 240 272 14.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 SMART SM00564 134 165 0.1 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 SMART SM00564 385 417 380.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 SMART SM00564 328 370 10.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 SMART SM00564 430 461 10.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_0029 59a704e0fa6d7ebff27e9760e3e7719b 499 SMART SM00564 175 232 13.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_0208 a3fea8a7f1366c9ae0f40c16a65a7283 448 Pfam PF08245 Mur ligase middle domain 111 286 5.0E-29 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFE_0208 a3fea8a7f1366c9ae0f40c16a65a7283 448 Gene3D G3DSA:3.90.190.20 307 439 1.3E-39 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_0208 a3fea8a7f1366c9ae0f40c16a65a7283 448 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 6 443 33.209 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFE_0208 a3fea8a7f1366c9ae0f40c16a65a7283 448 Pfam PF02875 Mur ligase family, glutamate ligase domain 308 374 1.9E-5 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFE_0208 a3fea8a7f1366c9ae0f40c16a65a7283 448 SUPERFAMILY SSF53244 306 443 3.11E-37 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_0208 a3fea8a7f1366c9ae0f40c16a65a7283 448 SUPERFAMILY SSF53623 97 304 3.14E-53 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_0208 a3fea8a7f1366c9ae0f40c16a65a7283 448 Gene3D G3DSA:3.40.1190.10 95 306 3.7E-62 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_0208 a3fea8a7f1366c9ae0f40c16a65a7283 448 SUPERFAMILY SSF51984 1 95 4.71E-16 T 12-10-2018 AFE_0208 a3fea8a7f1366c9ae0f40c16a65a7283 448 Gene3D G3DSA:3.40.50.720 1 94 2.9E-18 T 12-10-2018 AFE_0208 a3fea8a7f1366c9ae0f40c16a65a7283 448 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 8 441 1.2E-119 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFE_0168 94bb25d63b426314046de65d53c1faf6 296 Gene3D G3DSA:3.30.70.1070 207 277 5.8E-6 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 AFE_0168 94bb25d63b426314046de65d53c1faf6 296 Pfam PF05036 Sporulation related domain 204 274 6.4E-9 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 AFE_0168 94bb25d63b426314046de65d53c1faf6 296 SUPERFAMILY SSF110997 206 276 1.14E-10 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 SUPERFAMILY SSF52540 5 221 1.69E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 1.2E-14 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.2E-59 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 SUPERFAMILY SSF50447 207 303 2.36E-31 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 Gene3D G3DSA:2.40.30.10 209 336 6.9E-54 T 12-10-2018 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 5.9E-16 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 Gene3D G3DSA:3.40.50.300 1 205 1.3E-70 T 12-10-2018 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.46 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 SUPERFAMILY SSF50465 300 395 1.93E-36 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 Gene3D G3DSA:2.40.30.10 340 395 1.3E-26 T 12-10-2018 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.8E-34 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 9.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 9.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 9.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 9.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 9.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 1.1E-228 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFE_0325 c6cbd10fa1d01e194008ad05bec9e893 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 SUPERFAMILY SSF52540 5 221 1.69E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 150 1.2E-14 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.2E-59 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 SUPERFAMILY SSF50447 207 303 2.36E-31 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 Gene3D G3DSA:2.40.30.10 209 336 6.9E-54 T 12-10-2018 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 5.9E-16 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 Gene3D G3DSA:3.40.50.300 1 205 1.3E-70 T 12-10-2018 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.46 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 SUPERFAMILY SSF50465 300 395 1.93E-36 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 Gene3D G3DSA:2.40.30.10 340 395 1.3E-26 T 12-10-2018 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 2.8E-34 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 9.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 9.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 9.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 9.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 9.3E-24 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 1.1E-228 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFE_0311 c6cbd10fa1d01e194008ad05bec9e893 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFE_1445 920a1d7440da6923ab7bc64236af2651 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 76 86 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFE_1445 920a1d7440da6923ab7bc64236af2651 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 290 1.1E-98 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFE_1445 920a1d7440da6923ab7bc64236af2651 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 289 71.881 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFE_1445 920a1d7440da6923ab7bc64236af2651 292 SUPERFAMILY SSF54713 55 142 3.4E-20 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFE_1445 920a1d7440da6923ab7bc64236af2651 292 SUPERFAMILY SSF54713 146 290 2.09E-45 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFE_1445 920a1d7440da6923ab7bc64236af2651 292 Gene3D G3DSA:1.10.286.20 189 235 5.5E-38 T 12-10-2018 AFE_1445 920a1d7440da6923ab7bc64236af2651 292 SUPERFAMILY SSF46934 1 55 4.08E-16 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 AFE_1445 920a1d7440da6923ab7bc64236af2651 292 Pfam PF00889 Elongation factor TS 72 271 2.4E-65 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 AFE_1445 920a1d7440da6923ab7bc64236af2651 292 Gene3D G3DSA:3.30.479.20 151 270 5.5E-38 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFE_1445 920a1d7440da6923ab7bc64236af2651 292 Gene3D G3DSA:3.30.479.20 56 144 4.2E-26 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFE_1445 920a1d7440da6923ab7bc64236af2651 292 Gene3D G3DSA:1.10.8.10 1 55 1.2E-23 T 12-10-2018 AFE_1828 98765dde4e73d57c5b61e5457b1c8a1d 188 Pfam PF00877 NlpC/P60 family 70 176 8.2E-29 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFE_1828 98765dde4e73d57c5b61e5457b1c8a1d 188 Gene3D G3DSA:3.90.1720.10 28 171 1.8E-39 T 12-10-2018 AFE_1828 98765dde4e73d57c5b61e5457b1c8a1d 188 SUPERFAMILY SSF54001 59 178 4.91E-39 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFE_1909 eb2ee2aecd42fefaab5250ee7d2e242a 82 SMART SM00823 Phosphopantetheine attachment site 5 77 0.0053 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFE_1909 eb2ee2aecd42fefaab5250ee7d2e242a 82 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 75 7.3E-36 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFE_1909 eb2ee2aecd42fefaab5250ee7d2e242a 82 SUPERFAMILY SSF47336 2 79 6.28E-24 T 12-10-2018 IPR036736 ACP-like superfamily AFE_1909 eb2ee2aecd42fefaab5250ee7d2e242a 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 34 76 0.005 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFE_1909 eb2ee2aecd42fefaab5250ee7d2e242a 82 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.805 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFE_1909 eb2ee2aecd42fefaab5250ee7d2e242a 82 Gene3D G3DSA:1.10.1200.10 1 81 6.4E-31 T 12-10-2018 IPR036736 ACP-like superfamily AFE_1909 eb2ee2aecd42fefaab5250ee7d2e242a 82 Pfam PF00550 Phosphopantetheine attachment site 6 73 5.7E-16 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFE_1909 eb2ee2aecd42fefaab5250ee7d2e242a 82 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site AFE_0379 a51b349f430ce872ac7bc708bb8f04fe 442 Gene3D G3DSA:1.20.272.10 235 339 2.0E-43 T 12-10-2018 AFE_0379 a51b349f430ce872ac7bc708bb8f04fe 442 SMART SM00382 44 160 1.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0379 a51b349f430ce872ac7bc708bb8f04fe 442 Pfam PF12002 MgsA AAA+ ATPase C terminal 262 428 2.6E-67 T 12-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal AFE_0379 a51b349f430ce872ac7bc708bb8f04fe 442 SUPERFAMILY SSF52540 7 219 6.09E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0379 a51b349f430ce872ac7bc708bb8f04fe 442 Gene3D G3DSA:3.40.50.300 1 159 4.0E-42 T 12-10-2018 AFE_0379 a51b349f430ce872ac7bc708bb8f04fe 442 Gene3D G3DSA:1.10.8.60 160 233 1.2E-14 T 12-10-2018 AFE_0379 a51b349f430ce872ac7bc708bb8f04fe 442 SUPERFAMILY SSF48019 246 428 1.19E-73 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFE_0379 a51b349f430ce872ac7bc708bb8f04fe 442 Pfam PF16193 AAA C-terminal domain 184 261 1.3E-20 T 12-10-2018 IPR032423 AAA C-terminal domain AFE_0379 a51b349f430ce872ac7bc708bb8f04fe 442 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 11 133 9.7E-16 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 AFE_0379 a51b349f430ce872ac7bc708bb8f04fe 442 Gene3D G3DSA:1.10.3710.10 340 440 1.8E-32 T 12-10-2018 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 843 4.6E-274 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 Gene3D G3DSA:3.90.740.10 194 406 2.8E-238 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 564 573 2.5E-33 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 2.5E-33 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 2.5E-33 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 236 259 2.5E-33 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 530 543 2.5E-33 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 Gene3D G3DSA:1.10.730.20 643 929 2.3E-88 T 12-10-2018 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 Gene3D G3DSA:3.40.50.620 24 632 2.8E-238 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 SUPERFAMILY SSF47323 655 927 1.85E-71 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 SUPERFAMILY SSF52374 1 650 2.95E-135 T 12-10-2018 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 928 20.731 T 12-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 643 3.0E-195 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 Pfam PF06827 Zinc finger found in FPG and IleRS 897 925 3.3E-7 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 Pfam PF08264 Anticodon-binding domain of tRNA 688 842 2.2E-28 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFE_0556 add8a24f6f287e2606cab846198d4ee0 937 SUPERFAMILY SSF50677 204 401 4.29E-52 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 TIGRFAM TIGR01391 dnaG: DNA primase 5 410 1.3E-132 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 SUPERFAMILY SSF56731 111 414 7.72E-97 T 12-10-2018 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 Pfam PF08275 DNA primase catalytic core, N-terminal domain 125 245 7.4E-37 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 Pfam PF10410 DnaB-helicase binding domain of primase 362 413 4.6E-10 T 12-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 Hamap MF_00974 DNA primase [dnaG]. 3 573 26.79 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 Gene3D G3DSA:3.90.580.10 2 99 9.8E-37 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 SUPERFAMILY SSF57783 1 98 1.05E-34 T 12-10-2018 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 SMART SM00400 35 89 2.1E-33 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 PIRSF PIRSF002811 1 569 1.8E-132 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 Pfam PF01807 CHC2 zinc finger 6 97 6.3E-37 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 SMART SM00493 252 323 2.2E-19 T 12-10-2018 IPR006171 TOPRIM domain AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 Gene3D G3DSA:3.90.980.10 105 233 1.3E-34 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 Pfam PF13155 Toprim-like 256 341 7.2E-14 T 12-10-2018 AFE_2337 f3a6d06be5c1346ade9e8c5e4c985523 583 Gene3D G3DSA:3.40.1360.10 234 360 2.4E-41 T 12-10-2018 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 SUPERFAMILY SSF52343 201 332 1.31E-41 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFE_0252 40b1de64778cf45255c8d3251acad50f 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 245 256 4.6E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 298 306 4.6E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 208 227 4.6E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 132 142 4.6E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 Pfam PF00175 Oxidoreductase NAD-binding domain 209 308 1.2E-24 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 81 6.9E-16 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 SUPERFAMILY SSF54292 1 89 2.1E-28 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 Pfam PF00970 Oxidoreductase FAD-binding domain 107 197 1.8E-12 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 Gene3D G3DSA:2.40.30.10 101 199 3.7E-23 T 12-10-2018 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 Gene3D G3DSA:3.40.50.80 200 333 8.8E-38 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFE_0252 40b1de64778cf45255c8d3251acad50f 338 SUPERFAMILY SSF63380 102 198 1.76E-24 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFE_0252 40b1de64778cf45255c8d3251acad50f 338 Gene3D G3DSA:3.10.20.30 1 99 8.5E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_0252 40b1de64778cf45255c8d3251acad50f 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 233 242 5.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 298 306 5.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 5.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 208 227 5.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 192 201 5.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_0252 40b1de64778cf45255c8d3251acad50f 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 5.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_2748 f499b66c3684bd01eb58ef5666b38b4a 440 SUPERFAMILY SSF52540 3 438 2.22E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2748 f499b66c3684bd01eb58ef5666b38b4a 440 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 332 402 1.3E-4 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFE_2748 f499b66c3684bd01eb58ef5666b38b4a 440 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 440 1.0E-197 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 AFE_2748 f499b66c3684bd01eb58ef5666b38b4a 440 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 440 42.222 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 AFE_2748 f499b66c3684bd01eb58ef5666b38b4a 440 Gene3D G3DSA:1.10.8.60 332 437 1.2E-36 T 12-10-2018 AFE_2748 f499b66c3684bd01eb58ef5666b38b4a 440 SMART SM00382 49 329 5.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2748 f499b66c3684bd01eb58ef5666b38b4a 440 Pfam PF07724 AAA domain (Cdc48 subfamily) 177 326 1.3E-39 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_2748 f499b66c3684bd01eb58ef5666b38b4a 440 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 107 5.0E-7 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_2748 f499b66c3684bd01eb58ef5666b38b4a 440 SMART SM01086 332 428 4.7E-17 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFE_2554 08d82a8313c1ba4e3e0b70bfa4806015 447 Pfam PF02754 Cysteine-rich domain 254 351 8.8E-7 T 12-10-2018 IPR004017 Cysteine-rich domain AFE_0677 34a711aa1990def3fea956f247f87f8b 621 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 336 350 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 SUPERFAMILY SSF53067 200 380 1.91E-50 T 12-10-2018 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 SUPERFAMILY SSF53067 19 197 1.81E-50 T 12-10-2018 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 619 41.642 T 12-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 205 218 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 Pfam PF00012 Hsp70 protein 21 603 9.4E-175 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 Gene3D G3DSA:1.20.1270.10 523 618 8.3E-23 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 SUPERFAMILY SSF100934 507 618 3.73E-28 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 Gene3D G3DSA:2.60.34.10 383 520 5.9E-48 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 618 2.6E-277 T 12-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 Gene3D G3DSA:3.30.420.40 22 378 6.3E-110 T 12-10-2018 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 Gene3D G3DSA:3.90.640.10 238 315 6.3E-110 T 12-10-2018 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 SUPERFAMILY SSF100920 386 539 7.72E-48 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 PRINTS PR00301 70kDa heat shock protein signature 152 172 2.0E-55 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 PRINTS PR00301 70kDa heat shock protein signature 20 33 2.0E-55 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 PRINTS PR00301 70kDa heat shock protein signature 48 60 2.0E-55 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 PRINTS PR00301 70kDa heat shock protein signature 211 221 2.0E-55 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 PRINTS PR00301 70kDa heat shock protein signature 333 349 2.0E-55 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 PRINTS PR00301 70kDa heat shock protein signature 469 485 2.0E-55 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 PRINTS PR00301 70kDa heat shock protein signature 364 384 2.0E-55 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 PRINTS PR00301 70kDa heat shock protein signature 388 407 2.0E-55 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_0677 34a711aa1990def3fea956f247f87f8b 621 Gene3D G3DSA:3.30.420.40 194 365 6.3E-110 T 12-10-2018 AFE_0270 5cf6ad0892be3ddfb02be1b766b396fc 233 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 176 192 2.9E-7 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_0270 5cf6ad0892be3ddfb02be1b766b396fc 233 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 192 207 2.9E-7 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_0270 5cf6ad0892be3ddfb02be1b766b396fc 233 SMART SM00100 18 138 2.5E-15 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFE_0270 5cf6ad0892be3ddfb02be1b766b396fc 233 Gene3D G3DSA:2.60.120.10 34 151 2.2E-27 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_0270 5cf6ad0892be3ddfb02be1b766b396fc 233 SUPERFAMILY SSF51206 11 149 2.62E-25 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFE_0270 5cf6ad0892be3ddfb02be1b766b396fc 233 SMART SM00419 170 218 3.3E-8 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_0270 5cf6ad0892be3ddfb02be1b766b396fc 233 Pfam PF00027 Cyclic nucleotide-binding domain 38 121 7.2E-14 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFE_0270 5cf6ad0892be3ddfb02be1b766b396fc 233 Gene3D G3DSA:1.10.10.10 152 229 4.9E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0270 5cf6ad0892be3ddfb02be1b766b396fc 233 Pfam PF13545 Crp-like helix-turn-helix domain 155 222 4.4E-16 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_0270 5cf6ad0892be3ddfb02be1b766b396fc 233 SUPERFAMILY SSF46785 153 224 1.18E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_3142 c5a1f9a518f3a8bcd7d953d66d819d61 397 Gene3D G3DSA:1.20.1250.20 1 379 8.9E-71 T 12-10-2018 AFE_3142 c5a1f9a518f3a8bcd7d953d66d819d61 397 PRINTS PR01036 Tetracycline resistance protein TetB signature 72 94 5.8E-5 T 12-10-2018 AFE_3142 c5a1f9a518f3a8bcd7d953d66d819d61 397 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 5.8E-5 T 12-10-2018 AFE_3142 c5a1f9a518f3a8bcd7d953d66d819d61 397 Pfam PF07690 Major Facilitator Superfamily 13 288 1.7E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_3142 c5a1f9a518f3a8bcd7d953d66d819d61 397 SUPERFAMILY SSF103473 5 380 5.23E-58 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_0185 e250ed7c20d9275981025ff148104f31 445 SUPERFAMILY SSF52172 4 176 3.98E-39 T 12-10-2018 IPR011006 CheY-like superfamily AFE_0185 e250ed7c20d9275981025ff148104f31 445 Pfam PF02954 Bacterial regulatory protein, Fis family 401 438 3.4E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0185 e250ed7c20d9275981025ff148104f31 445 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 219 234 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFE_0185 e250ed7c20d9275981025ff148104f31 445 Pfam PF00158 Sigma-54 interaction domain 133 299 3.3E-64 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_0185 e250ed7c20d9275981025ff148104f31 445 SUPERFAMILY SSF52540 133 369 1.66E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0185 e250ed7c20d9275981025ff148104f31 445 Pfam PF00072 Response regulator receiver domain 5 113 5.7E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0185 e250ed7c20d9275981025ff148104f31 445 Gene3D G3DSA:3.40.50.300 128 303 5.7E-59 T 12-10-2018 AFE_0185 e250ed7c20d9275981025ff148104f31 445 Gene3D G3DSA:3.40.50.2300 4 127 2.0E-30 T 12-10-2018 AFE_0185 e250ed7c20d9275981025ff148104f31 445 SMART SM00448 2 113 3.3E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0185 e250ed7c20d9275981025ff148104f31 445 Gene3D G3DSA:1.10.8.60 304 378 1.1E-15 T 12-10-2018 AFE_0185 e250ed7c20d9275981025ff148104f31 445 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 346 355 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_0185 e250ed7c20d9275981025ff148104f31 445 SMART SM00382 153 296 6.5E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0185 e250ed7c20d9275981025ff148104f31 445 SUPERFAMILY SSF46689 347 438 1.39E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_0474 43e132a8c0c7d1fd0756c98ffd0d04bd 376 PIRSF PIRSF038945 1 375 2.7E-153 T 12-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 AFE_0474 43e132a8c0c7d1fd0756c98ffd0d04bd 376 Gene3D G3DSA:3.40.50.1100 14 350 1.9E-115 T 12-10-2018 AFE_0474 43e132a8c0c7d1fd0756c98ffd0d04bd 376 Gene3D G3DSA:3.40.50.1100 62 158 1.9E-115 T 12-10-2018 AFE_0474 43e132a8c0c7d1fd0756c98ffd0d04bd 376 TIGRFAM TIGR00260 thrC: threonine synthase 9 350 3.2E-88 T 12-10-2018 IPR004450 Threonine synthase-like AFE_0474 43e132a8c0c7d1fd0756c98ffd0d04bd 376 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 54 67 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AFE_0474 43e132a8c0c7d1fd0756c98ffd0d04bd 376 SUPERFAMILY SSF53686 6 375 7.33E-97 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFE_0474 43e132a8c0c7d1fd0756c98ffd0d04bd 376 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 343 9.0E-66 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFE_0455 65852a3d8c7d573d32bb684ea5aad159 394 SUPERFAMILY SSF103473 8 387 4.71E-48 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_0455 65852a3d8c7d573d32bb684ea5aad159 394 PRINTS PR01035 Tetracycline resistance protein signature 274 295 1.0E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFE_0455 65852a3d8c7d573d32bb684ea5aad159 394 PRINTS PR01035 Tetracycline resistance protein signature 335 358 1.0E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFE_0455 65852a3d8c7d573d32bb684ea5aad159 394 PRINTS PR01035 Tetracycline resistance protein signature 136 158 1.0E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFE_0455 65852a3d8c7d573d32bb684ea5aad159 394 PRINTS PR01035 Tetracycline resistance protein signature 18 34 1.0E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFE_0455 65852a3d8c7d573d32bb684ea5aad159 394 Gene3D G3DSA:1.20.1250.20 7 254 1.5E-20 T 12-10-2018 AFE_0455 65852a3d8c7d573d32bb684ea5aad159 394 ProSitePatterns PS00216 Sugar transport proteins signature 1. 265 281 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFE_0455 65852a3d8c7d573d32bb684ea5aad159 394 Pfam PF07690 Major Facilitator Superfamily 13 250 4.1E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_0455 65852a3d8c7d573d32bb684ea5aad159 394 Pfam PF07690 Major Facilitator Superfamily 263 390 2.3E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_0455 65852a3d8c7d573d32bb684ea5aad159 394 Gene3D G3DSA:1.20.1720.10 259 393 4.1E-14 T 12-10-2018 AFE_2572 c60c7919af22e1312b54ad3a910781de 348 SUPERFAMILY SSF141523 82 217 2.88E-24 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFE_2572 c60c7919af22e1312b54ad3a910781de 348 Gene3D G3DSA:2.40.440.10 9 290 1.8E-69 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFE_2572 c60c7919af22e1312b54ad3a910781de 348 Pfam PF03734 L,D-transpeptidase catalytic domain 84 217 4.7E-16 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 860 0.0 T 12-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 Gene3D G3DSA:3.40.50.300 555 769 1.1E-88 T 12-10-2018 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 Gene3D G3DSA:3.40.50.300 343 549 2.5E-68 T 12-10-2018 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 Gene3D G3DSA:1.10.8.60 771 865 1.3E-25 T 12-10-2018 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 771 851 2.1E-24 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFE_1970 070d71a0936ea8bf58f32120ef376567 866 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 636 654 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 4.7E-15 T 12-10-2018 IPR004176 Clp, N-terminal AFE_1970 070d71a0936ea8bf58f32120ef376567 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 142 1.2E-14 T 12-10-2018 IPR004176 Clp, N-terminal AFE_1970 070d71a0936ea8bf58f32120ef376567 866 SMART SM01086 771 860 1.3E-34 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFE_1970 070d71a0936ea8bf58f32120ef376567 866 SUPERFAMILY SSF52540 551 858 7.38E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1970 070d71a0936ea8bf58f32120ef376567 866 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 Gene3D G3DSA:3.40.50.300 147 342 7.2E-73 T 12-10-2018 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 Gene3D G3DSA:1.10.1780.10 1 146 5.9E-37 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 Pfam PF07724 AAA domain (Cdc48 subfamily) 601 764 8.2E-56 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 SUPERFAMILY SSF81923 4 141 3.63E-44 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 336 7.0E-12 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 713 727 2.8E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 680 698 2.8E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 651 669 2.8E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 606 624 2.8E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFE_1970 070d71a0936ea8bf58f32120ef376567 866 SUPERFAMILY SSF52540 159 550 8.31E-97 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1970 070d71a0936ea8bf58f32120ef376567 866 SMART SM00382 198 343 1.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1970 070d71a0936ea8bf58f32120ef376567 866 SMART SM00382 602 757 9.3E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0184 e4e6af038789582f624ec065633d8855 530 SMART SM00387 413 523 3.0E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0184 e4e6af038789582f624ec065633d8855 530 Gene3D G3DSA:3.30.565.10 398 526 7.0E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0184 e4e6af038789582f624ec065633d8855 530 Gene3D G3DSA:1.10.287.130 294 369 1.3E-16 T 12-10-2018 AFE_0184 e4e6af038789582f624ec065633d8855 530 Pfam PF00512 His Kinase A (phospho-acceptor) domain 306 367 2.9E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0184 e4e6af038789582f624ec065633d8855 530 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 482 4.3E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0184 e4e6af038789582f624ec065633d8855 530 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 468 4.3E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0184 e4e6af038789582f624ec065633d8855 530 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 501 4.3E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0184 e4e6af038789582f624ec065633d8855 530 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 520 4.3E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0184 e4e6af038789582f624ec065633d8855 530 SUPERFAMILY SSF55874 365 521 2.13E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0184 e4e6af038789582f624ec065633d8855 530 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 414 521 9.4E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0184 e4e6af038789582f624ec065633d8855 530 SUPERFAMILY SSF47384 296 368 3.53E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_0184 e4e6af038789582f624ec065633d8855 530 SMART SM00388 306 371 4.4E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0020 1038555ba3369d8fabea2cf92e5f90cb 313 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 307 34.977 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 AFE_0020 1038555ba3369d8fabea2cf92e5f90cb 313 Pfam PF02911 Formyl transferase, C-terminal domain 207 305 1.3E-24 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFE_0020 1038555ba3369d8fabea2cf92e5f90cb 313 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 6 311 3.5E-94 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 AFE_0020 1038555ba3369d8fabea2cf92e5f90cb 313 Pfam PF00551 Formyl transferase 6 183 7.5E-42 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFE_0020 1038555ba3369d8fabea2cf92e5f90cb 313 Gene3D G3DSA:3.10.25.10 210 313 2.7E-28 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFE_0020 1038555ba3369d8fabea2cf92e5f90cb 313 Gene3D G3DSA:3.40.50.170 1 209 1.6E-76 T 12-10-2018 AFE_0020 1038555ba3369d8fabea2cf92e5f90cb 313 SUPERFAMILY SSF50486 208 312 8.63E-31 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 AFE_0020 1038555ba3369d8fabea2cf92e5f90cb 313 SUPERFAMILY SSF53328 6 210 5.49E-63 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 188 489 1.8E-121 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 497 36.535 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 PRINTS PR00481 Cytosol aminopeptidase signature 286 307 3.2E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 PRINTS PR00481 Cytosol aminopeptidase signature 323 344 3.2E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 PRINTS PR00481 Cytosol aminopeptidase signature 264 281 3.2E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 PRINTS PR00481 Cytosol aminopeptidase signature 373 388 3.2E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 PRINTS PR00481 Cytosol aminopeptidase signature 345 365 3.2E-48 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 145 3.3E-23 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 349 356 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 Gene3D G3DSA:3.40.630.10 183 497 1.7E-133 T 12-10-2018 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 Gene3D G3DSA:3.40.220.10 1 160 1.7E-41 T 12-10-2018 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 SUPERFAMILY SSF53187 182 495 4.08E-119 T 12-10-2018 AFE_2201 c97c13e3a37a4a5b6c4156388a82be25 500 SUPERFAMILY SSF52949 2 185 7.65E-32 T 12-10-2018 AFE_1563 0eea1f3ec22fe3d108dce4c47aa6f58a 164 Gene3D G3DSA:1.10.260.40 13 88 3.3E-21 T 12-10-2018 AFE_1563 0eea1f3ec22fe3d108dce4c47aa6f58a 164 SMART SM00530 23 80 6.4E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_1563 0eea1f3ec22fe3d108dce4c47aa6f58a 164 Pfam PF01381 Helix-turn-helix 30 80 5.1E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_1563 0eea1f3ec22fe3d108dce4c47aa6f58a 164 SUPERFAMILY SSF47413 14 87 1.13E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_3164 b29141456cf30a81399a16443cd0fa37 215 SUPERFAMILY SSF52540 6 201 2.77E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3164 b29141456cf30a81399a16443cd0fa37 215 Gene3D G3DSA:3.40.50.300 1 211 2.3E-39 T 12-10-2018 AFE_3164 b29141456cf30a81399a16443cd0fa37 215 SMART SM00382 25 204 2.5E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_3164 b29141456cf30a81399a16443cd0fa37 215 Pfam PF00005 ABC transporter 28 157 7.2E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0690 f244ebbed45fd4dd48e1d71e70e61c94 285 Gene3D G3DSA:3.10.20.10 34 119 4.1E-12 T 12-10-2018 AFE_0690 f244ebbed45fd4dd48e1d71e70e61c94 285 Gene3D G3DSA:3.40.140.10 129 279 7.4E-43 T 12-10-2018 AFE_0690 f244ebbed45fd4dd48e1d71e70e61c94 285 Pfam PF02634 FdhD/NarQ family 33 270 9.2E-66 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFE_0690 f244ebbed45fd4dd48e1d71e70e61c94 285 SUPERFAMILY SSF53927 23 270 4.21E-66 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFE_0690 f244ebbed45fd4dd48e1d71e70e61c94 285 PIRSF PIRSF015626 8 274 3.4E-66 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFE_0690 f244ebbed45fd4dd48e1d71e70e61c94 285 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 13 271 30.029 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFE_0690 f244ebbed45fd4dd48e1d71e70e61c94 285 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 28 271 1.5E-51 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFE_0782 42d031dcbfeaeafd3032260d41241a06 465 Gene3D G3DSA:3.90.1300.10 10 456 3.7E-134 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFE_0782 42d031dcbfeaeafd3032260d41241a06 465 SUPERFAMILY SSF75304 10 454 2.09E-128 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFE_0782 42d031dcbfeaeafd3032260d41241a06 465 TIGRFAM TIGR02715 amido_AtzE: amidohydrolase, AtzE family 11 458 5.5E-207 T 12-10-2018 IPR014087 Amidohydrolase, AtzE type KEGG: 00791+3.5.1.84|MetaCyc: PWY-5169 AFE_0782 42d031dcbfeaeafd3032260d41241a06 465 Pfam PF01425 Amidase 27 446 2.8E-98 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PIRSF PIRSF000350 1 429 7.5E-59 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 Gene3D G3DSA:3.30.390.30 344 462 2.6E-20 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 324 7.8E-45 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 453 2.4E-15 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 1.4E-28 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 1.4E-28 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 136 154 1.4E-28 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 1.4E-28 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.4E-28 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 SUPERFAMILY SSF55424 341 457 9.97E-21 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 Gene3D G3DSA:3.50.50.60 6 331 4.3E-80 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 SUPERFAMILY SSF51905 1 334 9.86E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 Gene3D G3DSA:3.50.50.60 148 268 4.3E-80 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 139 148 8.8E-50 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 8.8E-50 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 8.8E-50 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 8.8E-50 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 8.8E-50 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 8.8E-50 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 8.8E-50 T 12-10-2018 AFE_0958 b5067a55d86b243ba2396679611e3aa9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 8.8E-50 T 12-10-2018 AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 PRINTS PR01755 Bacterial translocase SecF protein signature 222 240 1.3E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 PRINTS PR01755 Bacterial translocase SecF protein signature 254 269 1.3E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 PRINTS PR01755 Bacterial translocase SecF protein signature 174 188 1.3E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 PRINTS PR01755 Bacterial translocase SecF protein signature 58 73 1.3E-31 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 31 317 29.82 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 SUPERFAMILY SSF82866 94 317 4.05E-40 T 12-10-2018 AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 139 303 1.6E-54 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 Pfam PF07549 SecD/SecF GG Motif 55 79 4.3E-9 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 59 306 1.7E-78 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 Pfam PF02355 Protein export membrane protein 138 314 2.5E-67 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial AFE_2056 81380176f1e7ed387b8b262f9b3881ae 337 Gene3D G3DSA:1.20.1640.10 120 324 1.4E-9 T 12-10-2018 AFE_1793 fbd9eeb93ce89693c31f231fb94a9c9f 292 SUPERFAMILY SSF55120 67 227 6.33E-40 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_1793 fbd9eeb93ce89693c31f231fb94a9c9f 292 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 105 119 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFE_1793 fbd9eeb93ce89693c31f231fb94a9c9f 292 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 71 230 2.2E-51 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFE_1793 fbd9eeb93ce89693c31f231fb94a9c9f 292 Gene3D G3DSA:3.10.290.10 1 57 2.2E-20 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFE_1793 fbd9eeb93ce89693c31f231fb94a9c9f 292 Pfam PF01479 S4 domain 4 48 4.4E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_1793 fbd9eeb93ce89693c31f231fb94a9c9f 292 Pfam PF00849 RNA pseudouridylate synthase 68 200 5.1E-15 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_1793 fbd9eeb93ce89693c31f231fb94a9c9f 292 Gene3D G3DSA:3.30.70.1560 129 219 5.5E-49 T 12-10-2018 AFE_1793 fbd9eeb93ce89693c31f231fb94a9c9f 292 Gene3D G3DSA:3.30.70.580 70 225 5.5E-49 T 12-10-2018 AFE_1793 fbd9eeb93ce89693c31f231fb94a9c9f 292 SMART SM00363 3 66 3.3E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_1793 fbd9eeb93ce89693c31f231fb94a9c9f 292 SUPERFAMILY SSF55174 5 96 5.89E-18 T 12-10-2018 AFE_3240 f78512f639ee2911b5924c0d9cca5b7b 175 SUPERFAMILY SSF46785 16 145 2.54E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_3240 f78512f639ee2911b5924c0d9cca5b7b 175 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 62 80 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site AFE_3240 f78512f639ee2911b5924c0d9cca5b7b 175 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 14 144 3.4E-32 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type AFE_3240 f78512f639ee2911b5924c0d9cca5b7b 175 Pfam PF02082 Transcriptional regulator 14 96 1.3E-20 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type AFE_3240 f78512f639ee2911b5924c0d9cca5b7b 175 Gene3D G3DSA:1.10.10.10 14 151 4.1E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1507 c241d946e5e384fb27a087f3cd8e47fc 402 Gene3D G3DSA:1.10.260.50 15 280 4.4E-139 T 12-10-2018 AFE_1507 c241d946e5e384fb27a087f3cd8e47fc 402 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 5 384 1.4E-192 T 12-10-2018 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFE_1507 c241d946e5e384fb27a087f3cd8e47fc 402 SUPERFAMILY SSF53383 5 370 7.4E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_1507 c241d946e5e384fb27a087f3cd8e47fc 402 Pfam PF00266 Aminotransferase class-V 5 365 2.5E-89 T 12-10-2018 IPR000192 Aminotransferase class V domain AFE_1507 c241d946e5e384fb27a087f3cd8e47fc 402 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AFE_1507 c241d946e5e384fb27a087f3cd8e47fc 402 PIRSF PIRSF005572 1 382 1.3E-129 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFE_1507 c241d946e5e384fb27a087f3cd8e47fc 402 Gene3D G3DSA:3.90.1150.10 5 369 4.4E-139 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_1507 c241d946e5e384fb27a087f3cd8e47fc 402 Gene3D G3DSA:3.40.640.10 61 236 4.4E-139 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 12 494 42.653 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 376 392 5.1E-37 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 234 247 5.1E-37 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 252 269 5.1E-37 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 189 199 5.1E-37 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 205 221 5.1E-37 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 Pfam PF01336 OB-fold nucleic acid binding domain 61 136 3.1E-15 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 Pfam PF00152 tRNA synthetases class II (D, K and N) 153 491 1.3E-76 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 494 1.0E-192 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 Gene3D G3DSA:2.40.50.140 6 144 4.0E-42 T 12-10-2018 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 SUPERFAMILY SSF50249 4 145 2.45E-44 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 Gene3D G3DSA:3.30.930.10 145 489 1.1E-124 T 12-10-2018 AFE_0480 e7371cab4ecfa6f01cb8272e6e628ffa 496 SUPERFAMILY SSF55681 152 492 3.32E-114 T 12-10-2018 AFE_0430 1851303636258c08fcdbed6990c9ef0e 251 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 235 32.084 T 12-10-2018 IPR017689 Outer membrane protein assembly factor BamD AFE_0430 1851303636258c08fcdbed6990c9ef0e 251 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 4 240 3.3E-77 T 12-10-2018 IPR017689 Outer membrane protein assembly factor BamD AFE_0430 1851303636258c08fcdbed6990c9ef0e 251 Gene3D G3DSA:1.25.40.10 33 242 1.4E-48 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0430 1851303636258c08fcdbed6990c9ef0e 251 Pfam PF13525 Outer membrane lipoprotein 34 227 1.0E-52 T 12-10-2018 IPR039565 Outer membrane lipoprotein BamD-like AFE_0430 1851303636258c08fcdbed6990c9ef0e 251 SUPERFAMILY SSF48452 29 140 5.93E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 18 639 48.502 T 12-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 SUPERFAMILY SSF52540 315 640 3.36E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 SMART SM00382 192 441 9.6E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 Gene3D G3DSA:1.10.10.1020 4 132 7.2E-17 T 12-10-2018 AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 SUPERFAMILY SSF52540 8 347 5.02E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 Gene3D G3DSA:3.40.50.300 516 630 2.6E-25 T 12-10-2018 AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 Gene3D G3DSA:3.40.50.300 394 515 1.5E-13 T 12-10-2018 AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 Pfam PF13538 UvrD-like helicase C-terminal domain 570 614 1.3E-15 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 9 640 3.0E-166 T 12-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 Pfam PF13245 AAA domain 183 337 3.6E-28 T 12-10-2018 AFE_2933 b8e469b60765d4005ba5543c8c57da8f 646 Gene3D G3DSA:3.40.50.300 133 374 7.7E-64 T 12-10-2018 AFE_2218 5bfecaafa940896b1b197f7c67fba36f 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 186 5.1E-26 T 12-10-2018 AFE_2218 5bfecaafa940896b1b197f7c67fba36f 227 Gene3D G3DSA:3.40.50.1000 11 207 2.1E-43 T 12-10-2018 IPR023214 HAD superfamily AFE_2218 5bfecaafa940896b1b197f7c67fba36f 227 SUPERFAMILY SSF56784 9 219 1.73E-50 T 12-10-2018 IPR036412 HAD-like superfamily AFE_2218 5bfecaafa940896b1b197f7c67fba36f 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 184 6.2E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_2218 5bfecaafa940896b1b197f7c67fba36f 227 Gene3D G3DSA:1.10.150.240 23 87 2.1E-43 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFE_2071 719c7569256aec265f95ab1b449e6c47 271 Gene3D G3DSA:3.30.70.660 114 249 1.7E-48 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 AFE_2071 719c7569256aec265f95ab1b449e6c47 271 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 252 34.675 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2071 719c7569256aec265f95ab1b449e6c47 271 Pfam PF01416 tRNA pseudouridine synthase 17 111 2.3E-7 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2071 719c7569256aec265f95ab1b449e6c47 271 Pfam PF01416 tRNA pseudouridine synthase 151 253 8.6E-29 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2071 719c7569256aec265f95ab1b449e6c47 271 Gene3D G3DSA:3.30.70.580 7 113 1.2E-35 T 12-10-2018 AFE_2071 719c7569256aec265f95ab1b449e6c47 271 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 13 246 5.4E-63 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2071 719c7569256aec265f95ab1b449e6c47 271 SUPERFAMILY SSF55120 10 258 1.58E-86 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2071 719c7569256aec265f95ab1b449e6c47 271 PIRSF PIRSF001430 9 265 1.1E-74 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 Gene3D G3DSA:3.40.50.300 12 190 5.9E-42 T 12-10-2018 AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 Pfam PF01926 50S ribosome-binding GTPase 18 131 7.3E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 18 38 3.3E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 67 82 3.3E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 SUPERFAMILY SSF54814 188 303 2.68E-35 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 TIGRFAM TIGR00436 era: GTP-binding protein Era 16 285 5.0E-71 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 Gene3D G3DSA:3.30.300.20 192 304 9.3E-35 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 18 174 3.8E-24 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 SUPERFAMILY SSF52540 18 211 1.93E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 Hamap MF_00367 GTPase Era [era]. 13 302 32.687 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1401 75c64c6d8549078a93df3ca18fef98e2 304 Pfam PF07650 KH domain 217 290 4.9E-10 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 SUPERFAMILY SSF54810 394 514 5.1E-52 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 PRINTS PR00097 Anthranilate synthase component II signature 5 19 4.8E-6 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 PRINTS PR00097 Anthranilate synthase component II signature 49 58 4.8E-6 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 PRINTS PR00097 Anthranilate synthase component II signature 167 180 4.8E-6 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 PRINTS PR00097 Anthranilate synthase component II signature 76 87 4.8E-6 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 Pfam PF00117 Glutamine amidotransferase class-I 7 188 1.8E-35 T 12-10-2018 IPR017926 Glutamine amidotransferase AFE_1778 ff6d2ba5e059a22306f1675514749939 514 Gene3D G3DSA:3.40.50.880 1 195 5.4E-50 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_1778 ff6d2ba5e059a22306f1675514749939 514 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 5 19 1.1E-5 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 1.1E-5 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 76 92 1.1E-5 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 194 2.8E-68 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 514 4.3E-149 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 PRINTS PR00096 Glutamine amidotransferase superfamily signature 76 87 1.6E-6 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 PRINTS PR00096 Glutamine amidotransferase superfamily signature 167 180 1.6E-6 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 1.6E-6 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 Gene3D G3DSA:3.30.300.10 395 514 3.6E-54 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 Gene3D G3DSA:3.40.50.620 199 394 1.2E-74 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_1778 ff6d2ba5e059a22306f1675514749939 514 SUPERFAMILY SSF52402 187 408 1.12E-56 T 12-10-2018 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 SUPERFAMILY SSF52317 2 227 1.43E-54 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_1778 ff6d2ba5e059a22306f1675514749939 514 Pfam PF00958 GMP synthase C terminal domain 422 513 1.0E-45 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFE_1778 ff6d2ba5e059a22306f1675514749939 514 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 514 54.17 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 AFE_1911 5fe771ee825828ee1b288378ca3457c6 277 SUPERFAMILY SSF56752 15 270 8.37E-54 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 AFE_1911 5fe771ee825828ee1b288378ca3457c6 277 Gene3D G3DSA:3.30.470.10 10 109 7.9E-25 T 12-10-2018 AFE_1911 5fe771ee825828ee1b288378ca3457c6 277 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 15 248 2.7E-55 T 12-10-2018 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 AFE_1911 5fe771ee825828ee1b288378ca3457c6 277 ProSitePatterns PS00770 Aminotransferases class-IV signature. 174 203 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 AFE_1911 5fe771ee825828ee1b288378ca3457c6 277 Gene3D G3DSA:3.20.10.10 115 271 9.5E-40 T 12-10-2018 AFE_1911 5fe771ee825828ee1b288378ca3457c6 277 Pfam PF01063 Amino-transferase class IV 24 246 1.9E-37 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 AFE_3016 33bded9fc7c186a0894ad02841cede95 530 Pfam PF00884 Sulfatase 222 458 4.2E-19 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 AFE_3016 33bded9fc7c186a0894ad02841cede95 530 SUPERFAMILY SSF53649 222 441 3.05E-17 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFE_3016 33bded9fc7c186a0894ad02841cede95 530 Gene3D G3DSA:3.40.720.10 219 477 2.8E-31 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_3224 7dc26c773fabca12ef6241f851fc9025 290 Gene3D G3DSA:2.60.120.10 28 285 1.0E-97 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_3224 7dc26c773fabca12ef6241f851fc9025 290 Pfam PF02678 Pirin 32 132 1.5E-35 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 AFE_3224 7dc26c773fabca12ef6241f851fc9025 290 PIRSF PIRSF006232 13 290 7.6E-101 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 AFE_3224 7dc26c773fabca12ef6241f851fc9025 290 Gene3D G3DSA:2.60.120.10 154 259 1.0E-97 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_3224 7dc26c773fabca12ef6241f851fc9025 290 SUPERFAMILY SSF51182 15 288 1.36E-85 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_3224 7dc26c773fabca12ef6241f851fc9025 290 Pfam PF05726 Pirin C-terminal cupin domain 187 289 2.2E-29 T 12-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 AFE_2558 7f4e8250b8cd795fb1bde9d2258fb28e 109 SMART SM00450 8 103 3.0E-20 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_2558 7f4e8250b8cd795fb1bde9d2258fb28e 109 Pfam PF00581 Rhodanese-like domain 8 98 6.0E-16 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_2558 7f4e8250b8cd795fb1bde9d2258fb28e 109 SUPERFAMILY SSF52821 2 106 2.49E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_2558 7f4e8250b8cd795fb1bde9d2258fb28e 109 Gene3D G3DSA:3.40.250.10 2 107 7.6E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_3062 6213ce950a9ee03d31bb67ab28e7f10d 185 SUPERFAMILY SSF143456 5 185 5.49E-62 T 12-10-2018 AFE_3062 6213ce950a9ee03d31bb67ab28e7f10d 185 Gene3D G3DSA:3.40.1740.10 1 185 1.7E-66 T 12-10-2018 AFE_3062 6213ce950a9ee03d31bb67ab28e7f10d 185 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 4 185 35.584 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 AFE_3062 6213ce950a9ee03d31bb67ab28e7f10d 185 Pfam PF02622 Uncharacterized ACR, COG1678 15 172 2.9E-46 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 AFE_1546 ed927f590c9052f8c1ec3ca65c6b188a 475 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFE_1546 ed927f590c9052f8c1ec3ca65c6b188a 475 Gene3D G3DSA:3.40.605.10 19 464 7.0E-167 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFE_1546 ed927f590c9052f8c1ec3ca65c6b188a 475 SUPERFAMILY SSF53720 5 472 3.27E-156 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFE_1546 ed927f590c9052f8c1ec3ca65c6b188a 475 Gene3D G3DSA:3.40.309.10 255 441 7.0E-167 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFE_1546 ed927f590c9052f8c1ec3ca65c6b188a 475 Pfam PF00171 Aldehyde dehydrogenase family 19 469 2.6E-157 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFE_2369 76c51e311ac71ca9097ec6d13ebec439 100 Pfam PF01022 Bacterial regulatory protein, arsR family 23 67 5.6E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2369 76c51e311ac71ca9097ec6d13ebec439 100 SMART SM00418 16 94 4.2E-23 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2369 76c51e311ac71ca9097ec6d13ebec439 100 Gene3D G3DSA:1.10.10.10 1 96 2.3E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2369 76c51e311ac71ca9097ec6d13ebec439 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 5.8E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2369 76c51e311ac71ca9097ec6d13ebec439 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 5.8E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2369 76c51e311ac71ca9097ec6d13ebec439 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 48 5.8E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2369 76c51e311ac71ca9097ec6d13ebec439 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 5.8E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2369 76c51e311ac71ca9097ec6d13ebec439 100 SUPERFAMILY SSF46785 5 97 1.88E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1551 bb400e784ec285f893c7553139e43d92 714 Pfam PF00862 Sucrose synthase 9 211 4.8E-12 T 12-10-2018 IPR000368 Sucrose synthase GO:0005985|GO:0016157 AFE_1551 bb400e784ec285f893c7553139e43d92 714 Gene3D G3DSA:3.40.50.2000 224 431 1.1E-133 T 12-10-2018 AFE_1551 bb400e784ec285f893c7553139e43d92 714 TIGRFAM TIGR02471 sucr_syn_bact_C: sucrose-phosphate synthase, sucrose phosphatase-like domain 474 708 6.9E-87 T 12-10-2018 IPR012821 Sucrose phosphate synthase, sucrose phosphatase-like domain AFE_1551 bb400e784ec285f893c7553139e43d92 714 Pfam PF00534 Glycosyl transferases group 1 251 420 1.0E-21 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1551 bb400e784ec285f893c7553139e43d92 714 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 474 664 1.7E-16 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 AFE_1551 bb400e784ec285f893c7553139e43d92 714 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 473 708 7.8E-78 T 12-10-2018 IPR006380 Sucrose-phosphatase-like, N-terminal AFE_1551 bb400e784ec285f893c7553139e43d92 714 Gene3D G3DSA:3.40.50.1000 474 705 4.6E-71 T 12-10-2018 IPR023214 HAD superfamily AFE_1551 bb400e784ec285f893c7553139e43d92 714 SUPERFAMILY SSF53756 21 447 4.32E-62 T 12-10-2018 AFE_1551 bb400e784ec285f893c7553139e43d92 714 TIGRFAM TIGR02472 sucr_P_syn_N: sucrose-phosphate synthase, putative, glycosyltransferase domain 7 443 3.0E-177 T 12-10-2018 IPR012822 Sucrose-phosphate synthase, glycosyltransferase domain AFE_1551 bb400e784ec285f893c7553139e43d92 714 SUPERFAMILY SSF56784 474 680 1.21E-25 T 12-10-2018 IPR036412 HAD-like superfamily AFE_1551 bb400e784ec285f893c7553139e43d92 714 Gene3D G3DSA:3.40.50.2000 28 437 1.1E-133 T 12-10-2018 AFE_1551 bb400e784ec285f893c7553139e43d92 714 Gene3D G3DSA:3.90.1070.10 559 628 4.6E-71 T 12-10-2018 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 SMART SM01350 173 306 3.3E-6 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 PIRSF PIRSF000103 1 299 7.7E-34 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 162 190 4.3E-39 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 63 92 4.3E-39 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 116 141 4.3E-39 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 238 265 4.3E-39 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 4.3E-39 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 SUPERFAMILY SSF48179 171 303 1.29E-39 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 Gene3D G3DSA:1.10.1040.10 172 304 2.3E-49 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 SUPERFAMILY SSF51735 4 160 2.08E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 160 1.8E-41 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 6 305 6.8E-107 T 12-10-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 Gene3D G3DSA:3.40.50.720 1 171 8.6E-53 T 12-10-2018 AFE_2024 40ca1ae2570df4203fd8b684c1de06b3 306 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 173 284 2.4E-24 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 Gene3D G3DSA:3.40.50.300 4 279 4.1E-67 T 12-10-2018 AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 ProSitePatterns PS00746 NifH/frxC family signature 1. 90 102 - T 12-10-2018 IPR030655 NifH/chlL conserved site AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 Hamap MF_00533 Nitrogenase iron protein [nifH]. 5 278 52.477 T 12-10-2018 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 PIRSF PIRSF000363 4 280 6.2E-120 T 12-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 PRINTS PR00091 Nitrogenase component II signature 11 24 9.5E-38 T 12-10-2018 AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 PRINTS PR00091 Nitrogenase component II signature 88 102 9.5E-38 T 12-10-2018 AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 PRINTS PR00091 Nitrogenase component II signature 33 48 9.5E-38 T 12-10-2018 AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 PRINTS PR00091 Nitrogenase component II signature 126 141 9.5E-38 T 12-10-2018 AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 SUPERFAMILY SSF52540 6 282 8.59E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 ProSitePatterns PS00692 NifH/frxC family signature 2. 127 140 - T 12-10-2018 IPR030655 NifH/chlL conserved site AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 6 277 6.0E-134 T 12-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 AFE_1522 ab8488a05c73c9b27da464cbac60bb4c 296 TIGRFAM TIGR01287 nifH: nitrogenase iron protein 6 278 5.6E-139 T 12-10-2018 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 Gene3D G3DSA:1.10.290.10 284 409 4.4E-150 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 SMART SM00493 1 132 1.7E-22 T 12-10-2018 IPR006171 TOPRIM domain AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 SMART SM00437 275 552 1.8E-69 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 Pfam PF01131 DNA topoisomerase 159 585 9.0E-117 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 Pfam PF01751 Toprim domain 3 128 4.9E-15 T 12-10-2018 IPR006171 TOPRIM domain AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 Gene3D G3DSA:3.40.50.140 1 160 4.8E-53 T 12-10-2018 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 515 529 5.4E-25 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 395 411 5.4E-25 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 194 212 5.4E-25 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 106 119 5.4E-25 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 318 327 5.4E-25 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 SMART SM00436 132 224 1.3E-27 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 655 3.9E-191 T 12-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 Gene3D G3DSA:2.70.20.10 218 482 4.4E-150 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 Gene3D G3DSA:1.10.460.10 166 596 4.4E-150 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFE_1738 6bebcc8295be88b7b8576e3549fc1741 699 SUPERFAMILY SSF56712 1 600 2.49E-166 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 SMART SM00493 3 103 2.0E-27 T 12-10-2018 IPR006171 TOPRIM domain AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 623 2.7E-242 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Gene3D G3DSA:3.40.50.140 1 138 2.6E-50 T 12-10-2018 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 SMART SM00436 108 196 1.9E-50 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 SUPERFAMILY SSF57783 628 671 7.82E-12 T 12-10-2018 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 303 312 1.2E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 1.2E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 166 184 1.2E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 381 397 1.2E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 486 500 1.2E-35 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Pfam PF01751 Toprim domain 4 117 1.1E-25 T 12-10-2018 IPR006171 TOPRIM domain AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Gene3D G3DSA:1.10.290.10 261 396 8.2E-167 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 702 53.282 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 SUPERFAMILY SSF56712 4 601 2.22E-189 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Pfam PF01131 DNA topoisomerase 132 560 4.9E-127 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Gene3D G3DSA:2.70.20.10 188 470 8.2E-167 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 SMART SM00437 253 523 2.8E-115 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 677 714 5.8E-14 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 589 623 7.7E-14 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 634 670 1.4E-14 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Gene3D G3DSA:3.30.65.10 626 675 2.8E-8 T 12-10-2018 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Gene3D G3DSA:3.30.65.10 575 625 3.3E-9 T 12-10-2018 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 290 312 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 AFE_0015 d7c084fdf0acf119c9de23c579e8b962 851 Gene3D G3DSA:1.10.460.10 139 563 8.2E-167 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFE_0675 3c4054bac7565ef530e9dd2d5d8eecbd 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 AFE_0675 3c4054bac7565ef530e9dd2d5d8eecbd 107 SUPERFAMILY SSF89360 1 96 7.06E-32 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFE_0675 3c4054bac7565ef530e9dd2d5d8eecbd 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 106 5.2E-35 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 AFE_0675 3c4054bac7565ef530e9dd2d5d8eecbd 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 2.5E-22 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFE_0675 3c4054bac7565ef530e9dd2d5d8eecbd 107 Gene3D G3DSA:2.60.300.12 2 107 7.0E-36 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFE_0675 3c4054bac7565ef530e9dd2d5d8eecbd 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 106 5.1E-51 T 12-10-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 AFE_3040 45a8b08d4bd930a2620a6e2257e1f504 215 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 4 214 54.423 T 12-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 AFE_3040 45a8b08d4bd930a2620a6e2257e1f504 215 Pfam PF01634 ATP phosphoribosyltransferase 54 210 2.0E-51 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFE_3040 45a8b08d4bd930a2620a6e2257e1f504 215 Gene3D G3DSA:3.40.190.10 6 204 1.0E-72 T 12-10-2018 AFE_3040 45a8b08d4bd930a2620a6e2257e1f504 215 SUPERFAMILY SSF53850 3 212 9.99E-66 T 12-10-2018 AFE_3040 45a8b08d4bd930a2620a6e2257e1f504 215 Gene3D G3DSA:3.40.190.10 96 182 1.0E-72 T 12-10-2018 AFE_3040 45a8b08d4bd930a2620a6e2257e1f504 215 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 190 1.5E-59 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFE_3040 45a8b08d4bd930a2620a6e2257e1f504 215 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 149 170 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 AFE_0726 694efe3e8ba243f9f310b932e56d96bf 258 Pfam PF13444 Acetyltransferase (GNAT) domain 38 138 1.8E-32 T 12-10-2018 AFE_0726 694efe3e8ba243f9f310b932e56d96bf 258 Gene3D G3DSA:3.40.630.30 23 185 7.6E-24 T 12-10-2018 AFE_0726 694efe3e8ba243f9f310b932e56d96bf 258 SUPERFAMILY SSF55729 22 226 4.21E-39 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_0775 e5928dfdf86c71cc510b947073175474 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 146 687 3.8E-152 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFE_0775 e5928dfdf86c71cc510b947073175474 752 Gene3D G3DSA:3.30.365.10 5 748 1.6E-196 T 12-10-2018 AFE_0775 e5928dfdf86c71cc510b947073175474 752 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 28 125 2.8E-9 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFE_0775 e5928dfdf86c71cc510b947073175474 752 SUPERFAMILY SSF54665 16 124 6.54E-16 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily AFE_0775 e5928dfdf86c71cc510b947073175474 752 SUPERFAMILY SSF56003 137 745 7.46E-163 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 AFE_0775 e5928dfdf86c71cc510b947073175474 752 SMART SM01008 27 130 9.8E-4 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFE_0863 e2618e768afa2ee7782382119f42d369 477 Pfam PF02321 Outer membrane efflux protein 67 255 8.8E-13 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_0863 e2618e768afa2ee7782382119f42d369 477 Pfam PF02321 Outer membrane efflux protein 288 467 1.2E-18 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_0863 e2618e768afa2ee7782382119f42d369 477 Gene3D G3DSA:2.20.200.10 103 354 2.3E-93 T 12-10-2018 AFE_0863 e2618e768afa2ee7782382119f42d369 477 Gene3D G3DSA:1.20.1600.10 58 469 2.3E-93 T 12-10-2018 AFE_0863 e2618e768afa2ee7782382119f42d369 477 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 469 1.3E-95 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 AFE_0863 e2618e768afa2ee7782382119f42d369 477 SUPERFAMILY SSF56954 1 470 1.83E-75 T 12-10-2018 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 SMART SM00487 599 789 1.1E-32 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 SUPERFAMILY SSF141259 472 547 1.44E-15 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Gene3D G3DSA:3.30.2060.10 129 214 1.2E-98 T 12-10-2018 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 SUPERFAMILY SSF52540 523 782 1.6E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Gene3D G3DSA:3.40.50.11140 351 450 1.5E-10 T 12-10-2018 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Pfam PF00271 Helicase conserved C-terminal domain 802 908 1.2E-13 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Pfam PF00270 DEAD/DEAH box helicase 604 761 7.9E-19 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Pfam PF03461 TRCF domain 1009 1102 5.1E-25 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Gene3D G3DSA:3.40.50.11180 24 329 1.2E-98 T 12-10-2018 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Gene3D G3DSA:3.90.1150.50 1005 1148 7.8E-38 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 SMART SM01058 477 575 2.4E-35 T 12-10-2018 IPR003711 CarD-like/TRCF domain AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 SUPERFAMILY SSF143517 996 1145 4.45E-39 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Gene3D G3DSA:3.40.50.300 541 780 5.8E-226 T 12-10-2018 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 146 1081 0.0 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Gene3D G3DSA:3.40.50.300 477 988 5.8E-226 T 12-10-2018 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Gene3D G3DSA:2.30.30.840 481 540 5.8E-226 T 12-10-2018 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Pfam PF02559 CarD-like/TRCF domain 478 574 1.9E-23 T 12-10-2018 IPR003711 CarD-like/TRCF domain AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 SMART SM00490 825 909 1.6E-14 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 SUPERFAMILY SSF52540 17 338 3.85E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 SUPERFAMILY SSF52540 781 989 1.33E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 SUPERFAMILY SSF52540 348 460 9.56E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 SMART SM00982 1008 1108 9.4E-40 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 AFE_0369 a9ab935be9513a08b752a21c1f1a14f0 1149 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 31 1109 27.065 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 AFE_0144 b9ddd5d3585229bb787cefcfd633cd35 291 Gene3D G3DSA:3.30.950.10 122 241 3.0E-38 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFE_0144 b9ddd5d3585229bb787cefcfd633cd35 291 PIRSF PIRSF005917 3 286 3.5E-86 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 AFE_0144 b9ddd5d3585229bb787cefcfd633cd35 291 SUPERFAMILY SSF53790 13 233 3.53E-71 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFE_0144 b9ddd5d3585229bb787cefcfd633cd35 291 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 92 103 - T 12-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 AFE_0144 b9ddd5d3585229bb787cefcfd633cd35 291 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 214 1.7E-28 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFE_0144 b9ddd5d3585229bb787cefcfd633cd35 291 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 14 235 33.067 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 AFE_0144 b9ddd5d3585229bb787cefcfd633cd35 291 Gene3D G3DSA:3.40.1010.10 2 121 1.0E-34 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFE_0144 b9ddd5d3585229bb787cefcfd633cd35 291 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 15 282 1.6E-66 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 AFE_2738 652e5d2b7949807235b35b1c09c0d189 127 Pfam PF04379 ApaG domain 19 104 1.9E-36 T 12-10-2018 IPR007474 ApaG domain AFE_2738 652e5d2b7949807235b35b1c09c0d189 127 SUPERFAMILY SSF110069 7 127 7.98E-48 T 12-10-2018 IPR036767 ApaG domain superfamily AFE_2738 652e5d2b7949807235b35b1c09c0d189 127 Gene3D G3DSA:2.60.40.1470 2 127 1.0E-50 T 12-10-2018 IPR036767 ApaG domain superfamily AFE_2738 652e5d2b7949807235b35b1c09c0d189 127 Hamap MF_00791 Protein ApaG [apaG]. 2 127 32.506 T 12-10-2018 IPR023065 Uncharacterised protein family ApaG AFE_0701 35eac69ccb7a6b6834702a2c2610698f 320 Gene3D G3DSA:4.10.480.10 195 271 1.9E-20 T 12-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily AFE_0701 35eac69ccb7a6b6834702a2c2610698f 320 SUPERFAMILY SSF56770 2 268 1.44E-76 T 12-10-2018 AFE_0701 35eac69ccb7a6b6834702a2c2610698f 320 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 221 247 3.8E-10 T 12-10-2018 AFE_0701 35eac69ccb7a6b6834702a2c2610698f 320 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 97 111 3.8E-10 T 12-10-2018 AFE_0701 35eac69ccb7a6b6834702a2c2610698f 320 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 248 261 3.8E-10 T 12-10-2018 AFE_0701 35eac69ccb7a6b6834702a2c2610698f 320 Gene3D G3DSA:3.40.50.700 1 194 5.3E-55 T 12-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily AFE_0701 35eac69ccb7a6b6834702a2c2610698f 320 PIRSF PIRSF000310 1 319 6.5E-92 T 12-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 AFE_0701 35eac69ccb7a6b6834702a2c2610698f 320 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 196 268 6.5E-23 T 12-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal AFE_0701 35eac69ccb7a6b6834702a2c2610698f 320 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 12 175 7.6E-32 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_0100 ad4ec312ffba93cbc2f42bc0b8b3ef0c 361 Gene3D G3DSA:2.40.50.100 59 270 3.0E-21 T 12-10-2018 AFE_0100 ad4ec312ffba93cbc2f42bc0b8b3ef0c 361 Pfam PF13533 Biotin-lipoyl like 59 109 3.3E-10 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain AFE_0100 ad4ec312ffba93cbc2f42bc0b8b3ef0c 361 SUPERFAMILY SSF111369 59 150 3.27E-10 T 12-10-2018 AFE_0100 ad4ec312ffba93cbc2f42bc0b8b3ef0c 361 Gene3D G3DSA:2.40.30.170 271 332 3.0E-21 T 12-10-2018 AFE_0100 ad4ec312ffba93cbc2f42bc0b8b3ef0c 361 Gene3D G3DSA:1.10.287.470 93 224 3.0E-21 T 12-10-2018 AFE_2788 3bd661cd0526dee71e0baaf8b990d9bb 117 Gene3D G3DSA:3.30.110.70 10 116 1.6E-26 T 12-10-2018 AFE_2788 3bd661cd0526dee71e0baaf8b990d9bb 117 Pfam PF01906 Putative heavy-metal-binding 8 114 3.0E-31 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 AFE_2788 3bd661cd0526dee71e0baaf8b990d9bb 117 SUPERFAMILY SSF117782 9 115 7.85E-30 T 12-10-2018 IPR035439 UPF0145 domain superfamily AFE_2788 3bd661cd0526dee71e0baaf8b990d9bb 117 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 8 114 21.411 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 AFE_1212 ffc0979cbe099ad30a0a15273b745c90 385 SUPERFAMILY SSF53756 127 363 1.38E-21 T 12-10-2018 AFE_1212 ffc0979cbe099ad30a0a15273b745c90 385 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 299 330 1.8E-4 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 AFE_1212 ffc0979cbe099ad30a0a15273b745c90 385 Gene3D G3DSA:3.40.50.2000 254 363 1.1E-7 T 12-10-2018 AFE_1212 ffc0979cbe099ad30a0a15273b745c90 385 SUPERFAMILY SSF48452 38 113 2.71E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 PRINTS PR00811 Bacterial general secretion pathway protein D signature 605 629 2.6E-19 T 12-10-2018 IPR001775 GspD/PilQ family AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 PRINTS PR00811 Bacterial general secretion pathway protein D signature 730 748 2.6E-19 T 12-10-2018 IPR001775 GspD/PilQ family AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 PRINTS PR00811 Bacterial general secretion pathway protein D signature 499 509 2.6E-19 T 12-10-2018 IPR001775 GspD/PilQ family AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 PRINTS PR00811 Bacterial general secretion pathway protein D signature 753 767 2.6E-19 T 12-10-2018 IPR001775 GspD/PilQ family AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 Gene3D G3DSA:3.30.1370.120 398 497 1.6E-13 T 12-10-2018 IPR038591 NolW-like superfamily AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 SMART SM00965 326 374 8.6E-7 T 12-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 Pfam PF03958 Bacterial type II/III secretion system short domain 399 499 2.0E-16 T 12-10-2018 IPR005644 NolW-like AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 Gene3D G3DSA:3.55.50.30 288 397 1.2E-31 T 12-10-2018 AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 Pfam PF00263 Bacterial type II and III secretion system protein 609 765 8.0E-52 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 301 765 1.2E-163 T 12-10-2018 IPR013355 Type IV pilus secretin PilQ AFE_0735 1b24ad2e3848bd1ca7c6d15e7a873759 784 Gene3D G3DSA:2.60.40.3470 160 287 1.4E-22 T 12-10-2018 AFE_2189 d710ac74ad77cf13a2e51fa9b8831583 337 Pfam PF00005 ABC transporter 17 142 8.6E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2189 d710ac74ad77cf13a2e51fa9b8831583 337 Gene3D G3DSA:2.40.50.100 259 328 5.2E-6 T 12-10-2018 AFE_2189 d710ac74ad77cf13a2e51fa9b8831583 337 SUPERFAMILY SSF50331 216 332 8.05E-13 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFE_2189 d710ac74ad77cf13a2e51fa9b8831583 337 Gene3D G3DSA:3.40.50.300 4 212 1.4E-54 T 12-10-2018 AFE_2189 d710ac74ad77cf13a2e51fa9b8831583 337 ProSitePatterns PS00211 ABC transporters family signature. 114 128 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2189 d710ac74ad77cf13a2e51fa9b8831583 337 SMART SM00382 19 198 9.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2189 d710ac74ad77cf13a2e51fa9b8831583 337 Gene3D G3DSA:2.40.50.140 217 332 5.2E-6 T 12-10-2018 AFE_2189 d710ac74ad77cf13a2e51fa9b8831583 337 SUPERFAMILY SSF52540 13 221 3.48E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2319 a1c89f3f284a87b740b80bbd93371f22 226 Gene3D G3DSA:1.10.10.10 125 226 2.4E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2319 a1c89f3f284a87b740b80bbd93371f22 226 Pfam PF00072 Response regulator receiver domain 4 112 1.9E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_2319 a1c89f3f284a87b740b80bbd93371f22 226 SMART SM00448 2 112 4.1E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_2319 a1c89f3f284a87b740b80bbd93371f22 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 1.9E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2319 a1c89f3f284a87b740b80bbd93371f22 226 Gene3D G3DSA:3.40.50.2300 2 124 4.3E-33 T 12-10-2018 AFE_2319 a1c89f3f284a87b740b80bbd93371f22 226 SMART SM00862 146 222 8.0E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2319 a1c89f3f284a87b740b80bbd93371f22 226 SUPERFAMILY SSF46894 123 223 2.83E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFE_2319 a1c89f3f284a87b740b80bbd93371f22 226 SUPERFAMILY SSF52172 2 120 1.42E-37 T 12-10-2018 IPR011006 CheY-like superfamily AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 Pfam PF00702 haloacid dehalogenase-like hydrolase 359 573 9.1E-43 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 Pfam PF00122 E1-E2 ATPase 163 341 1.0E-49 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 Gene3D G3DSA:3.40.50.1000 356 609 8.3E-94 T 12-10-2018 IPR023214 HAD superfamily AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00943 Copper-transporting ATPase signature 632 646 6.8E-7 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00943 Copper-transporting ATPase signature 345 360 6.8E-7 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00943 Copper-transporting ATPase signature 285 299 6.8E-7 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00943 Copper-transporting ATPase signature 86 105 6.8E-7 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00943 Copper-transporting ATPase signature 536 553 6.8E-7 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 484 495 9.1E-30 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 362 376 9.1E-30 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 559 578 9.1E-30 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 506 516 9.1E-30 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 212 226 9.1E-30 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 582 594 9.1E-30 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 Gene3D G3DSA:3.40.1110.10 373 491 8.3E-94 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 SUPERFAMILY SSF81653 165 262 1.44E-25 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 83 667 8.1E-186 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 138 639 5.6E-88 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 SUPERFAMILY SSF81665 101 645 2.75E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 364 370 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 Gene3D G3DSA:2.70.150.20 150 266 1.5E-37 T 12-10-2018 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 101 666 1.9E-181 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFE_2779 0b092426f7b225e90fde5153f0d701b4 674 SUPERFAMILY SSF56784 361 664 1.76E-56 T 12-10-2018 IPR036412 HAD-like superfamily AFE_0407 c9a250a7c813da71f41180788e8405d6 408 PIRSF PIRSF000726 53 408 2.5E-143 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFE_0407 c9a250a7c813da71f41180788e8405d6 408 PIRSF PIRSF000726 1 60 1.2E-22 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFE_0407 c9a250a7c813da71f41180788e8405d6 408 Gene3D G3DSA:3.40.1160.10 1 252 9.8E-91 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_0407 c9a250a7c813da71f41180788e8405d6 408 Pfam PF13840 ACT domain 338 397 2.7E-16 T 12-10-2018 IPR027795 CASTOR, ACT domain AFE_0407 c9a250a7c813da71f41180788e8405d6 408 SUPERFAMILY SSF55021 330 403 2.09E-24 T 12-10-2018 AFE_0407 c9a250a7c813da71f41180788e8405d6 408 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 62 401 7.5E-122 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFE_0407 c9a250a7c813da71f41180788e8405d6 408 Gene3D G3DSA:3.30.70.260 253 402 1.3E-56 T 12-10-2018 AFE_0407 c9a250a7c813da71f41180788e8405d6 408 Pfam PF01842 ACT domain 266 321 3.2E-10 T 12-10-2018 IPR002912 ACT domain AFE_0407 c9a250a7c813da71f41180788e8405d6 408 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 3.8E-137 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFE_0407 c9a250a7c813da71f41180788e8405d6 408 SUPERFAMILY SSF53633 4 243 4.32E-75 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_0407 c9a250a7c813da71f41180788e8405d6 408 Gene3D G3DSA:3.30.70.260 260 337 1.3E-56 T 12-10-2018 AFE_0407 c9a250a7c813da71f41180788e8405d6 408 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFE_0407 c9a250a7c813da71f41180788e8405d6 408 SUPERFAMILY SSF55021 248 325 3.77E-18 T 12-10-2018 AFE_0407 c9a250a7c813da71f41180788e8405d6 408 Pfam PF00696 Amino acid kinase family 3 229 3.0E-52 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 Pfam PF00072 Response regulator receiver domain 6 115 6.4E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 SUPERFAMILY SSF46689 351 442 4.66E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 Gene3D G3DSA:3.40.50.2300 1 130 7.0E-37 T 12-10-2018 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 Gene3D G3DSA:1.10.10.60 376 445 8.1E-13 T 12-10-2018 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 162 175 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 Gene3D G3DSA:1.10.8.60 309 375 5.3E-23 T 12-10-2018 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 351 360 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 SUPERFAMILY SSF52172 1 181 5.12E-42 T 12-10-2018 IPR011006 CheY-like superfamily AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 SMART SM00382 158 301 1.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 423 443 1.1E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 406 423 1.1E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 SUPERFAMILY SSF52540 137 381 1.41E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 Gene3D G3DSA:3.40.50.300 131 308 4.8E-60 T 12-10-2018 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 SMART SM00448 4 115 5.4E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 Pfam PF02954 Bacterial regulatory protein, Fis family 402 438 6.2E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0027 3651641b5cd338ffd4f72d6046f2f541 455 Pfam PF00158 Sigma-54 interaction domain 138 304 3.5E-66 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_2340 22d95be72049569c5225fb99328ecd83 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 14 44 4.0E-9 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2340 22d95be72049569c5225fb99328ecd83 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 5.1E-17 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2340 22d95be72049569c5225fb99328ecd83 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 5.1E-17 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2340 22d95be72049569c5225fb99328ecd83 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 5.1E-17 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2340 22d95be72049569c5225fb99328ecd83 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 5.1E-17 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2340 22d95be72049569c5225fb99328ecd83 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 22.67 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2340 22d95be72049569c5225fb99328ecd83 71 Pfam PF01165 Ribosomal protein S21 3 55 1.5E-23 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2340 22d95be72049569c5225fb99328ecd83 71 Gene3D G3DSA:1.20.5.1150 16 54 1.4E-20 T 12-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2340 22d95be72049569c5225fb99328ecd83 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.0E-25 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2340 22d95be72049569c5225fb99328ecd83 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 12-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2850 192ca20066f07f6eef9fee063e680953 302 Pfam PF00589 Phage integrase family 117 288 6.4E-45 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_2850 192ca20066f07f6eef9fee063e680953 302 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 11 302 52.361 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD AFE_2850 192ca20066f07f6eef9fee063e680953 302 SUPERFAMILY SSF56349 114 300 2.65E-52 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_2850 192ca20066f07f6eef9fee063e680953 302 Gene3D G3DSA:1.10.150.130 9 104 1.7E-16 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFE_2850 192ca20066f07f6eef9fee063e680953 302 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 9 302 55.677 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 AFE_2850 192ca20066f07f6eef9fee063e680953 302 SUPERFAMILY SSF47823 10 104 6.08E-25 T 12-10-2018 AFE_2850 192ca20066f07f6eef9fee063e680953 302 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 13 95 4.4E-13 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFE_2850 192ca20066f07f6eef9fee063e680953 302 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 15 301 3.8E-106 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 AFE_2850 192ca20066f07f6eef9fee063e680953 302 Gene3D G3DSA:1.10.443.10 116 296 1.2E-62 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 SUPERFAMILY SSF141734 11 113 4.18E-46 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 11 114 30.536 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 Gene3D G3DSA:3.10.20.400 6 101 1.4E-38 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 60 110 1.0E-17 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 13 218 34.909 T 12-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 127 213 19.854 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 130 213 6.3E-30 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 SUPERFAMILY SSF101386 129 219 9.16E-23 T 12-10-2018 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 133 216 1.4E-13 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 Gene3D G3DSA:1.10.287.1080 127 219 5.4E-30 T 12-10-2018 AFE_3047 b3ff15f68bd1cc7801b9997907b044b3 230 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 37 110 4.7E-33 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFE_2911 161ace769b207f5d973f70e150233fa5 438 Gene3D G3DSA:1.10.3430.10 22 438 2.2E-142 T 12-10-2018 IPR029020 Ammonium/urea transporter AFE_2911 161ace769b207f5d973f70e150233fa5 438 SUPERFAMILY SSF111352 35 418 2.09E-131 T 12-10-2018 AFE_2911 161ace769b207f5d973f70e150233fa5 438 Pfam PF00909 Ammonium Transporter Family 41 437 2.2E-122 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AFE_2911 161ace769b207f5d973f70e150233fa5 438 ProSitePatterns PS01219 Ammonium transporters signature. 194 219 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AFE_2911 161ace769b207f5d973f70e150233fa5 438 TIGRFAM TIGR00836 amt: ammonium transporter 39 437 5.0E-138 T 12-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 SUPERFAMILY SSF52540 376 805 5.74E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 Gene3D G3DSA:3.40.50.300 375 806 4.8E-155 T 12-10-2018 AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 9 1124 18.681 T 12-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 10 806 1.2E-245 T 12-10-2018 AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 Gene3D G3DSA:1.10.486.10 452 661 4.8E-155 T 12-10-2018 AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 SUPERFAMILY SSF52980 821 1118 1.61E-40 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 Gene3D G3DSA:3.40.50.10930 12 326 7.4E-105 T 12-10-2018 AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 PIRSF PIRSF000980 9 1086 5.6E-287 T 12-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 SUPERFAMILY SSF52540 9 366 2.06E-92 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 10 1060 2.5E-280 T 12-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 AFE_2931 c3d04983937c5dbb17eea08a9bc764eb 1130 Gene3D G3DSA:1.10.10.160 86 209 7.4E-105 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 Pfam PF00512 His Kinase A (phospho-acceptor) domain 684 749 4.7E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 Gene3D G3DSA:1.20.120.620 414 516 2.8E-6 T 12-10-2018 IPR038318 KdpD, transmembrane domain superfamily AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 Gene3D G3DSA:3.30.565.10 757 906 1.4E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 SMART SM00388 682 749 1.1E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 Gene3D G3DSA:3.30.450.40 525 672 3.6E-26 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 Pfam PF13493 Domain of unknown function (DUF4118) 425 520 1.3E-7 T 12-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 SUPERFAMILY SSF47384 677 750 3.34E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 SUPERFAMILY SSF52402 259 382 4.5E-7 T 12-10-2018 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 Gene3D G3DSA:3.40.50.300 26 236 1.3E-91 T 12-10-2018 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 SUPERFAMILY SSF55874 739 905 5.63E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 28 237 1.7E-91 T 12-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 SMART SM00387 793 904 7.0E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 Gene3D G3DSA:1.10.287.130 673 751 5.1E-15 T 12-10-2018 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 PRINTS PR00344 Bacterial sensor protein C-terminal signature 830 844 1.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 PRINTS PR00344 Bacterial sensor protein C-terminal signature 848 858 1.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 PRINTS PR00344 Bacterial sensor protein C-terminal signature 863 881 1.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 PRINTS PR00344 Bacterial sensor protein C-terminal signature 888 901 1.5E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 795 903 3.7E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2229 90991ee0fd766114d42c5cd48546f9da 913 SUPERFAMILY SSF55781 522 665 1.29E-8 T 12-10-2018 AFE_2362 bd48a9c2f373cad8934e1f8dc2e8a8f0 144 PIRSF PIRSF000077 38 142 4.9E-33 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFE_2362 bd48a9c2f373cad8934e1f8dc2e8a8f0 144 ProSitePatterns PS00194 Thioredoxin family active site. 60 78 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFE_2362 bd48a9c2f373cad8934e1f8dc2e8a8f0 144 TIGRFAM TIGR01068 thioredoxin: thioredoxin 44 140 1.7E-33 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFE_2362 bd48a9c2f373cad8934e1f8dc2e8a8f0 144 Pfam PF00085 Thioredoxin 42 140 3.5E-30 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFE_2362 bd48a9c2f373cad8934e1f8dc2e8a8f0 144 SUPERFAMILY SSF52833 27 141 1.29E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_2362 bd48a9c2f373cad8934e1f8dc2e8a8f0 144 Gene3D G3DSA:2.20.28.140 1 34 1.2E-14 T 12-10-2018 AFE_2362 bd48a9c2f373cad8934e1f8dc2e8a8f0 144 Gene3D G3DSA:3.40.30.10 35 141 5.3E-33 T 12-10-2018 AFE_2362 bd48a9c2f373cad8934e1f8dc2e8a8f0 144 PRINTS PR00421 Thioredoxin family signature 67 76 4.5E-9 T 12-10-2018 AFE_2362 bd48a9c2f373cad8934e1f8dc2e8a8f0 144 PRINTS PR00421 Thioredoxin family signature 59 67 4.5E-9 T 12-10-2018 AFE_2362 bd48a9c2f373cad8934e1f8dc2e8a8f0 144 PRINTS PR00421 Thioredoxin family signature 107 118 4.5E-9 T 12-10-2018 AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 Gene3D G3DSA:3.40.50.300 364 547 1.3E-64 T 12-10-2018 AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 SUPERFAMILY SSF52540 367 541 5.15E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 8 359 1.8E-100 T 12-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 365 526 2.6E-61 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 Gene3D G3DSA:3.40.50.620 146 361 1.2E-70 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 Pfam PF14306 PUA-like domain 8 132 6.9E-39 T 12-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 Pfam PF01747 ATP-sulfurylase 151 360 1.3E-68 T 12-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 367 542 33.542 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 SUPERFAMILY SSF88697 7 134 1.09E-36 T 12-10-2018 IPR015947 PUA-like superfamily AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 Pfam PF01583 Adenylylsulphate kinase 368 524 5.1E-62 T 12-10-2018 AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 SUPERFAMILY SSF52374 162 362 2.53E-56 T 12-10-2018 AFE_0539 4ef909b2b02c8029f2f53366684d96e7 557 Gene3D G3DSA:3.10.400.10 2 133 1.8E-41 T 12-10-2018 AFE_0756 71cb4206718594f7eb8a136ab4cdd3e6 230 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 4 207 1.9E-41 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like AFE_0756 71cb4206718594f7eb8a136ab4cdd3e6 230 Gene3D G3DSA:3.40.50.1000 4 219 4.3E-74 T 12-10-2018 IPR023214 HAD superfamily AFE_0756 71cb4206718594f7eb8a136ab4cdd3e6 230 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 193 2.8E-37 T 12-10-2018 AFE_0756 71cb4206718594f7eb8a136ab4cdd3e6 230 SUPERFAMILY SSF56784 3 216 2.21E-34 T 12-10-2018 IPR036412 HAD-like superfamily AFE_0756 71cb4206718594f7eb8a136ab4cdd3e6 230 Gene3D G3DSA:1.20.1440.100 15 88 4.3E-74 T 12-10-2018 AFE_0756 71cb4206718594f7eb8a136ab4cdd3e6 230 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 193 1.2E-24 T 12-10-2018 AFE_2175 b26c4220b91ccdb79c368b14063f47ff 251 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 117 131 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFE_2175 b26c4220b91ccdb79c368b14063f47ff 251 SUPERFAMILY SSF55120 79 245 2.33E-37 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2175 b26c4220b91ccdb79c368b14063f47ff 251 Gene3D G3DSA:3.30.70.1560 146 228 1.7E-47 T 12-10-2018 AFE_2175 b26c4220b91ccdb79c368b14063f47ff 251 Gene3D G3DSA:3.10.290.10 18 79 2.8E-13 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFE_2175 b26c4220b91ccdb79c368b14063f47ff 251 Pfam PF01479 S4 domain 21 62 1.1E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_2175 b26c4220b91ccdb79c368b14063f47ff 251 Gene3D G3DSA:3.30.70.580 80 244 1.7E-47 T 12-10-2018 AFE_2175 b26c4220b91ccdb79c368b14063f47ff 251 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 83 241 1.6E-38 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFE_2175 b26c4220b91ccdb79c368b14063f47ff 251 Pfam PF00849 RNA pseudouridylate synthase 79 211 5.7E-15 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2175 b26c4220b91ccdb79c368b14063f47ff 251 SUPERFAMILY SSF55174 20 108 2.8E-12 T 12-10-2018 AFE_2175 b26c4220b91ccdb79c368b14063f47ff 251 SMART SM00363 20 76 6.3E-4 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_2321 412f58e38dbd65110c14aefa02efb7f1 362 SUPERFAMILY SSF51679 10 356 3.4E-76 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFE_2321 412f58e38dbd65110c14aefa02efb7f1 362 Gene3D G3DSA:3.20.20.30 5 358 7.7E-91 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AFE_2321 412f58e38dbd65110c14aefa02efb7f1 362 Pfam PF00296 Luciferase-like monooxygenase 17 324 1.6E-52 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 SUPERFAMILY SSF47384 209 275 4.51E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 Pfam PF00512 His Kinase A (phospho-acceptor) domain 220 275 6.4E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 SMART SM00388 218 279 4.4E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 Gene3D G3DSA:3.30.450.300 24 141 5.5E-6 T 12-10-2018 IPR038421 Sensor histidine kinase RisS, periplasmic domain superfamily AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 Gene3D G3DSA:3.30.565.10 280 423 1.7E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 SMART SM00387 316 423 3.8E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 415 4.5E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 SUPERFAMILY SSF55874 279 421 1.96E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 Gene3D G3DSA:1.10.287.130 207 275 1.6E-14 T 12-10-2018 AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 2.4E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 2.4E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2318 7a60675d824013c5c6af7ce9ae756cd3 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 2.4E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0995 3a0e5251b7b1ae2ced0c481dceacbb7c 349 Pfam PF00589 Phage integrase family 156 311 3.5E-33 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_0995 3a0e5251b7b1ae2ced0c481dceacbb7c 349 Gene3D G3DSA:1.10.150.130 55 153 1.8E-8 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFE_0995 3a0e5251b7b1ae2ced0c481dceacbb7c 349 Gene3D G3DSA:1.10.443.10 154 324 1.1E-35 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_0995 3a0e5251b7b1ae2ced0c481dceacbb7c 349 SUPERFAMILY SSF56349 57 319 2.18E-54 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_0501 82de14dea85d2279b065949559a9166c 117 Gene3D G3DSA:3.10.450.50 1 117 2.0E-37 T 12-10-2018 AFE_0501 82de14dea85d2279b065949559a9166c 117 SUPERFAMILY SSF54427 9 116 2.48E-16 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFE_0501 82de14dea85d2279b065949559a9166c 117 Pfam PF12680 SnoaL-like domain 12 111 4.1E-9 T 12-10-2018 IPR037401 SnoaL-like domain AFE_0925 6aef013fa0aa72de47068e6b830c0b7b 269 Pfam PF00557 Metallopeptidase family M24 20 255 5.0E-52 T 12-10-2018 IPR000994 Peptidase M24 AFE_0925 6aef013fa0aa72de47068e6b830c0b7b 269 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 181 199 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFE_0925 6aef013fa0aa72de47068e6b830c0b7b 269 SUPERFAMILY SSF55920 12 267 1.13E-89 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like AFE_0925 6aef013fa0aa72de47068e6b830c0b7b 269 Gene3D G3DSA:3.90.230.10 11 267 5.2E-108 T 12-10-2018 AFE_0925 6aef013fa0aa72de47068e6b830c0b7b 269 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 13 263 2.4E-94 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFE_0925 6aef013fa0aa72de47068e6b830c0b7b 269 Hamap MF_01974 Methionine aminopeptidase [map]. 11 264 41.13 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFE_0925 6aef013fa0aa72de47068e6b830c0b7b 269 PRINTS PR00599 Methionine aminopeptidase-1 signature 105 121 5.8E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFE_0925 6aef013fa0aa72de47068e6b830c0b7b 269 PRINTS PR00599 Methionine aminopeptidase-1 signature 175 187 5.8E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFE_0925 6aef013fa0aa72de47068e6b830c0b7b 269 PRINTS PR00599 Methionine aminopeptidase-1 signature 83 96 5.8E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFE_0925 6aef013fa0aa72de47068e6b830c0b7b 269 PRINTS PR00599 Methionine aminopeptidase-1 signature 206 218 5.8E-21 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFE_1434 3f9b0dc307a63d9f7d5fd132593ecc2e 243 Gene3D G3DSA:1.10.10.10 132 232 8.4E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1434 3f9b0dc307a63d9f7d5fd132593ecc2e 243 SUPERFAMILY SSF46894 132 229 4.33E-30 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFE_1434 3f9b0dc307a63d9f7d5fd132593ecc2e 243 SMART SM00448 8 121 2.4E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_1434 3f9b0dc307a63d9f7d5fd132593ecc2e 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 229 1.8E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_1434 3f9b0dc307a63d9f7d5fd132593ecc2e 243 Gene3D G3DSA:3.40.50.2300 2 130 2.3E-35 T 12-10-2018 AFE_1434 3f9b0dc307a63d9f7d5fd132593ecc2e 243 Pfam PF00072 Response regulator receiver domain 10 122 3.2E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_1434 3f9b0dc307a63d9f7d5fd132593ecc2e 243 SUPERFAMILY SSF52172 8 129 8.97E-40 T 12-10-2018 IPR011006 CheY-like superfamily AFE_1434 3f9b0dc307a63d9f7d5fd132593ecc2e 243 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 7 230 1.3E-91 T 12-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 AFE_1434 3f9b0dc307a63d9f7d5fd132593ecc2e 243 SMART SM00862 155 230 1.0E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_0007 6782794691986e0790017d0231876f28 814 Pfam PF00577 Outer membrane usher protein 505 715 1.1E-19 T 12-10-2018 IPR000015 Outer membrane usher protein GO:0009297|GO:0015473|GO:0016020 AFE_0007 6782794691986e0790017d0231876f28 814 Pfam PF00577 Outer membrane usher protein 232 412 2.8E-13 T 12-10-2018 IPR000015 Outer membrane usher protein GO:0009297|GO:0015473|GO:0016020 AFE_0007 6782794691986e0790017d0231876f28 814 Gene3D G3DSA:2.60.40.3110 240 329 7.6E-13 T 12-10-2018 AFE_0007 6782794691986e0790017d0231876f28 814 Pfam PF13953 PapC C-terminal domain 733 794 9.5E-11 T 12-10-2018 IPR025949 PapC-like, C-terminal domain AFE_0007 6782794691986e0790017d0231876f28 814 Gene3D G3DSA:2.60.40.2610 637 728 4.9E-14 T 12-10-2018 AFE_2949 61565bb378db16f92e6b5d9d2389a625 118 SUPERFAMILY SSF81301 5 112 6.38E-39 T 12-10-2018 AFE_2949 61565bb378db16f92e6b5d9d2389a625 118 Pfam PF02410 Ribosomal silencing factor during starvation 12 105 3.5E-28 T 12-10-2018 AFE_2949 61565bb378db16f92e6b5d9d2389a625 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 106 25.542 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS AFE_2949 61565bb378db16f92e6b5d9d2389a625 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 9 105 2.9E-37 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS AFE_2949 61565bb378db16f92e6b5d9d2389a625 118 Gene3D G3DSA:3.30.460.10 3 117 2.1E-38 T 12-10-2018 AFE_3194 1606bd2b8c1e914073dd32e064e58cc5 403 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 315 401 8.3E-23 T 12-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain AFE_3194 1606bd2b8c1e914073dd32e064e58cc5 403 Pfam PF04326 Putative DNA-binding domain 16 129 7.2E-15 T 12-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 AFE_3194 1606bd2b8c1e914073dd32e064e58cc5 403 Gene3D G3DSA:3.30.950.30 3 137 1.5E-18 T 12-10-2018 IPR038461 Schlafen, AAA domain superfamily AFE_3194 1606bd2b8c1e914073dd32e064e58cc5 403 Gene3D G3DSA:3.30.565.60 251 402 2.9E-40 T 12-10-2018 IPR038475 RecG, C-terminal domain superfamily AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 Gene3D G3DSA:3.40.50.1000 457 576 7.3E-24 T 12-10-2018 IPR023214 HAD superfamily AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 20 686 7.8E-297 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 318 324 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 SUPERFAMILY SSF81653 117 211 7.06E-21 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 382 611 8.7E-44 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 76 337 4.7E-30 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 Gene3D G3DSA:3.40.1110.10 327 456 2.9E-43 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 13 689 38.286 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 Pfam PF00122 E1-E2 ATPase 117 294 9.1E-33 T 12-10-2018 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 Gene3D G3DSA:2.70.150.20 109 216 3.9E-25 T 12-10-2018 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 SUPERFAMILY SSF56784 304 569 1.57E-34 T 12-10-2018 IPR036412 HAD-like superfamily AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 473 483 1.3E-24 T 12-10-2018 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 526 545 1.3E-24 T 12-10-2018 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 158 172 1.3E-24 T 12-10-2018 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 561 1.3E-24 T 12-10-2018 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 316 330 1.3E-24 T 12-10-2018 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 Pfam PF00702 haloacid dehalogenase-like hydrolase 312 540 5.7E-33 T 12-10-2018 AFE_2474 5883124b38f1a9a087cd2e3888a24234 689 SUPERFAMILY SSF81665 33 310 6.28E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFE_0392 fe8eef0b5c5cc80dc1face7a8a6ebd37 128 SUPERFAMILY SSF89919 8 119 8.9E-24 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily AFE_0392 fe8eef0b5c5cc80dc1face7a8a6ebd37 128 Gene3D G3DSA:3.30.300.20 10 107 3.4E-21 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFE_0392 fe8eef0b5c5cc80dc1face7a8a6ebd37 128 ProSitePatterns PS01319 Ribosome-binding factor A signature. 83 104 - T 12-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 AFE_0392 fe8eef0b5c5cc80dc1face7a8a6ebd37 128 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 10 117 23.58 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFE_0392 fe8eef0b5c5cc80dc1face7a8a6ebd37 128 Pfam PF02033 Ribosome-binding factor A 11 117 8.7E-20 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFE_2531 27e21801cafb95c2900aae23d2b39b3d 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 4.1E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2531 27e21801cafb95c2900aae23d2b39b3d 308 Gene3D G3DSA:1.10.10.10 1 90 1.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2531 27e21801cafb95c2900aae23d2b39b3d 308 SUPERFAMILY SSF53850 86 299 5.04E-50 T 12-10-2018 AFE_2531 27e21801cafb95c2900aae23d2b39b3d 308 Pfam PF03466 LysR substrate binding domain 87 295 5.6E-48 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_2531 27e21801cafb95c2900aae23d2b39b3d 308 Gene3D G3DSA:3.40.190.290 91 301 4.8E-47 T 12-10-2018 AFE_2531 27e21801cafb95c2900aae23d2b39b3d 308 SUPERFAMILY SSF46785 4 111 1.88E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2531 27e21801cafb95c2900aae23d2b39b3d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2531 27e21801cafb95c2900aae23d2b39b3d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2531 27e21801cafb95c2900aae23d2b39b3d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 PRINTS PR01050 Pyruvate kinase family signature 60 76 9.1E-55 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 PRINTS PR01050 Pyruvate kinase family signature 185 199 9.1E-55 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 PRINTS PR01050 Pyruvate kinase family signature 215 241 9.1E-55 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 PRINTS PR01050 Pyruvate kinase family signature 292 310 9.1E-55 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 PRINTS PR01050 Pyruvate kinase family signature 311 327 9.1E-55 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 PRINTS PR01050 Pyruvate kinase family signature 242 266 9.1E-55 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 PRINTS PR01050 Pyruvate kinase family signature 267 291 9.1E-55 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 470 1.3E-26 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 SUPERFAMILY SSF51621 2 336 2.2E-91 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 Pfam PF00224 Pyruvate kinase, barrel domain 2 336 7.2E-116 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 Gene3D G3DSA:2.40.33.10 71 167 7.3E-158 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 472 5.2E-151 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 SUPERFAMILY SSF50800 71 162 6.63E-24 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 Gene3D G3DSA:3.20.20.60 3 333 7.3E-158 T 12-10-2018 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 SUPERFAMILY SSF52935 321 473 1.44E-36 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_3249 15d961c487d1e63b29dff5e99bb9d89e 479 Gene3D G3DSA:3.40.1380.20 334 468 7.3E-158 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_0717 d6fef5cf8d43ced2c792e775dc642be0 109 Gene3D G3DSA:2.20.28.10 66 98 2.0E-26 T 12-10-2018 AFE_0717 d6fef5cf8d43ced2c792e775dc642be0 109 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 108 1.7E-29 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFE_0717 d6fef5cf8d43ced2c792e775dc642be0 109 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 109 20.724 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFE_0717 d6fef5cf8d43ced2c792e775dc642be0 109 PIRSF PIRSF004761 1 109 7.6E-29 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFE_0717 d6fef5cf8d43ced2c792e775dc642be0 109 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 31 73 - T 12-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site AFE_0717 d6fef5cf8d43ced2c792e775dc642be0 109 Gene3D G3DSA:3.30.2320.50 2 105 2.0E-26 T 12-10-2018 AFE_1986 9d3c73df2ca27b9a6e65dc0ea2ac770a 170 PIRSF PIRSF001467 1 166 6.2E-28 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 AFE_1986 9d3c73df2ca27b9a6e65dc0ea2ac770a 170 SUPERFAMILY SSF50891 2 162 2.63E-58 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFE_1986 9d3c73df2ca27b9a6e65dc0ea2ac770a 170 Gene3D G3DSA:2.40.100.10 2 165 4.0E-66 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily AFE_1986 9d3c73df2ca27b9a6e65dc0ea2ac770a 170 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 1.1E-12 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFE_1986 9d3c73df2ca27b9a6e65dc0ea2ac770a 170 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 1.1E-12 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFE_1986 9d3c73df2ca27b9a6e65dc0ea2ac770a 170 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 122 137 1.1E-12 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFE_1986 9d3c73df2ca27b9a6e65dc0ea2ac770a 170 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 161 1.1E-47 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFE_1986 9d3c73df2ca27b9a6e65dc0ea2ac770a 170 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 12-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 AFE_0381 a376944f8d4d794f36f1fef6e13dd4f3 77 SUPERFAMILY SSF101744 3 72 6.8E-16 T 12-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 AFE_0381 a376944f8d4d794f36f1fef6e13dd4f3 77 Gene3D G3DSA:2.30.30.400 8 76 1.0E-11 T 12-10-2018 IPR038626 Rof-like superfamily AFE_0381 a376944f8d4d794f36f1fef6e13dd4f3 77 Pfam PF07073 Modulator of Rho-dependent transcription termination (ROF) 7 73 1.0E-9 T 12-10-2018 IPR009778 Modulator of Rho-dependent transcription termination AFE_0420 c1f7064f602d9f7c9c4e2a623416350e 257 Gene3D G3DSA:1.10.8.400 204 257 2.0E-20 T 12-10-2018 AFE_0420 c1f7064f602d9f7c9c4e2a623416350e 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0420 c1f7064f602d9f7c9c4e2a623416350e 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0420 c1f7064f602d9f7c9c4e2a623416350e 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0420 c1f7064f602d9f7c9c4e2a623416350e 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0420 c1f7064f602d9f7c9c4e2a623416350e 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.4E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0420 c1f7064f602d9f7c9c4e2a623416350e 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 1.4E-84 T 12-10-2018 AFE_0420 c1f7064f602d9f7c9c4e2a623416350e 257 PIRSF PIRSF000094 1 257 9.2E-108 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFE_0420 c1f7064f602d9f7c9c4e2a623416350e 257 SUPERFAMILY SSF51735 6 254 1.18E-64 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0420 c1f7064f602d9f7c9c4e2a623416350e 257 Gene3D G3DSA:3.40.50.720 7 203 3.8E-34 T 12-10-2018 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 SUPERFAMILY SSF50621 253 412 9.42E-52 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 29 367 2.7E-26 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 410 41.211 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 409 1.4E-150 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 297 315 5.2E-31 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 74 91 5.2E-31 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 377 399 5.2E-31 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 163 172 5.2E-31 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 269 288 1.0E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 56 74 1.0E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 76 88 1.0E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 367 380 1.0E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 189 202 1.0E-22 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 Gene3D G3DSA:3.20.20.10 34 274 6.4E-148 T 12-10-2018 IPR029066 PLP-binding barrel AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 Gene3D G3DSA:2.40.37.10 17 406 6.4E-148 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 SUPERFAMILY SSF51419 26 281 3.34E-78 T 12-10-2018 IPR029066 PLP-binding barrel AFE_3279 45cdb45f490c0a9077d63db5ff9a8e81 419 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 36 278 8.7E-63 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFE_1914 ba2a6b399836033b2e7935d7b5a31ea9 333 Gene3D G3DSA:3.40.50.300 14 165 2.8E-38 T 12-10-2018 AFE_1914 ba2a6b399836033b2e7935d7b5a31ea9 333 SUPERFAMILY SSF52540 21 204 1.13E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1914 ba2a6b399836033b2e7935d7b5a31ea9 333 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 208 319 4.2E-6 T 12-10-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_1914 ba2a6b399836033b2e7935d7b5a31ea9 333 Pfam PF13177 DNA polymerase III, delta subunit 22 165 5.3E-34 T 12-10-2018 AFE_1543 bcebd72d4f1e25e8a68265cc02a77fca 275 Pfam PF13289 SIR2-like domain 102 257 3.2E-24 T 12-10-2018 IPR039444 SIR2-like domain AFE_0905 29d234c471c4c887c62549eaeddc22da 101 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 93 2.4E-37 T 12-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 AFE_0905 29d234c471c4c887c62549eaeddc22da 101 Gene3D G3DSA:4.10.520.10 1 92 5.1E-33 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_0905 29d234c471c4c887c62549eaeddc22da 101 SMART SM00411 1 91 2.4E-39 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_0905 29d234c471c4c887c62549eaeddc22da 101 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 3.1E-17 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_0905 29d234c471c4c887c62549eaeddc22da 101 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 3.1E-17 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_0905 29d234c471c4c887c62549eaeddc22da 101 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 3.1E-17 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_0905 29d234c471c4c887c62549eaeddc22da 101 SUPERFAMILY SSF47729 1 91 3.24E-30 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_0905 29d234c471c4c887c62549eaeddc22da 101 Pfam PF00216 Bacterial DNA-binding protein 1 90 4.8E-30 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_2066 c9fb74313ad63bccb68bf02ea07d3dc4 429 Gene3D G3DSA:3.90.190.20 287 424 9.7E-25 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_2066 c9fb74313ad63bccb68bf02ea07d3dc4 429 SUPERFAMILY SSF53623 21 271 7.06E-72 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_2066 c9fb74313ad63bccb68bf02ea07d3dc4 429 PIRSF PIRSF001563 11 423 2.7E-94 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AFE_2066 c9fb74313ad63bccb68bf02ea07d3dc4 429 Pfam PF08245 Mur ligase middle domain 49 189 1.5E-6 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFE_2066 c9fb74313ad63bccb68bf02ea07d3dc4 429 Gene3D G3DSA:3.40.1190.10 9 282 3.5E-71 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_2066 c9fb74313ad63bccb68bf02ea07d3dc4 429 SUPERFAMILY SSF53244 287 418 1.45E-24 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_2066 c9fb74313ad63bccb68bf02ea07d3dc4 429 Pfam PF02875 Mur ligase family, glutamate ligase domain 286 342 2.0E-5 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFE_2066 c9fb74313ad63bccb68bf02ea07d3dc4 429 TIGRFAM TIGR01499 folC: bifunctional protein FolC 26 419 3.9E-90 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 PRINTS PR00094 Adenylate kinase signature 6 19 2.7E-30 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 PRINTS PR00094 Adenylate kinase signature 83 99 2.7E-30 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 PRINTS PR00094 Adenylate kinase signature 34 48 2.7E-30 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 PRINTS PR00094 Adenylate kinase signature 179 193 2.7E-30 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 PRINTS PR00094 Adenylate kinase signature 162 177 2.7E-30 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 Pfam PF05191 Adenylate kinase, active site lid 129 164 1.4E-16 T 12-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 TIGRFAM TIGR01351 adk: adenylate kinase 5 214 2.3E-72 T 12-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 ProSitePatterns PS00113 Adenylate kinase signature. 83 94 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 Hamap MF_00235 Adenylate kinase [adk]. 3 215 45.217 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 SUPERFAMILY SSF52540 4 215 3.06E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 Pfam PF00406 Adenylate kinase 8 191 1.8E-47 T 12-10-2018 AFE_0348 da1f1ac931de0c36c94cad9e168fffcc 218 Gene3D G3DSA:3.40.50.300 2 217 2.6E-72 T 12-10-2018 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR01159 DNA gyrase subunit B signature 469 478 3.8E-73 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR01159 DNA gyrase subunit B signature 753 765 3.8E-73 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR01159 DNA gyrase subunit B signature 769 785 3.8E-73 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR01159 DNA gyrase subunit B signature 5 15 3.8E-73 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR01159 DNA gyrase subunit B signature 373 393 3.8E-73 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR01159 DNA gyrase subunit B signature 311 327 3.8E-73 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR01159 DNA gyrase subunit B signature 195 208 3.8E-73 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR01159 DNA gyrase subunit B signature 180 195 3.8E-73 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR01159 DNA gyrase subunit B signature 359 373 3.8E-73 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR01159 DNA gyrase subunit B signature 219 241 3.8E-73 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 Pfam PF00204 DNA gyrase B 220 389 2.3E-57 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 Gene3D G3DSA:3.30.230.10 220 391 4.6E-71 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 728 789 3.6E-30 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 Gene3D G3DSA:3.40.50.670 701 799 2.3E-25 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 SUPERFAMILY SSF55874 5 217 5.37E-72 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 SMART SM00433 35 793 1.2E-268 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR00418 DNA topoisomerase II family signature 486 502 6.6E-72 T 12-10-2018 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR00418 DNA topoisomerase II family signature 267 280 6.6E-72 T 12-10-2018 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR00418 DNA topoisomerase II family signature 70 83 6.6E-72 T 12-10-2018 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR00418 DNA topoisomerase II family signature 419 433 6.6E-72 T 12-10-2018 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR00418 DNA topoisomerase II family signature 524 536 6.6E-72 T 12-10-2018 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR00418 DNA topoisomerase II family signature 504 521 6.6E-72 T 12-10-2018 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR00418 DNA topoisomerase II family signature 35 50 6.6E-72 T 12-10-2018 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR00418 DNA topoisomerase II family signature 113 127 6.6E-72 T 12-10-2018 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 PRINTS PR00418 DNA topoisomerase II family signature 732 748 6.6E-72 T 12-10-2018 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 SUPERFAMILY SSF54211 220 390 1.01E-57 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 Gene3D G3DSA:3.40.50.670 397 572 1.4E-74 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 SMART SM00387 31 175 5.9E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 SUPERFAMILY SSF56719 393 791 3.14E-86 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 172 2.0E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 Gene3D G3DSA:3.30.565.10 2 219 1.8E-90 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 800 100.303 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 ProSitePatterns PS00177 DNA topoisomerase II signature. 421 429 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 Pfam PF01751 Toprim domain 418 530 4.5E-17 T 12-10-2018 IPR006171 TOPRIM domain AFE_0003 aee87478ceca9cad30f3783a02ae1174 800 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 800 1.8E-302 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_0449 443dcd697b73c757235da59cc939511e 494 Pfam PF00512 His Kinase A (phospho-acceptor) domain 266 331 3.3E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0449 443dcd697b73c757235da59cc939511e 494 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 379 487 6.1E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0449 443dcd697b73c757235da59cc939511e 494 SMART SM00388 265 333 7.3E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0449 443dcd697b73c757235da59cc939511e 494 SUPERFAMILY SSF47384 248 332 2.55E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_0449 443dcd697b73c757235da59cc939511e 494 Pfam PF00672 HAMP domain 214 261 3.8E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFE_0449 443dcd697b73c757235da59cc939511e 494 SMART SM00387 378 489 8.4E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0449 443dcd697b73c757235da59cc939511e 494 Gene3D G3DSA:3.30.565.10 339 492 6.5E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0449 443dcd697b73c757235da59cc939511e 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 429 8.9E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0449 443dcd697b73c757235da59cc939511e 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 443 8.9E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0449 443dcd697b73c757235da59cc939511e 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 467 8.9E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0449 443dcd697b73c757235da59cc939511e 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 486 8.9E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0449 443dcd697b73c757235da59cc939511e 494 SMART SM00304 213 264 3.2E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFE_0449 443dcd697b73c757235da59cc939511e 494 SUPERFAMILY SSF55874 323 487 1.05E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0449 443dcd697b73c757235da59cc939511e 494 Gene3D G3DSA:1.10.287.130 211 328 1.7E-21 T 12-10-2018 AFE_2292 6ccd25d8a5fb776b8d9e39dffef357a3 773 Pfam PF00593 TonB dependent receptor 310 772 5.1E-29 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_2292 6ccd25d8a5fb776b8d9e39dffef357a3 773 Gene3D G3DSA:2.40.170.20 202 773 6.1E-46 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily AFE_2292 6ccd25d8a5fb776b8d9e39dffef357a3 773 Pfam PF07715 TonB-dependent Receptor Plug Domain 84 175 1.7E-8 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain AFE_2292 6ccd25d8a5fb776b8d9e39dffef357a3 773 SUPERFAMILY SSF56935 68 773 4.03E-67 T 12-10-2018 AFE_2292 6ccd25d8a5fb776b8d9e39dffef357a3 773 Gene3D G3DSA:2.170.130.10 67 195 5.7E-11 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_2559 e274ef82430631b41715616805750d5f 342 SUPERFAMILY SSF102114 16 319 8.76E-70 T 12-10-2018 AFE_2559 e274ef82430631b41715616805750d5f 342 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 30 41 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2559 e274ef82430631b41715616805750d5f 342 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 15 342 35.738 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2559 e274ef82430631b41715616805750d5f 342 Pfam PF13353 4Fe-4S single cluster domain 31 128 5.4E-8 T 12-10-2018 AFE_2559 e274ef82430631b41715616805750d5f 342 Pfam PF06463 Molybdenum Cofactor Synthesis C 194 324 5.9E-32 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2559 e274ef82430631b41715616805750d5f 342 Pfam PF04055 Radical SAM superfamily 28 188 2.2E-29 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_2559 e274ef82430631b41715616805750d5f 342 SMART SM00729 24 228 4.4E-8 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFE_2559 e274ef82430631b41715616805750d5f 342 Gene3D G3DSA:3.20.20.70 12 342 1.0E-89 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2559 e274ef82430631b41715616805750d5f 342 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 15 342 8.8E-113 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Pfam PF02754 Cysteine-rich domain 1017 1105 5.7E-5 T 12-10-2018 IPR004017 Cysteine-rich domain AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Pfam PF02754 Cysteine-rich domain 1142 1230 0.005 T 12-10-2018 IPR004017 Cysteine-rich domain AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 SUPERFAMILY SSF55103 416 547 8.18E-15 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Pfam PF11880 Domain of unknown function (DUF3400) 1233 1277 6.0E-22 T 12-10-2018 IPR021817 Protein of unknown function DUF3400 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 SUPERFAMILY SSF56176 128 394 2.2E-52 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 SUPERFAMILY SSF55103 672 775 3.11E-27 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Pfam PF01565 FAD binding domain 165 310 1.0E-27 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Gene3D G3DSA:3.30.70.2740 664 737 3.4E-6 T 12-10-2018 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Pfam PF12447 Protein of unknown function (DUF3683) 4 115 3.8E-48 T 12-10-2018 IPR022153 Protein of unknown function DUF3683 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Gene3D G3DSA:3.30.465.40 126 322 2.8E-37 T 12-10-2018 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 SUPERFAMILY SSF46548 807 904 3.4E-12 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 874 885 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Pfam PF13183 4Fe-4S dicluster domain 809 888 3.3E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Gene3D G3DSA:1.10.1060.10 789 906 1.1E-5 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Pfam PF02913 FAD linked oxidases, C-terminal domain 395 543 6.2E-9 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFE_1769 589bc320ab979837f4cda39aee1ef06f 1277 Pfam PF02913 FAD linked oxidases, C-terminal domain 673 773 2.0E-20 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 SUPERFAMILY SSF111369 132 333 1.31E-18 T 12-10-2018 AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 Gene3D G3DSA:2.40.420.20 333 425 2.9E-19 T 12-10-2018 AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 Gene3D G3DSA:1.10.287.470 194 206 6.9E-28 T 12-10-2018 AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 Gene3D G3DSA:2.40.420.20 109 119 4.1E-12 T 12-10-2018 AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 117 329 8.6E-78 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 Gene3D G3DSA:2.40.50.100 207 256 6.9E-28 T 12-10-2018 AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 Gene3D G3DSA:2.40.30.170 120 133 4.1E-12 T 12-10-2018 AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 Gene3D G3DSA:2.40.50.100 134 168 4.1E-12 T 12-10-2018 AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 Gene3D G3DSA:1.10.287.470 169 183 4.1E-12 T 12-10-2018 AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 222 399 6.4E-36 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_1948 2431757c7c7b1e50c395d7de3c854378 439 Gene3D G3DSA:2.40.30.170 257 330 6.9E-28 T 12-10-2018 AFE_0661 3cdb81c1f3b1b2902acc772272ec73c0 351 Pfam PF01594 AI-2E family transporter 18 341 7.0E-42 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 Gene3D G3DSA:3.80.30.20 145 375 1.1E-83 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 4.4E-140 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 Pfam PF00919 Uncharacterized protein family UPF0004 4 103 1.5E-26 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 Pfam PF04055 Radical SAM superfamily 151 325 8.1E-32 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 Pfam PF01938 TRAM domain 379 439 7.3E-11 T 12-10-2018 IPR002792 TRAM domain AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 438 1.2E-159 T 12-10-2018 AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 2 440 72.7 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 SMART SM00729 147 367 5.4E-61 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 Gene3D G3DSA:3.40.50.12160 3 137 6.6E-31 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily AFE_0596 3467c0df875f556c77e9819b7e37ad42 451 SUPERFAMILY SSF102114 125 371 2.49E-60 T 12-10-2018 AFE_2651 cb6d7b730548635dec795103927bdc38 364 Pfam PF05425 Copper resistance protein D 192 318 2.8E-15 T 12-10-2018 IPR008457 Copper resistance protein D GO:0016021 AFE_0845 eb90f608a398628c59e20375c5790a9a 675 Pfam PF02151 UvrB/uvrC motif 628 660 4.7E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 AFE_0845 eb90f608a398628c59e20375c5790a9a 675 Gene3D G3DSA:3.40.50.300 1 161 6.7E-66 T 12-10-2018 AFE_0845 eb90f608a398628c59e20375c5790a9a 675 Pfam PF04851 Type III restriction enzyme, res subunit 16 87 2.7E-6 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFE_0845 eb90f608a398628c59e20375c5790a9a 675 Gene3D G3DSA:3.40.50.300 274 413 1.7E-52 T 12-10-2018 AFE_0845 eb90f608a398628c59e20375c5790a9a 675 SUPERFAMILY SSF52540 4 414 5.78E-133 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0845 eb90f608a398628c59e20375c5790a9a 675 SUPERFAMILY SSF46600 623 663 9.29E-11 T 12-10-2018 IPR036876 UVR domain superfamily AFE_0845 eb90f608a398628c59e20375c5790a9a 675 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 659 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 AFE_0845 eb90f608a398628c59e20375c5790a9a 675 Pfam PF00271 Helicase conserved C-terminal domain 441 543 2.1E-17 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0845 eb90f608a398628c59e20375c5790a9a 675 Gene3D G3DSA:3.30.2060.10 162 245 1.2E-18 T 12-10-2018 AFE_0845 eb90f608a398628c59e20375c5790a9a 675 SUPERFAMILY SSF52540 37 577 1.2E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0845 eb90f608a398628c59e20375c5790a9a 675 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 662 42.892 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 AFE_0845 eb90f608a398628c59e20375c5790a9a 675 SMART SM00487 9 425 1.2E-24 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_0845 eb90f608a398628c59e20375c5790a9a 675 Gene3D G3DSA:3.40.50.300 414 595 3.5E-48 T 12-10-2018 AFE_0845 eb90f608a398628c59e20375c5790a9a 675 Pfam PF12344 Ultra-violet resistance protein B 551 592 9.3E-21 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain AFE_0845 eb90f608a398628c59e20375c5790a9a 675 Gene3D G3DSA:4.10.860.10 608 666 2.6E-15 T 12-10-2018 AFE_0845 eb90f608a398628c59e20375c5790a9a 675 SMART SM00490 459 545 7.3E-20 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0747 02d651b7f06d4fcf5c6d8789d38e3d3c 338 Gene3D G3DSA:3.40.50.720 1 181 1.6E-78 T 12-10-2018 AFE_0747 02d651b7f06d4fcf5c6d8789d38e3d3c 338 SUPERFAMILY SSF48179 183 331 1.31E-70 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFE_0747 02d651b7f06d4fcf5c6d8789d38e3d3c 338 PIRSF PIRSF000116 2 209 3.1E-47 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFE_0747 02d651b7f06d4fcf5c6d8789d38e3d3c 338 PIRSF PIRSF000116 202 332 7.5E-14 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFE_0747 02d651b7f06d4fcf5c6d8789d38e3d3c 338 SUPERFAMILY SSF51735 1 182 2.01E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0747 02d651b7f06d4fcf5c6d8789d38e3d3c 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 4.4E-139 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFE_0747 02d651b7f06d4fcf5c6d8789d38e3d3c 338 Gene3D G3DSA:1.10.3730.40 182 338 2.0E-75 T 12-10-2018 AFE_0747 02d651b7f06d4fcf5c6d8789d38e3d3c 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 1.0E-75 T 12-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFE_0747 02d651b7f06d4fcf5c6d8789d38e3d3c 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 6.5E-68 T 12-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFE_0747 02d651b7f06d4fcf5c6d8789d38e3d3c 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 45.857 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 1.4E-51 T 12-10-2018 AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 5.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 Gene3D G3DSA:3.40.50.720 1 245 2.2E-70 T 12-10-2018 AFE_0129 e50b2da4138fd0e8c87891eae14063ed 246 SUPERFAMILY SSF51735 5 245 1.63E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 421 1.1E-128 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 PRINTS PR00148 Enolase signature 333 347 6.0E-43 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 PRINTS PR00148 Enolase signature 160 173 6.0E-43 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 PRINTS PR00148 Enolase signature 362 379 6.0E-43 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 PRINTS PR00148 Enolase signature 37 51 6.0E-43 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 PRINTS PR00148 Enolase signature 310 321 6.0E-43 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 PRINTS PR00148 Enolase signature 106 122 6.0E-43 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 SMART SM01193 4 133 6.7E-90 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 Pfam PF03952 Enolase, N-terminal domain 4 133 1.1E-57 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 ProSitePatterns PS00164 Enolase signature. 333 346 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 424 3.3E-203 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 Gene3D G3DSA:3.30.390.10 1 126 1.9E-53 T 12-10-2018 IPR029017 Enolase-like, N-terminal AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 Gene3D G3DSA:3.20.20.120 128 426 2.2E-132 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 SUPERFAMILY SSF54826 4 136 1.68E-52 T 12-10-2018 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 Hamap MF_00318 Enolase [eno]. 2 410 43.951 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 PIRSF PIRSF001400 1 424 3.2E-186 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 SMART SM01192 138 424 6.8E-219 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0849 8bb58f0cac9bf2706f5aa26201216f5c 426 SUPERFAMILY SSF51604 139 425 7.07E-126 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFE_0389 c11c295f40b155908cb8f0a9f479fd9b 150 SUPERFAMILY SSF74942 83 150 9.68E-15 T 12-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily AFE_0389 c11c295f40b155908cb8f0a9f479fd9b 150 SUPERFAMILY SSF75420 3 82 7.45E-20 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily AFE_0389 c11c295f40b155908cb8f0a9f479fd9b 150 Pfam PF02576 RimP N-terminal domain 16 82 1.6E-22 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal AFE_0389 c11c295f40b155908cb8f0a9f479fd9b 150 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 3 150 21.756 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 AFE_0389 c11c295f40b155908cb8f0a9f479fd9b 150 Pfam PF17384 RimP C-terminal SH3 domain 85 150 4.0E-12 T 12-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal AFE_0389 c11c295f40b155908cb8f0a9f479fd9b 150 Gene3D G3DSA:3.30.300.70 1 79 7.8E-18 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SUPERFAMILY SSF48452 93 381 3.04E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SUPERFAMILY SSF48452 419 593 4.43E-30 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 Pfam PF14559 Tetratricopeptide repeat 537 599 4.0E-8 T 12-10-2018 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 Pfam PF14559 Tetratricopeptide repeat 163 225 4.7E-9 T 12-10-2018 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SMART SM00028 219 252 0.88 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SMART SM00028 84 117 190.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SMART SM00028 559 592 0.09 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SMART SM00028 321 354 87.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SMART SM00028 287 320 69.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SMART SM00028 355 390 200.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SMART SM00028 151 184 280.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SMART SM00028 525 558 18.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SMART SM00028 456 489 0.18 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 SMART SM00028 490 524 33.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 Gene3D G3DSA:1.25.40.10 71 382 1.1E-44 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 Gene3D G3DSA:1.25.40.10 383 603 9.8E-40 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 Pfam PF13432 Tetratricopeptide repeat 460 525 1.4E-6 T 12-10-2018 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 Pfam PF13432 Tetratricopeptide repeat 293 355 6.3E-6 T 12-10-2018 AFE_2762 ecbd62e96301e1027b09bd43ef0dfc27 603 Pfam PF13432 Tetratricopeptide repeat 97 150 0.0084 T 12-10-2018 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 423 531 3.4E-28 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 SUPERFAMILY SSF51905 83 413 1.21E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 119 129 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 Gene3D G3DSA:3.30.390.30 422 547 8.3E-45 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 SUPERFAMILY SSF55424 422 545 3.44E-32 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 SUPERFAMILY SSF55008 7 75 2.23E-16 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 PIRSF PIRSF000350 4 547 4.6E-262 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 TIGRFAM TIGR02053 MerA: mercury(II) reductase 86 547 6.9E-185 T 12-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 PRINTS PR00945 Mercuric reductase class II signature 18 28 9.9E-89 T 12-10-2018 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 PRINTS PR00945 Mercuric reductase class II signature 223 240 9.9E-89 T 12-10-2018 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 PRINTS PR00945 Mercuric reductase class II signature 96 114 9.9E-89 T 12-10-2018 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 PRINTS PR00945 Mercuric reductase class II signature 131 150 9.9E-89 T 12-10-2018 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 PRINTS PR00945 Mercuric reductase class II signature 520 539 9.9E-89 T 12-10-2018 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 PRINTS PR00945 Mercuric reductase class II signature 278 293 9.9E-89 T 12-10-2018 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 PRINTS PR00945 Mercuric reductase class II signature 455 475 9.9E-89 T 12-10-2018 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 PRINTS PR00945 Mercuric reductase class II signature 258 275 9.9E-89 T 12-10-2018 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 86 404 2.2E-63 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 Gene3D G3DSA:3.50.50.60 88 405 2.8E-117 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 Gene3D G3DSA:3.30.70.100 7 70 4.5E-16 T 12-10-2018 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 Gene3D G3DSA:3.50.50.60 231 347 2.8E-117 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2481 8d02a2541abd00a6ed2a0284b12111aa 547 Pfam PF00403 Heavy-metal-associated domain 9 67 2.3E-11 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFE_0176 4957e837a6523309ac3828d5adcf78b3 285 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 258 35.572 T 12-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 AFE_0176 4957e837a6523309ac3828d5adcf78b3 285 SUPERFAMILY SSF53335 8 264 2.3E-76 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0176 4957e837a6523309ac3828d5adcf78b3 285 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 233 239 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFE_0176 4957e837a6523309ac3828d5adcf78b3 285 Gene3D G3DSA:3.40.50.150 1 269 1.1E-85 T 12-10-2018 AFE_0176 4957e837a6523309ac3828d5adcf78b3 285 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 32 261 1.3E-62 T 12-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 AFE_0293 eb6937bf017cc9bb2ee5f969dcb08c2d 383 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 22 373 8.4E-144 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 AFE_0293 eb6937bf017cc9bb2ee5f969dcb08c2d 383 PIRSF PIRSF000443 2 382 3.0E-140 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 AFE_0293 eb6937bf017cc9bb2ee5f969dcb08c2d 383 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 10 375 30.356 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 AFE_0293 eb6937bf017cc9bb2ee5f969dcb08c2d 383 Gene3D G3DSA:1.10.1740.110 187 293 1.8E-143 T 12-10-2018 AFE_0293 eb6937bf017cc9bb2ee5f969dcb08c2d 383 Gene3D G3DSA:3.40.50.1820 26 363 1.8E-143 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_0293 eb6937bf017cc9bb2ee5f969dcb08c2d 383 SUPERFAMILY SSF53474 14 376 2.99E-105 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_0293 eb6937bf017cc9bb2ee5f969dcb08c2d 383 Pfam PF00561 alpha/beta hydrolase fold 51 360 2.5E-33 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFE_2111 ac3dab4c2bc2583f3b9b22c4c2647b47 490 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 92.065 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFE_2111 ac3dab4c2bc2583f3b9b22c4c2647b47 490 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 1.2E-177 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFE_2111 ac3dab4c2bc2583f3b9b22c4c2647b47 490 SUPERFAMILY SSF75304 2 483 8.76E-170 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFE_2111 ac3dab4c2bc2583f3b9b22c4c2647b47 490 ProSitePatterns PS00571 Amidases signature. 151 182 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFE_2111 ac3dab4c2bc2583f3b9b22c4c2647b47 490 Pfam PF01425 Amidase 24 466 5.4E-165 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFE_2111 ac3dab4c2bc2583f3b9b22c4c2647b47 490 Gene3D G3DSA:3.90.1300.10 2 486 6.3E-208 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFE_2910 fd4d74125b9406d0a4a3d090f521bbbb 644 SUPERFAMILY SSF52540 75 349 9.52E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2910 fd4d74125b9406d0a4a3d090f521bbbb 644 Pfam PF06798 PrkA serine protein kinase C-terminal domain 383 636 2.6E-68 T 12-10-2018 IPR010650 PrkA C-terminal domain AFE_2910 fd4d74125b9406d0a4a3d090f521bbbb 644 Pfam PF08298 PrkA AAA domain 20 379 6.1E-163 T 12-10-2018 IPR013153 PrkA AAA domain AFE_2910 fd4d74125b9406d0a4a3d090f521bbbb 644 SMART SM00763 19 380 1.3E-194 T 12-10-2018 IPR013153 PrkA AAA domain AFE_2910 fd4d74125b9406d0a4a3d090f521bbbb 644 PIRSF PIRSF000549 1 644 2.8E-269 T 12-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 AFE_1733 55208b6b7a8a3821cce5faf6fcb8ae8c 147 Gene3D G3DSA:3.30.160.250 3 76 1.1E-11 T 12-10-2018 AFE_1733 55208b6b7a8a3821cce5faf6fcb8ae8c 147 SUPERFAMILY SSF143100 1 64 2.88E-11 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like AFE_1812 9ca45edeae96b53606b993c35d2f6a10 330 Gene3D G3DSA:3.40.50.970 3 189 6.4E-73 T 12-10-2018 AFE_1812 9ca45edeae96b53606b993c35d2f6a10 330 SUPERFAMILY SSF52922 191 323 9.95E-36 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_1812 9ca45edeae96b53606b993c35d2f6a10 330 Gene3D G3DSA:3.40.50.920 190 325 6.2E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_1812 9ca45edeae96b53606b993c35d2f6a10 330 Pfam PF02780 Transketolase, C-terminal domain 194 315 2.2E-36 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFE_1812 9ca45edeae96b53606b993c35d2f6a10 330 Pfam PF02779 Transketolase, pyrimidine binding domain 5 177 1.1E-40 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_1812 9ca45edeae96b53606b993c35d2f6a10 330 SMART SM00861 4 179 1.5E-53 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_1812 9ca45edeae96b53606b993c35d2f6a10 330 SUPERFAMILY SSF52518 2 203 1.07E-60 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_2415 3c2f9bf119e0defdc5ba466d0b5f3d27 80 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 8 59 4.9E-14 T 12-10-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system AFE_1498 4625ddc7288785e6bcdc5d9da0fcd42e 307 SUPERFAMILY SSF53850 29 305 2.5E-42 T 12-10-2018 AFE_1498 4625ddc7288785e6bcdc5d9da0fcd42e 307 Pfam PF13531 Bacterial extracellular solute-binding protein 30 298 2.7E-48 T 12-10-2018 AFE_1498 4625ddc7288785e6bcdc5d9da0fcd42e 307 Gene3D G3DSA:3.40.190.10 30 293 2.4E-48 T 12-10-2018 AFE_1498 4625ddc7288785e6bcdc5d9da0fcd42e 307 Gene3D G3DSA:3.40.190.10 110 264 2.4E-48 T 12-10-2018 AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 Gene3D G3DSA:1.10.1140.10 351 469 3.3E-60 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 SUPERFAMILY SSF47917 351 467 3.92E-54 T 12-10-2018 AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 11 466 1.5E-248 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 14 79 1.3E-17 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 Hamap MF_01347 ATP synthase subunit beta [atpB]. 9 466 56.14 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 136 348 1.8E-64 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 SUPERFAMILY SSF52540 83 353 5.8E-91 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 SUPERFAMILY SSF50615 7 81 8.37E-22 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 Gene3D G3DSA:3.40.50.300 82 350 1.3E-111 T 12-10-2018 AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 SMART SM00382 148 411 1.6E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_3203 6c13a9de2f347a7c9f54a8c6a60f45ed 469 Gene3D G3DSA:2.40.10.170 9 81 7.0E-25 T 12-10-2018 AFE_3044 c6c73e98e2e013daa834e30bc0add33f 223 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 7 213 35.47 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFE_3044 c6c73e98e2e013daa834e30bc0add33f 223 SUPERFAMILY SSF52317 7 213 8.31E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_3044 c6c73e98e2e013daa834e30bc0add33f 223 Gene3D G3DSA:3.40.50.880 3 220 2.1E-70 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_3044 c6c73e98e2e013daa834e30bc0add33f 223 Pfam PF00117 Glutamine amidotransferase class-I 10 200 1.5E-17 T 12-10-2018 IPR017926 Glutamine amidotransferase AFE_3044 c6c73e98e2e013daa834e30bc0add33f 223 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 8 212 1.3E-62 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFE_3044 c6c73e98e2e013daa834e30bc0add33f 223 PIRSF PIRSF000495 6 215 1.4E-67 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFE_1145 15b2753d271c036ecf64719c8a9b9cd8 301 Gene3D G3DSA:1.10.443.10 130 301 1.9E-43 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_1145 15b2753d271c036ecf64719c8a9b9cd8 301 Gene3D G3DSA:1.10.150.130 2 114 3.8E-7 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFE_1145 15b2753d271c036ecf64719c8a9b9cd8 301 SUPERFAMILY SSF56349 126 299 8.83E-41 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_1145 15b2753d271c036ecf64719c8a9b9cd8 301 Pfam PF00589 Phage integrase family 132 299 2.0E-31 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_0013 f1beb41c73d402c53eee0632755e5849 227 Gene3D G3DSA:2.160.20.70 120 227 1.2E-27 T 12-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 AFE_0013 f1beb41c73d402c53eee0632755e5849 227 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 124 222 9.9E-29 T 12-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 AFE_0013 f1beb41c73d402c53eee0632755e5849 227 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 1 226 22.262 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 AFE_0013 f1beb41c73d402c53eee0632755e5849 227 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 3 97 1.2E-10 T 12-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 AFE_0013 f1beb41c73d402c53eee0632755e5849 227 SUPERFAMILY SSF63848 122 225 3.4E-28 T 12-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 AFE_0013 f1beb41c73d402c53eee0632755e5849 227 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 5 225 3.2E-55 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 AFE_0013 f1beb41c73d402c53eee0632755e5849 227 Gene3D G3DSA:3.30.750.120 1 111 3.1E-16 T 12-10-2018 IPR038061 MinC, Proteobacteria, N-terminal domain superfamily AFE_0223 4feb955d2271af78acbcc1925115d27e 304 SUPERFAMILY SSF54211 133 275 3.41E-51 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0223 4feb955d2271af78acbcc1925115d27e 304 SUPERFAMILY SSF54211 3 125 2.43E-42 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0223 4feb955d2271af78acbcc1925115d27e 304 Gene3D G3DSA:3.30.230.20 1 127 1.9E-48 T 12-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 AFE_0223 4feb955d2271af78acbcc1925115d27e 304 Gene3D G3DSA:3.30.1700.10 128 302 2.7E-68 T 12-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 AFE_0223 4feb955d2271af78acbcc1925115d27e 304 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 279 46.291 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 AFE_0223 4feb955d2271af78acbcc1925115d27e 304 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 2.8E-108 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 AFE_0223 4feb955d2271af78acbcc1925115d27e 304 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 289 5.2E-113 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 AFE_2138 c3cb5d643be5c0b0803bc34972a39239 617 Gene3D G3DSA:1.10.390.60 185 454 2.3E-87 T 12-10-2018 AFE_2138 c3cb5d643be5c0b0803bc34972a39239 617 Pfam PF13180 PDZ domain 493 569 4.1E-9 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_2138 c3cb5d643be5c0b0803bc34972a39239 617 SUPERFAMILY SSF50156 496 571 1.84E-9 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFE_2138 c3cb5d643be5c0b0803bc34972a39239 617 SUPERFAMILY SSF55486 194 399 1.25E-11 T 12-10-2018 AFE_2138 c3cb5d643be5c0b0803bc34972a39239 617 PIRSF PIRSF016493 13 599 7.7E-181 T 12-10-2018 IPR024191 Peptidase M61 AFE_2138 c3cb5d643be5c0b0803bc34972a39239 617 Pfam PF05299 M61 glycyl aminopeptidase 274 390 1.7E-37 T 12-10-2018 IPR007963 Peptidase M61, catalytic domain AFE_2138 c3cb5d643be5c0b0803bc34972a39239 617 Gene3D G3DSA:2.30.42.10 493 598 3.7E-16 T 12-10-2018 AFE_2138 c3cb5d643be5c0b0803bc34972a39239 617 SMART SM00228 492 561 4.2E-4 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_2138 c3cb5d643be5c0b0803bc34972a39239 617 Gene3D G3DSA:2.60.40.3650 16 184 6.5E-53 T 12-10-2018 AFE_0196 3288b2646e1a3149a8032bf44910be25 156 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 82 95 4.5E-17 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFE_0196 3288b2646e1a3149a8032bf44910be25 156 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 99 113 4.5E-17 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFE_0196 3288b2646e1a3149a8032bf44910be25 156 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 114 127 4.5E-17 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFE_0196 3288b2646e1a3149a8032bf44910be25 156 SUPERFAMILY SSF51230 78 152 6.81E-24 T 12-10-2018 IPR011053 Single hybrid motif AFE_0196 3288b2646e1a3149a8032bf44910be25 156 Pfam PF00364 Biotin-requiring enzyme 80 152 1.5E-22 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFE_0196 3288b2646e1a3149a8032bf44910be25 156 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 109 126 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFE_0196 3288b2646e1a3149a8032bf44910be25 156 Gene3D G3DSA:2.40.50.100 76 152 5.1E-30 T 12-10-2018 AFE_0196 3288b2646e1a3149a8032bf44910be25 156 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 153 1.2E-48 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFE_1814 4017816bff4662e3c38e8b5a134f059c 116 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 40 83 2.7E-13 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFE_1814 4017816bff4662e3c38e8b5a134f059c 116 Gene3D G3DSA:1.20.1290.10 1 116 8.1E-28 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFE_1814 4017816bff4662e3c38e8b5a134f059c 116 SUPERFAMILY SSF69118 6 108 2.88E-24 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFE_1814 4017816bff4662e3c38e8b5a134f059c 116 Pfam PF02627 Carboxymuconolactone decarboxylase family 27 104 1.3E-17 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 Pfam PF01134 Glucose inhibited division protein A 6 394 4.5E-164 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 SMART SM01228 542 613 1.1E-36 T 12-10-2018 AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 Gene3D G3DSA:3.50.50.60 293 455 4.5E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 Gene3D G3DSA:3.50.50.60 1 217 5.1E-88 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 SUPERFAMILY SSF51905 4 258 4.13E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 5 617 5.8E-266 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 Gene3D G3DSA:1.10.150.570 565 618 1.8E-21 T 12-10-2018 AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 3 620 41.929 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 270 284 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 Pfam PF13932 GidA associated domain 399 612 1.1E-71 T 12-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 365 388 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 AFE_3214 bb3e06caf44069cd2322c93d1956d030 624 Gene3D G3DSA:1.10.10.1800 456 546 6.4E-22 T 12-10-2018 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 Gene3D G3DSA:1.10.10.10 234 312 4.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 3 316 37.127 T 12-10-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 SUPERFAMILY SSF88659 213 307 1.55E-24 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 Gene3D G3DSA:1.10.10.10 155 230 1.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 Pfam PF04542 Sigma-70 region 2 82 151 1.1E-20 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 Pfam PF04545 Sigma-70, region 4 250 303 9.9E-16 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 106 119 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 Pfam PF00140 Sigma-70 factor, region 1.2 44 77 9.4E-12 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 PRINTS PR00046 Major sigma-70 factor signature 275 290 2.4E-24 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 PRINTS PR00046 Major sigma-70 factor signature 106 119 2.4E-24 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 PRINTS PR00046 Major sigma-70 factor signature 130 138 2.4E-24 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 PRINTS PR00046 Major sigma-70 factor signature 254 266 2.4E-24 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 PRINTS PR00046 Major sigma-70 factor signature 290 301 2.4E-24 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 SUPERFAMILY SSF88659 155 228 5.23E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 78 304 4.4E-35 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 Gene3D G3DSA:1.20.120.1810 76 151 1.3E-39 T 12-10-2018 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 Gene3D G3DSA:1.20.120.1810 42 75 9.0E-6 T 12-10-2018 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 Pfam PF04539 Sigma-70 region 3 162 233 2.3E-19 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 42 316 1.9E-118 T 12-10-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 275 301 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_0470 6d0ad9a390be7e4c97ce527ed109cb99 317 SUPERFAMILY SSF88946 44 152 8.9E-46 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 Gene3D G3DSA:3.40.50.300 265 526 7.5E-65 T 12-10-2018 AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 Pfam PF00005 ABC transporter 19 169 6.9E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 SMART SM00382 328 498 2.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 SMART SM00382 28 215 2.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 Pfam PF12848 ABC transporter 208 281 3.3E-8 T 12-10-2018 IPR032781 ABC-transporter extension domain AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 Gene3D G3DSA:1.10.287.380 535 615 1.9E-15 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 Pfam PF00005 ABC transporter 320 453 2.2E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 SUPERFAMILY SSF52540 302 508 1.43E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 Pfam PF16326 ABC transporter C-terminal domain 545 612 1.2E-16 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 SUPERFAMILY SSF52540 5 221 1.08E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2893 c67818eba14f2ddbcd91f2892f17e376 620 Gene3D G3DSA:3.40.50.300 8 263 3.7E-58 T 12-10-2018 AFE_0452 3dd306fbaba9bb04c2705bd01e45937e 241 SUPERFAMILY SSF53067 116 239 1.04E-28 T 12-10-2018 AFE_0452 3dd306fbaba9bb04c2705bd01e45937e 241 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 1 235 1.1E-35 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFE_0452 3dd306fbaba9bb04c2705bd01e45937e 241 Gene3D G3DSA:3.30.420.490 116 227 1.5E-45 T 12-10-2018 AFE_0452 3dd306fbaba9bb04c2705bd01e45937e 241 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 241 16.215 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFE_0452 3dd306fbaba9bb04c2705bd01e45937e 241 SUPERFAMILY SSF53067 2 112 2.31E-7 T 12-10-2018 AFE_0452 3dd306fbaba9bb04c2705bd01e45937e 241 Pfam PF03309 Type III pantothenate kinase 2 195 1.0E-34 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFE_0452 3dd306fbaba9bb04c2705bd01e45937e 241 Gene3D G3DSA:3.30.420.40 3 234 1.5E-45 T 12-10-2018 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Pfam PF14520 Helix-hairpin-helix domain 448 502 1.8E-5 T 12-10-2018 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 PIRSF PIRSF001604 2 671 2.4E-235 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 15 663 5.3E-240 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 10 319 9.5E-112 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 SUPERFAMILY SSF56091 9 318 4.73E-109 T 12-10-2018 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 118 147 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 324 399 4.9E-33 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 333 348 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 SMART SM00292 593 670 7.7E-13 T 12-10-2018 IPR001357 BRCT domain AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 SMART SM00278 482 501 390.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 SMART SM00278 448 467 4.1 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 SMART SM00278 546 565 46.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 SMART SM00278 514 533 1000.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 SMART SM00532 7 450 6.4E-233 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 SUPERFAMILY SSF47781 405 585 1.48E-58 T 12-10-2018 IPR010994 RuvA domain 2-like AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Pfam PF12826 Helix-hairpin-helix motif 512 575 1.3E-22 T 12-10-2018 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Gene3D G3DSA:2.40.50.140 320 392 6.9E-31 T 12-10-2018 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 409 436 2.7E-9 T 12-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Gene3D G3DSA:3.30.470.90 74 319 1.0E-87 T 12-10-2018 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Gene3D G3DSA:1.10.150.20 434 507 3.7E-28 T 12-10-2018 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Gene3D G3DSA:2.20.70.80 393 432 2.5E-13 T 12-10-2018 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Hamap MF_01588 DNA ligase [ligA]. 7 667 50.918 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 SUPERFAMILY SSF50249 321 402 7.37E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 596 666 2.3E-13 T 12-10-2018 IPR001357 BRCT domain AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Gene3D G3DSA:1.10.150.20 508 584 7.9E-30 T 12-10-2018 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Gene3D G3DSA:1.10.287.610 9 73 1.9E-23 T 12-10-2018 AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 SUPERFAMILY SSF52113 590 669 2.94E-18 T 12-10-2018 IPR036420 BRCT domain superfamily AFE_0757 fb8251a1b51c834a4365e6e9ce05e9bf 671 Gene3D G3DSA:3.40.50.10190 585 669 8.9E-27 T 12-10-2018 IPR036420 BRCT domain superfamily AFE_1871 9e88d1e1633e636cb52e459927744db4 1015 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 159 813 3.6E-142 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_1871 9e88d1e1633e636cb52e459927744db4 1015 Pfam PF02811 PHP domain 6 96 6.8E-9 T 12-10-2018 IPR004013 PHP domain GO:0003824 AFE_1871 9e88d1e1633e636cb52e459927744db4 1015 Gene3D G3DSA:3.20.20.140 1 249 1.6E-41 T 12-10-2018 AFE_1871 9e88d1e1633e636cb52e459927744db4 1015 Pfam PF14579 Helix-hairpin-helix motif 762 847 3.9E-17 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_1871 9e88d1e1633e636cb52e459927744db4 1015 SUPERFAMILY SSF89550 5 188 1.86E-7 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFE_1871 9e88d1e1633e636cb52e459927744db4 1015 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 4 1015 12.925 T 12-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_1871 9e88d1e1633e636cb52e459927744db4 1015 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 271 684 2.2E-141 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 288 2.5E-140 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 SUPERFAMILY SSF51735 1 122 3.94E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 SUPERFAMILY SSF52210 123 287 4.06E-54 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 Gene3D G3DSA:3.40.50.720 2 123 5.4E-50 T 12-10-2018 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 SMART SM00881 4 100 9.2E-37 T 12-10-2018 IPR003781 CoA-binding GO:0048037 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 42.193 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 Pfam PF02629 CoA binding domain 7 99 4.9E-31 T 12-10-2018 IPR003781 CoA-binding GO:0048037 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.9E-34 T 12-10-2018 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.9E-34 T 12-10-2018 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.9E-34 T 12-10-2018 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.9E-34 T 12-10-2018 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 PIRSF PIRSF001553 1 290 2.0E-128 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 Gene3D G3DSA:3.40.50.261 124 288 6.4E-70 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFE_0427 bb7e6717201761fb5af01a8df75a9b01 290 Pfam PF00549 CoA-ligase 151 271 2.2E-19 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFE_1855 cbad7433eab3e06708d265d9c9c31beb 365 SUPERFAMILY SSF103473 4 351 3.01E-19 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_1855 cbad7433eab3e06708d265d9c9c31beb 365 Gene3D G3DSA:1.20.1250.20 2 166 1.9E-5 T 12-10-2018 AFE_1855 cbad7433eab3e06708d265d9c9c31beb 365 Gene3D G3DSA:1.20.1250.20 174 354 2.1E-18 T 12-10-2018 AFE_2368 5a30251571814057edad9c0a8c38289c 473 SUPERFAMILY SSF56954 4 455 7.06E-79 T 12-10-2018 AFE_2368 5a30251571814057edad9c0a8c38289c 473 Pfam PF02321 Outer membrane efflux protein 31 249 1.9E-30 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_2368 5a30251571814057edad9c0a8c38289c 473 Pfam PF02321 Outer membrane efflux protein 272 452 1.1E-22 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_2368 5a30251571814057edad9c0a8c38289c 473 Gene3D G3DSA:1.20.1600.10 26 458 7.4E-78 T 12-10-2018 AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 SMART SM00304 166 218 1.2E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 SUPERFAMILY SSF55874 294 417 7.6E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 SUPERFAMILY SSF158472 166 216 3.14E-5 T 12-10-2018 AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 SUPERFAMILY SSF47384 202 276 1.24E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 Gene3D G3DSA:1.10.287.130 163 273 4.5E-21 T 12-10-2018 AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 398 6.3E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 6.3E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 417 6.3E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 SMART SM00387 315 420 4.1E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 Gene3D G3DSA:3.30.565.10 301 419 1.5E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 SMART SM00388 219 278 1.6E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 418 9.1E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_3275 8c2182fe73260fab7fc75da6f45f2bd7 420 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 277 2.1E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0107 3f7d5edcb44540a34841eef49383d532 236 Pfam PF00072 Response regulator receiver domain 9 118 2.8E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0107 3f7d5edcb44540a34841eef49383d532 236 Gene3D G3DSA:3.40.50.2300 1 126 1.8E-36 T 12-10-2018 AFE_0107 3f7d5edcb44540a34841eef49383d532 236 SMART SM00448 7 117 8.6E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0107 3f7d5edcb44540a34841eef49383d532 236 SMART SM00862 156 232 1.8E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_0107 3f7d5edcb44540a34841eef49383d532 236 Gene3D G3DSA:1.10.10.10 131 235 8.3E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0107 3f7d5edcb44540a34841eef49383d532 236 SUPERFAMILY SSF46894 129 234 2.44E-25 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFE_0107 3f7d5edcb44540a34841eef49383d532 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 9.3E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_0107 3f7d5edcb44540a34841eef49383d532 236 SUPERFAMILY SSF52172 4 128 5.55E-40 T 12-10-2018 IPR011006 CheY-like superfamily AFE_2785 a0ff1da8f1809087bd936f9b41202859 384 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 41 384 8.3E-32 T 12-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 AFE_2785 a0ff1da8f1809087bd936f9b41202859 384 SUPERFAMILY SSF56935 118 318 5.98E-5 T 12-10-2018 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 330 349 1.5E-18 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 120 132 1.5E-18 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 236 249 1.5E-18 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 97 115 1.5E-18 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 537 550 1.5E-18 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PIRSF PIRSF001336 1 630 1.3E-236 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 274 287 - T 12-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 1 629 40.33 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 SUPERFAMILY SSF50621 400 561 3.84E-8 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 SUPERFAMILY SSF51419 65 342 9.65E-64 T 12-10-2018 IPR029066 PLP-binding barrel AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 TIGRFAM TIGR01273 speA: arginine decarboxylase 3 628 1.5E-237 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 Gene3D G3DSA:3.20.20.10 66 345 3.2E-219 T 12-10-2018 IPR029066 PLP-binding barrel AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01180 Arginine decarboxylase signature 193 215 3.8E-66 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01180 Arginine decarboxylase signature 484 509 3.8E-66 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01180 Arginine decarboxylase signature 169 190 3.8E-66 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01180 Arginine decarboxylase signature 89 103 3.8E-66 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01180 Arginine decarboxylase signature 143 158 3.8E-66 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01180 Arginine decarboxylase signature 459 480 3.8E-66 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01180 Arginine decarboxylase signature 320 337 3.8E-66 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01180 Arginine decarboxylase signature 537 558 3.8E-66 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 PRINTS PR01180 Arginine decarboxylase signature 65 80 3.8E-66 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 Gene3D G3DSA:2.40.37.10 12 562 3.2E-219 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 97 115 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 92 340 1.3E-45 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFE_1471 7d59ae376900cda7aa15d5c564587df7 637 Gene3D G3DSA:1.20.58.930 362 455 3.2E-219 T 12-10-2018 AFE_2705 288b5c3b3a94eed0be8221af04b5f2e0 323 SMART SM00858 49 109 2.2E-7 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFE_2705 288b5c3b3a94eed0be8221af04b5f2e0 323 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 111 240 1.1E-27 T 12-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain AFE_2705 288b5c3b3a94eed0be8221af04b5f2e0 323 Pfam PF08666 SAF domain 50 108 6.5E-6 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFE_2705 288b5c3b3a94eed0be8221af04b5f2e0 323 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 11 319 5.8E-44 T 12-10-2018 IPR017592 Pilus assembly, Flp-type CpaB AFE_1719 c1926f1ed4da0008cf4f8530c3808904 417 Gene3D G3DSA:1.10.10.2830 165 276 2.9E-13 T 12-10-2018 AFE_1719 c1926f1ed4da0008cf4f8530c3808904 417 SMART SM00470 67 178 9.0E-22 T 12-10-2018 IPR003115 ParB/Sulfiredoxin AFE_1719 c1926f1ed4da0008cf4f8530c3808904 417 Gene3D G3DSA:3.90.1530.30 80 147 4.7E-14 T 12-10-2018 AFE_1719 c1926f1ed4da0008cf4f8530c3808904 417 SUPERFAMILY SSF110849 71 214 3.31E-20 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily AFE_1719 c1926f1ed4da0008cf4f8530c3808904 417 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 66 225 2.8E-26 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 AFE_1719 c1926f1ed4da0008cf4f8530c3808904 417 Pfam PF02195 ParB-like nuclease domain 70 177 3.8E-19 T 12-10-2018 IPR003115 ParB/Sulfiredoxin AFE_1607 bd810925186b73ea28393defdab60db2 331 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 149 320 8.2E-23 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_1607 bd810925186b73ea28393defdab60db2 331 Gene3D G3DSA:2.40.30.170 41 325 4.2E-49 T 12-10-2018 AFE_1607 bd810925186b73ea28393defdab60db2 331 Gene3D G3DSA:2.40.50.100 52 239 4.2E-49 T 12-10-2018 AFE_1607 bd810925186b73ea28393defdab60db2 331 SUPERFAMILY SSF111369 44 324 2.35E-18 T 12-10-2018 AFE_1607 bd810925186b73ea28393defdab60db2 331 Gene3D G3DSA:1.10.287.470 86 205 4.2E-49 T 12-10-2018 AFE_2838 3ea0bf5d177c8c1a70857bdc08442c8b 435 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 29 48 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFE_2838 3ea0bf5d177c8c1a70857bdc08442c8b 435 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 23 402 1.5E-148 T 12-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFE_2838 3ea0bf5d177c8c1a70857bdc08442c8b 435 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 213 223 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFE_2838 3ea0bf5d177c8c1a70857bdc08442c8b 435 SUPERFAMILY SSF53448 20 382 6.1E-75 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2838 3ea0bf5d177c8c1a70857bdc08442c8b 435 Pfam PF00483 Nucleotidyl transferase 25 293 5.1E-62 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFE_2838 3ea0bf5d177c8c1a70857bdc08442c8b 435 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 115 123 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFE_2838 3ea0bf5d177c8c1a70857bdc08442c8b 435 Gene3D G3DSA:2.160.10.10 305 432 1.9E-34 T 12-10-2018 AFE_2838 3ea0bf5d177c8c1a70857bdc08442c8b 435 SUPERFAMILY SSF51161 314 415 6.1E-15 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFE_2838 3ea0bf5d177c8c1a70857bdc08442c8b 435 Gene3D G3DSA:3.90.550.10 13 304 6.4E-85 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2838 3ea0bf5d177c8c1a70857bdc08442c8b 435 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 20 428 50.365 T 12-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFE_2761 6f1706153416040c4cebf72fea820a32 443 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 24 437 1.1E-132 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFE_2761 6f1706153416040c4cebf72fea820a32 443 PIRSF PIRSF000445 22 443 2.6E-151 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFE_2761 6f1706153416040c4cebf72fea820a32 443 Gene3D G3DSA:3.40.50.720 182 332 6.3E-40 T 12-10-2018 AFE_2761 6f1706153416040c4cebf72fea820a32 443 SUPERFAMILY SSF69742 23 178 1.7E-47 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFE_2761 6f1706153416040c4cebf72fea820a32 443 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 341 438 4.2E-25 T 12-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFE_2761 6f1706153416040c4cebf72fea820a32 443 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 192 326 5.9E-40 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AFE_2761 6f1706153416040c4cebf72fea820a32 443 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 119 142 - T 12-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFE_2761 6f1706153416040c4cebf72fea820a32 443 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 28 176 7.6E-49 T 12-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFE_2761 6f1706153416040c4cebf72fea820a32 443 SUPERFAMILY SSF69075 337 438 5.89E-24 T 12-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFE_2761 6f1706153416040c4cebf72fea820a32 443 SUPERFAMILY SSF51735 182 335 1.51E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2761 6f1706153416040c4cebf72fea820a32 443 Gene3D G3DSA:3.30.460.30 22 178 2.0E-56 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFE_2761 6f1706153416040c4cebf72fea820a32 443 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 23 438 29.722 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFE_2275 0fd036f60317904a611cf00d3030df9b 242 SUPERFAMILY SSF74653 126 225 1.77E-21 T 12-10-2018 AFE_2275 0fd036f60317904a611cf00d3030df9b 242 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 166 224 2.7E-11 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 AFE_2275 0fd036f60317904a611cf00d3030df9b 242 Gene3D G3DSA:3.30.1150.10 115 239 7.0E-21 T 12-10-2018 AFE_2275 0fd036f60317904a611cf00d3030df9b 242 PRINTS PR01217 Proline rich extensin signature 118 135 1.2E-12 T 12-10-2018 AFE_2275 0fd036f60317904a611cf00d3030df9b 242 PRINTS PR01217 Proline rich extensin signature 93 109 1.2E-12 T 12-10-2018 AFE_2275 0fd036f60317904a611cf00d3030df9b 242 PRINTS PR01217 Proline rich extensin signature 64 85 1.2E-12 T 12-10-2018 AFE_2275 0fd036f60317904a611cf00d3030df9b 242 PRINTS PR01217 Proline rich extensin signature 45 57 1.2E-12 T 12-10-2018 AFE_2275 0fd036f60317904a611cf00d3030df9b 242 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 164 231 3.1E-14 T 12-10-2018 IPR006260 TonB/TolA, C-terminal AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 Gene3D G3DSA:1.25.40.20 103 259 6.7E-32 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 SUPERFAMILY SSF48403 37 248 1.15E-31 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 SMART SM00450 9 104 1.3E-22 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 Gene3D G3DSA:3.40.250.10 4 102 6.0E-24 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 Pfam PF00581 Rhodanese-like domain 13 99 5.7E-15 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 Pfam PF12796 Ankyrin repeats (3 copies) 116 197 9.9E-9 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 Pfam PF12796 Ankyrin repeats (3 copies) 198 250 4.3E-6 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 SUPERFAMILY SSF52821 4 107 7.48E-20 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 SMART SM00248 166 195 12.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 SMART SM00248 133 162 0.35 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 SMART SM00248 199 228 0.021 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFE_1502 85b5dcfd308fda8d7b0a5e3bda0418a6 260 SMART SM00248 232 258 1000.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFE_0954 264df0c1fc6b025b840a093d0a366be4 377 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 362 1.3E-92 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFE_0954 264df0c1fc6b025b840a093d0a366be4 377 PIRSF PIRSF000267 3 377 5.7E-103 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFE_0954 264df0c1fc6b025b840a093d0a366be4 377 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 4 370 4.8E-112 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFE_2824 5562ba06bd66cbe55018553ed543e0ff 134 Pfam PF01250 Ribosomal protein S6 3 90 2.1E-27 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2824 5562ba06bd66cbe55018553ed543e0ff 134 TIGRFAM TIGR00166 S6: ribosomal protein bS6 2 93 6.0E-33 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2824 5562ba06bd66cbe55018553ed543e0ff 134 SUPERFAMILY SSF54995 2 101 1.24E-35 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2824 5562ba06bd66cbe55018553ed543e0ff 134 Gene3D G3DSA:3.30.70.60 1 91 5.0E-31 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 AFE_2824 5562ba06bd66cbe55018553ed543e0ff 134 ProSitePatterns PS01048 Ribosomal protein S6 signature. 43 52 - T 12-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFE_2824 5562ba06bd66cbe55018553ed543e0ff 134 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.764 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFE_1330 0dc6a0f5f302c4264c4b0d09b9420b75 420 ProSitePatterns PS01007 Transposases, Mutator family, signature. 240 264 - T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 AFE_1330 0dc6a0f5f302c4264c4b0d09b9420b75 420 Pfam PF00872 Transposase, Mutator family 17 385 9.4E-70 T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 326 338 2.3E-63 T 12-10-2018 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 85 110 2.3E-63 T 12-10-2018 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 113 133 2.3E-63 T 12-10-2018 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 160 181 2.3E-63 T 12-10-2018 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 431 450 2.3E-63 T 12-10-2018 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 258 284 2.3E-63 T 12-10-2018 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 236 257 2.3E-63 T 12-10-2018 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 67 123 1.7E-23 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 10 649 1.2E-234 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 61 85 1.9E-9 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 276 298 1.9E-9 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 87 107 1.9E-9 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 430 452 1.9E-9 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFE_2619 8c788d2b80d8ec4f40d13027a68e6fc3 654 Pfam PF00361 Proton-conducting membrane transporter 136 416 4.0E-93 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 SUPERFAMILY SSF48163 345 496 3.01E-24 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 37 375 3.5E-111 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 Gene3D G3DSA:3.40.50.620 27 359 2.5E-118 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 PRINTS PR00987 Glutamyl-tRNA synthetase signature 53 64 2.2E-20 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 PRINTS PR00987 Glutamyl-tRNA synthetase signature 241 249 2.2E-20 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 PRINTS PR00987 Glutamyl-tRNA synthetase signature 225 235 2.2E-20 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 PRINTS PR00987 Glutamyl-tRNA synthetase signature 39 51 2.2E-20 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 PRINTS PR00987 Glutamyl-tRNA synthetase signature 68 81 2.2E-20 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 35 497 28.944 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 36 350 2.1E-78 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 Gene3D G3DSA:1.10.10.350 418 505 2.4E-16 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFE_2222 30e9503abfc6df88003039e1a40e7b30 508 SUPERFAMILY SSF52374 38 340 2.56E-100 T 12-10-2018 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 2 309 2.4E-128 T 12-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 Gene3D G3DSA:4.10.480.10 226 339 9.2E-40 T 12-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 224 304 4.2E-32 T 12-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 SUPERFAMILY SSF56770 49 306 1.23E-81 T 12-10-2018 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 Gene3D G3DSA:3.40.50.700 46 223 6.6E-62 T 12-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 14 36 0.0016 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 PIRSF PIRSF000310 3 353 2.2E-131 T 12-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 60 205 3.5E-28 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 281 294 1.1E-81 T 12-10-2018 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 157 181 1.1E-81 T 12-10-2018 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 186 209 1.1E-81 T 12-10-2018 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 68 92 1.1E-81 T 12-10-2018 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 114 137 1.1E-81 T 12-10-2018 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 45 67 1.1E-81 T 12-10-2018 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 211 228 1.1E-81 T 12-10-2018 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 229 247 1.1E-81 T 12-10-2018 AFE_3283 a4766224c7a65c04eff0cb39dfd85f7c 366 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 253 279 1.1E-81 T 12-10-2018 AFE_0125 e4c80445719eb49926c00f902fc506f4 198 Pfam PF02660 Glycerol-3-phosphate acyltransferase 13 187 2.6E-49 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFE_0125 e4c80445719eb49926c00f902fc506f4 198 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 8 196 19.984 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFE_0125 e4c80445719eb49926c00f902fc506f4 198 SMART SM01207 11 188 4.1E-73 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFE_0125 e4c80445719eb49926c00f902fc506f4 198 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 5 193 7.9E-57 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFE_0558 44b46484921b692e7c9b458f25dd2cbd 128 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 2 109 4.7E-19 T 12-10-2018 IPR018699 Protein of unknown function DUF2203 AFE_0256 c18806d2db32b650e6c9fbb22dd14c33 290 PRINTS PR00474 Glutamate 5-kinase family signature 60 74 7.7E-7 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_0256 c18806d2db32b650e6c9fbb22dd14c33 290 PRINTS PR00474 Glutamate 5-kinase family signature 188 215 7.7E-7 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_0256 c18806d2db32b650e6c9fbb22dd14c33 290 PRINTS PR00474 Glutamate 5-kinase family signature 238 258 7.7E-7 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_0256 c18806d2db32b650e6c9fbb22dd14c33 290 PIRSF PIRSF000728 14 288 3.0E-108 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFE_0256 c18806d2db32b650e6c9fbb22dd14c33 290 SUPERFAMILY SSF53633 11 288 5.76E-95 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_0256 c18806d2db32b650e6c9fbb22dd14c33 290 TIGRFAM TIGR00761 argB: acetylglutamate kinase 30 263 1.5E-75 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFE_0256 c18806d2db32b650e6c9fbb22dd14c33 290 Pfam PF00696 Amino acid kinase family 30 265 1.9E-47 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFE_0256 c18806d2db32b650e6c9fbb22dd14c33 290 Hamap MF_00082 Acetylglutamate kinase [argB]. 28 281 50.114 T 12-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFE_0256 c18806d2db32b650e6c9fbb22dd14c33 290 Gene3D G3DSA:3.40.1160.10 5 289 1.2E-100 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_3152 728eb5cb10fafdb3a4b00eb60aeb72c9 230 Pfam PF00034 Cytochrome c 62 131 2.2E-6 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3152 728eb5cb10fafdb3a4b00eb60aeb72c9 230 Pfam PF00034 Cytochrome c 148 230 2.4E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3152 728eb5cb10fafdb3a4b00eb60aeb72c9 230 SUPERFAMILY SSF46626 144 230 3.6E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_3152 728eb5cb10fafdb3a4b00eb60aeb72c9 230 SUPERFAMILY SSF46626 61 137 1.54E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_3152 728eb5cb10fafdb3a4b00eb60aeb72c9 230 PIRSF PIRSF000005 22 230 7.9E-63 T 12-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 AFE_3152 728eb5cb10fafdb3a4b00eb60aeb72c9 230 Gene3D G3DSA:1.10.760.10 147 230 5.7E-25 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_3152 728eb5cb10fafdb3a4b00eb60aeb72c9 230 Gene3D G3DSA:1.10.760.10 48 133 6.1E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_0190 87d61efc1b87b596f73aa3a6130ed1b8 141 Gene3D G3DSA:2.30.30.220 5 126 5.2E-42 T 12-10-2018 IPR036760 SspB-like superfamily AFE_0190 87d61efc1b87b596f73aa3a6130ed1b8 141 Pfam PF04386 Stringent starvation protein B 11 129 1.1E-28 T 12-10-2018 IPR007481 Stringent starvation protein B AFE_0190 87d61efc1b87b596f73aa3a6130ed1b8 141 PIRSF PIRSF005276 6 141 3.0E-42 T 12-10-2018 IPR007481 Stringent starvation protein B AFE_0190 87d61efc1b87b596f73aa3a6130ed1b8 141 SUPERFAMILY SSF101738 9 113 1.57E-36 T 12-10-2018 IPR036760 SspB-like superfamily AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 SUPERFAMILY SSF81886 615 902 5.75E-79 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 Pfam PF02810 SEC-C motif 894 912 4.1E-10 T 12-10-2018 IPR004027 SEC-C motif AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 Pfam PF07516 SecA Wing and Scaffold domain 612 824 1.2E-67 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 812 0.0 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 SUPERFAMILY SSF81767 227 356 2.62E-46 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 SMART SM00957 6 390 1.9E-293 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 Gene3D G3DSA:3.10.450.50 876 913 3.0E-8 T 12-10-2018 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 PRINTS PR00906 SecA protein signature 364 381 1.2E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 PRINTS PR00906 SecA protein signature 170 190 1.2E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 PRINTS PR00906 SecA protein signature 327 349 1.2E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 PRINTS PR00906 SecA protein signature 63 87 1.2E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 PRINTS PR00906 SecA protein signature 401 414 1.2E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 PRINTS PR00906 SecA protein signature 101 115 1.2E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 PRINTS PR00906 SecA protein signature 117 127 1.2E-71 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 Gene3D G3DSA:1.10.3060.10 616 827 5.4E-75 T 12-10-2018 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 SMART SM00958 228 346 3.9E-74 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 Pfam PF01043 SecA preprotein cross-linking domain 232 346 7.2E-41 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 827 20.192 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 SUPERFAMILY SSF52540 404 613 4.79E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 Gene3D G3DSA:3.40.50.300 23 403 6.1E-180 T 12-10-2018 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 ProSitePatterns PS01312 SecA family signature. 488 503 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 Gene3D G3DSA:3.40.50.300 405 615 1.0E-85 T 12-10-2018 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 Pfam PF07517 SecA DEAD-like domain 7 389 9.3E-133 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 SUPERFAMILY SSF52540 6 403 1.68E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0225 ff63ad95be36b3c2a7eb9f7f12c1a296 914 Gene3D G3DSA:3.90.1440.10 229 356 6.1E-180 T 12-10-2018 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 Gene3D G3DSA:2.30.30.30 118 195 4.2E-32 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 6.6E-57 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 Gene3D G3DSA:2.40.50.140 1 114 2.9E-43 T 12-10-2018 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 8.0E-31 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 PIRSF PIRSF002158 9 274 1.5E-100 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 SMART SM01383 42 118 1.5E-41 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.209 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 SUPERFAMILY SSF50104 126 272 1.14E-61 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFE_0330 2376f457888d442fadc38fd9d2afe207 274 Gene3D G3DSA:4.10.950.10 196 274 5.3E-36 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 SMART SM01382 124 252 7.6E-93 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 5 273 5.7E-125 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 AFE_0330 2376f457888d442fadc38fd9d2afe207 274 SUPERFAMILY SSF50249 3 125 1.47E-43 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1517 c0567de3a4e5e578eaea029d3850bc9e 463 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 61 68 - T 12-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 AFE_1517 c0567de3a4e5e578eaea029d3850bc9e 463 Gene3D G3DSA:3.40.50.1980 29 179 9.4E-49 T 12-10-2018 AFE_1517 c0567de3a4e5e578eaea029d3850bc9e 463 TIGRFAM TIGR01283 nifE: nitrogenase MoFe cofactor biosynthesis protein NifE 3 456 3.4E-200 T 12-10-2018 IPR005973 Nitrogenase MoFe cofactor biosynthesis protein NifE GO:0009399|GO:0065003 AFE_1517 c0567de3a4e5e578eaea029d3850bc9e 463 Gene3D G3DSA:3.40.50.12380 180 450 2.1E-110 T 12-10-2018 AFE_1517 c0567de3a4e5e578eaea029d3850bc9e 463 SUPERFAMILY SSF53807 19 454 3.6E-143 T 12-10-2018 AFE_1517 c0567de3a4e5e578eaea029d3850bc9e 463 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 43 441 1.1E-110 T 12-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 AFE_1517 c0567de3a4e5e578eaea029d3850bc9e 463 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 127 141 - T 12-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 426 29.287 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 SUPERFAMILY SSF47794 351 416 8.01E-16 T 12-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Pfam PF14520 Helix-hairpin-helix domain 434 488 2.9E-8 T 12-10-2018 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Pfam PF00575 S1 RNA binding domain 136 197 8.5E-8 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 SUPERFAMILY SSF69705 1 129 2.22E-38 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Gene3D G3DSA:2.40.50.140 138 200 7.2E-22 T 12-10-2018 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Gene3D G3DSA:1.10.150.20 355 423 1.6E-25 T 12-10-2018 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 SUPERFAMILY SSF54814 202 279 2.62E-29 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 SUPERFAMILY SSF47794 431 492 3.77E-13 T 12-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Pfam PF08529 NusA N-terminal domain 4 127 1.4E-35 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Gene3D G3DSA:3.30.1480.10 1 132 7.3E-40 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Gene3D G3DSA:3.30.300.20 201 279 7.5E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Gene3D G3DSA:1.10.150.20 433 491 1.2E-18 T 12-10-2018 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Pfam PF13184 NusA-like KH domain 232 299 4.1E-27 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 SUPERFAMILY SSF54814 281 344 1.05E-15 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 Gene3D G3DSA:3.30.300.20 280 349 2.8E-25 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 442 491 8.3E-15 T 12-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 415 1.5E-18 T 12-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 6 344 5.0E-122 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 SMART SM00316 136 202 2.9E-10 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_0390 05950340637aaf9a75dad2f2a85175c7 493 SUPERFAMILY SSF50249 136 201 9.8E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1761 14700354ce5ea1cde61c95bc2677cfad 78 Pfam PF04325 Protein of unknown function (DUF465) 29 75 2.8E-14 T 12-10-2018 IPR007420 Protein of unknown function DUF465 AFE_1761 14700354ce5ea1cde61c95bc2677cfad 78 Gene3D G3DSA:1.20.58.660 11 78 8.6E-21 T 12-10-2018 AFE_1949 db869e7a61d9fd8972af74a93ebf83e4 427 Gene3D G3DSA:1.20.1600.10 29 423 1.8E-57 T 12-10-2018 AFE_1949 db869e7a61d9fd8972af74a93ebf83e4 427 Pfam PF02321 Outer membrane efflux protein 39 221 2.4E-10 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_1949 db869e7a61d9fd8972af74a93ebf83e4 427 Pfam PF02321 Outer membrane efflux protein 248 420 2.7E-25 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_1949 db869e7a61d9fd8972af74a93ebf83e4 427 SUPERFAMILY SSF56954 18 420 4.97E-65 T 12-10-2018 AFE_2068 a565ef996f5816555100c9ae0f2e8346 272 Gene3D G3DSA:3.20.20.70 1 269 1.2E-93 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2068 a565ef996f5816555100c9ae0f2e8346 272 Pfam PF00290 Tryptophan synthase alpha chain 8 259 4.3E-81 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFE_2068 a565ef996f5816555100c9ae0f2e8346 272 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 263 32.493 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFE_2068 a565ef996f5816555100c9ae0f2e8346 272 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 255 9.9E-69 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFE_2068 a565ef996f5816555100c9ae0f2e8346 272 SUPERFAMILY SSF51366 1 249 6.22E-84 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFE_2068 a565ef996f5816555100c9ae0f2e8346 272 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFE_0287 ebfc1ac4edeb5dbed747b2b44810bf51 209 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 90 110 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFE_0287 ebfc1ac4edeb5dbed747b2b44810bf51 209 SMART SM00947 33 199 9.9E-57 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFE_0287 ebfc1ac4edeb5dbed747b2b44810bf51 209 Pfam PF00484 Carbonic anhydrase 41 194 8.8E-46 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 AFE_0287 ebfc1ac4edeb5dbed747b2b44810bf51 209 Gene3D G3DSA:3.40.1050.10 1 208 2.9E-68 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 AFE_0287 ebfc1ac4edeb5dbed747b2b44810bf51 209 SUPERFAMILY SSF53056 4 207 1.96E-60 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 Gene3D G3DSA:3.90.640.50 54 121 4.6E-67 T 12-10-2018 AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 Pfam PF04851 Type III restriction enzyme, res subunit 271 450 3.3E-36 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 748 1017 1.8E-57 T 12-10-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 Gene3D G3DSA:3.40.50.300 482 744 5.7E-75 T 12-10-2018 AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 32 739 1.6E-112 T 12-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 43 213 3.3E-28 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 SMART SM00487 269 479 1.7E-16 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 SUPERFAMILY SSF52540 240 457 2.97E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 Gene3D G3DSA:3.40.50.300 272 481 4.8E-60 T 12-10-2018 AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 Gene3D G3DSA:3.90.1570.50 30 263 4.6E-67 T 12-10-2018 AFE_2381 aff092309649f37d0e7b9351e52fe17f 1032 Gene3D G3DSA:1.20.58.910 745 843 1.3E-5 T 12-10-2018 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 Gene3D G3DSA:1.20.200.10 109 447 1.4E-144 T 12-10-2018 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 SUPERFAMILY SSF48557 8 458 4.24E-149 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 Pfam PF00206 Lyase 8 302 1.9E-79 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 5.6E-63 T 12-10-2018 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 233 257 5.6E-63 T 12-10-2018 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 312 331 5.6E-63 T 12-10-2018 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 5.6E-63 T 12-10-2018 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 5.6E-63 T 12-10-2018 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 5.6E-63 T 12-10-2018 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 Gene3D G3DSA:1.10.40.30 364 434 1.4E-144 T 12-10-2018 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 455 43.029 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 Pfam PF14698 Argininosuccinate lyase C-terminal 365 432 1.3E-24 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 2.6E-30 T 12-10-2018 IPR000362 Fumarate lyase family AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 2.6E-30 T 12-10-2018 IPR000362 Fumarate lyase family AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 2.6E-30 T 12-10-2018 IPR000362 Fumarate lyase family AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 2.6E-30 T 12-10-2018 IPR000362 Fumarate lyase family AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 TIGRFAM TIGR00838 argH: argininosuccinate lyase 5 457 8.6E-186 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFE_3277 527f0dfd4e7e3de8bfcc9315bcc767f8 462 Gene3D G3DSA:1.10.275.50 1 108 1.7E-38 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 68 475 1.0E-60 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 482 596 7.2E-27 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 SUPERFAMILY SSF81653 100 195 7.45E-28 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 Pfam PF00702 haloacid dehalogenase-like hydrolase 294 529 3.4E-27 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 TIGRFAM TIGR01647 ATPase-IIIA_H: plasma-membrane proton-efflux P-type ATPase 8 713 7.7E-202 T 12-10-2018 IPR006534 P-type ATPase, subfamily IIIA GO:0008553|GO:0016021|GO:0120029 KEGG: 00190+3.6.3.6 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 Gene3D G3DSA:3.40.50.1000 429 478 2.4E-10 T 12-10-2018 IPR023214 HAD superfamily AFE_3086 d7395784dc42e5d770938caf12e720eb 763 Pfam PF00122 E1-E2 ATPase 99 270 1.2E-43 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 Gene3D G3DSA:2.60.120.1500 97 187 1.3E-28 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 Gene3D G3DSA:3.40.1110.10 311 428 1.3E-18 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 Pfam PF00690 Cation transporter/ATPase, N-terminus 7 51 1.1E-9 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 677 698 2.6E-12 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 399 417 2.6E-12 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 547 572 2.6E-12 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 145 159 1.6E-38 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 551 1.6E-38 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 428 439 1.6E-38 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 450 460 1.6E-38 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 294 308 1.6E-38 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 516 535 1.6E-38 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 296 302 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 Gene3D G3DSA:1.20.1110.10 188 310 5.3E-21 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 Gene3D G3DSA:1.20.1110.10 479 756 3.4E-43 T 12-10-2018 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 SUPERFAMILY SSF81660 313 438 2.45E-11 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 SMART SM00831 2 61 3.1E-4 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 SUPERFAMILY SSF81665 5 759 1.57E-67 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFE_3086 d7395784dc42e5d770938caf12e720eb 763 SUPERFAMILY SSF56784 293 611 1.74E-39 T 12-10-2018 IPR036412 HAD-like superfamily AFE_2183 7dbd15dbb96419fa13ae6f439ffdd7a4 143 PRINTS PR01438 Universal stress protein signature 101 113 2.2E-12 T 12-10-2018 IPR006015 Universal stress protein A AFE_2183 7dbd15dbb96419fa13ae6f439ffdd7a4 143 PRINTS PR01438 Universal stress protein signature 119 141 2.2E-12 T 12-10-2018 IPR006015 Universal stress protein A AFE_2183 7dbd15dbb96419fa13ae6f439ffdd7a4 143 PRINTS PR01438 Universal stress protein signature 2 20 2.2E-12 T 12-10-2018 IPR006015 Universal stress protein A AFE_2183 7dbd15dbb96419fa13ae6f439ffdd7a4 143 Pfam PF00582 Universal stress protein family 1 141 5.6E-23 T 12-10-2018 IPR006016 UspA AFE_2183 7dbd15dbb96419fa13ae6f439ffdd7a4 143 SUPERFAMILY SSF52402 1 142 4.69E-29 T 12-10-2018 AFE_2183 7dbd15dbb96419fa13ae6f439ffdd7a4 143 Gene3D G3DSA:3.40.50.620 1 142 9.4E-30 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2776 4d7bf7b460fcfa302dc0dff2e27a3d1f 535 Gene3D G3DSA:3.40.50.970 3 177 1.5E-58 T 12-10-2018 AFE_2776 4d7bf7b460fcfa302dc0dff2e27a3d1f 535 Gene3D G3DSA:3.40.50.970 343 534 2.5E-39 T 12-10-2018 AFE_2776 4d7bf7b460fcfa302dc0dff2e27a3d1f 535 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 189 322 3.5E-15 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFE_2776 4d7bf7b460fcfa302dc0dff2e27a3d1f 535 Gene3D G3DSA:3.40.50.1220 178 337 4.5E-34 T 12-10-2018 AFE_2776 4d7bf7b460fcfa302dc0dff2e27a3d1f 535 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 524 1.1E-19 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFE_2776 4d7bf7b460fcfa302dc0dff2e27a3d1f 535 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 169 7.6E-35 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFE_2776 4d7bf7b460fcfa302dc0dff2e27a3d1f 535 SUPERFAMILY SSF52467 181 334 8.51E-47 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFE_2776 4d7bf7b460fcfa302dc0dff2e27a3d1f 535 SUPERFAMILY SSF52518 7 171 9.24E-36 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_2776 4d7bf7b460fcfa302dc0dff2e27a3d1f 535 SUPERFAMILY SSF52518 354 531 1.97E-29 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_3000 48946d48de07dc380c28be7ef0ff4430 355 SUPERFAMILY SSF51735 1 153 4.72E-13 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3000 48946d48de07dc380c28be7ef0ff4430 355 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 2 152 3.0E-10 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 AFE_3000 48946d48de07dc380c28be7ef0ff4430 355 SUPERFAMILY SSF56327 158 351 4.02E-18 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFE_3000 48946d48de07dc380c28be7ef0ff4430 355 Gene3D G3DSA:3.40.50.720 1 151 1.2E-18 T 12-10-2018 AFE_3000 48946d48de07dc380c28be7ef0ff4430 355 PIRSF PIRSF000102 255 353 1.5E-6 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFE_3000 48946d48de07dc380c28be7ef0ff4430 355 PIRSF PIRSF000102 1 245 3.0E-29 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFE_3000 48946d48de07dc380c28be7ef0ff4430 355 PRINTS PR00086 L-lactate dehydrogenase signature 180 193 2.3E-8 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFE_3000 48946d48de07dc380c28be7ef0ff4430 355 PRINTS PR00086 L-lactate dehydrogenase signature 150 168 2.3E-8 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFE_3000 48946d48de07dc380c28be7ef0ff4430 355 PRINTS PR00086 L-lactate dehydrogenase signature 128 148 2.3E-8 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFE_1459 c81c440386259109b948f7c22d986ae2 375 Pfam PF02684 Lipid-A-disaccharide synthetase 5 343 5.8E-87 T 12-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 AFE_1459 c81c440386259109b948f7c22d986ae2 375 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 6 356 2.7E-78 T 12-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 AFE_1459 c81c440386259109b948f7c22d986ae2 375 SUPERFAMILY SSF53756 57 370 3.52E-26 T 12-10-2018 AFE_2856 a9717235f90cd768744818524360421b 458 Pfam PF02978 Signal peptide binding domain 330 428 6.0E-34 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFE_2856 a9717235f90cd768744818524360421b 458 Gene3D G3DSA:3.40.50.300 90 286 4.7E-123 T 12-10-2018 AFE_2856 a9717235f90cd768744818524360421b 458 SUPERFAMILY SSF52540 42 354 5.76E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2856 a9717235f90cd768744818524360421b 458 SUPERFAMILY SSF47446 299 433 5.89E-46 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFE_2856 a9717235f90cd768744818524360421b 458 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 431 2.0E-181 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 AFE_2856 a9717235f90cd768744818524360421b 458 SMART SM00963 1 86 1.9E-36 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFE_2856 a9717235f90cd768744818524360421b 458 SMART SM00382 99 247 1.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2856 a9717235f90cd768744818524360421b 458 Gene3D G3DSA:1.10.260.30 329 449 4.2E-44 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFE_2856 a9717235f90cd768744818524360421b 458 Gene3D G3DSA:1.20.120.140 4 307 4.7E-123 T 12-10-2018 AFE_2856 a9717235f90cd768744818524360421b 458 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.1E-22 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFE_2856 a9717235f90cd768744818524360421b 458 Pfam PF00448 SRP54-type protein, GTPase domain 100 297 1.2E-72 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFE_2856 a9717235f90cd768744818524360421b 458 SMART SM00962 100 297 7.0E-113 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFE_2856 a9717235f90cd768744818524360421b 458 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 443 33.662 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 Pfam PF13437 HlyD family secretion protein 310 430 2.6E-19 T 12-10-2018 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 355 379 3.9E-38 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 322 343 3.9E-38 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 55 78 3.9E-38 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 444 464 3.9E-38 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 97 117 3.9E-38 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 379 402 3.9E-38 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 429 444 3.9E-38 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 Gene3D G3DSA:1.10.287.470 119 186 3.0E-7 T 12-10-2018 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 Gene3D G3DSA:2.40.30.170 324 447 4.9E-14 T 12-10-2018 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 49 462 4.4E-99 T 12-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 Gene3D G3DSA:2.40.50.100 89 118 3.0E-7 T 12-10-2018 AFE_2692 f7ea968c024aa1546d178a111bf19380 465 Pfam PF13533 Biotin-lipoyl like 90 133 8.1E-7 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain AFE_0599 9f2ef32f9d215d5427d3db6eaf9d11ef 291 Gene3D G3DSA:3.10.580.10 46 192 9.3E-52 T 12-10-2018 AFE_0599 9f2ef32f9d215d5427d3db6eaf9d11ef 291 SUPERFAMILY SSF54631 59 199 6.19E-33 T 12-10-2018 AFE_0599 9f2ef32f9d215d5427d3db6eaf9d11ef 291 SUPERFAMILY SSF56176 199 280 1.64E-20 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFE_0599 9f2ef32f9d215d5427d3db6eaf9d11ef 291 SMART SM00116 73 122 0.78 T 12-10-2018 IPR000644 CBS domain AFE_0599 9f2ef32f9d215d5427d3db6eaf9d11ef 291 SMART SM00116 136 184 1.5 T 12-10-2018 IPR000644 CBS domain AFE_0599 9f2ef32f9d215d5427d3db6eaf9d11ef 291 SMART SM01091 200 278 2.7E-25 T 12-10-2018 IPR005170 Transporter-associated domain AFE_0599 9f2ef32f9d215d5427d3db6eaf9d11ef 291 Pfam PF00571 CBS domain 136 184 1.9E-5 T 12-10-2018 IPR000644 CBS domain AFE_0599 9f2ef32f9d215d5427d3db6eaf9d11ef 291 Pfam PF00571 CBS domain 64 119 9.6E-6 T 12-10-2018 IPR000644 CBS domain AFE_0599 9f2ef32f9d215d5427d3db6eaf9d11ef 291 Gene3D G3DSA:3.30.465.10 197 278 3.6E-25 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFE_0599 9f2ef32f9d215d5427d3db6eaf9d11ef 291 Pfam PF03471 Transporter associated domain 202 277 1.9E-19 T 12-10-2018 IPR005170 Transporter-associated domain AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 Gene3D G3DSA:1.20.1640.10 15 504 7.4E-202 T 12-10-2018 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 SUPERFAMILY SSF82866 294 494 8.5E-37 T 12-10-2018 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 PRINTS PR00702 Acriflavin resistance protein family signature 541 558 2.9E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 2.9E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 2.9E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 PRINTS PR00702 Acriflavin resistance protein family signature 443 466 2.9E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 PRINTS PR00702 Acriflavin resistance protein family signature 468 491 2.9E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 2.9E-35 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 Gene3D G3DSA:3.30.2090.10 177 274 7.4E-202 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 Gene3D G3DSA:1.20.1640.10 505 1007 7.4E-202 T 12-10-2018 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 SUPERFAMILY SSF82714 180 268 1.96E-7 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 Pfam PF00873 AcrB/AcrD/AcrF family 10 1007 8.7E-176 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 SUPERFAMILY SSF82714 718 790 8.5E-8 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 Gene3D G3DSA:3.30.70.1430 558 658 7.4E-202 T 12-10-2018 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 SUPERFAMILY SSF82866 794 1013 1.06E-36 T 12-10-2018 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 SUPERFAMILY SSF82693 41 123 1.31E-10 T 12-10-2018 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 Gene3D G3DSA:3.30.70.1440 659 853 7.4E-202 T 12-10-2018 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 Gene3D G3DSA:3.30.70.1430 41 803 7.4E-202 T 12-10-2018 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 SUPERFAMILY SSF82693 555 641 2.72E-8 T 12-10-2018 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 Gene3D G3DSA:3.30.70.1320 130 328 7.4E-202 T 12-10-2018 AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 Gene3D G3DSA:3.30.2090.10 709 795 7.4E-202 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2043 3202f45532d4bac548775622e23cfb7c 1032 SUPERFAMILY SSF82693 133 328 3.66E-14 T 12-10-2018 AFE_2339 47163b7ab4ca0eb185e8a2a00c07a594 148 Pfam PF09424 Yqey-like protein 4 146 5.0E-51 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 AFE_2339 47163b7ab4ca0eb185e8a2a00c07a594 148 Gene3D G3DSA:1.10.1510.10 1 90 4.3E-31 T 12-10-2018 AFE_2339 47163b7ab4ca0eb185e8a2a00c07a594 148 Gene3D G3DSA:1.10.10.410 91 147 3.9E-14 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AFE_2339 47163b7ab4ca0eb185e8a2a00c07a594 148 SUPERFAMILY SSF89095 1 146 1.2E-39 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 AFE_2570 852f04f98c3f508a69308c732838d5ae 317 Pfam PF04055 Radical SAM superfamily 87 247 4.5E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_2570 852f04f98c3f508a69308c732838d5ae 317 PIRSF PIRSF005963 2 316 2.7E-126 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFE_2570 852f04f98c3f508a69308c732838d5ae 317 Gene3D G3DSA:3.20.20.70 79 308 3.2E-15 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2570 852f04f98c3f508a69308c732838d5ae 317 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 29 69 1.3E-7 T 12-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFE_2570 852f04f98c3f508a69308c732838d5ae 317 TIGRFAM TIGR00510 lipA: lipoyl synthase 30 313 2.3E-126 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFE_2570 852f04f98c3f508a69308c732838d5ae 317 SMART SM00729 80 289 3.6E-7 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFE_2570 852f04f98c3f508a69308c732838d5ae 317 SUPERFAMILY SSF102114 47 309 1.19E-62 T 12-10-2018 AFE_2570 852f04f98c3f508a69308c732838d5ae 317 Hamap MF_00206 Lipoyl synthase [lipA]. 1 317 145.317 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 599 2.2E-286 T 12-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 SUPERFAMILY SSF54980 399 513 1.25E-29 T 12-10-2018 IPR035647 EF-G domain III/V-like AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 SUPERFAMILY SSF50447 151 299 1.54E-30 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 Pfam PF00679 Elongation factor G C-terminus 398 482 1.1E-22 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 Gene3D G3DSA:3.40.50.300 2 198 2.5E-64 T 12-10-2018 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 PRINTS PR00315 GTP-binding elongation factor signature 87 98 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 PRINTS PR00315 GTP-binding elongation factor signature 123 132 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 PRINTS PR00315 GTP-binding elongation factor signature 51 59 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 PRINTS PR00315 GTP-binding elongation factor signature 71 81 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 PRINTS PR00315 GTP-binding elongation factor signature 7 20 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 SUPERFAMILY SSF52540 3 207 1.8E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 Pfam PF00009 Elongation factor Tu GTP binding domain 4 194 4.5E-55 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 136 3.5E-23 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 SUPERFAMILY SSF54980 303 388 1.26E-14 T 12-10-2018 IPR035647 EF-G domain III/V-like AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 Pfam PF03144 Elongation factor Tu domain 2 219 289 2.8E-10 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 Gene3D G3DSA:3.30.70.870 307 590 1.6E-129 T 12-10-2018 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 Gene3D G3DSA:2.40.30.10 200 300 3.6E-30 T 12-10-2018 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 Gene3D G3DSA:2.40.50.250 483 599 1.6E-129 T 12-10-2018 AFE_2740 6299704ef5c3ce9c89a6ecc9a7456640 605 Gene3D G3DSA:3.30.70.240 390 482 1.6E-129 T 12-10-2018 AFE_0248 65fff5cee1360ca48a2b51d004d8c761 241 Gene3D G3DSA:2.30.210.20 11 67 1.5E-22 T 12-10-2018 AFE_0248 65fff5cee1360ca48a2b51d004d8c761 241 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 42 211 5.5E-71 T 12-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 AFE_0248 65fff5cee1360ca48a2b51d004d8c761 241 Gene3D G3DSA:3.40.630.70 68 239 1.2E-63 T 12-10-2018 AFE_0248 65fff5cee1360ca48a2b51d004d8c761 241 SUPERFAMILY SSF55729 13 231 7.95E-86 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_0248 65fff5cee1360ca48a2b51d004d8c761 241 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 42 223 5.6E-61 T 12-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 AFE_0248 65fff5cee1360ca48a2b51d004d8c761 241 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 241 89.87 T 12-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 SMART SM01086 654 743 2.3E-30 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 517 535 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 654 733 6.3E-23 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 Pfam PF07724 AAA domain (Cdc48 subfamily) 485 647 1.6E-45 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 733 0.0 T 12-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 Gene3D G3DSA:1.10.8.60 355 437 1.2E-30 T 12-10-2018 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 341 7.0E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 Gene3D G3DSA:3.40.50.300 438 652 4.9E-76 T 12-10-2018 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 SMART SM00382 205 349 2.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 SMART SM00382 486 651 4.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 SUPERFAMILY SSF81923 1 141 7.06E-51 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 SUPERFAMILY SSF52540 438 736 1.96E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 Gene3D G3DSA:3.40.50.300 165 354 1.5E-66 T 12-10-2018 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 561 579 4.3E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 490 508 4.3E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 594 608 4.3E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 532 550 4.3E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 61 5.8E-12 T 12-10-2018 IPR004176 Clp, N-terminal AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 Gene3D G3DSA:1.10.8.60 654 751 3.4E-27 T 12-10-2018 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 301 313 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 Gene3D G3DSA:1.10.1780.10 1 142 3.8E-36 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFE_0520 4d01a646c4d57b6f2dd40e78207f72c8 752 SUPERFAMILY SSF52540 167 422 1.98E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1897 c53a65974acfc92e0ba4c9d2c4349952 345 SUPERFAMILY SSF56042 172 338 4.93E-53 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFE_1897 c53a65974acfc92e0ba4c9d2c4349952 345 Gene3D G3DSA:3.30.1330.10 7 170 4.1E-69 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFE_1897 c53a65974acfc92e0ba4c9d2c4349952 345 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 7 333 4.0E-134 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_1897 c53a65974acfc92e0ba4c9d2c4349952 345 Pfam PF00586 AIR synthase related protein, N-terminal domain 61 164 2.5E-16 T 12-10-2018 IPR016188 PurM-like, N-terminal domain AFE_1897 c53a65974acfc92e0ba4c9d2c4349952 345 Gene3D G3DSA:3.90.650.10 171 342 3.1E-62 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFE_1897 c53a65974acfc92e0ba4c9d2c4349952 345 SUPERFAMILY SSF55326 7 169 4.93E-52 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFE_1897 c53a65974acfc92e0ba4c9d2c4349952 345 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 344 45.163 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_1897 c53a65974acfc92e0ba4c9d2c4349952 345 Pfam PF02769 AIR synthase related protein, C-terminal domain 176 339 2.3E-31 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFE_2494 72ca8518306895a4d16613e36acf0461 119 Gene3D G3DSA:3.30.70.2340 1 99 2.7E-25 T 12-10-2018 AFE_2494 72ca8518306895a4d16613e36acf0461 119 Pfam PF12112 Protein of unknown function (DUF3579) 3 85 7.6E-19 T 12-10-2018 IPR021969 Protein of unknown function DUF3579 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 SUPERFAMILY SSF46689 140 188 5.82E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 SUPERFAMILY SSF48150 306 487 2.36E-38 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 SUPERFAMILY SSF55945 200 298 3.77E-29 T 12-10-2018 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 140 182 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 Gene3D G3DSA:1.10.10.60 84 197 8.3E-20 T 12-10-2018 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 Pfam PF12833 Helix-turn-helix domain 109 186 4.4E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 Gene3D G3DSA:3.40.10.10 1 75 2.9E-29 T 12-10-2018 IPR035451 Ada-like domain superfamily AFE_2799 cacd8e6aed96724db28f37966db2e142 496 Gene3D G3DSA:1.10.340.30 318 439 2.5E-29 T 12-10-2018 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 Gene3D G3DSA:1.10.1670.10 441 495 1.9E-12 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 SMART SM00478 327 489 3.8E-14 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 SMART SM00342 103 186 6.1E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 Pfam PF02805 Metal binding domain of Ada 10 74 2.9E-29 T 12-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 SUPERFAMILY SSF57884 4 83 1.02E-32 T 12-10-2018 IPR035451 Ada-like domain superfamily AFE_2799 cacd8e6aed96724db28f37966db2e142 496 SMART SM01009 200 317 1.7E-53 T 12-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal AFE_2799 cacd8e6aed96724db28f37966db2e142 496 SUPERFAMILY SSF46689 87 134 1.67E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_2799 cacd8e6aed96724db28f37966db2e142 496 Gene3D G3DSA:3.30.310.20 200 317 1.5E-33 T 12-10-2018 IPR037046 DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily AFE_2799 cacd8e6aed96724db28f37966db2e142 496 Pfam PF06029 AlkA N-terminal domain 200 317 2.9E-37 T 12-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal AFE_2595 5555b93df201f9b2acad34903508f7b1 124 Pfam PF01638 HxlR-like helix-turn-helix 15 101 6.8E-35 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFE_2595 5555b93df201f9b2acad34903508f7b1 124 SUPERFAMILY SSF46785 4 107 9.49E-37 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2595 5555b93df201f9b2acad34903508f7b1 124 Gene3D G3DSA:1.10.10.10 1 122 1.1E-43 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2818 15bf9d355c69c9374f302d3134110a14 364 SUPERFAMILY SSF50621 233 363 8.02E-38 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 PRINTS PR00992 Alanine racemase signature 272 287 8.9E-58 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 PRINTS PR00992 Alanine racemase signature 123 135 8.9E-58 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 PRINTS PR00992 Alanine racemase signature 345 358 8.9E-58 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 PRINTS PR00992 Alanine racemase signature 198 225 8.9E-58 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 PRINTS PR00992 Alanine racemase signature 63 81 8.9E-58 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 PRINTS PR00992 Alanine racemase signature 293 310 8.9E-58 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 PRINTS PR00992 Alanine racemase signature 157 168 8.9E-58 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 PRINTS PR00992 Alanine racemase signature 255 270 8.9E-58 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 PRINTS PR00992 Alanine racemase signature 27 43 8.9E-58 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 Pfam PF00842 Alanine racemase, C-terminal domain 239 361 6.2E-35 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 Pfam PF01168 Alanine racemase, N-terminal domain 9 225 5.0E-64 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 Gene3D G3DSA:2.40.37.10 9 360 5.0E-110 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 SMART SM01005 239 363 2.8E-44 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 SUPERFAMILY SSF51419 9 240 8.9E-66 T 12-10-2018 IPR029066 PLP-binding barrel AFE_2818 15bf9d355c69c9374f302d3134110a14 364 Gene3D G3DSA:3.20.20.10 11 223 5.0E-110 T 12-10-2018 IPR029066 PLP-binding barrel AFE_2818 15bf9d355c69c9374f302d3134110a14 364 Hamap MF_01201 Alanine racemase. 2 363 31.27 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_2818 15bf9d355c69c9374f302d3134110a14 364 TIGRFAM TIGR00492 alr: alanine racemase 4 363 1.7E-95 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_1575 9456ef912c5036e3a5208815c023b3fb 760 SUPERFAMILY SSF52540 146 364 5.98E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1575 9456ef912c5036e3a5208815c023b3fb 760 SMART SM00487 148 359 1.3E-19 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_1575 9456ef912c5036e3a5208815c023b3fb 760 Gene3D G3DSA:3.90.1570.30 1 129 3.0E-37 T 12-10-2018 AFE_1575 9456ef912c5036e3a5208815c023b3fb 760 Pfam PF00271 Helicase conserved C-terminal domain 409 515 9.2E-6 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_1575 9456ef912c5036e3a5208815c023b3fb 760 SUPERFAMILY SSF52540 281 531 1.32E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1575 9456ef912c5036e3a5208815c023b3fb 760 Pfam PF04851 Type III restriction enzyme, res subunit 150 323 3.8E-36 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFE_1575 9456ef912c5036e3a5208815c023b3fb 760 Gene3D G3DSA:3.40.50.300 135 339 6.5E-74 T 12-10-2018 AFE_1575 9456ef912c5036e3a5208815c023b3fb 760 Pfam PF08463 EcoEI R protein C-terminal 603 759 1.9E-25 T 12-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 AFE_1575 9456ef912c5036e3a5208815c023b3fb 760 Gene3D G3DSA:3.40.50.300 340 553 2.7E-48 T 12-10-2018 AFE_2466 7a031d3645b79bf5fb058934a081a0a5 518 Gene3D G3DSA:3.30.1490.20 308 368 1.1E-5 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFE_2466 7a031d3645b79bf5fb058934a081a0a5 518 Pfam PF14401 RimK-like ATPgrasp N-terminal domain 28 174 8.3E-39 T 12-10-2018 IPR025839 RimK-like ATPgrasp N-terminal domain AFE_2466 7a031d3645b79bf5fb058934a081a0a5 518 Gene3D G3DSA:3.30.470.20 370 486 1.1E-15 T 12-10-2018 AFE_2466 7a031d3645b79bf5fb058934a081a0a5 518 SUPERFAMILY SSF56059 281 482 2.95E-34 T 12-10-2018 AFE_2466 7a031d3645b79bf5fb058934a081a0a5 518 Gene3D G3DSA:3.40.50.20 217 304 1.4E-6 T 12-10-2018 AFE_1023 7f271ffe1450c37a801647af6a27e1b8 454 Pfam PF14239 RRXRR protein 3 190 4.5E-65 T 12-10-2018 IPR025938 RRXRR domain AFE_1023 7f271ffe1450c37a801647af6a27e1b8 454 SMART SM00507 196 247 8.6E-14 T 12-10-2018 IPR003615 HNH nuclease AFE_1023 7f271ffe1450c37a801647af6a27e1b8 454 Pfam PF01844 HNH endonuclease 209 252 1.6E-11 T 12-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 AFE_1023 7f271ffe1450c37a801647af6a27e1b8 454 Gene3D G3DSA:3.30.40.60 178 302 1.5E-16 T 12-10-2018 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 SUPERFAMILY SSF52009 130 248 7.46E-31 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 Gene3D G3DSA:3.50.30.10 7 235 1.2E-68 T 12-10-2018 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 PIRSF PIRSF000732 1 563 1.3E-197 T 12-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 504 516 7.6E-23 T 12-10-2018 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 451 466 7.6E-23 T 12-10-2018 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 295 314 7.6E-23 T 12-10-2018 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 468 483 7.6E-23 T 12-10-2018 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 255 544 6.8E-96 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 SUPERFAMILY SSF47831 28 146 7.32E-28 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 Gene3D G3DSA:1.10.274.10 24 149 1.2E-68 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 Pfam PF05524 PEP-utilising enzyme, N-terminal 7 128 5.9E-25 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 Pfam PF00391 PEP-utilising enzyme, mobile domain 156 227 3.1E-22 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 451 469 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 558 1.9E-154 T 12-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 186 197 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 SUPERFAMILY SSF51621 250 545 5.76E-95 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFE_3018 afc794ae7d5192e137af76dbd968e665 570 Gene3D G3DSA:3.20.20.60 236 565 1.9E-108 T 12-10-2018 AFE_2986 1971547b68bd212899e1727a0cf78e84 145 Pfam PF13673 Acetyltransferase (GNAT) domain 20 143 1.0E-21 T 12-10-2018 IPR000182 GNAT domain AFE_2986 1971547b68bd212899e1727a0cf78e84 145 Gene3D G3DSA:3.40.630.30 10 144 4.1E-36 T 12-10-2018 AFE_2986 1971547b68bd212899e1727a0cf78e84 145 SUPERFAMILY SSF55729 4 143 6.1E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_0666 fc85d258d05660d102f64e061fa2ee05 109 Pfam PF03795 YCII-related domain 10 103 1.6E-24 T 12-10-2018 IPR005545 YCII-related AFE_0666 fc85d258d05660d102f64e061fa2ee05 109 Gene3D G3DSA:3.30.70.1060 7 107 2.1E-33 T 12-10-2018 AFE_0666 fc85d258d05660d102f64e061fa2ee05 109 SUPERFAMILY SSF54909 9 106 1.07E-27 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFE_3197 6a48f28d194c83bb748595b8e5a72721 551 SUPERFAMILY SSF52540 118 332 1.62E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3197 6a48f28d194c83bb748595b8e5a72721 551 Gene3D G3DSA:3.40.50.300 111 277 3.3E-6 T 12-10-2018 AFE_3197 6a48f28d194c83bb748595b8e5a72721 551 Pfam PF13401 AAA domain 120 267 2.1E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1940 12f3e143616feda9f209263c25d3f43b 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 310 5.8E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFE_1940 12f3e143616feda9f209263c25d3f43b 318 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 5 314 2.8E-75 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 AFE_1940 12f3e143616feda9f209263c25d3f43b 318 SUPERFAMILY SSF161098 24 308 2.06E-30 T 12-10-2018 IPR035906 MetI-like superfamily AFE_1940 12f3e143616feda9f209263c25d3f43b 318 Gene3D G3DSA:1.10.3720.10 70 316 2.1E-31 T 12-10-2018 IPR035906 MetI-like superfamily AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 Gene3D G3DSA:3.40.50.300 222 379 5.1E-99 T 12-10-2018 AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 Pfam PF01926 50S ribosome-binding GTPase 223 326 6.1E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 13 451 8.5E-94 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 Gene3D G3DSA:3.30.1360.120 2 126 6.7E-41 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 SUPERFAMILY SSF116878 126 451 3.01E-42 T 12-10-2018 AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 7 451 30.943 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 Pfam PF12631 MnmE helical domain 128 448 2.0E-49 T 12-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 Pfam PF10396 GTP-binding protein TrmE N-terminus 8 125 1.0E-34 T 12-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 SUPERFAMILY SSF52540 78 368 1.65E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 222 350 1.1E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_0031 0e7a3ed4fb0cbbce686977080b21c2a7 451 Gene3D G3DSA:1.20.120.430 127 451 5.1E-99 T 12-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 AFE_2145 dc04e10ca4762a88215c57ad8f00dcf3 202 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 186 28.777 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFE_2145 dc04e10ca4762a88215c57ad8f00dcf3 202 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 185 9.5E-43 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFE_2145 dc04e10ca4762a88215c57ad8f00dcf3 202 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 4 96 21.385 T 12-10-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFE_2145 dc04e10ca4762a88215c57ad8f00dcf3 202 SUPERFAMILY SSF50715 4 195 1.92E-53 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFE_2145 dc04e10ca4762a88215c57ad8f00dcf3 202 Gene3D G3DSA:2.40.240.10 2 96 5.8E-27 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFE_2145 dc04e10ca4762a88215c57ad8f00dcf3 202 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 102 189 1.1E-25 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain AFE_2145 dc04e10ca4762a88215c57ad8f00dcf3 202 Gene3D G3DSA:2.170.120.20 99 196 1.2E-23 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal AFE_2145 dc04e10ca4762a88215c57ad8f00dcf3 202 Pfam PF01386 Ribosomal L25p family 6 93 4.3E-25 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFE_2145 dc04e10ca4762a88215c57ad8f00dcf3 202 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 8 96 2.0E-14 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 Gene3D G3DSA:2.170.230.10 133 202 4.1E-65 T 12-10-2018 AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 203 222 3.9E-24 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 58 74 3.9E-24 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 122 134 3.9E-24 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 Pfam PF10502 Signal peptidase, peptidase S26 201 240 2.7E-5 T 12-10-2018 IPR019533 Peptidase S26 AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 43 243 2.7E-50 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 ProSitePatterns PS00501 Signal peptidases I serine active site. 67 74 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 SUPERFAMILY SSF51306 56 257 2.88E-66 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 ProSitePatterns PS00760 Signal peptidases I lysine active site. 124 136 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 Pfam PF00717 Peptidase S24-like 64 146 1.3E-20 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFE_1398 f53b9b114e843158fc63bf1d46eae6e2 263 Gene3D G3DSA:2.10.109.10 56 243 4.1E-65 T 12-10-2018 AFE_0719 f8861f72cc45a0e462c5f48c79294154 469 Gene3D G3DSA:1.20.1740.10 8 458 5.8E-37 T 12-10-2018 AFE_0719 f8861f72cc45a0e462c5f48c79294154 469 PIRSF PIRSF006060 1 462 1.3E-47 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_0719 f8861f72cc45a0e462c5f48c79294154 469 Pfam PF13520 Amino acid permease 15 446 8.4E-23 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_0333 5d445c29cfb41854ce1d67db53705367 228 Gene3D G3DSA:3.30.1140.32 115 215 1.8E-43 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0333 5d445c29cfb41854ce1d67db53705367 228 Pfam PF07650 KH domain 45 118 1.8E-20 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0333 5d445c29cfb41854ce1d67db53705367 228 SMART SM00322 67 132 3.9E-10 T 12-10-2018 IPR004087 K Homology domain GO:0003676 AFE_0333 5d445c29cfb41854ce1d67db53705367 228 Gene3D G3DSA:3.30.300.20 25 114 3.6E-27 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFE_0333 5d445c29cfb41854ce1d67db53705367 228 Pfam PF00189 Ribosomal protein S3, C-terminal domain 127 209 7.6E-39 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0333 5d445c29cfb41854ce1d67db53705367 228 SUPERFAMILY SSF54814 10 113 9.16E-36 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFE_0333 5d445c29cfb41854ce1d67db53705367 228 ProSitePatterns PS00548 Ribosomal protein S3 signature. 170 204 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0333 5d445c29cfb41854ce1d67db53705367 228 SUPERFAMILY SSF54821 115 213 1.57E-39 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0333 5d445c29cfb41854ce1d67db53705367 228 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 9 216 3.6E-92 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 AFE_0333 5d445c29cfb41854ce1d67db53705367 228 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 9 213 38.219 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 AFE_1889 990e709c697326a0e29463441e6ae337 431 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 431 205.332 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFE_1889 990e709c697326a0e29463441e6ae337 431 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 13 20 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFE_1889 990e709c697326a0e29463441e6ae337 431 Gene3D G3DSA:3.90.170.10 269 431 1.4E-65 T 12-10-2018 AFE_1889 990e709c697326a0e29463441e6ae337 431 Gene3D G3DSA:3.40.440.10 8 251 1.1E-95 T 12-10-2018 AFE_1889 990e709c697326a0e29463441e6ae337 431 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 8 429 7.8E-171 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFE_1889 990e709c697326a0e29463441e6ae337 431 Pfam PF00709 Adenylosuccinate synthetase 7 425 5.7E-175 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFE_1889 990e709c697326a0e29463441e6ae337 431 SUPERFAMILY SSF52540 5 429 2.76E-171 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1889 990e709c697326a0e29463441e6ae337 431 SMART SM00788 6 426 5.5E-289 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFE_1889 990e709c697326a0e29463441e6ae337 431 Gene3D G3DSA:1.10.300.10 104 203 1.1E-95 T 12-10-2018 AFE_1889 990e709c697326a0e29463441e6ae337 431 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 135 146 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 SUPERFAMILY SSF52518 398 610 7.65E-21 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 Gene3D G3DSA:3.40.50.970 407 627 3.5E-97 T 12-10-2018 AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 Pfam PF09363 XFP C-terminal domain 608 809 5.3E-85 T 12-10-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 Gene3D G3DSA:3.40.50.970 15 406 7.4E-168 T 12-10-2018 AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 Pfam PF09364 XFP N-terminal domain 31 405 1.2E-182 T 12-10-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 SUPERFAMILY SSF52518 23 390 2.75E-75 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 420 597 4.4E-82 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 ProSitePatterns PS60002 Phosphoketolase signature 1. 165 171 - T 12-10-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 Gene3D G3DSA:3.40.50.920 628 814 6.3E-70 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 ProSitePatterns PS60003 Phosphoketolase signature 2. 178 196 - T 12-10-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 Hamap MF_01403 Probable phosphoketolase. 26 811 39.126 T 12-10-2018 IPR023962 Probable phosphoketolase AFE_2053 47fedfe985b7c593a17aa31fe2ddf888 815 PIRSF PIRSF017245 4 811 0.0 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 AFE_0993 40e5708a5915be9dce82b178d318ea86 252 Pfam PF12706 Beta-lactamase superfamily domain 47 224 8.7E-41 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_0993 40e5708a5915be9dce82b178d318ea86 252 SUPERFAMILY SSF56281 1 252 2.71E-51 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_0993 40e5708a5915be9dce82b178d318ea86 252 SMART SM00849 34 201 5.8E-7 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_0993 40e5708a5915be9dce82b178d318ea86 252 Gene3D G3DSA:3.60.15.10 1 252 3.4E-78 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_0406 1a0ad45765aea4386de8ee91b859ceb6 388 Gene3D G3DSA:3.40.640.10 46 293 1.4E-138 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_0406 1a0ad45765aea4386de8ee91b859ceb6 388 PIRSF PIRSF000521 159 387 2.3E-37 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFE_0406 1a0ad45765aea4386de8ee91b859ceb6 388 PIRSF PIRSF000521 4 146 8.9E-13 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFE_0406 1a0ad45765aea4386de8ee91b859ceb6 388 Gene3D G3DSA:3.90.1150.10 11 376 1.4E-138 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0406 1a0ad45765aea4386de8ee91b859ceb6 388 SUPERFAMILY SSF53383 4 384 4.27E-123 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_0406 1a0ad45765aea4386de8ee91b859ceb6 388 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 3 384 1.5E-137 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AFE_0406 1a0ad45765aea4386de8ee91b859ceb6 388 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 2 387 69.103 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AFE_0406 1a0ad45765aea4386de8ee91b859ceb6 388 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 210 248 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFE_0406 1a0ad45765aea4386de8ee91b859ceb6 388 Pfam PF00202 Aminotransferase class-III 10 381 5.4E-108 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFE_1089 d2a9fa43b32044934a1ef91344677eed 866 SUPERFAMILY SSF52540 441 749 1.82E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1089 d2a9fa43b32044934a1ef91344677eed 866 Gene3D G3DSA:1.10.8.730 510 626 2.5E-31 T 12-10-2018 AFE_1089 d2a9fa43b32044934a1ef91344677eed 866 TIGRFAM TIGR02746 TraC-F-type: type-IV secretion system protein TraC 23 818 4.7E-271 T 12-10-2018 IPR014117 Type-IV secretion system protein TraC AFE_1089 d2a9fa43b32044934a1ef91344677eed 866 Gene3D G3DSA:3.40.50.300 447 738 2.5E-31 T 12-10-2018 AFE_1089 d2a9fa43b32044934a1ef91344677eed 866 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 19 250 1.5E-36 T 12-10-2018 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase AFE_3116 a30703ef63d7ae6c19f056f28f21f75e 128 Pfam PF13686 DsrE/DsrF/DrsH-like family 59 125 5.5E-9 T 12-10-2018 IPR032836 DsrE2-like family AFE_3116 a30703ef63d7ae6c19f056f28f21f75e 128 SUPERFAMILY SSF75169 15 116 9.62E-11 T 12-10-2018 IPR027396 DsrEFH-like AFE_3116 a30703ef63d7ae6c19f056f28f21f75e 128 Gene3D G3DSA:3.40.1260.10 1 128 5.7E-22 T 12-10-2018 IPR027396 DsrEFH-like AFE_2599 a30703ef63d7ae6c19f056f28f21f75e 128 Pfam PF13686 DsrE/DsrF/DrsH-like family 59 125 5.5E-9 T 12-10-2018 IPR032836 DsrE2-like family AFE_2599 a30703ef63d7ae6c19f056f28f21f75e 128 SUPERFAMILY SSF75169 15 116 9.62E-11 T 12-10-2018 IPR027396 DsrEFH-like AFE_2599 a30703ef63d7ae6c19f056f28f21f75e 128 Gene3D G3DSA:3.40.1260.10 1 128 5.7E-22 T 12-10-2018 IPR027396 DsrEFH-like AFE_0119 e25778f29eddd9d4756f29b6caa3694c 220 SUPERFAMILY SSF51206 6 145 2.23E-26 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFE_0119 e25778f29eddd9d4756f29b6caa3694c 220 SMART SM00419 161 208 4.6E-7 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_0119 e25778f29eddd9d4756f29b6caa3694c 220 Gene3D G3DSA:1.10.10.10 144 218 3.1E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0119 e25778f29eddd9d4756f29b6caa3694c 220 SUPERFAMILY SSF46785 149 217 4.92E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0119 e25778f29eddd9d4756f29b6caa3694c 220 Pfam PF13545 Crp-like helix-turn-helix domain 151 215 1.2E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_0119 e25778f29eddd9d4756f29b6caa3694c 220 Pfam PF00027 Cyclic nucleotide-binding domain 31 117 2.1E-11 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFE_0119 e25778f29eddd9d4756f29b6caa3694c 220 Gene3D G3DSA:2.60.120.10 2 143 2.2E-42 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_2916 37112ea4cb4f2e02a8698a30cad3aaf1 434 Pfam PF00909 Ammonium Transporter Family 12 420 6.8E-87 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AFE_2916 37112ea4cb4f2e02a8698a30cad3aaf1 434 PRINTS PR00342 Rhesus blood group protein signature 208 226 3.0E-10 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFE_2916 37112ea4cb4f2e02a8698a30cad3aaf1 434 PRINTS PR00342 Rhesus blood group protein signature 113 129 3.0E-10 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFE_2916 37112ea4cb4f2e02a8698a30cad3aaf1 434 PRINTS PR00342 Rhesus blood group protein signature 331 347 3.0E-10 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFE_2916 37112ea4cb4f2e02a8698a30cad3aaf1 434 PRINTS PR00342 Rhesus blood group protein signature 239 261 3.0E-10 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFE_2916 37112ea4cb4f2e02a8698a30cad3aaf1 434 PRINTS PR00342 Rhesus blood group protein signature 294 312 3.0E-10 T 12-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AFE_2916 37112ea4cb4f2e02a8698a30cad3aaf1 434 TIGRFAM TIGR00836 amt: ammonium transporter 10 420 1.5E-115 T 12-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AFE_2916 37112ea4cb4f2e02a8698a30cad3aaf1 434 SUPERFAMILY SSF111352 5 402 7.06E-100 T 12-10-2018 AFE_2916 37112ea4cb4f2e02a8698a30cad3aaf1 434 ProSitePatterns PS01219 Ammonium transporters signature. 169 194 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AFE_2916 37112ea4cb4f2e02a8698a30cad3aaf1 434 Gene3D G3DSA:1.10.3430.10 1 432 2.2E-126 T 12-10-2018 IPR029020 Ammonium/urea transporter AFE_0617 42c4d1d5ac68554269ec341a2cb36cd4 609 Gene3D G3DSA:1.20.1560.10 15 343 8.4E-84 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_0617 42c4d1d5ac68554269ec341a2cb36cd4 609 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_0617 42c4d1d5ac68554269ec341a2cb36cd4 609 Gene3D G3DSA:3.40.50.300 354 607 4.2E-89 T 12-10-2018 AFE_0617 42c4d1d5ac68554269ec341a2cb36cd4 609 SUPERFAMILY SSF52540 350 595 9.27E-88 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0617 42c4d1d5ac68554269ec341a2cb36cd4 609 SUPERFAMILY SSF90123 17 349 1.29E-73 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_0617 42c4d1d5ac68554269ec341a2cb36cd4 609 Pfam PF00005 ABC transporter 377 526 1.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0617 42c4d1d5ac68554269ec341a2cb36cd4 609 Pfam PF00664 ABC transporter transmembrane region 40 312 6.9E-46 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFE_0617 42c4d1d5ac68554269ec341a2cb36cd4 609 SMART SM00382 386 572 2.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0156 e609821436daea0e0ff17097387dfe5f 316 Pfam PF17284 Spermidine synthase tetramerisation domain 43 95 2.8E-18 T 12-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFE_0156 e609821436daea0e0ff17097387dfe5f 316 SUPERFAMILY SSF53335 39 314 8.31E-74 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0156 e609821436daea0e0ff17097387dfe5f 316 Gene3D G3DSA:3.40.50.150 98 315 2.9E-61 T 12-10-2018 AFE_0156 e609821436daea0e0ff17097387dfe5f 316 TIGRFAM TIGR00417 speE: spermidine synthase 44 313 2.1E-81 T 12-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFE_0156 e609821436daea0e0ff17097387dfe5f 316 Gene3D G3DSA:2.30.140.10 41 93 3.8E-21 T 12-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFE_0156 e609821436daea0e0ff17097387dfe5f 316 Pfam PF01564 Spermine/spermidine synthase domain 100 278 1.4E-47 T 12-10-2018 AFE_0156 e609821436daea0e0ff17097387dfe5f 316 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 43 305 35.361 T 12-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFE_0156 e609821436daea0e0ff17097387dfe5f 316 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 120 133 - T 12-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFE_1656 7c060abe664a1bce2072174230c4070c 342 Gene3D G3DSA:3.10.20.30 1 97 1.6E-21 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_1656 7c060abe664a1bce2072174230c4070c 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 241 250 5.5E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_1656 7c060abe664a1bce2072174230c4070c 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 216 235 5.5E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_1656 7c060abe664a1bce2072174230c4070c 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 200 209 5.5E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_1656 7c060abe664a1bce2072174230c4070c 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 307 315 5.5E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_1656 7c060abe664a1bce2072174230c4070c 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 140 152 5.5E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_1656 7c060abe664a1bce2072174230c4070c 342 PRINTS PR00410 Phenol hydroxylase reductase family signature 157 164 5.5E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 AFE_1656 7c060abe664a1bce2072174230c4070c 342 SUPERFAMILY SSF54292 3 97 7.6E-20 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFE_1656 7c060abe664a1bce2072174230c4070c 342 Pfam PF00970 Oxidoreductase FAD-binding domain 110 205 4.7E-15 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 AFE_1656 7c060abe664a1bce2072174230c4070c 342 Gene3D G3DSA:2.40.30.10 99 203 6.3E-24 T 12-10-2018 AFE_1656 7c060abe664a1bce2072174230c4070c 342 SUPERFAMILY SSF52343 196 337 2.23E-31 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFE_1656 7c060abe664a1bce2072174230c4070c 342 SUPERFAMILY SSF63380 107 210 3.58E-22 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFE_1656 7c060abe664a1bce2072174230c4070c 342 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFE_1656 7c060abe664a1bce2072174230c4070c 342 Gene3D G3DSA:3.40.50.80 205 342 9.0E-31 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFE_1656 7c060abe664a1bce2072174230c4070c 342 Pfam PF00175 Oxidoreductase NAD-binding domain 217 320 3.4E-17 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFE_1656 7c060abe664a1bce2072174230c4070c 342 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 85 9.5E-12 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 223 405 7.3E-71 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 Gene3D G3DSA:2.30.210.10 579 590 2.2E-253 T 12-10-2018 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 Pfam PF09334 tRNA synthetases class I (M) 41 176 1.4E-20 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 Gene3D G3DSA:3.90.740.10 230 418 2.2E-253 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 SUPERFAMILY SSF50677 228 418 8.16E-55 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 Pfam PF08264 Anticodon-binding domain of tRNA 664 784 6.3E-17 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 421 621 7.0E-21 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 PRINTS PR00985 Leucyl-tRNA synthetase signature 154 170 7.4E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 PRINTS PR00985 Leucyl-tRNA synthetase signature 217 236 7.4E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 PRINTS PR00985 Leucyl-tRNA synthetase signature 527 549 7.4E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 PRINTS PR00985 Leucyl-tRNA synthetase signature 186 199 7.4E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 PRINTS PR00985 Leucyl-tRNA synthetase signature 128 145 7.4E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 PRINTS PR00985 Leucyl-tRNA synthetase signature 490 508 7.4E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 PRINTS PR00985 Leucyl-tRNA synthetase signature 564 574 7.4E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 SUPERFAMILY SSF52374 5 631 1.93E-143 T 12-10-2018 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 6 820 0.0 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 Gene3D G3DSA:3.40.50.620 35 578 2.2E-253 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 Gene3D G3DSA:3.10.20.590 760 821 2.1E-22 T 12-10-2018 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 5 820 22.866 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 SUPERFAMILY SSF47323 626 819 7.48E-35 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0459 299bf237eb370a70fddb7e1db5f963e2 821 Gene3D G3DSA:1.10.730.10 600 757 8.2E-45 T 12-10-2018 AFE_0188 35276e92f8cc9c6e3aad070a3223511e 250 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 248 26.449 T 12-10-2018 IPR009777 Cell division protein ZapD AFE_0188 35276e92f8cc9c6e3aad070a3223511e 250 Gene3D G3DSA:1.10.3900.10 10 175 6.8E-56 T 12-10-2018 AFE_0188 35276e92f8cc9c6e3aad070a3223511e 250 Gene3D G3DSA:2.60.440.10 3 245 6.8E-56 T 12-10-2018 IPR027462 Z ring-associated protein D, C-terminal AFE_0188 35276e92f8cc9c6e3aad070a3223511e 250 Pfam PF07072 Cell division protein 16 223 4.5E-44 T 12-10-2018 IPR009777 Cell division protein ZapD AFE_0188 35276e92f8cc9c6e3aad070a3223511e 250 SUPERFAMILY SSF160950 1 246 1.83E-58 T 12-10-2018 IPR036268 ZapD domain superfamily AFE_0313 3f01910b9442769f3807740f7057d36c 116 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 60 88 - T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFE_0313 3f01910b9442769f3807740f7057d36c 116 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 60 112 3.3E-13 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 AFE_0313 3f01910b9442769f3807740f7057d36c 116 Gene3D G3DSA:1.20.5.1030 55 111 2.3E-15 T 12-10-2018 IPR038379 SecE superfamily AFE_0313 3f01910b9442769f3807740f7057d36c 116 PRINTS PR01650 Bacterial translocase SecE signature 33 54 2.1E-15 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 AFE_0313 3f01910b9442769f3807740f7057d36c 116 PRINTS PR01650 Bacterial translocase SecE signature 78 98 2.1E-15 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 AFE_0313 3f01910b9442769f3807740f7057d36c 116 PRINTS PR01650 Bacterial translocase SecE signature 98 114 2.1E-15 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 AFE_0313 3f01910b9442769f3807740f7057d36c 116 PRINTS PR01650 Bacterial translocase SecE signature 54 74 2.1E-15 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 AFE_0313 3f01910b9442769f3807740f7057d36c 116 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 60 111 4.1E-15 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFE_0313 3f01910b9442769f3807740f7057d36c 116 Hamap MF_00422 Protein translocase subunit SecE [secE]. 55 110 11.04 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFE_0351 13f51870a4006d10670dbeb3bba820bb 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.447 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0351 13f51870a4006d10670dbeb3bba820bb 118 Gene3D G3DSA:4.10.910.10 72 118 8.2E-26 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0351 13f51870a4006d10670dbeb3bba820bb 118 Gene3D G3DSA:1.10.8.50 1 71 7.4E-29 T 12-10-2018 AFE_0351 13f51870a4006d10670dbeb3bba820bb 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.6E-54 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0351 13f51870a4006d10670dbeb3bba820bb 118 SUPERFAMILY SSF46946 2 113 1.31E-46 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFE_0351 13f51870a4006d10670dbeb3bba820bb 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 12-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0351 13f51870a4006d10670dbeb3bba820bb 118 PIRSF PIRSF002134 1 118 7.1E-44 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0351 13f51870a4006d10670dbeb3bba820bb 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.2E-33 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 Pfam PF01568 Molydopterin dinucleotide binding domain 814 901 4.7E-14 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 SUPERFAMILY SSF53706 37 620 1.1E-116 T 12-10-2018 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 Gene3D G3DSA:3.40.50.740 111 173 9.1E-31 T 12-10-2018 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 SUPERFAMILY SSF50692 726 909 5.88E-17 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 Gene3D G3DSA:3.40.228.10 349 473 1.0E-20 T 12-10-2018 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 Gene3D G3DSA:2.40.40.20 769 909 8.6E-29 T 12-10-2018 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 Gene3D G3DSA:3.40.228.10 174 287 9.1E-31 T 12-10-2018 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 39 95 5.0E-10 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 Gene3D G3DSA:2.20.25.90 35 100 5.7E-14 T 12-10-2018 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 Gene3D G3DSA:3.40.50.740 492 669 1.3E-14 T 12-10-2018 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 SMART SM00926 37 95 7.5E-12 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2177 d2b3a914bbaea50cee673bf0689d6bac 909 Pfam PF00384 Molybdopterin oxidoreductase 98 619 2.7E-39 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_0659 8d4219e98779aca09c7a9c5c98c25fde 68 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 30.263 T 12-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0659 8d4219e98779aca09c7a9c5c98c25fde 68 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 66 1.7E-33 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0659 8d4219e98779aca09c7a9c5c98c25fde 68 Gene3D G3DSA:2.30.170.50 1 68 3.8E-33 T 12-10-2018 AFE_0659 8d4219e98779aca09c7a9c5c98c25fde 68 PRINTS PR01249 Ribosomal protein L31 signature 2 19 4.8E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0659 8d4219e98779aca09c7a9c5c98c25fde 68 PRINTS PR01249 Ribosomal protein L31 signature 31 46 4.8E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0659 8d4219e98779aca09c7a9c5c98c25fde 68 PRINTS PR01249 Ribosomal protein L31 signature 46 64 4.8E-22 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0659 8d4219e98779aca09c7a9c5c98c25fde 68 Pfam PF01197 Ribosomal protein L31 1 65 1.4E-32 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0659 8d4219e98779aca09c7a9c5c98c25fde 68 SUPERFAMILY SSF143800 1 65 2.59E-27 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2926 6177ca13b4d4bf37ab4c69e97896c53b 125 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 123 18.295 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFE_2926 6177ca13b4d4bf37ab4c69e97896c53b 125 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 118 1.2E-22 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFE_2926 6177ca13b4d4bf37ab4c69e97896c53b 125 TIGRFAM TIGR00494 crcB: protein CrcB 8 121 8.9E-24 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 207 272 8.7E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 Pfam PF13188 PAS domain 102 155 1.8E-4 T 12-10-2018 IPR000014 PAS domain AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 Gene3D G3DSA:3.30.565.10 280 433 1.5E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 SUPERFAMILY SSF47384 191 272 1.16E-19 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 409 2.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 2.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 428 2.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 384 2.1E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 SMART SM00388 206 273 5.2E-18 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 SUPERFAMILY SSF55874 262 433 2.75E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 429 3.3E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 96 427 1.0E-120 T 12-10-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 SUPERFAMILY SSF55785 89 198 1.42E-7 T 12-10-2018 IPR035965 PAS domain superfamily AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 Pfam PF11808 Domain of unknown function (DUF3329) 13 91 2.5E-6 T 12-10-2018 IPR021766 Phosphate regulon sensor protein PhoR GO:0000155|GO:0000160|GO:0004721 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 SMART SM00387 319 431 7.4E-36 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 Gene3D G3DSA:1.10.287.130 203 273 1.8E-21 T 12-10-2018 AFE_1435 a1cd4ee567b96fb25e605b80b653b31d 442 Gene3D G3DSA:3.30.450.20 88 202 4.4E-7 T 12-10-2018 AFE_0527 66aae933f3708b0a1f1afb6ba8e45005 828 Gene3D G3DSA:3.40.50.2000 480 806 0.0 T 12-10-2018 AFE_0527 66aae933f3708b0a1f1afb6ba8e45005 828 PIRSF PIRSF000460 15 827 3.9E-222 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFE_0527 66aae933f3708b0a1f1afb6ba8e45005 828 Pfam PF00343 Carbohydrate phosphorylase 113 821 0.0 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFE_0527 66aae933f3708b0a1f1afb6ba8e45005 828 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 666 678 - T 12-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFE_0527 66aae933f3708b0a1f1afb6ba8e45005 828 Gene3D G3DSA:3.40.50.2000 37 823 0.0 T 12-10-2018 AFE_0527 66aae933f3708b0a1f1afb6ba8e45005 828 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 34 821 0.0 T 12-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFE_0527 66aae933f3708b0a1f1afb6ba8e45005 828 SUPERFAMILY SSF53756 17 824 0.0 T 12-10-2018 AFE_2663 95762a21850528c76670eac1ea728182 276 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 6 268 1.4E-83 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_2663 95762a21850528c76670eac1ea728182 276 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 5 268 30.747 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_2663 95762a21850528c76670eac1ea728182 276 Gene3D G3DSA:3.40.50.720 7 267 5.6E-93 T 12-10-2018 AFE_2663 95762a21850528c76670eac1ea728182 276 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 153 170 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_2663 95762a21850528c76670eac1ea728182 276 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 131 267 2.3E-39 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_2663 95762a21850528c76670eac1ea728182 276 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 128 3.7E-33 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_2663 95762a21850528c76670eac1ea728182 276 SUPERFAMILY SSF51735 4 270 1.87E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2663 95762a21850528c76670eac1ea728182 276 Gene3D G3DSA:3.30.360.10 130 237 5.6E-93 T 12-10-2018 AFE_2663 95762a21850528c76670eac1ea728182 276 SUPERFAMILY SSF55347 130 239 1.11E-31 T 12-10-2018 AFE_2663 95762a21850528c76670eac1ea728182 276 PIRSF PIRSF000161 4 271 2.1E-78 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFE_0393 78f7ae15e01bb462112b8f6aeb51f1dc 293 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 5 211 2.3E-77 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0393 78f7ae15e01bb462112b8f6aeb51f1dc 293 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 26 173 2.7E-55 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 AFE_0393 78f7ae15e01bb462112b8f6aeb51f1dc 293 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 234 289 1.4E-16 T 12-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0393 78f7ae15e01bb462112b8f6aeb51f1dc 293 Gene3D G3DSA:3.30.2350.10 2 231 4.6E-88 T 12-10-2018 AFE_0393 78f7ae15e01bb462112b8f6aeb51f1dc 293 Gene3D G3DSA:2.30.130.10 232 292 2.2E-19 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 AFE_0393 78f7ae15e01bb462112b8f6aeb51f1dc 293 SUPERFAMILY SSF55120 5 215 6.33E-78 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0393 78f7ae15e01bb462112b8f6aeb51f1dc 293 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 4 290 18.826 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0393 78f7ae15e01bb462112b8f6aeb51f1dc 293 SUPERFAMILY SSF88697 233 291 1.34E-11 T 12-10-2018 IPR015947 PUA-like superfamily AFE_0393 78f7ae15e01bb462112b8f6aeb51f1dc 293 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 174 214 6.7E-15 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AFE_1987 acf793e8956f8a7280b0cb2e5937c8bb 257 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 13 239 2.2E-59 T 12-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 AFE_1987 acf793e8956f8a7280b0cb2e5937c8bb 257 Pfam PF00149 Calcineurin-like phosphoesterase 12 218 1.6E-9 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFE_1987 acf793e8956f8a7280b0cb2e5937c8bb 257 SUPERFAMILY SSF56300 13 236 1.52E-23 T 12-10-2018 AFE_1987 acf793e8956f8a7280b0cb2e5937c8bb 257 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 257 81.036 T 12-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 AFE_3196 8c472bb8ada076f6d5615933efffa620 609 Pfam PF15978 Tn7-like transposition protein D 205 544 6.3E-102 T 12-10-2018 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl AFE_3196 8c472bb8ada076f6d5615933efffa620 609 Pfam PF06527 TniQ 5 160 3.3E-22 T 12-10-2018 IPR009492 TniQ AFE_1921 d843e86d9f1f62f1bb72f98b06f517f1 199 Pfam PF13662 Toprim domain 81 170 4.1E-19 T 12-10-2018 IPR006171 TOPRIM domain AFE_1921 d843e86d9f1f62f1bb72f98b06f517f1 199 SUPERFAMILY SSF111304 5 197 1.7E-65 T 12-10-2018 IPR023627 Recombination protein RecR AFE_1921 d843e86d9f1f62f1bb72f98b06f517f1 199 Gene3D G3DSA:1.10.8.420 1 52 1.7E-13 T 12-10-2018 AFE_1921 d843e86d9f1f62f1bb72f98b06f517f1 199 SMART SM00493 80 165 1.1E-14 T 12-10-2018 IPR006171 TOPRIM domain AFE_1921 d843e86d9f1f62f1bb72f98b06f517f1 199 TIGRFAM TIGR00615 recR: recombination protein RecR 5 195 6.7E-69 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 AFE_1921 d843e86d9f1f62f1bb72f98b06f517f1 199 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 12-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 AFE_1921 d843e86d9f1f62f1bb72f98b06f517f1 199 Pfam PF02132 RecR protein 42 78 1.5E-12 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger AFE_1921 d843e86d9f1f62f1bb72f98b06f517f1 199 Gene3D G3DSA:3.40.1360.10 77 196 3.7E-39 T 12-10-2018 AFE_1921 d843e86d9f1f62f1bb72f98b06f517f1 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 87.892 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 AFE_1894 d542c79549a67acc684346007c3c7bc1 250 Gene3D G3DSA:3.40.980.10 3 163 1.2E-32 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFE_1894 d542c79549a67acc684346007c3c7bc1 250 Pfam PF00994 Probable molybdopterin binding domain 7 161 2.9E-18 T 12-10-2018 IPR001453 MoaB/Mog domain AFE_1894 d542c79549a67acc684346007c3c7bc1 250 SUPERFAMILY SSF53218 4 162 3.93E-22 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFE_1894 d542c79549a67acc684346007c3c7bc1 250 SMART SM00852 6 166 2.7E-20 T 12-10-2018 IPR001453 MoaB/Mog domain AFE_0939 e11587d4c92fd6226f413976b5112503 276 Pfam PF00175 Oxidoreductase NAD-binding domain 115 217 1.0E-11 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFE_0939 e11587d4c92fd6226f413976b5112503 276 Gene3D G3DSA:3.40.50.80 104 231 5.5E-19 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFE_0939 e11587d4c92fd6226f413976b5112503 276 PRINTS PR00406 Cytochrome B5 reductase signature 90 104 6.8E-9 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFE_0939 e11587d4c92fd6226f413976b5112503 276 PRINTS PR00406 Cytochrome B5 reductase signature 203 211 6.8E-9 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFE_0939 e11587d4c92fd6226f413976b5112503 276 PRINTS PR00406 Cytochrome B5 reductase signature 114 133 6.8E-9 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFE_0939 e11587d4c92fd6226f413976b5112503 276 PRINTS PR00406 Cytochrome B5 reductase signature 152 163 6.8E-9 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 AFE_0939 e11587d4c92fd6226f413976b5112503 276 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 235 267 9.2E-8 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain AFE_0939 e11587d4c92fd6226f413976b5112503 276 SUPERFAMILY SSF63380 5 103 4.84E-20 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFE_0939 e11587d4c92fd6226f413976b5112503 276 PIRSF PIRSF006816 4 272 1.6E-62 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 AFE_0939 e11587d4c92fd6226f413976b5112503 276 Gene3D G3DSA:2.40.30.10 6 101 2.9E-14 T 12-10-2018 AFE_0939 e11587d4c92fd6226f413976b5112503 276 SUPERFAMILY SSF52343 98 267 5.11E-27 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFE_0907 ed6c647ad50c9a727d4d896084a7be37 243 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 59 72 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_0907 ed6c647ad50c9a727d4d896084a7be37 243 Gene3D G3DSA:3.20.20.70 5 234 4.9E-79 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_0907 ed6c647ad50c9a727d4d896084a7be37 243 SMART SM00934 7 228 2.4E-90 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_0907 ed6c647ad50c9a727d4d896084a7be37 243 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 5 233 37.866 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_0907 ed6c647ad50c9a727d4d896084a7be37 243 SUPERFAMILY SSF51366 5 231 2.67E-69 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFE_0907 ed6c647ad50c9a727d4d896084a7be37 243 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 8 228 1.4E-55 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_0907 ed6c647ad50c9a727d4d896084a7be37 243 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 225 2.0E-46 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_2044 2d6162ce6207885cf0e4f4fc0de05b86 336 Pfam PF13437 HlyD family secretion protein 152 247 1.9E-5 T 12-10-2018 AFE_2044 2d6162ce6207885cf0e4f4fc0de05b86 336 Gene3D G3DSA:1.10.287.470 89 147 3.9E-36 T 12-10-2018 AFE_2044 2d6162ce6207885cf0e4f4fc0de05b86 336 Gene3D G3DSA:2.40.50.100 56 186 3.9E-36 T 12-10-2018 AFE_2044 2d6162ce6207885cf0e4f4fc0de05b86 336 SUPERFAMILY SSF111369 46 201 1.7E-13 T 12-10-2018 AFE_2044 2d6162ce6207885cf0e4f4fc0de05b86 336 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 32 329 1.7E-35 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_2044 2d6162ce6207885cf0e4f4fc0de05b86 336 Gene3D G3DSA:2.40.30.170 43 257 3.9E-36 T 12-10-2018 AFE_2044 2d6162ce6207885cf0e4f4fc0de05b86 336 Gene3D G3DSA:2.40.420.20 258 327 3.9E-36 T 12-10-2018 AFE_1934 466205508150902d4cdeb2eaec4c44a3 439 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 397 3.0E-132 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AFE_1934 466205508150902d4cdeb2eaec4c44a3 439 SUPERFAMILY SSF52954 330 414 3.02E-7 T 12-10-2018 AFE_1934 466205508150902d4cdeb2eaec4c44a3 439 PIRSF PIRSF001549 3 414 9.6E-101 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AFE_1934 466205508150902d4cdeb2eaec4c44a3 439 Gene3D G3DSA:3.40.50.800 328 406 1.8E-8 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily AFE_1934 466205508150902d4cdeb2eaec4c44a3 439 Gene3D G3DSA:3.30.930.10 4 320 2.1E-106 T 12-10-2018 AFE_1934 466205508150902d4cdeb2eaec4c44a3 439 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 4 416 29.28 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AFE_1934 466205508150902d4cdeb2eaec4c44a3 439 Pfam PF13393 Histidyl-tRNA synthetase 11 311 2.0E-42 T 12-10-2018 AFE_1934 466205508150902d4cdeb2eaec4c44a3 439 SUPERFAMILY SSF55681 7 314 1.63E-90 T 12-10-2018 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 Gene3D G3DSA:3.40.50.720 97 279 1.7E-118 T 12-10-2018 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 SUPERFAMILY SSF55021 455 525 7.08E-14 T 12-10-2018 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 Gene3D G3DSA:3.30.70.260 454 527 1.0E-16 T 12-10-2018 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 SUPERFAMILY SSF52283 4 125 8.32E-36 T 12-10-2018 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 Pfam PF01842 ACT domain 457 517 4.7E-9 T 12-10-2018 IPR002912 ACT domain AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 143 170 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 Gene3D G3DSA:3.40.50.720 5 303 1.7E-118 T 12-10-2018 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 SUPERFAMILY SSF51735 101 281 1.18E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 313 5.4E-37 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 4 526 1.6E-198 T 12-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 SUPERFAMILY SSF143548 322 449 1.8E-33 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 281 3.3E-65 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFE_0896 dcd24aca8f6ea913a3da40fac0b86f17 527 Gene3D G3DSA:3.30.1330.90 322 453 8.2E-35 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 9 385 6.0E-130 T 12-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 SUPERFAMILY SSF48256 5 385 9.81E-128 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 Pfam PF00285 Citrate synthase, C-terminal domain 9 368 2.5E-124 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 ProSitePatterns PS00480 Citrate synthase signature. 263 275 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 PIRSF PIRSF001369 1 386 2.3E-142 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 PRINTS PR00143 Citrate synthase signature 181 196 1.3E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 PRINTS PR00143 Citrate synthase signature 338 352 1.3E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 PRINTS PR00143 Citrate synthase signature 132 145 1.3E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 PRINTS PR00143 Citrate synthase signature 203 231 1.3E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 PRINTS PR00143 Citrate synthase signature 256 276 1.3E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 PRINTS PR00143 Citrate synthase signature 318 334 1.3E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 Gene3D G3DSA:1.10.580.10 19 359 1.5E-123 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFE_3065 a7d440b6a4e100e4274681179cc1c134 386 Gene3D G3DSA:1.10.230.10 230 335 1.5E-123 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 SUPERFAMILY SSF52518 348 537 9.06E-68 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 ProSitePatterns PS00802 Transketolase signature 2. 479 495 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 Gene3D G3DSA:3.40.50.920 552 676 8.4E-38 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 16 349 3.0E-145 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 SUPERFAMILY SSF52518 4 335 9.09E-105 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 Gene3D G3DSA:3.40.50.970 342 543 2.4E-79 T 12-10-2018 AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 Gene3D G3DSA:3.40.50.970 14 341 6.0E-115 T 12-10-2018 AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 Pfam PF02779 Transketolase, pyrimidine binding domain 366 536 1.8E-44 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 TIGRFAM TIGR00232 tktlase_bact: transketolase 19 675 1.4E-263 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 SUPERFAMILY SSF52922 547 676 1.2E-36 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 Pfam PF02780 Transketolase, C-terminal domain 563 668 6.2E-9 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFE_1843 d83a6ea8ac19d4ec79d7939d8f87e19a 676 SMART SM00861 366 537 1.9E-65 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_1427 920c6d6671811daf2da90347596844f7 404 Pfam PF13439 Glycosyltransferase Family 4 15 185 5.4E-30 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_1427 920c6d6671811daf2da90347596844f7 404 SUPERFAMILY SSF53756 2 378 7.07E-80 T 12-10-2018 AFE_1427 920c6d6671811daf2da90347596844f7 404 Pfam PF00534 Glycosyl transferases group 1 192 360 1.7E-32 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1427 920c6d6671811daf2da90347596844f7 404 Gene3D G3DSA:3.40.50.2000 1 203 1.5E-34 T 12-10-2018 AFE_1427 920c6d6671811daf2da90347596844f7 404 Gene3D G3DSA:3.40.50.2000 204 364 2.9E-36 T 12-10-2018 AFE_1815 e7d803436e523d4a6bc136672ce57b34 507 SUPERFAMILY SSF64158 77 300 1.57E-68 T 12-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_1815 e7d803436e523d4a6bc136672ce57b34 507 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 501 4.5E-181 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_1815 e7d803436e523d4a6bc136672ce57b34 507 Pfam PF01676 Metalloenzyme superfamily 5 490 3.0E-66 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 AFE_1815 e7d803436e523d4a6bc136672ce57b34 507 PIRSF PIRSF001492 1 504 6.3E-176 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_1815 e7d803436e523d4a6bc136672ce57b34 507 SUPERFAMILY SSF53649 4 501 7.72E-69 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFE_1815 e7d803436e523d4a6bc136672ce57b34 507 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 502 43.406 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_1815 e7d803436e523d4a6bc136672ce57b34 507 Gene3D G3DSA:3.40.720.10 5 501 3.3E-192 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_1815 e7d803436e523d4a6bc136672ce57b34 507 Gene3D G3DSA:3.40.1450.10 77 302 3.3E-192 T 12-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_1815 e7d803436e523d4a6bc136672ce57b34 507 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 290 2.1E-63 T 12-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0491 580b3adfafcfebc257fb7d15b75fcf89 253 Pfam PF02348 Cytidylyltransferase 5 226 2.0E-45 T 12-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 AFE_0491 580b3adfafcfebc257fb7d15b75fcf89 253 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 2 246 1.7E-75 T 12-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 AFE_0491 580b3adfafcfebc257fb7d15b75fcf89 253 Gene3D G3DSA:3.90.550.10 1 252 2.9E-78 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0491 580b3adfafcfebc257fb7d15b75fcf89 253 SUPERFAMILY SSF53448 3 251 1.03E-52 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0491 580b3adfafcfebc257fb7d15b75fcf89 253 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 253 37.381 T 12-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 AFE_2580 a31a3819ee40987f895a106e607bd931 294 Gene3D G3DSA:3.30.930.10 1 204 1.8E-109 T 12-10-2018 AFE_2580 a31a3819ee40987f895a106e607bd931 294 Gene3D G3DSA:1.20.58.180 205 286 2.1E-30 T 12-10-2018 AFE_2580 a31a3819ee40987f895a106e607bd931 294 SUPERFAMILY SSF55681 1 279 3.71E-130 T 12-10-2018 AFE_2580 a31a3819ee40987f895a106e607bd931 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 1.4E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2580 a31a3819ee40987f895a106e607bd931 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 1.4E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2580 a31a3819ee40987f895a106e607bd931 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 1.4E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2580 a31a3819ee40987f895a106e607bd931 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 1.4E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2580 a31a3819ee40987f895a106e607bd931 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 1.4E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2580 a31a3819ee40987f895a106e607bd931 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 1.4E-66 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2580 a31a3819ee40987f895a106e607bd931 294 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 279 6.2E-145 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2580 a31a3819ee40987f895a106e607bd931 294 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 58.404 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2580 a31a3819ee40987f895a106e607bd931 294 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 287 8.4E-148 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_1533 3e1862c8a503be64dd54a705c6366920 169 Gene3D G3DSA:1.25.40.10 28 169 4.5E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1533 3e1862c8a503be64dd54a705c6366920 169 SUPERFAMILY SSF48452 39 166 8.54E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 SUPERFAMILY SSF47384 217 283 6.47E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 Gene3D G3DSA:3.30.565.10 289 436 1.4E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 228 284 2.5E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 Gene3D G3DSA:1.10.287.130 170 282 2.4E-15 T 12-10-2018 AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 379 2.0E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 413 2.0E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 SMART SM00304 173 226 5.5E-5 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 SMART SM00388 227 287 1.2E-5 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 334 426 5.9E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 SUPERFAMILY SSF55874 293 438 9.17E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0106 1f6e4ce850a51b19b5860f6b6492e6c2 446 SMART SM00387 330 435 7.5E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2385 06b498d2de5119031c46ed1442ad67b3 147 Pfam PF02036 SCP-2 sterol transfer family 34 131 5.4E-15 T 12-10-2018 IPR003033 SCP2 sterol-binding domain AFE_2385 06b498d2de5119031c46ed1442ad67b3 147 Gene3D G3DSA:3.30.1050.10 20 141 1.4E-23 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFE_2385 06b498d2de5119031c46ed1442ad67b3 147 SUPERFAMILY SSF55718 16 146 2.12E-33 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFE_2167 87e8b70fabc06c4c4a3c91c1367b963f 723 Gene3D G3DSA:3.90.70.10 11 155 1.9E-38 T 12-10-2018 AFE_2167 87e8b70fabc06c4c4a3c91c1367b963f 723 Gene3D G3DSA:1.20.1560.10 160 475 7.7E-59 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_2167 87e8b70fabc06c4c4a3c91c1367b963f 723 Pfam PF00005 ABC transporter 506 655 2.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2167 87e8b70fabc06c4c4a3c91c1367b963f 723 ProSitePatterns PS00211 ABC transporters family signature. 627 641 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2167 87e8b70fabc06c4c4a3c91c1367b963f 723 SMART SM00382 515 697 3.1E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2167 87e8b70fabc06c4c4a3c91c1367b963f 723 Gene3D G3DSA:3.40.50.300 484 719 2.1E-68 T 12-10-2018 AFE_2167 87e8b70fabc06c4c4a3c91c1367b963f 723 SUPERFAMILY SSF90123 168 473 1.07E-54 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_2167 87e8b70fabc06c4c4a3c91c1367b963f 723 Pfam PF00664 ABC transporter transmembrane region 177 441 2.9E-37 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFE_2167 87e8b70fabc06c4c4a3c91c1367b963f 723 SUPERFAMILY SSF52540 484 701 7.5E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2167 87e8b70fabc06c4c4a3c91c1367b963f 723 Pfam PF03412 Peptidase C39 family 19 146 1.1E-34 T 12-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 AFE_3011 ec7a2794d41c989d9fd39ac00a8d1ed5 441 Pfam PF00155 Aminotransferase class I and II 91 432 8.4E-55 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFE_3011 ec7a2794d41c989d9fd39ac00a8d1ed5 441 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 289 298 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 AFE_3011 ec7a2794d41c989d9fd39ac00a8d1ed5 441 Gene3D G3DSA:3.40.640.10 106 342 8.4E-138 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_3011 ec7a2794d41c989d9fd39ac00a8d1ed5 441 Gene3D G3DSA:3.90.1150.10 87 435 8.4E-138 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_3011 ec7a2794d41c989d9fd39ac00a8d1ed5 441 SUPERFAMILY SSF53383 67 438 4.71E-107 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 PIRSF PIRSF000724 1 400 8.1E-143 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 394 40.468 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 Pfam PF00162 Phosphoglycerate kinase 7 384 1.3E-148 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 Gene3D G3DSA:3.40.50.1260 171 384 1.3E-151 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 Gene3D G3DSA:3.40.50.1260 8 392 1.3E-151 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 SUPERFAMILY SSF53748 3 394 1.3E-148 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 1.4E-83 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 PRINTS PR00477 Phosphoglycerate kinase family signature 347 358 1.4E-83 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 PRINTS PR00477 Phosphoglycerate kinase family signature 169 191 1.4E-83 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 PRINTS PR00477 Phosphoglycerate kinase family signature 370 387 1.4E-83 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 1.4E-83 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 PRINTS PR00477 Phosphoglycerate kinase family signature 138 160 1.4E-83 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 PRINTS PR00477 Phosphoglycerate kinase family signature 314 339 1.4E-83 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.4E-83 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3250 3236cdfc8016faae3f0ffe5e91b2bbb8 401 PRINTS PR00477 Phosphoglycerate kinase family signature 192 211 1.4E-83 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3061 fdefad541336c1724a94029cf8f93559 143 SMART SM00732 6 106 2.1E-25 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 AFE_3061 fdefad541336c1724a94029cf8f93559 143 Pfam PF03652 Holliday junction resolvase 8 135 4.5E-36 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFE_3061 fdefad541336c1724a94029cf8f93559 143 Gene3D G3DSA:3.30.420.140 4 139 5.6E-37 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 AFE_3061 fdefad541336c1724a94029cf8f93559 143 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 9 136 1.1E-32 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFE_3061 fdefad541336c1724a94029cf8f93559 143 SUPERFAMILY SSF53098 7 136 1.97E-34 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_3061 fdefad541336c1724a94029cf8f93559 143 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 6 141 20.697 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFE_1512 fe5ccb3d9d72a62d684d90f68423156c 102 Gene3D G3DSA:3.30.70.20 53 91 1.4E-5 T 12-10-2018 AFE_1512 fe5ccb3d9d72a62d684d90f68423156c 102 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_1512 fe5ccb3d9d72a62d684d90f68423156c 102 SUPERFAMILY SSF54862 8 93 9.21E-18 T 12-10-2018 AFE_1512 fe5ccb3d9d72a62d684d90f68423156c 102 Pfam PF14697 4Fe-4S dicluster domain 21 88 6.7E-11 T 12-10-2018 AFE_1512 fe5ccb3d9d72a62d684d90f68423156c 102 Gene3D G3DSA:3.30.70.20 7 52 1.9E-5 T 12-10-2018 AFE_1512 fe5ccb3d9d72a62d684d90f68423156c 102 TIGRFAM TIGR02936 fdxN_nitrog: ferredoxin III, nif-specific 6 92 8.3E-43 T 12-10-2018 IPR014283 Ferredoxin III 4[4Fe-4S], nif-specific AFE_1512 fe5ccb3d9d72a62d684d90f68423156c 102 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 27 38 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_2773 99537806685e1a09619d9d169835947e 293 Pfam PF00043 Glutathione S-transferase, C-terminal domain 184 252 4.5E-11 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal AFE_2773 99537806685e1a09619d9d169835947e 293 Pfam PF02798 Glutathione S-transferase, N-terminal domain 47 129 1.5E-7 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFE_2773 99537806685e1a09619d9d169835947e 293 Gene3D G3DSA:1.20.1050.10 135 251 1.2E-107 T 12-10-2018 AFE_2773 99537806685e1a09619d9d169835947e 293 Gene3D G3DSA:3.40.30.10 21 258 1.2E-107 T 12-10-2018 AFE_2773 99537806685e1a09619d9d169835947e 293 SUPERFAMILY SSF47616 119 261 1.0E-34 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily AFE_2773 99537806685e1a09619d9d169835947e 293 SUPERFAMILY SSF52833 40 132 8.59E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_2144 1e1a79eb94fc8f8c6e463cdef5a604fa 636 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 230 1.7E-41 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFE_2144 1e1a79eb94fc8f8c6e463cdef5a604fa 636 Gene3D G3DSA:3.90.1310.10 60 241 7.4E-41 T 12-10-2018 AFE_2144 1e1a79eb94fc8f8c6e463cdef5a604fa 636 Gene3D G3DSA:3.30.1390.30 81 156 7.4E-41 T 12-10-2018 AFE_2144 1e1a79eb94fc8f8c6e463cdef5a604fa 636 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 16 597 5.3E-188 T 12-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_2144 1e1a79eb94fc8f8c6e463cdef5a604fa 636 Gene3D G3DSA:3.40.710.10 246 601 8.8E-90 T 12-10-2018 AFE_2144 1e1a79eb94fc8f8c6e463cdef5a604fa 636 Pfam PF00905 Penicillin binding protein transpeptidase domain 265 590 4.0E-69 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFE_2144 1e1a79eb94fc8f8c6e463cdef5a604fa 636 SUPERFAMILY SSF56601 250 600 2.11E-93 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_2144 1e1a79eb94fc8f8c6e463cdef5a604fa 636 SUPERFAMILY SSF56519 52 243 9.55E-45 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 Gene3D G3DSA:3.30.300.10 103 378 1.2E-176 T 12-10-2018 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 Pfam PF02772 S-adenosylmethionine synthetase, central domain 117 234 1.6E-45 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 Gene3D G3DSA:3.30.300.10 6 236 1.2E-176 T 12-10-2018 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 SUPERFAMILY SSF55973 4 111 4.71E-46 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 236 375 2.5E-67 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 262 270 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 SUPERFAMILY SSF55973 236 387 2.67E-68 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 119 129 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 Gene3D G3DSA:3.30.300.10 12 273 1.2E-176 T 12-10-2018 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 386 57.329 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 PIRSF PIRSF000497 1 387 1.4E-170 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 1.4E-41 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 385 2.8E-182 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0532 78dffe4d2355c97b4a7cdf22932590cf 389 SUPERFAMILY SSF55973 117 235 2.0E-51 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFE_0033 31239eff5560bca83e5c282e37dbdb30 71 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 9 71 4.3E-26 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFE_0033 31239eff5560bca83e5c282e37dbdb30 71 SMART SM01234 3 70 7.5E-43 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFE_0033 31239eff5560bca83e5c282e37dbdb30 71 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 3 71 24.11 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFE_0033 31239eff5560bca83e5c282e37dbdb30 71 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 18 70 3.0E-17 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFE_0033 31239eff5560bca83e5c282e37dbdb30 71 Pfam PF01809 Haemolytic domain 5 70 5.4E-30 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFE_2279 2c85c09f6004d9563f6a3701f7c44e2e 180 Gene3D G3DSA:3.40.50.11310 2 179 2.1E-49 T 12-10-2018 IPR038058 PhnH-like superfamily AFE_2279 2c85c09f6004d9563f6a3701f7c44e2e 180 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 3 176 2.1E-55 T 12-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 AFE_2279 2c85c09f6004d9563f6a3701f7c44e2e 180 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 3 178 3.1E-49 T 12-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 AFE_2279 2c85c09f6004d9563f6a3701f7c44e2e 180 SUPERFAMILY SSF159709 5 178 7.72E-52 T 12-10-2018 IPR038058 PhnH-like superfamily AFE_2279 2c85c09f6004d9563f6a3701f7c44e2e 180 PIRSF PIRSF020680 1 180 4.1E-47 T 12-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 AFE_0257 84e0ba21497b593da88c0fbbb00e49c3 337 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 41 268 7.3E-20 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_0257 84e0ba21497b593da88c0fbbb00e49c3 337 Gene3D G3DSA:2.40.30.170 204 326 4.3E-38 T 12-10-2018 AFE_0257 84e0ba21497b593da88c0fbbb00e49c3 337 Gene3D G3DSA:1.10.287.470 100 168 3.5E-5 T 12-10-2018 AFE_0257 84e0ba21497b593da88c0fbbb00e49c3 337 Gene3D G3DSA:1.10.287.470 76 99 5.5E-11 T 12-10-2018 AFE_0257 84e0ba21497b593da88c0fbbb00e49c3 337 SUPERFAMILY SSF111369 41 117 7.32E-11 T 12-10-2018 AFE_0257 84e0ba21497b593da88c0fbbb00e49c3 337 Gene3D G3DSA:2.40.50.100 42 75 5.5E-11 T 12-10-2018 AFE_0257 84e0ba21497b593da88c0fbbb00e49c3 337 SUPERFAMILY SSF111369 106 266 6.67E-7 T 12-10-2018 AFE_0416 be49d3e1937e6799e06b3551c3fa68b4 178 SUPERFAMILY SSF54523 16 115 2.51E-16 T 12-10-2018 AFE_0416 be49d3e1937e6799e06b3551c3fa68b4 178 Gene3D G3DSA:3.30.700.10 16 166 1.1E-19 T 12-10-2018 AFE_0416 be49d3e1937e6799e06b3551c3fa68b4 178 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 35 9.0E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFE_0416 be49d3e1937e6799e06b3551c3fa68b4 178 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 14 36 6.2E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFE_0416 be49d3e1937e6799e06b3551c3fa68b4 178 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFE_1404 7512da34c8e10fb0dd5679d2f7291ed0 129 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 97 2.8E-15 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFE_1404 7512da34c8e10fb0dd5679d2f7291ed0 129 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 127 23.022 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFE_1404 7512da34c8e10fb0dd5679d2f7291ed0 129 Gene3D G3DSA:3.90.470.20 1 127 1.2E-31 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFE_1404 7512da34c8e10fb0dd5679d2f7291ed0 129 SUPERFAMILY SSF56214 1 126 2.75E-24 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFE_1404 7512da34c8e10fb0dd5679d2f7291ed0 129 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 87 3.0E-7 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFE_1404 7512da34c8e10fb0dd5679d2f7291ed0 129 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 127 2.2E-25 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFE_1404 7512da34c8e10fb0dd5679d2f7291ed0 129 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 127 1.4E-20 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFE_0779 e6f4032c3d6186ddd9df0e8b67505aca 363 Gene3D G3DSA:3.30.1330.160 247 362 1.6E-39 T 12-10-2018 AFE_0779 e6f4032c3d6186ddd9df0e8b67505aca 363 Gene3D G3DSA:3.30.1330.180 107 246 1.9E-43 T 12-10-2018 AFE_0779 e6f4032c3d6186ddd9df0e8b67505aca 363 TIGRFAM TIGR02714 amido_AtzD_TrzD: ring-opening amidohydrolases 5 359 1.2E-101 T 12-10-2018 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 AFE_0779 e6f4032c3d6186ddd9df0e8b67505aca 363 Gene3D G3DSA:3.30.1330.170 1 104 2.6E-33 T 12-10-2018 AFE_0779 e6f4032c3d6186ddd9df0e8b67505aca 363 Hamap MF_01989 Cyanuric acid amidohydrolase. 1 362 32.75 T 12-10-2018 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 AFE_0779 e6f4032c3d6186ddd9df0e8b67505aca 363 Pfam PF09663 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) 5 359 2.4E-129 T 12-10-2018 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 AFE_2130 c08d216179b662ac465608d35dce9252 76 SUPERFAMILY SSF89447 4 63 1.99E-6 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFE_2130 c08d216179b662ac465608d35dce9252 76 Gene3D G3DSA:2.10.260.10 1 76 1.5E-37 T 12-10-2018 AFE_2130 c08d216179b662ac465608d35dce9252 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 33 2.7E-6 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 Pfam PF02954 Bacterial regulatory protein, Fis family 424 462 3.2E-14 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 SUPERFAMILY SSF52540 135 379 2.2E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2901 00f94086be02abf9538c90d32ac7954f 468 Gene3D G3DSA:3.40.50.300 126 307 2.0E-64 T 12-10-2018 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 SUPERFAMILY SSF52172 2 181 1.07E-41 T 12-10-2018 IPR011006 CheY-like superfamily AFE_2901 00f94086be02abf9538c90d32ac7954f 468 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 4 462 3.4E-238 T 12-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 Gene3D G3DSA:1.10.10.60 380 465 3.6E-21 T 12-10-2018 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 Pfam PF00158 Sigma-54 interaction domain 136 303 2.7E-69 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 349 358 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_2901 00f94086be02abf9538c90d32ac7954f 468 Gene3D G3DSA:1.10.8.60 308 379 1.3E-20 T 12-10-2018 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 Gene3D G3DSA:3.40.50.2300 1 120 6.1E-37 T 12-10-2018 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 160 173 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 Pfam PF00072 Response regulator receiver domain 4 113 1.2E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 SMART SM00382 156 299 1.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2901 00f94086be02abf9538c90d32ac7954f 468 SUPERFAMILY SSF46689 376 464 1.66E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 428 445 1.3E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 445 465 1.3E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_2901 00f94086be02abf9538c90d32ac7954f 468 SMART SM00448 2 113 2.4E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_1820 dd9cb9c9f9b1b8e1dd7222f4e173125a 274 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 5 70 1.4E-25 T 12-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 AFE_1820 dd9cb9c9f9b1b8e1dd7222f4e173125a 274 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 176 210 3.7E-12 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_1820 dd9cb9c9f9b1b8e1dd7222f4e173125a 274 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 135 163 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFE_1820 dd9cb9c9f9b1b8e1dd7222f4e173125a 274 Gene3D G3DSA:2.160.10.10 88 258 6.1E-57 T 12-10-2018 AFE_1820 dd9cb9c9f9b1b8e1dd7222f4e173125a 274 Gene3D G3DSA:1.10.166.10 2 71 2.4E-30 T 12-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 AFE_1820 dd9cb9c9f9b1b8e1dd7222f4e173125a 274 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 273 56.884 T 12-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 AFE_1820 dd9cb9c9f9b1b8e1dd7222f4e173125a 274 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 115 167 6.1E-4 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_1820 dd9cb9c9f9b1b8e1dd7222f4e173125a 274 SUPERFAMILY SSF51161 4 257 4.58E-76 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFE_1820 dd9cb9c9f9b1b8e1dd7222f4e173125a 274 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 5 274 2.3E-145 T 12-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.6E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.1E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 Gene3D G3DSA:3.40.50.720 2 246 2.2E-67 T 12-10-2018 AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 1.5E-48 T 12-10-2018 AFE_2801 1b1d7ea7646662e1c0c51a2cdb73b92b 247 SUPERFAMILY SSF51735 5 246 5.87E-65 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2372 ae6232521e00fff500095af9f8d2e410 537 Gene3D G3DSA:1.20.1260.30 1 195 1.4E-49 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily AFE_2372 ae6232521e00fff500095af9f8d2e410 537 Gene3D G3DSA:3.40.50.150 200 493 5.6E-86 T 12-10-2018 AFE_2372 ae6232521e00fff500095af9f8d2e410 537 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 7 513 3.4E-120 T 12-10-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 AFE_2372 ae6232521e00fff500095af9f8d2e410 537 SUPERFAMILY SSF53335 8 533 1.92E-130 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2372 ae6232521e00fff500095af9f8d2e410 537 Pfam PF12161 HsdM N-terminal domain 9 168 7.7E-27 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain AFE_2372 ae6232521e00fff500095af9f8d2e410 537 Pfam PF02384 N-6 DNA Methylase 179 499 1.9E-102 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 AFE_2372 ae6232521e00fff500095af9f8d2e410 537 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 317 329 6.9E-20 T 12-10-2018 AFE_2372 ae6232521e00fff500095af9f8d2e410 537 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 352 376 6.9E-20 T 12-10-2018 AFE_2372 ae6232521e00fff500095af9f8d2e410 537 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 202 218 6.9E-20 T 12-10-2018 AFE_2372 ae6232521e00fff500095af9f8d2e410 537 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 236 250 6.9E-20 T 12-10-2018 AFE_2372 ae6232521e00fff500095af9f8d2e410 537 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 320 326 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFE_0466 a52ab1899735ab209c40b00805bce795 471 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 5.3E-30 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFE_0466 a52ab1899735ab209c40b00805bce795 471 Pfam PF00120 Glutamine synthetase, catalytic domain 104 468 1.1E-136 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFE_0466 a52ab1899735ab209c40b00805bce795 471 SMART SM01230 104 381 3.2E-150 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFE_0466 a52ab1899735ab209c40b00805bce795 471 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 388 400 - T 12-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFE_0466 a52ab1899735ab209c40b00805bce795 471 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFE_0466 a52ab1899735ab209c40b00805bce795 471 SUPERFAMILY SSF55931 104 470 2.84E-137 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFE_0466 a52ab1899735ab209c40b00805bce795 471 Gene3D G3DSA:3.30.590.10 107 459 2.1E-145 T 12-10-2018 AFE_0466 a52ab1899735ab209c40b00805bce795 471 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 12-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFE_0466 a52ab1899735ab209c40b00805bce795 471 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 470 6.1E-201 T 12-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFE_0466 a52ab1899735ab209c40b00805bce795 471 SUPERFAMILY SSF54368 5 102 4.84E-35 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFE_0466 a52ab1899735ab209c40b00805bce795 471 Gene3D G3DSA:3.10.20.70 4 106 3.1E-37 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFE_1754 6f3552905dae35f2d0c2d229f55fcf75 104 SUPERFAMILY SSF47413 13 96 3.44E-23 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_1754 6f3552905dae35f2d0c2d229f55fcf75 104 SMART SM00530 18 73 6.7E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_1754 6f3552905dae35f2d0c2d229f55fcf75 104 Pfam PF01381 Helix-turn-helix 20 71 4.6E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_1754 6f3552905dae35f2d0c2d229f55fcf75 104 Gene3D G3DSA:1.10.260.40 6 103 5.0E-28 T 12-10-2018 AFE_1754 6f3552905dae35f2d0c2d229f55fcf75 104 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 11 87 8.6E-30 T 12-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 Gene3D G3DSA:3.50.50.60 15 316 2.6E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0375 485dc06b2786e35b212d27b5c2850429 323 SUPERFAMILY SSF51905 10 317 9.97E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 2.0E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 135 147 2.0E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 262 2.0E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 202 218 2.0E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 280 298 2.0E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 14 36 2.0E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 68 78 2.0E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 150 174 2.0E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 47 62 2.0E-76 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 Gene3D G3DSA:3.50.50.60 124 247 2.6E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0375 485dc06b2786e35b212d27b5c2850429 323 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 142 162 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 305 1.4E-47 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 15 317 8.1E-121 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 3.3E-37 T 12-10-2018 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 3.3E-37 T 12-10-2018 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 3.3E-37 T 12-10-2018 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 3.3E-37 T 12-10-2018 AFE_0375 485dc06b2786e35b212d27b5c2850429 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 3.3E-37 T 12-10-2018 AFE_3253 eaec4b127338559f94004c3f6e29864b 314 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 6 310 3.3E-114 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 AFE_3253 eaec4b127338559f94004c3f6e29864b 314 SUPERFAMILY SSF56655 4 312 4.82E-80 T 12-10-2018 AFE_3253 eaec4b127338559f94004c3f6e29864b 314 Gene3D G3DSA:3.40.190.90 112 266 2.3E-112 T 12-10-2018 AFE_3253 eaec4b127338559f94004c3f6e29864b 314 Gene3D G3DSA:3.30.540.10 9 309 2.3E-112 T 12-10-2018 AFE_3253 eaec4b127338559f94004c3f6e29864b 314 PIRSF PIRSF004532 4 314 5.4E-113 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 AFE_3253 eaec4b127338559f94004c3f6e29864b 314 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 6 311 8.2E-93 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 AFE_1706 894a3150f33534282469354c8fc89e43 545 Pfam PF13007 Transposase C of IS166 homeodomain 54 147 2.4E-18 T 12-10-2018 IPR024463 Transposase TnpC, homeodomain AFE_1706 894a3150f33534282469354c8fc89e43 545 Pfam PF13817 IS66 C-terminal element 500 537 1.8E-18 T 12-10-2018 IPR039552 Transposase IS66, C-terminal AFE_1706 894a3150f33534282469354c8fc89e43 545 Pfam PF03050 Transposase IS66 family 211 493 5.4E-99 T 12-10-2018 IPR004291 Transposase, IS66 AFE_1706 894a3150f33534282469354c8fc89e43 545 Pfam PF13005 zinc-finger binding domain of transposase IS66 154 197 3.9E-16 T 12-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFE_1614 8df8e7825a5883de0f50ae382abbac6f 154 Pfam PF12728 Helix-turn-helix domain 83 130 6.8E-12 T 12-10-2018 AFE_1614 8df8e7825a5883de0f50ae382abbac6f 154 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 83 130 2.2E-16 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 AFE_0451 6a83049dd02bd3bf2cc1fb4a4baa13a2 295 Pfam PF01513 ATP-NAD kinase 60 272 1.0E-57 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFE_0451 6a83049dd02bd3bf2cc1fb4a4baa13a2 295 Hamap MF_00361 NAD kinase [nadK]. 6 288 31.015 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFE_0451 6a83049dd02bd3bf2cc1fb4a4baa13a2 295 Gene3D G3DSA:3.40.50.10330 25 288 1.2E-84 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFE_0451 6a83049dd02bd3bf2cc1fb4a4baa13a2 295 SUPERFAMILY SSF111331 7 289 3.01E-79 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFE_0451 6a83049dd02bd3bf2cc1fb4a4baa13a2 295 Gene3D G3DSA:2.60.200.30 129 265 1.2E-84 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFE_0673 982d712d8d1529aa8b62fe4de2b9b530 407 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 7 407 2.6E-212 T 12-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 AFE_0673 982d712d8d1529aa8b62fe4de2b9b530 407 Gene3D G3DSA:3.90.1150.10 9 377 6.9E-158 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0673 982d712d8d1529aa8b62fe4de2b9b530 407 Pfam PF00266 Aminotransferase class-V 9 371 3.3E-87 T 12-10-2018 IPR000192 Aminotransferase class V domain AFE_0673 982d712d8d1529aa8b62fe4de2b9b530 407 Gene3D G3DSA:3.40.640.10 20 264 6.9E-158 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_0673 982d712d8d1529aa8b62fe4de2b9b530 407 SUPERFAMILY SSF53383 6 394 8.68E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_0673 982d712d8d1529aa8b62fe4de2b9b530 407 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 5 398 53.766 T 12-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 AFE_0673 982d712d8d1529aa8b62fe4de2b9b530 407 PIRSF PIRSF005572 6 387 3.1E-130 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Gene3D G3DSA:1.10.150.390 1303 1362 2.9E-28 T 12-10-2018 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 SUPERFAMILY SSF64484 16 1351 0.0 T 12-10-2018 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Gene3D G3DSA:2.40.50.100 1139 1202 3.2E-64 T 12-10-2018 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Gene3D G3DSA:1.10.1790.20 1123 1301 3.2E-64 T 12-10-2018 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Gene3D G3DSA:1.10.132.30 628 777 8.3E-64 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 SMART SM00663 235 514 1.8E-184 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Gene3D G3DSA:2.40.50.100 1011 1114 2.1E-26 T 12-10-2018 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 3.6E-87 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Gene3D G3DSA:2.40.50.100 935 1010 1.7E-24 T 12-10-2018 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1354 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Pfam PF04998 RNA polymerase Rpb1, domain 5 753 1303 8.6E-74 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Gene3D G3DSA:1.10.274.100 551 627 1.3E-15 T 12-10-2018 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Pfam PF05000 RNA polymerase Rpb1, domain 4 660 750 3.1E-19 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 485 6.7E-35 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1363 19.005 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Gene3D G3DSA:1.10.274.100 490 550 7.3E-22 T 12-10-2018 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 631 5.7E-30 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0321 8972f2769adf4f2f76890c27643629ca 1384 Gene3D G3DSA:1.10.40.90 374 416 3.7E-23 T 12-10-2018 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 Gene3D G3DSA:3.30.450.20 354 476 8.0E-8 T 12-10-2018 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 670 688 2.2E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 659 669 2.2E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 641 655 2.2E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 SUPERFAMILY SSF55785 354 473 4.49E-8 T 12-10-2018 IPR035965 PAS domain superfamily AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 Gene3D G3DSA:3.30.565.10 556 710 2.6E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 SUPERFAMILY SSF158472 298 346 5.23E-7 T 12-10-2018 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 Pfam PF00672 HAMP domain 298 346 5.1E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 SMART SM00304 298 350 1.2E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 SMART SM00387 594 710 1.6E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 SUPERFAMILY SSF47384 478 551 9.02E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 SMART SM00388 483 554 2.0E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 Gene3D G3DSA:1.10.287.130 477 552 2.2E-10 T 12-10-2018 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 PIRSF PIRSF037532 4 710 1.8E-207 T 12-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 595 709 1.4E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 Pfam PF00512 His Kinase A (phospho-acceptor) domain 485 540 7.0E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 SUPERFAMILY SSF55874 551 709 7.47E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0023 6ae5b8a7248dd78c2d111490b1ef5912 710 Gene3D G3DSA:1.20.1480.50 267 353 4.3E-9 T 12-10-2018 AFE_0079 b702b30e53ddabc5d095a3c9d6a07879 403 SUPERFAMILY SSF53756 1 398 2.22E-71 T 12-10-2018 AFE_0079 b702b30e53ddabc5d095a3c9d6a07879 403 Pfam PF13579 Glycosyl transferase 4-like domain 16 195 1.1E-17 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_0079 b702b30e53ddabc5d095a3c9d6a07879 403 Gene3D G3DSA:3.40.50.2000 222 377 5.5E-39 T 12-10-2018 AFE_0079 b702b30e53ddabc5d095a3c9d6a07879 403 Pfam PF00534 Glycosyl transferases group 1 229 375 1.1E-30 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_0079 b702b30e53ddabc5d095a3c9d6a07879 403 Gene3D G3DSA:3.40.50.2000 1 213 1.6E-19 T 12-10-2018 AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 Pfam PF13086 AAA domain 1537 1584 9.9E-9 T 12-10-2018 AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 Pfam PF11784 Protein of unknown function (DUF3320) 2047 2096 2.3E-21 T 12-10-2018 IPR021754 Protein of unknown function DUF3320 AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 SUPERFAMILY SSF52540 1528 1827 2.03E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 SUPERFAMILY SSF52540 661 761 3.73E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 SUPERFAMILY SSF52980 1841 1947 1.55E-14 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 Gene3D G3DSA:3.40.960.10 1845 1950 1.6E-14 T 12-10-2018 AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 Pfam PF13195 Protein of unknown function (DUF4011) 397 569 2.4E-44 T 12-10-2018 IPR025103 Protein of unknown function DUF4011 AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 Pfam PF13087 AAA domain 1615 1801 9.0E-14 T 12-10-2018 AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 Gene3D G3DSA:3.40.50.300 1627 1820 1.7E-27 T 12-10-2018 AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 Gene3D G3DSA:3.40.50.300 614 831 1.3E-16 T 12-10-2018 AFE_1572 9fde0cd6141c6312c8e3b7525d83f53a 2198 Gene3D G3DSA:3.40.50.300 1359 1604 3.9E-17 T 12-10-2018 AFE_2069 9a2341062953aaefb7afd2e35a8ca4f2 399 Gene3D G3DSA:3.40.50.1100 14 210 8.1E-190 T 12-10-2018 AFE_2069 9a2341062953aaefb7afd2e35a8ca4f2 399 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 85 99 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFE_2069 9a2341062953aaefb7afd2e35a8ca4f2 399 Gene3D G3DSA:3.40.50.1100 58 388 8.1E-190 T 12-10-2018 AFE_2069 9a2341062953aaefb7afd2e35a8ca4f2 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 382 1.9E-49 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFE_2069 9a2341062953aaefb7afd2e35a8ca4f2 399 SUPERFAMILY SSF53686 7 392 4.45E-150 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFE_2069 9a2341062953aaefb7afd2e35a8ca4f2 399 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 6 395 53.87 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFE_2069 9a2341062953aaefb7afd2e35a8ca4f2 399 PIRSF PIRSF001413 3 399 4.6E-168 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFE_2069 9a2341062953aaefb7afd2e35a8ca4f2 399 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 11 393 1.9E-191 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFE_2819 15d798606ce728a1ba8d13c56ee6675d 457 Gene3D G3DSA:3.40.50.300 175 453 3.0E-106 T 12-10-2018 AFE_2819 15d798606ce728a1ba8d13c56ee6675d 457 SMART SM00382 209 406 4.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2819 15d798606ce728a1ba8d13c56ee6675d 457 Pfam PF03796 DnaB-like helicase C terminal domain 192 447 8.6E-113 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 AFE_2819 15d798606ce728a1ba8d13c56ee6675d 457 SUPERFAMILY SSF52540 190 440 8.91E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2819 15d798606ce728a1ba8d13c56ee6675d 457 Pfam PF00772 DnaB-like helicase N terminal domain 14 115 1.1E-35 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 AFE_2819 15d798606ce728a1ba8d13c56ee6675d 457 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 14 449 5.7E-174 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 AFE_2819 15d798606ce728a1ba8d13c56ee6675d 457 SUPERFAMILY SSF48024 12 123 8.24E-37 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 AFE_2819 15d798606ce728a1ba8d13c56ee6675d 457 Gene3D G3DSA:1.10.860.10 10 173 1.3E-53 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal AFE_0442 29fb6e5528a56d53968185266c15c059 289 Gene3D G3DSA:3.90.25.10 160 281 7.3E-94 T 12-10-2018 AFE_0442 29fb6e5528a56d53968185266c15c059 289 Gene3D G3DSA:3.40.50.720 4 273 7.3E-94 T 12-10-2018 AFE_0442 29fb6e5528a56d53968185266c15c059 289 SUPERFAMILY SSF51735 1 285 5.65E-90 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0442 29fb6e5528a56d53968185266c15c059 289 Pfam PF04321 RmlD substrate binding domain 3 285 4.8E-92 T 12-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 AFE_0442 29fb6e5528a56d53968185266c15c059 289 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 285 9.8E-95 T 12-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 AFE_2525 87e9ecee58b1c878b47456d29fb9b5cb 99 SUPERFAMILY SSF46785 2 69 3.54E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2525 87e9ecee58b1c878b47456d29fb9b5cb 99 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 61 69 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFE_2525 87e9ecee58b1c878b47456d29fb9b5cb 99 Pfam PF09012 FeoC like transcriptional regulator 4 73 1.3E-9 T 12-10-2018 IPR015102 Transcriptional regulator HTH-type, FeoC AFE_2525 87e9ecee58b1c878b47456d29fb9b5cb 99 Gene3D G3DSA:1.10.10.10 1 82 1.3E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 Gene3D G3DSA:3.40.50.970 311 481 6.8E-65 T 12-10-2018 AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 SUPERFAMILY SSF52518 2 375 2.43E-76 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 ProSitePatterns PS00802 Transketolase signature 2. 419 435 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 Pfam PF02779 Transketolase, pyrimidine binding domain 313 473 3.0E-37 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 Gene3D G3DSA:3.40.50.920 490 616 2.2E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 5 276 3.5E-116 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 SUPERFAMILY SSF52518 312 500 4.98E-59 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 Pfam PF02780 Transketolase, C-terminal domain 490 606 7.9E-26 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 SMART SM00861 313 477 3.4E-66 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 7 611 3.3E-264 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 ProSitePatterns PS00801 Transketolase signature 1. 30 49 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 SUPERFAMILY SSF52922 486 614 1.44E-31 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_1974 722d27dcbaef6102059e76dfef129f3a 624 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 4 615 45.256 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFE_3285 de3433b4ea1bc111cdd656c8930478cd 453 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 130 141 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_3285 de3433b4ea1bc111cdd656c8930478cd 453 SUPERFAMILY SSF54862 54 169 6.7E-15 T 12-10-2018 AFE_3285 de3433b4ea1bc111cdd656c8930478cd 453 Gene3D G3DSA:1.10.1060.10 114 162 2.2E-5 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_3285 de3433b4ea1bc111cdd656c8930478cd 453 Pfam PF02754 Cysteine-rich domain 337 424 6.1E-13 T 12-10-2018 IPR004017 Cysteine-rich domain AFE_3285 de3433b4ea1bc111cdd656c8930478cd 453 Pfam PF13183 4Fe-4S dicluster domain 57 144 4.9E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_2123 c734878425d66c3be85722e6a4746716 237 TIGRFAM TIGR03468 HpnG: hopanoid-associated phosphorylase 18 226 4.2E-75 T 12-10-2018 IPR017831 Hopanoid-associated phosphorylase HpnG AFE_2123 c734878425d66c3be85722e6a4746716 237 Pfam PF01048 Phosphorylase superfamily 34 178 4.1E-21 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFE_2123 c734878425d66c3be85722e6a4746716 237 SUPERFAMILY SSF53167 4 196 4.45E-31 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFE_2123 c734878425d66c3be85722e6a4746716 237 Gene3D G3DSA:3.40.50.1580 3 187 8.7E-25 T 12-10-2018 AFE_3191 8cd3d5f21312e19290b4e943dfc27cbc 908 Gene3D G3DSA:3.40.50.300 366 557 1.2E-16 T 12-10-2018 AFE_3191 8cd3d5f21312e19290b4e943dfc27cbc 908 SUPERFAMILY SSF52540 136 531 6.07E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3191 8cd3d5f21312e19290b4e943dfc27cbc 908 Pfam PF04851 Type III restriction enzyme, res subunit 93 337 5.1E-19 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFE_3191 8cd3d5f21312e19290b4e943dfc27cbc 908 SUPERFAMILY SSF52540 88 340 1.77E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3191 8cd3d5f21312e19290b4e943dfc27cbc 908 Gene3D G3DSA:3.40.50.300 83 357 1.8E-6 T 12-10-2018 AFE_2852 276003842dc45dd3606554db3e1f9339 114 Pfam PF01245 Ribosomal protein L19 2 112 1.9E-50 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2852 276003842dc45dd3606554db3e1f9339 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2852 276003842dc45dd3606554db3e1f9339 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 30.451 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2852 276003842dc45dd3606554db3e1f9339 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 112 3.5E-50 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2852 276003842dc45dd3606554db3e1f9339 114 PIRSF PIRSF002191 1 114 5.9E-51 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2852 276003842dc45dd3606554db3e1f9339 114 SUPERFAMILY SSF50104 1 113 9.83E-48 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFE_2852 276003842dc45dd3606554db3e1f9339 114 Gene3D G3DSA:2.30.30.790 4 113 3.8E-15 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2852 276003842dc45dd3606554db3e1f9339 114 PRINTS PR00061 Ribosomal protein L19 signature 87 112 7.5E-40 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2852 276003842dc45dd3606554db3e1f9339 114 PRINTS PR00061 Ribosomal protein L19 signature 3 32 7.5E-40 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2852 276003842dc45dd3606554db3e1f9339 114 PRINTS PR00061 Ribosomal protein L19 signature 33 62 7.5E-40 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0158 b15eb030de76eee0f0bf29a2f3013e7a 276 Pfam PF00005 ABC transporter 24 172 2.4E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0158 b15eb030de76eee0f0bf29a2f3013e7a 276 SMART SM00382 33 230 4.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0158 b15eb030de76eee0f0bf29a2f3013e7a 276 SUPERFAMILY SSF52540 8 237 4.28E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0158 b15eb030de76eee0f0bf29a2f3013e7a 276 Gene3D G3DSA:3.40.50.300 6 251 4.7E-62 T 12-10-2018 AFE_3294 fb1fd9c898d6c22c732d10613203f775 182 SUPERFAMILY SSF51182 1 177 1.5E-74 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_3294 fb1fd9c898d6c22c732d10613203f775 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 175 3.0E-72 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AFE_3294 fb1fd9c898d6c22c732d10613203f775 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 176 1.0E-79 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AFE_3294 fb1fd9c898d6c22c732d10613203f775 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 181 8.0E-69 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 AFE_3294 fb1fd9c898d6c22c732d10613203f775 182 Gene3D G3DSA:2.60.120.10 1 182 2.4E-70 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 Gene3D G3DSA:3.50.7.10 192 372 2.1E-239 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 SUPERFAMILY SSF48592 8 521 7.63E-77 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 1.5E-259 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 SUPERFAMILY SSF52029 185 376 3.29E-84 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 Hamap MF_00600 60 kDa chaperonin [groL]. 2 551 41.732 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 PRINTS PR00298 60kDa chaperonin signature 350 375 7.4E-74 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 PRINTS PR00298 60kDa chaperonin signature 398 419 7.4E-74 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 PRINTS PR00298 60kDa chaperonin signature 27 53 7.4E-74 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 PRINTS PR00298 60kDa chaperonin signature 83 110 7.4E-74 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 PRINTS PR00298 60kDa chaperonin signature 268 291 7.4E-74 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 Gene3D G3DSA:3.30.260.10 136 410 2.1E-239 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 SUPERFAMILY SSF54849 137 204 1.1E-24 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 2.1E-95 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 AFE_0542 b2da45b3d4ba9deb58d3141bfcc7822e 551 Gene3D G3DSA:1.10.560.10 8 521 2.1E-239 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 248 260 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 273 288 1.6E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 127 141 1.6E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 196 215 1.6E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 248 264 1.6E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 303 322 1.6E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 158 177 1.6E-57 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 Pfam PF00490 Delta-aminolevulinic acid dehydratase 11 328 1.2E-139 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 PIRSF PIRSF001415 3 330 3.6E-141 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 SMART SM01004 11 329 5.4E-205 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 SUPERFAMILY SSF51569 10 329 3.66E-134 T 12-10-2018 AFE_3298 d9cd4fdc4a3ef4787831d681a17092cb 330 Gene3D G3DSA:3.20.20.70 5 330 3.9E-140 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_0640 44b791c412787c96d2540140c3f3c225 380 Gene3D G3DSA:3.40.50.880 150 375 2.1E-68 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_0640 44b791c412787c96d2540140c3f3c225 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 261 272 1.8E-9 T 12-10-2018 AFE_0640 44b791c412787c96d2540140c3f3c225 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 233 242 1.8E-9 T 12-10-2018 AFE_0640 44b791c412787c96d2540140c3f3c225 380 PRINTS PR00096 Glutamine amidotransferase superfamily signature 346 359 1.8E-9 T 12-10-2018 AFE_0640 44b791c412787c96d2540140c3f3c225 380 SMART SM01097 1 131 5.5E-84 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0640 44b791c412787c96d2540140c3f3c225 380 Gene3D G3DSA:3.50.30.20 1 149 1.1E-56 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0640 44b791c412787c96d2540140c3f3c225 380 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 129 8.2E-50 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0640 44b791c412787c96d2540140c3f3c225 380 Pfam PF00117 Glutamine amidotransferase class-I 193 369 7.5E-43 T 12-10-2018 IPR017926 Glutamine amidotransferase AFE_0640 44b791c412787c96d2540140c3f3c225 380 SUPERFAMILY SSF52317 182 374 9.85E-58 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_0640 44b791c412787c96d2540140c3f3c225 380 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 375 47.243 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0640 44b791c412787c96d2540140c3f3c225 380 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 372 1.5E-139 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0640 44b791c412787c96d2540140c3f3c225 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 230 244 2.0E-37 T 12-10-2018 AFE_0640 44b791c412787c96d2540140c3f3c225 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 191 205 2.0E-37 T 12-10-2018 AFE_0640 44b791c412787c96d2540140c3f3c225 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 303 314 2.0E-37 T 12-10-2018 AFE_0640 44b791c412787c96d2540140c3f3c225 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 278 295 2.0E-37 T 12-10-2018 AFE_0640 44b791c412787c96d2540140c3f3c225 380 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 261 277 2.0E-37 T 12-10-2018 AFE_0640 44b791c412787c96d2540140c3f3c225 380 SUPERFAMILY SSF52021 1 139 3.79E-54 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0526 37463403108309c9af56ac2b476d4587 509 Gene3D G3DSA:3.40.720.10 7 506 2.1E-203 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_0526 37463403108309c9af56ac2b476d4587 509 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 84 295 7.9E-72 T 12-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0526 37463403108309c9af56ac2b476d4587 509 SUPERFAMILY SSF53649 6 506 3.27E-72 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFE_0526 37463403108309c9af56ac2b476d4587 509 PIRSF PIRSF001492 1 508 1.7E-190 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0526 37463403108309c9af56ac2b476d4587 509 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 6 507 48.497 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0526 37463403108309c9af56ac2b476d4587 509 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 7 506 2.8E-207 T 12-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0526 37463403108309c9af56ac2b476d4587 509 Pfam PF01676 Metalloenzyme superfamily 7 494 2.8E-72 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 AFE_0526 37463403108309c9af56ac2b476d4587 509 SUPERFAMILY SSF64158 79 306 1.09E-77 T 12-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0526 37463403108309c9af56ac2b476d4587 509 Gene3D G3DSA:3.40.1450.10 79 308 2.1E-203 T 12-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_0259 5db3582579ebe7073a1406d11c3f561a 316 Pfam PF04055 Radical SAM superfamily 51 208 2.2E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_0259 5db3582579ebe7073a1406d11c3f561a 316 SUPERFAMILY SSF102114 9 311 2.09E-88 T 12-10-2018 AFE_0259 5db3582579ebe7073a1406d11c3f561a 316 Gene3D G3DSA:3.20.20.70 7 315 7.6E-121 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_0259 5db3582579ebe7073a1406d11c3f561a 316 SMART SM00876 221 313 3.8E-43 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFE_0259 5db3582579ebe7073a1406d11c3f561a 316 Hamap MF_01694 Biotin synthase [bioB]. 6 314 41.208 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFE_0259 5db3582579ebe7073a1406d11c3f561a 316 SMART SM00729 44 256 2.3E-35 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFE_0259 5db3582579ebe7073a1406d11c3f561a 316 PIRSF PIRSF001619 1 316 2.3E-123 T 12-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFE_0259 5db3582579ebe7073a1406d11c3f561a 316 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 221 311 2.0E-18 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFE_0259 5db3582579ebe7073a1406d11c3f561a 316 TIGRFAM TIGR00433 bioB: biotin synthase 15 311 6.0E-119 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 Gene3D G3DSA:3.30.540.10 2 196 2.3E-67 T 12-10-2018 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 5 334 45.742 T 12-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 30 57 2.6E-69 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 180 203 2.6E-69 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 308 333 2.6E-69 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 149 172 2.6E-69 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 206 233 2.6E-69 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 67 93 2.6E-69 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 PIRSF PIRSF500210 1 336 8.6E-122 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 SUPERFAMILY SSF56655 5 332 1.35E-112 T 12-10-2018 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 PIRSF PIRSF000904 1 336 2.8E-119 T 12-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 274 286 - T 12-10-2018 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 6 194 6.8E-60 T 12-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 AFE_0189 3db87410e4747ad3e6a4e43528b664ae 339 Gene3D G3DSA:3.40.190.80 197 334 5.7E-55 T 12-10-2018 AFE_0069 399daf4232c853608aa5ba35ab6b97d4 214 Gene3D G3DSA:3.20.20.70 5 208 2.8E-36 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_0069 399daf4232c853608aa5ba35ab6b97d4 214 PIRSF PIRSF000370 3 213 9.3E-65 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AFE_0069 399daf4232c853608aa5ba35ab6b97d4 214 Pfam PF04055 Radical SAM superfamily 28 104 1.9E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_0069 399daf4232c853608aa5ba35ab6b97d4 214 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 5 211 35.414 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AFE_0069 399daf4232c853608aa5ba35ab6b97d4 214 Pfam PF13394 4Fe-4S single cluster domain 27 107 6.4E-9 T 12-10-2018 AFE_0069 399daf4232c853608aa5ba35ab6b97d4 214 SUPERFAMILY SSF102114 22 104 1.18E-12 T 12-10-2018 AFE_0069 399daf4232c853608aa5ba35ab6b97d4 214 TIGRFAM TIGR04349 rSAM_QueE_gams: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 5 214 1.2E-106 T 12-10-2018 IPR027621 Putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 SMART SM00480 17 361 1.2E-81 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 SUPERFAMILY SSF55979 244 365 1.36E-28 T 12-10-2018 AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 244 364 1.4E-22 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 SUPERFAMILY SSF55979 1 116 6.52E-23 T 12-10-2018 AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 Pfam PF02767 DNA polymerase III beta subunit, central domain 131 242 1.9E-26 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 Gene3D G3DSA:3.70.10.10 137 363 9.4E-98 T 12-10-2018 AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 SUPERFAMILY SSF55979 130 246 2.01E-22 T 12-10-2018 AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 365 1.0E-86 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 PIRSF PIRSF000804 1 365 1.0E-99 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 118 2.8E-26 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 AFE_0001 9872832ab96d6ad99616ab74bd0f694f 365 Gene3D G3DSA:3.10.150.10 1 241 9.4E-98 T 12-10-2018 AFE_0545 d9ee0f8b29fa0722dfb4abbeedc703fe 616 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 212 417 1.4E-15 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 AFE_0545 d9ee0f8b29fa0722dfb4abbeedc703fe 616 Pfam PF11412 Disulphide bond corrector protein DsbC 44 159 9.1E-30 T 12-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain AFE_0545 d9ee0f8b29fa0722dfb4abbeedc703fe 616 Gene3D G3DSA:3.40.30.10 496 616 6.5E-27 T 12-10-2018 AFE_0545 d9ee0f8b29fa0722dfb4abbeedc703fe 616 Gene3D G3DSA:2.60.40.1250 38 175 6.3E-36 T 12-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily AFE_0545 d9ee0f8b29fa0722dfb4abbeedc703fe 616 SUPERFAMILY SSF52833 502 614 1.61E-20 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0545 d9ee0f8b29fa0722dfb4abbeedc703fe 616 Pfam PF13899 Thioredoxin-like 519 579 7.3E-9 T 12-10-2018 AFE_0545 d9ee0f8b29fa0722dfb4abbeedc703fe 616 SUPERFAMILY SSF74863 42 159 1.7E-27 T 12-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 Pfam PF01018 GTP1/OBG 4 157 6.7E-58 T 12-10-2018 IPR006169 GTP1/OBG domain AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 Gene3D G3DSA:3.40.50.300 159 334 2.2E-51 T 12-10-2018 AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.7E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.7E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 3.7E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 3.7E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 SUPERFAMILY SSF82051 2 158 4.71E-54 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 1.3E-140 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 PIRSF PIRSF002401 1 362 2.6E-131 T 12-10-2018 IPR035101 GTP-binding protein, Obg-type AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 SUPERFAMILY SSF52540 151 336 1.59E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 Pfam PF01926 50S ribosome-binding GTPase 161 284 5.3E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 Gene3D G3DSA:2.70.210.12 1 158 5.7E-59 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily AFE_0283 c0337f6497c0d3ab49d81bfdb5db0632 374 Hamap MF_01454 GTPase Obg [obg]. 2 333 47.395 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AFE_2984 d1f8c511d1366c4c18fceb0ec3840385 150 SUPERFAMILY SSF88723 1 132 3.81E-12 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_2984 d1f8c511d1366c4c18fceb0ec3840385 150 Pfam PF01850 PIN domain 2 130 7.4E-11 T 12-10-2018 IPR002716 PIN domain AFE_2984 d1f8c511d1366c4c18fceb0ec3840385 150 Gene3D G3DSA:3.40.50.1010 1 125 1.6E-10 T 12-10-2018 AFE_0857 7d8af71b08f4c783d030e64f1012112c 229 Pfam PF00027 Cyclic nucleotide-binding domain 37 122 1.2E-16 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFE_0857 7d8af71b08f4c783d030e64f1012112c 229 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 176 192 2.2E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_0857 7d8af71b08f4c783d030e64f1012112c 229 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 192 207 2.2E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_0857 7d8af71b08f4c783d030e64f1012112c 229 Pfam PF13545 Crp-like helix-turn-helix domain 155 224 6.8E-18 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_0857 7d8af71b08f4c783d030e64f1012112c 229 SUPERFAMILY SSF46785 152 227 2.78E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0857 7d8af71b08f4c783d030e64f1012112c 229 Gene3D G3DSA:2.60.120.10 5 149 4.5E-35 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_0857 7d8af71b08f4c783d030e64f1012112c 229 SMART SM00100 17 135 2.7E-19 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFE_0857 7d8af71b08f4c783d030e64f1012112c 229 SMART SM00419 170 218 6.1E-12 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_0857 7d8af71b08f4c783d030e64f1012112c 229 Gene3D G3DSA:1.10.10.10 150 226 8.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0857 7d8af71b08f4c783d030e64f1012112c 229 SUPERFAMILY SSF51206 12 149 9.43E-29 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFE_1767 7e9e0cdd8706184445963b96d0b880df 220 SUPERFAMILY SSF53098 1 192 1.33E-27 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_1767 7e9e0cdd8706184445963b96d0b880df 220 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 180 202 8.3E-6 T 12-10-2018 IPR024530 Putative quorum-sensing-regulated virulence factor AFE_1767 7e9e0cdd8706184445963b96d0b880df 220 Pfam PF00929 Exonuclease 4 148 2.0E-5 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFE_1767 7e9e0cdd8706184445963b96d0b880df 220 SMART SM00479 2 163 7.2E-6 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFE_1767 7e9e0cdd8706184445963b96d0b880df 220 Gene3D G3DSA:3.30.420.10 4 173 5.3E-25 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_0112 a4c96620cb756307e0ce725fa5fcbec0 185 Gene3D G3DSA:1.25.40.10 85 185 3.2E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0112 a4c96620cb756307e0ce725fa5fcbec0 185 Gene3D G3DSA:1.20.58.320 4 84 3.1E-29 T 12-10-2018 AFE_0112 a4c96620cb756307e0ce725fa5fcbec0 185 Pfam PF06041 Bacterial protein of unknown function (DUF924) 12 182 8.4E-62 T 12-10-2018 IPR010323 Protein of unknown function DUF924 AFE_0112 a4c96620cb756307e0ce725fa5fcbec0 185 SUPERFAMILY SSF48452 7 181 2.92E-68 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1478 4dedfa243f907c1aff5fe5ff6320a4d8 432 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.5E-6 T 12-10-2018 AFE_1478 4dedfa243f907c1aff5fe5ff6320a4d8 432 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.5E-6 T 12-10-2018 AFE_1478 4dedfa243f907c1aff5fe5ff6320a4d8 432 SUPERFAMILY SSF51905 1 373 7.7E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1478 4dedfa243f907c1aff5fe5ff6320a4d8 432 Gene3D G3DSA:3.30.9.90 69 393 1.3E-66 T 12-10-2018 AFE_1478 4dedfa243f907c1aff5fe5ff6320a4d8 432 Gene3D G3DSA:3.50.50.60 5 364 1.3E-66 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1478 4dedfa243f907c1aff5fe5ff6320a4d8 432 Pfam PF01494 FAD binding domain 5 191 1.6E-8 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFE_1478 4dedfa243f907c1aff5fe5ff6320a4d8 432 SUPERFAMILY SSF54373 181 284 3.92E-23 T 12-10-2018 AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 12-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 Gene3D G3DSA:3.30.70.120 1 112 1.2E-45 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 PRINTS PR00340 P-II protein signature 2 17 2.4E-43 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 PRINTS PR00340 P-II protein signature 83 103 2.4E-43 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 PRINTS PR00340 P-II protein signature 23 41 2.4E-43 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 PRINTS PR00340 P-II protein signature 52 75 2.4E-43 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 5.3E-42 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 PIRSF PIRSF039144 1 112 8.0E-54 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 SUPERFAMILY SSF54913 1 112 1.24E-44 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFE_2915 d7b11dc8b485c0ffb7ff12bcfb34ac96 112 SMART SM00938 4 105 1.7E-65 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_0262 d7899e12490bc2450729140b441b4cda 275 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 267 8.0E-35 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFE_0262 d7899e12490bc2450729140b441b4cda 275 Gene3D G3DSA:3.40.50.720 3 165 1.0E-40 T 12-10-2018 AFE_0262 d7899e12490bc2450729140b441b4cda 275 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 267 25.343 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFE_0262 d7899e12490bc2450729140b441b4cda 275 SUPERFAMILY SSF51735 5 161 2.25E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0262 d7899e12490bc2450729140b441b4cda 275 Gene3D G3DSA:1.10.3730.10 166 270 9.1E-37 T 12-10-2018 AFE_0262 d7899e12490bc2450729140b441b4cda 275 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 267 2.5E-73 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFE_0262 d7899e12490bc2450729140b441b4cda 275 SUPERFAMILY SSF48179 163 268 7.82E-33 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFE_0262 d7899e12490bc2450729140b441b4cda 275 PIRSF PIRSF000193 3 270 1.9E-65 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFE_0262 d7899e12490bc2450729140b441b4cda 275 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 100 1.8E-11 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFE_0368 79d6e0d3f158accbffb609e106f54f1d 327 SUPERFAMILY SSF56784 116 322 4.67E-48 T 12-10-2018 IPR036412 HAD-like superfamily AFE_0368 79d6e0d3f158accbffb609e106f54f1d 327 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 117 313 2.3E-68 T 12-10-2018 AFE_0368 79d6e0d3f158accbffb609e106f54f1d 327 Gene3D G3DSA:3.40.50.1000 49 322 9.6E-72 T 12-10-2018 IPR023214 HAD superfamily AFE_0368 79d6e0d3f158accbffb609e106f54f1d 327 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 277 296 4.3E-5 T 12-10-2018 AFE_0368 79d6e0d3f158accbffb609e106f54f1d 327 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 203 213 4.3E-5 T 12-10-2018 AFE_0368 79d6e0d3f158accbffb609e106f54f1d 327 Pfam PF12710 haloacid dehalogenase-like hydrolase 120 288 2.9E-19 T 12-10-2018 AFE_0368 79d6e0d3f158accbffb609e106f54f1d 327 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 119 289 4.2E-31 T 12-10-2018 AFE_0242 761dd2f99703e19a212c2a6d76475eb4 263 SUPERFAMILY SSF53271 92 260 1.2E-27 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFE_0242 761dd2f99703e19a212c2a6d76475eb4 263 Gene3D G3DSA:3.40.50.2020 150 262 9.9E-15 T 12-10-2018 AFE_0284 13c870115ad89f3a815601c2e43890a0 86 SUPERFAMILY SSF110324 2 81 8.72E-34 T 12-10-2018 AFE_0284 13c870115ad89f3a815601c2e43890a0 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 3.0E-40 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0284 13c870115ad89f3a815601c2e43890a0 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 27.988 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0284 13c870115ad89f3a815601c2e43890a0 86 Pfam PF01016 Ribosomal L27 protein 2 77 4.6E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0284 13c870115ad89f3a815601c2e43890a0 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.8E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0284 13c870115ad89f3a815601c2e43890a0 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.8E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0284 13c870115ad89f3a815601c2e43890a0 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.8E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0284 13c870115ad89f3a815601c2e43890a0 86 Gene3D G3DSA:2.40.50.100 20 86 1.5E-29 T 12-10-2018 AFE_0284 13c870115ad89f3a815601c2e43890a0 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0284 13c870115ad89f3a815601c2e43890a0 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 5.0E-14 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2450 411f33ef19e368ad20d7ecb995abd390 100 PRINTS PR00606 Class ID cytochrome C signature 77 87 4.8E-9 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFE_2450 411f33ef19e368ad20d7ecb995abd390 100 PRINTS PR00606 Class ID cytochrome C signature 14 27 4.8E-9 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFE_2450 411f33ef19e368ad20d7ecb995abd390 100 PRINTS PR00606 Class ID cytochrome C signature 52 65 4.8E-9 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFE_2450 411f33ef19e368ad20d7ecb995abd390 100 PRINTS PR00606 Class ID cytochrome C signature 29 42 4.8E-9 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFE_2450 411f33ef19e368ad20d7ecb995abd390 100 Gene3D G3DSA:1.10.760.10 13 89 2.3E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_2450 411f33ef19e368ad20d7ecb995abd390 100 SUPERFAMILY SSF46626 15 88 2.13E-11 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_1583 05c30448f03c97bc1d59eb10bd2b98eb 107 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AFE_1583 05c30448f03c97bc1d59eb10bd2b98eb 107 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 8.7E-10 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1583 05c30448f03c97bc1d59eb10bd2b98eb 107 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 8.7E-10 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1583 05c30448f03c97bc1d59eb10bd2b98eb 107 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 8.7E-10 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1583 05c30448f03c97bc1d59eb10bd2b98eb 107 Gene3D G3DSA:4.10.520.10 1 96 1.0E-26 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_1583 05c30448f03c97bc1d59eb10bd2b98eb 107 SMART SM00411 3 92 1.3E-21 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1583 05c30448f03c97bc1d59eb10bd2b98eb 107 Pfam PF00216 Bacterial DNA-binding protein 4 90 7.6E-24 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1583 05c30448f03c97bc1d59eb10bd2b98eb 107 SUPERFAMILY SSF47729 3 92 2.21E-23 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_2462 f558f3d1049d9eff1a3095cbc0bb2b32 123 Gene3D G3DSA:3.30.70.120 1 112 3.4E-40 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFE_2462 f558f3d1049d9eff1a3095cbc0bb2b32 123 SUPERFAMILY SSF54913 1 111 6.04E-37 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFE_2462 f558f3d1049d9eff1a3095cbc0bb2b32 123 SMART SM00938 4 105 4.8E-47 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2462 f558f3d1049d9eff1a3095cbc0bb2b32 123 PRINTS PR00340 P-II protein signature 2 17 1.1E-31 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2462 f558f3d1049d9eff1a3095cbc0bb2b32 123 PRINTS PR00340 P-II protein signature 52 75 1.1E-31 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2462 f558f3d1049d9eff1a3095cbc0bb2b32 123 PRINTS PR00340 P-II protein signature 83 103 1.1E-31 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2462 f558f3d1049d9eff1a3095cbc0bb2b32 123 PRINTS PR00340 P-II protein signature 23 41 1.1E-31 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2462 f558f3d1049d9eff1a3095cbc0bb2b32 123 Pfam PF00543 Nitrogen regulatory protein P-II 5 105 8.0E-35 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2462 f558f3d1049d9eff1a3095cbc0bb2b32 123 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AFE_2439 30c87b3241dc9b0345823345429e5237 674 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 83 667 5.6E-186 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 101 666 3.6E-182 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFE_2439 30c87b3241dc9b0345823345429e5237 674 Pfam PF00702 haloacid dehalogenase-like hydrolase 359 573 4.6E-42 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 559 575 2.9E-10 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2439 30c87b3241dc9b0345823345429e5237 674 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 590 615 2.9E-10 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2439 30c87b3241dc9b0345823345429e5237 674 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 531 547 2.9E-10 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2439 30c87b3241dc9b0345823345429e5237 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 484 495 9.1E-30 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 362 376 9.1E-30 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 559 578 9.1E-30 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 506 516 9.1E-30 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 212 226 9.1E-30 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 582 594 9.1E-30 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 Pfam PF00122 E1-E2 ATPase 163 341 1.2E-49 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 130 666 1.9E-110 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 Gene3D G3DSA:2.70.150.20 150 266 5.5E-38 T 12-10-2018 AFE_2439 30c87b3241dc9b0345823345429e5237 674 Gene3D G3DSA:3.40.1110.10 373 491 3.2E-93 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_2439 30c87b3241dc9b0345823345429e5237 674 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 138 638 5.7E-88 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2439 30c87b3241dc9b0345823345429e5237 674 SUPERFAMILY SSF81653 165 262 1.26E-25 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFE_2439 30c87b3241dc9b0345823345429e5237 674 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 364 370 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFE_2439 30c87b3241dc9b0345823345429e5237 674 SUPERFAMILY SSF81665 102 630 2.88E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFE_2439 30c87b3241dc9b0345823345429e5237 674 SUPERFAMILY SSF56784 361 664 1.37E-55 T 12-10-2018 IPR036412 HAD-like superfamily AFE_2439 30c87b3241dc9b0345823345429e5237 674 Gene3D G3DSA:3.40.50.1000 356 609 3.2E-93 T 12-10-2018 IPR023214 HAD superfamily AFE_0243 95ed94bae93cae8de4a45504b695473e 389 Gene3D G3DSA:3.90.1150.10 47 381 7.9E-125 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0243 95ed94bae93cae8de4a45504b695473e 389 Pfam PF00155 Aminotransferase class I and II 47 383 1.8E-60 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFE_0243 95ed94bae93cae8de4a45504b695473e 389 SUPERFAMILY SSF53383 10 389 1.71E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_0243 95ed94bae93cae8de4a45504b695473e 389 Gene3D G3DSA:3.40.640.10 63 293 7.9E-125 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_0243 95ed94bae93cae8de4a45504b695473e 389 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 242 251 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 AFE_0243 95ed94bae93cae8de4a45504b695473e 389 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 40 385 2.9E-130 T 12-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 AFE_0243 95ed94bae93cae8de4a45504b695473e 389 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 5 389 46.235 T 12-10-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 165 322 1.1E-20 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 Gene3D G3DSA:1.10.287.470 180 209 3.2E-26 T 12-10-2018 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 Gene3D G3DSA:1.10.287.470 107 175 3.6E-10 T 12-10-2018 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 SUPERFAMILY SSF111369 180 329 1.7E-9 T 12-10-2018 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 Gene3D G3DSA:2.40.30.170 245 331 3.2E-26 T 12-10-2018 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 Gene3D G3DSA:2.40.50.100 210 244 3.2E-26 T 12-10-2018 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 Pfam PF13533 Biotin-lipoyl like 47 98 2.6E-9 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 Gene3D G3DSA:2.40.50.100 46 79 3.2E-9 T 12-10-2018 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 SUPERFAMILY SSF111369 116 173 7.45E-6 T 12-10-2018 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 58 78 6.3E-5 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 318 333 6.3E-5 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 Gene3D G3DSA:1.10.287.470 80 103 3.2E-9 T 12-10-2018 AFE_2861 477b9c30736cb0a80ffe0cf4fd22676b 345 SUPERFAMILY SSF111369 50 104 1.44E-5 T 12-10-2018 AFE_2696 cb1528a1266f651aad37b84691beb055 462 Gene3D G3DSA:3.40.50.300 137 319 9.3E-53 T 12-10-2018 AFE_2696 cb1528a1266f651aad37b84691beb055 462 SUPERFAMILY SSF46689 408 460 9.86E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_2696 cb1528a1266f651aad37b84691beb055 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 424 441 1.9E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_2696 cb1528a1266f651aad37b84691beb055 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 441 461 1.9E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_2696 cb1528a1266f651aad37b84691beb055 462 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 365 374 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_2696 cb1528a1266f651aad37b84691beb055 462 SUPERFAMILY SSF52540 146 387 3.73E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2696 cb1528a1266f651aad37b84691beb055 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 234 249 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFE_2696 cb1528a1266f651aad37b84691beb055 462 Pfam PF02954 Bacterial regulatory protein, Fis family 422 458 3.2E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_2696 cb1528a1266f651aad37b84691beb055 462 Pfam PF00158 Sigma-54 interaction domain 149 314 1.9E-54 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_2696 cb1528a1266f651aad37b84691beb055 462 Gene3D G3DSA:1.10.10.60 415 461 8.4E-11 T 12-10-2018 AFE_2696 cb1528a1266f651aad37b84691beb055 462 SMART SM00382 167 311 1.1E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2136 3e07f9b720d963606246dec0ed256a71 217 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 10 175 2.0E-41 T 12-10-2018 AFE_2136 3e07f9b720d963606246dec0ed256a71 217 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 132 147 - T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AFE_2136 3e07f9b720d963606246dec0ed256a71 217 Gene3D G3DSA:3.40.50.150 1 210 9.9E-52 T 12-10-2018 AFE_2136 3e07f9b720d963606246dec0ed256a71 217 SUPERFAMILY SSF53335 1 208 1.74E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_1655 7bd609267328b480a3860826eb6c8b73 230 Gene3D G3DSA:3.30.420.470 23 220 4.1E-12 T 12-10-2018 AFE_1655 7bd609267328b480a3860826eb6c8b73 230 SUPERFAMILY SSF53098 107 217 1.39E-5 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_1655 7bd609267328b480a3860826eb6c8b73 230 Pfam PF13592 Winged helix-turn helix 4 39 8.1E-9 T 12-10-2018 IPR025959 Winged helix-turn helix domain AFE_1655 7bd609267328b480a3860826eb6c8b73 230 Pfam PF13358 DDE superfamily endonuclease 55 186 1.8E-34 T 12-10-2018 IPR038717 Tc1-like transposase, DDE domain AFE_2903 2207bac19b54b1b07020147711fd6a9a 256 PIRSF PIRSF009120 1 249 8.0E-93 T 12-10-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 AFE_2903 2207bac19b54b1b07020147711fd6a9a 256 Pfam PF00227 Proteasome subunit 9 189 3.9E-5 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFE_2903 2207bac19b54b1b07020147711fd6a9a 256 SUPERFAMILY SSF56235 2 241 4.59E-30 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_2903 2207bac19b54b1b07020147711fd6a9a 256 Gene3D G3DSA:3.60.20.10 2 208 2.6E-23 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 2.6E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 PRINTS PR00834 HtrA/DegQ protease family signature 170 194 2.6E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 PRINTS PR00834 HtrA/DegQ protease family signature 312 324 2.6E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 PRINTS PR00834 HtrA/DegQ protease family signature 130 150 2.6E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 PRINTS PR00834 HtrA/DegQ protease family signature 204 221 2.6E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 PRINTS PR00834 HtrA/DegQ protease family signature 109 121 2.6E-43 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 Gene3D G3DSA:2.30.42.10 268 370 6.1E-24 T 12-10-2018 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 Gene3D G3DSA:2.40.10.120 31 265 6.9E-77 T 12-10-2018 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 32 474 1.5E-140 T 12-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 Gene3D G3DSA:2.30.42.10 392 475 3.7E-16 T 12-10-2018 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 SUPERFAMILY SSF50156 409 476 9.86E-14 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 SUPERFAMILY SSF50156 230 355 2.5E-23 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 Pfam PF13180 PDZ domain 409 467 2.3E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 Pfam PF13180 PDZ domain 283 361 9.8E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 SUPERFAMILY SSF50494 30 263 2.24E-60 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 Pfam PF13365 Trypsin-like peptidase domain 100 233 4.4E-33 T 12-10-2018 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 SMART SM00228 272 354 2.4E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_1396 ec1725c4ec2d5d666292378f2261003e 479 SMART SM00228 355 468 2.2E-5 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_1399 8c3467ff293b041986219e5f18252062 144 Pfam PF16137 Domain of unknown function (DUF4845) 56 139 1.5E-20 T 12-10-2018 IPR032314 Protein of unknown function DUF4845 AFE_0718 9f633ce428a4ab32ba2a5f2bbc32bb2c 257 Gene3D G3DSA:3.40.50.300 41 251 1.1E-63 T 12-10-2018 AFE_0718 9f633ce428a4ab32ba2a5f2bbc32bb2c 257 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 32 243 5.1E-82 T 12-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 AFE_0718 9f633ce428a4ab32ba2a5f2bbc32bb2c 257 SUPERFAMILY SSF52540 38 245 1.29E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0718 9f633ce428a4ab32ba2a5f2bbc32bb2c 257 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 62 223 3.5E-33 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFE_0718 9f633ce428a4ab32ba2a5f2bbc32bb2c 257 PIRSF PIRSF005624 24 255 3.9E-89 T 12-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 AFE_1007 7031445d7464de63bcaba7e467ce531d 209 Pfam PF01464 Transglycosylase SLT domain 92 189 3.4E-14 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 AFE_1007 7031445d7464de63bcaba7e467ce531d 209 SUPERFAMILY SSF53955 74 207 4.88E-26 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFE_1007 7031445d7464de63bcaba7e467ce531d 209 Gene3D G3DSA:1.10.530.10 81 209 1.6E-27 T 12-10-2018 AFE_0598 72c3c5f1843bd9af29e63efb48ed0673 158 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 150 20.081 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFE_0598 72c3c5f1843bd9af29e63efb48ed0673 158 SUPERFAMILY SSF55486 36 155 7.87E-37 T 12-10-2018 AFE_0598 72c3c5f1843bd9af29e63efb48ed0673 158 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 41 147 7.0E-30 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFE_0598 72c3c5f1843bd9af29e63efb48ed0673 158 Gene3D G3DSA:3.40.390.30 6 157 1.8E-41 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 AFE_0598 72c3c5f1843bd9af29e63efb48ed0673 158 Pfam PF02130 Uncharacterized protein family UPF0054 35 145 4.2E-32 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFE_0598 72c3c5f1843bd9af29e63efb48ed0673 158 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 116 126 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site AFE_2613 ddbd9a2d60cf489598bbab6cffc27699 172 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 77 4.9E-29 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFE_2613 ddbd9a2d60cf489598bbab6cffc27699 172 SUPERFAMILY SSF55200 85 172 1.01E-32 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 AFE_2613 ddbd9a2d60cf489598bbab6cffc27699 172 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 172 2.3E-65 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFE_2613 ddbd9a2d60cf489598bbab6cffc27699 172 ProSitePatterns PS00938 Initiation factor 3 signature. 60 73 - T 12-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 AFE_2613 ddbd9a2d60cf489598bbab6cffc27699 172 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 172 30.702 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFE_2613 ddbd9a2d60cf489598bbab6cffc27699 172 Gene3D G3DSA:3.30.110.10 78 172 6.5E-37 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 AFE_2613 ddbd9a2d60cf489598bbab6cffc27699 172 SUPERFAMILY SSF54364 8 80 3.14E-27 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFE_2613 ddbd9a2d60cf489598bbab6cffc27699 172 Gene3D G3DSA:3.10.20.80 3 77 1.2E-30 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFE_2613 ddbd9a2d60cf489598bbab6cffc27699 172 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 169 4.2E-37 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 AFE_1672 8575fe1e4c043fdd3eae143e1aab4204 345 SUPERFAMILY SSF51556 3 343 6.38E-145 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFE_1672 8575fe1e4c043fdd3eae143e1aab4204 345 ProSitePatterns PS00483 Dihydroorotase signature 2. 246 257 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_1672 8575fe1e4c043fdd3eae143e1aab4204 345 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 5 343 8.4E-139 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_1672 8575fe1e4c043fdd3eae143e1aab4204 345 ProSitePatterns PS00482 Dihydroorotase signature 1. 12 20 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_1672 8575fe1e4c043fdd3eae143e1aab4204 345 Pfam PF01979 Amidohydrolase family 12 306 6.3E-17 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFE_1672 8575fe1e4c043fdd3eae143e1aab4204 345 PIRSF PIRSF001237 1 345 1.6E-142 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_1672 8575fe1e4c043fdd3eae143e1aab4204 345 Hamap MF_00219 Dihydroorotase [pyrC]. 3 344 46.679 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_1672 8575fe1e4c043fdd3eae143e1aab4204 345 Gene3D G3DSA:3.20.20.140 4 344 6.8E-110 T 12-10-2018 AFE_3281 72a89b386cceae9d23eba4c21bb9101f 158 SUPERFAMILY SSF53163 3 154 5.23E-36 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFE_3281 72a89b386cceae9d23eba4c21bb9101f 158 PRINTS PR00446 Hydrogen uptake protein signature 4 16 1.1E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_3281 72a89b386cceae9d23eba4c21bb9101f 158 PRINTS PR00446 Hydrogen uptake protein signature 16 27 1.1E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_3281 72a89b386cceae9d23eba4c21bb9101f 158 PRINTS PR00446 Hydrogen uptake protein signature 56 66 1.1E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_3281 72a89b386cceae9d23eba4c21bb9101f 158 PRINTS PR00446 Hydrogen uptake protein signature 35 52 1.1E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_3281 72a89b386cceae9d23eba4c21bb9101f 158 PRINTS PR00446 Hydrogen uptake protein signature 67 83 1.1E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_3281 72a89b386cceae9d23eba4c21bb9101f 158 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 148 7.7E-38 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_3281 72a89b386cceae9d23eba4c21bb9101f 158 Pfam PF01750 Hydrogenase maturation protease 21 142 1.4E-17 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_3281 72a89b386cceae9d23eba4c21bb9101f 158 Gene3D G3DSA:3.40.50.1450 3 157 2.2E-37 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFE_1487 0ed5573ce29254eb6e3383a8b7ff0c5e 244 SUPERFAMILY SSF74653 158 238 7.32E-24 T 12-10-2018 AFE_1487 0ed5573ce29254eb6e3383a8b7ff0c5e 244 PRINTS PR01217 Proline rich extensin signature 131 156 1.8E-10 T 12-10-2018 AFE_1487 0ed5573ce29254eb6e3383a8b7ff0c5e 244 PRINTS PR01217 Proline rich extensin signature 37 58 1.8E-10 T 12-10-2018 AFE_1487 0ed5573ce29254eb6e3383a8b7ff0c5e 244 PRINTS PR01217 Proline rich extensin signature 1 13 1.8E-10 T 12-10-2018 AFE_1487 0ed5573ce29254eb6e3383a8b7ff0c5e 244 PRINTS PR01217 Proline rich extensin signature 64 80 1.8E-10 T 12-10-2018 AFE_1487 0ed5573ce29254eb6e3383a8b7ff0c5e 244 PRINTS PR01217 Proline rich extensin signature 84 101 1.8E-10 T 12-10-2018 AFE_1487 0ed5573ce29254eb6e3383a8b7ff0c5e 244 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 164 241 3.0E-21 T 12-10-2018 IPR006260 TonB/TolA, C-terminal AFE_1487 0ed5573ce29254eb6e3383a8b7ff0c5e 244 Gene3D G3DSA:3.30.1150.10 143 241 6.8E-28 T 12-10-2018 AFE_1487 0ed5573ce29254eb6e3383a8b7ff0c5e 244 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 162 240 1.6E-24 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 AFE_2756 b97edd3fecb45771f4b1ead89027244d 659 Gene3D G3DSA:3.40.50.300 47 173 6.9E-6 T 12-10-2018 AFE_2756 b97edd3fecb45771f4b1ead89027244d 659 Pfam PF00350 Dynamin family 65 285 4.2E-15 T 12-10-2018 IPR022812 Dynamin superfamily AFE_2756 b97edd3fecb45771f4b1ead89027244d 659 Gene3D G3DSA:3.40.50.300 206 370 2.4E-15 T 12-10-2018 AFE_2756 b97edd3fecb45771f4b1ead89027244d 659 SUPERFAMILY SSF52540 56 351 7.42E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 Gene3D G3DSA:1.20.200.10 136 403 2.1E-113 T 12-10-2018 AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 1 457 1.8E-213 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 Pfam PF00206 Lyase 11 339 1.9E-100 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 Hamap MF_00743 Fumarate hydratase class II [fumC]. 1 457 84.593 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 SUPERFAMILY SSF48557 1 456 6.6E-149 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 Gene3D G3DSA:1.10.40.30 405 456 6.9E-22 T 12-10-2018 AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 Gene3D G3DSA:1.10.275.10 2 135 5.8E-54 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 PRINTS PR00149 Fumarate lyase superfamily signature 314 330 8.4E-33 T 12-10-2018 IPR000362 Fumarate lyase family AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 8.4E-33 T 12-10-2018 IPR000362 Fumarate lyase family AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 PRINTS PR00149 Fumarate lyase superfamily signature 268 295 8.4E-33 T 12-10-2018 IPR000362 Fumarate lyase family AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 8.4E-33 T 12-10-2018 IPR000362 Fumarate lyase family AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 Pfam PF10415 Fumarase C C-terminus 405 457 8.5E-21 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFE_2673 24eff609d1f43b69d671df4864e3a74a 457 ProSitePatterns PS00163 Fumarate lyases signature. 314 323 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFE_3015 5a25887dab8e5e1568bf9de6a56e130d 369 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 5 263 4.8E-95 T 12-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 AFE_3015 5a25887dab8e5e1568bf9de6a56e130d 369 SUPERFAMILY SSF48150 4 220 8.32E-66 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFE_3015 5a25887dab8e5e1568bf9de6a56e130d 369 Gene3D G3DSA:1.10.340.30 19 130 9.2E-78 T 12-10-2018 AFE_3015 5a25887dab8e5e1568bf9de6a56e130d 369 SUPERFAMILY SSF55811 225 365 1.23E-21 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFE_3015 5a25887dab8e5e1568bf9de6a56e130d 369 Gene3D G3DSA:1.10.1670.10 8 208 9.2E-78 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFE_3015 5a25887dab8e5e1568bf9de6a56e130d 369 Gene3D G3DSA:3.90.79.10 230 367 6.3E-17 T 12-10-2018 AFE_3015 5a25887dab8e5e1568bf9de6a56e130d 369 Pfam PF14815 NUDIX domain 232 363 1.3E-21 T 12-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFE_3015 5a25887dab8e5e1568bf9de6a56e130d 369 SMART SM00478 37 187 1.1E-31 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFE_3015 5a25887dab8e5e1568bf9de6a56e130d 369 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 163 6.0E-14 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 Gene3D G3DSA:3.40.50.300 125 303 3.4E-60 T 12-10-2018 AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 Pfam PF13384 Homeodomain-like domain 414 435 5.4E-6 T 12-10-2018 AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 SUPERFAMILY SSF46689 346 435 8.19E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 SUPERFAMILY SSF52540 133 376 1.03E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 Gene3D G3DSA:1.10.8.60 304 382 8.7E-18 T 12-10-2018 AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 SUPERFAMILY SSF55785 10 111 1.08E-12 T 12-10-2018 IPR035965 PAS domain superfamily AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 Gene3D G3DSA:3.30.450.20 9 124 1.9E-9 T 12-10-2018 AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 345 354 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 Pfam PF08448 PAS fold 17 109 4.9E-9 T 12-10-2018 IPR013656 PAS fold-4 AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 SMART SM00382 153 296 1.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2597 e0b0d08dfe3c33e50a205738e9af8548 439 Pfam PF00158 Sigma-54 interaction domain 133 299 1.5E-61 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_0902 2b7d3332ac63cfafe2dee9deb3d00fa5 226 Pfam PF02224 Cytidylate kinase 7 210 1.7E-67 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFE_0902 2b7d3332ac63cfafe2dee9deb3d00fa5 226 SUPERFAMILY SSF52540 5 221 7.45E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0902 2b7d3332ac63cfafe2dee9deb3d00fa5 226 Gene3D G3DSA:3.40.50.300 2 224 1.4E-73 T 12-10-2018 AFE_0902 2b7d3332ac63cfafe2dee9deb3d00fa5 226 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 31.863 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFE_0902 2b7d3332ac63cfafe2dee9deb3d00fa5 226 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 210 2.8E-70 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFE_1659 e36f11e6f3b2e988ff2a8024a031837d 342 Gene3D G3DSA:3.30.450.20 11 165 2.1E-5 T 12-10-2018 AFE_1659 e36f11e6f3b2e988ff2a8024a031837d 342 SUPERFAMILY SSF103190 56 107 5.1E-6 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily AFE_3110 16ad35332ffb4b49a26ac49d0baf9b0a 402 SUPERFAMILY SSF81342 12 267 3.01E-79 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFE_3110 16ad35332ffb4b49a26ac49d0baf9b0a 402 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 278 377 2.3E-29 T 12-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFE_3110 16ad35332ffb4b49a26ac49d0baf9b0a 402 Pfam PF00033 Cytochrome b/b6/petB 23 211 4.0E-58 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFE_3110 16ad35332ffb4b49a26ac49d0baf9b0a 402 Gene3D G3DSA:1.20.810.10 1 402 5.2E-129 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 AFE_3110 16ad35332ffb4b49a26ac49d0baf9b0a 402 SUPERFAMILY SSF81648 204 369 8.5E-40 T 12-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFE_3110 16ad35332ffb4b49a26ac49d0baf9b0a 402 PIRSF PIRSF038885 1 402 3.0E-133 T 12-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 SUPERFAMILY SSF50249 609 686 3.51E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 SUPERFAMILY SSF55666 446 542 1.54E-28 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 PIRSF PIRSF005499 1 690 2.2E-298 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 316 4.3E-13 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 SUPERFAMILY SSF54211 287 484 9.11E-51 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Pfam PF03725 3' exoribonuclease family, domain 2 455 523 1.1E-6 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Pfam PF03725 3' exoribonuclease family, domain 2 144 206 1.2E-13 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 8.5E-23 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Pfam PF01138 3' exoribonuclease family, domain 1 320 452 5.3E-25 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Gene3D G3DSA:3.30.230.70 230 545 1.3E-113 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Pfam PF00013 KH domain 552 609 6.5E-9 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 8 687 0.0 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Gene3D G3DSA:2.40.50.140 617 690 5.1E-29 T 12-10-2018 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 SUPERFAMILY SSF55666 142 233 6.03E-30 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 SMART SM00316 616 686 1.4E-25 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 SUPERFAMILY SSF54211 2 141 1.32E-52 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 SMART SM00322 548 612 1.6E-11 T 12-10-2018 IPR004087 K Homology domain GO:0003676 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 1 689 30.964 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Gene3D G3DSA:3.30.1370.10 546 616 3.1E-19 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Pfam PF00575 S1 RNA binding domain 615 686 4.1E-20 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 Gene3D G3DSA:3.30.230.70 1 226 5.3E-86 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_0395 07d1295ff567f0eb6b4740dca6becc07 690 SUPERFAMILY SSF54791 550 635 5.69E-23 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFE_1908 c532af7a94a60530954360317bd5c003 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_1908 c532af7a94a60530954360317bd5c003 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.9E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1908 c532af7a94a60530954360317bd5c003 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.9E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1908 c532af7a94a60530954360317bd5c003 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.9E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1908 c532af7a94a60530954360317bd5c003 249 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 10 246 3.0E-97 T 12-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFE_1908 c532af7a94a60530954360317bd5c003 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 220 2.6E-7 T 12-10-2018 AFE_1908 c532af7a94a60530954360317bd5c003 249 SUPERFAMILY SSF51735 6 248 6.84E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1908 c532af7a94a60530954360317bd5c003 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.5E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1908 c532af7a94a60530954360317bd5c003 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.5E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1908 c532af7a94a60530954360317bd5c003 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.5E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1908 c532af7a94a60530954360317bd5c003 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.5E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1908 c532af7a94a60530954360317bd5c003 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.5E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1908 c532af7a94a60530954360317bd5c003 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.5E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1908 c532af7a94a60530954360317bd5c003 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 2.0E-62 T 12-10-2018 AFE_1908 c532af7a94a60530954360317bd5c003 249 Gene3D G3DSA:3.40.50.720 2 248 3.6E-82 T 12-10-2018 AFE_0753 20d27fbb968c7759e58f92a0e87c5961 1150 Gene3D G3DSA:3.40.50.300 1 279 8.4E-46 T 12-10-2018 AFE_0753 20d27fbb968c7759e58f92a0e87c5961 1150 Gene3D G3DSA:3.40.50.300 921 1148 8.0E-44 T 12-10-2018 AFE_0753 20d27fbb968c7759e58f92a0e87c5961 1150 SUPERFAMILY SSF75553 464 624 6.93E-7 T 12-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFE_0753 20d27fbb968c7759e58f92a0e87c5961 1150 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1137 21.096 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFE_0753 20d27fbb968c7759e58f92a0e87c5961 1150 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1135 0.0 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFE_0753 20d27fbb968c7759e58f92a0e87c5961 1150 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1128 3.7E-64 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AFE_0753 20d27fbb968c7759e58f92a0e87c5961 1150 PIRSF PIRSF005719 565 1144 8.2E-114 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein AFE_0753 20d27fbb968c7759e58f92a0e87c5961 1150 PIRSF PIRSF005719 1 549 2.0E-110 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein AFE_0753 20d27fbb968c7759e58f92a0e87c5961 1150 SUPERFAMILY SSF90257 658 770 4.71E-5 T 12-10-2018 AFE_0753 20d27fbb968c7759e58f92a0e87c5961 1150 SUPERFAMILY SSF52540 1 1136 4.74E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0234 84611a4895b9bc20399b9e237e9d90bf 265 Pfam PF00535 Glycosyl transferase family 2 17 148 5.5E-16 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFE_0234 84611a4895b9bc20399b9e237e9d90bf 265 Gene3D G3DSA:3.90.550.10 10 237 1.2E-20 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0234 84611a4895b9bc20399b9e237e9d90bf 265 SUPERFAMILY SSF53448 16 158 1.2E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2655 237f859927a67ef8589e69399f55a0e5 128 Pfam PF01850 PIN domain 3 118 4.5E-11 T 12-10-2018 IPR002716 PIN domain AFE_2655 237f859927a67ef8589e69399f55a0e5 128 SUPERFAMILY SSF88723 1 126 1.37E-27 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_2655 237f859927a67ef8589e69399f55a0e5 128 Gene3D G3DSA:3.40.50.1010 1 126 4.9E-28 T 12-10-2018 AFE_1391 ad93728f9a9c6ce051c4a612e63a4544 321 Gene3D G3DSA:2.40.30.160 189 298 9.7E-29 T 12-10-2018 AFE_1391 ad93728f9a9c6ce051c4a612e63a4544 321 PIRSF PIRSF006487 10 296 1.1E-14 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AFE_1391 ad93728f9a9c6ce051c4a612e63a4544 321 Pfam PF01571 Aminomethyltransferase folate-binding domain 14 209 2.9E-14 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain AFE_1391 ad93728f9a9c6ce051c4a612e63a4544 321 Gene3D G3DSA:3.30.70.1400 15 102 1.5E-27 T 12-10-2018 AFE_1391 ad93728f9a9c6ce051c4a612e63a4544 321 Gene3D G3DSA:3.30.70.1630 14 185 1.5E-27 T 12-10-2018 AFE_1391 ad93728f9a9c6ce051c4a612e63a4544 321 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 179 244 2.2E-26 T 12-10-2018 IPR017703 YgfZ/GcvT conserved site AFE_1391 ad93728f9a9c6ce051c4a612e63a4544 321 SUPERFAMILY SSF103025 12 235 2.2E-53 T 12-10-2018 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 SMART SM00896 705 798 2.0E-29 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 SMART SM00874 414 482 1.3E-26 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Pfam PF03483 B3/4 domain 225 394 2.1E-52 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 SMART SM00873 225 396 5.4E-61 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Pfam PF03484 tRNA synthetase B5 domain 418 482 1.7E-16 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Pfam PF03147 Ferredoxin-fold anticodon binding domain 705 798 4.8E-21 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 SUPERFAMILY SSF56037 216 397 1.05E-54 T 12-10-2018 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Gene3D G3DSA:3.30.930.10 504 693 2.0E-51 T 12-10-2018 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 SUPERFAMILY SSF54991 701 798 1.57E-23 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 792 39.474 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 SUPERFAMILY SSF46955 414 486 7.6E-17 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Gene3D G3DSA:3.30.56.10 412 486 1.8E-22 T 12-10-2018 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Gene3D G3DSA:3.30.56.10 7 179 8.7E-63 T 12-10-2018 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Gene3D G3DSA:2.40.50.140 39 154 8.7E-63 T 12-10-2018 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 SUPERFAMILY SSF50249 35 191 2.94E-42 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Gene3D G3DSA:3.30.70.380 706 799 7.7E-21 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 798 4.8E-218 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 SUPERFAMILY SSF55681 478 692 6.46E-47 T 12-10-2018 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Gene3D G3DSA:3.50.40.10 215 402 4.4E-58 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 AFE_2609 b6bc79432394ccf8154cddae19fcfc7e 799 Pfam PF01588 Putative tRNA binding domain 45 145 1.9E-21 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1016 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 Pfam PF01336 OB-fold nucleic acid binding domain 979 1050 1.7E-6 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 Gene3D G3DSA:3.20.20.140 1 268 3.2E-94 T 12-10-2018 AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 290 727 1.5E-174 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 SUPERFAMILY SSF89550 6 262 6.93E-26 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 Gene3D G3DSA:2.40.50.140 967 1060 2.7E-6 T 12-10-2018 AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 Gene3D G3DSA:1.10.150.870 755 877 4.7E-5 T 12-10-2018 AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 Gene3D G3DSA:1.10.10.1600 429 506 1.1E-29 T 12-10-2018 AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 SMART SM00481 7 74 1.8E-28 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 Pfam PF14579 Helix-hairpin-helix motif 800 888 3.8E-24 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_1461 069725ecefec5c3efbb48a75163f9da3 1166 Pfam PF02811 PHP domain 8 171 1.6E-47 T 12-10-2018 IPR004013 PHP domain GO:0003824 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 180 200 5.0E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 229 244 5.0E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 Pfam PF01926 50S ribosome-binding GTPase 5 120 4.5E-26 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 Pfam PF01926 50S ribosome-binding GTPase 179 297 4.0E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 Gene3D G3DSA:3.40.50.300 173 347 1.4E-49 T 12-10-2018 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 Gene3D G3DSA:3.30.300.20 353 435 1.2E-21 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 153 1.1E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 177 343 1.3E-24 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 355 433 3.7E-25 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 Hamap MF_00195 GTPase Der [der]. 2 436 37.94 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 433 7.8E-170 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 Gene3D G3DSA:3.40.50.300 2 162 1.3E-43 T 12-10-2018 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 SUPERFAMILY SSF52540 5 164 2.33E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 PIRSF PIRSF006485 1 441 2.5E-167 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFE_1937 4b1af81d23a49c32987b267b2a0fbe50 449 SUPERFAMILY SSF52540 138 439 4.97E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3045 28e5e3ec48309795c7468bd7b04b4314 242 Pfam PF00977 Histidine biosynthesis protein 3 231 7.0E-75 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 AFE_3045 28e5e3ec48309795c7468bd7b04b4314 242 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 235 2.2E-75 T 12-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AFE_3045 28e5e3ec48309795c7468bd7b04b4314 242 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 239 34.795 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AFE_3045 28e5e3ec48309795c7468bd7b04b4314 242 Gene3D G3DSA:3.20.20.70 1 241 2.3E-83 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_3045 28e5e3ec48309795c7468bd7b04b4314 242 SUPERFAMILY SSF51366 1 237 9.42E-73 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 30 857 22.86 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Pfam PF00488 MutS domain V 629 812 1.3E-79 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Pfam PF05188 MutS domain II 153 273 7.1E-10 T 12-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Gene3D G3DSA:3.40.50.300 588 850 4.4E-99 T 12-10-2018 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 SUPERFAMILY SSF55271 27 138 1.44E-40 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Gene3D G3DSA:1.10.1420.10 286 577 1.1E-86 T 12-10-2018 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 30 862 6.1E-303 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 SUPERFAMILY SSF53150 137 285 6.54E-22 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Pfam PF01624 MutS domain I 31 141 3.7E-40 T 12-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 PIRSF PIRSF037677 21 202 6.7E-24 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 PIRSF PIRSF037677 238 843 1.9E-121 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 SUPERFAMILY SSF48334 287 582 9.68E-75 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Pfam PF05192 MutS domain III 290 577 4.6E-35 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Pfam PF05190 MutS family domain IV 447 536 1.1E-25 T 12-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 706 722 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Gene3D G3DSA:1.10.1420.10 405 521 1.1E-86 T 12-10-2018 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Gene3D G3DSA:3.30.420.110 152 280 1.0E-19 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 Gene3D G3DSA:3.40.1170.10 23 144 3.6E-49 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 SUPERFAMILY SSF52540 585 813 3.67E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 SMART SM00534 625 809 4.9E-118 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFE_1760 a3c43549638e8319a9c33af57ce59e1b 870 SMART SM00533 302 609 2.7E-84 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AFE_0744 b48a1ed509dbedf48d6d6ae24fac36e2 512 SUPERFAMILY SSF48334 61 274 4.19E-7 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily AFE_0744 b48a1ed509dbedf48d6d6ae24fac36e2 512 SMART SM00533 11 302 0.0069 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AFE_0744 b48a1ed509dbedf48d6d6ae24fac36e2 512 Pfam PF00488 MutS domain V 326 509 1.6E-32 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFE_0744 b48a1ed509dbedf48d6d6ae24fac36e2 512 Gene3D G3DSA:3.40.50.300 282 512 1.3E-61 T 12-10-2018 AFE_0744 b48a1ed509dbedf48d6d6ae24fac36e2 512 SMART SM00534 322 507 4.8E-54 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFE_0744 b48a1ed509dbedf48d6d6ae24fac36e2 512 SUPERFAMILY SSF52540 282 510 5.94E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1388 31fc8f9c66ae45aec2661253575dff45 577 Pfam PF00005 ABC transporter 353 502 2.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_1388 31fc8f9c66ae45aec2661253575dff45 577 SUPERFAMILY SSF90123 4 317 1.7E-54 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_1388 31fc8f9c66ae45aec2661253575dff45 577 Gene3D G3DSA:3.40.50.300 328 576 3.8E-84 T 12-10-2018 AFE_1388 31fc8f9c66ae45aec2661253575dff45 577 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 13 544 2.3E-190 T 12-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 AFE_1388 31fc8f9c66ae45aec2661253575dff45 577 Gene3D G3DSA:1.20.1560.10 3 319 1.3E-50 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_1388 31fc8f9c66ae45aec2661253575dff45 577 SMART SM00382 361 548 3.0E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1388 31fc8f9c66ae45aec2661253575dff45 577 Pfam PF00664 ABC transporter transmembrane region 18 265 3.0E-28 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFE_1388 31fc8f9c66ae45aec2661253575dff45 577 SUPERFAMILY SSF52540 329 570 2.07E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1388 31fc8f9c66ae45aec2661253575dff45 577 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2272 bbe70453d1423e76b514d5a1a5c9ab90 170 Pfam PF12092 Protein of unknown function (DUF3568) 10 127 7.4E-17 T 12-10-2018 IPR021952 Protein of unknown function DUF3568 AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 Gene3D G3DSA:3.40.140.20 214 366 7.0E-58 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 Pfam PF02142 MGS-like domain 19 134 1.1E-24 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 SUPERFAMILY SSF52335 7 198 3.92E-68 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 523 44.506 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 PIRSF PIRSF000414 4 523 1.9E-208 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 Pfam PF01808 AICARFT/IMPCHase bienzyme 139 454 3.5E-115 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 Gene3D G3DSA:3.40.50.1380 4 201 9.9E-85 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 SUPERFAMILY SSF53927 217 523 3.11E-125 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 SMART SM00851 19 134 4.1E-53 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 SMART SM00798 139 455 2.9E-186 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 Gene3D G3DSA:3.40.140.20 386 523 3.8E-57 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_2260 5562567c3f1756a6bc59bf0d5f046045 524 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 9 523 1.8E-210 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFE_0367 95de263bf582d9dbe7836e68883b7282 247 ProSitePatterns PS00195 Glutaredoxin active site. 176 192 - T 12-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 AFE_0367 95de263bf582d9dbe7836e68883b7282 247 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 165 244 5.9E-33 T 12-10-2018 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 AFE_0367 95de263bf582d9dbe7836e68883b7282 247 SUPERFAMILY SSF52833 6 244 8.79E-42 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0367 95de263bf582d9dbe7836e68883b7282 247 Gene3D G3DSA:3.40.30.10 173 245 5.9E-21 T 12-10-2018 AFE_0367 95de263bf582d9dbe7836e68883b7282 247 Pfam PF08534 Redoxin 8 161 8.7E-32 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AFE_0367 95de263bf582d9dbe7836e68883b7282 247 Gene3D G3DSA:3.40.30.10 6 166 4.6E-61 T 12-10-2018 AFE_0367 95de263bf582d9dbe7836e68883b7282 247 PRINTS PR00160 Glutaredoxin signature 217 230 4.5E-14 T 12-10-2018 IPR014025 Glutaredoxin subgroup AFE_0367 95de263bf582d9dbe7836e68883b7282 247 PRINTS PR00160 Glutaredoxin signature 231 244 4.5E-14 T 12-10-2018 IPR014025 Glutaredoxin subgroup AFE_0367 95de263bf582d9dbe7836e68883b7282 247 PRINTS PR00160 Glutaredoxin signature 174 192 4.5E-14 T 12-10-2018 IPR014025 Glutaredoxin subgroup AFE_0367 95de263bf582d9dbe7836e68883b7282 247 Pfam PF00462 Glutaredoxin 174 234 3.9E-17 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFE_1296 369c8b19f52f68e011b3b44f99565f81 320 SUPERFAMILY SSF53850 89 300 1.31E-43 T 12-10-2018 AFE_1296 369c8b19f52f68e011b3b44f99565f81 320 Gene3D G3DSA:3.40.190.10 93 303 1.6E-95 T 12-10-2018 AFE_1296 369c8b19f52f68e011b3b44f99565f81 320 Gene3D G3DSA:1.10.10.10 1 86 8.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1296 369c8b19f52f68e011b3b44f99565f81 320 SUPERFAMILY SSF46785 1 88 2.72E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1296 369c8b19f52f68e011b3b44f99565f81 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 4.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_1296 369c8b19f52f68e011b3b44f99565f81 320 Pfam PF03466 LysR substrate binding domain 88 291 4.0E-45 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_1296 369c8b19f52f68e011b3b44f99565f81 320 Gene3D G3DSA:3.40.190.10 167 267 1.6E-95 T 12-10-2018 AFE_1296 369c8b19f52f68e011b3b44f99565f81 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.5E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_1296 369c8b19f52f68e011b3b44f99565f81 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.5E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_1296 369c8b19f52f68e011b3b44f99565f81 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.5E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0377 a58aca3dca0fbeeec1ce331946e3752d 230 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 56 220 8.0E-45 T 12-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like AFE_0377 a58aca3dca0fbeeec1ce331946e3752d 230 Gene3D G3DSA:2.50.20.10 44 230 4.5E-53 T 12-10-2018 AFE_0377 a58aca3dca0fbeeec1ce331946e3752d 230 SUPERFAMILY SSF89392 49 229 2.28E-47 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFE_0377 a58aca3dca0fbeeec1ce331946e3752d 230 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 31 230 29.347 T 12-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 AFE_0377 a58aca3dca0fbeeec1ce331946e3752d 230 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 33 228 4.4E-27 T 12-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 AFE_2360 3184d4de22ecce3636b5f273ee09b08f 217 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 16 215 8.1E-52 T 12-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 AFE_2360 3184d4de22ecce3636b5f273ee09b08f 217 Pfam PF03006 Haemolysin-III related 14 208 9.2E-34 T 12-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 AFE_0374 cedc71573f1378647b55d44fdd557873 192 Pfam PF01713 Smr domain 106 186 1.1E-21 T 12-10-2018 IPR002625 Smr domain AFE_0374 cedc71573f1378647b55d44fdd557873 192 SMART SM00463 103 187 2.4E-12 T 12-10-2018 IPR002625 Smr domain AFE_0374 cedc71573f1378647b55d44fdd557873 192 Gene3D G3DSA:3.30.1370.110 67 191 3.4E-37 T 12-10-2018 AFE_0374 cedc71573f1378647b55d44fdd557873 192 SUPERFAMILY SSF160443 105 186 1.83E-18 T 12-10-2018 IPR036063 Smr domain superfamily AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 303 310 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 PIRSF PIRSF001500 1 358 3.2E-121 T 12-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 Gene3D G3DSA:3.40.190.10 94 263 8.3E-55 T 12-10-2018 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 SUPERFAMILY SSF55021 260 355 3.52E-23 T 12-10-2018 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 Pfam PF01842 ACT domain 277 327 3.9E-8 T 12-10-2018 IPR002912 ACT domain AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 Gene3D G3DSA:3.30.70.260 267 357 1.0E-26 T 12-10-2018 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 Gene3D G3DSA:1.20.59.10 6 90 9.2E-27 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 SUPERFAMILY SSF53850 91 273 8.25E-54 T 12-10-2018 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 SUPERFAMILY SSF48600 5 93 3.11E-18 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 Gene3D G3DSA:3.40.190.10 172 255 8.3E-55 T 12-10-2018 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 SMART SM00830 10 90 9.7E-26 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 241 263 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 Pfam PF00800 Prephenate dehydratase 92 265 1.5E-55 T 12-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 Pfam PF01817 Chorismate mutase type II 10 88 4.5E-20 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFE_0897 2426d807bc3d2008f051c9dc5b8231cb 358 TIGRFAM TIGR01807 CM_P2: chorismate mutase 6 80 3.6E-23 T 12-10-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 AFE_2278 3369a5f48b8b071228daff6bf5b28514 158 Pfam PF06754 Phosphonate metabolism protein PhnG 16 153 5.6E-43 T 12-10-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFE_2278 3369a5f48b8b071228daff6bf5b28514 158 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 15 155 6.4E-49 T 12-10-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 Hamap MF_00020 Acetate kinase [ackA]. 1 390 144.108 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 Pfam PF00871 Acetokinase family 7 381 2.7E-106 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 SUPERFAMILY SSF53067 158 387 1.2E-72 T 12-10-2018 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 PRINTS PR00471 Acetate kinase family signature 368 380 2.4E-39 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 PRINTS PR00471 Acetate kinase family signature 316 332 2.4E-39 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 PRINTS PR00471 Acetate kinase family signature 198 219 2.4E-39 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 PRINTS PR00471 Acetate kinase family signature 7 18 2.4E-39 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 PRINTS PR00471 Acetate kinase family signature 173 186 2.4E-39 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 PRINTS PR00471 Acetate kinase family signature 294 307 2.4E-39 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 Gene3D G3DSA:3.30.420.40 194 391 2.4E-67 T 12-10-2018 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 PIRSF PIRSF000722 3 391 5.9E-125 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 7 18 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 Gene3D G3DSA:3.30.420.40 1 193 1.1E-56 T 12-10-2018 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 TIGRFAM TIGR00016 ackA: acetate kinase 5 387 9.4E-110 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 SUPERFAMILY SSF53067 5 193 9.71E-52 T 12-10-2018 AFE_1810 fa3cc27033cfd96728e37d07094da0c1 394 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 198 215 - T 12-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFE_0806 d4b5601cd909e12b47360a8cdc0a4868 802 Gene3D G3DSA:1.10.1400.10 571 685 2.1E-101 T 12-10-2018 AFE_0806 d4b5601cd909e12b47360a8cdc0a4868 802 Gene3D G3DSA:3.60.20.10 290 776 2.1E-101 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_0806 d4b5601cd909e12b47360a8cdc0a4868 802 PIRSF PIRSF001227 90 370 1.3E-49 T 12-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 AFE_0806 d4b5601cd909e12b47360a8cdc0a4868 802 PIRSF PIRSF001227 391 801 1.9E-55 T 12-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 AFE_0806 d4b5601cd909e12b47360a8cdc0a4868 802 Pfam PF01804 Penicillin amidase 100 789 3.3E-147 T 12-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 AFE_0806 d4b5601cd909e12b47360a8cdc0a4868 802 SUPERFAMILY SSF56235 98 792 1.49E-134 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_0806 d4b5601cd909e12b47360a8cdc0a4868 802 Gene3D G3DSA:1.10.439.10 82 232 4.4E-35 T 12-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 AFE_0806 d4b5601cd909e12b47360a8cdc0a4868 802 Gene3D G3DSA:2.30.120.10 362 423 2.1E-101 T 12-10-2018 AFE_3206 48b7e2f9ff64879bebdb87ce0450e915 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 179 17.159 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3206 48b7e2f9ff64879bebdb87ce0450e915 179 Gene3D G3DSA:1.10.520.20 2 107 8.0E-18 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3206 48b7e2f9ff64879bebdb87ce0450e915 179 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 139 158 - T 12-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3206 48b7e2f9ff64879bebdb87ce0450e915 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 177 6.2E-41 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3206 48b7e2f9ff64879bebdb87ce0450e915 179 SUPERFAMILY SSF47928 4 106 3.14E-18 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3206 48b7e2f9ff64879bebdb87ce0450e915 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 177 7.8E-32 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3206 48b7e2f9ff64879bebdb87ce0450e915 179 PRINTS PR00125 ATP synthase delta subunit signature 7 26 3.5E-17 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3206 48b7e2f9ff64879bebdb87ce0450e915 179 PRINTS PR00125 ATP synthase delta subunit signature 152 170 3.5E-17 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3206 48b7e2f9ff64879bebdb87ce0450e915 179 PRINTS PR00125 ATP synthase delta subunit signature 137 152 3.5E-17 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3206 48b7e2f9ff64879bebdb87ce0450e915 179 PRINTS PR00125 ATP synthase delta subunit signature 75 86 3.5E-17 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_2470 1636ad638b8aeb3e8602bdae32095778 545 Pfam PF13007 Transposase C of IS166 homeodomain 54 147 3.2E-18 T 12-10-2018 IPR024463 Transposase TnpC, homeodomain AFE_2470 1636ad638b8aeb3e8602bdae32095778 545 Pfam PF03050 Transposase IS66 family 211 493 5.1E-99 T 12-10-2018 IPR004291 Transposase, IS66 AFE_2470 1636ad638b8aeb3e8602bdae32095778 545 Pfam PF13005 zinc-finger binding domain of transposase IS66 154 197 3.9E-16 T 12-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFE_2470 1636ad638b8aeb3e8602bdae32095778 545 Pfam PF13817 IS66 C-terminal element 500 537 4.9E-19 T 12-10-2018 IPR039552 Transposase IS66, C-terminal AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 4.7E-69 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.7E-69 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 4.7E-69 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 4.7E-69 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 4.7E-69 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 4.7E-69 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 4.7E-69 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 4.7E-69 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 4.7E-69 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 448 1.5E-33 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PIRSF PIRSF000350 1 446 3.0E-89 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 SUPERFAMILY SSF55424 337 449 7.73E-34 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 8.9E-31 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 8.9E-31 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 8.9E-31 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 8.9E-31 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 8.9E-31 T 12-10-2018 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 317 1.8E-60 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 Gene3D G3DSA:3.50.50.60 143 260 4.7E-111 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 SUPERFAMILY SSF51905 1 364 3.97E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 Gene3D G3DSA:3.30.390.30 337 449 1.8E-45 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 4 449 2.4E-184 T 12-10-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 AFE_0366 7e48e3c7b5886dc0c1203cf2aafc9aaa 449 Gene3D G3DSA:3.50.50.60 5 321 4.7E-111 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 7.4E-26 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 7.4E-26 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 7.4E-26 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 202 7.4E-26 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 PRINTS PR00987 Glutamyl-tRNA synthetase signature 178 188 7.4E-26 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 Gene3D G3DSA:3.40.50.620 1 313 1.6E-136 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 Gene3D G3DSA:1.10.10.350 371 466 1.8E-22 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 SUPERFAMILY SSF52374 3 297 2.06E-114 T 12-10-2018 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 463 32.654 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 461 3.9E-172 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 304 2.1E-106 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 AFE_0422 3ba55bc8daee14702981dd64a9dd4ac4 466 SUPERFAMILY SSF48163 298 462 2.09E-37 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFE_1939 ef27fc3d78e567395373580174828b13 358 Gene3D G3DSA:3.40.190.10 40 345 1.3E-102 T 12-10-2018 AFE_1939 ef27fc3d78e567395373580174828b13 358 SUPERFAMILY SSF53850 37 357 2.85E-81 T 12-10-2018 AFE_1939 ef27fc3d78e567395373580174828b13 358 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 38 357 1.5E-102 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFE_1939 ef27fc3d78e567395373580174828b13 358 Pfam PF12849 PBP superfamily domain 29 324 1.4E-50 T 12-10-2018 IPR024370 PBP domain AFE_1939 ef27fc3d78e567395373580174828b13 358 PIRSF PIRSF002756 5 358 2.4E-84 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFE_1939 ef27fc3d78e567395373580174828b13 358 Gene3D G3DSA:3.40.190.10 112 295 1.3E-102 T 12-10-2018 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 SUPERFAMILY SSF52540 5 268 7.48E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 5 324 7.4E-174 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 SUPERFAMILY SSF54752 269 325 4.58E-22 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 Gene3D G3DSA:3.30.250.10 269 327 2.2E-27 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 SMART SM00382 58 229 1.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 Gene3D G3DSA:3.40.50.300 27 268 1.8E-83 T 12-10-2018 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 Pfam PF00154 recA bacterial DNA recombination protein 7 269 2.7E-147 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 ProSitePatterns PS00321 recA signature. 214 222 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 Hamap MF_00268 Protein RecA [recA]. 5 330 51.969 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 PRINTS PR00142 RecA protein signature 94 123 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 PRINTS PR00142 RecA protein signature 244 273 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 PRINTS PR00142 RecA protein signature 298 315 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 PRINTS PR00142 RecA protein signature 128 157 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 PRINTS PR00142 RecA protein signature 211 239 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFE_0932 96ff7b79d37760bc2fca9ad19e36ed98 345 PRINTS PR00142 RecA protein signature 166 195 1.2E-85 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFE_0326 d87df60cd9010e4968df22904ab6c279 102 Gene3D G3DSA:3.30.70.600 1 102 6.6E-38 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily AFE_0326 d87df60cd9010e4968df22904ab6c279 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0326 d87df60cd9010e4968df22904ab6c279 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.0E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0326 d87df60cd9010e4968df22904ab6c279 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.0E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0326 d87df60cd9010e4968df22904ab6c279 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.0E-20 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0326 d87df60cd9010e4968df22904ab6c279 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.947 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0326 d87df60cd9010e4968df22904ab6c279 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 5 101 1.6E-44 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0326 d87df60cd9010e4968df22904ab6c279 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 2.9E-36 T 12-10-2018 IPR027486 Ribosomal protein S10 domain AFE_0326 d87df60cd9010e4968df22904ab6c279 102 SUPERFAMILY SSF54999 5 102 1.57E-38 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily AFE_0326 d87df60cd9010e4968df22904ab6c279 102 SMART SM01403 7 101 1.6E-56 T 12-10-2018 IPR027486 Ribosomal protein S10 domain AFE_2134 f95528a118a710f75a46f81a270a5dc4 221 SUPERFAMILY SSF159594 37 211 6.54E-33 T 12-10-2018 AFE_2134 f95528a118a710f75a46f81a270a5dc4 221 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 43 204 4.0E-17 T 12-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component AFE_2134 f95528a118a710f75a46f81a270a5dc4 221 Gene3D G3DSA:3.40.50.10610 29 220 4.7E-28 T 12-10-2018 AFE_2332 8094ec74d9d8e04db0ca5f197eed4648 308 Pfam PF03466 LysR substrate binding domain 89 300 1.9E-38 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_2332 8094ec74d9d8e04db0ca5f197eed4648 308 SUPERFAMILY SSF46785 4 88 4.29E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2332 8094ec74d9d8e04db0ca5f197eed4648 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 6.7E-24 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2332 8094ec74d9d8e04db0ca5f197eed4648 308 Gene3D G3DSA:3.40.190.10 97 293 3.0E-57 T 12-10-2018 AFE_2332 8094ec74d9d8e04db0ca5f197eed4648 308 Gene3D G3DSA:1.10.10.10 3 96 8.9E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2332 8094ec74d9d8e04db0ca5f197eed4648 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.1E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2332 8094ec74d9d8e04db0ca5f197eed4648 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.1E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2332 8094ec74d9d8e04db0ca5f197eed4648 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.1E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2332 8094ec74d9d8e04db0ca5f197eed4648 308 SUPERFAMILY SSF53850 90 303 1.38E-36 T 12-10-2018 AFE_2332 8094ec74d9d8e04db0ca5f197eed4648 308 Gene3D G3DSA:3.40.190.10 166 275 3.0E-57 T 12-10-2018 AFE_0068 1b2d934905956c25bda05e6ad575fa7f 229 PIRSF PIRSF006293 5 229 7.9E-73 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFE_0068 1b2d934905956c25bda05e6ad575fa7f 229 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 6 224 51.035 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFE_0068 1b2d934905956c25bda05e6ad575fa7f 229 SUPERFAMILY SSF52402 7 227 1.06E-63 T 12-10-2018 AFE_0068 1b2d934905956c25bda05e6ad575fa7f 229 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 8 211 3.7E-58 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFE_0068 1b2d934905956c25bda05e6ad575fa7f 229 Gene3D G3DSA:3.40.50.620 6 224 4.5E-70 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0068 1b2d934905956c25bda05e6ad575fa7f 229 Pfam PF06508 Queuosine biosynthesis protein QueC 8 218 9.4E-73 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 Pfam PF13541 Subunit ChlI of Mg-chelatase 343 424 7.3E-11 T 12-10-2018 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 PRINTS PR01874 DNA repair protein radA signature 119 136 1.1E-94 T 12-10-2018 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 PRINTS PR01874 DNA repair protein radA signature 169 193 1.1E-94 T 12-10-2018 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 PRINTS PR01874 DNA repair protein radA signature 10 34 1.1E-94 T 12-10-2018 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 PRINTS PR01874 DNA repair protein radA signature 78 106 1.1E-94 T 12-10-2018 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 PRINTS PR01874 DNA repair protein radA signature 208 236 1.1E-94 T 12-10-2018 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 PRINTS PR01874 DNA repair protein radA signature 317 340 1.1E-94 T 12-10-2018 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 PRINTS PR01874 DNA repair protein radA signature 243 269 1.1E-94 T 12-10-2018 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 Pfam PF13481 AAA domain 64 217 1.3E-16 T 12-10-2018 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 SUPERFAMILY SSF52540 65 286 7.41E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 SUPERFAMILY SSF54211 250 449 6.45E-39 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 Gene3D G3DSA:3.40.50.300 65 279 5.6E-38 T 12-10-2018 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 Hamap MF_01498 DNA repair protein RadA [radA]. 21 449 43.447 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 Gene3D G3DSA:3.30.230.10 329 451 1.2E-16 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 SMART SM00382 86 239 8.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2817 f5d19e9e40103d9e7008cf49ab237f08 452 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 444 2.0E-179 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 AFE_1662 4bdb19ab750f394e1366537dc81c2945 546 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 227 248 9.7E-24 T 12-10-2018 AFE_1662 4bdb19ab750f394e1366537dc81c2945 546 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 316 328 9.7E-24 T 12-10-2018 AFE_1662 4bdb19ab750f394e1366537dc81c2945 546 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 249 275 9.7E-24 T 12-10-2018 AFE_1662 4bdb19ab750f394e1366537dc81c2945 546 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 9.7E-24 T 12-10-2018 AFE_1662 4bdb19ab750f394e1366537dc81c2945 546 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 9.7E-24 T 12-10-2018 AFE_1662 4bdb19ab750f394e1366537dc81c2945 546 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 9.7E-24 T 12-10-2018 AFE_1662 4bdb19ab750f394e1366537dc81c2945 546 Pfam PF00361 Proton-conducting membrane transporter 136 375 5.4E-37 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_1662 4bdb19ab750f394e1366537dc81c2945 546 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 76 122 8.2E-7 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_1340 5d0cd49d744f66bcbd9d465e3e168621 820 Gene3D G3DSA:3.40.50.300 533 802 3.0E-60 T 12-10-2018 AFE_1340 5d0cd49d744f66bcbd9d465e3e168621 820 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 593 791 9.7E-34 T 12-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 AFE_1340 5d0cd49d744f66bcbd9d465e3e168621 820 Pfam PF13614 AAA domain 609 728 1.3E-11 T 12-10-2018 IPR025669 AAA domain AFE_1340 5d0cd49d744f66bcbd9d465e3e168621 820 SUPERFAMILY SSF52540 608 783 4.62E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1340 5d0cd49d744f66bcbd9d465e3e168621 820 Pfam PF13807 G-rich domain on putative tyrosine kinase 461 539 8.8E-12 T 12-10-2018 IPR032807 Tyrosine kinase, G-rich domain AFE_1340 5d0cd49d744f66bcbd9d465e3e168621 820 Pfam PF02706 Chain length determinant protein 13 107 2.4E-8 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 Pfam PF00009 Elongation factor Tu GTP binding domain 6 184 4.6E-50 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 SUPERFAMILY SSF50447 169 291 5.52E-26 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 Gene3D G3DSA:3.30.70.870 289 370 2.5E-35 T 12-10-2018 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 Gene3D G3DSA:3.30.70.2570 482 556 4.5E-32 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 Gene3D G3DSA:3.40.50.300 3 188 1.1E-71 T 12-10-2018 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 SUPERFAMILY SSF52540 3 209 2.49E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 Pfam PF03144 Elongation factor Tu domain 2 208 278 6.9E-8 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 177 2.4E-19 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 Gene3D G3DSA:2.40.30.10 189 288 1.3E-28 T 12-10-2018 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 Gene3D G3DSA:3.30.70.3380 371 481 1.6E-40 T 12-10-2018 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 TIGRFAM TIGR01393 lepA: elongation factor 4 6 598 7.4E-293 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 SUPERFAMILY SSF54980 295 373 1.22E-18 T 12-10-2018 IPR035647 EF-G domain III/V-like AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 Hamap MF_00071 Elongation factor 4 [lepA]. 1 600 295.637 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 Pfam PF06421 GTP-binding protein LepA C-terminus 490 596 6.2E-50 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 PRINTS PR00315 GTP-binding elongation factor signature 129 138 4.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 PRINTS PR00315 GTP-binding elongation factor signature 77 87 4.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 PRINTS PR00315 GTP-binding elongation factor signature 52 60 4.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 PRINTS PR00315 GTP-binding elongation factor signature 93 104 4.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 PRINTS PR00315 GTP-binding elongation factor signature 9 22 4.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 SUPERFAMILY SSF54980 402 496 3.55E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 SMART SM00838 401 489 0.0096 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFE_1397 bcf3bf20d049e5908cf8197fda5e8778 600 Pfam PF00679 Elongation factor G C-terminus 402 488 5.7E-21 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like AFE_0432 478a23df96330c2fa8b30231aa85575b 241 SUPERFAMILY SSF64438 2 238 6.41E-81 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic AFE_0432 478a23df96330c2fa8b30231aa85575b 241 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 15 237 8.7E-76 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase AFE_0432 478a23df96330c2fa8b30231aa85575b 241 Gene3D G3DSA:3.60.140.10 1 240 8.9E-91 T 12-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily AFE_0432 478a23df96330c2fa8b30231aa85575b 241 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 21 237 4.7E-59 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase AFE_1799 1f0b9986ae044516cb395754f29afbd2 841 SUPERFAMILY SSF53756 13 714 5.1E-188 T 12-10-2018 AFE_1799 1f0b9986ae044516cb395754f29afbd2 841 Gene3D G3DSA:3.40.50.2000 265 421 3.1E-17 T 12-10-2018 AFE_1799 1f0b9986ae044516cb395754f29afbd2 841 Pfam PF00343 Carbohydrate phosphorylase 270 619 9.2E-24 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFE_1799 1f0b9986ae044516cb395754f29afbd2 841 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 106 709 1.3E-239 T 12-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 AFE_1799 1f0b9986ae044516cb395754f29afbd2 841 Gene3D G3DSA:3.40.50.2000 114 187 6.6E-9 T 12-10-2018 AFE_1799 1f0b9986ae044516cb395754f29afbd2 841 Gene3D G3DSA:3.40.50.2000 422 665 4.8E-38 T 12-10-2018 AFE_1799 1f0b9986ae044516cb395754f29afbd2 841 Pfam PF11897 Protein of unknown function (DUF3417) 12 119 1.0E-30 T 12-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 AFE_1799 1f0b9986ae044516cb395754f29afbd2 841 PIRSF PIRSF000460 4 784 4.9E-243 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFE_1204 64cb080eb22788aca326f4f8eb906d4f 609 Pfam PF15978 Tn7-like transposition protein D 205 544 1.4E-96 T 12-10-2018 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl AFE_1204 64cb080eb22788aca326f4f8eb906d4f 609 Pfam PF06527 TniQ 5 160 2.2E-21 T 12-10-2018 IPR009492 TniQ AFE_2855 edd707c72f33a2b282d6e686c1d328ff 86 Gene3D G3DSA:3.30.1320.10 1 86 3.0E-34 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2855 edd707c72f33a2b282d6e686c1d328ff 86 Pfam PF00886 Ribosomal protein S16 8 66 3.0E-27 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2855 edd707c72f33a2b282d6e686c1d328ff 86 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 76 24.926 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2855 edd707c72f33a2b282d6e686c1d328ff 86 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 78 3.5E-32 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2855 edd707c72f33a2b282d6e686c1d328ff 86 SUPERFAMILY SSF54565 1 80 1.31E-32 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SUPERFAMILY SSF47336 2366 2457 5.89E-17 T 12-10-2018 IPR036736 ACP-like superfamily AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SMART SM00829 1747 2062 1.9E-170 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 535 833 3.1E-85 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SMART SM00823 Phosphopantetheine attachment site 2369 2440 4.8E-18 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SUPERFAMILY SSF51735 2085 2327 3.02E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SMART SM00826 896 1054 1.1E-35 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 251 8.2E-77 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 376 4.3E-39 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Gene3D G3DSA:1.10.1200.10 2361 2445 1.9E-16 T 12-10-2018 IPR036736 ACP-like superfamily AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SMART SM01294 2370 2436 0.0054 T 12-10-2018 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Pfam PF00698 Acyl transferase domain 533 851 2.3E-62 T 12-10-2018 IPR014043 Acyl transferase AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Pfam PF00550 Phosphopantetheine attachment site 2371 2436 2.2E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SUPERFAMILY SSF53901 2 424 1.2E-89 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SMART SM00825 Beta-ketoacyl synthase 6 428 4.0E-177 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SUPERFAMILY SSF51735 1855 2027 5.59E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 380 493 2.6E-18 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2088 2268 7.0E-53 T 12-10-2018 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SUPERFAMILY SSF55048 657 723 9.29E-9 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Pfam PF08659 KR domain 2088 2266 3.8E-61 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 164 180 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Gene3D G3DSA:3.40.47.10 1 441 2.7E-171 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Gene3D G3DSA:3.30.70.3290 445 879 8.9E-125 T 12-10-2018 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Gene3D G3DSA:3.40.366.10 533 836 8.9E-125 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SUPERFAMILY SSF50129 1738 1885 4.25E-28 T 12-10-2018 IPR011032 GroES-like superfamily AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SUPERFAMILY SSF51735 1522 1727 4.72E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Gene3D G3DSA:3.40.50.720 1868 2010 3.9E-116 T 12-10-2018 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Gene3D G3DSA:3.10.129.110 882 1173 4.2E-61 T 12-10-2018 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Gene3D G3DSA:3.90.180.10 1750 2062 3.9E-116 T 12-10-2018 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Gene3D G3DSA:3.40.50.720 2082 2333 1.2E-66 T 12-10-2018 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Pfam PF14765 Polyketide synthase dehydratase 896 1169 1.1E-59 T 12-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 SUPERFAMILY SSF52151 533 817 2.43E-59 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFE_3010 c9fe1f05d271cbff76f48820bc2d802d 2486 Pfam PF00107 Zinc-binding dehydrogenase 1891 2004 1.9E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFE_0463 f1c4add7f1a4f537b5d42c23949c5c1d 267 SUPERFAMILY SSF46946 136 222 3.4E-17 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFE_0463 f1c4add7f1a4f537b5d42c23949c5c1d 267 SUPERFAMILY SSF57716 220 266 7.7E-7 T 12-10-2018 AFE_0463 f1c4add7f1a4f537b5d42c23949c5c1d 267 SUPERFAMILY SSF81624 3 142 1.2E-12 T 12-10-2018 IPR035937 MutM-like, N-terminal AFE_0463 f1c4add7f1a4f537b5d42c23949c5c1d 267 Pfam PF06827 Zinc finger found in FPG and IleRS 242 266 4.0E-6 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFE_0463 f1c4add7f1a4f537b5d42c23949c5c1d 267 SMART SM00898 3 122 8.6E-5 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFE_0463 f1c4add7f1a4f537b5d42c23949c5c1d 267 Gene3D G3DSA:1.10.8.50 137 267 1.5E-29 T 12-10-2018 AFE_0463 f1c4add7f1a4f537b5d42c23949c5c1d 267 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 4.4E-11 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFE_0463 f1c4add7f1a4f537b5d42c23949c5c1d 267 SMART SM01232 137 230 6.6E-19 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFE_0463 f1c4add7f1a4f537b5d42c23949c5c1d 267 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 137 224 3.1E-17 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFE_0463 f1c4add7f1a4f537b5d42c23949c5c1d 267 Gene3D G3DSA:3.20.190.10 2 132 1.1E-10 T 12-10-2018 IPR035937 MutM-like, N-terminal AFE_0802 2dd1bd338dae0fba5562adf9b175b032 453 Pfam PF00501 AMP-binding enzyme 13 288 5.4E-16 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFE_0802 2dd1bd338dae0fba5562adf9b175b032 453 Gene3D G3DSA:3.40.50.12780 4 311 1.8E-23 T 12-10-2018 AFE_0802 2dd1bd338dae0fba5562adf9b175b032 453 SUPERFAMILY SSF56801 19 435 2.75E-46 T 12-10-2018 AFE_0802 2dd1bd338dae0fba5562adf9b175b032 453 Gene3D G3DSA:3.30.300.30 342 451 3.7E-12 T 12-10-2018 AFE_0802 2dd1bd338dae0fba5562adf9b175b032 453 Pfam PF13193 AMP-binding enzyme C-terminal domain 360 429 3.5E-6 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFE_0153 dfad2273e83e16a3201817b0a5ff587d 230 Pfam PF01988 VIT family 15 222 1.5E-53 T 12-10-2018 IPR008217 Ccc1 family AFE_0710 120653441c48ba043968b0bcdf9805d8 296 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 101 162 7.0E-17 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AFE_0710 120653441c48ba043968b0bcdf9805d8 296 Gene3D G3DSA:3.30.300.130 90 168 2.2E-23 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFE_0710 120653441c48ba043968b0bcdf9805d8 296 SUPERFAMILY SSF117916 92 164 3.71E-19 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFE_0710 120653441c48ba043968b0bcdf9805d8 296 Pfam PF00355 Rieske [2Fe-2S] domain 194 275 1.2E-17 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFE_0710 120653441c48ba043968b0bcdf9805d8 296 Pfam PF01106 NifU-like domain 97 162 1.7E-20 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AFE_0710 120653441c48ba043968b0bcdf9805d8 296 SUPERFAMILY SSF50022 191 295 4.84E-28 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFE_0710 120653441c48ba043968b0bcdf9805d8 296 Gene3D G3DSA:2.102.10.10 190 296 1.1E-22 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFE_0563 7e3e5746a34a9d64163705522c02176c 212 SUPERFAMILY SSF52540 7 192 1.73E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0563 7e3e5746a34a9d64163705522c02176c 212 Gene3D G3DSA:3.30.63.10 41 90 1.1E-22 T 12-10-2018 AFE_0563 7e3e5746a34a9d64163705522c02176c 212 SMART SM00072 7 190 2.8E-63 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit AFE_0563 7e3e5746a34a9d64163705522c02176c 212 ProSitePatterns PS00856 Guanylate kinase-like signature. 42 59 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 AFE_0563 7e3e5746a34a9d64163705522c02176c 212 Gene3D G3DSA:3.40.50.300 2 40 2.7E-5 T 12-10-2018 AFE_0563 7e3e5746a34a9d64163705522c02176c 212 Pfam PF00625 Guanylate kinase 11 188 3.2E-50 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit AFE_0563 7e3e5746a34a9d64163705522c02176c 212 Hamap MF_00328 Guanylate kinase [gmk]. 6 190 36.002 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 AFE_0563 7e3e5746a34a9d64163705522c02176c 212 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 9 187 5.8E-71 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 AFE_0563 7e3e5746a34a9d64163705522c02176c 212 Gene3D G3DSA:3.40.50.300 91 210 2.1E-34 T 12-10-2018 AFE_1678 7b86273b4a429c607be14625a7523ec4 267 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 182 264 1.1E-31 T 12-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal AFE_1678 7b86273b4a429c607be14625a7523ec4 267 SUPERFAMILY SSF52540 29 225 4.17E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1678 7b86273b4a429c607be14625a7523ec4 267 Pfam PF07728 AAA domain (dynein-related subfamily) 36 169 1.4E-29 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFE_1678 7b86273b4a429c607be14625a7523ec4 267 Gene3D G3DSA:3.40.50.300 20 187 1.1E-28 T 12-10-2018 AFE_0400 8419eb915e1285bad0f93f7e95a62616 248 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 189 6.8E-58 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_0400 8419eb915e1285bad0f93f7e95a62616 248 SUPERFAMILY SSF53098 3 175 1.74E-52 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_0400 8419eb915e1285bad0f93f7e95a62616 248 Pfam PF00929 Exonuclease 6 164 4.6E-33 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFE_0400 8419eb915e1285bad0f93f7e95a62616 248 Gene3D G3DSA:3.30.420.10 2 176 2.7E-51 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_0400 8419eb915e1285bad0f93f7e95a62616 248 SMART SM00479 4 173 1.4E-40 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFE_0400 8419eb915e1285bad0f93f7e95a62616 248 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 4 239 9.8E-79 T 12-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_1873 6471be01f30766711c303792102968c6 875 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 450 549 7.3E-29 T 12-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold AFE_1873 6471be01f30766711c303792102968c6 875 Gene3D G3DSA:1.10.390.10 286 449 2.5E-63 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily AFE_1873 6471be01f30766711c303792102968c6 875 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 15 872 0.0 T 12-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 AFE_1873 6471be01f30766711c303792102968c6 875 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 300 315 2.3E-9 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFE_1873 6471be01f30766711c303792102968c6 875 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 132 147 2.3E-9 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFE_1873 6471be01f30766711c303792102968c6 875 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 319 331 2.3E-9 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFE_1873 6471be01f30766711c303792102968c6 875 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 264 274 2.3E-9 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFE_1873 6471be01f30766711c303792102968c6 875 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 182 197 2.3E-9 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFE_1873 6471be01f30766711c303792102968c6 875 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 555 872 3.5E-115 T 12-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal AFE_1873 6471be01f30766711c303792102968c6 875 SUPERFAMILY SSF63737 10 199 2.22E-38 T 12-10-2018 AFE_1873 6471be01f30766711c303792102968c6 875 Pfam PF01433 Peptidase family M1 domain 214 444 5.0E-55 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 AFE_1873 6471be01f30766711c303792102968c6 875 Gene3D G3DSA:2.60.40.1730 18 200 2.2E-64 T 12-10-2018 AFE_1873 6471be01f30766711c303792102968c6 875 Gene3D G3DSA:1.10.1740.60 201 285 3.0E-37 T 12-10-2018 AFE_1873 6471be01f30766711c303792102968c6 875 Gene3D G3DSA:1.25.50.10 553 873 2.0E-113 T 12-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily AFE_1873 6471be01f30766711c303792102968c6 875 SUPERFAMILY SSF55486 211 455 3.48E-72 T 12-10-2018 AFE_1873 6471be01f30766711c303792102968c6 875 Gene3D G3DSA:2.60.40.1840 450 550 3.0E-30 T 12-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily AFE_0016 f2f4ad14e4bc14e314822bc4e6f4b980 146 Pfam PF04361 Protein of unknown function (DUF494) 4 146 6.7E-36 T 12-10-2018 IPR007456 Smg AFE_0016 f2f4ad14e4bc14e314822bc4e6f4b980 146 Hamap MF_00598 Protein Smg [smg]. 4 146 16.085 T 12-10-2018 IPR007456 Smg AFE_0239 cb47cb50e6fdfce2e1e1ff29e61a4d61 385 Pfam PF00155 Aminotransferase class I and II 43 378 7.8E-31 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFE_0239 cb47cb50e6fdfce2e1e1ff29e61a4d61 385 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 10 384 1.1E-157 T 12-10-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 AFE_0239 cb47cb50e6fdfce2e1e1ff29e61a4d61 385 Gene3D G3DSA:3.90.1150.10 23 378 3.4E-123 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0239 cb47cb50e6fdfce2e1e1ff29e61a4d61 385 SUPERFAMILY SSF53383 9 384 1.34E-87 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_0239 cb47cb50e6fdfce2e1e1ff29e61a4d61 385 Gene3D G3DSA:3.40.640.10 65 282 3.4E-123 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_3075 b3aab4d71c39ab5d5ba312bb3b6ccf90 142 Pfam PF00572 Ribosomal protein L13 15 138 2.4E-58 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFE_3075 b3aab4d71c39ab5d5ba312bb3b6ccf90 142 PIRSF PIRSF002181 1 142 1.0E-52 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFE_3075 b3aab4d71c39ab5d5ba312bb3b6ccf90 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 12-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 AFE_3075 b3aab4d71c39ab5d5ba312bb3b6ccf90 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.842 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFE_3075 b3aab4d71c39ab5d5ba312bb3b6ccf90 142 Gene3D G3DSA:3.90.1180.10 1 142 5.9E-63 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 AFE_3075 b3aab4d71c39ab5d5ba312bb3b6ccf90 142 SUPERFAMILY SSF52161 1 139 3.92E-60 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 AFE_3075 b3aab4d71c39ab5d5ba312bb3b6ccf90 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 141 3.8E-64 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_3200 f05df7344117847a5ba0e7e9c00e36d2 611 SUPERFAMILY SSF56235 2 233 1.03E-69 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_3200 f05df7344117847a5ba0e7e9c00e36d2 611 Gene3D G3DSA:3.40.50.10490 449 596 6.7E-136 T 12-10-2018 AFE_3200 f05df7344117847a5ba0e7e9c00e36d2 611 SUPERFAMILY SSF53697 246 611 1.42E-106 T 12-10-2018 AFE_3200 f05df7344117847a5ba0e7e9c00e36d2 611 Gene3D G3DSA:3.60.20.10 2 241 5.8E-76 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_3200 f05df7344117847a5ba0e7e9c00e36d2 611 Gene3D G3DSA:3.40.50.10490 250 610 6.7E-136 T 12-10-2018 AFE_3200 f05df7344117847a5ba0e7e9c00e36d2 611 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 611 39.452 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 AFE_3200 f05df7344117847a5ba0e7e9c00e36d2 611 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 611 1.7E-239 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 AFE_3200 f05df7344117847a5ba0e7e9c00e36d2 611 Pfam PF13522 Glutamine amidotransferase domain 65 194 3.2E-24 T 12-10-2018 AFE_3200 f05df7344117847a5ba0e7e9c00e36d2 611 Pfam PF01380 SIS domain 291 419 6.6E-24 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFE_3200 f05df7344117847a5ba0e7e9c00e36d2 611 Pfam PF01380 SIS domain 465 593 8.7E-28 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFE_1429 926a160c70fa64a157b90e6b333a108d 213 PIRSF PIRSF000005 6 213 1.2E-54 T 12-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 AFE_1429 926a160c70fa64a157b90e6b333a108d 213 SUPERFAMILY SSF46626 44 116 7.09E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_1429 926a160c70fa64a157b90e6b333a108d 213 SUPERFAMILY SSF46626 128 211 6.69E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_1429 926a160c70fa64a157b90e6b333a108d 213 Gene3D G3DSA:1.10.760.10 33 116 4.3E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_1429 926a160c70fa64a157b90e6b333a108d 213 Gene3D G3DSA:1.10.760.10 129 212 2.8E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_1429 926a160c70fa64a157b90e6b333a108d 213 Pfam PF00034 Cytochrome c 130 211 8.1E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_1429 926a160c70fa64a157b90e6b333a108d 213 Pfam PF00034 Cytochrome c 44 112 1.1E-4 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0458 e55d996aac92fe6381ae9400949c0134 172 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 8 166 15.738 T 12-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 AFE_0458 e55d996aac92fe6381ae9400949c0134 172 Pfam PF04390 Lipopolysaccharide-assembly 47 160 3.4E-9 T 12-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 AFE_0458 e55d996aac92fe6381ae9400949c0134 172 Gene3D G3DSA:3.30.160.150 21 168 6.2E-20 T 12-10-2018 AFE_2023 22f271cf44c37b50d2e5e1541d4ea939 394 SUPERFAMILY SSF56059 113 313 1.11E-56 T 12-10-2018 AFE_2023 22f271cf44c37b50d2e5e1541d4ea939 394 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 13 390 5.7E-171 T 12-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 AFE_2023 22f271cf44c37b50d2e5e1541d4ea939 394 SUPERFAMILY SSF51246 319 390 2.04E-16 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFE_2023 22f271cf44c37b50d2e5e1541d4ea939 394 Gene3D G3DSA:3.30.470.20 197 389 1.8E-58 T 12-10-2018 AFE_2023 22f271cf44c37b50d2e5e1541d4ea939 394 SUPERFAMILY SSF52440 3 112 2.01E-32 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFE_2023 22f271cf44c37b50d2e5e1541d4ea939 394 Gene3D G3DSA:3.40.50.20 1 123 6.4E-51 T 12-10-2018 AFE_2023 22f271cf44c37b50d2e5e1541d4ea939 394 Pfam PF02222 ATP-grasp domain 123 295 2.4E-54 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type AFE_2023 22f271cf44c37b50d2e5e1541d4ea939 394 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 7 391 51.111 T 12-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 AFE_2023 22f271cf44c37b50d2e5e1541d4ea939 394 Gene3D G3DSA:3.30.1490.20 124 196 2.7E-32 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFE_2520 ae47452eac15505f4a9624e2cde0fd89 365 Gene3D G3DSA:3.90.1720.10 182 353 4.4E-42 T 12-10-2018 AFE_2520 ae47452eac15505f4a9624e2cde0fd89 365 SUPERFAMILY SSF54001 241 359 1.47E-43 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFE_2520 ae47452eac15505f4a9624e2cde0fd89 365 Pfam PF00877 NlpC/P60 family 252 358 2.3E-28 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFE_0943 ac648213e9ec5f54572a2311a123177e 483 SUPERFAMILY SSF55957 423 480 1.02E-12 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 257 6.7E-11 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 Gene3D G3DSA:3.40.120.10 258 377 4.9E-40 T 12-10-2018 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 262 380 2.7E-13 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 SUPERFAMILY SSF53738 160 259 1.29E-14 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 SUPERFAMILY SSF53738 245 378 5.49E-9 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 SUPERFAMILY SSF53738 2 133 3.92E-26 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 Gene3D G3DSA:3.40.120.10 177 257 2.8E-28 T 12-10-2018 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 Gene3D G3DSA:3.40.120.10 1 142 4.7E-37 T 12-10-2018 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 Gene3D G3DSA:3.30.310.50 379 483 1.3E-25 T 12-10-2018 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 126 2.9E-21 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_0943 ac648213e9ec5f54572a2311a123177e 483 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 417 471 3.6E-7 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 SUPERFAMILY SSF52096 5 312 3.19E-94 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 313 1.0E-141 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 313 47.929 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 131 147 3.8E-48 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 166 179 3.8E-48 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 194 203 3.8E-48 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 85 96 3.8E-48 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 150 163 3.8E-48 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 110 128 3.8E-48 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 Gene3D G3DSA:3.90.226.10 4 313 8.2E-108 T 12-10-2018 AFE_1462 66ee797feb50a5055a38bcbada2ec40c 316 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 145 5.2E-57 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFE_1638 5785e4fb9a98623018d33b2117d57f7e 840 SMART SM00382 466 759 5.8E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1638 5785e4fb9a98623018d33b2117d57f7e 840 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 191 406 5.0E-17 T 12-10-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 AFE_1638 5785e4fb9a98623018d33b2117d57f7e 840 SUPERFAMILY SSF52540 433 753 2.31E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0871 f9d0fa337b7a9544c7b31b96b3339e01 134 Gene3D G3DSA:2.60.40.790 3 134 3.5E-20 T 12-10-2018 IPR008978 HSP20-like chaperone AFE_0871 f9d0fa337b7a9544c7b31b96b3339e01 134 Pfam PF00011 Hsp20/alpha crystallin family 45 130 4.6E-11 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain AFE_0871 f9d0fa337b7a9544c7b31b96b3339e01 134 SUPERFAMILY SSF49764 10 130 1.57E-21 T 12-10-2018 IPR008978 HSP20-like chaperone AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR01098 Topoisomerase IV subunit B signature 351 374 5.2E-32 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR01098 Topoisomerase IV subunit B signature 157 172 5.2E-32 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR01098 Topoisomerase IV subunit B signature 24 37 5.2E-32 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR01098 Topoisomerase IV subunit B signature 375 400 5.2E-32 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR01098 Topoisomerase IV subunit B signature 182 199 5.2E-32 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR01098 Topoisomerase IV subunit B signature 324 339 5.2E-32 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR01098 Topoisomerase IV subunit B signature 307 323 5.2E-32 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR01098 Topoisomerase IV subunit B signature 461 482 5.2E-32 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 SMART SM00387 25 181 1.6E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 31 140 9.8E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR00418 DNA topoisomerase II family signature 29 44 1.1E-58 T 12-10-2018 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR00418 DNA topoisomerase II family signature 516 533 1.1E-58 T 12-10-2018 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR00418 DNA topoisomerase II family signature 586 602 1.1E-58 T 12-10-2018 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR00418 DNA topoisomerase II family signature 498 514 1.1E-58 T 12-10-2018 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR00418 DNA topoisomerase II family signature 427 441 1.1E-58 T 12-10-2018 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR00418 DNA topoisomerase II family signature 111 125 1.1E-58 T 12-10-2018 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR00418 DNA topoisomerase II family signature 536 548 1.1E-58 T 12-10-2018 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR00418 DNA topoisomerase II family signature 64 77 1.1E-58 T 12-10-2018 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 PRINTS PR00418 DNA topoisomerase II family signature 279 292 1.1E-58 T 12-10-2018 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 Gene3D G3DSA:3.40.50.670 403 649 1.5E-80 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 Gene3D G3DSA:3.30.565.10 1 217 1.1E-61 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 SUPERFAMILY SSF54211 225 400 1.1E-37 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 Pfam PF01751 Toprim domain 426 538 7.2E-12 T 12-10-2018 IPR006171 TOPRIM domain AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 Pfam PF00204 DNA gyrase B 225 398 3.6E-39 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 SMART SM00433 32 650 2.3E-164 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 SUPERFAMILY SSF56719 401 647 5.75E-70 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 SUPERFAMILY SSF55874 3 212 8.12E-52 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 Gene3D G3DSA:3.30.230.10 223 402 4.1E-45 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 ProSitePatterns PS00177 DNA topoisomerase II signature. 429 437 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_2029 648cfe9c4d59041cd9ff2886535fe279 656 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 582 646 1.9E-21 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFE_1456 ffaa21b8565ba63452632aa412f61a09 260 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 2 259 44.936 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 AFE_1456 ffaa21b8565ba63452632aa412f61a09 260 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 177 257 2.1E-29 T 12-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 AFE_1456 ffaa21b8565ba63452632aa412f61a09 260 SUPERFAMILY SSF51161 3 259 1.13E-77 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFE_1456 ffaa21b8565ba63452632aa412f61a09 260 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 139 1.6E-5 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_1456 ffaa21b8565ba63452632aa412f61a09 260 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 49 3.4E-13 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_1456 ffaa21b8565ba63452632aa412f61a09 260 Gene3D G3DSA:2.160.10.10 1 191 5.7E-52 T 12-10-2018 AFE_1456 ffaa21b8565ba63452632aa412f61a09 260 PIRSF PIRSF000456 1 260 8.5E-105 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 AFE_1456 ffaa21b8565ba63452632aa412f61a09 260 Gene3D G3DSA:1.20.1180.10 194 259 2.1E-23 T 12-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 AFE_1456 ffaa21b8565ba63452632aa412f61a09 260 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 5 257 2.1E-103 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 AFE_1071 f82650a2fdc476aded01439b27d7e037 179 ProDom PD080812 PLASMID Y4OB BMEII097 AGR_L_107P MLL2216 BMEII0977 ATU4831 68 174 6.0E-39 T 12-10-2018 IPR020358 Uncharacterised protein family Y4oB AFE_1071 f82650a2fdc476aded01439b27d7e037 179 Pfam PF09722 Protein of unknown function (DUF2384) 127 175 1.4E-11 T 12-10-2018 IPR024467 Domain of unknown function DUF2384 AFE_1698 3c337e0c25b726958343a8f88e719f7e 223 SUPERFAMILY SSF53955 15 144 5.63E-14 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFE_1698 3c337e0c25b726958343a8f88e719f7e 223 Gene3D G3DSA:1.10.530.10 7 145 1.5E-9 T 12-10-2018 AFE_1698 3c337e0c25b726958343a8f88e719f7e 223 Pfam PF01464 Transglycosylase SLT domain 7 133 3.5E-14 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 AFE_2679 35db86bccddde5225a0ecfe83b7acbae 462 Gene3D G3DSA:3.40.50.10890 222 406 1.1E-140 T 12-10-2018 AFE_2679 35db86bccddde5225a0ecfe83b7acbae 462 SMART SM00849 13 227 1.6E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_2679 35db86bccddde5225a0ecfe83b7acbae 462 Pfam PF10996 Beta-Casp domain 254 380 5.1E-26 T 12-10-2018 IPR022712 Beta-Casp domain AFE_2679 35db86bccddde5225a0ecfe83b7acbae 462 Pfam PF00753 Metallo-beta-lactamase superfamily 10 200 4.9E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_2679 35db86bccddde5225a0ecfe83b7acbae 462 SMART SM01027 254 380 6.2E-57 T 12-10-2018 IPR022712 Beta-Casp domain AFE_2679 35db86bccddde5225a0ecfe83b7acbae 462 SUPERFAMILY SSF56281 1 461 7.08E-128 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_2679 35db86bccddde5225a0ecfe83b7acbae 462 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 394 453 7.9E-12 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AFE_2679 35db86bccddde5225a0ecfe83b7acbae 462 Gene3D G3DSA:3.60.15.10 6 435 1.1E-140 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_2283 8758a7608a2404d200c53122ba394d96 232 TIGRFAM TIGR02324 CP_lyasePhnL: phosphonate C-P lyase system protein PhnL 3 222 4.2E-91 T 12-10-2018 IPR012701 Phosphonate C-P lyase system, PhnL KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFE_2283 8758a7608a2404d200c53122ba394d96 232 Pfam PF00005 ABC transporter 26 180 1.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2283 8758a7608a2404d200c53122ba394d96 232 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2283 8758a7608a2404d200c53122ba394d96 232 SUPERFAMILY SSF52540 3 224 2.6E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2283 8758a7608a2404d200c53122ba394d96 232 Gene3D G3DSA:3.40.50.300 1 226 1.6E-58 T 12-10-2018 AFE_2283 8758a7608a2404d200c53122ba394d96 232 SMART SM00382 35 228 2.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0360 e11b420114c97462d09f60be31458982 248 Pfam PF01569 PAP2 superfamily 97 209 1.8E-15 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFE_0360 e11b420114c97462d09f60be31458982 248 Gene3D G3DSA:1.20.144.10 122 224 8.8E-19 T 12-10-2018 AFE_0360 e11b420114c97462d09f60be31458982 248 SMART SM00014 92 204 1.3E-13 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFE_0360 e11b420114c97462d09f60be31458982 248 SUPERFAMILY SSF48317 23 213 2.35E-23 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFE_1024 cde56b8b5e6dc2de48b87277f5ecdb55 196 Pfam PF02163 Peptidase family M50 119 182 1.9E-8 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFE_0473 63579a208cdda92022beffe0747f8581 436 Gene3D G3DSA:3.30.360.10 135 347 8.8E-166 T 12-10-2018 AFE_0473 63579a208cdda92022beffe0747f8581 436 Gene3D G3DSA:3.40.50.720 4 339 8.8E-166 T 12-10-2018 AFE_0473 63579a208cdda92022beffe0747f8581 436 Pfam PF00742 Homoserine dehydrogenase 136 314 5.5E-63 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFE_0473 63579a208cdda92022beffe0747f8581 436 SUPERFAMILY SSF51735 3 139 1.14E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0473 63579a208cdda92022beffe0747f8581 436 Pfam PF01842 ACT domain 353 419 5.6E-13 T 12-10-2018 IPR002912 ACT domain AFE_0473 63579a208cdda92022beffe0747f8581 436 PIRSF PIRSF000098 1 433 4.3E-159 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFE_0473 63579a208cdda92022beffe0747f8581 436 SUPERFAMILY SSF55021 351 422 5.39E-12 T 12-10-2018 AFE_0473 63579a208cdda92022beffe0747f8581 436 SUPERFAMILY SSF55347 136 301 1.37E-51 T 12-10-2018 AFE_0473 63579a208cdda92022beffe0747f8581 436 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 128 9.2E-19 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 AFE_0473 63579a208cdda92022beffe0747f8581 436 Gene3D G3DSA:3.30.70.260 348 421 8.8E-166 T 12-10-2018 AFE_0473 63579a208cdda92022beffe0747f8581 436 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 182 204 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFE_0960 4161994eabd724554bc78c0af66adf04 514 SUPERFAMILY SSF81296 412 509 2.1E-12 T 12-10-2018 IPR014756 Immunoglobulin E-set AFE_0960 4161994eabd724554bc78c0af66adf04 514 Gene3D G3DSA:2.60.40.10 417 513 1.3E-17 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFE_0960 4161994eabd724554bc78c0af66adf04 514 SUPERFAMILY SSF74650 36 402 3.45E-127 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFE_0960 4161994eabd724554bc78c0af66adf04 514 PIRSF PIRSF006281 5 511 4.0E-151 T 12-10-2018 IPR014438 Glucan biosynthesis protein MdoG/MdoD AFE_0960 4161994eabd724554bc78c0af66adf04 514 Gene3D G3DSA:2.70.98.10 35 406 5.2E-136 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFE_0960 4161994eabd724554bc78c0af66adf04 514 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 36 506 1.7E-157 T 12-10-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 340 166.936 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 10 235 2.5E-113 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 SUPERFAMILY SSF46785 257 330 1.9E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 250 327 2.0E-25 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 SUPERFAMILY SSF52540 20 252 8.35E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 253 326 5.0E-29 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 Gene3D G3DSA:1.10.10.10 257 334 4.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 Gene3D G3DSA:3.40.50.300 18 181 4.2E-36 T 12-10-2018 AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 326 4.8E-138 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 Gene3D G3DSA:1.10.8.60 182 255 3.0E-30 T 12-10-2018 AFE_0062 d65570faa2b62f09e9edbf5c453ccad2 340 SMART SM00382 51 182 5.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0984 91a3d6a5da1be96a68282af80dfb71b4 107 SUPERFAMILY SSF54862 3 97 3.06E-24 T 12-10-2018 AFE_0984 91a3d6a5da1be96a68282af80dfb71b4 107 Pfam PF11953 Domain of unknown function (DUF3470) 67 106 1.5E-14 T 12-10-2018 IPR022569 Ferredoxin, C-terminal AFE_0984 91a3d6a5da1be96a68282af80dfb71b4 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_0984 91a3d6a5da1be96a68282af80dfb71b4 107 Pfam PF00037 4Fe-4S binding domain 34 55 4.4E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_0984 91a3d6a5da1be96a68282af80dfb71b4 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 6.5E-16 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFE_0984 91a3d6a5da1be96a68282af80dfb71b4 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 6.5E-16 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFE_0984 91a3d6a5da1be96a68282af80dfb71b4 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 6.5E-16 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFE_0984 91a3d6a5da1be96a68282af80dfb71b4 107 Gene3D G3DSA:3.30.70.20 2 102 5.2E-31 T 12-10-2018 AFE_0633 783e6562988a8f813ffbc65c1d729214 211 Pfam PF00510 Cytochrome c oxidase subunit III 23 209 2.5E-11 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0633 783e6562988a8f813ffbc65c1d729214 211 SUPERFAMILY SSF81452 16 208 2.88E-35 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0633 783e6562988a8f813ffbc65c1d729214 211 Gene3D G3DSA:1.20.120.80 23 210 1.7E-35 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_2569 f335cd2b2d713e38fa7350d7e7ef9b20 212 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 71 86 - T 12-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFE_2569 f335cd2b2d713e38fa7350d7e7ef9b20 212 SUPERFAMILY SSF55681 8 198 2.24E-62 T 12-10-2018 AFE_2569 f335cd2b2d713e38fa7350d7e7ef9b20 212 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 27 185 2.2E-52 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFE_2569 f335cd2b2d713e38fa7350d7e7ef9b20 212 Hamap MF_00013 Octanoyltransferase [lipB]. 5 206 33.895 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFE_2569 f335cd2b2d713e38fa7350d7e7ef9b20 212 Pfam PF03099 Biotin/lipoate A/B protein ligase family 64 159 1.1E-6 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFE_2569 f335cd2b2d713e38fa7350d7e7ef9b20 212 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 75 128 2.0E-12 T 12-10-2018 AFE_2569 f335cd2b2d713e38fa7350d7e7ef9b20 212 Gene3D G3DSA:3.30.930.10 3 204 1.5E-56 T 12-10-2018 AFE_2569 f335cd2b2d713e38fa7350d7e7ef9b20 212 PIRSF PIRSF016262 1 209 2.3E-52 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFE_0183 d25efa82ce1e7461afe80e48fae8279c 569 SMART SM00382 320 441 0.0041 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0183 d25efa82ce1e7461afe80e48fae8279c 569 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 387 401 - T 12-10-2018 IPR001482 Type II/IV secretion system protein AFE_0183 d25efa82ce1e7461afe80e48fae8279c 569 Gene3D G3DSA:3.30.300.160 67 145 4.5E-7 T 12-10-2018 AFE_0183 d25efa82ce1e7461afe80e48fae8279c 569 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 47 144 3.1E-17 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal AFE_0183 d25efa82ce1e7461afe80e48fae8279c 569 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 14 568 2.6E-228 T 12-10-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 AFE_0183 d25efa82ce1e7461afe80e48fae8279c 569 SUPERFAMILY SSF160246 9 143 6.02E-28 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily AFE_0183 d25efa82ce1e7461afe80e48fae8279c 569 Gene3D G3DSA:3.30.450.90 157 292 3.8E-44 T 12-10-2018 AFE_0183 d25efa82ce1e7461afe80e48fae8279c 569 SUPERFAMILY SSF52540 178 567 1.29E-101 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0183 d25efa82ce1e7461afe80e48fae8279c 569 Gene3D G3DSA:3.40.50.300 296 568 3.5E-109 T 12-10-2018 AFE_0183 d25efa82ce1e7461afe80e48fae8279c 569 Pfam PF00437 Type II/IV secretion system protein 193 459 3.1E-84 T 12-10-2018 IPR001482 Type II/IV secretion system protein AFE_0461 68a0d665de48163b6b62f06133b2f6b3 213 SMART SM00867 41 210 2.5E-59 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFE_0461 68a0d665de48163b6b62f06133b2f6b3 213 SUPERFAMILY SSF101874 39 212 1.24E-51 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily AFE_0461 68a0d665de48163b6b62f06133b2f6b3 213 Gene3D G3DSA:2.40.128.110 40 213 4.7E-49 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily AFE_0461 68a0d665de48163b6b62f06133b2f6b3 213 Pfam PF04264 YceI-like domain 42 208 1.1E-41 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 177 298 9.5E-19 T 12-10-2018 IPR000014 PAS domain AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SUPERFAMILY SSF55073 602 756 1.73E-45 T 12-10-2018 IPR029787 Nucleotide cyclase AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Pfam PF13185 GAF domain 438 577 5.3E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Pfam PF13185 GAF domain 27 171 2.0E-15 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SUPERFAMILY SSF141868 777 993 3.79E-50 T 12-10-2018 IPR035919 EAL domain superfamily AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Gene3D G3DSA:3.30.70.270 592 761 4.4E-53 T 12-10-2018 AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Pfam PF13426 PAS domain 191 293 1.2E-20 T 12-10-2018 IPR000014 PAS domain AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 596 755 1.2E-42 T 12-10-2018 IPR000160 GGDEF domain AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Gene3D G3DSA:3.30.450.40 411 591 2.9E-13 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Gene3D G3DSA:3.30.450.40 12 178 8.2E-22 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Gene3D G3DSA:3.20.20.450 776 997 6.7E-56 T 12-10-2018 IPR035919 EAL domain superfamily AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SMART SM00065 28 180 7.4E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SMART SM00065 439 587 0.052 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SUPERFAMILY SSF55785 187 293 7.5E-27 T 12-10-2018 IPR035965 PAS domain superfamily AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SMART SM00267 586 760 5.0E-61 T 12-10-2018 IPR000160 GGDEF domain AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SMART SM00091 180 246 2.5E-5 T 12-10-2018 IPR000014 PAS domain AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SMART SM00091 299 365 0.0013 T 12-10-2018 IPR000014 PAS domain AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Pfam PF08448 PAS fold 307 411 9.8E-7 T 12-10-2018 IPR013656 PAS fold-4 AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SMART SM00086 252 294 1.4E-9 T 12-10-2018 IPR001610 PAC motif AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SUPERFAMILY SSF55785 302 409 1.13E-10 T 12-10-2018 IPR035965 PAS domain superfamily AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Gene3D G3DSA:3.30.450.20 179 301 1.3E-38 T 12-10-2018 AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SUPERFAMILY SSF55781 439 588 1.7E-14 T 12-10-2018 AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SMART SM00052 770 1000 7.9E-37 T 12-10-2018 IPR001633 EAL domain AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Gene3D G3DSA:3.30.450.20 302 410 3.9E-14 T 12-10-2018 AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 SUPERFAMILY SSF55781 30 180 1.02E-18 T 12-10-2018 AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Pfam PF00563 EAL domain 776 990 1.0E-45 T 12-10-2018 IPR001633 EAL domain AFE_1707 eed3e475966ef70a2c0c3f4c9353a18d 1057 Pfam PF00990 Diguanylate cyclase, GGDEF domain 597 754 3.0E-45 T 12-10-2018 IPR000160 GGDEF domain AFE_3064 07b59e19c2a521fdec49ab422f97d506 436 Gene3D G3DSA:3.40.50.11280 71 207 8.3E-43 T 12-10-2018 AFE_3064 07b59e19c2a521fdec49ab422f97d506 436 TIGRFAM TIGR02049 gshA_ferroox: glutamate--cysteine ligase 23 427 2.0E-210 T 12-10-2018 IPR011718 Glutamate--cysteine ligase GshA AFE_3064 07b59e19c2a521fdec49ab422f97d506 436 Pfam PF08886 Glutamate-cysteine ligase 23 423 3.7E-182 T 12-10-2018 IPR011718 Glutamate--cysteine ligase GshA AFE_1483 57a1b553fd241784be281d13899d3db1 754 SUPERFAMILY SSF56935 30 754 9.16E-69 T 12-10-2018 AFE_1483 57a1b553fd241784be281d13899d3db1 754 Pfam PF00593 TonB dependent receptor 339 751 3.7E-29 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_1483 57a1b553fd241784be281d13899d3db1 754 Gene3D G3DSA:2.40.170.20 174 754 1.3E-56 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily AFE_1537 0d37f68895b06573f69e464a0fda7358 393 PIRSF PIRSF005572 4 377 2.3E-126 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFE_1537 0d37f68895b06573f69e464a0fda7358 393 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 195 214 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AFE_1537 0d37f68895b06573f69e464a0fda7358 393 Gene3D G3DSA:1.10.260.50 18 279 1.2E-133 T 12-10-2018 AFE_1537 0d37f68895b06573f69e464a0fda7358 393 Gene3D G3DSA:3.90.1150.10 7 370 1.2E-133 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_1537 0d37f68895b06573f69e464a0fda7358 393 Gene3D G3DSA:3.40.640.10 64 236 1.2E-133 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_1537 0d37f68895b06573f69e464a0fda7358 393 Pfam PF00266 Aminotransferase class-V 7 366 1.5E-79 T 12-10-2018 IPR000192 Aminotransferase class V domain AFE_1537 0d37f68895b06573f69e464a0fda7358 393 SUPERFAMILY SSF53383 7 373 2.82E-99 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_2122 290cb5df13fc4fc62163a9b0109ac12e 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 230 3.6E-34 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFE_2122 290cb5df13fc4fc62163a9b0109ac12e 329 TIGRFAM TIGR03466 HpnA: hopanoid-associated sugar epimerase 1 329 7.8E-153 T 12-10-2018 IPR017829 Hopanoid-associated sugar epimerase KEGG: 00941+1.1.1.219|MetaCyc: PWY-5152 AFE_2122 290cb5df13fc4fc62163a9b0109ac12e 329 Gene3D G3DSA:3.40.50.720 1 329 9.4E-111 T 12-10-2018 AFE_2122 290cb5df13fc4fc62163a9b0109ac12e 329 SUPERFAMILY SSF51735 1 327 5.14E-65 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3136 3d80259f2895640222d1f41028083e5d 417 SMART SM00388 198 263 0.0079 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_3136 3d80259f2895640222d1f41028083e5d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 355 1.9E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_3136 3d80259f2895640222d1f41028083e5d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 388 1.9E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_3136 3d80259f2895640222d1f41028083e5d 417 SMART SM00387 306 410 4.7E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_3136 3d80259f2895640222d1f41028083e5d 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 409 9.8E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_3136 3d80259f2895640222d1f41028083e5d 417 Gene3D G3DSA:3.30.565.10 269 412 1.8E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_3136 3d80259f2895640222d1f41028083e5d 417 Gene3D G3DSA:1.10.287.130 182 260 2.3E-10 T 12-10-2018 AFE_3136 3d80259f2895640222d1f41028083e5d 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 199 255 3.8E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_3136 3d80259f2895640222d1f41028083e5d 417 SUPERFAMILY SSF47384 197 255 7.85E-7 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_3136 3d80259f2895640222d1f41028083e5d 417 SUPERFAMILY SSF55874 271 409 2.62E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2832 90fa2bfec5ed416064dd53e0956fe724 294 SUPERFAMILY SSF53686 5 289 6.68E-93 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFE_2832 90fa2bfec5ed416064dd53e0956fe724 294 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 30 48 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 AFE_2832 90fa2bfec5ed416064dd53e0956fe724 294 TIGRFAM TIGR01138 cysM: cysteine synthase B 4 292 1.8E-131 T 12-10-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AFE_2832 90fa2bfec5ed416064dd53e0956fe724 294 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 281 4.0E-68 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFE_2832 90fa2bfec5ed416064dd53e0956fe724 294 TIGRFAM TIGR01136 cysKM: cysteine synthase 5 292 2.4E-117 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AFE_2832 90fa2bfec5ed416064dd53e0956fe724 294 Gene3D G3DSA:3.40.50.1100 35 140 1.3E-105 T 12-10-2018 AFE_2832 90fa2bfec5ed416064dd53e0956fe724 294 Gene3D G3DSA:3.40.50.1100 8 288 1.3E-105 T 12-10-2018 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Pfam PF00140 Sigma-70 factor, region 1.2 101 132 8.0E-14 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 379 616 8.4E-121 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 407 420 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Gene3D G3DSA:1.10.601.10 116 452 9.4E-122 T 12-10-2018 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Pfam PF03979 Sigma-70 factor, region 1.1 5 84 9.5E-29 T 12-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 SUPERFAMILY SSF88946 118 450 1.44E-96 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 PRINTS PR00046 Major sigma-70 factor signature 577 592 6.9E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 PRINTS PR00046 Major sigma-70 factor signature 431 439 6.9E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 PRINTS PR00046 Major sigma-70 factor signature 407 420 6.9E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 PRINTS PR00046 Major sigma-70 factor signature 556 568 6.9E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 PRINTS PR00046 Major sigma-70 factor signature 592 603 6.9E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Pfam PF04542 Sigma-70 region 2 383 452 1.7E-21 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Pfam PF04539 Sigma-70 region 3 462 538 1.1E-30 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Gene3D G3DSA:1.10.10.10 456 531 3.3E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Pfam PF04546 Sigma-70, non-essential region 142 352 4.8E-53 T 12-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 SUPERFAMILY SSF88659 513 616 3.71E-25 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 SUPERFAMILY SSF88659 456 529 2.05E-21 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Gene3D G3DSA:1.10.10.10 532 618 3.8E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 577 603 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 5 617 43.66 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 379 605 3.0E-38 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Pfam PF04545 Sigma-70, region 4 555 605 1.1E-17 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFE_2336 50e8bcbc12e66c1648f132b0f44e533f 624 Gene3D G3DSA:1.10.220.120 2 65 2.3E-28 T 12-10-2018 AFE_1684 7c3c5999f79bc943e8f6495f40f69893 100 SMART SM00877 9 86 1.3E-28 T 12-10-2018 IPR000249 Microcompartment protein, bacteria AFE_1684 7c3c5999f79bc943e8f6495f40f69893 100 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 10 71 8.0E-20 T 12-10-2018 AFE_1684 7c3c5999f79bc943e8f6495f40f69893 100 Gene3D G3DSA:3.30.70.1710 1 100 8.0E-35 T 12-10-2018 AFE_1684 7c3c5999f79bc943e8f6495f40f69893 100 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 27 46 - T 12-10-2018 IPR020808 Bacterial microcompartments protein, conserved site AFE_1684 7c3c5999f79bc943e8f6495f40f69893 100 SUPERFAMILY SSF143414 10 96 2.62E-27 T 12-10-2018 IPR037233 CcmK-like superfamily AFE_1684 7c3c5999f79bc943e8f6495f40f69893 100 Pfam PF00936 BMC domain 10 85 1.6E-24 T 12-10-2018 IPR000249 Microcompartment protein, bacteria AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 Pfam PF01583 Adenylylsulphate kinase 441 590 4.3E-70 T 12-10-2018 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 Gene3D G3DSA:2.40.30.10 218 305 9.7E-25 T 12-10-2018 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 SUPERFAMILY SSF50465 309 410 4.6E-33 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 SUPERFAMILY SSF50447 219 305 1.29E-20 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 SUPERFAMILY SSF52540 3 212 1.47E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 Gene3D G3DSA:3.40.50.300 417 604 4.6E-73 T 12-10-2018 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 PRINTS PR00315 GTP-binding elongation factor signature 67 75 3.6E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 PRINTS PR00315 GTP-binding elongation factor signature 103 114 3.6E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 PRINTS PR00315 GTP-binding elongation factor signature 6 19 3.6E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 PRINTS PR00315 GTP-binding elongation factor signature 140 149 3.6E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 PRINTS PR00315 GTP-binding elongation factor signature 87 97 3.6E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 Gene3D G3DSA:2.40.30.10 308 410 8.2E-34 T 12-10-2018 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 438 604 36.26 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 Pfam PF00009 Elongation factor Tu GTP binding domain 6 203 6.5E-41 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 424 592 7.1E-70 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 Gene3D G3DSA:3.40.50.300 2 213 3.3E-65 T 12-10-2018 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 1 439 46.375 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 SUPERFAMILY SSF52540 435 600 3.45E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2971 a5a6b9f87cbe3b1f9539ca67dbc445f6 604 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 5 410 2.1E-181 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFE_2760 de171747b5fb45491f29d100b34729af 365 Pfam PF03462 PCRF domain 17 208 4.8E-65 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 AFE_2760 de171747b5fb45491f29d100b34729af 365 SUPERFAMILY SSF75620 15 358 4.19E-130 T 12-10-2018 AFE_2760 de171747b5fb45491f29d100b34729af 365 Gene3D G3DSA:3.30.160.20 215 297 4.5E-94 T 12-10-2018 AFE_2760 de171747b5fb45491f29d100b34729af 365 Gene3D G3DSA:3.30.70.1660 116 347 4.5E-94 T 12-10-2018 AFE_2760 de171747b5fb45491f29d100b34729af 365 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 361 1.6E-150 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 AFE_2760 de171747b5fb45491f29d100b34729af 365 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 233 249 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFE_2760 de171747b5fb45491f29d100b34729af 365 SMART SM00937 69 183 4.6E-56 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 AFE_2760 de171747b5fb45491f29d100b34729af 365 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 7 362 39.075 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 AFE_2760 de171747b5fb45491f29d100b34729af 365 Gene3D G3DSA:1.20.58.410 6 99 3.8E-5 T 12-10-2018 AFE_2760 de171747b5fb45491f29d100b34729af 365 Pfam PF00472 RF-1 domain 219 326 2.7E-41 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFE_3247 354ce1d09d8d312ef7fbc699074687f2 220 Gene3D G3DSA:3.20.20.70 4 219 2.8E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_3247 354ce1d09d8d312ef7fbc699074687f2 220 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 135 157 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFE_3247 354ce1d09d8d312ef7fbc699074687f2 220 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 214 1.2E-94 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFE_3247 354ce1d09d8d312ef7fbc699074687f2 220 SUPERFAMILY SSF51366 1 217 5.25E-78 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFE_3247 354ce1d09d8d312ef7fbc699074687f2 220 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 202 4.9E-89 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFE_3247 354ce1d09d8d312ef7fbc699074687f2 220 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFE_3247 354ce1d09d8d312ef7fbc699074687f2 220 PIRSF PIRSF001461 1 220 7.4E-101 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFE_2482 b6f04b4aeaf760500f6bdb5e0c20888e 681 SUPERFAMILY SSF74650 3 273 2.98E-84 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFE_2482 b6f04b4aeaf760500f6bdb5e0c20888e 681 Pfam PF00723 Glycosyl hydrolases family 15 373 672 3.6E-19 T 12-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 AFE_2482 b6f04b4aeaf760500f6bdb5e0c20888e 681 Gene3D G3DSA:2.70.98.10 2 271 3.8E-94 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFE_2482 b6f04b4aeaf760500f6bdb5e0c20888e 681 Gene3D G3DSA:1.50.10.10 276 681 1.9E-153 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFE_2482 b6f04b4aeaf760500f6bdb5e0c20888e 681 Pfam PF09137 Glucodextranase, domain N 6 270 5.1E-97 T 12-10-2018 IPR015220 Glucodextranase, N-terminal KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 AFE_2482 b6f04b4aeaf760500f6bdb5e0c20888e 681 ProSitePatterns PS00820 Glucoamylase active site region signature. 426 436 - T 12-10-2018 IPR000165 Glucoamylase GO:0004339|GO:0005976 KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 AFE_2482 b6f04b4aeaf760500f6bdb5e0c20888e 681 SUPERFAMILY SSF48208 279 673 1.21E-75 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFE_0300 c3ba39bba92342aea26504451ca4a3ec 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 151 2.2E-59 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0300 c3ba39bba92342aea26504451ca4a3ec 154 SUPERFAMILY SSF52121 5 154 4.19E-63 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0300 c3ba39bba92342aea26504451ca4a3ec 154 Gene3D G3DSA:3.40.50.960 2 154 2.5E-63 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0300 c3ba39bba92342aea26504451ca4a3ec 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 150 9.9E-59 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0300 c3ba39bba92342aea26504451ca4a3ec 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 9 154 32.028 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_2946 e5ecb531c5bc525b3b00ceb1ea931655 198 Pfam PF01625 Peptide methionine sulfoxide reductase 21 173 6.3E-59 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFE_2946 e5ecb531c5bc525b3b00ceb1ea931655 198 SUPERFAMILY SSF55068 16 184 1.44E-67 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFE_2946 e5ecb531c5bc525b3b00ceb1ea931655 198 Gene3D G3DSA:3.30.1060.10 5 183 1.6E-62 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFE_2946 e5ecb531c5bc525b3b00ceb1ea931655 198 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 18 178 34.528 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFE_2946 e5ecb531c5bc525b3b00ceb1ea931655 198 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 21 170 6.5E-52 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFE_0345 6b121fce7839a609ee54af0a9f6e78e0 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 58 6.9E-22 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0345 6b121fce7839a609ee54af0a9f6e78e0 61 Gene3D G3DSA:3.30.1390.20 1 59 3.8E-24 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily AFE_0345 6b121fce7839a609ee54af0a9f6e78e0 61 SUPERFAMILY SSF55129 3 60 4.19E-19 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily AFE_0345 6b121fce7839a609ee54af0a9f6e78e0 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 19.102 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0345 6b121fce7839a609ee54af0a9f6e78e0 61 Pfam PF00327 Ribosomal protein L30p/L7e 5 54 8.6E-17 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AFE_0345 6b121fce7839a609ee54af0a9f6e78e0 61 PIRSF PIRSF002211 1 61 1.4E-24 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 186 2.7E-62 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 Gene3D G3DSA:1.20.5.100 204 234 3.4E-15 T 12-10-2018 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 Gene3D G3DSA:3.40.50.720 1 202 6.8E-78 T 12-10-2018 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 SMART SM00984 320 424 6.4E-55 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 420 3.8E-136 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 296 3.9E-37 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 PIRSF PIRSF000124 1 439 1.1E-147 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 424 1.6E-32 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 SUPERFAMILY SSF51735 1 195 6.43E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 PIRSF PIRSF500134 1 440 7.0E-185 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 SUPERFAMILY SSF48179 204 301 4.83E-33 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 SUPERFAMILY SSF52413 306 434 7.59E-41 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFE_1343 fef8d4ba2fc81bc8721dd73ffe8b838e 440 Gene3D G3DSA:3.40.50.720 235 440 3.0E-83 T 12-10-2018 AFE_0826 f0e7935bcdb6ef81f8c8259e4ab6082c 520 Pfam PF02384 N-6 DNA Methylase 163 483 5.1E-86 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 AFE_0826 f0e7935bcdb6ef81f8c8259e4ab6082c 520 Pfam PF12161 HsdM N-terminal domain 11 151 5.4E-28 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain AFE_0826 f0e7935bcdb6ef81f8c8259e4ab6082c 520 Gene3D G3DSA:3.40.50.150 163 468 9.3E-84 T 12-10-2018 AFE_0826 f0e7935bcdb6ef81f8c8259e4ab6082c 520 Gene3D G3DSA:1.20.1260.30 3 79 3.9E-13 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily AFE_0826 f0e7935bcdb6ef81f8c8259e4ab6082c 520 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 202 4.2E-13 T 12-10-2018 AFE_0826 f0e7935bcdb6ef81f8c8259e4ab6082c 520 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 328 352 4.2E-13 T 12-10-2018 AFE_0826 f0e7935bcdb6ef81f8c8259e4ab6082c 520 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 210 224 4.2E-13 T 12-10-2018 AFE_0826 f0e7935bcdb6ef81f8c8259e4ab6082c 520 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 290 302 4.2E-13 T 12-10-2018 AFE_0826 f0e7935bcdb6ef81f8c8259e4ab6082c 520 SUPERFAMILY SSF53335 10 519 1.44E-115 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2630 8fd5b2bc2a75d229b0732cc949b87006 118 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 118 20.833 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 AFE_2630 8fd5b2bc2a75d229b0732cc949b87006 118 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 117 3.3E-41 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2630 8fd5b2bc2a75d229b0732cc949b87006 118 Gene3D G3DSA:1.20.58.1610 1 118 7.2E-47 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_1407 86cf412151e9a0e34fe7957c58949211 260 SUPERFAMILY SSF52402 16 222 2.09E-48 T 12-10-2018 AFE_1407 86cf412151e9a0e34fe7957c58949211 260 Pfam PF01171 PP-loop family 38 202 6.1E-17 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AFE_1407 86cf412151e9a0e34fe7957c58949211 260 PIRSF PIRSF004976 9 251 1.1E-58 T 12-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 AFE_1407 86cf412151e9a0e34fe7957c58949211 260 Gene3D G3DSA:3.40.50.620 13 251 4.4E-47 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2551 83e847764fa561d5015080fe89c207fc 239 Gene3D G3DSA:1.10.1060.10 28 140 4.4E-9 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_2551 83e847764fa561d5015080fe89c207fc 239 Pfam PF13534 4Fe-4S dicluster domain 62 123 1.0E-9 T 12-10-2018 AFE_2551 83e847764fa561d5015080fe89c207fc 239 SUPERFAMILY SSF46548 31 135 1.43E-17 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_2551 83e847764fa561d5015080fe89c207fc 239 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 109 120 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_1345 b41468fa9552b8fb62a29ec07a61cc6f 231 Gene3D G3DSA:3.40.50.150 15 183 9.6E-30 T 12-10-2018 AFE_1345 b41468fa9552b8fb62a29ec07a61cc6f 231 SUPERFAMILY SSF53335 13 226 2.32E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_1345 b41468fa9552b8fb62a29ec07a61cc6f 231 Pfam PF13489 Methyltransferase domain 24 164 3.0E-13 T 12-10-2018 AFE_1973 cb55ff45ddcdf71a2f87138a51685fd6 264 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 9 263 36.952 T 12-10-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 AFE_1973 cb55ff45ddcdf71a2f87138a51685fd6 264 Gene3D G3DSA:3.10.270.10 6 263 1.6E-97 T 12-10-2018 AFE_1973 cb55ff45ddcdf71a2f87138a51685fd6 264 Pfam PF02649 Type I GTP cyclohydrolase folE2 9 258 2.2E-95 T 12-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 AFE_0697 a2ae77dac192d94daac8735084c69300 369 Gene3D G3DSA:3.40.50.720 174 312 1.9E-145 T 12-10-2018 AFE_0697 a2ae77dac192d94daac8735084c69300 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 150 4.4E-25 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFE_0697 a2ae77dac192d94daac8735084c69300 369 Pfam PF00107 Zinc-binding dehydrogenase 197 321 2.7E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFE_0697 a2ae77dac192d94daac8735084c69300 369 SUPERFAMILY SSF50129 1 184 2.59E-69 T 12-10-2018 IPR011032 GroES-like superfamily AFE_0697 a2ae77dac192d94daac8735084c69300 369 SUPERFAMILY SSF51735 160 334 2.5E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0697 a2ae77dac192d94daac8735084c69300 369 SUPERFAMILY SSF50129 318 369 1.69E-11 T 12-10-2018 IPR011032 GroES-like superfamily AFE_0697 a2ae77dac192d94daac8735084c69300 369 Gene3D G3DSA:3.90.180.10 6 364 1.9E-145 T 12-10-2018 AFE_0697 a2ae77dac192d94daac8735084c69300 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFE_0697 a2ae77dac192d94daac8735084c69300 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 3 369 1.8E-181 T 12-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 AFE_3052 6d6a6fbd980b3ad90bbef2288693d7cd 118 Gene3D G3DSA:3.30.190.10 1 116 3.0E-45 T 12-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_3052 6d6a6fbd980b3ad90bbef2288693d7cd 118 Pfam PF00101 Ribulose bisphosphate carboxylase, small chain 19 114 5.2E-39 T 12-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_3052 6d6a6fbd980b3ad90bbef2288693d7cd 118 SUPERFAMILY SSF55239 12 115 5.63E-42 T 12-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_3052 6d6a6fbd980b3ad90bbef2288693d7cd 118 SMART SM00961 18 115 1.3E-46 T 12-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 Pfam PF00873 AcrB/AcrD/AcrF family 6 1018 6.0E-283 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 Gene3D G3DSA:3.30.2090.10 713 801 2.1E-293 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 Gene3D G3DSA:1.20.1640.10 10 511 2.1E-293 T 12-10-2018 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 SUPERFAMILY SSF82866 800 1020 4.84E-44 T 12-10-2018 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 SUPERFAMILY SSF82714 714 798 2.62E-15 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 Gene3D G3DSA:3.30.70.1430 566 660 2.1E-293 T 12-10-2018 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 Gene3D G3DSA:3.30.70.1430 40 809 2.1E-293 T 12-10-2018 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 Gene3D G3DSA:3.30.70.1440 661 858 2.1E-293 T 12-10-2018 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 SUPERFAMILY SSF82693 136 322 1.62E-19 T 12-10-2018 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 Gene3D G3DSA:3.30.70.1320 135 326 2.1E-293 T 12-10-2018 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.9E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.9E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.9E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.9E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 1.9E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.9E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.9E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.9E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 SUPERFAMILY SSF82714 183 262 3.01E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 SUPERFAMILY SSF82693 40 132 1.29E-21 T 12-10-2018 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 SUPERFAMILY SSF82866 290 490 4.71E-42 T 12-10-2018 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 Gene3D G3DSA:3.30.2090.10 179 269 2.1E-293 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 Gene3D G3DSA:1.20.1640.10 512 1015 2.1E-293 T 12-10-2018 AFE_2104 a8cdeb68de8768c7699e1954ea1812b1 1034 SUPERFAMILY SSF82693 565 660 7.32E-7 T 12-10-2018 AFE_0829 5e5d255d53366c032e21ab880a55db9a 409 SUPERFAMILY SSF116734 224 391 1.19E-25 T 12-10-2018 AFE_0829 5e5d255d53366c032e21ab880a55db9a 409 SUPERFAMILY SSF116734 25 221 7.19E-44 T 12-10-2018 AFE_0829 5e5d255d53366c032e21ab880a55db9a 409 Gene3D G3DSA:3.90.220.20 236 377 1.4E-86 T 12-10-2018 AFE_0829 5e5d255d53366c032e21ab880a55db9a 409 Pfam PF01420 Type I restriction modification DNA specificity domain 24 199 2.7E-24 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFE_0829 5e5d255d53366c032e21ab880a55db9a 409 Pfam PF01420 Type I restriction modification DNA specificity domain 232 396 3.6E-14 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFE_0829 5e5d255d53366c032e21ab880a55db9a 409 Gene3D G3DSA:3.90.220.20 25 171 1.4E-86 T 12-10-2018 AFE_0829 5e5d255d53366c032e21ab880a55db9a 409 Gene3D G3DSA:1.10.287.1120 172 398 1.4E-86 T 12-10-2018 AFE_1823 348b0e5d0ccde4ec3d9b613f05a70803 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 186 2.8E-28 T 12-10-2018 AFE_1823 348b0e5d0ccde4ec3d9b613f05a70803 224 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 7 214 2.2E-49 T 12-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 AFE_1823 348b0e5d0ccde4ec3d9b613f05a70803 224 SUPERFAMILY SSF56784 6 213 1.36E-49 T 12-10-2018 IPR036412 HAD-like superfamily AFE_1823 348b0e5d0ccde4ec3d9b613f05a70803 224 Gene3D G3DSA:1.10.150.240 19 85 1.4E-49 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFE_1823 348b0e5d0ccde4ec3d9b613f05a70803 224 Gene3D G3DSA:3.40.50.1000 7 207 1.4E-49 T 12-10-2018 IPR023214 HAD superfamily AFE_0059 4f313498bc572d5f3e1147089b51ed5a 250 Gene3D G3DSA:1.10.10.200 1 80 3.7E-34 T 12-10-2018 IPR017856 Integrase-like, N-terminal AFE_0059 4f313498bc572d5f3e1147089b51ed5a 250 SUPERFAMILY SSF75625 3 245 3.66E-96 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0059 4f313498bc572d5f3e1147089b51ed5a 250 Gene3D G3DSA:3.30.70.980 130 204 3.1E-56 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0059 4f313498bc572d5f3e1147089b51ed5a 250 Pfam PF01709 Transcriptional regulator 5 235 1.6E-96 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0059 4f313498bc572d5f3e1147089b51ed5a 250 Gene3D G3DSA:3.30.70.980 85 235 3.1E-56 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0059 4f313498bc572d5f3e1147089b51ed5a 250 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 238 36.585 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0059 4f313498bc572d5f3e1147089b51ed5a 250 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 236 8.8E-98 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_2594 aa6a4a28de6ff066d99026d8fd3fe373 204 Gene3D G3DSA:1.20.1050.10 82 188 3.4E-74 T 12-10-2018 AFE_2594 aa6a4a28de6ff066d99026d8fd3fe373 204 Gene3D G3DSA:3.40.30.10 3 192 3.4E-74 T 12-10-2018 AFE_2594 aa6a4a28de6ff066d99026d8fd3fe373 204 SUPERFAMILY SSF47616 81 198 3.62E-30 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily AFE_2594 aa6a4a28de6ff066d99026d8fd3fe373 204 Pfam PF13409 Glutathione S-transferase, N-terminal domain 15 75 1.8E-8 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFE_2594 aa6a4a28de6ff066d99026d8fd3fe373 204 Pfam PF00043 Glutathione S-transferase, C-terminal domain 101 189 3.9E-13 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal AFE_2594 aa6a4a28de6ff066d99026d8fd3fe373 204 SUPERFAMILY SSF52833 1 79 1.31E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0202 71e7d55da274915e818b68fb6c18afed 280 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 48 270 18.765 T 12-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 AFE_0202 71e7d55da274915e818b68fb6c18afed 280 Pfam PF08478 POTRA domain, FtsQ-type 75 142 3.9E-16 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type AFE_0202 71e7d55da274915e818b68fb6c18afed 280 Gene3D G3DSA:3.40.50.11690 145 273 4.0E-28 T 12-10-2018 AFE_0202 71e7d55da274915e818b68fb6c18afed 280 Pfam PF03799 Cell division protein FtsQ 148 262 6.4E-16 T 12-10-2018 IPR005548 Cell division protein FtsQ/DivIB AFE_0202 71e7d55da274915e818b68fb6c18afed 280 Gene3D G3DSA:3.10.20.310 74 144 4.3E-15 T 12-10-2018 AFE_0328 7f4c95c0164856601f6dbcf13b2bbbbd 205 Pfam PF00573 Ribosomal protein L4/L1 family 16 202 4.8E-48 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 AFE_0328 7f4c95c0164856601f6dbcf13b2bbbbd 205 SUPERFAMILY SSF52166 1 204 4.84E-60 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 AFE_0328 7f4c95c0164856601f6dbcf13b2bbbbd 205 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 16 200 3.7E-59 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0328 7f4c95c0164856601f6dbcf13b2bbbbd 205 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 205 27.268 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0328 7f4c95c0164856601f6dbcf13b2bbbbd 205 Gene3D G3DSA:3.40.1370.10 2 205 5.4E-56 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 AFE_0135 0699b3f456edd65b5d87d9d9c6b485dd 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.5E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0135 0699b3f456edd65b5d87d9d9c6b485dd 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.5E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0135 0699b3f456edd65b5d87d9d9c6b485dd 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.5E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0135 0699b3f456edd65b5d87d9d9c6b485dd 310 SUPERFAMILY SSF53850 92 299 5.27E-39 T 12-10-2018 AFE_0135 0699b3f456edd65b5d87d9d9c6b485dd 310 Gene3D G3DSA:3.40.190.10 166 271 9.3E-75 T 12-10-2018 AFE_0135 0699b3f456edd65b5d87d9d9c6b485dd 310 Pfam PF03466 LysR substrate binding domain 90 297 3.5E-39 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_0135 0699b3f456edd65b5d87d9d9c6b485dd 310 Gene3D G3DSA:1.10.10.10 3 92 6.8E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0135 0699b3f456edd65b5d87d9d9c6b485dd 310 Gene3D G3DSA:3.40.190.10 93 294 9.3E-75 T 12-10-2018 AFE_0135 0699b3f456edd65b5d87d9d9c6b485dd 310 SUPERFAMILY SSF46785 3 114 4.89E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0135 0699b3f456edd65b5d87d9d9c6b485dd 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 65 1.3E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 Gene3D G3DSA:1.10.8.60 314 421 1.3E-41 T 12-10-2018 AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 SUPERFAMILY SSF52540 60 398 2.8E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 Pfam PF06689 ClpX C4-type zinc finger 13 49 4.9E-20 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 SUPERFAMILY SSF57716 13 48 1.05E-11 T 12-10-2018 AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 409 6.9E-204 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 3 413 53.144 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 SMART SM01086 315 410 2.2E-35 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 Gene3D G3DSA:3.30.50.30 3 52 7.6E-24 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 SMART SM00994 12 51 3.3E-24 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 315 391 4.0E-16 T 12-10-2018 IPR019489 Clp ATPase, C-terminal AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 SMART SM00382 110 265 3.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 Pfam PF07724 AAA domain (Cdc48 subfamily) 111 308 1.2E-49 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_0911 db9cfe256e69127756e7e7c96fb66431 423 Gene3D G3DSA:3.40.50.300 56 313 1.9E-107 T 12-10-2018 AFE_0555 260b04fbe4ac3df2140e0de94b7854bb 152 ProSitePatterns PS00855 Signal peptidases II signature. 97 109 - T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFE_0555 260b04fbe4ac3df2140e0de94b7854bb 152 TIGRFAM TIGR00077 lspA: signal peptidase II 4 149 2.5E-36 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFE_0555 260b04fbe4ac3df2140e0de94b7854bb 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 46 54 1.5E-19 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFE_0555 260b04fbe4ac3df2140e0de94b7854bb 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 94 109 1.5E-19 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFE_0555 260b04fbe4ac3df2140e0de94b7854bb 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 130 146 1.5E-19 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFE_0555 260b04fbe4ac3df2140e0de94b7854bb 152 Pfam PF01252 Signal peptidase (SPase) II 9 149 4.5E-38 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFE_0555 260b04fbe4ac3df2140e0de94b7854bb 152 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 3 152 16.481 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFE_0842 33aa50a60350d170ca6b21e61dc6953f 111 Gene3D G3DSA:3.30.2010.10 1 103 1.4E-20 T 12-10-2018 AFE_0842 33aa50a60350d170ca6b21e61dc6953f 111 Pfam PF01863 Protein of unknown function DUF45 7 100 1.2E-24 T 12-10-2018 IPR002725 Protein of unknown function DUF45 AFE_1958 652cb24f738cf617716a3d76768677e3 576 Gene3D G3DSA:3.10.20.310 182 257 2.3E-13 T 12-10-2018 AFE_1958 652cb24f738cf617716a3d76768677e3 576 Gene3D G3DSA:3.10.20.310 94 181 4.3E-10 T 12-10-2018 AFE_1958 652cb24f738cf617716a3d76768677e3 576 Pfam PF07244 Surface antigen variable number repeat 183 242 3.9E-8 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFE_1958 652cb24f738cf617716a3d76768677e3 576 Gene3D G3DSA:2.40.160.50 259 576 5.8E-75 T 12-10-2018 AFE_1958 652cb24f738cf617716a3d76768677e3 576 Pfam PF01103 Surface antigen 283 573 1.6E-28 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 AFE_2322 026dfdef5a1c6efb492fd6bef16f6467 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 227 5.6E-16 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFE_2322 026dfdef5a1c6efb492fd6bef16f6467 318 SUPERFAMILY SSF51735 1 304 3.56E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2322 026dfdef5a1c6efb492fd6bef16f6467 318 Gene3D G3DSA:3.40.50.720 1 310 3.8E-43 T 12-10-2018 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 Pfam PF00579 tRNA synthetases class I (W and Y) 36 323 7.8E-80 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 Gene3D G3DSA:3.40.50.620 6 222 1.6E-67 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 1.0E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 51 73 1.0E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 166 181 1.0E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 1.0E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 26 403 1.1E-109 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 SUPERFAMILY SSF52374 14 322 8.31E-89 T 12-10-2018 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 3 403 47.363 T 12-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 SUPERFAMILY SSF55174 326 403 2.09E-16 T 12-10-2018 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 Gene3D G3DSA:1.10.240.10 223 333 9.9E-29 T 12-10-2018 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 SMART SM00363 342 404 8.5E-9 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 Gene3D G3DSA:3.10.290.10 334 403 1.3E-15 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFE_3085 92ed2e9b640c916e71d9cc3676f15fc5 407 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 57 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_1331 a499bba8c5cf7ff98c0f7b0146477632 122 SUPERFAMILY SSF110849 12 60 5.93E-7 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 PIRSF PIRSF002133 1 123 9.6E-55 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 1.3E-70 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 SUPERFAMILY SSF50249 2 123 3.17E-53 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.9E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.9E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.9E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.9E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.9E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.9E-61 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 41.114 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 Gene3D G3DSA:2.40.50.140 1 123 1.4E-64 T 12-10-2018 AFE_0322 d8215b2cc5002d973604fea04c832e2a 123 Pfam PF00164 Ribosomal protein S12/S23 13 123 1.3E-43 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_1351 3ed6a5cd552404a18f322cbb7b8e6bea 390 Pfam PF00534 Glycosyl transferases group 1 199 353 5.8E-27 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1351 3ed6a5cd552404a18f322cbb7b8e6bea 390 SUPERFAMILY SSF53756 6 376 1.37E-73 T 12-10-2018 AFE_1351 3ed6a5cd552404a18f322cbb7b8e6bea 390 Pfam PF13439 Glycosyltransferase Family 4 18 187 5.6E-22 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_1351 3ed6a5cd552404a18f322cbb7b8e6bea 390 Gene3D G3DSA:3.40.50.2000 198 357 6.2E-41 T 12-10-2018 AFE_1351 3ed6a5cd552404a18f322cbb7b8e6bea 390 Gene3D G3DSA:3.40.50.2000 5 197 1.1E-25 T 12-10-2018 AFE_0758 73a6fe7cfefa5048acde4822d52d9a9a 171 Gene3D G3DSA:2.60.15.10 1 133 7.5E-32 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_0758 73a6fe7cfefa5048acde4822d52d9a9a 171 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 12 88 5.0E-19 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_0758 73a6fe7cfefa5048acde4822d52d9a9a 171 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 6 135 6.6E-32 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_0758 73a6fe7cfefa5048acde4822d52d9a9a 171 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 5 134 19.739 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_0758 73a6fe7cfefa5048acde4822d52d9a9a 171 SUPERFAMILY SSF51344 6 85 3.53E-20 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_0758 73a6fe7cfefa5048acde4822d52d9a9a 171 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 7 85 2.9E-24 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_0549 b068a1fc4c699a3d65be8b3ccc559d50 1210 Pfam PF13116 Protein of unknown function 498 765 4.3E-41 T 12-10-2018 IPR025263 Domain of unknown function DUF3971 AFE_0549 b068a1fc4c699a3d65be8b3ccc559d50 1210 Pfam PF13502 AsmA-like C-terminal region 999 1183 4.9E-33 T 12-10-2018 IPR032712 AsmA-like, C-terminal AFE_0173 4c9847d276d55e31564ebff489b19ca2 303 Pfam PF05175 Methyltransferase small domain 134 217 4.7E-17 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 AFE_0173 4c9847d276d55e31564ebff489b19ca2 303 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 15 278 1.6E-69 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 AFE_0173 4c9847d276d55e31564ebff489b19ca2 303 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 206 212 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFE_0173 4c9847d276d55e31564ebff489b19ca2 303 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 14 295 7.8E-112 T 12-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 AFE_0173 4c9847d276d55e31564ebff489b19ca2 303 PIRSF PIRSF037167 1 300 3.6E-103 T 12-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 AFE_0173 4c9847d276d55e31564ebff489b19ca2 303 Gene3D G3DSA:3.40.50.150 107 277 2.3E-47 T 12-10-2018 AFE_0173 4c9847d276d55e31564ebff489b19ca2 303 Gene3D G3DSA:1.10.8.10 16 106 1.8E-10 T 12-10-2018 AFE_0173 4c9847d276d55e31564ebff489b19ca2 303 SUPERFAMILY SSF53335 17 272 6.18E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 Pfam PF14450 Cell division protein FtsA 10 184 2.8E-12 T 12-10-2018 AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 Gene3D G3DSA:3.30.1490.110 86 168 9.4E-127 T 12-10-2018 AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 SUPERFAMILY SSF53067 198 377 1.36E-46 T 12-10-2018 AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 Gene3D G3DSA:3.30.420.40 196 351 9.4E-127 T 12-10-2018 AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 SUPERFAMILY SSF53067 7 221 1.14E-59 T 12-10-2018 AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 Pfam PF02491 SHS2 domain inserted in FTSA 84 161 6.2E-32 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 SMART SM00842 9 195 2.1E-100 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 Gene3D G3DSA:3.90.640.10 234 299 9.4E-127 T 12-10-2018 AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 PIRSF PIRSF003101 1 421 3.3E-155 T 12-10-2018 IPR020823 Cell division protein FtsA AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 Pfam PF14450 Cell division protein FtsA 206 373 1.2E-24 T 12-10-2018 AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 Gene3D G3DSA:3.30.420.40 12 370 9.4E-127 T 12-10-2018 AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 8 377 6.4E-144 T 12-10-2018 IPR020823 Cell division protein FtsA AFE_0201 99afc2a0e43b073d8eecd968e5590bb9 422 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 421 31.363 T 12-10-2018 IPR020823 Cell division protein FtsA AFE_2555 b63edaf069ba93fe4e05e59c4321ffe5 228 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 73 84 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_2555 b63edaf069ba93fe4e05e59c4321ffe5 228 Pfam PF13183 4Fe-4S dicluster domain 24 86 1.2E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_2555 b63edaf069ba93fe4e05e59c4321ffe5 228 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 27 38 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_2555 b63edaf069ba93fe4e05e59c4321ffe5 228 SUPERFAMILY SSF46548 16 105 3.66E-15 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_2555 b63edaf069ba93fe4e05e59c4321ffe5 228 Gene3D G3DSA:1.10.1060.10 3 105 6.0E-7 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_3289 08f2bc00689aaf2db484e2835651454d 81 Pfam PF01455 HupF/HypC family 1 66 1.3E-24 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_3289 08f2bc00689aaf2db484e2835651454d 81 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 74 8.8E-22 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_3289 08f2bc00689aaf2db484e2835651454d 81 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 12-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site AFE_3289 08f2bc00689aaf2db484e2835651454d 81 Gene3D G3DSA:2.40.50.970 1 76 5.2E-25 T 12-10-2018 IPR037254 HupF/HypC superfamily AFE_3289 08f2bc00689aaf2db484e2835651454d 81 SUPERFAMILY SSF159127 1 76 3.27E-23 T 12-10-2018 IPR037254 HupF/HypC superfamily AFE_3289 08f2bc00689aaf2db484e2835651454d 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 18 34 3.4E-21 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_3289 08f2bc00689aaf2db484e2835651454d 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 3.4E-21 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_3289 08f2bc00689aaf2db484e2835651454d 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 57 69 3.4E-21 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_3289 08f2bc00689aaf2db484e2835651454d 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 39 55 3.4E-21 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_2900 eb7a80918ee64f268205e869c1fb0122 318 SUPERFAMILY SSF48452 83 157 8.01E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2900 eb7a80918ee64f268205e869c1fb0122 318 Gene3D G3DSA:1.25.40.10 82 151 1.2E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1348 8b7fe51678e092d9e27635b5dd1b77b1 237 Gene3D G3DSA:3.40.50.150 49 132 6.6E-8 T 12-10-2018 AFE_1348 8b7fe51678e092d9e27635b5dd1b77b1 237 SUPERFAMILY SSF53335 48 147 2.73E-10 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2089 21e820214c6cee691b82742ffbde8e5a 253 SUPERFAMILY SSF141523 150 251 4.05E-17 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFE_2089 21e820214c6cee691b82742ffbde8e5a 253 Pfam PF03734 L,D-transpeptidase catalytic domain 150 251 5.7E-8 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFE_2089 21e820214c6cee691b82742ffbde8e5a 253 Gene3D G3DSA:2.40.440.10 144 253 2.2E-15 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFE_2428 25938b44a1466fd203ee90e3251ba657 120 Pfam PF11604 Copper binding periplasmic protein CusF 50 117 8.4E-21 T 12-10-2018 IPR021647 Copper binding periplasmic protein CusF AFE_2428 25938b44a1466fd203ee90e3251ba657 120 Gene3D G3DSA:2.40.50.320 44 118 6.4E-18 T 12-10-2018 AFE_1576 a71ef578907b2e62d85cfe215af8cede 399 Gene3D G3DSA:3.90.220.20 179 377 4.2E-60 T 12-10-2018 AFE_1576 a71ef578907b2e62d85cfe215af8cede 399 Pfam PF01420 Type I restriction modification DNA specificity domain 204 373 1.4E-16 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFE_1576 a71ef578907b2e62d85cfe215af8cede 399 SUPERFAMILY SSF116734 203 399 1.21E-31 T 12-10-2018 AFE_1576 a71ef578907b2e62d85cfe215af8cede 399 SUPERFAMILY SSF116734 3 201 1.8E-25 T 12-10-2018 AFE_1576 a71ef578907b2e62d85cfe215af8cede 399 Gene3D G3DSA:3.90.220.20 3 395 4.2E-60 T 12-10-2018 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 SUPERFAMILY SSF53756 394 629 5.02E-23 T 12-10-2018 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 Gene3D G3DSA:1.25.40.10 180 247 1.5E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 Gene3D G3DSA:1.25.40.10 116 179 1.0E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 SMART SM00028 309 342 60.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 SMART SM00028 207 240 1.5E-6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 SMART SM00028 139 172 1.6E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 SMART SM00028 173 206 0.083 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 SMART SM00028 241 274 14.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 Pfam PF14559 Tetratricopeptide repeat 150 209 2.8E-9 T 12-10-2018 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 Pfam PF14559 Tetratricopeptide repeat 253 315 2.6E-6 T 12-10-2018 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 SUPERFAMILY SSF48452 129 375 1.44E-41 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 Gene3D G3DSA:1.25.40.10 248 383 8.8E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 Pfam PF13374 Tetratricopeptide repeat 210 236 2.1E-4 T 12-10-2018 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 Pfam PF01724 Domain of unknown function DUF29 6 98 2.3E-8 T 12-10-2018 IPR002636 Protein from unkown function DUF29 AFE_2681 6044e7cbcee2e2b33455ceee6fa83ac3 653 Gene3D G3DSA:3.40.50.2000 525 619 2.4E-5 T 12-10-2018 AFE_2083 74e85e3d4b9c229faa9616bc893eb7ed 411 SUPERFAMILY SSF53756 31 396 1.61E-43 T 12-10-2018 AFE_2083 74e85e3d4b9c229faa9616bc893eb7ed 411 Gene3D G3DSA:3.40.50.2000 190 385 8.4E-138 T 12-10-2018 AFE_2083 74e85e3d4b9c229faa9616bc893eb7ed 411 Gene3D G3DSA:3.40.50.2000 5 386 8.4E-138 T 12-10-2018 AFE_2083 74e85e3d4b9c229faa9616bc893eb7ed 411 Pfam PF00534 Glycosyl transferases group 1 211 378 4.3E-22 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_2081 06b8c332109e6f70939444c255d8a4ea 969 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 7 963 3.6E-304 T 12-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 AFE_2081 06b8c332109e6f70939444c255d8a4ea 969 Gene3D G3DSA:3.30.1590.10 97 214 3.6E-21 T 12-10-2018 AFE_2081 06b8c332109e6f70939444c255d8a4ea 969 Pfam PF00128 Alpha amylase, catalytic domain 29 128 1.3E-12 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFE_2081 06b8c332109e6f70939444c255d8a4ea 969 Gene3D G3DSA:3.20.20.80 11 96 3.0E-17 T 12-10-2018 AFE_2081 06b8c332109e6f70939444c255d8a4ea 969 SUPERFAMILY SSF51445 6 861 1.15E-139 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFE_2081 06b8c332109e6f70939444c255d8a4ea 969 SMART SM00642 15 826 9.6E-6 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFE_2081 06b8c332109e6f70939444c255d8a4ea 969 Gene3D G3DSA:3.20.20.80 743 863 2.7E-41 T 12-10-2018 AFE_2081 06b8c332109e6f70939444c255d8a4ea 969 Gene3D G3DSA:3.20.20.80 571 679 5.7E-10 T 12-10-2018 AFE_2081 06b8c332109e6f70939444c255d8a4ea 969 Gene3D G3DSA:3.20.20.80 289 460 1.9E-34 T 12-10-2018 AFE_1826 eb1f9cd668acf61a4a7cb5f3ab5b3a8c 441 Gene3D G3DSA:3.20.20.140 63 353 1.2E-158 T 12-10-2018 AFE_1826 eb1f9cd668acf61a4a7cb5f3ab5b3a8c 441 SUPERFAMILY SSF51338 5 435 1.23E-28 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_1826 eb1f9cd668acf61a4a7cb5f3ab5b3a8c 441 SUPERFAMILY SSF51556 62 361 9.53E-94 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFE_1826 eb1f9cd668acf61a4a7cb5f3ab5b3a8c 441 Pfam PF01979 Amidohydrolase family 59 407 4.4E-64 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFE_1826 eb1f9cd668acf61a4a7cb5f3ab5b3a8c 441 Gene3D G3DSA:2.30.40.10 17 428 1.2E-158 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 SUPERFAMILY SSF47781 85 142 2.67E-5 T 12-10-2018 IPR010994 RuvA domain 2-like AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 Pfam PF14520 Helix-hairpin-helix domain 94 142 7.5E-4 T 12-10-2018 AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 Pfam PF14490 Helix-hairpin-helix containing domain 145 241 4.4E-26 T 12-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 Pfam PF13604 AAA domain 323 495 5.7E-42 T 12-10-2018 AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 8 709 8.8E-179 T 12-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 Gene3D G3DSA:2.30.30.940 566 636 2.1E-130 T 12-10-2018 AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 SUPERFAMILY SSF52540 194 478 1.76E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 SMART SM00382 334 474 0.0018 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 SUPERFAMILY SSF52540 429 696 1.15E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 Pfam PF13538 UvrD-like helicase C-terminal domain 635 683 9.6E-17 T 12-10-2018 IPR027785 UvrD-like helicase C-terminal domain AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 Gene3D G3DSA:3.40.50.300 322 705 2.1E-130 T 12-10-2018 AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 Gene3D G3DSA:3.40.50.300 478 699 2.1E-130 T 12-10-2018 AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 4 708 24.735 T 12-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 AFE_1047 35ae17ee7c6f5f6f881e3ecbc899ba55 711 Gene3D G3DSA:1.10.10.2220 193 288 1.8E-13 T 12-10-2018 AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 Hamap MF_00900 GTPase HflX [hflX]. 24 386 47.157 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 Gene3D G3DSA:3.40.50.300 194 362 1.4E-39 T 12-10-2018 AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 Pfam PF01926 50S ribosome-binding GTPase 197 315 2.1E-20 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 PIRSF PIRSF006809 2 415 7.0E-135 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 SUPERFAMILY SSF52540 195 358 4.31E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 Pfam PF16360 GTP-binding GTPase Middle Region 111 189 2.2E-27 T 12-10-2018 IPR032305 GTP-binding protein, middle domain AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 7 356 2.9E-140 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 Pfam PF13167 GTP-binding GTPase N-terminal 25 109 7.5E-25 T 12-10-2018 IPR025121 GTPase HflX, N-terminal AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 236 1.9E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 197 217 1.9E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 264 282 1.9E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_1885 f7729ff74ba06b1cf619ffa32e5218e5 432 Gene3D G3DSA:3.40.50.11060 20 135 1.8E-31 T 12-10-2018 AFE_1474 51a1c3685041fc68f1a779bad2ecfbe3 206 Gene3D G3DSA:3.40.30.10 5 201 1.0E-58 T 12-10-2018 AFE_1474 51a1c3685041fc68f1a779bad2ecfbe3 206 SUPERFAMILY SSF52833 2 86 1.5E-21 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1474 51a1c3685041fc68f1a779bad2ecfbe3 206 Pfam PF13417 Glutathione S-transferase, N-terminal domain 14 80 5.3E-9 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFE_1474 51a1c3685041fc68f1a779bad2ecfbe3 206 SUPERFAMILY SSF47616 82 203 3.2E-18 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily AFE_1474 51a1c3685041fc68f1a779bad2ecfbe3 206 Gene3D G3DSA:1.20.1050.10 85 193 1.0E-58 T 12-10-2018 AFE_2829 a267d14a5e2be6eb045159ed04f7768d 269 Gene3D G3DSA:3.30.420.10 4 214 7.1E-19 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_2829 a267d14a5e2be6eb045159ed04f7768d 269 SUPERFAMILY SSF53098 42 219 5.04E-34 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_2829 a267d14a5e2be6eb045159ed04f7768d 269 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 49 257 2.7E-80 T 12-10-2018 IPR019288 Predicted 3'-5' exonuclease, PolB-like AFE_0714 4c5876a750202fe5567efb832c0080a9 231 Gene3D G3DSA:3.40.50.10490 22 217 5.6E-56 T 12-10-2018 AFE_0714 4c5876a750202fe5567efb832c0080a9 231 Pfam PF13580 SIS domain 35 167 9.8E-21 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFE_0714 4c5876a750202fe5567efb832c0080a9 231 SUPERFAMILY SSF53697 29 210 4.85E-39 T 12-10-2018 AFE_2751 79769d0c7d5baee9a80fdfbfef6aedc8 301 Gene3D G3DSA:3.30.70.3040 47 157 4.0E-9 T 12-10-2018 AFE_2751 79769d0c7d5baee9a80fdfbfef6aedc8 301 PIRSF PIRSF003097 5 298 9.4E-68 T 12-10-2018 IPR004513 Cell division protein FtsX GO:0016021 AFE_0154 98f0159dadcad961e4b6119c9ca54c8d 218 PRINTS PR00783 Major intrinsic protein family signature 76 95 4.2E-38 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFE_0154 98f0159dadcad961e4b6119c9ca54c8d 218 PRINTS PR00783 Major intrinsic protein family signature 154 176 4.2E-38 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFE_0154 98f0159dadcad961e4b6119c9ca54c8d 218 PRINTS PR00783 Major intrinsic protein family signature 6 25 4.2E-38 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFE_0154 98f0159dadcad961e4b6119c9ca54c8d 218 PRINTS PR00783 Major intrinsic protein family signature 191 211 4.2E-38 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFE_0154 98f0159dadcad961e4b6119c9ca54c8d 218 PRINTS PR00783 Major intrinsic protein family signature 124 142 4.2E-38 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFE_0154 98f0159dadcad961e4b6119c9ca54c8d 218 PRINTS PR00783 Major intrinsic protein family signature 39 63 4.2E-38 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFE_0154 98f0159dadcad961e4b6119c9ca54c8d 218 Pfam PF00230 Major intrinsic protein 4 208 2.7E-41 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AFE_0154 98f0159dadcad961e4b6119c9ca54c8d 218 Gene3D G3DSA:1.20.1080.10 1 218 1.4E-56 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFE_0154 98f0159dadcad961e4b6119c9ca54c8d 218 SUPERFAMILY SSF81338 4 213 2.62E-52 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFE_0151 fcbe68b629365bd91cc28d51eb858c3d 132 Pfam PF00581 Rhodanese-like domain 20 108 3.4E-8 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_0151 fcbe68b629365bd91cc28d51eb858c3d 132 SMART SM00450 9 115 8.4E-12 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_0151 fcbe68b629365bd91cc28d51eb858c3d 132 SUPERFAMILY SSF52821 7 131 4.98E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_0151 fcbe68b629365bd91cc28d51eb858c3d 132 Gene3D G3DSA:3.40.250.10 5 131 1.4E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 10 583 2.3E-169 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 602 26.779 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 Gene3D G3DSA:3.40.1440.10 8 102 1.0E-31 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 SUPERFAMILY SSF47781 517 604 1.49E-21 T 12-10-2018 IPR010994 RuvA domain 2-like AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 Pfam PF12826 Helix-hairpin-helix motif 555 605 3.7E-7 T 12-10-2018 AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 381 537 1.4E-47 T 12-10-2018 IPR001162 UvrC family homology region AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 Pfam PF01541 GIY-YIG catalytic domain 18 93 1.2E-10 T 12-10-2018 IPR000305 GIY-YIG endonuclease AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 SMART SM00278 551 570 6.1 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 SMART SM00278 583 602 160.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 SMART SM00465 17 98 1.5E-19 T 12-10-2018 IPR000305 GIY-YIG endonuclease AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 Gene3D G3DSA:3.30.420.340 377 537 1.4E-45 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 Gene3D G3DSA:4.10.860.10 196 241 3.0E-5 T 12-10-2018 AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 Gene3D G3DSA:1.10.150.20 541 603 1.1E-19 T 12-10-2018 AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 SUPERFAMILY SSF82771 17 100 2.75E-21 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 SUPERFAMILY SSF46600 191 243 9.68E-14 T 12-10-2018 IPR036876 UVR domain superfamily AFE_0853 a98e78ce8b4cfdbe0d67f2c2c6d3578a 608 Pfam PF02151 UvrB/uvrC motif 205 238 2.6E-7 T 12-10-2018 IPR001943 UVR domain GO:0005515 AFE_0011 c932e607d84f5b1fc94aed92c6270999 83 SUPERFAMILY SSF55229 33 82 7.72E-14 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 AFE_0011 c932e607d84f5b1fc94aed92c6270999 83 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 82 18.123 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 AFE_0011 c932e607d84f5b1fc94aed92c6270999 83 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 80 1.6E-28 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 AFE_0011 c932e607d84f5b1fc94aed92c6270999 83 Pfam PF03776 Septum formation topological specificity factor MinE 14 79 1.3E-24 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 AFE_0011 c932e607d84f5b1fc94aed92c6270999 83 Gene3D G3DSA:3.30.1070.10 1 81 1.1E-26 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 AFE_2957 149f5980b32796099fab3762d6679b85 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 2.8E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2957 149f5980b32796099fab3762d6679b85 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 2.8E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2957 149f5980b32796099fab3762d6679b85 506 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 471 2.8E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2957 149f5980b32796099fab3762d6679b85 506 SUPERFAMILY SSF158472 198 245 3.4E-5 T 12-10-2018 AFE_2957 149f5980b32796099fab3762d6679b85 506 Gene3D G3DSA:3.30.565.10 324 477 1.1E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2957 149f5980b32796099fab3762d6679b85 506 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 317 2.0E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_2957 149f5980b32796099fab3762d6679b85 506 SUPERFAMILY SSF47384 235 316 2.75E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_2957 149f5980b32796099fab3762d6679b85 506 SMART SM00387 362 474 1.5E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2957 149f5980b32796099fab3762d6679b85 506 Gene3D G3DSA:1.20.1480.50 157 248 6.3E-7 T 12-10-2018 AFE_2957 149f5980b32796099fab3762d6679b85 506 SMART SM00304 197 249 8.2E-5 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFE_2957 149f5980b32796099fab3762d6679b85 506 SMART SM00388 250 318 6.3E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_2957 149f5980b32796099fab3762d6679b85 506 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 473 9.3E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2957 149f5980b32796099fab3762d6679b85 506 Gene3D G3DSA:1.10.287.130 249 317 4.2E-15 T 12-10-2018 AFE_2957 149f5980b32796099fab3762d6679b85 506 SUPERFAMILY SSF55874 307 472 9.43E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 PIRSF PIRSF005814 8 774 2.3E-157 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 SUPERFAMILY SSF160443 697 770 3.27E-7 T 12-10-2018 IPR036063 Smr domain superfamily AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 Gene3D G3DSA:3.30.1370.110 691 774 5.5E-17 T 12-10-2018 AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 SMART SM00463 696 774 1.3E-11 T 12-10-2018 IPR002625 Smr domain AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 SMART SM00533 17 318 9.3E-6 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 SMART SM00534 334 517 3.6E-44 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 SUPERFAMILY SSF48334 34 283 3.53E-18 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 SUPERFAMILY SSF52540 296 518 2.98E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 Pfam PF01713 Smr domain 699 773 2.0E-13 T 12-10-2018 IPR002625 Smr domain AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 Gene3D G3DSA:3.40.50.300 297 602 8.2E-65 T 12-10-2018 AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 Pfam PF00488 MutS domain V 337 515 2.5E-30 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFE_2338 96f5de7d833ee4bf18b606d8c4cc0574 774 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 10 773 17.906 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 AFE_1457 9b1cf70e90b7944646049aa190fb4dc1 313 SUPERFAMILY SSF51735 4 131 1.75E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1457 9b1cf70e90b7944646049aa190fb4dc1 313 Gene3D G3DSA:3.30.360.10 119 301 8.9E-63 T 12-10-2018 AFE_1457 9b1cf70e90b7944646049aa190fb4dc1 313 Gene3D G3DSA:3.40.50.720 5 288 8.9E-63 T 12-10-2018 AFE_1457 9b1cf70e90b7944646049aa190fb4dc1 313 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 118 5.8E-26 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFE_1457 9b1cf70e90b7944646049aa190fb4dc1 313 SUPERFAMILY SSF55347 124 275 1.83E-14 T 12-10-2018 AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 Gene3D G3DSA:1.10.10.760 447 491 2.0E-179 T 12-10-2018 AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 SMART SM00642 93 479 9.2E-10 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 7 71 1.3E-7 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 PIRSF PIRSF006337 4 589 9.6E-215 T 12-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 Pfam PF11941 Domain of unknown function (DUF3459) 510 598 1.3E-15 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 SUPERFAMILY SSF51445 94 520 1.77E-106 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 Pfam PF00128 Alpha amylase, catalytic domain 128 215 2.5E-15 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 SUPERFAMILY SSF81296 4 96 6.2E-19 T 12-10-2018 IPR014756 Immunoglobulin E-set AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 Gene3D G3DSA:3.20.20.80 106 519 2.0E-179 T 12-10-2018 AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 Gene3D G3DSA:2.60.40.10 5 102 7.3E-23 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFE_2082 667be2c7da4372f90da590fa7ad7d652 618 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 19 567 2.0E-207 T 12-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 AFE_0957 61e0a721b4506b32b17c551528ed01aa 451 Gene3D G3DSA:3.40.50.300 123 300 2.6E-63 T 12-10-2018 AFE_0957 61e0a721b4506b32b17c551528ed01aa 451 Gene3D G3DSA:1.10.10.60 395 439 1.5E-9 T 12-10-2018 AFE_0957 61e0a721b4506b32b17c551528ed01aa 451 Pfam PF00158 Sigma-54 interaction domain 130 296 3.1E-65 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_0957 61e0a721b4506b32b17c551528ed01aa 451 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216 231 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFE_0957 61e0a721b4506b32b17c551528ed01aa 451 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 340 349 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_0957 61e0a721b4506b32b17c551528ed01aa 451 SUPERFAMILY SSF46689 341 440 4.3E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_0957 61e0a721b4506b32b17c551528ed01aa 451 Gene3D G3DSA:1.10.8.60 301 377 2.6E-18 T 12-10-2018 AFE_0957 61e0a721b4506b32b17c551528ed01aa 451 SMART SM00382 150 293 1.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0957 61e0a721b4506b32b17c551528ed01aa 451 SUPERFAMILY SSF52540 130 370 1.69E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0373 5019599e75a74a8ecf6b837536b30ac7 158 SUPERFAMILY SSF46955 6 131 6.59E-36 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFE_0373 5019599e75a74a8ecf6b837536b30ac7 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 1.1E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_0373 5019599e75a74a8ecf6b837536b30ac7 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 1.1E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_0373 5019599e75a74a8ecf6b837536b30ac7 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 1.1E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_0373 5019599e75a74a8ecf6b837536b30ac7 158 Gene3D G3DSA:1.10.1660.10 1 130 1.1E-36 T 12-10-2018 AFE_0373 5019599e75a74a8ecf6b837536b30ac7 158 ProSitePatterns PS00552 MerR-type HTH domain signature. 8 30 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_0373 5019599e75a74a8ecf6b837536b30ac7 158 SMART SM00422 5 74 2.0E-29 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_0373 5019599e75a74a8ecf6b837536b30ac7 158 Pfam PF00376 MerR family regulatory protein 6 43 2.6E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_0373 5019599e75a74a8ecf6b837536b30ac7 158 Pfam PF09278 MerR, DNA binding 49 111 9.2E-19 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding AFE_3092 334dacfd2b07bbffc1874022e463c984 228 Gene3D G3DSA:3.40.50.300 14 213 6.3E-49 T 12-10-2018 AFE_3092 334dacfd2b07bbffc1874022e463c984 228 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 18 199 2.9E-64 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 AFE_3092 334dacfd2b07bbffc1874022e463c984 228 SUPERFAMILY SSF52540 25 203 6.47E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3092 334dacfd2b07bbffc1874022e463c984 228 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 22 203 26.187 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 AFE_3092 334dacfd2b07bbffc1874022e463c984 228 Pfam PF01926 50S ribosome-binding GTPase 36 154 1.2E-18 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_2746 b255222b2e73a83c044991a24b8525a4 314 Pfam PF00589 Phage integrase family 112 286 2.8E-39 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_2746 b255222b2e73a83c044991a24b8525a4 314 SUPERFAMILY SSF47823 6 97 1.49E-12 T 12-10-2018 AFE_2746 b255222b2e73a83c044991a24b8525a4 314 Gene3D G3DSA:1.10.150.130 1 109 6.4E-16 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFE_2746 b255222b2e73a83c044991a24b8525a4 314 SUPERFAMILY SSF56349 106 298 5.0E-50 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_2746 b255222b2e73a83c044991a24b8525a4 314 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 300 49.434 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD AFE_2746 b255222b2e73a83c044991a24b8525a4 314 Gene3D G3DSA:1.10.443.10 113 294 7.3E-54 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_2746 b255222b2e73a83c044991a24b8525a4 314 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 86 2.6E-14 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFE_0088 a98c72d21cfb7213ae03f45ca01bfd33 91 SUPERFAMILY SSF143011 4 90 1.94E-6 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFE_0088 a98c72d21cfb7213ae03f45ca01bfd33 91 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 4 88 3.9E-17 T 12-10-2018 IPR007711 Toxin HigB-1 AFE_0088 a98c72d21cfb7213ae03f45ca01bfd33 91 Gene3D G3DSA:3.30.2310.20 1 91 6.8E-28 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFE_0465 b68dc67ec3fe5224a218701353dbb1a3 391 Pfam PF01545 Cation efflux family 21 210 2.0E-48 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFE_0465 b68dc67ec3fe5224a218701353dbb1a3 391 Gene3D G3DSA:1.20.1510.10 14 211 3.7E-62 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFE_0465 b68dc67ec3fe5224a218701353dbb1a3 391 Gene3D G3DSA:3.30.70.1350 212 294 3.8E-18 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFE_0465 b68dc67ec3fe5224a218701353dbb1a3 391 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 15 294 4.4E-71 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFE_0465 b68dc67ec3fe5224a218701353dbb1a3 391 SUPERFAMILY SSF161111 12 212 3.53E-56 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFE_0465 b68dc67ec3fe5224a218701353dbb1a3 391 SUPERFAMILY SSF160240 215 294 3.92E-18 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFE_0465 b68dc67ec3fe5224a218701353dbb1a3 391 Pfam PF16916 Dimerisation domain of Zinc Transporter 217 291 8.2E-21 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain AFE_2301 4fe99c58cb3f70a910ae313570c64edd 242 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 161 222 4.8E-16 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 AFE_2301 4fe99c58cb3f70a910ae313570c64edd 242 PRINTS PR01374 Gram-negative bacterial tonB protein signature 76 86 1.8E-5 T 12-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 AFE_2301 4fe99c58cb3f70a910ae313570c64edd 242 PRINTS PR01374 Gram-negative bacterial tonB protein signature 156 177 1.8E-5 T 12-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 AFE_2301 4fe99c58cb3f70a910ae313570c64edd 242 PRINTS PR01374 Gram-negative bacterial tonB protein signature 177 195 1.8E-5 T 12-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 AFE_2301 4fe99c58cb3f70a910ae313570c64edd 242 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 163 240 7.8E-17 T 12-10-2018 IPR006260 TonB/TolA, C-terminal AFE_2301 4fe99c58cb3f70a910ae313570c64edd 242 SUPERFAMILY SSF74653 159 219 2.09E-15 T 12-10-2018 AFE_2301 4fe99c58cb3f70a910ae313570c64edd 242 Gene3D G3DSA:3.30.1150.10 94 241 3.8E-24 T 12-10-2018 AFE_1513 b06b51fe2ae2b2a85eaf9245451f70f8 87 Pfam PF05082 Rop-like 24 83 8.3E-27 T 12-10-2018 IPR007774 Putative nitrogen fixation protein AFE_1513 b06b51fe2ae2b2a85eaf9245451f70f8 87 Gene3D G3DSA:1.10.287.660 21 85 1.3E-27 T 12-10-2018 IPR029012 Helix hairpin bin domain superfamily AFE_1513 b06b51fe2ae2b2a85eaf9245451f70f8 87 PIRSF PIRSF037676 5 85 1.0E-24 T 12-10-2018 IPR007774 Putative nitrogen fixation protein AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 8 508 7.8E-146 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 Pfam PF03023 MviN-like protein 31 468 1.7E-140 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 6 501 20.195 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 PRINTS PR01806 Virulence factor MviN signature 359 378 1.6E-76 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 PRINTS PR01806 Virulence factor MviN signature 55 71 1.6E-76 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 PRINTS PR01806 Virulence factor MviN signature 36 55 1.6E-76 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 PRINTS PR01806 Virulence factor MviN signature 136 160 1.6E-76 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 PRINTS PR01806 Virulence factor MviN signature 262 288 1.6E-76 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 PRINTS PR01806 Virulence factor MviN signature 160 181 1.6E-76 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 PRINTS PR01806 Virulence factor MviN signature 411 428 1.6E-76 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_0559 c8f520da6f7cc1aec5c6fbea931b02bd 517 PIRSF PIRSF002869 3 513 6.8E-160 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ AFE_2546 1b698a3f69d6e1481b54aa626b3b88dd 377 Pfam PF04055 Radical SAM superfamily 78 221 1.9E-9 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_2546 1b698a3f69d6e1481b54aa626b3b88dd 377 SUPERFAMILY SSF102114 69 311 1.2E-17 T 12-10-2018 AFE_2546 1b698a3f69d6e1481b54aa626b3b88dd 377 SMART SM00729 69 273 0.0014 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFE_2546 1b698a3f69d6e1481b54aa626b3b88dd 377 Gene3D G3DSA:3.20.20.70 52 327 7.9E-9 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_3213 099ca4379469543d75e8a260dbb1d95e 221 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 37 191 3.3E-42 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFE_3213 099ca4379469543d75e8a260dbb1d95e 221 Gene3D G3DSA:3.40.50.150 2 215 2.1E-54 T 12-10-2018 AFE_3213 099ca4379469543d75e8a260dbb1d95e 221 SUPERFAMILY SSF53335 25 192 1.52E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_3213 099ca4379469543d75e8a260dbb1d95e 221 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 25 213 24.832 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFE_3213 099ca4379469543d75e8a260dbb1d95e 221 Pfam PF02527 rRNA small subunit methyltransferase G 34 195 2.3E-45 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFE_1969 6e62d0edac568c764d431e49bd86a86f 655 Gene3D G3DSA:3.30.300.30 526 654 4.9E-29 T 12-10-2018 AFE_1969 6e62d0edac568c764d431e49bd86a86f 655 Pfam PF00501 AMP-binding enzyme 96 530 1.3E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFE_1969 6e62d0edac568c764d431e49bd86a86f 655 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 34 87 1.1E-19 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AFE_1969 6e62d0edac568c764d431e49bd86a86f 655 Pfam PF13193 AMP-binding enzyme C-terminal domain 539 619 5.9E-27 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFE_1969 6e62d0edac568c764d431e49bd86a86f 655 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 28 650 7.6E-298 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 AFE_1969 6e62d0edac568c764d431e49bd86a86f 655 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFE_1969 6e62d0edac568c764d431e49bd86a86f 655 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 10 654 52.158 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 AFE_1969 6e62d0edac568c764d431e49bd86a86f 655 Gene3D G3DSA:3.40.50.12780 63 523 2.3E-112 T 12-10-2018 AFE_1969 6e62d0edac568c764d431e49bd86a86f 655 SUPERFAMILY SSF56801 22 632 2.75E-179 T 12-10-2018 AFE_2739 0ff8f3d167974c3f2c18cd1dfbcbb613 201 SUPERFAMILY SSF53335 7 150 9.22E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2739 0ff8f3d167974c3f2c18cd1dfbcbb613 201 Pfam PF08241 Methyltransferase domain 47 133 1.1E-17 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFE_2739 0ff8f3d167974c3f2c18cd1dfbcbb613 201 Gene3D G3DSA:3.40.50.150 27 174 2.4E-28 T 12-10-2018 AFE_0544 3ea4fd4203db0592bb2ba259fe76a6bd 276 Pfam PF12146 Serine aminopeptidase, S33 56 162 2.3E-14 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 AFE_0544 3ea4fd4203db0592bb2ba259fe76a6bd 276 SUPERFAMILY SSF53474 31 256 1.08E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_0544 3ea4fd4203db0592bb2ba259fe76a6bd 276 Gene3D G3DSA:3.40.50.1820 32 265 5.2E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_1460 6c4dd4daec6141c3214d8178c1e2d6b9 196 SUPERFAMILY SSF53098 11 194 3.64E-63 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_1460 6c4dd4daec6141c3214d8178c1e2d6b9 196 Gene3D G3DSA:3.30.420.10 3 196 2.2E-64 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_1460 6c4dd4daec6141c3214d8178c1e2d6b9 196 Hamap MF_00052_B Ribonuclease HII [rnhB]. 13 189 33.029 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 AFE_1460 6c4dd4daec6141c3214d8178c1e2d6b9 196 Pfam PF01351 Ribonuclease HII 15 186 1.2E-29 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain AFE_2912 52184c22bd4fd5367b327605b3ccc46f 434 Pfam PF04285 Protein of unknown function (DUF444) 4 428 3.7E-140 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 AFE_2912 52184c22bd4fd5367b327605b3ccc46f 434 SUPERFAMILY SSF53300 260 395 2.45E-5 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_0655 6b0df66abbc868ec0d2a611e9b7ae992 224 SMART SM00382 32 220 1.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0655 6b0df66abbc868ec0d2a611e9b7ae992 224 Pfam PF00005 ABC transporter 24 171 4.5E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0655 6b0df66abbc868ec0d2a611e9b7ae992 224 Gene3D G3DSA:3.40.50.300 2 220 6.1E-60 T 12-10-2018 AFE_0655 6b0df66abbc868ec0d2a611e9b7ae992 224 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_0655 6b0df66abbc868ec0d2a611e9b7ae992 224 SUPERFAMILY SSF52540 5 214 1.46E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1794 22a88286a44aa274f7a6cf8d79cfe6a5 223 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 175 3.0E-15 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFE_1794 22a88286a44aa274f7a6cf8d79cfe6a5 223 PIRSF PIRSF001435 2 222 9.5E-65 T 12-10-2018 AFE_1794 22a88286a44aa274f7a6cf8d79cfe6a5 223 SMART SM00478 38 200 5.9E-26 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFE_1794 22a88286a44aa274f7a6cf8d79cfe6a5 223 Gene3D G3DSA:1.10.340.30 21 139 1.6E-35 T 12-10-2018 AFE_1794 22a88286a44aa274f7a6cf8d79cfe6a5 223 SUPERFAMILY SSF48150 9 219 3.14E-51 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFE_1794 22a88286a44aa274f7a6cf8d79cfe6a5 223 Gene3D G3DSA:1.10.1670.10 140 223 5.8E-14 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFE_1203 62c5b7764455e3ac9065eadddf260b3e 552 SUPERFAMILY SSF52540 121 343 3.92E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1203 62c5b7764455e3ac9065eadddf260b3e 552 Pfam PF13401 AAA domain 121 269 2.6E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1203 62c5b7764455e3ac9065eadddf260b3e 552 Gene3D G3DSA:3.40.50.300 112 279 8.3E-7 T 12-10-2018 AFE_1323 8dcfe5ee28b8d1647403c83c6e00771d 313 SUPERFAMILY SSF53067 166 312 2.14E-11 T 12-10-2018 AFE_1323 8dcfe5ee28b8d1647403c83c6e00771d 313 SUPERFAMILY SSF53067 1 151 1.42E-12 T 12-10-2018 AFE_1323 8dcfe5ee28b8d1647403c83c6e00771d 313 Gene3D G3DSA:3.30.420.40 166 294 3.1E-16 T 12-10-2018 AFE_1323 8dcfe5ee28b8d1647403c83c6e00771d 313 Gene3D G3DSA:3.30.420.40 3 165 1.0E-8 T 12-10-2018 AFE_2513 1cf617b49581fb16c4809519ce3e903f 174 SUPERFAMILY SSF81901 34 122 2.09E-14 T 12-10-2018 AFE_2513 1cf617b49581fb16c4809519ce3e903f 174 Gene3D G3DSA:1.25.40.10 21 145 4.6E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2513 1cf617b49581fb16c4809519ce3e903f 174 Pfam PF08238 Sel1 repeat 76 89 0.039 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2513 1cf617b49581fb16c4809519ce3e903f 174 Pfam PF08238 Sel1 repeat 91 122 0.0011 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2513 1cf617b49581fb16c4809519ce3e903f 174 SMART SM00671 49 89 26.0 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2513 1cf617b49581fb16c4809519ce3e903f 174 SMART SM00671 90 125 2.2 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2923 890a37c7b570c3070c36f59ca31fe9b0 389 Gene3D G3DSA:2.60.410.10 283 373 2.0E-9 T 12-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_2923 890a37c7b570c3070c36f59ca31fe9b0 389 SMART SM00936 283 374 1.8E-8 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_2923 890a37c7b570c3070c36f59ca31fe9b0 389 SUPERFAMILY SSF56601 5 282 1.39E-54 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_2923 890a37c7b570c3070c36f59ca31fe9b0 389 Gene3D G3DSA:3.40.710.10 36 281 8.6E-64 T 12-10-2018 AFE_2923 890a37c7b570c3070c36f59ca31fe9b0 389 SUPERFAMILY SSF69189 284 376 5.69E-9 T 12-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_2923 890a37c7b570c3070c36f59ca31fe9b0 389 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 46 263 3.4E-53 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 AFE_2923 890a37c7b570c3070c36f59ca31fe9b0 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 8.2E-13 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFE_2923 890a37c7b570c3070c36f59ca31fe9b0 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 8.2E-13 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFE_2923 890a37c7b570c3070c36f59ca31fe9b0 389 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 71 82 8.2E-13 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFE_2923 890a37c7b570c3070c36f59ca31fe9b0 389 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 283 373 9.1E-7 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 5 485 79.206 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 SUPERFAMILY SSF55347 176 485 3.92E-111 T 12-10-2018 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 5 485 6.0E-176 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 Gene3D G3DSA:3.40.50.720 8 433 6.0E-173 T 12-10-2018 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 PIRSF PIRSF000110 1 487 5.4E-182 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 142 155 2.9E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 236 252 2.9E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 327 353 2.9E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 166 194 2.9E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 218 235 2.9E-49 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 9 186 9.5E-58 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 188 484 1.0E-112 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 176 182 - T 12-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 SUPERFAMILY SSF51735 5 189 6.3E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2025 ae697c19fcbcb2d5f0d1246650068854 487 Gene3D G3DSA:3.30.360.10 176 474 6.0E-173 T 12-10-2018 AFE_2064 49302d189b319830735a1768df4eb8bc 475 Pfam PF00156 Phosphoribosyl transferase domain 276 389 7.8E-10 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFE_2064 49302d189b319830735a1768df4eb8bc 475 PIRSF PIRSF000485 10 469 4.8E-167 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFE_2064 49302d189b319830735a1768df4eb8bc 475 Gene3D G3DSA:3.40.50.2020 274 438 5.9E-157 T 12-10-2018 AFE_2064 49302d189b319830735a1768df4eb8bc 475 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 13 455 47.017 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFE_2064 49302d189b319830735a1768df4eb8bc 475 Pfam PF13537 Glutamine amidotransferase domain 95 212 4.1E-20 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFE_2064 49302d189b319830735a1768df4eb8bc 475 Gene3D G3DSA:3.60.20.10 14 456 5.9E-157 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_2064 49302d189b319830735a1768df4eb8bc 475 SUPERFAMILY SSF56235 14 256 2.66E-67 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_2064 49302d189b319830735a1768df4eb8bc 475 SUPERFAMILY SSF53271 250 463 2.88E-71 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFE_2064 49302d189b319830735a1768df4eb8bc 475 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 14 456 6.4E-159 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFE_0914 0011d1180387c56a7aabfa3241127b7a 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AFE_0914 0011d1180387c56a7aabfa3241127b7a 90 SUPERFAMILY SSF47729 1 90 3.53E-32 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_0914 0011d1180387c56a7aabfa3241127b7a 90 SMART SM00411 1 90 1.4E-40 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_0914 0011d1180387c56a7aabfa3241127b7a 90 Gene3D G3DSA:4.10.520.10 1 90 5.9E-35 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_0914 0011d1180387c56a7aabfa3241127b7a 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.0E-32 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_0914 0011d1180387c56a7aabfa3241127b7a 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.2E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_0914 0011d1180387c56a7aabfa3241127b7a 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.2E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_0914 0011d1180387c56a7aabfa3241127b7a 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.2E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_0424 d92ae78a7fb3d99129b688e3299cb35c 428 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 427 6.9E-193 T 12-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 AFE_0424 d92ae78a7fb3d99129b688e3299cb35c 428 Gene3D G3DSA:3.40.718.10 1 428 1.5E-175 T 12-10-2018 AFE_0424 d92ae78a7fb3d99129b688e3299cb35c 428 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 28 421 2.4E-105 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFE_0424 d92ae78a7fb3d99129b688e3299cb35c 428 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 315 334 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFE_0424 d92ae78a7fb3d99129b688e3299cb35c 428 SUPERFAMILY SSF53659 3 428 2.7E-134 T 12-10-2018 AFE_0424 d92ae78a7fb3d99129b688e3299cb35c 428 SMART SM01329 27 424 3.9E-170 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFE_2052 89b3f7474b695d7b5b164a7226ba2c52 349 Pfam PF00892 EamA-like transporter family 10 144 4.0E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFE_2052 89b3f7474b695d7b5b164a7226ba2c52 349 SUPERFAMILY SSF103481 54 148 4.05E-11 T 12-10-2018 AFE_2052 89b3f7474b695d7b5b164a7226ba2c52 349 SUPERFAMILY SSF103481 198 288 3.66E-6 T 12-10-2018 AFE_1405 83975f12976b6f171c56942571ab75c2 440 Gene3D G3DSA:3.40.50.720 1 202 2.0E-77 T 12-10-2018 AFE_1405 83975f12976b6f171c56942571ab75c2 440 SUPERFAMILY SSF51735 1 195 1.51E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1405 83975f12976b6f171c56942571ab75c2 440 PIRSF PIRSF500134 1 440 5.0E-186 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFE_1405 83975f12976b6f171c56942571ab75c2 440 Gene3D G3DSA:1.20.5.100 204 234 1.9E-15 T 12-10-2018 AFE_1405 83975f12976b6f171c56942571ab75c2 440 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 424 5.7E-33 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_1405 83975f12976b6f171c56942571ab75c2 440 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 185 1.8E-62 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_1405 83975f12976b6f171c56942571ab75c2 440 SMART SM00984 320 424 2.0E-55 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_1405 83975f12976b6f171c56942571ab75c2 440 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 296 7.1E-37 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_1405 83975f12976b6f171c56942571ab75c2 440 SUPERFAMILY SSF48179 204 300 2.24E-33 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFE_1405 83975f12976b6f171c56942571ab75c2 440 Gene3D G3DSA:3.40.50.720 235 440 1.0E-83 T 12-10-2018 AFE_1405 83975f12976b6f171c56942571ab75c2 440 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 420 2.5E-136 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFE_1405 83975f12976b6f171c56942571ab75c2 440 SUPERFAMILY SSF52413 306 434 3.4E-42 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFE_1405 83975f12976b6f171c56942571ab75c2 440 PIRSF PIRSF000124 1 439 2.4E-150 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFE_0206 351d979ac7049b30653603ca24a23862 360 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 355 35.904 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_0206 351d979ac7049b30653603ca24a23862 360 Gene3D G3DSA:3.40.50.2000 160 339 5.3E-116 T 12-10-2018 AFE_0206 351d979ac7049b30653603ca24a23862 360 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 142 6.2E-41 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_0206 351d979ac7049b30653603ca24a23862 360 SUPERFAMILY SSF53756 4 355 4.35E-115 T 12-10-2018 AFE_0206 351d979ac7049b30653603ca24a23862 360 Gene3D G3DSA:3.40.50.2000 6 345 5.3E-116 T 12-10-2018 AFE_0206 351d979ac7049b30653603ca24a23862 360 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 183 342 6.6E-35 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 AFE_0206 351d979ac7049b30653603ca24a23862 360 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4 350 3.9E-105 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_0592 5b62bbb5cbec28bc1bda3fd2bcaa9bd2 300 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 6 288 27.84 T 12-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 AFE_0592 5b62bbb5cbec28bc1bda3fd2bcaa9bd2 300 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 68 90 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site AFE_0592 5b62bbb5cbec28bc1bda3fd2bcaa9bd2 300 Pfam PF01040 UbiA prenyltransferase family 29 273 6.1E-62 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFE_0592 5b62bbb5cbec28bc1bda3fd2bcaa9bd2 300 Gene3D G3DSA:1.20.120.1780 170 288 1.2E-13 T 12-10-2018 AFE_0592 5b62bbb5cbec28bc1bda3fd2bcaa9bd2 300 Gene3D G3DSA:1.10.357.140 24 169 2.0E-38 T 12-10-2018 AFE_0592 5b62bbb5cbec28bc1bda3fd2bcaa9bd2 300 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 11 287 9.8E-98 T 12-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 AFE_2240 8825f87bad00318bd3afa541f1867617 132 Pfam PF00543 Nitrogen regulatory protein P-II 4 114 1.0E-30 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2240 8825f87bad00318bd3afa541f1867617 132 PRINTS PR00340 P-II protein signature 92 112 7.0E-26 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2240 8825f87bad00318bd3afa541f1867617 132 PRINTS PR00340 P-II protein signature 23 41 7.0E-26 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2240 8825f87bad00318bd3afa541f1867617 132 PRINTS PR00340 P-II protein signature 2 17 7.0E-26 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2240 8825f87bad00318bd3afa541f1867617 132 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 12-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 AFE_2240 8825f87bad00318bd3afa541f1867617 132 SMART SM00938 4 114 1.7E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_2240 8825f87bad00318bd3afa541f1867617 132 SUPERFAMILY SSF54913 1 118 5.08E-32 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFE_2240 8825f87bad00318bd3afa541f1867617 132 Gene3D G3DSA:3.30.70.120 1 120 5.6E-33 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFE_0165 85e59022b7e9caef8160d16b3880cc99 333 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 35 320 4.3E-104 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 AFE_0165 85e59022b7e9caef8160d16b3880cc99 333 Gene3D G3DSA:3.40.718.10 1 329 8.8E-121 T 12-10-2018 AFE_0165 85e59022b7e9caef8160d16b3880cc99 333 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 4 328 35.497 T 12-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 AFE_0165 85e59022b7e9caef8160d16b3880cc99 333 SUPERFAMILY SSF53659 5 328 7.84E-109 T 12-10-2018 AFE_0165 85e59022b7e9caef8160d16b3880cc99 333 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 324 4.1E-125 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 SMART SM00490 260 341 3.4E-32 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 SMART SM00487 26 224 8.2E-61 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 SUPERFAMILY SSF52540 76 362 1.52E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 Pfam PF03880 DbpA RNA binding domain 491 560 2.3E-18 T 12-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 2 563 43.712 T 12-10-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 Pfam PF00270 DEAD/DEAH box helicase 32 196 1.4E-47 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 Gene3D G3DSA:3.40.50.300 217 450 6.1E-50 T 12-10-2018 AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 Gene3D G3DSA:3.40.50.300 7 213 1.5E-70 T 12-10-2018 AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 Gene3D G3DSA:3.30.70.330 491 564 1.6E-8 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AFE_0589 c03e47733ea60ba4e06fd539e60f5b71 617 Pfam PF00271 Helicase conserved C-terminal domain 233 341 2.5E-28 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_1870 f73dcef918abafa5e7f2df59439be0ff 440 SUPERFAMILY SSF56672 3 200 8.34E-22 T 12-10-2018 AFE_1870 f73dcef918abafa5e7f2df59439be0ff 440 Gene3D G3DSA:3.30.70.270 41 199 4.8E-9 T 12-10-2018 AFE_1870 f73dcef918abafa5e7f2df59439be0ff 440 Gene3D G3DSA:1.10.150.20 144 196 4.8E-9 T 12-10-2018 AFE_1870 f73dcef918abafa5e7f2df59439be0ff 440 Gene3D G3DSA:2.30.40.20 7 40 4.8E-9 T 12-10-2018 AFE_1870 f73dcef918abafa5e7f2df59439be0ff 440 Pfam PF00817 impB/mucB/samB family 5 119 1.9E-5 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFE_0298 10633f66861a2a1c7d10e0d0f5ac8a53 218 Gene3D G3DSA:2.40.30.20 102 198 5.1E-32 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_0298 10633f66861a2a1c7d10e0d0f5ac8a53 218 SUPERFAMILY SSF63380 93 195 1.19E-31 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFE_0298 10633f66861a2a1c7d10e0d0f5ac8a53 218 SUPERFAMILY SSF63380 1 93 7.48E-25 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFE_0298 10633f66861a2a1c7d10e0d0f5ac8a53 218 PIRSF PIRSF000498 1 210 3.6E-72 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0298 10633f66861a2a1c7d10e0d0f5ac8a53 218 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 195 8.8E-61 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0298 10633f66861a2a1c7d10e0d0f5ac8a53 218 Pfam PF00677 Lumazine binding domain 101 184 3.1E-23 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0298 10633f66861a2a1c7d10e0d0f5ac8a53 218 Pfam PF00677 Lumazine binding domain 3 87 7.7E-21 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0298 10633f66861a2a1c7d10e0d0f5ac8a53 218 Gene3D G3DSA:2.40.30.20 1 89 6.1E-27 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFE_1260 8eda4cf7742d0327106650292449fa47 161 Gene3D G3DSA:2.40.50.140 1 125 2.2E-46 T 12-10-2018 AFE_1260 8eda4cf7742d0327106650292449fa47 161 Hamap MF_00984 Single-stranded DNA-binding protein. 4 111 36.274 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFE_1260 8eda4cf7742d0327106650292449fa47 161 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 117 3.9E-49 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFE_1260 8eda4cf7742d0327106650292449fa47 161 SUPERFAMILY SSF50249 3 142 2.33E-54 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1260 8eda4cf7742d0327106650292449fa47 161 Pfam PF00436 Single-strand binding protein family 4 106 7.3E-40 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AFE_2721 e635bb1a60c3c8f40ace90c6c7a564bc 510 SUPERFAMILY SSF55681 2 219 2.49E-34 T 12-10-2018 AFE_2721 e635bb1a60c3c8f40ace90c6c7a564bc 510 Pfam PF01976 Protein of unknown function DUF116 363 472 5.7E-9 T 12-10-2018 IPR002829 Protein of unknown function DUF116 AFE_2721 e635bb1a60c3c8f40ace90c6c7a564bc 510 Gene3D G3DSA:3.30.930.10 8 229 1.3E-26 T 12-10-2018 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 194 326 6.8E-44 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 SUPERFAMILY SSF52540 147 397 3.68E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 Gene3D G3DSA:1.20.58.760 408 604 5.0E-74 T 12-10-2018 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 Gene3D G3DSA:1.10.8.60 329 405 1.4E-30 T 12-10-2018 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 Gene3D G3DSA:2.40.50.920 27 102 1.7E-13 T 12-10-2018 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 Pfam PF06480 FtsH Extracellular 9 97 4.6E-12 T 12-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 ProSitePatterns PS00674 AAA-protein family signature. 297 315 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 Gene3D G3DSA:3.40.50.300 142 328 4.0E-70 T 12-10-2018 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 Pfam PF01434 Peptidase family M41 388 595 4.8E-81 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 SUPERFAMILY SSF140990 408 603 1.28E-71 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 104 596 5.9E-238 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 SMART SM00382 190 329 4.9E-24 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2636 b87ac913e25b7afa7c9f79b414001d31 641 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 619 37.662 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 Gene3D G3DSA:3.40.50.880 980 1283 3.7E-117 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1032 1280 3.9E-94 T 12-10-2018 AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 Gene3D G3DSA:1.10.8.750 155 215 2.7E-21 T 12-10-2018 AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 4 1281 0.0 T 12-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1283 19.803 T 12-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 SUPERFAMILY SSF55326 224 422 4.53E-53 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 SUPERFAMILY SSF109736 158 222 1.7E-19 T 12-10-2018 AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 Gene3D G3DSA:3.90.650.10 421 604 6.9E-51 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 Gene3D G3DSA:3.90.650.10 804 979 2.8E-29 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 SUPERFAMILY SSF52317 1029 1282 2.82E-89 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 SMART SM01211 1032 1282 1.1E-140 T 12-10-2018 AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 SUPERFAMILY SSF56042 431 654 3.74E-48 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 Gene3D G3DSA:3.30.1330.10 216 420 1.3E-40 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 SUPERFAMILY SSF56042 820 1009 2.99E-43 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 SUPERFAMILY SSF55326 618 815 7.33E-64 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 Gene3D G3DSA:3.30.1330.10 615 803 1.1E-23 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 Pfam PF02769 AIR synthase related protein, C-terminal domain 837 958 1.3E-12 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 Pfam PF02769 AIR synthase related protein, C-terminal domain 431 584 7.7E-27 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFE_2354 b03769bbc001b32ede49598ddd47ff7e 1283 SUPERFAMILY SSF82697 1 154 2.67E-38 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 SUPERFAMILY SSF82714 187 269 3.01E-15 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 Gene3D G3DSA:1.20.1640.10 15 505 8.7E-257 T 12-10-2018 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 1.7E-37 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 PRINTS PR00702 Acriflavin resistance protein family signature 469 492 1.7E-37 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 1.7E-37 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 1.7E-37 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 PRINTS PR00702 Acriflavin resistance protein family signature 444 467 1.7E-37 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 1.7E-37 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 1.7E-37 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 1.7E-37 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 Gene3D G3DSA:3.30.70.1430 560 663 8.7E-257 T 12-10-2018 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 Gene3D G3DSA:3.30.70.1320 136 328 8.7E-257 T 12-10-2018 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 Gene3D G3DSA:3.30.70.1440 664 863 8.7E-257 T 12-10-2018 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 Gene3D G3DSA:3.30.2090.10 715 803 8.7E-257 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 SUPERFAMILY SSF82693 43 128 1.64E-20 T 12-10-2018 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 Gene3D G3DSA:3.30.70.1430 43 811 8.7E-257 T 12-10-2018 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 5 1033 0.0 T 12-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 SUPERFAMILY SSF82866 294 497 3.92E-40 T 12-10-2018 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 SUPERFAMILY SSF82866 800 1033 3.14E-44 T 12-10-2018 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 Gene3D G3DSA:3.30.2090.10 183 274 8.7E-257 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 SUPERFAMILY SSF82714 715 798 1.57E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 Pfam PF00873 AcrB/AcrD/AcrF family 8 1028 3.6E-227 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 SUPERFAMILY SSF82693 139 326 2.01E-18 T 12-10-2018 AFE_2431 98d57ac4cfbc5b4888d872c7dd35e29c 1037 Gene3D G3DSA:1.20.1640.10 506 1027 8.7E-257 T 12-10-2018 AFE_1781 663083371ef9351d80a3631bed2c5c6f 70 SUPERFAMILY SSF89447 2 46 9.59E-8 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFE_1781 663083371ef9351d80a3631bed2c5c6f 70 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 3.3E-9 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_1781 663083371ef9351d80a3631bed2c5c6f 70 Gene3D G3DSA:2.10.260.10 1 43 3.9E-6 T 12-10-2018 AFE_1781 663083371ef9351d80a3631bed2c5c6f 70 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 48 2.1E-7 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_1781 663083371ef9351d80a3631bed2c5c6f 70 SMART SM00966 5 50 3.2E-8 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 12-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 Gene3D G3DSA:3.30.70.120 1 112 5.7E-48 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 PIRSF PIRSF039144 1 112 1.2E-56 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 SMART SM00938 4 105 4.1E-67 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.3E-43 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 SUPERFAMILY SSF54913 1 112 2.89E-46 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 PRINTS PR00340 P-II protein signature 83 103 1.4E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 PRINTS PR00340 P-II protein signature 2 17 1.4E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 PRINTS PR00340 P-II protein signature 23 41 1.4E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_0429 df4c67b9dd966a584c87ddd38a66fff3 112 PRINTS PR00340 P-II protein signature 52 75 1.4E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AFE_0668 19da785b968e17707921160718504c42 287 SUPERFAMILY SSF52540 52 191 3.53E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0668 19da785b968e17707921160718504c42 287 Pfam PF05673 Protein of unknown function (DUF815) 29 281 1.9E-96 T 12-10-2018 IPR008533 Domain of unknown function DUF815 AFE_0668 19da785b968e17707921160718504c42 287 SMART SM00382 78 200 2.8E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0668 19da785b968e17707921160718504c42 287 Gene3D G3DSA:3.40.50.300 49 192 1.4E-7 T 12-10-2018 AFE_2922 d76f061290c96711c81ed38f8a6df35f 408 SUPERFAMILY SSF51735 256 388 1.57E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2922 d76f061290c96711c81ed38f8a6df35f 408 SUPERFAMILY SSF81324 148 278 1.96E-21 T 12-10-2018 AFE_2922 d76f061290c96711c81ed38f8a6df35f 408 Gene3D G3DSA:3.40.50.720 255 400 1.4E-25 T 12-10-2018 AFE_2922 d76f061290c96711c81ed38f8a6df35f 408 Pfam PF02254 TrkA-N domain 259 372 8.9E-17 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFE_2922 d76f061290c96711c81ed38f8a6df35f 408 Pfam PF07885 Ion channel 161 235 8.3E-16 T 12-10-2018 IPR013099 Potassium channel domain AFE_2922 d76f061290c96711c81ed38f8a6df35f 408 Gene3D G3DSA:1.10.287.70 146 253 1.9E-17 T 12-10-2018 AFE_2697 6d0550c304cc97154ef6de00624ed48b 590 Pfam PF09977 Putative Tad-like Flp pilus-assembly 67 146 1.1E-9 T 12-10-2018 IPR018705 Domain of unknown function DUF2134, membrane AFE_2697 6d0550c304cc97154ef6de00624ed48b 590 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 18 63 1.2E-9 T 12-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal AFE_2006 f73e3b9ef630db45e9404b50d74e25d1 219 Pfam PF04299 Putative FMN-binding domain 2 168 5.8E-57 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type AFE_2006 f73e3b9ef630db45e9404b50d74e25d1 219 SUPERFAMILY SSF50475 11 194 2.94E-33 T 12-10-2018 AFE_2006 f73e3b9ef630db45e9404b50d74e25d1 219 PIRSF PIRSF010372 1 211 1.0E-65 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type AFE_2006 f73e3b9ef630db45e9404b50d74e25d1 219 Gene3D G3DSA:2.30.110.10 1 209 1.2E-67 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFE_3093 d02516d81bdd639f0e41ceed943a2bc4 420 Gene3D G3DSA:3.40.50.720 264 410 5.8E-26 T 12-10-2018 AFE_3093 d02516d81bdd639f0e41ceed943a2bc4 420 SUPERFAMILY SSF51735 266 396 2.36E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3093 d02516d81bdd639f0e41ceed943a2bc4 420 SUPERFAMILY SSF81324 143 286 5.63E-20 T 12-10-2018 AFE_3093 d02516d81bdd639f0e41ceed943a2bc4 420 Pfam PF02254 TrkA-N domain 270 382 1.5E-12 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFE_3093 d02516d81bdd639f0e41ceed943a2bc4 420 Pfam PF07885 Ion channel 171 243 1.1E-13 T 12-10-2018 IPR013099 Potassium channel domain AFE_3093 d02516d81bdd639f0e41ceed943a2bc4 420 Gene3D G3DSA:1.10.287.70 145 257 6.8E-16 T 12-10-2018 AFE_1634 2575bad71c3122e3d7e73a89ed0e5956 322 Gene3D G3DSA:3.40.50.300 126 320 6.3E-54 T 12-10-2018 AFE_1634 2575bad71c3122e3d7e73a89ed0e5956 322 SUPERFAMILY SSF52540 20 299 2.54E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1634 2575bad71c3122e3d7e73a89ed0e5956 322 Gene3D G3DSA:3.30.450.90 25 125 3.2E-11 T 12-10-2018 AFE_1634 2575bad71c3122e3d7e73a89ed0e5956 322 Pfam PF00437 Type II/IV secretion system protein 29 300 4.8E-74 T 12-10-2018 IPR001482 Type II/IV secretion system protein AFE_1634 2575bad71c3122e3d7e73a89ed0e5956 322 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 224 238 - T 12-10-2018 IPR001482 Type II/IV secretion system protein AFE_1634 2575bad71c3122e3d7e73a89ed0e5956 322 TIGRFAM TIGR02782 TrbB_P: P-type conjugative transfer ATPase TrbB 16 317 6.7E-142 T 12-10-2018 IPR014149 Conjugative transfer, TrbB GO:0000746|GO:0005737 AFE_0397 440c98bd88566fedc9ed2f37b2da2cc3 250 Pfam PF00753 Metallo-beta-lactamase superfamily 12 161 1.0E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_0397 440c98bd88566fedc9ed2f37b2da2cc3 250 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 162 249 1.1E-24 T 12-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AFE_0397 440c98bd88566fedc9ed2f37b2da2cc3 250 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 249 1.0E-99 T 12-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AFE_0397 440c98bd88566fedc9ed2f37b2da2cc3 250 PIRSF PIRSF005457 1 249 1.1E-88 T 12-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AFE_0397 440c98bd88566fedc9ed2f37b2da2cc3 250 SUPERFAMILY SSF56281 1 249 3.41E-69 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_0397 440c98bd88566fedc9ed2f37b2da2cc3 250 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 49 69 - T 12-10-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 AFE_0397 440c98bd88566fedc9ed2f37b2da2cc3 250 SMART SM00849 11 161 6.2E-36 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_0397 440c98bd88566fedc9ed2f37b2da2cc3 250 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 1 249 41.673 T 12-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 AFE_0397 440c98bd88566fedc9ed2f37b2da2cc3 250 Gene3D G3DSA:3.60.15.10 1 249 2.8E-84 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 2.5E-52 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.5E-52 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 2.5E-52 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 2.5E-52 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 2.5E-52 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 2.5E-52 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 2.5E-52 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 2.5E-52 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 2.5E-52 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 Gene3D G3DSA:3.50.50.60 149 274 8.7E-88 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 326 1.5E-51 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PIRSF PIRSF000350 2 461 1.7E-66 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 3.8E-24 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.8E-24 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 3.8E-24 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 3.8E-24 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 3.8E-24 T 12-10-2018 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 SUPERFAMILY SSF51905 6 336 4.16E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 457 6.1E-18 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 Gene3D G3DSA:3.30.390.30 347 462 3.6E-26 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 Gene3D G3DSA:3.50.50.60 7 325 8.7E-88 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1893 4f345c9278a216d3199adbc9e4ef08e9 462 SUPERFAMILY SSF55424 347 460 1.32E-24 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Pfam PF01103 Surface antigen 459 781 4.6E-63 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Pfam PF07244 Surface antigen variable number repeat 187 274 3.0E-15 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Pfam PF07244 Surface antigen variable number repeat 36 101 3.4E-5 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Pfam PF07244 Surface antigen variable number repeat 358 432 7.2E-11 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Pfam PF07244 Surface antigen variable number repeat 277 355 3.1E-14 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Pfam PF07244 Surface antigen variable number repeat 104 183 8.3E-8 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 2 781 23.492 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Gene3D G3DSA:3.10.20.310 31 102 1.3E-18 T 12-10-2018 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Gene3D G3DSA:2.40.160.50 436 781 2.1E-96 T 12-10-2018 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Gene3D G3DSA:3.10.20.310 280 354 7.0E-19 T 12-10-2018 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 PIRSF PIRSF006076 2 781 2.4E-237 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Gene3D G3DSA:3.10.20.310 103 184 4.5E-13 T 12-10-2018 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Gene3D G3DSA:3.10.20.310 359 435 1.2E-21 T 12-10-2018 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 Gene3D G3DSA:3.10.20.310 187 277 4.9E-20 T 12-10-2018 AFE_1452 0ffb197b8a99ceba1ff36a1e2e483f95 781 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 35 781 4.7E-259 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 AFE_1433 37d509e54a262276b5b1c9e9285a03b3 418 SMART SM00487 21 225 7.8E-59 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_1433 37d509e54a262276b5b1c9e9285a03b3 418 Pfam PF00271 Helicase conserved C-terminal domain 236 342 4.8E-28 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_1433 37d509e54a262276b5b1c9e9285a03b3 418 SUPERFAMILY SSF52540 78 361 2.06E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1433 37d509e54a262276b5b1c9e9285a03b3 418 SMART SM00490 261 342 4.6E-33 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_1433 37d509e54a262276b5b1c9e9285a03b3 418 Gene3D G3DSA:3.40.50.300 216 382 1.7E-52 T 12-10-2018 AFE_1433 37d509e54a262276b5b1c9e9285a03b3 418 Pfam PF00270 DEAD/DEAH box helicase 26 195 6.2E-49 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFE_1433 37d509e54a262276b5b1c9e9285a03b3 418 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 156 164 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AFE_1433 37d509e54a262276b5b1c9e9285a03b3 418 Gene3D G3DSA:3.40.50.300 1 214 1.2E-77 T 12-10-2018 AFE_3186 a3fac58e6181d76451debf7e3b297cb9 305 Pfam PF14338 Mrr N-terminal domain 6 90 2.6E-29 T 12-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain AFE_3186 a3fac58e6181d76451debf7e3b297cb9 305 Pfam PF04471 Restriction endonuclease 158 281 3.6E-34 T 12-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AFE_3186 a3fac58e6181d76451debf7e3b297cb9 305 Gene3D G3DSA:3.40.91.100 137 297 2.3E-9 T 12-10-2018 AFE_3186 a3fac58e6181d76451debf7e3b297cb9 305 SUPERFAMILY SSF52980 162 284 4.02E-15 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFE_1046 03b656e2016ff575550a886c3113a4d1 147 SUPERFAMILY SSF57783 6 53 2.04E-6 T 12-10-2018 AFE_1046 03b656e2016ff575550a886c3113a4d1 147 Gene3D G3DSA:3.90.580.10 2 81 1.4E-5 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 SUPERFAMILY SSF50800 74 165 1.74E-20 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 PRINTS PR01050 Pyruvate kinase family signature 293 311 3.5E-62 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 PRINTS PR01050 Pyruvate kinase family signature 243 267 3.5E-62 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 PRINTS PR01050 Pyruvate kinase family signature 268 292 3.5E-62 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 PRINTS PR01050 Pyruvate kinase family signature 312 328 3.5E-62 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 PRINTS PR01050 Pyruvate kinase family signature 186 200 3.5E-62 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 PRINTS PR01050 Pyruvate kinase family signature 216 242 3.5E-62 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 PRINTS PR01050 Pyruvate kinase family signature 63 79 3.5E-62 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 360 466 1.4E-14 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 SUPERFAMILY SSF51621 4 337 2.37E-92 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 7 465 1.9E-142 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 Gene3D G3DSA:2.40.33.10 74 168 1.1E-146 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 SUPERFAMILY SSF52935 322 468 9.62E-24 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 Gene3D G3DSA:3.40.1380.20 335 463 1.1E-146 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 Gene3D G3DSA:3.20.20.60 7 334 1.1E-146 T 12-10-2018 AFE_1801 72c8731082c5d01c0692d9f52c3c3b5f 474 Pfam PF00224 Pyruvate kinase, barrel domain 6 337 2.3E-111 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_1690 6c622d0ae0573aff92c35415e56cc620 110 Gene3D G3DSA:3.30.190.10 1 110 4.4E-43 T 12-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1690 6c622d0ae0573aff92c35415e56cc620 110 Pfam PF00101 Ribulose bisphosphate carboxylase, small chain 13 108 4.6E-38 T 12-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1690 6c622d0ae0573aff92c35415e56cc620 110 SMART SM00961 12 109 2.0E-49 T 12-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1690 6c622d0ae0573aff92c35415e56cc620 110 SUPERFAMILY SSF55239 5 108 2.36E-41 T 12-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 Gene3D G3DSA:3.30.565.10 281 432 2.1E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 391 4.7E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 413 4.7E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 377 4.7E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 SMART SM00387 326 434 8.8E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 SUPERFAMILY SSF55874 273 423 1.24E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 Gene3D G3DSA:1.10.287.130 169 280 2.2E-18 T 12-10-2018 AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 Pfam PF00512 His Kinase A (phospho-acceptor) domain 219 282 2.3E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 420 8.2E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 SUPERFAMILY SSF47384 202 281 1.22E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_2031 2f9ae9036e2538e0369f299dc1a3d5b0 435 SMART SM00388 218 283 2.5E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0191 83a72283c182f3d5d17c196fe27a88e3 80 Gene3D G3DSA:1.10.10.60 1 79 3.4E-20 T 12-10-2018 AFE_0191 83a72283c182f3d5d17c196fe27a88e3 80 PIRSF PIRSF002097 1 79 4.7E-21 T 12-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 AFE_0191 83a72283c182f3d5d17c196fe27a88e3 80 SUPERFAMILY SSF46689 5 79 2.37E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_0191 83a72283c182f3d5d17c196fe27a88e3 80 Pfam PF02954 Bacterial regulatory protein, Fis family 36 76 7.0E-13 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0191 83a72283c182f3d5d17c196fe27a88e3 80 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 59 79 1.3E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0191 83a72283c182f3d5d17c196fe27a88e3 80 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 42 59 1.3E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 369 41.199 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 SUPERFAMILY SSF49493 118 255 1.14E-18 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 PRINTS PR00625 DnaJ domain signature 7 25 7.1E-32 T 12-10-2018 IPR001623 DnaJ domain AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 PRINTS PR00625 DnaJ domain signature 62 81 7.1E-32 T 12-10-2018 IPR001623 DnaJ domain AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 PRINTS PR00625 DnaJ domain signature 25 40 7.1E-32 T 12-10-2018 IPR001623 DnaJ domain AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 PRINTS PR00625 DnaJ domain signature 42 62 7.1E-32 T 12-10-2018 IPR001623 DnaJ domain AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 SMART SM00271 4 62 4.9E-33 T 12-10-2018 IPR001623 DnaJ domain AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 Gene3D G3DSA:1.10.287.110 1 114 2.3E-36 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 12-10-2018 IPR018253 DnaJ domain, conserved site AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 Pfam PF00684 DnaJ central domain 146 206 1.2E-13 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 348 2.5E-134 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 Gene3D G3DSA:2.10.230.10 138 208 1.6E-23 T 12-10-2018 AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 SUPERFAMILY SSF57938 133 210 2.09E-21 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 Pfam PF00226 DnaJ domain 5 67 1.2E-28 T 12-10-2018 IPR001623 DnaJ domain AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 Gene3D G3DSA:2.60.260.20 254 360 1.7E-27 T 12-10-2018 AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 SUPERFAMILY SSF46565 1 109 2.62E-36 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 SUPERFAMILY SSF49493 258 343 2.35E-20 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFE_2664 a5d63ea26e2a6875b2999da328b4df74 375 Pfam PF01556 DnaJ C terminal domain 120 332 4.3E-42 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 Pfam PF00919 Uncharacterized protein family UPF0004 10 94 1.8E-20 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 Pfam PF01938 TRAM domain 378 444 5.3E-5 T 12-10-2018 IPR002792 TRAM domain AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 SUPERFAMILY SSF102114 124 374 6.93E-49 T 12-10-2018 AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 10 441 2.2E-158 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 Gene3D G3DSA:3.40.50.12160 10 129 7.4E-27 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 9 443 59.412 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 Pfam PF04055 Radical SAM superfamily 148 325 7.3E-27 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 Gene3D G3DSA:3.80.30.20 141 381 1.2E-69 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 Gene3D G3DSA:2.40.50.140 382 446 8.5E-15 T 12-10-2018 AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 SMART SM00729 142 367 7.4E-52 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 10 441 5.8E-100 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 AFE_0127 c3bcaf2b6503440cd01f594633944b0c 446 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 146 166 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 AFE_1394 e598cc4d870b682baf4d35a8da2afbb8 208 Gene3D G3DSA:1.10.10.10 135 205 1.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1394 e598cc4d870b682baf4d35a8da2afbb8 208 SUPERFAMILY SSF88659 136 199 3.55E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFE_1394 e598cc4d870b682baf4d35a8da2afbb8 208 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 197 5.4E-32 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFE_1394 e598cc4d870b682baf4d35a8da2afbb8 208 SUPERFAMILY SSF88946 17 121 3.61E-30 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFE_1394 e598cc4d870b682baf4d35a8da2afbb8 208 Pfam PF08281 Sigma-70, region 4 144 194 1.2E-18 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFE_1394 e598cc4d870b682baf4d35a8da2afbb8 208 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 60 91 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFE_1394 e598cc4d870b682baf4d35a8da2afbb8 208 Gene3D G3DSA:1.10.1740.10 13 134 4.4E-39 T 12-10-2018 AFE_1394 e598cc4d870b682baf4d35a8da2afbb8 208 Pfam PF04542 Sigma-70 region 2 38 105 2.3E-19 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFE_1394 e598cc4d870b682baf4d35a8da2afbb8 208 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 18 203 4.4E-105 T 12-10-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFE_1886 b938099305aa5b5561ffe06f69acbc4f 397 SUPERFAMILY SSF117892 142 255 4.58E-17 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily AFE_1886 b938099305aa5b5561ffe06f69acbc4f 397 TIGRFAM TIGR01933 hflK: HflK protein 82 344 4.6E-81 T 12-10-2018 IPR010201 HflK GO:0016021 AFE_1886 b938099305aa5b5561ffe06f69acbc4f 397 Gene3D G3DSA:3.30.479.30 138 241 2.1E-15 T 12-10-2018 AFE_1886 b938099305aa5b5561ffe06f69acbc4f 397 SMART SM00244 80 251 1.9E-24 T 12-10-2018 IPR001107 Band 7 domain AFE_1886 b938099305aa5b5561ffe06f69acbc4f 397 Pfam PF01145 SPFH domain / Band 7 family 84 266 1.4E-25 T 12-10-2018 IPR001107 Band 7 domain AFE_1886 b938099305aa5b5561ffe06f69acbc4f 397 Pfam PF12221 Bacterial membrane protein N terminal 1 48 4.9E-5 T 12-10-2018 IPR020980 Menbrane protein HflK, N-terminal AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 77 196 1.2E-9 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 15 226 1.5E-67 T 12-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 112 191 1.8E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 197 3.4E-32 T 12-10-2018 AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 Gene3D G3DSA:1.10.150.240 27 96 3.4E-58 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 4.8E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 4.8E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 186 199 4.8E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 12 23 4.8E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 SUPERFAMILY SSF56784 12 226 1.73E-58 T 12-10-2018 IPR036412 HAD-like superfamily AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 Gene3D G3DSA:3.40.50.1000 15 218 3.4E-58 T 12-10-2018 IPR023214 HAD superfamily AFE_3246 76f2aa070afbe3b4e0e4b1cde9a72210 227 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 12 227 34.511 T 12-10-2018 IPR037512 Phosphoglycolate phosphatase, prokaryotic GO:0005975|GO:0008967 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 SMART SM00917 422 552 5.1E-16 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 Gene3D G3DSA:3.30.160.270 377 551 2.7E-42 T 12-10-2018 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 SUPERFAMILY SSF110921 446 550 1.14E-20 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 38 54 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 241 254 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 Gene3D G3DSA:3.20.20.70 9 376 4.4E-149 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 Pfam PF08502 LeuA allosteric (dimerisation) domain 422 550 3.5E-18 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 Pfam PF00682 HMGL-like 32 308 2.0E-72 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 SUPERFAMILY SSF89000 388 437 1.41E-12 T 12-10-2018 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 SUPERFAMILY SSF51569 20 328 3.08E-99 T 12-10-2018 AFE_1989 7ea08e5da9922e5d29e563368ecce3b4 567 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 3 553 49.74 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_3242 9199ef61747d7ffa7a5c65851936bdda 263 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 36.188 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AFE_3242 9199ef61747d7ffa7a5c65851936bdda 263 SUPERFAMILY SSF51366 11 261 1.13E-85 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFE_3242 9199ef61747d7ffa7a5c65851936bdda 263 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 12-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 AFE_3242 9199ef61747d7ffa7a5c65851936bdda 263 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 259 3.2E-94 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AFE_3242 9199ef61747d7ffa7a5c65851936bdda 263 Gene3D G3DSA:3.20.20.70 1 263 1.3E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1137 896a3bedcdec0c74b6740ee3e3f8ae47 745 Gene3D G3DSA:1.10.10.160 133 237 1.3E-55 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily AFE_1137 896a3bedcdec0c74b6740ee3e3f8ae47 745 Gene3D G3DSA:3.40.50.300 4 321 1.3E-55 T 12-10-2018 AFE_1137 896a3bedcdec0c74b6740ee3e3f8ae47 745 SUPERFAMILY SSF52540 4 686 5.16E-105 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1137 896a3bedcdec0c74b6740ee3e3f8ae47 745 Gene3D G3DSA:1.10.486.10 431 601 8.8E-57 T 12-10-2018 AFE_1137 896a3bedcdec0c74b6740ee3e3f8ae47 745 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 318 3.2E-48 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFE_1137 896a3bedcdec0c74b6740ee3e3f8ae47 745 Gene3D G3DSA:3.40.50.300 329 682 8.8E-57 T 12-10-2018 AFE_1137 896a3bedcdec0c74b6740ee3e3f8ae47 745 Pfam PF13361 UvrD-like helicase C-terminal domain 326 680 9.3E-37 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFE_2733 a13a1e6809dad5143a3617be6d319e62 150 Pfam PF03703 Bacterial PH domain 71 123 1.9E-7 T 12-10-2018 IPR005182 Domain of unknown function DUF304 AFE_2147 36681a957d6524af0a2789963bb95006 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.9E-32 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_2147 36681a957d6524af0a2789963bb95006 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.9E-32 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_2147 36681a957d6524af0a2789963bb95006 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.9E-32 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_2147 36681a957d6524af0a2789963bb95006 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.9E-32 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_2147 36681a957d6524af0a2789963bb95006 363 Gene3D G3DSA:3.40.50.300 4 278 1.2E-149 T 12-10-2018 AFE_2147 36681a957d6524af0a2789963bb95006 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 9.9E-155 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFE_2147 36681a957d6524af0a2789963bb95006 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 43.658 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFE_2147 36681a957d6524af0a2789963bb95006 363 Pfam PF01926 50S ribosome-binding GTPase 5 122 1.0E-20 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 AFE_2147 36681a957d6524af0a2789963bb95006 363 Gene3D G3DSA:1.10.150.300 113 200 1.2E-149 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 AFE_2147 36681a957d6524af0a2789963bb95006 363 PIRSF PIRSF006641 1 363 1.4E-148 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFE_2147 36681a957d6524af0a2789963bb95006 363 SUPERFAMILY SSF81271 279 359 3.71E-36 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFE_2147 36681a957d6524af0a2789963bb95006 363 SUPERFAMILY SSF52540 5 301 9.26E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2147 36681a957d6524af0a2789963bb95006 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 1.7E-39 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 AFE_2147 36681a957d6524af0a2789963bb95006 363 Gene3D G3DSA:3.10.20.30 48 361 1.2E-149 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 435 4.8E-12 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.2E-24 T 12-10-2018 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 2.2E-24 T 12-10-2018 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 2.2E-24 T 12-10-2018 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.2E-24 T 12-10-2018 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 2.2E-24 T 12-10-2018 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 306 6.0E-53 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 Gene3D G3DSA:3.50.50.60 109 444 4.7E-100 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 392 407 5.3E-23 T 12-10-2018 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 5.3E-23 T 12-10-2018 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 5.3E-23 T 12-10-2018 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 5.3E-23 T 12-10-2018 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 5.3E-23 T 12-10-2018 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 SUPERFAMILY SSF51905 3 315 4.76E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 SUPERFAMILY SSF55424 329 448 9.11E-21 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_1803 ca42f2192e635229ca3c2923d74c0a38 465 Gene3D G3DSA:3.50.50.60 8 343 4.7E-100 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0696 6bf43b016ffb802cbf8ddb357855c743 194 SUPERFAMILY SSF51316 4 191 1.99E-49 T 12-10-2018 IPR011057 Mss4-like superfamily AFE_0696 6bf43b016ffb802cbf8ddb357855c743 194 Gene3D G3DSA:3.90.1590.10 1 193 6.9E-90 T 12-10-2018 AFE_0696 6bf43b016ffb802cbf8ddb357855c743 194 TIGRFAM TIGR02820 formald_GSH: S-(hydroxymethyl)glutathione synthase 7 188 5.6E-97 T 12-10-2018 IPR014185 Glutathione-dependent formaldehyde-activating enzyme GO:0008270|GO:0046294|GO:0051907 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AFE_0696 6bf43b016ffb802cbf8ddb357855c743 194 Hamap MF_00723 Glutathione-dependent formaldehyde-activating enzyme [gfa]. 1 194 125.197 T 12-10-2018 IPR014185 Glutathione-dependent formaldehyde-activating enzyme GO:0008270|GO:0046294|GO:0051907 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AFE_0696 6bf43b016ffb802cbf8ddb357855c743 194 PIRSF PIRSF033318 4 192 6.8E-99 T 12-10-2018 IPR014185 Glutathione-dependent formaldehyde-activating enzyme GO:0008270|GO:0046294|GO:0051907 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AFE_0696 6bf43b016ffb802cbf8ddb357855c743 194 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 49 115 4.6E-9 T 12-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AFE_2005 bde0e6f3aca76aee6e20382afef5c0be 228 Gene3D G3DSA:3.40.50.880 1 224 2.0E-71 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_2005 bde0e6f3aca76aee6e20382afef5c0be 228 Pfam PF01965 DJ-1/PfpI family 5 164 1.9E-28 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFE_2005 bde0e6f3aca76aee6e20382afef5c0be 228 SUPERFAMILY SSF52317 4 183 8.59E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_2929 8b0a8306a2a297b88b9a41d382519a00 419 PIRSF PIRSF003085 7 405 5.8E-127 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 AFE_2929 8b0a8306a2a297b88b9a41d382519a00 419 Gene3D G3DSA:3.40.50.150 118 392 6.6E-101 T 12-10-2018 AFE_2929 8b0a8306a2a297b88b9a41d382519a00 419 SUPERFAMILY SSF53335 120 387 1.13E-74 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2929 8b0a8306a2a297b88b9a41d382519a00 419 Pfam PF02353 Mycolic acid cyclopropane synthetase 109 383 1.0E-97 T 12-10-2018 AFE_0922 f68111cdf03056a979fb06dbbc67b590 487 Pfam PF07690 Major Facilitator Superfamily 27 418 4.5E-52 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_0922 f68111cdf03056a979fb06dbbc67b590 487 SUPERFAMILY SSF103473 14 471 2.35E-67 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_0922 f68111cdf03056a979fb06dbbc67b590 487 Gene3D G3DSA:1.20.1250.20 267 475 1.1E-19 T 12-10-2018 AFE_0922 f68111cdf03056a979fb06dbbc67b590 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 210 228 3.2E-8 T 12-10-2018 AFE_0922 f68111cdf03056a979fb06dbbc67b590 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 3.2E-8 T 12-10-2018 AFE_0922 f68111cdf03056a979fb06dbbc67b590 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 3.2E-8 T 12-10-2018 AFE_0922 f68111cdf03056a979fb06dbbc67b590 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 135 3.2E-8 T 12-10-2018 AFE_0922 f68111cdf03056a979fb06dbbc67b590 487 PRINTS PR01036 Tetracycline resistance protein TetB signature 367 387 3.2E-8 T 12-10-2018 AFE_0922 f68111cdf03056a979fb06dbbc67b590 487 Gene3D G3DSA:1.20.1720.10 22 256 7.9E-49 T 12-10-2018 AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 Gene3D G3DSA:3.20.20.80 227 626 4.4E-168 T 12-10-2018 AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 128 211 1.6E-23 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 SUPERFAMILY SSF81296 141 199 6.16E-11 T 12-10-2018 IPR014756 Immunoglobulin E-set AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 Gene3D G3DSA:2.60.40.10 12 225 2.2E-66 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 104 729 44.88 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 SUPERFAMILY SSF51011 628 728 1.22E-33 T 12-10-2018 AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 PIRSF PIRSF000463 14 731 3.4E-289 T 12-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 Gene3D G3DSA:2.60.40.1180 627 729 5.1E-36 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 SUPERFAMILY SSF81296 23 117 7.0E-12 T 12-10-2018 IPR014756 Immunoglobulin E-set AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 632 728 2.0E-21 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 113 726 5.6E-284 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 SUPERFAMILY SSF51445 183 620 5.76E-114 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 SMART SM00642 254 612 4.7E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFE_2836 1d5c52a3f1b008d91107dab20203e23a 732 Pfam PF00128 Alpha amylase, catalytic domain 280 347 8.5E-9 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFE_3008 7fe5b669e141eb23f2e3ab7ebc336438 524 Gene3D G3DSA:3.40.50.2000 319 492 1.4E-25 T 12-10-2018 AFE_3008 7fe5b669e141eb23f2e3ab7ebc336438 524 SUPERFAMILY SSF53756 165 517 9.94E-40 T 12-10-2018 AFE_3008 7fe5b669e141eb23f2e3ab7ebc336438 524 Pfam PF00534 Glycosyl transferases group 1 335 482 1.3E-16 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_3124 861327f18fd8d690073e9f624a6b7807 312 SUPERFAMILY SSF52402 16 220 5.35E-63 T 12-10-2018 AFE_3124 861327f18fd8d690073e9f624a6b7807 312 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 265 4.8E-46 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 AFE_3124 861327f18fd8d690073e9f624a6b7807 312 Gene3D G3DSA:3.40.50.620 17 222 2.6E-53 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_3124 861327f18fd8d690073e9f624a6b7807 312 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 19 312 4.0E-127 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFE_3124 861327f18fd8d690073e9f624a6b7807 312 PIRSF PIRSF002936 10 312 2.2E-139 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 SUPERFAMILY SSF50998 99 389 2.09E-61 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 Gene3D G3DSA:2.130.10.10 34 394 6.1E-82 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 12 390 1.4E-117 T 12-10-2018 IPR017687 Outer membrane protein assembly factor BamB AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 SMART SM00564 113 145 6.9E-4 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 SMART SM00564 328 360 120.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 SMART SM00564 250 281 110.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 SMART SM00564 198 230 1.3E-4 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 SMART SM00564 153 185 0.0013 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 SMART SM00564 287 319 0.012 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 8 392 27.72 T 12-10-2018 IPR017687 Outer membrane protein assembly factor BamB AFE_1936 b7c9445c23de1015154177e5f2f53d3a 395 Pfam PF13360 PQQ-like domain 114 318 1.1E-45 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFE_1654 4f4af024c8862dda1d47e9d13ecf49b5 282 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 15 269 29.759 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFE_1654 4f4af024c8862dda1d47e9d13ecf49b5 282 SUPERFAMILY SSF53927 22 268 2.59E-66 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFE_1654 4f4af024c8862dda1d47e9d13ecf49b5 282 Pfam PF02634 FdhD/NarQ family 34 268 8.0E-66 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFE_1654 4f4af024c8862dda1d47e9d13ecf49b5 282 PIRSF PIRSF015626 11 272 2.8E-66 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFE_1654 4f4af024c8862dda1d47e9d13ecf49b5 282 Gene3D G3DSA:3.40.140.10 128 273 4.8E-45 T 12-10-2018 AFE_1654 4f4af024c8862dda1d47e9d13ecf49b5 282 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 29 269 1.4E-51 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AFE_1654 4f4af024c8862dda1d47e9d13ecf49b5 282 Gene3D G3DSA:3.10.20.10 35 120 8.3E-11 T 12-10-2018 AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 Gene3D G3DSA:3.40.50.720 1 154 2.3E-50 T 12-10-2018 AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 Pfam PF13288 DXP reductoisomerase C-terminal domain 263 379 7.1E-41 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 PIRSF PIRSF006205 4 390 9.8E-151 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 SUPERFAMILY SSF51735 5 154 6.94E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 Gene3D G3DSA:1.10.1740.10 304 389 2.5E-29 T 12-10-2018 AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7 136 3.3E-43 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 SUPERFAMILY SSF55347 130 266 3.11E-62 T 12-10-2018 AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 SUPERFAMILY SSF69055 296 385 1.44E-30 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 7 384 46.054 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 150 231 1.6E-39 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFE_1450 7b520e9be864838756ae5affdfb93cf3 393 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6 387 1.9E-155 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFE_1295 780ead0ec217946b62a9c0729307e2b7 212 SUPERFAMILY SSF46689 140 208 1.52E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_1295 780ead0ec217946b62a9c0729307e2b7 212 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 188 208 1.4E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_1295 780ead0ec217946b62a9c0729307e2b7 212 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 171 188 1.4E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_1295 780ead0ec217946b62a9c0729307e2b7 212 Pfam PF02954 Bacterial regulatory protein, Fis family 166 205 4.3E-13 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_1295 780ead0ec217946b62a9c0729307e2b7 212 Gene3D G3DSA:1.10.10.60 143 211 1.0E-16 T 12-10-2018 AFE_1295 780ead0ec217946b62a9c0729307e2b7 212 Pfam PF00072 Response regulator receiver domain 32 113 1.3E-8 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_1295 780ead0ec217946b62a9c0729307e2b7 212 Gene3D G3DSA:3.40.50.2300 4 139 2.6E-14 T 12-10-2018 AFE_1295 780ead0ec217946b62a9c0729307e2b7 212 SUPERFAMILY SSF52172 21 144 4.55E-16 T 12-10-2018 IPR011006 CheY-like superfamily AFE_1387 5b866d3b6efb99a49a28611cc533b22b 378 Pfam PF10442 FIST C domain 220 358 1.1E-21 T 12-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFE_1387 5b866d3b6efb99a49a28611cc533b22b 378 SMART SM00897 35 218 8.7E-28 T 12-10-2018 IPR013702 FIST domain, N-terminal AFE_1387 5b866d3b6efb99a49a28611cc533b22b 378 SMART SM01204 219 360 2.2E-26 T 12-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFE_1387 5b866d3b6efb99a49a28611cc533b22b 378 Pfam PF08495 FIST N domain 37 217 9.5E-25 T 12-10-2018 IPR013702 FIST domain, N-terminal AFE_1387 5b866d3b6efb99a49a28611cc533b22b 378 PIRSF PIRSF018953 13 378 8.6E-49 T 12-10-2018 IPR016741 Uncharacterised conserved protein UCP018953 AFE_2075 fdae8566fcf2232938c0a7ba4e8e409e 358 Gene3D G3DSA:3.40.718.10 1 358 2.7E-157 T 12-10-2018 AFE_2075 fdae8566fcf2232938c0a7ba4e8e409e 358 SMART SM01329 3 350 6.5E-197 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFE_2075 fdae8566fcf2232938c0a7ba4e8e409e 358 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 3 348 1.3E-150 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 AFE_2075 fdae8566fcf2232938c0a7ba4e8e409e 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFE_2075 fdae8566fcf2232938c0a7ba4e8e409e 358 SUPERFAMILY SSF53659 2 355 1.23E-121 T 12-10-2018 AFE_2075 fdae8566fcf2232938c0a7ba4e8e409e 358 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 2 354 50.942 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 AFE_2075 fdae8566fcf2232938c0a7ba4e8e409e 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 350 4.0E-134 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFE_1882 f74010cd241641be5c13db3b2400e16d 192 PIRSF PIRSF006305 1 191 9.5E-43 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFE_1882 f74010cd241641be5c13db3b2400e16d 192 Hamap MF_00528 Septum formation protein Maf [maf]. 5 191 28.678 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFE_1882 f74010cd241641be5c13db3b2400e16d 192 Pfam PF02545 Maf-like protein 6 186 1.7E-42 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFE_1882 f74010cd241641be5c13db3b2400e16d 192 SUPERFAMILY SSF52972 4 186 1.24E-53 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFE_1882 f74010cd241641be5c13db3b2400e16d 192 Gene3D G3DSA:3.90.950.10 4 191 5.5E-57 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFE_1882 f74010cd241641be5c13db3b2400e16d 192 TIGRFAM TIGR00172 maf: septum formation protein Maf 5 185 1.1E-49 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFE_0730 7b42283cd41668bc45851b84909c1153 1475 SUPERFAMILY SSF51395 448 1185 1.24E-243 T 12-10-2018 AFE_0730 7b42283cd41668bc45851b84909c1153 1475 SUPERFAMILY SSF69336 1212 1466 9.16E-86 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFE_0730 7b42283cd41668bc45851b84909c1153 1475 SUPERFAMILY SSF56235 15 428 8.4E-130 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_0730 7b42283cd41668bc45851b84909c1153 1475 Pfam PF01493 GXGXG motif 1233 1419 5.5E-79 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 AFE_0730 7b42283cd41668bc45851b84909c1153 1475 Pfam PF04898 Glutamate synthase central domain 455 735 7.2E-102 T 12-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 AFE_0730 7b42283cd41668bc45851b84909c1153 1475 Gene3D G3DSA:3.60.20.10 15 541 0.0 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_0730 7b42283cd41668bc45851b84909c1153 1475 Pfam PF01645 Conserved region in glutamate synthase 791 1154 1.2E-151 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 AFE_0730 7b42283cd41668bc45851b84909c1153 1475 Gene3D G3DSA:2.160.20.60 1187 1468 5.9E-101 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFE_0730 7b42283cd41668bc45851b84909c1153 1475 Gene3D G3DSA:3.20.20.70 479 1167 0.0 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_0730 7b42283cd41668bc45851b84909c1153 1475 Pfam PF00310 Glutamine amidotransferases class-II 15 426 1.1E-149 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFE_0730 7b42283cd41668bc45851b84909c1153 1475 Gene3D G3DSA:3.20.20.70 431 790 0.0 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 473 483 1.7E-24 T 12-10-2018 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 526 545 1.7E-24 T 12-10-2018 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 158 172 1.7E-24 T 12-10-2018 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 561 1.7E-24 T 12-10-2018 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 316 330 1.7E-24 T 12-10-2018 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 318 324 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 SUPERFAMILY SSF81653 117 211 4.58E-21 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 13 689 38.361 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 16 686 5.2E-298 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 SUPERFAMILY SSF56784 312 574 5.63E-35 T 12-10-2018 IPR036412 HAD-like superfamily AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 78 337 4.0E-30 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 382 615 3.6E-44 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 Pfam PF00702 haloacid dehalogenase-like hydrolase 312 540 6.4E-33 T 12-10-2018 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 Pfam PF00122 E1-E2 ATPase 117 294 2.8E-33 T 12-10-2018 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 Gene3D G3DSA:3.40.1110.10 327 460 7.2E-43 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 SUPERFAMILY SSF81665 33 310 5.23E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFE_2233 173d5aed07b126503b68ebc0b60623bf 689 Gene3D G3DSA:2.70.150.20 109 215 3.3E-25 T 12-10-2018 AFE_0524 e6ad8fdfa59e43010728276859b62996 482 SMART SM00245 179 371 7.1E-69 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AFE_0524 e6ad8fdfa59e43010728276859b62996 482 Pfam PF03572 Peptidase family S41 205 370 2.9E-52 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AFE_0524 e6ad8fdfa59e43010728276859b62996 482 SUPERFAMILY SSF52096 40 375 2.65E-78 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFE_0524 e6ad8fdfa59e43010728276859b62996 482 SUPERFAMILY SSF50156 95 190 3.1E-20 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFE_0524 e6ad8fdfa59e43010728276859b62996 482 Gene3D G3DSA:2.30.42.10 106 193 6.0E-94 T 12-10-2018 AFE_0524 e6ad8fdfa59e43010728276859b62996 482 Gene3D G3DSA:3.90.226.10 194 368 6.0E-94 T 12-10-2018 AFE_0524 e6ad8fdfa59e43010728276859b62996 482 Gene3D G3DSA:3.30.750.44 56 346 6.0E-94 T 12-10-2018 AFE_0524 e6ad8fdfa59e43010728276859b62996 482 SMART SM00228 106 177 9.4E-16 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_0524 e6ad8fdfa59e43010728276859b62996 482 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 59 381 1.2E-97 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 AFE_0524 e6ad8fdfa59e43010728276859b62996 482 Pfam PF13180 PDZ domain 106 186 9.0E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_0296 fd34e7bbde6f91ba5a12ea274da970bf 163 Pfam PF03477 ATP cone domain 50 136 7.6E-16 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AFE_0296 fd34e7bbde6f91ba5a12ea274da970bf 163 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 154 83.536 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 AFE_0296 fd34e7bbde6f91ba5a12ea274da970bf 163 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 5.6E-62 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 AFE_1789 86b296d565ecfa6b733a6b699b4a38d3 403 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 3.7E-21 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFE_1789 86b296d565ecfa6b733a6b699b4a38d3 403 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 144 165 3.7E-21 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFE_1789 86b296d565ecfa6b733a6b699b4a38d3 403 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 66 85 3.7E-21 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFE_1789 86b296d565ecfa6b733a6b699b4a38d3 403 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 20 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_1789 86b296d565ecfa6b733a6b699b4a38d3 403 Gene3D G3DSA:3.40.50.620 3 215 3.5E-70 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_1789 86b296d565ecfa6b733a6b699b4a38d3 403 SUPERFAMILY SSF52374 4 396 9.07E-82 T 12-10-2018 AFE_1789 86b296d565ecfa6b733a6b699b4a38d3 403 Gene3D G3DSA:1.10.240.10 259 362 3.1E-37 T 12-10-2018 AFE_1789 86b296d565ecfa6b733a6b699b4a38d3 403 Pfam PF00579 tRNA synthetases class I (W and Y) 4 169 5.6E-47 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_1789 86b296d565ecfa6b733a6b699b4a38d3 403 Pfam PF00579 tRNA synthetases class I (W and Y) 227 347 1.1E-10 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_1789 86b296d565ecfa6b733a6b699b4a38d3 403 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 172 3.1E-54 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFE_1297 b64d8790bdfb53237150d25d2cad0a43 306 Gene3D G3DSA:3.40.50.300 48 220 6.3E-28 T 12-10-2018 AFE_1297 b64d8790bdfb53237150d25d2cad0a43 306 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 217 274 2.2E-6 T 12-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal AFE_1297 b64d8790bdfb53237150d25d2cad0a43 306 Pfam PF07728 AAA domain (dynein-related subfamily) 64 202 7.3E-24 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFE_1297 b64d8790bdfb53237150d25d2cad0a43 306 SUPERFAMILY SSF52540 52 267 5.55E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0401 5e56273bbce4078284c7bd6cb580de8c 136 SUPERFAMILY SSF103196 2 91 2.79E-15 T 12-10-2018 AFE_0401 5e56273bbce4078284c7bd6cb580de8c 136 Pfam PF03259 Roadblock/LC7 domain 11 90 4.3E-12 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFE_0401 5e56273bbce4078284c7bd6cb580de8c 136 Gene3D G3DSA:3.30.450.30 1 118 5.1E-16 T 12-10-2018 AFE_0401 5e56273bbce4078284c7bd6cb580de8c 136 SMART SM00960 1 91 2.1E-15 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFE_0179 d25210efa0c4502707f7aa85e9ff447a 337 Gene3D G3DSA:3.40.50.1400 2 321 3.6E-96 T 12-10-2018 AFE_0179 d25210efa0c4502707f7aa85e9ff447a 337 SUPERFAMILY SSF53800 2 325 1.42E-104 T 12-10-2018 AFE_0179 d25210efa0c4502707f7aa85e9ff447a 337 Hamap MF_00323 Ferrochelatase [hemH]. 1 321 34.591 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFE_0179 d25210efa0c4502707f7aa85e9ff447a 337 Gene3D G3DSA:3.40.50.1400 164 302 3.6E-96 T 12-10-2018 AFE_0179 d25210efa0c4502707f7aa85e9ff447a 337 Pfam PF00762 Ferrochelatase 2 317 9.9E-108 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFE_0179 d25210efa0c4502707f7aa85e9ff447a 337 ProSitePatterns PS00534 Ferrochelatase signature. 190 210 - T 12-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFE_0179 d25210efa0c4502707f7aa85e9ff447a 337 TIGRFAM TIGR00109 hemH: ferrochelatase 2 315 8.0E-87 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 Gene3D G3DSA:3.30.70.3280 397 536 9.2E-51 T 12-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 Gene3D G3DSA:3.40.50.300 80 386 5.9E-108 T 12-10-2018 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 66 81 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 161 3.0E-18 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 Pfam PF03144 Elongation factor Tu domain 2 321 385 2.0E-9 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 PRINTS PR00315 GTP-binding elongation factor signature 73 81 2.4E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 PRINTS PR00315 GTP-binding elongation factor signature 109 120 2.4E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 PRINTS PR00315 GTP-binding elongation factor signature 145 154 2.4E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 PRINTS PR00315 GTP-binding elongation factor signature 23 36 2.4E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 PRINTS PR00315 GTP-binding elongation factor signature 93 103 2.4E-10 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 12 534 52.024 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 Pfam PF16658 Class II release factor RF3, C-terminal domain 394 521 1.8E-46 T 12-10-2018 IPR032090 Peptide chain release factor 3, C-terminal AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 Gene3D G3DSA:3.40.50.300 118 282 5.9E-108 T 12-10-2018 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 Pfam PF00009 Elongation factor Tu GTP binding domain 20 285 5.6E-48 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 SUPERFAMILY SSF50447 268 399 6.03E-28 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 17 536 7.9E-246 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 SUPERFAMILY SSF54980 399 475 7.55E-18 T 12-10-2018 IPR035647 EF-G domain III/V-like AFE_2514 4b8bf770a2951ab97507f5ecc0f5bbeb 539 SUPERFAMILY SSF52540 18 285 1.66E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2682 3f4cc143e7a562760e2a8b19cc812c74 220 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 199 1.6E-5 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AFE_2682 3f4cc143e7a562760e2a8b19cc812c74 220 Pfam PF00633 Helix-hairpin-helix motif 100 127 8.3E-9 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 AFE_2682 3f4cc143e7a562760e2a8b19cc812c74 220 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 164 9.2E-18 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFE_2682 3f4cc143e7a562760e2a8b19cc812c74 220 PIRSF PIRSF001435 5 210 3.3E-44 T 12-10-2018 AFE_2682 3f4cc143e7a562760e2a8b19cc812c74 220 Hamap MF_00942 Endonuclease III [nth]. 1 209 35.328 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 AFE_2682 3f4cc143e7a562760e2a8b19cc812c74 220 SUPERFAMILY SSF48150 6 212 6.75E-69 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFE_2682 3f4cc143e7a562760e2a8b19cc812c74 220 SMART SM00478 38 185 7.4E-47 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFE_2682 3f4cc143e7a562760e2a8b19cc812c74 220 TIGRFAM TIGR01083 nth: endonuclease III 5 194 1.8E-74 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 AFE_2682 3f4cc143e7a562760e2a8b19cc812c74 220 Gene3D G3DSA:1.10.340.30 21 132 2.3E-71 T 12-10-2018 AFE_2682 3f4cc143e7a562760e2a8b19cc812c74 220 Gene3D G3DSA:1.10.1670.10 12 203 2.3E-71 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFE_0576 b1707d9a1f4c17567af681d29a02ab1d 462 Gene3D G3DSA:3.60.120.10 6 456 1.2E-155 T 12-10-2018 IPR005801 ADC synthase GO:0009058 AFE_0576 b1707d9a1f4c17567af681d29a02ab1d 462 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 107 450 6.9E-114 T 12-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 AFE_0576 b1707d9a1f4c17567af681d29a02ab1d 462 SUPERFAMILY SSF56322 5 455 1.14E-137 T 12-10-2018 IPR005801 ADC synthase GO:0009058 AFE_0576 b1707d9a1f4c17567af681d29a02ab1d 462 PRINTS PR00095 Anthranilate synthase component I signature 404 418 5.6E-16 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_0576 b1707d9a1f4c17567af681d29a02ab1d 462 PRINTS PR00095 Anthranilate synthase component I signature 309 322 5.6E-16 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_0576 b1707d9a1f4c17567af681d29a02ab1d 462 PRINTS PR00095 Anthranilate synthase component I signature 295 308 5.6E-16 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_0576 b1707d9a1f4c17567af681d29a02ab1d 462 PRINTS PR00095 Anthranilate synthase component I signature 389 403 5.6E-16 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_0576 b1707d9a1f4c17567af681d29a02ab1d 462 Pfam PF04715 Anthranilate synthase component I, N terminal region 18 152 2.4E-20 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_0576 b1707d9a1f4c17567af681d29a02ab1d 462 Pfam PF00425 chorismate binding enzyme 194 447 6.8E-101 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFE_2410 5a2a714ce4f7b92d97ffa84f129bf1ef 165 Gene3D G3DSA:3.40.630.30 2 164 4.3E-29 T 12-10-2018 AFE_2410 5a2a714ce4f7b92d97ffa84f129bf1ef 165 SUPERFAMILY SSF55729 4 159 3.66E-26 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_2410 5a2a714ce4f7b92d97ffa84f129bf1ef 165 Pfam PF13673 Acetyltransferase (GNAT) domain 37 136 1.4E-15 T 12-10-2018 IPR000182 GNAT domain AFE_3074 735f267690231ad6b5a7db9520dd0f85 128 ProSitePatterns PS00360 Ribosomal protein S9 signature. 67 85 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 AFE_3074 735f267690231ad6b5a7db9520dd0f85 128 Gene3D G3DSA:3.30.230.10 1 128 4.1E-51 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_3074 735f267690231ad6b5a7db9520dd0f85 128 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 128 30.527 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid AFE_3074 735f267690231ad6b5a7db9520dd0f85 128 SUPERFAMILY SSF54211 3 128 2.47E-47 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_3074 735f267690231ad6b5a7db9520dd0f85 128 Pfam PF00380 Ribosomal protein S9/S16 8 128 1.9E-45 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 Gene3D G3DSA:2.130.10.10 359 480 1.1E-11 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 Pfam PF13360 PQQ-like domain 62 268 3.2E-18 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 Pfam PF13360 PQQ-like domain 389 477 8.7E-7 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 Gene3D G3DSA:2.130.10.10 137 333 2.8E-23 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 Gene3D G3DSA:2.130.10.10 48 136 8.6E-10 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 SMART SM00564 416 447 190.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 SMART SM00564 170 202 17.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 SMART SM00564 212 248 58.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 SMART SM00564 113 162 750.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 SMART SM00564 67 105 0.11 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 SMART SM00564 375 408 22.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_1981 73bb275b74f9ad4b598a867ed9afca06 509 SUPERFAMILY SSF50998 31 455 9.76E-33 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFE_0945 efb89aff53598d001317d8deed70ecfe 530 Pfam PF00005 ABC transporter 336 467 5.8E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0945 efb89aff53598d001317d8deed70ecfe 530 Gene3D G3DSA:3.40.50.300 287 529 1.4E-53 T 12-10-2018 AFE_0945 efb89aff53598d001317d8deed70ecfe 530 SMART SM00382 26 238 6.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0945 efb89aff53598d001317d8deed70ecfe 530 SMART SM00382 344 512 1.8E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0945 efb89aff53598d001317d8deed70ecfe 530 SUPERFAMILY SSF52540 6 237 3.18E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0945 efb89aff53598d001317d8deed70ecfe 530 SUPERFAMILY SSF52540 296 523 2.07E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0945 efb89aff53598d001317d8deed70ecfe 530 Pfam PF12848 ABC transporter 224 305 1.6E-20 T 12-10-2018 IPR032781 ABC-transporter extension domain AFE_0945 efb89aff53598d001317d8deed70ecfe 530 Gene3D G3DSA:3.40.50.300 3 286 3.0E-59 T 12-10-2018 AFE_0945 efb89aff53598d001317d8deed70ecfe 530 Pfam PF00005 ABC transporter 18 184 1.1E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_3104 442e526f4f14648856d3e9efd924b339 576 Gene3D G3DSA:3.20.20.140 329 576 3.4E-69 T 12-10-2018 AFE_3104 442e526f4f14648856d3e9efd924b339 576 SMART SM00278 94 113 29.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_3104 442e526f4f14648856d3e9efd924b339 576 SMART SM00278 54 73 0.02 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_3104 442e526f4f14648856d3e9efd924b339 576 SMART SM00278 129 148 1.8 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_3104 442e526f4f14648856d3e9efd924b339 576 SUPERFAMILY SSF47802 2 83 2.88E-21 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily AFE_3104 442e526f4f14648856d3e9efd924b339 576 Gene3D G3DSA:3.30.210.10 263 327 3.0E-25 T 12-10-2018 IPR037160 DNA polymerase, thumb domain superfamily AFE_3104 442e526f4f14648856d3e9efd924b339 576 Pfam PF14520 Helix-hairpin-helix domain 95 150 3.2E-12 T 12-10-2018 AFE_3104 442e526f4f14648856d3e9efd924b339 576 Pfam PF14791 DNA polymerase beta thumb 256 316 7.5E-19 T 12-10-2018 IPR029398 DNA polymerase beta, thumb domain AFE_3104 442e526f4f14648856d3e9efd924b339 576 Pfam PF14716 Helix-hairpin-helix domain 5 75 1.2E-21 T 12-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain AFE_3104 442e526f4f14648856d3e9efd924b339 576 Gene3D G3DSA:1.10.150.110 2 88 1.9E-25 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily AFE_3104 442e526f4f14648856d3e9efd924b339 576 SUPERFAMILY SSF81301 158 316 5.06E-43 T 12-10-2018 AFE_3104 442e526f4f14648856d3e9efd924b339 576 SUPERFAMILY SSF89550 339 569 2.62E-51 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFE_3104 442e526f4f14648856d3e9efd924b339 576 Pfam PF02811 PHP domain 341 493 1.8E-7 T 12-10-2018 IPR004013 PHP domain GO:0003824 AFE_3104 442e526f4f14648856d3e9efd924b339 576 SUPERFAMILY SSF47781 93 155 1.04E-7 T 12-10-2018 IPR010994 RuvA domain 2-like AFE_3104 442e526f4f14648856d3e9efd924b339 576 SMART SM00481 340 419 9.8E-17 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFE_3104 442e526f4f14648856d3e9efd924b339 576 SMART SM00483 3 316 3.5E-28 T 12-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 AFE_3104 442e526f4f14648856d3e9efd924b339 576 Gene3D G3DSA:3.30.460.10 158 262 2.3E-27 T 12-10-2018 AFE_3104 442e526f4f14648856d3e9efd924b339 576 PIRSF PIRSF005047 3 574 9.3E-230 T 12-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3104 442e526f4f14648856d3e9efd924b339 576 Gene3D G3DSA:1.10.150.20 89 153 6.7E-22 T 12-10-2018 AFE_3104 442e526f4f14648856d3e9efd924b339 576 Pfam PF14792 DNA polymerase beta palm 170 215 1.1E-5 T 12-10-2018 IPR028207 DNA polymerase beta, palm domain AFE_3104 442e526f4f14648856d3e9efd924b339 576 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 61 78 2.1E-10 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3104 442e526f4f14648856d3e9efd924b339 576 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 186 205 2.1E-10 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_1441 182d4b340212c008c04fb46f03415fdf 503 Gene3D G3DSA:3.30.420.150 118 298 2.5E-77 T 12-10-2018 AFE_1441 182d4b340212c008c04fb46f03415fdf 503 Gene3D G3DSA:1.10.3210.10 313 502 2.3E-47 T 12-10-2018 AFE_1441 182d4b340212c008c04fb46f03415fdf 503 SUPERFAMILY SSF109604 316 498 8.48E-37 T 12-10-2018 AFE_1441 182d4b340212c008c04fb46f03415fdf 503 PIRSF PIRSF001267 4 501 9.2E-159 T 12-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 AFE_1441 182d4b340212c008c04fb46f03415fdf 503 Gene3D G3DSA:3.30.420.40 15 306 2.5E-77 T 12-10-2018 AFE_1441 182d4b340212c008c04fb46f03415fdf 503 SUPERFAMILY SSF53067 14 134 2.81E-31 T 12-10-2018 AFE_1441 182d4b340212c008c04fb46f03415fdf 503 Pfam PF02541 Ppx/GppA phosphatase family 36 310 3.4E-67 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 AFE_1441 182d4b340212c008c04fb46f03415fdf 503 SUPERFAMILY SSF53067 140 312 8.2E-40 T 12-10-2018 AFE_2517 7add12d2dc61d47f11e012cdde719ddc 641 Pfam PF00270 DEAD/DEAH box helicase 38 92 1.3E-5 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFE_2517 7add12d2dc61d47f11e012cdde719ddc 641 Pfam PF13307 Helicase C-terminal domain 466 623 1.0E-34 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFE_2517 7add12d2dc61d47f11e012cdde719ddc 641 Gene3D G3DSA:3.40.50.300 451 637 1.1E-35 T 12-10-2018 AFE_2517 7add12d2dc61d47f11e012cdde719ddc 641 SUPERFAMILY SSF52540 27 606 3.04E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2517 7add12d2dc61d47f11e012cdde719ddc 641 Gene3D G3DSA:3.40.50.300 28 268 3.9E-41 T 12-10-2018 AFE_2517 7add12d2dc61d47f11e012cdde719ddc 641 SMART SM00491 481 610 6.8E-39 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFE_2517 7add12d2dc61d47f11e012cdde719ddc 641 SMART SM00487 26 321 0.0018 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_2839 bd5e43d8f8da5af6f0b307debe5bd2da 568 SUPERFAMILY SSF88713 7 456 6.12E-84 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFE_2839 bd5e43d8f8da5af6f0b307debe5bd2da 568 Gene3D G3DSA:3.20.110.20 188 483 2.3E-17 T 12-10-2018 AFE_2839 bd5e43d8f8da5af6f0b307debe5bd2da 568 Pfam PF03065 Glycosyl hydrolase family 57 10 468 7.2E-71 T 12-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 AFE_2304 83a9133d50fe4ac2c42643b407532017 259 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 181 256 2.2E-9 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 AFE_2304 83a9133d50fe4ac2c42643b407532017 259 Gene3D G3DSA:3.30.1150.10 134 258 1.2E-17 T 12-10-2018 AFE_2304 83a9133d50fe4ac2c42643b407532017 259 SUPERFAMILY SSF74653 167 257 5.76E-9 T 12-10-2018 AFE_2304 83a9133d50fe4ac2c42643b407532017 259 PRINTS PR01217 Proline rich extensin signature 82 103 5.2E-13 T 12-10-2018 AFE_2304 83a9133d50fe4ac2c42643b407532017 259 PRINTS PR01217 Proline rich extensin signature 142 167 5.2E-13 T 12-10-2018 AFE_2304 83a9133d50fe4ac2c42643b407532017 259 PRINTS PR01217 Proline rich extensin signature 13 25 5.2E-13 T 12-10-2018 AFE_2304 83a9133d50fe4ac2c42643b407532017 259 PRINTS PR01217 Proline rich extensin signature 122 139 5.2E-13 T 12-10-2018 AFE_2304 83a9133d50fe4ac2c42643b407532017 259 PRINTS PR01217 Proline rich extensin signature 104 120 5.2E-13 T 12-10-2018 AFE_2304 83a9133d50fe4ac2c42643b407532017 259 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 182 256 1.9E-9 T 12-10-2018 IPR006260 TonB/TolA, C-terminal AFE_0382 63d7f7674a9dd3228b51d9a0f0e76765 347 Gene3D G3DSA:2.40.440.10 21 303 4.0E-88 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFE_0382 63d7f7674a9dd3228b51d9a0f0e76765 347 Pfam PF03734 L,D-transpeptidase catalytic domain 98 228 1.5E-18 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFE_0382 63d7f7674a9dd3228b51d9a0f0e76765 347 SUPERFAMILY SSF141523 96 229 7.46E-28 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFE_2667 52f360df2a50685dd8b8236f560eee80 340 PIRSF PIRSF005485 1 340 3.6E-100 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFE_2667 52f360df2a50685dd8b8236f560eee80 340 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 329 26.062 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFE_2667 52f360df2a50685dd8b8236f560eee80 340 SUPERFAMILY SSF46785 1 82 1.68E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2667 52f360df2a50685dd8b8236f560eee80 340 Pfam PF01628 HrcA protein C terminal domain 103 322 1.7E-53 T 12-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 AFE_2667 52f360df2a50685dd8b8236f560eee80 340 Gene3D G3DSA:3.30.390.60 127 227 3.0E-39 T 12-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily AFE_2667 52f360df2a50685dd8b8236f560eee80 340 Gene3D G3DSA:1.10.10.10 1 82 3.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2667 52f360df2a50685dd8b8236f560eee80 340 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 2 335 2.4E-93 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFE_2667 52f360df2a50685dd8b8236f560eee80 340 SUPERFAMILY SSF55781 70 338 7.85E-59 T 12-10-2018 AFE_2667 52f360df2a50685dd8b8236f560eee80 340 Gene3D G3DSA:3.30.450.40 103 332 3.0E-39 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 Pfam PF01476 LysM domain 438 480 3.0E-10 T 12-10-2018 IPR018392 LysM domain AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 Pfam PF01476 LysM domain 376 415 1.3E-8 T 12-10-2018 IPR018392 LysM domain AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 Pfam PF01476 LysM domain 501 543 7.3E-12 T 12-10-2018 IPR018392 LysM domain AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 Pfam PF01476 LysM domain 567 609 2.4E-13 T 12-10-2018 IPR018392 LysM domain AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 SUPERFAMILY SSF54106 565 610 1.44E-10 T 12-10-2018 AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 SMART SM00257 566 610 4.2E-13 T 12-10-2018 IPR018392 LysM domain AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 SMART SM00257 436 480 5.5E-9 T 12-10-2018 IPR018392 LysM domain AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 SMART SM00257 499 543 7.4E-11 T 12-10-2018 IPR018392 LysM domain AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 SMART SM00257 372 416 2.2E-8 T 12-10-2018 IPR018392 LysM domain AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 Gene3D G3DSA:3.10.350.10 374 422 4.7E-11 T 12-10-2018 IPR036779 LysM domain superfamily AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 SUPERFAMILY SSF54106 501 543 6.28E-9 T 12-10-2018 AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 SUPERFAMILY SSF54106 438 480 7.19E-7 T 12-10-2018 AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 Gene3D G3DSA:3.10.350.10 496 544 8.5E-14 T 12-10-2018 IPR036779 LysM domain superfamily AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 Pfam PF01464 Transglycosylase SLT domain 140 242 1.9E-23 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 SUPERFAMILY SSF54106 373 416 2.22E-7 T 12-10-2018 AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 Gene3D G3DSA:3.10.350.10 425 489 1.7E-11 T 12-10-2018 IPR036779 LysM domain superfamily AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 Gene3D G3DSA:3.10.350.10 550 612 6.6E-16 T 12-10-2018 IPR036779 LysM domain superfamily AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 151 179 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 Gene3D G3DSA:1.10.530.10 128 280 1.1E-30 T 12-10-2018 AFE_0421 fdbde26b0a393b186c1970f0a35efba1 612 SUPERFAMILY SSF53955 130 280 2.03E-36 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFE_0680 75124dab8cd2f49218caf40d0955d80f 352 Gene3D G3DSA:2.30.30.280 211 270 7.6E-15 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 AFE_0680 75124dab8cd2f49218caf40d0955d80f 352 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 4 348 6.3E-105 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 AFE_0680 75124dab8cd2f49218caf40d0955d80f 352 Gene3D G3DSA:2.40.30.10 272 352 4.5E-22 T 12-10-2018 AFE_0680 75124dab8cd2f49218caf40d0955d80f 352 Pfam PF03054 tRNA methyl transferase 5 348 1.3E-113 T 12-10-2018 AFE_0680 75124dab8cd2f49218caf40d0955d80f 352 Gene3D G3DSA:3.40.50.620 1 205 7.9E-79 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0680 75124dab8cd2f49218caf40d0955d80f 352 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 4 349 39.375 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 AFE_0680 75124dab8cd2f49218caf40d0955d80f 352 SUPERFAMILY SSF52402 3 240 2.65E-55 T 12-10-2018 AFE_1774 27156150dab0830c937b6ace3c8d451d 450 SUPERFAMILY SSF81891 180 440 1.26E-29 T 12-10-2018 AFE_1774 27156150dab0830c937b6ace3c8d451d 450 Gene3D G3DSA:3.30.460.10 20 177 2.2E-38 T 12-10-2018 AFE_1774 27156150dab0830c937b6ace3c8d451d 450 Pfam PF01743 Poly A polymerase head domain 54 182 5.5E-24 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFE_1774 27156150dab0830c937b6ace3c8d451d 450 Gene3D G3DSA:1.10.3090.10 178 441 7.6E-54 T 12-10-2018 AFE_1774 27156150dab0830c937b6ace3c8d451d 450 SUPERFAMILY SSF81301 32 178 6.87E-31 T 12-10-2018 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 225 238 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 287 302 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 Gene3D G3DSA:3.30.450.40 7 180 1.0E-44 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 TIGRFAM TIGR01817 nifA: Nif-specific regulatory protein 12 545 1.0E-213 T 12-10-2018 IPR010113 Nif-specific regulatory protein GO:0003700|GO:0006355|GO:0009399 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 SUPERFAMILY SSF52540 200 441 2.79E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 SMART SM00382 221 364 2.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 Gene3D G3DSA:1.10.8.60 372 448 4.8E-24 T 12-10-2018 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 SUPERFAMILY SSF55781 10 167 2.62E-20 T 12-10-2018 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 SUPERFAMILY SSF46689 497 540 7.17E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 Gene3D G3DSA:1.10.10.60 491 545 2.5E-9 T 12-10-2018 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 SMART SM00065 28 178 8.4E-21 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 Pfam PF02954 Bacterial regulatory protein, Fis family 498 538 3.8E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 Pfam PF01590 GAF domain 28 167 1.2E-12 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 Pfam PF00158 Sigma-54 interaction domain 201 367 3.4E-73 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 413 422 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 Gene3D G3DSA:3.40.50.300 185 371 1.1E-70 T 12-10-2018 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 504 521 1.7E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_1527 7a26a9b47a047b1cb3a9b1e9467c5d3c 545 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 521 541 1.7E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_2858 9a04ed790b01488340b5413c016be21d 436 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 1 433 3.8E-178 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFE_2858 9a04ed790b01488340b5413c016be21d 436 Pfam PF02040 Arsenical pump membrane protein 2 433 1.4E-142 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFE_2858 9a04ed790b01488340b5413c016be21d 436 PRINTS PR00758 Arsenical pump membrane protein signature 405 429 4.6E-84 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFE_2858 9a04ed790b01488340b5413c016be21d 436 PRINTS PR00758 Arsenical pump membrane protein signature 100 124 4.6E-84 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFE_2858 9a04ed790b01488340b5413c016be21d 436 PRINTS PR00758 Arsenical pump membrane protein signature 176 199 4.6E-84 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFE_2858 9a04ed790b01488340b5413c016be21d 436 PRINTS PR00758 Arsenical pump membrane protein signature 372 397 4.6E-84 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFE_2858 9a04ed790b01488340b5413c016be21d 436 PRINTS PR00758 Arsenical pump membrane protein signature 143 167 4.6E-84 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFE_2858 9a04ed790b01488340b5413c016be21d 436 PRINTS PR00758 Arsenical pump membrane protein signature 283 307 4.6E-84 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFE_3290 bbfa4a3ba0308d78f656f99227381382 370 Gene3D G3DSA:1.10.10.2140 317 368 1.1E-25 T 12-10-2018 AFE_3290 bbfa4a3ba0308d78f656f99227381382 370 Gene3D G3DSA:3.40.50.11750 20 262 8.4E-107 T 12-10-2018 AFE_3290 bbfa4a3ba0308d78f656f99227381382 370 PIRSF PIRSF005622 1 370 1.6E-155 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFE_3290 bbfa4a3ba0308d78f656f99227381382 370 Pfam PF01924 Hydrogenase formation hypA family 14 366 2.6E-154 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFE_3290 bbfa4a3ba0308d78f656f99227381382 370 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 3 368 1.8E-143 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFE_3290 bbfa4a3ba0308d78f656f99227381382 370 Gene3D G3DSA:3.40.50.11740 61 303 8.4E-107 T 12-10-2018 AFE_0341 778d172ee6e8bb7d5a3f95f05595c8d7 131 SUPERFAMILY SSF56047 3 130 8.76E-44 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0341 778d172ee6e8bb7d5a3f95f05595c8d7 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 30.918 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0341 778d172ee6e8bb7d5a3f95f05595c8d7 131 Gene3D G3DSA:3.30.1370.30 4 76 5.2E-27 T 12-10-2018 AFE_0341 778d172ee6e8bb7d5a3f95f05595c8d7 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0341 778d172ee6e8bb7d5a3f95f05595c8d7 131 Pfam PF00410 Ribosomal protein S8 5 130 1.4E-47 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0341 778d172ee6e8bb7d5a3f95f05595c8d7 131 Gene3D G3DSA:3.30.1490.10 77 130 5.8E-24 T 12-10-2018 AFE_3280 fae9be5077d7f98ca2d77ed13864545e 183 Gene3D G3DSA:3.90.280.10 1 176 3.5E-25 T 12-10-2018 IPR036610 PEBP-like superfamily AFE_3280 fae9be5077d7f98ca2d77ed13864545e 183 Pfam PF01161 Phosphatidylethanolamine-binding protein 20 133 4.8E-14 T 12-10-2018 IPR008914 Phosphatidylethanolamine-binding protein AFE_3280 fae9be5077d7f98ca2d77ed13864545e 183 SUPERFAMILY SSF49777 3 130 1.44E-20 T 12-10-2018 IPR036610 PEBP-like superfamily AFE_0942 852def32890135ad387ca58ffc28ed7f 1113 Pfam PF00271 Helicase conserved C-terminal domain 942 1051 9.1E-17 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0942 852def32890135ad387ca58ffc28ed7f 1113 Gene3D G3DSA:3.40.50.300 863 1065 2.7E-79 T 12-10-2018 AFE_0942 852def32890135ad387ca58ffc28ed7f 1113 Gene3D G3DSA:1.20.120.850 878 1094 2.7E-79 T 12-10-2018 AFE_0942 852def32890135ad387ca58ffc28ed7f 1113 SUPERFAMILY SSF52540 613 856 6.08E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0942 852def32890135ad387ca58ffc28ed7f 1113 Pfam PF00176 SNF2 family N-terminal domain 659 928 2.9E-57 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 AFE_0942 852def32890135ad387ca58ffc28ed7f 1113 SMART SM00490 971 1051 3.0E-20 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0942 852def32890135ad387ca58ffc28ed7f 1113 Gene3D G3DSA:3.40.50.10810 646 857 1.7E-61 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily AFE_0942 852def32890135ad387ca58ffc28ed7f 1113 SUPERFAMILY SSF52540 858 1105 1.67E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0942 852def32890135ad387ca58ffc28ed7f 1113 SMART SM00487 641 828 2.0E-29 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_1516 e5301fffb83904fbc3c0c136cda03227 453 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 19 425 2.5E-112 T 12-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 AFE_1516 e5301fffb83904fbc3c0c136cda03227 453 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 37 44 - T 12-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 AFE_1516 e5301fffb83904fbc3c0c136cda03227 453 SUPERFAMILY SSF53807 6 436 2.0E-131 T 12-10-2018 AFE_1516 e5301fffb83904fbc3c0c136cda03227 453 Gene3D G3DSA:3.40.50.1980 160 415 9.8E-120 T 12-10-2018 AFE_1516 e5301fffb83904fbc3c0c136cda03227 453 Gene3D G3DSA:3.40.50.1980 19 159 9.8E-120 T 12-10-2018 AFE_1516 e5301fffb83904fbc3c0c136cda03227 453 Gene3D G3DSA:1.20.89.10 266 431 9.8E-120 T 12-10-2018 AFE_1516 e5301fffb83904fbc3c0c136cda03227 453 TIGRFAM TIGR01285 nifN: nitrogenase molybdenum-iron cofactor biosynthesis protein NifN 3 427 1.3E-175 T 12-10-2018 IPR005975 Nitrogenase molybdenum-iron cofactor biosynthesis protein GO:0009399|GO:0065003 AFE_1516 e5301fffb83904fbc3c0c136cda03227 453 Gene3D G3DSA:3.40.50.1980 8 408 9.8E-120 T 12-10-2018 AFE_1354 3a95f350c1a0fc4af975cf6b164b3573 382 Gene3D G3DSA:3.40.50.2000 14 375 4.0E-64 T 12-10-2018 AFE_1354 3a95f350c1a0fc4af975cf6b164b3573 382 SUPERFAMILY SSF53756 14 380 1.4E-71 T 12-10-2018 AFE_1354 3a95f350c1a0fc4af975cf6b164b3573 382 Gene3D G3DSA:3.40.50.2000 177 358 4.0E-64 T 12-10-2018 AFE_1354 3a95f350c1a0fc4af975cf6b164b3573 382 Pfam PF13439 Glycosyltransferase Family 4 19 179 7.3E-22 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_1354 3a95f350c1a0fc4af975cf6b164b3573 382 Pfam PF00534 Glycosyl transferases group 1 192 345 1.7E-29 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1467 7c3abdf017ed9fabc9dcf5f9ffa41e9e 158 SUPERFAMILY SSF46785 18 148 1.5E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1467 7c3abdf017ed9fabc9dcf5f9ffa41e9e 158 Pfam PF01475 Ferric uptake regulator family 26 120 9.1E-11 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFE_1467 7c3abdf017ed9fabc9dcf5f9ffa41e9e 158 Gene3D G3DSA:1.10.10.10 13 91 9.9E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0017 6e7b3768bf54316e41324628881cd850 365 Pfam PF02481 DNA recombination-mediator protein A 73 274 5.6E-72 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 AFE_0017 6e7b3768bf54316e41324628881cd850 365 Gene3D G3DSA:3.40.50.450 1 287 8.6E-102 T 12-10-2018 AFE_0017 6e7b3768bf54316e41324628881cd850 365 Gene3D G3DSA:1.10.10.10 289 360 1.5E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0017 6e7b3768bf54316e41324628881cd850 365 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 69 283 6.0E-72 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 AFE_0017 6e7b3768bf54316e41324628881cd850 365 SUPERFAMILY SSF102405 80 283 2.52E-43 T 12-10-2018 AFE_2574 5b306dfad6f95c9c838eb57a8332bec5 490 SUPERFAMILY SSF48452 80 447 7.05E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2139 7363364e39acd5e9a4b6856f8b733b55 266 SUPERFAMILY SSF56300 4 259 1.65E-78 T 12-10-2018 AFE_2139 7363364e39acd5e9a4b6856f8b733b55 266 Pfam PF13277 YmdB-like protein 5 257 2.4E-98 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like AFE_2139 7363364e39acd5e9a4b6856f8b733b55 266 PIRSF PIRSF004789 1 265 3.3E-91 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like AFE_2139 7363364e39acd5e9a4b6856f8b733b55 266 Gene3D G3DSA:3.60.21.10 1 265 1.2E-99 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFE_2361 5f9836d5e05bedf4626f85671a9c05d4 442 SMART SM00646 222 378 8.4E-44 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFE_2361 5f9836d5e05bedf4626f85671a9c05d4 442 SUPERFAMILY SSF53187 160 381 3.11E-48 T 12-10-2018 AFE_2361 5f9836d5e05bedf4626f85671a9c05d4 442 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 162 377 7.0E-44 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFE_2361 5f9836d5e05bedf4626f85671a9c05d4 442 Gene3D G3DSA:3.10.350.10 386 441 2.7E-5 T 12-10-2018 IPR036779 LysM domain superfamily AFE_2361 5f9836d5e05bedf4626f85671a9c05d4 442 Gene3D G3DSA:3.40.630.40 148 385 2.1E-67 T 12-10-2018 AFE_2215 1fa43f680186653d0633aa89edb78205 264 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 72 220 4.0E-25 T 12-10-2018 IPR006342 Methyltransferase FkbM AFE_2215 1fa43f680186653d0633aa89edb78205 264 Gene3D G3DSA:3.40.50.150 57 246 6.7E-31 T 12-10-2018 AFE_2215 1fa43f680186653d0633aa89edb78205 264 SUPERFAMILY SSF53335 21 241 8.64E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2215 1fa43f680186653d0633aa89edb78205 264 Pfam PF05050 Methyltransferase FkbM domain 73 239 1.8E-18 T 12-10-2018 IPR006342 Methyltransferase FkbM AFE_0204 a76b89cb82a6bfe31a4ebe07a63380d7 295 Gene3D G3DSA:3.90.78.10 207 295 3.4E-33 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0204 a76b89cb82a6bfe31a4ebe07a63380d7 295 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 15 290 1.1E-61 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0204 a76b89cb82a6bfe31a4ebe07a63380d7 295 Gene3D G3DSA:3.30.43.10 3 77 7.1E-21 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 AFE_0204 a76b89cb82a6bfe31a4ebe07a63380d7 295 SUPERFAMILY SSF56176 15 198 1.7E-36 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFE_0204 a76b89cb82a6bfe31a4ebe07a63380d7 295 SUPERFAMILY SSF56194 188 291 1.44E-34 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0204 a76b89cb82a6bfe31a4ebe07a63380d7 295 Gene3D G3DSA:3.30.465.10 84 206 5.2E-29 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFE_0204 a76b89cb82a6bfe31a4ebe07a63380d7 295 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 192 289 4.0E-30 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0204 a76b89cb82a6bfe31a4ebe07a63380d7 295 Pfam PF01565 FAD binding domain 29 157 7.1E-18 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFE_0204 a76b89cb82a6bfe31a4ebe07a63380d7 295 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 295 85.294 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_3166 ca4167312f7ed74386282aa574334fa8 153 SUPERFAMILY SSF55729 12 144 7.48E-31 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_3166 ca4167312f7ed74386282aa574334fa8 153 Gene3D G3DSA:3.40.630.30 11 149 1.1E-25 T 12-10-2018 AFE_3166 ca4167312f7ed74386282aa574334fa8 153 Pfam PF00583 Acetyltransferase (GNAT) family 49 138 3.6E-15 T 12-10-2018 IPR000182 GNAT domain AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 3 417 40.116 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 SMART SM01210 324 417 2.4E-49 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 SMART SM01209 105 290 2.0E-113 T 12-10-2018 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 4 416 5.8E-151 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 Gene3D G3DSA:3.40.50.20 4 97 1.2E-36 T 12-10-2018 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 Gene3D G3DSA:3.30.1490.20 123 185 4.2E-19 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 325 415 1.1E-29 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 284 291 - T 12-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 105 290 1.6E-65 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 SUPERFAMILY SSF51246 323 417 2.51E-30 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 SUPERFAMILY SSF56059 106 320 9.9E-54 T 12-10-2018 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 Gene3D G3DSA:3.90.600.10 324 420 3.1E-33 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 Gene3D G3DSA:3.30.470.20 186 323 1.8E-48 T 12-10-2018 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 4 104 3.0E-33 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFE_2261 dc57a2a873359e20baf3e09b74b69495 420 SUPERFAMILY SSF52440 3 105 2.01E-34 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 Gene3D G3DSA:3.30.70.1430 603 713 9.1E-237 T 12-10-2018 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 SUPERFAMILY SSF82714 761 848 3.14E-10 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 SUPERFAMILY SSF82714 193 273 2.88E-15 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 Pfam PF00873 AcrB/AcrD/AcrF family 20 1080 3.4E-155 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 Gene3D G3DSA:3.30.2090.10 762 852 9.1E-237 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.2E-27 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 PRINTS PR00702 Acriflavin resistance protein family signature 48 66 1.2E-27 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 PRINTS PR00702 Acriflavin resistance protein family signature 406 430 1.2E-27 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 PRINTS PR00702 Acriflavin resistance protein family signature 352 375 1.2E-27 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 PRINTS PR00702 Acriflavin resistance protein family signature 486 509 1.2E-27 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 PRINTS PR00702 Acriflavin resistance protein family signature 20 44 1.2E-27 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 Gene3D G3DSA:3.30.70.1320 144 346 9.1E-237 T 12-10-2018 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 SUPERFAMILY SSF82693 144 344 2.07E-14 T 12-10-2018 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 Gene3D G3DSA:1.20.1640.10 24 528 9.1E-237 T 12-10-2018 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 SUPERFAMILY SSF82693 604 714 2.67E-10 T 12-10-2018 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 Gene3D G3DSA:3.30.70.1430 50 860 9.1E-237 T 12-10-2018 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 SUPERFAMILY SSF82693 50 144 4.97E-16 T 12-10-2018 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 SUPERFAMILY SSF82866 311 513 4.84E-39 T 12-10-2018 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 Gene3D G3DSA:3.30.2090.10 188 284 9.1E-237 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 SUPERFAMILY SSF82866 850 1087 5.23E-45 T 12-10-2018 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 Gene3D G3DSA:3.30.70.1440 714 929 9.1E-237 T 12-10-2018 AFE_2366 9f1e43340ff9fff9d05c60d7741214ba 1092 Gene3D G3DSA:1.20.1640.10 529 1079 9.1E-237 T 12-10-2018 AFE_2827 1ed217961c0af6a3ae19df08e744e88e 184 Pfam PF03734 L,D-transpeptidase catalytic domain 15 170 2.6E-11 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFE_2827 1ed217961c0af6a3ae19df08e744e88e 184 Gene3D G3DSA:2.40.440.10 2 177 1.9E-20 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFE_2827 1ed217961c0af6a3ae19df08e744e88e 184 SUPERFAMILY SSF141523 13 170 4.05E-19 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFE_3303 255f1c50bbecb33a593a65cfbf7dd764 430 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 4 426 105.048 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFE_3303 255f1c50bbecb33a593a65cfbf7dd764 430 Gene3D G3DSA:3.90.1150.10 8 418 1.2E-175 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_3303 255f1c50bbecb33a593a65cfbf7dd764 430 SUPERFAMILY SSF53383 3 424 4.5E-132 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_3303 255f1c50bbecb33a593a65cfbf7dd764 430 Pfam PF00202 Aminotransferase class-III 34 395 4.6E-75 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFE_3303 255f1c50bbecb33a593a65cfbf7dd764 430 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 425 7.8E-183 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFE_3303 255f1c50bbecb33a593a65cfbf7dd764 430 Gene3D G3DSA:3.40.640.10 70 318 1.2E-175 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_3303 255f1c50bbecb33a593a65cfbf7dd764 430 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 271 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFE_2430 d3e63bbece51fe50b0c146e8ca7625ac 228 Gene3D G3DSA:3.60.160.10 14 225 6.0E-19 T 12-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily AFE_2430 d3e63bbece51fe50b0c146e8ca7625ac 228 SUPERFAMILY SSF51219 17 220 3.4E-23 T 12-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily AFE_2430 d3e63bbece51fe50b0c146e8ca7625ac 228 Pfam PF01987 Mitochondrial biogenesis AIM24 19 220 3.7E-19 T 12-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 AFE_0761 a88c68597864dc9e553d75df673ec3ba 316 SUPERFAMILY SSF53850 105 312 1.57E-31 T 12-10-2018 AFE_0761 a88c68597864dc9e553d75df673ec3ba 316 Gene3D G3DSA:1.10.10.10 14 103 9.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0761 a88c68597864dc9e553d75df673ec3ba 316 Gene3D G3DSA:3.40.190.290 105 314 7.9E-34 T 12-10-2018 AFE_0761 a88c68597864dc9e553d75df673ec3ba 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 77 8.2E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0761 a88c68597864dc9e553d75df673ec3ba 316 SUPERFAMILY SSF46785 14 126 3.05E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0761 a88c68597864dc9e553d75df673ec3ba 316 Pfam PF03466 LysR substrate binding domain 103 309 1.8E-32 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_0761 a88c68597864dc9e553d75df673ec3ba 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 54 7.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0761 a88c68597864dc9e553d75df673ec3ba 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 65 7.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0761 a88c68597864dc9e553d75df673ec3ba 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 44 7.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_3022 2932ede071529ca9d19c324aa662457f 310 Gene3D G3DSA:3.40.50.300 133 310 2.3E-58 T 12-10-2018 AFE_3022 2932ede071529ca9d19c324aa662457f 310 Pfam PF02603 HPr Serine kinase N terminus 39 129 1.2E-8 T 12-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 AFE_3022 2932ede071529ca9d19c324aa662457f 310 Gene3D G3DSA:3.40.1390.20 38 132 1.5E-8 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AFE_3022 2932ede071529ca9d19c324aa662457f 310 SUPERFAMILY SSF53795 136 299 1.83E-30 T 12-10-2018 AFE_3022 2932ede071529ca9d19c324aa662457f 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 40 305 6.5E-84 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 AFE_3022 2932ede071529ca9d19c324aa662457f 310 Pfam PF07475 HPr Serine kinase C-terminal domain 132 302 5.0E-57 T 12-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 AFE_3022 2932ede071529ca9d19c324aa662457f 310 SUPERFAMILY SSF75138 10 133 4.71E-11 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AFE_2604 3c9a00a1a3839e22d93b72f566a75b3c 307 SUPERFAMILY SSF52540 13 235 2.07E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2604 3c9a00a1a3839e22d93b72f566a75b3c 307 Pfam PF00005 ABC transporter 33 172 1.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2604 3c9a00a1a3839e22d93b72f566a75b3c 307 SMART SM00382 42 221 3.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2604 3c9a00a1a3839e22d93b72f566a75b3c 307 Gene3D G3DSA:3.40.50.300 9 243 1.7E-53 T 12-10-2018 AFE_2604 3c9a00a1a3839e22d93b72f566a75b3c 307 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2223 15c22f47c14d361ece4d11a42785ffaf 829 SUPERFAMILY SSF56601 231 782 1.07E-104 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_2223 15c22f47c14d361ece4d11a42785ffaf 829 SUPERFAMILY SSF53955 59 274 7.03E-64 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFE_2223 15c22f47c14d361ece4d11a42785ffaf 829 Pfam PF00912 Transglycosylase 71 249 1.9E-51 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_2223 15c22f47c14d361ece4d11a42785ffaf 829 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 82 764 1.2E-158 T 12-10-2018 AFE_2223 15c22f47c14d361ece4d11a42785ffaf 829 Gene3D G3DSA:2.40.50.140 343 439 7.3E-9 T 12-10-2018 AFE_2223 15c22f47c14d361ece4d11a42785ffaf 829 Pfam PF00905 Penicillin binding protein transpeptidase domain 470 735 5.4E-23 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFE_2223 15c22f47c14d361ece4d11a42785ffaf 829 Gene3D G3DSA:1.10.3810.10 65 265 9.8E-63 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_2223 15c22f47c14d361ece4d11a42785ffaf 829 Pfam PF17092 Penicillin-binding protein OB-like domain 342 468 3.4E-18 T 12-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_2223 15c22f47c14d361ece4d11a42785ffaf 829 Gene3D G3DSA:3.40.710.10 269 342 2.8E-8 T 12-10-2018 AFE_2223 15c22f47c14d361ece4d11a42785ffaf 829 Gene3D G3DSA:3.40.710.10 448 793 2.4E-98 T 12-10-2018 AFE_0211 9193b6a80d4228672d0a0aeb547bddeb 483 Gene3D G3DSA:3.90.190.20 339 483 9.6E-56 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_0211 9193b6a80d4228672d0a0aeb547bddeb 483 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 5 481 29.438 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 AFE_0211 9193b6a80d4228672d0a0aeb547bddeb 483 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 481 1.7E-124 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 AFE_0211 9193b6a80d4228672d0a0aeb547bddeb 483 Gene3D G3DSA:3.40.1190.10 107 330 1.9E-62 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_0211 9193b6a80d4228672d0a0aeb547bddeb 483 SUPERFAMILY SSF53623 108 319 7.33E-61 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_0211 9193b6a80d4228672d0a0aeb547bddeb 483 SUPERFAMILY SSF53244 329 476 5.49E-43 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_0211 9193b6a80d4228672d0a0aeb547bddeb 483 Gene3D G3DSA:3.40.1390.10 3 100 1.8E-13 T 12-10-2018 AFE_0211 9193b6a80d4228672d0a0aeb547bddeb 483 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 413 7.2E-19 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFE_0211 9193b6a80d4228672d0a0aeb547bddeb 483 SUPERFAMILY SSF63418 7 100 8.5E-14 T 12-10-2018 IPR035911 MurE/MurF, N-terminal AFE_0211 9193b6a80d4228672d0a0aeb547bddeb 483 Pfam PF08245 Mur ligase middle domain 112 309 8.3E-44 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 Gene3D G3DSA:3.50.50.60 7 313 1.2E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 SUPERFAMILY SSF51905 1 334 3.17E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 Gene3D G3DSA:3.30.390.30 321 400 6.8E-19 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 SUPERFAMILY SSF55424 320 388 1.01E-16 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 5.0E-19 T 12-10-2018 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.0E-19 T 12-10-2018 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 5.0E-19 T 12-10-2018 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 5.0E-19 T 12-10-2018 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 304 3.0E-42 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 SMART SM01353 307 388 2.1E-5 T 12-10-2018 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 Pfam PF14721 Apoptosis-inducing factor, mitochondrion-associated, C-term 354 387 2.5E-8 T 12-10-2018 IPR029324 Mitochondrial apoptosis-inducing factor, C-terminal domain GO:0046983 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 7.4E-5 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 7.4E-5 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 7.4E-5 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFE_0859 d564ea834320b60f95bb6fc9c86d9871 403 Gene3D G3DSA:3.50.50.60 44 239 1.2E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1451 ed4fab17a5f46d2b7c84fa400193c4c4 452 SUPERFAMILY SSF50156 213 276 4.99E-13 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFE_1451 ed4fab17a5f46d2b7c84fa400193c4c4 452 Pfam PF13180 PDZ domain 223 276 2.7E-8 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_1451 ed4fab17a5f46d2b7c84fa400193c4c4 452 Gene3D G3DSA:2.30.42.10 222 307 8.5E-17 T 12-10-2018 AFE_1451 ed4fab17a5f46d2b7c84fa400193c4c4 452 SMART SM00228 121 188 0.11 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_1451 ed4fab17a5f46d2b7c84fa400193c4c4 452 SMART SM00228 207 279 0.054 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_1451 ed4fab17a5f46d2b7c84fa400193c4c4 452 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 1 450 2.7E-104 T 12-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 AFE_1451 ed4fab17a5f46d2b7c84fa400193c4c4 452 Gene3D G3DSA:2.30.42.10 128 221 3.5E-13 T 12-10-2018 AFE_1451 ed4fab17a5f46d2b7c84fa400193c4c4 452 Pfam PF02163 Peptidase family M50 9 437 1.9E-76 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFE_1451 ed4fab17a5f46d2b7c84fa400193c4c4 452 SUPERFAMILY SSF50156 90 188 4.21E-14 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFE_0948 b2d24b7c4db54916246db2ffcc79ae48 627 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 139 594 100.442 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFE_0948 b2d24b7c4db54916246db2ffcc79ae48 627 Gene3D G3DSA:3.20.20.540 213 525 1.5E-152 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFE_0948 b2d24b7c4db54916246db2ffcc79ae48 627 Pfam PF01964 Radical SAM ThiC family 141 589 7.8E-200 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFE_0948 b2d24b7c4db54916246db2ffcc79ae48 627 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 139 592 1.0E-216 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFE_0948 b2d24b7c4db54916246db2ffcc79ae48 627 Pfam PF13667 ThiC-associated domain 21 93 2.1E-22 T 12-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFE_0034 18a3c4d13eaa28d12803b6271fdeb7e8 116 Pfam PF00825 Ribonuclease P 11 115 4.4E-26 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFE_0034 18a3c4d13eaa28d12803b6271fdeb7e8 116 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 60 74 - T 12-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 AFE_0034 18a3c4d13eaa28d12803b6271fdeb7e8 116 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 17 114 7.0E-13 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFE_0034 18a3c4d13eaa28d12803b6271fdeb7e8 116 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 11 115 16.282 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFE_0034 18a3c4d13eaa28d12803b6271fdeb7e8 116 SUPERFAMILY SSF54211 10 115 1.54E-25 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0034 18a3c4d13eaa28d12803b6271fdeb7e8 116 Gene3D G3DSA:3.30.230.10 10 116 2.5E-28 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_0034 18a3c4d13eaa28d12803b6271fdeb7e8 116 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 14 115 5.1E-27 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFE_0214 2339a30074cda8ff65c3bf17332b2fd4 321 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 9 315 1.1E-95 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFE_0214 2339a30074cda8ff65c3bf17332b2fd4 321 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 11 316 36.092 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFE_0214 2339a30074cda8ff65c3bf17332b2fd4 321 Pfam PF01795 MraW methylase family 9 315 2.5E-98 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFE_0214 2339a30074cda8ff65c3bf17332b2fd4 321 SUPERFAMILY SSF81799 123 222 2.75E-34 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 AFE_0214 2339a30074cda8ff65c3bf17332b2fd4 321 Gene3D G3DSA:1.10.150.170 121 223 2.8E-94 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 AFE_0214 2339a30074cda8ff65c3bf17332b2fd4 321 SUPERFAMILY SSF53335 11 315 1.32E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0214 2339a30074cda8ff65c3bf17332b2fd4 321 PIRSF PIRSF004486 5 317 8.0E-93 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFE_0214 2339a30074cda8ff65c3bf17332b2fd4 321 Gene3D G3DSA:3.40.50.150 11 314 2.8E-94 T 12-10-2018 AFE_0263 0baf7eddfb9a1eadd7beed81e385e0fb 222 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 68 82 - T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFE_0263 0baf7eddfb9a1eadd7beed81e385e0fb 222 SUPERFAMILY SSF51419 1 215 5.09E-60 T 12-10-2018 IPR029066 PLP-binding barrel AFE_0263 0baf7eddfb9a1eadd7beed81e385e0fb 222 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 5 216 27.233 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFE_0263 0baf7eddfb9a1eadd7beed81e385e0fb 222 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 21 217 3.3E-54 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFE_0263 0baf7eddfb9a1eadd7beed81e385e0fb 222 PIRSF PIRSF004848 1 221 5.8E-56 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFE_0263 0baf7eddfb9a1eadd7beed81e385e0fb 222 Gene3D G3DSA:3.20.20.10 1 220 1.9E-63 T 12-10-2018 IPR029066 PLP-binding barrel AFE_0263 0baf7eddfb9a1eadd7beed81e385e0fb 222 Pfam PF01168 Alanine racemase, N-terminal domain 22 217 3.9E-22 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 SUPERFAMILY SSF55785 191 295 3.22E-13 T 12-10-2018 IPR035965 PAS domain superfamily AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 Pfam PF13426 PAS domain 188 286 3.3E-6 T 12-10-2018 IPR000014 PAS domain AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 Pfam PF00563 EAL domain 474 705 5.8E-52 T 12-10-2018 IPR001633 EAL domain AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 Gene3D G3DSA:3.30.70.270 291 462 6.2E-53 T 12-10-2018 AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 295 460 8.7E-44 T 12-10-2018 IPR000160 GGDEF domain AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 Gene3D G3DSA:3.20.20.450 472 725 1.4E-65 T 12-10-2018 IPR035919 EAL domain superfamily AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 Gene3D G3DSA:3.30.450.20 174 290 1.4E-15 T 12-10-2018 AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 Gene3D G3DSA:3.30.450.40 1 170 1.9E-16 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 191 292 3.3E-8 T 12-10-2018 IPR000014 PAS domain AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 SUPERFAMILY SSF55781 3 160 1.37E-17 T 12-10-2018 AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 Pfam PF13185 GAF domain 14 156 5.2E-15 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 SMART SM00065 15 167 0.0051 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 SUPERFAMILY SSF55073 303 461 1.41E-44 T 12-10-2018 IPR029787 Nucleotide cyclase AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 SMART SM00052 471 710 7.2E-53 T 12-10-2018 IPR001633 EAL domain AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 SMART SM00267 287 461 2.7E-58 T 12-10-2018 IPR000160 GGDEF domain AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 Pfam PF00990 Diguanylate cyclase, GGDEF domain 300 456 4.9E-45 T 12-10-2018 IPR000160 GGDEF domain AFE_3057 53c747257d9e10bd9af176df5dfc1a58 841 SUPERFAMILY SSF141868 474 721 4.18E-61 T 12-10-2018 IPR035919 EAL domain superfamily AFE_2821 d815a5387bec62a170e5d2f49242e8b0 193 Pfam PF09991 Predicted membrane protein (DUF2232) 41 179 3.6E-18 T 12-10-2018 IPR018710 Protein of unknown function DUF2232 AFE_0195 1f788cfced44760b5de85eb578aca118 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 324 2.1E-81 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFE_0195 1f788cfced44760b5de85eb578aca118 448 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 2.8E-220 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 AFE_0195 1f788cfced44760b5de85eb578aca118 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 7.7E-46 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFE_0195 1f788cfced44760b5de85eb578aca118 448 Pfam PF02785 Biotin carboxylase C-terminal domain 338 443 6.6E-39 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFE_0195 1f788cfced44760b5de85eb578aca118 448 SUPERFAMILY SSF52440 1 113 1.51E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFE_0195 1f788cfced44760b5de85eb578aca118 448 SUPERFAMILY SSF51246 333 446 3.56E-42 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFE_0195 1f788cfced44760b5de85eb578aca118 448 SUPERFAMILY SSF56059 83 347 2.83E-70 T 12-10-2018 AFE_0195 1f788cfced44760b5de85eb578aca118 448 Gene3D G3DSA:3.30.470.130 1 447 5.0E-191 T 12-10-2018 AFE_0195 1f788cfced44760b5de85eb578aca118 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFE_0195 1f788cfced44760b5de85eb578aca118 448 SMART SM00878 338 443 3.8E-62 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFE_0195 1f788cfced44760b5de85eb578aca118 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFE_2193 36baa726449336939e6e0e716f18e567 279 Gene3D G3DSA:3.60.21.10 2 269 1.0E-60 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFE_2193 36baa726449336939e6e0e716f18e567 279 PIRSF PIRSF000903 2 271 2.9E-81 T 12-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 AFE_2193 36baa726449336939e6e0e716f18e567 279 Pfam PF00149 Calcineurin-like phosphoesterase 6 187 2.2E-10 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFE_2193 36baa726449336939e6e0e716f18e567 279 SUPERFAMILY SSF56300 4 262 2.89E-42 T 12-10-2018 AFE_0047 1e2b4e11c6dd2f1785c745a687f58370 165 Pfam PF08534 Redoxin 33 156 2.0E-20 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AFE_0047 1e2b4e11c6dd2f1785c745a687f58370 165 Gene3D G3DSA:3.40.30.10 22 165 1.3E-34 T 12-10-2018 AFE_0047 1e2b4e11c6dd2f1785c745a687f58370 165 SUPERFAMILY SSF52833 32 164 2.9E-33 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1455 9be385d561ff6628caff8fad51e19c5d 148 Gene3D G3DSA:3.10.129.10 1 145 1.7E-58 T 12-10-2018 AFE_1455 9be385d561ff6628caff8fad51e19c5d 148 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 4 142 5.1E-57 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFE_1455 9be385d561ff6628caff8fad51e19c5d 148 Pfam PF07977 FabA-like domain 13 137 8.1E-37 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFE_1455 9be385d561ff6628caff8fad51e19c5d 148 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 4 145 34.101 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFE_1455 9be385d561ff6628caff8fad51e19c5d 148 SUPERFAMILY SSF54637 3 141 2.55E-48 T 12-10-2018 IPR029069 HotDog domain superfamily AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 SMART SM01011 6 140 1.6E-55 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 Gene3D G3DSA:3.40.350.10 8 175 1.1E-52 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 Gene3D G3DSA:3.90.230.10 177 443 1.7E-96 T 12-10-2018 AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 PRINTS PR00599 Methionine aminopeptidase-1 signature 257 273 6.4E-6 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 PRINTS PR00599 Methionine aminopeptidase-1 signature 235 248 6.4E-6 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 PRINTS PR00599 Methionine aminopeptidase-1 signature 376 388 6.4E-6 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 SUPERFAMILY SSF53092 10 178 1.96E-50 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 Pfam PF00557 Metallopeptidase family M24 185 417 1.3E-63 T 12-10-2018 IPR000994 Peptidase M24 AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 SUPERFAMILY SSF55920 179 439 8.11E-82 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 Pfam PF05195 Aminopeptidase P, N-terminal domain 11 127 8.8E-37 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 AFE_2815 0a3d203b688e7c11480e6e3ccdd7d51d 446 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 352 364 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site AFE_2442 8400126e93424d2dc8c9ac28c80178a3 102 Pfam PF14712 Snapin/Pallidin 4 89 2.2E-12 T 12-10-2018 IPR028119 Snapin/Pallidin/Snn1 Reactome: R-HSA-432722 AFE_2442 8400126e93424d2dc8c9ac28c80178a3 102 SUPERFAMILY SSF161266 37 98 9.15E-5 T 12-10-2018 AFE_0737 542c494622bd1d7afa63e3e17cb2f5b1 217 Pfam PF04350 Pilus assembly protein, PilO 51 202 8.3E-49 T 12-10-2018 IPR007445 Pilus assembly protein, PilO AFE_0737 542c494622bd1d7afa63e3e17cb2f5b1 217 PIRSF PIRSF016482 1 217 2.4E-55 T 12-10-2018 IPR007445 Pilus assembly protein, PilO AFE_0737 542c494622bd1d7afa63e3e17cb2f5b1 217 Gene3D G3DSA:3.30.70.60 94 210 1.5E-35 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 AFE_0737 542c494622bd1d7afa63e3e17cb2f5b1 217 SUPERFAMILY SSF58100 22 96 7.06E-5 T 12-10-2018 AFE_2228 048e1c038d91210b2e832eb6a57c35b7 247 Pfam PF00072 Response regulator receiver domain 11 128 9.2E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_2228 048e1c038d91210b2e832eb6a57c35b7 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 166 240 2.6E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2228 048e1c038d91210b2e832eb6a57c35b7 247 Gene3D G3DSA:1.10.10.10 141 244 1.9E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2228 048e1c038d91210b2e832eb6a57c35b7 247 SUPERFAMILY SSF52172 8 189 5.62E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFE_2228 048e1c038d91210b2e832eb6a57c35b7 247 SMART SM00862 164 240 1.1E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2228 048e1c038d91210b2e832eb6a57c35b7 247 Gene3D G3DSA:3.40.50.2300 2 140 3.3E-29 T 12-10-2018 AFE_2228 048e1c038d91210b2e832eb6a57c35b7 247 SMART SM00448 9 128 5.9E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0621 a5e503dcb89f4581b9d4858f6c7c59c5 222 SMART SM00855 4 156 5.7E-24 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFE_0621 a5e503dcb89f4581b9d4858f6c7c59c5 222 SUPERFAMILY SSF53254 3 190 3.19E-60 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFE_0621 a5e503dcb89f4581b9d4858f6c7c59c5 222 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 AFE_0621 a5e503dcb89f4581b9d4858f6c7c59c5 222 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 188 3.8E-63 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFE_0621 a5e503dcb89f4581b9d4858f6c7c59c5 222 PIRSF PIRSF000709 2 184 7.8E-15 T 12-10-2018 AFE_0621 a5e503dcb89f4581b9d4858f6c7c59c5 222 Gene3D G3DSA:3.40.50.1240 3 193 2.2E-65 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFE_3079 467abc2da56f52fbb46c26ae164e4c96 199 SUPERFAMILY SSF55469 1 195 8.11E-52 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFE_3079 467abc2da56f52fbb46c26ae164e4c96 199 Pfam PF00881 Nitroreductase family 8 177 3.6E-30 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFE_3079 467abc2da56f52fbb46c26ae164e4c96 199 Gene3D G3DSA:3.40.109.10 1 195 6.1E-47 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFE_2040 7c25cbe7cd9a9a3a8e9a5a313f8dc3bd 787 Gene3D G3DSA:2.40.170.20 203 787 8.4E-47 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily AFE_2040 7c25cbe7cd9a9a3a8e9a5a313f8dc3bd 787 Pfam PF00593 TonB dependent receptor 309 784 3.4E-30 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_2040 7c25cbe7cd9a9a3a8e9a5a313f8dc3bd 787 SUPERFAMILY SSF56935 65 787 2.42E-60 T 12-10-2018 AFE_2040 7c25cbe7cd9a9a3a8e9a5a313f8dc3bd 787 Gene3D G3DSA:2.170.130.10 59 197 1.2E-5 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_3037 3686d6e53146dfbf6bb434a58ed52e12 110 SUPERFAMILY SSF82657 16 105 7.46E-28 T 12-10-2018 IPR036065 BolA-like superfamily AFE_3037 3686d6e53146dfbf6bb434a58ed52e12 110 Gene3D G3DSA:3.30.300.90 27 101 6.5E-30 T 12-10-2018 AFE_3037 3686d6e53146dfbf6bb434a58ed52e12 110 Pfam PF01722 BolA-like protein 50 100 1.5E-18 T 12-10-2018 IPR002634 BolA protein AFE_1933 98a8871ca32f18df8d34032ea57e325e 366 SUPERFAMILY SSF51604 21 138 9.89E-10 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFE_1933 98a8871ca32f18df8d34032ea57e325e 366 Gene3D G3DSA:3.30.413.10 262 362 6.0E-29 T 12-10-2018 AFE_1933 98a8871ca32f18df8d34032ea57e325e 366 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 352 1.3E-132 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFE_1933 98a8871ca32f18df8d34032ea57e325e 366 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 357 35.703 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFE_1933 98a8871ca32f18df8d34032ea57e325e 366 Gene3D G3DSA:3.20.20.20 1 261 6.1E-110 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFE_1933 98a8871ca32f18df8d34032ea57e325e 366 PIRSF PIRSF004640 1 363 2.0E-153 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFE_1933 98a8871ca32f18df8d34032ea57e325e 366 SUPERFAMILY SSF56014 266 354 1.94E-12 T 12-10-2018 AFE_1933 98a8871ca32f18df8d34032ea57e325e 366 Pfam PF04551 GcpE protein 12 353 2.7E-138 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFE_1564 d5e72a3dff70948f466082a9e68a2013 74 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 10 63 6.7E-19 T 12-10-2018 IPR031856 Putative bacterial antitoxin YdaS AFE_1564 d5e72a3dff70948f466082a9e68a2013 74 SUPERFAMILY SSF47413 11 62 6.14E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_1564 d5e72a3dff70948f466082a9e68a2013 74 Gene3D G3DSA:1.10.260.40 6 72 1.3E-18 T 12-10-2018 AFE_2411 0802fdaf1e01e42545ade84ccb18d90d 158 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 1.0E-76 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2411 0802fdaf1e01e42545ade84ccb18d90d 158 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2411 0802fdaf1e01e42545ade84ccb18d90d 158 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.191 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2411 0802fdaf1e01e42545ade84ccb18d90d 158 Gene3D G3DSA:3.40.50.12280 2 158 4.4E-78 T 12-10-2018 AFE_2411 0802fdaf1e01e42545ade84ccb18d90d 158 SUPERFAMILY SSF56770 9 153 4.84E-66 T 12-10-2018 AFE_2411 0802fdaf1e01e42545ade84ccb18d90d 158 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 1.8E-21 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_3264 ae0793c9019e7e8186fa3dae853238be 377 Gene3D G3DSA:1.10.287.470 94 167 8.3E-63 T 12-10-2018 AFE_3264 ae0793c9019e7e8186fa3dae853238be 377 SUPERFAMILY SSF111369 48 283 8.63E-56 T 12-10-2018 AFE_3264 ae0793c9019e7e8186fa3dae853238be 377 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 59 279 2.4E-13 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_3264 ae0793c9019e7e8186fa3dae853238be 377 Gene3D G3DSA:2.40.50.100 59 202 8.3E-63 T 12-10-2018 AFE_3264 ae0793c9019e7e8186fa3dae853238be 377 Gene3D G3DSA:2.40.420.20 271 359 1.6E-9 T 12-10-2018 AFE_3264 ae0793c9019e7e8186fa3dae853238be 377 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 35 358 6.8E-68 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_3264 ae0793c9019e7e8186fa3dae853238be 377 Gene3D G3DSA:2.40.30.170 53 270 8.3E-63 T 12-10-2018 AFE_2186 15b0bd1510ddb8f328706f5d741950b0 272 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 257 1.1E-73 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFE_2186 15b0bd1510ddb8f328706f5d741950b0 272 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 259 18.483 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFE_2186 15b0bd1510ddb8f328706f5d741950b0 272 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 11 254 1.6E-71 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFE_2060 5b49a065c2daabb26b9bdea01c291c74 345 Pfam PF02547 Queuosine biosynthesis protein 4 338 2.1E-127 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFE_2060 5b49a065c2daabb26b9bdea01c291c74 345 SUPERFAMILY SSF111337 1 338 7.59E-128 T 12-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFE_2060 5b49a065c2daabb26b9bdea01c291c74 345 Gene3D G3DSA:2.40.10.240 64 161 3.8E-112 T 12-10-2018 AFE_2060 5b49a065c2daabb26b9bdea01c291c74 345 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 339 45.025 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFE_2060 5b49a065c2daabb26b9bdea01c291c74 345 Gene3D G3DSA:3.40.1780.10 14 338 3.8E-112 T 12-10-2018 AFE_2060 5b49a065c2daabb26b9bdea01c291c74 345 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 338 5.9E-123 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFE_0353 509274423e13179bb42d7fe3804e9e7e 208 SUPERFAMILY SSF55174 4 208 1.11E-66 T 12-10-2018 AFE_0353 509274423e13179bb42d7fe3804e9e7e 208 Gene3D G3DSA:1.10.1050.10 6 208 1.4E-83 T 12-10-2018 AFE_0353 509274423e13179bb42d7fe3804e9e7e 208 Pfam PF01479 S4 domain 99 145 2.7E-20 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0353 509274423e13179bb42d7fe3804e9e7e 208 Gene3D G3DSA:3.10.290.10 97 193 1.4E-83 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFE_0353 509274423e13179bb42d7fe3804e9e7e 208 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 208 35.17 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFE_0353 509274423e13179bb42d7fe3804e9e7e 208 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 97 1.7E-32 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFE_0353 509274423e13179bb42d7fe3804e9e7e 208 SMART SM01390 3 97 7.3E-50 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFE_0353 509274423e13179bb42d7fe3804e9e7e 208 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 208 1.6E-70 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFE_0353 509274423e13179bb42d7fe3804e9e7e 208 SMART SM00363 98 156 6.7E-17 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 Pfam PF00773 RNB domain 269 595 3.5E-103 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 SUPERFAMILY SSF50249 642 724 3.88E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 Pfam PF00575 S1 RNA binding domain 641 723 3.7E-10 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 SMART SM00316 642 725 3.5E-13 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 SMART SM00316 89 151 59.0 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 Hamap MF_01895 Ribonuclease R [rnr]. 48 725 55.618 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 Gene3D G3DSA:2.40.50.140 645 746 1.5E-22 T 12-10-2018 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 Pfam PF08206 Ribonuclease B OB domain 96 153 1.1E-20 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 SMART SM00357 95 154 2.3E-19 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 TIGRFAM TIGR02063 RNase_R: ribonuclease R 30 723 1.5E-250 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 76 724 2.3E-219 T 12-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 SUPERFAMILY SSF50249 196 642 3.18E-138 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 SMART SM00955 269 596 2.9E-163 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 SUPERFAMILY SSF50249 76 156 5.71E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 Gene3D G3DSA:2.40.50.140 84 156 4.7E-19 T 12-10-2018 AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 ProSitePatterns PS01175 Ribonuclease II family signature. 563 587 - T 12-10-2018 IPR022966 Ribonuclease II/R, conserved site AFE_1891 04b120c5494cdde6b0fdc0684d0491ca 746 Pfam PF08461 Ribonuclease R winged-helix domain 32 83 1.9E-6 T 12-10-2018 IPR013668 Ribonuclease R winged-helix domain AFE_1997 fe94ec4cb7c73111df9c6cea8fc9e5d5 237 Pfam PF03472 Autoinducer binding domain 18 159 9.2E-40 T 12-10-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain AFE_1997 fe94ec4cb7c73111df9c6cea8fc9e5d5 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 206 218 9.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFE_1997 fe94ec4cb7c73111df9c6cea8fc9e5d5 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 206 9.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFE_1997 fe94ec4cb7c73111df9c6cea8fc9e5d5 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 190 9.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFE_1997 fe94ec4cb7c73111df9c6cea8fc9e5d5 237 SMART SM00421 173 230 7.7E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFE_1997 fe94ec4cb7c73111df9c6cea8fc9e5d5 237 Pfam PF00196 Bacterial regulatory proteins, luxR family 175 228 1.1E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFE_1997 fe94ec4cb7c73111df9c6cea8fc9e5d5 237 SUPERFAMILY SSF46894 161 236 3.06E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFE_1997 fe94ec4cb7c73111df9c6cea8fc9e5d5 237 Gene3D G3DSA:1.10.10.10 169 237 8.9E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1997 fe94ec4cb7c73111df9c6cea8fc9e5d5 237 SUPERFAMILY SSF75516 4 166 5.75E-43 T 12-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily AFE_1997 fe94ec4cb7c73111df9c6cea8fc9e5d5 237 Gene3D G3DSA:3.30.450.80 1 168 5.3E-54 T 12-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily AFE_0833 e84bd4c01400660382e7a62fbcb420e9 332 Pfam PF00589 Phage integrase family 126 293 6.0E-35 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_0833 e84bd4c01400660382e7a62fbcb420e9 332 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 16 96 1.7E-8 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFE_0833 e84bd4c01400660382e7a62fbcb420e9 332 SUPERFAMILY SSF56349 125 303 1.85E-45 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_0833 e84bd4c01400660382e7a62fbcb420e9 332 Gene3D G3DSA:1.10.150.130 9 106 6.1E-11 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFE_0833 e84bd4c01400660382e7a62fbcb420e9 332 Gene3D G3DSA:1.10.443.10 125 302 2.1E-47 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_0509 e84bd4c01400660382e7a62fbcb420e9 332 Pfam PF00589 Phage integrase family 126 293 6.0E-35 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_0509 e84bd4c01400660382e7a62fbcb420e9 332 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 16 96 1.7E-8 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFE_0509 e84bd4c01400660382e7a62fbcb420e9 332 SUPERFAMILY SSF56349 125 303 1.85E-45 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_0509 e84bd4c01400660382e7a62fbcb420e9 332 Gene3D G3DSA:1.10.150.130 9 106 6.1E-11 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFE_0509 e84bd4c01400660382e7a62fbcb420e9 332 Gene3D G3DSA:1.10.443.10 125 302 2.1E-47 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_2399 e84bd4c01400660382e7a62fbcb420e9 332 Pfam PF00589 Phage integrase family 126 293 6.0E-35 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_2399 e84bd4c01400660382e7a62fbcb420e9 332 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 16 96 1.7E-8 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFE_2399 e84bd4c01400660382e7a62fbcb420e9 332 SUPERFAMILY SSF56349 125 303 1.85E-45 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_2399 e84bd4c01400660382e7a62fbcb420e9 332 Gene3D G3DSA:1.10.150.130 9 106 6.1E-11 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFE_2399 e84bd4c01400660382e7a62fbcb420e9 332 Gene3D G3DSA:1.10.443.10 125 302 2.1E-47 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_0797 726ba0b9e21592edd7dc61db984073bc 88 SUPERFAMILY SSF47336 11 87 2.75E-10 T 12-10-2018 IPR036736 ACP-like superfamily AFE_0797 726ba0b9e21592edd7dc61db984073bc 88 Pfam PF00550 Phosphopantetheine attachment site 18 81 5.0E-7 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFE_0797 726ba0b9e21592edd7dc61db984073bc 88 Gene3D G3DSA:1.10.1200.10 9 86 1.9E-12 T 12-10-2018 IPR036736 ACP-like superfamily AFE_1342 e42a07430e91b71a67233db05f898380 332 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 8 327 1.0E-133 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 AFE_1342 e42a07430e91b71a67233db05f898380 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 257 1.4E-57 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFE_1342 e42a07430e91b71a67233db05f898380 332 SUPERFAMILY SSF51735 9 329 2.14E-93 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1342 e42a07430e91b71a67233db05f898380 332 Gene3D G3DSA:3.90.25.10 178 311 8.8E-129 T 12-10-2018 AFE_1342 e42a07430e91b71a67233db05f898380 332 Gene3D G3DSA:3.40.50.720 9 257 8.8E-129 T 12-10-2018 AFE_0289 1d70c1ecbc1deda202bf6566d18e1236 261 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 25 259 38.517 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFE_0289 1d70c1ecbc1deda202bf6566d18e1236 261 Pfam PF01209 ubiE/COQ5 methyltransferase family 29 258 3.4E-91 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFE_0289 1d70c1ecbc1deda202bf6566d18e1236 261 SUPERFAMILY SSF53335 23 260 6.5E-49 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0289 1d70c1ecbc1deda202bf6566d18e1236 261 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 34 257 4.3E-83 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFE_0289 1d70c1ecbc1deda202bf6566d18e1236 261 Gene3D G3DSA:3.40.50.150 40 260 1.1E-77 T 12-10-2018 AFE_0289 1d70c1ecbc1deda202bf6566d18e1236 261 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 45 60 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 AFE_0335 00042cff244b1864f948cc617b9d0d9f 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 16.01 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0335 00042cff244b1864f948cc617b9d0d9f 65 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 12-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0335 00042cff244b1864f948cc617b9d0d9f 65 Gene3D G3DSA:1.10.287.310 1 63 1.7E-20 T 12-10-2018 AFE_0335 00042cff244b1864f948cc617b9d0d9f 65 SUPERFAMILY SSF46561 1 61 1.44E-16 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0335 00042cff244b1864f948cc617b9d0d9f 65 Pfam PF00831 Ribosomal L29 protein 8 58 1.9E-17 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0335 00042cff244b1864f948cc617b9d0d9f 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 14 58 4.5E-16 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0575 3c18927a4813b7bf9c4a540d6e5b1f08 444 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 26 439 4.5E-88 T 12-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 AFE_0575 3c18927a4813b7bf9c4a540d6e5b1f08 444 Gene3D G3DSA:1.20.1600.10 27 443 9.3E-99 T 12-10-2018 AFE_0575 3c18927a4813b7bf9c4a540d6e5b1f08 444 Pfam PF02321 Outer membrane efflux protein 243 424 7.7E-28 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_0575 3c18927a4813b7bf9c4a540d6e5b1f08 444 Pfam PF02321 Outer membrane efflux protein 30 217 3.5E-30 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_0575 3c18927a4813b7bf9c4a540d6e5b1f08 444 SUPERFAMILY SSF56954 8 426 1.23E-80 T 12-10-2018 AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 Gene3D G3DSA:2.40.30.170 255 334 8.7E-51 T 12-10-2018 AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 Gene3D G3DSA:2.40.30.170 119 132 4.7E-13 T 12-10-2018 AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 Gene3D G3DSA:2.40.50.100 216 254 8.7E-51 T 12-10-2018 AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 Gene3D G3DSA:2.40.50.100 133 167 4.7E-13 T 12-10-2018 AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 Gene3D G3DSA:1.10.287.470 168 183 4.7E-13 T 12-10-2018 AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 Gene3D G3DSA:1.10.287.470 190 215 8.7E-51 T 12-10-2018 AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 SUPERFAMILY SSF111369 131 332 2.35E-20 T 12-10-2018 AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 106 398 1.4E-39 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 116 328 7.9E-78 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 Gene3D G3DSA:2.40.420.20 335 393 8.7E-51 T 12-10-2018 AFE_2433 50fc838aa2fd04560cfe2df72c24a00f 482 Gene3D G3DSA:2.40.420.20 108 118 4.7E-13 T 12-10-2018 AFE_0338 4d08e438b09f37c96b677717349b9655 106 SMART SM00739 3 30 3.3E-5 T 12-10-2018 IPR005824 KOW AFE_0338 4d08e438b09f37c96b677717349b9655 106 Pfam PF00467 KOW motif 6 37 3.5E-8 T 12-10-2018 IPR005824 KOW AFE_0338 4d08e438b09f37c96b677717349b9655 106 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 39 103 1.8E-25 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0338 4d08e438b09f37c96b677717349b9655 106 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 103 4.5E-39 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0338 4d08e438b09f37c96b677717349b9655 106 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0338 4d08e438b09f37c96b677717349b9655 106 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 97 21.934 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0338 4d08e438b09f37c96b677717349b9655 106 SUPERFAMILY SSF50104 2 102 5.64E-35 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFE_0338 4d08e438b09f37c96b677717349b9655 106 Gene3D G3DSA:2.30.30.30 1 104 8.2E-37 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFE_2034 1dbaf54ead9d0546b5e9921304eb5fdd 358 Gene3D G3DSA:2.130.10.10 176 354 1.8E-15 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_2034 1dbaf54ead9d0546b5e9921304eb5fdd 358 Gene3D G3DSA:2.130.10.10 53 175 4.2E-15 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_2034 1dbaf54ead9d0546b5e9921304eb5fdd 358 SUPERFAMILY SSF51004 75 340 1.12E-28 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 Pfam PF14559 Tetratricopeptide repeat 366 430 8.7E-9 T 12-10-2018 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SMART SM00028 388 421 0.049 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SMART SM00028 320 353 0.53 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SMART SM00028 286 319 29.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SMART SM00028 116 149 0.049 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SMART SM00028 48 81 59.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SMART SM00028 354 387 40.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SMART SM00028 218 251 42.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SMART SM00028 462 495 24.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SMART SM00028 150 183 0.12 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SMART SM00028 82 115 0.09 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SUPERFAMILY SSF48452 379 491 1.22E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 Gene3D G3DSA:3.40.50.300 519 761 2.7E-61 T 12-10-2018 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SUPERFAMILY SSF48452 21 308 2.06E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 Pfam PF13469 Sulfotransferase family 531 711 1.4E-35 T 12-10-2018 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SUPERFAMILY SSF48452 262 413 1.07E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 SUPERFAMILY SSF52540 528 747 1.33E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 Pfam PF13374 Tetratricopeptide repeat 223 248 7.2E-4 T 12-10-2018 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 Gene3D G3DSA:1.25.40.10 1 318 8.2E-55 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 265 344 1.8E-7 T 12-10-2018 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 Gene3D G3DSA:1.25.40.10 322 497 1.8E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 Pfam PF13432 Tetratricopeptide repeat 123 183 8.8E-9 T 12-10-2018 AFE_2716 d616754e39507b6b4c53ca23f8e386e0 762 Pfam PF13432 Tetratricopeptide repeat 61 114 3.4E-5 T 12-10-2018 AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 298 349 1.8E-16 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 46 5.6E-8 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 SUPERFAMILY SSF52156 653 782 8.63E-38 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 ProSitePatterns PS01176 Initiation factor 2 signature. 826 848 - T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 SUPERFAMILY SSF50447 548 630 1.23E-22 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 293 874 2.6E-259 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 2 873 17.34 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 SUPERFAMILY SSF50447 777 873 8.44E-32 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Gene3D G3DSA:2.40.30.10 777 874 4.0E-34 T 12-10-2018 AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 SUPERFAMILY SSF46955 3 50 1.04E-7 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 378 534 6.8E-31 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Pfam PF00009 Elongation factor Tu GTP binding domain 380 536 3.6E-33 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Gene3D G3DSA:3.40.50.10050 669 776 3.4E-38 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 60 98 1.9E-15 T 12-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 SUPERFAMILY SSF52540 373 544 1.71E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Pfam PF11987 Translation-initiation factor 2 661 765 5.3E-37 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Gene3D G3DSA:2.40.30.10 547 664 7.1E-36 T 12-10-2018 AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Gene3D G3DSA:3.30.56.50 1 50 8.5E-8 T 12-10-2018 AFE_0391 23329c3c3762d2e21bad2a85ffac951f 875 Gene3D G3DSA:3.40.50.300 373 546 2.0E-70 T 12-10-2018 AFE_0316 ce071b275c7303a7a302ed7539c77d3a 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0316 ce071b275c7303a7a302ed7539c77d3a 230 SUPERFAMILY SSF56808 6 226 3.66E-79 T 12-10-2018 IPR023674 Ribosomal protein L1-like AFE_0316 ce071b275c7303a7a302ed7539c77d3a 230 Pfam PF00687 Ribosomal protein L1p/L10e family 30 220 2.6E-49 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein AFE_0316 ce071b275c7303a7a302ed7539c77d3a 230 PIRSF PIRSF002155 1 227 1.4E-77 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0316 ce071b275c7303a7a302ed7539c77d3a 230 Gene3D G3DSA:3.30.190.20 21 225 5.0E-77 T 12-10-2018 AFE_0316 ce071b275c7303a7a302ed7539c77d3a 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 3 229 42.451 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 AFE_0316 ce071b275c7303a7a302ed7539c77d3a 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 4 227 5.9E-101 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 AFE_0316 ce071b275c7303a7a302ed7539c77d3a 230 Gene3D G3DSA:3.40.50.790 68 159 5.0E-77 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich AFE_0637 84727e5e9e78f697cb9b7eebba1ae29f 400 Pfam PF07690 Major Facilitator Superfamily 13 290 1.8E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_0637 84727e5e9e78f697cb9b7eebba1ae29f 400 PRINTS PR01036 Tetracycline resistance protein TetB signature 72 94 5.8E-5 T 12-10-2018 AFE_0637 84727e5e9e78f697cb9b7eebba1ae29f 400 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 5.8E-5 T 12-10-2018 AFE_0637 84727e5e9e78f697cb9b7eebba1ae29f 400 Gene3D G3DSA:1.20.1250.20 1 379 2.1E-71 T 12-10-2018 AFE_0637 84727e5e9e78f697cb9b7eebba1ae29f 400 SUPERFAMILY SSF103473 5 380 6.02E-59 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_0099 26048a4a6cc2be87bd1313934ebae39f 148 SUPERFAMILY SSF52499 5 147 4.84E-11 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFE_0099 26048a4a6cc2be87bd1313934ebae39f 148 Pfam PF00857 Isochorismatase family 6 131 2.7E-5 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFE_0099 26048a4a6cc2be87bd1313934ebae39f 148 Gene3D G3DSA:3.40.50.850 1 148 3.4E-7 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFE_1458 f753f77de03d41aa34dccafc877281ba 369 Gene3D G3DSA:3.90.1150.10 252 368 2.6E-35 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_1458 f753f77de03d41aa34dccafc877281ba 369 PIRSF PIRSF000390 7 369 2.8E-106 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFE_1458 f753f77de03d41aa34dccafc877281ba 369 SUPERFAMILY SSF53383 19 367 4.17E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_1458 f753f77de03d41aa34dccafc877281ba 369 Gene3D G3DSA:3.40.640.10 2 247 2.3E-91 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_1458 f753f77de03d41aa34dccafc877281ba 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 21 363 5.2E-120 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFE_2266 e63d5b914d262ab64c866db93875aa92 193 Gene3D G3DSA:3.40.630.30 10 177 1.6E-22 T 12-10-2018 AFE_2266 e63d5b914d262ab64c866db93875aa92 193 Pfam PF00583 Acetyltransferase (GNAT) family 67 157 3.7E-11 T 12-10-2018 IPR000182 GNAT domain AFE_2266 e63d5b914d262ab64c866db93875aa92 193 SUPERFAMILY SSF55729 20 168 1.17E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_2303 5ee1dac7e1b1748a2544084655e3bff6 945 Pfam PF10282 Lactonase, 7-bladed beta-propeller 205 424 1.2E-5 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller AFE_2303 5ee1dac7e1b1748a2544084655e3bff6 945 Gene3D G3DSA:2.130.10.10 77 173 7.4E-6 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_2303 5ee1dac7e1b1748a2544084655e3bff6 945 Gene3D G3DSA:2.130.10.10 190 246 7.5E-8 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_2303 5ee1dac7e1b1748a2544084655e3bff6 945 Gene3D G3DSA:2.130.10.10 248 429 1.5E-17 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_2303 5ee1dac7e1b1748a2544084655e3bff6 945 Gene3D G3DSA:3.40.720.10 743 882 6.1E-7 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_2303 5ee1dac7e1b1748a2544084655e3bff6 945 Gene3D G3DSA:3.40.720.10 499 606 3.6E-5 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_2303 5ee1dac7e1b1748a2544084655e3bff6 945 SUPERFAMILY SSF51004 119 419 4.45E-30 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily AFE_0315 fdcdd432f1f6303415289f16d4584500 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 12-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0315 fdcdd432f1f6303415289f16d4584500 142 SMART SM00649 9 141 9.6E-80 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AFE_0315 fdcdd432f1f6303415289f16d4584500 142 Gene3D G3DSA:3.30.1550.10 2 72 1.4E-32 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily AFE_0315 fdcdd432f1f6303415289f16d4584500 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 1.0E-26 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal AFE_0315 fdcdd432f1f6303415289f16d4584500 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 2.6E-63 T 12-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0315 fdcdd432f1f6303415289f16d4584500 142 Gene3D G3DSA:1.10.10.250 73 141 1.7E-27 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily AFE_0315 fdcdd432f1f6303415289f16d4584500 142 SUPERFAMILY SSF54747 3 73 5.36E-29 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily AFE_0315 fdcdd432f1f6303415289f16d4584500 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 6.5E-24 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AFE_0315 fdcdd432f1f6303415289f16d4584500 142 SUPERFAMILY SSF46906 68 141 1.1E-25 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily AFE_0315 fdcdd432f1f6303415289f16d4584500 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 30.996 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AFE_0315 fdcdd432f1f6303415289f16d4584500 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-14 T 12-10-2018 AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 SUPERFAMILY SSF51161 252 434 8.0E-54 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 393 427 5.3E-9 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 315 349 1.7E-7 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 265 296 7.2E-5 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 Gene3D G3DSA:3.90.550.10 3 225 2.2E-56 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 SUPERFAMILY SSF53448 5 245 9.39E-56 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 452 1.2E-177 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 Pfam PF12804 MobA-like NTP transferase domain 6 119 6.1E-25 T 12-10-2018 IPR025877 MobA-like NTP transferase AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 450 39.444 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 Gene3D G3DSA:2.160.10.10 227 454 8.4E-70 T 12-10-2018 AFE_3201 bcdca03e4ac8b39ae968a5fc5e3d2b63 455 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 401 429 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFE_3058 f5c98a8a98cc7d0b02229087836cfea9 424 Gene3D G3DSA:3.20.20.140 57 368 2.1E-109 T 12-10-2018 AFE_3058 f5c98a8a98cc7d0b02229087836cfea9 424 SUPERFAMILY SSF51338 2 423 6.05E-24 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_3058 f5c98a8a98cc7d0b02229087836cfea9 424 Pfam PF01979 Amidohydrolase family 148 420 4.2E-15 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFE_3058 f5c98a8a98cc7d0b02229087836cfea9 424 SUPERFAMILY SSF51556 56 366 1.25E-82 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFE_3058 f5c98a8a98cc7d0b02229087836cfea9 424 Gene3D G3DSA:2.30.40.10 9 421 2.1E-109 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_3058 f5c98a8a98cc7d0b02229087836cfea9 424 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 22 422 5.5E-86 T 12-10-2018 AFE_2206 2361c02b834377d3d507ff3a7f63196d 275 SUPERFAMILY SSF51690 109 273 4.32E-57 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFE_2206 2361c02b834377d3d507ff3a7f63196d 275 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 109 273 1.3E-56 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 AFE_2206 2361c02b834377d3d507ff3a7f63196d 275 PIRSF PIRSF006250 1 275 1.1E-96 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 AFE_2206 2361c02b834377d3d507ff3a7f63196d 275 Gene3D G3DSA:3.20.20.70 117 264 6.4E-108 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2206 2361c02b834377d3d507ff3a7f63196d 275 SUPERFAMILY SSF54675 3 107 1.18E-30 T 12-10-2018 AFE_2206 2361c02b834377d3d507ff3a7f63196d 275 Gene3D G3DSA:3.90.1170.20 5 273 6.4E-108 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 AFE_2206 2361c02b834377d3d507ff3a7f63196d 275 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 273 7.0E-94 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 AFE_2206 2361c02b834377d3d507ff3a7f63196d 275 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 106 1.4E-25 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFE_1972 1907cd7ec6abec0d5ba109be701c8376 363 SUPERFAMILY SSF103263 4 352 9.16E-144 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFE_1972 1907cd7ec6abec0d5ba109be701c8376 363 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFE_1972 1907cd7ec6abec0d5ba109be701c8376 363 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFE_1972 1907cd7ec6abec0d5ba109be701c8376 363 Pfam PF01264 Chorismate synthase 10 345 3.3E-140 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFE_1972 1907cd7ec6abec0d5ba109be701c8376 363 Gene3D G3DSA:3.60.150.10 1 362 9.1E-154 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFE_1972 1907cd7ec6abec0d5ba109be701c8376 363 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFE_1972 1907cd7ec6abec0d5ba109be701c8376 363 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 36.82 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFE_1972 1907cd7ec6abec0d5ba109be701c8376 363 PIRSF PIRSF001456 3 358 1.5E-138 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFE_1972 1907cd7ec6abec0d5ba109be701c8376 363 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 2.6E-138 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFE_0715 4eac1d2fe10b8005f8be1498b5421b76 381 Gene3D G3DSA:3.40.50.11750 30 263 1.0E-110 T 12-10-2018 AFE_0715 4eac1d2fe10b8005f8be1498b5421b76 381 PIRSF PIRSF005622 1 371 1.9E-160 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFE_0715 4eac1d2fe10b8005f8be1498b5421b76 381 Gene3D G3DSA:3.40.50.11740 66 304 1.0E-110 T 12-10-2018 AFE_0715 4eac1d2fe10b8005f8be1498b5421b76 381 Gene3D G3DSA:1.10.10.2140 318 369 4.4E-23 T 12-10-2018 AFE_0715 4eac1d2fe10b8005f8be1498b5421b76 381 Pfam PF01924 Hydrogenase formation hypA family 20 367 4.1E-156 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFE_0715 4eac1d2fe10b8005f8be1498b5421b76 381 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 2 369 2.5E-151 T 12-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFE_1850 a8f4cd9ea3a29037d262de4347738d22 77 SUPERFAMILY SSF69118 21 69 2.4E-9 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFE_1850 a8f4cd9ea3a29037d262de4347738d22 77 Gene3D G3DSA:1.20.1290.10 18 70 1.3E-8 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFE_2363 43b360973aeb978c40d9aed71c7d2a54 94 Pfam PF00462 Glutaredoxin 8 67 2.0E-18 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFE_2363 43b360973aeb978c40d9aed71c7d2a54 94 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 7 86 7.6E-32 T 12-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 AFE_2363 43b360973aeb978c40d9aed71c7d2a54 94 Gene3D G3DSA:3.40.30.10 2 88 3.5E-26 T 12-10-2018 AFE_2363 43b360973aeb978c40d9aed71c7d2a54 94 SUPERFAMILY SSF52833 4 89 2.49E-25 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_2363 43b360973aeb978c40d9aed71c7d2a54 94 PRINTS PR00160 Glutaredoxin signature 50 63 1.6E-14 T 12-10-2018 IPR014025 Glutaredoxin subgroup AFE_2363 43b360973aeb978c40d9aed71c7d2a54 94 PRINTS PR00160 Glutaredoxin signature 7 25 1.6E-14 T 12-10-2018 IPR014025 Glutaredoxin subgroup AFE_2363 43b360973aeb978c40d9aed71c7d2a54 94 PRINTS PR00160 Glutaredoxin signature 64 77 1.6E-14 T 12-10-2018 IPR014025 Glutaredoxin subgroup AFE_2363 43b360973aeb978c40d9aed71c7d2a54 94 ProSitePatterns PS00195 Glutaredoxin active site. 9 25 - T 12-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 AFE_1355 8293865966268c968cf37ff3b4012205 413 Pfam PF00534 Glycosyl transferases group 1 226 383 4.1E-29 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1355 8293865966268c968cf37ff3b4012205 413 Gene3D G3DSA:3.40.50.2000 61 214 9.0E-12 T 12-10-2018 AFE_1355 8293865966268c968cf37ff3b4012205 413 Pfam PF13439 Glycosyltransferase Family 4 63 204 3.0E-10 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_1355 8293865966268c968cf37ff3b4012205 413 Gene3D G3DSA:3.40.50.2000 215 386 1.9E-39 T 12-10-2018 AFE_1355 8293865966268c968cf37ff3b4012205 413 SUPERFAMILY SSF53756 63 405 1.26E-67 T 12-10-2018 AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 3 1190 20.663 T 12-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 Gene3D G3DSA:3.40.50.300 470 870 1.9E-130 T 12-10-2018 AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 Gene3D G3DSA:1.10.486.10 614 759 1.9E-130 T 12-10-2018 AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 5 1189 4.6E-262 T 12-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 Gene3D G3DSA:3.90.320.10 918 1194 8.2E-70 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 SUPERFAMILY SSF52980 926 1189 8.04E-61 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 SUPERFAMILY SSF52540 11 850 3.04E-97 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 Gene3D G3DSA:3.40.50.300 5 459 2.5E-129 T 12-10-2018 AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 Pfam PF12705 PD-(D/E)XK nuclease superfamily 963 1142 9.9E-5 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 Gene3D G3DSA:1.10.3170.10 159 369 2.5E-129 T 12-10-2018 AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 Pfam PF13361 UvrD-like helicase C-terminal domain 666 846 1.6E-11 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFE_2932 1a581f5cdc59a45523d1aba92140e631 1198 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 458 6.2E-50 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFE_3107 f6cf9325698adb815c9b9c59dc774733 234 SUPERFAMILY SSF46626 56 131 2.01E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_3107 f6cf9325698adb815c9b9c59dc774733 234 Gene3D G3DSA:1.10.760.10 51 129 8.9E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_3107 f6cf9325698adb815c9b9c59dc774733 234 PIRSF PIRSF000005 1 230 5.2E-68 T 12-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 AFE_3107 f6cf9325698adb815c9b9c59dc774733 234 Pfam PF00034 Cytochrome c 141 228 4.4E-5 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3107 f6cf9325698adb815c9b9c59dc774733 234 Pfam PF00034 Cytochrome c 56 128 1.8E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3107 f6cf9325698adb815c9b9c59dc774733 234 Gene3D G3DSA:1.10.760.10 134 228 2.3E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_3107 f6cf9325698adb815c9b9c59dc774733 234 SUPERFAMILY SSF46626 137 228 8.0E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_2860 e2574be2e12e9410af7867b40b9d2887 163 Gene3D G3DSA:3.40.50.2300 1 138 1.1E-35 T 12-10-2018 AFE_2860 e2574be2e12e9410af7867b40b9d2887 163 SUPERFAMILY SSF52788 5 138 3.79E-36 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AFE_2860 e2574be2e12e9410af7867b40b9d2887 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 135 8.0E-19 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFE_2860 e2574be2e12e9410af7867b40b9d2887 163 SMART SM00226 4 138 1.7E-33 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFE_2254 133c1c00185f884c0327ea562bee18e5 688 SUPERFAMILY SSF56601 227 573 4.9E-63 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_2254 133c1c00185f884c0327ea562bee18e5 688 Gene3D G3DSA:3.40.710.10 285 593 8.0E-55 T 12-10-2018 AFE_2254 133c1c00185f884c0327ea562bee18e5 688 Pfam PF00905 Penicillin binding protein transpeptidase domain 316 547 1.9E-10 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFE_2254 133c1c00185f884c0327ea562bee18e5 688 Pfam PF00912 Transglycosylase 79 244 1.1E-38 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_2254 133c1c00185f884c0327ea562bee18e5 688 Gene3D G3DSA:1.10.3810.10 62 261 5.8E-44 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_2254 133c1c00185f884c0327ea562bee18e5 688 SUPERFAMILY SSF53955 62 276 6.19E-53 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFE_2254 133c1c00185f884c0327ea562bee18e5 688 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 594 664 1.8E-8 T 12-10-2018 IPR009647 Penicillin-binding, C-terminal KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_2254 133c1c00185f884c0327ea562bee18e5 688 ProSitePatterns PS00104 EPSP synthase signature 1. 449 463 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFE_1657 7dddd49983fb7709e5c0e412173d6b26 556 Gene3D G3DSA:3.40.50.2030 382 552 1.5E-58 T 12-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFE_1657 7dddd49983fb7709e5c0e412173d6b26 556 Gene3D G3DSA:1.20.1270.20 153 235 1.6E-26 T 12-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFE_1657 7dddd49983fb7709e5c0e412173d6b26 556 Gene3D G3DSA:3.40.50.2030 237 381 1.3E-62 T 12-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFE_1657 7dddd49983fb7709e5c0e412173d6b26 556 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 553 21.742 T 12-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 AFE_1657 7dddd49983fb7709e5c0e412173d6b26 556 Pfam PF03063 Prismane/CO dehydrogenase family 1 548 1.9E-153 T 12-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 AFE_1657 7dddd49983fb7709e5c0e412173d6b26 556 SUPERFAMILY SSF56821 1 552 3.79E-184 T 12-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 AFE_1657 7dddd49983fb7709e5c0e412173d6b26 556 Gene3D G3DSA:1.20.1270.20 1 143 4.8E-37 T 12-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFE_1657 7dddd49983fb7709e5c0e412173d6b26 556 PIRSF PIRSF000076 1 554 4.4E-231 T 12-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 AFE_1657 7dddd49983fb7709e5c0e412173d6b26 556 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 551 1.1E-249 T 12-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 AFE_0971 5be6256fdf62fce8223a9fe9be1c3087 188 SUPERFAMILY SSF54523 18 120 1.96E-13 T 12-10-2018 AFE_0971 5be6256fdf62fce8223a9fe9be1c3087 188 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 17 38 1.2E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFE_0971 5be6256fdf62fce8223a9fe9be1c3087 188 Pfam PF12019 Type II transport protein GspH 53 152 1.4E-5 T 12-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 AFE_0971 5be6256fdf62fce8223a9fe9be1c3087 188 Gene3D G3DSA:3.30.700.10 18 186 4.3E-12 T 12-10-2018 AFE_0971 5be6256fdf62fce8223a9fe9be1c3087 188 Pfam PF07963 Prokaryotic N-terminal methylation motif 17 37 1.2E-4 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFE_2589 3eec4aca90bff9d7fe77f197f9dba7e5 184 Gene3D G3DSA:3.40.80.10 4 182 1.3E-49 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFE_2589 3eec4aca90bff9d7fe77f197f9dba7e5 184 SMART SM00644 18 168 4.5E-37 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFE_2589 3eec4aca90bff9d7fe77f197f9dba7e5 184 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 29 169 1.2E-22 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFE_2589 3eec4aca90bff9d7fe77f197f9dba7e5 184 SUPERFAMILY SSF55846 6 180 3.53E-56 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFE_0226 6400c7c34ecf1819b162d01cfb4beaeb 408 Gene3D G3DSA:3.60.70.12 10 278 1.1E-87 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFE_0226 6400c7c34ecf1819b162d01cfb4beaeb 408 Pfam PF01960 ArgJ family 20 408 2.2E-138 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFE_0226 6400c7c34ecf1819b162d01cfb4beaeb 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 152.504 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFE_0226 6400c7c34ecf1819b162d01cfb4beaeb 408 Gene3D G3DSA:3.10.20.340 279 408 1.2E-39 T 12-10-2018 AFE_0226 6400c7c34ecf1819b162d01cfb4beaeb 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 22 406 3.0E-115 T 12-10-2018 AFE_0226 6400c7c34ecf1819b162d01cfb4beaeb 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 10 408 4.1E-119 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFE_0226 6400c7c34ecf1819b162d01cfb4beaeb 408 SUPERFAMILY SSF56266 14 405 2.75E-132 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFE_1392 dbcc67d07636beae526e22375021b1ee 529 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 4 502 9.6E-169 T 12-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFE_1392 dbcc67d07636beae526e22375021b1ee 529 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 506 5.1E-8 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFE_1392 dbcc67d07636beae526e22375021b1ee 529 Gene3D G3DSA:1.20.58.100 413 519 1.8E-19 T 12-10-2018 AFE_1392 dbcc67d07636beae526e22375021b1ee 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 340 362 7.8E-10 T 12-10-2018 AFE_1392 dbcc67d07636beae526e22375021b1ee 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.8E-10 T 12-10-2018 AFE_1392 dbcc67d07636beae526e22375021b1ee 529 Gene3D G3DSA:3.50.50.60 5 385 7.1E-148 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1392 dbcc67d07636beae526e22375021b1ee 529 SUPERFAMILY SSF46977 420 506 8.63E-21 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFE_1392 dbcc67d07636beae526e22375021b1ee 529 Gene3D G3DSA:3.90.700.10 233 343 7.1E-148 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFE_1392 dbcc67d07636beae526e22375021b1ee 529 SUPERFAMILY SSF56425 223 337 7.03E-37 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFE_1392 dbcc67d07636beae526e22375021b1ee 529 SUPERFAMILY SSF51905 3 390 2.72E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1392 dbcc67d07636beae526e22375021b1ee 529 Pfam PF00890 FAD binding domain 5 377 7.4E-92 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFE_0723 66447e9ede89bff1d949405166ce2e20 123 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 85 1.5E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0723 66447e9ede89bff1d949405166ce2e20 123 Gene3D G3DSA:1.10.10.10 2 122 2.8E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0723 66447e9ede89bff1d949405166ce2e20 123 SUPERFAMILY SSF46785 6 102 1.46E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 Gene3D G3DSA:2.60.40.420 34 187 8.9E-57 T 12-10-2018 IPR008972 Cupredoxin AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 PRINTS PR00158 Rusticyanin signature 110 129 9.2E-84 T 12-10-2018 IPR001243 Rusticyanin GO:0005507|GO:0009055 AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 PRINTS PR00158 Rusticyanin signature 70 87 9.2E-84 T 12-10-2018 IPR001243 Rusticyanin GO:0005507|GO:0009055 AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 PRINTS PR00158 Rusticyanin signature 48 68 9.2E-84 T 12-10-2018 IPR001243 Rusticyanin GO:0005507|GO:0009055 AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 PRINTS PR00158 Rusticyanin signature 89 108 9.2E-84 T 12-10-2018 IPR001243 Rusticyanin GO:0005507|GO:0009055 AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 PRINTS PR00158 Rusticyanin signature 136 154 9.2E-84 T 12-10-2018 IPR001243 Rusticyanin GO:0005507|GO:0009055 AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 PRINTS PR00158 Rusticyanin signature 157 179 9.2E-84 T 12-10-2018 IPR001243 Rusticyanin GO:0005507|GO:0009055 AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 TIGRFAM TIGR03095 rusti_cyanin: rusticyanin 46 187 3.4E-71 T 12-10-2018 IPR001243 Rusticyanin GO:0005507|GO:0009055 AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 ProSitePatterns PS00079 Multicopper oxidases signature 1. 164 184 - T 12-10-2018 IPR033138 Multicopper oxidases, conserved site AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 163 180 - T 12-10-2018 IPR028871 Blue (type 1) copper protein, binding site AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 96 187 6.2E-6 T 12-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 AFE_3146 9cff141ef95246d2bab58e902f3f0573 187 SUPERFAMILY SSF49503 37 186 2.21E-24 T 12-10-2018 IPR008972 Cupredoxin AFE_2166 3f8e229df39576a786365c6a7a49d079 445 Pfam PF13437 HlyD family secretion protein 269 352 1.3E-12 T 12-10-2018 AFE_2166 3f8e229df39576a786365c6a7a49d079 445 Pfam PF13533 Biotin-lipoyl like 75 104 2.0E-5 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain AFE_2166 3f8e229df39576a786365c6a7a49d079 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 280 301 9.0E-14 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2166 3f8e229df39576a786365c6a7a49d079 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 313 337 9.0E-14 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2166 3f8e229df39576a786365c6a7a49d079 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 389 404 9.0E-14 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_2166 3f8e229df39576a786365c6a7a49d079 445 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 84 104 9.0E-14 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFE_0543 838f97a25cc4c9bf900c40b93121329f 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 27.704 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFE_0543 838f97a25cc4c9bf900c40b93121329f 96 SMART SM00883 2 94 7.5E-58 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFE_0543 838f97a25cc4c9bf900c40b93121329f 96 SUPERFAMILY SSF50129 1 95 4.36E-35 T 12-10-2018 IPR011032 GroES-like superfamily AFE_0543 838f97a25cc4c9bf900c40b93121329f 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 AFE_0543 838f97a25cc4c9bf900c40b93121329f 96 PRINTS PR00297 10kDa chaperonin signature 25 46 1.9E-32 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFE_0543 838f97a25cc4c9bf900c40b93121329f 96 PRINTS PR00297 10kDa chaperonin signature 81 94 1.9E-32 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFE_0543 838f97a25cc4c9bf900c40b93121329f 96 PRINTS PR00297 10kDa chaperonin signature 3 18 1.9E-32 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFE_0543 838f97a25cc4c9bf900c40b93121329f 96 PRINTS PR00297 10kDa chaperonin signature 60 72 1.9E-32 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFE_0543 838f97a25cc4c9bf900c40b93121329f 96 Gene3D G3DSA:2.30.33.40 1 96 3.3E-38 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 AFE_0543 838f97a25cc4c9bf900c40b93121329f 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 2.7E-34 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFE_0570 70e19d81a7565c00f412f520afe2a971 446 Gene3D G3DSA:3.50.50.60 4 436 3.6E-132 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0570 70e19d81a7565c00f412f520afe2a971 446 Gene3D G3DSA:1.10.3110.10 97 197 3.6E-132 T 12-10-2018 AFE_0570 70e19d81a7565c00f412f520afe2a971 446 SUPERFAMILY SSF54373 287 394 1.65E-26 T 12-10-2018 AFE_0570 70e19d81a7565c00f412f520afe2a971 446 Gene3D G3DSA:3.90.660.20 39 394 3.6E-132 T 12-10-2018 AFE_0570 70e19d81a7565c00f412f520afe2a971 446 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 1 440 4.7E-83 T 12-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_0570 70e19d81a7565c00f412f520afe2a971 446 Pfam PF01593 Flavin containing amine oxidoreductase 11 436 9.4E-48 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFE_0570 70e19d81a7565c00f412f520afe2a971 446 SUPERFAMILY SSF51905 4 437 9.71E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0770 abc6acaf676f724f798147d756d121e9 223 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 145 207 4.9E-13 T 12-10-2018 IPR006260 TonB/TolA, C-terminal AFE_0770 abc6acaf676f724f798147d756d121e9 223 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 145 214 1.1E-10 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 AFE_0770 abc6acaf676f724f798147d756d121e9 223 Gene3D G3DSA:3.30.1150.10 62 218 6.3E-16 T 12-10-2018 AFE_0770 abc6acaf676f724f798147d756d121e9 223 SUPERFAMILY SSF74653 105 208 2.35E-19 T 12-10-2018 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 SMART SM00926 215 269 3.5E-8 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 SUPERFAMILY SSF50692 705 774 8.14E-8 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 76 7.5E-19 T 12-10-2018 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 145 155 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Gene3D G3DSA:3.30.70.20 124 204 5.9E-7 T 12-10-2018 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 SMART SM00929 83 123 1.1E-14 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Gene3D G3DSA:2.40.40.20 697 779 1.3E-5 T 12-10-2018 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 216 264 4.8E-7 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 SUPERFAMILY SSF54292 2 114 7.03E-31 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Pfam PF00384 Molybdopterin oxidoreductase 272 627 1.5E-34 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 627 5.6E-195 T 12-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Gene3D G3DSA:3.10.20.740 1 123 1.5E-40 T 12-10-2018 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 SUPERFAMILY SSF54862 76 211 2.27E-34 T 12-10-2018 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Gene3D G3DSA:3.40.50.740 281 344 1.6E-19 T 12-10-2018 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Gene3D G3DSA:3.40.50.740 469 657 1.5E-20 T 12-10-2018 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Gene3D G3DSA:2.20.25.90 215 268 3.2E-12 T 12-10-2018 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Pfam PF01568 Molydopterin dinucleotide binding domain 704 761 1.1E-7 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Gene3D G3DSA:3.40.228.10 345 435 1.6E-19 T 12-10-2018 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 84 115 4.7E-14 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2624 071ca049bd5c35933d89c88f60c1b759 782 SUPERFAMILY SSF53706 213 652 2.22E-92 T 12-10-2018 AFE_0937 982170a5b52252bb2fec5ddc0f1275d3 422 SUPERFAMILY SSF56762 5 413 3.01E-90 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_0937 982170a5b52252bb2fec5ddc0f1275d3 422 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 404 413 - T 12-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AFE_0937 982170a5b52252bb2fec5ddc0f1275d3 422 Gene3D G3DSA:1.10.645.10 1 413 6.2E-103 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_0937 982170a5b52252bb2fec5ddc0f1275d3 422 Pfam PF00374 Nickel-dependent hydrogenase 289 413 3.3E-8 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AFE_0937 982170a5b52252bb2fec5ddc0f1275d3 422 Pfam PF00374 Nickel-dependent hydrogenase 34 120 3.2E-11 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AFE_1667 a93894a36c0e3961af0484ac29c790df 722 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 391 541 8.9E-13 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 AFE_1667 a93894a36c0e3961af0484ac29c790df 722 SUPERFAMILY SSF52922 567 718 4.4E-10 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_1667 a93894a36c0e3961af0484ac29c790df 722 Gene3D G3DSA:3.40.50.970 27 356 1.8E-36 T 12-10-2018 AFE_1667 a93894a36c0e3961af0484ac29c790df 722 Gene3D G3DSA:3.40.50.970 375 574 2.8E-36 T 12-10-2018 AFE_1667 a93894a36c0e3961af0484ac29c790df 722 SUPERFAMILY SSF52518 30 311 1.63E-30 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_1667 a93894a36c0e3961af0484ac29c790df 722 PIRSF PIRSF017245 3 719 2.4E-159 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 AFE_1667 a93894a36c0e3961af0484ac29c790df 722 Gene3D G3DSA:3.40.50.920 575 720 1.1E-7 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_1667 a93894a36c0e3961af0484ac29c790df 722 SUPERFAMILY SSF52518 365 561 1.06E-28 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_1667 a93894a36c0e3961af0484ac29c790df 722 SMART SM00861 373 561 3.2E-4 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_1667 a93894a36c0e3961af0484ac29c790df 722 Pfam PF09364 XFP N-terminal domain 87 235 1.2E-7 T 12-10-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal AFE_0457 a713f58c98479c3299ac1ef54d142ac1 330 Gene3D G3DSA:1.20.272.10 214 330 3.8E-29 T 12-10-2018 AFE_0457 a713f58c98479c3299ac1ef54d142ac1 330 Gene3D G3DSA:1.10.8.60 143 212 1.6E-18 T 12-10-2018 AFE_0457 a713f58c98479c3299ac1ef54d142ac1 330 Gene3D G3DSA:3.40.50.300 1 137 1.3E-33 T 12-10-2018 AFE_0457 a713f58c98479c3299ac1ef54d142ac1 330 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 329 2.2E-69 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 AFE_0457 a713f58c98479c3299ac1ef54d142ac1 330 SUPERFAMILY SSF48019 211 329 3.74E-24 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFE_0457 a713f58c98479c3299ac1ef54d142ac1 330 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 214 329 1.2E-10 T 12-10-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_0457 a713f58c98479c3299ac1ef54d142ac1 330 SUPERFAMILY SSF52540 1 209 6.9E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0457 a713f58c98479c3299ac1ef54d142ac1 330 Pfam PF06144 DNA polymerase III, delta subunit 22 188 2.9E-18 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 AFE_0094 c71d2242a95c6fbca5dc19f737284eeb 102 SUPERFAMILY SSF143120 27 92 1.05E-10 T 12-10-2018 IPR036165 YefM-like superfamily AFE_0094 c71d2242a95c6fbca5dc19f737284eeb 102 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 37 84 1.2E-8 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM AFE_0094 c71d2242a95c6fbca5dc19f737284eeb 102 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 37 72 9.4E-8 T 12-10-2018 AFE_0094 c71d2242a95c6fbca5dc19f737284eeb 102 Gene3D G3DSA:3.40.1620.10 32 69 1.4E-7 T 12-10-2018 AFE_0955 420aef3c21d4cb19e2df423b8bde81ce 542 PIRSF PIRSF006446 3 365 3.2E-109 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFE_0955 420aef3c21d4cb19e2df423b8bde81ce 542 PIRSF PIRSF006446 371 533 3.1E-35 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFE_0955 420aef3c21d4cb19e2df423b8bde81ce 542 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 10 512 1.1E-165 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFE_2672 5f79ffbe42df67952152a226355c9911 678 Gene3D G3DSA:3.40.50.620 5 379 9.7E-151 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2672 5f79ffbe42df67952152a226355c9911 678 Gene3D G3DSA:2.40.50.140 567 678 2.9E-32 T 12-10-2018 AFE_2672 5f79ffbe42df67952152a226355c9911 678 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 542 39.68 T 12-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFE_2672 5f79ffbe42df67952152a226355c9911 678 Pfam PF09334 tRNA synthetases class I (M) 5 392 1.1E-149 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_2672 5f79ffbe42df67952152a226355c9911 678 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_2672 5f79ffbe42df67952152a226355c9911 678 SUPERFAMILY SSF47323 386 542 2.43E-37 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_2672 5f79ffbe42df67952152a226355c9911 678 SUPERFAMILY SSF50249 573 677 6.37E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_2672 5f79ffbe42df67952152a226355c9911 678 SUPERFAMILY SSF57770 139 173 2.22E-12 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFE_2672 5f79ffbe42df67952152a226355c9911 678 Gene3D G3DSA:1.10.730.10 385 523 2.5E-32 T 12-10-2018 AFE_2672 5f79ffbe42df67952152a226355c9911 678 Gene3D G3DSA:2.20.28.20 139 173 9.7E-151 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFE_2672 5f79ffbe42df67952152a226355c9911 678 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 532 5.3E-168 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFE_2672 5f79ffbe42df67952152a226355c9911 678 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 1.3E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFE_2672 5f79ffbe42df67952152a226355c9911 678 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.3E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFE_2672 5f79ffbe42df67952152a226355c9911 678 PRINTS PR01041 Methionyl-tRNA synthetase signature 248 259 1.3E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFE_2672 5f79ffbe42df67952152a226355c9911 678 PRINTS PR01041 Methionyl-tRNA synthetase signature 287 302 1.3E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFE_2672 5f79ffbe42df67952152a226355c9911 678 PRINTS PR01041 Methionyl-tRNA synthetase signature 380 391 1.3E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFE_2672 5f79ffbe42df67952152a226355c9911 678 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.3E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFE_2672 5f79ffbe42df67952152a226355c9911 678 SUPERFAMILY SSF52374 2 382 3.29E-99 T 12-10-2018 AFE_2672 5f79ffbe42df67952152a226355c9911 678 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 566 678 2.2E-36 T 12-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFE_2672 5f79ffbe42df67952152a226355c9911 678 Pfam PF01588 Putative tRNA binding domain 583 675 9.0E-21 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 Gene3D G3DSA:3.40.50.1980 30 232 2.3E-126 T 12-10-2018 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 427 8.6E-157 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 19 428 40.067 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 PRINTS PR00083 Histidinol dehydrogenase signature 171 197 1.6E-86 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 PRINTS PR00083 Histidinol dehydrogenase signature 230 251 1.6E-86 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 PRINTS PR00083 Histidinol dehydrogenase signature 201 226 1.6E-86 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 PRINTS PR00083 Histidinol dehydrogenase signature 321 346 1.6E-86 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 PRINTS PR00083 Histidinol dehydrogenase signature 362 380 1.6E-86 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 PRINTS PR00083 Histidinol dehydrogenase signature 137 163 1.6E-86 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 1.6E-86 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 PRINTS PR00083 Histidinol dehydrogenase signature 252 271 1.6E-86 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 SUPERFAMILY SSF53720 29 427 2.16E-84 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 230 262 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 Pfam PF00815 Histidinol dehydrogenase 27 427 8.7E-164 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 Gene3D G3DSA:3.40.50.1980 234 350 2.3E-126 T 12-10-2018 AFE_3041 b28c4d7cb11a485b3e364c1e128578cc 433 PIRSF PIRSF000099 1 430 2.6E-155 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFE_0950 7dc2db546246661e43ce3542d5b3bd07 415 Gene3D G3DSA:3.50.50.60 2 100 2.1E-9 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0950 7dc2db546246661e43ce3542d5b3bd07 415 SUPERFAMILY SSF51905 5 413 7.41E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0950 7dc2db546246661e43ce3542d5b3bd07 415 Gene3D G3DSA:3.30.560.10 113 158 2.6E-14 T 12-10-2018 AFE_0950 7dc2db546246661e43ce3542d5b3bd07 415 Pfam PF00732 GMC oxidoreductase 5 226 1.1E-17 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFE_0950 7dc2db546246661e43ce3542d5b3bd07 415 Gene3D G3DSA:3.50.50.60 285 413 1.8E-7 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0950 7dc2db546246661e43ce3542d5b3bd07 415 Gene3D G3DSA:3.50.50.60 159 229 2.6E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0950 7dc2db546246661e43ce3542d5b3bd07 415 Pfam PF05199 GMC oxidoreductase 358 407 6.0E-7 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 AFE_2953 5be73d5c4749c607fe85443730a29cfe 195 Pfam PF02545 Maf-like protein 3 182 8.3E-51 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFE_2953 5be73d5c4749c607fe85443730a29cfe 195 Gene3D G3DSA:3.90.950.10 2 189 8.9E-62 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFE_2953 5be73d5c4749c607fe85443730a29cfe 195 PIRSF PIRSF006305 1 188 3.2E-46 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFE_2953 5be73d5c4749c607fe85443730a29cfe 195 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 181 1.5E-43 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFE_2953 5be73d5c4749c607fe85443730a29cfe 195 SUPERFAMILY SSF52972 2 181 5.04E-57 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFE_2953 5be73d5c4749c607fe85443730a29cfe 195 Hamap MF_00528 Septum formation protein Maf [maf]. 3 188 30.825 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 AFE_0370 4672fb733684292838d7ef8c7bd56d5e 237 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 3 230 42.689 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFE_0370 4672fb733684292838d7ef8c7bd56d5e 237 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 231 1.5E-62 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFE_0370 4672fb733684292838d7ef8c7bd56d5e 237 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 230 1.1E-63 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFE_0370 4672fb733684292838d7ef8c7bd56d5e 237 Gene3D G3DSA:3.90.550.10 1 235 1.3E-65 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0370 4672fb733684292838d7ef8c7bd56d5e 237 SUPERFAMILY SSF53448 4 230 6.53E-52 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0370 4672fb733684292838d7ef8c7bd56d5e 237 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 107 114 - T 12-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFE_0792 a14c41a8856181803800ad82a9db166d 253 Pfam PF00535 Glycosyl transferase family 2 11 169 7.4E-23 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFE_0792 a14c41a8856181803800ad82a9db166d 253 SUPERFAMILY SSF53448 11 250 1.62E-31 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0792 a14c41a8856181803800ad82a9db166d 253 Gene3D G3DSA:3.90.550.10 9 234 2.1E-22 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 509 518 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 Gene3D G3DSA:3.40.50.300 287 471 2.3E-55 T 12-10-2018 AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 323 336 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 Pfam PF00158 Sigma-54 interaction domain 303 466 3.2E-60 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 SMART SM00382 319 463 2.4E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 573 590 3.6E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 590 609 3.6E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 Gene3D G3DSA:1.10.10.60 562 607 1.6E-12 T 12-10-2018 AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 Gene3D G3DSA:1.10.8.60 472 550 1.7E-8 T 12-10-2018 AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 Gene3D G3DSA:3.30.450.40 1 177 1.5E-55 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 Pfam PF02954 Bacterial regulatory protein, Fis family 574 605 8.3E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 SUPERFAMILY SSF55781 30 176 5.89E-8 T 12-10-2018 AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 SUPERFAMILY SSF46689 509 605 5.38E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 SUPERFAMILY SSF52540 303 540 4.39E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1741 d1cc44ebb1f1bbb252338fac58d21837 609 Pfam PF01590 GAF domain 61 175 3.8E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 AFE_3101 0d7f5eeef01b14e67564aa9a267cb427 709 Gene3D G3DSA:1.10.486.10 376 531 8.0E-116 T 12-10-2018 AFE_3101 0d7f5eeef01b14e67564aa9a267cb427 709 Gene3D G3DSA:1.10.10.160 110 183 6.4E-89 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily AFE_3101 0d7f5eeef01b14e67564aa9a267cb427 709 Gene3D G3DSA:3.40.50.300 7 267 6.4E-89 T 12-10-2018 AFE_3101 0d7f5eeef01b14e67564aa9a267cb427 709 Gene3D G3DSA:3.40.50.300 275 629 8.0E-116 T 12-10-2018 AFE_3101 0d7f5eeef01b14e67564aa9a267cb427 709 SUPERFAMILY SSF52540 6 634 6.11E-165 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3101 0d7f5eeef01b14e67564aa9a267cb427 709 Pfam PF00580 UvrD/REP helicase N-terminal domain 7 265 3.8E-65 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFE_3101 0d7f5eeef01b14e67564aa9a267cb427 709 Pfam PF13361 UvrD-like helicase C-terminal domain 271 609 4.1E-69 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFE_1872 1e3a5d38044636b8cdfec67b48044197 255 SUPERFAMILY SSF54423 23 71 2.49E-5 T 12-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 AFE_1872 1e3a5d38044636b8cdfec67b48044197 255 Gene3D G3DSA:3.40.30.10 106 245 1.9E-29 T 12-10-2018 AFE_1872 1e3a5d38044636b8cdfec67b48044197 255 Pfam PF13098 Thioredoxin-like domain 106 227 4.9E-13 T 12-10-2018 IPR012336 Thioredoxin-like fold AFE_1872 1e3a5d38044636b8cdfec67b48044197 255 SUPERFAMILY SSF52833 98 233 3.49E-22 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1872 1e3a5d38044636b8cdfec67b48044197 255 Gene3D G3DSA:3.10.450.70 16 80 2.0E-9 T 12-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 AFE_1792 3f83bd894d2d5bb85ae4924fb45ff833 434 SUPERFAMILY SSF51905 139 304 3.64E-7 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1792 3f83bd894d2d5bb85ae4924fb45ff833 434 Gene3D G3DSA:3.50.50.100 1 418 3.0E-185 T 12-10-2018 AFE_1792 3f83bd894d2d5bb85ae4924fb45ff833 434 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 301 7.7E-23 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_1792 3f83bd894d2d5bb85ae4924fb45ff833 434 SUPERFAMILY SSF51905 3 342 1.2E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1920 da6440fb5867996e3a71b8407465af7f 107 SUPERFAMILY SSF82607 9 103 1.83E-33 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFE_1920 da6440fb5867996e3a71b8407465af7f 107 PIRSF PIRSF004555 1 107 9.4E-38 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFE_1920 da6440fb5867996e3a71b8407465af7f 107 Gene3D G3DSA:3.30.1310.10 1 107 7.5E-41 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFE_1920 da6440fb5867996e3a71b8407465af7f 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 103 4.4E-30 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFE_1920 da6440fb5867996e3a71b8407465af7f 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 3 97 21.695 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFE_1920 da6440fb5867996e3a71b8407465af7f 107 Pfam PF02575 YbaB/EbfC DNA-binding family 9 99 8.2E-34 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFE_0346 758cc5c95e94e9b0b12fb533120c4f59 145 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 6.3E-47 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0346 758cc5c95e94e9b0b12fb533120c4f59 145 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 12-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0346 758cc5c95e94e9b0b12fb533120c4f59 145 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 2.2E-30 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P AFE_0346 758cc5c95e94e9b0b12fb533120c4f59 145 Gene3D G3DSA:3.100.10.10 68 145 1.5E-13 T 12-10-2018 AFE_0346 758cc5c95e94e9b0b12fb533120c4f59 145 SUPERFAMILY SSF52080 4 144 7.33E-42 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily AFE_0346 758cc5c95e94e9b0b12fb533120c4f59 145 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 144 19.239 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 AFE_1869 0f7cca641a0878142b371dfeb40a2501 214 Gene3D G3DSA:3.40.50.300 50 165 1.9E-41 T 12-10-2018 AFE_1869 0f7cca641a0878142b371dfeb40a2501 214 SUPERFAMILY SSF52540 49 163 1.06E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1869 0f7cca641a0878142b371dfeb40a2501 214 PIRSF PIRSF037290 8 211 4.8E-55 T 12-10-2018 IPR017166 Uncharacterised conserved protein UCP037290 AFE_1869 0f7cca641a0878142b371dfeb40a2501 214 Pfam PF03846 Cell division inhibitor SulA 48 137 5.3E-10 T 12-10-2018 IPR004596 Cell division suppressor protein, SulA GO:0009432|GO:0051782 AFE_1446 ea2dcad8002f0d78c622210693f1400f 241 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 236 1.6E-102 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 AFE_1446 ea2dcad8002f0d78c622210693f1400f 241 Pfam PF00696 Amino acid kinase family 8 216 6.5E-30 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFE_1446 ea2dcad8002f0d78c622210693f1400f 241 SUPERFAMILY SSF53633 4 236 5.5E-74 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_1446 ea2dcad8002f0d78c622210693f1400f 241 PIRSF PIRSF005650 2 241 2.4E-96 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AFE_1446 ea2dcad8002f0d78c622210693f1400f 241 Gene3D G3DSA:3.40.1160.10 3 240 1.9E-79 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_1446 ea2dcad8002f0d78c622210693f1400f 241 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 46.418 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 AFE_1229 631f30794512a0ca1fc7944014279d1f 228 Gene3D G3DSA:3.20.20.450 3 225 9.5E-34 T 12-10-2018 IPR035919 EAL domain superfamily AFE_1229 631f30794512a0ca1fc7944014279d1f 228 Pfam PF00563 EAL domain 61 211 1.4E-25 T 12-10-2018 IPR001633 EAL domain AFE_1229 631f30794512a0ca1fc7944014279d1f 228 SUPERFAMILY SSF141868 14 212 1.44E-30 T 12-10-2018 IPR035919 EAL domain superfamily AFE_1229 631f30794512a0ca1fc7944014279d1f 228 SMART SM00052 4 219 3.0E-7 T 12-10-2018 IPR001633 EAL domain AFE_2973 3bade4f51481d98d8ed31de91209fb6b 278 Gene3D G3DSA:3.40.190.80 152 254 2.4E-35 T 12-10-2018 AFE_2973 3bade4f51481d98d8ed31de91209fb6b 278 Hamap MF_02095 3'(2'),5'-bisphosphate nucleotidase CysQ [cysQ]. 1 254 38.991 T 12-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 AFE_2973 3bade4f51481d98d8ed31de91209fb6b 278 Gene3D G3DSA:3.30.540.10 1 151 4.1E-50 T 12-10-2018 AFE_2973 3bade4f51481d98d8ed31de91209fb6b 278 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 78 91 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site AFE_2973 3bade4f51481d98d8ed31de91209fb6b 278 SUPERFAMILY SSF56655 2 251 2.36E-76 T 12-10-2018 AFE_2973 3bade4f51481d98d8ed31de91209fb6b 278 Pfam PF00459 Inositol monophosphatase family 5 243 2.3E-56 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_2973 3bade4f51481d98d8ed31de91209fb6b 278 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 2 252 1.8E-95 T 12-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 AFE_2429 60bf1200a88501344e93520259a44b4c 251 SUPERFAMILY SSF81342 13 204 1.33E-27 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFE_2429 60bf1200a88501344e93520259a44b4c 251 Gene3D G3DSA:1.20.950.20 3 188 3.7E-33 T 12-10-2018 AFE_2429 60bf1200a88501344e93520259a44b4c 251 Pfam PF01292 Prokaryotic cytochrome b561 14 199 3.3E-21 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFE_1270 ffabf4c2c1ada9fc76f16431a9ad7d01 211 Pfam PF04404 ERF superfamily 10 139 1.8E-23 T 12-10-2018 IPR007499 Essential recombination function protein AFE_0273 7f42cc2f6cadadddc20a3e4f83901ce4 377 Pfam PF02222 ATP-grasp domain 112 281 5.0E-51 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type AFE_0273 7f42cc2f6cadadddc20a3e4f83901ce4 377 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 7 358 6.7E-117 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 AFE_0273 7f42cc2f6cadadddc20a3e4f83901ce4 377 Gene3D G3DSA:3.30.470.20 182 372 2.5E-71 T 12-10-2018 AFE_0273 7f42cc2f6cadadddc20a3e4f83901ce4 377 SUPERFAMILY SSF51246 305 370 1.49E-15 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFE_0273 7f42cc2f6cadadddc20a3e4f83901ce4 377 SUPERFAMILY SSF52440 4 100 5.04E-27 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFE_0273 7f42cc2f6cadadddc20a3e4f83901ce4 377 SUPERFAMILY SSF56059 103 301 1.31E-58 T 12-10-2018 AFE_0273 7f42cc2f6cadadddc20a3e4f83901ce4 377 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 7 359 41.257 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 AFE_0273 7f42cc2f6cadadddc20a3e4f83901ce4 377 Gene3D G3DSA:3.40.50.20 1 107 1.9E-39 T 12-10-2018 AFE_0273 7f42cc2f6cadadddc20a3e4f83901ce4 377 Gene3D G3DSA:3.30.1490.20 108 180 1.2E-23 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFE_3268 32a0a6bece331f609a5122139e24d81b 97 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 8 51 1.2E-10 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM AFE_3268 32a0a6bece331f609a5122139e24d81b 97 Gene3D G3DSA:3.40.1620.10 5 41 1.8E-7 T 12-10-2018 AFE_3268 32a0a6bece331f609a5122139e24d81b 97 SUPERFAMILY SSF143120 6 58 3.14E-10 T 12-10-2018 IPR036165 YefM-like superfamily AFE_3268 32a0a6bece331f609a5122139e24d81b 97 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 10 50 6.3E-11 T 12-10-2018 AFE_0251 8cb7ac2d12f5406c667f07d737237367 201 Pfam PF00929 Exonuclease 14 187 9.4E-29 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFE_0251 8cb7ac2d12f5406c667f07d737237367 201 Hamap MF_00157 Ribonuclease T [rnt]. 1 201 87.467 T 12-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 AFE_0251 8cb7ac2d12f5406c667f07d737237367 201 Gene3D G3DSA:3.30.420.10 3 199 3.5E-50 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_0251 8cb7ac2d12f5406c667f07d737237367 201 SUPERFAMILY SSF53098 5 194 3.99E-51 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_0251 8cb7ac2d12f5406c667f07d737237367 201 TIGRFAM TIGR01298 RNaseT: ribonuclease T 5 195 9.3E-84 T 12-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 AFE_0251 8cb7ac2d12f5406c667f07d737237367 201 SMART SM00479 12 196 1.1E-24 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFE_1935 b3cb1c55424951b41aa72cee4f88fcc3 203 Gene3D G3DSA:1.25.40.10 26 201 3.6E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1935 b3cb1c55424951b41aa72cee4f88fcc3 203 PIRSF PIRSF006170 3 203 4.6E-46 T 12-10-2018 IPR026039 Uncharacterised protein family UPF0070 AFE_1935 b3cb1c55424951b41aa72cee4f88fcc3 203 Pfam PF09976 Tetratricopeptide repeat-like domain 11 200 4.7E-42 T 12-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 AFE_1990 6f07698bd037860515ee2e26618c4cf8 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 57 1.2E-19 T 12-10-2018 AFE_1990 6f07698bd037860515ee2e26618c4cf8 161 SMART SM00344 10 120 4.2E-41 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFE_1990 6f07698bd037860515ee2e26618c4cf8 161 SUPERFAMILY SSF54909 71 160 1.52E-20 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFE_1990 6f07698bd037860515ee2e26618c4cf8 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 3.7E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFE_1990 6f07698bd037860515ee2e26618c4cf8 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 3.7E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFE_1990 6f07698bd037860515ee2e26618c4cf8 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 3.7E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AFE_1990 6f07698bd037860515ee2e26618c4cf8 161 Gene3D G3DSA:1.10.10.10 1 63 5.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1990 6f07698bd037860515ee2e26618c4cf8 161 Pfam PF01037 Lrp/AsnC ligand binding domain 77 150 7.0E-24 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFE_1990 6f07698bd037860515ee2e26618c4cf8 161 Gene3D G3DSA:3.30.70.920 64 148 1.3E-27 T 12-10-2018 AFE_1990 6f07698bd037860515ee2e26618c4cf8 161 SUPERFAMILY SSF46785 9 97 1.9E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1515 bd48eb91395a477aca7d2c51d2219302 138 SUPERFAMILY SSF53146 1 119 1.22E-33 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AFE_1515 bd48eb91395a477aca7d2c51d2219302 138 Gene3D G3DSA:3.30.420.130 1 119 2.6E-33 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AFE_1515 bd48eb91395a477aca7d2c51d2219302 138 TIGRFAM TIGR02663 nifX: nitrogen fixation protein NifX 1 119 2.2E-55 T 12-10-2018 IPR013480 Nitrogen fixation protein NifX GO:0009399|GO:0051188|GO:0051540 AFE_1515 bd48eb91395a477aca7d2c51d2219302 138 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 11 104 3.8E-18 T 12-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis AFE_3236 9bac25865233acc1a6c6bc1ae11e677d 309 SMART SM00382 30 215 8.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_3236 9bac25865233acc1a6c6bc1ae11e677d 309 Pfam PF00005 ABC transporter 21 164 9.4E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_3236 9bac25865233acc1a6c6bc1ae11e677d 309 Gene3D G3DSA:3.40.50.300 2 229 1.9E-73 T 12-10-2018 AFE_3236 9bac25865233acc1a6c6bc1ae11e677d 309 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_3236 9bac25865233acc1a6c6bc1ae11e677d 309 SUPERFAMILY SSF52540 5 225 1.3E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 SUPERFAMILY SSF52317 1 186 8.07E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 5.4E-86 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 Gene3D G3DSA:3.40.50.880 1 187 8.1E-62 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 2.5E-13 T 12-10-2018 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 2.5E-13 T 12-10-2018 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 2.5E-13 T 12-10-2018 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 Pfam PF00117 Glutamine amidotransferase class-I 4 185 2.6E-55 T 12-10-2018 IPR017926 Glutamine amidotransferase AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.1E-36 T 12-10-2018 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00097 Anthranilate synthase component II signature 164 177 1.1E-36 T 12-10-2018 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.1E-36 T 12-10-2018 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.1E-36 T 12-10-2018 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.1E-36 T 12-10-2018 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.1E-36 T 12-10-2018 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 3.2E-5 T 12-10-2018 AFE_3244 8e85a662f6e9ac77506bdd981e90231d 190 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 3.2E-5 T 12-10-2018 AFE_2220 945d86b7fa38ca984d421e6ea7d15ba4 782 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 422 6.1E-162 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 AFE_2220 945d86b7fa38ca984d421e6ea7d15ba4 782 Hamap MF_00970 Ribonuclease E [rne]. 1 766 28.733 T 12-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 AFE_2220 945d86b7fa38ca984d421e6ea7d15ba4 782 Gene3D G3DSA:2.40.50.140 31 123 1.9E-33 T 12-10-2018 AFE_2220 945d86b7fa38ca984d421e6ea7d15ba4 782 SUPERFAMILY SSF50249 40 123 8.25E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_2220 945d86b7fa38ca984d421e6ea7d15ba4 782 Gene3D G3DSA:3.40.1260.20 398 496 5.2E-31 T 12-10-2018 AFE_2220 945d86b7fa38ca984d421e6ea7d15ba4 782 Pfam PF10150 Ribonuclease E/G family 119 388 2.9E-96 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 AFE_2220 945d86b7fa38ca984d421e6ea7d15ba4 782 Pfam PF00575 S1 RNA binding domain 36 116 1.4E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_2220 945d86b7fa38ca984d421e6ea7d15ba4 782 SMART SM00316 37 117 1.7E-10 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00369 Flavodoxin signature 59 72 6.7E-12 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00369 Flavodoxin signature 107 118 6.7E-12 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00369 Flavodoxin signature 139 149 6.7E-12 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00369 Flavodoxin signature 163 182 6.7E-12 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 Gene3D G3DSA:3.40.50.80 436 588 1.9E-52 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 Gene3D G3DSA:3.40.50.360 49 207 2.9E-41 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 Gene3D G3DSA:2.40.30.10 223 430 4.7E-66 T 12-10-2018 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PIRSF PIRSF000207 2 588 1.5E-204 T 12-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 Pfam PF00667 FAD binding domain 221 415 1.6E-25 T 12-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 Pfam PF00258 Flavodoxin 60 184 1.9E-24 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 SUPERFAMILY SSF52218 57 199 2.39E-41 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 Pfam PF00175 Oxidoreductase NAD-binding domain 448 553 7.8E-18 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 472 481 1.1E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 539 547 1.1E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 485 496 1.1E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 410 419 1.1E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 258 268 1.1E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 516 532 1.1E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 447 466 1.1E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 377 384 1.1E-25 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 SUPERFAMILY SSF63380 216 436 6.81E-58 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 SUPERFAMILY SSF52343 435 588 8.38E-48 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFE_3121 27bc27c83d9bf48778fee8b4f56eedc5 588 Gene3D G3DSA:1.20.990.10 268 375 4.7E-66 T 12-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 AFE_3073 0d53f133f690c244629e5e6618e67f4d 344 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 12-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFE_3073 0d53f133f690c244629e5e6618e67f4d 344 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 140 7.4E-34 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFE_3073 0d53f133f690c244629e5e6618e67f4d 344 SMART SM00859 3 141 8.8E-56 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFE_3073 0d53f133f690c244629e5e6618e67f4d 344 Gene3D G3DSA:3.40.50.720 3 329 1.4E-127 T 12-10-2018 AFE_3073 0d53f133f690c244629e5e6618e67f4d 344 SUPERFAMILY SSF55347 149 312 4.58E-51 T 12-10-2018 AFE_3073 0d53f133f690c244629e5e6618e67f4d 344 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 344 3.2E-126 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFE_3073 0d53f133f690c244629e5e6618e67f4d 344 Gene3D G3DSA:3.30.360.10 147 312 1.4E-127 T 12-10-2018 AFE_3073 0d53f133f690c244629e5e6618e67f4d 344 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 338 42.02 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFE_3073 0d53f133f690c244629e5e6618e67f4d 344 SUPERFAMILY SSF51735 2 174 1.01E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3073 0d53f133f690c244629e5e6618e67f4d 344 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 158 315 6.1E-17 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFE_1383 a24db9864efc23bae202e5d724831084 102 Gene3D G3DSA:1.10.260.40 13 76 2.7E-21 T 12-10-2018 AFE_1383 a24db9864efc23bae202e5d724831084 102 SMART SM00530 27 83 0.0044 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_1383 a24db9864efc23bae202e5d724831084 102 Pfam PF13744 Helix-turn-helix domain 6 84 2.1E-28 T 12-10-2018 IPR039554 HigA2-like, helix-turn-helix domain AFE_1383 a24db9864efc23bae202e5d724831084 102 SUPERFAMILY SSF47413 13 90 3.06E-21 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_0600 81dfe98aa411f5c41376c167f1c93581 448 Pfam PF01523 Putative modulator of DNA gyrase 33 325 8.0E-65 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AFE_0600 81dfe98aa411f5c41376c167f1c93581 448 Gene3D G3DSA:3.30.2290.10 2 234 1.9E-91 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal AFE_0600 81dfe98aa411f5c41376c167f1c93581 448 SUPERFAMILY SSF111283 14 447 7.85E-132 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 Gene3D G3DSA:3.10.50.40 285 386 3.5E-56 T 12-10-2018 AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 Pfam PF09312 SurA N-terminal domain 30 147 1.1E-31 T 12-10-2018 IPR015391 SurA N-terminal AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 Gene3D G3DSA:1.10.4030.30 27 181 6.7E-42 T 12-10-2018 AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 322 343 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 SUPERFAMILY SSF109998 30 205 6.67E-39 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 SUPERFAMILY SSF54534 180 279 4.97E-23 T 12-10-2018 AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 Pfam PF00639 PPIC-type PPIASE domain 301 378 8.0E-17 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 Pfam PF00639 PPIC-type PPIASE domain 183 274 5.7E-15 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 SUPERFAMILY SSF54534 285 381 3.73E-23 T 12-10-2018 AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 Gene3D G3DSA:3.10.50.40 182 388 3.5E-56 T 12-10-2018 AFE_3035 ece06dbebade3d9982fd53d53ce44ec9 436 Hamap MF_01183 Chaperone SurA [surA]. 6 429 26.036 T 12-10-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0043165|GO:0050821|GO:0051082|GO:0060274 AFE_1658 7f2608826ba682098d6c361096dc5279 222 SUPERFAMILY SSF51206 3 140 2.62E-30 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like AFE_1658 7f2608826ba682098d6c361096dc5279 222 Gene3D G3DSA:2.60.120.10 1 141 3.7E-37 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_1658 7f2608826ba682098d6c361096dc5279 222 Pfam PF00027 Cyclic nucleotide-binding domain 31 115 2.4E-16 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFE_1658 7f2608826ba682098d6c361096dc5279 222 SMART SM00100 9 127 3.1E-24 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain AFE_1658 7f2608826ba682098d6c361096dc5279 222 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 168 184 1.1E-5 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_1658 7f2608826ba682098d6c361096dc5279 222 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 184 199 1.1E-5 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_1658 7f2608826ba682098d6c361096dc5279 222 SUPERFAMILY SSF46785 144 219 7.85E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1658 7f2608826ba682098d6c361096dc5279 222 Pfam PF13545 Crp-like helix-turn-helix domain 147 216 1.8E-14 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_1658 7f2608826ba682098d6c361096dc5279 222 SMART SM00419 162 210 1.1E-12 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFE_1658 7f2608826ba682098d6c361096dc5279 222 Gene3D G3DSA:1.10.10.10 142 218 9.9E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_3123 c88806e2447680422101a27654aa7fc9 245 Gene3D G3DSA:3.40.50.620 8 232 1.2E-66 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_3123 c88806e2447680422101a27654aa7fc9 245 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 30 223 8.5E-78 T 12-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 AFE_3123 c88806e2447680422101a27654aa7fc9 245 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 25 224 4.8E-52 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 AFE_3123 c88806e2447680422101a27654aa7fc9 245 PIRSF PIRSF000857 14 230 2.9E-76 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 AFE_3123 c88806e2447680422101a27654aa7fc9 245 SUPERFAMILY SSF52402 22 187 3.95E-44 T 12-10-2018 AFE_3123 c88806e2447680422101a27654aa7fc9 245 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 26 199 5.5E-41 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 Gene3D G3DSA:3.40.50.1000 480 744 3.2E-88 T 12-10-2018 IPR023214 HAD superfamily AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00942 Copper-transporting ATPase 1 signature 3 28 1.3E-10 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00942 Copper-transporting ATPase 1 signature 159 180 1.3E-10 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00942 Copper-transporting ATPase 1 signature 213 238 1.3E-10 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00942 Copper-transporting ATPase 1 signature 29 52 1.3E-10 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 266 802 1.5E-115 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 Pfam PF00403 Heavy-metal-associated domain 8 66 1.1E-15 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 Pfam PF00403 Heavy-metal-associated domain 76 133 6.8E-14 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 Gene3D G3DSA:3.40.1110.10 510 625 3.2E-88 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00943 Copper-transporting ATPase signature 86 100 1.3E-16 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00943 Copper-transporting ATPase signature 215 234 1.3E-16 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00943 Copper-transporting ATPase signature 420 434 1.3E-16 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00943 Copper-transporting ATPase signature 267 286 1.3E-16 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00943 Copper-transporting ATPase signature 482 497 1.3E-16 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00943 Copper-transporting ATPase signature 670 687 1.3E-16 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00943 Copper-transporting ATPase signature 766 780 1.3E-16 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 501 507 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 212 802 1.2E-175 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 230 801 8.4E-182 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 SUPERFAMILY SSF81653 301 397 1.44E-27 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 SUPERFAMILY SSF56784 497 799 4.12E-53 T 12-10-2018 IPR036412 HAD-like superfamily AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 Gene3D G3DSA:2.70.150.20 290 402 5.9E-39 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 Pfam PF00702 haloacid dehalogenase-like hydrolase 495 707 2.7E-40 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 Gene3D G3DSA:3.30.70.100 3 71 1.3E-21 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 Pfam PF00122 E1-E2 ATPase 298 478 1.0E-54 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 SUPERFAMILY SSF81665 264 767 1.03E-12 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 SUPERFAMILY SSF55008 4 71 1.05E-19 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 270 777 1.2E-87 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 SUPERFAMILY SSF55008 71 139 1.15E-20 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 640 650 1.1E-28 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 499 513 1.1E-28 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 716 728 1.1E-28 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 618 629 1.1E-28 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 347 361 1.1E-28 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 693 712 1.1E-28 T 12-10-2018 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 ProSitePatterns PS01047 Heavy-metal-associated domain. 76 105 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 4 66 4.4E-11 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 73 134 1.8E-8 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 AFE_2021 eeb70dca5330cfbce5d43a51391c1782 811 Gene3D G3DSA:3.30.70.100 72 138 1.0E-20 T 12-10-2018 AFE_1807 3bc78c71459a8b85b919530b10aadf58 319 Pfam PF00294 pfkB family carbohydrate kinase 29 298 4.7E-40 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFE_1807 3bc78c71459a8b85b919530b10aadf58 319 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 11 310 4.3E-87 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 AFE_1807 3bc78c71459a8b85b919530b10aadf58 319 Gene3D G3DSA:3.40.1190.20 10 317 3.5E-86 T 12-10-2018 IPR029056 Ribokinase-like AFE_1807 3bc78c71459a8b85b919530b10aadf58 319 PIRSF PIRSF000535 8 316 3.3E-76 T 12-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 AFE_1807 3bc78c71459a8b85b919530b10aadf58 319 SUPERFAMILY SSF53613 12 299 5.61E-59 T 12-10-2018 IPR029056 Ribokinase-like AFE_1807 3bc78c71459a8b85b919530b10aadf58 319 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 255 268 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFE_0174 957c9ccffff9260c89e90c3ad600d5d3 253 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 253 3.6E-83 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 AFE_0174 957c9ccffff9260c89e90c3ad600d5d3 253 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 188 203 - T 12-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 AFE_0174 957c9ccffff9260c89e90c3ad600d5d3 253 Gene3D G3DSA:3.60.10.10 1 253 9.4E-86 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFE_0174 957c9ccffff9260c89e90c3ad600d5d3 253 SUPERFAMILY SSF56219 1 253 2.62E-76 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFE_0174 957c9ccffff9260c89e90c3ad600d5d3 253 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 252 4.7E-76 T 12-10-2018 AFE_0174 957c9ccffff9260c89e90c3ad600d5d3 253 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 245 2.3E-21 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFE_3126 9f1681115ab7db159177706baed63cfc 273 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 90 123 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFE_3126 9f1681115ab7db159177706baed63cfc 273 SUPERFAMILY SSF53790 9 250 1.26E-72 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFE_3126 9f1681115ab7db159177706baed63cfc 273 Gene3D G3DSA:3.40.1010.10 8 125 7.2E-42 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFE_3126 9f1681115ab7db159177706baed63cfc 273 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 221 1.7E-46 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFE_3126 9f1681115ab7db159177706baed63cfc 273 Gene3D G3DSA:3.30.950.10 126 257 5.7E-41 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFE_3126 9f1681115ab7db159177706baed63cfc 273 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 15 29 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFE_3126 9f1681115ab7db159177706baed63cfc 273 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 10 245 4.0E-89 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFE_2173 f471506da273216e925d7bb52aa10026 176 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFE_2173 f471506da273216e925d7bb52aa10026 176 SUPERFAMILY SSF55811 3 149 1.04E-28 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFE_2173 f471506da273216e925d7bb52aa10026 176 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 3 154 34.727 T 12-10-2018 IPR022927 RNA pyrophosphohydrolase RppH AFE_2173 f471506da273216e925d7bb52aa10026 176 PRINTS PR00502 NUDIX hydrolase family signature 35 49 6.0E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFE_2173 f471506da273216e925d7bb52aa10026 176 PRINTS PR00502 NUDIX hydrolase family signature 49 64 6.0E-6 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFE_2173 f471506da273216e925d7bb52aa10026 176 Gene3D G3DSA:3.90.79.10 2 156 9.3E-41 T 12-10-2018 AFE_2173 f471506da273216e925d7bb52aa10026 176 Pfam PF00293 NUDIX domain 9 134 1.1E-23 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFE_2124 ef310e64c2287f0f5a42682be3cd54ee 643 SUPERFAMILY SSF48239 316 636 6.28E-94 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AFE_2124 ef310e64c2287f0f5a42682be3cd54ee 643 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 23 310 2.7E-113 T 12-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 AFE_2124 ef310e64c2287f0f5a42682be3cd54ee 643 SUPERFAMILY SSF48239 47 315 8.37E-72 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AFE_2124 ef310e64c2287f0f5a42682be3cd54ee 643 Gene3D G3DSA:1.50.10.20 44 319 1.6E-216 T 12-10-2018 AFE_2124 ef310e64c2287f0f5a42682be3cd54ee 643 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 320 636 1.3E-136 T 12-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 AFE_2124 ef310e64c2287f0f5a42682be3cd54ee 643 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 23 636 8.0E-185 T 12-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 AFE_2124 ef310e64c2287f0f5a42682be3cd54ee 643 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 21 637 1.2E-239 T 12-10-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 AFE_2124 ef310e64c2287f0f5a42682be3cd54ee 643 Gene3D G3DSA:1.50.10.20 26 634 1.6E-216 T 12-10-2018 AFE_1369 259204560c15631740eae4ee04d4eb79 259 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 109 238 9.719 T 12-10-2018 IPR022907 VapC family GO:0004540 AFE_1369 259204560c15631740eae4ee04d4eb79 259 Pfam PF01850 PIN domain 110 224 1.1E-12 T 12-10-2018 IPR002716 PIN domain AFE_1369 259204560c15631740eae4ee04d4eb79 259 Gene3D G3DSA:3.40.50.1010 109 241 5.5E-8 T 12-10-2018 AFE_1369 259204560c15631740eae4ee04d4eb79 259 SUPERFAMILY SSF88723 108 241 4.49E-17 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_0587 cd3d5c5a0b8d73786c0211ec47bf708a 335 Gene3D G3DSA:1.20.58.1130 7 227 2.6E-35 T 12-10-2018 AFE_0587 cd3d5c5a0b8d73786c0211ec47bf708a 335 Gene3D G3DSA:1.20.1420.30 33 286 2.6E-35 T 12-10-2018 AFE_0587 cd3d5c5a0b8d73786c0211ec47bf708a 335 Pfam PF01699 Sodium/calcium exchanger protein 3 161 1.3E-15 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AFE_0587 cd3d5c5a0b8d73786c0211ec47bf708a 335 Pfam PF01699 Sodium/calcium exchanger protein 197 282 2.8E-10 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AFE_1042 9817b47fa4c000682d0c824917fb9943 209 Pfam PF09618 CRISPR-associated protein (Cas_Csy4) 28 199 4.0E-14 T 12-10-2018 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 AFE_1042 9817b47fa4c000682d0c824917fb9943 209 Gene3D G3DSA:1.10.8.890 141 157 4.8E-11 T 12-10-2018 AFE_1042 9817b47fa4c000682d0c824917fb9943 209 Gene3D G3DSA:3.30.70.2540 49 200 4.8E-11 T 12-10-2018 AFE_2970 b2fea02c6fb87708b2e9c8bd4880d4f1 293 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 2 293 1.9E-145 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFE_2970 b2fea02c6fb87708b2e9c8bd4880d4f1 293 PIRSF PIRSF002936 1 293 2.7E-141 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFE_2970 b2fea02c6fb87708b2e9c8bd4880d4f1 293 SUPERFAMILY SSF52402 3 200 7.5E-68 T 12-10-2018 AFE_2970 b2fea02c6fb87708b2e9c8bd4880d4f1 293 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 21 248 2.8E-58 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 AFE_2970 b2fea02c6fb87708b2e9c8bd4880d4f1 293 Gene3D G3DSA:3.40.50.620 1 203 1.9E-61 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 Gene3D G3DSA:2.40.30.10 241 332 7.6E-23 T 12-10-2018 AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 Pfam PF00009 Elongation factor Tu GTP binding domain 20 226 1.7E-36 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 SUPERFAMILY SSF50465 338 437 8.15E-32 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 PRINTS PR00315 GTP-binding elongation factor signature 81 89 1.4E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 PRINTS PR00315 GTP-binding elongation factor signature 163 172 1.4E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 PRINTS PR00315 GTP-binding elongation factor signature 21 34 1.4E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 PRINTS PR00315 GTP-binding elongation factor signature 101 111 1.4E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 PRINTS PR00315 GTP-binding elongation factor signature 117 128 1.4E-13 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 SUPERFAMILY SSF50447 242 333 1.81E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 SUPERFAMILY SSF52540 17 255 2.2E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 20 437 1.4E-162 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 74 89 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 Gene3D G3DSA:3.40.50.300 3 240 6.9E-62 T 12-10-2018 AFE_3125 824c6c92b4a7940a1d422dbc9a9ab928 450 Gene3D G3DSA:2.40.30.10 335 438 8.6E-35 T 12-10-2018 AFE_3103 eda903721ca389374e2079e05b9f82a3 222 Pfam PF00156 Phosphoribosyl transferase domain 8 194 2.4E-30 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFE_3103 eda903721ca389374e2079e05b9f82a3 222 Gene3D G3DSA:3.40.50.2020 8 207 3.8E-63 T 12-10-2018 AFE_3103 eda903721ca389374e2079e05b9f82a3 222 Gene3D G3DSA:3.30.1310.20 58 119 3.8E-63 T 12-10-2018 AFE_3103 eda903721ca389374e2079e05b9f82a3 222 SUPERFAMILY SSF53271 8 212 1.41E-43 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFE_2367 ea583ba681d5b00df4bf3e4550ad5ed6 360 Gene3D G3DSA:1.10.287.470 98 167 3.6E-66 T 12-10-2018 AFE_2367 ea583ba681d5b00df4bf3e4550ad5ed6 360 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 53 263 1.3E-15 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_2367 ea583ba681d5b00df4bf3e4550ad5ed6 360 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 353 5.6E-69 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_2367 ea583ba681d5b00df4bf3e4550ad5ed6 360 SUPERFAMILY SSF111369 53 236 5.89E-30 T 12-10-2018 AFE_2367 ea583ba681d5b00df4bf3e4550ad5ed6 360 Gene3D G3DSA:2.40.50.100 64 204 3.6E-66 T 12-10-2018 AFE_2367 ea583ba681d5b00df4bf3e4550ad5ed6 360 Gene3D G3DSA:2.40.30.170 52 280 3.6E-66 T 12-10-2018 AFE_2367 ea583ba681d5b00df4bf3e4550ad5ed6 360 Gene3D G3DSA:2.40.420.20 47 339 3.6E-66 T 12-10-2018 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 Gene3D G3DSA:1.25.40.10 10 313 3.6E-66 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 Gene3D G3DSA:1.25.40.10 316 447 1.0E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SMART SM00028 250 283 0.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SMART SM00028 46 79 73.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SMART SM00028 319 352 3.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SMART SM00028 284 317 28.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SMART SM00028 216 249 8.7 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SMART SM00028 182 215 0.0042 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SMART SM00028 148 181 1.6E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SMART SM00028 80 113 0.076 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SMART SM00028 114 147 0.0018 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SMART SM00028 12 45 130.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SUPERFAMILY SSF48452 17 146 1.44E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 Pfam PF13432 Tetratricopeptide repeat 256 314 1.9E-5 T 12-10-2018 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 Pfam PF13432 Tetratricopeptide repeat 16 78 5.7E-6 T 12-10-2018 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SUPERFAMILY SSF48452 110 360 3.22E-38 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 Gene3D G3DSA:3.40.50.300 450 695 7.5E-61 T 12-10-2018 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 Pfam PF13424 Tetratricopeptide repeat 114 178 2.1E-8 T 12-10-2018 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 Pfam PF13374 Tetratricopeptide repeat 84 109 0.015 T 12-10-2018 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 Pfam PF13469 Sulfotransferase family 460 642 9.0E-42 T 12-10-2018 AFE_1211 660dc54e60e5e76355f96f0f0ac6e46f 695 SUPERFAMILY SSF52540 460 678 5.65E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2528 88d531baf23e06467709814afc5b9082 250 Gene3D G3DSA:3.40.50.880 7 243 6.4E-68 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_2528 88d531baf23e06467709814afc5b9082 250 SUPERFAMILY SSF52317 29 238 7.84E-39 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_2528 88d531baf23e06467709814afc5b9082 250 Pfam PF07722 Peptidase C26 23 215 8.5E-58 T 12-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 Gene3D G3DSA:3.40.50.970 2 325 6.6E-133 T 12-10-2018 AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 Pfam PF02780 Transketolase, C-terminal domain 554 656 1.4E-11 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 662 1.2E-295 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 330 5.3E-162 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 SUPERFAMILY SSF52518 348 525 3.76E-65 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 ProSitePatterns PS00801 Transketolase signature 1. 11 31 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 SUPERFAMILY SSF52922 535 662 5.5E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 Gene3D G3DSA:3.40.50.920 538 661 4.9E-42 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 SUPERFAMILY SSF52518 5 327 1.68E-120 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 Pfam PF02779 Transketolase, pyrimidine binding domain 353 524 2.1E-45 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 SMART SM00861 354 525 6.5E-66 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_3252 8eaf128bfd42a58f009b6575a4ef7309 663 Gene3D G3DSA:3.40.50.970 328 537 3.3E-78 T 12-10-2018 AFE_0866 301103797f74d2b65fd37aa1bc7c16ad 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.2E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0866 301103797f74d2b65fd37aa1bc7c16ad 307 SUPERFAMILY SSF53850 90 293 2.02E-33 T 12-10-2018 AFE_0866 301103797f74d2b65fd37aa1bc7c16ad 307 Gene3D G3DSA:3.40.190.10 91 289 1.4E-35 T 12-10-2018 AFE_0866 301103797f74d2b65fd37aa1bc7c16ad 307 Pfam PF03466 LysR substrate binding domain 89 292 1.9E-36 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_0866 301103797f74d2b65fd37aa1bc7c16ad 307 Gene3D G3DSA:1.10.10.10 1 89 1.6E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0866 301103797f74d2b65fd37aa1bc7c16ad 307 Gene3D G3DSA:3.40.190.10 166 267 1.4E-35 T 12-10-2018 AFE_0866 301103797f74d2b65fd37aa1bc7c16ad 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.8E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0866 301103797f74d2b65fd37aa1bc7c16ad 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.8E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0866 301103797f74d2b65fd37aa1bc7c16ad 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.8E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0866 301103797f74d2b65fd37aa1bc7c16ad 307 SUPERFAMILY SSF46785 1 110 4.58E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 1.6E-32 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 357 373 1.6E-32 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 286 295 1.6E-32 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 1.6E-32 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 468 482 1.6E-32 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 646 49.393 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 SMART SM00436 104 192 5.7E-32 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 Pfam PF01131 DNA topoisomerase 128 542 7.5E-105 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 Gene3D G3DSA:1.10.290.10 252 372 2.7E-114 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 SMART SM00437 244 507 1.9E-86 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 Gene3D G3DSA:3.40.50.140 1 134 2.8E-42 T 12-10-2018 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 Gene3D G3DSA:1.10.460.10 135 542 2.7E-114 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 Pfam PF01751 Toprim domain 4 111 3.8E-22 T 12-10-2018 IPR006171 TOPRIM domain AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 SMART SM00493 2 103 2.7E-18 T 12-10-2018 IPR006171 TOPRIM domain AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 4 556 5.8E-141 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 Gene3D G3DSA:2.70.20.10 184 452 2.7E-114 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AFE_1013 85df59d5c0bc45861a2909cd6118c3d1 705 SUPERFAMILY SSF56712 2 628 3.27E-152 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AFE_0638 1f94c2c43826b594713f88a034b65073 158 SUPERFAMILY SSF46557 4 79 1.01E-27 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 AFE_0638 1f94c2c43826b594713f88a034b65073 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 2.3E-27 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AFE_0638 1f94c2c43826b594713f88a034b65073 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 18 49 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AFE_0638 1f94c2c43826b594713f88a034b65073 158 Gene3D G3DSA:3.10.50.30 80 158 3.2E-29 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 AFE_0638 1f94c2c43826b594713f88a034b65073 158 SUPERFAMILY SSF54534 84 157 3.14E-22 T 12-10-2018 AFE_0638 1f94c2c43826b594713f88a034b65073 158 Gene3D G3DSA:1.10.287.180 2 76 1.4E-29 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 AFE_0638 1f94c2c43826b594713f88a034b65073 158 Pfam PF03449 Transcription elongation factor, N-terminal 5 75 1.6E-30 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AFE_0638 1f94c2c43826b594713f88a034b65073 158 PIRSF PIRSF006092 1 158 4.9E-52 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 AFE_0638 1f94c2c43826b594713f88a034b65073 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AFE_0638 1f94c2c43826b594713f88a034b65073 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 6 155 3.6E-56 T 12-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 AFE_0638 1f94c2c43826b594713f88a034b65073 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 3 156 32.468 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 PRINTS PR00415 Aconitase family signature 90 98 5.8E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 PRINTS PR00415 Aconitase family signature 110 123 5.8E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 PRINTS PR00415 Aconitase family signature 200 213 5.8E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 PRINTS PR00415 Aconitase family signature 186 199 5.8E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 PRINTS PR00415 Aconitase family signature 349 362 5.8E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 PRINTS PR00415 Aconitase family signature 124 139 5.8E-24 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 5 641 3.1E-273 T 12-10-2018 IPR006250 Aconitase, putative AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 SUPERFAMILY SSF52016 438 640 4.71E-49 T 12-10-2018 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 ProSitePatterns PS01244 Aconitase family signature 2. 349 362 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 SUPERFAMILY SSF53732 1 418 1.12E-147 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 Pfam PF00330 Aconitase family (aconitate hydratase) 7 407 6.1E-110 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 ProSitePatterns PS00450 Aconitase family signature 1. 289 305 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 Gene3D G3DSA:3.30.499.20 4 267 2.0E-83 T 12-10-2018 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 Pfam PF00694 Aconitase C-terminal domain 523 575 9.5E-22 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 Gene3D G3DSA:3.30.499.10 270 415 7.6E-48 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 AFE_0423 c7c1a4376b836d0b436e625efc5920e1 645 Gene3D G3DSA:3.20.19.10 464 645 1.6E-44 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 SUPERFAMILY SSF48168 144 355 7.32E-57 T 12-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 283 910 1.4E-210 T 12-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 PRINTS PR01183 Ribonucleotide reductase large chain signature 567 578 1.5E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 PRINTS PR01183 Ribonucleotide reductase large chain signature 687 710 1.5E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 PRINTS PR01183 Ribonucleotide reductase large chain signature 432 451 1.5E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 PRINTS PR01183 Ribonucleotide reductase large chain signature 621 644 1.5E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 PRINTS PR01183 Ribonucleotide reductase large chain signature 659 681 1.5E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 PRINTS PR01183 Ribonucleotide reductase large chain signature 762 789 1.5E-45 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 Pfam PF02867 Ribonucleotide reductase, barrel domain 357 907 1.9E-178 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 280 351 1.9E-19 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 752 773 - T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 Pfam PF03477 ATP cone domain 24 120 3.0E-17 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 SUPERFAMILY SSF51998 356 910 4.88E-178 T 12-10-2018 AFE_2638 f853fa0fe2875a2c99a1ee26812b9bc7 948 Gene3D G3DSA:3.20.70.20 242 911 1.9E-241 T 12-10-2018 AFE_1454 888b6245d22e3772e67c92836e17d0f7 353 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 10 331 1.5E-107 T 12-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 AFE_1454 888b6245d22e3772e67c92836e17d0f7 353 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 7 328 35.093 T 12-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 AFE_1454 888b6245d22e3772e67c92836e17d0f7 353 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 224 259 1.0E-7 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_1454 888b6245d22e3772e67c92836e17d0f7 353 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 148 181 1.1E-6 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_1454 888b6245d22e3772e67c92836e17d0f7 353 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 260 294 1.4E-4 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_1454 888b6245d22e3772e67c92836e17d0f7 353 SUPERFAMILY SSF51161 34 317 1.34E-73 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFE_1454 888b6245d22e3772e67c92836e17d0f7 353 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 26 91 6.9E-19 T 12-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 AFE_1454 888b6245d22e3772e67c92836e17d0f7 353 Gene3D G3DSA:3.40.1390.10 2 100 2.0E-23 T 12-10-2018 AFE_1454 888b6245d22e3772e67c92836e17d0f7 353 Gene3D G3DSA:2.160.10.10 102 310 2.8E-61 T 12-10-2018 AFE_1438 63136dcbb567a564ec348ce65988a4dd 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 278 2.2E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFE_1438 63136dcbb567a564ec348ce65988a4dd 284 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 21 280 3.3E-82 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 AFE_1438 63136dcbb567a564ec348ce65988a4dd 284 SUPERFAMILY SSF161098 27 273 2.09E-27 T 12-10-2018 IPR035906 MetI-like superfamily AFE_1438 63136dcbb567a564ec348ce65988a4dd 284 Gene3D G3DSA:1.10.3720.10 60 280 2.0E-23 T 12-10-2018 IPR035906 MetI-like superfamily AFE_0531 c06422a7f006d21337e7f80b28becf01 201 Gene3D G3DSA:2.40.160.20 23 184 3.1E-16 T 12-10-2018 AFE_0531 c06422a7f006d21337e7f80b28becf01 201 SUPERFAMILY SSF56925 28 189 9.16E-12 T 12-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel AFE_0531 c06422a7f006d21337e7f80b28becf01 201 Pfam PF13505 Outer membrane protein beta-barrel domain 13 178 3.2E-7 T 12-10-2018 IPR027385 Outer membrane protein beta-barrel AFE_2526 1ccab8334f2249f0f919a89cd7d62422 290 Pfam PF00795 Carbon-nitrogen hydrolase 4 262 6.4E-56 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFE_2526 1ccab8334f2249f0f919a89cd7d62422 290 TIGRFAM TIGR03381 agmatine_aguB: N-carbamoylputrescine amidase 3 279 2.1E-138 T 12-10-2018 IPR017755 N-carbamoylputrescine amidase GO:0006596|GO:0050126 KEGG: 00330+3.5.1.53|MetaCyc: PWY-43 AFE_2526 1ccab8334f2249f0f919a89cd7d62422 290 Gene3D G3DSA:3.60.110.10 1 288 1.0E-108 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFE_2526 1ccab8334f2249f0f919a89cd7d62422 290 SUPERFAMILY SSF56317 3 280 1.09E-81 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFE_2203 aa88218478c7b5f74714a0dd3a2746b0 141 SUPERFAMILY SSF102400 4 139 2.75E-25 T 12-10-2018 IPR036768 DNA polymerase III subunit chi superfamily AFE_2203 aa88218478c7b5f74714a0dd3a2746b0 141 Pfam PF04364 DNA polymerase III chi subunit, HolC 4 134 1.4E-24 T 12-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 AFE_2203 aa88218478c7b5f74714a0dd3a2746b0 141 Gene3D G3DSA:3.40.50.10110 1 139 2.4E-25 T 12-10-2018 IPR036768 DNA polymerase III subunit chi superfamily AFE_3038 153cd887f1222618f7670269ce738917 110 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 102 5.9E-45 T 12-10-2018 IPR004480 Monothiol glutaredoxin-related AFE_3038 153cd887f1222618f7670269ce738917 110 SUPERFAMILY SSF52833 3 105 9.96E-33 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_3038 153cd887f1222618f7670269ce738917 110 Pfam PF00462 Glutaredoxin 17 82 5.7E-19 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFE_3038 153cd887f1222618f7670269ce738917 110 PIRSF PIRSF005894 1 109 1.3E-47 T 12-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 AFE_3038 153cd887f1222618f7670269ce738917 110 Gene3D G3DSA:3.40.30.10 7 103 5.2E-33 T 12-10-2018 AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 PIRSF PIRSF002583 1 629 8.7E-207 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 SUPERFAMILY SSF110942 513 625 1.83E-34 T 12-10-2018 IPR037196 HSP90, C-terminal domain AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 184 5.4E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 625 32.339 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 Gene3D G3DSA:3.30.565.10 1 224 3.4E-74 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 Pfam PF00183 Hsp90 protein 223 625 5.4E-127 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 PRINTS PR00775 90kDa heat shock protein signature 27 49 9.2E-59 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 PRINTS PR00775 90kDa heat shock protein signature 121 143 9.2E-59 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 PRINTS PR00775 90kDa heat shock protein signature 173 190 9.2E-59 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 PRINTS PR00775 90kDa heat shock protein signature 192 210 9.2E-59 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 PRINTS PR00775 90kDa heat shock protein signature 6 26 9.2E-59 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 PRINTS PR00775 90kDa heat shock protein signature 76 93 9.2E-59 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 PRINTS PR00775 90kDa heat shock protein signature 94 111 9.2E-59 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 26 35 - T 12-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 SUPERFAMILY SSF54211 231 486 7.43E-97 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 Gene3D G3DSA:3.30.230.80 230 397 9.3E-69 T 12-10-2018 AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 Gene3D G3DSA:1.20.120.790 494 626 1.3E-43 T 12-10-2018 IPR037196 HSP90, C-terminal domain AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 Gene3D G3DSA:3.40.50.11260 398 487 7.0E-31 T 12-10-2018 AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 SMART SM00387 28 185 2.7E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_3158 330157c796e2a4c145e4dc7f698a5d26 629 SUPERFAMILY SSF55874 6 212 1.57E-63 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_3100 2b17b8084cd8fdaabb910eeccbfc2268 135 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 22 82 2.4E-18 T 12-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain AFE_3100 2b17b8084cd8fdaabb910eeccbfc2268 135 Pfam PF12836 Helix-hairpin-helix motif 23 82 9.7E-23 T 12-10-2018 AFE_3100 2b17b8084cd8fdaabb910eeccbfc2268 135 SMART SM00278 62 81 370.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_3100 2b17b8084cd8fdaabb910eeccbfc2268 135 SMART SM00278 32 51 0.05 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_3100 2b17b8084cd8fdaabb910eeccbfc2268 135 Gene3D G3DSA:1.10.150.320 15 83 2.3E-22 T 12-10-2018 AFE_3100 2b17b8084cd8fdaabb910eeccbfc2268 135 SUPERFAMILY SSF47781 23 80 1.89E-26 T 12-10-2018 IPR010994 RuvA domain 2-like AFE_0450 d01ba631c5bee2a0762f8877aaf5b599 558 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 553 2.1E-157 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 AFE_0450 d01ba631c5bee2a0762f8877aaf5b599 558 SUPERFAMILY SSF52540 2 509 1.18E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0450 d01ba631c5bee2a0762f8877aaf5b599 558 Gene3D G3DSA:3.40.50.300 257 555 4.6E-50 T 12-10-2018 AFE_0450 d01ba631c5bee2a0762f8877aaf5b599 558 PIRSF PIRSF003128 1 558 4.4E-155 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 AFE_0450 d01ba631c5bee2a0762f8877aaf5b599 558 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 510 2.0E-16 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AFE_0450 d01ba631c5bee2a0762f8877aaf5b599 558 SUPERFAMILY SSF52540 1 217 9.38E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0450 d01ba631c5bee2a0762f8877aaf5b599 558 Gene3D G3DSA:3.40.50.300 1 256 7.1E-41 T 12-10-2018 AFE_1577 1a7ba06931c5ffd101a53e2fd7ab0f5a 484 Gene3D G3DSA:1.20.1260.30 1 149 2.9E-46 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily AFE_1577 1a7ba06931c5ffd101a53e2fd7ab0f5a 484 Gene3D G3DSA:3.40.50.150 151 456 8.4E-78 T 12-10-2018 AFE_1577 1a7ba06931c5ffd101a53e2fd7ab0f5a 484 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 310 334 2.2E-17 T 12-10-2018 AFE_1577 1a7ba06931c5ffd101a53e2fd7ab0f5a 484 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 283 295 2.2E-17 T 12-10-2018 AFE_1577 1a7ba06931c5ffd101a53e2fd7ab0f5a 484 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 176 192 2.2E-17 T 12-10-2018 AFE_1577 1a7ba06931c5ffd101a53e2fd7ab0f5a 484 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 200 214 2.2E-17 T 12-10-2018 AFE_1577 1a7ba06931c5ffd101a53e2fd7ab0f5a 484 Pfam PF02384 N-6 DNA Methylase 154 450 9.2E-64 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 AFE_1577 1a7ba06931c5ffd101a53e2fd7ab0f5a 484 Pfam PF12161 HsdM N-terminal domain 6 143 1.5E-11 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain AFE_1577 1a7ba06931c5ffd101a53e2fd7ab0f5a 484 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 286 292 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFE_1577 1a7ba06931c5ffd101a53e2fd7ab0f5a 484 SUPERFAMILY SSF53335 3 484 7.05E-114 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_3024 18fee1a12415ecf7d98370a05b90aeed 113 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 95 1.2E-26 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 AFE_3024 18fee1a12415ecf7d98370a05b90aeed 113 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 1.0E-28 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 AFE_3024 18fee1a12415ecf7d98370a05b90aeed 113 SUPERFAMILY SSF69754 2 102 1.44E-32 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like AFE_3024 18fee1a12415ecf7d98370a05b90aeed 113 Gene3D G3DSA:3.30.160.100 1 98 9.4E-33 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 Gene3D G3DSA:3.40.1190.10 94 311 3.6E-75 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 453 2.3E-162 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 Gene3D G3DSA:3.90.190.20 312 460 9.5E-52 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 SUPERFAMILY SSF53244 313 454 4.21E-43 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 Gene3D G3DSA:3.40.50.720 6 93 6.8E-31 T 12-10-2018 AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 SUPERFAMILY SSF53623 91 312 1.83E-68 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 SUPERFAMILY SSF51984 6 92 2.49E-27 T 12-10-2018 AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 461 42.698 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 Pfam PF01225 Mur ligase family, catalytic domain 7 105 2.1E-27 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 396 2.8E-22 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFE_0205 ea187a2d23d47d06865265552f64f8ef 464 Pfam PF08245 Mur ligase middle domain 110 294 7.2E-26 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFE_2982 7ac6b3f236a3a6607a80d1cc0a0ab3b8 45 Gene3D G3DSA:3.30.2310.20 4 41 4.9E-5 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFE_2091 2c16294343ec3707e52c3a7aa65a93d2 509 SUPERFAMILY SSF103473 11 505 1.03E-64 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_2091 2c16294343ec3707e52c3a7aa65a93d2 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 2.7E-6 T 12-10-2018 AFE_2091 2c16294343ec3707e52c3a7aa65a93d2 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 408 427 2.7E-6 T 12-10-2018 AFE_2091 2c16294343ec3707e52c3a7aa65a93d2 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 2.7E-6 T 12-10-2018 AFE_2091 2c16294343ec3707e52c3a7aa65a93d2 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 210 228 2.7E-6 T 12-10-2018 AFE_2091 2c16294343ec3707e52c3a7aa65a93d2 509 Pfam PF07690 Major Facilitator Superfamily 27 417 1.5E-50 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_2091 2c16294343ec3707e52c3a7aa65a93d2 509 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 498 1.5E-119 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFE_2091 2c16294343ec3707e52c3a7aa65a93d2 509 Gene3D G3DSA:1.20.1250.20 267 504 2.7E-13 T 12-10-2018 AFE_2091 2c16294343ec3707e52c3a7aa65a93d2 509 Gene3D G3DSA:1.20.1720.10 22 266 7.8E-46 T 12-10-2018 AFE_0496 add24aaa9aa808011f126f103b519399 198 Gene3D G3DSA:2.160.10.10 1 176 3.7E-45 T 12-10-2018 AFE_0496 add24aaa9aa808011f126f103b519399 198 SUPERFAMILY SSF51161 7 161 8.87E-31 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFE_0496 add24aaa9aa808011f126f103b519399 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 42 1.8E-5 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_0496 add24aaa9aa808011f126f103b519399 198 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 70 102 2.2E-6 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 PIRSF PIRSF001535 1 569 2.6E-262 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 SUPERFAMILY SSF55826 218 386 1.44E-31 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 456 1.8E-50 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 568 41.355 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 SUPERFAMILY SSF52954 461 567 1.24E-23 T 12-10-2018 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 Gene3D G3DSA:3.40.50.800 4 551 5.6E-238 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 Pfam PF03129 Anticodon binding domain 473 565 2.1E-12 T 12-10-2018 IPR004154 Anticodon-binding AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 Gene3D G3DSA:3.90.960.10 240 385 5.6E-238 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 564 2.4E-222 T 12-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 SUPERFAMILY SSF55681 9 475 1.81E-108 T 12-10-2018 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.4E-19 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.4E-19 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.4E-19 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.4E-19 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 Pfam PF04073 Aminoacyl-tRNA editing domain 256 372 6.5E-24 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFE_2132 6a791b7e94e25391b1e7022998537ca2 570 Gene3D G3DSA:3.30.930.10 11 462 5.6E-238 T 12-10-2018 AFE_0805 acf81c000a543edc52314a4a5e191f3a 514 Pfam PF03321 GH3 auxin-responsive promoter 195 498 8.0E-45 T 12-10-2018 IPR004993 GH3 family Reactome: R-HSA-6798695 AFE_0805 acf81c000a543edc52314a4a5e191f3a 514 Pfam PF03321 GH3 auxin-responsive promoter 25 188 2.9E-19 T 12-10-2018 IPR004993 GH3 family Reactome: R-HSA-6798695 AFE_0805 acf81c000a543edc52314a4a5e191f3a 514 SUPERFAMILY SSF56801 62 387 5.76E-7 T 12-10-2018 AFE_0805 acf81c000a543edc52314a4a5e191f3a 514 Gene3D G3DSA:3.40.50.12780 14 316 6.9E-9 T 12-10-2018 AFE_1035 6ad90edfb90e3d63b1c55a0c83aa9362 129 SUPERFAMILY SSF82199 14 109 3.53E-9 T 12-10-2018 AFE_1035 6ad90edfb90e3d63b1c55a0c83aa9362 129 Gene3D G3DSA:2.170.270.10 10 120 7.7E-9 T 12-10-2018 AFE_1035 6ad90edfb90e3d63b1c55a0c83aa9362 129 Pfam PF00856 SET domain 67 105 2.0E-6 T 12-10-2018 IPR001214 SET domain GO:0005515 AFE_2886 2937589f2ed03c559efac389d41845ee 83 SMART SM00966 8 53 4.6E-7 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_2886 2937589f2ed03c559efac389d41845ee 83 Gene3D G3DSA:2.10.260.10 3 48 6.0E-18 T 12-10-2018 AFE_2886 2937589f2ed03c559efac389d41845ee 83 SUPERFAMILY SSF89447 7 67 1.01E-13 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFE_2886 2937589f2ed03c559efac389d41845ee 83 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 7.6E-7 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_1283 d870603ff387f7025e77d84956f0eed2 269 Pfam PF13708 Domain of unknown function (DUF4942) 75 259 1.0E-56 T 12-10-2018 IPR031339 Domain of unknown function DUF4942 AFE_3060 eecd3a897f8179820e2157009507728e 168 SUPERFAMILY SSF53271 7 140 2.88E-32 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFE_3060 eecd3a897f8179820e2157009507728e 168 Gene3D G3DSA:3.40.50.2020 3 157 6.4E-37 T 12-10-2018 AFE_3060 eecd3a897f8179820e2157009507728e 168 Pfam PF00156 Phosphoribosyl transferase domain 27 136 1.7E-14 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 Gene3D G3DSA:3.40.50.2300 1 129 5.9E-35 T 12-10-2018 AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 SUPERFAMILY SSF52540 142 382 5.67E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 SUPERFAMILY SSF46689 354 442 2.2E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 SUPERFAMILY SSF52172 1 185 8.11E-42 T 12-10-2018 IPR011006 CheY-like superfamily AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 Gene3D G3DSA:1.10.10.60 391 444 3.3E-9 T 12-10-2018 AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 SMART SM00448 4 115 8.5E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 Gene3D G3DSA:3.40.50.300 130 311 1.4E-62 T 12-10-2018 AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 SMART SM00382 161 304 2.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 Pfam PF00072 Response regulator receiver domain 6 115 4.9E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 Pfam PF00158 Sigma-54 interaction domain 142 307 1.1E-69 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_2955 a928676ed6f9fbb2e590d1aa31453a38 457 Gene3D G3DSA:1.10.8.60 312 390 7.0E-24 T 12-10-2018 AFE_1258 f5606c02b6ac0aa2b7db9953c796bc74 429 Gene3D G3DSA:1.10.460.10 166 207 5.6E-8 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFE_1258 f5606c02b6ac0aa2b7db9953c796bc74 429 Gene3D G3DSA:1.10.460.10 325 425 2.0E-7 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFE_1258 f5606c02b6ac0aa2b7db9953c796bc74 429 Pfam PF01131 DNA topoisomerase 159 206 1.4E-8 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFE_1258 f5606c02b6ac0aa2b7db9953c796bc74 429 SMART SM00436 134 224 0.0062 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFE_1258 f5606c02b6ac0aa2b7db9953c796bc74 429 SUPERFAMILY SSF56712 39 255 4.71E-14 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AFE_1258 f5606c02b6ac0aa2b7db9953c796bc74 429 SUPERFAMILY SSF56712 334 417 2.22E-5 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AFE_1811 1c59786d0a0b747b9092771a7468e33b 422 Gene3D G3DSA:2.40.50.100 1 99 3.9E-24 T 12-10-2018 AFE_1811 1c59786d0a0b747b9092771a7468e33b 422 SUPERFAMILY SSF51230 1 90 1.22E-20 T 12-10-2018 IPR011053 Single hybrid motif AFE_1811 1c59786d0a0b747b9092771a7468e33b 422 Gene3D G3DSA:4.10.320.10 153 201 2.0E-5 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFE_1811 1c59786d0a0b747b9092771a7468e33b 422 Pfam PF00364 Biotin-requiring enzyme 4 74 1.6E-12 T 12-10-2018 IPR000089 Biotin/lipoyl attachment AFE_1811 1c59786d0a0b747b9092771a7468e33b 422 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFE_1811 1c59786d0a0b747b9092771a7468e33b 422 SUPERFAMILY SSF52777 204 414 1.51E-40 T 12-10-2018 AFE_1811 1c59786d0a0b747b9092771a7468e33b 422 Gene3D G3DSA:3.30.559.10 202 416 7.1E-43 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFE_1811 1c59786d0a0b747b9092771a7468e33b 422 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 219 412 1.1E-36 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 AFE_2036 749bc55a850e646f4d10b81ac215b207 346 Gene3D G3DSA:2.40.50.100 60 190 2.0E-52 T 12-10-2018 AFE_2036 749bc55a850e646f4d10b81ac215b207 346 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 49 342 9.3E-45 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_2036 749bc55a850e646f4d10b81ac215b207 346 Gene3D G3DSA:2.40.420.20 34 327 2.0E-52 T 12-10-2018 AFE_2036 749bc55a850e646f4d10b81ac215b207 346 Gene3D G3DSA:1.10.287.470 94 158 2.0E-52 T 12-10-2018 AFE_2036 749bc55a850e646f4d10b81ac215b207 346 SUPERFAMILY SSF111369 70 267 3.4E-17 T 12-10-2018 AFE_2036 749bc55a850e646f4d10b81ac215b207 346 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 43 256 4.2E-21 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_2036 749bc55a850e646f4d10b81ac215b207 346 Gene3D G3DSA:2.40.30.170 46 269 2.0E-52 T 12-10-2018 AFE_1930 323d61fe9f595e1b8feba54a24cee9ef 362 PIRSF PIRSF006004 8 359 1.3E-136 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 AFE_1930 323d61fe9f595e1b8feba54a24cee9ef 362 Pfam PF04055 Radical SAM superfamily 116 276 1.3E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_1930 323d61fe9f595e1b8feba54a24cee9ef 362 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 12 351 73.561 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 AFE_1930 323d61fe9f595e1b8feba54a24cee9ef 362 Gene3D G3DSA:3.20.20.70 74 336 5.4E-102 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1930 323d61fe9f595e1b8feba54a24cee9ef 362 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 8 349 4.1E-127 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 AFE_1930 323d61fe9f595e1b8feba54a24cee9ef 362 Gene3D G3DSA:1.10.150.530 12 73 2.4E-20 T 12-10-2018 AFE_1930 323d61fe9f595e1b8feba54a24cee9ef 362 SUPERFAMILY SSF102114 112 334 1.31E-16 T 12-10-2018 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 Gene3D G3DSA:1.10.1060.10 8 143 2.1E-33 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 145 452 5.0E-30 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 SUPERFAMILY SSF51971 143 398 1.12E-67 T 12-10-2018 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 SUPERFAMILY SSF46548 4 155 4.13E-41 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 Gene3D G3DSA:3.50.50.60 282 402 8.0E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 23 131 1.4E-37 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 4 465 6.6E-255 T 12-10-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 PRINTS PR00419 Adrenodoxin reductase family signature 211 221 4.5E-37 T 12-10-2018 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 PRINTS PR00419 Adrenodoxin reductase family signature 321 334 4.5E-37 T 12-10-2018 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 4.5E-37 T 12-10-2018 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 PRINTS PR00419 Adrenodoxin reductase family signature 287 301 4.5E-37 T 12-10-2018 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 4.5E-37 T 12-10-2018 AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 Gene3D G3DSA:3.50.50.60 144 273 4.9E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0729 d5dda2d129ce5f181bfc75368d436f83 465 Gene3D G3DSA:3.50.50.60 404 457 8.0E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1506 0bf7f54a3981c09c075ec00ac5a58c9f 386 TIGRFAM TIGR02660 nifV_homocitr: homocitrate synthase 13 373 9.2E-155 T 12-10-2018 IPR013477 Homocitrate synthase NifV-like GO:0046912|GO:0051188 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 AFE_1506 0bf7f54a3981c09c075ec00ac5a58c9f 386 SUPERFAMILY SSF51569 12 286 5.13E-79 T 12-10-2018 AFE_1506 0bf7f54a3981c09c075ec00ac5a58c9f 386 Gene3D G3DSA:1.10.238.260 276 384 2.4E-26 T 12-10-2018 AFE_1506 0bf7f54a3981c09c075ec00ac5a58c9f 386 Pfam PF00682 HMGL-like 14 269 5.1E-82 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFE_1506 0bf7f54a3981c09c075ec00ac5a58c9f 386 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 19 35 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_1506 0bf7f54a3981c09c075ec00ac5a58c9f 386 Gene3D G3DSA:3.20.20.70 8 273 1.3E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1506 0bf7f54a3981c09c075ec00ac5a58c9f 386 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 Gene3D G3DSA:3.40.50.2000 434 812 9.9E-22 T 12-10-2018 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 SUPERFAMILY SSF53756 906 1211 7.85E-32 T 12-10-2018 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 Pfam PF00534 Glycosyl transferases group 1 622 795 1.9E-8 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 Pfam PF00534 Glycosyl transferases group 1 224 380 4.6E-29 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 Pfam PF00534 Glycosyl transferases group 1 1068 1211 2.1E-19 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 Gene3D G3DSA:3.40.50.2000 18 397 1.1E-46 T 12-10-2018 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 SUPERFAMILY SSF53756 14 401 1.41E-59 T 12-10-2018 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 Gene3D G3DSA:3.40.50.2000 1030 1221 3.3E-22 T 12-10-2018 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 Gene3D G3DSA:3.40.50.2000 200 384 1.1E-46 T 12-10-2018 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 Gene3D G3DSA:3.40.50.2000 613 797 9.9E-22 T 12-10-2018 AFE_2967 c0c8879ca31d0b9244a5d8e051d9f3b2 1915 SUPERFAMILY SSF53756 426 816 1.03E-32 T 12-10-2018 AFE_1554 8790d7a76366d4548f667f720aefa2b5 217 Pfam PF02656 Domain of unknown function (DUF202) 104 180 3.0E-15 T 12-10-2018 IPR003807 Domain of unknown function DUF202 AFE_0246 396abc1f6d8ecc02e479ef290e2262c0 234 PIRSF PIRSF006755 15 225 6.5E-58 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFE_0246 396abc1f6d8ecc02e479ef290e2262c0 234 Gene3D G3DSA:3.40.50.300 16 221 2.1E-57 T 12-10-2018 AFE_0246 396abc1f6d8ecc02e479ef290e2262c0 234 Pfam PF13500 AAA domain 16 218 4.2E-41 T 12-10-2018 AFE_0246 396abc1f6d8ecc02e479ef290e2262c0 234 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 19 186 5.8E-46 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFE_0246 396abc1f6d8ecc02e479ef290e2262c0 234 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 15 217 27.416 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFE_0246 396abc1f6d8ecc02e479ef290e2262c0 234 SUPERFAMILY SSF52540 17 218 3.44E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3067 22d8cd03d1d89ff693634ddea143901d 124 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 105 122 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 AFE_3067 22d8cd03d1d89ff693634ddea143901d 124 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 20 123 8.8E-38 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 AFE_3067 22d8cd03d1d89ff693634ddea143901d 124 Gene3D G3DSA:2.60.300.12 18 124 5.2E-33 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFE_3067 22d8cd03d1d89ff693634ddea143901d 124 SUPERFAMILY SSF89360 18 113 6.47E-31 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFE_3067 22d8cd03d1d89ff693634ddea143901d 124 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 2 124 35.632 T 12-10-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 AFE_3067 22d8cd03d1d89ff693634ddea143901d 124 Pfam PF01521 Iron-sulphur cluster biosynthesis 19 119 3.8E-19 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFE_0078 fea9fba40dde20c7b5a48ff09aa723f8 327 SUPERFAMILY SSF53448 1 291 4.73E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0078 fea9fba40dde20c7b5a48ff09aa723f8 327 Gene3D G3DSA:3.90.550.10 1 245 1.9E-17 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0078 fea9fba40dde20c7b5a48ff09aa723f8 327 Pfam PF00535 Glycosyl transferase family 2 1 106 3.2E-10 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFE_0998 073bad319d03a994952e6c36d9fbd457 243 SUPERFAMILY SSF47413 1 70 1.33E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_0998 073bad319d03a994952e6c36d9fbd457 243 SUPERFAMILY SSF51306 99 228 9.81E-24 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFE_0998 073bad319d03a994952e6c36d9fbd457 243 Pfam PF00717 Peptidase S24-like 146 213 2.6E-14 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFE_0998 073bad319d03a994952e6c36d9fbd457 243 Pfam PF12844 Helix-turn-helix domain 5 68 2.2E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_0998 073bad319d03a994952e6c36d9fbd457 243 SMART SM00530 6 65 2.0E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_0998 073bad319d03a994952e6c36d9fbd457 243 Gene3D G3DSA:1.10.260.40 1 68 1.8E-14 T 12-10-2018 AFE_0998 073bad319d03a994952e6c36d9fbd457 243 Gene3D G3DSA:2.10.109.10 107 232 4.4E-14 T 12-10-2018 AFE_1443 6c5cc9eae9087d027ee6b8f14c3fc6f3 196 Pfam PF09335 SNARE associated Golgi protein 35 156 7.5E-15 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFE_3108 1e7a34abe6e96b5c2fdce58675396756 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_3108 1e7a34abe6e96b5c2fdce58675396756 263 SUPERFAMILY SSF51735 10 243 1.64E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3108 1e7a34abe6e96b5c2fdce58675396756 263 Gene3D G3DSA:3.40.50.720 3 246 5.8E-58 T 12-10-2018 AFE_3108 1e7a34abe6e96b5c2fdce58675396756 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.4E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3108 1e7a34abe6e96b5c2fdce58675396756 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.4E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3108 1e7a34abe6e96b5c2fdce58675396756 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.4E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3108 1e7a34abe6e96b5c2fdce58675396756 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.4E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3108 1e7a34abe6e96b5c2fdce58675396756 263 Pfam PF00106 short chain dehydrogenase 15 206 9.2E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2076 cd553792bcea74e3066cbb696b2c6788 185 Pfam PF12804 MobA-like NTP transferase domain 8 156 2.6E-35 T 12-10-2018 IPR025877 MobA-like NTP transferase AFE_2076 cd553792bcea74e3066cbb696b2c6788 185 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 7 184 6.0E-55 T 12-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 AFE_2076 cd553792bcea74e3066cbb696b2c6788 185 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 4 177 21.632 T 12-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 AFE_2076 cd553792bcea74e3066cbb696b2c6788 185 Gene3D G3DSA:3.90.550.10 5 185 1.5E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2076 cd553792bcea74e3066cbb696b2c6788 185 SUPERFAMILY SSF53448 5 183 8.56E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0628 55226156f571dd2bf86d53ef074f27ed 218 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 175 218 2.0E-20 T 12-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFE_0628 55226156f571dd2bf86d53ef074f27ed 218 SUPERFAMILY SSF50475 19 218 2.36E-61 T 12-10-2018 AFE_0628 55226156f571dd2bf86d53ef074f27ed 218 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 13 218 35.861 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFE_0628 55226156f571dd2bf86d53ef074f27ed 218 Gene3D G3DSA:2.30.110.10 4 218 7.7E-78 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFE_0628 55226156f571dd2bf86d53ef074f27ed 218 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 34 120 5.3E-24 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFE_0628 55226156f571dd2bf86d53ef074f27ed 218 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 5 218 8.1E-73 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFE_0628 55226156f571dd2bf86d53ef074f27ed 218 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 185 198 - T 12-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFE_0628 55226156f571dd2bf86d53ef074f27ed 218 PIRSF PIRSF000190 2 218 1.2E-72 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFE_2264 bc30f567490cbbb50aa012821b558a70 363 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 343 45.57 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AFE_2264 bc30f567490cbbb50aa012821b558a70 363 Gene3D G3DSA:3.20.20.70 2 343 8.9E-126 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2264 bc30f567490cbbb50aa012821b558a70 363 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 361 5.3E-119 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 AFE_2264 bc30f567490cbbb50aa012821b558a70 363 SUPERFAMILY SSF51395 1 361 5.19E-96 T 12-10-2018 AFE_2264 bc30f567490cbbb50aa012821b558a70 363 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 299 319 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AFE_2264 bc30f567490cbbb50aa012821b558a70 363 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AFE_2264 bc30f567490cbbb50aa012821b558a70 363 Pfam PF01180 Dihydroorotate dehydrogenase 50 344 4.7E-83 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 AFE_2674 51f73fab2f74420da73081d174700010 598 Pfam PF01432 Peptidase family M3 339 581 1.8E-31 T 12-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 AFE_2674 51f73fab2f74420da73081d174700010 598 Gene3D G3DSA:1.20.140.70 41 171 1.7E-11 T 12-10-2018 AFE_2674 51f73fab2f74420da73081d174700010 598 Gene3D G3DSA:1.10.1370.20 226 597 4.3E-111 T 12-10-2018 AFE_2674 51f73fab2f74420da73081d174700010 598 Pfam PF08439 Oligopeptidase F 121 187 1.0E-14 T 12-10-2018 IPR013647 Oligopeptidase F, N-terminal domain AFE_2674 51f73fab2f74420da73081d174700010 598 SUPERFAMILY SSF55486 58 595 1.92E-94 T 12-10-2018 AFE_1763 26c64adae26fb64cc8a948a29a92a565 402 SUPERFAMILY SSF53756 23 386 8.37E-59 T 12-10-2018 AFE_1763 26c64adae26fb64cc8a948a29a92a565 402 Gene3D G3DSA:3.40.50.2000 189 373 7.3E-39 T 12-10-2018 AFE_1763 26c64adae26fb64cc8a948a29a92a565 402 Pfam PF00534 Glycosyl transferases group 1 225 368 4.9E-25 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1763 26c64adae26fb64cc8a948a29a92a565 402 Gene3D G3DSA:3.40.50.2000 27 188 2.9E-10 T 12-10-2018 AFE_1763 26c64adae26fb64cc8a948a29a92a565 402 Pfam PF13439 Glycosyltransferase Family 4 31 180 9.6E-12 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_3027 6748224234ebe934da5c6f543b1713f0 182 Pfam PF03968 OstA-like protein 45 152 1.2E-21 T 12-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal AFE_3027 6748224234ebe934da5c6f543b1713f0 182 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 37 170 2.4E-38 T 12-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 AFE_3027 6748224234ebe934da5c6f543b1713f0 182 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 1 171 19.146 T 12-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 AFE_3027 6748224234ebe934da5c6f543b1713f0 182 Gene3D G3DSA:2.60.450.10 40 168 4.9E-31 T 12-10-2018 AFE_2633 a7db26ce2474df845bef63ce74453511 257 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 54.806 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2633 a7db26ce2474df845bef63ce74453511 257 SUPERFAMILY SSF51351 2 250 4.45E-84 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2633 a7db26ce2474df845bef63ce74453511 257 Pfam PF00121 Triosephosphate isomerase 5 247 2.6E-84 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2633 a7db26ce2474df845bef63ce74453511 257 ProSitePatterns PS00171 Triosephosphate isomerase active site. 166 176 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2633 a7db26ce2474df845bef63ce74453511 257 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.1E-56 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2633 a7db26ce2474df845bef63ce74453511 257 Gene3D G3DSA:3.20.20.70 1 255 9.9E-94 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1422 d0d02463ef579bb02b6507e5611edd22 273 SUPERFAMILY SSF56300 19 266 4.75E-31 T 12-10-2018 AFE_1422 d0d02463ef579bb02b6507e5611edd22 273 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 20 242 2.1E-13 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFE_1422 d0d02463ef579bb02b6507e5611edd22 273 Gene3D G3DSA:3.60.21.10 19 264 1.6E-15 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFE_1096 c3f3951159023026d3f6acba2d0a5d70 416 Pfam PF06834 TraU protein 43 318 6.3E-50 T 12-10-2018 IPR009649 TraU AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 593 49.638 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 343 572 4.2E-80 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 Pfam PF13721 SecD export protein N-terminal TM region 1 98 4.2E-21 T 12-10-2018 IPR027398 SecD export protein N-terminal TM domain AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 120 579 4.8E-147 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 Gene3D G3DSA:3.30.70.3400 217 413 7.0E-65 T 12-10-2018 AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 Gene3D G3DSA:3.30.1360.200 275 411 7.0E-65 T 12-10-2018 AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 Pfam PF02355 Protein export membrane protein 414 580 4.0E-23 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 Gene3D G3DSA:1.20.1640.10 414 588 4.7E-8 T 12-10-2018 AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 SUPERFAMILY SSF82866 390 582 7.59E-42 T 12-10-2018 AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 Pfam PF07549 SecD/SecF GG Motif 112 138 7.2E-8 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 PRINTS PR00702 Acriflavin resistance protein family signature 429 452 1.2E-6 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 PRINTS PR00702 Acriflavin resistance protein family signature 482 506 1.2E-6 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_2057 cc2e96b1617e3297b5fde9b7f9484c69 594 PRINTS PR00702 Acriflavin resistance protein family signature 557 580 1.2E-6 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 Pfam PF14622 Ribonuclease-III-like 18 137 1.8E-31 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 SUPERFAMILY SSF69065 3 157 4.36E-46 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 SMART SM00358 154 221 3.9E-19 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 Gene3D G3DSA:3.30.160.20 152 225 1.7E-18 T 12-10-2018 AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 Pfam PF00035 Double-stranded RNA binding motif 154 220 1.6E-13 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 SUPERFAMILY SSF54768 107 221 9.26E-25 T 12-10-2018 AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 Hamap MF_00104 Ribonuclease 3 [rnc]. 7 217 27.772 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 SMART SM00535 19 147 2.4E-46 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 Gene3D G3DSA:1.10.1520.10 1 145 5.2E-44 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 7 219 7.5E-68 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 AFE_1400 823d5b142688cd9f7e029cfa5e560628 226 ProSitePatterns PS00517 Ribonuclease III family signature. 36 44 - T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFE_2845 6985adb0149bc9509a6204e5f2790246 156 Hamap MF_00984 Single-stranded DNA-binding protein. 4 111 36.889 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFE_2845 6985adb0149bc9509a6204e5f2790246 156 SUPERFAMILY SSF50249 3 156 2.64E-56 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_2845 6985adb0149bc9509a6204e5f2790246 156 Pfam PF00436 Single-strand binding protein family 4 106 3.5E-41 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AFE_2845 6985adb0149bc9509a6204e5f2790246 156 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 156 2.3E-53 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFE_2845 6985adb0149bc9509a6204e5f2790246 156 Gene3D G3DSA:2.40.50.140 1 120 1.0E-46 T 12-10-2018 AFE_1932 eaeb2e23d36ab64464ef6cb7ff8e7fcc 324 Gene3D G3DSA:1.10.260.40 2 89 5.5E-26 T 12-10-2018 AFE_1932 eaeb2e23d36ab64464ef6cb7ff8e7fcc 324 Pfam PF13413 Helix-turn-helix domain 11 71 8.6E-25 T 12-10-2018 AFE_1932 eaeb2e23d36ab64464ef6cb7ff8e7fcc 324 Pfam PF13464 Domain of unknown function (DUF4115) 195 267 3.9E-17 T 12-10-2018 IPR025194 Domain of unknown function DUF4115 AFE_1932 eaeb2e23d36ab64464ef6cb7ff8e7fcc 324 SMART SM00530 10 71 1.5E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_1932 eaeb2e23d36ab64464ef6cb7ff8e7fcc 324 SUPERFAMILY SSF47413 1 76 7.78E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 SUPERFAMILY SSF56672 12 245 1.33E-93 T 12-10-2018 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 Gene3D G3DSA:3.30.1490.100 251 360 3.4E-25 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 Gene3D G3DSA:3.30.70.270 127 184 6.4E-22 T 12-10-2018 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 Gene3D G3DSA:1.10.150.20 185 247 1.9E-19 T 12-10-2018 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 Pfam PF11798 IMS family HHH motif 178 208 3.9E-7 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 SUPERFAMILY SSF100879 249 354 1.61E-24 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 Gene3D G3DSA:2.30.40.20 23 82 1.8E-28 T 12-10-2018 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 Gene3D G3DSA:3.30.70.270 83 126 3.7E-10 T 12-10-2018 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 Pfam PF00817 impB/mucB/samB family 18 165 3.5E-53 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 Pfam PF11799 impB/mucB/samB family C-terminal domain 244 356 4.6E-14 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFE_2654 0f7cf551cf4e6be4056f672503193fd0 378 Hamap MF_01113 DNA polymerase IV [dinB]. 12 370 39.127 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 Pfam PF07503 HypF finger 115 148 4.7E-15 T 12-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 Pfam PF07503 HypF finger 165 198 2.6E-15 T 12-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 Pfam PF00708 Acylphosphatase 14 95 1.9E-16 T 12-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 PIRSF PIRSF006256 9 793 1.2E-274 T 12-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 ProSitePatterns PS00150 Acylphosphatase signature 1. 17 27 - T 12-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 Gene3D G3DSA:3.30.420.350 501 772 6.8E-114 T 12-10-2018 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 SUPERFAMILY SSF54975 14 95 4.14E-20 T 12-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 Gene3D G3DSA:3.90.870.50 15 374 1.6E-143 T 12-10-2018 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 Gene3D G3DSA:3.30.420.360 395 784 6.8E-114 T 12-10-2018 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 Pfam PF01300 Telomere recombination 222 396 6.4E-53 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 Gene3D G3DSA:3.30.110.120 265 383 1.6E-143 T 12-10-2018 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 15 784 1.4E-231 T 12-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 AFE_0712 b5a5ed952a50f66a84606f16c130d2d2 803 SUPERFAMILY SSF55821 182 402 9.16E-52 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFE_2640 69b487ab8aa14c4c7da9c79dae90ffec 89 SUPERFAMILY SSF56281 5 69 1.97E-5 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_2640 69b487ab8aa14c4c7da9c79dae90ffec 89 Gene3D G3DSA:3.60.15.10 1 88 3.3E-16 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_0349 511517ee4faf294d46bef3a11bf540ce 72 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 8.9E-26 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 AFE_0349 511517ee4faf294d46bef3a11bf540ce 72 SUPERFAMILY SSF50249 1 70 6.57E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0349 511517ee4faf294d46bef3a11bf540ce 72 Gene3D G3DSA:2.40.50.140 1 72 1.7E-35 T 12-10-2018 AFE_0349 511517ee4faf294d46bef3a11bf540ce 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 4.6E-37 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AFE_0349 511517ee4faf294d46bef3a11bf540ce 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.121 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AFE_0349 511517ee4faf294d46bef3a11bf540ce 72 SMART SM00316 4 72 7.4E-4 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_0614 871aeb16769d23f5f97ab0b5648a6a68 409 SUPERFAMILY SSF53756 195 368 1.26E-16 T 12-10-2018 AFE_0614 871aeb16769d23f5f97ab0b5648a6a68 409 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 230 366 9.3E-9 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 AFE_0614 871aeb16769d23f5f97ab0b5648a6a68 409 Gene3D G3DSA:3.40.50.2000 217 373 3.7E-22 T 12-10-2018 AFE_1464 cde176f0f08436547981251aeba9412a 464 Pfam PF01171 PP-loop family 29 201 2.3E-45 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AFE_1464 cde176f0f08436547981251aeba9412a 464 Gene3D G3DSA:3.40.50.620 23 235 7.1E-66 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_1464 cde176f0f08436547981251aeba9412a 464 SUPERFAMILY SSF82829 255 315 1.02E-7 T 12-10-2018 AFE_1464 cde176f0f08436547981251aeba9412a 464 SUPERFAMILY SSF56037 343 449 1.39E-14 T 12-10-2018 AFE_1464 cde176f0f08436547981251aeba9412a 464 SMART SM00977 377 448 1.0E-10 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFE_1464 cde176f0f08436547981251aeba9412a 464 SUPERFAMILY SSF52402 25 228 6.17E-56 T 12-10-2018 AFE_1464 cde176f0f08436547981251aeba9412a 464 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 377 420 7.9E-11 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFE_1464 cde176f0f08436547981251aeba9412a 464 Pfam PF11734 TilS substrate C-terminal domain 380 435 3.8E-11 T 12-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFE_1464 cde176f0f08436547981251aeba9412a 464 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 13 315 22.099 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFE_1464 cde176f0f08436547981251aeba9412a 464 Pfam PF09179 TilS substrate binding domain 256 313 3.2E-6 T 12-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFE_1464 cde176f0f08436547981251aeba9412a 464 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 29 205 2.6E-46 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFE_0198 31df82ff6620ba60b206d2e377bbf151 125 Pfam PF01638 HxlR-like helix-turn-helix 20 107 4.0E-21 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type AFE_0198 31df82ff6620ba60b206d2e377bbf151 125 Gene3D G3DSA:1.10.10.10 2 124 1.2E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0198 31df82ff6620ba60b206d2e377bbf151 125 SUPERFAMILY SSF46785 8 108 1.68E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2862 d48dd8ef04a557628a9a3ad697ced705 592 Gene3D G3DSA:3.40.50.300 331 572 4.4E-63 T 12-10-2018 AFE_2862 d48dd8ef04a557628a9a3ad697ced705 592 Gene3D G3DSA:3.40.50.300 2 233 1.9E-60 T 12-10-2018 AFE_2862 d48dd8ef04a557628a9a3ad697ced705 592 SUPERFAMILY SSF52540 341 562 5.54E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2862 d48dd8ef04a557628a9a3ad697ced705 592 SMART SM00382 36 217 1.1E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2862 d48dd8ef04a557628a9a3ad697ced705 592 SMART SM00382 367 557 3.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2862 d48dd8ef04a557628a9a3ad697ced705 592 Pfam PF00005 ABC transporter 360 502 1.3E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2862 d48dd8ef04a557628a9a3ad697ced705 592 Pfam PF00005 ABC transporter 27 170 3.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2862 d48dd8ef04a557628a9a3ad697ced705 592 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2862 d48dd8ef04a557628a9a3ad697ced705 592 SUPERFAMILY SSF52540 8 228 7.99E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0934 c841361092971d4ef4bc2497efe76324 877 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 654 697 1.1E-19 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFE_0934 c841361092971d4ef4bc2497efe76324 877 SMART SM00863 654 697 6.4E-23 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFE_0934 c841361092971d4ef4bc2497efe76324 877 Pfam PF02272 DHHA1 domain 734 872 5.3E-27 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFE_0934 c841361092971d4ef4bc2497efe76324 877 SUPERFAMILY SSF101353 245 456 3.4E-60 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AFE_0934 c841361092971d4ef4bc2497efe76324 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 198 209 1.0E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFE_0934 c841361092971d4ef4bc2497efe76324 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 299 312 1.0E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFE_0934 c841361092971d4ef4bc2497efe76324 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 225 238 1.0E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFE_0934 c841361092971d4ef4bc2497efe76324 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 1.0E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFE_0934 c841361092971d4ef4bc2497efe76324 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 275 291 1.0E-32 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFE_0934 c841361092971d4ef4bc2497efe76324 877 Gene3D G3DSA:3.10.310.40 764 874 1.4E-28 T 12-10-2018 AFE_0934 c841361092971d4ef4bc2497efe76324 877 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 876 202.052 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 AFE_0934 c841361092971d4ef4bc2497efe76324 877 SUPERFAMILY SSF55681 3 244 4.31E-111 T 12-10-2018 AFE_0934 c841361092971d4ef4bc2497efe76324 877 SUPERFAMILY SSF55186 553 712 4.32E-50 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 AFE_0934 c841361092971d4ef4bc2497efe76324 877 Pfam PF01411 tRNA synthetases class II (A) 6 555 5.5E-234 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 AFE_0934 c841361092971d4ef4bc2497efe76324 877 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 854 0.0 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFE_0934 c841361092971d4ef4bc2497efe76324 877 Gene3D G3DSA:3.30.980.10 564 698 5.0E-49 T 12-10-2018 AFE_0934 c841361092971d4ef4bc2497efe76324 877 Gene3D G3DSA:3.30.54.20 625 678 5.0E-49 T 12-10-2018 AFE_0934 c841361092971d4ef4bc2497efe76324 877 Gene3D G3DSA:2.40.30.130 462 553 7.5E-10 T 12-10-2018 AFE_0934 c841361092971d4ef4bc2497efe76324 877 SUPERFAMILY SSF50447 454 553 1.22E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_0934 c841361092971d4ef4bc2497efe76324 877 Gene3D G3DSA:3.30.930.10 1 241 1.5E-114 T 12-10-2018 AFE_2936 3ee596a7fc2ec18b13eb560756560460 550 Pfam PF07715 TonB-dependent Receptor Plug Domain 71 179 4.0E-7 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain AFE_2936 3ee596a7fc2ec18b13eb560756560460 550 Gene3D G3DSA:2.170.130.10 68 200 8.2E-9 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_2936 3ee596a7fc2ec18b13eb560756560460 550 Gene3D G3DSA:2.40.170.20 203 549 9.2E-14 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily AFE_2936 3ee596a7fc2ec18b13eb560756560460 550 Pfam PF00593 TonB dependent receptor 331 544 7.8E-7 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_2936 3ee596a7fc2ec18b13eb560756560460 550 SUPERFAMILY SSF56935 39 544 4.03E-37 T 12-10-2018 AFE_2298 75ae3797971881e85da5efab99ba2d67 735 Pfam PF07715 TonB-dependent Receptor Plug Domain 76 177 1.1E-7 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain AFE_2298 75ae3797971881e85da5efab99ba2d67 735 Gene3D G3DSA:2.40.170.20 207 735 1.2E-54 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily AFE_2298 75ae3797971881e85da5efab99ba2d67 735 Gene3D G3DSA:2.170.130.10 62 181 4.7E-7 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_2298 75ae3797971881e85da5efab99ba2d67 735 Pfam PF00593 TonB dependent receptor 267 732 7.8E-29 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_2298 75ae3797971881e85da5efab99ba2d67 735 SUPERFAMILY SSF56935 70 735 2.27E-66 T 12-10-2018 AFE_2727 d8e86e3fafafbb4dccc9c047cd7503e4 217 PIRSF PIRSF000005 3 217 3.4E-62 T 12-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 AFE_2727 d8e86e3fafafbb4dccc9c047cd7503e4 217 Pfam PF00034 Cytochrome c 130 217 1.7E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_2727 d8e86e3fafafbb4dccc9c047cd7503e4 217 Pfam PF00034 Cytochrome c 43 118 2.6E-8 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_2727 d8e86e3fafafbb4dccc9c047cd7503e4 217 Gene3D G3DSA:1.10.760.10 123 216 1.3E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_2727 d8e86e3fafafbb4dccc9c047cd7503e4 217 SUPERFAMILY SSF46626 125 216 2.04E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_2727 d8e86e3fafafbb4dccc9c047cd7503e4 217 Gene3D G3DSA:1.10.760.10 40 118 3.9E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_2727 d8e86e3fafafbb4dccc9c047cd7503e4 217 SUPERFAMILY SSF46626 45 118 4.28E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 Gene3D G3DSA:3.30.70.260 679 750 6.4E-8 T 12-10-2018 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 Pfam PF01842 ACT domain 679 727 1.8E-7 T 12-10-2018 IPR002912 ACT domain AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 SUPERFAMILY SSF55021 675 748 4.93E-11 T 12-10-2018 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 SUPERFAMILY SSF81593 190 302 2.2E-7 T 12-10-2018 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 SUPERFAMILY SSF81301 34 162 3.27E-17 T 12-10-2018 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 Pfam PF01909 Nucleotidyltransferase domain 65 93 4.4E-5 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 Gene3D G3DSA:1.10.3210.10 426 569 7.0E-10 T 12-10-2018 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 Pfam PF08335 GlnD PII-uridylyltransferase 170 305 7.3E-27 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 SMART SM00471 437 583 1.3E-7 T 12-10-2018 IPR003607 HD/PDEase domain AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 SUPERFAMILY SSF81891 344 583 4.32E-16 T 12-10-2018 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 862 242.942 T 12-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 SUPERFAMILY SSF55021 785 856 6.66E-8 T 12-10-2018 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 Pfam PF01966 HD domain 467 569 7.6E-13 T 12-10-2018 IPR006674 HD domain AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 29 853 3.1E-233 T 12-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 AFE_0924 4ac944cb45e140751c6616b3d98207aa 862 PIRSF PIRSF006288 2 862 3.5E-256 T 12-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 AFE_2156 6385740e597306c58ac9bbaf0414bc38 272 Gene3D G3DSA:3.40.50.300 22 191 2.7E-29 T 12-10-2018 AFE_2156 6385740e597306c58ac9bbaf0414bc38 272 SUPERFAMILY SSF52540 22 225 7.29E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2156 6385740e597306c58ac9bbaf0414bc38 272 Pfam PF07728 AAA domain (dynein-related subfamily) 39 173 4.1E-31 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFE_2156 6385740e597306c58ac9bbaf0414bc38 272 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 186 269 1.5E-30 T 12-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal AFE_1509 11e65b4e599ce11de4bf9a3419f575bd 122 SUPERFAMILY SSF89360 1 95 5.1E-30 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFE_1509 11e65b4e599ce11de4bf9a3419f575bd 122 Gene3D G3DSA:2.60.300.12 1 108 2.5E-35 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFE_1509 11e65b4e599ce11de4bf9a3419f575bd 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 105 2.0E-36 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 AFE_1509 11e65b4e599ce11de4bf9a3419f575bd 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 101 3.2E-22 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFE_1509 11e65b4e599ce11de4bf9a3419f575bd 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 87 104 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 AFE_2553 99e78bf1c9c63c9609d10a6d73105125 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-5 T 12-10-2018 AFE_2553 99e78bf1c9c63c9609d10a6d73105125 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 1.3E-5 T 12-10-2018 AFE_2553 99e78bf1c9c63c9609d10a6d73105125 351 Gene3D G3DSA:3.50.50.60 2 153 2.2E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2553 99e78bf1c9c63c9609d10a6d73105125 351 Gene3D G3DSA:3.50.50.60 195 343 1.5E-6 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2553 99e78bf1c9c63c9609d10a6d73105125 351 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 332 6.4E-18 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_2553 99e78bf1c9c63c9609d10a6d73105125 351 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 4.6E-8 T 12-10-2018 AFE_2553 99e78bf1c9c63c9609d10a6d73105125 351 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 313 320 4.6E-8 T 12-10-2018 AFE_2553 99e78bf1c9c63c9609d10a6d73105125 351 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.6E-8 T 12-10-2018 AFE_2553 99e78bf1c9c63c9609d10a6d73105125 351 SUPERFAMILY SSF51971 7 343 5.65E-24 T 12-10-2018 AFE_3070 07fd673e82c05ccc38e3a20d8a44218a 327 TIGRFAM TIGR03182 PDH_E1_alph_y: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 7 319 1.9E-124 T 12-10-2018 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y GO:0004739|GO:0006086|GO:0043231 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 AFE_3070 07fd673e82c05ccc38e3a20d8a44218a 327 Pfam PF00676 Dehydrogenase E1 component 12 308 4.5E-77 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 AFE_3070 07fd673e82c05ccc38e3a20d8a44218a 327 Gene3D G3DSA:3.40.50.970 1 326 1.6E-117 T 12-10-2018 AFE_3070 07fd673e82c05ccc38e3a20d8a44218a 327 SUPERFAMILY SSF52518 6 320 6.13E-92 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_0991 e1d961099051bd73e9cd2cf3b3fa0a20 255 Gene3D G3DSA:3.30.1330.30 1 74 6.9E-13 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like AFE_0991 e1d961099051bd73e9cd2cf3b3fa0a20 255 SUPERFAMILY SSF55315 4 70 7.89E-10 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like AFE_0991 e1d961099051bd73e9cd2cf3b3fa0a20 255 Pfam PF00588 SpoU rRNA Methylase family 95 234 1.5E-37 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFE_0991 e1d961099051bd73e9cd2cf3b3fa0a20 255 SUPERFAMILY SSF75217 87 241 7.85E-47 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFE_0991 e1d961099051bd73e9cd2cf3b3fa0a20 255 SMART SM00967 5 80 2.2E-7 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFE_0991 e1d961099051bd73e9cd2cf3b3fa0a20 255 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 4 240 1.9E-68 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 AFE_0991 e1d961099051bd73e9cd2cf3b3fa0a20 255 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 70 2.4E-10 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFE_0991 e1d961099051bd73e9cd2cf3b3fa0a20 255 Gene3D G3DSA:3.40.1280.10 77 241 9.5E-59 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFE_1363 c35cdcbb13032032b1411149388aa5ea 134 Pfam PF01909 Nucleotidyltransferase domain 33 109 1.3E-9 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFE_1363 c35cdcbb13032032b1411149388aa5ea 134 Gene3D G3DSA:3.30.460.10 18 134 2.1E-14 T 12-10-2018 AFE_1363 c35cdcbb13032032b1411149388aa5ea 134 SUPERFAMILY SSF81301 33 133 2.73E-15 T 12-10-2018 AFE_0260 f978f6d0cd4a2db677fe3917abb04f31 116 Hamap MF_00634 UPF0235 protein YggU [yggU]. 14 101 17.703 T 12-10-2018 IPR003746 Protein of unknown function DUF167 AFE_0260 f978f6d0cd4a2db677fe3917abb04f31 116 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 18 88 9.8E-23 T 12-10-2018 IPR003746 Protein of unknown function DUF167 AFE_0260 f978f6d0cd4a2db677fe3917abb04f31 116 SUPERFAMILY SSF69786 8 98 6.54E-25 T 12-10-2018 IPR036591 YggU-like superfamily AFE_0260 f978f6d0cd4a2db677fe3917abb04f31 116 Gene3D G3DSA:3.30.1200.10 8 109 1.9E-28 T 12-10-2018 IPR036591 YggU-like superfamily AFE_0260 f978f6d0cd4a2db677fe3917abb04f31 116 SMART SM01152 14 90 2.8E-33 T 12-10-2018 IPR003746 Protein of unknown function DUF167 AFE_1924 0fead3fcb18bfe4f718df3562631b498 449 PIRSF PIRSF000521 31 317 3.3E-19 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFE_1924 0fead3fcb18bfe4f718df3562631b498 449 PIRSF PIRSF000521 396 446 310.0 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFE_1924 0fead3fcb18bfe4f718df3562631b498 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 253 290 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFE_1924 0fead3fcb18bfe4f718df3562631b498 449 SUPERFAMILY SSF53383 10 444 1.15E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_1924 0fead3fcb18bfe4f718df3562631b498 449 Gene3D G3DSA:3.90.1150.10 11 444 6.9E-142 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_1924 0fead3fcb18bfe4f718df3562631b498 449 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 16 444 2.6E-142 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 AFE_1924 0fead3fcb18bfe4f718df3562631b498 449 Gene3D G3DSA:3.40.640.10 65 343 6.9E-142 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_1924 0fead3fcb18bfe4f718df3562631b498 449 Pfam PF00202 Aminotransferase class-III 31 443 9.1E-102 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFE_1913 9dbd1cbfae882063589dac5528f0d279 214 ProSitePatterns PS01331 Thymidylate kinase signature. 98 110 - T 12-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFE_1913 9dbd1cbfae882063589dac5528f0d279 214 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 8 201 4.5E-45 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFE_1913 9dbd1cbfae882063589dac5528f0d279 214 SUPERFAMILY SSF52540 8 201 1.97E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1913 9dbd1cbfae882063589dac5528f0d279 214 Hamap MF_00165 Thymidylate kinase [tmk]. 10 209 25.453 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFE_1913 9dbd1cbfae882063589dac5528f0d279 214 Gene3D G3DSA:3.40.50.300 5 209 9.3E-55 T 12-10-2018 AFE_1913 9dbd1cbfae882063589dac5528f0d279 214 Pfam PF02223 Thymidylate kinase 14 200 3.6E-41 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AFE_0869 e202baf57dc63fed22fbdce03d3e51da 80 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 54 1.2E-8 T 12-10-2018 AFE_0869 e202baf57dc63fed22fbdce03d3e51da 80 SUPERFAMILY SSF143120 1 77 2.35E-20 T 12-10-2018 IPR036165 YefM-like superfamily AFE_0869 e202baf57dc63fed22fbdce03d3e51da 80 Gene3D G3DSA:3.40.1620.40 2 67 4.2E-23 T 12-10-2018 AFE_0869 e202baf57dc63fed22fbdce03d3e51da 80 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 69 9.5E-19 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM AFE_1967 8d82237cbf46dc442c627a4470fd1d35 329 Gene3D G3DSA:3.40.50.720 3 321 1.3E-121 T 12-10-2018 AFE_1967 8d82237cbf46dc442c627a4470fd1d35 329 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 3 326 1.8E-125 T 12-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 AFE_1967 8d82237cbf46dc442c627a4470fd1d35 329 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 327 48.013 T 12-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 AFE_1967 8d82237cbf46dc442c627a4470fd1d35 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 239 1.9E-44 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFE_1967 8d82237cbf46dc442c627a4470fd1d35 329 Gene3D G3DSA:3.90.25.10 166 308 1.3E-121 T 12-10-2018 AFE_1967 8d82237cbf46dc442c627a4470fd1d35 329 SUPERFAMILY SSF51735 3 327 4.0E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1611 a7b812401d96fbdbb67fba7f2f52755d 336 Pfam PF01609 Transposase DDE domain 26 297 1.8E-24 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 AFE_1611 a7b812401d96fbdbb67fba7f2f52755d 336 SUPERFAMILY SSF53098 24 306 2.12E-13 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_0530 d0711b93b964605e4a3391cde0390b6f 313 SUPERFAMILY SSF53613 2 298 2.81E-63 T 12-10-2018 IPR029056 Ribokinase-like AFE_0530 d0711b93b964605e4a3391cde0390b6f 313 Pfam PF00294 pfkB family carbohydrate kinase 35 292 1.3E-37 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFE_0530 d0711b93b964605e4a3391cde0390b6f 313 Gene3D G3DSA:3.40.1190.20 1 312 6.0E-108 T 12-10-2018 IPR029056 Ribokinase-like AFE_0530 d0711b93b964605e4a3391cde0390b6f 313 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFE_2882 48c2384da753234bd334c9b9b5abec47 308 SUPERFAMILY SSF52141 125 305 4.91E-61 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_2882 48c2384da753234bd334c9b9b5abec47 308 Pfam PF03167 Uracil DNA glycosylase superfamily 150 297 3.3E-44 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_2882 48c2384da753234bd334c9b9b5abec47 308 SMART SM00987 150 297 5.7E-40 T 12-10-2018 AFE_2882 48c2384da753234bd334c9b9b5abec47 308 Gene3D G3DSA:3.40.470.10 125 308 1.7E-69 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_2882 48c2384da753234bd334c9b9b5abec47 308 SMART SM00986 150 297 5.7E-40 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_2882 48c2384da753234bd334c9b9b5abec47 308 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 136 299 1.7E-62 T 12-10-2018 IPR005273 Uracil-DNA glycosylase family 4 AFE_2914 bbfbf962b76660c353dc0adfcafff4d5 390 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 49 390 2.0E-65 T 12-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 AFE_0318 f987569a9157bd9ff0461abffd34f434 128 SUPERFAMILY SSF48300 4 64 2.09E-16 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0318 f987569a9157bd9ff0461abffd34f434 128 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 62 128 8.9E-30 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0318 f987569a9157bd9ff0461abffd34f434 128 Gene3D G3DSA:3.30.1390.10 58 128 1.0E-29 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFE_0318 f987569a9157bd9ff0461abffd34f434 128 SUPERFAMILY SSF54736 57 128 8.55E-24 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFE_0318 f987569a9157bd9ff0461abffd34f434 128 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 128 1.8E-47 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0318 f987569a9157bd9ff0461abffd34f434 128 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 128 6.0E-22 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0318 f987569a9157bd9ff0461abffd34f434 128 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 50 5.7E-19 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0318 f987569a9157bd9ff0461abffd34f434 128 Gene3D G3DSA:1.20.5.710 3 57 4.2E-19 T 12-10-2018 AFE_0318 f987569a9157bd9ff0461abffd34f434 128 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 128 24.905 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 454 461 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 PIRSF PIRSF000774 1 475 1.4E-150 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 Gene3D G3DSA:1.10.10.1330 119 258 4.5E-25 T 12-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 PRINTS PR00045 Sigma-54 factor signature 375 387 9.7E-32 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 PRINTS PR00045 Sigma-54 factor signature 186 203 9.7E-32 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 PRINTS PR00045 Sigma-54 factor signature 449 467 9.7E-32 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 PRINTS PR00045 Sigma-54 factor signature 391 402 9.7E-32 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 Gene3D G3DSA:1.10.10.60 416 473 1.7E-19 T 12-10-2018 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 363 382 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 49 3.3E-16 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 473 1.1E-156 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 Pfam PF04963 Sigma-54 factor, core binding domain 113 304 4.8E-59 T 12-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 AFE_3025 51edd718a425ed7ff6cf43b9bc8d0b09 475 Pfam PF04552 Sigma-54, DNA binding domain 316 474 3.8E-68 T 12-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 Pfam PF00459 Inositol monophosphatase family 24 254 8.0E-47 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 Gene3D G3DSA:3.40.190.80 151 265 1.2E-21 T 12-10-2018 AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 SUPERFAMILY SSF56655 16 260 3.01E-62 T 12-10-2018 AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 6.2E-25 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 176 197 6.2E-25 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 6.2E-25 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 6.2E-25 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 6.2E-25 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 6.2E-25 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 Gene3D G3DSA:3.30.540.10 10 144 9.4E-35 T 12-10-2018 AFE_3254 ce92dd8229bef63ef8e18c517502de0c 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 210 224 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 AFE_3154 c5a8ac5e382eab50f5dc4ce74ebf23a2 230 Pfam PF03050 Transposase IS66 family 137 208 6.4E-15 T 12-10-2018 IPR004291 Transposase, IS66 AFE_3154 c5a8ac5e382eab50f5dc4ce74ebf23a2 230 Pfam PF13005 zinc-finger binding domain of transposase IS66 84 123 2.3E-15 T 12-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFE_2288 6134ac10c5e6a752df602e110748b7fe 776 Gene3D G3DSA:2.170.130.10 61 188 5.6E-7 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_2288 6134ac10c5e6a752df602e110748b7fe 776 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 759 776 - T 12-10-2018 IPR010917 TonB-dependent receptor, conserved site AFE_2288 6134ac10c5e6a752df602e110748b7fe 776 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 175 3.6E-7 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain AFE_2288 6134ac10c5e6a752df602e110748b7fe 776 SUPERFAMILY SSF56935 63 776 2.17E-52 T 12-10-2018 AFE_2288 6134ac10c5e6a752df602e110748b7fe 776 Gene3D G3DSA:2.40.170.20 189 776 7.5E-35 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily AFE_2090 cd82d82b6a01f32b1a9509c344c29f49 313 Gene3D G3DSA:3.30.2010.10 70 156 3.5E-21 T 12-10-2018 AFE_2090 cd82d82b6a01f32b1a9509c344c29f49 313 Pfam PF01435 Peptidase family M48 79 275 3.6E-30 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFE_1775 fc6d313aa81e830e007c4d97887991d0 477 Pfam PF12626 Polymerase A arginine-rich C-terminus 321 449 9.6E-41 T 12-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain AFE_1775 fc6d313aa81e830e007c4d97887991d0 477 SUPERFAMILY SSF81891 176 414 3.66E-46 T 12-10-2018 AFE_1775 fc6d313aa81e830e007c4d97887991d0 477 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 17 451 1.0E-155 T 12-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 AFE_1775 fc6d313aa81e830e007c4d97887991d0 477 Gene3D G3DSA:3.30.460.10 15 175 1.5E-58 T 12-10-2018 AFE_1775 fc6d313aa81e830e007c4d97887991d0 477 Gene3D G3DSA:1.10.3090.10 177 423 1.4E-84 T 12-10-2018 AFE_1775 fc6d313aa81e830e007c4d97887991d0 477 Pfam PF01743 Poly A polymerase head domain 48 178 1.7E-36 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFE_1775 fc6d313aa81e830e007c4d97887991d0 477 SUPERFAMILY SSF81301 19 174 4.14E-39 T 12-10-2018 AFE_1775 fc6d313aa81e830e007c4d97887991d0 477 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 205 266 1.6E-17 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFE_1775 fc6d313aa81e830e007c4d97887991d0 477 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 2 451 36.951 T 12-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 AFE_0832 e60eae1dab75018fdb1ed5ebfaaabb59 286 SUPERFAMILY SSF53098 174 281 3.41E-15 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_0832 e60eae1dab75018fdb1ed5ebfaaabb59 286 Pfam PF00665 Integrase core domain 180 281 9.1E-13 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFE_0832 e60eae1dab75018fdb1ed5ebfaaabb59 286 Gene3D G3DSA:3.30.420.10 175 282 1.7E-11 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_0506 e60eae1dab75018fdb1ed5ebfaaabb59 286 SUPERFAMILY SSF53098 174 281 3.41E-15 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_0506 e60eae1dab75018fdb1ed5ebfaaabb59 286 Pfam PF00665 Integrase core domain 180 281 9.1E-13 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFE_0506 e60eae1dab75018fdb1ed5ebfaaabb59 286 Gene3D G3DSA:3.30.420.10 175 282 1.7E-11 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_2940 2812eede162dac9823f0142ca3068fb3 244 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 227 244 - T 12-10-2018 IPR010917 TonB-dependent receptor, conserved site AFE_2940 2812eede162dac9823f0142ca3068fb3 244 Pfam PF00593 TonB dependent receptor 9 242 2.8E-19 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_2940 2812eede162dac9823f0142ca3068fb3 244 Gene3D G3DSA:2.40.170.20 2 244 2.0E-29 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily AFE_2940 2812eede162dac9823f0142ca3068fb3 244 SUPERFAMILY SSF56935 9 244 1.03E-23 T 12-10-2018 AFE_2238 8246837784bae906ac2b1dc0033b22a6 176 Pfam PF00696 Amino acid kinase family 25 127 2.4E-10 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFE_2238 8246837784bae906ac2b1dc0033b22a6 176 SUPERFAMILY SSF53633 24 124 2.23E-17 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_2238 8246837784bae906ac2b1dc0033b22a6 176 Gene3D G3DSA:3.40.1160.10 20 128 2.3E-25 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_2238 8246837784bae906ac2b1dc0033b22a6 176 PRINTS PR00474 Glutamate 5-kinase family signature 61 75 1.7E-7 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_2238 8246837784bae906ac2b1dc0033b22a6 176 PRINTS PR00474 Glutamate 5-kinase family signature 95 123 1.7E-7 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_2422 236380e17c4155dcc99c08984e9c2bf0 194 Pfam PF08241 Methyltransferase domain 20 105 1.5E-21 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFE_2422 236380e17c4155dcc99c08984e9c2bf0 194 SUPERFAMILY SSF53335 6 158 1.53E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2422 236380e17c4155dcc99c08984e9c2bf0 194 Gene3D G3DSA:3.40.50.150 2 161 9.1E-34 T 12-10-2018 AFE_2284 ab42541bd8a6ad324e5592119bb1f3e0 378 Pfam PF07969 Amidohydrolase family 318 377 2.8E-8 T 12-10-2018 IPR013108 Amidohydrolase 3 AFE_2284 ab42541bd8a6ad324e5592119bb1f3e0 378 SUPERFAMILY SSF51338 5 377 5.04E-6 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_2284 ab42541bd8a6ad324e5592119bb1f3e0 378 SUPERFAMILY SSF51556 53 344 8.28E-12 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFE_2284 ab42541bd8a6ad324e5592119bb1f3e0 378 PIRSF PIRSF038971 1 378 7.5E-131 T 12-10-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFE_2284 ab42541bd8a6ad324e5592119bb1f3e0 378 Gene3D G3DSA:3.20.20.140 53 170 3.1E-7 T 12-10-2018 AFE_2284 ab42541bd8a6ad324e5592119bb1f3e0 378 TIGRFAM TIGR02318 phosphono_phnM: phosphonate metabolism protein PhnM 6 377 1.1E-120 T 12-10-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFE_2284 ab42541bd8a6ad324e5592119bb1f3e0 378 Gene3D G3DSA:2.30.40.10 315 378 9.4E-6 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_2284 ab42541bd8a6ad324e5592119bb1f3e0 378 Gene3D G3DSA:2.30.40.10 6 52 3.1E-7 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_0142 198fe4814400226a7cee0f505a6b5523 121 SUPERFAMILY SSF52980 8 112 7.24E-19 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFE_0142 198fe4814400226a7cee0f505a6b5523 121 Hamap MF_00048 UPF0102 protein YraN [yraN]. 5 116 22.285 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 AFE_0142 198fe4814400226a7cee0f505a6b5523 121 Gene3D G3DSA:3.40.1350.10 11 120 1.4E-33 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFE_0142 198fe4814400226a7cee0f505a6b5523 121 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 3 117 2.0E-27 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 AFE_0142 198fe4814400226a7cee0f505a6b5523 121 Pfam PF02021 Uncharacterised protein family UPF0102 12 102 2.5E-26 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 SUPERFAMILY SSF51735 4 251 3.31E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.0E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.0E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.0E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.0E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.0E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 Pfam PF00106 short chain dehydrogenase 7 195 1.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3014 c2e0d86f66cbd40f9b5ee930093233d0 257 Gene3D G3DSA:3.40.50.720 3 253 9.9E-49 T 12-10-2018 AFE_0240 3d872076f2e317da4eb3360d1faa2c83 702 Pfam PF03781 Sulfatase-modifying factor enzyme 1 198 447 6.4E-27 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 AFE_0240 3d872076f2e317da4eb3360d1faa2c83 702 SUPERFAMILY SSF56436 197 449 1.39E-53 T 12-10-2018 IPR016187 C-type lectin fold AFE_0240 3d872076f2e317da4eb3360d1faa2c83 702 TIGRFAM TIGR04345 ovoA_Cterm: putative 4-mercaptohistidine N1-methyltranferase 459 701 1.4E-96 T 12-10-2018 IPR027625 Putative 4-mercaptohistidine N1-methyltranferase, OvoA C-terminal domain AFE_0240 3d872076f2e317da4eb3360d1faa2c83 702 Pfam PF13847 Methyltransferase domain 502 635 3.3E-9 T 12-10-2018 IPR025714 Methyltransferase domain AFE_0240 3d872076f2e317da4eb3360d1faa2c83 702 Gene3D G3DSA:3.40.50.150 465 643 1.9E-24 T 12-10-2018 AFE_0240 3d872076f2e317da4eb3360d1faa2c83 702 TIGRFAM TIGR04344 ovoA_Nterm: 5-histidylcysteine sulfoxide synthase 9 447 1.1E-211 T 12-10-2018 IPR027577 5-histidylcysteine sulfoxide synthase AFE_0240 3d872076f2e317da4eb3360d1faa2c83 702 Pfam PF12867 DinB superfamily 27 162 5.3E-8 T 12-10-2018 IPR024775 DinB-like domain AFE_0240 3d872076f2e317da4eb3360d1faa2c83 702 SUPERFAMILY SSF53335 467 663 4.3E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0240 3d872076f2e317da4eb3360d1faa2c83 702 Gene3D G3DSA:3.90.1580.10 193 453 4.8E-23 T 12-10-2018 AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 Gene3D G3DSA:1.25.40.10 26 243 3.2E-42 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 SMART SM00028 168 201 200.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 SMART SM00028 30 63 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 SMART SM00028 134 167 0.14 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 SMART SM00028 202 235 62.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 SMART SM00028 64 97 6.9E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 22 224 2.2E-47 T 12-10-2018 IPR013360 Pilus biogenesis/stability type IV, PilW AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 SUPERFAMILY SSF81901 33 236 4.18E-22 T 12-10-2018 AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 Pfam PF13432 Tetratricopeptide repeat 172 222 3.3E-4 T 12-10-2018 AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 Pfam PF13181 Tetratricopeptide repeat 64 97 9.2E-6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1931 e51bbb8a6284e7aa87246f0abc495928 249 Pfam PF13181 Tetratricopeptide repeat 136 166 0.0027 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 255 3.1E-15 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 97 106 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 Gene3D G3DSA:3.40.120.10 176 361 1.6E-60 T 12-10-2018 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 443 44.969 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 SUPERFAMILY SSF53738 259 364 5.49E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 Gene3D G3DSA:3.40.120.10 258 338 1.6E-60 T 12-10-2018 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 SUPERFAMILY SSF53738 157 257 4.71E-26 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 363 8.1E-31 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 Gene3D G3DSA:3.30.310.50 369 444 2.0E-19 T 12-10-2018 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 438 7.1E-178 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 Gene3D G3DSA:3.40.120.10 2 155 1.3E-49 T 12-10-2018 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 SUPERFAMILY SSF55957 357 440 5.62E-19 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 136 1.1E-44 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 437 1.5E-13 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 SUPERFAMILY SSF53738 2 182 1.18E-49 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 1.0E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 96 110 1.0E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2634 fda18a228de84c57cbc73e529e8cde78 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 1.0E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_1802 7dffa0848c81a9023a0f68e839019a49 306 SUPERFAMILY SSF51569 23 290 1.03E-55 T 12-10-2018 AFE_1802 7dffa0848c81a9023a0f68e839019a49 306 Pfam PF01791 DeoC/LacD family aldolase 35 272 2.3E-41 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFE_1802 7dffa0848c81a9023a0f68e839019a49 306 PIRSF PIRSF038992 13 305 9.4E-59 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFE_1802 7dffa0848c81a9023a0f68e839019a49 306 Gene3D G3DSA:3.20.20.70 3 306 6.1E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1802 7dffa0848c81a9023a0f68e839019a49 306 SMART SM01133 33 273 3.8E-20 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFE_0513 9d6480f9c829cd4dd8cf4909b9b42552 68 Pfam PF10387 Protein of unknown function (DUF2442) 2 59 1.0E-6 T 12-10-2018 IPR018841 Protein of unknown function DUF2442 AFE_0513 9d6480f9c829cd4dd8cf4909b9b42552 68 SUPERFAMILY SSF143880 2 61 1.7E-9 T 12-10-2018 IPR036782 NE0471-like, N-terminal AFE_0667 48085a323d445535ca07a6ffd55afffa 185 Pfam PF04279 Intracellular septation protein A 1 176 1.4E-59 T 12-10-2018 IPR006008 Intracellular septation protein A GO:0016021 AFE_0667 48085a323d445535ca07a6ffd55afffa 185 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 178 2.0E-53 T 12-10-2018 IPR006008 Intracellular septation protein A GO:0016021 AFE_0667 48085a323d445535ca07a6ffd55afffa 185 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 177 18.342 T 12-10-2018 IPR006008 Intracellular septation protein A GO:0016021 AFE_0295 2c09d00990e1efa837135e200b0e2d46 414 PIRSF PIRSF000412 1 414 1.4E-165 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFE_0295 2c09d00990e1efa837135e200b0e2d46 414 SUPERFAMILY SSF53383 6 413 3.89E-175 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_0295 2c09d00990e1efa837135e200b0e2d46 414 Gene3D G3DSA:3.40.640.10 37 287 1.6E-181 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_0295 2c09d00990e1efa837135e200b0e2d46 414 Pfam PF00464 Serine hydroxymethyltransferase 9 381 2.3E-174 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFE_0295 2c09d00990e1efa837135e200b0e2d46 414 Gene3D G3DSA:3.90.1150.10 10 390 1.6E-181 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0295 2c09d00990e1efa837135e200b0e2d46 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 12-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFE_0295 2c09d00990e1efa837135e200b0e2d46 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 414 52.182 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFE_2146 3e24dbb59a1318869cc98ae2553603ae 189 SUPERFAMILY SSF53178 3 187 6.54E-61 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 AFE_2146 3e24dbb59a1318869cc98ae2553603ae 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 180 32.063 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFE_2146 3e24dbb59a1318869cc98ae2553603ae 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 4 171 1.0E-54 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFE_2146 3e24dbb59a1318869cc98ae2553603ae 189 Pfam PF01195 Peptidyl-tRNA hydrolase 4 184 1.9E-49 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFE_2146 3e24dbb59a1318869cc98ae2553603ae 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 109 119 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 AFE_2146 3e24dbb59a1318869cc98ae2553603ae 189 Gene3D G3DSA:3.40.50.1470 2 189 5.5E-60 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 AFE_2644 fe9667e059463bcc49e3731fee70bcfa 250 Pfam PF00753 Metallo-beta-lactamase superfamily 12 175 2.3E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_2644 fe9667e059463bcc49e3731fee70bcfa 250 SUPERFAMILY SSF56281 1 224 6.3E-48 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_2644 fe9667e059463bcc49e3731fee70bcfa 250 Gene3D G3DSA:3.60.15.10 1 237 5.8E-75 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_2644 fe9667e059463bcc49e3731fee70bcfa 250 SMART SM00849 12 175 1.4E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_3169 e830bae3f4b9310026db3512f64d71ed 161 SUPERFAMILY SSF51182 13 148 6.1E-31 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_3169 e830bae3f4b9310026db3512f64d71ed 161 Pfam PF07883 Cupin domain 49 119 1.6E-18 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFE_3169 e830bae3f4b9310026db3512f64d71ed 161 Gene3D G3DSA:2.60.120.10 2 148 1.2E-51 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_2896 1d3b770b177b590cdd8331fc4e6e5b94 686 Pfam PF04932 O-Antigen ligase 207 347 8.3E-17 T 12-10-2018 IPR007016 O-antigen ligase-related AFE_2896 1d3b770b177b590cdd8331fc4e6e5b94 686 Gene3D G3DSA:1.25.40.10 499 685 3.0E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2896 1d3b770b177b590cdd8331fc4e6e5b94 686 SUPERFAMILY SSF48452 499 614 3.59E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 Pfam PF14561 Tetratricopeptide repeat 199 289 6.2E-24 T 12-10-2018 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 Gene3D G3DSA:1.25.40.10 200 289 3.3E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 Gene3D G3DSA:1.25.40.10 115 199 1.7E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 ProSitePatterns PS00194 Thioredoxin family active site. 29 47 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 Pfam PF00085 Thioredoxin 7 110 5.3E-28 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 TIGRFAM TIGR01068 thioredoxin: thioredoxin 13 111 3.8E-29 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 SUPERFAMILY SSF48452 119 259 7.59E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 PRINTS PR00421 Thioredoxin family signature 36 45 3.7E-6 T 12-10-2018 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 PRINTS PR00421 Thioredoxin family signature 76 87 3.7E-6 T 12-10-2018 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 PRINTS PR00421 Thioredoxin family signature 28 36 3.7E-6 T 12-10-2018 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 Pfam PF14559 Tetratricopeptide repeat 126 193 1.9E-11 T 12-10-2018 AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 SUPERFAMILY SSF52833 4 113 3.34E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_2848 bba7caee46ad1722b77baec1f8c06c2d 289 Gene3D G3DSA:3.40.30.10 2 114 8.1E-33 T 12-10-2018 AFE_0445 b99adda5b40cdf73afd196599c14b691 298 Pfam PF00483 Nucleotidyl transferase 11 264 2.0E-27 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFE_0445 b99adda5b40cdf73afd196599c14b691 298 SUPERFAMILY SSF53448 5 277 1.44E-61 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0445 b99adda5b40cdf73afd196599c14b691 298 Gene3D G3DSA:3.90.550.10 1 293 1.4E-85 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0445 b99adda5b40cdf73afd196599c14b691 298 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 265 1.4E-112 T 12-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 AFE_3019 8fdee0ef14eaf81ac465e79d67e3e3e0 90 Gene3D G3DSA:3.30.1340.10 4 89 1.4E-26 T 12-10-2018 IPR035895 HPr-like superfamily AFE_3019 8fdee0ef14eaf81ac465e79d67e3e3e0 90 Pfam PF00381 PTS HPr component phosphorylation site 7 82 7.0E-22 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like AFE_3019 8fdee0ef14eaf81ac465e79d67e3e3e0 90 SUPERFAMILY SSF55594 4 89 2.09E-25 T 12-10-2018 IPR035895 HPr-like superfamily AFE_3019 8fdee0ef14eaf81ac465e79d67e3e3e0 90 PRINTS PR00107 Phosphocarrier protein signature 39 54 1.9E-14 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like AFE_3019 8fdee0ef14eaf81ac465e79d67e3e3e0 90 PRINTS PR00107 Phosphocarrier protein signature 54 71 1.9E-14 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like AFE_3019 8fdee0ef14eaf81ac465e79d67e3e3e0 90 PRINTS PR00107 Phosphocarrier protein signature 14 30 1.9E-14 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like AFE_3019 8fdee0ef14eaf81ac465e79d67e3e3e0 90 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 14 21 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site AFE_3019 8fdee0ef14eaf81ac465e79d67e3e3e0 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 6 81 1.4E-24 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like AFE_3019 8fdee0ef14eaf81ac465e79d67e3e3e0 90 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 40 55 - T 12-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site AFE_2732 1022947ea1b98a7f74ccd2059d76fb37 106 Gene3D G3DSA:4.10.490.10 54 104 4.7E-14 T 12-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 AFE_2732 1022947ea1b98a7f74ccd2059d76fb37 106 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 16 42 1.3E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AFE_2732 1022947ea1b98a7f74ccd2059d76fb37 106 SUPERFAMILY SSF57652 57 104 1.31E-11 T 12-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 AFE_0276 4a986bf22d42fd9912739008c0a7e9df 556 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 66 227 6.4E-17 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFE_2404 92d162833b62b34ef71bc37f4380c590 124 Pfam PF13936 Helix-turn-helix domain 37 80 8.4E-16 T 12-10-2018 IPR025246 Transposase IS30-like HTH domain AFE_3049 9ad19c0ed19af850c11d22e559092fbb 122 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.4E-16 T 12-10-2018 AFE_3049 9ad19c0ed19af850c11d22e559092fbb 122 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.4E-16 T 12-10-2018 AFE_3049 9ad19c0ed19af850c11d22e559092fbb 122 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.4E-16 T 12-10-2018 AFE_3049 9ad19c0ed19af850c11d22e559092fbb 122 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 73 1.6E-18 T 12-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 AFE_3049 9ad19c0ed19af850c11d22e559092fbb 122 Pfam PF02416 mttA/Hcf106 family 5 50 1.3E-7 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AFE_3049 9ad19c0ed19af850c11d22e559092fbb 122 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 121 13.803 T 12-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 AFE_0267 a0e9425468e4b249e5c0412c9724f634 375 Gene3D G3DSA:3.50.50.100 1 375 3.1E-80 T 12-10-2018 AFE_0267 a0e9425468e4b249e5c0412c9724f634 375 SUPERFAMILY SSF51905 4 318 2.42E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0267 a0e9425468e4b249e5c0412c9724f634 375 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 286 4.5E-19 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_0267 a0e9425468e4b249e5c0412c9724f634 375 SUPERFAMILY SSF51905 124 245 4.27E-5 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2763 38fbd641b00ee9af6221ce13ebdaad28 218 SUPERFAMILY SSF89392 32 211 1.1E-32 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFE_2763 38fbd641b00ee9af6221ce13ebdaad28 218 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 19 211 1.4E-22 T 12-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 AFE_2763 38fbd641b00ee9af6221ce13ebdaad28 218 Gene3D G3DSA:2.50.20.10 47 212 3.6E-36 T 12-10-2018 AFE_2763 38fbd641b00ee9af6221ce13ebdaad28 218 Pfam PF03550 Outer membrane lipoprotein LolB 60 210 1.8E-34 T 12-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 AFE_0979 d1f5e8117ec5554cdeb08fa607fb5594 372 Gene3D G3DSA:3.30.1360.120 8 232 7.4E-71 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 AFE_0979 d1f5e8117ec5554cdeb08fa607fb5594 372 Gene3D G3DSA:4.10.1250.10 233 276 2.3E-17 T 12-10-2018 AFE_0979 d1f5e8117ec5554cdeb08fa607fb5594 372 SUPERFAMILY SSF101790 272 360 5.4E-19 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal AFE_0979 d1f5e8117ec5554cdeb08fa607fb5594 372 Gene3D G3DSA:2.40.30.110 280 367 5.0E-19 T 12-10-2018 AFE_0979 d1f5e8117ec5554cdeb08fa607fb5594 372 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 264 353 2.4E-16 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 AFE_0979 d1f5e8117ec5554cdeb08fa607fb5594 372 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 255 5.2E-77 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain AFE_0979 d1f5e8117ec5554cdeb08fa607fb5594 372 Gene3D G3DSA:3.30.70.1400 52 140 7.4E-71 T 12-10-2018 AFE_0979 d1f5e8117ec5554cdeb08fa607fb5594 372 SUPERFAMILY SSF103025 4 278 4.45E-79 T 12-10-2018 AFE_0979 d1f5e8117ec5554cdeb08fa607fb5594 372 PIRSF PIRSF006487 1 365 1.9E-72 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AFE_0979 d1f5e8117ec5554cdeb08fa607fb5594 372 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 359 2.1E-103 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AFE_2948 0d29e130098347e9eeae8dc40bf20045 218 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 10 71 4.8E-11 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFE_2948 0d29e130098347e9eeae8dc40bf20045 218 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 11 215 9.0E-53 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFE_2948 0d29e130098347e9eeae8dc40bf20045 218 SUPERFAMILY SSF52374 9 215 3.1E-54 T 12-10-2018 AFE_2948 0d29e130098347e9eeae8dc40bf20045 218 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 7 216 30.224 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFE_2948 0d29e130098347e9eeae8dc40bf20045 218 Gene3D G3DSA:3.40.50.620 7 216 6.9E-64 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2948 0d29e130098347e9eeae8dc40bf20045 218 Pfam PF01467 Cytidylyltransferase-like 11 188 5.5E-31 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFE_1824 b916cc520744af90d51adbff919fa183 249 SUPERFAMILY SSF103481 137 233 1.19E-8 T 12-10-2018 AFE_1824 b916cc520744af90d51adbff919fa183 249 SUPERFAMILY SSF103481 3 88 1.15E-10 T 12-10-2018 AFE_1824 b916cc520744af90d51adbff919fa183 249 Pfam PF00892 EamA-like transporter family 101 227 3.5E-7 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFE_1824 b916cc520744af90d51adbff919fa183 249 Pfam PF00892 EamA-like transporter family 10 85 1.7E-8 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFE_0212 6631d4fd5bedc501b35bfb19c81fa076 594 Gene3D G3DSA:3.30.450.330 228 555 5.2E-108 T 12-10-2018 AFE_0212 6631d4fd5bedc501b35bfb19c81fa076 594 Gene3D G3DSA:3.90.1310.30 57 227 7.1E-42 T 12-10-2018 AFE_0212 6631d4fd5bedc501b35bfb19c81fa076 594 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 209 2.2E-14 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFE_0212 6631d4fd5bedc501b35bfb19c81fa076 594 Pfam PF00905 Penicillin binding protein transpeptidase domain 252 551 5.4E-73 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFE_0212 6631d4fd5bedc501b35bfb19c81fa076 594 SUPERFAMILY SSF56519 60 226 1.83E-39 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 AFE_0212 6631d4fd5bedc501b35bfb19c81fa076 594 Gene3D G3DSA:3.40.710.10 288 472 5.2E-108 T 12-10-2018 AFE_0212 6631d4fd5bedc501b35bfb19c81fa076 594 SUPERFAMILY SSF56601 179 564 1.11E-92 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_2994 83cb28db4a3f15f33170b73bf8a5780e 647 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 58 213 1.3E-19 T 12-10-2018 IPR024618 Domain of unknown function DUF3857 AFE_2994 83cb28db4a3f15f33170b73bf8a5780e 647 Gene3D G3DSA:2.60.40.3140 48 247 3.2E-18 T 12-10-2018 AFE_2994 83cb28db4a3f15f33170b73bf8a5780e 647 Gene3D G3DSA:2.60.120.1130 558 637 2.2E-6 T 12-10-2018 AFE_2994 83cb28db4a3f15f33170b73bf8a5780e 647 Gene3D G3DSA:3.10.620.30 259 403 1.9E-20 T 12-10-2018 AFE_2994 83cb28db4a3f15f33170b73bf8a5780e 647 Pfam PF12970 Domain of Unknown Function with PDB structure (DUF3858) 560 636 1.7E-8 T 12-10-2018 IPR024544 Domain of unknown function DUF3858 AFE_2685 c941ef1527ed31b3ae5a72a1d32b7fcf 183 Gene3D G3DSA:3.30.1330.60 46 173 9.1E-29 T 12-10-2018 IPR036737 OmpA-like domain superfamily AFE_2685 c941ef1527ed31b3ae5a72a1d32b7fcf 183 Pfam PF00691 OmpA family 73 167 9.2E-19 T 12-10-2018 IPR006665 OmpA-like domain AFE_2685 c941ef1527ed31b3ae5a72a1d32b7fcf 183 PRINTS PR01021 OMPA domain signature 119 135 2.5E-8 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFE_2685 c941ef1527ed31b3ae5a72a1d32b7fcf 183 PRINTS PR01021 OMPA domain signature 74 96 2.5E-8 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFE_2685 c941ef1527ed31b3ae5a72a1d32b7fcf 183 PRINTS PR01021 OMPA domain signature 104 119 2.5E-8 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFE_2685 c941ef1527ed31b3ae5a72a1d32b7fcf 183 SUPERFAMILY SSF103088 46 172 1.44E-29 T 12-10-2018 IPR036737 OmpA-like domain superfamily AFE_0299 35b6071025c00eb1a608edc677b048bc 377 SUPERFAMILY SSF55821 5 205 5.95E-85 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFE_0299 35b6071025c00eb1a608edc677b048bc 377 Pfam PF00925 GTP cyclohydrolase II 215 367 4.3E-26 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFE_0299 35b6071025c00eb1a608edc677b048bc 377 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 4 206 38.063 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0299 35b6071025c00eb1a608edc677b048bc 377 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 8 202 1.7E-71 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0299 35b6071025c00eb1a608edc677b048bc 377 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 10 201 2.5E-83 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_0299 35b6071025c00eb1a608edc677b048bc 377 Gene3D G3DSA:3.90.870.10 1 209 4.0E-88 T 12-10-2018 AFE_0299 35b6071025c00eb1a608edc677b048bc 377 SUPERFAMILY SSF142695 208 369 2.22E-35 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFE_0299 35b6071025c00eb1a608edc677b048bc 377 PIRSF PIRSF001259 4 377 1.2E-116 T 12-10-2018 AFE_0583 2128c86876078a5bb78d6fa67cab35de 76 Pfam PF14076 Domain of unknown function (DUF4258) 5 69 1.2E-12 T 12-10-2018 IPR025354 Protein of unknown function DUF4258 AFE_0899 71da9b65e0e9bf890de2ace78d685520 338 SUPERFAMILY SSF51569 1 336 6.96E-113 T 12-10-2018 AFE_0899 71da9b65e0e9bf890de2ace78d685520 338 Gene3D G3DSA:3.20.20.70 76 333 2.9E-99 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_0899 71da9b65e0e9bf890de2ace78d685520 338 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 71 328 7.3E-110 T 12-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AFE_0899 71da9b65e0e9bf890de2ace78d685520 338 Gene3D G3DSA:3.30.70.1140 1 75 1.1E-27 T 12-10-2018 AFE_0899 71da9b65e0e9bf890de2ace78d685520 338 Pfam PF00793 DAHP synthetase I family 88 323 3.0E-69 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFE_0746 9aae6341b50d4011e715a32122f5e6dd 161 Pfam PF13710 ACT domain 13 73 1.1E-14 T 12-10-2018 AFE_0746 9aae6341b50d4011e715a32122f5e6dd 161 Gene3D G3DSA:3.30.70.260 1 78 1.4E-33 T 12-10-2018 AFE_0746 9aae6341b50d4011e715a32122f5e6dd 161 SUPERFAMILY SSF55021 1 76 6.87E-23 T 12-10-2018 AFE_0746 9aae6341b50d4011e715a32122f5e6dd 161 SUPERFAMILY SSF55021 79 160 7.32E-25 T 12-10-2018 AFE_0746 9aae6341b50d4011e715a32122f5e6dd 161 Pfam PF10369 Small subunit of acetolactate synthase 84 157 1.4E-26 T 12-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFE_0746 9aae6341b50d4011e715a32122f5e6dd 161 Gene3D G3DSA:3.30.70.1150 83 161 1.3E-28 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal AFE_0746 9aae6341b50d4011e715a32122f5e6dd 161 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 5.3E-63 T 12-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFE_0746 9aae6341b50d4011e715a32122f5e6dd 161 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-30 T 12-10-2018 AFE_2561 d6f39b4deeb43e1de312ef412dd71a15 169 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 8 154 2.0E-58 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2561 d6f39b4deeb43e1de312ef412dd71a15 169 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 5 161 32.717 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2561 d6f39b4deeb43e1de312ef412dd71a15 169 SUPERFAMILY SSF55040 14 158 2.35E-56 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2561 d6f39b4deeb43e1de312ef412dd71a15 169 Gene3D G3DSA:3.30.70.640 5 162 3.5E-61 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2561 d6f39b4deeb43e1de312ef412dd71a15 169 Pfam PF01967 MoaC family 18 153 1.0E-50 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_1971 cd0ed761a077ef03282cb672a4c66e5b 387 Pfam PF12832 MFS_1 like family 9 359 6.5E-66 T 12-10-2018 IPR024989 Major facilitator superfamily associated domain AFE_1971 cd0ed761a077ef03282cb672a4c66e5b 387 Gene3D G3DSA:1.20.1250.20 8 180 1.6E-21 T 12-10-2018 AFE_1971 cd0ed761a077ef03282cb672a4c66e5b 387 Gene3D G3DSA:1.20.1250.20 192 384 3.7E-40 T 12-10-2018 AFE_1971 cd0ed761a077ef03282cb672a4c66e5b 387 SUPERFAMILY SSF103473 9 380 1.16E-42 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_1971 cd0ed761a077ef03282cb672a4c66e5b 387 PIRSF PIRSF004925 2 386 4.8E-98 T 12-10-2018 IPR026032 Probable 3-phenylpropionic acid transporter AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 SMART SM00997 193 377 7.0E-77 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 SMART SM00996 7 464 2.5E-276 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 Gene3D G3DSA:3.40.50.1480 145 199 1.7E-19 T 12-10-2018 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 Gene3D G3DSA:3.40.50.1480 375 465 5.4E-30 T 12-10-2018 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 193 377 1.7E-54 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 79 93 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 3 457 44.334 T 12-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 SUPERFAMILY SSF52283 6 465 1.19E-109 T 12-10-2018 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 PIRSF PIRSF001109 2 465 4.7E-180 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 8 457 2.4E-157 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 215 232 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 Gene3D G3DSA:3.40.50.1480 1 144 2.4E-72 T 12-10-2018 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 7 143 3.4E-74 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 SUPERFAMILY SSF51735 193 378 4.83E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0534 1950672139eccafb43a153f5e6ba3e20 465 Gene3D G3DSA:3.40.50.720 200 374 3.0E-67 T 12-10-2018 AFE_1797 e112ababbd178d31c552bf8c13c9aedb 503 SUPERFAMILY SSF103473 12 499 5.23E-68 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_1797 e112ababbd178d31c552bf8c13c9aedb 503 Pfam PF07690 Major Facilitator Superfamily 23 416 1.0E-59 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_1797 e112ababbd178d31c552bf8c13c9aedb 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 1.3E-5 T 12-10-2018 AFE_1797 e112ababbd178d31c552bf8c13c9aedb 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 1.3E-5 T 12-10-2018 AFE_1797 e112ababbd178d31c552bf8c13c9aedb 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 112 132 1.3E-5 T 12-10-2018 AFE_1797 e112ababbd178d31c552bf8c13c9aedb 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 407 426 1.3E-5 T 12-10-2018 AFE_1797 e112ababbd178d31c552bf8c13c9aedb 503 Gene3D G3DSA:1.20.1250.20 265 503 8.3E-17 T 12-10-2018 AFE_1797 e112ababbd178d31c552bf8c13c9aedb 503 Gene3D G3DSA:1.20.1720.10 18 226 2.1E-52 T 12-10-2018 AFE_1797 e112ababbd178d31c552bf8c13c9aedb 503 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 495 2.6E-122 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFE_2448 f2e91a39a00027fb65e2dd062aae2c68 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFE_2448 f2e91a39a00027fb65e2dd062aae2c68 68 Gene3D G3DSA:3.30.70.100 4 67 4.8E-23 T 12-10-2018 AFE_2448 f2e91a39a00027fb65e2dd062aae2c68 68 SUPERFAMILY SSF55008 3 66 1.96E-18 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFE_2448 f2e91a39a00027fb65e2dd062aae2c68 68 Pfam PF00403 Heavy-metal-associated domain 6 63 3.3E-15 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFE_2250 a1065710011404159359da9605ff07ec 373 Gene3D G3DSA:2.40.160.180 33 372 3.5E-40 T 12-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily AFE_2250 a1065710011404159359da9605ff07ec 373 Pfam PF04966 Carbohydrate-selective porin, OprB family 79 372 2.3E-15 T 12-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 AFE_2188 e5c684e9a9131464d7ca9d1ae5c32b15 91 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.297 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2188 e5c684e9a9131464d7ca9d1ae5c32b15 91 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 90 1.0E-17 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2188 e5c684e9a9131464d7ca9d1ae5c32b15 91 SUPERFAMILY SSF46992 3 86 6.8E-29 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2188 e5c684e9a9131464d7ca9d1ae5c32b15 91 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 6.5E-25 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2188 e5c684e9a9131464d7ca9d1ae5c32b15 91 Pfam PF01649 Ribosomal protein S20 2 84 1.0E-26 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2188 e5c684e9a9131464d7ca9d1ae5c32b15 91 Gene3D G3DSA:1.20.58.110 1 87 9.0E-28 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_3248 b37e123aa570f71fcf9c07ba4b6af39d 356 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 6.6E-197 T 12-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AFE_3248 b37e123aa570f71fcf9c07ba4b6af39d 356 Gene3D G3DSA:3.20.20.70 1 354 4.0E-153 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_3248 b37e123aa570f71fcf9c07ba4b6af39d 356 PIRSF PIRSF001359 1 329 1.9E-84 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFE_3248 b37e123aa570f71fcf9c07ba4b6af39d 356 SUPERFAMILY SSF51569 1 329 4.25E-107 T 12-10-2018 AFE_3248 b37e123aa570f71fcf9c07ba4b6af39d 356 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 2.6E-98 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFE_3248 b37e123aa570f71fcf9c07ba4b6af39d 356 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFE_3248 b37e123aa570f71fcf9c07ba4b6af39d 356 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFE_3248 b37e123aa570f71fcf9c07ba4b6af39d 356 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 328 8.0E-94 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFE_2769 d1b567d0305a6ace1a3453218ecd30b4 440 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 402 433 9.5E-8 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFE_2769 d1b567d0305a6ace1a3453218ecd30b4 440 SUPERFAMILY SSF52980 272 379 1.77E-20 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFE_2769 d1b567d0305a6ace1a3453218ecd30b4 440 Gene3D G3DSA:3.40.1350.10 273 380 5.9E-5 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFE_2769 d1b567d0305a6ace1a3453218ecd30b4 440 Pfam PF04471 Restriction endonuclease 267 377 8.7E-29 T 12-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AFE_2769 d1b567d0305a6ace1a3453218ecd30b4 440 SUPERFAMILY SSF57783 399 432 5.78E-6 T 12-10-2018 AFE_2769 d1b567d0305a6ace1a3453218ecd30b4 440 Gene3D G3DSA:3.30.65.10 393 435 3.7E-6 T 12-10-2018 AFE_2277 c590efb3f29b2f9451193fd8dcf0abd7 465 ProSitePatterns PS00217 Sugar transport proteins signature 2. 116 141 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFE_2277 c590efb3f29b2f9451193fd8dcf0abd7 465 Gene3D G3DSA:1.20.1250.20 12 452 1.5E-89 T 12-10-2018 AFE_2277 c590efb3f29b2f9451193fd8dcf0abd7 465 Pfam PF00083 Sugar (and other) transporter 23 435 5.1E-53 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFE_2277 c590efb3f29b2f9451193fd8dcf0abd7 465 SUPERFAMILY SSF103473 9 448 1.57E-75 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_2277 c590efb3f29b2f9451193fd8dcf0abd7 465 PRINTS PR00171 Sugar transporter signature 28 38 3.1E-5 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_2277 c590efb3f29b2f9451193fd8dcf0abd7 465 PRINTS PR00171 Sugar transporter signature 375 387 3.1E-5 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_2277 c590efb3f29b2f9451193fd8dcf0abd7 465 PRINTS PR00171 Sugar transporter signature 352 373 3.1E-5 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_2277 c590efb3f29b2f9451193fd8dcf0abd7 465 PRINTS PR00171 Sugar transporter signature 111 130 3.1E-5 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_2277 c590efb3f29b2f9451193fd8dcf0abd7 465 ProSitePatterns PS01159 WW/rsp5/WWP domain signature. 349 374 - T 12-10-2018 IPR001202 WW domain GO:0005515 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 288 342 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 510 2.2E-121 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 SUPERFAMILY SSF81442 43 565 4.19E-151 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 174 186 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 286 307 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 105 128 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 356 377 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 132 156 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 206 224 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 332 347 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 419 438 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 391 409 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 235 254 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 PRINTS PR01165 Cytochrome c oxidase subunit I signature 468 489 2.9E-76 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0632 36d936abe1f1ea883f14b873868b6e84 705 Gene3D G3DSA:1.20.210.10 43 568 3.0E-161 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_2192 1c1518c4295a5a03e989d6e3aec09761 145 Pfam PF02635 DsrE/DsrF-like family 45 142 2.6E-5 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFE_2192 1c1518c4295a5a03e989d6e3aec09761 145 Gene3D G3DSA:3.40.1260.10 32 144 4.1E-12 T 12-10-2018 IPR027396 DsrEFH-like AFE_2192 1c1518c4295a5a03e989d6e3aec09761 145 SUPERFAMILY SSF75169 44 140 1.84E-8 T 12-10-2018 IPR027396 DsrEFH-like AFE_2610 906d30c51b740d12e8906759f23eb476 340 SUPERFAMILY SSF55681 93 339 5.69E-75 T 12-10-2018 AFE_2610 906d30c51b740d12e8906759f23eb476 340 Pfam PF01409 tRNA synthetases class II core domain (F) 93 339 3.6E-98 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 AFE_2610 906d30c51b740d12e8906759f23eb476 340 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 88 2.2E-23 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFE_2610 906d30c51b740d12e8906759f23eb476 340 SUPERFAMILY SSF46589 15 100 2.56E-21 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AFE_2610 906d30c51b740d12e8906759f23eb476 340 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 339 48.212 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 AFE_2610 906d30c51b740d12e8906759f23eb476 340 Gene3D G3DSA:3.30.930.10 9 340 1.8E-117 T 12-10-2018 AFE_2610 906d30c51b740d12e8906759f23eb476 340 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 339 7.7E-102 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 PIRSF PIRSF039102 45 308 4.7E-79 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 PIRSF PIRSF039102 2 55 1.1E-7 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 SUPERFAMILY SSF56059 99 298 2.41E-51 T 12-10-2018 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 Pfam PF07478 D-ala D-ala ligase C-terminus 106 298 3.6E-46 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 66 77 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 5 302 32.988 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 244 272 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 SUPERFAMILY SSF52440 6 99 1.44E-25 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 301 2.4E-89 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 Pfam PF01820 D-ala D-ala ligase N-terminus 6 89 1.0E-16 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 Gene3D G3DSA:3.30.1490.20 114 179 2.3E-68 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 Gene3D G3DSA:3.40.50.20 1 87 2.6E-25 T 12-10-2018 AFE_0203 9f0c1e3e0d0d332369ebb6c606879a9b 308 Gene3D G3DSA:3.30.470.20 88 298 2.3E-68 T 12-10-2018 AFE_0784 172cddbc1169f8a098c53330a367222e 202 SUPERFAMILY SSF53448 3 150 1.31E-17 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0784 172cddbc1169f8a098c53330a367222e 202 Pfam PF12804 MobA-like NTP transferase domain 4 156 1.3E-22 T 12-10-2018 IPR025877 MobA-like NTP transferase AFE_0784 172cddbc1169f8a098c53330a367222e 202 Gene3D G3DSA:3.90.550.10 3 194 3.4E-23 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_1430 5c04e2140fdf84dd2b5e357f19e3b28c 322 Pfam PF01545 Cation efflux family 40 225 4.3E-39 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFE_1430 5c04e2140fdf84dd2b5e357f19e3b28c 322 SUPERFAMILY SSF160240 233 306 3.79E-9 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFE_1430 5c04e2140fdf84dd2b5e357f19e3b28c 322 Gene3D G3DSA:1.20.1510.10 34 227 9.9E-37 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFE_1430 5c04e2140fdf84dd2b5e357f19e3b28c 322 SUPERFAMILY SSF161111 35 228 1.2E-48 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFE_1430 5c04e2140fdf84dd2b5e357f19e3b28c 322 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 36 307 1.1E-72 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFE_1875 fc4df04f5f8b7fc02fd272eb8778ba3d 212 Gene3D G3DSA:3.40.50.300 4 206 6.9E-37 T 12-10-2018 AFE_1875 fc4df04f5f8b7fc02fd272eb8778ba3d 212 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 175 8.9E-16 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFE_1875 fc4df04f5f8b7fc02fd272eb8778ba3d 212 SUPERFAMILY SSF52540 3 185 3.18E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1201 552cd9802ac7af21c75e595fe56c0594 276 Gene3D G3DSA:3.40.1350.10 7 169 6.5E-69 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFE_1201 552cd9802ac7af21c75e595fe56c0594 276 Pfam PF08722 TnsA endonuclease N terminal 74 166 1.5E-26 T 12-10-2018 IPR014833 TnsA endonuclease, N-terminal AFE_1201 552cd9802ac7af21c75e595fe56c0594 276 SUPERFAMILY SSF52980 9 169 2.9E-64 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFE_1201 552cd9802ac7af21c75e595fe56c0594 276 Pfam PF08721 TnsA endonuclease C terminal 168 251 2.8E-21 T 12-10-2018 IPR014832 TnsA endonuclease C-terminal AFE_1201 552cd9802ac7af21c75e595fe56c0594 276 Gene3D G3DSA:1.10.10.10 171 258 2.3E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2217 b6361e37502afa22382f58639053f663 297 SUPERFAMILY SSF53474 6 283 4.8E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_2217 b6361e37502afa22382f58639053f663 297 Pfam PF12697 Alpha/beta hydrolase family 27 281 1.1E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFE_2217 b6361e37502afa22382f58639053f663 297 Gene3D G3DSA:3.40.50.1820 1 284 3.5E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_2791 3e96089c22dd758ccda3995cd38a458a 418 SUPERFAMILY SSF116734 198 402 6.05E-27 T 12-10-2018 AFE_2791 3e96089c22dd758ccda3995cd38a458a 418 Pfam PF01420 Type I restriction modification DNA specificity domain 4 157 8.7E-14 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFE_2791 3e96089c22dd758ccda3995cd38a458a 418 Pfam PF01420 Type I restriction modification DNA specificity domain 213 355 7.6E-6 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFE_2791 3e96089c22dd758ccda3995cd38a458a 418 Gene3D G3DSA:3.90.220.20 200 400 3.1E-21 T 12-10-2018 AFE_2791 3e96089c22dd758ccda3995cd38a458a 418 Gene3D G3DSA:3.90.220.20 1 126 8.4E-21 T 12-10-2018 AFE_2791 3e96089c22dd758ccda3995cd38a458a 418 SUPERFAMILY SSF116734 2 171 5.89E-38 T 12-10-2018 AFE_2782 a9f250030e970ca4ebbc81cc00712b48 120 Pfam PF11604 Copper binding periplasmic protein CusF 50 116 3.3E-19 T 12-10-2018 IPR021647 Copper binding periplasmic protein CusF AFE_2782 a9f250030e970ca4ebbc81cc00712b48 120 Gene3D G3DSA:2.40.50.320 44 117 2.3E-16 T 12-10-2018 AFE_2253 e9982c3eeadd164613d6271fc3c25146 1569 Pfam PF00207 Alpha-2-macroglobulin family 910 986 9.9E-5 T 12-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 AFE_2253 e9982c3eeadd164613d6271fc3c25146 1569 Pfam PF07678 A-macroglobulin complement component 1154 1211 3.6E-6 T 12-10-2018 IPR011626 Alpha-macroglobulin complement component GO:0005615 AFE_2253 e9982c3eeadd164613d6271fc3c25146 1569 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 250 350 6.0E-13 T 12-10-2018 AFE_2253 e9982c3eeadd164613d6271fc3c25146 1569 SMART SM01360 908 997 4.5E-14 T 12-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 AFE_2253 e9982c3eeadd164613d6271fc3c25146 1569 PIRSF PIRSF038980 4 1568 3.8E-300 T 12-10-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria AFE_2253 e9982c3eeadd164613d6271fc3c25146 1569 Gene3D G3DSA:1.50.10.20 1100 1346 2.5E-17 T 12-10-2018 AFE_2253 e9982c3eeadd164613d6271fc3c25146 1569 SUPERFAMILY SSF48239 1140 1353 1.71E-24 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AFE_2253 e9982c3eeadd164613d6271fc3c25146 1569 Pfam PF01835 MG2 domain 358 450 2.5E-15 T 12-10-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 AFE_2253 e9982c3eeadd164613d6271fc3c25146 1569 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 716 848 1.0E-14 T 12-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 AFE_2253 e9982c3eeadd164613d6271fc3c25146 1569 SMART SM01359 711 848 1.2E-30 T 12-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 AFE_0462 b5cbe7f0a5dcc9126457d1f3b8fe17a3 263 Gene3D G3DSA:3.30.1380.10 45 242 4.7E-41 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFE_0462 b5cbe7f0a5dcc9126457d1f3b8fe17a3 263 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 23 245 25.641 T 12-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 AFE_0462 b5cbe7f0a5dcc9126457d1f3b8fe17a3 263 Pfam PF01427 D-ala-D-ala dipeptidase 54 245 2.6E-33 T 12-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 AFE_0462 b5cbe7f0a5dcc9126457d1f3b8fe17a3 263 PIRSF PIRSF026671 3 251 4.8E-45 T 12-10-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 AFE_0462 b5cbe7f0a5dcc9126457d1f3b8fe17a3 263 SUPERFAMILY SSF55166 24 242 2.88E-46 T 12-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFE_0435 f75fb3e48a5a6d867fa9f03598d6b790 217 SUPERFAMILY SSF56784 1 205 1.11E-33 T 12-10-2018 IPR036412 HAD-like superfamily AFE_0435 f75fb3e48a5a6d867fa9f03598d6b790 217 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 167 9.8E-13 T 12-10-2018 AFE_0435 f75fb3e48a5a6d867fa9f03598d6b790 217 Gene3D G3DSA:3.90.1470.20 14 133 6.4E-40 T 12-10-2018 AFE_0435 f75fb3e48a5a6d867fa9f03598d6b790 217 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 169 1.3E-17 T 12-10-2018 AFE_0435 f75fb3e48a5a6d867fa9f03598d6b790 217 Gene3D G3DSA:3.40.50.1000 5 200 6.4E-40 T 12-10-2018 IPR023214 HAD superfamily AFE_0981 c0552a309eedc1d0a20c75482005b1ac 447 Gene3D G3DSA:3.90.1150.10 67 436 3.1E-133 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0981 c0552a309eedc1d0a20c75482005b1ac 447 SUPERFAMILY SSF53383 1 444 3.17E-95 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_0981 c0552a309eedc1d0a20c75482005b1ac 447 Pfam PF02347 Glycine cleavage system P-protein 3 389 1.2E-102 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AFE_0981 c0552a309eedc1d0a20c75482005b1ac 447 Gene3D G3DSA:3.40.640.10 78 345 3.1E-133 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 Gene3D G3DSA:1.10.1040.10 186 333 9.1E-48 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 Gene3D G3DSA:3.40.50.720 1 185 5.5E-41 T 12-10-2018 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 319 34.331 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 177 316 8.7E-46 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 PIRSF PIRSF000114 1 329 1.8E-85 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 170 194 4.5E-35 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 5 22 4.5E-35 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 55 82 4.5E-35 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 195 219 4.5E-35 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 130 150 4.5E-35 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 235 252 4.5E-35 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 SUPERFAMILY SSF48179 176 328 3.57E-50 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 SUPERFAMILY SSF51735 4 177 1.18E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2126 73910f47f6eec8fc695941a20e8cd0a7 344 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 156 5.1E-31 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFE_2471 2333d95e1c3382a626732129c67951ec 192 Gene3D G3DSA:4.10.520.10 106 192 1.7E-17 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_2471 2333d95e1c3382a626732129c67951ec 192 Pfam PF00216 Bacterial DNA-binding protein 122 191 2.0E-17 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_2471 2333d95e1c3382a626732129c67951ec 192 SMART SM00411 103 191 2.5E-6 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_2471 2333d95e1c3382a626732129c67951ec 192 SUPERFAMILY SSF47729 120 191 8.24E-16 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_1476 a572680ba9e3063764972985358f9e48 164 SUPERFAMILY SSF48452 40 147 2.89E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1476 a572680ba9e3063764972985358f9e48 164 Gene3D G3DSA:1.25.40.10 16 161 5.1E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1665 a8b330dc9c1fc3ece78b62be80604044 488 SUPERFAMILY SSF55103 193 462 8.34E-72 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFE_1665 a8b330dc9c1fc3ece78b62be80604044 488 Pfam PF01565 FAD binding domain 45 183 2.2E-38 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFE_1665 a8b330dc9c1fc3ece78b62be80604044 488 Pfam PF02913 FAD linked oxidases, C-terminal domain 220 459 9.8E-68 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFE_1665 a8b330dc9c1fc3ece78b62be80604044 488 Gene3D G3DSA:3.30.465.40 8 238 1.7E-61 T 12-10-2018 AFE_1665 a8b330dc9c1fc3ece78b62be80604044 488 Gene3D G3DSA:3.30.70.2740 339 420 3.8E-9 T 12-10-2018 AFE_1665 a8b330dc9c1fc3ece78b62be80604044 488 SUPERFAMILY SSF56176 9 220 2.01E-67 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFE_1665 a8b330dc9c1fc3ece78b62be80604044 488 Gene3D G3DSA:1.10.45.10 421 461 1.7E-8 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFE_1521 14ddd2baf05e6f252931d95fb01a5806 491 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 71 478 8.1E-108 T 12-10-2018 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 AFE_1521 14ddd2baf05e6f252931d95fb01a5806 491 TIGRFAM TIGR01862 N2-ase-Ialpha: nitrogenase component I, alpha chain 39 484 1.0E-187 T 12-10-2018 IPR010143 Nitrogenase component 1, alpha chain GO:0009399|GO:0016163|GO:0051536|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 AFE_1521 14ddd2baf05e6f252931d95fb01a5806 491 Gene3D G3DSA:3.40.50.1980 38 485 4.3E-216 T 12-10-2018 AFE_1521 14ddd2baf05e6f252931d95fb01a5806 491 TIGRFAM TIGR01282 nifD: nitrogenase molybdenum-iron protein alpha chain 23 490 1.9E-263 T 12-10-2018 IPR005972 Nitrogenase molybdenum-iron protein alpha chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 AFE_1521 14ddd2baf05e6f252931d95fb01a5806 491 Gene3D G3DSA:3.40.50.1980 216 356 4.3E-216 T 12-10-2018 AFE_1521 14ddd2baf05e6f252931d95fb01a5806 491 Gene3D G3DSA:3.40.50.1980 72 215 4.3E-216 T 12-10-2018 AFE_1521 14ddd2baf05e6f252931d95fb01a5806 491 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 161 175 - T 12-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 AFE_1521 14ddd2baf05e6f252931d95fb01a5806 491 SUPERFAMILY SSF53807 35 490 2.55E-160 T 12-10-2018 AFE_1521 14ddd2baf05e6f252931d95fb01a5806 491 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 90 97 - T 12-10-2018 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 AFE_2618 397248089e26cb1d323b952e65fb3047 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 167 191 3.6E-47 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2618 397248089e26cb1d323b952e65fb3047 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 3.6E-47 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2618 397248089e26cb1d323b952e65fb3047 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 325 344 3.6E-47 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2618 397248089e26cb1d323b952e65fb3047 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 377 403 3.6E-47 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2618 397248089e26cb1d323b952e65fb3047 494 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 137 156 3.6E-47 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2618 397248089e26cb1d323b952e65fb3047 494 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 487 3.0E-195 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2618 397248089e26cb1d323b952e65fb3047 494 Pfam PF00361 Proton-conducting membrane transporter 131 418 6.6E-82 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_3274 12e9a3da10e51e2fabb93c5dc69a4236 245 Gene3D G3DSA:1.10.10.10 132 237 2.7E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_3274 12e9a3da10e51e2fabb93c5dc69a4236 245 SMART SM00448 5 116 3.7E-44 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_3274 12e9a3da10e51e2fabb93c5dc69a4236 245 SUPERFAMILY SSF46894 127 233 3.4E-25 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFE_3274 12e9a3da10e51e2fabb93c5dc69a4236 245 SMART SM00862 154 231 8.1E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_3274 12e9a3da10e51e2fabb93c5dc69a4236 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 1.5E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_3274 12e9a3da10e51e2fabb93c5dc69a4236 245 Pfam PF00072 Response regulator receiver domain 7 117 1.2E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_3274 12e9a3da10e51e2fabb93c5dc69a4236 245 SUPERFAMILY SSF52172 3 128 9.25E-44 T 12-10-2018 IPR011006 CheY-like superfamily AFE_3274 12e9a3da10e51e2fabb93c5dc69a4236 245 Gene3D G3DSA:3.40.50.2300 5 131 8.3E-40 T 12-10-2018 AFE_1093 ce1d3e0d2163447598b84d8125e5c5bb 322 Gene3D G3DSA:2.60.120.260 170 311 2.9E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFE_1663 396abfb17b82dbff511b3b4f5db064bc 416 Pfam PF12838 4Fe-4S dicluster domain 24 89 3.5E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_1663 396abfb17b82dbff511b3b4f5db064bc 416 Pfam PF02754 Cysteine-rich domain 305 389 2.1E-12 T 12-10-2018 IPR004017 Cysteine-rich domain AFE_1663 396abfb17b82dbff511b3b4f5db064bc 416 Pfam PF02754 Cysteine-rich domain 176 257 9.6E-11 T 12-10-2018 IPR004017 Cysteine-rich domain AFE_1663 396abfb17b82dbff511b3b4f5db064bc 416 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_1663 396abfb17b82dbff511b3b4f5db064bc 416 SUPERFAMILY SSF54862 7 115 1.26E-19 T 12-10-2018 AFE_1663 396abfb17b82dbff511b3b4f5db064bc 416 Gene3D G3DSA:1.10.1060.10 5 106 5.1E-8 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_1663 396abfb17b82dbff511b3b4f5db064bc 416 PIRSF PIRSF000139 5 412 5.3E-116 T 12-10-2018 AFE_2523 ae6e54fca53511bf3a4d3164afcf0eec 95 SMART SM00899 12 83 2.1E-4 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AFE_2523 ae6e54fca53511bf3a4d3164afcf0eec 95 SUPERFAMILY SSF50037 16 82 7.02E-8 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal AFE_2523 ae6e54fca53511bf3a4d3164afcf0eec 95 Pfam PF04023 FeoA domain 15 81 6.1E-10 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AFE_2523 ae6e54fca53511bf3a4d3164afcf0eec 95 Gene3D G3DSA:2.30.30.90 14 91 1.8E-11 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain AFE_0355 d9af19febea538fcf77d55cbe1a25970 124 Pfam PF01196 Ribosomal protein L17 20 116 9.4E-33 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0355 d9af19febea538fcf77d55cbe1a25970 124 Gene3D G3DSA:3.90.1030.10 1 117 3.1E-46 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0355 d9af19febea538fcf77d55cbe1a25970 124 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 7.7E-42 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0355 d9af19febea538fcf77d55cbe1a25970 124 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0355 d9af19febea538fcf77d55cbe1a25970 124 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.467 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0355 d9af19febea538fcf77d55cbe1a25970 124 SUPERFAMILY SSF64263 1 118 3.4E-47 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_3288 6bae2275317b008c975f4ac3622e4f56 266 PIRSF PIRSF005624 39 265 5.4E-96 T 12-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 AFE_3288 6bae2275317b008c975f4ac3622e4f56 266 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 48 256 7.4E-89 T 12-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 AFE_3288 6bae2275317b008c975f4ac3622e4f56 266 SUPERFAMILY SSF52540 50 256 1.56E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3288 6bae2275317b008c975f4ac3622e4f56 266 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 76 238 4.4E-36 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFE_3288 6bae2275317b008c975f4ac3622e4f56 266 Gene3D G3DSA:3.40.50.300 56 260 1.0E-62 T 12-10-2018 AFE_3137 a4d896850de53db5bb514b7cc193f39c 171 Pfam PF00072 Response regulator receiver domain 1 109 1.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_3137 a4d896850de53db5bb514b7cc193f39c 171 SMART SM00448 1 109 1.4E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_3137 a4d896850de53db5bb514b7cc193f39c 171 Gene3D G3DSA:1.10.10.60 112 170 1.6E-23 T 12-10-2018 AFE_3137 a4d896850de53db5bb514b7cc193f39c 171 SUPERFAMILY SSF52172 1 114 1.25E-32 T 12-10-2018 IPR011006 CheY-like superfamily AFE_3137 a4d896850de53db5bb514b7cc193f39c 171 Gene3D G3DSA:3.40.50.2300 1 111 1.3E-29 T 12-10-2018 AFE_3137 a4d896850de53db5bb514b7cc193f39c 171 Pfam PF02954 Bacterial regulatory protein, Fis family 128 167 3.6E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_3137 a4d896850de53db5bb514b7cc193f39c 171 SUPERFAMILY SSF46689 95 168 9.86E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_3137 a4d896850de53db5bb514b7cc193f39c 171 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 133 150 8.2E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_3137 a4d896850de53db5bb514b7cc193f39c 171 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 150 170 8.2E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_3189 7aece88c109eb92fdd5d04a167c7512f 287 SUPERFAMILY SSF52540 8 244 3.96E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3189 7aece88c109eb92fdd5d04a167c7512f 287 Gene3D G3DSA:3.40.50.300 8 210 6.4E-22 T 12-10-2018 AFE_2979 30959843c3e169036bcddcd048d707da 272 Gene3D G3DSA:3.40.50.150 1 224 4.2E-51 T 12-10-2018 AFE_2979 30959843c3e169036bcddcd048d707da 272 Pfam PF13649 Methyltransferase domain 44 134 1.2E-12 T 12-10-2018 AFE_2979 30959843c3e169036bcddcd048d707da 272 SUPERFAMILY SSF53335 6 187 1.4E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_1953 5654534fb559372ed0df1e69e15a37dc 71 Gene3D G3DSA:3.30.70.20 2 67 9.8E-22 T 12-10-2018 AFE_1953 5654534fb559372ed0df1e69e15a37dc 71 SUPERFAMILY SSF54862 4 63 1.77E-15 T 12-10-2018 AFE_1953 5654534fb559372ed0df1e69e15a37dc 71 Pfam PF12838 4Fe-4S dicluster domain 9 57 8.4E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_1953 5654534fb559372ed0df1e69e15a37dc 71 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_0821 13b3efa89ea615242e138a4e2d3289e5 158 Gene3D G3DSA:3.60.21.10 1 129 3.3E-8 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFE_0821 13b3efa89ea615242e138a4e2d3289e5 158 SUPERFAMILY SSF56300 1 115 7.9E-17 T 12-10-2018 AFE_0821 13b3efa89ea615242e138a4e2d3289e5 158 Pfam PF00149 Calcineurin-like phosphoesterase 1 91 1.3E-9 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFE_2607 e0078c92b57b9337bb9e539de7c215cc 150 Gene3D G3DSA:1.10.1660.10 22 96 7.2E-19 T 12-10-2018 AFE_2607 e0078c92b57b9337bb9e539de7c215cc 150 SMART SM00422 28 98 2.1E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_2607 e0078c92b57b9337bb9e539de7c215cc 150 SUPERFAMILY SSF46955 28 147 1.14E-15 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFE_2607 e0078c92b57b9337bb9e539de7c215cc 150 Pfam PF13411 MerR HTH family regulatory protein 28 97 3.6E-21 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 22 688 1.6E-269 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 Hamap MF_00347 Polyphosphate kinase [ppk]. 19 696 27.513 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 SUPERFAMILY SSF140356 19 123 5.1E-34 T 12-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 Pfam PF13090 Polyphosphate kinase C-terminal domain 346 679 6.7E-144 T 12-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 Gene3D G3DSA:3.30.1840.10 17 327 9.0E-98 T 12-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 Gene3D G3DSA:3.30.870.10 520 698 1.3E-61 T 12-10-2018 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 Pfam PF13089 Polyphosphate kinase N-terminal domain 22 127 5.7E-34 T 12-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 SUPERFAMILY SSF143724 125 329 2.35E-60 T 12-10-2018 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 SUPERFAMILY SSF56024 517 694 3.36E-64 T 12-10-2018 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 Pfam PF02503 Polyphosphate kinase middle domain 137 336 2.7E-58 T 12-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 PIRSF PIRSF015589 2 701 1.3E-277 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 SUPERFAMILY SSF56024 330 509 4.19E-59 T 12-10-2018 AFE_1876 c9fab2897d5f43227329f50e87137a01 701 Gene3D G3DSA:3.30.870.10 334 516 9.7E-69 T 12-10-2018 AFE_2622 bf65347dc47e09173eaf742f05ce7a9f 163 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 20 141 4.4E-43 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2622 bf65347dc47e09173eaf742f05ce7a9f 163 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 11 147 27.235 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2622 bf65347dc47e09173eaf742f05ce7a9f 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 103 114 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_2622 bf65347dc47e09173eaf742f05ce7a9f 163 SUPERFAMILY SSF54862 37 146 6.28E-25 T 12-10-2018 AFE_2622 bf65347dc47e09173eaf742f05ce7a9f 163 Gene3D G3DSA:3.30.70.3270 37 163 1.8E-36 T 12-10-2018 AFE_2622 bf65347dc47e09173eaf742f05ce7a9f 163 Pfam PF12838 4Fe-4S dicluster domain 63 116 3.4E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_1495 82374b9b32ceefa2723eebb509803345 341 Gene3D G3DSA:1.10.3470.10 8 340 3.0E-93 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFE_1495 82374b9b32ceefa2723eebb509803345 341 Pfam PF01032 FecCD transport family 22 334 1.9E-79 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFE_1495 82374b9b32ceefa2723eebb509803345 341 SUPERFAMILY SSF81345 11 334 5.1E-73 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFE_2557 5ef122357d8bc48fdfaf7dd9df04e177 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 8 32 - T 12-10-2018 IPR001455 TusA-like domain AFE_2557 5ef122357d8bc48fdfaf7dd9df04e177 76 Pfam PF01206 Sulfurtransferase TusA 6 75 4.8E-23 T 12-10-2018 IPR001455 TusA-like domain AFE_2557 5ef122357d8bc48fdfaf7dd9df04e177 76 SUPERFAMILY SSF64307 2 75 8.11E-24 T 12-10-2018 IPR036868 TusA-like domain superfamily AFE_2557 5ef122357d8bc48fdfaf7dd9df04e177 76 Gene3D G3DSA:3.30.110.40 1 76 6.8E-29 T 12-10-2018 IPR036868 TusA-like domain superfamily AFE_1874 577ba77472cf4e84daf7b3a154dfa003 489 SMART SM00880 230 474 8.4E-19 T 12-10-2018 IPR007899 CHAD domain AFE_1874 577ba77472cf4e84daf7b3a154dfa003 489 Pfam PF05235 CHAD domain 232 441 3.5E-29 T 12-10-2018 IPR007899 CHAD domain AFE_1874 577ba77472cf4e84daf7b3a154dfa003 489 Gene3D G3DSA:2.40.320.10 1 197 1.2E-25 T 12-10-2018 AFE_1874 577ba77472cf4e84daf7b3a154dfa003 489 SUPERFAMILY SSF55154 1 207 1.01E-34 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 AFE_1874 577ba77472cf4e84daf7b3a154dfa003 489 SMART SM01118 1 202 5.0E-26 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AFE_1874 577ba77472cf4e84daf7b3a154dfa003 489 Pfam PF01928 CYTH domain 33 195 7.8E-21 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AFE_1874 577ba77472cf4e84daf7b3a154dfa003 489 Gene3D G3DSA:1.40.20.10 211 486 1.2E-31 T 12-10-2018 IPR038186 CHAD domain superfamily AFE_1568 0bbcdb3607182f64025e27e359bb5cbf 296 SUPERFAMILY SSF53335 3 257 1.6E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_1568 0bbcdb3607182f64025e27e359bb5cbf 296 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 9 216 1.2E-26 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 AFE_1568 0bbcdb3607182f64025e27e359bb5cbf 296 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 53 66 2.6E-14 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 AFE_1568 0bbcdb3607182f64025e27e359bb5cbf 296 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 33 47 2.6E-14 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 AFE_1568 0bbcdb3607182f64025e27e359bb5cbf 296 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 9 25 2.6E-14 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 AFE_1568 0bbcdb3607182f64025e27e359bb5cbf 296 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 179 191 2.6E-14 T 12-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 AFE_1568 0bbcdb3607182f64025e27e359bb5cbf 296 PIRSF PIRSF000398 1 278 7.0E-44 T 12-10-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 AFE_1568 0bbcdb3607182f64025e27e359bb5cbf 296 Gene3D G3DSA:3.40.50.150 8 231 9.6E-40 T 12-10-2018 AFE_1568 0bbcdb3607182f64025e27e359bb5cbf 296 Gene3D G3DSA:1.10.1020.10 60 159 9.6E-40 T 12-10-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 1.0E-61 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 1.0E-61 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 176 197 1.0E-61 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 1.0E-61 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 1.0E-61 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 1.0E-61 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 Gene3D G3DSA:3.40.190.80 141 264 1.7E-38 T 12-10-2018 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 18 40 1.0E-26 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 103 122 1.0E-26 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 197 209 1.0E-26 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 155 181 1.0E-26 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 Gene3D G3DSA:3.30.540.10 1 139 9.7E-48 T 12-10-2018 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 SUPERFAMILY SSF56655 3 258 1.7E-84 T 12-10-2018 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 Pfam PF00459 Inositol monophosphatase family 2 254 1.7E-64 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site AFE_0669 bc36c1c95ff1aaa61a88728d2d8dd8c1 267 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 210 224 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 Gene3D G3DSA:3.90.930.12 1 79 5.9E-24 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 SUPERFAMILY SSF56053 80 174 7.07E-37 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 PRINTS PR00059 Ribosomal protein L6 signature 138 159 4.7E-35 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 PRINTS PR00059 Ribosomal protein L6 signature 96 112 4.7E-35 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 PRINTS PR00059 Ribosomal protein L6 signature 68 93 4.7E-35 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 Gene3D G3DSA:3.90.930.12 80 174 2.2E-40 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 PIRSF PIRSF002162 1 174 2.1E-46 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 173 7.7E-73 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 173 37.068 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 SUPERFAMILY SSF56053 1 79 2.49E-20 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 Pfam PF00347 Ribosomal protein L6 87 161 9.3E-22 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 Pfam PF00347 Ribosomal protein L6 12 79 1.4E-13 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0342 346d5dbaf443b7f876d8e02bb82116da 174 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 151 159 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2793 7d1036194d834c0fb21f9210817cf972 525 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 199 1.0E-18 T 12-10-2018 AFE_2793 7d1036194d834c0fb21f9210817cf972 525 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 314 338 1.0E-18 T 12-10-2018 AFE_2793 7d1036194d834c0fb21f9210817cf972 525 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 280 292 1.0E-18 T 12-10-2018 AFE_2793 7d1036194d834c0fb21f9210817cf972 525 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 206 220 1.0E-18 T 12-10-2018 AFE_2793 7d1036194d834c0fb21f9210817cf972 525 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 283 289 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFE_2793 7d1036194d834c0fb21f9210817cf972 525 Gene3D G3DSA:1.20.1260.30 6 149 1.7E-44 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily AFE_2793 7d1036194d834c0fb21f9210817cf972 525 SUPERFAMILY SSF53335 16 524 1.72E-142 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2793 7d1036194d834c0fb21f9210817cf972 525 Gene3D G3DSA:3.40.50.150 160 468 6.6E-120 T 12-10-2018 AFE_2793 7d1036194d834c0fb21f9210817cf972 525 Pfam PF02384 N-6 DNA Methylase 159 484 3.7E-113 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 AFE_2793 7d1036194d834c0fb21f9210817cf972 525 Pfam PF12161 HsdM N-terminal domain 18 147 1.9E-24 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain AFE_1525 97639932d72d02e511afd8520b296656 462 SUPERFAMILY SSF52833 306 417 5.54E-26 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1525 97639932d72d02e511afd8520b296656 462 Gene3D G3DSA:1.10.4080.10 2 295 2.7E-93 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AFE_1525 97639932d72d02e511afd8520b296656 462 Gene3D G3DSA:3.40.30.10 303 416 5.2E-17 T 12-10-2018 AFE_1525 97639932d72d02e511afd8520b296656 462 SUPERFAMILY SSF101478 3 286 6.54E-70 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AFE_1525 97639932d72d02e511afd8520b296656 462 TIGRFAM TIGR01616 nitro_assoc: nitrogenase-associated protein 305 416 3.2E-49 T 12-10-2018 IPR006503 Nitrogenase-associated protein AFE_1525 97639932d72d02e511afd8520b296656 462 TIGRFAM TIGR02662 dinitro_DRAG: ADP-ribosyl-[dinitrogen reductase] hydrolase 5 290 4.2E-152 T 12-10-2018 IPR013479 ADP-ribosyl-dinitrogen reductase hydrolase AFE_1525 97639932d72d02e511afd8520b296656 462 Pfam PF03747 ADP-ribosylglycohydrolase 11 264 1.3E-52 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 AFE_1525 97639932d72d02e511afd8520b296656 462 Pfam PF03960 ArsC family 374 413 2.3E-4 T 12-10-2018 IPR006660 Arsenate reductase-like AFE_0778 a9f87c11e133954c0cfee70bef83204b 194 Pfam PF04115 Ureidoglycolate lyase 72 159 4.3E-11 T 12-10-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 AFE_0778 a9f87c11e133954c0cfee70bef83204b 194 SUPERFAMILY SSF51182 15 153 1.19E-24 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_0778 a9f87c11e133954c0cfee70bef83204b 194 Gene3D G3DSA:2.60.120.480 14 182 6.2E-18 T 12-10-2018 IPR024060 Ureidoglycolate lyase domain superfamily GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 AFE_0557 7b877704fbe9ae4137a3a2c187f23c72 310 Pfam PF01687 Riboflavin kinase 180 302 5.9E-33 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 AFE_0557 7b877704fbe9ae4137a3a2c187f23c72 310 Pfam PF06574 FAD synthetase 15 162 5.0E-44 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFE_0557 7b877704fbe9ae4137a3a2c187f23c72 310 PIRSF PIRSF004491 1 309 6.9E-95 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFE_0557 7b877704fbe9ae4137a3a2c187f23c72 310 Gene3D G3DSA:3.40.50.620 5 181 3.3E-52 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0557 7b877704fbe9ae4137a3a2c187f23c72 310 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 302 2.7E-82 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFE_0557 7b877704fbe9ae4137a3a2c187f23c72 310 SUPERFAMILY SSF82114 170 305 3.27E-41 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFE_0557 7b877704fbe9ae4137a3a2c187f23c72 310 SUPERFAMILY SSF52374 18 171 2.78E-27 T 12-10-2018 AFE_0557 7b877704fbe9ae4137a3a2c187f23c72 310 Gene3D G3DSA:2.40.30.30 182 309 9.3E-35 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFE_0557 7b877704fbe9ae4137a3a2c187f23c72 310 SMART SM00904 179 303 3.4E-49 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 AFE_2729 becb1b4e6626dec81799148a0b5085cc 206 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 15 194 2.7E-60 T 12-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 AFE_2729 becb1b4e6626dec81799148a0b5085cc 206 Pfam PF00355 Rieske [2Fe-2S] domain 121 182 3.1E-8 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFE_2729 becb1b4e6626dec81799148a0b5085cc 206 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 9 45 5.4E-6 T 12-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 AFE_2729 becb1b4e6626dec81799148a0b5085cc 206 Gene3D G3DSA:2.102.10.10 47 196 4.8E-41 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFE_2729 becb1b4e6626dec81799148a0b5085cc 206 SUPERFAMILY SSF50022 37 196 5.08E-32 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFE_2729 becb1b4e6626dec81799148a0b5085cc 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 126 137 5.7E-6 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFE_2729 becb1b4e6626dec81799148a0b5085cc 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 155 167 5.7E-6 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFE_2729 becb1b4e6626dec81799148a0b5085cc 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 168 180 5.7E-6 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFE_2794 1d93cbb4157a809d91893c483ac07782 140 SMART SM00974 4 85 7.5E-11 T 12-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding AFE_2794 1d93cbb4157a809d91893c483ac07782 140 Pfam PF10544 T5orf172 domain 2 79 2.9E-9 T 12-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding AFE_0591 0864b1b0f72702feb7e84cff6b77eacb 720 SUPERFAMILY SSF52540 450 603 5.32E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0591 0864b1b0f72702feb7e84cff6b77eacb 720 Pfam PF00270 DEAD/DEAH box helicase 209 352 4.7E-10 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFE_0591 0864b1b0f72702feb7e84cff6b77eacb 720 TIGRFAM TIGR00595 priA: primosomal protein N' 212 717 7.1E-180 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 AFE_0591 0864b1b0f72702feb7e84cff6b77eacb 720 Gene3D G3DSA:1.10.8.630 6 113 2.0E-29 T 12-10-2018 AFE_0591 0864b1b0f72702feb7e84cff6b77eacb 720 SMART SM00487 187 383 5.2E-12 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_0591 0864b1b0f72702feb7e84cff6b77eacb 720 Pfam PF11331 Probable zinc-ribbon domain 422 460 2.2E-4 T 12-10-2018 IPR021480 Probable zinc-ribbon domain, plant AFE_0591 0864b1b0f72702feb7e84cff6b77eacb 720 SUPERFAMILY SSF52540 188 369 1.8E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0591 0864b1b0f72702feb7e84cff6b77eacb 720 SMART SM00490 484 581 0.0024 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0591 0864b1b0f72702feb7e84cff6b77eacb 720 Gene3D G3DSA:3.40.50.300 181 371 1.1E-69 T 12-10-2018 AFE_0591 0864b1b0f72702feb7e84cff6b77eacb 720 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 719 23.424 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 AFE_0926 e801f57880a754fc8bc9c37ec79308d1 232 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 232 55.831 T 12-10-2018 IPR005224 Sugar fermentation stimulation protein AFE_0926 e801f57880a754fc8bc9c37ec79308d1 232 Pfam PF03749 Sugar fermentation stimulation protein 12 223 1.1E-72 T 12-10-2018 IPR005224 Sugar fermentation stimulation protein AFE_0926 e801f57880a754fc8bc9c37ec79308d1 232 Gene3D G3DSA:2.40.50.580 3 78 2.3E-27 T 12-10-2018 AFE_0926 e801f57880a754fc8bc9c37ec79308d1 232 Gene3D G3DSA:3.40.1350.60 79 231 3.8E-50 T 12-10-2018 AFE_0926 e801f57880a754fc8bc9c37ec79308d1 232 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 1 221 1.3E-64 T 12-10-2018 IPR005224 Sugar fermentation stimulation protein AFE_0808 f3f9963409caa80c072ddcccd8bbd134 349 Gene3D G3DSA:3.30.465.10 1 236 9.5E-73 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFE_0808 f3f9963409caa80c072ddcccd8bbd134 349 Gene3D G3DSA:3.30.390.50 238 343 6.8E-25 T 12-10-2018 AFE_0808 f3f9963409caa80c072ddcccd8bbd134 349 SUPERFAMILY SSF56176 4 234 8.72E-53 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFE_0808 f3f9963409caa80c072ddcccd8bbd134 349 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 4 234 5.4E-39 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 AFE_0808 f3f9963409caa80c072ddcccd8bbd134 349 SUPERFAMILY SSF55447 240 341 6.54E-22 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily AFE_0808 f3f9963409caa80c072ddcccd8bbd134 349 SMART SM01092 241 340 5.5E-23 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFE_0808 f3f9963409caa80c072ddcccd8bbd134 349 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 243 339 8.7E-15 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFE_0622 8b80a47f7a2d75c9759831543b2fae62 270 SMART SM00530 20 92 4.1E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_0622 8b80a47f7a2d75c9759831543b2fae62 270 Gene3D G3DSA:1.10.260.40 27 93 4.0E-7 T 12-10-2018 AFE_0622 8b80a47f7a2d75c9759831543b2fae62 270 Gene3D G3DSA:3.30.450.180 114 270 2.7E-14 T 12-10-2018 AFE_0622 8b80a47f7a2d75c9759831543b2fae62 270 Pfam PF13560 Helix-turn-helix domain 17 95 8.7E-15 T 12-10-2018 AFE_0622 8b80a47f7a2d75c9759831543b2fae62 270 SUPERFAMILY SSF47413 40 91 3.15E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_0152 84bd68b68616d08cc79512ba6bc69292 127 Pfam PF04241 Protein of unknown function (DUF423) 23 110 2.0E-31 T 12-10-2018 IPR006696 Protein of unknown function DUF423 AFE_2117 530210619aff4838e3abc854bd48a839 338 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 9 308 1.2E-27 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFE_2117 530210619aff4838e3abc854bd48a839 338 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 21 301 1.7E-12 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFE_2117 530210619aff4838e3abc854bd48a839 338 TIGRFAM TIGR03476 HpnL: putative membrane protein 4 319 1.3E-121 T 12-10-2018 AFE_2011 3c6282f0926c7d242d1af6736a70438c 203 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFE_2011 3c6282f0926c7d242d1af6736a70438c 203 SUPERFAMILY SSF46689 6 87 1.4E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_2011 3c6282f0926c7d242d1af6736a70438c 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 4.2E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFE_2011 3c6282f0926c7d242d1af6736a70438c 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 4.2E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFE_2011 3c6282f0926c7d242d1af6736a70438c 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 65 4.2E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFE_2011 3c6282f0926c7d242d1af6736a70438c 203 Gene3D G3DSA:1.10.357.10 16 196 3.2E-31 T 12-10-2018 AFE_3023 16b4f50874fc3c6f33df59f62f803305 148 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 50 66 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain AFE_3023 16b4f50874fc3c6f33df59f62f803305 148 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 146 1.4E-30 T 12-10-2018 IPR002178 PTS EIIA type-2 domain AFE_3023 16b4f50874fc3c6f33df59f62f803305 148 Gene3D G3DSA:3.40.930.10 3 147 3.5E-39 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 AFE_3023 16b4f50874fc3c6f33df59f62f803305 148 SUPERFAMILY SSF55804 7 146 4.45E-33 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 Pfam PF00549 CoA-ligase 262 382 1.3E-24 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 4.1E-152 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 Gene3D G3DSA:3.40.50.261 240 387 7.3E-56 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 SUPERFAMILY SSF52210 240 385 5.76E-52 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 Gene3D G3DSA:3.30.470.20 1 232 4.0E-86 T 12-10-2018 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 Pfam PF08442 ATP-grasp domain 2 202 4.1E-72 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 42.89 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 Gene3D G3DSA:3.30.1490.20 21 104 4.0E-86 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 SUPERFAMILY SSF56059 1 237 2.95E-71 T 12-10-2018 AFE_0425 67c9bf0fc0e63dc50eb52f955ac0ca99 387 PIRSF PIRSF001554 1 387 1.8E-145 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFE_1304 9e16d8fa7ab64fd0136d5dabcd137c15 209 Gene3D G3DSA:3.40.50.1390 56 158 1.1E-21 T 12-10-2018 AFE_1304 9e16d8fa7ab64fd0136d5dabcd137c15 209 ProSitePatterns PS00397 Site-specific recombinases active site. 63 71 - T 12-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AFE_1304 9e16d8fa7ab64fd0136d5dabcd137c15 209 SUPERFAMILY SSF53041 59 189 7.59E-21 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFE_1304 9e16d8fa7ab64fd0136d5dabcd137c15 209 SMART SM00857 60 194 3.7E-19 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFE_1304 9e16d8fa7ab64fd0136d5dabcd137c15 209 SUPERFAMILY SSF46955 5 50 8.7E-11 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFE_1304 9e16d8fa7ab64fd0136d5dabcd137c15 209 Gene3D G3DSA:1.10.1660.10 6 52 1.1E-12 T 12-10-2018 AFE_1304 9e16d8fa7ab64fd0136d5dabcd137c15 209 Pfam PF00239 Resolvase, N terminal domain 61 187 2.4E-18 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFE_1304 9e16d8fa7ab64fd0136d5dabcd137c15 209 SMART SM00422 5 78 0.0032 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_1304 9e16d8fa7ab64fd0136d5dabcd137c15 209 Pfam PF13411 MerR HTH family regulatory protein 5 50 2.1E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_2564 6997880e58f19de118d9be09b4a31b94 158 Pfam PF04093 rod shape-determining protein MreD 5 147 1.9E-11 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 AFE_2564 6997880e58f19de118d9be09b4a31b94 158 PIRSF PIRSF018472 1 156 3.0E-29 T 12-10-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type AFE_2564 6997880e58f19de118d9be09b4a31b94 158 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 3 146 1.2E-24 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 SUPERFAMILY SSF63418 1 98 9.42E-21 T 12-10-2018 IPR035911 MurE/MurF, N-terminal AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 Gene3D G3DSA:3.90.190.20 312 449 4.4E-39 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 SUPERFAMILY SSF53623 101 310 6.93E-52 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 445 1.8E-123 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 Gene3D G3DSA:3.40.1390.10 1 81 1.7E-18 T 12-10-2018 AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 392 8.1E-11 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 Pfam PF01225 Mur ligase family, catalytic domain 26 74 4.5E-8 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 SUPERFAMILY SSF53244 314 445 1.12E-33 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 446 32.44 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 Gene3D G3DSA:3.40.1190.10 82 311 5.1E-70 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFE_0210 0c2f4154bdc783d16dbeb9047af2a8a7 450 Pfam PF08245 Mur ligase middle domain 106 293 1.1E-43 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFE_0552 7359f4c8d6bbb6400c3d5c00976113b4 587 Gene3D G3DSA:1.20.1560.10 2 348 2.1E-6 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_0552 7359f4c8d6bbb6400c3d5c00976113b4 587 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_0552 7359f4c8d6bbb6400c3d5c00976113b4 587 Pfam PF00005 ABC transporter 387 520 4.2E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0552 7359f4c8d6bbb6400c3d5c00976113b4 587 SUPERFAMILY SSF52540 352 568 4.61E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0552 7359f4c8d6bbb6400c3d5c00976113b4 587 Pfam PF06472 ABC transporter transmembrane region 2 3 298 3.4E-64 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFE_0552 7359f4c8d6bbb6400c3d5c00976113b4 587 Gene3D G3DSA:3.40.50.300 363 574 5.9E-38 T 12-10-2018 AFE_0552 7359f4c8d6bbb6400c3d5c00976113b4 587 SMART SM00382 395 568 5.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0552 7359f4c8d6bbb6400c3d5c00976113b4 587 SUPERFAMILY SSF90123 11 342 1.22E-21 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_0978 b49f044e5ed77a2edbcbc730625db13f 109 Gene3D G3DSA:3.30.450.30 6 106 3.6E-14 T 12-10-2018 AFE_0978 b49f044e5ed77a2edbcbc730625db13f 109 SUPERFAMILY SSF103196 13 92 1.31E-11 T 12-10-2018 AFE_0978 b49f044e5ed77a2edbcbc730625db13f 109 Pfam PF03259 Roadblock/LC7 domain 9 88 5.7E-13 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFE_0978 b49f044e5ed77a2edbcbc730625db13f 109 SMART SM00960 3 90 0.0027 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFE_0002 119ec50263cc2247da4685731942a201 350 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 316 4.0E-12 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AFE_0002 119ec50263cc2247da4685731942a201 350 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 350 58.977 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 AFE_0002 119ec50263cc2247da4685731942a201 350 Gene3D G3DSA:1.20.1050.90 114 289 1.1E-57 T 12-10-2018 AFE_0002 119ec50263cc2247da4685731942a201 350 Gene3D G3DSA:3.40.50.300 6 322 1.1E-57 T 12-10-2018 AFE_0002 119ec50263cc2247da4685731942a201 350 SUPERFAMILY SSF52540 1 321 6.13E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0002 119ec50263cc2247da4685731942a201 350 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 332 2.9E-62 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 AFE_3030 c7af11c7449c0622a591954937db0234 328 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 49 318 2.3E-104 T 12-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 AFE_3030 c7af11c7449c0622a591954937db0234 328 SUPERFAMILY SSF53697 15 263 8.45E-63 T 12-10-2018 AFE_3030 c7af11c7449c0622a591954937db0234 328 SMART SM00116 214 262 0.75 T 12-10-2018 IPR000644 CBS domain AFE_3030 c7af11c7449c0622a591954937db0234 328 SMART SM00116 279 327 0.0034 T 12-10-2018 IPR000644 CBS domain AFE_3030 c7af11c7449c0622a591954937db0234 328 Pfam PF00571 CBS domain 205 261 7.5E-6 T 12-10-2018 IPR000644 CBS domain AFE_3030 c7af11c7449c0622a591954937db0234 328 Pfam PF00571 CBS domain 279 325 8.1E-6 T 12-10-2018 IPR000644 CBS domain AFE_3030 c7af11c7449c0622a591954937db0234 328 PIRSF PIRSF004692 2 328 1.8E-129 T 12-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 AFE_3030 c7af11c7449c0622a591954937db0234 328 Gene3D G3DSA:3.40.50.10490 8 199 6.6E-60 T 12-10-2018 AFE_3030 c7af11c7449c0622a591954937db0234 328 SUPERFAMILY SSF54631 270 325 5.65E-7 T 12-10-2018 AFE_3030 c7af11c7449c0622a591954937db0234 328 Pfam PF01380 SIS domain 44 175 3.8E-27 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFE_3030 c7af11c7449c0622a591954937db0234 328 Gene3D G3DSA:3.10.580.10 200 325 1.2E-42 T 12-10-2018 AFE_1241 28fbbc32f5a81d5901309f2036cf8ae8 91 SUPERFAMILY SSF47729 7 88 3.09E-20 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_1241 28fbbc32f5a81d5901309f2036cf8ae8 91 Gene3D G3DSA:4.10.520.10 3 91 2.3E-23 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_1241 28fbbc32f5a81d5901309f2036cf8ae8 91 SMART SM00411 5 91 1.1E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1241 28fbbc32f5a81d5901309f2036cf8ae8 91 Pfam PF00216 Bacterial DNA-binding protein 7 89 9.9E-22 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1241 28fbbc32f5a81d5901309f2036cf8ae8 91 PRINTS PR01727 Prokaryotic integration host factor signature 63 76 1.5E-8 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1241 28fbbc32f5a81d5901309f2036cf8ae8 91 PRINTS PR01727 Prokaryotic integration host factor signature 45 60 1.5E-8 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1241 28fbbc32f5a81d5901309f2036cf8ae8 91 PRINTS PR01727 Prokaryotic integration host factor signature 79 91 1.5E-8 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_2012 eca11b2d84eec4eb6ff76f17edd05a50 118 Pfam PF17074 Darcynin, domain of unknown function 6 112 3.9E-33 T 12-10-2018 IPR031409 Darcynin AFE_2012 eca11b2d84eec4eb6ff76f17edd05a50 118 ProDom PD888784 DARCYNIN HOMOLOG 44 102 3.0E-12 T 12-10-2018 AFE_0776 042d25761767c7e6985db15f1a7de934 149 Pfam PF01799 [2Fe-2S] binding domain 72 141 3.4E-24 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFE_0776 042d25761767c7e6985db15f1a7de934 149 SUPERFAMILY SSF54292 2 77 1.19E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFE_0776 042d25761767c7e6985db15f1a7de934 149 SUPERFAMILY SSF47741 72 146 4.84E-27 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily AFE_0776 042d25761767c7e6985db15f1a7de934 149 Gene3D G3DSA:1.10.150.120 76 147 2.0E-24 T 12-10-2018 AFE_0776 042d25761767c7e6985db15f1a7de934 149 Gene3D G3DSA:3.10.20.30 1 75 3.9E-28 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_0776 042d25761767c7e6985db15f1a7de934 149 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFE_0776 042d25761767c7e6985db15f1a7de934 149 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 55 1.3E-5 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFE_2350 370ce1284a31b8e8ce0f00cf122c0b99 323 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 168 181 3.6E-14 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFE_2350 370ce1284a31b8e8ce0f00cf122c0b99 323 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 88 99 3.6E-14 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFE_2350 370ce1284a31b8e8ce0f00cf122c0b99 323 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 141 158 3.6E-14 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFE_2350 370ce1284a31b8e8ce0f00cf122c0b99 323 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 58 280 5.3E-58 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 AFE_2350 370ce1284a31b8e8ce0f00cf122c0b99 323 Gene3D G3DSA:3.40.710.10 48 306 2.8E-73 T 12-10-2018 AFE_2350 370ce1284a31b8e8ce0f00cf122c0b99 323 SUPERFAMILY SSF56601 32 305 4.26E-66 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_2976 47fd531bad685087422e1776b713a4a2 389 SUPERFAMILY SSF53756 63 384 9.42E-44 T 12-10-2018 AFE_2976 47fd531bad685087422e1776b713a4a2 389 Gene3D G3DSA:3.40.50.2000 115 378 4.2E-32 T 12-10-2018 AFE_2976 47fd531bad685087422e1776b713a4a2 389 Pfam PF00534 Glycosyl transferases group 1 211 332 1.4E-21 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_2976 47fd531bad685087422e1776b713a4a2 389 Gene3D G3DSA:3.40.50.2000 195 367 4.2E-32 T 12-10-2018 AFE_3212 4f149482327470912576e5536675b552 260 PIRSF PIRSF009320 101 258 4.9E-9 T 12-10-2018 AFE_3212 4f149482327470912576e5536675b552 260 PIRSF PIRSF009320 8 59 1.9E-16 T 12-10-2018 AFE_3212 4f149482327470912576e5536675b552 260 SUPERFAMILY SSF52540 8 256 6.99E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3212 4f149482327470912576e5536675b552 260 Pfam PF13614 AAA domain 8 182 1.0E-57 T 12-10-2018 IPR025669 AAA domain AFE_3212 4f149482327470912576e5536675b552 260 PRINTS PR00091 Nitrogenase component II signature 15 28 6.8E-5 T 12-10-2018 AFE_3212 4f149482327470912576e5536675b552 260 PRINTS PR00091 Nitrogenase component II signature 37 52 6.8E-5 T 12-10-2018 AFE_3212 4f149482327470912576e5536675b552 260 Gene3D G3DSA:3.40.50.300 5 258 2.1E-75 T 12-10-2018 AFE_1723 b6e01a34d56953b6f75ad46dabd18c0c 332 Pfam PF00248 Aldo/keto reductase family 15 309 3.2E-66 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFE_1723 b6e01a34d56953b6f75ad46dabd18c0c 332 PRINTS PR00069 Aldo-keto reductase signature 140 157 2.2E-10 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFE_1723 b6e01a34d56953b6f75ad46dabd18c0c 332 PRINTS PR00069 Aldo-keto reductase signature 109 127 2.2E-10 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFE_1723 b6e01a34d56953b6f75ad46dabd18c0c 332 PRINTS PR00069 Aldo-keto reductase signature 43 67 2.2E-10 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFE_1723 b6e01a34d56953b6f75ad46dabd18c0c 332 SUPERFAMILY SSF51430 1 321 9.95E-95 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFE_1723 b6e01a34d56953b6f75ad46dabd18c0c 332 Gene3D G3DSA:3.20.20.100 1 328 1.2E-116 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFE_1275 5bd1ed494977f14d770283904f076854 303 Pfam PF11348 Protein of unknown function (DUF3150) 5 241 1.2E-36 T 12-10-2018 IPR021496 Protein of unknown function DUF3150 AFE_0230 901d30c8829c09ae4f017b4374291686 336 Pfam PF13692 Glycosyl transferases group 1 167 303 5.4E-18 T 12-10-2018 AFE_0230 901d30c8829c09ae4f017b4374291686 336 Gene3D G3DSA:3.40.50.2000 5 140 5.5E-42 T 12-10-2018 AFE_0230 901d30c8829c09ae4f017b4374291686 336 Gene3D G3DSA:3.40.50.2000 141 319 5.5E-42 T 12-10-2018 AFE_0230 901d30c8829c09ae4f017b4374291686 336 Pfam PF13439 Glycosyltransferase Family 4 3 141 4.2E-12 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_0230 901d30c8829c09ae4f017b4374291686 336 SUPERFAMILY SSF53756 2 332 1.39E-53 T 12-10-2018 AFE_1130 57aed6a6716b64a75fbb7b06d0395fda 41 Gene3D G3DSA:1.10.10.10 1 40 6.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1130 57aed6a6716b64a75fbb7b06d0395fda 41 SMART SM00843 2 41 3.3E-7 T 12-10-2018 IPR018541 FtsK gamma domain AFE_1130 57aed6a6716b64a75fbb7b06d0395fda 41 Pfam PF09397 Ftsk gamma domain 1 38 3.9E-16 T 12-10-2018 IPR018541 FtsK gamma domain AFE_1130 57aed6a6716b64a75fbb7b06d0395fda 41 SUPERFAMILY SSF46785 1 39 2.02E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1266 96fa308e3f908186888cd9d9ee43bd3c 705 Gene3D G3DSA:3.40.50.300 247 435 1.4E-5 T 12-10-2018 AFE_1266 96fa308e3f908186888cd9d9ee43bd3c 705 Pfam PF05729 NACHT domain 281 460 1.4E-9 T 12-10-2018 IPR007111 NACHT nucleoside triphosphatase AFE_1266 96fa308e3f908186888cd9d9ee43bd3c 705 SUPERFAMILY SSF52540 263 459 6.71E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1847 24f550b28c7c19a51b015f2b476a4922 362 Pfam PF03595 Voltage-dependent anion channel 18 342 4.3E-47 T 12-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 AFE_0941 3bb2f3f0591c3f2543f64787c4094761 639 Gene3D G3DSA:1.10.530.10 468 632 3.0E-37 T 12-10-2018 AFE_0941 3bb2f3f0591c3f2543f64787c4094761 639 SUPERFAMILY SSF53955 472 628 3.6E-35 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFE_0941 3bb2f3f0591c3f2543f64787c4094761 639 SUPERFAMILY SSF48435 22 461 4.71E-54 T 12-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 AFE_0941 3bb2f3f0591c3f2543f64787c4094761 639 Gene3D G3DSA:1.25.20.10 20 379 2.1E-38 T 12-10-2018 AFE_0941 3bb2f3f0591c3f2543f64787c4094761 639 Pfam PF01464 Transglycosylase SLT domain 477 581 8.3E-20 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 AFE_0032 3728a49451ad3d36464fa487e060222e 528 Pfam PF14849 YidC periplasmic domain 72 330 7.4E-65 T 12-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain AFE_0032 3728a49451ad3d36464fa487e060222e 528 PRINTS PR01900 YidC translocation/secretion protein signature 328 344 1.0E-23 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 PRINTS PR01900 YidC translocation/secretion protein signature 476 500 1.0E-23 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 PRINTS PR01900 YidC translocation/secretion protein signature 457 472 1.0E-23 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 Pfam PF02096 60Kd inner membrane protein 343 521 3.5E-56 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 342 521 1.6E-66 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0032 3728a49451ad3d36464fa487e060222e 528 Gene3D G3DSA:2.70.98.90 67 322 7.2E-59 T 12-10-2018 IPR038221 YidC, periplasmic domain superfamily AFE_0032 3728a49451ad3d36464fa487e060222e 528 PRINTS PR00701 60kDa inner membrane protein signature 313 333 5.5E-59 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 PRINTS PR00701 60kDa inner membrane protein signature 487 510 5.5E-59 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 PRINTS PR00701 60kDa inner membrane protein signature 2 23 5.5E-59 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 PRINTS PR00701 60kDa inner membrane protein signature 77 98 5.5E-59 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 PRINTS PR00701 60kDa inner membrane protein signature 451 473 5.5E-59 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 PRINTS PR00701 60kDa inner membrane protein signature 241 256 5.5E-59 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 PRINTS PR00701 60kDa inner membrane protein signature 404 427 5.5E-59 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 523 21.929 T 12-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 AFE_0032 3728a49451ad3d36464fa487e060222e 528 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 341 3.7E-92 T 12-10-2018 IPR028053 Membrane insertase YidC, N-terminal AFE_0334 61157d11410a807525bdb8723861f28a 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 39.592 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0334 61157d11410a807525bdb8723861f28a 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0334 61157d11410a807525bdb8723861f28a 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0334 61157d11410a807525bdb8723861f28a 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 4.5E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0334 61157d11410a807525bdb8723861f28a 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 4.5E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0334 61157d11410a807525bdb8723861f28a 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 4.5E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0334 61157d11410a807525bdb8723861f28a 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 4.5E-41 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0334 61157d11410a807525bdb8723861f28a 138 Gene3D G3DSA:3.90.1170.10 1 137 1.3E-56 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 AFE_0334 61157d11410a807525bdb8723861f28a 138 SUPERFAMILY SSF54686 1 135 1.57E-55 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 AFE_0334 61157d11410a807525bdb8723861f28a 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 4.4E-60 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0334 61157d11410a807525bdb8723861f28a 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.5E-49 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AFE_1349 2854f3ce8678de9d3808ced2427cca8e 387 Gene3D G3DSA:3.40.50.2000 23 173 1.6E-55 T 12-10-2018 AFE_1349 2854f3ce8678de9d3808ced2427cca8e 387 Pfam PF00534 Glycosyl transferases group 1 189 359 2.3E-33 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1349 2854f3ce8678de9d3808ced2427cca8e 387 SUPERFAMILY SSF53756 15 374 5.71E-66 T 12-10-2018 AFE_1349 2854f3ce8678de9d3808ced2427cca8e 387 Gene3D G3DSA:3.40.50.2000 174 363 1.6E-55 T 12-10-2018 AFE_0936 8595c1118048ebaac6f4371a0f690e40 172 Pfam PF01750 Hydrogenase maturation protease 49 140 2.7E-6 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_0936 8595c1118048ebaac6f4371a0f690e40 172 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 6 148 1.6E-26 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_0936 8595c1118048ebaac6f4371a0f690e40 172 Gene3D G3DSA:3.40.50.1450 4 157 7.9E-28 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFE_0936 8595c1118048ebaac6f4371a0f690e40 172 SUPERFAMILY SSF53163 3 159 4.18E-21 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFE_3269 7123a9005a924cdd4c25d8d03c284f95 140 Pfam PF13470 PIN domain 2 116 8.7E-17 T 12-10-2018 IPR002716 PIN domain AFE_3269 7123a9005a924cdd4c25d8d03c284f95 140 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 121 6.9E-17 T 12-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component AFE_3269 7123a9005a924cdd4c25d8d03c284f95 140 SUPERFAMILY SSF88723 2 127 2.47E-9 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 Gene3D G3DSA:3.30.1490.70 184 270 5.3E-11 T 12-10-2018 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 PIRSF PIRSF001604 173 608 2.6E-93 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 PIRSF PIRSF001604 1 192 3.4E-19 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 Hamap MF_01588 DNA ligase [ligA]. 1 607 28.79 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 271 341 2.3E-20 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 SUPERFAMILY SSF52113 533 601 2.04E-12 T 12-10-2018 IPR036420 BRCT domain superfamily AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 204 266 2.1E-8 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 8 134 2.1E-15 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 Gene3D G3DSA:2.40.50.140 271 340 1.5E-22 T 12-10-2018 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 SUPERFAMILY SSF56091 3 264 3.45E-39 T 12-10-2018 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 SUPERFAMILY SSF50249 268 343 1.88E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 SMART SM00532 3 389 1.2E-38 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 Gene3D G3DSA:3.30.470.90 58 181 5.4E-11 T 12-10-2018 AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 SUPERFAMILY SSF47781 348 502 2.54E-17 T 12-10-2018 IPR010994 RuvA domain 2-like AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 Gene3D G3DSA:3.40.50.10190 533 608 4.7E-20 T 12-10-2018 IPR036420 BRCT domain superfamily AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 SMART SM00292 533 609 0.0064 T 12-10-2018 IPR001357 BRCT domain AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 534 601 1.2E-6 T 12-10-2018 IPR001357 BRCT domain AFE_1230 a249a0c0cd7aba446bb7986ff484d680 609 Gene3D G3DSA:1.10.150.20 447 520 3.0E-5 T 12-10-2018 AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 131 1.8E-9 T 12-10-2018 AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 SUPERFAMILY SSF55874 7 211 3.14E-48 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 99 105 - T 12-10-2018 IPR014762 DNA mismatch repair, conserved site AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 Pfam PF08676 MutL C terminal dimerisation domain 411 551 1.6E-33 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 Gene3D G3DSA:3.30.1370.100 455 548 4.5E-50 T 12-10-2018 AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 218 334 2.3E-37 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 7 591 26.813 T 12-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 Gene3D G3DSA:3.30.230.10 222 334 2.3E-35 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 8 315 9.0E-93 T 12-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 SMART SM00853 415 551 4.0E-36 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 SUPERFAMILY SSF118116 410 593 9.55E-48 T 12-10-2018 IPR037198 MutL, C-terminal domain superfamily AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 Gene3D G3DSA:3.30.565.10 8 221 3.3E-62 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 Gene3D G3DSA:2.30.42.20 416 593 4.5E-50 T 12-10-2018 AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 SUPERFAMILY SSF54211 202 335 3.79E-36 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_1927 8eda9d84765240f424bff67b544ce9c5 595 SMART SM01340 217 335 6.7E-57 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 AFE_0630 b496c5d2f0d988bf87b2a9f4ff2355b5 250 Pfam PF17124 ThiJ/PfpI family-like 27 154 6.8E-14 T 12-10-2018 IPR032633 ThiJ/PfpI family-like AFE_0630 b496c5d2f0d988bf87b2a9f4ff2355b5 250 SUPERFAMILY SSF52317 6 237 1.87E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_0630 b496c5d2f0d988bf87b2a9f4ff2355b5 250 Gene3D G3DSA:3.40.50.880 1 240 3.5E-60 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 554 570 6.6E-42 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 426 444 6.6E-42 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 526 542 6.6E-42 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 716 737 6.6E-42 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 585 610 6.6E-42 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 SUPERFAMILY SSF81653 119 215 3.01E-29 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 Pfam PF00122 E1-E2 ATPase 119 294 6.3E-52 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 Gene3D G3DSA:2.60.120.1500 116 205 7.7E-33 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 SMART SM00831 6 80 2.0E-22 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 TIGRFAM TIGR01647 ATPase-IIIA_H: plasma-membrane proton-efflux P-type ATPase 27 763 1.1E-300 T 12-10-2018 IPR006534 P-type ATPase, subfamily IIIA GO:0008553|GO:0016021|GO:0120029 KEGG: 00190+3.6.3.6 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 SUPERFAMILY SSF81665 12 799 1.1E-85 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 Pfam PF00690 Cation transporter/ATPase, N-terminus 14 75 5.4E-16 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 501 3.2E-59 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 516 645 1.6E-30 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 Gene3D G3DSA:1.20.1110.10 523 797 1.5E-60 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 Gene3D G3DSA:1.20.1110.10 206 334 1.3E-30 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 SUPERFAMILY SSF56784 311 604 5.82E-39 T 12-10-2018 IPR036412 HAD-like superfamily AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 573 2.0E-40 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 577 589 2.0E-40 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 179 2.0E-40 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 478 488 2.0E-40 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 456 467 2.0E-40 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 315 329 2.0E-40 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 Gene3D G3DSA:3.40.1110.10 335 457 2.0E-28 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 Pfam PF00702 haloacid dehalogenase-like hydrolase 311 568 4.2E-20 T 12-10-2018 AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 Gene3D G3DSA:3.40.50.1000 458 522 3.8E-5 T 12-10-2018 IPR023214 HAD superfamily AFE_0818 1fbcc4b0874669aed9e14831ac742c97 809 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 317 323 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFE_0122 950232d46d184c5bf58d654e5ced9cdf 117 Pfam PF04305 Protein of unknown function (DUF455) 27 108 1.6E-18 T 12-10-2018 IPR007402 Protein of unknown function DUF455 AFE_0006 4a47c40409519ba74d39fec2cd6e1f37 247 SUPERFAMILY SSF49354 28 148 5.63E-20 T 12-10-2018 IPR008962 PapD-like superfamily AFE_0006 4a47c40409519ba74d39fec2cd6e1f37 247 Gene3D G3DSA:2.60.40.10 30 149 3.5E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold AFE_0006 4a47c40409519ba74d39fec2cd6e1f37 247 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 37 148 3.3E-18 T 12-10-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 AFE_0734 780166b74d5872f4c7ee4e8e5592c38d 179 PRINTS PR01100 Shikimate kinase family signature 76 85 2.9E-23 T 12-10-2018 AFE_0734 780166b74d5872f4c7ee4e8e5592c38d 179 PRINTS PR01100 Shikimate kinase family signature 29 42 2.9E-23 T 12-10-2018 AFE_0734 780166b74d5872f4c7ee4e8e5592c38d 179 PRINTS PR01100 Shikimate kinase family signature 97 114 2.9E-23 T 12-10-2018 AFE_0734 780166b74d5872f4c7ee4e8e5592c38d 179 PRINTS PR01100 Shikimate kinase family signature 57 65 2.9E-23 T 12-10-2018 AFE_0734 780166b74d5872f4c7ee4e8e5592c38d 179 PRINTS PR01100 Shikimate kinase family signature 5 20 2.9E-23 T 12-10-2018 AFE_0734 780166b74d5872f4c7ee4e8e5592c38d 179 Pfam PF01202 Shikimate kinase 11 168 4.2E-46 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFE_0734 780166b74d5872f4c7ee4e8e5592c38d 179 ProSitePatterns PS01128 Shikimate kinase signature. 58 84 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFE_0734 780166b74d5872f4c7ee4e8e5592c38d 179 Gene3D G3DSA:3.40.50.300 2 175 9.6E-52 T 12-10-2018 AFE_0734 780166b74d5872f4c7ee4e8e5592c38d 179 SUPERFAMILY SSF52540 5 168 1.46E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0734 780166b74d5872f4c7ee4e8e5592c38d 179 Hamap MF_00109 Shikimate kinase [aroK]. 2 169 27.547 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 Gene3D G3DSA:3.40.50.10490 11 496 1.1E-221 T 12-10-2018 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 Gene3D G3DSA:3.40.50.10490 96 289 1.1E-221 T 12-10-2018 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 455 473 9.0E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 336 357 9.0E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 473 487 9.0E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 487 500 9.0E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 148 167 9.0E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 259 277 9.0E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 Pfam PF00342 Phosphoglucose isomerase 50 530 3.2E-201 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 263 276 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 Gene3D G3DSA:1.10.1390.10 497 537 1.5E-16 T 12-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 487 504 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 44 514 39.734 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_2924 630734c30ee6ccec38f58ea120b0a233 539 SUPERFAMILY SSF53697 5 537 5.28E-199 T 12-10-2018 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 21 320 7.7E-88 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 20 323 39.724 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 67 74 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 274 283 1.0E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 286 309 1.0E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 67 86 1.0E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 153 164 1.0E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 Gene3D G3DSA:3.40.50.1370 21 319 6.9E-86 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 21 165 2.0E-40 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 Gene3D G3DSA:3.40.50.1370 153 308 6.9E-86 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 PRINTS PR00101 Aspartate carbamoyltransferase signature 302 316 1.5E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 PRINTS PR00101 Aspartate carbamoyltransferase signature 95 104 1.5E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 PRINTS PR00101 Aspartate carbamoyltransferase signature 57 79 1.5E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 PRINTS PR00101 Aspartate carbamoyltransferase signature 237 246 1.5E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 PRINTS PR00101 Aspartate carbamoyltransferase signature 152 169 1.5E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 PRINTS PR00101 Aspartate carbamoyltransferase signature 278 283 1.5E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 175 319 3.1E-21 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AFE_3059 baae4c0a1c18352c3cdd42e3dde3872c 327 SUPERFAMILY SSF53671 19 322 2.75E-87 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFE_1584 2ba12cda913b802ac9dbe36138b547d4 91 SMART SM00411 1 90 8.0E-26 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1584 2ba12cda913b802ac9dbe36138b547d4 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.4E-27 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1584 2ba12cda913b802ac9dbe36138b547d4 91 Gene3D G3DSA:4.10.520.10 1 91 2.2E-28 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_1584 2ba12cda913b802ac9dbe36138b547d4 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AFE_1584 2ba12cda913b802ac9dbe36138b547d4 91 SUPERFAMILY SSF47729 1 90 1.77E-24 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_1584 2ba12cda913b802ac9dbe36138b547d4 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.8E-10 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1584 2ba12cda913b802ac9dbe36138b547d4 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.8E-10 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1584 2ba12cda913b802ac9dbe36138b547d4 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.8E-10 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_2825 427713c6d48440ae52a0eac4a22ec330 354 SUPERFAMILY SSF51445 13 300 2.63E-82 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFE_2825 427713c6d48440ae52a0eac4a22ec330 354 Gene3D G3DSA:3.20.20.300 11 350 2.2E-109 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 AFE_2825 427713c6d48440ae52a0eac4a22ec330 354 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 17 304 1.6E-72 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 AFE_2825 427713c6d48440ae52a0eac4a22ec330 354 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 14 351 46.736 T 12-10-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 AFE_2825 427713c6d48440ae52a0eac4a22ec330 354 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 248 265 - T 12-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 AFE_2985 418e94a055263ba964b639016c47264b 618 SMART SM00382 397 588 8.0E-23 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2985 418e94a055263ba964b639016c47264b 618 Pfam PF00005 ABC transporter 389 542 6.7E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2985 418e94a055263ba964b639016c47264b 618 SUPERFAMILY SSF52540 360 612 1.64E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2985 418e94a055263ba964b639016c47264b 618 Gene3D G3DSA:1.20.1560.10 31 348 4.3E-33 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_2985 418e94a055263ba964b639016c47264b 618 Pfam PF00664 ABC transporter transmembrane region 44 310 4.4E-22 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFE_2985 418e94a055263ba964b639016c47264b 618 SUPERFAMILY SSF90123 33 347 1.7E-49 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_2985 418e94a055263ba964b639016c47264b 618 ProSitePatterns PS00211 ABC transporters family signature. 514 528 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2985 418e94a055263ba964b639016c47264b 618 Gene3D G3DSA:3.40.50.300 357 618 6.2E-87 T 12-10-2018 AFE_2302 91630e03bf7e39a41c7b6bda37fc6712 738 Pfam PF00593 TonB dependent receptor 251 735 1.1E-44 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_2302 91630e03bf7e39a41c7b6bda37fc6712 738 Gene3D G3DSA:2.40.170.20 164 738 4.7E-68 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily AFE_2302 91630e03bf7e39a41c7b6bda37fc6712 738 SUPERFAMILY SSF56935 24 738 9.16E-89 T 12-10-2018 AFE_2302 91630e03bf7e39a41c7b6bda37fc6712 738 Gene3D G3DSA:2.170.130.10 29 159 1.8E-11 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_2302 91630e03bf7e39a41c7b6bda37fc6712 738 Pfam PF07715 TonB-dependent Receptor Plug Domain 44 144 3.6E-11 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain AFE_1896 1fbe528371df4a39695e7c67a410bdfb 219 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 4 190 30.201 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 AFE_1896 1fbe528371df4a39695e7c67a410bdfb 219 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 192 6.1E-67 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 AFE_1896 1fbe528371df4a39695e7c67a410bdfb 219 SUPERFAMILY SSF53328 3 198 6.93E-60 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFE_1896 1fbe528371df4a39695e7c67a410bdfb 219 Pfam PF00551 Formyl transferase 3 184 7.1E-55 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFE_1896 1fbe528371df4a39695e7c67a410bdfb 219 Gene3D G3DSA:3.40.50.170 2 208 6.0E-73 T 12-10-2018 AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 285 298 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 Pfam PF02881 SRP54-type protein, helical bundle domain 36 93 5.5E-10 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 40 312 57.673 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 SMART SM00963 16 97 2.2E-22 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 42 311 4.2E-102 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 Pfam PF00448 SRP54-type protein, GTPase domain 112 311 1.2E-73 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 Gene3D G3DSA:3.40.50.300 111 300 1.8E-110 T 12-10-2018 AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 SMART SM00962 111 312 1.5E-108 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 SMART SM00382 110 290 4.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 SUPERFAMILY SSF52540 62 311 1.14E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2753 8fcd7d2e8d32c2cdc73bc3aa6b688251 316 Gene3D G3DSA:1.20.120.140 13 310 1.8E-110 T 12-10-2018 AFE_2120 9330b2333e85e061abda6758b39983ad 476 Pfam PF04055 Radical SAM superfamily 205 364 3.4E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_2120 9330b2333e85e061abda6758b39983ad 476 SMART SM00729 199 407 2.2E-31 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFE_2120 9330b2333e85e061abda6758b39983ad 476 TIGRFAM TIGR03471 HpnJ: hopanoid biosynthesis associated radical SAM protein HpnJ 3 475 2.8E-263 T 12-10-2018 IPR017834 Hopanoid biosynthesis associated radical SAM protein HpnJ AFE_2120 9330b2333e85e061abda6758b39983ad 476 SUPERFAMILY SSF102114 163 411 2.75E-49 T 12-10-2018 AFE_2120 9330b2333e85e061abda6758b39983ad 476 Gene3D G3DSA:3.80.30.20 199 406 1.2E-27 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFE_1357 ecc00e5e9e906d12f1b941af426f24f1 383 Pfam PF00534 Glycosyl transferases group 1 198 356 1.7E-22 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1357 ecc00e5e9e906d12f1b941af426f24f1 383 Pfam PF13439 Glycosyltransferase Family 4 46 191 1.4E-7 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_1357 ecc00e5e9e906d12f1b941af426f24f1 383 SUPERFAMILY SSF53756 1 368 5.58E-54 T 12-10-2018 AFE_1357 ecc00e5e9e906d12f1b941af426f24f1 383 Gene3D G3DSA:3.40.50.2000 179 355 4.4E-29 T 12-10-2018 AFE_1472 165258703bd5ae6f639660f1719c5cc3 227 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 25 219 2.9E-43 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AFE_1472 165258703bd5ae6f639660f1719c5cc3 227 Gene3D G3DSA:3.90.850.10 5 227 1.2E-76 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFE_1472 165258703bd5ae6f639660f1719c5cc3 227 SUPERFAMILY SSF56529 19 226 7.06E-64 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFE_0460 987ca69adf7aeef2ea5d42cd2efb8e16 200 Hamap MF_01017 NAD(P)H dehydrogenase (quinone). 1 200 46.597 T 12-10-2018 IPR037513 NAD(P)H dehydrogenase (quinone), prokaryotic GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 AFE_0460 987ca69adf7aeef2ea5d42cd2efb8e16 200 Pfam PF03358 NADPH-dependent FMN reductase 13 143 2.2E-15 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFE_0460 987ca69adf7aeef2ea5d42cd2efb8e16 200 SUPERFAMILY SSF52218 3 199 5.63E-63 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFE_0460 987ca69adf7aeef2ea5d42cd2efb8e16 200 Gene3D G3DSA:3.40.50.360 1 200 5.4E-77 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFE_0460 987ca69adf7aeef2ea5d42cd2efb8e16 200 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 3 198 8.3E-91 T 12-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 AFE_0291 1f6a28490241b73964ea3a24fa59dafc 218 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 75 4.7E-18 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFE_0291 1f6a28490241b73964ea3a24fa59dafc 218 Gene3D G3DSA:1.20.1050.10 80 207 4.6E-22 T 12-10-2018 AFE_0291 1f6a28490241b73964ea3a24fa59dafc 218 Pfam PF13410 Glutathione S-transferase, C-terminal domain 118 164 8.4E-7 T 12-10-2018 AFE_0291 1f6a28490241b73964ea3a24fa59dafc 218 Gene3D G3DSA:3.40.30.10 1 79 9.0E-24 T 12-10-2018 AFE_0291 1f6a28490241b73964ea3a24fa59dafc 218 SUPERFAMILY SSF52833 1 101 6.01E-25 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0291 1f6a28490241b73964ea3a24fa59dafc 218 SUPERFAMILY SSF47616 78 195 3.14E-22 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily AFE_2662 83b8cba3ce567b4f74b22eb7c2f94a33 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 77 6.2E-20 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFE_2662 83b8cba3ce567b4f74b22eb7c2f94a33 104 SUPERFAMILY SSF54909 1 97 1.72E-26 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFE_2662 83b8cba3ce567b4f74b22eb7c2f94a33 104 Gene3D G3DSA:3.30.70.100 2 103 1.2E-29 T 12-10-2018 AFE_0036 18b6803f528d3a350dd488b4dd809015 555 Pfam PF12848 ABC transporter 230 306 8.8E-12 T 12-10-2018 IPR032781 ABC-transporter extension domain AFE_0036 18b6803f528d3a350dd488b4dd809015 555 SMART SM00382 348 526 5.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0036 18b6803f528d3a350dd488b4dd809015 555 SMART SM00382 31 242 2.7E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0036 18b6803f528d3a350dd488b4dd809015 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_0036 18b6803f528d3a350dd488b4dd809015 555 SUPERFAMILY SSF52540 302 522 1.58E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0036 18b6803f528d3a350dd488b4dd809015 555 Pfam PF00005 ABC transporter 22 191 1.5E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0036 18b6803f528d3a350dd488b4dd809015 555 Gene3D G3DSA:3.40.50.300 286 552 1.5E-71 T 12-10-2018 AFE_0036 18b6803f528d3a350dd488b4dd809015 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 553 1.4E-288 T 12-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 AFE_0036 18b6803f528d3a350dd488b4dd809015 555 SUPERFAMILY SSF52540 8 236 2.84E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0036 18b6803f528d3a350dd488b4dd809015 555 Gene3D G3DSA:3.40.50.300 1 285 1.0E-78 T 12-10-2018 AFE_0036 18b6803f528d3a350dd488b4dd809015 555 Pfam PF00005 ABC transporter 340 473 2.5E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_1798 fa12c6661f1804d801e431cfe86dc044 185 Pfam PF03729 Short repeat of unknown function (DUF308) 82 148 2.4E-4 T 12-10-2018 IPR005325 Protein of unknown function DUF308, membrane AFE_1798 fa12c6661f1804d801e431cfe86dc044 185 Pfam PF03729 Short repeat of unknown function (DUF308) 27 79 3.4E-6 T 12-10-2018 IPR005325 Protein of unknown function DUF308, membrane AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 Gene3D G3DSA:1.10.10.10 163 238 2.4E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 Gene3D G3DSA:1.10.10.10 243 316 3.9E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 Pfam PF04539 Sigma-70 region 3 170 238 9.9E-9 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 PRINTS PR00046 Major sigma-70 factor signature 138 146 3.4E-20 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 PRINTS PR00046 Major sigma-70 factor signature 262 274 3.4E-20 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 PRINTS PR00046 Major sigma-70 factor signature 114 127 3.4E-20 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 PRINTS PR00046 Major sigma-70 factor signature 283 298 3.4E-20 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 PRINTS PR00046 Major sigma-70 factor signature 298 309 3.4E-20 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 SUPERFAMILY SSF88659 221 313 2.8E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 Pfam PF04542 Sigma-70 region 2 89 159 9.3E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 Pfam PF00140 Sigma-70 factor, region 1.2 51 82 1.4E-11 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 Gene3D G3DSA:1.10.601.10 28 159 2.0E-40 T 12-10-2018 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 114 127 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 SUPERFAMILY SSF88946 51 160 6.93E-41 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 Pfam PF04545 Sigma-70, region 4 258 311 3.8E-12 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 85 312 9.1E-30 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFE_1833 b1faa4b6b1829067f9cde3a233c1ab01 316 SUPERFAMILY SSF88659 163 233 1.22E-7 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFE_1034 36c3d704ad43bda0538c26060a173592 501 Pfam PF07282 Putative transposase DNA-binding domain 370 436 2.6E-15 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFE_3114 2e0c94b819fc9699b3965e1bd0bdfc1e 121 SUPERFAMILY SSF75169 2 107 4.71E-13 T 12-10-2018 IPR027396 DsrEFH-like AFE_3114 2e0c94b819fc9699b3965e1bd0bdfc1e 121 Gene3D G3DSA:3.40.1260.10 2 118 1.2E-13 T 12-10-2018 IPR027396 DsrEFH-like AFE_2853 7583a5a494c05dc748bdc4ae37bf8521 247 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 247 104.548 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFE_2853 7583a5a494c05dc748bdc4ae37bf8521 247 Gene3D G3DSA:1.10.1270.20 164 247 3.8E-31 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFE_2853 7583a5a494c05dc748bdc4ae37bf8521 247 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 220 2.9E-56 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFE_2853 7583a5a494c05dc748bdc4ae37bf8521 247 PIRSF PIRSF000386 1 246 3.7E-92 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFE_2853 7583a5a494c05dc748bdc4ae37bf8521 247 SUPERFAMILY SSF75217 1 242 1.94E-91 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFE_2853 7583a5a494c05dc748bdc4ae37bf8521 247 Gene3D G3DSA:3.40.1280.10 1 163 1.1E-60 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFE_2853 7583a5a494c05dc748bdc4ae37bf8521 247 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 231 1.4E-87 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFE_2934 2d261b4fc65768d397dee2536d998e4f 254 SUPERFAMILY SSF46894 152 250 1.87E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFE_2934 2d261b4fc65768d397dee2536d998e4f 254 Pfam PF00486 Transcriptional regulatory protein, C terminal 172 248 8.6E-17 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2934 2d261b4fc65768d397dee2536d998e4f 254 SMART SM00862 172 248 2.1E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2934 2d261b4fc65768d397dee2536d998e4f 254 SUPERFAMILY SSF52172 36 151 7.46E-5 T 12-10-2018 IPR011006 CheY-like superfamily AFE_2934 2d261b4fc65768d397dee2536d998e4f 254 Gene3D G3DSA:1.10.10.10 147 250 8.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_3217 9de23c2c8149db408524a3ca8fb3a151 180 SMART SM00852 19 163 2.1E-28 T 12-10-2018 IPR001453 MoaB/Mog domain AFE_3217 9de23c2c8149db408524a3ca8fb3a151 180 Gene3D G3DSA:3.40.980.10 8 176 6.8E-49 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFE_3217 9de23c2c8149db408524a3ca8fb3a151 180 PIRSF PIRSF006443 2 171 9.6E-61 T 12-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 AFE_3217 9de23c2c8149db408524a3ca8fb3a151 180 Pfam PF00994 Probable molybdopterin binding domain 19 160 1.6E-33 T 12-10-2018 IPR001453 MoaB/Mog domain AFE_3217 9de23c2c8149db408524a3ca8fb3a151 180 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 13 173 5.8E-78 T 12-10-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 AFE_3217 9de23c2c8149db408524a3ca8fb3a151 180 SUPERFAMILY SSF53218 11 165 1.7E-42 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFE_3217 9de23c2c8149db408524a3ca8fb3a151 180 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 17 158 5.5E-34 T 12-10-2018 IPR001453 MoaB/Mog domain AFE_2449 b2b1455239ba361bacdeeb3bbd93e9ef 79 Pfam PF00462 Glutaredoxin 4 59 2.9E-14 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFE_2449 b2b1455239ba361bacdeeb3bbd93e9ef 79 Gene3D G3DSA:3.40.30.10 2 76 1.6E-14 T 12-10-2018 AFE_2449 b2b1455239ba361bacdeeb3bbd93e9ef 79 SUPERFAMILY SSF52833 1 70 5.1E-14 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 40 89 2.0E-17 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 PRINTS PR00974 Ribosomal protein S18 family signature 47 57 3.0E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 PRINTS PR00974 Ribosomal protein S18 family signature 65 79 3.0E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 PRINTS PR00974 Ribosomal protein S18 family signature 57 64 3.0E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 PRINTS PR00974 Ribosomal protein S18 family signature 79 89 3.0E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 Pfam PF01084 Ribosomal protein S18 38 87 1.2E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 TIGRFAM TIGR00165 S18: ribosomal protein bS18 24 91 9.4E-33 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 SUPERFAMILY SSF46911 21 91 1.31E-26 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 21 92 19.672 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 Gene3D G3DSA:4.10.640.10 12 92 2.5E-24 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2823 51fdb530f671fc7f69626944a3ca37ae 92 ProSitePatterns PS00057 Ribosomal protein S18 signature. 40 63 - T 12-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0301 24cd884af3a5084809f38be0e1551b12 147 SUPERFAMILY SSF48013 4 138 2.49E-33 T 12-10-2018 IPR035926 NusB-like superfamily AFE_0301 24cd884af3a5084809f38be0e1551b12 147 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 4 138 20.698 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 AFE_0301 24cd884af3a5084809f38be0e1551b12 147 Gene3D G3DSA:1.10.940.10 1 142 3.3E-42 T 12-10-2018 IPR035926 NusB-like superfamily AFE_0301 24cd884af3a5084809f38be0e1551b12 147 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 6 136 2.6E-38 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 AFE_0301 24cd884af3a5084809f38be0e1551b12 147 Pfam PF01029 NusB family 9 134 3.0E-29 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFE_2115 41efb4a63749d961c9a959276bedbbc2 367 Gene3D G3DSA:3.20.20.70 24 295 2.1E-31 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2115 41efb4a63749d961c9a959276bedbbc2 367 Pfam PF11946 Domain of unknown function (DUF3463) 195 331 6.0E-58 T 12-10-2018 IPR022563 Domain of unknown function DUF3463 AFE_2115 41efb4a63749d961c9a959276bedbbc2 367 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 321 2.7E-160 T 12-10-2018 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH AFE_2115 41efb4a63749d961c9a959276bedbbc2 367 SUPERFAMILY SSF102114 23 310 2.35E-51 T 12-10-2018 AFE_2115 41efb4a63749d961c9a959276bedbbc2 367 Pfam PF04055 Radical SAM superfamily 34 186 6.9E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_2964 4658891940155f7ac1fb23a12bb2cfb1 249 SUPERFAMILY SSF53335 23 167 2.66E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2964 4658891940155f7ac1fb23a12bb2cfb1 249 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 27 159 7.3E-18 T 12-10-2018 IPR006342 Methyltransferase FkbM AFE_2964 4658891940155f7ac1fb23a12bb2cfb1 249 Gene3D G3DSA:3.40.50.150 12 187 3.5E-16 T 12-10-2018 AFE_2964 4658891940155f7ac1fb23a12bb2cfb1 249 Pfam PF05050 Methyltransferase FkbM domain 29 190 6.0E-21 T 12-10-2018 IPR006342 Methyltransferase FkbM AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 112 550 1.1E-103 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 Gene3D G3DSA:1.20.210.10 94 604 1.4E-141 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 SUPERFAMILY SSF81442 107 597 4.84E-128 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 459 478 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 509 530 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 277 296 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 327 348 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 150 173 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 219 231 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 373 388 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 396 417 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 431 449 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 178 202 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3149 146da540ba9bdabc153a04a923e0c7c4 627 PRINTS PR01165 Cytochrome c oxidase subunit I signature 248 266 1.1E-54 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_1951 e55e6b72633807e6ef44ad7a653e819d 191 SUPERFAMILY SSF49777 37 186 1.83E-48 T 12-10-2018 IPR036610 PEBP-like superfamily AFE_1951 e55e6b72633807e6ef44ad7a653e819d 191 Gene3D G3DSA:3.90.280.10 35 188 9.8E-57 T 12-10-2018 IPR036610 PEBP-like superfamily AFE_1951 e55e6b72633807e6ef44ad7a653e819d 191 Pfam PF01161 Phosphatidylethanolamine-binding protein 50 186 3.1E-39 T 12-10-2018 IPR008914 Phosphatidylethanolamine-binding protein AFE_1951 e55e6b72633807e6ef44ad7a653e819d 191 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 54 183 3.7E-36 T 12-10-2018 IPR005247 YbhB/YbcL AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 Pfam PF13365 Trypsin-like peptidase domain 126 259 3.4E-30 T 12-10-2018 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 Gene3D G3DSA:2.30.42.10 415 506 1.7E-16 T 12-10-2018 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 Gene3D G3DSA:2.30.42.10 298 397 1.6E-23 T 12-10-2018 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 SUPERFAMILY SSF50494 60 290 2.1E-60 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 Gene3D G3DSA:2.40.10.120 60 291 1.9E-74 T 12-10-2018 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 Pfam PF13180 PDZ domain 298 387 1.2E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 61 500 4.4E-134 T 12-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 SUPERFAMILY SSF50156 435 504 6.97E-14 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 PRINTS PR00834 HtrA/DegQ protease family signature 135 147 3.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 PRINTS PR00834 HtrA/DegQ protease family signature 156 176 3.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 PRINTS PR00834 HtrA/DegQ protease family signature 196 220 3.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 PRINTS PR00834 HtrA/DegQ protease family signature 230 247 3.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 PRINTS PR00834 HtrA/DegQ protease family signature 252 269 3.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 PRINTS PR00834 HtrA/DegQ protease family signature 338 350 3.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 SMART SM00228 415 494 9.8E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 SMART SM00228 298 380 3.6E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_2849 7434104ba92445d0c028bbe3aab7d1fb 506 SUPERFAMILY SSF50156 256 380 3.55E-22 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFE_0959 a340b8fe86ef90657d5e59fae4fc158e 193 SUPERFAMILY SSF53474 1 190 1.02E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_0959 a340b8fe86ef90657d5e59fae4fc158e 193 Pfam PF02230 Phospholipase/Carboxylesterase 1 191 5.4E-41 T 12-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 AFE_0959 a340b8fe86ef90657d5e59fae4fc158e 193 Gene3D G3DSA:3.40.50.1820 1 191 1.8E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_1447 7815cc57b29030cbb76b216af812dd8e 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 186 6.1E-66 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 AFE_1447 7815cc57b29030cbb76b216af812dd8e 186 Gene3D G3DSA:1.10.132.20 13 183 7.9E-65 T 12-10-2018 AFE_1447 7815cc57b29030cbb76b216af812dd8e 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 26.452 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 AFE_1447 7815cc57b29030cbb76b216af812dd8e 186 Gene3D G3DSA:3.30.1360.40 32 106 7.9E-65 T 12-10-2018 AFE_1447 7815cc57b29030cbb76b216af812dd8e 186 Pfam PF01765 Ribosome recycling factor 21 184 1.8E-58 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 AFE_1447 7815cc57b29030cbb76b216af812dd8e 186 SUPERFAMILY SSF55194 6 185 1.02E-65 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 AFE_1610 eb1a691031bfef729634cf1c4bdc5b7d 109 SUPERFAMILY SSF46689 5 100 5.73E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_1610 eb1a691031bfef729634cf1c4bdc5b7d 109 Gene3D G3DSA:1.10.10.10 1 68 5.8E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1610 eb1a691031bfef729634cf1c4bdc5b7d 109 Pfam PF01527 Transposase 6 88 2.3E-9 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 AFE_3089 64e3686aa3e2663daf068ae03ced4f1d 127 Gene3D G3DSA:2.40.40.20 2 127 1.5E-49 T 12-10-2018 AFE_3089 64e3686aa3e2663daf068ae03ced4f1d 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 4 121 1.4E-44 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFE_3089 64e3686aa3e2663daf068ae03ced4f1d 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 6 122 7.0E-25 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFE_3089 64e3686aa3e2663daf068ae03ced4f1d 127 PIRSF PIRSF006246 2 126 2.3E-46 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFE_3089 64e3686aa3e2663daf068ae03ced4f1d 127 SUPERFAMILY SSF50692 3 117 3.23E-44 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFE_3089 64e3686aa3e2663daf068ae03ced4f1d 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 61.945 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFE_3089 64e3686aa3e2663daf068ae03ced4f1d 127 Pfam PF02261 Aspartate decarboxylase 4 115 6.7E-46 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFE_0175 341586ac6b6f8726873b4205ac36f8a0 102 Pfam PF10084 Uncharacterized protein conserved in bacteria (DUF2322) 12 73 2.8E-6 T 12-10-2018 IPR016755 Uncharacterised conserved protein UCP019302 AFE_1851 55826f213d9b4fce33a749da85e71f95 214 Gene3D G3DSA:3.90.550.10 3 210 8.8E-34 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_1851 55826f213d9b4fce33a749da85e71f95 214 Pfam PF00535 Glycosyl transferase family 2 11 136 9.4E-22 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFE_1851 55826f213d9b4fce33a749da85e71f95 214 SUPERFAMILY SSF53448 9 207 6.11E-37 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0601 aa8063000086de7cdf09dcb533e708e0 501 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 60 444 1.9E-84 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 AFE_0601 aa8063000086de7cdf09dcb533e708e0 501 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 6 482 20.328 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 AFE_0601 aa8063000086de7cdf09dcb533e708e0 501 Pfam PF00795 Carbon-nitrogen hydrolase 221 465 6.2E-27 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFE_0601 aa8063000086de7cdf09dcb533e708e0 501 SUPERFAMILY SSF56317 216 476 5.1E-39 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFE_0601 aa8063000086de7cdf09dcb533e708e0 501 Gene3D G3DSA:3.60.110.10 218 458 3.5E-22 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFE_2114 bae39ae1da701298292a07f1c3161bcd 219 Gene3D G3DSA:3.10.450.50 70 183 2.3E-30 T 12-10-2018 AFE_2114 bae39ae1da701298292a07f1c3161bcd 219 Pfam PF05494 MlaC protein 69 209 7.3E-36 T 12-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC AFE_2114 bae39ae1da701298292a07f1c3161bcd 219 TIGRFAM TIGR03481 HpnM: hopanoid biosynthesis associated membrane protein HpnM 11 217 8.0E-81 T 12-10-2018 IPR017842 Hopanoid biosynthesis-associated membrane protein HpnM AFE_2114 bae39ae1da701298292a07f1c3161bcd 219 Gene3D G3DSA:1.10.10.640 85 208 2.3E-30 T 12-10-2018 AFE_0469 824606600c184a32469029ad99f5b0c4 241 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 15 225 32.125 T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AFE_0469 824606600c184a32469029ad99f5b0c4 241 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 19 222 1.6E-54 T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AFE_0469 824606600c184a32469029ad99f5b0c4 241 Gene3D G3DSA:3.40.50.150 12 226 1.8E-63 T 12-10-2018 AFE_0469 824606600c184a32469029ad99f5b0c4 241 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 22 220 3.1E-50 T 12-10-2018 AFE_0469 824606600c184a32469029ad99f5b0c4 241 SUPERFAMILY SSF53335 27 188 4.26E-35 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2627 4539db06c3219671d16db0905031f1a4 417 Gene3D G3DSA:1.10.645.20 4 417 9.0E-176 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2627 4539db06c3219671d16db0905031f1a4 417 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 417 7.1E-185 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2627 4539db06c3219671d16db0905031f1a4 417 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 12-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2627 4539db06c3219671d16db0905031f1a4 417 SUPERFAMILY SSF56762 16 417 8.63E-139 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2627 4539db06c3219671d16db0905031f1a4 417 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 417 50.053 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2627 4539db06c3219671d16db0905031f1a4 417 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 417 3.7E-123 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2072 e6d7b71d3528012b5c7809eade799654 722 SUPERFAMILY SSF48452 468 707 2.23E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2072 e6d7b71d3528012b5c7809eade799654 722 Gene3D G3DSA:1.20.58.2200 668 722 8.8E-17 T 12-10-2018 IPR038440 FimV, C-terminal domain superfamily AFE_2072 e6d7b71d3528012b5c7809eade799654 722 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 679 722 2.1E-19 T 12-10-2018 IPR020011 Motility protein FimV, C-terminal AFE_2072 e6d7b71d3528012b5c7809eade799654 722 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 171 238 4.3E-16 T 12-10-2018 IPR020012 Motility protein FimV, N-terminal AFE_2072 e6d7b71d3528012b5c7809eade799654 722 Gene3D G3DSA:1.25.40.10 466 540 7.3E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0529 b6b89eae5899d5dbc2b0b9f20f5931f4 128 SUPERFAMILY SSF52821 10 128 2.62E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_0529 b6b89eae5899d5dbc2b0b9f20f5931f4 128 Gene3D G3DSA:3.40.250.10 1 128 3.5E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_0529 b6b89eae5899d5dbc2b0b9f20f5931f4 128 SMART SM00450 21 125 7.3E-24 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_0529 b6b89eae5899d5dbc2b0b9f20f5931f4 128 ProSitePatterns PS00380 Rhodanese signature 1. 45 56 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 AFE_0529 b6b89eae5899d5dbc2b0b9f20f5931f4 128 Pfam PF00581 Rhodanese-like domain 24 121 8.3E-18 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_0564 bba588669243f7010d58533799d43cd7 91 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 17.307 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0564 bba588669243f7010d58533799d43cd7 91 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 1.8E-21 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0564 bba588669243f7010d58533799d43cd7 91 Pfam PF01192 RNA polymerase Rpb6 8 58 7.4E-17 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFE_0564 bba588669243f7010d58533799d43cd7 91 SUPERFAMILY SSF63562 1 66 2.09E-23 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFE_0564 bba588669243f7010d58533799d43cd7 91 Gene3D G3DSA:3.90.940.10 1 86 8.2E-25 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFE_0564 bba588669243f7010d58533799d43cd7 91 SMART SM01409 8 60 1.8E-18 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFE_0288 94c27317c9363b00e9447edd732189ca 784 Gene3D G3DSA:3.20.20.210 6 548 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFE_0288 94c27317c9363b00e9447edd732189ca 784 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 455 777 9.8E-154 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFE_0288 94c27317c9363b00e9447edd732189ca 784 PIRSF PIRSF000382 1 184 2.6E-67 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFE_0288 94c27317c9363b00e9447edd732189ca 784 PIRSF PIRSF000382 193 784 2.3E-258 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFE_0288 94c27317c9363b00e9447edd732189ca 784 SUPERFAMILY SSF51726 5 418 2.09E-112 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFE_0288 94c27317c9363b00e9447edd732189ca 784 Gene3D G3DSA:3.20.20.210 413 780 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFE_0288 94c27317c9363b00e9447edd732189ca 784 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 782 37.769 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFE_0288 94c27317c9363b00e9447edd732189ca 784 SUPERFAMILY SSF51726 420 781 7.33E-121 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFE_0288 94c27317c9363b00e9447edd732189ca 784 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 338 1.7E-123 T 12-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFE_0521 9e6fd35ea1c5bc1909443570c2e8adbc 114 Gene3D G3DSA:3.30.1390.10 11 114 8.2E-39 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFE_0521 9e6fd35ea1c5bc1909443570c2e8adbc 114 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 32 109 7.7E-32 T 12-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 AFE_0521 9e6fd35ea1c5bc1909443570c2e8adbc 114 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 21 109 25.694 T 12-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS AFE_0521 9e6fd35ea1c5bc1909443570c2e8adbc 114 SUPERFAMILY SSF54736 29 113 3.98E-29 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFE_0172 4fe96c1309a39427b04786f22628472a 297 SUPERFAMILY SSF46785 3 113 2.96E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0172 4fe96c1309a39427b04786f22628472a 297 Gene3D G3DSA:3.40.190.290 92 296 8.8E-36 T 12-10-2018 AFE_0172 4fe96c1309a39427b04786f22628472a 297 SUPERFAMILY SSF53850 89 294 3.08E-32 T 12-10-2018 AFE_0172 4fe96c1309a39427b04786f22628472a 297 Pfam PF03466 LysR substrate binding domain 90 294 5.4E-37 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_0172 4fe96c1309a39427b04786f22628472a 297 Gene3D G3DSA:1.10.10.10 1 82 5.8E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0172 4fe96c1309a39427b04786f22628472a 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.7E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0412 b53bc661d7e79c104d2daf1878c0d1c8 58 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 1 58 1.8E-20 T 12-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 AFE_0412 b53bc661d7e79c104d2daf1878c0d1c8 58 Gene3D G3DSA:3.30.2310.20 1 58 2.8E-23 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFE_0412 b53bc661d7e79c104d2daf1878c0d1c8 58 SUPERFAMILY SSF143011 4 57 9.81E-14 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFE_0412 b53bc661d7e79c104d2daf1878c0d1c8 58 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 1 58 2.0E-23 T 12-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 AFE_1605 23e0cd75d41290ef4ae928ba92616fd7 309 Pfam PF00005 ABC transporter 16 159 1.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_1605 23e0cd75d41290ef4ae928ba92616fd7 309 SUPERFAMILY SSF52540 3 219 2.39E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1605 23e0cd75d41290ef4ae928ba92616fd7 309 Gene3D G3DSA:3.40.50.300 2 223 5.5E-69 T 12-10-2018 AFE_1605 23e0cd75d41290ef4ae928ba92616fd7 309 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_1605 23e0cd75d41290ef4ae928ba92616fd7 309 SMART SM00382 24 205 4.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1605 23e0cd75d41290ef4ae928ba92616fd7 309 Pfam PF13732 Domain of unknown function (DUF4162) 211 299 6.9E-7 T 12-10-2018 IPR025302 Domain of unknown function DUF4162 AFE_1538 e2a4f80c6ed56ad9e126b4e4f2c24efa 69 Gene3D G3DSA:2.40.50.240 1 67 1.4E-31 T 12-10-2018 IPR024044 NifT/FixU barrel-like domain superfamily AFE_1538 e2a4f80c6ed56ad9e126b4e4f2c24efa 69 TIGRFAM TIGR02934 nifT_nitrog: probable nitrogen fixation protein FixT 1 67 1.4E-34 T 12-10-2018 IPR009727 NifT/FixU GO:0009399 AFE_1538 e2a4f80c6ed56ad9e126b4e4f2c24efa 69 Pfam PF06988 NifT/FixU protein 1 64 1.8E-31 T 12-10-2018 IPR009727 NifT/FixU GO:0009399 AFE_1538 e2a4f80c6ed56ad9e126b4e4f2c24efa 69 SUPERFAMILY SSF159203 1 67 2.75E-26 T 12-10-2018 IPR024044 NifT/FixU barrel-like domain superfamily AFE_0582 3004e28c6b24a970d4c738a9423c4e75 65 Pfam PF10049 Protein of unknown function (DUF2283) 3 50 7.1E-20 T 12-10-2018 IPR019270 Protein of unknown function DUF2283 AFE_2341 24c82ccce9cedb987fcbee40c10c11e4 207 Gene3D G3DSA:3.90.950.10 1 198 1.2E-66 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFE_2341 24c82ccce9cedb987fcbee40c10c11e4 207 Pfam PF01725 Ham1 family 4 191 5.4E-50 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 AFE_2341 24c82ccce9cedb987fcbee40c10c11e4 207 Hamap MF_01405 dITP/XTP pyrophosphatase. 2 196 41.622 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 AFE_2341 24c82ccce9cedb987fcbee40c10c11e4 207 SUPERFAMILY SSF52972 1 195 2.54E-62 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFE_2341 24c82ccce9cedb987fcbee40c10c11e4 207 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 193 3.7E-49 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 AFE_2639 d77b7d5aac980fa168b23a4e04a838e2 380 Pfam PF00268 Ribonucleotide reductase, small chain 60 347 1.7E-81 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2639 d77b7d5aac980fa168b23a4e04a838e2 380 Gene3D G3DSA:1.10.620.20 36 373 4.8E-112 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 AFE_2639 d77b7d5aac980fa168b23a4e04a838e2 380 PIRSF PIRSF000355 34 380 5.6E-132 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFE_2639 d77b7d5aac980fa168b23a4e04a838e2 380 SUPERFAMILY SSF47240 42 373 9.83E-95 T 12-10-2018 IPR009078 Ferritin-like superfamily AFE_2820 fa0719339239029b7a2c2393556dd3ee 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2820 fa0719339239029b7a2c2393556dd3ee 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 23.681 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2820 fa0719339239029b7a2c2393556dd3ee 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 145 2.0E-40 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2820 fa0719339239029b7a2c2393556dd3ee 148 SUPERFAMILY SSF55658 1 56 2.09E-17 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal AFE_2820 fa0719339239029b7a2c2393556dd3ee 148 SUPERFAMILY SSF55653 60 146 3.4E-22 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily AFE_2820 fa0719339239029b7a2c2393556dd3ee 148 Gene3D G3DSA:3.10.430.100 61 147 2.3E-23 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily AFE_2820 fa0719339239029b7a2c2393556dd3ee 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 1.5E-21 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2820 fa0719339239029b7a2c2393556dd3ee 148 Gene3D G3DSA:3.40.5.10 1 50 4.7E-22 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2820 fa0719339239029b7a2c2393556dd3ee 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 3.4E-22 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal AFE_0906 b06fd03583959d85f8421d9335012e30 384 Pfam PF13432 Tetratricopeptide repeat 49 90 6.4E-6 T 12-10-2018 AFE_0906 b06fd03583959d85f8421d9335012e30 384 SUPERFAMILY SSF48452 40 240 1.42E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0906 b06fd03583959d85f8421d9335012e30 384 Gene3D G3DSA:1.25.40.10 179 250 1.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0906 b06fd03583959d85f8421d9335012e30 384 Gene3D G3DSA:1.25.40.10 40 174 6.3E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0906 b06fd03583959d85f8421d9335012e30 384 Pfam PF13174 Tetratricopeptide repeat 110 141 0.062 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1359 2745f11bf8043b92bd4b8df99fd1b067 134 Gene3D G3DSA:3.30.460.10 18 134 2.3E-14 T 12-10-2018 AFE_1359 2745f11bf8043b92bd4b8df99fd1b067 134 SUPERFAMILY SSF81301 33 133 2.73E-15 T 12-10-2018 AFE_1359 2745f11bf8043b92bd4b8df99fd1b067 134 Pfam PF01909 Nucleotidyltransferase domain 33 110 4.1E-10 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFE_1482 b85f676a074f311afbada33710398b00 203 Pfam PF01152 Bacterial-like globin 68 180 3.6E-16 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 AFE_1482 b85f676a074f311afbada33710398b00 203 SUPERFAMILY SSF46458 83 183 4.8E-17 T 12-10-2018 IPR009050 Globin-like superfamily AFE_1482 b85f676a074f311afbada33710398b00 203 Gene3D G3DSA:1.10.490.10 59 203 1.8E-39 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFE_2384 d40187e8721c432f44e76612df5ce417 290 SUPERFAMILY SSF53850 30 196 2.02E-9 T 12-10-2018 AFE_2384 d40187e8721c432f44e76612df5ce417 290 Gene3D G3DSA:3.40.190.10 28 225 7.9E-11 T 12-10-2018 AFE_2384 d40187e8721c432f44e76612df5ce417 290 Gene3D G3DSA:3.40.190.10 92 196 7.9E-11 T 12-10-2018 AFE_2384 d40187e8721c432f44e76612df5ce417 290 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 16 245 1.4E-35 T 12-10-2018 AFE_2670 c60910673edb2599a5e381d2eb6ef9bf 78 Pfam PF00830 Ribosomal L28 family 3 62 9.4E-30 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2670 c60910673edb2599a5e381d2eb6ef9bf 78 Gene3D G3DSA:2.30.170.40 2 78 2.0E-35 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2670 c60910673edb2599a5e381d2eb6ef9bf 78 SUPERFAMILY SSF143800 2 77 9.42E-33 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2670 c60910673edb2599a5e381d2eb6ef9bf 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 22.055 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2670 c60910673edb2599a5e381d2eb6ef9bf 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 2.2E-29 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2190 8b746920f7f62c626c34558536dc1095 267 Gene3D G3DSA:1.10.3720.10 17 265 2.9E-51 T 12-10-2018 IPR035906 MetI-like superfamily AFE_2190 8b746920f7f62c626c34558536dc1095 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 219 1.1E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFE_2190 8b746920f7f62c626c34558536dc1095 267 SUPERFAMILY SSF161098 15 253 5.76E-43 T 12-10-2018 IPR035906 MetI-like superfamily AFE_2058 f8738c176f1587245ed1a6e53bd1cdb2 111 Pfam PF02699 Preprotein translocase subunit 25 99 9.9E-26 T 12-10-2018 IPR003849 Preprotein translocase YajC AFE_2058 f8738c176f1587245ed1a6e53bd1cdb2 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 23 43 3.8E-15 T 12-10-2018 IPR003849 Preprotein translocase YajC AFE_2058 f8738c176f1587245ed1a6e53bd1cdb2 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 61 79 3.8E-15 T 12-10-2018 IPR003849 Preprotein translocase YajC AFE_2058 f8738c176f1587245ed1a6e53bd1cdb2 111 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 21 100 6.9E-25 T 12-10-2018 IPR003849 Preprotein translocase YajC AFE_2058 f8738c176f1587245ed1a6e53bd1cdb2 111 SMART SM01323 21 103 8.8E-37 T 12-10-2018 IPR003849 Preprotein translocase YajC AFE_0815 c1c298c2b5487b50b428967fac9f0a06 590 SUPERFAMILY SSF81340 7 439 4.05E-99 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 AFE_0815 c1c298c2b5487b50b428967fac9f0a06 590 Gene3D G3DSA:3.10.580.10 446 579 1.3E-7 T 12-10-2018 AFE_0815 c1c298c2b5487b50b428967fac9f0a06 590 Pfam PF00654 Voltage gated chloride channel 68 421 2.3E-86 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0815 c1c298c2b5487b50b428967fac9f0a06 590 SUPERFAMILY SSF54631 452 576 4.45E-8 T 12-10-2018 AFE_0815 c1c298c2b5487b50b428967fac9f0a06 590 PRINTS PR00762 Chloride channel signature 82 99 2.2E-19 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0815 c1c298c2b5487b50b428967fac9f0a06 590 PRINTS PR00762 Chloride channel signature 337 357 2.2E-19 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0815 c1c298c2b5487b50b428967fac9f0a06 590 PRINTS PR00762 Chloride channel signature 390 409 2.2E-19 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0815 c1c298c2b5487b50b428967fac9f0a06 590 PRINTS PR00762 Chloride channel signature 162 181 2.2E-19 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0815 c1c298c2b5487b50b428967fac9f0a06 590 Gene3D G3DSA:1.10.3080.10 2 440 2.3E-108 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 AFE_1919 9bd4472fb751c9b3524189e90959452d 572 Gene3D G3DSA:3.40.50.300 14 178 3.0E-98 T 12-10-2018 AFE_1919 9bd4472fb751c9b3524189e90959452d 572 Gene3D G3DSA:1.10.8.60 9 239 3.0E-98 T 12-10-2018 AFE_1919 9bd4472fb751c9b3524189e90959452d 572 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 4 354 5.9E-118 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 AFE_1919 9bd4472fb751c9b3524189e90959452d 572 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 234 364 6.6E-17 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 AFE_1919 9bd4472fb751c9b3524189e90959452d 572 SUPERFAMILY SSF52540 35 223 1.45E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1919 9bd4472fb751c9b3524189e90959452d 572 Gene3D G3DSA:1.20.272.10 243 360 4.3E-22 T 12-10-2018 AFE_1919 9bd4472fb751c9b3524189e90959452d 572 Pfam PF13177 DNA polymerase III, delta subunit 21 179 2.4E-41 T 12-10-2018 AFE_1919 9bd4472fb751c9b3524189e90959452d 572 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 42 60 1.8E-6 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFE_1919 9bd4472fb751c9b3524189e90959452d 572 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 125 143 1.8E-6 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 AFE_1919 9bd4472fb751c9b3524189e90959452d 572 SMART SM00382 38 180 2.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1919 9bd4472fb751c9b3524189e90959452d 572 SUPERFAMILY SSF48019 247 363 3.06E-16 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFE_2803 190242144e647bfe373d1318dd55a85f 180 Gene3D G3DSA:3.40.50.360 1 180 3.3E-38 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFE_2803 190242144e647bfe373d1318dd55a85f 180 SUPERFAMILY SSF52218 1 155 2.35E-32 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFE_2803 190242144e647bfe373d1318dd55a85f 180 Pfam PF03358 NADPH-dependent FMN reductase 1 136 4.5E-27 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFE_0985 1f8bf134eafe852ae26ceae6a5166f51 200 PIRSF PIRSF000239 1 199 1.3E-64 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFE_0985 1f8bf134eafe852ae26ceae6a5166f51 200 Gene3D G3DSA:3.40.30.10 1 196 9.3E-74 T 12-10-2018 AFE_0985 1f8bf134eafe852ae26ceae6a5166f51 200 SUPERFAMILY SSF52833 3 198 1.49E-64 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0985 1f8bf134eafe852ae26ceae6a5166f51 200 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 193 6.8E-12 T 12-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFE_0985 1f8bf134eafe852ae26ceae6a5166f51 200 Pfam PF00578 AhpC/TSA family 5 139 2.8E-33 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFE_1791 e9718a04a45d9b7b7aaddf1aca4cc46d 177 PIRSF PIRSF019345 1 173 1.9E-47 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFE_1791 e9718a04a45d9b7b7aaddf1aca4cc46d 177 Gene3D G3DSA:1.10.10.10 73 172 2.5E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1791 e9718a04a45d9b7b7aaddf1aca4cc46d 177 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 8 166 5.8E-30 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFE_1791 e9718a04a45d9b7b7aaddf1aca4cc46d 177 SUPERFAMILY SSF46785 7 74 2.45E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1791 e9718a04a45d9b7b7aaddf1aca4cc46d 177 SUPERFAMILY SSF46785 78 152 1.36E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1791 e9718a04a45d9b7b7aaddf1aca4cc46d 177 Pfam PF04079 Segregation and condensation complex subunit ScpB 7 161 1.0E-39 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFE_0247 e0a2d75a2b6eec3626e28a906dc2c3ad 298 Pfam PF01435 Peptidase family M48 91 291 3.1E-38 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFE_0247 e0a2d75a2b6eec3626e28a906dc2c3ad 298 Gene3D G3DSA:3.30.2010.10 78 170 4.4E-29 T 12-10-2018 AFE_0221 ec992f34ab4fe285b852a45e3d684c4a 206 SUPERFAMILY SSF52833 11 110 4.15E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0221 ec992f34ab4fe285b852a45e3d684c4a 206 Gene3D G3DSA:3.40.30.10 11 199 2.4E-69 T 12-10-2018 AFE_0221 ec992f34ab4fe285b852a45e3d684c4a 206 Gene3D G3DSA:1.20.1050.10 89 191 2.4E-69 T 12-10-2018 AFE_0221 ec992f34ab4fe285b852a45e3d684c4a 206 Pfam PF13410 Glutathione S-transferase, C-terminal domain 123 180 1.4E-8 T 12-10-2018 AFE_0221 ec992f34ab4fe285b852a45e3d684c4a 206 Pfam PF13417 Glutathione S-transferase, N-terminal domain 13 87 2.6E-19 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFE_0221 ec992f34ab4fe285b852a45e3d684c4a 206 SUPERFAMILY SSF47616 82 205 1.53E-23 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 1.6E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 1.6E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 1.6E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 1.6E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 SUPERFAMILY SSF55261 290 421 5.67E-40 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 SUPERFAMILY SSF50249 1 105 1.12E-31 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 Gene3D G3DSA:3.30.1360.30 273 422 8.7E-196 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 Pfam PF02938 GAD domain 309 408 3.4E-27 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 584 8.3E-244 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 Gene3D G3DSA:2.40.50.140 1 106 5.6E-33 T 12-10-2018 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 Gene3D G3DSA:3.30.930.10 117 584 8.7E-196 T 12-10-2018 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 586 33.671 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 1.5E-13 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 560 5.1E-108 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0056 fc3969ccc28ea6676d6538c370edd59b 596 SUPERFAMILY SSF55681 110 586 2.11E-107 T 12-10-2018 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 SUPERFAMILY SSF55124 8 140 1.96E-31 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 470 486 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 Gene3D G3DSA:3.90.480.10 73 396 1.9E-71 T 12-10-2018 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 Gene3D G3DSA:3.30.413.10 140 331 1.9E-71 T 12-10-2018 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 PRINTS PR00397 Sirohaem Fe-binding site signature 422 440 8.9E-9 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 PRINTS PR00397 Sirohaem Fe-binding site signature 470 488 8.9E-9 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 70 131 9.0E-17 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 345 409 4.4E-12 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 SUPERFAMILY SSF56014 421 549 2.88E-31 T 12-10-2018 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 165 320 1.3E-46 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 Gene3D G3DSA:3.30.413.10 418 552 1.8E-32 T 12-10-2018 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 3 562 54.399 T 12-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 SUPERFAMILY SSF56014 141 336 2.49E-56 T 12-10-2018 AFE_3122 c727a451e8ae7c37a61a87acceae5693 563 SUPERFAMILY SSF55124 338 412 7.85E-16 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFE_2548 e86b7f92a223c0546ed42766c00bd928 132 SUPERFAMILY SSF75169 13 132 5.72E-18 T 12-10-2018 IPR027396 DsrEFH-like AFE_2548 e86b7f92a223c0546ed42766c00bd928 132 Pfam PF02635 DsrE/DsrF-like family 13 132 9.2E-16 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFE_2548 e86b7f92a223c0546ed42766c00bd928 132 Gene3D G3DSA:3.40.1260.10 3 132 3.7E-30 T 12-10-2018 IPR027396 DsrEFH-like AFE_2103 684377997f3ee80e0c3110e1c59c9012 364 Gene3D G3DSA:2.40.50.100 60 203 1.9E-55 T 12-10-2018 AFE_2103 684377997f3ee80e0c3110e1c59c9012 364 SUPERFAMILY SSF111369 50 284 3.01E-49 T 12-10-2018 AFE_2103 684377997f3ee80e0c3110e1c59c9012 364 Gene3D G3DSA:2.40.30.170 54 270 1.9E-55 T 12-10-2018 AFE_2103 684377997f3ee80e0c3110e1c59c9012 364 Gene3D G3DSA:1.10.287.470 95 168 1.9E-55 T 12-10-2018 AFE_2103 684377997f3ee80e0c3110e1c59c9012 364 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 281 7.2E-16 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_2103 684377997f3ee80e0c3110e1c59c9012 364 Gene3D G3DSA:2.40.420.20 271 362 4.6E-13 T 12-10-2018 AFE_2103 684377997f3ee80e0c3110e1c59c9012 364 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 36 361 1.8E-65 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Pfam PF00690 Cation transporter/ATPase, N-terminus 15 64 1.6E-7 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Pfam PF00122 E1-E2 ATPase 105 298 6.3E-44 T 12-10-2018 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 SUPERFAMILY SSF81665 11 853 2.48E-80 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Gene3D G3DSA:1.20.1110.10 638 841 2.6E-107 T 12-10-2018 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 209 340 1.7E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 562 680 1.8E-31 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 321 327 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 SUPERFAMILY SSF81653 108 215 9.42E-24 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Pfam PF00702 haloacid dehalogenase-like hydrolase 315 606 5.1E-28 T 12-10-2018 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 624 649 1.7E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 592 608 1.7E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 564 580 1.7E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 447 465 1.7E-19 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Gene3D G3DSA:3.40.1110.10 392 498 2.6E-107 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Gene3D G3DSA:3.40.1110.10 329 341 3.8E-83 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Gene3D G3DSA:1.20.1110.10 48 315 3.8E-83 T 12-10-2018 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 SMART SM00831 4 70 0.001 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 SUPERFAMILY SSF56784 317 677 1.7E-57 T 12-10-2018 IPR036412 HAD-like superfamily AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Pfam PF00689 Cation transporting ATPase, C-terminus 676 847 5.5E-19 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Gene3D G3DSA:3.40.50.1000 499 637 2.6E-107 T 12-10-2018 IPR023214 HAD superfamily AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Gene3D G3DSA:3.40.50.1000 316 328 3.8E-83 T 12-10-2018 IPR023214 HAD superfamily AFE_2944 53a918b8a3a77a362b99341955bb5825 858 Gene3D G3DSA:2.70.150.10 14 221 3.8E-83 T 12-10-2018 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 491 502 2.1E-38 T 12-10-2018 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 592 611 2.1E-38 T 12-10-2018 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 154 168 2.1E-38 T 12-10-2018 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 319 333 2.1E-38 T 12-10-2018 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 616 628 2.1E-38 T 12-10-2018 AFE_2944 53a918b8a3a77a362b99341955bb5825 858 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 513 523 2.1E-38 T 12-10-2018 AFE_0358 9fa9fc4547a2eef4d7b60c1ff2424658 224 SUPERFAMILY SSF47781 15 90 1.07E-8 T 12-10-2018 IPR010994 RuvA domain 2-like AFE_0358 9fa9fc4547a2eef4d7b60c1ff2424658 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 12-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site AFE_0358 9fa9fc4547a2eef4d7b60c1ff2424658 224 Gene3D G3DSA:3.40.140.10 103 223 1.3E-40 T 12-10-2018 AFE_0358 9fa9fc4547a2eef4d7b60c1ff2424658 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 222 1.0E-69 T 12-10-2018 IPR001405 Uncharacterised protein family UPF0758 AFE_0358 9fa9fc4547a2eef4d7b60c1ff2424658 224 Pfam PF04002 RadC-like JAB domain 104 222 1.6E-41 T 12-10-2018 IPR025657 RadC-like JAB domain AFE_0358 9fa9fc4547a2eef4d7b60c1ff2424658 224 SUPERFAMILY SSF102712 123 198 1.06E-5 T 12-10-2018 AFE_2671 11f0937945f98e338ce65f8f4b714e27 372 Pfam PF00793 DAHP synthetase I family 101 347 2.8E-43 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFE_2671 11f0937945f98e338ce65f8f4b714e27 372 Gene3D G3DSA:3.20.20.70 85 356 1.7E-69 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2671 11f0937945f98e338ce65f8f4b714e27 372 SUPERFAMILY SSF51569 17 360 1.28E-73 T 12-10-2018 AFE_2671 11f0937945f98e338ce65f8f4b714e27 372 Gene3D G3DSA:3.30.70.1140 1 84 5.4E-7 T 12-10-2018 AFE_3221 01bc6053f5aa44869030b0e60f22c805 303 SUPERFAMILY SSF144083 235 297 3.53E-5 T 12-10-2018 AFE_3221 01bc6053f5aa44869030b0e60f22c805 303 Pfam PF01544 CorA-like Mg2+ transporter protein 17 296 9.9E-28 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFE_3221 01bc6053f5aa44869030b0e60f22c805 303 SUPERFAMILY SSF143865 14 229 9.42E-15 T 12-10-2018 AFE_3221 01bc6053f5aa44869030b0e60f22c805 303 Gene3D G3DSA:3.30.460.20 4 120 6.5E-7 T 12-10-2018 AFE_3221 01bc6053f5aa44869030b0e60f22c805 303 Gene3D G3DSA:1.20.58.340 223 300 2.0E-7 T 12-10-2018 AFE_1406 4fa145caec5caae64c0505a0766b050a 316 SUPERFAMILY SSF53613 12 309 8.89E-58 T 12-10-2018 IPR029056 Ribokinase-like AFE_1406 4fa145caec5caae64c0505a0766b050a 316 Pfam PF00294 pfkB family carbohydrate kinase 12 300 3.1E-42 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFE_1406 4fa145caec5caae64c0505a0766b050a 316 Gene3D G3DSA:3.40.1190.20 4 308 7.9E-113 T 12-10-2018 IPR029056 Ribokinase-like AFE_1406 4fa145caec5caae64c0505a0766b050a 316 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 6 309 4.0E-116 T 12-10-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 AFE_1406 4fa145caec5caae64c0505a0766b050a 316 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 74 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFE_2476 e6ca0e6c006c75648e866d746b64cacc 30 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 8.1E-5 T 12-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 AFE_2476 e6ca0e6c006c75648e866d746b64cacc 30 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 2.7E-7 T 12-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 AFE_3053 3a6caab52cc6eca5f00dc6f5fff1dc92 267 SUPERFAMILY SSF52540 23 224 8.57E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3053 3a6caab52cc6eca5f00dc6f5fff1dc92 267 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 182 265 7.2E-33 T 12-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal AFE_3053 3a6caab52cc6eca5f00dc6f5fff1dc92 267 Gene3D G3DSA:3.40.50.300 20 187 3.6E-30 T 12-10-2018 AFE_3053 3a6caab52cc6eca5f00dc6f5fff1dc92 267 Pfam PF07728 AAA domain (dynein-related subfamily) 36 169 6.1E-32 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Gene3D G3DSA:3.90.1110.10 329 450 1.3E-33 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Pfam PF00562 RNA polymerase Rpb2, domain 6 726 1283 8.1E-162 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Pfam PF04563 RNA polymerase beta subunit 26 508 1.3E-40 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Gene3D G3DSA:2.40.270.10 1057 1261 5.9E-86 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Gene3D G3DSA:2.40.270.10 799 841 2.4E-7 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Pfam PF04561 RNA polymerase Rpb2, domain 2 367 463 1.2E-13 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Pfam PF04561 RNA polymerase Rpb2, domain 2 176 231 9.9E-7 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 SUPERFAMILY SSF64484 12 1361 0.0 T 12-10-2018 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Pfam PF04560 RNA polymerase Rpb2, domain 7 1285 1359 2.8E-26 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Gene3D G3DSA:2.40.50.100 723 797 3.9E-29 T 12-10-2018 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Pfam PF04565 RNA polymerase Rpb2, domain 3 522 589 2.6E-31 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1085 1097 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Gene3D G3DSA:3.90.1100.10 451 641 3.2E-71 T 12-10-2018 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1358 0.0 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Pfam PF10385 RNA polymerase beta subunit external 1 domain 600 665 1.7E-23 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Gene3D G3DSA:3.90.1800.10 1271 1322 9.5E-11 T 12-10-2018 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Gene3D G3DSA:2.40.50.150 842 964 1.2E-43 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Gene3D G3DSA:3.90.1100.10 652 722 2.5E-20 T 12-10-2018 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Gene3D G3DSA:3.90.1100.10 18 179 5.2E-52 T 12-10-2018 AFE_0320 0c66a803d69831d66f0c86fdaee852f6 1362 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1361 12.413 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFE_2797 63032cbf34929db1e728795b0a354c35 136 SUPERFAMILY SSF51182 30 129 7.47E-8 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_2797 63032cbf34929db1e728795b0a354c35 136 Gene3D G3DSA:2.60.120.10 3 131 1.8E-8 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_2062 9881097cc83c3cbe00d3ff9bd758d9c7 197 SUPERFAMILY SSF54631 45 172 6.13E-13 T 12-10-2018 AFE_2062 9881097cc83c3cbe00d3ff9bd758d9c7 197 Gene3D G3DSA:3.10.580.10 35 176 6.7E-12 T 12-10-2018 AFE_2062 9881097cc83c3cbe00d3ff9bd758d9c7 197 Pfam PF00571 CBS domain 44 91 6.0E-9 T 12-10-2018 IPR000644 CBS domain AFE_1519 7339fd388de4bc3c8a75732103da5bb8 114 Gene3D G3DSA:3.10.20.30 1 114 9.1E-34 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_1519 7339fd388de4bc3c8a75732103da5bb8 114 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFE_1519 7339fd388de4bc3c8a75732103da5bb8 114 SUPERFAMILY SSF54292 1 113 5.09E-13 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFE_1519 7339fd388de4bc3c8a75732103da5bb8 114 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 16 105 3.5E-10 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFE_3118 701571494ac1c7cc4406a585b8124c34 379 Gene3D G3DSA:3.50.50.60 3 313 8.6E-79 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_3118 701571494ac1c7cc4406a585b8124c34 379 Gene3D G3DSA:3.50.50.60 114 257 8.6E-79 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_3118 701571494ac1c7cc4406a585b8124c34 379 SUPERFAMILY SSF51905 1 150 3.4E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_3118 701571494ac1c7cc4406a585b8124c34 379 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.8E-5 T 12-10-2018 AFE_3118 701571494ac1c7cc4406a585b8124c34 379 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.8E-5 T 12-10-2018 AFE_3118 701571494ac1c7cc4406a585b8124c34 379 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 271 6.7E-16 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_3118 701571494ac1c7cc4406a585b8124c34 379 SUPERFAMILY SSF51905 117 248 1.67E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2601 701571494ac1c7cc4406a585b8124c34 379 Gene3D G3DSA:3.50.50.60 3 313 8.6E-79 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2601 701571494ac1c7cc4406a585b8124c34 379 Gene3D G3DSA:3.50.50.60 114 257 8.6E-79 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2601 701571494ac1c7cc4406a585b8124c34 379 SUPERFAMILY SSF51905 1 150 3.4E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2601 701571494ac1c7cc4406a585b8124c34 379 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.8E-5 T 12-10-2018 AFE_2601 701571494ac1c7cc4406a585b8124c34 379 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.8E-5 T 12-10-2018 AFE_2601 701571494ac1c7cc4406a585b8124c34 379 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 271 6.7E-16 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_2601 701571494ac1c7cc4406a585b8124c34 379 SUPERFAMILY SSF51905 117 248 1.67E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0483 6dc537521e36a284bcb9b4fdc2119369 231 Gene3D G3DSA:3.40.50.300 4 228 1.2E-61 T 12-10-2018 AFE_0483 6dc537521e36a284bcb9b4fdc2119369 231 SMART SM00382 35 227 1.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0483 6dc537521e36a284bcb9b4fdc2119369 231 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_0483 6dc537521e36a284bcb9b4fdc2119369 231 SUPERFAMILY SSF52540 6 227 4.09E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0483 6dc537521e36a284bcb9b4fdc2119369 231 Pfam PF00005 ABC transporter 27 174 1.6E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0339 ef5de2ab7bfe5bc9d42ae5516e4a1e89 180 SUPERFAMILY SSF55282 4 179 4.47E-74 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0339 ef5de2ab7bfe5bc9d42ae5516e4a1e89 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 42.608 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0339 ef5de2ab7bfe5bc9d42ae5516e4a1e89 180 Gene3D G3DSA:3.30.1440.10 1 179 1.2E-74 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0339 ef5de2ab7bfe5bc9d42ae5516e4a1e89 180 Pfam PF00673 ribosomal L5P family C-terminus 85 178 1.7E-38 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0339 ef5de2ab7bfe5bc9d42ae5516e4a1e89 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 12-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0339 ef5de2ab7bfe5bc9d42ae5516e4a1e89 180 Pfam PF00281 Ribosomal protein L5 25 81 1.5E-26 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0339 ef5de2ab7bfe5bc9d42ae5516e4a1e89 180 PIRSF PIRSF002161 1 180 7.0E-60 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_2447 758210ce28297b34097524d56263d826 131 Pfam PF03625 Domain of unknown function DUF302 36 99 1.2E-27 T 12-10-2018 IPR005180 Domain of unknown function DUF302 AFE_2447 758210ce28297b34097524d56263d826 131 Gene3D G3DSA:3.30.310.70 6 129 6.0E-45 T 12-10-2018 IPR035923 TT1751-like domain superfamily AFE_2447 758210ce28297b34097524d56263d826 131 PIRSF PIRSF021774 1 131 1.6E-42 T 12-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 AFE_2447 758210ce28297b34097524d56263d826 131 SUPERFAMILY SSF103247 6 127 2.22E-36 T 12-10-2018 IPR035923 TT1751-like domain superfamily AFE_2540 ec0643707ce9769b966de7abe2fe980b 303 SUPERFAMILY SSF55681 2 203 1.66E-34 T 12-10-2018 AFE_2540 ec0643707ce9769b966de7abe2fe980b 303 Gene3D G3DSA:3.30.930.10 1 211 4.8E-28 T 12-10-2018 AFE_0566 c6e52cdbac3e1293dc9e7451395fc72f 129 SUPERFAMILY SSF55298 3 126 2.2E-39 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFE_0566 c6e52cdbac3e1293dc9e7451395fc72f 129 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 101 119 - T 12-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 AFE_0566 c6e52cdbac3e1293dc9e7451395fc72f 129 Pfam PF01042 Endoribonuclease L-PSP 9 124 5.5E-37 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 AFE_0566 c6e52cdbac3e1293dc9e7451395fc72f 129 Gene3D G3DSA:3.30.1330.40 3 128 3.7E-45 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFE_0566 c6e52cdbac3e1293dc9e7451395fc72f 129 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 5 123 2.0E-43 T 12-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 AFE_2320 0f8cb22428ed636cc63de6cb445a6888 194 SUPERFAMILY SSF53098 5 178 1.71E-41 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_2320 0f8cb22428ed636cc63de6cb445a6888 194 Pfam PF00929 Exonuclease 9 169 5.0E-27 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFE_2320 0f8cb22428ed636cc63de6cb445a6888 194 Gene3D G3DSA:3.30.420.10 1 181 1.7E-65 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_2320 0f8cb22428ed636cc63de6cb445a6888 194 Hamap MF_00045 Oligoribonuclease [orn]. 3 180 39.839 T 12-10-2018 IPR022894 Oligoribonuclease GO:0000175 AFE_2320 0f8cb22428ed636cc63de6cb445a6888 194 SMART SM00479 7 179 3.5E-16 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFE_2028 54888e44435ffb38a99a6294381a0e1d 801 Gene3D G3DSA:2.120.10.90 581 784 9.4E-13 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFE_2028 54888e44435ffb38a99a6294381a0e1d 801 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 87 546 1.0E-123 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_2028 54888e44435ffb38a99a6294381a0e1d 801 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 59 801 32.23 T 12-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_2028 54888e44435ffb38a99a6294381a0e1d 801 Gene3D G3DSA:3.30.1360.40 292 410 9.1E-176 T 12-10-2018 AFE_2028 54888e44435ffb38a99a6294381a0e1d 801 SUPERFAMILY SSF101904 583 799 3.27E-36 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFE_2028 54888e44435ffb38a99a6294381a0e1d 801 SMART SM00434 66 540 3.1E-197 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_2028 54888e44435ffb38a99a6294381a0e1d 801 Gene3D G3DSA:1.10.268.10 448 533 9.1E-176 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFE_2028 54888e44435ffb38a99a6294381a0e1d 801 Gene3D G3DSA:3.90.199.10 87 561 9.1E-176 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AFE_2028 54888e44435ffb38a99a6294381a0e1d 801 SUPERFAMILY SSF56719 86 561 2.22E-139 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFE_2028 54888e44435ffb38a99a6294381a0e1d 801 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 68 797 2.4E-215 T 12-10-2018 AFE_2754 314730b6708694d1db592ac1669d8292 189 SUPERFAMILY SSF53335 3 181 3.75E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2754 314730b6708694d1db592ac1669d8292 189 PIRSF PIRSF004553 2 183 2.7E-42 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 AFE_2754 314730b6708694d1db592ac1669d8292 189 Pfam PF03602 Conserved hypothetical protein 95 4 181 4.5E-45 T 12-10-2018 AFE_2754 314730b6708694d1db592ac1669d8292 189 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 181 2.5E-39 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 AFE_2754 314730b6708694d1db592ac1669d8292 189 Gene3D G3DSA:3.40.50.150 1 186 5.3E-53 T 12-10-2018 AFE_1966 a963a6ef9ed1fdd75a9f3c4f6b99f23f 333 SUPERFAMILY SSF51735 1 332 1.66E-87 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1966 a963a6ef9ed1fdd75a9f3c4f6b99f23f 333 Gene3D G3DSA:3.40.50.720 6 315 1.9E-93 T 12-10-2018 AFE_1966 a963a6ef9ed1fdd75a9f3c4f6b99f23f 333 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 236 1.1E-54 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFE_1966 a963a6ef9ed1fdd75a9f3c4f6b99f23f 333 PRINTS PR01713 Nucleotide sugar epimerase signature 31 47 2.9E-26 T 12-10-2018 AFE_1966 a963a6ef9ed1fdd75a9f3c4f6b99f23f 333 PRINTS PR01713 Nucleotide sugar epimerase signature 218 233 2.9E-26 T 12-10-2018 AFE_1966 a963a6ef9ed1fdd75a9f3c4f6b99f23f 333 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 2.9E-26 T 12-10-2018 AFE_1966 a963a6ef9ed1fdd75a9f3c4f6b99f23f 333 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 2.9E-26 T 12-10-2018 AFE_1966 a963a6ef9ed1fdd75a9f3c4f6b99f23f 333 Gene3D G3DSA:3.90.25.10 182 327 1.9E-93 T 12-10-2018 AFE_1529 49b509294b85bebbcb6dff1fe26bd5ce 499 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 374 467 3.1E-18 T 12-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis AFE_1529 49b509294b85bebbcb6dff1fe26bd5ce 499 SUPERFAMILY SSF53146 364 476 1.26E-29 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AFE_1529 49b509294b85bebbcb6dff1fe26bd5ce 499 Gene3D G3DSA:3.20.20.70 45 347 1.1E-29 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1529 49b509294b85bebbcb6dff1fe26bd5ce 499 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 59 70 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_1529 49b509294b85bebbcb6dff1fe26bd5ce 499 TIGRFAM TIGR01290 nifB: nitrogenase cofactor biosynthesis protein NifB 31 470 2.0E-210 T 12-10-2018 IPR005980 Nitrogenase cofactor biosynthesis protein NifB GO:0009108|GO:0009399 AFE_1529 49b509294b85bebbcb6dff1fe26bd5ce 499 SUPERFAMILY SSF102114 47 261 6.67E-35 T 12-10-2018 AFE_1529 49b509294b85bebbcb6dff1fe26bd5ce 499 Gene3D G3DSA:3.30.420.130 359 477 1.5E-25 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AFE_1529 49b509294b85bebbcb6dff1fe26bd5ce 499 Pfam PF04055 Radical SAM superfamily 59 237 5.8E-27 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_1783 3895fc843829b67974d2e96b9e745380 383 Pfam PF00696 Amino acid kinase family 11 246 4.4E-41 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFE_1783 3895fc843829b67974d2e96b9e745380 383 PIRSF PIRSF000729 6 380 1.8E-118 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AFE_1783 3895fc843829b67974d2e96b9e745380 383 Hamap MF_00456 Glutamate 5-kinase [proB]. 11 274 33.878 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_1783 3895fc843829b67974d2e96b9e745380 383 PRINTS PR00474 Glutamate 5-kinase family signature 128 149 3.7E-38 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_1783 3895fc843829b67974d2e96b9e745380 383 PRINTS PR00474 Glutamate 5-kinase family signature 160 187 3.7E-38 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_1783 3895fc843829b67974d2e96b9e745380 383 PRINTS PR00474 Glutamate 5-kinase family signature 48 62 3.7E-38 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_1783 3895fc843829b67974d2e96b9e745380 383 PRINTS PR00474 Glutamate 5-kinase family signature 221 241 3.7E-38 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_1783 3895fc843829b67974d2e96b9e745380 383 Gene3D G3DSA:2.30.130.10 278 379 5.2E-24 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 AFE_1783 3895fc843829b67974d2e96b9e745380 383 SUPERFAMILY SSF53633 11 268 6.81E-66 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_1783 3895fc843829b67974d2e96b9e745380 383 ProSitePatterns PS00902 Glutamate 5-kinase signature. 219 236 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_1783 3895fc843829b67974d2e96b9e745380 383 Gene3D G3DSA:3.40.1160.10 2 277 1.3E-86 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_1783 3895fc843829b67974d2e96b9e745380 383 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 378 8.8E-117 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_1783 3895fc843829b67974d2e96b9e745380 383 Pfam PF01472 PUA domain 290 359 2.1E-17 T 12-10-2018 IPR002478 PUA domain GO:0003723 AFE_1783 3895fc843829b67974d2e96b9e745380 383 SUPERFAMILY SSF88697 288 378 3.36E-16 T 12-10-2018 IPR015947 PUA-like superfamily AFE_1783 3895fc843829b67974d2e96b9e745380 383 SMART SM00359 289 375 5.6E-8 T 12-10-2018 IPR002478 PUA domain GO:0003723 AFE_2423 0467ac603b0feaebb49851674b7e291b 163 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 1 77 1.5E-23 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_2423 0467ac603b0feaebb49851674b7e291b 163 SUPERFAMILY SSF51344 1 77 7.32E-19 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_2423 0467ac603b0feaebb49851674b7e291b 163 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 4 80 5.0E-19 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_2423 0467ac603b0feaebb49851674b7e291b 163 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 1 127 3.5E-31 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_2423 0467ac603b0feaebb49851674b7e291b 163 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 1 126 16.524 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_2423 0467ac603b0feaebb49851674b7e291b 163 Gene3D G3DSA:2.60.15.10 1 125 6.1E-30 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_0603 360a449794e2854351645eb31819861d 274 Pfam PF00005 ABC transporter 21 166 1.6E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0603 360a449794e2854351645eb31819861d 274 SUPERFAMILY SSF52540 2 226 4.88E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0603 360a449794e2854351645eb31819861d 274 Gene3D G3DSA:3.40.50.300 5 251 8.9E-58 T 12-10-2018 AFE_0603 360a449794e2854351645eb31819861d 274 SMART SM00382 30 215 3.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 Gene3D G3DSA:3.40.50.300 324 502 6.8E-62 T 12-10-2018 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 SMART SM00464 20 212 3.0E-46 T 12-10-2018 IPR003111 Lon, substrate-binding domain AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 684 703 6.7E-52 T 12-10-2018 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 714 733 6.7E-52 T 12-10-2018 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 366 385 6.7E-52 T 12-10-2018 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 606 622 6.7E-52 T 12-10-2018 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 737 755 6.7E-52 T 12-10-2018 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 SUPERFAMILY SSF52540 321 593 6.8E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 Gene3D G3DSA:1.20.58.1480 131 255 2.7E-34 T 12-10-2018 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 Hamap MF_01973 Lon protease [lon]. 21 783 65.746 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 SMART SM00382 358 504 4.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 581 783 5.5E-86 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 SUPERFAMILY SSF88697 20 210 1.17E-42 T 12-10-2018 IPR015947 PUA-like superfamily AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 PIRSF PIRSF001174 5 786 2.6E-285 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 SUPERFAMILY SSF54211 606 780 3.79E-52 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 687 695 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 Gene3D G3DSA:3.30.230.10 605 788 2.2E-78 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 20 210 1.1E-36 T 12-10-2018 IPR003111 Lon, substrate-binding domain AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 TIGRFAM TIGR00763 lon: endopeptidase La 22 781 4.3E-275 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 Gene3D G3DSA:1.10.8.60 503 595 3.2E-28 T 12-10-2018 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 362 501 1.7E-20 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_0872 4a6ac0eae5eac02e15016c5df58a0dff 788 Gene3D G3DSA:2.30.130.40 5 128 2.2E-31 T 12-10-2018 AFE_0629 f4a074877ccfd4bd2998378e523a4539 219 Gene3D G3DSA:3.30.70.260 125 196 1.1E-72 T 12-10-2018 AFE_0629 f4a074877ccfd4bd2998378e523a4539 219 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 31.584 T 12-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AFE_0629 f4a074877ccfd4bd2998378e523a4539 219 SUPERFAMILY SSF75445 127 198 7.85E-22 T 12-10-2018 AFE_0629 f4a074877ccfd4bd2998378e523a4539 219 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 50 212 5.2E-53 T 12-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AFE_0629 f4a074877ccfd4bd2998378e523a4539 219 SUPERFAMILY SSF100950 1 146 4.49E-43 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFE_0629 f4a074877ccfd4bd2998378e523a4539 219 Gene3D G3DSA:3.40.50.1360 7 207 1.1E-72 T 12-10-2018 AFE_0629 f4a074877ccfd4bd2998378e523a4539 219 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 214 6.2E-64 T 12-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AFE_0364 8ef3cbd051618583a48e8aba494da4b8 194 Pfam PF00156 Phosphoribosyl transferase domain 23 175 4.1E-19 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFE_0364 8ef3cbd051618583a48e8aba494da4b8 194 SUPERFAMILY SSF53271 23 192 2.36E-40 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFE_0364 8ef3cbd051618583a48e8aba494da4b8 194 Gene3D G3DSA:3.40.50.2020 12 193 5.6E-49 T 12-10-2018 AFE_2718 e76fc4e9f67be4715ddd03d2dc929467 591 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 48 588 4.0E-142 T 12-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 AFE_2718 e76fc4e9f67be4715ddd03d2dc929467 591 SUPERFAMILY SSF51998 49 582 1.86E-160 T 12-10-2018 AFE_2718 e76fc4e9f67be4715ddd03d2dc929467 591 Gene3D G3DSA:3.20.70.20 61 590 1.0E-111 T 12-10-2018 AFE_2718 e76fc4e9f67be4715ddd03d2dc929467 591 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 49 582 2.1E-174 T 12-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 AFE_0241 c46d5bf2c03c1554c0e3ea7383f102fd 171 PIRSF PIRSF029256 5 157 9.4E-65 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 AFE_0241 c46d5bf2c03c1554c0e3ea7383f102fd 171 Pfam PF00588 SpoU rRNA Methylase family 6 145 2.8E-31 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFE_0241 c46d5bf2c03c1554c0e3ea7383f102fd 171 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 6 156 3.0E-58 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 AFE_0241 c46d5bf2c03c1554c0e3ea7383f102fd 171 SUPERFAMILY SSF75217 6 154 1.96E-45 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFE_0241 c46d5bf2c03c1554c0e3ea7383f102fd 171 Gene3D G3DSA:3.40.1280.10 2 160 3.4E-65 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFE_0241 c46d5bf2c03c1554c0e3ea7383f102fd 171 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 6 155 33.504 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 AFE_3001 6d6512c7ff3207286ff7605227fb8d6f 90 Gene3D G3DSA:3.30.70.260 10 86 5.1E-7 T 12-10-2018 AFE_3001 6d6512c7ff3207286ff7605227fb8d6f 90 SUPERFAMILY SSF55021 12 83 7.75E-7 T 12-10-2018 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 SMART SM00984 315 419 2.6E-39 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 Gene3D G3DSA:1.20.5.100 200 230 2.2E-16 T 12-10-2018 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 184 4.1E-57 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 316 418 6.8E-29 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 292 8.2E-34 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 SUPERFAMILY SSF52413 304 429 8.63E-34 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 PIRSF PIRSF500134 2 434 3.2E-155 T 12-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 3 415 3.1E-147 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 PIRSF PIRSF000124 1 434 1.2E-131 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 SUPERFAMILY SSF48179 200 293 1.46E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 Gene3D G3DSA:3.40.50.720 1 198 1.3E-68 T 12-10-2018 AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 SUPERFAMILY SSF51735 2 191 5.3E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0618 213a24cbb12a3c0d208ed26d2730296b 434 Gene3D G3DSA:3.40.50.720 231 434 5.6E-68 T 12-10-2018 AFE_0005 e96b23edc454b69838e8ec3d61c5b4b5 170 SMART SM00972 109 167 1.2E-23 T 12-10-2018 IPR007893 Spore coat protein U AFE_0005 e96b23edc454b69838e8ec3d61c5b4b5 170 Pfam PF05229 Spore Coat Protein U domain 35 167 2.3E-35 T 12-10-2018 IPR007893 Spore coat protein U AFE_2875 d854495092c44c7a4a5d09764491fb38 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 7.3E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2875 d854495092c44c7a4a5d09764491fb38 307 Gene3D G3DSA:1.10.10.10 5 90 3.2E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2875 d854495092c44c7a4a5d09764491fb38 307 Gene3D G3DSA:3.40.190.10 165 266 2.1E-66 T 12-10-2018 AFE_2875 d854495092c44c7a4a5d09764491fb38 307 SUPERFAMILY SSF46785 5 85 3.11E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2875 d854495092c44c7a4a5d09764491fb38 307 Pfam PF03466 LysR substrate binding domain 90 295 2.6E-45 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_2875 d854495092c44c7a4a5d09764491fb38 307 Gene3D G3DSA:3.40.190.10 93 293 2.1E-66 T 12-10-2018 AFE_2875 d854495092c44c7a4a5d09764491fb38 307 SUPERFAMILY SSF53850 91 299 7.96E-48 T 12-10-2018 AFE_0468 9a8cb664cc6239a2a0dd40fa3890b1b4 250 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 235 3.0E-65 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFE_0468 9a8cb664cc6239a2a0dd40fa3890b1b4 250 Gene3D G3DSA:3.40.1210.10 1 250 7.6E-90 T 12-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFE_0468 9a8cb664cc6239a2a0dd40fa3890b1b4 250 SUPERFAMILY SSF64167 3 249 5.62E-81 T 12-10-2018 AFE_0468 9a8cb664cc6239a2a0dd40fa3890b1b4 250 Pfam PF01975 Survival protein SurE 5 184 1.5E-57 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFE_0468 9a8cb664cc6239a2a0dd40fa3890b1b4 250 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 250 38.957 T 12-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AFE_1943 ea0d3656785d7b5bdc9b0f3705700216 225 Pfam PF13098 Thioredoxin-like domain 73 221 6.8E-24 T 12-10-2018 IPR012336 Thioredoxin-like fold AFE_1943 ea0d3656785d7b5bdc9b0f3705700216 225 SUPERFAMILY SSF52833 41 221 6.8E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1943 ea0d3656785d7b5bdc9b0f3705700216 225 Gene3D G3DSA:3.40.30.10 69 225 2.5E-24 T 12-10-2018 AFE_2159 72c71bbdf991ece5601019228e4333b4 113 SUPERFAMILY SSF57783 3 35 2.89E-12 T 12-10-2018 AFE_2159 72c71bbdf991ece5601019228e4333b4 113 SUPERFAMILY SSF82057 42 112 2.01E-25 T 12-10-2018 AFE_2159 72c71bbdf991ece5601019228e4333b4 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 111 3.0E-46 T 12-10-2018 IPR004624 PhnA protein AFE_2159 72c71bbdf991ece5601019228e4333b4 113 Gene3D G3DSA:2.30.30.40 43 113 3.5E-30 T 12-10-2018 AFE_2159 72c71bbdf991ece5601019228e4333b4 113 Pfam PF03831 PhnA domain 45 112 2.7E-29 T 12-10-2018 IPR013988 PhnA protein, C-terminal AFE_2159 72c71bbdf991ece5601019228e4333b4 113 Gene3D G3DSA:2.20.25.10 1 42 2.5E-15 T 12-10-2018 AFE_2159 72c71bbdf991ece5601019228e4333b4 113 Pfam PF08274 PhnA Zinc-Ribbon 4 32 3.7E-12 T 12-10-2018 IPR013987 PhnA protein, N-terminal AFE_0930 846c0ff69a8d523722f183020aef4377 281 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 135 276 2.2E-39 T 12-10-2018 IPR008136 CinA, C-terminal AFE_0930 846c0ff69a8d523722f183020aef4377 281 SUPERFAMILY SSF142433 132 280 4.32E-45 T 12-10-2018 IPR036653 CinA-like, C-terminal AFE_0930 846c0ff69a8d523722f183020aef4377 281 Gene3D G3DSA:3.90.950.20 123 280 4.3E-49 T 12-10-2018 IPR036653 CinA-like, C-terminal AFE_0930 846c0ff69a8d523722f183020aef4377 281 Pfam PF02464 Competence-damaged protein 134 277 2.5E-45 T 12-10-2018 IPR008136 CinA, C-terminal AFE_2660 a205fd54c0b7f1e829ec9f0c2f616455 188 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 5 187 4.5E-49 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 AFE_2660 a205fd54c0b7f1e829ec9f0c2f616455 188 Pfam PF00692 dUTPase 81 183 2.0E-6 T 12-10-2018 IPR029054 dUTPase-like AFE_2660 a205fd54c0b7f1e829ec9f0c2f616455 188 Gene3D G3DSA:2.70.40.10 1 159 4.2E-53 T 12-10-2018 IPR036157 dUTPase-like superfamily AFE_2660 a205fd54c0b7f1e829ec9f0c2f616455 188 SUPERFAMILY SSF51283 3 187 2.36E-52 T 12-10-2018 IPR036157 dUTPase-like superfamily AFE_2660 a205fd54c0b7f1e829ec9f0c2f616455 188 Hamap MF_00146 dCTP deaminase [dcd]. 1 188 28.41 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 AFE_2992 ea9bd2f536277365d690666846aa0065 498 SUPERFAMILY SSF53850 2 494 1.65E-81 T 12-10-2018 AFE_2992 ea9bd2f536277365d690666846aa0065 498 Gene3D G3DSA:3.10.105.10 244 463 3.2E-85 T 12-10-2018 AFE_2992 ea9bd2f536277365d690666846aa0065 498 Gene3D G3DSA:3.40.190.10 4 477 3.2E-85 T 12-10-2018 AFE_2992 ea9bd2f536277365d690666846aa0065 498 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 40 407 7.2E-55 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain AFE_2992 ea9bd2f536277365d690666846aa0065 498 Gene3D G3DSA:3.90.76.10 22 148 3.2E-85 T 12-10-2018 AFE_2992 ea9bd2f536277365d690666846aa0065 498 PIRSF PIRSF002741 1 494 3.3E-56 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFE_1505 8f86fdf2c2e1e993cc70f8e9eaf4937b 258 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 123 4.1E-6 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_1505 8f86fdf2c2e1e993cc70f8e9eaf4937b 258 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 134 166 5.7E-5 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_1505 8f86fdf2c2e1e993cc70f8e9eaf4937b 258 Gene3D G3DSA:2.160.10.10 82 200 3.6E-34 T 12-10-2018 AFE_1505 8f86fdf2c2e1e993cc70f8e9eaf4937b 258 Pfam PF06426 Serine acetyltransferase, N-terminal 14 50 1.7E-4 T 12-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 AFE_1505 8f86fdf2c2e1e993cc70f8e9eaf4937b 258 SUPERFAMILY SSF51161 17 183 3.74E-53 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFE_1505 8f86fdf2c2e1e993cc70f8e9eaf4937b 258 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 21 181 1.3E-74 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 AFE_1505 8f86fdf2c2e1e993cc70f8e9eaf4937b 258 Gene3D G3DSA:1.10.3130.10 5 81 3.1E-23 T 12-10-2018 AFE_1749 12e4d6dbe22f8689c5e1cde57eedc7a9 194 Pfam PF02586 SOS response associated peptidase (SRAP) 46 176 5.6E-32 T 12-10-2018 IPR003738 SOS response associated peptidase (SRAP) AFE_1749 12e4d6dbe22f8689c5e1cde57eedc7a9 194 Gene3D G3DSA:3.90.1680.10 14 187 4.4E-37 T 12-10-2018 IPR036590 SOS response associated peptidase-like AFE_1749 12e4d6dbe22f8689c5e1cde57eedc7a9 194 SUPERFAMILY SSF143081 46 187 2.09E-34 T 12-10-2018 IPR036590 SOS response associated peptidase-like AFE_0519 0d717edfb7c009bb7ebd2daf93b0c04b 491 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 6 460 1.3E-125 T 12-10-2018 IPR003846 Uncharacterised protein family UPF0061 AFE_0519 0d717edfb7c009bb7ebd2daf93b0c04b 491 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 4 477 45.777 T 12-10-2018 IPR003846 Uncharacterised protein family UPF0061 AFE_3192 76ab4300e84afda7ac617e0c1cfe0dc0 751 SUPERFAMILY SSF53335 90 402 2.67E-63 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_3192 76ab4300e84afda7ac617e0c1cfe0dc0 751 SUPERFAMILY SSF49299 713 745 3.66E-5 T 12-10-2018 IPR035986 PKD domain superfamily AFE_3192 76ab4300e84afda7ac617e0c1cfe0dc0 751 Gene3D G3DSA:3.40.50.150 91 421 1.5E-69 T 12-10-2018 AFE_3192 76ab4300e84afda7ac617e0c1cfe0dc0 751 Pfam PF01555 DNA methylase 124 387 1.1E-39 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 AFE_3192 76ab4300e84afda7ac617e0c1cfe0dc0 751 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 123 135 4.8E-21 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFE_3192 76ab4300e84afda7ac617e0c1cfe0dc0 751 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 179 198 4.8E-21 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFE_3192 76ab4300e84afda7ac617e0c1cfe0dc0 751 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 336 358 4.8E-21 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFE_3192 76ab4300e84afda7ac617e0c1cfe0dc0 751 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 359 373 4.8E-21 T 12-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFE_2678 4c2ad67430c988d8ccc16cbe396ff965 489 Gene3D G3DSA:3.40.50.2000 5 477 1.2E-175 T 12-10-2018 AFE_2678 4c2ad67430c988d8ccc16cbe396ff965 489 Pfam PF08323 Starch synthase catalytic domain 4 239 8.0E-70 T 12-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 AFE_2678 4c2ad67430c988d8ccc16cbe396ff965 489 Pfam PF00534 Glycosyl transferases group 1 299 442 1.4E-13 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_2678 4c2ad67430c988d8ccc16cbe396ff965 489 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 3 479 9.2E-164 T 12-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 AFE_2678 4c2ad67430c988d8ccc16cbe396ff965 489 Gene3D G3DSA:3.40.50.2000 253 464 1.2E-175 T 12-10-2018 AFE_2678 4c2ad67430c988d8ccc16cbe396ff965 489 Hamap MF_00484 Glycogen synthase [glgA]. 2 480 42.758 T 12-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 AFE_2678 4c2ad67430c988d8ccc16cbe396ff965 489 SUPERFAMILY SSF53756 6 481 7.22E-120 T 12-10-2018 AFE_2388 256ac8e6814a360251b88f2af0dccaac 409 Gene3D G3DSA:3.50.50.60 7 337 9.6E-69 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2388 256ac8e6814a360251b88f2af0dccaac 409 Gene3D G3DSA:3.30.9.50 78 268 9.6E-69 T 12-10-2018 AFE_2388 256ac8e6814a360251b88f2af0dccaac 409 SUPERFAMILY SSF51905 7 377 3.02E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2388 256ac8e6814a360251b88f2af0dccaac 409 Pfam PF01494 FAD binding domain 152 339 1.9E-12 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFE_2388 256ac8e6814a360251b88f2af0dccaac 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 7.9E-10 T 12-10-2018 AFE_2388 256ac8e6814a360251b88f2af0dccaac 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 7.9E-10 T 12-10-2018 AFE_2388 256ac8e6814a360251b88f2af0dccaac 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 7.9E-10 T 12-10-2018 AFE_2388 256ac8e6814a360251b88f2af0dccaac 409 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 7.9E-10 T 12-10-2018 AFE_2388 256ac8e6814a360251b88f2af0dccaac 409 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 388 1.5E-86 T 12-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 AFE_2388 256ac8e6814a360251b88f2af0dccaac 409 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 293 306 - T 12-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 AFE_2032 3909a09abc8e02b3a0e0c796eb764f37 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 215 4.5E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2032 3909a09abc8e02b3a0e0c796eb764f37 220 Gene3D G3DSA:3.40.50.2300 1 122 7.4E-39 T 12-10-2018 AFE_2032 3909a09abc8e02b3a0e0c796eb764f37 220 Pfam PF00072 Response regulator receiver domain 3 112 8.4E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_2032 3909a09abc8e02b3a0e0c796eb764f37 220 SMART SM00862 144 216 5.3E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2032 3909a09abc8e02b3a0e0c796eb764f37 220 SUPERFAMILY SSF52172 1 173 2.13E-37 T 12-10-2018 IPR011006 CheY-like superfamily AFE_2032 3909a09abc8e02b3a0e0c796eb764f37 220 Gene3D G3DSA:1.10.10.10 125 219 1.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2032 3909a09abc8e02b3a0e0c796eb764f37 220 SMART SM00448 1 112 8.2E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0399 8bbce48ebff2565f2f188369a38dd564 158 Gene3D G3DSA:3.30.420.10 2 151 5.2E-50 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_0399 8bbce48ebff2565f2f188369a38dd564 158 Hamap MF_00042 Ribonuclease H [rnhA]. 3 151 30.666 T 12-10-2018 IPR022892 Ribonuclease HI GO:0004523 AFE_0399 8bbce48ebff2565f2f188369a38dd564 158 Pfam PF00075 RNase H 6 139 5.2E-40 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 AFE_0399 8bbce48ebff2565f2f188369a38dd564 158 SUPERFAMILY SSF53098 4 144 5.56E-49 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 Pfam PF00226 DnaJ domain 5 66 1.5E-24 T 12-10-2018 IPR001623 DnaJ domain AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 PRINTS PR00625 DnaJ domain signature 25 40 1.5E-23 T 12-10-2018 IPR001623 DnaJ domain AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 PRINTS PR00625 DnaJ domain signature 61 80 1.5E-23 T 12-10-2018 IPR001623 DnaJ domain AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 PRINTS PR00625 DnaJ domain signature 7 25 1.5E-23 T 12-10-2018 IPR001623 DnaJ domain AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 PRINTS PR00625 DnaJ domain signature 41 61 1.5E-23 T 12-10-2018 IPR001623 DnaJ domain AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 Gene3D G3DSA:2.60.260.20 207 308 1.2E-29 T 12-10-2018 AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 SMART SM00271 4 61 1.0E-26 T 12-10-2018 IPR001623 DnaJ domain AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 Pfam PF01556 DnaJ C terminal domain 130 286 2.0E-38 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 SUPERFAMILY SSF49493 211 297 1.57E-22 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 Gene3D G3DSA:2.60.260.20 123 206 1.3E-21 T 12-10-2018 AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 12-10-2018 IPR018253 DnaJ domain, conserved site AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 SUPERFAMILY SSF49493 122 220 1.44E-19 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 SUPERFAMILY SSF46565 2 117 1.57E-33 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFE_3102 060b9035d76ce3eefc3b88b0567f6120 310 Gene3D G3DSA:1.10.287.110 2 120 4.6E-35 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFE_2708 2cf11bd2bcb8d4e99cb38d79f5359eba 147 Gene3D G3DSA:1.20.120.1220 2 115 4.1E-5 T 12-10-2018 AFE_2708 2cf11bd2bcb8d4e99cb38d79f5359eba 147 Pfam PF01478 Type IV leader peptidase family 3 105 4.9E-10 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 AFE_1685 405fdd5b89a9243272d0a5f65b2a1228 98 SMART SM00877 7 84 5.4E-28 T 12-10-2018 IPR000249 Microcompartment protein, bacteria AFE_1685 405fdd5b89a9243272d0a5f65b2a1228 98 Gene3D G3DSA:3.30.70.1710 1 98 2.0E-34 T 12-10-2018 AFE_1685 405fdd5b89a9243272d0a5f65b2a1228 98 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 8 69 1.0E-19 T 12-10-2018 AFE_1685 405fdd5b89a9243272d0a5f65b2a1228 98 SUPERFAMILY SSF143414 8 94 4.84E-27 T 12-10-2018 IPR037233 CcmK-like superfamily AFE_1685 405fdd5b89a9243272d0a5f65b2a1228 98 Pfam PF00936 BMC domain 8 83 3.3E-24 T 12-10-2018 IPR000249 Microcompartment protein, bacteria AFE_1685 405fdd5b89a9243272d0a5f65b2a1228 98 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 25 44 - T 12-10-2018 IPR020808 Bacterial microcompartments protein, conserved site AFE_0166 6d53f062f029f3915ec59a986d10476f 184 Gene3D G3DSA:3.30.40.60 63 162 1.4E-24 T 12-10-2018 AFE_0166 6d53f062f029f3915ec59a986d10476f 184 Pfam PF14279 HNH endonuclease 90 144 4.3E-17 T 12-10-2018 IPR029471 HNH endonuclease 5 AFE_0166 6d53f062f029f3915ec59a986d10476f 184 SMART SM00507 77 130 7.5E-13 T 12-10-2018 IPR003615 HNH nuclease AFE_3198 94e2716ad464ba8b776490178cb15427 721 Pfam PF00665 Integrase core domain 279 419 1.4E-22 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFE_3198 94e2716ad464ba8b776490178cb15427 721 Gene3D G3DSA:3.30.420.10 273 482 1.1E-18 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_3198 94e2716ad464ba8b776490178cb15427 721 Pfam PF09299 Mu transposase, C-terminal 510 575 7.9E-7 T 12-10-2018 IPR015378 Transposase-like, Mu, C-terminal AFE_3198 94e2716ad464ba8b776490178cb15427 721 SUPERFAMILY SSF53098 280 467 5.69E-8 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_0901 3c1745b65529853894ece28ba7b24cbb 433 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFE_0901 3c1745b65529853894ece28ba7b24cbb 433 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 418 8.4E-118 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFE_0901 3c1745b65529853894ece28ba7b24cbb 433 ProSitePatterns PS00885 EPSP synthase signature 2. 339 357 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFE_0901 3c1745b65529853894ece28ba7b24cbb 433 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 423 4.3E-121 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFE_0901 3c1745b65529853894ece28ba7b24cbb 433 PIRSF PIRSF000505 1 429 1.7E-113 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFE_0901 3c1745b65529853894ece28ba7b24cbb 433 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 427 32.138 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFE_0901 3c1745b65529853894ece28ba7b24cbb 433 SUPERFAMILY SSF55205 4 425 5.23E-127 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFE_0901 3c1745b65529853894ece28ba7b24cbb 433 Gene3D G3DSA:3.65.10.10 14 417 1.6E-152 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFE_0901 3c1745b65529853894ece28ba7b24cbb 433 Gene3D G3DSA:3.65.10.10 22 229 1.6E-152 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFE_0161 7d77b3251df20fad3ad0cd0af4c0769c 212 Pfam PF05494 MlaC protein 33 196 2.9E-47 T 12-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC AFE_0161 7d77b3251df20fad3ad0cd0af4c0769c 212 PIRSF PIRSF004649 1 207 1.4E-47 T 12-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC AFE_0161 7d77b3251df20fad3ad0cd0af4c0769c 212 Gene3D G3DSA:3.10.450.710 25 200 9.0E-44 T 12-10-2018 AFE_1378 f790bdba624d6f7bfe70dde3ccf8a88d 694 Gene3D G3DSA:3.40.50.1390 14 171 4.8E-22 T 12-10-2018 AFE_1378 f790bdba624d6f7bfe70dde3ccf8a88d 694 Pfam PF00239 Resolvase, N terminal domain 18 169 1.7E-20 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFE_1378 f790bdba624d6f7bfe70dde3ccf8a88d 694 SMART SM00857 18 170 2.2E-24 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFE_1378 f790bdba624d6f7bfe70dde3ccf8a88d 694 Pfam PF13408 Recombinase zinc beta ribbon domain 332 388 2.1E-10 T 12-10-2018 IPR025827 Recombinase zinc beta ribbon domain AFE_1378 f790bdba624d6f7bfe70dde3ccf8a88d 694 Pfam PF07508 Recombinase 197 313 1.9E-11 T 12-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 AFE_1378 f790bdba624d6f7bfe70dde3ccf8a88d 694 SUPERFAMILY SSF53041 18 169 9.29E-20 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 Gene3D G3DSA:3.30.70.1440 649 845 3.2E-296 T 12-10-2018 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 Gene3D G3DSA:3.30.70.1320 135 326 3.2E-296 T 12-10-2018 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 SUPERFAMILY SSF82866 785 1009 2.22E-48 T 12-10-2018 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 SUPERFAMILY SSF82714 702 787 1.03E-11 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_3262 a819c826211768d98eca697cc1cdb504 1036 SUPERFAMILY SSF82693 551 651 4.97E-15 T 12-10-2018 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 SUPERFAMILY SSF82693 40 127 7.5E-22 T 12-10-2018 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 Gene3D G3DSA:3.30.70.1430 553 648 3.2E-296 T 12-10-2018 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 Gene3D G3DSA:3.30.70.1430 40 796 3.2E-296 T 12-10-2018 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 Gene3D G3DSA:3.30.2090.10 179 269 3.2E-296 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_3262 a819c826211768d98eca697cc1cdb504 1036 Gene3D G3DSA:3.30.2090.10 701 788 3.2E-296 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_3262 a819c826211768d98eca697cc1cdb504 1036 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.9E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 3.9E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 3.9E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 3.9E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 PRINTS PR00702 Acriflavin resistance protein family signature 538 555 3.9E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 3.9E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 3.9E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 PRINTS PR00702 Acriflavin resistance protein family signature 606 620 3.9E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.9E-74 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 SUPERFAMILY SSF82866 291 490 1.16E-42 T 12-10-2018 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 Pfam PF00873 AcrB/AcrD/AcrF family 3 1005 3.6E-295 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 Gene3D G3DSA:1.20.1640.10 10 498 3.2E-296 T 12-10-2018 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 SUPERFAMILY SSF82714 183 266 2.22E-15 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_3262 a819c826211768d98eca697cc1cdb504 1036 Gene3D G3DSA:1.20.1640.10 499 1002 3.2E-296 T 12-10-2018 AFE_3262 a819c826211768d98eca697cc1cdb504 1036 SUPERFAMILY SSF82693 137 322 7.32E-19 T 12-10-2018 AFE_2876 e5d0b303106d2e98a110eb0acc69addf 207 SUPERFAMILY SSF75169 43 201 7.8E-17 T 12-10-2018 IPR027396 DsrEFH-like AFE_2876 e5d0b303106d2e98a110eb0acc69addf 207 Gene3D G3DSA:3.40.1260.10 36 207 2.9E-36 T 12-10-2018 IPR027396 DsrEFH-like AFE_2876 e5d0b303106d2e98a110eb0acc69addf 207 Pfam PF13686 DsrE/DsrF/DrsH-like family 42 206 1.9E-45 T 12-10-2018 IPR032836 DsrE2-like family AFE_0049 6f5379b770a570bdbf8fed4b5a4a1740 337 Pfam PF13531 Bacterial extracellular solute-binding protein 84 331 1.9E-52 T 12-10-2018 AFE_0049 6f5379b770a570bdbf8fed4b5a4a1740 337 SUPERFAMILY SSF53850 83 332 6.46E-38 T 12-10-2018 AFE_0049 6f5379b770a570bdbf8fed4b5a4a1740 337 Gene3D G3DSA:3.40.190.10 86 330 6.8E-23 T 12-10-2018 AFE_0049 6f5379b770a570bdbf8fed4b5a4a1740 337 Gene3D G3DSA:3.40.190.10 174 293 6.8E-23 T 12-10-2018 AFE_0643 4cb222b0092023df979c1c5a9906ccf0 260 Gene3D G3DSA:3.20.20.70 1 259 6.7E-116 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_0643 4cb222b0092023df979c1c5a9906ccf0 260 SUPERFAMILY SSF110399 4 245 4.71E-87 T 12-10-2018 AFE_0643 4cb222b0092023df979c1c5a9906ccf0 260 Hamap MF_00443 Thiazole synthase [thiG]. 5 259 42.232 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFE_0643 4cb222b0092023df979c1c5a9906ccf0 260 Pfam PF05690 Thiazole biosynthesis protein ThiG 8 253 5.1E-109 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFE_1221 0232e391d7d452e657216f7107a5418e 204 Pfam PF01555 DNA methylase 125 184 2.1E-10 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 AFE_1221 0232e391d7d452e657216f7107a5418e 204 Gene3D G3DSA:3.40.50.150 54 200 2.0E-14 T 12-10-2018 AFE_1221 0232e391d7d452e657216f7107a5418e 204 SUPERFAMILY SSF53335 72 187 1.08E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 Gene3D G3DSA:3.30.420.40 5 379 1.5E-163 T 12-10-2018 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 Gene3D G3DSA:3.90.640.10 229 316 1.5E-163 T 12-10-2018 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 Gene3D G3DSA:1.20.1270.10 524 602 2.8E-16 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 SUPERFAMILY SSF100934 507 605 4.19E-14 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 631 36.099 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.0E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 PRINTS PR00301 70kDa heat shock protein signature 138 158 1.0E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 PRINTS PR00301 70kDa heat shock protein signature 365 385 1.0E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 PRINTS PR00301 70kDa heat shock protein signature 388 407 1.0E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 PRINTS PR00301 70kDa heat shock protein signature 334 350 1.0E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.0E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 PRINTS PR00301 70kDa heat shock protein signature 198 208 1.0E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 PRINTS PR00301 70kDa heat shock protein signature 469 485 1.0E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.0E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 SUPERFAMILY SSF53067 187 382 5.48E-64 T 12-10-2018 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 Pfam PF00012 Hsp70 protein 4 600 5.6E-256 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 600 1.8E-285 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 Gene3D G3DSA:2.60.34.10 383 523 2.9E-64 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 SUPERFAMILY SSF100920 385 540 5.49E-61 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 Gene3D G3DSA:3.30.420.40 180 366 1.5E-163 T 12-10-2018 AFE_2665 4895fbc4f3a029bd11dc06e963026fb4 634 SUPERFAMILY SSF53067 4 183 2.02E-68 T 12-10-2018 AFE_0749 8461d342bb8e24e695faf9e78e2aa09d 617 Gene3D G3DSA:3.20.20.60 421 582 8.0E-58 T 12-10-2018 AFE_0749 8461d342bb8e24e695faf9e78e2aa09d 617 Pfam PF00224 Pyruvate kinase, barrel domain 131 211 1.9E-9 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_0749 8461d342bb8e24e695faf9e78e2aa09d 617 Pfam PF00224 Pyruvate kinase, barrel domain 354 588 1.2E-33 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_0749 8461d342bb8e24e695faf9e78e2aa09d 617 Gene3D G3DSA:2.40.33.10 327 420 8.0E-58 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_0749 8461d342bb8e24e695faf9e78e2aa09d 617 Gene3D G3DSA:2.40.33.10 201 216 5.2E-18 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFE_0749 8461d342bb8e24e695faf9e78e2aa09d 617 SUPERFAMILY SSF50800 329 420 1.92E-6 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFE_0749 8461d342bb8e24e695faf9e78e2aa09d 617 SUPERFAMILY SSF51621 114 592 1.81E-61 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFE_0749 8461d342bb8e24e695faf9e78e2aa09d 617 Gene3D G3DSA:3.20.20.60 133 200 5.2E-18 T 12-10-2018 AFE_2883 d0033ff105bc3e9cc44aed3e4cb826b9 356 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 26 313 4.3E-45 T 12-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal AFE_2883 d0033ff105bc3e9cc44aed3e4cb826b9 356 SUPERFAMILY SSF56235 26 328 1.77E-95 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_2883 d0033ff105bc3e9cc44aed3e4cb826b9 356 Gene3D G3DSA:3.60.60.10 23 342 1.6E-122 T 12-10-2018 AFE_0453 6fe37e4e00a1e3bcb36a53ed2ca5c196 301 Gene3D G3DSA:2.30.30.100 252 297 1.0E-5 T 12-10-2018 AFE_0453 6fe37e4e00a1e3bcb36a53ed2ca5c196 301 SUPERFAMILY SSF55681 68 247 1.37E-38 T 12-10-2018 AFE_0453 6fe37e4e00a1e3bcb36a53ed2ca5c196 301 Gene3D G3DSA:3.30.930.10 63 249 1.1E-43 T 12-10-2018 AFE_0453 6fe37e4e00a1e3bcb36a53ed2ca5c196 301 Pfam PF03099 Biotin/lipoate A/B protein ligase family 90 191 7.9E-9 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFE_0453 6fe37e4e00a1e3bcb36a53ed2ca5c196 301 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 71 296 3.1E-40 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFE_2232 2f84cf9f1f4fbf30b6f0d87f337c3d04 583 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 577 33.19 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_2232 2f84cf9f1f4fbf30b6f0d87f337c3d04 583 PIRSF PIRSF001294 1 579 2.9E-218 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_2232 2f84cf9f1f4fbf30b6f0d87f337c3d04 583 Pfam PF03814 Potassium-transporting ATPase A subunit 10 575 1.1E-221 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_2232 2f84cf9f1f4fbf30b6f0d87f337c3d04 583 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 4 576 1.9E-206 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_0590 bf8577d81a515a070918cf5354059842 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 1.6E-30 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFE_0590 bf8577d81a515a070918cf5354059842 67 PRINTS PR00050 Cold shock protein signature 25 34 3.1E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFE_0590 bf8577d81a515a070918cf5354059842 67 PRINTS PR00050 Cold shock protein signature 4 19 3.1E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFE_0590 bf8577d81a515a070918cf5354059842 67 PRINTS PR00050 Cold shock protein signature 40 58 3.1E-18 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFE_0590 bf8577d81a515a070918cf5354059842 67 SUPERFAMILY SSF50249 1 65 1.41E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0590 bf8577d81a515a070918cf5354059842 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 12-10-2018 IPR019844 Cold-shock conserved site AFE_0590 bf8577d81a515a070918cf5354059842 67 SMART SM00357 3 67 1.3E-29 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 AFE_0590 bf8577d81a515a070918cf5354059842 67 PIRSF PIRSF002599 1 67 2.7E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 AFE_0590 bf8577d81a515a070918cf5354059842 67 Gene3D G3DSA:2.40.50.140 1 66 6.2E-31 T 12-10-2018 AFE_1365 4a0dfcfda9b65e037b0dd7dd62945fb7 471 Gene3D G3DSA:3.30.40.60 166 303 2.4E-20 T 12-10-2018 AFE_1365 4a0dfcfda9b65e037b0dd7dd62945fb7 471 SMART SM00507 196 247 3.5E-13 T 12-10-2018 IPR003615 HNH nuclease AFE_1365 4a0dfcfda9b65e037b0dd7dd62945fb7 471 Pfam PF14279 HNH endonuclease 209 260 9.4E-13 T 12-10-2018 IPR029471 HNH endonuclease 5 AFE_1365 4a0dfcfda9b65e037b0dd7dd62945fb7 471 Pfam PF14239 RRXRR protein 3 190 1.2E-66 T 12-10-2018 IPR025938 RRXRR domain AFE_0197 f8250550e4d9a275a52c9b4ec298d802 153 SUPERFAMILY SSF52304 7 150 9.16E-59 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFE_0197 f8250550e4d9a275a52c9b4ec298d802 153 Pfam PF01220 Dehydroquinase class II 8 144 4.4E-56 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFE_0197 f8250550e4d9a275a52c9b4ec298d802 153 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 9 144 7.0E-48 T 12-10-2018 AFE_0197 f8250550e4d9a275a52c9b4ec298d802 153 ProSitePatterns PS01029 Dehydroquinase class II signature. 11 28 - T 12-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFE_0197 f8250550e4d9a275a52c9b4ec298d802 153 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 153 66.046 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFE_0197 f8250550e4d9a275a52c9b4ec298d802 153 Gene3D G3DSA:3.40.50.9100 2 152 3.0E-59 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFE_0197 f8250550e4d9a275a52c9b4ec298d802 153 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 7 146 3.1E-56 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFE_0197 f8250550e4d9a275a52c9b4ec298d802 153 PIRSF PIRSF001399 4 151 1.2E-55 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFE_0394 8de7e2c0400b9a4b8a67dadffffde29d 89 Pfam PF00312 Ribosomal protein S15 8 88 3.9E-36 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0394 8de7e2c0400b9a4b8a67dadffffde29d 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0394 8de7e2c0400b9a4b8a67dadffffde29d 89 SMART SM01387 8 88 1.3E-51 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0394 8de7e2c0400b9a4b8a67dadffffde29d 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 3.0E-27 T 12-10-2018 AFE_0394 8de7e2c0400b9a4b8a67dadffffde29d 89 Gene3D G3DSA:1.10.287.10 2 89 1.1E-33 T 12-10-2018 AFE_0394 8de7e2c0400b9a4b8a67dadffffde29d 89 SUPERFAMILY SSF47060 3 89 1.68E-34 T 12-10-2018 IPR009068 S15/NS1, RNA-binding AFE_0394 8de7e2c0400b9a4b8a67dadffffde29d 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 4.3E-38 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0394 8de7e2c0400b9a4b8a67dadffffde29d 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.669 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1980 9dd5d7091f6ec61aa0190241e3f3ea4b 446 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 12 441 1.1E-135 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 AFE_1980 9dd5d7091f6ec61aa0190241e3f3ea4b 446 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 8 442 27.127 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 AFE_1980 9dd5d7091f6ec61aa0190241e3f3ea4b 446 Pfam PF02601 Exonuclease VII, large subunit 127 438 9.1E-95 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 AFE_1980 9dd5d7091f6ec61aa0190241e3f3ea4b 446 Pfam PF13742 OB-fold nucleic acid binding domain 11 103 8.4E-27 T 12-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 AFE_2543 09f670df0c6c679867f9f1530dbe206e 378 SMART SM00729 58 279 8.2E-18 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFE_2543 09f670df0c6c679867f9f1530dbe206e 378 Gene3D G3DSA:3.20.20.70 48 298 1.3E-17 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2543 09f670df0c6c679867f9f1530dbe206e 378 Pfam PF04055 Radical SAM superfamily 65 239 1.4E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_2543 09f670df0c6c679867f9f1530dbe206e 378 SUPERFAMILY SSF102114 58 279 1.31E-24 T 12-10-2018 AFE_1376 4af830a1da0111e86084def1e130637f 150 SUPERFAMILY SSF46689 43 146 5.38E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_1376 4af830a1da0111e86084def1e130637f 150 Pfam PF13518 Helix-turn-helix domain 44 95 3.3E-8 T 12-10-2018 AFE_2960 cf2176661ec65e43ad72fe70a75b4d4e 490 SUPERFAMILY SSF51182 191 476 8.35E-74 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_2960 cf2176661ec65e43ad72fe70a75b4d4e 490 Pfam PF00483 Nucleotidyl transferase 5 291 5.3E-54 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFE_2960 cf2176661ec65e43ad72fe70a75b4d4e 490 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 475 5.4E-172 T 12-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AFE_2960 cf2176661ec65e43ad72fe70a75b4d4e 490 Pfam PF01050 Mannose-6-phosphate isomerase 321 471 1.4E-67 T 12-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AFE_2960 cf2176661ec65e43ad72fe70a75b4d4e 490 SUPERFAMILY SSF53448 2 284 1.64E-66 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2960 cf2176661ec65e43ad72fe70a75b4d4e 490 Gene3D G3DSA:3.90.550.10 1 357 1.1E-113 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2960 cf2176661ec65e43ad72fe70a75b4d4e 490 Gene3D G3DSA:2.60.120.10 365 467 3.1E-17 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_2699 c5703142b5eccfdc6b7aca2e04f45031 279 Pfam PF13432 Tetratricopeptide repeat 124 185 2.2E-7 T 12-10-2018 AFE_2699 c5703142b5eccfdc6b7aca2e04f45031 279 Pfam PF13432 Tetratricopeptide repeat 69 113 0.0095 T 12-10-2018 AFE_2699 c5703142b5eccfdc6b7aca2e04f45031 279 Gene3D G3DSA:1.25.40.10 39 210 1.1E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2699 c5703142b5eccfdc6b7aca2e04f45031 279 SUPERFAMILY SSF48452 63 207 3.25E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0837 4a66ddbfed381aaa2075492bd0b90fcb 279 Gene3D G3DSA:3.40.50.300 30 188 4.3E-9 T 12-10-2018 AFE_0837 4a66ddbfed381aaa2075492bd0b90fcb 279 SUPERFAMILY SSF52540 43 263 2.94E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0837 4a66ddbfed381aaa2075492bd0b90fcb 279 Pfam PF13401 AAA domain 45 175 7.2E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0837 4a66ddbfed381aaa2075492bd0b90fcb 279 SMART SM00382 45 198 2.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0593 b6c234493eb91f860de45a59e9fe147f 170 SUPERFAMILY SSF64288 10 164 1.15E-27 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFE_0593 b6c234493eb91f860de45a59e9fe147f 170 Gene3D G3DSA:3.40.1410.10 4 164 1.2E-30 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFE_0593 b6c234493eb91f860de45a59e9fe147f 170 Pfam PF04345 Chorismate lyase 8 160 1.0E-16 T 12-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 Gene3D G3DSA:1.20.1640.10 505 1010 1.4E-282 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 Gene3D G3DSA:3.30.70.1430 40 803 1.4E-282 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 Gene3D G3DSA:3.30.70.1430 559 656 1.4E-282 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 SUPERFAMILY SSF82714 708 793 1.57E-16 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 SUPERFAMILY SSF82693 234 328 1.1E-15 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 SUPERFAMILY SSF82693 138 210 1.2E-6 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 SUPERFAMILY SSF82866 295 494 1.7E-48 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 Gene3D G3DSA:3.30.70.1440 657 852 1.4E-282 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 Gene3D G3DSA:3.30.70.1320 134 330 1.4E-282 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 PRINTS PR00702 Acriflavin resistance protein family signature 544 561 2.6E-70 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 2.6E-70 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 2.6E-70 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 2.6E-70 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 2.6E-70 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 2.6E-70 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.6E-70 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.6E-70 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 PRINTS PR00702 Acriflavin resistance protein family signature 612 626 2.6E-70 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 Pfam PF00873 AcrB/AcrD/AcrF family 4 1013 6.8E-259 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 Gene3D G3DSA:1.20.1640.10 10 504 1.4E-282 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 Gene3D G3DSA:3.30.2090.10 707 795 1.4E-282 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 SUPERFAMILY SSF82866 793 1015 2.09E-41 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 SUPERFAMILY SSF82693 557 659 1.94E-16 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 SUPERFAMILY SSF82693 40 130 3.92E-24 T 12-10-2018 AFE_1878 957f4edd7980d47ce65d3ff5bb03de00 1026 Gene3D G3DSA:3.30.2090.10 182 273 1.4E-282 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFE_0487 a094cc28597335aeb0c1c5614863ed4e 193 Pfam PF04028 Domain of unknown function (DUF374) 32 96 1.2E-25 T 12-10-2018 IPR007172 Domain of unknown function DUF374 AFE_0487 a094cc28597335aeb0c1c5614863ed4e 193 ProDom PD032436 LIPOPROTEIN UNCHARACTERIZED PROBABLE CJ0457C SIMILAR TRANSFERASE BACTERIA PRECURSOR SIGNAL CC0304 5 95 3.0E-15 T 12-10-2018 IPR007172 Domain of unknown function DUF374 AFE_2628 46e122a85e72e47b181d3a4e2c426e04 202 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 147 7.0E-22 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2628 46e122a85e72e47b181d3a4e2c426e04 202 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 33 159 2.0E-44 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2628 46e122a85e72e47b181d3a4e2c426e04 202 Gene3D G3DSA:3.30.460.80 1 139 1.2E-44 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2628 46e122a85e72e47b181d3a4e2c426e04 202 SUPERFAMILY SSF143243 8 180 2.75E-55 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2628 46e122a85e72e47b181d3a4e2c426e04 202 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 120 141 - T 12-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2628 46e122a85e72e47b181d3a4e2c426e04 202 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 16 167 35.086 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2628 46e122a85e72e47b181d3a4e2c426e04 202 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 31 157 2.4E-42 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2107 8b840e81570ebcd84d58885c62806a5b 238 Pfam PF13346 ABC-2 family transporter protein 7 190 3.0E-6 T 12-10-2018 IPR025699 ABC-2 membrane transporter-like AFE_2268 0a1a0a912b59f1c4b1208aeeb5550466 237 PRINTS PR01217 Proline rich extensin signature 6 18 2.9E-11 T 12-10-2018 AFE_2268 0a1a0a912b59f1c4b1208aeeb5550466 237 PRINTS PR01217 Proline rich extensin signature 89 105 2.9E-11 T 12-10-2018 AFE_2268 0a1a0a912b59f1c4b1208aeeb5550466 237 PRINTS PR01217 Proline rich extensin signature 65 86 2.9E-11 T 12-10-2018 AFE_2268 0a1a0a912b59f1c4b1208aeeb5550466 237 PRINTS PR01217 Proline rich extensin signature 41 53 2.9E-11 T 12-10-2018 AFE_2268 0a1a0a912b59f1c4b1208aeeb5550466 237 PRINTS PR01217 Proline rich extensin signature 119 136 2.9E-11 T 12-10-2018 AFE_2268 0a1a0a912b59f1c4b1208aeeb5550466 237 Gene3D G3DSA:3.30.1150.10 115 233 3.2E-17 T 12-10-2018 AFE_2268 0a1a0a912b59f1c4b1208aeeb5550466 237 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 159 231 1.6E-11 T 12-10-2018 IPR006260 TonB/TolA, C-terminal AFE_2268 0a1a0a912b59f1c4b1208aeeb5550466 237 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 161 229 7.8E-10 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 AFE_2268 0a1a0a912b59f1c4b1208aeeb5550466 237 SUPERFAMILY SSF74653 141 224 3.66E-13 T 12-10-2018 AFE_1115 65a583d5ddf410a15b5674d210e6998f 294 SUPERFAMILY SSF56300 3 237 1.22E-34 T 12-10-2018 AFE_1115 65a583d5ddf410a15b5674d210e6998f 294 Gene3D G3DSA:3.60.21.10 9 266 5.7E-37 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFE_1115 65a583d5ddf410a15b5674d210e6998f 294 Pfam PF00149 Calcineurin-like phosphoesterase 22 153 5.0E-9 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFE_2209 b1963ee305ed9b2108d1d0278753fdf2 204 SUPERFAMILY SSF48498 85 198 1.17E-21 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFE_2209 b1963ee305ed9b2108d1d0278753fdf2 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 6.6E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFE_2209 b1963ee305ed9b2108d1d0278753fdf2 204 Pfam PF16925 Bacterial transcriptional repressor C-terminal 87 185 3.7E-12 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal AFE_2209 b1963ee305ed9b2108d1d0278753fdf2 204 SUPERFAMILY SSF46689 5 79 5.64E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_2209 b1963ee305ed9b2108d1d0278753fdf2 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 4.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFE_2209 b1963ee305ed9b2108d1d0278753fdf2 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 4.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFE_2209 b1963ee305ed9b2108d1d0278753fdf2 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFE_2209 b1963ee305ed9b2108d1d0278753fdf2 204 Gene3D G3DSA:1.10.357.10 3 204 1.4E-46 T 12-10-2018 AFE_1952 0ea7581ad41b0aa786154ff4851f000a 223 Pfam PF09968 Uncharacterized protein domain (DUF2202) 57 217 2.0E-57 T 12-10-2018 IPR019243 Domain of unknown function DUF2202 AFE_1952 0ea7581ad41b0aa786154ff4851f000a 223 SUPERFAMILY SSF47240 58 196 2.03E-8 T 12-10-2018 IPR009078 Ferritin-like superfamily AFE_1952 0ea7581ad41b0aa786154ff4851f000a 223 Gene3D G3DSA:1.20.1260.10 52 223 2.1E-57 T 12-10-2018 IPR012347 Ferritin-like AFE_0546 bfd96d4eadfc065bc50af5286a7eed97 70 Gene3D G3DSA:2.60.260.40 6 60 1.4E-12 T 12-10-2018 AFE_0546 bfd96d4eadfc065bc50af5286a7eed97 70 Pfam PF10276 Zinc-finger domain 32 57 4.0E-10 T 12-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_3050 bd5c7ca5e396e037261d8ba537d52d9c 268 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 240 16.766 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFE_3050 bd5c7ca5e396e037261d8ba537d52d9c 268 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 10 226 4.7E-66 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFE_3050 bd5c7ca5e396e037261d8ba537d52d9c 268 Pfam PF00902 Sec-independent protein translocase protein (TatC) 12 221 5.0E-66 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFE_3050 bd5c7ca5e396e037261d8ba537d52d9c 268 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 2.2E-43 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFE_3050 bd5c7ca5e396e037261d8ba537d52d9c 268 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 85 103 2.2E-43 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFE_3050 bd5c7ca5e396e037261d8ba537d52d9c 268 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 8 35 2.2E-43 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFE_3050 bd5c7ca5e396e037261d8ba537d52d9c 268 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 129 2.2E-43 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFE_1371 562f79438630a1a720ff9f94ea2b379e 1381 SMART SM00487 915 1098 3.4E-24 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_1371 562f79438630a1a720ff9f94ea2b379e 1381 Gene3D G3DSA:3.40.50.10810 891 1125 1.3E-61 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily AFE_1371 562f79438630a1a720ff9f94ea2b379e 1381 Pfam PF00271 Helicase conserved C-terminal domain 1208 1319 1.1E-18 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_1371 562f79438630a1a720ff9f94ea2b379e 1381 SUPERFAMILY SSF52540 1127 1375 2.03E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1371 562f79438630a1a720ff9f94ea2b379e 1381 SMART SM00490 1237 1319 2.2E-22 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_1371 562f79438630a1a720ff9f94ea2b379e 1381 Pfam PF00176 SNF2 family N-terminal domain 937 1198 1.7E-48 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 AFE_1371 562f79438630a1a720ff9f94ea2b379e 1381 SUPERFAMILY SSF52540 908 1126 2.95E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1371 562f79438630a1a720ff9f94ea2b379e 1381 Gene3D G3DSA:1.20.120.850 1148 1368 3.7E-68 T 12-10-2018 AFE_1371 562f79438630a1a720ff9f94ea2b379e 1381 Gene3D G3DSA:3.40.50.300 1133 1333 3.7E-68 T 12-10-2018 AFE_1771 1974bca8480ebe796074b53b6261131f 261 Pfam PF02548 Ketopantoate hydroxymethyltransferase 5 256 1.0E-95 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFE_1771 1974bca8480ebe796074b53b6261131f 261 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 3 261 35.714 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFE_1771 1974bca8480ebe796074b53b6261131f 261 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 6 259 7.4E-87 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFE_1771 1974bca8480ebe796074b53b6261131f 261 PIRSF PIRSF000388 1 261 1.0E-93 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFE_1771 1974bca8480ebe796074b53b6261131f 261 SUPERFAMILY SSF51621 5 258 6.28E-89 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFE_1771 1974bca8480ebe796074b53b6261131f 261 Gene3D G3DSA:3.20.20.60 3 261 8.3E-94 T 12-10-2018 AFE_1492 ea5fc17f3b0979a14f6ba5457e094a33 711 Pfam PF00593 TonB dependent receptor 263 703 1.2E-33 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_1492 ea5fc17f3b0979a14f6ba5457e094a33 711 Gene3D G3DSA:2.170.130.10 55 176 4.1E-12 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_1492 ea5fc17f3b0979a14f6ba5457e094a33 711 Gene3D G3DSA:2.40.170.20 200 711 8.5E-57 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily AFE_1492 ea5fc17f3b0979a14f6ba5457e094a33 711 SUPERFAMILY SSF56935 62 711 9.89E-74 T 12-10-2018 AFE_1492 ea5fc17f3b0979a14f6ba5457e094a33 711 Pfam PF07715 TonB-dependent Receptor Plug Domain 65 172 4.5E-13 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain AFE_2347 a2eae2120f0762f26a262da888c8b7f6 103 TIGRFAM TIGR04535 ferrit_encaps: ferritin-like protein 6 98 8.3E-40 T 12-10-2018 IPR030907 Ferritin-like protein AFE_2347 a2eae2120f0762f26a262da888c8b7f6 103 SUPERFAMILY SSF47240 7 93 8.12E-24 T 12-10-2018 IPR009078 Ferritin-like superfamily AFE_2110 516dcd1c001319f405ac4c44cce66dcb 478 Gene3D G3DSA:1.10.10.410 415 478 6.4E-25 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AFE_2110 516dcd1c001319f405ac4c44cce66dcb 478 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 3 475 2.7E-176 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AFE_2110 516dcd1c001319f405ac4c44cce66dcb 478 SUPERFAMILY SSF55931 6 297 1.05E-119 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFE_2110 516dcd1c001319f405ac4c44cce66dcb 478 Pfam PF02637 GatB domain 329 475 1.6E-49 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFE_2110 516dcd1c001319f405ac4c44cce66dcb 478 Gene3D G3DSA:1.10.150.380 298 414 5.0E-34 T 12-10-2018 AFE_2110 516dcd1c001319f405ac4c44cce66dcb 478 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 146 160 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 AFE_2110 516dcd1c001319f405ac4c44cce66dcb 478 SUPERFAMILY SSF89095 298 401 5.49E-31 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 AFE_2110 516dcd1c001319f405ac4c44cce66dcb 478 Pfam PF02934 GatB/GatE catalytic domain 7 290 5.3E-112 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 AFE_2110 516dcd1c001319f405ac4c44cce66dcb 478 SMART SM00845 329 475 1.6E-74 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFE_2110 516dcd1c001319f405ac4c44cce66dcb 478 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 4 476 38.479 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 701 719 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 Gene3D G3DSA:3.30.1490.20 1 194 4.8E-67 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 Gene3D G3DSA:3.30.470.20 195 362 4.2E-54 T 12-10-2018 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 SUPERFAMILY SSF51621 468 798 1.91E-94 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 SUPERFAMILY SSF56059 3 389 1.53E-103 T 12-10-2018 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 Gene3D G3DSA:3.20.20.60 484 795 8.2E-96 T 12-10-2018 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 PIRSF PIRSF000854 1 801 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 Gene3D G3DSA:3.50.30.10 363 471 2.2E-38 T 12-10-2018 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 420 431 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 349 1.6E-112 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 6 797 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 SUPERFAMILY SSF52009 355 473 5.76E-32 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 Pfam PF00391 PEP-utilising enzyme, mobile domain 390 461 6.0E-25 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFE_1816 1356450f9e8f77f881ebb44a274a0e68 803 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 480 793 6.1E-58 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AFE_0323 68a27798b477be9f8ef7d644d008d7a2 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.025 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 AFE_0323 68a27798b477be9f8ef7d644d008d7a2 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 3.6E-67 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 AFE_0323 68a27798b477be9f8ef7d644d008d7a2 156 Gene3D G3DSA:1.10.455.10 2 156 4.4E-63 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily AFE_0323 68a27798b477be9f8ef7d644d008d7a2 156 SUPERFAMILY SSF47973 2 149 5.23E-60 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily AFE_0323 68a27798b477be9f8ef7d644d008d7a2 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0323 68a27798b477be9f8ef7d644d008d7a2 156 PIRSF PIRSF002122 4 156 1.2E-61 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 AFE_0323 68a27798b477be9f8ef7d644d008d7a2 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 3.2E-65 T 12-10-2018 IPR023798 Ribosomal protein S7 domain AFE_0662 e8628cd27f0d4bb44a814c3952e351df 613 Pfam PF00920 Dehydratase family 86 609 6.3E-215 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_0662 e8628cd27f0d4bb44a814c3952e351df 613 SUPERFAMILY SSF52016 432 611 1.41E-60 T 12-10-2018 AFE_0662 e8628cd27f0d4bb44a814c3952e351df 613 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 174 184 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_0662 e8628cd27f0d4bb44a814c3952e351df 613 SUPERFAMILY SSF143975 49 431 6.54E-126 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_0662 e8628cd27f0d4bb44a814c3952e351df 613 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 56 612 44.989 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_0662 e8628cd27f0d4bb44a814c3952e351df 613 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 520 531 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_0662 e8628cd27f0d4bb44a814c3952e351df 613 Gene3D G3DSA:3.50.30.80 432 583 2.4E-54 T 12-10-2018 AFE_0662 e8628cd27f0d4bb44a814c3952e351df 613 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 69 612 7.0E-231 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_1691 f5f3147c64f850d9f71de9bc0e0a0645 473 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 147 455 6.0E-129 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1691 f5f3147c64f850d9f71de9bc0e0a0645 473 Hamap MF_01338 Ribulose bisphosphate carboxylase large chain [rbcL]. 2 468 60.271 T 12-10-2018 IPR020888 Ribulose bisphosphate carboxylase large subunit, type I GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1691 f5f3147c64f850d9f71de9bc0e0a0645 473 SUPERFAMILY SSF54966 4 141 2.88E-57 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1691 f5f3147c64f850d9f71de9bc0e0a0645 473 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 189 197 - T 12-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1691 f5f3147c64f850d9f71de9bc0e0a0645 473 Gene3D G3DSA:3.20.20.110 143 473 6.5E-152 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1691 f5f3147c64f850d9f71de9bc0e0a0645 473 Gene3D G3DSA:3.30.70.150 15 141 1.2E-49 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1691 f5f3147c64f850d9f71de9bc0e0a0645 473 SUPERFAMILY SSF51649 142 466 1.57E-142 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1691 f5f3147c64f850d9f71de9bc0e0a0645 473 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 17 137 5.2E-44 T 12-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_1677 792e4963f173f3b8c44aa3d215166ccd 783 Gene3D G3DSA:3.40.50.410 587 768 1.6E-16 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_1677 792e4963f173f3b8c44aa3d215166ccd 783 Pfam PF00092 von Willebrand factor type A domain 594 751 2.0E-7 T 12-10-2018 IPR002035 von Willebrand factor, type A AFE_1677 792e4963f173f3b8c44aa3d215166ccd 783 SMART SM00327 591 775 9.9E-16 T 12-10-2018 IPR002035 von Willebrand factor, type A AFE_1677 792e4963f173f3b8c44aa3d215166ccd 783 SUPERFAMILY SSF53300 592 774 9.94E-21 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_0699 35e9b8c6e6bafae5b2404f44126064a9 320 Gene3D G3DSA:3.40.190.10 93 303 5.6E-96 T 12-10-2018 AFE_0699 35e9b8c6e6bafae5b2404f44126064a9 320 SUPERFAMILY SSF53850 89 299 4.27E-43 T 12-10-2018 AFE_0699 35e9b8c6e6bafae5b2404f44126064a9 320 Gene3D G3DSA:3.40.190.10 167 267 5.6E-96 T 12-10-2018 AFE_0699 35e9b8c6e6bafae5b2404f44126064a9 320 SUPERFAMILY SSF46785 1 88 2.72E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0699 35e9b8c6e6bafae5b2404f44126064a9 320 Pfam PF03466 LysR substrate binding domain 88 291 3.7E-44 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_0699 35e9b8c6e6bafae5b2404f44126064a9 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 4.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0699 35e9b8c6e6bafae5b2404f44126064a9 320 Gene3D G3DSA:1.10.10.10 1 86 8.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0699 35e9b8c6e6bafae5b2404f44126064a9 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.5E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0699 35e9b8c6e6bafae5b2404f44126064a9 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.5E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0699 35e9b8c6e6bafae5b2404f44126064a9 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.5E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0414 fe3688817b4aea895de6b3375b453772 81 Gene3D G3DSA:3.40.1620.10 1 41 5.2E-12 T 12-10-2018 AFE_0414 fe3688817b4aea895de6b3375b453772 81 SUPERFAMILY SSF143120 1 45 6.15E-9 T 12-10-2018 IPR036165 YefM-like superfamily AFE_0414 fe3688817b4aea895de6b3375b453772 81 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 44 1.0E-9 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM AFE_1637 2a3caa7076f20366214acc29af393d57 125 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 8 84 7.4E-9 T 12-10-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB AFE_1637 2a3caa7076f20366214acc29af393d57 125 ProDom PD012561 TRBD PLASMID CONJUGAL TRANSFER PRECURSOR SIGNAL MATING FORMATION PROBABLE PAIR 11 91 0.005 T 12-10-2018 AFE_1683 e9441e52c9fe1e94583c255de3d5d9d4 112 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 8 69 1.0E-19 T 12-10-2018 AFE_1683 e9441e52c9fe1e94583c255de3d5d9d4 112 SUPERFAMILY SSF143414 8 96 2.09E-27 T 12-10-2018 IPR037233 CcmK-like superfamily AFE_1683 e9441e52c9fe1e94583c255de3d5d9d4 112 SMART SM00877 7 84 1.3E-28 T 12-10-2018 IPR000249 Microcompartment protein, bacteria AFE_1683 e9441e52c9fe1e94583c255de3d5d9d4 112 Pfam PF00936 BMC domain 8 83 2.4E-24 T 12-10-2018 IPR000249 Microcompartment protein, bacteria AFE_1683 e9441e52c9fe1e94583c255de3d5d9d4 112 Gene3D G3DSA:3.30.70.1710 2 106 3.7E-35 T 12-10-2018 AFE_1683 e9441e52c9fe1e94583c255de3d5d9d4 112 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 25 44 - T 12-10-2018 IPR020808 Bacterial microcompartments protein, conserved site AFE_0089 f7848bce4e19610c5b7bf8de7715ed07 105 SUPERFAMILY SSF47413 15 98 1.16E-23 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_0089 f7848bce4e19610c5b7bf8de7715ed07 105 Pfam PF01381 Helix-turn-helix 21 69 2.6E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_0089 f7848bce4e19610c5b7bf8de7715ed07 105 Gene3D G3DSA:1.10.260.40 7 105 1.4E-29 T 12-10-2018 AFE_0089 f7848bce4e19610c5b7bf8de7715ed07 105 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 11 89 2.1E-32 T 12-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 AFE_2324 48d145510f20e89a2dce16801948736d 543 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 184 286 6.5E-11 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2324 48d145510f20e89a2dce16801948736d 543 SUPERFAMILY SSF55957 409 543 1.86E-42 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2324 48d145510f20e89a2dce16801948736d 543 SUPERFAMILY SSF53738 5 212 2.94E-45 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2324 48d145510f20e89a2dce16801948736d 543 SUPERFAMILY SSF53738 278 414 1.06E-37 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2324 48d145510f20e89a2dce16801948736d 543 Gene3D G3DSA:3.40.120.10 291 388 2.1E-38 T 12-10-2018 AFE_2324 48d145510f20e89a2dce16801948736d 543 Gene3D G3DSA:3.40.120.10 189 290 7.9E-37 T 12-10-2018 AFE_2324 48d145510f20e89a2dce16801948736d 543 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 205 224 1.7E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2324 48d145510f20e89a2dce16801948736d 543 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 106 120 1.7E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2324 48d145510f20e89a2dce16801948736d 543 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 241 254 1.7E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2324 48d145510f20e89a2dce16801948736d 543 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 270 285 1.7E-21 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2324 48d145510f20e89a2dce16801948736d 543 Gene3D G3DSA:3.30.310.50 389 543 8.6E-52 T 12-10-2018 AFE_2324 48d145510f20e89a2dce16801948736d 543 Gene3D G3DSA:3.40.120.10 2 188 9.1E-75 T 12-10-2018 AFE_2324 48d145510f20e89a2dce16801948736d 543 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 14 150 8.4E-32 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_2324 48d145510f20e89a2dce16801948736d 543 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 294 407 3.9E-31 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFE_0209 e3b7b6b114351c0db68332d0176cfeb7 360 Pfam PF00953 Glycosyl transferase family 4 99 283 1.5E-36 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 AFE_0209 e3b7b6b114351c0db68332d0176cfeb7 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_0209 e3b7b6b114351c0db68332d0176cfeb7 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 360 1.0E-131 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_0209 e3b7b6b114351c0db68332d0176cfeb7 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 6.6E-5 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_0209 e3b7b6b114351c0db68332d0176cfeb7 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 24.8 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_0209 e3b7b6b114351c0db68332d0176cfeb7 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 Gene3D G3DSA:3.30.980.10 69 221 2.0E-66 T 12-10-2018 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 Pfam PF03129 Anticodon binding domain 542 631 7.4E-22 T 12-10-2018 IPR004154 Anticodon-binding AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 635 34.622 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 SMART SM00863 169 218 1.7E-25 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 Gene3D G3DSA:3.30.930.10 222 532 8.2E-123 T 12-10-2018 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 SUPERFAMILY SSF81271 4 61 7.85E-12 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 630 2.7E-222 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 Pfam PF02824 TGS domain 4 61 1.3E-5 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 Gene3D G3DSA:3.30.54.20 130 186 2.0E-66 T 12-10-2018 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 SUPERFAMILY SSF52954 531 633 4.53E-31 T 12-10-2018 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 218 8.2E-16 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 530 5.5E-40 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 Gene3D G3DSA:3.40.50.800 533 642 4.8E-32 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 363 386 7.5E-55 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 330 358 7.5E-55 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 465 493 7.5E-55 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 508 521 7.5E-55 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 PRINTS PR01047 Threonyl-tRNA synthetase signature 535 547 7.5E-55 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 Gene3D G3DSA:3.10.20.30 3 62 7.5E-18 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 SUPERFAMILY SSF55681 242 527 5.63E-94 T 12-10-2018 AFE_2614 97f9d673bd1f76c4a8cddf3a05238a03 644 SUPERFAMILY SSF55186 63 240 2.88E-67 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 AFE_0799 8edc57b4635b718f2b355454a80617e4 186 Gene3D G3DSA:2.50.20.10 24 184 1.2E-15 T 12-10-2018 AFE_0799 8edc57b4635b718f2b355454a80617e4 186 SUPERFAMILY SSF89392 25 182 3.06E-13 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFE_2720 6538bd4b9b08320d8d02fde544722de4 233 Pfam PF13353 4Fe-4S single cluster domain 23 108 8.1E-8 T 12-10-2018 AFE_2720 6538bd4b9b08320d8d02fde544722de4 233 Gene3D G3DSA:3.20.20.70 11 225 3.5E-37 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2720 6538bd4b9b08320d8d02fde544722de4 233 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 12 198 4.9E-55 T 12-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein AFE_2720 6538bd4b9b08320d8d02fde544722de4 233 SUPERFAMILY SSF102114 22 204 1.44E-24 T 12-10-2018 AFE_2720 6538bd4b9b08320d8d02fde544722de4 233 Pfam PF04055 Radical SAM superfamily 31 174 6.6E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_0759 74680470bdb5d6aec59df0f4f1abfd74 216 Gene3D G3DSA:3.40.50.150 9 183 6.3E-37 T 12-10-2018 AFE_0759 74680470bdb5d6aec59df0f4f1abfd74 216 Pfam PF08241 Methyltransferase domain 42 127 1.9E-21 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFE_0759 74680470bdb5d6aec59df0f4f1abfd74 216 SUPERFAMILY SSF53335 6 180 1.2E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 14 440 68.968 T 12-10-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 SUPERFAMILY SSF53335 72 440 1.59E-75 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 Pfam PF01938 TRAM domain 15 61 8.4E-6 T 12-10-2018 IPR002792 TRAM domain AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 423 433 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 Gene3D G3DSA:3.40.1350.30 131 272 3.0E-99 T 12-10-2018 AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 Gene3D G3DSA:2.40.50.140 2 83 1.6E-25 T 12-10-2018 AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 433 2.0E-90 T 12-10-2018 AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 SUPERFAMILY SSF50249 7 63 1.66E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 372 401 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 260 439 1.7E-21 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 AFE_2828 11cbe7e204cf48b03faca0dec60fcea8 440 Gene3D G3DSA:3.40.50.150 84 435 3.0E-99 T 12-10-2018 AFE_2256 8b345aaa6580e5c65948b71e08e68323 263 SUPERFAMILY SSF56281 24 243 2.52E-25 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_2256 8b345aaa6580e5c65948b71e08e68323 263 Gene3D G3DSA:3.60.15.10 9 242 2.0E-28 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_2256 8b345aaa6580e5c65948b71e08e68323 263 SMART SM00849 26 184 2.1E-7 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_2256 8b345aaa6580e5c65948b71e08e68323 263 Pfam PF00753 Metallo-beta-lactamase superfamily 25 223 6.8E-18 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 6.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 6.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 6.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 6.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 6.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 251 4.2E-69 T 12-10-2018 AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 SUPERFAMILY SSF51735 7 253 1.76E-88 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2225 74da3d19ef87f2e95d9ebac2704b3d1e 261 Gene3D G3DSA:3.40.50.720 2 253 9.3E-88 T 12-10-2018 AFE_3033 434511bcceaf873826cda0bd84d24508 342 SUPERFAMILY SSF56112 22 321 2.79E-43 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFE_3033 434511bcceaf873826cda0bd84d24508 342 Gene3D G3DSA:3.90.1200.10 101 339 1.7E-63 T 12-10-2018 AFE_3033 434511bcceaf873826cda0bd84d24508 342 Pfam PF01636 Phosphotransferase enzyme family 38 260 1.4E-24 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFE_3033 434511bcceaf873826cda0bd84d24508 342 Gene3D G3DSA:3.30.200.20 19 100 1.5E-13 T 12-10-2018 AFE_3260 5e9aefa62669e79b5861819262105220 151 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 5 117 1.1E-30 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFE_3260 5e9aefa62669e79b5861819262105220 151 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 5 144 20.893 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFE_3260 5e9aefa62669e79b5861819262105220 151 SUPERFAMILY SSF81330 15 134 1.05E-31 T 12-10-2018 IPR036019 Gated mechanosensitive channel AFE_3260 5e9aefa62669e79b5861819262105220 151 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 5 118 7.3E-36 T 12-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L AFE_3260 5e9aefa62669e79b5861819262105220 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 8 22 1.2E-8 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFE_3260 5e9aefa62669e79b5861819262105220 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 97 105 1.2E-8 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFE_3260 5e9aefa62669e79b5861819262105220 151 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 106 115 1.2E-8 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFE_3260 5e9aefa62669e79b5861819262105220 151 Gene3D G3DSA:1.10.1200.120 5 135 2.0E-31 T 12-10-2018 IPR036019 Gated mechanosensitive channel AFE_3026 77043811218f13b5441de39a28dd3137 241 Gene3D G3DSA:3.40.50.300 3 241 7.0E-68 T 12-10-2018 AFE_3026 77043811218f13b5441de39a28dd3137 241 SMART SM00382 29 216 5.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_3026 77043811218f13b5441de39a28dd3137 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 5 240 1.3E-112 T 12-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 AFE_3026 77043811218f13b5441de39a28dd3137 241 Pfam PF00005 ABC transporter 21 166 2.2E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_3026 77043811218f13b5441de39a28dd3137 241 SUPERFAMILY SSF52540 4 236 1.85E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3026 77043811218f13b5441de39a28dd3137 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_0962 d1eb878c38fbf2d65a756b68669e7c4c 692 Gene3D G3DSA:3.90.550.10 92 326 2.1E-17 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0962 d1eb878c38fbf2d65a756b68669e7c4c 692 Pfam PF00535 Glycosyl transferase family 2 103 284 5.7E-14 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFE_0962 d1eb878c38fbf2d65a756b68669e7c4c 692 SUPERFAMILY SSF53448 98 384 6.56E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_3282 fe033cb72cad8917aabeccbf8cf5aab3 136 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 20 117 5.0E-17 T 12-10-2018 IPR006894 HupH hydrogenase expression protein, C-terminal AFE_3282 fe033cb72cad8917aabeccbf8cf5aab3 136 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 15 129 1.1E-35 T 12-10-2018 IPR006894 HupH hydrogenase expression protein, C-terminal AFE_3282 fe033cb72cad8917aabeccbf8cf5aab3 136 Gene3D G3DSA:3.30.1370.140 13 110 2.9E-30 T 12-10-2018 IPR038527 HupH, C-terminal domain superfamily AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 48 219 8.9E-50 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 331 414 1.5E-28 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 SUPERFAMILY SSF142984 241 324 3.01E-24 T 12-10-2018 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 SUPERFAMILY SSF142019 5 240 2.09E-87 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 14 415 2.0E-196 T 12-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 342 353 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 Gene3D G3DSA:3.40.50.11540 53 230 2.4E-82 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 SUPERFAMILY SSF140490 325 423 1.09E-35 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 Pfam PF10531 SLBB domain 243 291 2.9E-16 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 SMART SM00928 329 374 4.0E-26 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 Gene3D G3DSA:3.10.20.600 232 326 6.1E-33 T 12-10-2018 AFE_2625 2ca377e6c3f2be173fee48e4a54068e7 427 Gene3D G3DSA:1.20.1440.230 327 423 5.6E-32 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2375 5432adc5a79b5173299540f8546c6c99 1054 SMART SM00487 295 502 1.2E-11 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_2375 5432adc5a79b5173299540f8546c6c99 1054 SUPERFAMILY SSF52540 314 715 1.83E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2375 5432adc5a79b5173299540f8546c6c99 1054 Gene3D G3DSA:3.40.50.300 582 736 7.1E-27 T 12-10-2018 AFE_2375 5432adc5a79b5173299540f8546c6c99 1054 Pfam PF00271 Helicase conserved C-terminal domain 629 704 1.4E-6 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_2375 5432adc5a79b5173299540f8546c6c99 1054 SMART SM00490 612 705 4.1E-10 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_2375 5432adc5a79b5173299540f8546c6c99 1054 Pfam PF00270 DEAD/DEAH box helicase 315 466 8.6E-18 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFE_2375 5432adc5a79b5173299540f8546c6c99 1054 Gene3D G3DSA:3.40.50.300 274 496 1.1E-40 T 12-10-2018 AFE_2387 75bf5c38f4ed992f1c480d6be13089e3 256 SUPERFAMILY SSF51556 4 252 6.98E-74 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFE_2387 75bf5c38f4ed992f1c480d6be13089e3 256 PIRSF PIRSF005902 1 255 5.8E-59 T 12-10-2018 IPR001130 TatD family GO:0016788 AFE_2387 75bf5c38f4ed992f1c480d6be13089e3 256 Gene3D G3DSA:3.20.20.140 1 253 2.9E-74 T 12-10-2018 AFE_2387 75bf5c38f4ed992f1c480d6be13089e3 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 4 12 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AFE_2387 75bf5c38f4ed992f1c480d6be13089e3 256 Pfam PF01026 TatD related DNase 5 251 2.2E-61 T 12-10-2018 IPR001130 TatD family GO:0016788 AFE_1197 694fe3a21560ff5eac046fc102e2a8ac 279 SUPERFAMILY SSF102405 111 158 4.43E-7 T 12-10-2018 AFE_1197 694fe3a21560ff5eac046fc102e2a8ac 279 Gene3D G3DSA:3.40.50.450 107 217 1.1E-5 T 12-10-2018 AFE_1197 694fe3a21560ff5eac046fc102e2a8ac 279 Pfam PF14216 Domain of unknown function (DUF4326) 13 88 2.7E-18 T 12-10-2018 IPR025475 Protein of unknown function DUF4326) AFE_0551 1208f42f5e0bd0701ef58494f503c398 282 Gene3D G3DSA:3.60.110.10 6 282 6.2E-93 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFE_0551 1208f42f5e0bd0701ef58494f503c398 282 SUPERFAMILY SSF56317 14 274 1.31E-78 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFE_0551 1208f42f5e0bd0701ef58494f503c398 282 Pfam PF00795 Carbon-nitrogen hydrolase 16 264 7.5E-54 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFE_0569 2b62919a1a65c695b147278b3767b1ea 281 Pfam PF03734 L,D-transpeptidase catalytic domain 67 225 3.9E-20 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFE_0569 2b62919a1a65c695b147278b3767b1ea 281 Gene3D G3DSA:2.40.440.10 34 272 7.3E-22 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFE_0569 2b62919a1a65c695b147278b3767b1ea 281 SUPERFAMILY SSF141523 63 226 4.97E-19 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFE_0522 12c340cdc249a471561d4f6034aabf61 258 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 155 176 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 AFE_0522 12c340cdc249a471561d4f6034aabf61 258 SUPERFAMILY SSF109998 23 156 2.39E-15 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily AFE_0522 12c340cdc249a471561d4f6034aabf61 258 Gene3D G3DSA:3.10.50.40 121 242 4.2E-29 T 12-10-2018 AFE_0522 12c340cdc249a471561d4f6034aabf61 258 SUPERFAMILY SSF54534 127 214 2.75E-25 T 12-10-2018 AFE_0522 12c340cdc249a471561d4f6034aabf61 258 Pfam PF13616 PPIC-type PPIASE domain 123 216 3.0E-24 T 12-10-2018 AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 Pfam PF08238 Sel1 repeat 243 277 6.3E-4 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 Pfam PF08238 Sel1 repeat 134 169 3.0E-5 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 Pfam PF08238 Sel1 repeat 107 129 12.0 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 Pfam PF08238 Sel1 repeat 280 313 0.026 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 Pfam PF08238 Sel1 repeat 206 241 3.0E-4 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 Pfam PF08238 Sel1 repeat 314 348 0.0024 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 Pfam PF08238 Sel1 repeat 170 205 5.5E-11 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 Gene3D G3DSA:1.25.40.10 207 361 5.6E-39 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 SMART SM00671 134 169 3.3E-6 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 SMART SM00671 170 205 6.3E-11 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 SMART SM00671 206 241 6.0E-6 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 SMART SM00671 314 349 1.2E-4 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 SMART SM00671 278 313 1.3E-6 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 SMART SM00671 102 133 41.0 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 SMART SM00671 242 277 2.3E-7 T 12-10-2018 IPR006597 Sel1-like repeat AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 SUPERFAMILY SSF81901 105 352 2.22E-56 T 12-10-2018 AFE_2686 c3cff3b4fb4ada5de7be1137d6f7f2e8 365 Gene3D G3DSA:1.25.40.10 88 206 3.0E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_3129 e44adb7b59af224e98ec1b1062cd5ff8 467 Pfam PF00654 Voltage gated chloride channel 101 446 3.6E-61 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_3129 e44adb7b59af224e98ec1b1062cd5ff8 467 SUPERFAMILY SSF81340 29 459 1.83E-74 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 AFE_3129 e44adb7b59af224e98ec1b1062cd5ff8 467 Gene3D G3DSA:1.10.3080.10 29 466 1.6E-69 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 AFE_3129 e44adb7b59af224e98ec1b1062cd5ff8 467 PRINTS PR00762 Chloride channel signature 397 413 1.1E-15 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_3129 e44adb7b59af224e98ec1b1062cd5ff8 467 PRINTS PR00762 Chloride channel signature 194 213 1.1E-15 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_3129 e44adb7b59af224e98ec1b1062cd5ff8 467 PRINTS PR00762 Chloride channel signature 143 162 1.1E-15 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_3129 e44adb7b59af224e98ec1b1062cd5ff8 467 PRINTS PR00762 Chloride channel signature 362 382 1.1E-15 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_3129 e44adb7b59af224e98ec1b1062cd5ff8 467 PRINTS PR00762 Chloride channel signature 415 434 1.1E-15 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_2584 447ae698c56541dc83c41d455dd52230 242 SMART SM00563 72 186 4.2E-31 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFE_2584 447ae698c56541dc83c41d455dd52230 242 Pfam PF01553 Acyltransferase 59 183 2.0E-22 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFE_2584 447ae698c56541dc83c41d455dd52230 242 SUPERFAMILY SSF69593 16 235 1.19E-38 T 12-10-2018 AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 SUPERFAMILY SSF53067 5 121 1.1E-27 T 12-10-2018 AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 Gene3D G3DSA:3.30.420.40 5 313 3.8E-116 T 12-10-2018 AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 SUPERFAMILY SSF53067 102 307 1.2E-39 T 12-10-2018 AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 6 305 1.9E-104 T 12-10-2018 IPR017861 Kae1/TsaD family AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 Gene3D G3DSA:3.30.420.40 128 292 3.8E-116 T 12-10-2018 AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 Pfam PF00814 Glycoprotease family 26 305 2.0E-91 T 12-10-2018 IPR000905 Gcp-like domain AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 5 311 4.4E-122 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 6 19 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 153 174 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 263 272 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 130 142 4.0E-51 T 12-10-2018 IPR017861 Kae1/TsaD family AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 12-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 AFE_0123 a905b0741cc7bbc7c8fd6c1a59f15662 335 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 3 330 61.161 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 AFE_1806 ce89fe4f3f4fec4b32b9c9752a76fbe2 133 Gene3D G3DSA:1.25.40.10 11 123 4.6E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1806 ce89fe4f3f4fec4b32b9c9752a76fbe2 133 SUPERFAMILY SSF81901 29 105 4.71E-5 T 12-10-2018 AFE_1666 f5a5552d60f121a462a65e28b3481b30 445 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 270 430 3.5E-37 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain AFE_1666 f5a5552d60f121a462a65e28b3481b30 445 Gene3D G3DSA:3.40.50.10840 8 249 3.7E-17 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily AFE_1666 f5a5552d60f121a462a65e28b3481b30 445 SUPERFAMILY SSF142764 8 439 1.07E-81 T 12-10-2018 AFE_1666 f5a5552d60f121a462a65e28b3481b30 445 Pfam PF07005 Putative sugar-binding N-terminal domain 8 246 9.1E-57 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain AFE_1666 f5a5552d60f121a462a65e28b3481b30 445 Gene3D G3DSA:3.40.980.20 256 442 2.5E-12 T 12-10-2018 AFE_3046 adf517b26453db02bac96531af1ea791 253 Pfam PF00977 Histidine biosynthesis protein 5 233 9.8E-87 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 AFE_3046 adf517b26453db02bac96531af1ea791 253 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 250 1.1E-107 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AFE_3046 adf517b26453db02bac96531af1ea791 253 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 250 47.56 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AFE_3046 adf517b26453db02bac96531af1ea791 253 SUPERFAMILY SSF51366 2 250 1.02E-81 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFE_3046 adf517b26453db02bac96531af1ea791 253 Gene3D G3DSA:3.20.20.70 1 253 2.5E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_3177 e410efa7f9758a20e569680dd8f31cd4 494 SUPERFAMILY SSF53098 158 301 4.17E-9 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_3177 e410efa7f9758a20e569680dd8f31cd4 494 Pfam PF00665 Integrase core domain 131 257 1.5E-13 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFE_3177 e410efa7f9758a20e569680dd8f31cd4 494 ProDom PD043187 TRANSPOSASE PLASMID CATALYTIC INTEGRASE DNA-BINDING DNA TRANSPOSITION RECOMBINATION FOR INSERTION 23 134 3.0E-21 T 12-10-2018 AFE_1028 46cc48e0b599ed5d6ceda936f9ac3f7d 297 SUPERFAMILY SSF56024 194 293 2.89E-12 T 12-10-2018 AFE_1028 46cc48e0b599ed5d6ceda936f9ac3f7d 297 SUPERFAMILY SSF56024 3 150 4.26E-24 T 12-10-2018 AFE_1028 46cc48e0b599ed5d6ceda936f9ac3f7d 297 Pfam PF13091 PLD-like domain 190 291 9.5E-12 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFE_1028 46cc48e0b599ed5d6ceda936f9ac3f7d 297 Pfam PF13091 PLD-like domain 13 147 4.0E-18 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFE_1028 46cc48e0b599ed5d6ceda936f9ac3f7d 297 Gene3D G3DSA:3.30.870.10 3 150 2.0E-25 T 12-10-2018 AFE_1028 46cc48e0b599ed5d6ceda936f9ac3f7d 297 Gene3D G3DSA:3.30.870.10 169 294 3.0E-13 T 12-10-2018 AFE_0012 d3650826152136421cd71f9de5f37e0e 269 Pfam PF13614 AAA domain 3 156 2.1E-21 T 12-10-2018 IPR025669 AAA domain AFE_0012 d3650826152136421cd71f9de5f37e0e 269 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 266 2.0E-106 T 12-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 AFE_0012 d3650826152136421cd71f9de5f37e0e 269 Gene3D G3DSA:3.40.50.300 1 259 2.8E-72 T 12-10-2018 AFE_0012 d3650826152136421cd71f9de5f37e0e 269 PIRSF PIRSF003092 1 269 1.9E-89 T 12-10-2018 IPR025501 ATP binding protein MinD AFE_0012 d3650826152136421cd71f9de5f37e0e 269 SUPERFAMILY SSF52540 2 267 5.35E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3302 6878246b1db424a28754502e5cb46cb7 131 SUPERFAMILY SSF54197 3 130 2.32E-32 T 12-10-2018 IPR036265 HIT-like superfamily AFE_3302 6878246b1db424a28754502e5cb46cb7 131 Pfam PF01230 HIT domain 11 99 2.2E-17 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFE_3302 6878246b1db424a28754502e5cb46cb7 131 PRINTS PR00332 Histidine triad family signature 87 97 8.7E-16 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFE_3302 6878246b1db424a28754502e5cb46cb7 131 PRINTS PR00332 Histidine triad family signature 4 20 8.7E-16 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFE_3302 6878246b1db424a28754502e5cb46cb7 131 PRINTS PR00332 Histidine triad family signature 25 43 8.7E-16 T 12-10-2018 IPR001310 Histidine triad (HIT) protein AFE_3302 6878246b1db424a28754502e5cb46cb7 131 Gene3D G3DSA:3.30.428.10 1 130 1.3E-32 T 12-10-2018 IPR036265 HIT-like superfamily AFE_2080 96133a6b813a3979f935063eaf36a08f 605 Gene3D G3DSA:3.40.1750.10 180 491 7.5E-133 T 12-10-2018 AFE_2080 96133a6b813a3979f935063eaf36a08f 605 PIRSF PIRSF001217 6 565 3.1E-150 T 12-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 AFE_2080 96133a6b813a3979f935063eaf36a08f 605 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 318 534 4.1E-51 T 12-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 AFE_2080 96133a6b813a3979f935063eaf36a08f 605 Gene3D G3DSA:3.90.226.10 89 307 7.5E-133 T 12-10-2018 AFE_2080 96133a6b813a3979f935063eaf36a08f 605 Gene3D G3DSA:3.90.226.10 308 534 7.5E-133 T 12-10-2018 AFE_2080 96133a6b813a3979f935063eaf36a08f 605 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 24 549 7.8E-128 T 12-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 AFE_2080 96133a6b813a3979f935063eaf36a08f 605 Pfam PF01343 Peptidase family S49 385 535 3.7E-45 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 AFE_2080 96133a6b813a3979f935063eaf36a08f 605 Pfam PF01343 Peptidase family S49 132 276 5.9E-26 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 AFE_2080 96133a6b813a3979f935063eaf36a08f 605 SUPERFAMILY SSF52096 314 521 2.11E-35 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFE_2080 96133a6b813a3979f935063eaf36a08f 605 SUPERFAMILY SSF52096 87 278 8.29E-21 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 SUPERFAMILY SSF52540 1 562 3.02E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 ProSitePatterns PS00211 ABC transporters family signature. 822 836 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 Gene3D G3DSA:1.10.8.280 285 396 5.0E-242 T 12-10-2018 AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 Gene3D G3DSA:1.20.1580.10 684 822 2.2E-142 T 12-10-2018 AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 Gene3D G3DSA:3.30.190.20 128 242 5.0E-242 T 12-10-2018 AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 Gene3D G3DSA:3.40.50.300 6 587 5.0E-242 T 12-10-2018 AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 Gene3D G3DSA:1.20.1580.10 90 485 5.0E-242 T 12-10-2018 AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 932 22.327 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 917 0.0 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 Gene3D G3DSA:3.40.50.300 609 928 2.2E-142 T 12-10-2018 AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 SUPERFAMILY SSF52540 614 903 1.84E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2847 62b0592af5cc9b493d399f58bfbfd615 934 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_1436 cdd4735f7fba51dfed974662c82d248b 339 Gene3D G3DSA:3.40.190.10 100 276 1.8E-112 T 12-10-2018 AFE_1436 cdd4735f7fba51dfed974662c82d248b 339 SUPERFAMILY SSF53850 25 335 5.07E-91 T 12-10-2018 AFE_1436 cdd4735f7fba51dfed974662c82d248b 339 PIRSF PIRSF002756 8 337 4.6E-99 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFE_1436 cdd4735f7fba51dfed974662c82d248b 339 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 26 334 7.0E-108 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 AFE_1436 cdd4735f7fba51dfed974662c82d248b 339 Pfam PF12849 PBP superfamily domain 21 305 3.3E-59 T 12-10-2018 IPR024370 PBP domain AFE_1436 cdd4735f7fba51dfed974662c82d248b 339 Gene3D G3DSA:3.40.190.10 29 324 1.8E-112 T 12-10-2018 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 PIRSF PIRSF000149 1 338 3.4E-135 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 161 316 2.0E-62 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 SMART SM00846 3 156 4.7E-95 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 Gene3D G3DSA:3.40.50.720 4 328 4.1E-145 T 12-10-2018 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 SUPERFAMILY SSF51735 1 174 3.21E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 105 2.3E-36 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 328 3.4E-130 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 Gene3D G3DSA:3.30.360.10 155 318 4.1E-145 T 12-10-2018 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 SUPERFAMILY SSF55347 156 317 4.68E-69 T 12-10-2018 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 233 250 6.4E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 273 288 6.4E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 177 193 6.4E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 150 168 6.4E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_3251 290944304c8e314e621fe215dc0cb6f0 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 6.4E-39 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFE_0691 c56b62cae5a90dd05e40358e1be80664 79 Gene3D G3DSA:1.10.10.10 3 79 4.4E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0691 c56b62cae5a90dd05e40358e1be80664 79 SUPERFAMILY SSF46785 3 74 1.3E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1541 07bed2c9964f293c7edb7c30c0966975 101 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 84 2.4E-9 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFE_1541 07bed2c9964f293c7edb7c30c0966975 101 Gene3D G3DSA:3.10.20.30 1 97 1.7E-22 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_1541 07bed2c9964f293c7edb7c30c0966975 101 SUPERFAMILY SSF54292 2 95 1.66E-20 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 SUPERFAMILY SSF81665 11 842 7.59E-96 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 Pfam PF00702 haloacid dehalogenase-like hydrolase 325 605 4.1E-15 T 12-10-2018 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 Gene3D G3DSA:3.40.50.1000 326 338 2.8E-87 T 12-10-2018 IPR023214 HAD superfamily AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 559 681 1.4E-27 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 90 365 4.1E-36 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 PRINTS PR01836 Magnesium-transporting ATPase signature 242 258 2.0E-43 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 PRINTS PR01836 Magnesium-transporting ATPase signature 750 771 2.0E-43 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 PRINTS PR01836 Magnesium-transporting ATPase signature 363 376 2.0E-43 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 PRINTS PR01836 Magnesium-transporting ATPase signature 259 278 2.0E-43 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 PRINTS PR01836 Magnesium-transporting ATPase signature 649 664 2.0E-43 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 PRINTS PR01836 Magnesium-transporting ATPase signature 799 820 2.0E-43 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 PRINTS PR01836 Magnesium-transporting ATPase signature 719 735 2.0E-43 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 PRINTS PR01836 Magnesium-transporting ATPase signature 699 712 2.0E-43 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 PRINTS PR01836 Magnesium-transporting ATPase signature 667 678 2.0E-43 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 Gene3D G3DSA:3.40.1110.10 383 499 1.3E-54 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 331 337 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 SMART SM00831 10 83 1.4E-22 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 SUPERFAMILY SSF81653 122 229 6.67E-28 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 Pfam PF00690 Cation transporter/ATPase, N-terminus 12 78 2.3E-15 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 Pfam PF00122 E1-E2 ATPase 120 309 7.8E-46 T 12-10-2018 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 18 842 5.3E-273 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 Gene3D G3DSA:1.20.1110.10 61 325 2.8E-87 T 12-10-2018 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 Gene3D G3DSA:2.70.150.10 27 232 2.8E-87 T 12-10-2018 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 Pfam PF00689 Cation transporting ATPase, C-terminus 674 836 7.5E-13 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 SUPERFAMILY SSF56784 327 689 1.11E-37 T 12-10-2018 IPR036412 HAD-like superfamily AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 Gene3D G3DSA:1.20.1110.10 630 690 1.3E-54 T 12-10-2018 AFE_2327 f70562f5ec7b3d3d6254a32e733c9375 847 Gene3D G3DSA:3.40.50.1000 500 629 1.3E-54 T 12-10-2018 IPR023214 HAD superfamily AFE_1413 95d79342464de373fea35268994b753b 109 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 8 107 1.7E-39 T 12-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 AFE_1413 95d79342464de373fea35268994b753b 109 SUPERFAMILY SSF89447 7 51 7.5E-6 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFE_1413 95d79342464de373fea35268994b753b 109 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 9 92 3.0E-35 T 12-10-2018 AFE_1490 7242fa509a2d271965844ea172c83558 327 Pfam PF01032 FecCD transport family 14 320 6.9E-77 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFE_1490 7242fa509a2d271965844ea172c83558 327 Gene3D G3DSA:1.10.3470.10 4 326 5.3E-88 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFE_1490 7242fa509a2d271965844ea172c83558 327 SUPERFAMILY SSF81345 3 320 2.09E-70 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 191 28.647 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 Pfam PF01330 RuvA N terminal domain 1 62 1.0E-17 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 SUPERFAMILY SSF50249 1 63 6.28E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 190 8.9E-48 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 Gene3D G3DSA:2.40.50.140 1 66 1.1E-22 T 12-10-2018 AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 SUPERFAMILY SSF47781 65 133 2.54E-20 T 12-10-2018 IPR010994 RuvA domain 2-like AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 Pfam PF07499 RuvA, C-terminal domain 147 191 5.8E-13 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 SMART SM00278 108 127 0.0028 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 SMART SM00278 73 92 190.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 Gene3D G3DSA:1.10.8.10 145 190 6.6E-12 T 12-10-2018 AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 Gene3D G3DSA:1.10.150.20 67 137 1.2E-25 T 12-10-2018 AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 SUPERFAMILY SSF46929 147 192 3.01E-8 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily AFE_0061 e73fbad87e0ebb96c1610f265e9536d4 193 Pfam PF14520 Helix-hairpin-helix domain 72 130 6.9E-16 T 12-10-2018 AFE_1976 8127d192f2da2ecac8e0536a7ccce88b 89 Pfam PF02609 Exonuclease VII small subunit 21 71 1.8E-15 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFE_1976 8127d192f2da2ecac8e0536a7ccce88b 89 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 21 75 5.6E-18 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFE_1976 8127d192f2da2ecac8e0536a7ccce88b 89 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 16 60 3.0E-5 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFE_1976 8127d192f2da2ecac8e0536a7ccce88b 89 SUPERFAMILY SSF116842 18 78 1.31E-15 T 12-10-2018 AFE_1976 8127d192f2da2ecac8e0536a7ccce88b 89 PIRSF PIRSF006488 8 89 2.6E-17 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFE_1976 8127d192f2da2ecac8e0536a7ccce88b 89 Gene3D G3DSA:1.10.287.1040 15 88 2.9E-18 T 12-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 AFE_1976 8127d192f2da2ecac8e0536a7ccce88b 89 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 20 80 12.937 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 Gene3D G3DSA:1.10.10.60 414 480 1.7E-15 T 12-10-2018 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 Gene3D G3DSA:1.10.8.60 336 413 5.8E-22 T 12-10-2018 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 SUPERFAMILY SSF52172 26 210 5.69E-20 T 12-10-2018 IPR011006 CheY-like superfamily AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 189 202 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 Gene3D G3DSA:3.40.50.2300 9 145 7.6E-14 T 12-10-2018 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 251 266 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 441 458 8.8E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 458 478 8.8E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 SUPERFAMILY SSF52540 165 407 1.15E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 Gene3D G3DSA:3.40.50.300 151 335 2.6E-61 T 12-10-2018 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 Pfam PF02954 Bacterial regulatory protein, Fis family 436 475 1.5E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 SMART SM00382 185 328 8.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 SUPERFAMILY SSF46689 379 477 2.55E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 Pfam PF00158 Sigma-54 interaction domain 168 331 3.8E-61 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 378 387 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_0700 7751ffd9b4e87908286923ff242c6b5e 482 Pfam PF00072 Response regulator receiver domain 33 113 2.6E-7 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_3162 3dca841d28f5580a5abc1e7f41616120 161 SUPERFAMILY SSF55729 1 156 1.18E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_3162 3dca841d28f5580a5abc1e7f41616120 161 Pfam PF00583 Acetyltransferase (GNAT) family 46 133 5.5E-14 T 12-10-2018 IPR000182 GNAT domain AFE_3162 3dca841d28f5580a5abc1e7f41616120 161 Gene3D G3DSA:3.40.630.30 1 158 2.6E-40 T 12-10-2018 AFE_3258 fd8a530659a8b13512ad0d3be5971686 316 Gene3D G3DSA:3.40.1010.20 97 194 2.8E-110 T 12-10-2018 AFE_3258 fd8a530659a8b13512ad0d3be5971686 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 284 38.255 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFE_3258 fd8a530659a8b13512ad0d3be5971686 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 281 1.1E-97 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFE_3258 fd8a530659a8b13512ad0d3be5971686 316 Pfam PF02401 LytB protein 3 280 2.0E-91 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFE_3258 fd8a530659a8b13512ad0d3be5971686 316 Gene3D G3DSA:3.40.1010.20 6 280 2.8E-110 T 12-10-2018 AFE_3258 fd8a530659a8b13512ad0d3be5971686 316 Gene3D G3DSA:3.40.50.11270 12 96 2.8E-110 T 12-10-2018 AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 Gene3D G3DSA:2.40.340.10 335 404 8.9E-136 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 SUPERFAMILY SSF63867 334 412 1.27E-18 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 184 320 4.7E-31 T 12-10-2018 IPR001453 MoaB/Mog domain AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 Gene3D G3DSA:3.90.105.10 34 181 8.9E-136 T 12-10-2018 AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 Pfam PF03454 MoeA C-terminal region (domain IV) 339 409 3.1E-13 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 Gene3D G3DSA:3.40.980.10 182 334 8.9E-136 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 SUPERFAMILY SSF53218 184 327 1.7E-43 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 Pfam PF00994 Probable molybdopterin binding domain 188 322 5.4E-27 T 12-10-2018 IPR001453 MoaB/Mog domain AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 Pfam PF03453 MoeA N-terminal region (domain I and II) 16 174 2.2E-44 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 SUPERFAMILY SSF63882 16 183 5.23E-52 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 SMART SM00852 187 324 4.5E-43 T 12-10-2018 IPR001453 MoaB/Mog domain AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 Gene3D G3DSA:2.170.190.11 58 148 8.9E-136 T 12-10-2018 AFE_2078 d6c3b577ed417d09d7033b336dd57d66 413 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 260 293 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 AFE_2533 818819826e24f0bc6d7a738212dce711 381 Pfam PF00248 Aldo/keto reductase family 47 373 1.0E-18 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFE_2533 818819826e24f0bc6d7a738212dce711 381 SUPERFAMILY SSF51430 37 373 3.67E-33 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFE_2533 818819826e24f0bc6d7a738212dce711 381 Gene3D G3DSA:3.20.20.100 33 379 1.3E-26 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFE_1817 e598b5199fa373b80a5a098ca9d17b53 320 Pfam PF13469 Sulfotransferase family 7 201 2.9E-17 T 12-10-2018 AFE_1817 e598b5199fa373b80a5a098ca9d17b53 320 SUPERFAMILY SSF52540 4 299 7.97E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1817 e598b5199fa373b80a5a098ca9d17b53 320 Gene3D G3DSA:3.40.50.300 3 236 7.7E-69 T 12-10-2018 AFE_0809 850084ca19abdec5bfabc93d62d5b4a9 782 Gene3D G3DSA:3.90.1170.50 32 153 2.3E-33 T 12-10-2018 AFE_0809 850084ca19abdec5bfabc93d62d5b4a9 782 SUPERFAMILY SSF56003 145 775 3.14E-161 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 AFE_0809 850084ca19abdec5bfabc93d62d5b4a9 782 SUPERFAMILY SSF54665 42 172 2.09E-38 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily AFE_0809 850084ca19abdec5bfabc93d62d5b4a9 782 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 59 153 3.6E-19 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFE_0809 850084ca19abdec5bfabc93d62d5b4a9 782 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 204 715 1.6E-122 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 AFE_0809 850084ca19abdec5bfabc93d62d5b4a9 782 Gene3D G3DSA:3.30.365.20 437 777 4.9E-92 T 12-10-2018 AFE_0809 850084ca19abdec5bfabc93d62d5b4a9 782 Gene3D G3DSA:3.30.365.10 230 322 4.3E-65 T 12-10-2018 AFE_0809 850084ca19abdec5bfabc93d62d5b4a9 782 SMART SM01008 59 153 7.5E-41 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead AFE_0809 850084ca19abdec5bfabc93d62d5b4a9 782 Gene3D G3DSA:3.30.365.10 206 422 4.3E-65 T 12-10-2018 AFE_2351 1ccb628ee56b77f0491ef29e0c62e628 253 Pfam PF01925 Sulfite exporter TauE/SafE 24 250 3.7E-30 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFE_1906 b247be028197cb40cbe3096a5f7a7b5e 314 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 4 313 72.173 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFE_1906 b247be028197cb40cbe3096a5f7a7b5e 314 Gene3D G3DSA:3.40.47.10 2 314 1.0E-131 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_1906 b247be028197cb40cbe3096a5f7a7b5e 314 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 313 9.5E-131 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFE_1906 b247be028197cb40cbe3096a5f7a7b5e 314 SUPERFAMILY SSF53901 6 313 5.23E-74 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_1906 b247be028197cb40cbe3096a5f7a7b5e 314 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 224 313 7.4E-37 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFE_1906 b247be028197cb40cbe3096a5f7a7b5e 314 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 109 186 1.2E-32 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFE_3021 746407d32608153643f3d9e4c38936e4 299 PIRSF PIRSF005052 4 296 1.1E-100 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 AFE_3021 746407d32608153643f3d9e4c38936e4 299 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 4 294 38.445 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 AFE_3021 746407d32608153643f3d9e4c38936e4 299 SUPERFAMILY SSF52540 6 162 1.54E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3021 746407d32608153643f3d9e4c38936e4 299 Pfam PF03668 P-loop ATPase protein family 5 293 4.1E-87 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 AFE_2544 89cffc6877a6d1e49cb592e9014e4b86 353 Pfam PF01494 FAD binding domain 94 159 2.3E-6 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFE_2544 89cffc6877a6d1e49cb592e9014e4b86 353 Pfam PF00890 FAD binding domain 7 75 3.6E-7 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFE_2544 89cffc6877a6d1e49cb592e9014e4b86 353 Gene3D G3DSA:3.50.50.60 3 346 3.8E-64 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2544 89cffc6877a6d1e49cb592e9014e4b86 353 Pfam PF05834 Lycopene cyclase protein 216 285 1.7E-5 T 12-10-2018 AFE_2544 89cffc6877a6d1e49cb592e9014e4b86 353 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 7 286 2.2E-53 T 12-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 AFE_2544 89cffc6877a6d1e49cb592e9014e4b86 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 137 152 1.3E-14 T 12-10-2018 AFE_2544 89cffc6877a6d1e49cb592e9014e4b86 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 254 269 1.3E-14 T 12-10-2018 AFE_2544 89cffc6877a6d1e49cb592e9014e4b86 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.3E-14 T 12-10-2018 AFE_2544 89cffc6877a6d1e49cb592e9014e4b86 353 SUPERFAMILY SSF51905 6 328 3.32E-36 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0777 4aad895b6300bb7109bdf32890ce3f73 288 Gene3D G3DSA:3.30.465.10 2 173 5.1E-51 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFE_0777 4aad895b6300bb7109bdf32890ce3f73 288 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 171 9.9E-43 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 AFE_0777 4aad895b6300bb7109bdf32890ce3f73 288 SMART SM01092 178 281 7.0E-14 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFE_0777 4aad895b6300bb7109bdf32890ce3f73 288 Gene3D G3DSA:3.30.390.50 176 281 4.9E-19 T 12-10-2018 AFE_0777 4aad895b6300bb7109bdf32890ce3f73 288 SUPERFAMILY SSF56176 3 171 1.35E-46 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFE_0777 4aad895b6300bb7109bdf32890ce3f73 288 SUPERFAMILY SSF55447 177 279 1.44E-19 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily AFE_0777 4aad895b6300bb7109bdf32890ce3f73 288 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 180 278 4.1E-16 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal AFE_1408 5b07a0c06dbe4c93a6924eed1e0747e3 280 PIRSF PIRSF005261 2 277 5.0E-57 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 AFE_1408 5b07a0c06dbe4c93a6924eed1e0747e3 280 Pfam PF01430 Hsp33 protein 6 264 3.8E-59 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 AFE_1408 5b07a0c06dbe4c93a6924eed1e0747e3 280 Gene3D G3DSA:3.90.1280.10 217 275 6.6E-19 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 AFE_1408 5b07a0c06dbe4c93a6924eed1e0747e3 280 SUPERFAMILY SSF64397 3 226 1.12E-38 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 AFE_1408 5b07a0c06dbe4c93a6924eed1e0747e3 280 SUPERFAMILY SSF118352 216 273 2.09E-16 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 AFE_1408 5b07a0c06dbe4c93a6924eed1e0747e3 280 Gene3D G3DSA:3.55.30.10 1 169 3.4E-36 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 AFE_0790 03c8830df282117c370e2c32fbbdc090 267 SMART SM00563 93 201 7.6E-19 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFE_0790 03c8830df282117c370e2c32fbbdc090 267 Pfam PF01553 Acyltransferase 86 198 2.1E-13 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFE_0790 03c8830df282117c370e2c32fbbdc090 267 SUPERFAMILY SSF69593 41 248 2.22E-21 T 12-10-2018 AFE_1725 22f43a92702528653899b3f61d9652f0 709 SUPERFAMILY SSF55073 167 324 1.49E-48 T 12-10-2018 IPR029787 Nucleotide cyclase AFE_1725 22f43a92702528653899b3f61d9652f0 709 SMART SM00091 32 101 1.2E-5 T 12-10-2018 IPR000014 PAS domain AFE_1725 22f43a92702528653899b3f61d9652f0 709 Pfam PF13682 Chemoreceptor zinc-binding domain 611 675 1.2E-7 T 12-10-2018 IPR025991 Chemoreceptor zinc-binding domain AFE_1725 22f43a92702528653899b3f61d9652f0 709 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 158 321 3.7E-39 T 12-10-2018 IPR000160 GGDEF domain AFE_1725 22f43a92702528653899b3f61d9652f0 709 SMART SM00086 109 151 5.7E-4 T 12-10-2018 IPR001610 PAC motif AFE_1725 22f43a92702528653899b3f61d9652f0 709 Pfam PF00563 EAL domain 341 573 1.1E-62 T 12-10-2018 IPR001633 EAL domain AFE_1725 22f43a92702528653899b3f61d9652f0 709 Pfam PF08448 PAS fold 38 153 7.0E-19 T 12-10-2018 IPR013656 PAS fold-4 AFE_1725 22f43a92702528653899b3f61d9652f0 709 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 32 154 5.1E-17 T 12-10-2018 IPR000014 PAS domain AFE_1725 22f43a92702528653899b3f61d9652f0 709 SMART SM00267 151 323 2.3E-61 T 12-10-2018 IPR000160 GGDEF domain AFE_1725 22f43a92702528653899b3f61d9652f0 709 Gene3D G3DSA:3.30.450.20 21 149 1.6E-24 T 12-10-2018 AFE_1725 22f43a92702528653899b3f61d9652f0 709 Pfam PF00990 Diguanylate cyclase, GGDEF domain 162 319 1.0E-44 T 12-10-2018 IPR000160 GGDEF domain AFE_1725 22f43a92702528653899b3f61d9652f0 709 SUPERFAMILY SSF141868 343 587 1.44E-72 T 12-10-2018 IPR035919 EAL domain superfamily AFE_1725 22f43a92702528653899b3f61d9652f0 709 SUPERFAMILY SSF55785 19 149 5.41E-23 T 12-10-2018 IPR035965 PAS domain superfamily AFE_1725 22f43a92702528653899b3f61d9652f0 709 Gene3D G3DSA:3.20.20.450 338 592 3.8E-81 T 12-10-2018 IPR035919 EAL domain superfamily AFE_1725 22f43a92702528653899b3f61d9652f0 709 SMART SM00052 333 578 5.8E-85 T 12-10-2018 IPR001633 EAL domain AFE_1725 22f43a92702528653899b3f61d9652f0 709 Gene3D G3DSA:3.30.70.270 156 337 3.6E-55 T 12-10-2018 AFE_0572 094e59997973744fb1162c5a2f345713 264 Hamap MF_00055 MEMO1 family protein . 1 255 46.036 T 12-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 AFE_0572 094e59997973744fb1162c5a2f345713 264 Gene3D G3DSA:3.40.830.10 1 255 1.2E-58 T 12-10-2018 AFE_0572 094e59997973744fb1162c5a2f345713 264 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 1 254 2.1E-78 T 12-10-2018 AFE_0572 094e59997973744fb1162c5a2f345713 264 Pfam PF01875 Memo-like protein 2 252 4.2E-46 T 12-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 AFE_2743 2c356545c58f1d3245140451facec785 288 Gene3D G3DSA:3.10.310.10 6 273 1.9E-98 T 12-10-2018 AFE_2743 2c356545c58f1d3245140451facec785 288 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 12-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFE_2743 2c356545c58f1d3245140451facec785 288 SUPERFAMILY SSF54506 4 278 2.65E-51 T 12-10-2018 AFE_2743 2c356545c58f1d3245140451facec785 288 Pfam PF01678 Diaminopimelate epimerase 6 126 1.3E-28 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFE_2743 2c356545c58f1d3245140451facec785 288 Pfam PF01678 Diaminopimelate epimerase 155 269 2.4E-26 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFE_2743 2c356545c58f1d3245140451facec785 288 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 274 5.3E-83 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFE_2743 2c356545c58f1d3245140451facec785 288 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 277 37.039 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFE_2743 2c356545c58f1d3245140451facec785 288 Gene3D G3DSA:3.10.310.10 118 264 1.9E-98 T 12-10-2018 AFE_1728 dc2b5e5d152d89befd1b87796ff7b924 113 SUPERFAMILY SSF46785 44 93 2.11E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1728 dc2b5e5d152d89befd1b87796ff7b924 113 Gene3D G3DSA:1.10.10.10 8 96 1.3E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0437 d0d38fe4e6dfe52ce42011295afc3a53 173 Gene3D G3DSA:3.30.70.260 1 79 5.8E-17 T 12-10-2018 AFE_0437 d0d38fe4e6dfe52ce42011295afc3a53 173 Gene3D G3DSA:3.30.70.260 89 169 1.7E-11 T 12-10-2018 AFE_0437 d0d38fe4e6dfe52ce42011295afc3a53 173 Pfam PF13740 ACT domain 92 126 1.6E-5 T 12-10-2018 AFE_0437 d0d38fe4e6dfe52ce42011295afc3a53 173 Pfam PF13740 ACT domain 4 74 3.3E-12 T 12-10-2018 AFE_0437 d0d38fe4e6dfe52ce42011295afc3a53 173 SUPERFAMILY SSF55021 4 79 1.87E-13 T 12-10-2018 AFE_0437 d0d38fe4e6dfe52ce42011295afc3a53 173 SUPERFAMILY SSF55021 90 168 5.24E-12 T 12-10-2018 AFE_0663 382397f75ba1c33dbf3a7f208a60a9ed 318 Pfam PF01936 NYN domain 8 162 1.1E-22 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type AFE_0663 382397f75ba1c33dbf3a7f208a60a9ed 318 Gene3D G3DSA:3.40.50.1010 2 165 5.1E-29 T 12-10-2018 AFE_0663 382397f75ba1c33dbf3a7f208a60a9ed 318 Gene3D G3DSA:2.40.50.140 187 279 5.8E-6 T 12-10-2018 AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 PRINTS PR00127 Clp protease catalytic subunit P signature 183 202 9.9E-53 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 PRINTS PR00127 Clp protease catalytic subunit P signature 105 122 9.9E-53 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 PRINTS PR00127 Clp protease catalytic subunit P signature 34 49 9.9E-53 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 PRINTS PR00127 Clp protease catalytic subunit P signature 126 145 9.9E-53 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 PRINTS PR00127 Clp protease catalytic subunit P signature 74 94 9.9E-53 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 18 207 6.5E-102 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 Pfam PF00574 Clp protease 28 207 2.1E-86 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 105 116 - T 12-10-2018 IPR018215 ClpP, Ser active site AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 Gene3D G3DSA:3.90.226.10 8 210 8.4E-83 T 12-10-2018 AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 SUPERFAMILY SSF52096 25 209 2.32E-72 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 127 140 - T 12-10-2018 IPR033135 ClpP, histidine active site AFE_0910 cf147e833d4df66584f13d60efd55ac2 214 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 18 208 43.59 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFE_0796 9b84c9b7934a8b9cd820ab9975ff5303 397 SMART SM00825 Beta-ketoacyl synthase 36 396 1.5E-8 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AFE_0796 9b84c9b7934a8b9cd820ab9975ff5303 397 SUPERFAMILY SSF53901 208 395 2.64E-47 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_0796 9b84c9b7934a8b9cd820ab9975ff5303 397 Gene3D G3DSA:3.40.47.10 9 243 2.0E-33 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_0796 9b84c9b7934a8b9cd820ab9975ff5303 397 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 76 234 8.0E-23 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal AFE_0796 9b84c9b7934a8b9cd820ab9975ff5303 397 Gene3D G3DSA:3.40.47.10 249 392 4.2E-41 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_0796 9b84c9b7934a8b9cd820ab9975ff5303 397 SUPERFAMILY SSF53901 1 235 9.88E-37 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_0796 9b84c9b7934a8b9cd820ab9975ff5303 397 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 153 169 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site AFE_0796 9b84c9b7934a8b9cd820ab9975ff5303 397 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 246 350 1.6E-27 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal AFE_2155 3eb49c492046ae1681b0748809c41580 459 Gene3D G3DSA:3.30.70.150 5 136 6.5E-48 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_2155 3eb49c492046ae1681b0748809c41580 459 SUPERFAMILY SSF54966 2 137 5.1E-46 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_2155 3eb49c492046ae1681b0748809c41580 459 Gene3D G3DSA:3.20.20.110 137 439 2.7E-129 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_2155 3eb49c492046ae1681b0748809c41580 459 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 12 130 4.4E-36 T 12-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_2155 3eb49c492046ae1681b0748809c41580 459 Hamap MF_01339 Ribulose bisphosphate carboxylase [cbbM]. 1 459 78.41 T 12-10-2018 IPR020871 Ribulose bisphosphate carboxylase large subunit, type II GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_2155 3eb49c492046ae1681b0748809c41580 459 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 186 194 - T 12-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_2155 3eb49c492046ae1681b0748809c41580 459 SUPERFAMILY SSF51649 138 455 2.36E-111 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_2155 3eb49c492046ae1681b0748809c41580 459 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 143 440 1.1E-114 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_0245 578b405bbd8509818a74b6146cf05dea 292 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 10 268 33.474 T 12-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 AFE_0245 578b405bbd8509818a74b6146cf05dea 292 Gene3D G3DSA:3.40.50.150 4 202 1.2E-34 T 12-10-2018 AFE_0245 578b405bbd8509818a74b6146cf05dea 292 SUPERFAMILY SSF53335 15 256 9.51E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0245 578b405bbd8509818a74b6146cf05dea 292 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 18 267 5.3E-73 T 12-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 AFE_0245 578b405bbd8509818a74b6146cf05dea 292 Pfam PF08241 Methyltransferase domain 55 151 2.7E-23 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFE_0879 fbf41b57325d8276ffb9aa215db2ed89 223 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 8.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0879 fbf41b57325d8276ffb9aa215db2ed89 223 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 8.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0879 fbf41b57325d8276ffb9aa215db2ed89 223 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 8.8E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0879 fbf41b57325d8276ffb9aa215db2ed89 223 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 69 8.9E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0879 fbf41b57325d8276ffb9aa215db2ed89 223 Gene3D G3DSA:3.40.190.10 85 178 4.7E-23 T 12-10-2018 AFE_0879 fbf41b57325d8276ffb9aa215db2ed89 223 Pfam PF03466 LysR substrate binding domain 96 213 1.0E-17 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_0879 fbf41b57325d8276ffb9aa215db2ed89 223 SUPERFAMILY SSF46785 4 82 4.35E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0879 fbf41b57325d8276ffb9aa215db2ed89 223 SUPERFAMILY SSF53850 92 217 9.95E-20 T 12-10-2018 AFE_0879 fbf41b57325d8276ffb9aa215db2ed89 223 Gene3D G3DSA:1.10.10.10 2 82 2.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_3218 4642583d2e1e3edeeaf5de7bca6d7d8c 311 SUPERFAMILY SSF144083 247 309 3.01E-11 T 12-10-2018 AFE_3218 4642583d2e1e3edeeaf5de7bca6d7d8c 311 Gene3D G3DSA:1.20.58.340 255 311 3.0E-10 T 12-10-2018 AFE_3218 4642583d2e1e3edeeaf5de7bca6d7d8c 311 SUPERFAMILY SSF143865 21 244 9.81E-20 T 12-10-2018 AFE_3218 4642583d2e1e3edeeaf5de7bca6d7d8c 311 Gene3D G3DSA:1.20.58.340 129 253 1.7E-7 T 12-10-2018 AFE_3218 4642583d2e1e3edeeaf5de7bca6d7d8c 311 Pfam PF01544 CorA-like Mg2+ transporter protein 25 307 3.5E-37 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFE_0286 9232927930090bba3cb4470858c92ae3 516 Pfam PF00916 Sulfate permease family 13 399 9.2E-51 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AFE_2475 aeb9cae913c06723a17fe37ab222bcaa 583 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 6 576 1.2E-205 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_2475 aeb9cae913c06723a17fe37ab222bcaa 583 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 577 33.161 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_2475 aeb9cae913c06723a17fe37ab222bcaa 583 Pfam PF03814 Potassium-transporting ATPase A subunit 10 575 7.3E-224 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_2475 aeb9cae913c06723a17fe37ab222bcaa 583 PIRSF PIRSF001294 1 579 2.0E-218 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_0681 260de316e2875be4616bed588532997d 299 Pfam PF01734 Patatin-like phospholipase 5 165 2.1E-19 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFE_0681 260de316e2875be4616bed588532997d 299 Gene3D G3DSA:3.40.1090.10 1 111 3.0E-21 T 12-10-2018 AFE_0681 260de316e2875be4616bed588532997d 299 SUPERFAMILY SSF52151 2 292 2.07E-49 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFE_0938 b5cce809f4f1ca76154b72c719331f42 265 Gene3D G3DSA:3.40.50.700 4 167 3.3E-38 T 12-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily AFE_0938 b5cce809f4f1ca76154b72c719331f42 265 SUPERFAMILY SSF56770 4 217 2.35E-41 T 12-10-2018 AFE_0938 b5cce809f4f1ca76154b72c719331f42 265 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 153 1.0E-23 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_0851 06977457e745d8206deddea9fe55fb38 186 SUPERFAMILY SSF50104 3 64 1.62E-17 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFE_0851 06977457e745d8206deddea9fe55fb38 186 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site AFE_0851 06977457e745d8206deddea9fe55fb38 186 SMART SM01185 68 122 1.2E-22 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 AFE_0851 06977457e745d8206deddea9fe55fb38 186 Gene3D G3DSA:2.40.50.140 65 128 4.1E-22 T 12-10-2018 AFE_0851 06977457e745d8206deddea9fe55fb38 186 Gene3D G3DSA:2.40.50.140 129 186 6.7E-23 T 12-10-2018 AFE_0851 06977457e745d8206deddea9fe55fb38 186 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 60 3.1E-22 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like AFE_0851 06977457e745d8206deddea9fe55fb38 186 SUPERFAMILY SSF50249 130 186 5.48E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0851 06977457e745d8206deddea9fe55fb38 186 Gene3D G3DSA:2.30.30.30 3 64 5.2E-22 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFE_0851 06977457e745d8206deddea9fe55fb38 186 Hamap MF_00141 Elongation factor P [efp]. 2 186 44.033 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 AFE_0851 06977457e745d8206deddea9fe55fb38 186 TIGRFAM TIGR00038 efp: translation elongation factor P 4 186 8.9E-73 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 AFE_0851 06977457e745d8206deddea9fe55fb38 186 Pfam PF09285 Elongation factor P, C-terminal 130 185 1.5E-23 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 AFE_0851 06977457e745d8206deddea9fe55fb38 186 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 122 1.3E-18 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 AFE_0851 06977457e745d8206deddea9fe55fb38 186 PIRSF PIRSF005901 1 186 1.3E-64 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP AFE_0851 06977457e745d8206deddea9fe55fb38 186 SMART SM00841 130 185 1.8E-28 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 AFE_0851 06977457e745d8206deddea9fe55fb38 186 SUPERFAMILY SSF50249 66 127 7.71E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1489 dde9c0bcc93f1c762b5ed24f7e4d0b9e 343 Gene3D G3DSA:3.40.50.1980 24 157 3.5E-38 T 12-10-2018 AFE_1489 dde9c0bcc93f1c762b5ed24f7e4d0b9e 343 Gene3D G3DSA:1.20.58.2180 163 335 1.1E-48 T 12-10-2018 AFE_1489 dde9c0bcc93f1c762b5ed24f7e4d0b9e 343 Pfam PF01497 Periplasmic binding protein 98 284 7.6E-22 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain AFE_1489 dde9c0bcc93f1c762b5ed24f7e4d0b9e 343 Gene3D G3DSA:3.40.50.1980 187 290 1.1E-48 T 12-10-2018 AFE_1489 dde9c0bcc93f1c762b5ed24f7e4d0b9e 343 SUPERFAMILY SSF53807 27 313 2.75E-46 T 12-10-2018 AFE_1222 ff23fc5683c3122f35624e532ae92893 237 SUPERFAMILY SSF69917 53 228 1.12E-9 T 12-10-2018 IPR020080 Outer membrane adhesin/peptidase omptin GO:0004190 AFE_1222 ff23fc5683c3122f35624e532ae92893 237 Gene3D G3DSA:2.40.128.130 10 237 1.7E-7 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily AFE_1222 ff23fc5683c3122f35624e532ae92893 237 Pfam PF13505 Outer membrane protein beta-barrel domain 11 153 4.9E-7 T 12-10-2018 IPR027385 Outer membrane protein beta-barrel AFE_1301 221bb6e0783ad03372c69f5e9a23d734 339 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 135 252 1.9E-11 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 AFE_1301 221bb6e0783ad03372c69f5e9a23d734 339 SUPERFAMILY SSF52402 28 249 3.32E-20 T 12-10-2018 AFE_1301 221bb6e0783ad03372c69f5e9a23d734 339 Gene3D G3DSA:3.40.50.620 19 261 3.8E-33 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0218 a0b81ce6108629a38345cbe701be514d 456 SUPERFAMILY SSF81301 7 132 8.07E-17 T 12-10-2018 AFE_0218 a0b81ce6108629a38345cbe701be514d 456 Gene3D G3DSA:3.30.460.10 5 134 3.5E-17 T 12-10-2018 AFE_0218 a0b81ce6108629a38345cbe701be514d 456 Gene3D G3DSA:1.10.3090.10 135 426 1.1E-36 T 12-10-2018 AFE_0218 a0b81ce6108629a38345cbe701be514d 456 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 160 220 2.1E-9 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFE_0218 a0b81ce6108629a38345cbe701be514d 456 Pfam PF01743 Poly A polymerase head domain 100 135 7.6E-7 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFE_0218 a0b81ce6108629a38345cbe701be514d 456 SUPERFAMILY SSF81891 133 434 2.22E-38 T 12-10-2018 AFE_0218 a0b81ce6108629a38345cbe701be514d 456 Pfam PF01966 HD domain 238 359 1.2E-4 T 12-10-2018 IPR006674 HD domain AFE_0066 102cdc7174aa93372f8728b31fb041b0 317 SUPERFAMILY SSF74653 233 298 2.49E-8 T 12-10-2018 AFE_0066 102cdc7174aa93372f8728b31fb041b0 317 Pfam PF13103 TonB C terminal 229 294 1.2E-10 T 12-10-2018 AFE_0066 102cdc7174aa93372f8728b31fb041b0 317 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 250 305 6.5E-9 T 12-10-2018 IPR006260 TonB/TolA, C-terminal AFE_0066 102cdc7174aa93372f8728b31fb041b0 317 TIGRFAM TIGR02794 tolA_full: protein TolA 8 303 8.9E-34 T 12-10-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0016021|GO:0043213 AFE_0066 102cdc7174aa93372f8728b31fb041b0 317 Gene3D G3DSA:3.30.1150.10 194 316 1.5E-18 T 12-10-2018 AFE_1887 b58d69a0746850e3bfbbd4b89df4ee87 290 SUPERFAMILY SSF117892 53 189 9.29E-25 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily AFE_1887 b58d69a0746850e3bfbbd4b89df4ee87 290 TIGRFAM TIGR01932 hflC: HflC protein 142 281 1.3E-44 T 12-10-2018 IPR010200 HflC GO:0016021|GO:0052547 AFE_1887 b58d69a0746850e3bfbbd4b89df4ee87 290 Gene3D G3DSA:3.30.479.30 50 185 6.5E-17 T 12-10-2018 AFE_1887 b58d69a0746850e3bfbbd4b89df4ee87 290 PIRSF PIRSF005651 1 289 1.2E-86 T 12-10-2018 IPR010200 HflC GO:0016021|GO:0052547 AFE_1887 b58d69a0746850e3bfbbd4b89df4ee87 290 SMART SM00244 21 183 1.1E-26 T 12-10-2018 IPR001107 Band 7 domain AFE_1887 b58d69a0746850e3bfbbd4b89df4ee87 290 Pfam PF01145 SPFH domain / Band 7 family 25 199 8.3E-27 T 12-10-2018 IPR001107 Band 7 domain AFE_1480 9280e8240c9556acfb54efc901bd2b4c 280 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 162 182 - T 12-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFE_1480 9280e8240c9556acfb54efc901bd2b4c 280 Pfam PF01012 Electron transfer flavoprotein domain 23 193 7.0E-48 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFE_1480 9280e8240c9556acfb54efc901bd2b4c 280 PIRSF PIRSF000090 1 270 5.0E-89 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFE_1480 9280e8240c9556acfb54efc901bd2b4c 280 SUPERFAMILY SSF52402 1 264 1.95E-74 T 12-10-2018 AFE_1480 9280e8240c9556acfb54efc901bd2b4c 280 Gene3D G3DSA:3.40.50.620 1 268 8.8E-89 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_1480 9280e8240c9556acfb54efc901bd2b4c 280 SMART SM00893 22 218 4.3E-60 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFE_1892 743b81bf518155dd5cb7c5dae1c3173f 261 PIRSF PIRSF028756 1 260 2.4E-109 T 12-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 AFE_1892 743b81bf518155dd5cb7c5dae1c3173f 261 SUPERFAMILY SSF52540 41 230 4.9E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1892 743b81bf518155dd5cb7c5dae1c3173f 261 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 11 235 2.5E-107 T 12-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 AFE_1892 743b81bf518155dd5cb7c5dae1c3173f 261 Gene3D G3DSA:3.40.50.300 1 253 3.8E-92 T 12-10-2018 AFE_1892 743b81bf518155dd5cb7c5dae1c3173f 261 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 11 235 1.3E-98 T 12-10-2018 IPR022488 Polyphosphate kinase-2-related AFE_2267 9fff38a558c89a81ff78782067e60a2f 523 Gene3D G3DSA:3.40.720.10 36 239 7.7E-29 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_2267 9fff38a558c89a81ff78782067e60a2f 523 Gene3D G3DSA:3.40.720.10 377 523 1.8E-39 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_2267 9fff38a558c89a81ff78782067e60a2f 523 Pfam PF04185 Phosphoesterase family 45 495 1.3E-78 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 AFE_2267 9fff38a558c89a81ff78782067e60a2f 523 SUPERFAMILY SSF53649 350 512 4.25E-8 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFE_0182 6c198e9cf4170e9939bdcc80a33fed1f 298 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 23 105 1.7E-24 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFE_0182 6c198e9cf4170e9939bdcc80a33fed1f 298 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 18 289 32.377 T 12-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFE_0182 6c198e9cf4170e9939bdcc80a33fed1f 298 Gene3D G3DSA:3.40.50.10860 21 276 3.9E-80 T 12-10-2018 AFE_0182 6c198e9cf4170e9939bdcc80a33fed1f 298 Gene3D G3DSA:3.40.50.720 117 257 3.9E-80 T 12-10-2018 AFE_0182 6c198e9cf4170e9939bdcc80a33fed1f 298 SUPERFAMILY SSF53223 13 117 2.94E-30 T 12-10-2018 AFE_0182 6c198e9cf4170e9939bdcc80a33fed1f 298 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 133 192 1.1E-6 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AFE_0182 6c198e9cf4170e9939bdcc80a33fed1f 298 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 20 291 1.9E-63 T 12-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFE_0182 6c198e9cf4170e9939bdcc80a33fed1f 298 SUPERFAMILY SSF51735 118 291 1.97E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0220 d14a2a6c3a49d58980675939edf47e1e 580 Gene3D G3DSA:3.40.50.12780 317 450 9.4E-42 T 12-10-2018 AFE_0220 d14a2a6c3a49d58980675939edf47e1e 580 Pfam PF00501 AMP-binding enzyme 18 456 7.4E-92 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFE_0220 d14a2a6c3a49d58980675939edf47e1e 580 SUPERFAMILY SSF56801 10 575 2.09E-118 T 12-10-2018 AFE_0220 d14a2a6c3a49d58980675939edf47e1e 580 Gene3D G3DSA:3.40.50.12780 6 316 1.3E-51 T 12-10-2018 AFE_0220 d14a2a6c3a49d58980675939edf47e1e 580 ProSitePatterns PS00455 Putative AMP-binding domain signature. 184 195 - T 12-10-2018 IPR020845 AMP-binding, conserved site AFE_0220 d14a2a6c3a49d58980675939edf47e1e 580 Gene3D G3DSA:3.30.300.30 453 573 1.0E-7 T 12-10-2018 AFE_2127 0375f8c863e46709399f9b1fe83b51d3 149 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 96 118 3.0E-33 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFE_2127 0375f8c863e46709399f9b1fe83b51d3 149 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 122 140 3.0E-33 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFE_2127 0375f8c863e46709399f9b1fe83b51d3 149 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 10 27 3.0E-33 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFE_2127 0375f8c863e46709399f9b1fe83b51d3 149 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 72 92 3.0E-33 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFE_2127 0375f8c863e46709399f9b1fe83b51d3 149 SUPERFAMILY SSF54611 7 145 2.62E-46 T 12-10-2018 IPR035958 SecB-like superfamily AFE_2127 0375f8c863e46709399f9b1fe83b51d3 149 Pfam PF02556 Preprotein translocase subunit SecB 3 143 4.1E-52 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFE_2127 0375f8c863e46709399f9b1fe83b51d3 149 Gene3D G3DSA:3.10.420.10 1 149 1.1E-54 T 12-10-2018 IPR035958 SecB-like superfamily AFE_2127 0375f8c863e46709399f9b1fe83b51d3 149 Hamap MF_00821 Protein-export protein SecB [secB]. 1 144 30.969 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFE_2127 0375f8c863e46709399f9b1fe83b51d3 149 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 3 141 1.3E-50 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 Gene3D G3DSA:3.40.50.300 131 309 6.2E-47 T 12-10-2018 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 SUPERFAMILY SSF46689 351 451 3.49E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 Gene3D G3DSA:3.40.50.2300 7 125 6.1E-37 T 12-10-2018 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 Pfam PF00072 Response regulator receiver domain 8 113 2.6E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 PRINTS PR00819 CbxX/CfqX superfamily signature 221 240 4.8E-5 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 PRINTS PR00819 CbxX/CfqX superfamily signature 354 366 4.8E-5 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 PRINTS PR00819 CbxX/CfqX superfamily signature 166 181 4.8E-5 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 Gene3D G3DSA:1.10.8.60 310 385 1.5E-21 T 12-10-2018 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 351 360 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 SMART SM00448 6 117 1.9E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 SUPERFAMILY SSF52172 5 188 3.27E-42 T 12-10-2018 IPR011006 CheY-like superfamily AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 SUPERFAMILY SSF52540 145 382 2.3E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 Pfam PF02954 Bacterial regulatory protein, Fis family 409 447 5.8E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 Pfam PF00158 Sigma-54 interaction domain 145 304 2.2E-44 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 224 239 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFE_0024 80473bfa74cae206a4239b6cc617b66c 468 Gene3D G3DSA:1.10.10.60 402 455 3.5E-15 T 12-10-2018 AFE_1675 8688878ca7f9c7b9dc756642783ab165 251 Pfam PF13500 AAA domain 6 182 2.4E-38 T 12-10-2018 AFE_1675 8688878ca7f9c7b9dc756642783ab165 251 SUPERFAMILY SSF52540 6 210 2.59E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1675 8688878ca7f9c7b9dc756642783ab165 251 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 8 178 2.9E-44 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFE_1675 8688878ca7f9c7b9dc756642783ab165 251 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 4 193 25.915 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFE_1675 8688878ca7f9c7b9dc756642783ab165 251 Gene3D G3DSA:3.40.50.300 5 218 9.7E-61 T 12-10-2018 AFE_0434 c25306b54820143e0630813abf3d7fec 390 SUPERFAMILY SSF51649 109 388 8.51E-68 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_0434 c25306b54820143e0630813abf3d7fec 390 SUPERFAMILY SSF54966 4 106 3.01E-19 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_0434 c25306b54820143e0630813abf3d7fec 390 Gene3D G3DSA:3.20.20.110 109 390 2.9E-75 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_0434 c25306b54820143e0630813abf3d7fec 390 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 304 387 2.4E-11 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_0434 c25306b54820143e0630813abf3d7fec 390 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 113 265 4.7E-21 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_0434 c25306b54820143e0630813abf3d7fec 390 Gene3D G3DSA:3.30.70.150 2 107 9.4E-19 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFE_2274 a771bc1d20d2dd756ca2c1b55da4a399 962 Gene3D G3DSA:2.130.10.10 332 450 1.0E-12 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_2274 a771bc1d20d2dd756ca2c1b55da4a399 962 Gene3D G3DSA:2.130.10.10 173 331 7.0E-15 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_2274 a771bc1d20d2dd756ca2c1b55da4a399 962 Pfam PF04185 Phosphoesterase family 546 822 1.9E-7 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 AFE_2274 a771bc1d20d2dd756ca2c1b55da4a399 962 Gene3D G3DSA:3.40.720.10 736 857 2.3E-10 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_2274 a771bc1d20d2dd756ca2c1b55da4a399 962 SUPERFAMILY SSF75011 172 444 1.44E-27 T 12-10-2018 AFE_0035 b23ed9785f99a2307499a81d0935dfd1 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.357 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0035 b23ed9785f99a2307499a81d0935dfd1 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 2.0E-11 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0035 b23ed9785f99a2307499a81d0935dfd1 44 Pfam PF00468 Ribosomal protein L34 1 43 2.9E-23 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0035 b23ed9785f99a2307499a81d0935dfd1 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 42 2.8E-24 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0035 b23ed9785f99a2307499a81d0935dfd1 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 12-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_1595 9f0b5d127fbfcc196de32b0a6e96ce6a 252 Gene3D G3DSA:3.30.450.40 43 221 1.2E-7 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_1595 9f0b5d127fbfcc196de32b0a6e96ce6a 252 SUPERFAMILY SSF55781 71 216 3.68E-8 T 12-10-2018 AFE_2798 715edd4a7c2dfc15464d1e2ff17ac4ad 174 Gene3D G3DSA:1.10.10.10 90 173 7.4E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2798 715edd4a7c2dfc15464d1e2ff17ac4ad 174 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 92 171 1.1E-31 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFE_2798 715edd4a7c2dfc15464d1e2ff17ac4ad 174 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 141 147 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFE_2798 715edd4a7c2dfc15464d1e2ff17ac4ad 174 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 91 170 6.4E-35 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFE_2798 715edd4a7c2dfc15464d1e2ff17ac4ad 174 SUPERFAMILY SSF53155 10 95 1.26E-6 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFE_2798 715edd4a7c2dfc15464d1e2ff17ac4ad 174 SUPERFAMILY SSF46767 90 171 2.22E-30 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 AFE_2863 329760f74a66b23159a3966ac89054e5 371 Pfam PF12698 ABC-2 family transporter protein 24 363 6.1E-43 T 12-10-2018 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 Gene3D G3DSA:1.10.238.260 283 397 6.0E-37 T 12-10-2018 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 5 512 43.367 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 SUPERFAMILY SSF110921 399 502 3.92E-26 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 Gene3D G3DSA:3.30.160.270 398 504 3.0E-12 T 12-10-2018 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 Pfam PF08502 LeuA allosteric (dimerisation) domain 372 503 5.1E-38 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 15 31 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 SMART SM00917 372 503 2.7E-43 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 SUPERFAMILY SSF51569 5 294 4.58E-100 T 12-10-2018 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 202 215 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 Gene3D G3DSA:3.20.20.70 4 279 1.8E-109 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 Pfam PF00682 HMGL-like 8 276 6.5E-99 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFE_2596 fedc265d6d7e80105aae6b9b2a980f8e 513 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 8 500 9.7E-219 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFE_1373 08cec03f29fb8fd64782ee994219e30e 252 SMART SM00382 98 252 1.6E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1373 08cec03f29fb8fd64782ee994219e30e 252 PIRSF PIRSF003073 1 250 4.1E-70 T 12-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein AFE_1373 08cec03f29fb8fd64782ee994219e30e 252 SUPERFAMILY SSF52540 65 237 1.53E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1373 08cec03f29fb8fd64782ee994219e30e 252 Gene3D G3DSA:3.40.50.300 62 246 4.3E-43 T 12-10-2018 AFE_1373 08cec03f29fb8fd64782ee994219e30e 252 Pfam PF01695 IstB-like ATP binding protein 53 229 1.5E-63 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 AFE_1373 08cec03f29fb8fd64782ee994219e30e 252 Pfam PF08483 IstB-like ATP binding N-terminal 24 52 1.6E-11 T 12-10-2018 IPR013690 IstB-like ATP binding N-terminal AFE_3043 42f25716c1d27c22db5d22d8469a83ff 199 Gene3D G3DSA:3.30.230.40 1 91 2.0E-37 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 AFE_3043 42f25716c1d27c22db5d22d8469a83ff 199 SUPERFAMILY SSF54211 4 87 2.78E-32 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_3043 42f25716c1d27c22db5d22d8469a83ff 199 Gene3D G3DSA:3.30.230.40 92 198 2.0E-40 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 AFE_3043 42f25716c1d27c22db5d22d8469a83ff 199 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFE_3043 42f25716c1d27c22db5d22d8469a83ff 199 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 33 176 8.1E-63 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFE_3043 42f25716c1d27c22db5d22d8469a83ff 199 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 63 76 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFE_3043 42f25716c1d27c22db5d22d8469a83ff 199 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 4 197 42.691 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFE_3043 42f25716c1d27c22db5d22d8469a83ff 199 SUPERFAMILY SSF54211 90 180 6.32E-35 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_0929 aa21ced841f653c308d17f5f41cbe309 162 Pfam PF04608 Phosphatidylglycerophosphatase A 8 156 6.3E-48 T 12-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 AFE_0929 aa21ced841f653c308d17f5f41cbe309 162 PIRSF PIRSF006162 1 162 6.5E-46 T 12-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFE_0929 aa21ced841f653c308d17f5f41cbe309 162 SUPERFAMILY SSF101307 4 157 1.96E-37 T 12-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 AFE_1534 7c80e386a008542dc3fa36a490f4856b 263 Gene3D G3DSA:1.25.10.10 6 246 7.0E-73 T 12-10-2018 IPR011989 Armadillo-like helical AFE_1534 7c80e386a008542dc3fa36a490f4856b 263 SUPERFAMILY SSF48371 29 220 1.89E-41 T 12-10-2018 IPR016024 Armadillo-type fold AFE_1534 7c80e386a008542dc3fa36a490f4856b 263 Pfam PF05484 LRV protein FeS4 cluster 7 57 9.2E-20 T 12-10-2018 IPR008665 LRV FeS4 cluster AFE_3117 8e42ea68ad8320f4d6a341c18b860755 76 Gene3D G3DSA:3.30.110.40 1 76 7.6E-25 T 12-10-2018 IPR036868 TusA-like domain superfamily AFE_3117 8e42ea68ad8320f4d6a341c18b860755 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 12-10-2018 IPR001455 TusA-like domain AFE_3117 8e42ea68ad8320f4d6a341c18b860755 76 SUPERFAMILY SSF64307 5 74 4.84E-20 T 12-10-2018 IPR036868 TusA-like domain superfamily AFE_3117 8e42ea68ad8320f4d6a341c18b860755 76 Pfam PF01206 Sulfurtransferase TusA 5 74 5.3E-19 T 12-10-2018 IPR001455 TusA-like domain AFE_2600 8e42ea68ad8320f4d6a341c18b860755 76 Gene3D G3DSA:3.30.110.40 1 76 7.6E-25 T 12-10-2018 IPR036868 TusA-like domain superfamily AFE_2600 8e42ea68ad8320f4d6a341c18b860755 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 12-10-2018 IPR001455 TusA-like domain AFE_2600 8e42ea68ad8320f4d6a341c18b860755 76 SUPERFAMILY SSF64307 5 74 4.84E-20 T 12-10-2018 IPR036868 TusA-like domain superfamily AFE_2600 8e42ea68ad8320f4d6a341c18b860755 76 Pfam PF01206 Sulfurtransferase TusA 5 74 5.3E-19 T 12-10-2018 IPR001455 TusA-like domain AFE_0736 1e7ac87814acab107cdb9c681dc88803 182 Pfam PF04351 Pilus assembly protein, PilP 29 178 8.8E-35 T 12-10-2018 IPR007446 Pilus assembly protein PilP AFE_0736 1e7ac87814acab107cdb9c681dc88803 182 Gene3D G3DSA:2.30.30.830 82 179 7.6E-16 T 12-10-2018 AFE_3257 3264925b1f9ab6c9f5ef3c23d47cf5b1 241 Gene3D G3DSA:2.40.240.20 1 70 5.8E-14 T 12-10-2018 AFE_3257 3264925b1f9ab6c9f5ef3c23d47cf5b1 241 Gene3D G3DSA:3.40.1280.10 75 241 3.0E-49 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFE_3257 3264925b1f9ab6c9f5ef3c23d47cf5b1 241 SUPERFAMILY SSF75217 76 240 1.15E-42 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFE_3257 3264925b1f9ab6c9f5ef3c23d47cf5b1 241 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 13 241 1.3E-43 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 AFE_3257 3264925b1f9ab6c9f5ef3c23d47cf5b1 241 Pfam PF04452 RNA methyltransferase 23 236 1.0E-58 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 AFE_3257 3264925b1f9ab6c9f5ef3c23d47cf5b1 241 PIRSF PIRSF015601 2 241 5.4E-47 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 AFE_3257 3264925b1f9ab6c9f5ef3c23d47cf5b1 241 SUPERFAMILY SSF88697 5 70 1.64E-11 T 12-10-2018 IPR015947 PUA-like superfamily AFE_1531 fc6f8b06096f84b0d8bc5680de38af60 111 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 4 108 1.9E-27 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 AFE_1531 fc6f8b06096f84b0d8bc5680de38af60 111 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 104 1.1E-20 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFE_1531 fc6f8b06096f84b0d8bc5680de38af60 111 SUPERFAMILY SSF89360 1 97 6.28E-24 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFE_1531 fc6f8b06096f84b0d8bc5680de38af60 111 Gene3D G3DSA:2.60.300.12 2 110 2.5E-28 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFE_3199 5696488516599908a8b34b7f3adb9e67 278 Pfam PF08722 TnsA endonuclease N terminal 75 168 6.8E-27 T 12-10-2018 IPR014833 TnsA endonuclease, N-terminal AFE_3199 5696488516599908a8b34b7f3adb9e67 278 SUPERFAMILY SSF52980 9 171 2.41E-66 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFE_3199 5696488516599908a8b34b7f3adb9e67 278 Gene3D G3DSA:3.40.1350.10 8 171 6.3E-70 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFE_3199 5696488516599908a8b34b7f3adb9e67 278 Pfam PF08721 TnsA endonuclease C terminal 170 253 2.4E-21 T 12-10-2018 IPR014832 TnsA endonuclease C-terminal AFE_0297 e5b139e372c93106456e4e00b9b1f821 366 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 149 362 9.6E-52 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 AFE_0297 e5b139e372c93106456e4e00b9b1f821 366 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 359 8.9E-113 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 AFE_0297 e5b139e372c93106456e4e00b9b1f821 366 Pfam PF01872 RibD C-terminal domain 150 358 3.8E-47 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFE_0297 e5b139e372c93106456e4e00b9b1f821 366 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 103 1.0E-19 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AFE_0297 e5b139e372c93106456e4e00b9b1f821 366 Gene3D G3DSA:3.40.140.10 2 138 9.6E-44 T 12-10-2018 AFE_0297 e5b139e372c93106456e4e00b9b1f821 366 PIRSF PIRSF006769 1 365 2.6E-122 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 AFE_0297 e5b139e372c93106456e4e00b9b1f821 366 SUPERFAMILY SSF53927 6 148 2.17E-45 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFE_0297 e5b139e372c93106456e4e00b9b1f821 366 SUPERFAMILY SSF53597 147 360 1.81E-58 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFE_0297 e5b139e372c93106456e4e00b9b1f821 366 Gene3D G3DSA:3.40.430.10 139 366 4.6E-68 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFE_0297 e5b139e372c93106456e4e00b9b1f821 366 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 91 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFE_0956 fc8fa59d1220f7ac36722ecb4e7c7f06 291 Gene3D G3DSA:3.60.15.10 48 276 4.4E-45 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_0956 fc8fa59d1220f7ac36722ecb4e7c7f06 291 SMART SM00849 59 217 7.6E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_0956 fc8fa59d1220f7ac36722ecb4e7c7f06 291 SUPERFAMILY SSF56281 48 225 3.08E-32 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_0550 30cea7deac58ba396599e6242505f2ae 408 Pfam PF01548 Transposase 11 157 3.8E-31 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 AFE_0550 30cea7deac58ba396599e6242505f2ae 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 255 338 6.4E-24 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 AFE_2709 30cea7deac58ba396599e6242505f2ae 408 Pfam PF01548 Transposase 11 157 3.8E-31 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 AFE_2709 30cea7deac58ba396599e6242505f2ae 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 255 338 6.4E-24 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 AFE_1110 30cea7deac58ba396599e6242505f2ae 408 Pfam PF01548 Transposase 11 157 3.8E-31 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 AFE_1110 30cea7deac58ba396599e6242505f2ae 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 255 338 6.4E-24 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 AFE_2972 30cea7deac58ba396599e6242505f2ae 408 Pfam PF01548 Transposase 11 157 3.8E-31 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 AFE_2972 30cea7deac58ba396599e6242505f2ae 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 255 338 6.4E-24 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 AFE_1142 30cea7deac58ba396599e6242505f2ae 408 Pfam PF01548 Transposase 11 157 3.8E-31 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 AFE_1142 30cea7deac58ba396599e6242505f2ae 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 255 338 6.4E-24 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 AFE_3263 30cea7deac58ba396599e6242505f2ae 408 Pfam PF01548 Transposase 11 157 3.8E-31 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 AFE_3263 30cea7deac58ba396599e6242505f2ae 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 255 338 6.4E-24 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 AFE_1265 30cea7deac58ba396599e6242505f2ae 408 Pfam PF01548 Transposase 11 157 3.8E-31 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 AFE_1265 30cea7deac58ba396599e6242505f2ae 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 255 338 6.4E-24 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 AFE_2432 30cea7deac58ba396599e6242505f2ae 408 Pfam PF01548 Transposase 11 157 3.8E-31 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 AFE_2432 30cea7deac58ba396599e6242505f2ae 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 255 338 6.4E-24 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 AFE_0732 b85422ff23365cde2042ce8342340b05 266 Pfam PF02511 Thymidylate synthase complementing protein 23 239 1.2E-49 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 AFE_0732 b85422ff23365cde2042ce8342340b05 266 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 28 244 2.3E-40 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 AFE_0732 b85422ff23365cde2042ce8342340b05 266 Gene3D G3DSA:3.30.1360.170 11 252 1.5E-51 T 12-10-2018 AFE_0732 b85422ff23365cde2042ce8342340b05 266 SUPERFAMILY SSF69796 14 248 2.62E-48 T 12-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 AFE_0888 3df8c504adcef2cd0617928bcc82a02e 97 Gene3D G3DSA:3.30.110.70 1 96 1.3E-23 T 12-10-2018 AFE_0888 3df8c504adcef2cd0617928bcc82a02e 97 Pfam PF01906 Putative heavy-metal-binding 1 94 2.6E-27 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 AFE_0888 3df8c504adcef2cd0617928bcc82a02e 97 SUPERFAMILY SSF117782 1 95 1.44E-25 T 12-10-2018 IPR035439 UPF0145 domain superfamily AFE_0728 5f4de302414f886e806ff01e3d923802 354 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFE_0728 5f4de302414f886e806ff01e3d923802 354 SUPERFAMILY SSF51726 5 352 1.92E-119 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFE_0728 5f4de302414f886e806ff01e3d923802 354 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 23 32 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFE_0728 5f4de302414f886e806ff01e3d923802 354 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 349 7.8E-140 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFE_0728 5f4de302414f886e806ff01e3d923802 354 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 10 347 5.3E-133 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFE_0728 5f4de302414f886e806ff01e3d923802 354 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 7 350 50.586 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFE_0728 5f4de302414f886e806ff01e3d923802 354 Gene3D G3DSA:3.20.20.210 1 352 1.0E-153 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFE_1133 e4b09c16ff795273398c085277fb1ab7 159 SUPERFAMILY SSF52499 3 128 1.83E-15 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFE_1133 e4b09c16ff795273398c085277fb1ab7 159 Gene3D G3DSA:3.40.50.850 1 158 2.8E-13 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFE_1133 e4b09c16ff795273398c085277fb1ab7 159 Pfam PF00857 Isochorismatase family 67 135 3.0E-7 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFE_1964 c86dea9a0168012a11690505a9b1b0c7 374 Pfam PF00487 Fatty acid desaturase 61 315 8.1E-26 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 AFE_1808 b3526eb84fc12d8db3b12dcc36199555 307 Gene3D G3DSA:3.40.718.10 6 300 2.0E-94 T 12-10-2018 AFE_1808 b3526eb84fc12d8db3b12dcc36199555 307 SUPERFAMILY SSF53659 11 299 3.0E-61 T 12-10-2018 AFE_1808 b3526eb84fc12d8db3b12dcc36199555 307 Pfam PF01515 Phosphate acetyl/butaryl transferase 83 296 4.4E-41 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFE_1808 b3526eb84fc12d8db3b12dcc36199555 307 PIRSF PIRSF000428 1 302 3.1E-78 T 12-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFE_1589 9ede6e5ae48b3482ccbc58d937b0e1c3 89 Pfam PF04221 RelB antitoxin 8 79 4.9E-21 T 12-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ AFE_1589 9ede6e5ae48b3482ccbc58d937b0e1c3 89 Gene3D G3DSA:1.10.1220.10 6 54 5.5E-17 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFE_1589 9ede6e5ae48b3482ccbc58d937b0e1c3 89 PIRSF PIRSF003108 1 89 4.1E-30 T 12-10-2018 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 AFE_1589 9ede6e5ae48b3482ccbc58d937b0e1c3 89 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 3 85 2.8E-22 T 12-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ AFE_2516 f1c231a246e69abc97a83bfa713348d2 222 SUPERFAMILY SSF53067 108 202 3.75E-16 T 12-10-2018 AFE_2516 f1c231a246e69abc97a83bfa713348d2 222 SUPERFAMILY SSF53067 6 104 2.33E-27 T 12-10-2018 AFE_2516 f1c231a246e69abc97a83bfa713348d2 222 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 6 215 2.0E-54 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 AFE_2516 f1c231a246e69abc97a83bfa713348d2 222 Pfam PF00814 Glycoprotease family 33 124 2.9E-26 T 12-10-2018 IPR000905 Gcp-like domain AFE_2516 f1c231a246e69abc97a83bfa713348d2 222 Gene3D G3DSA:3.30.420.40 7 216 2.2E-61 T 12-10-2018 AFE_2516 f1c231a246e69abc97a83bfa713348d2 222 Gene3D G3DSA:3.30.420.40 97 183 2.2E-61 T 12-10-2018 AFE_1879 21e8ef0a0b712460263a8d479bb90a21 363 Gene3D G3DSA:2.40.420.20 280 355 3.9E-76 T 12-10-2018 AFE_1879 21e8ef0a0b712460263a8d479bb90a21 363 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 357 1.3E-76 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_1879 21e8ef0a0b712460263a8d479bb90a21 363 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 268 2.0E-32 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_1879 21e8ef0a0b712460263a8d479bb90a21 363 Gene3D G3DSA:2.40.30.170 58 279 3.9E-76 T 12-10-2018 AFE_1879 21e8ef0a0b712460263a8d479bb90a21 363 SUPERFAMILY SSF111369 59 273 1.7E-47 T 12-10-2018 AFE_1879 21e8ef0a0b712460263a8d479bb90a21 363 Pfam PF00529 HlyD membrane-fusion protein of T1SS 17 343 3.4E-6 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_1879 21e8ef0a0b712460263a8d479bb90a21 363 Gene3D G3DSA:1.10.287.470 103 162 3.9E-76 T 12-10-2018 AFE_1879 21e8ef0a0b712460263a8d479bb90a21 363 Gene3D G3DSA:2.40.50.100 68 196 3.9E-76 T 12-10-2018 AFE_0660 1a50981c065316c69a5ea3ff62a21afc 412 SMART SM00919 168 405 2.8E-104 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFE_0660 1a50981c065316c69a5ea3ff62a21afc 412 SUPERFAMILY SSF51735 168 411 1.04E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0660 1a50981c065316c69a5ea3ff62a21afc 412 Gene3D G3DSA:3.40.50.10380 3 165 2.6E-66 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 AFE_0660 1a50981c065316c69a5ea3ff62a21afc 412 SMART SM01274 23 156 2.7E-73 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFE_0660 1a50981c065316c69a5ea3ff62a21afc 412 Gene3D G3DSA:3.40.50.720 166 412 2.8E-67 T 12-10-2018 AFE_0660 1a50981c065316c69a5ea3ff62a21afc 412 SUPERFAMILY SSF53223 15 166 4.32E-50 T 12-10-2018 AFE_0660 1a50981c065316c69a5ea3ff62a21afc 412 Pfam PF03949 Malic enzyme, NAD binding domain 170 359 1.7E-19 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFE_0660 1a50981c065316c69a5ea3ff62a21afc 412 Pfam PF00390 Malic enzyme, N-terminal domain 25 155 9.4E-24 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFE_3284 4d4058bbb44009ff25793d7a4028a9c1 221 Gene3D G3DSA:1.20.950.20 69 177 2.2E-6 T 12-10-2018 AFE_3284 4d4058bbb44009ff25793d7a4028a9c1 221 SUPERFAMILY SSF103501 11 212 1.31E-25 T 12-10-2018 IPR036197 NarG-like superfamily AFE_2840 d0cc8ffd934c15515a327da096887b23 672 SUPERFAMILY SSF74650 398 656 3.61E-54 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFE_2840 d0cc8ffd934c15515a327da096887b23 672 Pfam PF03065 Glycosyl hydrolase family 57 9 289 9.5E-38 T 12-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 AFE_2840 d0cc8ffd934c15515a327da096887b23 672 Pfam PF09094 Domain of unknown function (DUF1925) 313 390 5.3E-37 T 12-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain AFE_2840 d0cc8ffd934c15515a327da096887b23 672 Gene3D G3DSA:2.70.98.10 399 516 2.0E-22 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFE_2840 d0cc8ffd934c15515a327da096887b23 672 Gene3D G3DSA:2.70.98.10 517 666 4.8E-11 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFE_2840 d0cc8ffd934c15515a327da096887b23 672 Gene3D G3DSA:3.20.110.20 3 389 4.6E-142 T 12-10-2018 AFE_2840 d0cc8ffd934c15515a327da096887b23 672 SUPERFAMILY SSF88713 7 281 2.72E-57 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFE_2840 d0cc8ffd934c15515a327da096887b23 672 SUPERFAMILY SSF88688 313 390 1.31E-30 T 12-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily AFE_2840 d0cc8ffd934c15515a327da096887b23 672 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 321 392 3.0E-23 T 12-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain AFE_2840 d0cc8ffd934c15515a327da096887b23 672 Pfam PF09095 Domain of unknown function (DUF1926) 405 512 8.1E-26 T 12-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 AFE_2840 d0cc8ffd934c15515a327da096887b23 672 Pfam PF09095 Domain of unknown function (DUF1926) 531 660 2.9E-19 T 12-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 AFE_0705 6d89c72c4ec54c74cf439b5cdaba1a9c 157 Gene3D G3DSA:3.40.50.1450 2 156 4.2E-39 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFE_0705 6d89c72c4ec54c74cf439b5cdaba1a9c 157 PRINTS PR00446 Hydrogen uptake protein signature 56 66 1.0E-11 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_0705 6d89c72c4ec54c74cf439b5cdaba1a9c 157 PRINTS PR00446 Hydrogen uptake protein signature 35 52 1.0E-11 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_0705 6d89c72c4ec54c74cf439b5cdaba1a9c 157 PRINTS PR00446 Hydrogen uptake protein signature 67 83 1.0E-11 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_0705 6d89c72c4ec54c74cf439b5cdaba1a9c 157 PRINTS PR00446 Hydrogen uptake protein signature 2 14 1.0E-11 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_0705 6d89c72c4ec54c74cf439b5cdaba1a9c 157 PRINTS PR00446 Hydrogen uptake protein signature 14 25 1.0E-11 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_0705 6d89c72c4ec54c74cf439b5cdaba1a9c 157 Pfam PF01750 Hydrogenase maturation protease 21 146 3.0E-12 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_0705 6d89c72c4ec54c74cf439b5cdaba1a9c 157 SUPERFAMILY SSF53163 3 152 9.68E-34 T 12-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFE_0705 6d89c72c4ec54c74cf439b5cdaba1a9c 157 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 3 149 1.4E-37 T 12-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFE_0774 61e4d6fdc183a14c26b2beb6ac2223d3 333 Gene3D G3DSA:3.40.50.1580 39 331 5.6E-21 T 12-10-2018 AFE_0774 61e4d6fdc183a14c26b2beb6ac2223d3 333 SUPERFAMILY SSF53167 38 313 6.07E-10 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFE_0774 61e4d6fdc183a14c26b2beb6ac2223d3 333 Pfam PF06516 Purine nucleoside permease (NUP) 38 330 3.8E-48 T 12-10-2018 IPR009486 Purine nucleoside permease GO:0055085 AFE_2505 7ef1c206557c7a83c37b25a8c82c24c2 626 Pfam PF00665 Integrase core domain 230 366 3.5E-17 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFE_2505 7ef1c206557c7a83c37b25a8c82c24c2 626 Pfam PF09299 Mu transposase, C-terminal 452 515 1.0E-8 T 12-10-2018 IPR015378 Transposase-like, Mu, C-terminal AFE_2505 7ef1c206557c7a83c37b25a8c82c24c2 626 SUPERFAMILY SSF53098 223 422 3.92E-24 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_2505 7ef1c206557c7a83c37b25a8c82c24c2 626 Gene3D G3DSA:3.30.420.10 227 432 1.1E-31 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_2505 7ef1c206557c7a83c37b25a8c82c24c2 626 Pfam PF13518 Helix-turn-helix domain 80 134 7.4E-9 T 12-10-2018 AFE_2854 5dcc5fb02aadde4e3a3062a297307625 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 10 170 4.1E-42 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 AFE_2854 5dcc5fb02aadde4e3a3062a297307625 171 Gene3D G3DSA:2.30.30.240 101 171 1.2E-20 T 12-10-2018 AFE_2854 5dcc5fb02aadde4e3a3062a297307625 171 Gene3D G3DSA:2.40.30.60 9 95 3.6E-27 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 AFE_2854 5dcc5fb02aadde4e3a3062a297307625 171 Pfam PF01782 RimM N-terminal domain 13 91 3.4E-20 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 AFE_2854 5dcc5fb02aadde4e3a3062a297307625 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 10 171 21.845 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 AFE_2854 5dcc5fb02aadde4e3a3062a297307625 171 SUPERFAMILY SSF50447 9 95 5.3E-20 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_2854 5dcc5fb02aadde4e3a3062a297307625 171 SUPERFAMILY SSF50346 101 170 4.51E-16 T 12-10-2018 IPR011033 PRC-barrel-like superfamily AFE_2854 5dcc5fb02aadde4e3a3062a297307625 171 Pfam PF05239 PRC-barrel domain 99 166 6.8E-8 T 12-10-2018 IPR027275 PRC-barrel domain AFE_2942 f8407f138d741a428829208393fd6b35 192 Pfam PF01292 Prokaryotic cytochrome b561 8 182 1.3E-13 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFE_2942 f8407f138d741a428829208393fd6b35 192 SUPERFAMILY SSF81342 5 188 7.22E-9 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFE_2626 21ed8a4366fe52a8b868e51aea5ada20 163 Gene3D G3DSA:3.40.30.10 74 162 3.7E-29 T 12-10-2018 AFE_2626 21ed8a4366fe52a8b868e51aea5ada20 163 SUPERFAMILY SSF52833 3 158 3.24E-54 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_2626 21ed8a4366fe52a8b868e51aea5ada20 163 Gene3D G3DSA:1.10.10.1590 2 73 3.3E-22 T 12-10-2018 AFE_2626 21ed8a4366fe52a8b868e51aea5ada20 163 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 10 155 1.8E-58 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2626 21ed8a4366fe52a8b868e51aea5ada20 163 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 113 131 - T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2626 21ed8a4366fe52a8b868e51aea5ada20 163 PIRSF PIRSF000216 1 163 4.6E-61 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2626 21ed8a4366fe52a8b868e51aea5ada20 163 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 14 155 2.7E-54 T 12-10-2018 AFE_0484 1f5be455d2e50f0c32807c91005d5c03 736 Pfam PF03772 Competence protein 237 505 3.3E-53 T 12-10-2018 IPR004477 ComEC/Rec2-related protein AFE_0484 1f5be455d2e50f0c32807c91005d5c03 736 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 258 433 2.2E-22 T 12-10-2018 IPR004477 ComEC/Rec2-related protein AFE_1856 ea4f37cef81394fc048cc1abe04599b0 502 Pfam PF05199 GMC oxidoreductase 381 487 1.4E-22 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 AFE_1856 ea4f37cef81394fc048cc1abe04599b0 502 Gene3D G3DSA:3.50.50.60 1 139 5.9E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1856 ea4f37cef81394fc048cc1abe04599b0 502 Gene3D G3DSA:3.50.50.60 408 499 2.5E-18 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1856 ea4f37cef81394fc048cc1abe04599b0 502 Gene3D G3DSA:3.50.50.60 197 308 6.3E-7 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1856 ea4f37cef81394fc048cc1abe04599b0 502 SUPERFAMILY SSF51905 1 495 7.92E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1856 ea4f37cef81394fc048cc1abe04599b0 502 Pfam PF00732 GMC oxidoreductase 46 293 3.2E-8 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 AFE_0167 aca76f6423df8f499a569adf30e755f1 267 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 7 261 53.473 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AFE_0167 aca76f6423df8f499a569adf30e755f1 267 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 39 66 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 AFE_0167 aca76f6423df8f499a569adf30e755f1 267 SUPERFAMILY SSF53335 7 261 1.98E-71 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0167 aca76f6423df8f499a569adf30e755f1 267 Gene3D G3DSA:1.10.8.100 202 263 9.5E-18 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 AFE_0167 aca76f6423df8f499a569adf30e755f1 267 Pfam PF00398 Ribosomal RNA adenine dimethylase 9 258 6.5E-58 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm AFE_0167 aca76f6423df8f499a569adf30e755f1 267 Gene3D G3DSA:3.40.50.150 2 196 4.5E-65 T 12-10-2018 AFE_0167 aca76f6423df8f499a569adf30e755f1 267 SMART SM00650 23 194 1.0E-71 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 AFE_0167 aca76f6423df8f499a569adf30e755f1 267 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 8 259 1.2E-76 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AFE_1503 c2be81b3e629b3f5171cdb240df7495a 538 Gene3D G3DSA:3.40.109.10 275 512 1.8E-39 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFE_1503 c2be81b3e629b3f5171cdb240df7495a 538 Gene3D G3DSA:3.40.109.10 33 246 3.8E-56 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFE_1503 c2be81b3e629b3f5171cdb240df7495a 538 SUPERFAMILY SSF55469 102 221 3.14E-7 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFE_1503 c2be81b3e629b3f5171cdb240df7495a 538 Pfam PF00881 Nitroreductase family 314 512 2.2E-5 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFE_1503 c2be81b3e629b3f5171cdb240df7495a 538 SUPERFAMILY SSF55469 312 525 1.5E-13 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFE_0686 64cbaa10eb8ae50b63ba760a267ca1f1 561 Pfam PF01420 Type I restriction modification DNA specificity domain 389 537 2.6E-6 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFE_0686 64cbaa10eb8ae50b63ba760a267ca1f1 561 SUPERFAMILY SSF116734 86 326 9.65E-21 T 12-10-2018 AFE_0686 64cbaa10eb8ae50b63ba760a267ca1f1 561 Gene3D G3DSA:3.90.220.20 347 560 5.3E-33 T 12-10-2018 AFE_0686 64cbaa10eb8ae50b63ba760a267ca1f1 561 Gene3D G3DSA:3.90.220.20 182 271 1.6E-5 T 12-10-2018 AFE_0686 64cbaa10eb8ae50b63ba760a267ca1f1 561 SUPERFAMILY SSF116734 353 546 1.96E-33 T 12-10-2018 AFE_2085 d3b0e5abf8a6367fe37430d2581287ec 213 SUPERFAMILY SSF53474 7 212 4.05E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_2085 d3b0e5abf8a6367fe37430d2581287ec 213 Pfam PF01738 Dienelactone hydrolase family 85 203 2.4E-5 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 AFE_2085 d3b0e5abf8a6367fe37430d2581287ec 213 Gene3D G3DSA:3.40.50.1820 2 212 2.0E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_1925 1fec5793160b2bda25ca032d361bf8ef 151 Pfam PF00571 CBS domain 5 57 2.7E-12 T 12-10-2018 IPR000644 CBS domain AFE_1925 1fec5793160b2bda25ca032d361bf8ef 151 Pfam PF00571 CBS domain 94 149 4.0E-13 T 12-10-2018 IPR000644 CBS domain AFE_1925 1fec5793160b2bda25ca032d361bf8ef 151 Gene3D G3DSA:3.10.580.10 1 150 1.4E-33 T 12-10-2018 AFE_1925 1fec5793160b2bda25ca032d361bf8ef 151 SUPERFAMILY SSF54631 3 148 1.77E-33 T 12-10-2018 AFE_1925 1fec5793160b2bda25ca032d361bf8ef 151 SMART SM00116 101 149 7.2E-8 T 12-10-2018 IPR000644 CBS domain AFE_1925 1fec5793160b2bda25ca032d361bf8ef 151 SMART SM00116 11 59 6.5E-7 T 12-10-2018 IPR000644 CBS domain AFE_2037 ce557eacbb21b9bd66ce9ceffdcb367c 449 SUPERFAMILY SSF56954 3 442 1.12E-49 T 12-10-2018 AFE_2037 ce557eacbb21b9bd66ce9ceffdcb367c 449 Gene3D G3DSA:1.20.1600.10 65 446 3.7E-39 T 12-10-2018 AFE_2037 ce557eacbb21b9bd66ce9ceffdcb367c 449 Pfam PF02321 Outer membrane efflux protein 75 242 1.0E-4 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_2037 ce557eacbb21b9bd66ce9ceffdcb367c 449 Pfam PF02321 Outer membrane efflux protein 266 439 4.4E-13 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_2731 bfcd26ed8366b32033818eaefbd4aecb 233 Pfam PF02167 Cytochrome C1 family 35 231 6.7E-18 T 12-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 AFE_2731 bfcd26ed8366b32033818eaefbd4aecb 233 Gene3D G3DSA:1.10.760.10 29 198 1.9E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_2731 bfcd26ed8366b32033818eaefbd4aecb 233 SUPERFAMILY SSF46626 31 196 4.94E-43 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_1549 b49707419beccf04d499f3ccdda25d0b 190 SUPERFAMILY SSF50182 109 173 3.27E-11 T 12-10-2018 IPR010920 LSM domain superfamily AFE_1549 b49707419beccf04d499f3ccdda25d0b 190 Pfam PF00924 Mechanosensitive ion channel 63 171 2.7E-15 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFE_1549 b49707419beccf04d499f3ccdda25d0b 190 Gene3D G3DSA:2.30.30.60 124 173 1.6E-6 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily AFE_2157 fa5704904103b427313f53cf318ad0fa 759 Pfam PF00092 von Willebrand factor type A domain 568 725 5.0E-9 T 12-10-2018 IPR002035 von Willebrand factor, type A AFE_2157 fa5704904103b427313f53cf318ad0fa 759 Gene3D G3DSA:3.40.50.410 565 754 7.2E-15 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_2157 fa5704904103b427313f53cf318ad0fa 759 SUPERFAMILY SSF53300 566 752 6.2E-20 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_2157 fa5704904103b427313f53cf318ad0fa 759 SMART SM00327 565 758 2.0E-16 T 12-10-2018 IPR002035 von Willebrand factor, type A AFE_2346 337f5e96a9001485a9ad4b0a882b210a 385 Gene3D G3DSA:3.80.30.20 2 299 2.9E-95 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFE_2346 337f5e96a9001485a9ad4b0a882b210a 385 SMART SM00729 10 230 1.2E-43 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFE_2346 337f5e96a9001485a9ad4b0a882b210a 385 Pfam PF06969 HemN C-terminal domain 312 373 6.5E-15 T 12-10-2018 IPR010723 HemN, C-terminal AFE_2346 337f5e96a9001485a9ad4b0a882b210a 385 Pfam PF04055 Radical SAM superfamily 15 176 2.1E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_2346 337f5e96a9001485a9ad4b0a882b210a 385 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 12 353 6.3E-105 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 AFE_2346 337f5e96a9001485a9ad4b0a882b210a 385 SUPERFAMILY SSF102114 8 384 2.62E-106 T 12-10-2018 AFE_0187 aa591f19e50c8eddf8d478c97c19994e 204 Pfam PF01121 Dephospho-CoA kinase 5 184 7.5E-57 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFE_0187 aa591f19e50c8eddf8d478c97c19994e 204 SUPERFAMILY SSF52540 1 190 8.6E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0187 aa591f19e50c8eddf8d478c97c19994e 204 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 200 26.314 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFE_0187 aa591f19e50c8eddf8d478c97c19994e 204 Gene3D G3DSA:3.40.50.300 1 201 3.4E-62 T 12-10-2018 AFE_0187 aa591f19e50c8eddf8d478c97c19994e 204 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 5 190 4.6E-53 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFE_1418 03dcae82de4d73c40277a661a81a74f0 90 SUPERFAMILY SSF47598 2 79 1.13E-20 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFE_1418 03dcae82de4d73c40277a661a81a74f0 90 Gene3D G3DSA:1.20.5.780 1 83 3.5E-12 T 12-10-2018 AFE_1418 03dcae82de4d73c40277a661a81a74f0 90 Pfam PF08681 Protein of unknown function (DUF1778) 6 80 2.9E-25 T 12-10-2018 IPR014795 Vibrio phage ICP1, Orf50 AFE_2582 dc048680440e999352f38a91eb3f874b 179 Pfam PF13242 HAD-hyrolase-like 100 170 1.1E-12 T 12-10-2018 AFE_2582 dc048680440e999352f38a91eb3f874b 179 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 3 145 3.0E-43 T 12-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 AFE_2582 dc048680440e999352f38a91eb3f874b 179 PIRSF PIRSF004682 1 177 5.1E-55 T 12-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 AFE_2582 dc048680440e999352f38a91eb3f874b 179 Gene3D G3DSA:3.40.50.1000 3 177 4.1E-53 T 12-10-2018 IPR023214 HAD superfamily AFE_2582 dc048680440e999352f38a91eb3f874b 179 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 146 1.9E-32 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 AFE_2582 dc048680440e999352f38a91eb3f874b 179 SUPERFAMILY SSF56784 3 175 1.76E-45 T 12-10-2018 IPR036412 HAD-like superfamily AFE_2434 50ab1fe1652e864eb12a2c4036ebcbe0 433 Gene3D G3DSA:1.20.1600.10 37 432 5.1E-56 T 12-10-2018 AFE_2434 50ab1fe1652e864eb12a2c4036ebcbe0 433 SUPERFAMILY SSF56954 26 426 2.35E-60 T 12-10-2018 AFE_2434 50ab1fe1652e864eb12a2c4036ebcbe0 433 Pfam PF02321 Outer membrane efflux protein 45 226 3.6E-12 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_2434 50ab1fe1652e864eb12a2c4036ebcbe0 433 Pfam PF02321 Outer membrane efflux protein 254 426 4.5E-26 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_0814 5f1f07553cc6a45d9f3f1b4ddcf9f6ed 461 Gene3D G3DSA:1.10.3080.10 7 445 2.7E-95 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 AFE_0814 5f1f07553cc6a45d9f3f1b4ddcf9f6ed 461 SUPERFAMILY SSF81340 20 449 7.46E-88 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 AFE_0814 5f1f07553cc6a45d9f3f1b4ddcf9f6ed 461 Pfam PF00654 Voltage gated chloride channel 79 427 4.4E-78 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0814 5f1f07553cc6a45d9f3f1b4ddcf9f6ed 461 PRINTS PR00762 Chloride channel signature 173 192 1.0E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0814 5f1f07553cc6a45d9f3f1b4ddcf9f6ed 461 PRINTS PR00762 Chloride channel signature 378 394 1.0E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0814 5f1f07553cc6a45d9f3f1b4ddcf9f6ed 461 PRINTS PR00762 Chloride channel signature 396 415 1.0E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0814 5f1f07553cc6a45d9f3f1b4ddcf9f6ed 461 PRINTS PR00762 Chloride channel signature 435 449 1.0E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0814 5f1f07553cc6a45d9f3f1b4ddcf9f6ed 461 PRINTS PR00762 Chloride channel signature 93 110 1.0E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_0814 5f1f07553cc6a45d9f3f1b4ddcf9f6ed 461 PRINTS PR00762 Chloride channel signature 344 364 1.0E-21 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AFE_1848 6038334cc7abc790e2d4356b470b24f8 322 SMART SM00478 135 294 3.0E-10 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFE_1848 6038334cc7abc790e2d4356b470b24f8 322 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 132 284 5.2E-10 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFE_1848 6038334cc7abc790e2d4356b470b24f8 322 ProSitePatterns PS00516 Alkylbase DNA glycosidases alkA family signature. 229 253 - T 12-10-2018 IPR000035 Alkylbase DNA glycosidase, conserved site GO:0003905|GO:0006281 AFE_1848 6038334cc7abc790e2d4356b470b24f8 322 Gene3D G3DSA:1.10.340.30 123 245 1.9E-41 T 12-10-2018 AFE_1848 6038334cc7abc790e2d4356b470b24f8 322 Gene3D G3DSA:1.10.1670.40 103 289 1.9E-41 T 12-10-2018 AFE_1848 6038334cc7abc790e2d4356b470b24f8 322 SUPERFAMILY SSF48150 114 295 6.8E-37 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 SUPERFAMILY SSF102886 4 295 7.59E-131 T 12-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 PIRSF PIRSF000166 1 296 1.3E-123 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 Gene3D G3DSA:3.40.1500.10 1 296 2.0E-133 T 12-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 161 185 - T 12-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 PRINTS PR00073 Coprogen oxidase signature 157 186 2.0E-84 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 PRINTS PR00073 Coprogen oxidase signature 31 47 2.0E-84 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 PRINTS PR00073 Coprogen oxidase signature 48 69 2.0E-84 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 PRINTS PR00073 Coprogen oxidase signature 256 282 2.0E-84 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 PRINTS PR00073 Coprogen oxidase signature 120 142 2.0E-84 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 PRINTS PR00073 Coprogen oxidase signature 90 114 2.0E-84 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 PRINTS PR00073 Coprogen oxidase signature 228 255 2.0E-84 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 Pfam PF01218 Coproporphyrinogen III oxidase 9 295 6.1E-131 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_2263 91f6cbcea3a5d436937c4b0fe808cdd5 296 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 3 271 52.381 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFE_0650 de028c30ca25bd7b40c807e95a50e3c3 167 Gene3D G3DSA:2.60.40.1820 30 162 7.9E-14 T 12-10-2018 AFE_0650 de028c30ca25bd7b40c807e95a50e3c3 167 SMART SM00769 39 157 5.3E-10 T 12-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 AFE_0650 de028c30ca25bd7b40c807e95a50e3c3 167 Pfam PF03168 Late embryogenesis abundant protein 60 152 1.9E-13 T 12-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup AFE_0650 de028c30ca25bd7b40c807e95a50e3c3 167 SUPERFAMILY SSF117070 18 159 2.75E-26 T 12-10-2018 AFE_2467 d1391ee89b2b76e1203bd5d4cfdd9e29 109 SUPERFAMILY SSF55729 8 97 1.44E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_2467 d1391ee89b2b76e1203bd5d4cfdd9e29 109 Pfam PF00583 Acetyltransferase (GNAT) family 9 80 1.6E-11 T 12-10-2018 IPR000182 GNAT domain AFE_2467 d1391ee89b2b76e1203bd5d4cfdd9e29 109 Gene3D G3DSA:3.40.630.30 6 109 2.3E-22 T 12-10-2018 AFE_2927 c762787feaecc42fcec8c0fb1ddb24a3 105 Pfam PF02641 Uncharacterized ACR, COG1993 6 98 4.2E-25 T 12-10-2018 IPR003793 Domain of unknown function DUF190 AFE_2927 c762787feaecc42fcec8c0fb1ddb24a3 105 Gene3D G3DSA:3.30.70.120 1 103 2.5E-27 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFE_2927 c762787feaecc42fcec8c0fb1ddb24a3 105 SUPERFAMILY SSF54913 5 101 5.78E-25 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AFE_3241 027761e4855cb5b18da4a4222ce15ebf 141 Pfam PF02566 OsmC-like protein 36 131 8.1E-17 T 12-10-2018 IPR003718 OsmC/Ohr family AFE_3241 027761e4855cb5b18da4a4222ce15ebf 141 Gene3D G3DSA:3.30.300.20 4 140 5.0E-35 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFE_3241 027761e4855cb5b18da4a4222ce15ebf 141 SUPERFAMILY SSF82784 3 138 1.83E-36 T 12-10-2018 IPR036102 OsmC/Ohr superfamily AFE_1341 f86b87accbcbe519ebd8614f57f9c8b1 253 SUPERFAMILY SSF89550 27 230 4.12E-12 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFE_1341 f86b87accbcbe519ebd8614f57f9c8b1 253 Gene3D G3DSA:3.20.20.140 26 252 5.6E-56 T 12-10-2018 AFE_1341 f86b87accbcbe519ebd8614f57f9c8b1 253 PIRSF PIRSF016557 26 250 3.2E-33 T 12-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 AFE_1682 64cb7d3e8eb1d01f775999e2115c749f 147 SUPERFAMILY SSF47240 1 138 5.55E-27 T 12-10-2018 IPR009078 Ferritin-like superfamily AFE_1682 64cb7d3e8eb1d01f775999e2115c749f 147 Pfam PF00210 Ferritin-like domain 11 138 2.4E-18 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AFE_1682 64cb7d3e8eb1d01f775999e2115c749f 147 PRINTS PR00601 Bacterioferritin signature 44 64 5.0E-11 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFE_1682 64cb7d3e8eb1d01f775999e2115c749f 147 PRINTS PR00601 Bacterioferritin signature 86 106 5.0E-11 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFE_1682 64cb7d3e8eb1d01f775999e2115c749f 147 PRINTS PR00601 Bacterioferritin signature 65 85 5.0E-11 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFE_1682 64cb7d3e8eb1d01f775999e2115c749f 147 PRINTS PR00601 Bacterioferritin signature 3 22 5.0E-11 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFE_1682 64cb7d3e8eb1d01f775999e2115c749f 147 PRINTS PR00601 Bacterioferritin signature 23 43 5.0E-11 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 AFE_1682 64cb7d3e8eb1d01f775999e2115c749f 147 Gene3D G3DSA:1.20.1260.10 1 143 5.4E-33 T 12-10-2018 IPR012347 Ferritin-like AFE_3029 8d42d4b572fc99a102489a80b5e2683e 184 PIRSF PIRSF006118 6 180 1.7E-66 T 12-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFE_3029 8d42d4b572fc99a102489a80b5e2683e 184 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 18 170 7.3E-50 T 12-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFE_3029 8d42d4b572fc99a102489a80b5e2683e 184 SUPERFAMILY SSF56784 14 176 2.71E-35 T 12-10-2018 IPR036412 HAD-like superfamily AFE_3029 8d42d4b572fc99a102489a80b5e2683e 184 Gene3D G3DSA:3.40.50.1000 11 180 1.1E-47 T 12-10-2018 IPR023214 HAD superfamily AFE_3292 7b6ad6cf13a3b919d60f6b57cc39ec5c 343 Gene3D G3DSA:3.90.25.10 186 334 9.4E-146 T 12-10-2018 AFE_3292 7b6ad6cf13a3b919d60f6b57cc39ec5c 343 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 336 1.4E-136 T 12-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 AFE_3292 7b6ad6cf13a3b919d60f6b57cc39ec5c 343 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 339 51.087 T 12-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 AFE_3292 7b6ad6cf13a3b919d60f6b57cc39ec5c 343 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 329 1.0E-130 T 12-10-2018 IPR016040 NAD(P)-binding domain AFE_3292 7b6ad6cf13a3b919d60f6b57cc39ec5c 343 Gene3D G3DSA:3.40.50.720 5 320 9.4E-146 T 12-10-2018 AFE_3292 7b6ad6cf13a3b919d60f6b57cc39ec5c 343 SUPERFAMILY SSF51735 3 334 9.92E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1453 bef3a6d602d92a113d35cbe0935eb19a 178 Gene3D G3DSA:3.30.910.20 16 176 3.9E-32 T 12-10-2018 IPR024930 Skp domain superfamily AFE_1453 bef3a6d602d92a113d35cbe0935eb19a 178 SMART SM00935 10 166 4.8E-40 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 AFE_1453 bef3a6d602d92a113d35cbe0935eb19a 178 Pfam PF03938 Outer membrane protein (OmpH-like) 10 165 1.6E-33 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 AFE_1453 bef3a6d602d92a113d35cbe0935eb19a 178 SUPERFAMILY SSF111384 25 165 1.28E-29 T 12-10-2018 AFE_0745 270c0223d71df921030637aac76f9e26 581 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 20 580 1.8E-262 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFE_0745 270c0223d71df921030637aac76f9e26 581 SUPERFAMILY SSF52518 386 579 1.32E-71 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_0745 270c0223d71df921030637aac76f9e26 581 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 445 464 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AFE_0745 270c0223d71df921030637aac76f9e26 581 Gene3D G3DSA:3.40.50.970 13 202 1.2E-72 T 12-10-2018 AFE_0745 270c0223d71df921030637aac76f9e26 581 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 210 342 1.3E-43 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFE_0745 270c0223d71df921030637aac76f9e26 581 Gene3D G3DSA:3.40.50.1220 204 374 5.2E-61 T 12-10-2018 AFE_0745 270c0223d71df921030637aac76f9e26 581 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 21 185 1.5E-58 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFE_0745 270c0223d71df921030637aac76f9e26 581 SUPERFAMILY SSF52518 17 200 4.48E-64 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_0745 270c0223d71df921030637aac76f9e26 581 SUPERFAMILY SSF52467 202 376 3.13E-65 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFE_0745 270c0223d71df921030637aac76f9e26 581 Gene3D G3DSA:3.40.50.970 377 580 4.3E-69 T 12-10-2018 AFE_0745 270c0223d71df921030637aac76f9e26 581 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 408 556 4.1E-52 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFE_0881 5d37bfe9ad8ecb9b84dff3108d5b6441 192 SUPERFAMILY SSF51182 104 186 3.97E-13 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_0881 5d37bfe9ad8ecb9b84dff3108d5b6441 192 Gene3D G3DSA:2.60.120.10 1 191 3.7E-69 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_0881 5d37bfe9ad8ecb9b84dff3108d5b6441 192 SUPERFAMILY SSF51182 3 98 4.98E-26 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_0881 5d37bfe9ad8ecb9b84dff3108d5b6441 192 Pfam PF12973 ChrR Cupin-like domain 105 182 2.2E-7 T 12-10-2018 IPR025979 ChrR-like cupin domain AFE_0881 5d37bfe9ad8ecb9b84dff3108d5b6441 192 Pfam PF12973 ChrR Cupin-like domain 2 78 2.2E-32 T 12-10-2018 IPR025979 ChrR-like cupin domain AFE_0616 40cb74117b2659826e823ae970a058eb 414 Gene3D G3DSA:3.40.50.2000 222 390 1.9E-37 T 12-10-2018 AFE_0616 40cb74117b2659826e823ae970a058eb 414 Gene3D G3DSA:3.40.50.2000 16 221 1.1E-26 T 12-10-2018 AFE_0616 40cb74117b2659826e823ae970a058eb 414 Pfam PF13439 Glycosyltransferase Family 4 19 209 3.1E-19 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_0616 40cb74117b2659826e823ae970a058eb 414 Pfam PF13692 Glycosyl transferases group 1 228 373 7.0E-28 T 12-10-2018 AFE_0616 40cb74117b2659826e823ae970a058eb 414 SUPERFAMILY SSF53756 17 406 8.03E-67 T 12-10-2018 AFE_0357 00cdbeb016f7b2bd4e32b695742979a3 418 SUPERFAMILY SSF102645 192 406 2.88E-59 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFE_0357 00cdbeb016f7b2bd4e32b695742979a3 418 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 12 401 3.6E-122 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 AFE_0357 00cdbeb016f7b2bd4e32b695742979a3 418 SUPERFAMILY SSF52507 12 185 6.67E-58 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFE_0357 00cdbeb016f7b2bd4e32b695742979a3 418 Gene3D G3DSA:3.40.50.1950 8 193 1.5E-56 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFE_0357 00cdbeb016f7b2bd4e32b695742979a3 418 Pfam PF02441 Flavoprotein 15 186 2.0E-42 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFE_0357 00cdbeb016f7b2bd4e32b695742979a3 418 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 194 377 1.2E-55 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFE_0357 00cdbeb016f7b2bd4e32b695742979a3 418 Gene3D G3DSA:3.40.50.10300 194 408 2.5E-57 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFE_0143 03cad071c502846a47b4bd67b307e492 612 SUPERFAMILY SSF53822 286 604 4.5E-51 T 12-10-2018 IPR028082 Periplasmic binding protein-like I AFE_0143 03cad071c502846a47b4bd67b307e492 612 Gene3D G3DSA:3.40.50.2300 389 593 3.2E-45 T 12-10-2018 AFE_0143 03cad071c502846a47b4bd67b307e492 612 Gene3D G3DSA:3.40.50.2300 289 592 3.2E-45 T 12-10-2018 AFE_0143 03cad071c502846a47b4bd67b307e492 612 SUPERFAMILY SSF48452 53 159 2.55E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0143 03cad071c502846a47b4bd67b307e492 612 Pfam PF04348 LppC putative lipoprotein 67 599 1.6E-56 T 12-10-2018 IPR007443 Penicillin-binding protein activator LpoA AFE_0143 03cad071c502846a47b4bd67b307e492 612 Gene3D G3DSA:1.25.40.10 50 177 8.7E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0143 03cad071c502846a47b4bd67b307e492 612 Gene3D G3DSA:1.25.40.650 178 269 1.4E-8 T 12-10-2018 AFE_1689 f8a949ce521f68e5945de7b54906ead5 762 Pfam PF12288 Carboxysome shell peptide mid-region 154 573 1.9E-163 T 12-10-2018 IPR020990 Carboxysome shell protein AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 SUPERFAMILY SSF52943 2 288 1.22E-92 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 4.3E-33 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 4.3E-33 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 PRINTS PR00126 ATP synthase gamma subunit signature 235 254 4.3E-33 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 PRINTS PR00126 ATP synthase gamma subunit signature 266 287 4.3E-33 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 288 3.8E-112 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 288 35.962 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 Gene3D G3DSA:1.10.287.80 6 284 5.9E-106 T 12-10-2018 AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 Gene3D G3DSA:3.40.1380.10 61 207 5.9E-106 T 12-10-2018 AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 274 287 - T 12-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3204 cb3a3aafb51c2ee46dbcaa572b5f86d8 288 Pfam PF00231 ATP synthase 3 287 5.8E-94 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_1439 52ab5816d04ecd08d5586caef99f581b 255 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_1439 52ab5816d04ecd08d5586caef99f581b 255 SUPERFAMILY SSF52540 8 242 1.42E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1439 52ab5816d04ecd08d5586caef99f581b 255 Gene3D G3DSA:3.40.50.300 7 253 3.5E-67 T 12-10-2018 AFE_1439 52ab5816d04ecd08d5586caef99f581b 255 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 9 255 6.2E-120 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 AFE_1439 52ab5816d04ecd08d5586caef99f581b 255 Pfam PF00005 ABC transporter 26 180 2.9E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_1439 52ab5816d04ecd08d5586caef99f581b 255 SMART SM00382 33 243 7.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_3036 a4eae00c90cf39687465c3e1a99cd625 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 208 227 9.5E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_3036 a4eae00c90cf39687465c3e1a99cd625 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 188 207 9.5E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_3036 a4eae00c90cf39687465c3e1a99cd625 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 36 57 9.5E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_3036 a4eae00c90cf39687465c3e1a99cd625 268 Pfam PF01061 ABC-2 type transporter 22 231 6.5E-36 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFE_3036 a4eae00c90cf39687465c3e1a99cd625 268 PIRSF PIRSF006648 6 265 1.3E-26 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_1109 a7c3ad7f71c1cf7d55c5f1b9efa88f85 225 Pfam PF08378 Nuclease-related domain 26 131 1.4E-16 T 12-10-2018 IPR011528 Nuclease-related domain, NERD AFE_3291 7f1fbdddb9c31a00a14315b816d70a64 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 110 138 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_3291 7f1fbdddb9c31a00a14315b816d70a64 294 Gene3D G3DSA:3.40.50.720 5 275 1.7E-84 T 12-10-2018 AFE_3291 7f1fbdddb9c31a00a14315b816d70a64 294 Pfam PF16363 GDP-mannose 4,6 dehydratase 30 284 3.3E-57 T 12-10-2018 IPR016040 NAD(P)-binding domain AFE_3291 7f1fbdddb9c31a00a14315b816d70a64 294 SUPERFAMILY SSF51735 1 291 4.19E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3291 7f1fbdddb9c31a00a14315b816d70a64 294 Gene3D G3DSA:3.90.25.10 159 282 1.7E-84 T 12-10-2018 AFE_0536 4c3f21b29e9bd040fe09dbf262cc3a89 290 Gene3D G3DSA:3.40.50.300 1 289 1.4E-114 T 12-10-2018 AFE_0536 4c3f21b29e9bd040fe09dbf262cc3a89 290 ProSitePatterns PS00567 Phosphoribulokinase signature. 164 177 - T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 AFE_0536 4c3f21b29e9bd040fe09dbf262cc3a89 290 PRINTS PR00478 Phosphoribulokinase family signature 12 29 7.8E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 AFE_0536 4c3f21b29e9bd040fe09dbf262cc3a89 290 PRINTS PR00478 Phosphoribulokinase family signature 126 144 7.8E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 AFE_0536 4c3f21b29e9bd040fe09dbf262cc3a89 290 PRINTS PR00478 Phosphoribulokinase family signature 182 205 7.8E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 AFE_0536 4c3f21b29e9bd040fe09dbf262cc3a89 290 PRINTS PR00478 Phosphoribulokinase family signature 164 181 7.8E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 AFE_0536 4c3f21b29e9bd040fe09dbf262cc3a89 290 SUPERFAMILY SSF52540 3 285 4.39E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0536 4c3f21b29e9bd040fe09dbf262cc3a89 290 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 214 2.0E-71 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 169 182 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 Gene3D G3DSA:3.40.50.300 143 316 2.5E-58 T 12-10-2018 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 Gene3D G3DSA:1.10.10.60 396 449 1.6E-13 T 12-10-2018 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 Gene3D G3DSA:3.40.50.2300 4 141 1.5E-37 T 12-10-2018 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 Pfam PF00158 Sigma-54 interaction domain 146 311 4.7E-66 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 Pfam PF00072 Response regulator receiver domain 8 115 2.8E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 SUPERFAMILY SSF46689 358 447 2.78E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 SMART SM00382 165 308 2.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 Pfam PF02954 Bacterial regulatory protein, Fis family 407 445 6.1E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 SMART SM00448 6 117 3.8E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 Gene3D G3DSA:1.10.8.60 317 391 4.7E-23 T 12-10-2018 AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 SUPERFAMILY SSF52540 145 387 2.52E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0447 a3d8fcc97beb86e0ec666d219f436210 461 SUPERFAMILY SSF52172 8 189 9.39E-42 T 12-10-2018 IPR011006 CheY-like superfamily AFE_0194 d01c49e0fbbbd71e8ed612323f4b1c88 292 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 5 288 4.8E-76 T 12-10-2018 AFE_0194 d01c49e0fbbbd71e8ed612323f4b1c88 292 PIRSF PIRSF000401 3 290 4.4E-72 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AFE_0194 d01c49e0fbbbd71e8ed612323f4b1c88 292 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 5 288 28.553 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AFE_0194 d01c49e0fbbbd71e8ed612323f4b1c88 292 Gene3D G3DSA:3.40.50.150 101 291 8.7E-49 T 12-10-2018 AFE_0194 d01c49e0fbbbd71e8ed612323f4b1c88 292 SUPERFAMILY SSF53335 83 269 1.64E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0194 d01c49e0fbbbd71e8ed612323f4b1c88 292 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 5 281 1.8E-60 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AFE_0653 75ab14d184e68b742245828399ffb600 408 Pfam PF07143 CrtC N-terminal lipocalin domain 98 267 3.7E-52 T 12-10-2018 IPR010791 AttH domain AFE_0653 75ab14d184e68b742245828399ffb600 408 SUPERFAMILY SSF159245 78 400 1.22E-105 T 12-10-2018 AFE_0653 75ab14d184e68b742245828399ffb600 408 Gene3D G3DSA:2.40.370.10 272 405 2.1E-44 T 12-10-2018 IPR023374 AttH-like domain superfamily AFE_0653 75ab14d184e68b742245828399ffb600 408 Pfam PF17186 Lipocalin-like domain 272 400 1.1E-38 T 12-10-2018 AFE_0653 75ab14d184e68b742245828399ffb600 408 Gene3D G3DSA:2.40.370.10 86 271 4.0E-63 T 12-10-2018 IPR023374 AttH-like domain superfamily AFE_3211 c37fad31bd75a03d84b6f86947b1f101 294 Gene3D G3DSA:3.90.1530.30 38 101 9.9E-25 T 12-10-2018 AFE_3211 c37fad31bd75a03d84b6f86947b1f101 294 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 24 196 8.8E-56 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 AFE_3211 c37fad31bd75a03d84b6f86947b1f101 294 Gene3D G3DSA:1.10.10.2830 102 215 1.2E-35 T 12-10-2018 AFE_3211 c37fad31bd75a03d84b6f86947b1f101 294 Pfam PF02195 ParB-like nuclease domain 26 115 6.3E-27 T 12-10-2018 IPR003115 ParB/Sulfiredoxin AFE_3211 c37fad31bd75a03d84b6f86947b1f101 294 SUPERFAMILY SSF110849 24 156 8.37E-32 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily AFE_3211 c37fad31bd75a03d84b6f86947b1f101 294 SMART SM00470 25 115 8.9E-36 T 12-10-2018 IPR003115 ParB/Sulfiredoxin AFE_2566 b856ce02d23785fc7e8af228ec77d2ed 403 Pfam PF01098 Cell cycle protein 19 360 3.0E-103 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_2566 b856ce02d23785fc7e8af228ec77d2ed 403 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 318 342 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_2566 b856ce02d23785fc7e8af228ec77d2ed 403 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 16 359 3.0E-126 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_2566 b856ce02d23785fc7e8af228ec77d2ed 403 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 9 363 26.276 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_0785 f187c0518891471d5cd2e4563f105157 539 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 17 531 8.8E-108 T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 AFE_0785 f187c0518891471d5cd2e4563f105157 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 37 62 1.7E-27 T 12-10-2018 AFE_0785 f187c0518891471d5cd2e4563f105157 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 132 151 1.7E-27 T 12-10-2018 AFE_0785 f187c0518891471d5cd2e4563f105157 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 230 246 1.7E-27 T 12-10-2018 AFE_0785 f187c0518891471d5cd2e4563f105157 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 259 278 1.7E-27 T 12-10-2018 AFE_0785 f187c0518891471d5cd2e4563f105157 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 377 395 1.7E-27 T 12-10-2018 AFE_0785 f187c0518891471d5cd2e4563f105157 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 353 371 1.7E-27 T 12-10-2018 AFE_0785 f187c0518891471d5cd2e4563f105157 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 408 423 1.7E-27 T 12-10-2018 AFE_0785 f187c0518891471d5cd2e4563f105157 539 Pfam PF01019 Gamma-glutamyltranspeptidase 30 534 1.3E-125 T 12-10-2018 AFE_0785 f187c0518891471d5cd2e4563f105157 539 SUPERFAMILY SSF56235 11 536 1.25E-143 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_0785 f187c0518891471d5cd2e4563f105157 539 Gene3D G3DSA:1.10.246.130 246 350 3.6E-17 T 12-10-2018 AFE_0785 f187c0518891471d5cd2e4563f105157 539 Gene3D G3DSA:3.60.20.40 353 538 1.0E-61 T 12-10-2018 AFE_0438 72e5d770386aa00fa733ac5c9d4fdaff 167 Gene3D G3DSA:3.90.45.10 1 167 1.2E-50 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFE_0438 72e5d770386aa00fa733ac5c9d4fdaff 167 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 156 2.1E-42 T 12-10-2018 IPR023635 Peptide deformylase AFE_0438 72e5d770386aa00fa733ac5c9d4fdaff 167 Pfam PF01327 Polypeptide deformylase 4 156 8.9E-47 T 12-10-2018 IPR023635 Peptide deformylase AFE_0438 72e5d770386aa00fa733ac5c9d4fdaff 167 SUPERFAMILY SSF56420 2 164 1.24E-51 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFE_0438 72e5d770386aa00fa733ac5c9d4fdaff 167 PRINTS PR01576 Peptide deformylase signature 125 154 3.1E-26 T 12-10-2018 IPR023635 Peptide deformylase AFE_0438 72e5d770386aa00fa733ac5c9d4fdaff 167 PRINTS PR01576 Peptide deformylase signature 94 105 3.1E-26 T 12-10-2018 IPR023635 Peptide deformylase AFE_0438 72e5d770386aa00fa733ac5c9d4fdaff 167 PRINTS PR01576 Peptide deformylase signature 106 124 3.1E-26 T 12-10-2018 IPR023635 Peptide deformylase AFE_0438 72e5d770386aa00fa733ac5c9d4fdaff 167 PRINTS PR01576 Peptide deformylase signature 34 63 3.1E-26 T 12-10-2018 IPR023635 Peptide deformylase AFE_0438 72e5d770386aa00fa733ac5c9d4fdaff 167 Hamap MF_00163 Peptide deformylase [def]. 2 167 27.156 T 12-10-2018 IPR023635 Peptide deformylase AFE_0438 72e5d770386aa00fa733ac5c9d4fdaff 167 PIRSF PIRSF004749 1 167 1.1E-51 T 12-10-2018 IPR023635 Peptide deformylase AFE_2216 00afe7c7865e6ece5a33514883649ee3 189 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 78 167 1.4E-19 T 12-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 AFE_2216 00afe7c7865e6ece5a33514883649ee3 189 Gene3D G3DSA:1.20.120.1630 2 189 9.7E-38 T 12-10-2018 AFE_0562 07f043b92606cde5f5558ec2cc977632 287 Pfam PF08340 Domain of unknown function (DUF1732) 203 287 3.1E-33 T 12-10-2018 IPR013551 Domain of unknown function DUF1732 AFE_0562 07f043b92606cde5f5558ec2cc977632 287 Pfam PF03755 YicC-like family, N-terminal region 2 153 4.7E-37 T 12-10-2018 IPR013527 YicC-like, N-terminal AFE_0562 07f043b92606cde5f5558ec2cc977632 287 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 287 2.0E-82 T 12-10-2018 IPR005229 Conserved hypothetical protein CHP00255 AFE_0070 0cb6ce683352a66e26034dc9fb35b1f3 272 SUPERFAMILY SSF48452 148 265 2.6E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0070 0cb6ce683352a66e26034dc9fb35b1f3 272 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 149 265 8.3E-38 T 12-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal AFE_0070 0cb6ce683352a66e26034dc9fb35b1f3 272 Pfam PF13432 Tetratricopeptide repeat 154 205 2.4E-6 T 12-10-2018 AFE_0070 0cb6ce683352a66e26034dc9fb35b1f3 272 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 3 268 17.394 T 12-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 AFE_0070 0cb6ce683352a66e26034dc9fb35b1f3 272 Gene3D G3DSA:1.25.40.10 148 270 5.1E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0070 0cb6ce683352a66e26034dc9fb35b1f3 272 Pfam PF13174 Tetratricopeptide repeat 223 255 2.7E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_2869 90a6aa12459d61221cadea17d2eb6aea 148 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFE_2869 90a6aa12459d61221cadea17d2eb6aea 148 Gene3D G3DSA:2.40.50.100 7 133 1.3E-32 T 12-10-2018 AFE_2869 90a6aa12459d61221cadea17d2eb6aea 148 SUPERFAMILY SSF51230 9 122 1.24E-27 T 12-10-2018 IPR011053 Single hybrid motif AFE_2869 90a6aa12459d61221cadea17d2eb6aea 148 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 137 28.848 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AFE_2869 90a6aa12459d61221cadea17d2eb6aea 148 Pfam PF01597 Glycine cleavage H-protein 14 132 4.4E-33 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate AFE_1468 be3214355d4e764cc2319ffa9162ed14 159 Pfam PF00578 AhpC/TSA family 8 137 1.1E-36 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFE_1468 be3214355d4e764cc2319ffa9162ed14 159 SUPERFAMILY SSF52833 6 158 4.23E-49 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1468 be3214355d4e764cc2319ffa9162ed14 159 Gene3D G3DSA:3.40.30.10 4 157 5.9E-46 T 12-10-2018 AFE_1468 be3214355d4e764cc2319ffa9162ed14 159 PIRSF PIRSF000239 1 158 7.2E-31 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFE_2153 8c9b71f21c242a30f2621edaa5703d03 515 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 136 1.0E-5 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2153 8c9b71f21c242a30f2621edaa5703d03 515 SUPERFAMILY SSF143243 29 174 5.62E-22 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2153 8c9b71f21c242a30f2621edaa5703d03 515 Gene3D G3DSA:1.10.645.20 161 514 1.2E-95 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2153 8c9b71f21c242a30f2621edaa5703d03 515 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 44 137 2.2E-10 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2153 8c9b71f21c242a30f2621edaa5703d03 515 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 286 438 1.0E-25 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2153 8c9b71f21c242a30f2621edaa5703d03 515 SUPERFAMILY SSF56762 170 514 3.27E-88 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_1504 7f78e750735a43b1247eaad70b609641 110 Hamap MF_00529 Nitrogenase-stabilizing/protective protein NifW [nifW]. 2 103 20.958 T 12-10-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 AFE_1504 7f78e750735a43b1247eaad70b609641 110 Pfam PF03206 Nitrogen fixation protein NifW 6 101 4.1E-32 T 12-10-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 AFE_1504 7f78e750735a43b1247eaad70b609641 110 PIRSF PIRSF005790 1 105 1.3E-31 T 12-10-2018 IPR004893 Nitrogen fixation protein NifW GO:0009399 AFE_0081 9525112a1ac1e69fa358c2e3af6fe2c4 346 SUPERFAMILY SSF53756 12 343 2.83E-66 T 12-10-2018 AFE_0081 9525112a1ac1e69fa358c2e3af6fe2c4 346 Gene3D G3DSA:3.40.50.2000 77 338 7.4E-56 T 12-10-2018 AFE_0081 9525112a1ac1e69fa358c2e3af6fe2c4 346 Pfam PF13439 Glycosyltransferase Family 4 77 146 3.7E-10 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_0081 9525112a1ac1e69fa358c2e3af6fe2c4 346 Gene3D G3DSA:3.40.50.2000 144 324 7.4E-56 T 12-10-2018 AFE_0081 9525112a1ac1e69fa358c2e3af6fe2c4 346 Pfam PF00534 Glycosyl transferases group 1 160 322 1.1E-29 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1900 4d9367078f8a8905591158be4e5fdc6e 182 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 66 4.4E-16 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFE_1900 4d9367078f8a8905591158be4e5fdc6e 182 Gene3D G3DSA:1.20.120.1760 3 165 4.9E-12 T 12-10-2018 AFE_1900 4d9367078f8a8905591158be4e5fdc6e 182 PIRSF PIRSF000847 1 180 3.1E-44 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFE_1900 4d9367078f8a8905591158be4e5fdc6e 182 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 44 66 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFE_1328 4b4689ad1868b0da5b4ca692125fb1ae 439 Pfam PF07282 Putative transposase DNA-binding domain 319 385 2.1E-8 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFE_1328 4b4689ad1868b0da5b4ca692125fb1ae 439 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 263 344 2.0E-14 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFE_2722 5190b17c5f518fdce9d34ca85a8c9d6a 292 Pfam PF01136 Peptidase family U32 95 256 5.8E-13 T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFE_2777 4505dbe12d5f2c833fe02e9f0fe38cb4 206 Pfam PF12146 Serine aminopeptidase, S33 28 135 7.7E-15 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 AFE_2777 4505dbe12d5f2c833fe02e9f0fe38cb4 206 SUPERFAMILY SSF53474 6 206 9.98E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_2777 4505dbe12d5f2c833fe02e9f0fe38cb4 206 Gene3D G3DSA:3.40.50.1820 3 206 9.1E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_2945 a889f02d3f2b45b41e28a2ba381df3d4 141 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 13 140 35.04 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AFE_2945 a889f02d3f2b45b41e28a2ba381df3d4 141 Pfam PF01641 SelR domain 21 138 6.9E-48 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AFE_2945 a889f02d3f2b45b41e28a2ba381df3d4 141 SUPERFAMILY SSF51316 18 139 2.56E-52 T 12-10-2018 IPR011057 Mss4-like superfamily AFE_2945 a889f02d3f2b45b41e28a2ba381df3d4 141 Gene3D G3DSA:2.170.150.20 15 141 2.4E-55 T 12-10-2018 AFE_2945 a889f02d3f2b45b41e28a2ba381df3d4 141 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 19 138 1.1E-49 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 AFE_2833 52f627bf8de8e285ad4bb4e543afedea 236 Gene3D G3DSA:3.40.50.1360 1 229 3.6E-61 T 12-10-2018 AFE_2833 52f627bf8de8e285ad4bb4e543afedea 236 SUPERFAMILY SSF100950 9 220 2.27E-53 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFE_2833 52f627bf8de8e285ad4bb4e543afedea 236 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 15 217 1.1E-58 T 12-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 AFE_2833 52f627bf8de8e285ad4bb4e543afedea 236 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 13 206 4.9E-49 T 12-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 Pfam PF13360 PQQ-like domain 104 252 1.6E-11 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 Pfam PF13360 PQQ-like domain 270 393 1.6E-18 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 SMART SM00564 213 244 0.012 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 SMART SM00564 82 117 14.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 SMART SM00564 295 326 0.037 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 SMART SM00564 173 204 0.42 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 SMART SM00564 41 74 250.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 SMART SM00564 253 286 0.052 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 Gene3D G3DSA:2.130.10.10 155 395 8.1E-45 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 SUPERFAMILY SSF50998 27 340 1.57E-44 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AFE_2251 b976f3f16bb96d01eb840a996c8fe5a0 395 Gene3D G3DSA:2.130.10.10 27 154 1.4E-18 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_0303 470bf5e0220ebe4aa06d5ef5f561a57f 190 SMART SM00671 88 123 6.1E-9 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0303 470bf5e0220ebe4aa06d5ef5f561a57f 190 SMART SM00671 52 87 0.0029 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0303 470bf5e0220ebe4aa06d5ef5f561a57f 190 SMART SM00671 124 159 5.0E-11 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0303 470bf5e0220ebe4aa06d5ef5f561a57f 190 Pfam PF08238 Sel1 repeat 88 122 2.1E-8 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0303 470bf5e0220ebe4aa06d5ef5f561a57f 190 Pfam PF08238 Sel1 repeat 124 159 5.5E-9 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0303 470bf5e0220ebe4aa06d5ef5f561a57f 190 Pfam PF08238 Sel1 repeat 65 87 6.3E-5 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0303 470bf5e0220ebe4aa06d5ef5f561a57f 190 Gene3D G3DSA:1.25.40.10 44 186 1.4E-38 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0303 470bf5e0220ebe4aa06d5ef5f561a57f 190 SUPERFAMILY SSF81901 56 167 4.27E-32 T 12-10-2018 AFE_2013 41fe61ee844bf2d857ef03236d3e28db 145 SUPERFAMILY SSF46785 11 141 3.13E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2013 41fe61ee844bf2d857ef03236d3e28db 145 Pfam PF12802 MarR family 36 92 2.6E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFE_2013 41fe61ee844bf2d857ef03236d3e28db 145 Gene3D G3DSA:1.10.10.10 2 143 2.8E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2013 41fe61ee844bf2d857ef03236d3e28db 145 SMART SM00347 29 129 2.5E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFE_2987 b096a76ffa9d0a315d4cd418038652d1 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 454 4.6E-65 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain AFE_2987 b096a76ffa9d0a315d4cd418038652d1 543 SUPERFAMILY SSF53850 46 526 2.17E-81 T 12-10-2018 AFE_2987 b096a76ffa9d0a315d4cd418038652d1 543 Gene3D G3DSA:3.40.190.10 49 522 2.3E-89 T 12-10-2018 AFE_2987 b096a76ffa9d0a315d4cd418038652d1 543 Gene3D G3DSA:3.10.105.10 288 512 2.3E-89 T 12-10-2018 AFE_2987 b096a76ffa9d0a315d4cd418038652d1 543 PIRSF PIRSF002741 30 536 3.7E-64 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFE_2987 b096a76ffa9d0a315d4cd418038652d1 543 Gene3D G3DSA:3.90.76.10 68 193 2.3E-89 T 12-10-2018 AFE_1928 c892edaf43e43e2f3096f2cfbd773a31 339 Gene3D G3DSA:1.10.20.140 135 206 7.2E-87 T 12-10-2018 AFE_1928 c892edaf43e43e2f3096f2cfbd773a31 339 SUPERFAMILY SSF52540 29 176 1.0E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1928 c892edaf43e43e2f3096f2cfbd773a31 339 Pfam PF01715 IPP transferase 62 303 5.3E-73 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFE_1928 c892edaf43e43e2f3096f2cfbd773a31 339 SUPERFAMILY SSF52540 28 255 1.08E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1928 c892edaf43e43e2f3096f2cfbd773a31 339 Gene3D G3DSA:3.40.50.300 32 304 7.2E-87 T 12-10-2018 AFE_1928 c892edaf43e43e2f3096f2cfbd773a31 339 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 28 320 27.945 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFE_1928 c892edaf43e43e2f3096f2cfbd773a31 339 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 28 311 1.1E-83 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFE_2408 19807540ca4653fc924c176a6a95511a 809 SMART SM00487 438 616 2.8E-26 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_2408 19807540ca4653fc924c176a6a95511a 809 SUPERFAMILY SSF52540 350 601 2.43E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2408 19807540ca4653fc924c176a6a95511a 809 Pfam PF04851 Type III restriction enzyme, res subunit 442 583 2.7E-18 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFE_2408 19807540ca4653fc924c176a6a95511a 809 SUPERFAMILY SSF52540 545 772 2.21E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2408 19807540ca4653fc924c176a6a95511a 809 Gene3D G3DSA:3.40.50.300 621 804 2.6E-27 T 12-10-2018 AFE_2408 19807540ca4653fc924c176a6a95511a 809 Gene3D G3DSA:3.40.50.300 436 608 8.0E-37 T 12-10-2018 AFE_2287 2c9efbe620ea21c8a78e0f7027f9efbf 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 78 1.7E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFE_2287 2c9efbe620ea21c8a78e0f7027f9efbf 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 1.4E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFE_2287 2c9efbe620ea21c8a78e0f7027f9efbf 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 1.4E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFE_2287 2c9efbe620ea21c8a78e0f7027f9efbf 250 SUPERFAMILY SSF46785 10 81 6.59E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2287 2c9efbe620ea21c8a78e0f7027f9efbf 250 SMART SM00866 99 244 0.0031 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFE_2287 2c9efbe620ea21c8a78e0f7027f9efbf 250 SUPERFAMILY SSF64288 66 248 7.85E-21 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFE_2287 2c9efbe620ea21c8a78e0f7027f9efbf 250 SMART SM00345 19 78 4.3E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFE_2287 2c9efbe620ea21c8a78e0f7027f9efbf 250 Gene3D G3DSA:1.10.10.10 13 79 2.3E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2287 2c9efbe620ea21c8a78e0f7027f9efbf 250 Gene3D G3DSA:3.40.1410.10 86 248 1.8E-15 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFE_2287 2c9efbe620ea21c8a78e0f7027f9efbf 250 Pfam PF07702 UTRA domain 136 244 1.5E-10 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 Pfam PF00344 SecY translocase 77 419 7.4E-118 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 Gene3D G3DSA:1.10.3370.10 10 431 4.1E-165 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 Hamap MF_01465 Protein translocase subunit SecY [secY]. 11 435 30.25 T 12-10-2018 IPR026593 Protein translocase subunit SecY AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 21 430 3.8E-129 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 ProSitePatterns PS00755 Protein secY signature 1. 77 96 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 SUPERFAMILY SSF103491 13 426 4.05E-128 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 24 42 2.7E-92 T 12-10-2018 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 156 181 2.7E-92 T 12-10-2018 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 274 293 2.7E-92 T 12-10-2018 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 182 205 2.7E-92 T 12-10-2018 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 372 390 2.7E-92 T 12-10-2018 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 117 140 2.7E-92 T 12-10-2018 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 317 339 2.7E-92 T 12-10-2018 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 404 422 2.7E-92 T 12-10-2018 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 76 96 2.7E-92 T 12-10-2018 AFE_0347 0280d87248629306b66cc2b3a31f6dce 443 PIRSF PIRSF004557 8 442 1.2E-122 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFE_1070 de46b785864a4f992fb0929fa78245d9 91 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 1.1E-11 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1070 de46b785864a4f992fb0929fa78245d9 91 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 1.1E-11 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1070 de46b785864a4f992fb0929fa78245d9 91 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 1.1E-11 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1070 de46b785864a4f992fb0929fa78245d9 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AFE_1070 de46b785864a4f992fb0929fa78245d9 91 SUPERFAMILY SSF47729 3 90 3.09E-26 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_1070 de46b785864a4f992fb0929fa78245d9 91 Pfam PF00216 Bacterial DNA-binding protein 4 90 2.3E-27 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1070 de46b785864a4f992fb0929fa78245d9 91 SMART SM00411 3 91 7.2E-27 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1070 de46b785864a4f992fb0929fa78245d9 91 Gene3D G3DSA:4.10.520.10 1 91 2.1E-29 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_0140 687920157800777f7491faa34d4a1923 461 Gene3D G3DSA:3.30.70.2740 336 417 1.4E-14 T 12-10-2018 AFE_0140 687920157800777f7491faa34d4a1923 461 SUPERFAMILY SSF56176 5 216 3.88E-65 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFE_0140 687920157800777f7491faa34d4a1923 461 Gene3D G3DSA:1.10.45.10 418 458 5.4E-12 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFE_0140 687920157800777f7491faa34d4a1923 461 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 457 5.4E-61 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFE_0140 687920157800777f7491faa34d4a1923 461 SUPERFAMILY SSF55103 219 459 7.52E-60 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFE_0140 687920157800777f7491faa34d4a1923 461 Gene3D G3DSA:3.30.465.40 3 235 6.2E-67 T 12-10-2018 AFE_0140 687920157800777f7491faa34d4a1923 461 Pfam PF01565 FAD binding domain 42 178 7.1E-36 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFE_1466 eaf4b1e8d0cb828ce97368db545531ce 254 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 187 200 6.2E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_1466 eaf4b1e8d0cb828ce97368db545531ce 254 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 6.2E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_1466 eaf4b1e8d0cb828ce97368db545531ce 254 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 6.2E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_1466 eaf4b1e8d0cb828ce97368db545531ce 254 SUPERFAMILY SSF56784 3 220 7.15E-41 T 12-10-2018 IPR036412 HAD-like superfamily AFE_1466 eaf4b1e8d0cb828ce97368db545531ce 254 Gene3D G3DSA:1.10.150.240 17 95 1.3E-68 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFE_1466 eaf4b1e8d0cb828ce97368db545531ce 254 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 196 2.5E-21 T 12-10-2018 AFE_1466 eaf4b1e8d0cb828ce97368db545531ce 254 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 151 197 3.3E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_1466 eaf4b1e8d0cb828ce97368db545531ce 254 Gene3D G3DSA:3.40.50.1000 5 215 1.3E-68 T 12-10-2018 IPR023214 HAD superfamily AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 Gene3D G3DSA:3.90.640.10 192 265 1.9E-129 T 12-10-2018 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 74 97 2.2E-63 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 138 157 2.2E-63 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 54 72 2.2E-63 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 193 213 2.2E-63 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 306 332 2.2E-63 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 11 341 1.6E-158 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 SUPERFAMILY SSF53067 11 154 8.46E-39 T 12-10-2018 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 Gene3D G3DSA:3.30.420.40 15 333 1.9E-129 T 12-10-2018 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 SUPERFAMILY SSF53067 156 336 2.18E-47 T 12-10-2018 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 Gene3D G3DSA:3.30.420.40 160 323 1.9E-129 T 12-10-2018 AFE_2562 a67ba17a99f53e59be7477cf80418e11 348 Pfam PF06723 MreB/Mbl protein 13 340 5.1E-148 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFE_0862 4651a963742dd3f5720120cc442cf707 387 SUPERFAMILY SSF111369 193 261 3.01E-7 T 12-10-2018 AFE_0862 4651a963742dd3f5720120cc442cf707 387 Gene3D G3DSA:2.40.30.170 230 352 9.1E-27 T 12-10-2018 AFE_0862 4651a963742dd3f5720120cc442cf707 387 Pfam PF00529 HlyD membrane-fusion protein of T1SS 33 339 2.9E-8 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_0862 4651a963742dd3f5720120cc442cf707 387 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 286 1.1E-16 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_0862 4651a963742dd3f5720120cc442cf707 387 Gene3D G3DSA:2.40.50.100 59 188 1.9E-10 T 12-10-2018 AFE_0862 4651a963742dd3f5720120cc442cf707 387 Gene3D G3DSA:1.10.287.470 91 185 1.9E-10 T 12-10-2018 AFE_0271 889623fe03bc7895aa2ee360d8920e06 227 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 16 226 28.026 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AFE_0271 889623fe03bc7895aa2ee360d8920e06 227 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 42 226 9.6E-49 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AFE_0271 889623fe03bc7895aa2ee360d8920e06 227 Gene3D G3DSA:3.40.50.150 22 226 3.6E-58 T 12-10-2018 AFE_0271 889623fe03bc7895aa2ee360d8920e06 227 Pfam PF02390 Putative methyltransferase 52 221 2.4E-47 T 12-10-2018 AFE_0271 889623fe03bc7895aa2ee360d8920e06 227 SUPERFAMILY SSF53335 35 224 7.72E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_1977 29181a2a19df76e8ce1ce03ee0f70d40 403 SUPERFAMILY SSF103473 16 395 2.09E-56 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_1977 29181a2a19df76e8ce1ce03ee0f70d40 403 Gene3D G3DSA:1.20.1250.20 14 202 2.6E-21 T 12-10-2018 AFE_1977 29181a2a19df76e8ce1ce03ee0f70d40 403 Gene3D G3DSA:1.20.1250.20 219 401 1.3E-19 T 12-10-2018 AFE_1977 29181a2a19df76e8ce1ce03ee0f70d40 403 Pfam PF07690 Major Facilitator Superfamily 27 359 2.3E-35 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_0108 86577a33561088acd60498bbac9dffde 519 Pfam PF02321 Outer membrane efflux protein 90 281 1.8E-16 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_0108 86577a33561088acd60498bbac9dffde 519 Pfam PF02321 Outer membrane efflux protein 306 489 3.8E-22 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_0108 86577a33561088acd60498bbac9dffde 519 SUPERFAMILY SSF56954 22 494 1.96E-86 T 12-10-2018 AFE_0108 86577a33561088acd60498bbac9dffde 519 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 30 491 1.2E-100 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 AFE_0108 86577a33561088acd60498bbac9dffde 519 Gene3D G3DSA:2.20.200.10 124 380 1.0E-103 T 12-10-2018 AFE_0108 86577a33561088acd60498bbac9dffde 519 Gene3D G3DSA:1.20.1600.10 77 492 1.0E-103 T 12-10-2018 AFE_2152 7929dc57f4c8c0bf099819eb3444678d 484 Pfam PF00361 Proton-conducting membrane transporter 124 415 1.4E-50 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2152 7929dc57f4c8c0bf099819eb3444678d 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 327 346 5.1E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2152 7929dc57f4c8c0bf099819eb3444678d 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 379 405 5.1E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2152 7929dc57f4c8c0bf099819eb3444678d 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 129 148 5.1E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2152 7929dc57f4c8c0bf099819eb3444678d 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 238 262 5.1E-13 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2800 3daf0c3ddf1079b7e14273087ca94c62 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 122 3.8E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFE_2800 3daf0c3ddf1079b7e14273087ca94c62 132 SUPERFAMILY SSF54593 1 125 3.85E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFE_2800 3daf0c3ddf1079b7e14273087ca94c62 132 Gene3D G3DSA:3.10.180.10 7 130 3.2E-39 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFE_0181 e6b9d35c3a5d8b6ef23ad751208a1c02 393 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 4 363 4.5E-96 T 12-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 AFE_0181 e6b9d35c3a5d8b6ef23ad751208a1c02 393 Gene3D G3DSA:3.30.420.40 8 359 3.0E-103 T 12-10-2018 AFE_0181 e6b9d35c3a5d8b6ef23ad751208a1c02 393 Gene3D G3DSA:3.30.420.40 137 324 3.0E-103 T 12-10-2018 AFE_0181 e6b9d35c3a5d8b6ef23ad751208a1c02 393 SUPERFAMILY SSF53067 67 326 2.76E-11 T 12-10-2018 AFE_0181 e6b9d35c3a5d8b6ef23ad751208a1c02 393 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 364 34.43 T 12-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 AFE_3111 2c5576ecb4f0f31655bda737253f7c76 242 Gene3D G3DSA:1.10.760.10 21 197 5.6E-15 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_3111 2c5576ecb4f0f31655bda737253f7c76 242 SUPERFAMILY SSF46626 25 195 1.0E-40 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_3111 2c5576ecb4f0f31655bda737253f7c76 242 Pfam PF02167 Cytochrome C1 family 32 229 1.5E-15 T 12-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 AFE_2196 1d8d5df84bff48cc73fda200c3da98e9 150 Gene3D G3DSA:3.10.590.10 1 149 7.8E-59 T 12-10-2018 AFE_2196 1d8d5df84bff48cc73fda200c3da98e9 150 Pfam PF01878 EVE domain 2 147 6.7E-51 T 12-10-2018 IPR002740 EVE domain AFE_2196 1d8d5df84bff48cc73fda200c3da98e9 150 SUPERFAMILY SSF88697 1 150 4.29E-58 T 12-10-2018 IPR015947 PUA-like superfamily AFE_0264 b3695be9bdd90b7352f002123924a19a 349 Pfam PF00437 Type II/IV secretion system protein 12 269 8.4E-46 T 12-10-2018 IPR001482 Type II/IV secretion system protein AFE_0264 b3695be9bdd90b7352f002123924a19a 349 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 342 4.3E-150 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 AFE_0264 b3695be9bdd90b7352f002123924a19a 349 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 12-10-2018 IPR001482 Type II/IV secretion system protein AFE_0264 b3695be9bdd90b7352f002123924a19a 349 Gene3D G3DSA:3.30.450.90 1 100 1.2E-33 T 12-10-2018 AFE_0264 b3695be9bdd90b7352f002123924a19a 349 Gene3D G3DSA:3.40.50.300 101 349 5.5E-101 T 12-10-2018 AFE_0264 b3695be9bdd90b7352f002123924a19a 349 SUPERFAMILY SSF52540 5 337 3.76E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0264 b3695be9bdd90b7352f002123924a19a 349 SMART SM00382 122 256 4.7E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2611 321719059c8feb84cd9673776fb5d314 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2611 321719059c8feb84cd9673776fb5d314 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.703 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2611 321719059c8feb84cd9673776fb5d314 119 SUPERFAMILY SSF74731 3 116 8.89E-48 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2611 321719059c8feb84cd9673776fb5d314 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.4E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2611 321719059c8feb84cd9673776fb5d314 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.4E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2611 321719059c8feb84cd9673776fb5d314 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.4E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2611 321719059c8feb84cd9673776fb5d314 119 Pfam PF00453 Ribosomal protein L20 3 109 1.9E-47 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2611 321719059c8feb84cd9673776fb5d314 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 71 7.0E-15 T 12-10-2018 AFE_2611 321719059c8feb84cd9673776fb5d314 119 Gene3D G3DSA:1.10.1900.20 56 118 4.6E-28 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2611 321719059c8feb84cd9673776fb5d314 119 Gene3D G3DSA:1.10.720.90 2 55 2.5E-24 T 12-10-2018 AFE_2611 321719059c8feb84cd9673776fb5d314 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.0E-48 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1907 73e2c75a45b20c1bd45cf93122908d74 311 Pfam PF00698 Acyl transferase domain 7 279 3.9E-38 T 12-10-2018 IPR014043 Acyl transferase AFE_1907 73e2c75a45b20c1bd45cf93122908d74 311 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 5 291 9.0E-110 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 AFE_1907 73e2c75a45b20c1bd45cf93122908d74 311 SUPERFAMILY SSF55048 131 198 1.7E-16 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding AFE_1907 73e2c75a45b20c1bd45cf93122908d74 311 Gene3D G3DSA:3.30.70.250 126 198 1.2E-101 T 12-10-2018 AFE_1907 73e2c75a45b20c1bd45cf93122908d74 311 Gene3D G3DSA:3.40.366.10 7 285 1.2E-101 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 AFE_1907 73e2c75a45b20c1bd45cf93122908d74 311 PIRSF PIRSF000446 3 311 3.4E-113 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 AFE_1907 73e2c75a45b20c1bd45cf93122908d74 311 SUPERFAMILY SSF52151 5 310 1.41E-76 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFE_1907 73e2c75a45b20c1bd45cf93122908d74 311 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8 298 6.8E-43 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain AFE_2438 dabedb56f9b22ca6a5715e6177c26b63 94 Pfam PF09851 Short C-terminal domain 66 92 1.8E-7 T 12-10-2018 IPR018649 SHOCT domain AFE_0636 384d9e987bffdd3b76e3aac8c11c1a1c 277 Pfam PF02673 Bacitracin resistance protein BacA 8 269 3.2E-71 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFE_0636 384d9e987bffdd3b76e3aac8c11c1a1c 277 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 275 15.127 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFE_3287 8828931c6210abe2a7f2e968dd7eccd5 113 PIRSF PIRSF004761 1 113 1.4E-36 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFE_3287 8828931c6210abe2a7f2e968dd7eccd5 113 Gene3D G3DSA:3.30.2320.80 1 113 1.9E-33 T 12-10-2018 AFE_3287 8828931c6210abe2a7f2e968dd7eccd5 113 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 113 6.1E-35 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFE_3287 8828931c6210abe2a7f2e968dd7eccd5 113 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 113 22.564 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFE_3287 8828931c6210abe2a7f2e968dd7eccd5 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 112 4.8E-34 T 12-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFE_0402 f433ae3325f05d4c6505ee56616a9000 135 Gene3D G3DSA:3.10.180.10 1 127 5.9E-48 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFE_0402 f433ae3325f05d4c6505ee56616a9000 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 123 5.3E-25 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFE_0402 f433ae3325f05d4c6505ee56616a9000 135 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 128 1.5E-63 T 12-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 AFE_0402 f433ae3325f05d4c6505ee56616a9000 135 SUPERFAMILY SSF54593 1 129 7.92E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFE_0402 f433ae3325f05d4c6505ee56616a9000 135 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 12-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 AFE_1586 dbf1630a3724e4c4aaf3439dbfac62cf 73 SUPERFAMILY SSF47729 3 65 4.71E-9 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_1586 dbf1630a3724e4c4aaf3439dbfac62cf 73 Pfam PF00216 Bacterial DNA-binding protein 33 65 6.4E-5 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1586 dbf1630a3724e4c4aaf3439dbfac62cf 73 Gene3D G3DSA:4.10.520.10 26 67 1.1E-6 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_2282 4611aff9c1febfe1a145c517908f0780 260 SMART SM00382 33 231 7.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2282 4611aff9c1febfe1a145c517908f0780 260 Gene3D G3DSA:3.40.50.300 6 260 9.1E-74 T 12-10-2018 AFE_2282 4611aff9c1febfe1a145c517908f0780 260 TIGRFAM TIGR02323 CP_lyasePhnK: phosphonate C-P lyase system protein PhnK 7 258 1.5E-94 T 12-10-2018 IPR012700 Phosphonate C-P lyase system, PhnK AFE_2282 4611aff9c1febfe1a145c517908f0780 260 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2282 4611aff9c1febfe1a145c517908f0780 260 SUPERFAMILY SSF52540 7 256 2.51E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2282 4611aff9c1febfe1a145c517908f0780 260 PIRSF PIRSF037116 1 260 1.8E-117 T 12-10-2018 IPR012700 Phosphonate C-P lyase system, PhnK AFE_2282 4611aff9c1febfe1a145c517908f0780 260 Pfam PF00005 ABC transporter 24 182 1.9E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_1680 37f5ea313be47bf78144ac982d4a7a38 211 Gene3D G3DSA:3.40.50.300 4 210 8.3E-47 T 12-10-2018 AFE_1680 37f5ea313be47bf78144ac982d4a7a38 211 PIRSF PIRSF009320 3 210 4.1E-35 T 12-10-2018 AFE_1680 37f5ea313be47bf78144ac982d4a7a38 211 SUPERFAMILY SSF52540 5 208 3.17E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1680 37f5ea313be47bf78144ac982d4a7a38 211 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 185 5.6E-16 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFE_2703 6dcc0fdc245ebe05a3e6815a2613d5ae 409 SUPERFAMILY SSF52540 144 386 2.36E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2703 6dcc0fdc245ebe05a3e6815a2613d5ae 409 Gene3D G3DSA:3.40.50.300 143 384 4.6E-29 T 12-10-2018 AFE_2703 6dcc0fdc245ebe05a3e6815a2613d5ae 409 Pfam PF16968 Pilus assembly protein TadZ N-terminal 19 119 1.7E-6 T 12-10-2018 IPR031580 Pilus assembly protein TadZ, N-terminal AFE_2703 6dcc0fdc245ebe05a3e6815a2613d5ae 409 Gene3D G3DSA:3.40.50.2300 16 141 5.2E-14 T 12-10-2018 AFE_2019 78f5dc2dbdaadb68c93b0eff4a376c96 325 Gene3D G3DSA:3.30.110.70 108 164 9.4E-6 T 12-10-2018 AFE_2019 78f5dc2dbdaadb68c93b0eff4a376c96 325 Pfam PF01906 Putative heavy-metal-binding 112 161 3.5E-5 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 AFE_2019 78f5dc2dbdaadb68c93b0eff4a376c96 325 SUPERFAMILY SSF117782 91 163 1.31E-8 T 12-10-2018 IPR035439 UPF0145 domain superfamily AFE_0840 c1148d629972a36e0085962f8f145a2b 937 SUPERFAMILY SSF52540 275 879 3.04E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0840 c1148d629972a36e0085962f8f145a2b 937 Gene3D G3DSA:3.40.50.300 274 572 2.8E-12 T 12-10-2018 AFE_0840 c1148d629972a36e0085962f8f145a2b 937 Gene3D G3DSA:3.40.50.300 592 887 1.5E-9 T 12-10-2018 AFE_0684 3a307557fc4c5a75983e3c9f8c9ec2fc 489 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 274 280 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFE_0684 3a307557fc4c5a75983e3c9f8c9ec2fc 489 SUPERFAMILY SSF53335 5 483 3.95E-118 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0684 3a307557fc4c5a75983e3c9f8c9ec2fc 489 Pfam PF02384 N-6 DNA Methylase 142 456 8.4E-76 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 AFE_0684 3a307557fc4c5a75983e3c9f8c9ec2fc 489 Pfam PF12161 HsdM N-terminal domain 8 132 1.4E-13 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain AFE_0684 3a307557fc4c5a75983e3c9f8c9ec2fc 489 Gene3D G3DSA:3.40.50.150 140 456 2.6E-83 T 12-10-2018 AFE_0684 3a307557fc4c5a75983e3c9f8c9ec2fc 489 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 300 324 4.2E-21 T 12-10-2018 AFE_0684 3a307557fc4c5a75983e3c9f8c9ec2fc 489 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 188 202 4.2E-21 T 12-10-2018 AFE_0684 3a307557fc4c5a75983e3c9f8c9ec2fc 489 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 164 180 4.2E-21 T 12-10-2018 AFE_0684 3a307557fc4c5a75983e3c9f8c9ec2fc 489 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 271 283 4.2E-21 T 12-10-2018 AFE_0684 3a307557fc4c5a75983e3c9f8c9ec2fc 489 Gene3D G3DSA:1.20.1260.30 1 138 8.0E-43 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 SUPERFAMILY SSF55021 326 411 2.24E-25 T 12-10-2018 AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 SUPERFAMILY SSF55021 408 501 2.52E-25 T 12-10-2018 AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 305 1.8E-87 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 Gene3D G3DSA:3.40.1020.10 327 503 3.1E-70 T 12-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 318 407 8.2E-25 T 12-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 415 501 4.4E-23 T 12-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 SUPERFAMILY SSF53686 11 351 4.32E-107 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 Gene3D G3DSA:3.40.50.1100 49 145 2.6E-140 T 12-10-2018 AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 4 501 2.2E-242 T 12-10-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 41 54 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AFE_0722 f8047f58043b541d0202f9c16a1940e1 506 Gene3D G3DSA:3.40.50.1100 13 316 2.6E-140 T 12-10-2018 AFE_0573 6856d407a2a4ab24a5eca30810474626 202 Pfam PF01871 AMMECR1 23 189 6.5E-44 T 12-10-2018 IPR002733 AMMECR1 domain AFE_0573 6856d407a2a4ab24a5eca30810474626 202 Gene3D G3DSA:3.30.700.20 18 192 8.6E-51 T 12-10-2018 IPR027485 AMMECR1, N-terminal AFE_0573 6856d407a2a4ab24a5eca30810474626 202 Gene3D G3DSA:3.30.1490.150 118 190 8.6E-51 T 12-10-2018 AFE_0573 6856d407a2a4ab24a5eca30810474626 202 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 17 197 2.1E-31 T 12-10-2018 IPR023473 AMMECR1 AFE_0573 6856d407a2a4ab24a5eca30810474626 202 SUPERFAMILY SSF143447 15 193 5.1E-56 T 12-10-2018 IPR036071 AMMECR1 domain superfamily AFE_0573 6856d407a2a4ab24a5eca30810474626 202 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 20 190 3.7E-57 T 12-10-2018 IPR027623 AmmeMemoRadiSam system protein A AFE_0670 f601ddd7b7a74ed0e69aceb298ee0c82 256 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 7 243 8.9E-70 T 12-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 AFE_0670 f601ddd7b7a74ed0e69aceb298ee0c82 256 SUPERFAMILY SSF75217 6 168 2.22E-38 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFE_0670 f601ddd7b7a74ed0e69aceb298ee0c82 256 Gene3D G3DSA:1.10.8.590 172 254 8.1E-26 T 12-10-2018 AFE_0670 f601ddd7b7a74ed0e69aceb298ee0c82 256 Gene3D G3DSA:3.40.1280.10 5 170 1.2E-62 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFE_0670 f601ddd7b7a74ed0e69aceb298ee0c82 256 PIRSF PIRSF004808 4 250 1.4E-73 T 12-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 AFE_0670 f601ddd7b7a74ed0e69aceb298ee0c82 256 Pfam PF00588 SpoU rRNA Methylase family 9 158 9.4E-37 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFE_2998 edc92f503530fcda275ade878f4d7fce 799 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 166 7.5E-9 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain AFE_2998 edc92f503530fcda275ade878f4d7fce 799 SUPERFAMILY SSF56935 54 798 5.19E-72 T 12-10-2018 AFE_2998 edc92f503530fcda275ade878f4d7fce 799 Gene3D G3DSA:2.170.130.10 55 179 4.1E-9 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_2998 edc92f503530fcda275ade878f4d7fce 799 Pfam PF00593 TonB dependent receptor 424 795 1.8E-37 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_2227 62ed3268a27c51e8e9829941075e3cc3 208 SUPERFAMILY SSF56784 48 196 5.93E-33 T 12-10-2018 IPR036412 HAD-like superfamily AFE_2227 62ed3268a27c51e8e9829941075e3cc3 208 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 162 5.8E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_2227 62ed3268a27c51e8e9829941075e3cc3 208 Pfam PF13419 Haloacid dehalogenase-like hydrolase 45 168 3.3E-23 T 12-10-2018 AFE_2227 62ed3268a27c51e8e9829941075e3cc3 208 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 103 168 4.4E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFE_2227 62ed3268a27c51e8e9829941075e3cc3 208 Gene3D G3DSA:3.40.50.1000 63 197 5.9E-34 T 12-10-2018 IPR023214 HAD superfamily AFE_3305 a509f8167cc9b4f2bda944db417e4af2 277 SUPERFAMILY SSF53613 12 266 3.27E-66 T 12-10-2018 IPR029056 Ribokinase-like AFE_3305 a509f8167cc9b4f2bda944db417e4af2 277 Pfam PF08543 Phosphomethylpyrimidine kinase 22 257 4.0E-68 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFE_3305 a509f8167cc9b4f2bda944db417e4af2 277 Gene3D G3DSA:3.40.1190.20 4 269 1.5E-78 T 12-10-2018 IPR029056 Ribokinase-like AFE_0043 1df480935d851861c0c1e23263e8c391 336 Gene3D G3DSA:3.40.190.10 174 293 1.0E-22 T 12-10-2018 AFE_0043 1df480935d851861c0c1e23263e8c391 336 SUPERFAMILY SSF53850 81 333 1.09E-39 T 12-10-2018 AFE_0043 1df480935d851861c0c1e23263e8c391 336 Pfam PF13531 Bacterial extracellular solute-binding protein 84 330 4.8E-53 T 12-10-2018 AFE_0043 1df480935d851861c0c1e23263e8c391 336 Gene3D G3DSA:3.40.190.10 85 330 1.0E-22 T 12-10-2018 AFE_1099 2ca84c239ee340b1d8a60909f1c20ecb 113 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 9 104 2.9E-19 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 AFE_1099 2ca84c239ee340b1d8a60909f1c20ecb 113 SUPERFAMILY SSF50118 5 109 1.42E-28 T 12-10-2018 AFE_1099 2ca84c239ee340b1d8a60909f1c20ecb 113 Gene3D G3DSA:2.30.30.110 1 113 2.1E-40 T 12-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor AFE_1057 e15243fc351829c3b414d460549d94cd 549 SMART SM00028 69 102 3.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1057 e15243fc351829c3b414d460549d94cd 549 SMART SM00028 103 136 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1057 e15243fc351829c3b414d460549d94cd 549 SMART SM00028 35 68 0.026 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_1057 e15243fc351829c3b414d460549d94cd 549 Pfam PF13469 Sulfotransferase family 334 508 1.9E-34 T 12-10-2018 AFE_1057 e15243fc351829c3b414d460549d94cd 549 Gene3D G3DSA:3.40.50.300 322 547 2.4E-52 T 12-10-2018 AFE_1057 e15243fc351829c3b414d460549d94cd 549 SUPERFAMILY SSF48452 4 194 1.38E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1057 e15243fc351829c3b414d460549d94cd 549 Pfam PF13432 Tetratricopeptide repeat 4 65 4.2E-5 T 12-10-2018 AFE_1057 e15243fc351829c3b414d460549d94cd 549 SUPERFAMILY SSF52540 331 544 3.54E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0679 27b69fd896de08cfbf534874f0449d65 64 SUPERFAMILY SSF140319 1 62 4.97E-23 T 12-10-2018 IPR036762 IscX-like superfamily AFE_0679 27b69fd896de08cfbf534874f0449d65 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 2 64 1.4E-30 T 12-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 AFE_0679 27b69fd896de08cfbf534874f0449d65 64 Gene3D G3DSA:1.10.10.600 1 64 3.5E-26 T 12-10-2018 IPR036762 IscX-like superfamily AFE_0679 27b69fd896de08cfbf534874f0449d65 64 Pfam PF04384 Iron-sulphur cluster assembly 1 63 4.2E-30 T 12-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 AFE_0679 27b69fd896de08cfbf534874f0449d65 64 PIRSF PIRSF039003 1 64 1.7E-30 T 12-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 Gene3D G3DSA:3.40.50.300 210 441 9.9E-81 T 12-10-2018 AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 SUPERFAMILY SSF52540 209 444 4.2E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 Pfam PF00271 Helicase conserved C-terminal domain 470 578 7.9E-17 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 SMART SM00487 260 450 4.2E-34 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 Pfam PF17191 RecG wedge domain 17 174 9.1E-15 T 12-10-2018 IPR033454 RecG, wedge domain AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 Gene3D G3DSA:3.40.50.300 448 620 3.5E-53 T 12-10-2018 AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 Pfam PF00270 DEAD/DEAH box helicase 268 424 2.8E-15 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 SMART SM00490 496 579 1.6E-19 T 12-10-2018 IPR001650 Helicase, C-terminal AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 SUPERFAMILY SSF52540 443 644 2.72E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 Gene3D G3DSA:2.40.50.140 50 143 8.7E-10 T 12-10-2018 AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 34 651 2.0E-207 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 AFE_0568 9a641daef27c1db468097c55d7a9f1d5 684 SUPERFAMILY SSF50249 9 177 9.94E-31 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1344 5a3e54468f3dde20bbfe4444ec4f2c97 488 Pfam PF13440 Polysaccharide biosynthesis protein 35 316 4.5E-18 T 12-10-2018 AFE_0163 a56d5ac868d5f1cb54f215602ef41acf 306 SMART SM00382 32 212 3.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0163 a56d5ac868d5f1cb54f215602ef41acf 306 Pfam PF00005 ABC transporter 24 165 3.4E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0163 a56d5ac868d5f1cb54f215602ef41acf 306 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_0163 a56d5ac868d5f1cb54f215602ef41acf 306 SUPERFAMILY SSF52540 5 233 1.07E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0163 a56d5ac868d5f1cb54f215602ef41acf 306 Gene3D G3DSA:3.40.50.300 2 235 2.8E-63 T 12-10-2018 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 684 729 5.1E-15 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 784 830 8.1E-13 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 637 676 9.2E-7 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 530 575 3.5E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 580 628 1.2E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 735 780 6.0E-14 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 497 1.8E-151 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 SUPERFAMILY SSF101904 524 840 3.4E-106 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 7 832 24.099 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 830 0.0 T 12-10-2018 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Gene3D G3DSA:2.120.10.90 522 831 6.2E-123 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 SMART SM00434 11 490 2.2E-272 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 SUPERFAMILY SSF56719 30 513 3.4E-178 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Gene3D G3DSA:3.30.1360.40 236 333 4.7E-222 T 12-10-2018 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Gene3D G3DSA:3.90.199.10 33 512 4.7E-222 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AFE_0894 3cef20b438a76d20965ca1c8fc036751 845 Gene3D G3DSA:1.10.268.10 370 484 4.7E-222 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFE_1880 3dbc221c3687a88bb369c91bb632e0ea 515 SUPERFAMILY SSF56954 7 486 4.84E-99 T 12-10-2018 AFE_1880 3dbc221c3687a88bb369c91bb632e0ea 515 Pfam PF02321 Outer membrane efflux protein 83 272 1.8E-22 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_1880 3dbc221c3687a88bb369c91bb632e0ea 515 Pfam PF02321 Outer membrane efflux protein 298 481 3.6E-30 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_1880 3dbc221c3687a88bb369c91bb632e0ea 515 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 483 1.1E-122 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 AFE_1880 3dbc221c3687a88bb369c91bb632e0ea 515 Gene3D G3DSA:2.20.200.10 120 372 3.2E-116 T 12-10-2018 AFE_1880 3dbc221c3687a88bb369c91bb632e0ea 515 Gene3D G3DSA:1.20.1600.10 73 484 3.2E-116 T 12-10-2018 AFE_0567 e6849bfc1a7d99a69e27aa49d1ce1bd1 71 Gene3D G3DSA:1.10.3910.10 8 67 1.1E-10 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily AFE_0567 e6849bfc1a7d99a69e27aa49d1ce1bd1 71 SUPERFAMILY SSF140683 13 60 5.62E-8 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily AFE_1923 2e542000178a9678d3124891337df65d 283 Gene3D G3DSA:3.40.1190.20 9 277 4.5E-69 T 12-10-2018 IPR029056 Ribokinase-like AFE_1923 2e542000178a9678d3124891337df65d 283 SUPERFAMILY SSF53613 13 276 3.78E-61 T 12-10-2018 IPR029056 Ribokinase-like AFE_1923 2e542000178a9678d3124891337df65d 283 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 213 223 - T 12-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site AFE_1923 2e542000178a9678d3124891337df65d 283 Pfam PF01256 Carbohydrate kinase 31 270 3.1E-38 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFE_1923 2e542000178a9678d3124891337df65d 283 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 10 274 6.1E-48 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFE_1923 2e542000178a9678d3124891337df65d 283 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 8 278 19.625 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFE_3296 90c8a9ff18bcf299cc2de2e8039c3524 458 Pfam PF00083 Sugar (and other) transporter 28 450 1.7E-60 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFE_3296 90c8a9ff18bcf299cc2de2e8039c3524 458 Gene3D G3DSA:1.20.1250.20 24 451 1.2E-86 T 12-10-2018 AFE_3296 90c8a9ff18bcf299cc2de2e8039c3524 458 PRINTS PR00171 Sugar transporter signature 33 43 1.5E-5 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_3296 90c8a9ff18bcf299cc2de2e8039c3524 458 PRINTS PR00171 Sugar transporter signature 116 135 1.5E-5 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_3296 90c8a9ff18bcf299cc2de2e8039c3524 458 PRINTS PR00171 Sugar transporter signature 376 388 1.5E-5 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_3296 90c8a9ff18bcf299cc2de2e8039c3524 458 ProSitePatterns PS00217 Sugar transport proteins signature 2. 121 146 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFE_3296 90c8a9ff18bcf299cc2de2e8039c3524 458 SUPERFAMILY SSF103473 12 449 6.28E-73 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_1687 f1e493ba4f04aa5e7c3a45e7a9a76aaa 82 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 77 3.5E-21 T 12-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml AFE_1687 f1e493ba4f04aa5e7c3a45e7a9a76aaa 82 Gene3D G3DSA:2.40.50.220 1 82 1.3E-31 T 12-10-2018 IPR036677 EutN/Ccml superfamily AFE_1687 f1e493ba4f04aa5e7c3a45e7a9a76aaa 82 TIGRFAM TIGR02703 carboxysome_A: carboxysome peptide A 1 80 5.4E-51 T 12-10-2018 IPR014076 Carboxysome peptide A AFE_1687 f1e493ba4f04aa5e7c3a45e7a9a76aaa 82 SUPERFAMILY SSF159133 1 81 2.75E-24 T 12-10-2018 IPR036677 EutN/Ccml superfamily AFE_1687 f1e493ba4f04aa5e7c3a45e7a9a76aaa 82 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 10 82 8.0E-36 T 12-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml AFE_1440 dfc5f303ec4963b9bb5c6948d77b6feb 237 Gene3D G3DSA:1.20.58.220 1 117 2.0E-41 T 12-10-2018 IPR038078 PhoU-like domain superfamily AFE_1440 dfc5f303ec4963b9bb5c6948d77b6feb 237 SUPERFAMILY SSF109755 9 233 1.47E-68 T 12-10-2018 AFE_1440 dfc5f303ec4963b9bb5c6948d77b6feb 237 Pfam PF01895 PhoU domain 24 108 1.2E-22 T 12-10-2018 IPR026022 PhoU domain AFE_1440 dfc5f303ec4963b9bb5c6948d77b6feb 237 Pfam PF01895 PhoU domain 131 213 1.1E-16 T 12-10-2018 IPR026022 PhoU domain AFE_1440 dfc5f303ec4963b9bb5c6948d77b6feb 237 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 9 221 1.8E-73 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AFE_1440 dfc5f303ec4963b9bb5c6948d77b6feb 237 Gene3D G3DSA:1.20.58.220 120 235 1.9E-33 T 12-10-2018 IPR038078 PhoU-like domain superfamily AFE_1440 dfc5f303ec4963b9bb5c6948d77b6feb 237 PIRSF PIRSF003107 5 226 5.3E-68 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AFE_1962 51af7fecdfa1038fa64c66204da37bb0 91 PRINTS PR00606 Class ID cytochrome C signature 22 35 7.4E-17 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFE_1962 51af7fecdfa1038fa64c66204da37bb0 91 PRINTS PR00606 Class ID cytochrome C signature 60 70 7.4E-17 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFE_1962 51af7fecdfa1038fa64c66204da37bb0 91 PRINTS PR00606 Class ID cytochrome C signature 7 20 7.4E-17 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFE_1962 51af7fecdfa1038fa64c66204da37bb0 91 PRINTS PR00606 Class ID cytochrome C signature 45 58 7.4E-17 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFE_1962 51af7fecdfa1038fa64c66204da37bb0 91 PRINTS PR00606 Class ID cytochrome C signature 71 81 7.4E-17 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 AFE_1962 51af7fecdfa1038fa64c66204da37bb0 91 SUPERFAMILY SSF46626 7 82 3.1E-15 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_1962 51af7fecdfa1038fa64c66204da37bb0 91 Gene3D G3DSA:1.10.760.10 3 83 9.3E-28 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 Gene3D G3DSA:3.30.70.1170 180 237 1.2E-12 T 12-10-2018 AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 SUPERFAMILY SSF53335 151 430 1.02E-69 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 Gene3D G3DSA:1.10.287.730 153 179 1.2E-6 T 12-10-2018 AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 Gene3D G3DSA:3.40.50.150 238 431 8.4E-61 T 12-10-2018 AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 Pfam PF01029 NusB family 42 136 1.5E-9 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 7.7E-29 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 258 268 7.7E-29 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 413 430 7.7E-29 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 7.7E-29 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 229 243 7.7E-29 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 Pfam PF01189 16S rRNA methyltransferase RsmB/F 247 428 3.5E-57 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 20 431 5.5E-101 T 12-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 Gene3D G3DSA:1.10.940.10 15 150 1.4E-24 T 12-10-2018 IPR035926 NusB-like superfamily AFE_0021 e0e822b321cf23b40a78b5ded63f020e 434 SUPERFAMILY SSF48013 19 156 1.36E-20 T 12-10-2018 IPR035926 NusB-like superfamily AFE_0898 de22ea01a532dd1b03ae4fd18ba849d2 365 SUPERFAMILY SSF53383 14 357 8.74E-82 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_0898 de22ea01a532dd1b03ae4fd18ba849d2 365 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 12 364 1.2E-96 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFE_0898 de22ea01a532dd1b03ae4fd18ba849d2 365 Gene3D G3DSA:3.90.1150.10 27 358 6.5E-110 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0898 de22ea01a532dd1b03ae4fd18ba849d2 365 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 365 57.103 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFE_0898 de22ea01a532dd1b03ae4fd18ba849d2 365 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 225 234 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 AFE_0898 de22ea01a532dd1b03ae4fd18ba849d2 365 Pfam PF00155 Aminotransferase class I and II 36 354 6.6E-51 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFE_0898 de22ea01a532dd1b03ae4fd18ba849d2 365 Gene3D G3DSA:3.40.640.10 49 273 6.5E-110 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_1993 bbf44ae79a6a04a5f218b0f0c65ec21e 301 Gene3D G3DSA:1.10.10.10 9 94 8.3E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1993 bbf44ae79a6a04a5f218b0f0c65ec21e 301 Gene3D G3DSA:3.40.190.290 95 300 3.3E-38 T 12-10-2018 AFE_1993 bbf44ae79a6a04a5f218b0f0c65ec21e 301 SUPERFAMILY SSF46785 6 116 4.23E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1993 bbf44ae79a6a04a5f218b0f0c65ec21e 301 SUPERFAMILY SSF53850 94 297 1.19E-32 T 12-10-2018 AFE_1993 bbf44ae79a6a04a5f218b0f0c65ec21e 301 Pfam PF03466 LysR substrate binding domain 92 292 3.4E-34 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_1993 bbf44ae79a6a04a5f218b0f0c65ec21e 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 66 1.3E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_1993 bbf44ae79a6a04a5f218b0f0c65ec21e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_1993 bbf44ae79a6a04a5f218b0f0c65ec21e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_1993 bbf44ae79a6a04a5f218b0f0c65ec21e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0604 5818fc206717b4b108f148ecc0f1dd0c 296 SUPERFAMILY SSF81345 15 271 3.01E-22 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFE_0604 5818fc206717b4b108f148ecc0f1dd0c 296 Pfam PF00950 ABC 3 transport family 14 271 9.5E-34 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AFE_2717 dca6682060e34e69d3e17d013e14f100 133 Pfam PF10861 Protein of Unknown function (DUF2784) 6 125 6.6E-32 T 12-10-2018 IPR021218 Protein of unknown function DUF2784 AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 TIGRFAM TIGR00498 lexA: repressor LexA 1 200 6.6E-66 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 Gene3D G3DSA:2.10.109.10 81 202 4.6E-41 T 12-10-2018 AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 112 122 8.2E-12 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 123 134 8.2E-12 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 153 165 8.2E-12 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 SUPERFAMILY SSF51306 76 200 4.71E-36 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 SUPERFAMILY SSF46785 3 69 4.67E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 Gene3D G3DSA:1.10.10.10 1 69 2.6E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 Pfam PF00717 Peptidase S24-like 115 183 2.9E-13 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 Hamap MF_00015 LexA repressor [lexA]. 3 202 30.388 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AFE_1868 8aeaeabb804420370f94c1cbdcfd04b1 205 Pfam PF01726 LexA DNA binding domain 1 65 1.0E-22 T 12-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 AFE_0331 9e359c9798ea2e21c3be2f44cc18d560 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 5.7E-22 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0331 9e359c9798ea2e21c3be2f44cc18d560 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 5.7E-22 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0331 9e359c9798ea2e21c3be2f44cc18d560 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 5.7E-22 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0331 9e359c9798ea2e21c3be2f44cc18d560 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 2 91 3.1E-42 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFE_0331 9e359c9798ea2e21c3be2f44cc18d560 91 Pfam PF00203 Ribosomal protein S19 3 83 3.7E-34 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0331 9e359c9798ea2e21c3be2f44cc18d560 91 PIRSF PIRSF002144 1 91 5.8E-32 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0331 9e359c9798ea2e21c3be2f44cc18d560 91 SUPERFAMILY SSF54570 3 83 6.54E-33 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0331 9e359c9798ea2e21c3be2f44cc18d560 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0331 9e359c9798ea2e21c3be2f44cc18d560 91 Gene3D G3DSA:3.30.860.10 1 91 2.5E-37 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0331 9e359c9798ea2e21c3be2f44cc18d560 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.094 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_1740 c38d936bac45bc31f01b34ff6323b419 458 SUPERFAMILY SSF56024 264 443 3.59E-38 T 12-10-2018 AFE_1740 c38d936bac45bc31f01b34ff6323b419 458 SUPERFAMILY SSF56024 96 287 9.16E-42 T 12-10-2018 AFE_1740 c38d936bac45bc31f01b34ff6323b419 458 Gene3D G3DSA:3.30.870.10 289 430 1.1E-24 T 12-10-2018 AFE_1740 c38d936bac45bc31f01b34ff6323b419 458 SMART SM00155 371 398 0.037 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFE_1740 c38d936bac45bc31f01b34ff6323b419 458 SMART SM00155 192 219 0.063 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFE_1740 c38d936bac45bc31f01b34ff6323b419 458 Gene3D G3DSA:3.30.870.10 97 281 5.0E-39 T 12-10-2018 AFE_1740 c38d936bac45bc31f01b34ff6323b419 458 Pfam PF13091 PLD-like domain 117 255 1.1E-14 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFE_1740 c38d936bac45bc31f01b34ff6323b419 458 Pfam PF13091 PLD-like domain 301 425 5.2E-27 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFE_3243 42929c9afdebb105c3f1630b37dd1f0d 338 SUPERFAMILY SSF52418 74 331 9.03E-86 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFE_3243 42929c9afdebb105c3f1630b37dd1f0d 338 Pfam PF00591 Glycosyl transferase family, a/b domain 75 324 4.1E-85 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFE_3243 42929c9afdebb105c3f1630b37dd1f0d 338 Gene3D G3DSA:3.40.1030.10 71 337 1.5E-99 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFE_3243 42929c9afdebb105c3f1630b37dd1f0d 338 Gene3D G3DSA:1.20.970.10 1 70 6.7E-22 T 12-10-2018 AFE_3243 42929c9afdebb105c3f1630b37dd1f0d 338 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 64 2.2E-17 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFE_3243 42929c9afdebb105c3f1630b37dd1f0d 338 SUPERFAMILY SSF47648 4 69 4.06E-18 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFE_3243 42929c9afdebb105c3f1630b37dd1f0d 338 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 331 1.0E-116 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AFE_3243 42929c9afdebb105c3f1630b37dd1f0d 338 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 334 35.816 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 6 90 1.5E-21 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 134 150 1.6E-19 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 328 349 1.6E-19 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 158 171 1.6E-19 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 134 1.6E-19 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 579 26.117 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 SUPERFAMILY SSF47323 454 579 1.44E-36 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 SUPERFAMILY SSF55190 14 110 4.19E-23 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 129 138 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 Pfam PF05746 DALR anticodon binding domain 459 579 1.6E-36 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 SMART SM01016 3 90 5.3E-31 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 Gene3D G3DSA:3.40.50.620 119 453 2.1E-155 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 SMART SM00836 459 579 9.9E-56 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 Pfam PF00750 tRNA synthetases class I (R) 286 426 3.2E-9 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 Pfam PF00750 tRNA synthetases class I (R) 113 178 1.9E-7 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 Gene3D G3DSA:3.30.1360.70 1 110 2.5E-23 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 Gene3D G3DSA:1.10.730.10 454 579 2.1E-155 T 12-10-2018 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 28 579 1.1E-132 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFE_0170 32ad73de51bdfcfe66f1c96d10c5031c 579 SUPERFAMILY SSF52374 115 470 2.11E-87 T 12-10-2018 AFE_0317 ea46acac024c610b658d0fb68a7b52f2 173 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 24.967 T 12-10-2018 IPR022973 Ribosomal protein L10 AFE_0317 ea46acac024c610b658d0fb68a7b52f2 173 Pfam PF00466 Ribosomal protein L10 6 100 2.8E-22 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 AFE_0317 ea46acac024c610b658d0fb68a7b52f2 173 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 12-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0317 ea46acac024c610b658d0fb68a7b52f2 173 SUPERFAMILY SSF160369 4 170 7.19E-51 T 12-10-2018 AFE_0317 ea46acac024c610b658d0fb68a7b52f2 173 Gene3D G3DSA:3.30.70.1730 4 133 1.6E-34 T 12-10-2018 AFE_0317 ea46acac024c610b658d0fb68a7b52f2 173 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 26 164 2.0E-5 T 12-10-2018 AFE_3096 62febcec35d16c4150ffc1a75422378f 111 Gene3D G3DSA:2.20.130.30 37 111 7.2E-17 T 12-10-2018 AFE_3096 62febcec35d16c4150ffc1a75422378f 111 Pfam PF11191 Protein of unknown function (DUF2782) 36 111 2.1E-24 T 12-10-2018 IPR021357 Protein of unknown function DUF2782 AFE_1449 53f3e9497270c0e87183b45ff39952ee 271 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 225 251 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 AFE_1449 53f3e9497270c0e87183b45ff39952ee 271 Pfam PF01148 Cytidylyltransferase family 4 264 7.1E-51 T 12-10-2018 AFE_2195 169dddca4b17060467e37abacf50fb4a 104 SMART SM01219 1 104 3.0E-34 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AFE_2195 169dddca4b17060467e37abacf50fb4a 104 Pfam PF01491 Frataxin-like domain 2 100 3.7E-21 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AFE_2195 169dddca4b17060467e37abacf50fb4a 104 Gene3D G3DSA:3.30.920.10 1 104 4.2E-25 T 12-10-2018 IPR036524 Frataxin/CyaY superfamily GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AFE_2195 169dddca4b17060467e37abacf50fb4a 104 SUPERFAMILY SSF55387 1 101 4.53E-24 T 12-10-2018 AFE_2195 169dddca4b17060467e37abacf50fb4a 104 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 3 102 1.6E-29 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AFE_1786 4b3ae53c46b18c1c2aef3f257f03cc33 274 Gene3D G3DSA:1.10.620.20 38 208 7.8E-17 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 AFE_1786 4b3ae53c46b18c1c2aef3f257f03cc33 274 SUPERFAMILY SSF47240 7 190 7.75E-28 T 12-10-2018 IPR009078 Ferritin-like superfamily AFE_1018 75b1ac436a4e8365096e98a14cc20e57 182 SUPERFAMILY SSF52833 12 177 1.14E-15 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1018 75b1ac436a4e8365096e98a14cc20e57 182 Pfam PF13098 Thioredoxin-like domain 42 176 2.1E-9 T 12-10-2018 IPR012336 Thioredoxin-like fold AFE_1018 75b1ac436a4e8365096e98a14cc20e57 182 Gene3D G3DSA:3.40.30.10 42 180 2.3E-19 T 12-10-2018 AFE_0624 1e33a5159066482248365efdc96f6261 470 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 Gene3D G3DSA:3.30.499.20 5 287 5.0E-97 T 12-10-2018 AFE_0624 1e33a5159066482248365efdc96f6261 470 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 466 2.1E-228 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 468 59.052 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 Pfam PF00330 Aconitase family (aconitate hydratase) 8 459 3.0E-155 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 PRINTS PR00415 Aconitase family signature 83 96 3.2E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 PRINTS PR00415 Aconitase family signature 196 209 3.2E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 PRINTS PR00415 Aconitase family signature 120 133 3.2E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 PRINTS PR00415 Aconitase family signature 344 355 3.2E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 PRINTS PR00415 Aconitase family signature 109 117 3.2E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 PRINTS PR00415 Aconitase family signature 210 223 3.2E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 PRINTS PR00415 Aconitase family signature 401 414 3.2E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 PRINTS PR00415 Aconitase family signature 287 301 3.2E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 PRINTS PR00415 Aconitase family signature 134 149 3.2E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 Gene3D G3DSA:3.30.499.10 326 470 1.6E-48 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 AFE_0624 1e33a5159066482248365efdc96f6261 470 SUPERFAMILY SSF53732 3 467 1.44E-160 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 AFE_0967 8e2e3a709d72276477a7a94d84e56923 1137 SUPERFAMILY SSF53300 368 542 4.08E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_2125 81e0beef1127fb92cbbbd6edaa9c7710 347 SUPERFAMILY SSF48576 9 322 3.74E-57 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFE_2125 81e0beef1127fb92cbbbd6edaa9c7710 347 Gene3D G3DSA:1.10.600.10 7 335 1.6E-98 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFE_2125 81e0beef1127fb92cbbbd6edaa9c7710 347 Pfam PF00494 Squalene/phytoene synthase 19 308 1.0E-53 T 12-10-2018 AFE_2125 81e0beef1127fb92cbbbd6edaa9c7710 347 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 156 171 - T 12-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFE_1734 76a58f03c4ca66519a6b47289c45579a 98 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 4 92 2.5E-33 T 12-10-2018 IPR014057 Uncharacterized protein HI1420 AFE_1734 76a58f03c4ca66519a6b47289c45579a 98 SUPERFAMILY SSF47413 32 89 3.28E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 62 5.3E-15 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 8 164 32.169 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 118 140 1.2E-45 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 91 107 1.2E-45 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 8 26 1.2E-45 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 55 79 1.2E-45 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 26 47 1.2E-45 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 10 162 1.1E-52 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 SUPERFAMILY SSF52374 8 162 4.56E-39 T 12-10-2018 AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 Gene3D G3DSA:3.40.50.620 1 164 2.7E-49 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2755 a6439190e2ce0bca07f91f510ebaa550 174 Pfam PF01467 Cytidylyltransferase-like 11 139 9.3E-15 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFE_1544 8fbfaaba384fa7539678c2a5ab883a50 284 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 103 2.9E-17 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFE_1544 8fbfaaba384fa7539678c2a5ab883a50 284 SUPERFAMILY SSF54675 4 104 2.12E-18 T 12-10-2018 AFE_1544 8fbfaaba384fa7539678c2a5ab883a50 284 Gene3D G3DSA:3.20.20.70 121 272 7.2E-69 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1544 8fbfaaba384fa7539678c2a5ab883a50 284 SUPERFAMILY SSF51690 105 281 4.32E-38 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFE_1544 8fbfaaba384fa7539678c2a5ab883a50 284 PIRSF PIRSF006250 1 283 6.9E-56 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 AFE_1544 8fbfaaba384fa7539678c2a5ab883a50 284 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 105 277 2.8E-33 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 AFE_1544 8fbfaaba384fa7539678c2a5ab883a50 284 Gene3D G3DSA:3.90.1170.20 8 276 7.2E-69 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 AFE_1544 8fbfaaba384fa7539678c2a5ab883a50 284 TIGRFAM TIGR01334 modD: modD protein 1 281 4.8E-71 T 12-10-2018 IPR006242 Putative pyrophosphorylase ModD GO:0016763 AFE_0481 298f30a107e83c2a4ec86de85ecc4570 414 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 414 1.7E-148 T 12-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 AFE_0481 298f30a107e83c2a4ec86de85ecc4570 414 Pfam PF12704 MacB-like periplasmic core domain 26 243 9.6E-18 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFE_0481 298f30a107e83c2a4ec86de85ecc4570 414 Pfam PF02687 FtsX-like permease family 301 406 9.4E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFE_1366 87e24dca36422c21c9989f5e3ea0c5c5 480 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 4 477 1.4E-173 T 12-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AFE_1366 87e24dca36422c21c9989f5e3ea0c5c5 480 Pfam PF01050 Mannose-6-phosphate isomerase 323 473 1.6E-65 T 12-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AFE_1366 87e24dca36422c21c9989f5e3ea0c5c5 480 Pfam PF00483 Nucleotidyl transferase 6 287 9.0E-54 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFE_1366 87e24dca36422c21c9989f5e3ea0c5c5 480 Gene3D G3DSA:2.60.120.10 368 468 6.7E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_1366 87e24dca36422c21c9989f5e3ea0c5c5 480 SUPERFAMILY SSF53448 4 286 1.6E-67 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_1366 87e24dca36422c21c9989f5e3ea0c5c5 480 SUPERFAMILY SSF51182 194 477 4.13E-79 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_1366 87e24dca36422c21c9989f5e3ea0c5c5 480 Gene3D G3DSA:3.90.550.10 4 358 8.1E-115 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_1210 097654fc0b0ea264f75e7c0329ba2d33 248 Gene3D G3DSA:2.60.120.620 65 243 4.9E-55 T 12-10-2018 AFE_1210 097654fc0b0ea264f75e7c0329ba2d33 248 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 143 243 2.3E-17 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 AFE_1210 097654fc0b0ea264f75e7c0329ba2d33 248 SMART SM00702 63 243 3.8E-45 T 12-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 SUPERFAMILY SSF53633 16 266 2.09E-57 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 Pfam PF00696 Amino acid kinase family 17 244 2.0E-39 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 PRINTS PR00474 Glutamate 5-kinase family signature 127 148 6.0E-41 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 PRINTS PR00474 Glutamate 5-kinase family signature 159 186 6.0E-41 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 PRINTS PR00474 Glutamate 5-kinase family signature 220 240 6.0E-41 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 PRINTS PR00474 Glutamate 5-kinase family signature 53 67 6.0E-41 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 PRINTS PR00474 Glutamate 5-kinase family signature 87 115 6.0E-41 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 TIGRFAM TIGR01027 proB: glutamate 5-kinase 17 284 5.4E-79 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 PIRSF PIRSF000729 11 294 2.5E-81 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 Gene3D G3DSA:3.40.1160.10 7 271 1.3E-77 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 Hamap MF_00456 Glutamate 5-kinase [proB]. 16 270 30.561 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_2464 a624b9229d7f4cda6d83a5e63eb0d321 322 ProSitePatterns PS00902 Glutamate 5-kinase signature. 218 235 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_2959 da38aae07bce07fa8bc1860c21b9e727 93 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 75 2.0E-30 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AFE_2959 da38aae07bce07fa8bc1860c21b9e727 93 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 4.2E-44 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AFE_2959 da38aae07bce07fa8bc1860c21b9e727 93 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 28.574 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AFE_2959 da38aae07bce07fa8bc1860c21b9e727 93 SUPERFAMILY SSF111148 1 89 9.81E-40 T 12-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 AFE_2959 da38aae07bce07fa8bc1860c21b9e727 93 PIRSF PIRSF029827 1 90 5.5E-40 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 AFE_2959 da38aae07bce07fa8bc1860c21b9e727 93 Gene3D G3DSA:1.10.3880.10 1 90 1.4E-42 T 12-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 AFE_0071 a35abb232f6dd30fde6bd485b36f6a91 192 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 4 186 28.398 T 12-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 AFE_0071 a35abb232f6dd30fde6bd485b36f6a91 192 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 83 186 9.2E-42 T 12-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 AFE_0071 a35abb232f6dd30fde6bd485b36f6a91 192 ProSitePatterns PS01068 OmpA-like domain. 118 162 - T 12-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 AFE_0071 a35abb232f6dd30fde6bd485b36f6a91 192 Gene3D G3DSA:3.30.1330.60 67 186 3.8E-36 T 12-10-2018 IPR036737 OmpA-like domain superfamily AFE_0071 a35abb232f6dd30fde6bd485b36f6a91 192 SUPERFAMILY SSF103088 81 186 1.96E-32 T 12-10-2018 IPR036737 OmpA-like domain superfamily AFE_0071 a35abb232f6dd30fde6bd485b36f6a91 192 PRINTS PR01021 OMPA domain signature 116 131 3.4E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFE_0071 a35abb232f6dd30fde6bd485b36f6a91 192 PRINTS PR01021 OMPA domain signature 86 108 3.4E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFE_0071 a35abb232f6dd30fde6bd485b36f6a91 192 PRINTS PR01021 OMPA domain signature 131 147 3.4E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFE_0071 a35abb232f6dd30fde6bd485b36f6a91 192 Pfam PF00691 OmpA family 86 180 2.3E-18 T 12-10-2018 IPR006665 OmpA-like domain AFE_0343 03a56d8bb370e7d7b4f732f0eca73e35 117 SUPERFAMILY SSF53137 3 115 5.45E-50 T 12-10-2018 AFE_0343 03a56d8bb370e7d7b4f732f0eca73e35 117 Gene3D G3DSA:3.30.420.100 1 117 6.0E-43 T 12-10-2018 AFE_0343 03a56d8bb370e7d7b4f732f0eca73e35 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 4 117 2.8E-37 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0343 03a56d8bb370e7d7b4f732f0eca73e35 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 27.752 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0343 03a56d8bb370e7d7b4f732f0eca73e35 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 2 117 1.7E-39 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1022 483fd3988f602953ced30685f4d20e92 285 SUPERFAMILY SSF52151 17 267 1.96E-44 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFE_1022 483fd3988f602953ced30685f4d20e92 285 Pfam PF01734 Patatin-like phospholipase 20 181 2.0E-21 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFE_1022 483fd3988f602953ced30685f4d20e92 285 Gene3D G3DSA:3.40.1090.10 1 120 1.5E-22 T 12-10-2018 AFE_1664 ee034e93ac8ad470bcccd377fa26565b 370 SUPERFAMILY SSF55103 197 368 2.35E-20 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFE_1664 ee034e93ac8ad470bcccd377fa26565b 370 SUPERFAMILY SSF56176 21 187 3.92E-36 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFE_1664 ee034e93ac8ad470bcccd377fa26565b 370 Pfam PF01565 FAD binding domain 19 149 5.5E-24 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFE_1664 ee034e93ac8ad470bcccd377fa26565b 370 Gene3D G3DSA:3.30.465.10 67 186 1.3E-34 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFE_3054 04ef0dff4806087407a9a00e794034a7 772 SMART SM00327 580 761 5.2E-11 T 12-10-2018 IPR002035 von Willebrand factor, type A AFE_3054 04ef0dff4806087407a9a00e794034a7 772 Gene3D G3DSA:3.40.50.410 577 757 1.1E-13 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_3054 04ef0dff4806087407a9a00e794034a7 772 SUPERFAMILY SSF53300 582 764 2.67E-19 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_3054 04ef0dff4806087407a9a00e794034a7 772 Pfam PF00092 von Willebrand factor type A domain 584 739 4.1E-6 T 12-10-2018 IPR002035 von Willebrand factor, type A AFE_1653 5e0c42592fa9b299632c9e5096729ec0 89 Gene3D G3DSA:1.10.10.10 4 89 3.2E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1653 5e0c42592fa9b299632c9e5096729ec0 89 SUPERFAMILY SSF46785 12 87 7.43E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_3002 fdeeddf746794254a23c55a025333593 231 SUPERFAMILY SSF74653 161 227 1.44E-7 T 12-10-2018 AFE_3002 fdeeddf746794254a23c55a025333593 231 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 162 228 2.2E-11 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 AFE_3002 fdeeddf746794254a23c55a025333593 231 PRINTS PR01217 Proline rich extensin signature 5 17 3.0E-10 T 12-10-2018 AFE_3002 fdeeddf746794254a23c55a025333593 231 PRINTS PR01217 Proline rich extensin signature 110 127 3.0E-10 T 12-10-2018 AFE_3002 fdeeddf746794254a23c55a025333593 231 PRINTS PR01217 Proline rich extensin signature 88 104 3.0E-10 T 12-10-2018 AFE_3002 fdeeddf746794254a23c55a025333593 231 PRINTS PR01217 Proline rich extensin signature 65 86 3.0E-10 T 12-10-2018 AFE_3002 fdeeddf746794254a23c55a025333593 231 Gene3D G3DSA:3.30.1150.10 105 230 1.7E-15 T 12-10-2018 AFE_2969 0e09427d29d0f3f5b7f6ee8155d92cc9 271 Gene3D G3DSA:3.40.50.150 28 231 1.9E-13 T 12-10-2018 AFE_2969 0e09427d29d0f3f5b7f6ee8155d92cc9 271 SUPERFAMILY SSF53335 62 220 7.38E-11 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2969 0e09427d29d0f3f5b7f6ee8155d92cc9 271 Pfam PF13489 Methyltransferase domain 64 194 8.8E-7 T 12-10-2018 AFE_0861 af5bbeedc009830c26c3e8f403858ab4 153 Pfam PF00042 Globin 5 98 9.2E-10 T 12-10-2018 IPR000971 Globin GO:0020037 AFE_0861 af5bbeedc009830c26c3e8f403858ab4 153 Gene3D G3DSA:1.10.490.10 2 138 3.1E-38 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFE_0861 af5bbeedc009830c26c3e8f403858ab4 153 SUPERFAMILY SSF46458 5 130 3.16E-32 T 12-10-2018 IPR009050 Globin-like superfamily AFE_1726 437d43cbc65948d7881166b866217095 181 Pfam PF10502 Signal peptidase, peptidase S26 24 169 5.6E-19 T 12-10-2018 IPR019533 Peptidase S26 AFE_1726 437d43cbc65948d7881166b866217095 181 SUPERFAMILY SSF51306 32 168 1.83E-12 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFE_0398 4ad917e2b7dbc27344b110b67e8a8b96 265 Pfam PF08241 Methyltransferase domain 87 131 4.7E-8 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFE_0398 4ad917e2b7dbc27344b110b67e8a8b96 265 SUPERFAMILY SSF53335 86 206 1.47E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0398 4ad917e2b7dbc27344b110b67e8a8b96 265 Gene3D G3DSA:3.40.50.150 27 205 1.1E-16 T 12-10-2018 AFE_3215 9c377409d35b77801c22616e57c896c6 149 Pfam PF04170 NlpE N-terminal domain 51 134 4.9E-22 T 12-10-2018 IPR007298 Copper resistance lipoprotein NlpE AFE_3215 9c377409d35b77801c22616e57c896c6 149 Gene3D G3DSA:2.40.128.640 38 145 3.5E-29 T 12-10-2018 AFE_0983 fd916226d6cc76d5351562ce23e2a108 562 Gene3D G3DSA:3.40.50.300 340 560 7.7E-69 T 12-10-2018 AFE_0983 fd916226d6cc76d5351562ce23e2a108 562 Gene3D G3DSA:1.20.1560.10 5 330 8.9E-79 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_0983 fd916226d6cc76d5351562ce23e2a108 562 SMART SM00382 366 551 1.5E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0983 fd916226d6cc76d5351562ce23e2a108 562 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_0983 fd916226d6cc76d5351562ce23e2a108 562 Pfam PF00005 ABC transporter 357 505 1.3E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0983 fd916226d6cc76d5351562ce23e2a108 562 SUPERFAMILY SSF52540 353 554 1.01E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0983 fd916226d6cc76d5351562ce23e2a108 562 Pfam PF00664 ABC transporter transmembrane region 31 296 1.0E-40 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFE_0983 fd916226d6cc76d5351562ce23e2a108 562 SUPERFAMILY SSF90123 17 328 1.12E-72 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_2246 28e835bc67519fb1e73d7dc1772e5b4d 201 Gene3D G3DSA:3.40.30.10 53 199 2.8E-25 T 12-10-2018 AFE_2246 28e835bc67519fb1e73d7dc1772e5b4d 201 Pfam PF13098 Thioredoxin-like domain 58 197 5.8E-13 T 12-10-2018 IPR012336 Thioredoxin-like fold AFE_2246 28e835bc67519fb1e73d7dc1772e5b4d 201 SUPERFAMILY SSF52833 56 197 3.98E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_3183 a966693cf5415fc533b096ace2409327 342 Pfam PF02371 Transposase IS116/IS110/IS902 family 212 289 8.0E-24 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 AFE_3183 a966693cf5415fc533b096ace2409327 342 Pfam PF01548 Transposase 8 145 1.0E-11 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 AFE_1895 a966693cf5415fc533b096ace2409327 342 Pfam PF02371 Transposase IS116/IS110/IS902 family 212 289 8.0E-24 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 AFE_1895 a966693cf5415fc533b096ace2409327 342 Pfam PF01548 Transposase 8 145 1.0E-11 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 AFE_0490 13217ee7690960a3765171600158f309 60 Pfam PF03966 Trm112p-like protein 4 42 5.5E-8 T 12-10-2018 IPR005651 Trm112-like AFE_0490 13217ee7690960a3765171600158f309 60 Gene3D G3DSA:2.20.25.10 10 60 4.6E-19 T 12-10-2018 AFE_0490 13217ee7690960a3765171600158f309 60 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 3 56 25.355 T 12-10-2018 IPR038053 Uncharacterised protein family UPF0434 AFE_0490 13217ee7690960a3765171600158f309 60 SUPERFAMILY SSF158997 1 57 1.83E-20 T 12-10-2018 AFE_0186 d9a9bb31495db9766b94d92aa8e0884a 266 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 191 202 2.8E-18 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial AFE_0186 d9a9bb31495db9766b94d92aa8e0884a 266 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 180 190 2.8E-18 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial AFE_0186 d9a9bb31495db9766b94d92aa8e0884a 266 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 203 218 2.8E-18 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial AFE_0186 d9a9bb31495db9766b94d92aa8e0884a 266 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 117 134 2.8E-18 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial AFE_0186 d9a9bb31495db9766b94d92aa8e0884a 266 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 15 97 1.5E-35 T 12-10-2018 IPR010627 Peptidase A24A, N-terminal AFE_0186 d9a9bb31495db9766b94d92aa8e0884a 266 Pfam PF01478 Type IV leader peptidase family 108 222 1.6E-21 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 AFE_2210 80970b14436950eac7c9aac9c10f09dd 242 Gene3D G3DSA:3.40.50.1820 12 237 2.3E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_2210 80970b14436950eac7c9aac9c10f09dd 242 Pfam PF01738 Dienelactone hydrolase family 17 237 6.1E-49 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 AFE_2210 80970b14436950eac7c9aac9c10f09dd 242 SUPERFAMILY SSF53474 16 239 1.46E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_2889 f2a46838518b55321230259fbe2d61a7 77 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 37 3.4E-13 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_2889 f2a46838518b55321230259fbe2d61a7 77 SUPERFAMILY SSF89447 1 72 2.96E-13 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFE_2889 f2a46838518b55321230259fbe2d61a7 77 SMART SM00966 4 50 1.4E-9 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_2889 f2a46838518b55321230259fbe2d61a7 77 Gene3D G3DSA:2.10.260.10 1 38 6.1E-13 T 12-10-2018 AFE_0547 c2653567a5967fd7038095442793e615 307 Gene3D G3DSA:3.20.10.10 130 295 1.2E-55 T 12-10-2018 AFE_0547 c2653567a5967fd7038095442793e615 307 Pfam PF01063 Amino-transferase class IV 36 267 2.4E-54 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 AFE_0547 c2653567a5967fd7038095442793e615 307 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 11 306 3.0E-134 T 12-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 AFE_0547 c2653567a5967fd7038095442793e615 307 ProSitePatterns PS00770 Aminotransferases class-IV signature. 194 222 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 AFE_0547 c2653567a5967fd7038095442793e615 307 SUPERFAMILY SSF56752 1 303 1.57E-104 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 AFE_0547 c2653567a5967fd7038095442793e615 307 Gene3D G3DSA:3.30.470.10 2 129 4.5E-40 T 12-10-2018 AFE_2364 6d6fc4b5d80bc0a407a7f499b31ee1f4 141 SMART SM00450 41 138 2.1E-26 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_2364 6d6fc4b5d80bc0a407a7f499b31ee1f4 141 Gene3D G3DSA:3.40.250.10 25 141 2.1E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_2364 6d6fc4b5d80bc0a407a7f499b31ee1f4 141 Pfam PF00581 Rhodanese-like domain 43 134 9.0E-20 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_2364 6d6fc4b5d80bc0a407a7f499b31ee1f4 141 SUPERFAMILY SSF52821 20 141 2.75E-37 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_0927 a2ce18bad50af6a52b5ad5c3f27399a1 296 SUPERFAMILY SSF52374 7 273 4.02E-69 T 12-10-2018 AFE_0927 a2ce18bad50af6a52b5ad5c3f27399a1 296 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 7 234 1.5E-32 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 AFE_0927 a2ce18bad50af6a52b5ad5c3f27399a1 296 Gene3D G3DSA:3.40.50.620 9 275 1.1E-82 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0927 a2ce18bad50af6a52b5ad5c3f27399a1 296 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 8 269 1.3E-95 T 12-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 AFE_0927 a2ce18bad50af6a52b5ad5c3f27399a1 296 PRINTS PR00987 Glutamyl-tRNA synthetase signature 186 194 5.5E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_0927 a2ce18bad50af6a52b5ad5c3f27399a1 296 PRINTS PR00987 Glutamyl-tRNA synthetase signature 10 22 5.5E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_0927 a2ce18bad50af6a52b5ad5c3f27399a1 296 PRINTS PR00987 Glutamyl-tRNA synthetase signature 39 52 5.5E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_0927 a2ce18bad50af6a52b5ad5c3f27399a1 296 PRINTS PR00987 Glutamyl-tRNA synthetase signature 24 35 5.5E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_0927 a2ce18bad50af6a52b5ad5c3f27399a1 296 PRINTS PR00987 Glutamyl-tRNA synthetase signature 170 180 5.5E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFE_0927 a2ce18bad50af6a52b5ad5c3f27399a1 296 Gene3D G3DSA:3.40.50.620 82 218 1.1E-82 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0101 7d2560610982e337154073321aad806d 230 SMART SM00382 31 219 2.9E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0101 7d2560610982e337154073321aad806d 230 Gene3D G3DSA:3.40.50.300 1 229 1.7E-66 T 12-10-2018 AFE_0101 7d2560610982e337154073321aad806d 230 Pfam PF00005 ABC transporter 22 171 6.3E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0101 7d2560610982e337154073321aad806d 230 SUPERFAMILY SSF52540 2 224 2.3E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0101 7d2560610982e337154073321aad806d 230 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 ProSitePatterns PS01242 Zinc finger FPG-type signature. 245 269 - T 12-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 115 9.1E-32 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 SMART SM01232 130 222 1.0E-45 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 269 8.0E-88 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 SUPERFAMILY SSF46946 131 222 4.86E-28 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 SUPERFAMILY SSF81624 2 135 6.67E-42 T 12-10-2018 IPR035937 MutM-like, N-terminal AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 130 219 7.2E-23 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 Pfam PF06827 Zinc finger found in FPG and IleRS 242 269 1.1E-5 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 Gene3D G3DSA:3.20.190.10 2 129 1.2E-39 T 12-10-2018 IPR035937 MutM-like, N-terminal AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 Gene3D G3DSA:1.10.8.50 140 270 9.6E-43 T 12-10-2018 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 SMART SM00898 2 116 1.1E-49 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 270 43.398 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 AFE_2758 3c76bb4dace9a0e4eccfb7e3a64e62c7 270 SUPERFAMILY SSF57716 218 269 2.85E-15 T 12-10-2018 AFE_2917 b4afdc0ee912f6666d347254d7335c4b 237 SUPERFAMILY SSF52317 17 193 2.5E-47 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_2917 b4afdc0ee912f6666d347254d7335c4b 237 Pfam PF00117 Glutamine amidotransferase class-I 18 185 8.5E-15 T 12-10-2018 IPR017926 Glutamine amidotransferase AFE_2917 b4afdc0ee912f6666d347254d7335c4b 237 Gene3D G3DSA:3.40.50.880 1 234 2.6E-64 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_1217 53a701a41bbfc139c2cfa3e992bb5a61 203 SUPERFAMILY SSF52141 3 178 2.78E-34 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_1217 53a701a41bbfc139c2cfa3e992bb5a61 203 Gene3D G3DSA:3.40.470.10 1 192 4.6E-42 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_1217 53a701a41bbfc139c2cfa3e992bb5a61 203 SMART SM00986 22 192 1.4E-18 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_1217 53a701a41bbfc139c2cfa3e992bb5a61 203 SMART SM00987 22 192 1.4E-18 T 12-10-2018 AFE_1217 53a701a41bbfc139c2cfa3e992bb5a61 203 Pfam PF03167 Uracil DNA glycosylase superfamily 29 177 1.9E-28 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_2178 9651208b81a92ccf95c38e3fbe07545c 207 Gene3D G3DSA:3.30.70.20 1 206 9.0E-59 T 12-10-2018 AFE_2178 9651208b81a92ccf95c38e3fbe07545c 207 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 93 104 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_2178 9651208b81a92ccf95c38e3fbe07545c 207 SUPERFAMILY SSF54862 1 200 2.09E-64 T 12-10-2018 AFE_2178 9651208b81a92ccf95c38e3fbe07545c 207 Pfam PF13247 4Fe-4S dicluster domain 55 111 7.5E-13 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_2178 9651208b81a92ccf95c38e3fbe07545c 207 Pfam PF13247 4Fe-4S dicluster domain 129 166 5.2E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_2877 91239817d362838409b543f74d4a8d42 703 Pfam PF00069 Protein kinase domain 14 220 6.7E-7 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFE_2877 91239817d362838409b543f74d4a8d42 703 SUPERFAMILY SSF56112 10 245 2.23E-17 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFE_2877 91239817d362838409b543f74d4a8d42 703 Gene3D G3DSA:1.10.510.10 83 294 4.2E-12 T 12-10-2018 AFE_1640 01f9c78f8e45f4d9388c77f940c6dd15 246 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 1 245 2.0E-74 T 12-10-2018 IPR014147 Type IV conjugative transfer protein TrbJ AFE_0893 ebf5b03104c7664517dca303537db513 350 Gene3D G3DSA:1.20.120.420 2 145 4.3E-43 T 12-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFE_0893 ebf5b03104c7664517dca303537db513 350 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 35 333 7.8E-115 T 12-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFE_0893 ebf5b03104c7664517dca303537db513 350 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 8 333 5.7E-136 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFE_0893 ebf5b03104c7664517dca303537db513 350 Pfam PF01008 Initiation factor 2 subunit family 49 334 5.6E-81 T 12-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 AFE_0893 ebf5b03104c7664517dca303537db513 350 SUPERFAMILY SSF100950 5 336 4.26E-119 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFE_0893 ebf5b03104c7664517dca303537db513 350 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 6 344 40.419 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFE_0893 ebf5b03104c7664517dca303537db513 350 Gene3D G3DSA:3.40.50.10470 151 345 7.5E-67 T 12-10-2018 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 Gene3D G3DSA:3.40.50.720 6 259 1.4E-102 T 12-10-2018 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 36.819 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 SUPERFAMILY SSF51735 123 282 1.58E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 121 1.8E-35 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 SUPERFAMILY SSF53223 3 122 5.66E-35 T 12-10-2018 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 4.4E-67 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 Gene3D G3DSA:3.40.50.10860 8 276 1.4E-102 T 12-10-2018 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 2.6E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 2.6E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 2.6E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 2.6E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 2.6E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 2.6E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 2.6E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1877 8eb7e7f664df8ddf3bbd9a20354ca8e4 288 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 260 268 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFE_1403 5b5840e25605beaf8eb1a73a67309a93 241 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 4 237 2.9E-93 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AFE_1403 5b5840e25605beaf8eb1a73a67309a93 241 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 241 124.547 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AFE_1403 5b5840e25605beaf8eb1a73a67309a93 241 SUPERFAMILY SSF63892 1 239 4.84E-95 T 12-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AFE_1403 5b5840e25605beaf8eb1a73a67309a93 241 Gene3D G3DSA:3.20.20.70 1 241 8.6E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_1403 5b5840e25605beaf8eb1a73a67309a93 241 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 4 236 2.7E-100 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 AFE_0371 a5fbe58da04fd6a16d396da6548f5f5b 157 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 155 1.8E-68 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFE_0371 a5fbe58da04fd6a16d396da6548f5f5b 157 SUPERFAMILY SSF69765 1 156 1.44E-65 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFE_0371 a5fbe58da04fd6a16d396da6548f5f5b 157 Gene3D G3DSA:3.30.1330.50 1 157 9.3E-69 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFE_0371 a5fbe58da04fd6a16d396da6548f5f5b 157 Pfam PF02542 YgbB family 1 155 1.1E-65 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFE_0371 a5fbe58da04fd6a16d396da6548f5f5b 157 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFE_0371 a5fbe58da04fd6a16d396da6548f5f5b 157 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 36.601 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 Gene3D G3DSA:3.40.50.10490 10 220 7.8E-91 T 12-10-2018 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 159 183 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 3 226 42.184 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 Pfam PF00318 Ribosomal protein S2 10 225 1.3E-94 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 PRINTS PR00395 Ribosomal protein S2 signature 88 105 4.2E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 PRINTS PR00395 Ribosomal protein S2 signature 159 176 4.2E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 PRINTS PR00395 Ribosomal protein S2 signature 197 211 4.2E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 PRINTS PR00395 Ribosomal protein S2 signature 38 47 4.2E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 PRINTS PR00395 Ribosomal protein S2 signature 7 25 4.2E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 PRINTS PR00395 Ribosomal protein S2 signature 176 187 4.2E-35 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 7 18 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 5 227 2.7E-102 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 SUPERFAMILY SSF52313 7 228 7.46E-94 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily AFE_1444 9ea8c6ef105a45a89d4d50e3f3abb164 250 Gene3D G3DSA:1.10.287.610 104 151 7.8E-91 T 12-10-2018 AFE_2741 4773d24d6c1a0c5ceefcb35a41040723 404 Pfam PF07396 Phosphate-selective porin O and P 53 371 3.7E-8 T 12-10-2018 IPR010870 Phosphate-selective porin O/P AFE_2741 4773d24d6c1a0c5ceefcb35a41040723 404 SUPERFAMILY SSF56935 58 362 1.41E-6 T 12-10-2018 AFE_2741 4773d24d6c1a0c5ceefcb35a41040723 404 Gene3D G3DSA:2.40.160.10 29 311 9.5E-11 T 12-10-2018 IPR023614 Porin domain superfamily AFE_2079 91d56c3c3f8e13e41eb95b7a988cc767 213 SUPERFAMILY SSF56024 66 207 3.81E-31 T 12-10-2018 AFE_2079 91d56c3c3f8e13e41eb95b7a988cc767 213 Gene3D G3DSA:3.30.870.10 59 209 3.5E-36 T 12-10-2018 AFE_2079 91d56c3c3f8e13e41eb95b7a988cc767 213 Pfam PF13091 PLD-like domain 76 195 4.8E-24 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFE_2885 c46b3be288d4e33e1a26f3eaa27864bd 127 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 10 119 1.8E-19 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 AFE_2885 c46b3be288d4e33e1a26f3eaa27864bd 127 Gene3D G3DSA:2.30.30.110 4 126 1.1E-28 T 12-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor AFE_2885 c46b3be288d4e33e1a26f3eaa27864bd 127 SUPERFAMILY SSF50118 5 120 6.76E-24 T 12-10-2018 AFE_3230 908b463cbba22d221224ad2d53932c2a 931 Gene3D G3DSA:2.130.10.10 123 291 2.1E-18 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_3230 908b463cbba22d221224ad2d53932c2a 931 Gene3D G3DSA:2.130.10.10 292 410 2.3E-9 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFE_3230 908b463cbba22d221224ad2d53932c2a 931 Pfam PF04185 Phosphoesterase family 710 791 5.0E-7 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 AFE_3230 908b463cbba22d221224ad2d53932c2a 931 SUPERFAMILY SSF50974 90 396 3.4E-28 T 12-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 AFE_3230 908b463cbba22d221224ad2d53932c2a 931 SUPERFAMILY SSF53649 509 795 3.14E-6 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFE_3230 908b463cbba22d221224ad2d53932c2a 931 Gene3D G3DSA:3.40.720.10 493 819 1.7E-9 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_0654 bc75fcc5a56dcc537de71cec7d13be2a 835 Pfam PF12704 MacB-like periplasmic core domain 22 221 5.0E-7 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFE_0654 bc75fcc5a56dcc537de71cec7d13be2a 835 Pfam PF02687 FtsX-like permease family 282 379 5.1E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFE_0654 bc75fcc5a56dcc537de71cec7d13be2a 835 Pfam PF02687 FtsX-like permease family 734 826 6.9E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFE_0396 df94992bee8cee9f497c26d182937fb2 424 SUPERFAMILY SSF63411 242 412 7.83E-34 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFE_0396 df94992bee8cee9f497c26d182937fb2 424 Gene3D G3DSA:3.30.830.10 22 229 2.9E-56 T 12-10-2018 AFE_0396 df94992bee8cee9f497c26d182937fb2 424 Pfam PF05193 Peptidase M16 inactive domain 184 355 9.3E-25 T 12-10-2018 IPR007863 Peptidase M16, C-terminal AFE_0396 df94992bee8cee9f497c26d182937fb2 424 SUPERFAMILY SSF63411 19 227 4.54E-50 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFE_0396 df94992bee8cee9f497c26d182937fb2 424 Gene3D G3DSA:3.30.830.10 240 420 1.1E-39 T 12-10-2018 AFE_0396 df94992bee8cee9f497c26d182937fb2 424 Pfam PF00675 Insulinase (Peptidase family M16) 31 175 3.5E-30 T 12-10-2018 IPR011765 Peptidase M16, N-terminal AFE_0396 df94992bee8cee9f497c26d182937fb2 424 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 51 74 - T 12-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SUPERFAMILY SSF50249 264 366 1.34E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SUPERFAMILY SSF50249 351 450 6.42E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 13 522 3.7E-200 T 12-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Gene3D G3DSA:2.40.50.140 14 107 1.1E-17 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Gene3D G3DSA:2.40.50.140 455 533 7.6E-12 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Gene3D G3DSA:2.40.50.140 196 277 1.4E-26 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SUPERFAMILY SSF50249 13 120 1.34E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Gene3D G3DSA:2.40.50.140 108 188 5.9E-6 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 PRINTS PR00681 Ribosomal protein S1 signature 339 357 1.7E-87 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 PRINTS PR00681 Ribosomal protein S1 signature 164 184 1.7E-87 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 PRINTS PR00681 Ribosomal protein S1 signature 135 152 1.7E-87 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 PRINTS PR00681 Ribosomal protein S1 signature 48 62 1.7E-87 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 PRINTS PR00681 Ribosomal protein S1 signature 93 112 1.7E-87 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 PRINTS PR00681 Ribosomal protein S1 signature 117 133 1.7E-87 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 PRINTS PR00681 Ribosomal protein S1 signature 221 242 1.7E-87 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 PRINTS PR00681 Ribosomal protein S1 signature 30 48 1.7E-87 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 PRINTS PR00681 Ribosomal protein S1 signature 299 318 1.7E-87 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SUPERFAMILY SSF50249 199 284 5.35E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SMART SM00316 458 523 7.0E-11 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SMART SM00316 199 269 5.6E-26 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SMART SM00316 371 443 3.2E-23 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SMART SM00316 284 356 2.1E-25 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SMART SM00316 28 96 1.8E-7 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SMART SM00316 112 180 3.2E-6 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SUPERFAMILY SSF50249 443 528 9.29E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Gene3D G3DSA:2.40.50.140 278 365 1.1E-27 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Gene3D G3DSA:2.40.50.140 366 454 6.3E-25 T 12-10-2018 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 SUPERFAMILY SSF50249 114 190 2.11E-11 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 PIRSF PIRSF002111 1 537 2.1E-204 T 12-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Pfam PF00575 S1 RNA binding domain 458 523 6.9E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Pfam PF00575 S1 RNA binding domain 370 443 2.9E-19 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Pfam PF00575 S1 RNA binding domain 199 269 6.4E-21 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Pfam PF00575 S1 RNA binding domain 28 95 2.5E-7 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Pfam PF00575 S1 RNA binding domain 287 356 1.7E-21 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_0903 c25f39e4964b0dc41d7f6d8489ddcde5 568 Pfam PF00575 S1 RNA binding domain 112 180 1.5E-9 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_1955 0e568b1792951277fb33c645b3029436 131 Gene3D G3DSA:1.10.10.10 1 78 1.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1955 0e568b1792951277fb33c645b3029436 131 Pfam PF01475 Ferric uptake regulator family 8 100 3.9E-16 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFE_1955 0e568b1792951277fb33c645b3029436 131 SUPERFAMILY SSF46785 2 102 8.84E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2527 82d72c52c1c1ef2d9bbacbed4c7bbdcd 215 Pfam PF09335 SNARE associated Golgi protein 49 171 5.2E-18 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFE_1136 97ab093e410e0e9dfb7d73360e8fcee7 176 Pfam PF09335 SNARE associated Golgi protein 43 163 2.6E-17 T 12-10-2018 IPR032816 SNARE associated Golgi protein AFE_0155 0ce68995547e75774f8374561af6375e 201 PIRSF PIRSF000709 1 176 8.1E-11 T 12-10-2018 AFE_0155 0ce68995547e75774f8374561af6375e 201 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 188 1.2E-45 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFE_0155 0ce68995547e75774f8374561af6375e 201 SMART SM00855 5 150 6.3E-16 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFE_0155 0ce68995547e75774f8374561af6375e 201 Gene3D G3DSA:3.40.50.1240 2 192 1.4E-48 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFE_0155 0ce68995547e75774f8374561af6375e 201 SUPERFAMILY SSF53254 6 193 6.0E-45 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFE_0244 b688121d18858d33c52d1cbb2d5ee169 254 Gene3D G3DSA:3.40.50.1820 3 251 3.2E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_0244 b688121d18858d33c52d1cbb2d5ee169 254 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 11 250 3.2E-62 T 12-10-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 AFE_0244 b688121d18858d33c52d1cbb2d5ee169 254 SUPERFAMILY SSF53474 3 251 1.32E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_0244 b688121d18858d33c52d1cbb2d5ee169 254 Pfam PF12697 Alpha/beta hydrolase family 14 247 2.4E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFE_0244 b688121d18858d33c52d1cbb2d5ee169 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 9.9E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFE_0244 b688121d18858d33c52d1cbb2d5ee169 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 9.9E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFE_0244 b688121d18858d33c52d1cbb2d5ee169 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 9.9E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFE_0244 b688121d18858d33c52d1cbb2d5ee169 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 80 93 9.9E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFE_2547 35efb64b6e85ece2a79661c43cdf22e0 145 Pfam PF01597 Glycine cleavage H-protein 15 127 1.2E-37 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate AFE_2547 35efb64b6e85ece2a79661c43cdf22e0 145 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 55 84 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFE_2547 35efb64b6e85ece2a79661c43cdf22e0 145 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 138 31.376 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AFE_2547 35efb64b6e85ece2a79661c43cdf22e0 145 Gene3D G3DSA:2.40.50.100 7 135 7.6E-35 T 12-10-2018 AFE_2547 35efb64b6e85ece2a79661c43cdf22e0 145 SUPERFAMILY SSF51230 14 117 1.96E-28 T 12-10-2018 IPR011053 Single hybrid motif AFE_3170 59675bca0bb7cd6619df1a5f8c4e5683 155 Gene3D G3DSA:3.30.530.20 1 139 7.6E-25 T 12-10-2018 IPR023393 START-like domain superfamily AFE_3170 59675bca0bb7cd6619df1a5f8c4e5683 155 SUPERFAMILY SSF55961 2 138 5.5E-24 T 12-10-2018 AFE_3170 59675bca0bb7cd6619df1a5f8c4e5683 155 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 138 4.1E-12 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFE_0609 2b6ce34d5ea4e6673f2b8f9bd5ea621c 337 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 236 5.3E-60 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFE_0609 2b6ce34d5ea4e6673f2b8f9bd5ea621c 337 Gene3D G3DSA:3.40.50.720 6 317 4.5E-97 T 12-10-2018 AFE_0609 2b6ce34d5ea4e6673f2b8f9bd5ea621c 337 Gene3D G3DSA:3.90.25.10 182 329 4.5E-97 T 12-10-2018 AFE_0609 2b6ce34d5ea4e6673f2b8f9bd5ea621c 337 PRINTS PR01713 Nucleotide sugar epimerase signature 218 233 2.6E-28 T 12-10-2018 AFE_0609 2b6ce34d5ea4e6673f2b8f9bd5ea621c 337 PRINTS PR01713 Nucleotide sugar epimerase signature 257 272 2.6E-28 T 12-10-2018 AFE_0609 2b6ce34d5ea4e6673f2b8f9bd5ea621c 337 PRINTS PR01713 Nucleotide sugar epimerase signature 296 313 2.6E-28 T 12-10-2018 AFE_0609 2b6ce34d5ea4e6673f2b8f9bd5ea621c 337 PRINTS PR01713 Nucleotide sugar epimerase signature 31 47 2.6E-28 T 12-10-2018 AFE_0609 2b6ce34d5ea4e6673f2b8f9bd5ea621c 337 SUPERFAMILY SSF51735 1 334 1.49E-92 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0817 fad919828b1f102d524471627d53251c 296 SUPERFAMILY SSF53850 90 291 1.9E-32 T 12-10-2018 AFE_0817 fad919828b1f102d524471627d53251c 296 Gene3D G3DSA:1.10.10.10 1 90 1.3E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0817 fad919828b1f102d524471627d53251c 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 8.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_0817 fad919828b1f102d524471627d53251c 296 Gene3D G3DSA:3.40.190.10 166 266 1.9E-34 T 12-10-2018 AFE_0817 fad919828b1f102d524471627d53251c 296 Gene3D G3DSA:3.40.190.10 91 288 1.9E-34 T 12-10-2018 AFE_0817 fad919828b1f102d524471627d53251c 296 Pfam PF03466 LysR substrate binding domain 89 290 9.9E-35 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_0817 fad919828b1f102d524471627d53251c 296 SUPERFAMILY SSF46785 1 111 2.12E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0692 28229b852ce9e2c3ef85583f80ae49b8 758 SUPERFAMILY SSF50692 635 752 4.97E-17 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFE_0692 28229b852ce9e2c3ef85583f80ae49b8 758 Gene3D G3DSA:2.40.40.20 636 757 2.5E-5 T 12-10-2018 AFE_0692 28229b852ce9e2c3ef85583f80ae49b8 758 Gene3D G3DSA:3.40.228.10 181 393 2.1E-71 T 12-10-2018 AFE_0692 28229b852ce9e2c3ef85583f80ae49b8 758 PIRSF PIRSF000144 1 754 0.0 T 12-10-2018 AFE_0692 28229b852ce9e2c3ef85583f80ae49b8 758 SUPERFAMILY SSF53706 47 619 2.88E-145 T 12-10-2018 AFE_0692 28229b852ce9e2c3ef85583f80ae49b8 758 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 13 749 1.1E-280 T 12-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 AFE_0692 28229b852ce9e2c3ef85583f80ae49b8 758 Pfam PF01568 Molydopterin dinucleotide binding domain 637 743 2.9E-10 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFE_0692 28229b852ce9e2c3ef85583f80ae49b8 758 Pfam PF00384 Molybdopterin oxidoreductase 109 480 9.2E-32 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_0692 28229b852ce9e2c3ef85583f80ae49b8 758 Gene3D G3DSA:3.40.50.740 120 484 2.1E-71 T 12-10-2018 AFE_0755 6fced5a8ab75a20bcdffc1bf4a8a06ed 322 Gene3D G3DSA:1.10.490.10 4 139 1.0E-12 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFE_0755 6fced5a8ab75a20bcdffc1bf4a8a06ed 322 SUPERFAMILY SSF55781 176 318 3.53E-5 T 12-10-2018 AFE_0755 6fced5a8ab75a20bcdffc1bf4a8a06ed 322 SUPERFAMILY SSF46458 6 122 2.59E-6 T 12-10-2018 IPR009050 Globin-like superfamily AFE_0755 6fced5a8ab75a20bcdffc1bf4a8a06ed 322 Pfam PF11563 Protoglobin 5 123 4.3E-7 T 12-10-2018 AFE_0227 02df1e4dae8ec693b81baa00906debfe 329 TIGRFAM TIGR00586 mutt: mutator mutT protein 5 122 7.2E-30 T 12-10-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 AFE_0227 02df1e4dae8ec693b81baa00906debfe 329 Gene3D G3DSA:3.20.20.70 128 328 1.4E-40 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_0227 02df1e4dae8ec693b81baa00906debfe 329 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFE_0227 02df1e4dae8ec693b81baa00906debfe 329 Pfam PF00293 NUDIX domain 6 110 2.2E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFE_0227 02df1e4dae8ec693b81baa00906debfe 329 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.7E-9 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFE_0227 02df1e4dae8ec693b81baa00906debfe 329 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.7E-9 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFE_0227 02df1e4dae8ec693b81baa00906debfe 329 Pfam PF02581 Thiamine monophosphate synthase 136 310 7.5E-27 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFE_0227 02df1e4dae8ec693b81baa00906debfe 329 SUPERFAMILY SSF55811 3 129 6.91E-34 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFE_0227 02df1e4dae8ec693b81baa00906debfe 329 Gene3D G3DSA:3.90.79.10 1 126 1.2E-36 T 12-10-2018 AFE_0227 02df1e4dae8ec693b81baa00906debfe 329 SUPERFAMILY SSF51391 131 328 5.23E-40 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFE_1569 692422337dd696180fe934e03d74852d 164 Gene3D G3DSA:2.40.50.140 1 122 6.0E-47 T 12-10-2018 AFE_1569 692422337dd696180fe934e03d74852d 164 SUPERFAMILY SSF50249 3 145 1.61E-55 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1569 692422337dd696180fe934e03d74852d 164 Hamap MF_00984 Single-stranded DNA-binding protein. 4 111 36.38 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFE_1569 692422337dd696180fe934e03d74852d 164 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 112 1.8E-49 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFE_1569 692422337dd696180fe934e03d74852d 164 Pfam PF00436 Single-strand binding protein family 4 106 3.1E-40 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AFE_2333 cd9d41ece450920d295ea3d127e8ffeb 438 ProSitePatterns PS00216 Sugar transport proteins signature 1. 85 101 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFE_2333 cd9d41ece450920d295ea3d127e8ffeb 438 SUPERFAMILY SSF103473 17 406 6.8E-62 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_2333 cd9d41ece450920d295ea3d127e8ffeb 438 Pfam PF07690 Major Facilitator Superfamily 261 410 2.4E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_2333 cd9d41ece450920d295ea3d127e8ffeb 438 Pfam PF07690 Major Facilitator Superfamily 35 257 3.2E-27 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_2333 cd9d41ece450920d295ea3d127e8ffeb 438 Gene3D G3DSA:1.20.1250.20 25 408 4.0E-51 T 12-10-2018 AFE_0676 9a78cb07b1fd8525417a5579852d6a03 181 Gene3D G3DSA:1.10.287.110 1 80 6.1E-19 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFE_0676 9a78cb07b1fd8525417a5579852d6a03 181 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 20 178 2.6E-24 T 12-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AFE_0676 9a78cb07b1fd8525417a5579852d6a03 181 Gene3D G3DSA:1.20.1280.20 88 179 2.0E-17 T 12-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AFE_0676 9a78cb07b1fd8525417a5579852d6a03 181 Pfam PF07743 HSCB C-terminal oligomerisation domain 95 172 2.5E-12 T 12-10-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AFE_0676 9a78cb07b1fd8525417a5579852d6a03 181 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 8 179 18.365 T 12-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AFE_0676 9a78cb07b1fd8525417a5579852d6a03 181 SUPERFAMILY SSF47144 84 178 4.84E-15 T 12-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 AFE_0676 9a78cb07b1fd8525417a5579852d6a03 181 SUPERFAMILY SSF46565 9 80 6.28E-13 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFE_1496 5dea9b02c3a45cf6a6ab80c51731d870 400 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 18 292 3.2E-47 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFE_1496 5dea9b02c3a45cf6a6ab80c51731d870 400 Gene3D G3DSA:1.20.1510.10 17 212 7.1E-30 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFE_1496 5dea9b02c3a45cf6a6ab80c51731d870 400 Pfam PF01545 Cation efflux family 22 212 1.2E-31 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFE_1496 5dea9b02c3a45cf6a6ab80c51731d870 400 SUPERFAMILY SSF161111 16 213 1.44E-30 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFE_1496 5dea9b02c3a45cf6a6ab80c51731d870 400 Gene3D G3DSA:3.30.70.1350 213 293 1.8E-11 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFE_1496 5dea9b02c3a45cf6a6ab80c51731d870 400 Pfam PF16916 Dimerisation domain of Zinc Transporter 218 292 3.0E-13 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain AFE_1496 5dea9b02c3a45cf6a6ab80c51731d870 400 SUPERFAMILY SSF160240 216 292 8.5E-13 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFE_2608 4ed09bbe549899460506c1051cd8a4f5 99 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 27.607 T 12-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 AFE_2608 4ed09bbe549899460506c1051cd8a4f5 99 SUPERFAMILY SSF47729 3 94 2.8E-31 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_2608 4ed09bbe549899460506c1051cd8a4f5 99 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AFE_2608 4ed09bbe549899460506c1051cd8a4f5 99 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 93 2.2E-39 T 12-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 AFE_2608 4ed09bbe549899460506c1051cd8a4f5 99 Gene3D G3DSA:4.10.520.10 1 98 3.3E-34 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFE_2608 4ed09bbe549899460506c1051cd8a4f5 99 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 5.1E-13 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_2608 4ed09bbe549899460506c1051cd8a4f5 99 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 5.1E-13 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_2608 4ed09bbe549899460506c1051cd8a4f5 99 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 5.1E-13 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_2608 4ed09bbe549899460506c1051cd8a4f5 99 Pfam PF00216 Bacterial DNA-binding protein 3 92 3.4E-30 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_2608 4ed09bbe549899460506c1051cd8a4f5 99 SMART SM00411 3 92 4.0E-37 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFE_1353 33108058093d10ad413fe6125eb52ec3 632 SUPERFAMILY SSF52402 231 607 1.07E-71 T 12-10-2018 AFE_1353 33108058093d10ad413fe6125eb52ec3 632 SUPERFAMILY SSF56235 1 223 1.63E-57 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_1353 33108058093d10ad413fe6125eb52ec3 632 Pfam PF00733 Asparagine synthase 240 613 3.3E-81 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 AFE_1353 33108058093d10ad413fe6125eb52ec3 632 PIRSF PIRSF001589 1 628 5.2E-153 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 AFE_1353 33108058093d10ad413fe6125eb52ec3 632 Gene3D G3DSA:3.60.20.10 4 185 7.5E-58 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_1353 33108058093d10ad413fe6125eb52ec3 632 Pfam PF13537 Glutamine amidotransferase domain 47 165 2.1E-41 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFE_1353 33108058093d10ad413fe6125eb52ec3 632 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 549 3.0E-128 T 12-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 AFE_2118 fa64fd2bf57f59a4ebf084ad1f179c56 879 TIGRFAM TIGR03480 HpnN: hopanoid biosynthesis associated RND transporter like protein HpnN 2 861 0.0 T 12-10-2018 IPR017841 Hopanoid biosynthesis associated RND transporter-like protein HpnN AFE_2118 fa64fd2bf57f59a4ebf084ad1f179c56 879 SUPERFAMILY SSF82866 689 865 6.67E-25 T 12-10-2018 AFE_2118 fa64fd2bf57f59a4ebf084ad1f179c56 879 SUPERFAMILY SSF82866 237 421 5.1E-23 T 12-10-2018 AFE_2118 fa64fd2bf57f59a4ebf084ad1f179c56 879 Pfam PF03176 MMPL family 226 420 6.6E-20 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFE_2118 fa64fd2bf57f59a4ebf084ad1f179c56 879 Pfam PF03176 MMPL family 700 867 1.1E-8 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFE_2118 fa64fd2bf57f59a4ebf084ad1f179c56 879 Gene3D G3DSA:1.20.1640.10 685 877 6.3E-9 T 12-10-2018 AFE_1956 47faff06b0cc871b73ca362ef8aa9f31 363 SUPERFAMILY SSF54373 215 300 1.57E-18 T 12-10-2018 AFE_1956 47faff06b0cc871b73ca362ef8aa9f31 363 SUPERFAMILY SSF51905 8 356 1.07E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1956 47faff06b0cc871b73ca362ef8aa9f31 363 Gene3D G3DSA:3.50.50.60 10 342 2.7E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1956 47faff06b0cc871b73ca362ef8aa9f31 363 Pfam PF01266 FAD dependent oxidoreductase 10 340 1.5E-63 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFE_1956 47faff06b0cc871b73ca362ef8aa9f31 363 Gene3D G3DSA:3.30.9.10 96 301 2.7E-83 T 12-10-2018 AFE_0786 b3e8968c4f7e94f2d07b67c653851cd4 173 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 96 7.3E-9 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFE_0786 b3e8968c4f7e94f2d07b67c653851cd4 173 Gene3D G3DSA:2.30.110.10 2 166 1.4E-44 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFE_0786 b3e8968c4f7e94f2d07b67c653851cd4 173 PIRSF PIRSF004633 1 166 6.9E-38 T 12-10-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain AFE_0786 b3e8968c4f7e94f2d07b67c653851cd4 173 SUPERFAMILY SSF50475 1 156 8.51E-24 T 12-10-2018 AFE_2184 88d817a4b90b27588424329aae1480ae 514 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 491 2.9E-124 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFE_2184 88d817a4b90b27588424329aae1480ae 514 Gene3D G3DSA:1.20.1720.10 16 223 1.7E-52 T 12-10-2018 AFE_2184 88d817a4b90b27588424329aae1480ae 514 Pfam PF07690 Major Facilitator Superfamily 20 414 3.4E-56 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_2184 88d817a4b90b27588424329aae1480ae 514 SUPERFAMILY SSF103473 10 504 1.7E-68 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_2184 88d817a4b90b27588424329aae1480ae 514 Gene3D G3DSA:1.20.1250.20 272 505 1.4E-12 T 12-10-2018 AFE_2184 88d817a4b90b27588424329aae1480ae 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 19 43 1.9E-5 T 12-10-2018 AFE_2184 88d817a4b90b27588424329aae1480ae 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 1.9E-5 T 12-10-2018 AFE_2184 88d817a4b90b27588424329aae1480ae 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 205 223 1.9E-5 T 12-10-2018 AFE_2184 88d817a4b90b27588424329aae1480ae 514 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 1.9E-5 T 12-10-2018 AFE_3202 3926e52468e5513ba882f662f432f858 141 SUPERFAMILY SSF46604 88 135 3.14E-11 T 12-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3202 3926e52468e5513ba882f662f432f858 141 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 130 21.85 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3202 3926e52468e5513ba882f662f432f858 141 SUPERFAMILY SSF51344 3 85 8.63E-24 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3202 3926e52468e5513ba882f662f432f858 141 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 83 7.8E-29 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3202 3926e52468e5513ba882f662f432f858 141 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 132 7.8E-38 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3202 3926e52468e5513ba882f662f432f858 141 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 131 4.3E-9 T 12-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain AFE_3202 3926e52468e5513ba882f662f432f858 141 Gene3D G3DSA:2.60.15.10 3 89 7.1E-30 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3202 3926e52468e5513ba882f662f432f858 141 Gene3D G3DSA:1.20.5.440 90 132 4.7E-13 T 12-10-2018 AFE_3202 3926e52468e5513ba882f662f432f858 141 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 85 6.0E-37 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_0098 080873f3e641320be7e5046278306eca 752 Gene3D G3DSA:3.50.50.100 325 723 3.2E-118 T 12-10-2018 AFE_0098 080873f3e641320be7e5046278306eca 752 Pfam PF07681 DoxX 61 141 1.0E-9 T 12-10-2018 IPR032808 DoxX family AFE_0098 080873f3e641320be7e5046278306eca 752 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 616 623 1.2E-6 T 12-10-2018 AFE_0098 080873f3e641320be7e5046278306eca 752 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 328 350 1.2E-6 T 12-10-2018 AFE_0098 080873f3e641320be7e5046278306eca 752 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 480 505 1.2E-6 T 12-10-2018 AFE_0098 080873f3e641320be7e5046278306eca 752 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 328 644 1.8E-50 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_0098 080873f3e641320be7e5046278306eca 752 SUPERFAMILY SSF51905 328 658 3.27E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0098 080873f3e641320be7e5046278306eca 752 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 329 348 6.0E-12 T 12-10-2018 AFE_0098 080873f3e641320be7e5046278306eca 752 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 480 498 6.0E-12 T 12-10-2018 AFE_0098 080873f3e641320be7e5046278306eca 752 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 601 623 6.0E-12 T 12-10-2018 AFE_0098 080873f3e641320be7e5046278306eca 752 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 420 438 6.0E-12 T 12-10-2018 AFE_1463 ab90bf7ef7991516683dbf3f5f3c046e 443 Gene3D G3DSA:3.20.20.140 55 402 5.5E-130 T 12-10-2018 AFE_1463 ab90bf7ef7991516683dbf3f5f3c046e 443 ProSitePatterns PS00483 Dihydroorotase signature 2. 298 309 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_1463 ab90bf7ef7991516683dbf3f5f3c046e 443 Pfam PF01979 Amidohydrolase family 50 416 3.2E-28 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFE_1463 ab90bf7ef7991516683dbf3f5f3c046e 443 SUPERFAMILY SSF51556 54 363 3.99E-93 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFE_1463 ab90bf7ef7991516683dbf3f5f3c046e 443 Gene3D G3DSA:2.30.40.10 5 417 5.5E-130 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_1463 ab90bf7ef7991516683dbf3f5f3c046e 443 SUPERFAMILY SSF51338 1 427 4.33E-31 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_1463 ab90bf7ef7991516683dbf3f5f3c046e 443 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 20 418 1.6E-101 T 12-10-2018 AFE_0742 30ceb6b6ebcc5ef25a39d6893a982937 143 PIRSF PIRSF004681 1 139 2.4E-43 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 AFE_0742 30ceb6b6ebcc5ef25a39d6893a982937 143 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 14 138 1.8E-37 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 AFE_0742 30ceb6b6ebcc5ef25a39d6893a982937 143 Pfam PF01894 Uncharacterised protein family UPF0047 19 135 4.8E-35 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 AFE_0742 30ceb6b6ebcc5ef25a39d6893a982937 143 Gene3D G3DSA:2.60.120.460 4 138 3.3E-37 T 12-10-2018 IPR035917 YjbQ-like superfamily AFE_0742 30ceb6b6ebcc5ef25a39d6893a982937 143 SUPERFAMILY SSF111038 7 138 4.45E-41 T 12-10-2018 IPR035917 YjbQ-like superfamily AFE_3020 c8766e87ebfa43c69d8bc654abf01435 138 SUPERFAMILY SSF53062 1 125 3.4E-24 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 AFE_3020 c8766e87ebfa43c69d8bc654abf01435 138 Gene3D G3DSA:3.40.50.510 1 136 3.0E-26 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 AFE_3020 c8766e87ebfa43c69d8bc654abf01435 138 Pfam PF03610 PTS system fructose IIA component 4 105 3.5E-13 T 12-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 AFE_2635 954c121785a4dd8f84d784a90a869f79 277 Pfam PF00809 Pterin binding enzyme 20 261 6.9E-85 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFE_2635 954c121785a4dd8f84d784a90a869f79 277 SUPERFAMILY SSF51717 7 274 3.53E-99 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFE_2635 954c121785a4dd8f84d784a90a869f79 277 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 19 34 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFE_2635 954c121785a4dd8f84d784a90a869f79 277 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 53 66 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFE_2635 954c121785a4dd8f84d784a90a869f79 277 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 19 274 1.5E-96 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 AFE_2635 954c121785a4dd8f84d784a90a869f79 277 Gene3D G3DSA:3.20.20.20 2 277 3.0E-107 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 Gene3D G3DSA:3.30.930.10 105 421 6.2E-119 T 12-10-2018 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 PIRSF PIRSF001529 1 421 2.4E-169 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 SUPERFAMILY SSF46589 1 112 8.89E-26 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 Gene3D G3DSA:1.10.287.40 1 104 1.6E-20 T 12-10-2018 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 418 41.529 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 413 4.8E-160 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 396 9.5E-32 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 SUPERFAMILY SSF55681 116 417 4.35E-98 T 12-10-2018 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 PRINTS PR00981 Seryl-tRNA synthetase signature 261 273 3.6E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 PRINTS PR00981 Seryl-tRNA synthetase signature 330 346 3.6E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 PRINTS PR00981 Seryl-tRNA synthetase signature 348 364 3.6E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 PRINTS PR00981 Seryl-tRNA synthetase signature 313 326 3.6E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 PRINTS PR00981 Seryl-tRNA synthetase signature 273 286 3.6E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFE_0380 79134a7da78fbb0baa9a94150296b768 421 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 3.9E-25 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 AFE_1942 c18b83a7b161fba2257665ee80cb765a 254 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 19 85 3.6E-8 T 12-10-2018 IPR018720 Domain of unknown function DUF2249 AFE_1942 c18b83a7b161fba2257665ee80cb765a 254 Pfam PF01814 Hemerythrin HHE cation binding domain 95 214 1.0E-7 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 AFE_1942 c18b83a7b161fba2257665ee80cb765a 254 Gene3D G3DSA:1.20.120.520 83 227 6.1E-7 T 12-10-2018 AFE_0404 b5043701214d75d3fc4d056591e2890f 399 Pfam PF00764 Arginosuccinate synthase 6 393 4.2E-157 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFE_0404 b5043701214d75d3fc4d056591e2890f 399 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFE_0404 b5043701214d75d3fc4d056591e2890f 399 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 399 53.227 T 12-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFE_0404 b5043701214d75d3fc4d056591e2890f 399 Gene3D G3DSA:3.40.50.620 3 174 6.3E-70 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0404 b5043701214d75d3fc4d056591e2890f 399 Gene3D G3DSA:3.90.1260.10 175 399 6.8E-99 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFE_0404 b5043701214d75d3fc4d056591e2890f 399 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 116 127 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFE_0404 b5043701214d75d3fc4d056591e2890f 399 SUPERFAMILY SSF69864 172 396 1.96E-92 T 12-10-2018 AFE_0404 b5043701214d75d3fc4d056591e2890f 399 SUPERFAMILY SSF52402 3 206 1.04E-50 T 12-10-2018 AFE_0404 b5043701214d75d3fc4d056591e2890f 399 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 394 2.5E-142 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFE_0933 86b9dc7fcde1c462b343f34a6571eead 150 Pfam PF02631 RecX family 32 141 6.4E-23 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 AFE_0933 86b9dc7fcde1c462b343f34a6571eead 150 Gene3D G3DSA:1.10.10.10 94 141 8.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0933 86b9dc7fcde1c462b343f34a6571eead 150 Hamap MF_01114 Regulatory protein RecX [recX]. 2 146 11.481 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 AFE_0933 86b9dc7fcde1c462b343f34a6571eead 150 Gene3D G3DSA:1.10.10.10 6 53 9.2E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0933 86b9dc7fcde1c462b343f34a6571eead 150 Gene3D G3DSA:1.10.10.10 54 89 1.7E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0875 d70492424b19b2056550e7d0fcbdb4b4 158 Gene3D G3DSA:3.40.630.30 1 156 1.1E-23 T 12-10-2018 AFE_0875 d70492424b19b2056550e7d0fcbdb4b4 158 SUPERFAMILY SSF55729 2 156 1.32E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_0875 d70492424b19b2056550e7d0fcbdb4b4 158 Pfam PF13673 Acetyltransferase (GNAT) domain 41 133 6.9E-8 T 12-10-2018 IPR000182 GNAT domain AFE_2211 d81d7ae3635223e8d82c1395427369a3 358 Gene3D G3DSA:3.20.20.70 2 356 3.6E-125 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2211 d81d7ae3635223e8d82c1395427369a3 358 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 338 6.1E-66 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AFE_2211 d81d7ae3635223e8d82c1395427369a3 358 SUPERFAMILY SSF51395 3 352 1.69E-117 T 12-10-2018 AFE_2506 ff671dc86d78a0e1505b49ac301eedfe 229 Pfam PF08721 TnsA endonuclease C terminal 140 213 1.0E-13 T 12-10-2018 IPR014832 TnsA endonuclease C-terminal AFE_2506 ff671dc86d78a0e1505b49ac301eedfe 229 Pfam PF08722 TnsA endonuclease N terminal 55 136 5.0E-13 T 12-10-2018 IPR014833 TnsA endonuclease, N-terminal AFE_2807 34713e8429fcd8621b93d7d3db5c4954 218 Pfam PF04299 Putative FMN-binding domain 2 168 1.1E-56 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type AFE_2807 34713e8429fcd8621b93d7d3db5c4954 218 Gene3D G3DSA:2.30.110.10 1 208 4.6E-67 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFE_2807 34713e8429fcd8621b93d7d3db5c4954 218 PIRSF PIRSF010372 1 210 5.5E-64 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type AFE_2807 34713e8429fcd8621b93d7d3db5c4954 218 SUPERFAMILY SSF50475 11 194 2.81E-33 T 12-10-2018 AFE_0138 d1ad4927c1dba684d9e3328e58fda3b4 369 Gene3D G3DSA:3.40.50.2000 37 184 4.3E-45 T 12-10-2018 AFE_0138 d1ad4927c1dba684d9e3328e58fda3b4 369 SUPERFAMILY SSF53756 38 367 1.22E-88 T 12-10-2018 AFE_0138 d1ad4927c1dba684d9e3328e58fda3b4 369 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 105 349 3.1E-58 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 AFE_0138 d1ad4927c1dba684d9e3328e58fda3b4 369 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 38 366 5.6E-114 T 12-10-2018 IPR011910 ADP-heptose--LPS heptosyltransferase 2 GO:0009103|GO:0016757 AFE_0138 d1ad4927c1dba684d9e3328e58fda3b4 369 Gene3D G3DSA:3.40.50.2000 198 369 4.3E-52 T 12-10-2018 AFE_0646 4b597597fffc0bf3113d6b8a8feced91 283 SMART SM00382 31 221 4.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_0646 4b597597fffc0bf3113d6b8a8feced91 283 SUPERFAMILY SSF52540 7 231 2.76E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0646 4b597597fffc0bf3113d6b8a8feced91 283 Pfam PF00005 ABC transporter 24 172 3.9E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0646 4b597597fffc0bf3113d6b8a8feced91 283 Gene3D G3DSA:3.40.50.300 8 274 1.4E-63 T 12-10-2018 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 Gene3D G3DSA:3.90.740.10 199 240 2.6E-5 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 TIGRFAM TIGR00422 valS: valine--tRNA ligase 9 918 0.0 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 Gene3D G3DSA:1.10.287.380 864 935 1.9E-14 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 SUPERFAMILY SSF52374 11 627 4.29E-129 T 12-10-2018 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 44 55 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 SUPERFAMILY SSF46589 871 935 6.8E-10 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 SUPERFAMILY SSF47323 628 886 5.79E-61 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 Pfam PF08264 Anticodon-binding domain of tRNA 658 810 7.1E-41 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 SUPERFAMILY SSF50677 192 355 2.75E-56 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 Gene3D G3DSA:1.10.730.10 567 804 1.3E-68 T 12-10-2018 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 PRINTS PR00986 Valyl-tRNA synthetase signature 359 372 9.9E-37 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 PRINTS PR00986 Valyl-tRNA synthetase signature 461 482 9.9E-37 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 PRINTS PR00986 Valyl-tRNA synthetase signature 37 48 9.9E-37 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 PRINTS PR00986 Valyl-tRNA synthetase signature 492 510 9.9E-37 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 9.9E-37 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 617 5.4E-205 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 Hamap MF_02004 Valine--tRNA ligase [valS]. 5 936 15.619 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 Gene3D G3DSA:3.40.50.620 8 198 3.1E-59 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 871 933 1.0E-9 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 Gene3D G3DSA:3.90.740.10 241 295 2.7E-10 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFE_2204 b509e6281f720c3c8d9f00ed56d9d876 938 Gene3D G3DSA:3.40.50.620 323 541 2.9E-77 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2907 cffb69012d0ab80b348949d6b9476f0d 1120 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 277 1112 0.0 T 12-10-2018 IPR018667 Domain of unknown function DUF2126 AFE_2907 cffb69012d0ab80b348949d6b9476f0d 1120 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 7 83 1.6E-24 T 12-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal AFE_2907 cffb69012d0ab80b348949d6b9476f0d 1120 SUPERFAMILY SSF54001 9 337 6.98E-70 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFE_2907 cffb69012d0ab80b348949d6b9476f0d 1120 Pfam PF01841 Transglutaminase-like superfamily 137 246 2.3E-19 T 12-10-2018 IPR002931 Transglutaminase-like AFE_2907 cffb69012d0ab80b348949d6b9476f0d 1120 Gene3D G3DSA:3.10.620.30 105 280 3.3E-30 T 12-10-2018 AFE_2907 cffb69012d0ab80b348949d6b9476f0d 1120 SMART SM00460 172 248 2.6E-20 T 12-10-2018 IPR002931 Transglutaminase-like AFE_0980 de63870155169212952b01e0f82e298b 127 SUPERFAMILY SSF51230 4 125 1.44E-36 T 12-10-2018 IPR011053 Single hybrid motif AFE_0980 de63870155169212952b01e0f82e298b 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFE_0980 de63870155169212952b01e0f82e298b 127 Gene3D G3DSA:2.40.50.100 2 126 2.3E-43 T 12-10-2018 AFE_0980 de63870155169212952b01e0f82e298b 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 125 1.7E-44 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AFE_0980 de63870155169212952b01e0f82e298b 127 Pfam PF01597 Glycine cleavage H-protein 8 125 2.6E-39 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate AFE_0980 de63870155169212952b01e0f82e298b 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 126 36.471 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AFE_0846 3842742555471aef2938458b2f2c4a15 349 Gene3D G3DSA:3.40.50.720 160 315 7.9E-132 T 12-10-2018 AFE_0846 3842742555471aef2938458b2f2c4a15 349 SUPERFAMILY SSF50129 6 173 1.73E-50 T 12-10-2018 IPR011032 GroES-like superfamily AFE_0846 3842742555471aef2938458b2f2c4a15 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFE_0846 3842742555471aef2938458b2f2c4a15 349 SUPERFAMILY SSF51735 150 313 2.28E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0846 3842742555471aef2938458b2f2c4a15 349 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 179 207 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFE_0846 3842742555471aef2938458b2f2c4a15 349 Gene3D G3DSA:3.90.180.10 14 343 7.9E-132 T 12-10-2018 AFE_0846 3842742555471aef2938458b2f2c4a15 349 Pfam PF00107 Zinc-binding dehydrogenase 186 309 1.2E-22 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFE_0846 3842742555471aef2938458b2f2c4a15 349 SMART SM00829 11 343 0.0011 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFE_0846 3842742555471aef2938458b2f2c4a15 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 144 2.9E-27 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFE_2872 9d08df161393236618aebe8b01989743 144 Pfam PF02643 Uncharacterized ACR, COG1430 42 137 1.3E-18 T 12-10-2018 IPR003795 Protein of unknown function DUF192 AFE_2872 9d08df161393236618aebe8b01989743 144 Gene3D G3DSA:2.60.120.1140 22 137 1.2E-10 T 12-10-2018 IPR038695 Saro_0823-like superfamily AFE_0115 d71284c99c64a02724fd09a9f765ebb2 478 Pfam PF03724 META domain 363 473 1.8E-24 T 12-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ AFE_0115 d71284c99c64a02724fd09a9f765ebb2 478 Pfam PF17185 NlpE C-terminal OB domain 266 354 5.2E-18 T 12-10-2018 IPR033450 NlpE, C-terminal OB domain AFE_0115 d71284c99c64a02724fd09a9f765ebb2 478 Pfam PF09619 Type III secretion system lipoprotein chaperone (YscW) 40 132 3.0E-20 T 12-10-2018 IPR039366 YscW/ExsB AFE_0115 d71284c99c64a02724fd09a9f765ebb2 478 Gene3D G3DSA:2.40.128.270 372 471 1.2E-14 T 12-10-2018 IPR038670 HslJ-like superfamily AFE_0115 d71284c99c64a02724fd09a9f765ebb2 478 Pfam PF04170 NlpE N-terminal domain 162 247 1.4E-5 T 12-10-2018 IPR007298 Copper resistance lipoprotein NlpE AFE_0115 d71284c99c64a02724fd09a9f765ebb2 478 Gene3D G3DSA:2.40.50.540 265 371 1.7E-22 T 12-10-2018 IPR038139 NlpE, C-terminal domain superfamily AFE_2642 a8706057111903791cd047c39116e878 425 Gene3D G3DSA:1.20.1250.20 247 425 2.9E-25 T 12-10-2018 AFE_2642 a8706057111903791cd047c39116e878 425 Gene3D G3DSA:1.20.1250.20 23 212 3.9E-22 T 12-10-2018 AFE_2642 a8706057111903791cd047c39116e878 425 SUPERFAMILY SSF103473 21 420 4.97E-59 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_2642 a8706057111903791cd047c39116e878 425 Pfam PF07690 Major Facilitator Superfamily 30 208 5.8E-22 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_2642 a8706057111903791cd047c39116e878 425 Pfam PF07690 Major Facilitator Superfamily 249 421 4.9E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_2642 a8706057111903791cd047c39116e878 425 ProSitePatterns PS00216 Sugar transport proteins signature 1. 290 306 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFE_2255 12eca87313eb51b62b16cf0d96b50d2f 113 SMART SM00960 2 92 2.9E-5 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFE_2255 12eca87313eb51b62b16cf0d96b50d2f 113 SUPERFAMILY SSF103196 10 97 4.97E-8 T 12-10-2018 AFE_2255 12eca87313eb51b62b16cf0d96b50d2f 113 Pfam PF03259 Roadblock/LC7 domain 13 90 2.6E-5 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFE_2255 12eca87313eb51b62b16cf0d96b50d2f 113 Gene3D G3DSA:3.30.450.30 2 113 1.3E-11 T 12-10-2018 AFE_0277 3ebb1e991c5c497d114affc051860f43 153 TIGRFAM TIGR00086 smpB: SsrA-binding protein 5 147 2.8E-55 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFE_0277 3ebb1e991c5c497d114affc051860f43 153 ProSitePatterns PS01317 SsrA-binding protein. 23 35 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site AFE_0277 3ebb1e991c5c497d114affc051860f43 153 SUPERFAMILY SSF74982 3 129 3.01E-50 T 12-10-2018 IPR023620 Small protein B AFE_0277 3ebb1e991c5c497d114affc051860f43 153 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 5 129 4.0E-51 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFE_0277 3ebb1e991c5c497d114affc051860f43 153 Hamap MF_00023 SsrA-binding protein [smpB]. 1 152 73.91 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFE_0277 3ebb1e991c5c497d114affc051860f43 153 Gene3D G3DSA:2.40.280.10 1 125 1.2E-47 T 12-10-2018 IPR023620 Small protein B AFE_0277 3ebb1e991c5c497d114affc051860f43 153 Pfam PF01668 SmpB protein 5 147 6.2E-60 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFE_1673 06367bcf58c65bc13a76df3c0bbff544 557 SUPERFAMILY SSF52016 380 557 2.12E-57 T 12-10-2018 AFE_1673 06367bcf58c65bc13a76df3c0bbff544 557 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 5 557 45.565 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_1673 06367bcf58c65bc13a76df3c0bbff544 557 SUPERFAMILY SSF143975 4 378 1.83E-137 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_1673 06367bcf58c65bc13a76df3c0bbff544 557 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 557 2.5E-239 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_1673 06367bcf58c65bc13a76df3c0bbff544 557 Pfam PF00920 Dehydratase family 35 554 4.1E-210 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_1673 06367bcf58c65bc13a76df3c0bbff544 557 Gene3D G3DSA:3.50.30.80 379 528 4.0E-52 T 12-10-2018 AFE_1673 06367bcf58c65bc13a76df3c0bbff544 557 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_1673 06367bcf58c65bc13a76df3c0bbff544 557 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFE_0992 297c108fddac07f7f3d9d8073fa2ae8a 257 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 252 5.9E-81 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 AFE_0992 297c108fddac07f7f3d9d8073fa2ae8a 257 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 188 204 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AFE_0992 297c108fddac07f7f3d9d8073fa2ae8a 257 Gene3D G3DSA:3.20.20.140 1 254 1.0E-88 T 12-10-2018 AFE_0992 297c108fddac07f7f3d9d8073fa2ae8a 257 PIRSF PIRSF005902 1 256 1.7E-72 T 12-10-2018 IPR001130 TatD family GO:0016788 AFE_0992 297c108fddac07f7f3d9d8073fa2ae8a 257 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AFE_0992 297c108fddac07f7f3d9d8073fa2ae8a 257 SUPERFAMILY SSF51556 2 252 1.94E-84 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFE_0992 297c108fddac07f7f3d9d8073fa2ae8a 257 Pfam PF01026 TatD related DNase 3 251 5.3E-77 T 12-10-2018 IPR001130 TatD family GO:0016788 AFE_3229 c86a56111aa4a6e4c0b247d943dbbb43 768 Pfam PF00593 TonB dependent receptor 277 767 2.1E-37 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_3229 c86a56111aa4a6e4c0b247d943dbbb43 768 Gene3D G3DSA:2.170.130.10 57 183 4.3E-12 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_3229 c86a56111aa4a6e4c0b247d943dbbb43 768 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 159 8.5E-8 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain AFE_3229 c86a56111aa4a6e4c0b247d943dbbb43 768 SUPERFAMILY SSF56935 56 768 1.65E-75 T 12-10-2018 AFE_0827 7d346b53397d28d13e8f7dcd730591b8 526 Gene3D G3DSA:3.30.565.60 242 400 1.2E-38 T 12-10-2018 IPR038475 RecG, C-terminal domain superfamily AFE_0827 7d346b53397d28d13e8f7dcd730591b8 526 Pfam PF13271 Domain of unknown function (DUF4062) 2 89 5.1E-19 T 12-10-2018 IPR025139 Domain of unknown function DUF4062 AFE_0827 7d346b53397d28d13e8f7dcd730591b8 526 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 312 398 1.7E-22 T 12-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain AFE_0827 7d346b53397d28d13e8f7dcd730591b8 526 SUPERFAMILY SSF46785 475 520 5.31E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1862 66070ab28057d109036049a3a5b19a4e 74 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFE_1862 66070ab28057d109036049a3a5b19a4e 74 Gene3D G3DSA:3.30.70.100 4 67 1.4E-23 T 12-10-2018 AFE_1862 66070ab28057d109036049a3a5b19a4e 74 SUPERFAMILY SSF55008 4 66 7.72E-19 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFE_1862 66070ab28057d109036049a3a5b19a4e 74 Pfam PF00403 Heavy-metal-associated domain 6 63 2.9E-14 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFE_2045 72bca4778d962c49736448cd3d90633b 447 Gene3D G3DSA:1.20.1600.10 41 438 2.6E-52 T 12-10-2018 AFE_2045 72bca4778d962c49736448cd3d90633b 447 SUPERFAMILY SSF56954 22 441 1.16E-54 T 12-10-2018 AFE_2045 72bca4778d962c49736448cd3d90633b 447 Pfam PF02321 Outer membrane efflux protein 47 225 1.4E-14 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_2045 72bca4778d962c49736448cd3d90633b 447 Pfam PF02321 Outer membrane efflux protein 260 435 1.9E-20 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_0928 d937f404b41dbce35f90ac96db61b530 340 Pfam PF00586 AIR synthase related protein, N-terminal domain 29 141 1.1E-22 T 12-10-2018 IPR016188 PurM-like, N-terminal domain AFE_0928 d937f404b41dbce35f90ac96db61b530 340 PIRSF PIRSF005303 1 326 1.7E-78 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFE_0928 d937f404b41dbce35f90ac96db61b530 340 SUPERFAMILY SSF55326 16 141 1.92E-31 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFE_0928 d937f404b41dbce35f90ac96db61b530 340 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 314 2.6E-86 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFE_0928 d937f404b41dbce35f90ac96db61b530 340 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 339 25.771 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AFE_0928 d937f404b41dbce35f90ac96db61b530 340 SUPERFAMILY SSF56042 147 310 2.09E-28 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFE_0928 d937f404b41dbce35f90ac96db61b530 340 Gene3D G3DSA:3.30.1330.10 2 145 5.9E-40 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFE_0928 d937f404b41dbce35f90ac96db61b530 340 Pfam PF02769 AIR synthase related protein, C-terminal domain 153 310 1.4E-9 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFE_0928 d937f404b41dbce35f90ac96db61b530 340 Gene3D G3DSA:3.90.650.10 149 335 3.3E-40 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFE_1105 8a567c4b01559060833fa2b59bb1bd1e 196 Pfam PF00239 Resolvase, N terminal domain 51 187 4.0E-17 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFE_1105 8a567c4b01559060833fa2b59bb1bd1e 196 ProSitePatterns PS00397 Site-specific recombinases active site. 53 61 - T 12-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AFE_1105 8a567c4b01559060833fa2b59bb1bd1e 196 SMART SM00857 50 179 3.4E-16 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFE_1105 8a567c4b01559060833fa2b59bb1bd1e 196 Gene3D G3DSA:3.40.50.1390 47 145 2.6E-17 T 12-10-2018 AFE_1105 8a567c4b01559060833fa2b59bb1bd1e 196 SUPERFAMILY SSF53041 49 179 2.49E-20 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFE_0038 7aeec07b9237991a29700575b125bc5a 370 Pfam PF13437 HlyD family secretion protein 217 337 8.2E-17 T 12-10-2018 AFE_0038 7aeec07b9237991a29700575b125bc5a 370 SUPERFAMILY SSF111369 62 269 3.01E-6 T 12-10-2018 AFE_0038 7aeec07b9237991a29700575b125bc5a 370 Gene3D G3DSA:2.40.30.170 231 347 1.4E-29 T 12-10-2018 AFE_0038 7aeec07b9237991a29700575b125bc5a 370 Gene3D G3DSA:2.40.50.100 61 132 2.1E-5 T 12-10-2018 AFE_2280 aca1fd10082f43544cb2b4eeca705083 365 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 3 355 1.0E-151 T 12-10-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 AFE_2280 aca1fd10082f43544cb2b4eeca705083 365 PIRSF PIRSF007313 1 364 3.7E-147 T 12-10-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 AFE_2906 05aef0504be095f16446bd00f4c5c7f5 328 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 307 1.3E-79 T 12-10-2018 IPR007296 Domain of unknown function DUF403 AFE_2224 b1ee68da4e9b11dcfc4fdaff3402ec8b 786 Pfam PF09137 Glucodextranase, domain N 9 264 9.9E-71 T 12-10-2018 IPR015220 Glucodextranase, N-terminal KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 AFE_2224 b1ee68da4e9b11dcfc4fdaff3402ec8b 786 Pfam PF00723 Glycosyl hydrolases family 15 368 585 1.9E-10 T 12-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 AFE_2224 b1ee68da4e9b11dcfc4fdaff3402ec8b 786 Pfam PF00723 Glycosyl hydrolases family 15 280 348 6.0E-8 T 12-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 AFE_2224 b1ee68da4e9b11dcfc4fdaff3402ec8b 786 ProSitePatterns PS00820 Glucoamylase active site region signature. 421 431 - T 12-10-2018 IPR000165 Glucoamylase GO:0004339|GO:0005976 KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 AFE_2224 b1ee68da4e9b11dcfc4fdaff3402ec8b 786 Gene3D G3DSA:2.70.98.10 2 265 2.4E-67 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFE_2224 b1ee68da4e9b11dcfc4fdaff3402ec8b 786 Gene3D G3DSA:1.50.10.10 272 689 1.3E-150 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFE_2224 b1ee68da4e9b11dcfc4fdaff3402ec8b 786 SUPERFAMILY SSF48208 275 686 4.42E-70 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFE_2224 b1ee68da4e9b11dcfc4fdaff3402ec8b 786 SUPERFAMILY SSF74650 7 266 1.4E-53 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFE_0763 c9023e3980e5ca0b2df7d61ed927e1ec 778 Pfam PF07715 TonB-dependent Receptor Plug Domain 75 154 7.0E-8 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain AFE_0763 c9023e3980e5ca0b2df7d61ed927e1ec 778 SUPERFAMILY SSF56935 75 776 1.06E-61 T 12-10-2018 AFE_0763 c9023e3980e5ca0b2df7d61ed927e1ec 778 Gene3D G3DSA:2.170.130.10 70 194 1.2E-7 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_0763 c9023e3980e5ca0b2df7d61ed927e1ec 778 Pfam PF00593 TonB dependent receptor 366 775 1.8E-29 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_0602 377c5b367c7ae055e56606a0d9212c6c 294 SUPERFAMILY SSF53807 17 284 1.96E-54 T 12-10-2018 AFE_0602 377c5b367c7ae055e56606a0d9212c6c 294 Gene3D G3DSA:3.40.50.1980 25 168 1.5E-30 T 12-10-2018 AFE_0602 377c5b367c7ae055e56606a0d9212c6c 294 Pfam PF01297 Zinc-uptake complex component A periplasmic 31 283 4.4E-39 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 AFE_0713 d95bfa9c9c6485fefcdd288fd5e4522a 97 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 8.8E-21 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_0713 d95bfa9c9c6485fefcdd288fd5e4522a 97 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 47 63 8.8E-21 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_0713 d95bfa9c9c6485fefcdd288fd5e4522a 97 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 20 36 8.8E-21 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_0713 d95bfa9c9c6485fefcdd288fd5e4522a 97 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 65 77 8.8E-21 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_0713 d95bfa9c9c6485fefcdd288fd5e4522a 97 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 12-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site AFE_0713 d95bfa9c9c6485fefcdd288fd5e4522a 97 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 85 6.0E-23 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_0713 d95bfa9c9c6485fefcdd288fd5e4522a 97 Pfam PF01455 HupF/HypC family 1 74 7.3E-25 T 12-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFE_0713 d95bfa9c9c6485fefcdd288fd5e4522a 97 Gene3D G3DSA:2.40.50.970 1 83 4.5E-25 T 12-10-2018 IPR037254 HupF/HypC superfamily AFE_0713 d95bfa9c9c6485fefcdd288fd5e4522a 97 SUPERFAMILY SSF159127 1 87 1.57E-25 T 12-10-2018 IPR037254 HupF/HypC superfamily AFE_1668 3d857172d42c6975291a4e2139452f2c 259 SUPERFAMILY SSF46785 12 83 1.56E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1668 3d857172d42c6975291a4e2139452f2c 259 Pfam PF09339 IclR helix-turn-helix domain 15 60 1.8E-6 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFE_1668 3d857172d42c6975291a4e2139452f2c 259 SUPERFAMILY SSF55781 69 248 2.68E-38 T 12-10-2018 AFE_1668 3d857172d42c6975291a4e2139452f2c 259 Pfam PF01614 Bacterial transcriptional regulator 129 248 6.4E-21 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFE_1668 3d857172d42c6975291a4e2139452f2c 259 Gene3D G3DSA:1.10.10.10 1 72 3.8E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1668 3d857172d42c6975291a4e2139452f2c 259 Gene3D G3DSA:3.30.450.40 80 257 1.0E-43 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_1668 3d857172d42c6975291a4e2139452f2c 259 SMART SM00346 12 101 4.9E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFE_0337 a4fc136ade87145c5111da270326f798 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 7.1E-58 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 AFE_0337 a4fc136ade87145c5111da270326f798 122 SUPERFAMILY SSF50193 1 122 1.83E-52 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 AFE_0337 a4fc136ade87145c5111da270326f798 122 SMART SM01374 1 122 3.3E-86 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFE_0337 a4fc136ade87145c5111da270326f798 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.2E-54 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFE_0337 a4fc136ade87145c5111da270326f798 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.081 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFE_0337 a4fc136ade87145c5111da270326f798 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0337 a4fc136ade87145c5111da270326f798 122 Gene3D G3DSA:2.40.150.20 1 122 7.1E-54 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 AFE_0574 4e4875fab197474c78b05093441054e2 361 SUPERFAMILY SSF102114 52 321 1.53E-36 T 12-10-2018 AFE_0574 4e4875fab197474c78b05093441054e2 361 PIRSF PIRSF004869 3 319 1.9E-90 T 12-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted AFE_0574 4e4875fab197474c78b05093441054e2 361 Pfam PF04055 Radical SAM superfamily 86 236 9.5E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFE_0574 4e4875fab197474c78b05093441054e2 361 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 12 359 1.7E-191 T 12-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme AFE_0574 4e4875fab197474c78b05093441054e2 361 Gene3D G3DSA:3.20.20.70 69 292 5.1E-34 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2105 90202119714f434ccf266b1942b2c4f1 239 SUPERFAMILY SSF52540 18 214 6.2E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2105 90202119714f434ccf266b1942b2c4f1 239 SMART SM00382 31 209 1.4E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2105 90202119714f434ccf266b1942b2c4f1 239 Pfam PF00005 ABC transporter 21 162 2.9E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_2105 90202119714f434ccf266b1942b2c4f1 239 Gene3D G3DSA:3.40.50.300 3 232 4.8E-45 T 12-10-2018 AFE_0022 cb9dcfacbb51639ae1643ce283eaef84 199 Pfam PF14334 Domain of unknown function (DUF4390) 41 194 2.6E-26 T 12-10-2018 IPR025500 Protein of unknown function DUF4390 AFE_0177 abd4ca8e4ee889970dfc97bef9ba6fe8 200 SUPERFAMILY SSF52833 1 99 6.6E-22 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0177 abd4ca8e4ee889970dfc97bef9ba6fe8 200 Gene3D G3DSA:1.20.1050.10 79 191 3.1E-57 T 12-10-2018 AFE_0177 abd4ca8e4ee889970dfc97bef9ba6fe8 200 Gene3D G3DSA:3.40.30.10 2 194 3.1E-57 T 12-10-2018 AFE_0177 abd4ca8e4ee889970dfc97bef9ba6fe8 200 Pfam PF00043 Glutathione S-transferase, C-terminal domain 117 192 2.3E-4 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal AFE_0177 abd4ca8e4ee889970dfc97bef9ba6fe8 200 SUPERFAMILY SSF47616 74 199 6.26E-10 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily AFE_0177 abd4ca8e4ee889970dfc97bef9ba6fe8 200 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 77 1.2E-20 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 AFE_1606 98813b0c8cfa21a0a17349634cd591d6 315 Gene3D G3DSA:3.40.50.300 2 232 2.7E-62 T 12-10-2018 AFE_1606 98813b0c8cfa21a0a17349634cd591d6 315 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_1606 98813b0c8cfa21a0a17349634cd591d6 315 SMART SM00382 33 214 8.2E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1606 98813b0c8cfa21a0a17349634cd591d6 315 SUPERFAMILY SSF52540 8 227 3.13E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1606 98813b0c8cfa21a0a17349634cd591d6 315 Pfam PF00005 ABC transporter 25 167 7.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_1764 144b8e674f2ff2b80d222c6fba19dee9 230 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 29 225 3.2E-44 T 12-10-2018 IPR006214 Bax inhibitor 1-related AFE_2811 86f353832b2692c4decca5a48d229d31 101 Pfam PF11839 Alanine-zipper, major outer membrane lipoprotein 34 101 2.3E-17 T 12-10-2018 IPR021793 Major outer membrane lipoprotein Oprl AFE_2661 ffd688f4f9c1933177de75b96ce10105 358 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 93 335 4.0E-106 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 AFE_2661 ffd688f4f9c1933177de75b96ce10105 358 SUPERFAMILY SSF117916 2 73 4.9E-6 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFE_2661 ffd688f4f9c1933177de75b96ce10105 358 SUPERFAMILY SSF52540 95 340 2.06E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2661 ffd688f4f9c1933177de75b96ce10105 358 Hamap MF_02040 Iron-sulfur cluster carrier protein. 88 340 39.326 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein AFE_2661 ffd688f4f9c1933177de75b96ce10105 358 Gene3D G3DSA:3.40.50.300 81 335 1.1E-89 T 12-10-2018 AFE_2661 ffd688f4f9c1933177de75b96ce10105 358 ProSitePatterns PS01215 Mrp family signature. 199 215 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 AFE_0751 0594d829cdc8a7a0803314aa12dc538b 141 Pfam PF00582 Universal stress protein family 1 140 7.5E-27 T 12-10-2018 IPR006016 UspA AFE_0751 0594d829cdc8a7a0803314aa12dc538b 141 SUPERFAMILY SSF52402 2 141 6.11E-31 T 12-10-2018 AFE_0751 0594d829cdc8a7a0803314aa12dc538b 141 Gene3D G3DSA:3.40.50.620 1 140 1.6E-34 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0751 0594d829cdc8a7a0803314aa12dc538b 141 PRINTS PR01438 Universal stress protein signature 101 113 1.1E-16 T 12-10-2018 IPR006015 Universal stress protein A AFE_0751 0594d829cdc8a7a0803314aa12dc538b 141 PRINTS PR01438 Universal stress protein signature 2 20 1.1E-16 T 12-10-2018 IPR006015 Universal stress protein A AFE_0751 0594d829cdc8a7a0803314aa12dc538b 141 PRINTS PR01438 Universal stress protein signature 119 141 1.1E-16 T 12-10-2018 IPR006015 Universal stress protein A AFE_2325 642252edc3a1b2752192e577be858ada 120 Pfam PF12732 YtxH-like protein 19 92 4.5E-15 T 12-10-2018 IPR024623 Uncharacterised protein family YtxH AFE_1368 a9bc4ce185412ca860e04c5b5425773f 117 Pfam PF01927 Mut7-C RNAse domain 1 67 6.6E-7 T 12-10-2018 IPR002782 Mut7-C RNAse domain AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 89 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 Gene3D G3DSA:1.20.1250.20 9 452 8.3E-128 T 12-10-2018 AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 PRINTS PR00171 Sugar transporter signature 264 274 3.2E-29 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 PRINTS PR00171 Sugar transporter signature 376 388 3.2E-29 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 PRINTS PR00171 Sugar transporter signature 26 36 3.2E-29 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 PRINTS PR00171 Sugar transporter signature 353 374 3.2E-29 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 PRINTS PR00171 Sugar transporter signature 109 128 3.2E-29 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 11 448 4.7E-120 T 12-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 Pfam PF00083 Sugar (and other) transporter 19 449 9.8E-121 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFE_2312 7ef86bfa686e91a131f8cd0ac87130e9 452 SUPERFAMILY SSF103473 5 450 1.09E-69 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_0441 c6bf6032c3bf275c8382aaa554313002 379 Gene3D G3DSA:3.90.25.10 211 354 4.4E-124 T 12-10-2018 AFE_0441 c6bf6032c3bf275c8382aaa554313002 379 Pfam PF16363 GDP-mannose 4,6 dehydratase 14 347 2.6E-95 T 12-10-2018 IPR016040 NAD(P)-binding domain AFE_0441 c6bf6032c3bf275c8382aaa554313002 379 SUPERFAMILY SSF51735 10 374 1.38E-90 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0441 c6bf6032c3bf275c8382aaa554313002 379 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 12 361 2.7E-143 T 12-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 AFE_0441 c6bf6032c3bf275c8382aaa554313002 379 Gene3D G3DSA:3.40.50.720 12 346 4.4E-124 T 12-10-2018 AFE_0441 c6bf6032c3bf275c8382aaa554313002 379 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_0788 d50684696faa440fc568c3d87ebc41c9 439 Pfam PF01494 FAD binding domain 16 328 1.7E-21 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 AFE_0788 d50684696faa440fc568c3d87ebc41c9 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 5.5E-7 T 12-10-2018 AFE_0788 d50684696faa440fc568c3d87ebc41c9 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 17 39 5.5E-7 T 12-10-2018 AFE_0788 d50684696faa440fc568c3d87ebc41c9 439 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 5.5E-7 T 12-10-2018 AFE_0788 d50684696faa440fc568c3d87ebc41c9 439 SUPERFAMILY SSF51905 16 397 2.14E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0788 d50684696faa440fc568c3d87ebc41c9 439 Gene3D G3DSA:3.50.50.60 12 415 8.4E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1867 3ee6fc5d7c8337b733096a83790ad4d2 151 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 45 145 9.8E-17 T 12-10-2018 IPR019223 Domain of unknown function DUF2147 AFE_1867 3ee6fc5d7c8337b733096a83790ad4d2 151 Gene3D G3DSA:2.40.128.520 41 151 1.7E-13 T 12-10-2018 AFE_2749 6c3d0925a449d380f294cfa9e5b96e1b 110 SUPERFAMILY SSF75169 4 110 8.24E-17 T 12-10-2018 IPR027396 DsrEFH-like AFE_2749 6c3d0925a449d380f294cfa9e5b96e1b 110 Gene3D G3DSA:3.40.1260.10 2 110 3.9E-19 T 12-10-2018 IPR027396 DsrEFH-like AFE_1199 5374794337cac5bce1f54ca864f87dda 145 Pfam PF00075 RNase H 4 143 1.7E-36 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 AFE_1199 5374794337cac5bce1f54ca864f87dda 145 Gene3D G3DSA:3.30.420.10 1 145 3.8E-47 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_1199 5374794337cac5bce1f54ca864f87dda 145 SUPERFAMILY SSF53098 3 144 1.77E-43 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_1922 675ec61aa53b1aaac8ff5a15690b90e5 405 SUPERFAMILY SSF111352 10 378 8.37E-93 T 12-10-2018 AFE_1922 675ec61aa53b1aaac8ff5a15690b90e5 405 Pfam PF00909 Ammonium Transporter Family 15 397 9.5E-87 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AFE_1922 675ec61aa53b1aaac8ff5a15690b90e5 405 Gene3D G3DSA:1.10.3430.10 7 405 2.5E-99 T 12-10-2018 IPR029020 Ammonium/urea transporter AFE_1922 675ec61aa53b1aaac8ff5a15690b90e5 405 ProSitePatterns PS01219 Ammonium transporters signature. 160 185 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AFE_1800 9a1af9392df6592c647708ccd7433225 116 SUPERFAMILY SSF51604 9 111 7.07E-36 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFE_1800 9a1af9392df6592c647708ccd7433225 116 Pfam PF00113 Enolase, C-terminal TIM barrel domain 10 111 2.5E-38 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_1800 9a1af9392df6592c647708ccd7433225 116 SMART SM01192 1 112 1.7E-11 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_1800 9a1af9392df6592c647708ccd7433225 116 Gene3D G3DSA:3.20.20.120 3 116 3.2E-37 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFE_1800 9a1af9392df6592c647708ccd7433225 116 PRINTS PR00148 Enolase signature 50 67 9.8E-12 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_1800 9a1af9392df6592c647708ccd7433225 116 PRINTS PR00148 Enolase signature 21 35 9.8E-12 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFE_2176 11e0f6db28f25caf2228e2f98b62d85e 343 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 7 342 1.2E-111 T 12-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 AFE_2176 11e0f6db28f25caf2228e2f98b62d85e 343 Gene3D G3DSA:3.75.10.10 3 343 9.2E-120 T 12-10-2018 AFE_2176 11e0f6db28f25caf2228e2f98b62d85e 343 SUPERFAMILY SSF55909 3 343 2.68E-118 T 12-10-2018 AFE_2990 ce543fa485dddf7b72bd0198dfe62202 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 291 7.0E-26 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFE_2990 ce543fa485dddf7b72bd0198dfe62202 296 Gene3D G3DSA:1.10.3720.10 85 296 3.0E-18 T 12-10-2018 IPR035906 MetI-like superfamily AFE_2990 ce543fa485dddf7b72bd0198dfe62202 296 SUPERFAMILY SSF161098 92 281 2.88E-22 T 12-10-2018 IPR035906 MetI-like superfamily AFE_2993 2ab7fb972efde18e9631f00ae08feb5b 613 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 46 154 8.2E-20 T 12-10-2018 IPR024618 Domain of unknown function DUF3857 AFE_2993 2ab7fb972efde18e9631f00ae08feb5b 613 SUPERFAMILY SSF54001 259 327 9.32E-5 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFE_2993 2ab7fb972efde18e9631f00ae08feb5b 613 Gene3D G3DSA:2.60.40.3140 34 183 3.6E-20 T 12-10-2018 AFE_2993 2ab7fb972efde18e9631f00ae08feb5b 613 Pfam PF01841 Transglutaminase-like superfamily 258 326 7.5E-6 T 12-10-2018 IPR002931 Transglutaminase-like AFE_2993 2ab7fb972efde18e9631f00ae08feb5b 613 Gene3D G3DSA:3.10.620.30 234 373 1.2E-20 T 12-10-2018 AFE_0092 c22e8afd9110eb4fccb4d1c67ada662a 358 Gene3D G3DSA:1.10.3290.10 32 267 3.0E-53 T 12-10-2018 IPR036597 Fido-like domain superfamily AFE_0092 c22e8afd9110eb4fccb4d1c67ada662a 358 Pfam PF13784 Fic/DOC family N-terminal 13 92 3.4E-26 T 12-10-2018 IPR025758 Fic/DOC N-terminal AFE_0092 c22e8afd9110eb4fccb4d1c67ada662a 358 Pfam PF02661 Fic/DOC family 101 205 4.2E-22 T 12-10-2018 IPR003812 Fido domain AFE_0092 c22e8afd9110eb4fccb4d1c67ada662a 358 PIRSF PIRSF038925 3 354 4.1E-109 T 12-10-2018 IPR026287 Adenosine monophosphate-protein transferase AFE_0092 c22e8afd9110eb4fccb4d1c67ada662a 358 SUPERFAMILY SSF140931 77 271 9.29E-46 T 12-10-2018 IPR036597 Fido-like domain superfamily AFE_0834 9180beaac4cdc025582d6209ed47c31e 313 Gene3D G3DSA:1.10.443.10 98 310 1.2E-37 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_0834 9180beaac4cdc025582d6209ed47c31e 313 Pfam PF00589 Phage integrase family 107 291 1.5E-26 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_0834 9180beaac4cdc025582d6209ed47c31e 313 SUPERFAMILY SSF56349 3 299 1.02E-38 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_0508 9180beaac4cdc025582d6209ed47c31e 313 Gene3D G3DSA:1.10.443.10 98 310 1.2E-37 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_0508 9180beaac4cdc025582d6209ed47c31e 313 Pfam PF00589 Phage integrase family 107 291 1.5E-26 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_0508 9180beaac4cdc025582d6209ed47c31e 313 SUPERFAMILY SSF56349 3 299 1.02E-38 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_2398 9180beaac4cdc025582d6209ed47c31e 313 Gene3D G3DSA:1.10.443.10 98 310 1.2E-37 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_2398 9180beaac4cdc025582d6209ed47c31e 313 Pfam PF00589 Phage integrase family 107 291 1.5E-26 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_2398 9180beaac4cdc025582d6209ed47c31e 313 SUPERFAMILY SSF56349 3 299 1.02E-38 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_0750 d5c7a6bd6fc03d9161d41443e6b16871 250 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFE_0750 d5c7a6bd6fc03d9161d41443e6b16871 250 Gene3D G3DSA:1.20.120.1760 8 161 9.2E-16 T 12-10-2018 AFE_0750 d5c7a6bd6fc03d9161d41443e6b16871 250 Pfam PF01066 CDP-alcohol phosphatidyltransferase 12 76 2.2E-14 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFE_0750 d5c7a6bd6fc03d9161d41443e6b16871 250 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 19 182 3.2E-39 T 12-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 AFE_2014 eff20d7248e6a6e601c6b9c6b336418f 159 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 35 83 6.9E-13 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFE_2014 eff20d7248e6a6e601c6b9c6b336418f 159 Pfam PF02627 Carboxymuconolactone decarboxylase family 18 99 2.2E-19 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFE_2014 eff20d7248e6a6e601c6b9c6b336418f 159 Gene3D G3DSA:1.20.1290.10 9 154 2.1E-43 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFE_2014 eff20d7248e6a6e601c6b9c6b336418f 159 SUPERFAMILY SSF69118 12 152 4.06E-41 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFE_0305 236f16650aeb99ce6d38fc0ac61014a2 560 Pfam PF03109 ABC1 family 115 234 6.7E-34 T 12-10-2018 IPR004147 UbiB domain AFE_0305 236f16650aeb99ce6d38fc0ac61014a2 560 SUPERFAMILY SSF56112 97 435 6.61E-39 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFE_0305 236f16650aeb99ce6d38fc0ac61014a2 560 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 8 443 3.7E-168 T 12-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 AFE_0157 be6d608320c7d3ff10817e42009e7c96 133 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 113 1.2E-46 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFE_0157 be6d608320c7d3ff10817e42009e7c96 133 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 117 31.386 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFE_0157 be6d608320c7d3ff10817e42009e7c96 133 Pfam PF02675 S-adenosylmethionine decarboxylase 8 113 1.1E-39 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFE_0157 be6d608320c7d3ff10817e42009e7c96 133 Gene3D G3DSA:3.30.160.750 63 129 2.4E-27 T 12-10-2018 AFE_0157 be6d608320c7d3ff10817e42009e7c96 133 Gene3D G3DSA:3.30.360.110 1 62 7.3E-25 T 12-10-2018 AFE_0157 be6d608320c7d3ff10817e42009e7c96 133 SUPERFAMILY SSF56276 3 115 3.14E-43 T 12-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 AFE_0164 02cb7defafb3e1d924ef8eb575d89a17 87 Gene3D G3DSA:3.10.290.10 5 82 5.0E-21 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFE_0164 02cb7defafb3e1d924ef8eb575d89a17 87 PIRSF PIRSF038881 5 84 5.2E-20 T 12-10-2018 IPR025490 RNA-binding protein, HP1423 type AFE_0164 02cb7defafb3e1d924ef8eb575d89a17 87 SMART SM00363 5 64 2.7E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0164 02cb7defafb3e1d924ef8eb575d89a17 87 Pfam PF01479 S4 domain 6 50 1.6E-9 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0164 02cb7defafb3e1d924ef8eb575d89a17 87 SUPERFAMILY SSF55174 5 72 1.7E-16 T 12-10-2018 AFE_1091 92833d7cb9e91fa1a0f01f1e67ddc69f 184 SUPERFAMILY SSF51306 62 183 5.13E-22 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFE_1091 92833d7cb9e91fa1a0f01f1e67ddc69f 184 Pfam PF10502 Signal peptidase, peptidase S26 73 181 1.6E-12 T 12-10-2018 IPR019533 Peptidase S26 AFE_1091 92833d7cb9e91fa1a0f01f1e67ddc69f 184 Gene3D G3DSA:2.10.109.10 61 184 1.1E-15 T 12-10-2018 AFE_1402 fefe6bc00ea71e7518967e013f237f27 255 TIGRFAM TIGR00613 reco: DNA repair protein RecO 8 196 7.9E-25 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFE_1402 fefe6bc00ea71e7518967e013f237f27 255 Pfam PF11967 Recombination protein O N terminal 7 78 1.7E-15 T 12-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal AFE_1402 fefe6bc00ea71e7518967e013f237f27 255 Pfam PF02565 Recombination protein O C terminal 87 231 2.4E-22 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFE_1402 fefe6bc00ea71e7518967e013f237f27 255 Gene3D G3DSA:1.20.1440.120 80 246 1.7E-34 T 12-10-2018 AFE_1402 fefe6bc00ea71e7518967e013f237f27 255 SUPERFAMILY SSF50249 7 79 4.97E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_1402 fefe6bc00ea71e7518967e013f237f27 255 Hamap MF_00201 DNA repair protein RecO [recO]. 3 237 20.561 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFE_1402 fefe6bc00ea71e7518967e013f237f27 255 SUPERFAMILY SSF57863 91 203 4.97E-19 T 12-10-2018 IPR037278 ARFGAP/RecO-like zinc finger AFE_1402 fefe6bc00ea71e7518967e013f237f27 255 Gene3D G3DSA:2.40.50.140 4 77 1.1E-22 T 12-10-2018 AFE_0073 8aaa347f9dc0d97ee798f5d358013ff0 488 Pfam PF02397 Bacterial sugar transferase 291 482 1.7E-65 T 12-10-2018 IPR003362 Bacterial sugar transferase AFE_0073 8aaa347f9dc0d97ee798f5d358013ff0 488 Pfam PF13727 CoA-binding domain 86 187 4.6E-7 T 12-10-2018 AFE_0073 8aaa347f9dc0d97ee798f5d358013ff0 488 TIGRFAM TIGR03022 WbaP_sugtrans: undecaprenyl-phosphate galactose phosphotransferase WbaP 21 488 3.5E-180 T 12-10-2018 IPR017472 Undecaprenyl-phosphate galactose phosphotransferase, WbaP GO:0000271|GO:0005886|GO:0016021|GO:0016740 AFE_0073 8aaa347f9dc0d97ee798f5d358013ff0 488 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 24 488 6.8E-122 T 12-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase AFE_1644 0e2ca8b99f962446d89d843cd8008caf 155 Pfam PF06146 Phosphate-starvation-inducible E 70 139 2.3E-12 T 12-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like AFE_0518 99a1afcadafc478c76dd5aeadfed2dea 197 Gene3D G3DSA:3.40.470.10 4 196 6.8E-67 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_0518 99a1afcadafc478c76dd5aeadfed2dea 197 SUPERFAMILY SSF52141 8 193 4.25E-50 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_0518 99a1afcadafc478c76dd5aeadfed2dea 197 SMART SM00986 30 186 3.0E-26 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_0518 99a1afcadafc478c76dd5aeadfed2dea 197 SMART SM00987 30 186 3.0E-26 T 12-10-2018 AFE_0518 99a1afcadafc478c76dd5aeadfed2dea 197 Pfam PF03167 Uracil DNA glycosylase superfamily 34 183 5.8E-22 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFE_2061 7069fdb0525848ce500c804cb61c9bc1 449 Pfam PF01595 Domain of unknown function DUF21 16 208 7.6E-45 T 12-10-2018 IPR002550 CNNM, transmembrane domain AFE_2061 7069fdb0525848ce500c804cb61c9bc1 449 Gene3D G3DSA:3.10.580.10 210 354 1.4E-34 T 12-10-2018 AFE_2061 7069fdb0525848ce500c804cb61c9bc1 449 Pfam PF03471 Transporter associated domain 363 438 9.0E-19 T 12-10-2018 IPR005170 Transporter-associated domain AFE_2061 7069fdb0525848ce500c804cb61c9bc1 449 SUPERFAMILY SSF54631 217 356 5.61E-25 T 12-10-2018 AFE_2061 7069fdb0525848ce500c804cb61c9bc1 449 SMART SM01091 362 440 7.2E-23 T 12-10-2018 IPR005170 Transporter-associated domain AFE_2061 7069fdb0525848ce500c804cb61c9bc1 449 SUPERFAMILY SSF56176 360 444 2.54E-18 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFE_2061 7069fdb0525848ce500c804cb61c9bc1 449 Pfam PF00571 CBS domain 227 285 1.5E-5 T 12-10-2018 IPR000644 CBS domain AFE_2061 7069fdb0525848ce500c804cb61c9bc1 449 Gene3D G3DSA:3.30.465.10 355 439 6.2E-17 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFE_2383 3af11c0bd141605ef7c01d03d0999053 490 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 455 3.5E-159 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFE_2383 3af11c0bd141605ef7c01d03d0999053 490 Gene3D G3DSA:3.40.1670.10 337 454 7.0E-48 T 12-10-2018 AFE_2383 3af11c0bd141605ef7c01d03d0999053 490 SUPERFAMILY SSF143968 323 481 5.62E-62 T 12-10-2018 AFE_2383 3af11c0bd141605ef7c01d03d0999053 490 SUPERFAMILY SSF50475 3 322 1.92E-117 T 12-10-2018 AFE_2383 3af11c0bd141605ef7c01d03d0999053 490 Gene3D G3DSA:1.20.5.570 455 486 6.4E-9 T 12-10-2018 AFE_2383 3af11c0bd141605ef7c01d03d0999053 490 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 431 1.5E-162 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AFE_1016 f0e043ba8f0099c2ad165690055d1a2e 289 Pfam PF02600 Disulfide bond formation protein DsbB 157 230 3.8E-9 T 12-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 AFE_1016 f0e043ba8f0099c2ad165690055d1a2e 289 Gene3D G3DSA:1.20.1550.10 153 264 6.7E-7 T 12-10-2018 IPR023380 DsbB-like superfamily AFE_1016 f0e043ba8f0099c2ad165690055d1a2e 289 SUPERFAMILY SSF158442 159 279 7.59E-9 T 12-10-2018 IPR023380 DsbB-like superfamily AFE_1857 8fb002730a0ef758321312bba239417e 261 SUPERFAMILY SSF51735 8 253 3.15E-86 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1857 8fb002730a0ef758321312bba239417e 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_1857 8fb002730a0ef758321312bba239417e 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 1.8E-67 T 12-10-2018 AFE_1857 8fb002730a0ef758321312bba239417e 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1857 8fb002730a0ef758321312bba239417e 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1857 8fb002730a0ef758321312bba239417e 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1857 8fb002730a0ef758321312bba239417e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1857 8fb002730a0ef758321312bba239417e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1857 8fb002730a0ef758321312bba239417e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1857 8fb002730a0ef758321312bba239417e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1857 8fb002730a0ef758321312bba239417e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 5.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1857 8fb002730a0ef758321312bba239417e 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 5.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1857 8fb002730a0ef758321312bba239417e 261 Gene3D G3DSA:3.40.50.720 2 253 4.2E-85 T 12-10-2018 AFE_1858 435cd92d526427c40523f42d25affc0c 180 Gene3D G3DSA:2.70.98.10 2 114 2.4E-23 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFE_1858 435cd92d526427c40523f42d25affc0c 180 SUPERFAMILY SSF74650 5 90 1.57E-18 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFE_1858 435cd92d526427c40523f42d25affc0c 180 Pfam PF09137 Glucodextranase, domain N 7 95 7.9E-23 T 12-10-2018 IPR015220 Glucodextranase, N-terminal KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 AFE_0014 9df189ecdab5e49dad8fe875d88b8ba8 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 9.3E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFE_0014 9df189ecdab5e49dad8fe875d88b8ba8 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 9.3E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFE_0014 9df189ecdab5e49dad8fe875d88b8ba8 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 9.3E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFE_0014 9df189ecdab5e49dad8fe875d88b8ba8 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_0014 9df189ecdab5e49dad8fe875d88b8ba8 108 Pfam PF11953 Domain of unknown function (DUF3470) 67 106 2.1E-17 T 12-10-2018 IPR022569 Ferredoxin, C-terminal AFE_0014 9df189ecdab5e49dad8fe875d88b8ba8 108 Pfam PF00037 4Fe-4S binding domain 34 55 1.5E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_0014 9df189ecdab5e49dad8fe875d88b8ba8 108 Gene3D G3DSA:3.30.70.20 2 98 2.2E-30 T 12-10-2018 AFE_0014 9df189ecdab5e49dad8fe875d88b8ba8 108 SUPERFAMILY SSF54862 3 105 3.09E-22 T 12-10-2018 AFE_3176 d51a018a8977255708961811eced591b 275 Gene3D G3DSA:3.40.50.300 65 252 2.8E-43 T 12-10-2018 AFE_3176 d51a018a8977255708961811eced591b 275 Pfam PF01695 IstB-like ATP binding protein 57 233 4.5E-60 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 AFE_3176 d51a018a8977255708961811eced591b 275 SMART SM00382 102 234 3.1E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_3176 d51a018a8977255708961811eced591b 275 PIRSF PIRSF003073 1 255 3.5E-88 T 12-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein AFE_3176 d51a018a8977255708961811eced591b 275 SUPERFAMILY SSF52540 70 231 1.27E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1033 b6f6985abadd5ee32c8c9d1c4442253f 204 Gene3D G3DSA:3.40.50.1390 49 148 8.5E-22 T 12-10-2018 AFE_1033 b6f6985abadd5ee32c8c9d1c4442253f 204 Pfam PF00239 Resolvase, N terminal domain 52 181 4.9E-21 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFE_1033 b6f6985abadd5ee32c8c9d1c4442253f 204 SUPERFAMILY SSF53041 51 187 1.29E-22 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFE_1033 b6f6985abadd5ee32c8c9d1c4442253f 204 SMART SM00857 52 193 3.4E-17 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFE_2286 489376b1382dd4d3718f51ecaa129319 181 SUPERFAMILY SSF52540 4 179 1.3E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2286 489376b1382dd4d3718f51ecaa129319 181 Gene3D G3DSA:3.40.50.300 7 145 1.2E-9 T 12-10-2018 AFE_2286 489376b1382dd4d3718f51ecaa129319 181 Gene3D G3DSA:3.30.63.10 37 90 1.2E-9 T 12-10-2018 AFE_1552 5d44c1c19fcfce1013a5215e19553a3e 814 TIGRFAM TIGR02470 sucr_synth: sucrose synthase 41 810 0.0 T 12-10-2018 IPR012820 Sucrose synthase, plant/cyanobacteria GO:0005985|GO:0016157 KEGG: 00500+2.4.1.13|MetaCyc: PWY-3801 AFE_1552 5d44c1c19fcfce1013a5215e19553a3e 814 Pfam PF00534 Glycosyl transferases group 1 569 737 1.5E-28 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1552 5d44c1c19fcfce1013a5215e19553a3e 814 SUPERFAMILY SSF53756 285 772 6.28E-48 T 12-10-2018 AFE_1552 5d44c1c19fcfce1013a5215e19553a3e 814 Pfam PF00862 Sucrose synthase 22 561 9.0E-200 T 12-10-2018 IPR000368 Sucrose synthase GO:0005985|GO:0016157 AFE_1552 5d44c1c19fcfce1013a5215e19553a3e 814 Gene3D G3DSA:3.10.450.330 22 154 1.3E-33 T 12-10-2018 AFE_1552 5d44c1c19fcfce1013a5215e19553a3e 814 Gene3D G3DSA:3.40.50.2000 535 762 1.4E-231 T 12-10-2018 AFE_1552 5d44c1c19fcfce1013a5215e19553a3e 814 Gene3D G3DSA:1.20.120.1230 156 282 1.5E-39 T 12-10-2018 AFE_1552 5d44c1c19fcfce1013a5215e19553a3e 814 Gene3D G3DSA:3.40.50.2000 287 803 1.4E-231 T 12-10-2018 AFE_3161 bd99afbdb4866aa9a9b76a75ef8cc457 331 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFE_3161 bd99afbdb4866aa9a9b76a75ef8cc457 331 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 146 173 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFE_3161 bd99afbdb4866aa9a9b76a75ef8cc457 331 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFE_3161 bd99afbdb4866aa9a9b76a75ef8cc457 331 Gene3D G3DSA:3.40.50.720 101 296 2.7E-125 T 12-10-2018 AFE_3161 bd99afbdb4866aa9a9b76a75ef8cc457 331 SUPERFAMILY SSF51735 101 297 1.28E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3161 bd99afbdb4866aa9a9b76a75ef8cc457 331 Gene3D G3DSA:3.40.50.720 7 320 2.7E-125 T 12-10-2018 AFE_3161 bd99afbdb4866aa9a9b76a75ef8cc457 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 327 1.4E-27 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFE_3161 bd99afbdb4866aa9a9b76a75ef8cc457 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 296 1.5E-56 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFE_3161 bd99afbdb4866aa9a9b76a75ef8cc457 331 SUPERFAMILY SSF52283 2 133 4.46E-35 T 12-10-2018 AFE_2414 502ed76d7da33b3b21c93b8860ec4f1a 93 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 5 83 1.2E-24 T 12-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system AFE_2414 502ed76d7da33b3b21c93b8860ec4f1a 93 Gene3D G3DSA:3.10.450.530 1 86 4.8E-20 T 12-10-2018 IPR038573 Ribonuclease toxin BrnT superfamily AFE_2899 8687160361a10c6972b2cbf25e05687b 322 Gene3D G3DSA:1.10.600.10 1 322 3.1E-103 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFE_2899 8687160361a10c6972b2cbf25e05687b 322 SUPERFAMILY SSF48576 5 321 2.24E-89 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFE_2899 8687160361a10c6972b2cbf25e05687b 322 Pfam PF00348 Polyprenyl synthetase 32 264 2.8E-69 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFE_1731 73f28bb8e05fd3b06d2f2643e7a09fb2 446 SUPERFAMILY SSF56317 256 443 3.66E-14 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFE_1731 73f28bb8e05fd3b06d2f2643e7a09fb2 446 Pfam PF00795 Carbon-nitrogen hydrolase 356 445 1.6E-4 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFE_1688 f3133ee93c1cfa3c268a835f4e9b65fe 533 Gene3D G3DSA:1.20.120.1310 54 160 1.0E-41 T 12-10-2018 AFE_1688 f3133ee93c1cfa3c268a835f4e9b65fe 533 TIGRFAM TIGR02701 shell_carb_anhy: carboxysome shell carbonic anhydrase 67 512 1.2E-236 T 12-10-2018 IPR014074 Carboxysome shell carbonic anhydrase AFE_1688 f3133ee93c1cfa3c268a835f4e9b65fe 533 Pfam PF08936 Carboxysome Shell Carbonic Anhydrase 67 521 1.5E-204 T 12-10-2018 IPR014074 Carboxysome shell carbonic anhydrase AFE_1688 f3133ee93c1cfa3c268a835f4e9b65fe 533 Gene3D G3DSA:3.30.1330.140 408 524 6.7E-51 T 12-10-2018 AFE_1067 d38fa8aa033683c40bd3c1ffed47db92 559 Pfam PF06122 Conjugative relaxosome accessory transposon protein 38 456 6.3E-46 T 12-10-2018 IPR010927 Type IV conjugative transfer system protein TraH AFE_0969 4eee9676ce0f3c14b58367f1bdb599ae 377 Pfam PF16074 Type IV Pilus-assembly protein W 239 371 6.5E-21 T 12-10-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 AFE_0969 4eee9676ce0f3c14b58367f1bdb599ae 377 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 30 4.5E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFE_0969 4eee9676ce0f3c14b58367f1bdb599ae 377 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 31 2.0E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFE_2737 5ab9560a04798c2f19e35194c553fc2f 94 SUPERFAMILY SSF75471 1 89 5.49E-25 T 12-10-2018 IPR035920 YhbY-like superfamily AFE_2737 5ab9560a04798c2f19e35194c553fc2f 94 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 10 92 6.0E-15 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFE_2737 5ab9560a04798c2f19e35194c553fc2f 94 SMART SM01103 2 85 1.3E-31 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFE_2737 5ab9560a04798c2f19e35194c553fc2f 94 Gene3D G3DSA:3.30.110.60 1 94 8.2E-30 T 12-10-2018 IPR035920 YhbY-like superfamily AFE_2737 5ab9560a04798c2f19e35194c553fc2f 94 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 85 1.1E-19 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFE_0724 2ed28ad9b10202cb3b720aeb9c94c088 321 PIRSF PIRSF005211 4 320 8.8E-101 T 12-10-2018 IPR012020 AB hydrolase 4 family AFE_0724 2ed28ad9b10202cb3b720aeb9c94c088 321 Pfam PF00561 alpha/beta hydrolase fold 59 299 1.9E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFE_0724 2ed28ad9b10202cb3b720aeb9c94c088 321 SUPERFAMILY SSF53474 18 319 4.19E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_0724 2ed28ad9b10202cb3b720aeb9c94c088 321 Gene3D G3DSA:3.40.50.1820 38 308 2.2E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_3265 b4ee31cbe023f701c2df8b6f0d3031a5 476 PIRSF PIRSF001892 3 475 1.2E-81 T 12-10-2018 IPR028351 Cyclolysin transport protein CyaE GO:0005215 AFE_3265 b4ee31cbe023f701c2df8b6f0d3031a5 476 Gene3D G3DSA:1.20.1600.10 41 474 8.7E-83 T 12-10-2018 AFE_3265 b4ee31cbe023f701c2df8b6f0d3031a5 476 Pfam PF02321 Outer membrane efflux protein 76 260 1.6E-26 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_3265 b4ee31cbe023f701c2df8b6f0d3031a5 476 Pfam PF02321 Outer membrane efflux protein 287 468 3.5E-31 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_3265 b4ee31cbe023f701c2df8b6f0d3031a5 476 SUPERFAMILY SSF56954 45 470 6.41E-79 T 12-10-2018 AFE_1431 dfd76872619ca34c21fb3150c1358180 78 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.7E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_1431 dfd76872619ca34c21fb3150c1358180 78 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.7E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_1431 dfd76872619ca34c21fb3150c1358180 78 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.7E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_1431 dfd76872619ca34c21fb3150c1358180 78 SMART SM00422 1 70 4.2E-21 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_1431 dfd76872619ca34c21fb3150c1358180 78 Pfam PF13411 MerR HTH family regulatory protein 1 68 3.3E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_1431 dfd76872619ca34c21fb3150c1358180 78 SUPERFAMILY SSF46955 1 73 5.86E-22 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFE_1431 dfd76872619ca34c21fb3150c1358180 78 Gene3D G3DSA:1.10.1660.10 2 78 9.6E-24 T 12-10-2018 AFE_2928 ad170bf3de9c97297731d55381ea4101 287 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 240 274 0.023 T 12-10-2018 IPR001330 PFTB repeat GO:0003824 AFE_2928 ad170bf3de9c97297731d55381ea4101 287 SUPERFAMILY SSF48239 4 269 6.81E-12 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AFE_2641 5417143a0d4ba5ba8ba5f7e36813d1ad 113 SMART SM00418 8 86 2.4E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2641 5417143a0d4ba5ba8ba5f7e36813d1ad 113 Pfam PF12840 Helix-turn-helix domain 7 62 2.8E-13 T 12-10-2018 AFE_2641 5417143a0d4ba5ba8ba5f7e36813d1ad 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 8.2E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2641 5417143a0d4ba5ba8ba5f7e36813d1ad 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 8.2E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2641 5417143a0d4ba5ba8ba5f7e36813d1ad 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 8.2E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2641 5417143a0d4ba5ba8ba5f7e36813d1ad 113 Gene3D G3DSA:1.10.10.10 2 107 3.8E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2641 5417143a0d4ba5ba8ba5f7e36813d1ad 113 SUPERFAMILY SSF46785 6 101 5.81E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1742 aa2bc9a1f03d2a313ce9f3e0e657b88c 506 Pfam PF00171 Aldehyde dehydrogenase family 27 493 2.9E-161 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFE_1742 aa2bc9a1f03d2a313ce9f3e0e657b88c 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFE_1742 aa2bc9a1f03d2a313ce9f3e0e657b88c 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFE_1742 aa2bc9a1f03d2a313ce9f3e0e657b88c 506 Gene3D G3DSA:3.40.605.10 23 492 4.3E-161 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFE_1742 aa2bc9a1f03d2a313ce9f3e0e657b88c 506 Gene3D G3DSA:3.40.309.10 266 464 4.3E-161 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFE_1742 aa2bc9a1f03d2a313ce9f3e0e657b88c 506 SUPERFAMILY SSF53720 15 498 6.41E-160 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFE_2545 6c740b2f752a9717b189ceb7b093ffa9 356 SUPERFAMILY SSF55681 8 252 4.97E-56 T 12-10-2018 AFE_2545 6c740b2f752a9717b189ceb7b093ffa9 356 Gene3D G3DSA:3.30.390.50 262 352 8.4E-17 T 12-10-2018 AFE_2545 6c740b2f752a9717b189ceb7b093ffa9 356 Gene3D G3DSA:3.30.930.10 8 257 5.2E-50 T 12-10-2018 AFE_1961 d8a903354d6586ab9afa156783107793 412 SUPERFAMILY SSF103473 6 391 7.59E-29 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_1961 d8a903354d6586ab9afa156783107793 412 Pfam PF07690 Major Facilitator Superfamily 33 335 7.0E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_1961 d8a903354d6586ab9afa156783107793 412 Gene3D G3DSA:1.20.1250.20 6 392 6.0E-20 T 12-10-2018 AFE_2509 dd127938a570cc70178a09a58cb071b7 160 SMART SM00422 4 72 2.2E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_2509 dd127938a570cc70178a09a58cb071b7 160 SUPERFAMILY SSF46955 4 117 2.75E-23 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFE_2509 dd127938a570cc70178a09a58cb071b7 160 Pfam PF13411 MerR HTH family regulatory protein 5 68 1.2E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_2509 dd127938a570cc70178a09a58cb071b7 160 Gene3D G3DSA:1.10.1660.10 1 139 8.8E-26 T 12-10-2018 AFE_1202 d917a772ca9aa90cecd7ec7c0313b305 722 Pfam PF00665 Integrase core domain 279 419 7.9E-21 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFE_1202 d917a772ca9aa90cecd7ec7c0313b305 722 SUPERFAMILY SSF53098 280 471 3.03E-10 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_1202 d917a772ca9aa90cecd7ec7c0313b305 722 Gene3D G3DSA:3.30.420.10 273 484 2.9E-20 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_1202 d917a772ca9aa90cecd7ec7c0313b305 722 Pfam PF09299 Mu transposase, C-terminal 511 571 2.5E-8 T 12-10-2018 IPR015378 Transposase-like, Mu, C-terminal AFE_0716 700bc694ec1322fb884977eb0d6b549f 352 Pfam PF00586 AIR synthase related protein, N-terminal domain 66 166 7.2E-17 T 12-10-2018 IPR016188 PurM-like, N-terminal domain AFE_0716 700bc694ec1322fb884977eb0d6b549f 352 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 328 5.4E-25 T 12-10-2018 IPR010918 PurM-like, C-terminal domain AFE_0716 700bc694ec1322fb884977eb0d6b549f 352 Gene3D G3DSA:3.90.650.10 173 352 5.8E-55 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFE_0716 700bc694ec1322fb884977eb0d6b549f 352 SUPERFAMILY SSF55326 19 170 8.55E-30 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFE_0716 700bc694ec1322fb884977eb0d6b549f 352 SUPERFAMILY SSF56042 175 348 5.83E-44 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFE_0716 700bc694ec1322fb884977eb0d6b549f 352 Gene3D G3DSA:3.30.1330.10 18 171 2.4E-48 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFE_0716 700bc694ec1322fb884977eb0d6b549f 352 PIRSF PIRSF005644 13 352 1.6E-114 T 12-10-2018 IPR011854 Carbamoyl dehydratase HypE AFE_0716 700bc694ec1322fb884977eb0d6b549f 352 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 17 352 1.5E-127 T 12-10-2018 IPR011854 Carbamoyl dehydratase HypE AFE_3138 e17c2e0c36b5dc2ead18f61936f3250d 213 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 93 193 1.7E-16 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 AFE_3138 e17c2e0c36b5dc2ead18f61936f3250d 213 SMART SM00702 12 193 5.4E-34 T 12-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 AFE_3138 e17c2e0c36b5dc2ead18f61936f3250d 213 Gene3D G3DSA:2.60.120.620 7 193 8.4E-46 T 12-10-2018 AFE_0813 b15d4e995143df2136db4829d86afc22 465 Pfam PF07690 Major Facilitator Superfamily 27 360 7.9E-43 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_0813 b15d4e995143df2136db4829d86afc22 465 Gene3D G3DSA:1.20.1250.20 7 397 1.1E-84 T 12-10-2018 AFE_0813 b15d4e995143df2136db4829d86afc22 465 SUPERFAMILY SSF103473 11 398 1.96E-60 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_0813 b15d4e995143df2136db4829d86afc22 465 Gene3D G3DSA:3.30.70.100 398 462 3.7E-10 T 12-10-2018 AFE_0180 cdbcbb0590c0eec58bc56e49a41a6562 162 Gene3D G3DSA:3.10.50.40 3 154 3.0E-57 T 12-10-2018 AFE_0180 cdbcbb0590c0eec58bc56e49a41a6562 162 SUPERFAMILY SSF54534 3 140 1.87E-36 T 12-10-2018 AFE_0180 cdbcbb0590c0eec58bc56e49a41a6562 162 Gene3D G3DSA:2.40.10.330 71 121 3.0E-57 T 12-10-2018 AFE_0180 cdbcbb0590c0eec58bc56e49a41a6562 162 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 136 9.0E-14 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain AFE_0419 eb05d6c9873edcc2da475c381439a92f 363 SUPERFAMILY SSF51569 6 359 1.59E-65 T 12-10-2018 AFE_0419 eb05d6c9873edcc2da475c381439a92f 363 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 16 357 1.7E-73 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 AFE_0419 eb05d6c9873edcc2da475c381439a92f 363 ProSitePatterns PS01054 Transaldolase signature 1. 42 50 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 AFE_0419 eb05d6c9873edcc2da475c381439a92f 363 Hamap MF_00493 Transaldolase [tal]. 1 363 124.933 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AFE_0419 eb05d6c9873edcc2da475c381439a92f 363 TIGRFAM TIGR00876 tal_mycobact: transaldolase 14 357 4.7E-85 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AFE_0419 eb05d6c9873edcc2da475c381439a92f 363 PIRSF PIRSF036915 1 362 2.0E-126 T 12-10-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AFE_0419 eb05d6c9873edcc2da475c381439a92f 363 Gene3D G3DSA:3.20.20.70 3 362 8.0E-132 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2612 ec632634152dde63b7fdb32cf2db2582 65 Pfam PF01632 Ribosomal protein L35 2 62 7.6E-25 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2612 ec632634152dde63b7fdb32cf2db2582 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2612 ec632634152dde63b7fdb32cf2db2582 65 Gene3D G3DSA:2.40.50.530 1 64 7.0E-22 T 12-10-2018 AFE_2612 ec632634152dde63b7fdb32cf2db2582 65 SUPERFAMILY SSF143034 2 64 3.66E-24 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2612 ec632634152dde63b7fdb32cf2db2582 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.072 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFE_2612 ec632634152dde63b7fdb32cf2db2582 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 8.8E-21 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFE_2612 ec632634152dde63b7fdb32cf2db2582 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 8.8E-21 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFE_2612 ec632634152dde63b7fdb32cf2db2582 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 8.8E-21 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFE_2612 ec632634152dde63b7fdb32cf2db2582 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 2.1E-25 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFE_1566 61c45681b06d5877146826a288d8eaee 286 Pfam PF01695 IstB-like ATP binding protein 128 254 2.4E-19 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 AFE_1566 61c45681b06d5877146826a288d8eaee 286 SMART SM00382 129 261 7.9E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1566 61c45681b06d5877146826a288d8eaee 286 Gene3D G3DSA:3.40.50.300 78 257 1.1E-36 T 12-10-2018 AFE_1566 61c45681b06d5877146826a288d8eaee 286 SUPERFAMILY SSF52540 107 246 8.13E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2920 2144204d58d0b7f4ed7772e44a53e53a 99 Pfam PF14373 Superinfection immunity protein 36 77 1.2E-16 T 12-10-2018 IPR016410 Bacteriophage-associated immunity protein AFE_2920 2144204d58d0b7f4ed7772e44a53e53a 99 ProDom PD028561 MEMBRANE IMMUNITY SUPERINFECTION GP66 PROTEIN IMM GP75 IMM RB69 INTEGRAL 32 66 0.001 T 12-10-2018 IPR016410 Bacteriophage-associated immunity protein AFE_0126 765ea2521413c0eafaaec494c8d5e54f 119 Gene3D G3DSA:3.30.1130.10 1 118 5.9E-39 T 12-10-2018 AFE_0126 765ea2521413c0eafaaec494c8d5e54f 119 SMART SM00905 4 114 2.4E-43 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFE_0126 765ea2521413c0eafaaec494c8d5e54f 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 4 114 2.5E-26 T 12-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFE_0126 765ea2521413c0eafaaec494c8d5e54f 119 TIGRFAM TIGR00526 folB_dom: FolB domain 1 117 6.1E-31 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFE_0126 765ea2521413c0eafaaec494c8d5e54f 119 SUPERFAMILY SSF55620 1 114 8.9E-35 T 12-10-2018 AFE_0126 765ea2521413c0eafaaec494c8d5e54f 119 Pfam PF02152 Dihydroneopterin aldolase 4 113 1.4E-31 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFE_0987 c71b92fa82b957ec76ee4e4e529732e1 286 Gene3D G3DSA:1.10.150.650 103 174 1.4E-78 T 12-10-2018 AFE_0987 c71b92fa82b957ec76ee4e4e529732e1 286 Gene3D G3DSA:3.20.20.140 10 255 1.4E-78 T 12-10-2018 AFE_0987 c71b92fa82b957ec76ee4e4e529732e1 286 SUPERFAMILY SSF89550 10 279 6.67E-51 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFE_0987 c71b92fa82b957ec76ee4e4e529732e1 286 Pfam PF02811 PHP domain 11 77 7.2E-8 T 12-10-2018 IPR004013 PHP domain GO:0003824 AFE_0987 c71b92fa82b957ec76ee4e4e529732e1 286 SMART SM00481 10 75 4.3E-18 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFE_0671 6630812773948fb30592ab1e81f3dc96 249 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 1.9E-75 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 AFE_0671 6630812773948fb30592ab1e81f3dc96 249 PIRSF PIRSF000441 1 224 1.4E-86 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 AFE_0671 6630812773948fb30592ab1e81f3dc96 249 SUPERFAMILY SSF51161 4 170 4.02E-56 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily AFE_0671 6630812773948fb30592ab1e81f3dc96 249 Pfam PF06426 Serine acetyltransferase, N-terminal 5 35 1.7E-4 T 12-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 AFE_0671 6630812773948fb30592ab1e81f3dc96 249 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 150 1.1E-7 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_0671 6630812773948fb30592ab1e81f3dc96 249 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 1.2E-5 T 12-10-2018 IPR001451 Hexapeptide repeat AFE_0671 6630812773948fb30592ab1e81f3dc96 249 Gene3D G3DSA:1.10.3130.10 2 66 1.0E-22 T 12-10-2018 AFE_0671 6630812773948fb30592ab1e81f3dc96 249 Gene3D G3DSA:2.160.10.10 67 183 2.2E-37 T 12-10-2018 AFE_0671 6630812773948fb30592ab1e81f3dc96 249 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFE_0350 b30c4f9118711a16f7648495f066516d 37 SUPERFAMILY SSF57840 1 37 1.18E-16 T 12-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0350 b30c4f9118711a16f7648495f066516d 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.393 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0350 b30c4f9118711a16f7648495f066516d 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0350 b30c4f9118711a16f7648495f066516d 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 3.0E-8 T 12-10-2018 AFE_0350 b30c4f9118711a16f7648495f066516d 37 Pfam PF00444 Ribosomal protein L36 1 37 4.3E-19 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0350 b30c4f9118711a16f7648495f066516d 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.3E-22 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2715 8a6ffc5c199f7028a53296e949522417 145 Gene3D G3DSA:3.40.630.30 7 143 7.3E-23 T 12-10-2018 AFE_2715 8a6ffc5c199f7028a53296e949522417 145 SUPERFAMILY SSF55729 31 140 2.7E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_2715 8a6ffc5c199f7028a53296e949522417 145 Pfam PF00583 Acetyltransferase (GNAT) family 44 134 3.5E-14 T 12-10-2018 IPR000182 GNAT domain AFE_1081 51fbe620b8f6746ef17c7377d694a80d 543 Pfam PF03743 Bacterial conjugation TrbI-like protein 257 461 8.2E-27 T 12-10-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI AFE_2895 b17d15060e923be8688bcd769a380d8e 584 Gene3D G3DSA:3.40.710.10 285 465 4.0E-88 T 12-10-2018 AFE_2895 b17d15060e923be8688bcd769a380d8e 584 SUPERFAMILY SSF56601 174 559 2.73E-81 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_2895 b17d15060e923be8688bcd769a380d8e 584 SUPERFAMILY SSF56519 57 222 3.01E-35 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 AFE_2895 b17d15060e923be8688bcd769a380d8e 584 Pfam PF00905 Penicillin binding protein transpeptidase domain 248 544 4.1E-62 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFE_2895 b17d15060e923be8688bcd769a380d8e 584 Gene3D G3DSA:3.30.450.330 227 546 4.0E-88 T 12-10-2018 AFE_2895 b17d15060e923be8688bcd769a380d8e 584 Gene3D G3DSA:3.90.1310.30 53 222 7.9E-36 T 12-10-2018 AFE_2895 b17d15060e923be8688bcd769a380d8e 584 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 205 3.4E-13 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFE_2487 6f7e812ffaa0b056e248f2ce0e000f3c 108 SUPERFAMILY SSF46785 36 82 1.55E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1561 1d778820165425a505563989d890b176 284 Pfam PF11236 Protein of unknown function (DUF3037) 7 62 3.1E-7 T 12-10-2018 IPR021398 Protein of unknown function DUF3037 AFE_3222 5ea96ec6900cbb6ecf91bd7d133216bf 356 SUPERFAMILY SSF101478 1 349 4.84E-47 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AFE_3222 5ea96ec6900cbb6ecf91bd7d133216bf 356 Gene3D G3DSA:1.10.4080.10 1 355 1.1E-30 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AFE_3222 5ea96ec6900cbb6ecf91bd7d133216bf 356 Pfam PF03747 ADP-ribosylglycohydrolase 6 327 3.9E-53 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 AFE_2806 270e508d71938a5722a1e49cc9f62a4f 215 Gene3D G3DSA:3.10.620.30 2 160 1.1E-16 T 12-10-2018 AFE_2806 270e508d71938a5722a1e49cc9f62a4f 215 SUPERFAMILY SSF54001 36 145 1.82E-19 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFE_2806 270e508d71938a5722a1e49cc9f62a4f 215 Pfam PF01841 Transglutaminase-like superfamily 30 135 3.5E-15 T 12-10-2018 IPR002931 Transglutaminase-like AFE_1372 19cff2bc6fda8501f90a1e7c309362b0 388 Gene3D G3DSA:1.10.3290.10 22 296 2.0E-47 T 12-10-2018 IPR036597 Fido-like domain superfamily AFE_1372 19cff2bc6fda8501f90a1e7c309362b0 388 SUPERFAMILY SSF140931 86 286 1.16E-30 T 12-10-2018 IPR036597 Fido-like domain superfamily AFE_1372 19cff2bc6fda8501f90a1e7c309362b0 388 Pfam PF02661 Fic/DOC family 109 215 2.1E-19 T 12-10-2018 IPR003812 Fido domain AFE_1339 4ab0a006d435a3260d5c3f39d332b67b 377 Gene3D G3DSA:3.10.560.10 165 250 1.6E-12 T 12-10-2018 AFE_1339 4ab0a006d435a3260d5c3f39d332b67b 377 Gene3D G3DSA:3.30.1950.10 91 164 1.3E-19 T 12-10-2018 AFE_1339 4ab0a006d435a3260d5c3f39d332b67b 377 Pfam PF02563 Polysaccharide biosynthesis/export protein 86 167 1.1E-21 T 12-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 AFE_1339 4ab0a006d435a3260d5c3f39d332b67b 377 Gene3D G3DSA:3.10.560.10 251 341 4.6E-16 T 12-10-2018 AFE_2707 ca6398705404d8f559af41d7d11ab87d 161 Pfam PF07811 TadE-like protein 12 54 3.0E-12 T 12-10-2018 IPR012495 TadE-like AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 SUPERFAMILY SSF53098 298 485 2.14E-46 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 SMART SM00279 169 204 2.8E-13 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 Gene3D G3DSA:1.10.150.20 170 242 6.7E-90 T 12-10-2018 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 7 166 1.7E-50 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 Gene3D G3DSA:3.40.50.1010 7 271 6.7E-90 T 12-10-2018 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 TIGRFAM TIGR00593 pola: DNA polymerase I 7 898 2.3E-274 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 SMART SM00482 656 862 1.4E-114 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 Pfam PF01612 3'-5' exonuclease 299 484 9.2E-34 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 SUPERFAMILY SSF88723 5 166 2.07E-50 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 SUPERFAMILY SSF56672 492 898 3.89E-151 T 12-10-2018 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 Pfam PF00476 DNA polymerase family A 521 896 1.8E-149 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 SMART SM00475 1 257 4.0E-112 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 Gene3D G3DSA:1.20.1060.10 513 628 2.2E-40 T 12-10-2018 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 PRINTS PR00868 DNA-polymerase family A (pol I) signature 700 713 7.2E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 PRINTS PR00868 DNA-polymerase family A (pol I) signature 670 693 7.2E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 PRINTS PR00868 DNA-polymerase family A (pol I) signature 625 647 7.2E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 PRINTS PR00868 DNA-polymerase family A (pol I) signature 815 831 7.2E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 PRINTS PR00868 DNA-polymerase family A (pol I) signature 845 858 7.2E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 PRINTS PR00868 DNA-polymerase family A (pol I) signature 648 663 7.2E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 PRINTS PR00868 DNA-polymerase family A (pol I) signature 783 794 7.2E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 PRINTS PR00868 DNA-polymerase family A (pol I) signature 761 772 7.2E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 PRINTS PR00868 DNA-polymerase family A (pol I) signature 724 749 7.2E-77 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 SMART SM00474 299 487 3.2E-27 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 Gene3D G3DSA:1.10.150.20 679 822 3.4E-109 T 12-10-2018 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 SUPERFAMILY SSF47807 167 278 1.32E-31 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 Gene3D G3DSA:3.30.70.370 634 894 3.4E-109 T 12-10-2018 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 Gene3D G3DSA:3.30.420.10 296 511 7.8E-65 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_3094 6b2d2a38607aae198d7ca868abe7c4b1 899 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 167 251 1.7E-26 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 AFE_0004 d52977862d88c6e306d6a3df1b25541f 1168 Gene3D G3DSA:2.40.30.10 841 943 2.3E-9 T 12-10-2018 AFE_0004 d52977862d88c6e306d6a3df1b25541f 1168 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 555 573 3.6E-7 T 12-10-2018 AFE_0004 d52977862d88c6e306d6a3df1b25541f 1168 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 501 519 3.6E-7 T 12-10-2018 AFE_0004 d52977862d88c6e306d6a3df1b25541f 1168 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 388 407 3.6E-7 T 12-10-2018 AFE_0004 d52977862d88c6e306d6a3df1b25541f 1168 SUPERFAMILY SSF51971 385 729 1.02E-17 T 12-10-2018 AFE_0004 d52977862d88c6e306d6a3df1b25541f 1168 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 387 590 3.9E-9 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_0004 d52977862d88c6e306d6a3df1b25541f 1168 SUPERFAMILY SSF63380 844 943 1.0E-10 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFE_1550 441a5be0f3e8a21ab8fce9fb9e132f7d 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 26 50 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFE_1550 441a5be0f3e8a21ab8fce9fb9e132f7d 303 Gene3D G3DSA:3.40.1190.20 7 292 4.4E-69 T 12-10-2018 IPR029056 Ribokinase-like AFE_1550 441a5be0f3e8a21ab8fce9fb9e132f7d 303 Pfam PF00294 pfkB family carbohydrate kinase 23 286 4.2E-38 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB AFE_1550 441a5be0f3e8a21ab8fce9fb9e132f7d 303 SUPERFAMILY SSF53613 9 289 3.43E-51 T 12-10-2018 IPR029056 Ribokinase-like AFE_1809 7271f043af6d540873550335499d8372 499 Gene3D G3DSA:1.20.1250.20 35 493 6.5E-77 T 12-10-2018 AFE_1809 7271f043af6d540873550335499d8372 499 Pfam PF00083 Sugar (and other) transporter 76 492 1.9E-43 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 AFE_1809 7271f043af6d540873550335499d8372 499 ProSitePatterns PS00217 Sugar transport proteins signature 2. 138 163 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFE_1809 7271f043af6d540873550335499d8372 499 SUPERFAMILY SSF103473 22 492 4.58E-64 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_0963 306cf06a9a4b3095bdddd2e3b332954b 338 SUPERFAMILY SSF51735 1 278 6.79E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0963 306cf06a9a4b3095bdddd2e3b332954b 338 Pfam PF13460 NAD(P)H-binding 10 142 1.8E-17 T 12-10-2018 IPR016040 NAD(P)-binding domain AFE_0963 306cf06a9a4b3095bdddd2e3b332954b 338 Gene3D G3DSA:3.40.50.720 4 284 4.3E-47 T 12-10-2018 AFE_1556 60d01e577d5594ef228a4b2b8e96ce58 331 Gene3D G3DSA:1.10.443.10 235 313 2.5E-22 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_1556 60d01e577d5594ef228a4b2b8e96ce58 331 SUPERFAMILY SSF56349 61 306 5.59E-49 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_1556 60d01e577d5594ef228a4b2b8e96ce58 331 Pfam PF00589 Phage integrase family 160 224 4.6E-5 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_1556 60d01e577d5594ef228a4b2b8e96ce58 331 Pfam PF00589 Phage integrase family 238 302 1.1E-16 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_1556 60d01e577d5594ef228a4b2b8e96ce58 331 Gene3D G3DSA:1.10.443.10 152 233 1.5E-11 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_0215 438d1457893aea9ab771edb566aad1e0 151 SUPERFAMILY SSF89447 1 138 1.99E-43 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFE_0215 438d1457893aea9ab771edb566aad1e0 151 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 130 4.0E-34 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AFE_0215 438d1457893aea9ab771edb566aad1e0 151 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 151 52.034 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AFE_0215 438d1457893aea9ab771edb566aad1e0 151 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 131 1.4E-40 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 AFE_0215 438d1457893aea9ab771edb566aad1e0 151 Pfam PF02381 MraZ protein, putative antitoxin-like 84 135 8.4E-14 T 12-10-2018 IPR020603 MraZ domain AFE_0215 438d1457893aea9ab771edb566aad1e0 151 Pfam PF02381 MraZ protein, putative antitoxin-like 1 79 2.4E-15 T 12-10-2018 IPR020603 MraZ domain AFE_0215 438d1457893aea9ab771edb566aad1e0 151 Gene3D G3DSA:2.40.330.20 1 140 8.2E-44 T 12-10-2018 IPR038619 MraZ superfamily AFE_0229 519fa05ccb70f391e8ba9a70356af438 238 Gene3D G3DSA:3.20.20.370 2 226 2.6E-54 T 12-10-2018 AFE_0229 519fa05ccb70f391e8ba9a70356af438 238 SUPERFAMILY SSF88713 22 214 6.39E-34 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFE_0229 519fa05ccb70f391e8ba9a70356af438 238 Pfam PF01522 Polysaccharide deacetylase 57 194 6.0E-26 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFE_2365 436b29e444582ad8c68ae625615c3694 73 Pfam PF11127 Protein of unknown function (DUF2892) 2 60 3.2E-13 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 AFE_3239 96b9cb6f6e780b6bfc51eb62096fcc42 208 SUPERFAMILY SSF47240 40 121 2.63E-15 T 12-10-2018 IPR009078 Ferritin-like superfamily AFE_3239 96b9cb6f6e780b6bfc51eb62096fcc42 208 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 48 208 1.4E-43 T 12-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 AFE_3239 96b9cb6f6e780b6bfc51eb62096fcc42 208 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 7 208 26.496 T 12-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 AFE_3048 ac3926d94f18720d90682483628ca2e0 72 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 48 2.5E-21 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFE_3048 ac3926d94f18720d90682483628ca2e0 72 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 71 21.584 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFE_3048 ac3926d94f18720d90682483628ca2e0 72 Pfam PF02416 mttA/Hcf106 family 5 51 1.8E-14 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AFE_2181 7296655a0d6a14c4386646c18992f809 188 SUPERFAMILY SSF89155 26 177 2.88E-23 T 12-10-2018 IPR036411 TorD-like superfamily AFE_2181 7296655a0d6a14c4386646c18992f809 188 Pfam PF02613 Nitrate reductase delta subunit 64 161 1.7E-12 T 12-10-2018 IPR020945 DMSO/Nitrate reductase chaperone AFE_2181 7296655a0d6a14c4386646c18992f809 188 Gene3D G3DSA:1.10.3480.10 16 185 1.8E-25 T 12-10-2018 AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 Gene3D G3DSA:2.60.40.4050 24 75 1.3E-8 T 12-10-2018 AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 SUPERFAMILY SSF101967 13 100 1.06E-17 T 12-10-2018 AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 Pfam PF05658 Head domain of trimeric autotransporter adhesin 568 594 2.0E-4 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 Pfam PF05658 Head domain of trimeric autotransporter adhesin 30 56 3.3E-6 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 Pfam PF05658 Head domain of trimeric autotransporter adhesin 545 566 1.3E-4 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 Pfam PF05658 Head domain of trimeric autotransporter adhesin 512 538 2.8E-4 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 Pfam PF05658 Head domain of trimeric autotransporter adhesin 498 524 1.8E-4 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 Pfam PF03895 YadA-like membrane anchor domain 649 706 2.2E-9 T 12-10-2018 IPR005594 YadA-like, C-terminal AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 Gene3D G3DSA:1.20.5.170 77 123 7.9E-11 T 12-10-2018 AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 Gene3D G3DSA:2.150.10.10 456 631 7.4E-35 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 SUPERFAMILY SSF101967 494 622 1.44E-25 T 12-10-2018 AFE_2684 68534559505a9da9607ca2d85c7da2d5 706 SUPERFAMILY SSF54523 612 706 1.88E-5 T 12-10-2018 AFE_1079 bfc320a95e5c836e17d0d392f06b65ed 204 Pfam PF05309 TraE protein 2 180 1.2E-43 T 12-10-2018 IPR007973 Pilus assembly TraE GO:0000746 AFE_1079 bfc320a95e5c836e17d0d392f06b65ed 204 TIGRFAM TIGR02761 TraE_TIGR: type IV conjugative transfer system protein TraE 2 180 1.7E-60 T 12-10-2018 IPR007973 Pilus assembly TraE GO:0000746 AFE_3099 fbd6aa3a63847be0224ec2cfd1d29538 200 SUPERFAMILY SSF81342 12 199 3.84E-12 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFE_3099 fbd6aa3a63847be0224ec2cfd1d29538 200 Pfam PF01292 Prokaryotic cytochrome b561 20 190 2.7E-12 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFE_2991 6017ee815f3aa3923044fa36d72f1ad6 319 Gene3D G3DSA:1.10.3720.10 85 311 2.1E-14 T 12-10-2018 IPR035906 MetI-like superfamily AFE_2991 6017ee815f3aa3923044fa36d72f1ad6 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 318 2.4E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFE_2991 6017ee815f3aa3923044fa36d72f1ad6 319 SUPERFAMILY SSF161098 91 305 8.83E-12 T 12-10-2018 IPR035906 MetI-like superfamily AFE_2394 fc402cc092f6e61200b39ee26b6807b0 116 Pfam PF13565 Homeodomain-like domain 12 65 2.2E-9 T 12-10-2018 AFE_3273 168ae5937958f7931cb5f3032664a788 151 Pfam PF07813 LTXXQ motif family protein 49 138 1.2E-5 T 12-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 AFE_3273 168ae5937958f7931cb5f3032664a788 151 Gene3D G3DSA:1.20.120.1490 45 143 1.2E-8 T 12-10-2018 AFE_0207 bdb95c2cf38c1064c40411518f1eebc9 390 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 15 372 4.1E-124 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_0207 bdb95c2cf38c1064c40411518f1eebc9 390 Pfam PF01098 Cell cycle protein 18 372 5.0E-99 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFE_1530 56850d310e8baa42a714cb306d2e43fd 72 Pfam PF00037 4Fe-4S binding domain 4 26 1.3E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_1530 56850d310e8baa42a714cb306d2e43fd 72 Gene3D G3DSA:3.30.70.20 3 71 1.4E-22 T 12-10-2018 AFE_1530 56850d310e8baa42a714cb306d2e43fd 72 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_1530 56850d310e8baa42a714cb306d2e43fd 72 SUPERFAMILY SSF54862 5 63 1.07E-14 T 12-10-2018 AFE_0454 b624a7a05612004ad0cdf1e38440c3ab 418 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 6 417 40.983 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_0454 b624a7a05612004ad0cdf1e38440c3ab 418 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 324 345 - T 12-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_0454 b624a7a05612004ad0cdf1e38440c3ab 418 Pfam PF00171 Aldehyde dehydrogenase family 312 374 2.0E-7 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFE_0454 b624a7a05612004ad0cdf1e38440c3ab 418 Pfam PF00171 Aldehyde dehydrogenase family 6 283 1.3E-16 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFE_0454 b624a7a05612004ad0cdf1e38440c3ab 418 SUPERFAMILY SSF53720 5 417 2.62E-118 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFE_0454 b624a7a05612004ad0cdf1e38440c3ab 418 Gene3D G3DSA:3.40.309.10 227 375 1.1E-157 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFE_0454 b624a7a05612004ad0cdf1e38440c3ab 418 Gene3D G3DSA:3.40.605.10 19 412 1.1E-157 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFE_0454 b624a7a05612004ad0cdf1e38440c3ab 418 PIRSF PIRSF000151 1 418 4.0E-170 T 12-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AFE_0454 b624a7a05612004ad0cdf1e38440c3ab 418 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 14 405 4.3E-138 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFE_3063 dcb3b02a6a181ebdb89f4ec57638f89f 312 Gene3D G3DSA:3.40.50.20 9 113 3.3E-105 T 12-10-2018 AFE_3063 dcb3b02a6a181ebdb89f4ec57638f89f 312 Gene3D G3DSA:3.30.1490.20 136 200 3.3E-105 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFE_3063 dcb3b02a6a181ebdb89f4ec57638f89f 312 Gene3D G3DSA:3.30.470.20 114 294 3.3E-105 T 12-10-2018 AFE_3063 dcb3b02a6a181ebdb89f4ec57638f89f 312 SUPERFAMILY SSF52440 4 121 1.96E-37 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFE_3063 dcb3b02a6a181ebdb89f4ec57638f89f 312 SUPERFAMILY SSF56059 122 310 5.11E-52 T 12-10-2018 AFE_3063 dcb3b02a6a181ebdb89f4ec57638f89f 312 TIGRFAM TIGR01380 glut_syn: glutathione synthase 4 310 1.7E-116 T 12-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AFE_3063 dcb3b02a6a181ebdb89f4ec57638f89f 312 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 123 295 1.7E-67 T 12-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AFE_3063 dcb3b02a6a181ebdb89f4ec57638f89f 312 Hamap MF_00162 Glutathione synthetase [gshB]. 1 312 144.685 T 12-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AFE_3063 dcb3b02a6a181ebdb89f4ec57638f89f 312 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 4 119 4.5E-37 T 12-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 AFE_0082 92c034a3946e1c95eee0abfd66be298e 308 SUPERFAMILY SSF53448 4 224 1.78E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0082 92c034a3946e1c95eee0abfd66be298e 308 Pfam PF13641 Glycosyltransferase like family 2 5 221 1.0E-17 T 12-10-2018 AFE_0082 92c034a3946e1c95eee0abfd66be298e 308 Gene3D G3DSA:3.90.550.10 1 222 3.0E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2983 1899bb522f8357611d872dd7ec1685ef 80 Gene3D G3DSA:3.40.1620.10 5 42 1.7E-11 T 12-10-2018 AFE_2983 1899bb522f8357611d872dd7ec1685ef 80 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 6 46 8.6E-15 T 12-10-2018 AFE_2983 1899bb522f8357611d872dd7ec1685ef 80 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 45 2.7E-14 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM AFE_2983 1899bb522f8357611d872dd7ec1685ef 80 SUPERFAMILY SSF143120 7 45 7.46E-11 T 12-10-2018 IPR036165 YefM-like superfamily AFE_2768 8ba045e171a85d884a3eb973a5a6ccc7 126 SUPERFAMILY SSF53098 27 85 2.85E-7 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_0864 b5e4596714d4c2736c80fc4220cb5d7e 514 SUPERFAMILY SSF103473 18 494 5.23E-41 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_0864 b5e4596714d4c2736c80fc4220cb5d7e 514 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 488 1.2E-79 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFE_0864 b5e4596714d4c2736c80fc4220cb5d7e 514 Pfam PF07690 Major Facilitator Superfamily 27 411 4.8E-33 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_0864 b5e4596714d4c2736c80fc4220cb5d7e 514 Gene3D G3DSA:1.20.1250.20 276 500 3.1E-6 T 12-10-2018 AFE_0864 b5e4596714d4c2736c80fc4220cb5d7e 514 Gene3D G3DSA:1.20.1720.10 22 222 2.8E-33 T 12-10-2018 AFE_0076 d05753cc090370a6867322db22c7f731 499 Pfam PF13440 Polysaccharide biosynthesis protein 36 325 5.4E-20 T 12-10-2018 AFE_0076 d05753cc090370a6867322db22c7f731 499 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 343 441 4.6E-7 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain AFE_1652 cf1a7f48524af6ad525b929bdf54bb5c 755 Gene3D G3DSA:3.40.50.740 121 551 9.0E-76 T 12-10-2018 AFE_1652 cf1a7f48524af6ad525b929bdf54bb5c 755 Pfam PF01568 Molydopterin dinucleotide binding domain 637 726 7.7E-9 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFE_1652 cf1a7f48524af6ad525b929bdf54bb5c 755 SUPERFAMILY SSF50692 637 750 7.46E-16 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFE_1652 cf1a7f48524af6ad525b929bdf54bb5c 755 PIRSF PIRSF000144 1 754 0.0 T 12-10-2018 AFE_1652 cf1a7f48524af6ad525b929bdf54bb5c 755 SUPERFAMILY SSF53706 48 621 1.09E-148 T 12-10-2018 AFE_1652 cf1a7f48524af6ad525b929bdf54bb5c 755 Pfam PF00384 Molybdopterin oxidoreductase 109 550 3.7E-34 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_1652 cf1a7f48524af6ad525b929bdf54bb5c 755 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 13 748 1.8E-286 T 12-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 AFE_1652 cf1a7f48524af6ad525b929bdf54bb5c 755 Gene3D G3DSA:3.40.228.10 181 393 9.0E-76 T 12-10-2018 AFE_1098 55e8dfeb9586ec07c608a25dff32b412 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 49 1.1E-8 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_1098 55e8dfeb9586ec07c608a25dff32b412 79 SMART SM00966 6 51 1.2E-7 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_1098 55e8dfeb9586ec07c608a25dff32b412 79 Gene3D G3DSA:2.10.260.10 1 78 2.6E-24 T 12-10-2018 AFE_1098 55e8dfeb9586ec07c608a25dff32b412 79 SUPERFAMILY SSF89447 1 72 1.31E-16 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFE_0892 01416ab28ff4e3f40893e0429971ab45 407 Gene3D G3DSA:2.30.130.10 5 79 1.8E-17 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 AFE_0892 01416ab28ff4e3f40893e0429971ab45 407 Gene3D G3DSA:3.40.50.150 187 400 1.2E-66 T 12-10-2018 AFE_0892 01416ab28ff4e3f40893e0429971ab45 407 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 175 355 1.3E-18 T 12-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 AFE_0892 01416ab28ff4e3f40893e0429971ab45 407 Gene3D G3DSA:3.30.750.80 81 186 2.5E-31 T 12-10-2018 AFE_0892 01416ab28ff4e3f40893e0429971ab45 407 SUPERFAMILY SSF88697 8 78 1.86E-8 T 12-10-2018 IPR015947 PUA-like superfamily AFE_0892 01416ab28ff4e3f40893e0429971ab45 407 SUPERFAMILY SSF53335 88 392 8.23E-70 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_1651 d877f4c675df196d22c44b4947bd339d 293 Gene3D G3DSA:1.10.1040.10 161 292 1.5E-32 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFE_1651 d877f4c675df196d22c44b4947bd339d 293 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFE_1651 d877f4c675df196d22c44b4947bd339d 293 SUPERFAMILY SSF51735 1 158 2.68E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_1651 d877f4c675df196d22c44b4947bd339d 293 PIRSF PIRSF000103 1 291 6.6E-71 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFE_1651 d877f4c675df196d22c44b4947bd339d 293 Gene3D G3DSA:3.40.50.720 1 160 2.2E-44 T 12-10-2018 AFE_1651 d877f4c675df196d22c44b4947bd339d 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 157 4.1E-35 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFE_1651 d877f4c675df196d22c44b4947bd339d 293 SUPERFAMILY SSF48179 166 290 1.07E-26 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFE_1651 d877f4c675df196d22c44b4947bd339d 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 281 1.2E-17 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFE_1553 1d0fcca3a023a07fb06106fe5f6b1dbd 174 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 91 170 1.7E-33 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFE_1553 1d0fcca3a023a07fb06106fe5f6b1dbd 174 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 14 88 3.7E-4 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFE_1553 1d0fcca3a023a07fb06106fe5f6b1dbd 174 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 141 147 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFE_1553 1d0fcca3a023a07fb06106fe5f6b1dbd 174 SUPERFAMILY SSF46767 90 171 2.75E-30 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 AFE_1553 1d0fcca3a023a07fb06106fe5f6b1dbd 174 SUPERFAMILY SSF53155 12 95 5.1E-6 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFE_1553 1d0fcca3a023a07fb06106fe5f6b1dbd 174 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 92 171 5.3E-31 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFE_1553 1d0fcca3a023a07fb06106fe5f6b1dbd 174 Gene3D G3DSA:1.10.10.10 90 173 5.7E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0095 bbbee7f91572d82cc9a2a86260a641a6 57 Gene3D G3DSA:1.10.8.550 6 57 2.2E-17 T 12-10-2018 AFE_0095 bbbee7f91572d82cc9a2a86260a641a6 57 Pfam PF08369 Proto-chlorophyllide reductase 57 kD subunit 8 51 7.1E-17 T 12-10-2018 IPR013580 Proto-chlorophyllide/chlorophyllide reductase, C-terminal GO:0015979|GO:0015995|GO:0016491|GO:0055114 KEGG: 00860+1.3.7.7|MetaCyc: PWY-5531|MetaCyc: PWY-7159 AFE_2349 efbc6b368e1fa4ad6d583bf5557a387c 561 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 61 543 2.7E-127 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFE_2349 efbc6b368e1fa4ad6d583bf5557a387c 561 Pfam PF07690 Major Facilitator Superfamily 66 459 6.3E-57 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_2349 efbc6b368e1fa4ad6d583bf5557a387c 561 Gene3D G3DSA:1.20.1250.20 308 485 1.3E-13 T 12-10-2018 AFE_2349 efbc6b368e1fa4ad6d583bf5557a387c 561 SUPERFAMILY SSF103473 45 545 1.7E-64 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_2349 efbc6b368e1fa4ad6d583bf5557a387c 561 Gene3D G3DSA:1.20.1720.10 62 269 4.2E-49 T 12-10-2018 AFE_0238 13ba7a5067b3c182fdf7a5dfce8d98c2 302 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 11 292 4.2E-62 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AFE_0238 13ba7a5067b3c182fdf7a5dfce8d98c2 302 PIRSF PIRSF026649 3 302 3.3E-84 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AFE_1141 513a11197d3a2ca4c9210362bb0df9cd 292 Pfam PF13421 SPFH domain-Band 7 family 34 231 1.7E-10 T 12-10-2018 IPR033880 SPFH domain, YdjI-like AFE_0733 295d58cf2a70d85b6ae0b0c1a85d6c53 364 Gene3D G3DSA:3.40.50.1970 1 172 9.8E-65 T 12-10-2018 AFE_0733 295d58cf2a70d85b6ae0b0c1a85d6c53 364 PIRSF PIRSF001455 6 361 1.0E-110 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFE_0733 295d58cf2a70d85b6ae0b0c1a85d6c53 364 Gene3D G3DSA:1.20.1090.10 173 361 8.4E-69 T 12-10-2018 AFE_0733 295d58cf2a70d85b6ae0b0c1a85d6c53 364 Pfam PF01761 3-dehydroquinate synthase 67 324 6.2E-107 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFE_0733 295d58cf2a70d85b6ae0b0c1a85d6c53 364 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 353 1.8E-117 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFE_0733 295d58cf2a70d85b6ae0b0c1a85d6c53 364 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 355 71.588 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFE_0733 295d58cf2a70d85b6ae0b0c1a85d6c53 364 SUPERFAMILY SSF56796 6 356 2.22E-117 T 12-10-2018 AFE_1540 c79305dc90c93235b7247d4faeccfeae 380 SUPERFAMILY SSF53383 6 369 6.46E-83 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_1540 c79305dc90c93235b7247d4faeccfeae 380 PIRSF PIRSF000390 1 373 5.2E-85 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFE_1540 c79305dc90c93235b7247d4faeccfeae 380 Gene3D G3DSA:3.40.640.10 2 245 1.3E-67 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_1540 c79305dc90c93235b7247d4faeccfeae 380 Gene3D G3DSA:3.90.1150.10 246 369 3.4E-24 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_1540 c79305dc90c93235b7247d4faeccfeae 380 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 366 1.3E-86 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFE_2790 634f2f6999acf33e5d88d6f92d6e14a2 1022 Gene3D G3DSA:3.40.50.300 265 459 2.6E-47 T 12-10-2018 AFE_2790 634f2f6999acf33e5d88d6f92d6e14a2 1022 Gene3D G3DSA:3.90.1570.50 104 260 5.4E-21 T 12-10-2018 AFE_2790 634f2f6999acf33e5d88d6f92d6e14a2 1022 SUPERFAMILY SSF52540 404 676 5.78E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2790 634f2f6999acf33e5d88d6f92d6e14a2 1022 SMART SM00487 267 474 1.4E-12 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_2790 634f2f6999acf33e5d88d6f92d6e14a2 1022 Pfam PF11867 Domain of unknown function (DUF3387) 693 1020 2.6E-116 T 12-10-2018 IPR021810 Protein of unknown function DUF3387 AFE_2790 634f2f6999acf33e5d88d6f92d6e14a2 1022 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 4 203 8.0E-36 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 AFE_2790 634f2f6999acf33e5d88d6f92d6e14a2 1022 Pfam PF04851 Type III restriction enzyme, res subunit 270 440 1.1E-14 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFE_2790 634f2f6999acf33e5d88d6f92d6e14a2 1022 SUPERFAMILY SSF52540 227 479 1.0E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2790 634f2f6999acf33e5d88d6f92d6e14a2 1022 Gene3D G3DSA:3.40.50.300 460 693 2.6E-46 T 12-10-2018 AFE_2790 634f2f6999acf33e5d88d6f92d6e14a2 1022 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 7 693 1.4E-176 T 12-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 AFE_0249 a5013766b841220b7b741b96724b8e8f 236 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 100 219 9.4E-33 T 12-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 AFE_0249 a5013766b841220b7b741b96724b8e8f 236 SUPERFAMILY SSF55729 75 229 4.75E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_0249 a5013766b841220b7b741b96724b8e8f 236 PIRSF PIRSF037208 1 236 1.4E-78 T 12-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 AFE_0249 a5013766b841220b7b741b96724b8e8f 236 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 1 227 35.891 T 12-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 AFE_0249 a5013766b841220b7b741b96724b8e8f 236 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 9 79 1.0E-16 T 12-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 AFE_2581 9c534ce6d2e05b261237cccb1b7f3c57 694 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 7 552 2.5E-186 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2581 9c534ce6d2e05b261237cccb1b7f3c57 694 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 5 692 9.0E-200 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2581 9c534ce6d2e05b261237cccb1b7f3c57 694 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 4 691 23.58 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2581 9c534ce6d2e05b261237cccb1b7f3c57 694 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 8 21 5.5E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2581 9c534ce6d2e05b261237cccb1b7f3c57 694 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 246 261 5.5E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2581 9c534ce6d2e05b261237cccb1b7f3c57 694 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 318 334 5.5E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2581 9c534ce6d2e05b261237cccb1b7f3c57 694 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 51 63 5.5E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2581 9c534ce6d2e05b261237cccb1b7f3c57 694 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 5.5E-31 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 AFE_2581 9c534ce6d2e05b261237cccb1b7f3c57 694 SUPERFAMILY SSF109604 343 492 2.15E-13 T 12-10-2018 AFE_0976 df8ceb62c5a4892d28feeb2639c75e7d 164 Pfam PF02391 MoaE protein 7 119 5.5E-31 T 12-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFE_0976 df8ceb62c5a4892d28feeb2639c75e7d 164 SUPERFAMILY SSF54690 3 140 7.19E-45 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFE_0976 df8ceb62c5a4892d28feeb2639c75e7d 164 Gene3D G3DSA:3.90.1170.40 1 142 3.8E-42 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFE_1772 115fe8a733f11c686d64396afe49e747 203 SUPERFAMILY SSF52540 1 195 2.52E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1772 115fe8a733f11c686d64396afe49e747 203 Gene3D G3DSA:3.40.50.300 4 198 6.1E-35 T 12-10-2018 AFE_1772 115fe8a733f11c686d64396afe49e747 203 PIRSF PIRSF000705 1 202 4.3E-37 T 12-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 AFE_1772 115fe8a733f11c686d64396afe49e747 203 Pfam PF01712 Deoxynucleoside kinase 7 193 1.1E-26 T 12-10-2018 IPR031314 Deoxynucleoside kinase domain AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 ProSitePatterns PS01071 grpE protein signature. 121 163 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 Hamap MF_01151 Protein GrpE [grpE]. 2 165 18.711 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 SUPERFAMILY SSF51064 119 166 1.83E-14 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 Pfam PF01025 GrpE 3 165 5.8E-45 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 SUPERFAMILY SSF58014 17 110 6.41E-23 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 Gene3D G3DSA:2.30.22.10 110 165 9.0E-20 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 Gene3D G3DSA:3.90.20.20 3 108 4.5E-23 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 PRINTS PR00773 GrpE protein signature 118 133 7.4E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 PRINTS PR00773 GrpE protein signature 35 51 7.4E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 PRINTS PR00773 GrpE protein signature 63 78 7.4E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFE_2666 7b2bae0130ed2dfd35c743385d50adc1 171 PRINTS PR00773 GrpE protein signature 144 163 7.4E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFE_0772 be4f2fc5032363d76ca400cb30f154f2 409 Gene3D G3DSA:3.20.20.140 63 357 3.1E-85 T 12-10-2018 AFE_0772 be4f2fc5032363d76ca400cb30f154f2 409 Pfam PF01979 Amidohydrolase family 59 373 1.7E-39 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFE_0772 be4f2fc5032363d76ca400cb30f154f2 409 Gene3D G3DSA:2.30.40.10 17 374 3.1E-85 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_0772 be4f2fc5032363d76ca400cb30f154f2 409 SUPERFAMILY SSF51338 12 75 1.63E-7 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFE_0772 be4f2fc5032363d76ca400cb30f154f2 409 SUPERFAMILY SSF51556 62 355 6.01E-66 T 12-10-2018 IPR032466 Metal-dependent hydrolase AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 SUPERFAMILY SSF88659 201 279 6.35E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 Gene3D G3DSA:1.10.601.10 17 123 8.6E-27 T 12-10-2018 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 PRINTS PR00046 Major sigma-70 factor signature 78 91 1.5E-16 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 PRINTS PR00046 Major sigma-70 factor signature 249 264 1.5E-16 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 PRINTS PR00046 Major sigma-70 factor signature 264 275 1.5E-16 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 PRINTS PR00046 Major sigma-70 factor signature 230 242 1.5E-16 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 Pfam PF04542 Sigma-70 region 2 54 123 9.9E-16 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 279 7.2E-31 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 Pfam PF04545 Sigma-70, region 4 226 277 8.0E-14 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 16 280 2.4E-119 T 12-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 Gene3D G3DSA:1.20.140.160 152 281 5.7E-14 T 12-10-2018 AFE_2750 6faf3afbe21b21d418c50d24953f02de 286 SUPERFAMILY SSF88946 12 123 4.19E-38 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFE_0109 1c5f270407ab8c9dd431e78dbad8d482 360 Gene3D G3DSA:2.40.30.170 58 279 1.1E-67 T 12-10-2018 AFE_0109 1c5f270407ab8c9dd431e78dbad8d482 360 Gene3D G3DSA:1.10.287.470 103 162 1.1E-67 T 12-10-2018 AFE_0109 1c5f270407ab8c9dd431e78dbad8d482 360 Gene3D G3DSA:2.40.420.20 280 352 1.1E-67 T 12-10-2018 AFE_0109 1c5f270407ab8c9dd431e78dbad8d482 360 SUPERFAMILY SSF111369 60 274 1.06E-35 T 12-10-2018 AFE_0109 1c5f270407ab8c9dd431e78dbad8d482 360 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 354 9.6E-75 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 AFE_0109 1c5f270407ab8c9dd431e78dbad8d482 360 Gene3D G3DSA:2.40.50.100 68 196 1.1E-67 T 12-10-2018 AFE_0109 1c5f270407ab8c9dd431e78dbad8d482 360 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 269 7.6E-21 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain AFE_2205 9768835018b804672b921304e327c779 436 Gene3D G3DSA:1.20.1530.10 2 274 2.3E-92 T 12-10-2018 IPR023171 Na/H antiporter domain superfamily AFE_2205 9768835018b804672b921304e327c779 436 Pfam PF06965 Na+/H+ antiporter 1 7 424 4.9E-146 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFE_2205 9768835018b804672b921304e327c779 436 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 5 430 22.731 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFE_2205 9768835018b804672b921304e327c779 436 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 8 424 5.0E-130 T 12-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 AFE_0940 f5c4ce7d382183ad55c86e5f164657bb 368 SUPERFAMILY SSF46548 250 356 4.88E-13 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFE_0940 f5c4ce7d382183ad55c86e5f164657bb 368 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 260 271 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_0940 f5c4ce7d382183ad55c86e5f164657bb 368 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 339 350 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_0940 f5c4ce7d382183ad55c86e5f164657bb 368 Pfam PF17179 4Fe-4S dicluster domain 259 353 7.9E-30 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_2306 fbe64a3cd99fd4e08b033b170009bfc6 255 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 240 2.1E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2306 fbe64a3cd99fd4e08b033b170009bfc6 255 SUPERFAMILY SSF46894 148 241 9.35E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFE_2306 fbe64a3cd99fd4e08b033b170009bfc6 255 SUPERFAMILY SSF52172 23 143 1.1E-5 T 12-10-2018 IPR011006 CheY-like superfamily AFE_2306 fbe64a3cd99fd4e08b033b170009bfc6 255 Gene3D G3DSA:1.10.10.10 141 242 1.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2306 fbe64a3cd99fd4e08b033b170009bfc6 255 SMART SM00862 164 240 1.1E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_0075 99c711e701959e95a67c48dfaa9921a6 119 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 3 105 1.6E-47 T 12-10-2018 IPR026433 EPS-associated transcriptional regulator, MarR family AFE_0075 99c711e701959e95a67c48dfaa9921a6 119 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 2.3E-12 T 12-10-2018 AFE_0075 99c711e701959e95a67c48dfaa9921a6 119 Gene3D G3DSA:1.10.10.10 4 110 6.9E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0075 99c711e701959e95a67c48dfaa9921a6 119 SUPERFAMILY SSF46785 2 102 6.59E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_1415 5d66d006bd1a4bb5095d989ab83cbf9c 88 Gene3D G3DSA:1.20.1260.30 2 87 2.0E-21 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily AFE_1415 5d66d006bd1a4bb5095d989ab83cbf9c 88 Pfam PF12161 HsdM N-terminal domain 8 73 5.3E-17 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain AFE_1415 5d66d006bd1a4bb5095d989ab83cbf9c 88 SUPERFAMILY SSF53335 7 45 1.25E-7 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2690 f1c71dad59eccbb515a8ef06a47dad24 598 Pfam PF02321 Outer membrane efflux protein 383 563 2.6E-19 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_2690 f1c71dad59eccbb515a8ef06a47dad24 598 Pfam PF02321 Outer membrane efflux protein 155 352 2.0E-20 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_2690 f1c71dad59eccbb515a8ef06a47dad24 598 SUPERFAMILY SSF56954 143 564 2.62E-60 T 12-10-2018 AFE_2690 f1c71dad59eccbb515a8ef06a47dad24 598 Gene3D G3DSA:1.20.1600.10 117 567 1.8E-66 T 12-10-2018 AFE_1578 4810e38615dbc81bc5c24ff857d90763 124 Gene3D G3DSA:3.40.50.1010 1 116 3.5E-9 T 12-10-2018 AFE_1578 4810e38615dbc81bc5c24ff857d90763 124 SUPERFAMILY SSF88723 2 118 6.17E-16 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_1578 4810e38615dbc81bc5c24ff857d90763 124 Pfam PF01850 PIN domain 2 108 1.3E-5 T 12-10-2018 IPR002716 PIN domain AFE_0266 eb5011bdb0003e7dea1b39945a945ca1 408 Pfam PF00535 Glycosyl transferase family 2 73 248 2.8E-24 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFE_0266 eb5011bdb0003e7dea1b39945a945ca1 408 SUPERFAMILY SSF53448 58 314 4.13E-38 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0266 eb5011bdb0003e7dea1b39945a945ca1 408 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 31 407 6.9E-174 T 12-10-2018 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB AFE_0266 eb5011bdb0003e7dea1b39945a945ca1 408 Gene3D G3DSA:3.90.550.10 48 308 9.7E-30 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2734 dbdb37c8946a0ab371e06b05b54ee68a 202 Pfam PF01292 Prokaryotic cytochrome b561 17 196 1.1E-11 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFE_2734 dbdb37c8946a0ab371e06b05b54ee68a 202 SUPERFAMILY SSF81342 17 196 3.69E-9 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFE_0689 5ba96c0a26c05f44eb82d6b1759cd899 186 SUPERFAMILY SSF53098 1 100 1.82E-20 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_0689 5ba96c0a26c05f44eb82d6b1759cd899 186 Pfam PF13683 Integrase core domain 22 88 1.1E-11 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFE_2129 cad04e82aad57774b065ab1bcd7a69e5 136 Gene3D G3DSA:3.40.50.1010 1 132 1.8E-40 T 12-10-2018 AFE_2129 cad04e82aad57774b065ab1bcd7a69e5 136 Pfam PF01850 PIN domain 4 124 6.2E-15 T 12-10-2018 IPR002716 PIN domain AFE_2129 cad04e82aad57774b065ab1bcd7a69e5 136 SUPERFAMILY SSF88723 3 131 6.17E-35 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_2129 cad04e82aad57774b065ab1bcd7a69e5 136 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 130 12.596 T 12-10-2018 IPR022907 VapC family GO:0004540 AFE_1501 d0b3207c0ec942e5ca5d8246918f8856 76 Pfam PF09723 Zinc ribbon domain 1 39 2.5E-12 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFE_1501 d0b3207c0ec942e5ca5d8246918f8856 76 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 46 8.8E-15 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFE_1501 d0b3207c0ec942e5ca5d8246918f8856 76 SMART SM00834 1 40 1.8E-13 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFE_1494 ff148da3d68ae5e26a1d7abf6d75815e 344 Pfam PF01497 Periplasmic binding protein 96 284 5.2E-19 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain AFE_1494 ff148da3d68ae5e26a1d7abf6d75815e 344 Gene3D G3DSA:3.40.50.1980 187 290 4.4E-58 T 12-10-2018 AFE_1494 ff148da3d68ae5e26a1d7abf6d75815e 344 Gene3D G3DSA:1.20.58.2180 163 336 4.4E-58 T 12-10-2018 AFE_1494 ff148da3d68ae5e26a1d7abf6d75815e 344 SUPERFAMILY SSF53807 36 311 6.28E-45 T 12-10-2018 AFE_1494 ff148da3d68ae5e26a1d7abf6d75815e 344 Gene3D G3DSA:3.40.50.1980 30 156 2.0E-32 T 12-10-2018 AFE_2148 8b45b3bd4210b92af8a8827200a36f18 181 SMART SM00530 7 62 2.2E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_2148 8b45b3bd4210b92af8a8827200a36f18 181 SUPERFAMILY SSF47413 2 66 3.1E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_2148 8b45b3bd4210b92af8a8827200a36f18 181 Gene3D G3DSA:2.60.120.10 75 179 1.2E-19 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_2148 8b45b3bd4210b92af8a8827200a36f18 181 Gene3D G3DSA:1.10.260.40 1 71 4.4E-19 T 12-10-2018 AFE_2148 8b45b3bd4210b92af8a8827200a36f18 181 Pfam PF07883 Cupin domain 108 178 5.8E-14 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFE_2148 8b45b3bd4210b92af8a8827200a36f18 181 Pfam PF01381 Helix-turn-helix 8 60 6.6E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_2148 8b45b3bd4210b92af8a8827200a36f18 181 SUPERFAMILY SSF51182 55 179 1.01E-22 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_2063 2be01cff9be42a81ca164825bc83de2a 404 Gene3D G3DSA:3.90.1150.10 268 404 1.1E-52 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_2063 2be01cff9be42a81ca164825bc83de2a 404 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 18 399 54.742 T 12-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 AFE_2063 2be01cff9be42a81ca164825bc83de2a 404 PIRSF PIRSF001434 2 402 1.9E-129 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFE_2063 2be01cff9be42a81ca164825bc83de2a 404 SUPERFAMILY SSF53383 37 399 1.46E-121 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_2063 2be01cff9be42a81ca164825bc83de2a 404 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 17 398 3.0E-136 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFE_2063 2be01cff9be42a81ca164825bc83de2a 404 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 17 397 7.6E-175 T 12-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 AFE_2063 2be01cff9be42a81ca164825bc83de2a 404 Gene3D G3DSA:3.40.640.10 12 264 1.0E-86 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_2063 2be01cff9be42a81ca164825bc83de2a 404 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 208 222 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFE_2018 cd4993f64054a38bcc076f688fea6830 274 Gene3D G3DSA:3.30.110.70 162 256 5.4E-12 T 12-10-2018 AFE_2018 cd4993f64054a38bcc076f688fea6830 274 Gene3D G3DSA:3.30.110.70 43 133 3.3E-12 T 12-10-2018 AFE_2018 cd4993f64054a38bcc076f688fea6830 274 Pfam PF01906 Putative heavy-metal-binding 73 129 2.2E-9 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 AFE_2018 cd4993f64054a38bcc076f688fea6830 274 Pfam PF01906 Putative heavy-metal-binding 168 252 2.0E-10 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 AFE_2018 cd4993f64054a38bcc076f688fea6830 274 SUPERFAMILY SSF117782 46 131 4.58E-15 T 12-10-2018 IPR035439 UPF0145 domain superfamily AFE_2018 cd4993f64054a38bcc076f688fea6830 274 SUPERFAMILY SSF117782 165 253 1.14E-13 T 12-10-2018 IPR035439 UPF0145 domain superfamily AFE_0727 8501a0301e683b9836d589e9ec2d667f 299 SUPERFAMILY SSF69593 28 267 3.92E-30 T 12-10-2018 AFE_0727 8501a0301e683b9836d589e9ec2d667f 299 SMART SM00563 90 202 2.6E-32 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFE_0727 8501a0301e683b9836d589e9ec2d667f 299 Pfam PF01553 Acyltransferase 85 198 5.9E-18 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFE_1926 c2547257307bf60157f53853074a17fc 161 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 6 130 1.3E-39 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 AFE_1926 c2547257307bf60157f53853074a17fc 161 Gene3D G3DSA:3.40.50.300 1 146 2.9E-39 T 12-10-2018 AFE_1926 c2547257307bf60157f53853074a17fc 161 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 123 1.6E-35 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 AFE_1926 c2547257307bf60157f53853074a17fc 161 SUPERFAMILY SSF52540 22 137 1.35E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0124 c18410123e1463a05f79f6d90fac6b5c 175 Pfam PF13432 Tetratricopeptide repeat 90 152 1.0E-5 T 12-10-2018 AFE_0124 c18410123e1463a05f79f6d90fac6b5c 175 Pfam PF13432 Tetratricopeptide repeat 32 81 9.1E-6 T 12-10-2018 AFE_0124 c18410123e1463a05f79f6d90fac6b5c 175 Gene3D G3DSA:1.25.40.10 14 171 1.1E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0124 c18410123e1463a05f79f6d90fac6b5c 175 SMART SM00028 85 118 2.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_0124 c18410123e1463a05f79f6d90fac6b5c 175 SMART SM00028 51 84 26.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_0124 c18410123e1463a05f79f6d90fac6b5c 175 SMART SM00028 121 154 7.6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFE_0124 c18410123e1463a05f79f6d90fac6b5c 175 SUPERFAMILY SSF48452 21 154 2.63E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0141 967737c7bbe72babf8c15abcb663e6dc 358 Pfam PF13580 SIS domain 23 146 3.6E-30 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFE_0141 967737c7bbe72babf8c15abcb663e6dc 358 SUPERFAMILY SSF53697 6 189 3.08E-49 T 12-10-2018 AFE_0141 967737c7bbe72babf8c15abcb663e6dc 358 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 224 289 1.7E-11 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFE_0141 967737c7bbe72babf8c15abcb663e6dc 358 Pfam PF01467 Cytidylyltransferase-like 226 317 1.6E-13 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFE_0141 967737c7bbe72babf8c15abcb663e6dc 358 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 2 192 33.926 T 12-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 AFE_0141 967737c7bbe72babf8c15abcb663e6dc 358 Gene3D G3DSA:3.40.50.620 204 357 3.2E-32 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_0141 967737c7bbe72babf8c15abcb663e6dc 358 Gene3D G3DSA:3.40.50.10490 2 197 4.7E-67 T 12-10-2018 AFE_0141 967737c7bbe72babf8c15abcb663e6dc 358 SUPERFAMILY SSF52374 222 352 1.9E-22 T 12-10-2018 AFE_0141 967737c7bbe72babf8c15abcb663e6dc 358 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 218 354 6.3E-58 T 12-10-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 AFE_2257 8ed0339aaeaeb40c563b0fc0eb3234e1 251 Pfam PF09608 Putative transmembrane protein (Alph_Pro_TM) 28 248 1.5E-63 T 12-10-2018 IPR019088 Conserved hypothetical protein CHP02186-related, transmembrane AFE_0748 ed8797417e5b6c5659aa2d56a6d2cd87 220 Pfam PF02666 Phosphatidylserine decarboxylase 46 211 2.0E-31 T 12-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 AFE_0748 ed8797417e5b6c5659aa2d56a6d2cd87 220 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 9 216 35.903 T 12-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 AFE_0748 ed8797417e5b6c5659aa2d56a6d2cd87 220 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 10 214 3.3E-61 T 12-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 AFE_0890 15fea64b16c66ab20e986123d45a524c 93 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 82 8.5E-10 T 12-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AFE_0890 15fea64b16c66ab20e986123d45a524c 93 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 81 1.2E-8 T 12-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AFE_0890 15fea64b16c66ab20e986123d45a524c 93 Gene3D G3DSA:3.30.2310.20 1 93 1.3E-22 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFE_0890 15fea64b16c66ab20e986123d45a524c 93 SUPERFAMILY SSF143011 1 82 2.35E-20 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 SUPERFAMILY SSF50104 121 176 2.15E-19 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 9.6E-67 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 23.893 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 Gene3D G3DSA:2.30.30.30 118 176 3.9E-25 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 7.5E-19 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 7.5E-19 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 7.5E-19 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 Pfam PF00467 KOW motif 127 158 2.3E-6 T 12-10-2018 IPR005824 KOW AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 Pfam PF02357 Transcription termination factor nusG 3 108 1.2E-24 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 Gene3D G3DSA:3.30.70.940 1 117 3.2E-43 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 SMART SM00738 2 111 4.6E-42 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 SUPERFAMILY SSF82679 3 113 2.49E-36 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFE_0314 8e3a915601d7d07cc24a10fcb024a605 177 SMART SM00739 123 150 0.0016 T 12-10-2018 IPR005824 KOW AFE_0365 5a3841803f4f0c3379bc04818363627d 270 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 243 8.7E-89 T 12-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 AFE_0365 5a3841803f4f0c3379bc04818363627d 270 Gene3D G3DSA:3.40.50.1580 3 267 6.2E-86 T 12-10-2018 AFE_0365 5a3841803f4f0c3379bc04818363627d 270 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 263 37.661 T 12-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 AFE_0365 5a3841803f4f0c3379bc04818363627d 270 SUPERFAMILY SSF53167 4 258 1.22E-82 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFE_0365 5a3841803f4f0c3379bc04818363627d 270 Pfam PF01048 Phosphorylase superfamily 5 239 3.5E-43 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFE_0255 725f7f7a09950cc0148777aab1230559 243 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 58 6.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFE_0255 725f7f7a09950cc0148777aab1230559 243 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 66 89 6.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFE_0255 725f7f7a09950cc0148777aab1230559 243 Gene3D G3DSA:1.10.357.10 96 239 1.9E-24 T 12-10-2018 AFE_0255 725f7f7a09950cc0148777aab1230559 243 SUPERFAMILY SSF48498 116 229 1.44E-16 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFE_0255 725f7f7a09950cc0148777aab1230559 243 SUPERFAMILY SSF46689 40 116 3.09E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_0255 725f7f7a09950cc0148777aab1230559 243 Gene3D G3DSA:1.10.10.60 40 91 4.5E-20 T 12-10-2018 AFE_0255 725f7f7a09950cc0148777aab1230559 243 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 91 2.5E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFE_3297 81ebeca520b78fbfda1d4ea64f6cdfea 230 Gene3D G3DSA:3.30.1150.10 103 230 2.9E-10 T 12-10-2018 AFE_3297 81ebeca520b78fbfda1d4ea64f6cdfea 230 Pfam PF13103 TonB C terminal 166 221 1.7E-7 T 12-10-2018 AFE_3297 81ebeca520b78fbfda1d4ea64f6cdfea 230 SUPERFAMILY SSF74653 122 230 4.71E-11 T 12-10-2018 AFE_1818 f42c01bfb4e0e89353bdde079c066b18 274 SUPERFAMILY SSF50685 79 165 6.28E-11 T 12-10-2018 IPR036908 RlpA-like domain superfamily AFE_1818 f42c01bfb4e0e89353bdde079c066b18 274 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 79 169 5.4E-30 T 12-10-2018 IPR012997 Rare lipoprotein A AFE_1818 f42c01bfb4e0e89353bdde079c066b18 274 Gene3D G3DSA:3.30.70.1070 201 273 1.4E-5 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 AFE_1818 f42c01bfb4e0e89353bdde079c066b18 274 Pfam PF05036 Sporulation related domain 201 266 6.0E-8 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 AFE_1818 f42c01bfb4e0e89353bdde079c066b18 274 Gene3D G3DSA:2.40.40.10 77 168 4.5E-30 T 12-10-2018 IPR036908 RlpA-like domain superfamily AFE_1818 f42c01bfb4e0e89353bdde079c066b18 274 SUPERFAMILY SSF110997 198 270 3.27E-11 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 AFE_1818 f42c01bfb4e0e89353bdde079c066b18 274 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 39 168 20.86 T 12-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 AFE_1818 f42c01bfb4e0e89353bdde079c066b18 274 Pfam PF03330 Lytic transglycolase 77 165 1.4E-21 T 12-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain AFE_0703 f6b141ab6a4447ab21a910396c0e5e20 106 SUPERFAMILY SSF57652 29 104 4.71E-5 T 12-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 AFE_1751 0417188a2a7fa90417932439e01081c7 427 SUPERFAMILY SSF56672 1 236 1.07E-70 T 12-10-2018 AFE_1751 0417188a2a7fa90417932439e01081c7 427 Gene3D G3DSA:1.10.150.20 172 231 3.4E-10 T 12-10-2018 AFE_1751 0417188a2a7fa90417932439e01081c7 427 Pfam PF11799 impB/mucB/samB family C-terminal domain 242 355 3.4E-14 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFE_1751 0417188a2a7fa90417932439e01081c7 427 Pfam PF00817 impB/mucB/samB family 6 150 2.4E-34 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 AFE_1751 0417188a2a7fa90417932439e01081c7 427 Gene3D G3DSA:2.30.40.20 11 74 7.7E-43 T 12-10-2018 AFE_1751 0417188a2a7fa90417932439e01081c7 427 Pfam PF13438 Domain of unknown function (DUF4113) 373 423 1.3E-19 T 12-10-2018 IPR025188 Domain of unknown function DUF4113 AFE_1751 0417188a2a7fa90417932439e01081c7 427 Gene3D G3DSA:3.30.70.270 3 155 7.7E-43 T 12-10-2018 AFE_0403 484d3645828cd1e2fe9e12ab10756330 105 SUPERFAMILY SSF51182 20 102 2.25E-16 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_0403 484d3645828cd1e2fe9e12ab10756330 105 Pfam PF06865 Protein of unknown function (DUF1255) 18 102 2.3E-18 T 12-10-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase KEGG: 00230+2.4.2.15|KEGG: 00240+2.4.2.4+2.4.2.3+2.4.2.2|KEGG: 00983+2.4.2.4+2.4.2.3|MetaCyc: PWY-5532|MetaCyc: PWY-7181 AFE_0403 484d3645828cd1e2fe9e12ab10756330 105 Gene3D G3DSA:2.60.120.10 1 105 2.7E-45 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_0977 19ad6bb6e1808939468ae24c3443834a 161 SUPERFAMILY SSF89963 90 161 5.49E-24 T 12-10-2018 IPR036183 YajQ-like superfamily AFE_0977 19ad6bb6e1808939468ae24c3443834a 161 Gene3D G3DSA:3.30.70.860 3 160 2.7E-57 T 12-10-2018 IPR035571 UPF0234-like, C-terminal AFE_0977 19ad6bb6e1808939468ae24c3443834a 161 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 161 27.243 T 12-10-2018 IPR007551 Protein of unknown function DUF520 AFE_0977 19ad6bb6e1808939468ae24c3443834a 161 SUPERFAMILY SSF89963 2 86 9.02E-31 T 12-10-2018 IPR036183 YajQ-like superfamily AFE_0977 19ad6bb6e1808939468ae24c3443834a 161 Pfam PF04461 Protein of unknown function (DUF520) 2 160 7.6E-61 T 12-10-2018 IPR007551 Protein of unknown function DUF520 AFE_0977 19ad6bb6e1808939468ae24c3443834a 161 Gene3D G3DSA:3.30.70.990 9 98 2.7E-57 T 12-10-2018 IPR035570 UPF0234, N-terminal AFE_0760 1715d1ea3e09b54efb4a96e196b51c78 244 Pfam PF01863 Protein of unknown function DUF45 27 232 1.5E-57 T 12-10-2018 IPR002725 Protein of unknown function DUF45 AFE_0760 1715d1ea3e09b54efb4a96e196b51c78 244 Gene3D G3DSA:3.30.2010.10 141 233 1.5E-14 T 12-10-2018 AFE_0278 4f497290e6df5a394f712aeca230af0a 366 SMART SM00155 269 296 2.9E-4 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFE_0278 4f497290e6df5a394f712aeca230af0a 366 SMART SM00155 95 122 12.0 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFE_0278 4f497290e6df5a394f712aeca230af0a 366 SUPERFAMILY SSF56024 156 343 3.14E-37 T 12-10-2018 AFE_0278 4f497290e6df5a394f712aeca230af0a 366 Gene3D G3DSA:3.30.870.10 180 361 7.0E-27 T 12-10-2018 AFE_0278 4f497290e6df5a394f712aeca230af0a 366 SUPERFAMILY SSF56024 8 154 4.4E-25 T 12-10-2018 AFE_0278 4f497290e6df5a394f712aeca230af0a 366 Pfam PF13091 PLD-like domain 196 320 2.7E-26 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFE_0278 4f497290e6df5a394f712aeca230af0a 366 Pfam PF13091 PLD-like domain 14 116 2.2E-7 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFE_0278 4f497290e6df5a394f712aeca230af0a 366 Gene3D G3DSA:3.30.870.10 4 155 1.4E-20 T 12-10-2018 AFE_3168 e5fc331927f1d0a04a8667bca5f3d65e 215 Pfam PF01841 Transglutaminase-like superfamily 30 135 1.2E-15 T 12-10-2018 IPR002931 Transglutaminase-like AFE_3168 e5fc331927f1d0a04a8667bca5f3d65e 215 SUPERFAMILY SSF54001 36 144 5.89E-20 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFE_3168 e5fc331927f1d0a04a8667bca5f3d65e 215 Gene3D G3DSA:3.10.620.30 2 156 2.8E-16 T 12-10-2018 AFE_0178 3f29005a2567c45114af91ae1294686d 257 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 210 221 - T 12-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 AFE_0178 3f29005a2567c45114af91ae1294686d 257 Gene3D G3DSA:3.60.10.10 1 254 1.4E-74 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFE_0178 3f29005a2567c45114af91ae1294686d 257 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 253 2.1E-76 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 AFE_0178 3f29005a2567c45114af91ae1294686d 257 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 253 1.6E-77 T 12-10-2018 AFE_0178 3f29005a2567c45114af91ae1294686d 257 SUPERFAMILY SSF56219 2 254 2.75E-76 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AFE_0178 3f29005a2567c45114af91ae1294686d 257 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 12-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 AFE_0178 3f29005a2567c45114af91ae1294686d 257 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 185 200 - T 12-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 AFE_0178 3f29005a2567c45114af91ae1294686d 257 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 246 3.5E-23 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 Gene3D G3DSA:1.10.10.1100 136 187 2.3E-5 T 12-10-2018 AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 PIRSF PIRSF000375 1 284 3.0E-128 T 12-10-2018 IPR016217 Nitrogen fixation, NifU AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 Gene3D G3DSA:3.90.1010.10 1 135 2.0E-56 T 12-10-2018 AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 Gene3D G3DSA:3.30.300.130 211 285 3.1E-17 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 Pfam PF01106 NifU-like domain 217 280 4.7E-18 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 221 282 1.0E-14 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 SUPERFAMILY SSF82649 2 131 1.02E-44 T 12-10-2018 AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 TIGRFAM TIGR02000 NifU_proper: Fe-S cluster assembly protein NifU 1 283 2.6E-136 T 12-10-2018 IPR010238 NIF system FeS cluster assembly, NifU GO:0005506|GO:0016226|GO:0051536 AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 Pfam PF01592 NifU-like N terminal domain 4 124 2.4E-52 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 Pfam PF04324 BFD-like [2Fe-2S] binding domain 135 184 2.3E-16 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain AFE_1508 97b70f366d23898a12cf7f81dd20fc81 291 SUPERFAMILY SSF117916 207 283 4.14E-19 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFE_1904 7ba13d7c63ce59c7ad776da45dccc01d 61 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.997 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1904 7ba13d7c63ce59c7ad776da45dccc01d 61 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 2.5E-26 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1904 7ba13d7c63ce59c7ad776da45dccc01d 61 Pfam PF01783 Ribosomal L32p protein family 2 57 6.8E-27 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_1904 7ba13d7c63ce59c7ad776da45dccc01d 61 SUPERFAMILY SSF57829 1 55 2.14E-23 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFE_1127 97875d9065753c29e86941806a15c6f5 183 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 7 146 7.7E-25 T 12-10-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase Reactome: R-HSA-74259 AFE_1127 97875d9065753c29e86941806a15c6f5 183 SUPERFAMILY SSF52309 4 157 4.81E-30 T 12-10-2018 AFE_1127 97875d9065753c29e86941806a15c6f5 183 Gene3D G3DSA:3.40.50.450 1 171 2.2E-40 T 12-10-2018 AFE_1206 7e95322f25f1b620452cc2b416cb5643 1142 Gene3D G3DSA:3.40.50.300 418 594 1.7E-6 T 12-10-2018 AFE_1206 7e95322f25f1b620452cc2b416cb5643 1142 SUPERFAMILY SSF52540 409 660 4.32E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1206 7e95322f25f1b620452cc2b416cb5643 1142 Pfam PF03704 Bacterial transcriptional activator domain 101 226 1.9E-9 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFE_1206 7e95322f25f1b620452cc2b416cb5643 1142 Pfam PF13191 AAA ATPase domain 423 595 8.8E-14 T 12-10-2018 AFE_1206 7e95322f25f1b620452cc2b416cb5643 1142 Gene3D G3DSA:1.10.10.10 1 82 4.2E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1206 7e95322f25f1b620452cc2b416cb5643 1142 SUPERFAMILY SSF48452 102 226 1.41E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1206 7e95322f25f1b620452cc2b416cb5643 1142 Gene3D G3DSA:1.25.40.10 83 240 3.9E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1206 7e95322f25f1b620452cc2b416cb5643 1142 SMART SM01043 88 227 5.3E-9 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 Gene3D G3DSA:1.20.1440.90 308 413 6.8E-8 T 12-10-2018 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 194 210 4.6E-61 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 617 646 4.6E-61 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 253 268 4.6E-61 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 575 595 4.6E-61 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 141 154 4.6E-61 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 410 430 4.6E-61 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 753 779 4.6E-61 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 SUPERFAMILY SSF51621 12 929 5.49E-282 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 577 589 - T 12-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 Pfam PF00311 Phosphoenolpyruvate carboxylase 139 929 9.5E-270 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 142 153 - T 12-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_1883 1337d2af9c2e2719a7167f740b7d775d 929 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 3 929 17.146 T 12-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AFE_3004 a2600a7c8caa3b9d250ce36e3fef84f8 132 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 131 7.5E-28 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 AFE_3004 a2600a7c8caa3b9d250ce36e3fef84f8 132 Gene3D G3DSA:3.30.420.270 60 127 4.0E-10 T 12-10-2018 AFE_2632 f0a35470f8819d2ca525c13bd2752821 133 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 5.0E-32 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFE_2632 f0a35470f8819d2ca525c13bd2752821 133 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 5.0E-32 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFE_2632 f0a35470f8819d2ca525c13bd2752821 133 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 5.0E-32 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFE_2632 f0a35470f8819d2ca525c13bd2752821 133 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 5.0E-32 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFE_2632 f0a35470f8819d2ca525c13bd2752821 133 Pfam PF03840 Preprotein translocase SecG subunit 4 73 1.7E-21 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFE_2632 f0a35470f8819d2ca525c13bd2752821 133 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 74 8.6E-27 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFE_1370 303c72785cab1818944bd8d9d6a0db98 484 Pfam PF02397 Bacterial sugar transferase 287 478 2.4E-67 T 12-10-2018 IPR003362 Bacterial sugar transferase AFE_1370 303c72785cab1818944bd8d9d6a0db98 484 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 21 484 2.0E-124 T 12-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase AFE_1370 303c72785cab1818944bd8d9d6a0db98 484 TIGRFAM TIGR03022 WbaP_sugtrans: undecaprenyl-phosphate galactose phosphotransferase WbaP 18 484 4.2E-160 T 12-10-2018 IPR017472 Undecaprenyl-phosphate galactose phosphotransferase, WbaP GO:0000271|GO:0005886|GO:0016021|GO:0016740 AFE_1370 303c72785cab1818944bd8d9d6a0db98 484 Pfam PF13727 CoA-binding domain 82 235 1.3E-5 T 12-10-2018 AFE_0968 8c5ab29e328b3ec7f09719437655d7d0 195 Pfam PF14341 PilX N-terminal 20 70 1.8E-5 T 12-10-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain AFE_1716 ff126a56b1472e292acc11da52629f7e 299 SUPERFAMILY SSF56024 11 150 1.73E-23 T 12-10-2018 AFE_1716 ff126a56b1472e292acc11da52629f7e 299 Gene3D G3DSA:3.30.870.10 4 150 2.3E-25 T 12-10-2018 AFE_1716 ff126a56b1472e292acc11da52629f7e 299 Gene3D G3DSA:3.30.870.10 169 297 1.6E-15 T 12-10-2018 AFE_1716 ff126a56b1472e292acc11da52629f7e 299 SUPERFAMILY SSF56024 199 298 1.39E-10 T 12-10-2018 AFE_1716 ff126a56b1472e292acc11da52629f7e 299 Pfam PF13091 PLD-like domain 13 147 1.2E-19 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFE_1716 ff126a56b1472e292acc11da52629f7e 299 Pfam PF13091 PLD-like domain 200 295 1.1E-12 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFE_2008 eba4d4c77b928451426665e8c0916cbd 166 SUPERFAMILY SSF55961 3 144 3.3E-26 T 12-10-2018 AFE_2008 eba4d4c77b928451426665e8c0916cbd 166 Gene3D G3DSA:3.30.530.20 1 145 5.4E-26 T 12-10-2018 IPR023393 START-like domain superfamily AFE_2008 eba4d4c77b928451426665e8c0916cbd 166 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 144 5.6E-13 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFE_2477 b6486186aa9f2619454e16087d75be36 583 Pfam PF03814 Potassium-transporting ATPase A subunit 10 575 4.8E-208 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_2477 b6486186aa9f2619454e16087d75be36 583 PIRSF PIRSF001294 1 579 6.6E-200 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_2477 b6486186aa9f2619454e16087d75be36 583 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 4 576 2.4E-190 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_2477 b6486186aa9f2619454e16087d75be36 583 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 577 31.38 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 AFE_0731 42f7d18a53061625e9b995d074b1e012 399 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 22 393 38.927 T 12-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 AFE_0731 42f7d18a53061625e9b995d074b1e012 399 Gene3D G3DSA:1.10.3210.10 17 394 6.3E-135 T 12-10-2018 AFE_0731 42f7d18a53061625e9b995d074b1e012 399 Pfam PF01966 HD domain 82 212 9.0E-16 T 12-10-2018 IPR006674 HD domain AFE_0731 42f7d18a53061625e9b995d074b1e012 399 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 45 393 1.1E-92 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 AFE_0731 42f7d18a53061625e9b995d074b1e012 399 SMART SM00471 78 222 2.9E-11 T 12-10-2018 IPR003607 HD/PDEase domain AFE_0731 42f7d18a53061625e9b995d074b1e012 399 Pfam PF13286 Phosphohydrolase-associated domain 300 391 2.7E-29 T 12-10-2018 IPR026875 Phosphohydrolase-associated domain AFE_0731 42f7d18a53061625e9b995d074b1e012 399 SUPERFAMILY SSF109604 36 396 1.55E-88 T 12-10-2018 AFE_1514 a0d769236ea979129208f8a7f1b2aa8b 155 PIRSF PIRSF005788 1 155 5.2E-71 T 12-10-2018 IPR004952 Uncharacterised protein family UPF0460 AFE_1514 a0d769236ea979129208f8a7f1b2aa8b 155 Gene3D G3DSA:1.10.3100.20 1 155 1.0E-75 T 12-10-2018 AFE_1514 a0d769236ea979129208f8a7f1b2aa8b 155 Pfam PF03270 Protein of unknown function, DUF269 34 154 5.5E-56 T 12-10-2018 IPR004952 Uncharacterised protein family UPF0460 AFE_1514 a0d769236ea979129208f8a7f1b2aa8b 155 TIGRFAM TIGR02935 TIGR02935: probable nitrogen fixation protein 14 153 1.9E-68 T 12-10-2018 IPR004952 Uncharacterised protein family UPF0460 AFE_0738 800795a73fde77936029b52494a8a83f 197 Pfam PF05137 Fimbrial assembly protein (PilN) 100 176 1.4E-21 T 12-10-2018 IPR007813 Fimbrial assembly PilN AFE_0488 bc65b3d951475160c057ec40252c322d 381 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 39 148 1.1E-5 T 12-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 AFE_2841 ef9b7f8643933c700f0144962e14becb 315 SUPERFAMILY SSF53067 4 312 1.78E-53 T 12-10-2018 AFE_2841 ef9b7f8643933c700f0144962e14becb 315 Gene3D G3DSA:3.30.420.40 1 141 7.7E-28 T 12-10-2018 AFE_2841 ef9b7f8643933c700f0144962e14becb 315 Pfam PF00480 ROK family 6 310 8.7E-56 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFE_2841 ef9b7f8643933c700f0144962e14becb 315 Gene3D G3DSA:3.30.420.40 142 294 1.6E-40 T 12-10-2018 AFE_3128 0804e8ce826bc63c98a4a543650171a9 168 SUPERFAMILY SSF82784 37 130 1.01E-10 T 12-10-2018 IPR036102 OsmC/Ohr superfamily AFE_3128 0804e8ce826bc63c98a4a543650171a9 168 Gene3D G3DSA:3.30.300.20 10 135 2.2E-7 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta AFE_0250 863a16df40521a3f1a3275561315d28f 259 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 22 245 3.0E-56 T 12-10-2018 IPR005226 UPF0014 family AFE_0250 863a16df40521a3f1a3275561315d28f 259 Pfam PF03649 Uncharacterised protein family (UPF0014) 15 247 3.9E-63 T 12-10-2018 IPR005226 UPF0014 family AFE_2843 74928cbf942356f56894e99bd28d070b 430 Pfam PF04286 Protein of unknown function (DUF445) 49 424 1.7E-98 T 12-10-2018 IPR007383 Protein of unknown function DUF445 AFE_1218 7d53474013cbf653440d7aab412b7fa1 238 Pfam PF14243 Domain of unknown function (DUF4343) 115 210 4.2E-17 T 12-10-2018 IPR025643 Protein of unknown function DUF4343 AFE_0477 74dc5c08bf7108645403abaaee046512 76 SUPERFAMILY SSF89447 4 68 2.27E-12 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFE_0477 74dc5c08bf7108645403abaaee046512 76 Gene3D G3DSA:2.10.260.10 1 76 1.5E-26 T 12-10-2018 AFE_0477 74dc5c08bf7108645403abaaee046512 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 42 8.5E-11 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_0477 74dc5c08bf7108645403abaaee046512 76 SMART SM00966 7 45 5.4E-4 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_2271 edaa09c6dc21c1b4bdaec14b6728ae15 238 SUPERFAMILY SSF46894 138 226 6.52E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFE_2271 edaa09c6dc21c1b4bdaec14b6728ae15 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 2.1E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2271 edaa09c6dc21c1b4bdaec14b6728ae15 238 SMART SM00862 150 225 1.1E-16 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFE_2271 edaa09c6dc21c1b4bdaec14b6728ae15 238 Gene3D G3DSA:1.10.10.10 131 227 2.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2880 9d5ad0425d73b668f9f8de2d44fdccf2 225 Pfam PF00092 von Willebrand factor type A domain 26 175 2.4E-10 T 12-10-2018 IPR002035 von Willebrand factor, type A AFE_2880 9d5ad0425d73b668f9f8de2d44fdccf2 225 PIRSF PIRSF020634 19 222 1.4E-74 T 12-10-2018 IPR011392 Tellurite resistance, TerY AFE_2880 9d5ad0425d73b668f9f8de2d44fdccf2 225 SMART SM00327 21 195 4.1E-9 T 12-10-2018 IPR002035 von Willebrand factor, type A AFE_2880 9d5ad0425d73b668f9f8de2d44fdccf2 225 Gene3D G3DSA:3.40.50.410 22 184 4.0E-18 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_2880 9d5ad0425d73b668f9f8de2d44fdccf2 225 SUPERFAMILY SSF53300 24 174 3.26E-19 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_2857 fbe9f59661043c59afa3318904680af1 237 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 5 223 5.6E-127 T 12-10-2018 IPR014063 Arsenate resistance ArsH AFE_2857 fbe9f59661043c59afa3318904680af1 237 SUPERFAMILY SSF52218 6 224 3.49E-60 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFE_2857 fbe9f59661043c59afa3318904680af1 237 Gene3D G3DSA:3.40.50.360 4 237 1.1E-73 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFE_2857 fbe9f59661043c59afa3318904680af1 237 Pfam PF03358 NADPH-dependent FMN reductase 31 173 2.4E-23 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AFE_2842 c15f051b8f71e4da0ea175654d58a466 269 SUPERFAMILY SSF53681 1 100 1.8E-29 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFE_2842 c15f051b8f71e4da0ea175654d58a466 269 Gene3D G3DSA:3.40.50.1860 3 218 1.8E-61 T 12-10-2018 AFE_2842 c15f051b8f71e4da0ea175654d58a466 269 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 67 75 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFE_2842 c15f051b8f71e4da0ea175654d58a466 269 Hamap MF_00258 Glutamate racemase [murI]. 1 257 28.763 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFE_2842 c15f051b8f71e4da0ea175654d58a466 269 Gene3D G3DSA:3.40.50.1860 92 205 1.8E-61 T 12-10-2018 AFE_2842 c15f051b8f71e4da0ea175654d58a466 269 SUPERFAMILY SSF53681 107 250 6.98E-19 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFE_2842 c15f051b8f71e4da0ea175654d58a466 269 TIGRFAM TIGR00067 glut_race: glutamate racemase 3 215 1.9E-51 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFE_2842 c15f051b8f71e4da0ea175654d58a466 269 Pfam PF01177 Asp/Glu/Hydantoin racemase 3 213 4.7E-22 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 Pfam PF08448 PAS fold 17 107 1.1E-5 T 12-10-2018 IPR013656 PAS fold-4 AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 Pfam PF00512 His Kinase A (phospho-acceptor) domain 138 192 6.7E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 Gene3D G3DSA:3.30.450.20 12 119 3.7E-10 T 12-10-2018 AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 241 354 9.8E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 Gene3D G3DSA:3.30.565.10 199 354 2.9E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 SMART SM00387 240 355 7.5E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 SMART SM00091 11 77 0.0019 T 12-10-2018 IPR000014 PAS domain AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 SUPERFAMILY SSF47384 133 192 1.39E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 SUPERFAMILY SSF55785 15 107 5.48E-7 T 12-10-2018 IPR035965 PAS domain superfamily AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 352 9.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 334 9.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 301 9.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 305 315 9.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 SUPERFAMILY SSF55874 204 352 3.93E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 Gene3D G3DSA:1.10.287.130 139 194 3.4E-12 T 12-10-2018 AFE_2902 da7ec6d3c9ab0ab8afb35df0072cecf7 361 SMART SM00388 136 195 2.5E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_1286 e3c04eb9421758ad6a807ad8842e6b95 304 Pfam PF09588 YqaJ-like viral recombinase domain 8 142 1.4E-23 T 12-10-2018 IPR019080 YqaJ viral recombinase AFE_1286 e3c04eb9421758ad6a807ad8842e6b95 304 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 2 152 1.4E-42 T 12-10-2018 IPR017482 Putative phage-type endonuclease AFE_1286 e3c04eb9421758ad6a807ad8842e6b95 304 Gene3D G3DSA:3.90.320.10 1 198 4.1E-43 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AFE_1286 e3c04eb9421758ad6a807ad8842e6b95 304 SUPERFAMILY SSF52980 2 186 7.51E-41 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 12-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 SUPERFAMILY SSF53098 2 156 8.85E-49 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 Gene3D G3DSA:3.30.420.10 3 157 3.4E-48 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 7.3E-36 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 7.3E-36 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 7.3E-36 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 7.3E-36 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 7.3E-36 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 154 2.2E-54 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 153 45.001 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFE_0060 8f79b50679dd38ddfa51022aca2cd254 166 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 150 5.4E-55 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 AFE_2643 0f430eea4f613a8190792cdbbf8f600d 113 Gene3D G3DSA:3.40.1260.10 3 113 1.1E-14 T 12-10-2018 IPR027396 DsrEFH-like AFE_2643 0f430eea4f613a8190792cdbbf8f600d 113 Pfam PF02635 DsrE/DsrF-like family 6 113 8.3E-13 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFE_2643 0f430eea4f613a8190792cdbbf8f600d 113 SUPERFAMILY SSF75169 1 113 5.15E-14 T 12-10-2018 IPR027396 DsrEFH-like AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 196 214 2.1E-29 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 66 75 2.1E-29 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 227 248 2.1E-29 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 30 41 2.1E-29 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 8 461 9.3E-161 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 SUPERFAMILY SSF52374 9 317 2.95E-95 T 12-10-2018 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 SMART SM00840 346 407 2.7E-25 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 Gene3D G3DSA:3.40.50.620 2 309 7.3E-126 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 21 317 1.8E-126 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 Pfam PF09190 DALR domain 346 407 8.1E-21 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 Gene3D G3DSA:1.20.120.640 310 461 8.6E-45 T 12-10-2018 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 SUPERFAMILY SSF47323 320 461 6.93E-38 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFE_2221 bddd68415f5f18f4e1c740c659789d5b 462 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 7 462 37.785 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AFE_0008 da27773e59f77a7ffb4af818dd031eb9 154 SMART SM00972 86 151 1.6E-22 T 12-10-2018 IPR007893 Spore coat protein U AFE_0008 da27773e59f77a7ffb4af818dd031eb9 154 Pfam PF05229 Spore Coat Protein U domain 16 151 3.2E-31 T 12-10-2018 IPR007893 Spore coat protein U AFE_1881 dadd382ca781929ce760fbec4c4c4754 262 Gene3D G3DSA:1.25.40.10 27 107 5.6E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1881 dadd382ca781929ce760fbec4c4c4754 262 SUPERFAMILY SSF48452 31 91 7.94E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_1881 dadd382ca781929ce760fbec4c4c4754 262 Pfam PF13432 Tetratricopeptide repeat 32 90 1.0E-7 T 12-10-2018 AFE_1448 c60e6d01ba7dd2eebb36915cb3fc9e6d 243 SUPERFAMILY SSF64005 1 223 1.96E-88 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFE_1448 c60e6d01ba7dd2eebb36915cb3fc9e6d 243 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 1 228 1.6E-87 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFE_1448 c60e6d01ba7dd2eebb36915cb3fc9e6d 243 Gene3D G3DSA:3.40.1180.10 1 229 4.6E-95 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFE_1448 c60e6d01ba7dd2eebb36915cb3fc9e6d 243 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 174 191 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 AFE_1448 c60e6d01ba7dd2eebb36915cb3fc9e6d 243 Pfam PF01255 Putative undecaprenyl diphosphate synthase 8 228 4.0E-81 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFE_1448 c60e6d01ba7dd2eebb36915cb3fc9e6d 243 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 1 229 40.74 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFE_2300 4a0f1471d30047f6d73128dc651951e7 124 Pfam PF02472 Biopolymer transport protein ExbD/TolR 5 123 1.0E-23 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 AFE_2300 4a0f1471d30047f6d73128dc651951e7 124 Gene3D G3DSA:3.30.420.270 52 119 1.8E-8 T 12-10-2018 AFE_3267 5d9d8ca6cb9763d585ca1c019f82f012 147 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 145 3.4E-48 T 12-10-2018 IPR003791 Protein of unknown function UPF0178 AFE_3267 5d9d8ca6cb9763d585ca1c019f82f012 147 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 31.648 T 12-10-2018 IPR003791 Protein of unknown function UPF0178 AFE_1865 7d58088a6d7fe363c065347e3cac3705 97 Pfam PF14373 Superinfection immunity protein 35 76 1.3E-16 T 12-10-2018 IPR016410 Bacteriophage-associated immunity protein AFE_1905 d584161ff921c12758b4d3fa7f95cee5 341 SUPERFAMILY SSF53659 1 332 3.87E-105 T 12-10-2018 AFE_1905 d584161ff921c12758b4d3fa7f95cee5 341 Pfam PF02504 Fatty acid synthesis protein 4 318 1.3E-106 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 AFE_1905 d584161ff921c12758b4d3fa7f95cee5 341 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 3 331 1.8E-111 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFE_1905 d584161ff921c12758b4d3fa7f95cee5 341 PIRSF PIRSF002465 1 335 9.8E-128 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFE_1905 d584161ff921c12758b4d3fa7f95cee5 341 Gene3D G3DSA:3.40.718.10 2 340 1.6E-130 T 12-10-2018 AFE_1905 d584161ff921c12758b4d3fa7f95cee5 341 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 337 147.666 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFE_0235 d29297615e209d0ea0c54129133368ae 350 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 74 321 9.0E-54 T 12-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 AFE_0235 d29297615e209d0ea0c54129133368ae 350 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 2 317 4.0E-87 T 12-10-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 AFE_0235 d29297615e209d0ea0c54129133368ae 350 Gene3D G3DSA:3.40.50.2000 178 316 5.5E-35 T 12-10-2018 AFE_0235 d29297615e209d0ea0c54129133368ae 350 Gene3D G3DSA:3.40.50.2000 1 160 3.9E-48 T 12-10-2018 AFE_0235 d29297615e209d0ea0c54129133368ae 350 SUPERFAMILY SSF53756 1 347 2.67E-69 T 12-10-2018 AFE_2947 ac2c99f66f222ac2a12586a79ec592ac 302 Pfam PF13098 Thioredoxin-like domain 140 260 1.7E-12 T 12-10-2018 IPR012336 Thioredoxin-like fold AFE_2947 ac2c99f66f222ac2a12586a79ec592ac 302 Gene3D G3DSA:3.40.30.10 140 274 9.0E-27 T 12-10-2018 AFE_2947 ac2c99f66f222ac2a12586a79ec592ac 302 SUPERFAMILY SSF52833 130 257 1.91E-20 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0540 b27a2afaff0803bc5149b4bf91944eb9 189 Gene3D G3DSA:3.40.50.2020 9 185 1.5E-46 T 12-10-2018 AFE_0540 b27a2afaff0803bc5149b4bf91944eb9 189 SUPERFAMILY SSF53271 29 179 8.52E-26 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFE_0540 b27a2afaff0803bc5149b4bf91944eb9 189 Pfam PF00156 Phosphoribosyl transferase domain 47 168 5.3E-12 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFE_2534 74128a2ff5cd0a763fb15f891bb3c156 388 SUPERFAMILY SSF52768 14 332 7.19E-83 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily AFE_2534 74128a2ff5cd0a763fb15f891bb3c156 388 Gene3D G3DSA:3.40.800.20 11 377 1.3E-98 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFE_2534 74128a2ff5cd0a763fb15f891bb3c156 388 Pfam PF00850 Histone deacetylase domain 35 314 5.5E-59 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFE_2534 74128a2ff5cd0a763fb15f891bb3c156 388 PRINTS PR01270 Histone deacetylase superfamily signature 168 183 7.6E-19 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFE_2534 74128a2ff5cd0a763fb15f891bb3c156 388 PRINTS PR01270 Histone deacetylase superfamily signature 250 260 7.6E-19 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFE_2534 74128a2ff5cd0a763fb15f891bb3c156 388 PRINTS PR01270 Histone deacetylase superfamily signature 136 159 7.6E-19 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFE_1087 f92b356745e9eb93ed87f20c19b13218 396 Gene3D G3DSA:3.30.450.90 2 122 1.1E-21 T 12-10-2018 AFE_1087 f92b356745e9eb93ed87f20c19b13218 396 Pfam PF00437 Type II/IV secretion system protein 28 287 1.7E-59 T 12-10-2018 IPR001482 Type II/IV secretion system protein AFE_1087 f92b356745e9eb93ed87f20c19b13218 396 SUPERFAMILY SSF52540 10 363 3.11E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1087 f92b356745e9eb93ed87f20c19b13218 396 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 217 231 - T 12-10-2018 IPR001482 Type II/IV secretion system protein AFE_1087 f92b356745e9eb93ed87f20c19b13218 396 Gene3D G3DSA:3.40.50.300 124 392 1.1E-85 T 12-10-2018 AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 422 526 2.4E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 SMART SM00388 315 380 3.0E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 Gene3D G3DSA:1.10.287.130 239 375 8.1E-15 T 12-10-2018 AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 Gene3D G3DSA:3.30.565.10 380 528 1.5E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 1.9E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 507 1.9E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 474 1.9E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 488 1.9E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 SUPERFAMILY SSF47384 303 376 3.73E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 Pfam PF00512 His Kinase A (phospho-acceptor) domain 317 376 1.1E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 SMART SM00387 421 528 5.3E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFE_0026 0432b9838f8fb96be4a9d4593b4e41fb 531 SUPERFAMILY SSF55874 371 525 6.68E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_0972 6f53ce95fab922e642f210152944351f 419 Gene3D G3DSA:1.20.81.30 268 379 1.9E-23 T 12-10-2018 AFE_0972 6f53ce95fab922e642f210152944351f 419 Gene3D G3DSA:1.20.81.30 68 183 1.6E-29 T 12-10-2018 AFE_0972 6f53ce95fab922e642f210152944351f 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 396 415 5.9E-17 T 12-10-2018 IPR003004 GspF/PilC family AFE_0972 6f53ce95fab922e642f210152944351f 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 77 89 5.9E-17 T 12-10-2018 IPR003004 GspF/PilC family AFE_0972 6f53ce95fab922e642f210152944351f 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 380 394 5.9E-17 T 12-10-2018 IPR003004 GspF/PilC family AFE_0972 6f53ce95fab922e642f210152944351f 419 PRINTS PR00812 Bacterial general secretion pathway protein F signature 176 204 5.9E-17 T 12-10-2018 IPR003004 GspF/PilC family AFE_0972 6f53ce95fab922e642f210152944351f 419 Pfam PF00482 Type II secretion system (T2SS), protein F 285 407 7.0E-24 T 12-10-2018 IPR018076 Type II secretion system F domain AFE_0972 6f53ce95fab922e642f210152944351f 419 Pfam PF00482 Type II secretion system (T2SS), protein F 82 204 3.8E-31 T 12-10-2018 IPR018076 Type II secretion system F domain AFE_3143 bfef3e8d207a11acb54466b798a69b60 314 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 26 304 1.7E-82 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFE_3143 bfef3e8d207a11acb54466b798a69b60 314 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 78 100 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site AFE_3143 bfef3e8d207a11acb54466b798a69b60 314 Pfam PF01040 UbiA prenyltransferase family 40 288 1.8E-51 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFE_3143 bfef3e8d207a11acb54466b798a69b60 314 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 23 307 17.673 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFE_3143 bfef3e8d207a11acb54466b798a69b60 314 Gene3D G3DSA:1.10.357.140 33 198 3.3E-16 T 12-10-2018 AFE_0635 bfef3e8d207a11acb54466b798a69b60 314 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 26 304 1.7E-82 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFE_0635 bfef3e8d207a11acb54466b798a69b60 314 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 78 100 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site AFE_0635 bfef3e8d207a11acb54466b798a69b60 314 Pfam PF01040 UbiA prenyltransferase family 40 288 1.8E-51 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFE_0635 bfef3e8d207a11acb54466b798a69b60 314 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 23 307 17.673 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFE_0635 bfef3e8d207a11acb54466b798a69b60 314 Gene3D G3DSA:1.10.357.140 33 198 3.3E-16 T 12-10-2018 AFE_1417 1c55f580d4979974cd652d69d5809f58 164 Pfam PF13673 Acetyltransferase (GNAT) domain 29 148 1.5E-8 T 12-10-2018 IPR000182 GNAT domain AFE_1417 1c55f580d4979974cd652d69d5809f58 164 SUPERFAMILY SSF55729 19 152 6.13E-15 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_1417 1c55f580d4979974cd652d69d5809f58 164 Gene3D G3DSA:3.40.630.30 2 161 1.5E-46 T 12-10-2018 AFE_0439 ed3d02231f280957c9d9790a1803ee32 528 Gene3D G3DSA:1.20.1740.10 4 450 1.1E-53 T 12-10-2018 AFE_0439 ed3d02231f280957c9d9790a1803ee32 528 PIRSF PIRSF006060 452 521 98.0 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_0439 ed3d02231f280957c9d9790a1803ee32 528 PIRSF PIRSF006060 1 455 1.0E-58 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_0439 ed3d02231f280957c9d9790a1803ee32 528 Pfam PF13520 Amino acid permease 10 421 1.7E-30 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_2535 85fe19898c2496b1e3b0ad5756407ab1 805 SMART SM00327 609 801 3.0E-5 T 12-10-2018 IPR002035 von Willebrand factor, type A AFE_2535 85fe19898c2496b1e3b0ad5756407ab1 805 Gene3D G3DSA:3.40.50.410 601 780 4.7E-13 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_2535 85fe19898c2496b1e3b0ad5756407ab1 805 SUPERFAMILY SSF53300 610 797 2.47E-15 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_2413 fbfea1502da31d5b0f28757d20fd16d4 220 Pfam PF01695 IstB-like ATP binding protein 12 189 3.4E-53 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 AFE_2413 fbfea1502da31d5b0f28757d20fd16d4 220 SMART SM00382 57 189 0.006 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2413 fbfea1502da31d5b0f28757d20fd16d4 220 PIRSF PIRSF003073 1 208 1.5E-60 T 12-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein AFE_2413 fbfea1502da31d5b0f28757d20fd16d4 220 Gene3D G3DSA:3.40.50.300 21 201 1.7E-40 T 12-10-2018 AFE_2413 fbfea1502da31d5b0f28757d20fd16d4 220 SUPERFAMILY SSF52540 26 182 1.13E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3069 86cbcaa271a9f95c5de39c6007b87f43 326 Gene3D G3DSA:3.40.50.970 1 191 1.5E-75 T 12-10-2018 AFE_3069 86cbcaa271a9f95c5de39c6007b87f43 326 SUPERFAMILY SSF52518 3 203 1.66E-62 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_3069 86cbcaa271a9f95c5de39c6007b87f43 326 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 6.1E-47 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_3069 86cbcaa271a9f95c5de39c6007b87f43 326 SMART SM00861 4 179 1.0E-57 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFE_3069 86cbcaa271a9f95c5de39c6007b87f43 326 Gene3D G3DSA:3.40.50.920 192 325 4.7E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_3069 86cbcaa271a9f95c5de39c6007b87f43 326 SUPERFAMILY SSF52922 188 324 7.33E-38 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFE_3069 86cbcaa271a9f95c5de39c6007b87f43 326 Pfam PF02780 Transketolase, C-terminal domain 195 314 4.5E-34 T 12-10-2018 IPR033248 Transketolase, C-terminal domain AFE_0327 058ff66bc41a9217cb9c926455ef8291 210 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 205 3.6E-86 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0327 058ff66bc41a9217cb9c926455ef8291 210 SUPERFAMILY SSF50447 1 209 3.0E-76 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFE_0327 058ff66bc41a9217cb9c926455ef8291 210 Pfam PF00297 Ribosomal protein L3 100 183 9.7E-15 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0327 058ff66bc41a9217cb9c926455ef8291 210 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 208 38.382 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0327 058ff66bc41a9217cb9c926455ef8291 210 Gene3D G3DSA:2.40.50.620 33 94 1.3E-14 T 12-10-2018 AFE_0327 058ff66bc41a9217cb9c926455ef8291 210 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site AFE_0327 058ff66bc41a9217cb9c926455ef8291 210 Gene3D G3DSA:2.40.30.10 130 210 1.4E-13 T 12-10-2018 AFE_1321 86b18ac97914950399f8ad9df10e3412 111 SUPERFAMILY SSF117782 1 109 2.62E-26 T 12-10-2018 IPR035439 UPF0145 domain superfamily AFE_1321 86b18ac97914950399f8ad9df10e3412 111 Gene3D G3DSA:3.30.110.70 3 111 2.7E-25 T 12-10-2018 AFE_1321 86b18ac97914950399f8ad9df10e3412 111 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 107 19.296 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 AFE_1321 86b18ac97914950399f8ad9df10e3412 111 Pfam PF01906 Putative heavy-metal-binding 1 107 1.8E-26 T 12-10-2018 IPR002765 Uncharacterised protein family UPF0145 AFE_0039 fc708518106a00ab19a053059c13bbea 484 Pfam PF02321 Outer membrane efflux protein 73 260 2.4E-13 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_0039 fc708518106a00ab19a053059c13bbea 484 Pfam PF02321 Outer membrane efflux protein 296 474 1.3E-17 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 AFE_0039 fc708518106a00ab19a053059c13bbea 484 Gene3D G3DSA:1.20.1600.10 63 477 7.6E-73 T 12-10-2018 AFE_0039 fc708518106a00ab19a053059c13bbea 484 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 476 2.0E-64 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 AFE_0039 fc708518106a00ab19a053059c13bbea 484 Gene3D G3DSA:2.20.200.10 111 365 7.6E-73 T 12-10-2018 AFE_0039 fc708518106a00ab19a053059c13bbea 484 SUPERFAMILY SSF56954 5 478 1.11E-68 T 12-10-2018 AFE_2935 ae25cc6ca9682400a2470af3eef5dea4 801 Pfam PF00593 TonB dependent receptor 294 799 8.1E-32 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel AFE_2935 ae25cc6ca9682400a2470af3eef5dea4 801 Gene3D G3DSA:2.40.170.20 200 801 1.2E-52 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily AFE_2935 ae25cc6ca9682400a2470af3eef5dea4 801 SUPERFAMILY SSF56935 60 801 5.13E-68 T 12-10-2018 AFE_2935 ae25cc6ca9682400a2470af3eef5dea4 801 Gene3D G3DSA:2.170.130.10 62 191 3.4E-7 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily AFE_2935 ae25cc6ca9682400a2470af3eef5dea4 801 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 784 801 - T 12-10-2018 IPR010917 TonB-dependent receptor, conserved site AFE_2187 dfbad3033350dd4885b5eb89d7641d90 662 Pfam PF00580 UvrD/REP helicase N-terminal domain 7 266 1.5E-67 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFE_2187 dfbad3033350dd4885b5eb89d7641d90 662 Pfam PF13361 UvrD-like helicase C-terminal domain 272 609 4.3E-68 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFE_2187 dfbad3033350dd4885b5eb89d7641d90 662 SUPERFAMILY SSF52540 4 635 8.82E-160 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2187 dfbad3033350dd4885b5eb89d7641d90 662 Gene3D G3DSA:1.10.10.160 112 182 6.2E-89 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily AFE_2187 dfbad3033350dd4885b5eb89d7641d90 662 Gene3D G3DSA:3.40.50.300 8 267 6.2E-89 T 12-10-2018 AFE_2187 dfbad3033350dd4885b5eb89d7641d90 662 Gene3D G3DSA:3.40.50.300 275 628 1.9E-116 T 12-10-2018 AFE_2187 dfbad3033350dd4885b5eb89d7641d90 662 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 5 660 36.643 T 12-10-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 AFE_2187 dfbad3033350dd4885b5eb89d7641d90 662 Gene3D G3DSA:1.10.486.10 378 540 1.9E-116 T 12-10-2018 AFE_2219 9c4f98595ec7a9ac1e2e625161e26927 317 SUPERFAMILY SSF55174 17 68 5.72E-9 T 12-10-2018 AFE_2219 9c4f98595ec7a9ac1e2e625161e26927 317 SMART SM00363 18 85 6.4E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_2219 9c4f98595ec7a9ac1e2e625161e26927 317 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 137 151 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2219 9c4f98595ec7a9ac1e2e625161e26927 317 Pfam PF01479 S4 domain 18 64 9.9E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_2219 9c4f98595ec7a9ac1e2e625161e26927 317 Gene3D G3DSA:3.30.2350.10 90 315 5.7E-74 T 12-10-2018 AFE_2219 9c4f98595ec7a9ac1e2e625161e26927 317 SUPERFAMILY SSF55120 89 312 4.16E-61 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2219 9c4f98595ec7a9ac1e2e625161e26927 317 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 15 311 2.2E-76 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2219 9c4f98595ec7a9ac1e2e625161e26927 317 Pfam PF00849 RNA pseudouridylate synthase 98 248 1.3E-26 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_2219 9c4f98595ec7a9ac1e2e625161e26927 317 Gene3D G3DSA:3.10.290.10 6 69 1.2E-15 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFE_2542 3ff0fec1b598cbf2467f0727d81619b9 447 SUPERFAMILY SSF56935 27 447 6.41E-46 T 12-10-2018 AFE_2542 3ff0fec1b598cbf2467f0727d81619b9 447 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 20 447 1.3E-32 T 12-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) AFE_2542 3ff0fec1b598cbf2467f0727d81619b9 447 Gene3D G3DSA:2.40.160.60 26 447 3.0E-78 T 12-10-2018 AFE_0973 dcb97fae435e670c21247bfac1623dd9 334 Pfam PF01343 Peptidase family S49 154 299 2.2E-40 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 AFE_0973 dcb97fae435e670c21247bfac1623dd9 334 Gene3D G3DSA:3.90.226.10 99 293 1.6E-39 T 12-10-2018 AFE_0973 dcb97fae435e670c21247bfac1623dd9 334 Gene3D G3DSA:3.40.1750.20 194 258 1.6E-39 T 12-10-2018 AFE_0973 dcb97fae435e670c21247bfac1623dd9 334 SUPERFAMILY SSF52096 94 291 3.83E-27 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFE_0973 dcb97fae435e670c21247bfac1623dd9 334 Pfam PF08496 Peptidase family S49 N-terminal 4 150 6.4E-45 T 12-10-2018 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 AFE_0413 d57d98cabf96b44e8e3547f60773b165 125 Gene3D G3DSA:3.40.50.1010 1 118 2.1E-10 T 12-10-2018 AFE_0413 d57d98cabf96b44e8e3547f60773b165 125 Pfam PF01850 PIN domain 1 113 7.7E-10 T 12-10-2018 IPR002716 PIN domain AFE_0413 d57d98cabf96b44e8e3547f60773b165 125 SUPERFAMILY SSF88723 1 117 1.21E-18 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_0085 1221fe64a84c4e2933a49f8e9de37489 73 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 51 6.6E-8 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM AFE_0085 1221fe64a84c4e2933a49f8e9de37489 73 SUPERFAMILY SSF143120 1 41 1.96E-6 T 12-10-2018 IPR036165 YefM-like superfamily AFE_0883 6a8f1977da1975a8c13332ed2c35a507 39 SUPERFAMILY SSF51735 1 32 2.25E-11 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0883 6a8f1977da1975a8c13332ed2c35a507 39 Gene3D G3DSA:3.40.50.720 1 37 4.6E-11 T 12-10-2018 AFE_1511 05296ff859afd98ac15ced9fb4b77f6a 217 Pfam PF04891 NifQ 28 203 2.2E-51 T 12-10-2018 IPR006975 NifQ GO:0009399|GO:0030151 AFE_2659 8da55a36a7382b3f2d5d892893348e08 468 Gene3D G3DSA:1.20.1740.10 15 463 3.2E-38 T 12-10-2018 AFE_2659 8da55a36a7382b3f2d5d892893348e08 468 Pfam PF13520 Amino acid permease 40 443 2.0E-27 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_2659 8da55a36a7382b3f2d5d892893348e08 468 PIRSF PIRSF006060 15 466 1.1E-53 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_2868 a86e02362e8bdaf96748a898b32d6850 153 Gene3D G3DSA:1.20.120.520 4 147 1.3E-11 T 12-10-2018 AFE_2868 a86e02362e8bdaf96748a898b32d6850 153 Pfam PF01814 Hemerythrin HHE cation binding domain 4 128 2.0E-14 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 AFE_0280 3104c6d234f8d647e8080ce88e856b19 161 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 133 1.2E-28 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 AFE_0280 3104c6d234f8d647e8080ce88e856b19 161 Gene3D G3DSA:3.30.530.20 1 143 1.2E-38 T 12-10-2018 IPR023393 START-like domain superfamily AFE_0280 3104c6d234f8d647e8080ce88e856b19 161 SUPERFAMILY SSF55961 1 143 2.2E-31 T 12-10-2018 AFE_0067 59c6b0126771abf90cae0c59de30167e 422 Gene3D G3DSA:3.40.50.10070 21 161 9.9E-35 T 12-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 AFE_0067 59c6b0126771abf90cae0c59de30167e 422 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 16 421 2.6E-151 T 12-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 AFE_0067 59c6b0126771abf90cae0c59de30167e 422 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 9 420 42.465 T 12-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 AFE_0067 59c6b0126771abf90cae0c59de30167e 422 Gene3D G3DSA:2.120.10.30 162 422 1.4E-81 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFE_0067 59c6b0126771abf90cae0c59de30167e 422 Pfam PF04052 TolB amino-terminal domain 25 126 1.4E-23 T 12-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 AFE_0067 59c6b0126771abf90cae0c59de30167e 422 SUPERFAMILY SSF69304 153 421 3.27E-53 T 12-10-2018 AFE_0067 59c6b0126771abf90cae0c59de30167e 422 Pfam PF07676 WD40-like Beta Propeller Repeat 197 222 0.0069 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFE_0067 59c6b0126771abf90cae0c59de30167e 422 Pfam PF07676 WD40-like Beta Propeller Repeat 237 266 0.034 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFE_0067 59c6b0126771abf90cae0c59de30167e 422 Pfam PF07676 WD40-like Beta Propeller Repeat 275 309 1.5E-13 T 12-10-2018 IPR011659 WD40-like Beta Propeller AFE_0067 59c6b0126771abf90cae0c59de30167e 422 SUPERFAMILY SSF52964 30 158 3.4E-30 T 12-10-2018 AFE_0854 8e4365139957a79ed90ec210a5a2e50f 196 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 184 3.0E-49 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFE_0854 8e4365139957a79ed90ec210a5a2e50f 196 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 71 7.3E-15 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFE_0854 8e4365139957a79ed90ec210a5a2e50f 196 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFE_0854 8e4365139957a79ed90ec210a5a2e50f 196 PIRSF PIRSF000847 1 192 2.4E-46 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFE_0854 8e4365139957a79ed90ec210a5a2e50f 196 Gene3D G3DSA:1.20.120.1760 2 179 9.3E-13 T 12-10-2018 AFE_1579 22740c79c9b7373f716f9eca0d1ba901 65 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 46 6.7E-13 T 12-10-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB AFE_1979 57f30d45d6e3d0ac5a55a6a5ecfc4ee6 123 SUPERFAMILY SSF52833 2 103 2.65E-33 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1979 57f30d45d6e3d0ac5a55a6a5ecfc4ee6 123 PIRSF PIRSF000077 1 104 4.9E-29 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFE_1979 57f30d45d6e3d0ac5a55a6a5ecfc4ee6 123 Pfam PF00085 Thioredoxin 3 102 5.3E-28 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFE_1979 57f30d45d6e3d0ac5a55a6a5ecfc4ee6 123 Gene3D G3DSA:3.40.30.10 1 117 1.7E-32 T 12-10-2018 AFE_1979 57f30d45d6e3d0ac5a55a6a5ecfc4ee6 123 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 5.4E-31 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFE_1979 57f30d45d6e3d0ac5a55a6a5ecfc4ee6 123 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFE_1979 57f30d45d6e3d0ac5a55a6a5ecfc4ee6 123 PRINTS PR00421 Thioredoxin family signature 29 38 3.9E-8 T 12-10-2018 AFE_1979 57f30d45d6e3d0ac5a55a6a5ecfc4ee6 123 PRINTS PR00421 Thioredoxin family signature 21 29 3.9E-8 T 12-10-2018 AFE_1979 57f30d45d6e3d0ac5a55a6a5ecfc4ee6 123 PRINTS PR00421 Thioredoxin family signature 68 79 3.9E-8 T 12-10-2018 AFE_3295 af4ce743105f3d13c04469463c1f7dba 294 Pfam PF00483 Nucleotidyl transferase 4 239 8.1E-64 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFE_3295 af4ce743105f3d13c04469463c1f7dba 294 Gene3D G3DSA:3.90.550.10 1 293 1.3E-79 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_3295 af4ce743105f3d13c04469463c1f7dba 294 SUPERFAMILY SSF53448 1 288 1.51E-86 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_3295 af4ce743105f3d13c04469463c1f7dba 294 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 4 288 1.3E-143 T 12-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 AFE_2174 336beff718c1c7bf1c045673857d7db3 147 Gene3D G3DSA:3.90.79.10 1 147 3.8E-35 T 12-10-2018 AFE_2174 336beff718c1c7bf1c045673857d7db3 147 Pfam PF00293 NUDIX domain 6 116 2.0E-11 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFE_2174 336beff718c1c7bf1c045673857d7db3 147 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFE_2174 336beff718c1c7bf1c045673857d7db3 147 SUPERFAMILY SSF55811 3 139 2.84E-23 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFE_0472 65fe2925b77505fd1eedf31e5b09d25e 393 Gene3D G3DSA:3.90.1150.10 289 386 1.2E-129 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0472 65fe2925b77505fd1eedf31e5b09d25e 393 Gene3D G3DSA:3.40.640.10 64 288 1.2E-129 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_0472 65fe2925b77505fd1eedf31e5b09d25e 393 SUPERFAMILY SSF53383 2 390 5.44E-110 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_0472 65fe2925b77505fd1eedf31e5b09d25e 393 Pfam PF00155 Aminotransferase class I and II 32 371 1.2E-56 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFE_1753 cf2408b08d46e99c393d7a277601f0fe 644 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 10 628 32.35 T 12-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup AFE_1753 cf2408b08d46e99c393d7a277601f0fe 644 Pfam PF02705 K+ potassium transporter 19 550 6.5E-205 T 12-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 AFE_0041 a88c20f4c6efeebb8c89e5cf4d7ace71 385 Pfam PF03595 Voltage-dependent anion channel 7 341 2.6E-78 T 12-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 AFE_0041 a88c20f4c6efeebb8c89e5cf4d7ace71 385 Gene3D G3DSA:1.50.10.150 3 352 7.5E-21 T 12-10-2018 IPR038665 Voltage-dependent anion channel superfamily AFE_2259 64c66f8625f69cea125b407cba7d06d8 177 Gene3D G3DSA:3.40.50.620 4 155 1.4E-14 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2259 64c66f8625f69cea125b407cba7d06d8 177 Pfam PF00582 Universal stress protein family 5 155 7.2E-9 T 12-10-2018 IPR006016 UspA AFE_2259 64c66f8625f69cea125b407cba7d06d8 177 SUPERFAMILY SSF52402 6 159 7.37E-14 T 12-10-2018 AFE_2578 da89673f92051549a86750275a94d9d0 120 Gene3D G3DSA:3.30.450.30 2 120 5.6E-30 T 12-10-2018 AFE_2578 da89673f92051549a86750275a94d9d0 120 SUPERFAMILY SSF103196 4 120 2.44E-29 T 12-10-2018 AFE_2578 da89673f92051549a86750275a94d9d0 120 Pfam PF03259 Roadblock/LC7 domain 15 96 1.5E-16 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFE_2578 da89673f92051549a86750275a94d9d0 120 SMART SM00960 6 96 9.8E-24 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain AFE_2656 b77575024d586bbe2eef3777d171f87f 245 Pfam PF01904 Protein of unknown function DUF72 26 240 3.7E-63 T 12-10-2018 IPR002763 Protein of unknown function DUF72 AFE_2656 b77575024d586bbe2eef3777d171f87f 245 Gene3D G3DSA:3.20.20.410 3 244 2.0E-74 T 12-10-2018 IPR036520 UPF0759 superfamily AFE_2656 b77575024d586bbe2eef3777d171f87f 245 SUPERFAMILY SSF117396 9 244 7.32E-81 T 12-10-2018 IPR036520 UPF0759 superfamily AFE_2047 fbb870dd55a04e8e57440a0ea5c278cc 103 SUPERFAMILY SSF52943 16 100 1.07E-10 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_2047 fbb870dd55a04e8e57440a0ea5c278cc 103 Pfam PF00231 ATP synthase 28 100 4.8E-10 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_2047 fbb870dd55a04e8e57440a0ea5c278cc 103 Gene3D G3DSA:1.10.287.80 24 94 3.2E-7 T 12-10-2018 AFE_2658 79100b0eb0480c1c9478220bb16aef40 100 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 31 91 2.3E-19 T 12-10-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system AFE_0982 abb1f0e08261fc53082895c7c2ece7ea 508 Pfam PF02347 Glycine cleavage system P-protein 47 313 7.0E-10 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AFE_0982 abb1f0e08261fc53082895c7c2ece7ea 508 Gene3D G3DSA:3.40.640.10 99 326 6.9E-55 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_0982 abb1f0e08261fc53082895c7c2ece7ea 508 Gene3D G3DSA:3.90.1150.10 356 489 2.4E-42 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0982 abb1f0e08261fc53082895c7c2ece7ea 508 SUPERFAMILY SSF53383 45 498 5.89E-102 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 6.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 6.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 6.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.7E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.7E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.7E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.7E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.7E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 1.7E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 Gene3D G3DSA:3.40.50.720 2 240 2.8E-76 T 12-10-2018 AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 187 1.8E-5 T 12-10-2018 AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 SUPERFAMILY SSF51735 3 238 5.44E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_0793 96a5afeeee0fd60fd1ef0b2debfe70de 240 Pfam PF00106 short chain dehydrogenase 3 192 1.4E-56 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3113 f8e8957e45ad75c62b0b5dfff838ce38 352 Pfam PF01578 Cytochrome C assembly protein 138 347 3.2E-48 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFE_3113 f8e8957e45ad75c62b0b5dfff838ce38 352 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 106 350 9.3E-79 T 12-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 AFE_1208 94850cd5e1ac8f331d3dc07fe87496e7 991 SMART SM00869 720 981 1.2E-11 T 12-10-2018 IPR005546 Autotransporter beta-domain AFE_1208 94850cd5e1ac8f331d3dc07fe87496e7 991 Gene3D G3DSA:2.40.128.130 685 990 3.3E-25 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily AFE_1208 94850cd5e1ac8f331d3dc07fe87496e7 991 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 24 5.2E-10 T 12-10-2018 IPR024973 ESPR domain AFE_1208 94850cd5e1ac8f331d3dc07fe87496e7 991 Pfam PF03797 Autotransporter beta-domain 724 970 1.8E-24 T 12-10-2018 IPR005546 Autotransporter beta-domain AFE_1208 94850cd5e1ac8f331d3dc07fe87496e7 991 SUPERFAMILY SSF103515 716 991 6.8E-27 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily AFE_2577 dd8d75ea4356d74e8f8af69311d2b26a 212 Gene3D G3DSA:3.30.450.30 90 169 4.7E-5 T 12-10-2018 AFE_2577 dd8d75ea4356d74e8f8af69311d2b26a 212 SUPERFAMILY SSF103196 91 152 2.33E-8 T 12-10-2018 AFE_2026 82dfd997ac8f890744614486ba7acba7 97 Pfam PF12840 Helix-turn-helix domain 16 72 4.8E-10 T 12-10-2018 AFE_2026 82dfd997ac8f890744614486ba7acba7 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 1.0E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2026 82dfd997ac8f890744614486ba7acba7 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 1.0E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2026 82dfd997ac8f890744614486ba7acba7 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.0E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2026 82dfd997ac8f890744614486ba7acba7 97 SUPERFAMILY SSF46785 5 91 5.89E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2026 82dfd997ac8f890744614486ba7acba7 97 SMART SM00418 16 94 8.0E-16 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFE_2026 82dfd997ac8f890744614486ba7acba7 97 Gene3D G3DSA:1.10.10.10 1 96 1.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1854 dabd9d7a77cb1ac5ebc2775e14003a8a 418 SUPERFAMILY SSF51905 2 207 1.4E-31 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1854 dabd9d7a77cb1ac5ebc2775e14003a8a 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 318 2.3E-39 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFE_1854 dabd9d7a77cb1ac5ebc2775e14003a8a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 5.7E-6 T 12-10-2018 AFE_1854 dabd9d7a77cb1ac5ebc2775e14003a8a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 299 5.7E-6 T 12-10-2018 AFE_1854 dabd9d7a77cb1ac5ebc2775e14003a8a 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 5.7E-6 T 12-10-2018 AFE_1854 dabd9d7a77cb1ac5ebc2775e14003a8a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.7E-5 T 12-10-2018 AFE_1854 dabd9d7a77cb1ac5ebc2775e14003a8a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 1.7E-5 T 12-10-2018 AFE_1854 dabd9d7a77cb1ac5ebc2775e14003a8a 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 292 299 1.7E-5 T 12-10-2018 AFE_1854 dabd9d7a77cb1ac5ebc2775e14003a8a 418 Gene3D G3DSA:3.50.50.100 1 389 2.0E-101 T 12-10-2018 AFE_1854 dabd9d7a77cb1ac5ebc2775e14003a8a 418 SUPERFAMILY SSF51905 3 370 3.02E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_2343 aba5421b97c9cbb45aed2652cc4970eb 242 Gene3D G3DSA:3.30.230.70 11 239 2.1E-64 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_2343 aba5421b97c9cbb45aed2652cc4970eb 242 SUPERFAMILY SSF55666 153 235 1.83E-25 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_2343 aba5421b97c9cbb45aed2652cc4970eb 242 ProSitePatterns PS01277 Ribonuclease PH signature. 117 129 - T 12-10-2018 IPR018336 Ribonuclease PH, conserved site AFE_2343 aba5421b97c9cbb45aed2652cc4970eb 242 Hamap MF_00564 Ribonuclease PH [rph]. 12 238 45.013 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 AFE_2343 aba5421b97c9cbb45aed2652cc4970eb 242 Pfam PF03725 3' exoribonuclease family, domain 2 160 225 6.5E-12 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_2343 aba5421b97c9cbb45aed2652cc4970eb 242 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 235 5.3E-117 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 AFE_2343 aba5421b97c9cbb45aed2652cc4970eb 242 SUPERFAMILY SSF54211 2 182 8.6E-46 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFE_2343 aba5421b97c9cbb45aed2652cc4970eb 242 Pfam PF01138 3' exoribonuclease family, domain 1 12 141 7.7E-23 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFE_0048 28dd689f59f571be22900025d47bc11a 360 Pfam PF07680 TQO small subunit DoxA 239 355 2.1E-17 T 12-10-2018 IPR011636 Thiosulphate:quinone oxidoreductase small subunit DoxA KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 AFE_0048 28dd689f59f571be22900025d47bc11a 360 PIRSF PIRSF037390 8 360 2.5E-117 T 12-10-2018 IPR017192 Thiosulphate:quinone oxidoreductase, fused subunit DoxA/ DoxD AFE_0048 28dd689f59f571be22900025d47bc11a 360 Pfam PF04173 TQO small subunit DoxD 26 179 8.0E-24 T 12-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 AFE_0272 8da73261257aca191bdfd86017df5ea5 165 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 6 157 2.5E-60 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFE_0272 8da73261257aca191bdfd86017df5ea5 165 SUPERFAMILY SSF52255 5 159 3.01E-61 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFE_0272 8da73261257aca191bdfd86017df5ea5 165 PIRSF PIRSF001338 1 161 3.9E-61 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 AFE_0272 8da73261257aca191bdfd86017df5ea5 165 Pfam PF00731 AIR carboxylase 6 152 2.9E-59 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFE_0272 8da73261257aca191bdfd86017df5ea5 165 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 6 159 30.815 T 12-10-2018 IPR033747 Class I PurE AFE_0272 8da73261257aca191bdfd86017df5ea5 165 Gene3D G3DSA:3.40.50.7700 1 164 3.1E-67 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFE_0272 8da73261257aca191bdfd86017df5ea5 165 SMART SM01001 4 155 2.8E-89 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFE_0467 7a62faf04610f6e04eecbf6b2ce2cf8c 170 Pfam PF13511 Domain of unknown function (DUF4124) 10 59 1.9E-13 T 12-10-2018 IPR025392 Domain of unknown function DUF4124 AFE_1827 a2bb2f2c5842d690c5ff9a7dca4ce147 408 Pfam PF13406 Transglycosylase SLT domain 101 400 1.4E-75 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 AFE_1827 a2bb2f2c5842d690c5ff9a7dca4ce147 408 SUPERFAMILY SSF53955 108 403 6.19E-66 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFE_1827 a2bb2f2c5842d690c5ff9a7dca4ce147 408 Gene3D G3DSA:1.10.8.350 106 275 6.3E-69 T 12-10-2018 AFE_1827 a2bb2f2c5842d690c5ff9a7dca4ce147 408 Gene3D G3DSA:1.10.530.10 143 402 6.3E-69 T 12-10-2018 AFE_0895 02a9d361e6baa140916897c176c37405 362 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 361 1.1E-156 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFE_0895 02a9d361e6baa140916897c176c37405 362 Gene3D G3DSA:3.40.640.10 18 257 1.0E-90 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_0895 02a9d361e6baa140916897c176c37405 362 SUPERFAMILY SSF53383 5 359 3.24E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_0895 02a9d361e6baa140916897c176c37405 362 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 3 361 50.9 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFE_0895 02a9d361e6baa140916897c176c37405 362 Gene3D G3DSA:3.90.1150.10 258 362 3.4E-40 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0895 02a9d361e6baa140916897c176c37405 362 PIRSF PIRSF000525 1 362 1.8E-150 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFE_0895 02a9d361e6baa140916897c176c37405 362 Pfam PF00266 Aminotransferase class-V 5 350 1.0E-58 T 12-10-2018 IPR000192 Aminotransferase class V domain AFE_0895 02a9d361e6baa140916897c176c37405 362 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 188 207 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AFE_2200 6cb5a82d68fc1ef611ec30b18ccf648d 373 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 355 1.4E-56 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 AFE_2200 6cb5a82d68fc1ef611ec30b18ccf648d 373 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 6 355 1.4E-76 T 12-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 AFE_0525 0943585fc294f62318b732f07dd645c0 472 Gene3D G3DSA:2.70.70.10 344 471 9.8E-29 T 12-10-2018 IPR011055 Duplicated hybrid motif AFE_0525 0943585fc294f62318b732f07dd645c0 472 Pfam PF01551 Peptidase family M23 373 466 2.7E-22 T 12-10-2018 IPR016047 Peptidase M23 AFE_0525 0943585fc294f62318b732f07dd645c0 472 SUPERFAMILY SSF51261 293 470 9.42E-34 T 12-10-2018 IPR011055 Duplicated hybrid motif AFE_0525 0943585fc294f62318b732f07dd645c0 472 Gene3D G3DSA:1.20.5.340 17 121 3.2E-6 T 12-10-2018 AFE_2675 448d10d9b482f613d31c31eadf1bb9e7 162 Pfam PF08897 Domain of unknown function (DUF1841) 21 153 1.7E-47 T 12-10-2018 IPR014993 Protein of unknown function DUF1841 AFE_3013 ca9e5543cea24affb251444aa156ec66 436 Pfam PF05159 Capsule polysaccharide biosynthesis protein 72 379 2.4E-76 T 12-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 AFE_1497 d51c3451dfa299c94764f825f71c5958 442 Gene3D G3DSA:2.40.160.10 17 350 5.2E-16 T 12-10-2018 IPR023614 Porin domain superfamily AFE_1497 d51c3451dfa299c94764f825f71c5958 442 Pfam PF03573 outer membrane porin, OprD family 127 252 1.6E-7 T 12-10-2018 IPR005318 Outer membrane porin, bacterial GO:0016021 AFE_2621 9f9ad122f026653fb7fdb825ec420d14 198 Gene3D G3DSA:1.20.120.1200 5 166 3.0E-44 T 12-10-2018 AFE_2621 9f9ad122f026653fb7fdb825ec420d14 198 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 164 6.2E-38 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_0918 3550581085f166a9db07d947d0471a28 200 Gene3D G3DSA:1.20.144.10 101 200 1.4E-21 T 12-10-2018 AFE_0918 3550581085f166a9db07d947d0471a28 200 SUPERFAMILY SSF48317 6 184 5.63E-30 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFE_0918 3550581085f166a9db07d947d0471a28 200 SMART SM00014 69 181 1.7E-12 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFE_0918 3550581085f166a9db07d947d0471a28 200 Pfam PF01569 PAP2 superfamily 71 183 2.6E-19 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFE_1770 f6ede7c9bd2b7f8eb944acc4beb8df09 278 Gene3D G3DSA:3.30.1300.10 178 278 1.8E-22 T 12-10-2018 AFE_1770 f6ede7c9bd2b7f8eb944acc4beb8df09 278 Pfam PF02569 Pantoate-beta-alanine ligase 3 275 2.7E-90 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFE_1770 f6ede7c9bd2b7f8eb944acc4beb8df09 278 SUPERFAMILY SSF52374 1 277 5.91E-93 T 12-10-2018 AFE_1770 f6ede7c9bd2b7f8eb944acc4beb8df09 278 Hamap MF_00158 Pantothenate synthetase [panC]. 2 277 35.634 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFE_1770 f6ede7c9bd2b7f8eb944acc4beb8df09 278 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 277 6.6E-82 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFE_1770 f6ede7c9bd2b7f8eb944acc4beb8df09 278 Gene3D G3DSA:3.40.50.620 1 177 1.8E-65 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_1752 c5dae5544520a33ed32ee38763e62539 392 SUPERFAMILY SSF46565 228 267 1.14E-5 T 12-10-2018 IPR036869 Chaperone J-domain superfamily AFE_1338 fac21bcc08c816f0c310c4d5124e7462 347 Gene3D G3DSA:1.20.144.10 159 331 1.5E-11 T 12-10-2018 AFE_1338 fac21bcc08c816f0c310c4d5124e7462 347 Pfam PF01569 PAP2 superfamily 203 328 9.1E-14 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFE_1338 fac21bcc08c816f0c310c4d5124e7462 347 SMART SM00014 199 324 4.8E-6 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFE_1338 fac21bcc08c816f0c310c4d5124e7462 347 SUPERFAMILY SSF48317 132 328 1.01E-22 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFE_1830 aede10ad4b2945ea945dc350fbe447da 217 Gene3D G3DSA:3.10.450.710 36 211 1.3E-41 T 12-10-2018 AFE_1830 aede10ad4b2945ea945dc350fbe447da 217 PIRSF PIRSF004649 14 216 6.0E-45 T 12-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC AFE_1830 aede10ad4b2945ea945dc350fbe447da 217 Pfam PF05494 MlaC protein 45 207 1.7E-43 T 12-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC AFE_2747 9a6ebf1c3600cecbba69b7b4a962ddfb 173 PIRSF PIRSF039093 1 173 2.8E-83 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AFE_2747 9a6ebf1c3600cecbba69b7b4a962ddfb 173 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 3 173 39.928 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AFE_2747 9a6ebf1c3600cecbba69b7b4a962ddfb 173 Pfam PF00227 Proteasome subunit 2 170 5.2E-23 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFE_2747 9a6ebf1c3600cecbba69b7b4a962ddfb 173 Gene3D G3DSA:3.60.20.10 1 173 1.5E-66 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_2747 9a6ebf1c3600cecbba69b7b4a962ddfb 173 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 4 173 1.1E-82 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AFE_2747 9a6ebf1c3600cecbba69b7b4a962ddfb 173 SUPERFAMILY SSF56235 1 172 7.53E-57 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFE_2728 95985a8b50b849887d422f50aa4a46c2 269 SUPERFAMILY SSF51735 15 247 2.65E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2728 95985a8b50b849887d422f50aa4a46c2 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_2728 95985a8b50b849887d422f50aa4a46c2 269 Pfam PF00106 short chain dehydrogenase 18 207 1.0E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2728 95985a8b50b849887d422f50aa4a46c2 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 2.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2728 95985a8b50b849887d422f50aa4a46c2 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2728 95985a8b50b849887d422f50aa4a46c2 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 2.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2728 95985a8b50b849887d422f50aa4a46c2 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 2.5E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_2728 95985a8b50b849887d422f50aa4a46c2 269 Gene3D G3DSA:3.40.50.720 6 250 3.9E-55 T 12-10-2018 AFE_2077 8a56241dcd0279d45c0400fcaa6badfc 164 Gene3D G3DSA:3.40.50.300 4 156 1.3E-47 T 12-10-2018 AFE_2077 8a56241dcd0279d45c0400fcaa6badfc 164 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 159 2.2E-36 T 12-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 AFE_2077 8a56241dcd0279d45c0400fcaa6badfc 164 Gene3D G3DSA:2.20.25.120 47 77 1.3E-47 T 12-10-2018 AFE_2077 8a56241dcd0279d45c0400fcaa6badfc 164 SUPERFAMILY SSF52540 1 160 3.48E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2077 8a56241dcd0279d45c0400fcaa6badfc 164 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 134 1.1E-39 T 12-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 AFE_2802 e401b1de1b82177a86f09de21f7418f7 109 Pfam PF00893 Small Multidrug Resistance protein 1 93 6.2E-32 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 AFE_2802 e401b1de1b82177a86f09de21f7418f7 109 Gene3D G3DSA:1.10.3730.20 1 109 1.6E-38 T 12-10-2018 AFE_2802 e401b1de1b82177a86f09de21f7418f7 109 SUPERFAMILY SSF103481 4 105 1.57E-21 T 12-10-2018 AFE_0019 7da20ad293e915f8868ad5a39b53e37c 167 Gene3D G3DSA:3.90.45.10 3 166 2.3E-59 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFE_0019 7da20ad293e915f8868ad5a39b53e37c 167 PIRSF PIRSF004749 1 165 1.3E-53 T 12-10-2018 IPR023635 Peptide deformylase AFE_0019 7da20ad293e915f8868ad5a39b53e37c 167 SUPERFAMILY SSF56420 3 163 4.45E-57 T 12-10-2018 IPR036821 Peptide deformylase superfamily AFE_0019 7da20ad293e915f8868ad5a39b53e37c 167 Pfam PF01327 Polypeptide deformylase 5 152 4.1E-49 T 12-10-2018 IPR023635 Peptide deformylase AFE_0019 7da20ad293e915f8868ad5a39b53e37c 167 Hamap MF_00163 Peptide deformylase [def]. 2 162 29.427 T 12-10-2018 IPR023635 Peptide deformylase AFE_0019 7da20ad293e915f8868ad5a39b53e37c 167 PRINTS PR01576 Peptide deformylase signature 89 100 9.2E-37 T 12-10-2018 IPR023635 Peptide deformylase AFE_0019 7da20ad293e915f8868ad5a39b53e37c 167 PRINTS PR01576 Peptide deformylase signature 101 119 9.2E-37 T 12-10-2018 IPR023635 Peptide deformylase AFE_0019 7da20ad293e915f8868ad5a39b53e37c 167 PRINTS PR01576 Peptide deformylase signature 120 149 9.2E-37 T 12-10-2018 IPR023635 Peptide deformylase AFE_0019 7da20ad293e915f8868ad5a39b53e37c 167 PRINTS PR01576 Peptide deformylase signature 33 62 9.2E-37 T 12-10-2018 IPR023635 Peptide deformylase AFE_0019 7da20ad293e915f8868ad5a39b53e37c 167 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 159 9.5E-54 T 12-10-2018 IPR023635 Peptide deformylase AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 Gene3D G3DSA:2.60.120.10 118 206 2.5E-17 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 SUPERFAMILY SSF54862 3 107 2.34E-23 T 12-10-2018 AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 Pfam PF00037 4Fe-4S binding domain 35 55 2.0E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 Pfam PF11953 Domain of unknown function (DUF3470) 66 102 4.3E-15 T 12-10-2018 IPR022569 Ferredoxin, C-terminal AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 SUPERFAMILY SSF51197 123 206 2.75E-23 T 12-10-2018 AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 Pfam PF09313 Domain of unknown function (DUF1971) 128 202 1.3E-19 T 12-10-2018 IPR015392 Domain of unknown function DUF1971 AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.7E-13 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.7E-13 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.7E-13 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 AFE_1844 d0ad41e12c20b87e665219d6060444ec 206 Gene3D G3DSA:3.30.70.20 2 102 3.5E-28 T 12-10-2018 AFE_0780 d2c164f905e7dc62527a7e3c06beacce 313 Pfam PF13478 XdhC Rossmann domain 165 303 6.1E-32 T 12-10-2018 IPR027051 XdhC Rossmann domain AFE_0780 d2c164f905e7dc62527a7e3c06beacce 313 Gene3D G3DSA:3.40.50.720 164 313 1.6E-35 T 12-10-2018 AFE_0780 d2c164f905e7dc62527a7e3c06beacce 313 Pfam PF02625 XdhC and CoxI family 16 57 1.5E-9 T 12-10-2018 IPR003777 XdhC- CoxI AFE_2297 a6dfc451ffad44de46541bece3871ca7 232 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 22 3.7E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AFE_2297 a6dfc451ffad44de46541bece3871ca7 232 Pfam PF04185 Phosphoesterase family 54 105 1.0E-11 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 AFE_2297 a6dfc451ffad44de46541bece3871ca7 232 Pfam PF04185 Phosphoesterase family 146 204 4.6E-18 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 AFE_2297 a6dfc451ffad44de46541bece3871ca7 232 Gene3D G3DSA:3.40.720.10 144 232 6.5E-24 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_2297 a6dfc451ffad44de46541bece3871ca7 232 Gene3D G3DSA:3.40.720.10 28 115 5.5E-9 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFE_2420 0b0e747276e7cd561bf0498dfd398fa4 333 SUPERFAMILY SSF161111 35 227 1.22E-49 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFE_2420 0b0e747276e7cd561bf0498dfd398fa4 333 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 36 307 8.5E-74 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFE_2420 0b0e747276e7cd561bf0498dfd398fa4 333 Gene3D G3DSA:1.20.1510.10 35 227 1.0E-39 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFE_2420 0b0e747276e7cd561bf0498dfd398fa4 333 Pfam PF01545 Cation efflux family 40 225 5.8E-41 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFE_2420 0b0e747276e7cd561bf0498dfd398fa4 333 SUPERFAMILY SSF160240 235 306 2.62E-8 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFE_0768 d719d77ec4e88a48747cdf10d8037d65 234 Pfam PF01618 MotA/TolQ/ExbB proton channel family 80 199 1.2E-25 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel AFE_0878 784a54e3e693b4461ab250fda473c963 170 Pfam PF00583 Acetyltransferase (GNAT) family 43 142 5.1E-13 T 12-10-2018 IPR000182 GNAT domain AFE_0878 784a54e3e693b4461ab250fda473c963 170 Gene3D G3DSA:3.40.630.30 2 169 1.3E-42 T 12-10-2018 AFE_0878 784a54e3e693b4461ab250fda473c963 170 SUPERFAMILY SSF55729 1 144 2.06E-29 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_1493 767c0cef24984d79fd29d4f73231bd27 239 Gene3D G3DSA:3.40.190.10 84 189 7.0E-49 T 12-10-2018 AFE_1493 767c0cef24984d79fd29d4f73231bd27 239 SUPERFAMILY SSF53850 5 226 2.56E-48 T 12-10-2018 AFE_1493 767c0cef24984d79fd29d4f73231bd27 239 PIRSF PIRSF004846 1 230 2.1E-45 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 AFE_1493 767c0cef24984d79fd29d4f73231bd27 239 Pfam PF13531 Bacterial extracellular solute-binding protein 5 226 2.9E-43 T 12-10-2018 AFE_1493 767c0cef24984d79fd29d4f73231bd27 239 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 13 222 4.5E-38 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 AFE_1493 767c0cef24984d79fd29d4f73231bd27 239 Gene3D G3DSA:3.40.190.10 8 226 7.0E-49 T 12-10-2018 AFE_2437 95d7f8feabcb4cbc0c196e3931ced749 84 Gene3D G3DSA:3.40.50.150 1 75 2.7E-8 T 12-10-2018 AFE_2437 95d7f8feabcb4cbc0c196e3931ced749 84 Pfam PF02353 Mycolic acid cyclopropane synthetase 4 60 1.5E-8 T 12-10-2018 AFE_2421 ac47d284b5c7f0eaa04a1b3f342dd988 158 Pfam PF13411 MerR HTH family regulatory protein 1 68 4.9E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_2421 ac47d284b5c7f0eaa04a1b3f342dd988 158 SMART SM00422 1 70 7.5E-27 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_2421 ac47d284b5c7f0eaa04a1b3f342dd988 158 SUPERFAMILY SSF46955 1 127 1.14E-34 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFE_2421 ac47d284b5c7f0eaa04a1b3f342dd988 158 Gene3D G3DSA:1.10.1660.10 1 125 1.7E-33 T 12-10-2018 AFE_2421 ac47d284b5c7f0eaa04a1b3f342dd988 158 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 127 5.2E-47 T 12-10-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 AFE_2421 ac47d284b5c7f0eaa04a1b3f342dd988 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.6E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_2421 ac47d284b5c7f0eaa04a1b3f342dd988 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.6E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_2421 ac47d284b5c7f0eaa04a1b3f342dd988 158 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.6E-9 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFE_1994 d9a4640538785059e00003aedb5e9dea 223 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 21 211 2.0E-70 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_1994 d9a4640538785059e00003aedb5e9dea 223 Gene3D G3DSA:3.90.870.10 3 220 1.8E-84 T 12-10-2018 AFE_1994 d9a4640538785059e00003aedb5e9dea 223 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 15 217 41.138 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_1994 d9a4640538785059e00003aedb5e9dea 223 SUPERFAMILY SSF55821 16 215 2.98E-81 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFE_1994 d9a4640538785059e00003aedb5e9dea 223 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 22 211 2.8E-80 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFE_2133 e6322cbe0075d5c265c9dd8869c8ae07 160 Gene3D G3DSA:3.40.50.620 11 157 1.8E-35 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_2133 e6322cbe0075d5c265c9dd8869c8ae07 160 Pfam PF00582 Universal stress protein family 13 156 2.9E-28 T 12-10-2018 IPR006016 UspA AFE_2133 e6322cbe0075d5c265c9dd8869c8ae07 160 PIRSF PIRSF006276 11 159 1.4E-18 T 12-10-2018 IPR006015 Universal stress protein A AFE_2133 e6322cbe0075d5c265c9dd8869c8ae07 160 PRINTS PR01438 Universal stress protein signature 12 30 6.6E-18 T 12-10-2018 IPR006015 Universal stress protein A AFE_2133 e6322cbe0075d5c265c9dd8869c8ae07 160 PRINTS PR01438 Universal stress protein signature 134 156 6.6E-18 T 12-10-2018 IPR006015 Universal stress protein A AFE_2133 e6322cbe0075d5c265c9dd8869c8ae07 160 PRINTS PR01438 Universal stress protein signature 116 128 6.6E-18 T 12-10-2018 IPR006015 Universal stress protein A AFE_2133 e6322cbe0075d5c265c9dd8869c8ae07 160 SUPERFAMILY SSF52402 12 158 5.11E-36 T 12-10-2018 AFE_0114 630bb656f8433e65d086b89a4aa10bf7 339 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 88 103 - T 12-10-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0016787 Reactome: R-HSA-163560 AFE_0114 630bb656f8433e65d086b89a4aa10bf7 339 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 159 171 - T 12-10-2018 IPR033140 Lipase, GDXG, putative serine active site AFE_0114 630bb656f8433e65d086b89a4aa10bf7 339 Gene3D G3DSA:3.40.50.1820 33 334 2.0E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_0114 630bb656f8433e65d086b89a4aa10bf7 339 SUPERFAMILY SSF53474 26 324 1.09E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_0114 630bb656f8433e65d086b89a4aa10bf7 339 Pfam PF07859 alpha/beta hydrolase fold 88 292 9.6E-26 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AFE_1720 61ea56f07d26fbaef9a7639c3b1eda41 256 SUPERFAMILY SSF52540 1 244 4.68E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1720 61ea56f07d26fbaef9a7639c3b1eda41 256 Gene3D G3DSA:3.40.50.300 1 251 1.4E-42 T 12-10-2018 AFE_1720 61ea56f07d26fbaef9a7639c3b1eda41 256 Pfam PF13614 AAA domain 3 166 3.0E-25 T 12-10-2018 IPR025669 AAA domain AFE_0282 dfa812d4f9af529c566afd92f6edadb0 158 Gene3D G3DSA:3.30.1490.190 89 141 1.6E-20 T 12-10-2018 AFE_0282 dfa812d4f9af529c566afd92f6edadb0 158 Pfam PF01475 Ferric uptake regulator family 14 133 1.8E-42 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFE_0282 dfa812d4f9af529c566afd92f6edadb0 158 SUPERFAMILY SSF46785 9 136 3.36E-41 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0282 dfa812d4f9af529c566afd92f6edadb0 158 Gene3D G3DSA:1.10.10.10 4 87 2.6E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0720 9e38f335c066c73a6cccc7f1125ca529 416 SUPERFAMILY SSF54373 271 359 1.83E-10 T 12-10-2018 AFE_0720 9e38f335c066c73a6cccc7f1125ca529 416 Gene3D G3DSA:3.30.9.10 137 358 3.8E-46 T 12-10-2018 AFE_0720 9e38f335c066c73a6cccc7f1125ca529 416 Gene3D G3DSA:3.50.50.60 93 398 3.8E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0720 9e38f335c066c73a6cccc7f1125ca529 416 Pfam PF01266 FAD dependent oxidoreductase 6 398 1.4E-55 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFE_0720 9e38f335c066c73a6cccc7f1125ca529 416 SUPERFAMILY SSF51905 6 416 6.47E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_0720 9e38f335c066c73a6cccc7f1125ca529 416 Gene3D G3DSA:3.50.50.60 1 82 2.8E-11 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFE_1888 e46ba4f0d25e793148b28a46da833885 400 SUPERFAMILY SSF55681 10 334 7.11E-49 T 12-10-2018 AFE_1888 e46ba4f0d25e793148b28a46da833885 400 Pfam PF13393 Histidyl-tRNA synthetase 15 325 7.6E-106 T 12-10-2018 AFE_1888 e46ba4f0d25e793148b28a46da833885 400 PIRSF PIRSF001549 10 355 8.9E-44 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AFE_1888 e46ba4f0d25e793148b28a46da833885 400 Gene3D G3DSA:3.30.930.10 9 334 1.8E-65 T 12-10-2018 AFE_1888 e46ba4f0d25e793148b28a46da833885 400 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 22 376 28.527 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 AFE_0577 7d73b30a6e83826c4a721c458c0b8b33 359 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 46 323 4.5E-17 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFE_0577 7d73b30a6e83826c4a721c458c0b8b33 359 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 46 335 2.4E-45 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFE_2172 a5d0855f55a590cf1bf1343343267374 428 Gene3D G3DSA:3.40.710.10 11 371 1.3E-98 T 12-10-2018 AFE_2172 a5d0855f55a590cf1bf1343343267374 428 Pfam PF00144 Beta-lactamase 30 355 9.9E-77 T 12-10-2018 IPR001466 Beta-lactamase-related AFE_2172 a5d0855f55a590cf1bf1343343267374 428 SUPERFAMILY SSF56601 24 366 1.38E-92 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_2245 808ccc9a3af2fa5d64f0a13ef1d92d38 397 Gene3D G3DSA:1.20.1530.20 5 396 3.7E-12 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily AFE_2245 808ccc9a3af2fa5d64f0a13ef1d92d38 397 Pfam PF00999 Sodium/hydrogen exchanger family 8 394 3.2E-65 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFE_0623 520517414b434ddc3967f9d40081ca93 254 Pfam PF08241 Methyltransferase domain 46 142 9.2E-24 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFE_0623 520517414b434ddc3967f9d40081ca93 254 Gene3D G3DSA:3.40.50.150 22 249 1.1E-59 T 12-10-2018 AFE_0623 520517414b434ddc3967f9d40081ca93 254 SUPERFAMILY SSF53335 23 234 4.6E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0431 7e0e518ec459dd88e56f9aeadcf78908 319 SUPERFAMILY SSF55120 76 313 3.91E-77 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0431 7e0e518ec459dd88e56f9aeadcf78908 319 Gene3D G3DSA:3.30.2350.10 85 316 8.0E-72 T 12-10-2018 AFE_0431 7e0e518ec459dd88e56f9aeadcf78908 319 SUPERFAMILY SSF55174 19 103 1.18E-10 T 12-10-2018 AFE_0431 7e0e518ec459dd88e56f9aeadcf78908 319 Pfam PF01479 S4 domain 19 65 1.8E-10 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0431 7e0e518ec459dd88e56f9aeadcf78908 319 Pfam PF00849 RNA pseudouridylate synthase 92 241 3.7E-30 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0431 7e0e518ec459dd88e56f9aeadcf78908 319 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0431 7e0e518ec459dd88e56f9aeadcf78908 319 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 14 312 1.9E-93 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFE_0431 7e0e518ec459dd88e56f9aeadcf78908 319 Gene3D G3DSA:3.10.290.10 8 73 1.4E-19 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFE_0431 7e0e518ec459dd88e56f9aeadcf78908 319 SMART SM00363 19 83 6.7E-9 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_2826 bca861637fe488550b1259eaa10270b9 713 Gene3D G3DSA:1.20.1740.10 32 486 8.4E-20 T 12-10-2018 AFE_2826 bca861637fe488550b1259eaa10270b9 713 Pfam PF13520 Amino acid permease 45 460 5.4E-23 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_0648 9ae2631ad318230314ce6d8927c22523 378 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 120 373 1.7E-66 T 12-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria AFE_0648 9ae2631ad318230314ce6d8927c22523 378 Pfam PF02405 Permease MlaE 162 369 3.0E-65 T 12-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 AFE_2234 d9343ca0b26c9edcfa4aba563253c4a4 206 PIRSF PIRSF001296 1 192 2.8E-74 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFE_2234 d9343ca0b26c9edcfa4aba563253c4a4 206 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 189 34.567 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFE_2234 d9343ca0b26c9edcfa4aba563253c4a4 206 Pfam PF02669 K+-transporting ATPase, c chain 6 187 4.5E-73 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFE_2234 d9343ca0b26c9edcfa4aba563253c4a4 206 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 4 187 1.4E-71 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFE_1621 c477c69e108d2fb18916bd01559998fc 516 Pfam PF11843 Protein of unknown function (DUF3363) 303 405 1.0E-12 T 12-10-2018 IPR021795 Protein of unknown function DUF3363 AFE_0503 729ae8d8c80e513ea6ff8e1e278ed323 46 Pfam PF13711 Domain of unknown function (DUF4160) 9 28 6.2E-5 T 12-10-2018 IPR025427 Protein of unknown function DUF4160 AFE_2567 bf034b4c6c8cbffa9cc484f7d74c7f12 388 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 46 262 7.8E-67 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 AFE_2567 bf034b4c6c8cbffa9cc484f7d74c7f12 388 SUPERFAMILY SSF69189 286 375 7.65E-13 T 12-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_2567 bf034b4c6c8cbffa9cc484f7d74c7f12 388 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 284 373 4.0E-14 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_2567 bf034b4c6c8cbffa9cc484f7d74c7f12 388 Gene3D G3DSA:2.60.410.10 283 373 8.5E-17 T 12-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_2567 bf034b4c6c8cbffa9cc484f7d74c7f12 388 Gene3D G3DSA:3.40.710.10 29 281 3.5E-79 T 12-10-2018 AFE_2567 bf034b4c6c8cbffa9cc484f7d74c7f12 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 123 140 3.9E-17 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFE_2567 bf034b4c6c8cbffa9cc484f7d74c7f12 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 3.9E-17 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFE_2567 bf034b4c6c8cbffa9cc484f7d74c7f12 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 150 163 3.9E-17 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFE_2567 bf034b4c6c8cbffa9cc484f7d74c7f12 388 SMART SM00936 283 373 1.8E-14 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFE_2567 bf034b4c6c8cbffa9cc484f7d74c7f12 388 SUPERFAMILY SSF56601 8 283 5.33E-72 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFE_1088 d801a406fc65e33cd3a4e3ee0f2eb34c 254 Gene3D G3DSA:3.40.30.10 68 243 5.3E-25 T 12-10-2018 AFE_1088 d801a406fc65e33cd3a4e3ee0f2eb34c 254 SUPERFAMILY SSF52833 68 233 3.6E-21 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1375 81111b71183d51cfc96fba223405a835 70 Pfam PF17342 Family of unknown function (DUF5372) 2 63 8.3E-20 T 12-10-2018 IPR035315 Protein of unknown function DUF5372 AFE_1375 81111b71183d51cfc96fba223405a835 70 ProDom PD027658 PLASMID ISRM30 TRANSPOSASE FOR Y4BD/Y4PK Y4ON NUMBER SEQUENCE INSERTION 14 64 2.0E-9 T 12-10-2018 IPR035315 Protein of unknown function DUF5372 AFE_2977 9cef0898cd6bbb566cc2cc2abd21e38c 339 Gene3D G3DSA:3.40.50.720 5 320 9.0E-146 T 12-10-2018 AFE_2977 9cef0898cd6bbb566cc2cc2abd21e38c 339 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 329 9.8E-131 T 12-10-2018 IPR016040 NAD(P)-binding domain AFE_2977 9cef0898cd6bbb566cc2cc2abd21e38c 339 SUPERFAMILY SSF51735 3 334 1.02E-65 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_2977 9cef0898cd6bbb566cc2cc2abd21e38c 339 Gene3D G3DSA:3.90.25.10 186 334 9.0E-146 T 12-10-2018 AFE_2977 9cef0898cd6bbb566cc2cc2abd21e38c 339 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 336 1.3E-136 T 12-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 AFE_2977 9cef0898cd6bbb566cc2cc2abd21e38c 339 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 339 51.087 T 12-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 AFE_0236 58e49d2fffc9ef25969ae7682851d6cd 226 SUPERFAMILY SSF52799 32 166 8.49E-20 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like AFE_0236 58e49d2fffc9ef25969ae7682851d6cd 226 Gene3D G3DSA:3.90.190.10 31 177 7.0E-23 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like AFE_0236 58e49d2fffc9ef25969ae7682851d6cd 226 Pfam PF13350 Tyrosine phosphatase family 42 145 2.3E-5 T 12-10-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type AFE_0306 4ff9752dc981bea295aa8132e4010ccc 217 Gene3D G3DSA:3.30.1330.60 90 215 3.1E-32 T 12-10-2018 IPR036737 OmpA-like domain superfamily AFE_0306 4ff9752dc981bea295aa8132e4010ccc 217 PRINTS PR01021 OMPA domain signature 153 169 2.1E-10 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFE_0306 4ff9752dc981bea295aa8132e4010ccc 217 PRINTS PR01021 OMPA domain signature 138 153 2.1E-10 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFE_0306 4ff9752dc981bea295aa8132e4010ccc 217 PRINTS PR01021 OMPA domain signature 108 130 2.1E-10 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 AFE_0306 4ff9752dc981bea295aa8132e4010ccc 217 Pfam PF00691 OmpA family 107 201 9.1E-18 T 12-10-2018 IPR006665 OmpA-like domain AFE_0306 4ff9752dc981bea295aa8132e4010ccc 217 SUPERFAMILY SSF103088 79 206 3.4E-31 T 12-10-2018 IPR036737 OmpA-like domain superfamily AFE_1821 57c231f3076fdc06ce31fffa868cc365 406 Gene3D G3DSA:3.40.640.10 47 293 3.5E-109 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_1821 57c231f3076fdc06ce31fffa868cc365 406 Gene3D G3DSA:3.90.1150.10 18 382 3.5E-109 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_1821 57c231f3076fdc06ce31fffa868cc365 406 SUPERFAMILY SSF53383 6 397 9.63E-81 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_1821 57c231f3076fdc06ce31fffa868cc365 406 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 6 395 2.9E-182 T 12-10-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 AFE_1821 57c231f3076fdc06ce31fffa868cc365 406 Pfam PF00155 Aminotransferase class I and II 35 391 1.5E-35 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFE_1750 96a37d162afa5ffa545484a003aa0c99 164 SUPERFAMILY SSF51306 44 162 1.19E-35 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFE_1750 96a37d162afa5ffa545484a003aa0c99 164 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 116 128 2.7E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFE_1750 96a37d162afa5ffa545484a003aa0c99 164 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 88 99 2.7E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFE_1750 96a37d162afa5ffa545484a003aa0c99 164 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 77 87 2.7E-9 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFE_1750 96a37d162afa5ffa545484a003aa0c99 164 Pfam PF00717 Peptidase S24-like 80 145 1.6E-11 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFE_1750 96a37d162afa5ffa545484a003aa0c99 164 Gene3D G3DSA:2.10.109.10 50 164 1.4E-41 T 12-10-2018 AFE_2154 ff959099ec0f16129c43c450fb114e0c 165 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 47 157 7.3E-25 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2154 ff959099ec0f16129c43c450fb114e0c 165 Gene3D G3DSA:3.40.50.12280 30 165 7.8E-46 T 12-10-2018 AFE_2154 ff959099ec0f16129c43c450fb114e0c 165 SUPERFAMILY SSF56770 29 160 2.88E-47 T 12-10-2018 AFE_0858 ceb6ac1211d8b8f10132957cfbf666e7 130 Pfam PF04343 Protein of unknown function, DUF488 15 119 2.5E-25 T 12-10-2018 IPR007438 Protein of unknown function DUF488 AFE_3220 7ffd6e9653eccb43bca2d79ed129042b 299 Pfam PF01544 CorA-like Mg2+ transporter protein 81 287 6.1E-15 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFE_0672 e0684ad8b4936733ec9ca78042d28ee9 162 Gene3D G3DSA:1.10.10.10 1 145 6.7E-48 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_0672 e0684ad8b4936733ec9ca78042d28ee9 162 Pfam PF02082 Transcriptional regulator 1 83 8.0E-27 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type AFE_0672 e0684ad8b4936733ec9ca78042d28ee9 162 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site AFE_0672 e0684ad8b4936733ec9ca78042d28ee9 162 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 133 6.7E-43 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type AFE_0672 e0684ad8b4936733ec9ca78042d28ee9 162 SUPERFAMILY SSF46785 2 135 1.92E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_0137 468d51d9dbe7e5e5a4f19d480b24ed8a 447 Pfam PF03573 outer membrane porin, OprD family 29 272 1.0E-12 T 12-10-2018 IPR005318 Outer membrane porin, bacterial GO:0016021 AFE_0137 468d51d9dbe7e5e5a4f19d480b24ed8a 447 Gene3D G3DSA:2.40.160.10 33 344 2.3E-26 T 12-10-2018 IPR023614 Porin domain superfamily AFE_2954 ef713afbfed583d8e86b795b146a29a1 496 Gene3D G3DSA:3.40.1260.20 409 496 2.9E-7 T 12-10-2018 AFE_2954 ef713afbfed583d8e86b795b146a29a1 496 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 433 3.5E-157 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 AFE_2954 ef713afbfed583d8e86b795b146a29a1 496 Gene3D G3DSA:2.40.50.140 32 133 7.0E-30 T 12-10-2018 AFE_2954 ef713afbfed583d8e86b795b146a29a1 496 SMART SM00316 37 127 2.6E-10 T 12-10-2018 IPR022967 RNA-binding domain, S1 AFE_2954 ef713afbfed583d8e86b795b146a29a1 496 Pfam PF10150 Ribonuclease E/G family 129 400 9.9E-101 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 AFE_2954 ef713afbfed583d8e86b795b146a29a1 496 Pfam PF00575 S1 RNA binding domain 38 127 3.7E-7 T 12-10-2018 IPR003029 S1 domain GO:0003676 AFE_2954 ef713afbfed583d8e86b795b146a29a1 496 SUPERFAMILY SSF50249 39 133 6.59E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_2586 c4e64f20715de5efbed53e4733a592e8 450 Pfam PF02754 Cysteine-rich domain 255 354 6.5E-7 T 12-10-2018 IPR004017 Cysteine-rich domain AFE_3307 1476316254b75d59670295a55297277a 261 Gene3D G3DSA:3.40.50.720 3 250 4.7E-57 T 12-10-2018 AFE_3307 1476316254b75d59670295a55297277a 261 Pfam PF00106 short chain dehydrogenase 4 191 3.0E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3307 1476316254b75d59670295a55297277a 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 186 0.0044 T 12-10-2018 AFE_3307 1476316254b75d59670295a55297277a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3307 1476316254b75d59670295a55297277a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3307 1476316254b75d59670295a55297277a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3307 1476316254b75d59670295a55297277a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3307 1476316254b75d59670295a55297277a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.8E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3307 1476316254b75d59670295a55297277a 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFE_3307 1476316254b75d59670295a55297277a 261 SUPERFAMILY SSF51735 5 247 2.37E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily AFE_3307 1476316254b75d59670295a55297277a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3307 1476316254b75d59670295a55297277a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_3307 1476316254b75d59670295a55297277a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.9E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFE_1114 a8f369542e1c66739a18e3725e030379 273 Pfam PF01435 Peptidase family M48 74 272 2.6E-34 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFE_1114 a8f369542e1c66739a18e3725e030379 273 Gene3D G3DSA:3.30.2010.10 64 156 8.1E-26 T 12-10-2018 AFE_0787 34e373a98ab26807a051248764beb99d 349 Gene3D G3DSA:3.20.20.370 137 348 2.2E-47 T 12-10-2018 AFE_0787 34e373a98ab26807a051248764beb99d 349 Pfam PF01522 Polysaccharide deacetylase 151 269 6.1E-23 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFE_0787 34e373a98ab26807a051248764beb99d 349 SUPERFAMILY SSF88713 147 341 2.0E-47 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFE_1336 d8dc7189e55dd7e5ae7f9548ee76abad 72 Pfam PF11154 Protein of unknown function (DUF2934) 24 57 1.6E-10 T 12-10-2018 IPR021327 Protein of unknown function DUF2934 AFE_0537 0ddc1234a2695088ef3ae9221070f5b9 293 Pfam PF01569 PAP2 superfamily 208 285 9.7E-13 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFE_0537 0ddc1234a2695088ef3ae9221070f5b9 293 SUPERFAMILY SSF48317 107 284 8.5E-5 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFE_0537 0ddc1234a2695088ef3ae9221070f5b9 293 SMART SM00014 163 283 0.0039 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFE_0537 0ddc1234a2695088ef3ae9221070f5b9 293 Gene3D G3DSA:1.20.144.10 197 290 4.4E-10 T 12-10-2018 AFE_1945 a2184ba4e00e78112e34323ca3a7df01 252 Pfam PF01925 Sulfite exporter TauE/SafE 14 250 6.6E-34 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFE_2121 55530c343c0e9305019f2ccced386ae9 386 TIGRFAM TIGR03472 HpnI: hopanoid biosynthesis associated glycosyl transferase protein HpnI 2 380 2.6E-151 T 12-10-2018 IPR017835 Hopanoid biosynthesis associated glycosyltransferase, HpnI AFE_2121 55530c343c0e9305019f2ccced386ae9 386 Pfam PF13506 Glycosyl transferase family 21 108 279 9.3E-41 T 12-10-2018 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|MetaCyc: PWY-7836|MetaCyc: PWY-7838|MetaCyc: PWY-7839|MetaCyc: PWY-7841|Reactome: R-HSA-1660662 AFE_2121 55530c343c0e9305019f2ccced386ae9 386 Gene3D G3DSA:3.90.550.10 47 260 5.9E-14 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2121 55530c343c0e9305019f2ccced386ae9 386 SUPERFAMILY SSF53448 52 294 6.0E-29 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0678 f6f4e209a0bd4a3869a65fb21cd3dd36 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 12-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 AFE_0678 f6f4e209a0bd4a3869a65fb21cd3dd36 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 92 5.5E-15 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFE_0678 f6f4e209a0bd4a3869a65fb21cd3dd36 112 SUPERFAMILY SSF54292 8 104 7.9E-30 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFE_0678 f6f4e209a0bd4a3869a65fb21cd3dd36 112 Gene3D G3DSA:3.10.20.30 1 112 4.9E-34 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_0678 f6f4e209a0bd4a3869a65fb21cd3dd36 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 3 110 1.0E-50 T 12-10-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 AFE_0678 f6f4e209a0bd4a3869a65fb21cd3dd36 112 PRINTS PR00355 Adrenodoxin signature 83 91 8.8E-9 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 AFE_0678 f6f4e209a0bd4a3869a65fb21cd3dd36 112 PRINTS PR00355 Adrenodoxin signature 60 74 8.8E-9 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 AFE_0678 f6f4e209a0bd4a3869a65fb21cd3dd36 112 PRINTS PR00355 Adrenodoxin signature 42 52 8.8E-9 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 AFE_1642 54c288057238f7441ed34e2f3602185b 589 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 77 298 1.7E-10 T 12-10-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 AFE_1642 54c288057238f7441ed34e2f3602185b 589 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 25 365 1.6E-108 T 12-10-2018 IPR014150 Conjugal transfer, TrbL AFE_1065 b14ef5b46c65790802d1ae8f70d7f954 196 Gene3D G3DSA:1.10.530.10 50 173 4.2E-14 T 12-10-2018 AFE_1065 b14ef5b46c65790802d1ae8f70d7f954 196 Pfam PF01464 Transglycosylase SLT domain 51 158 2.5E-12 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 AFE_1065 b14ef5b46c65790802d1ae8f70d7f954 196 SUPERFAMILY SSF53955 22 167 1.01E-19 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily AFE_1227 2410cfac3f8b6103cd0d8e16f1ab6940 371 SUPERFAMILY SSF56300 1 285 1.34E-35 T 12-10-2018 AFE_1227 2410cfac3f8b6103cd0d8e16f1ab6940 371 Pfam PF00149 Calcineurin-like phosphoesterase 1 92 5.2E-8 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFE_1227 2410cfac3f8b6103cd0d8e16f1ab6940 371 PIRSF PIRSF033093 1 371 1.7E-99 T 12-10-2018 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type AFE_1227 2410cfac3f8b6103cd0d8e16f1ab6940 371 Gene3D G3DSA:3.60.21.10 1 239 2.0E-28 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like AFE_3105 cda9f21e497fde9427e2b9a79a8a8ae1 101 Pfam PF13358 DDE superfamily endonuclease 30 86 5.5E-7 T 12-10-2018 IPR038717 Tc1-like transposase, DDE domain AFE_1425 9ab1348b6b0b5b1b65c4c254c1ebc033 373 SUPERFAMILY SSF53756 2 364 7.73E-75 T 12-10-2018 AFE_1425 9ab1348b6b0b5b1b65c4c254c1ebc033 373 Pfam PF00534 Glycosyl transferases group 1 184 344 3.2E-28 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_1425 9ab1348b6b0b5b1b65c4c254c1ebc033 373 Gene3D G3DSA:3.40.50.2000 173 349 7.8E-66 T 12-10-2018 AFE_1425 9ab1348b6b0b5b1b65c4c254c1ebc033 373 Gene3D G3DSA:3.40.50.2000 5 172 7.8E-66 T 12-10-2018 AFE_1425 9ab1348b6b0b5b1b65c4c254c1ebc033 373 Pfam PF13439 Glycosyltransferase Family 4 14 174 1.5E-25 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFE_0471 3c75c7581c0e9e7ce16bcc9d8a6f0927 124 SUPERFAMILY SSF64076 1 122 8.37E-31 T 12-10-2018 IPR036748 MTH938-like superfamily AFE_0471 3c75c7581c0e9e7ce16bcc9d8a6f0927 124 Gene3D G3DSA:3.40.1230.10 1 123 2.2E-37 T 12-10-2018 IPR036748 MTH938-like superfamily AFE_0471 3c75c7581c0e9e7ce16bcc9d8a6f0927 124 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 14 120 3.9E-27 T 12-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein AFE_2113 e3e53ba4d2bef9b9c8be383a1a594c24 279 Pfam PF04333 MlaA lipoprotein 36 227 5.0E-67 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 AFE_2113 e3e53ba4d2bef9b9c8be383a1a594c24 279 PRINTS PR01805 VacJ lipoprotein signature 37 50 4.5E-26 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 AFE_2113 e3e53ba4d2bef9b9c8be383a1a594c24 279 PRINTS PR01805 VacJ lipoprotein signature 105 122 4.5E-26 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 AFE_2113 e3e53ba4d2bef9b9c8be383a1a594c24 279 PRINTS PR01805 VacJ lipoprotein signature 54 70 4.5E-26 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 AFE_2113 e3e53ba4d2bef9b9c8be383a1a594c24 279 PRINTS PR01805 VacJ lipoprotein signature 141 158 4.5E-26 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 AFE_1787 819dd16ebd4aa81e2696abfe219701ee 211 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 8 200 2.6E-53 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFE_1787 819dd16ebd4aa81e2696abfe219701ee 211 Gene3D G3DSA:3.90.870.10 2 205 4.6E-59 T 12-10-2018 AFE_1787 819dd16ebd4aa81e2696abfe219701ee 211 Pfam PF01300 Telomere recombination 22 198 4.9E-41 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 AFE_1787 819dd16ebd4aa81e2696abfe219701ee 211 SUPERFAMILY SSF55821 1 202 2.29E-56 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFE_1547 257b993b0de89b2d1bba636bab6ffbc7 472 Pfam PF07690 Major Facilitator Superfamily 45 418 4.1E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_1547 257b993b0de89b2d1bba636bab6ffbc7 472 Gene3D G3DSA:1.20.1250.20 34 211 1.6E-10 T 12-10-2018 AFE_1547 257b993b0de89b2d1bba636bab6ffbc7 472 Gene3D G3DSA:1.20.1250.20 271 451 1.8E-12 T 12-10-2018 AFE_1547 257b993b0de89b2d1bba636bab6ffbc7 472 SUPERFAMILY SSF103473 36 448 4.19E-31 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_2978 6e10ccec37a6a7e10faefab73587970c 230 SUPERFAMILY SSF53335 28 211 4.87E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2978 6e10ccec37a6a7e10faefab73587970c 230 Pfam PF13649 Methyltransferase domain 49 142 8.4E-17 T 12-10-2018 AFE_2978 6e10ccec37a6a7e10faefab73587970c 230 Gene3D G3DSA:3.40.50.150 22 216 2.6E-26 T 12-10-2018 AFE_1784 178ff5a42cad09b42abeced29fa93321 891 Gene3D G3DSA:3.30.70.100 770 867 1.5E-8 T 12-10-2018 AFE_1784 178ff5a42cad09b42abeced29fa93321 891 SUPERFAMILY SSF82861 618 701 1.7E-10 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AFE_1784 178ff5a42cad09b42abeced29fa93321 891 SUPERFAMILY SSF50182 702 767 7.85E-19 T 12-10-2018 IPR010920 LSM domain superfamily AFE_1784 178ff5a42cad09b42abeced29fa93321 891 Gene3D G3DSA:2.30.30.60 718 767 6.7E-15 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily AFE_1784 178ff5a42cad09b42abeced29fa93321 891 SUPERFAMILY SSF82689 771 873 1.7E-13 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AFE_1784 178ff5a42cad09b42abeced29fa93321 891 Pfam PF00924 Mechanosensitive ion channel 661 862 7.9E-47 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFE_0657 1927b75a5f9622fa19aa7cd34b36e4e9 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFE_0657 1927b75a5f9622fa19aa7cd34b36e4e9 108 Pfam PF00085 Thioredoxin 6 106 6.2E-34 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFE_0657 1927b75a5f9622fa19aa7cd34b36e4e9 108 PRINTS PR00421 Thioredoxin family signature 24 32 3.3E-10 T 12-10-2018 AFE_0657 1927b75a5f9622fa19aa7cd34b36e4e9 108 PRINTS PR00421 Thioredoxin family signature 72 83 3.3E-10 T 12-10-2018 AFE_0657 1927b75a5f9622fa19aa7cd34b36e4e9 108 PRINTS PR00421 Thioredoxin family signature 32 41 3.3E-10 T 12-10-2018 AFE_0657 1927b75a5f9622fa19aa7cd34b36e4e9 108 PIRSF PIRSF000077 2 108 5.6E-44 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFE_0657 1927b75a5f9622fa19aa7cd34b36e4e9 108 SUPERFAMILY SSF52833 3 108 1.04E-39 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0657 1927b75a5f9622fa19aa7cd34b36e4e9 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 2.1E-38 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFE_0657 1927b75a5f9622fa19aa7cd34b36e4e9 108 Gene3D G3DSA:3.40.30.10 1 107 6.4E-36 T 12-10-2018 AFE_1898 34f28b6728bf94a1f3010a452562b3cb 205 SUPERFAMILY SSF46609 10 84 1.19E-11 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFE_1898 34f28b6728bf94a1f3010a452562b3cb 205 SUPERFAMILY SSF54719 92 198 1.7E-23 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFE_1898 34f28b6728bf94a1f3010a452562b3cb 205 Gene3D G3DSA:2.40.500.20 85 203 9.0E-23 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFE_1898 34f28b6728bf94a1f3010a452562b3cb 205 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 95 192 7.1E-16 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFE_1053 c7ddce0b2156758d75fb8c5d998397b8 574 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 19 201 1.6E-12 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 AFE_1053 c7ddce0b2156758d75fb8c5d998397b8 574 Gene3D G3DSA:3.40.50.620 2 204 4.8E-35 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFE_1053 c7ddce0b2156758d75fb8c5d998397b8 574 SUPERFAMILY SSF52402 15 201 6.05E-22 T 12-10-2018 AFE_3141 2b6a710a6d4bc91d24d3a465c8ac2fef 146 Gene3D G3DSA:1.10.10.10 1 138 1.5E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_3141 2b6a710a6d4bc91d24d3a465c8ac2fef 146 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site AFE_3141 2b6a710a6d4bc91d24d3a465c8ac2fef 146 Pfam PF02082 Transcriptional regulator 1 82 1.8E-18 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type AFE_3141 2b6a710a6d4bc91d24d3a465c8ac2fef 146 SUPERFAMILY SSF46785 2 131 4.55E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_3141 2b6a710a6d4bc91d24d3a465c8ac2fef 146 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 128 6.2E-29 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type AFE_0810 524117643e2c9f8bf58dff78459a8516 175 Gene3D G3DSA:3.10.20.30 19 96 4.0E-24 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_0810 524117643e2c9f8bf58dff78459a8516 175 SUPERFAMILY SSF54292 22 108 1.31E-19 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFE_0810 524117643e2c9f8bf58dff78459a8516 175 SUPERFAMILY SSF47741 105 171 2.49E-31 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily AFE_0810 524117643e2c9f8bf58dff78459a8516 175 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 28 77 3.7E-4 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AFE_0810 524117643e2c9f8bf58dff78459a8516 175 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AFE_0810 524117643e2c9f8bf58dff78459a8516 175 Pfam PF01799 [2Fe-2S] binding domain 94 166 6.0E-30 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 AFE_0810 524117643e2c9f8bf58dff78459a8516 175 Gene3D G3DSA:1.10.150.120 97 175 1.0E-31 T 12-10-2018 AFE_2563 672421d9f99f27130ff10c04400b2953 279 Gene3D G3DSA:2.40.10.340 119 265 6.5E-29 T 12-10-2018 AFE_2563 672421d9f99f27130ff10c04400b2953 279 PIRSF PIRSF038471 5 279 3.8E-54 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 AFE_2563 672421d9f99f27130ff10c04400b2953 279 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 44 269 4.3E-42 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 AFE_2563 672421d9f99f27130ff10c04400b2953 279 Pfam PF04085 rod shape-determining protein MreC 121 267 1.9E-28 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 AFE_2563 672421d9f99f27130ff10c04400b2953 279 Gene3D G3DSA:2.40.10.350 178 255 6.5E-29 T 12-10-2018 AFE_0647 cd0783ddeb3426ca447dd78b2b6f9b3f 205 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 9 203 5.0E-61 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like AFE_0647 cd0783ddeb3426ca447dd78b2b6f9b3f 205 SUPERFAMILY SSF52507 9 205 8.5E-57 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFE_0647 cd0783ddeb3426ca447dd78b2b6f9b3f 205 Pfam PF02441 Flavoprotein 9 184 5.7E-26 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFE_0647 cd0783ddeb3426ca447dd78b2b6f9b3f 205 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 8 205 35.035 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like AFE_0647 cd0783ddeb3426ca447dd78b2b6f9b3f 205 Gene3D G3DSA:3.40.50.1950 5 205 3.9E-80 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFE_1486 95ec31afdaa270ea91ecfd5d5e7b7a80 131 Gene3D G3DSA:3.30.420.270 57 124 4.9E-9 T 12-10-2018 AFE_1486 95ec31afdaa270ea91ecfd5d5e7b7a80 131 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 127 3.3E-26 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 AFE_3216 071ec4d7fc3631c2c4167888fc6b297d 179 Pfam PF13649 Methyltransferase domain 42 126 1.4E-10 T 12-10-2018 AFE_3216 071ec4d7fc3631c2c4167888fc6b297d 179 Gene3D G3DSA:3.40.50.150 9 175 6.3E-29 T 12-10-2018 AFE_3216 071ec4d7fc3631c2c4167888fc6b297d 179 SUPERFAMILY SSF53335 8 176 6.27E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_1362 4d744dd08203df317ac62af76e90660a 142 Pfam PF01850 PIN domain 2 124 4.3E-11 T 12-10-2018 IPR002716 PIN domain AFE_1362 4d744dd08203df317ac62af76e90660a 142 SUPERFAMILY SSF88723 1 140 7.85E-30 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_1362 4d744dd08203df317ac62af76e90660a 142 Gene3D G3DSA:3.40.50.1010 1 140 1.5E-38 T 12-10-2018 AFE_1362 4d744dd08203df317ac62af76e90660a 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 136 11.978 T 12-10-2018 IPR022907 VapC family GO:0004540 AFE_2226 845ec3c4cb452fb2644082842160cbc3 560 SUPERFAMILY SSF56112 249 537 2.63E-27 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFE_2226 845ec3c4cb452fb2644082842160cbc3 560 Gene3D G3DSA:3.90.1200.10 356 529 2.6E-11 T 12-10-2018 AFE_2226 845ec3c4cb452fb2644082842160cbc3 560 Pfam PF01636 Phosphotransferase enzyme family 270 484 2.4E-14 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFE_1039 7dc305c2e99c1bd7a7c65cf6b69ab67b 353 TIGRFAM TIGR03115 cas7_csf2: CRISPR type IV/AFERR-associated protein Csf2 5 340 6.5E-159 T 12-10-2018 IPR017546 CRISPR type IV/AFERR-associated protein Csf2 AFE_2140 73632668b66220bf9b89745c020978ca 191 PIRSF PIRSF006806 1 186 1.3E-34 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFE_2140 73632668b66220bf9b89745c020978ca 191 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 1 183 8.5E-39 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFE_2140 73632668b66220bf9b89745c020978ca 191 SUPERFAMILY SSF100950 1 189 6.28E-52 T 12-10-2018 IPR037171 NagB/RpiA transferase-like AFE_2140 73632668b66220bf9b89745c020978ca 191 Gene3D G3DSA:3.40.50.10420 1 191 3.1E-53 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AFE_2140 73632668b66220bf9b89745c020978ca 191 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 1 183 1.9E-47 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFE_1292 fcc3d07340f5cdfca665ff2696e6045c 644 Gene3D G3DSA:3.40.50.410 473 639 1.5E-7 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_1292 fcc3d07340f5cdfca665ff2696e6045c 644 SUPERFAMILY SSF53300 479 612 1.35E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFE_1292 fcc3d07340f5cdfca665ff2696e6045c 644 Pfam PF06213 Cobalamin biosynthesis protein CobT 10 278 6.6E-11 T 12-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 AFE_2160 7daeffbbf57e223b0fe8349ccedff0fb 235 SUPERFAMILY SSF53335 40 216 1.61E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2160 7daeffbbf57e223b0fe8349ccedff0fb 235 Gene3D G3DSA:3.40.50.150 24 229 1.6E-37 T 12-10-2018 AFE_0498 f0347342d15785cdc21615baef4fbb16 145 Gene3D G3DSA:3.10.450.50 1 145 8.8E-46 T 12-10-2018 AFE_0498 f0347342d15785cdc21615baef4fbb16 145 Pfam PF07366 SnoaL-like polyketide cyclase 11 138 2.7E-28 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 AFE_0498 f0347342d15785cdc21615baef4fbb16 145 SUPERFAMILY SSF54427 5 139 8.05E-31 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFE_0356 d17275da2f3cc6a3137796c22a5db245 150 Gene3D G3DSA:2.70.40.10 1 149 2.8E-44 T 12-10-2018 IPR036157 dUTPase-like superfamily AFE_0356 d17275da2f3cc6a3137796c22a5db245 150 SUPERFAMILY SSF51283 3 149 1.44E-44 T 12-10-2018 IPR036157 dUTPase-like superfamily AFE_0356 d17275da2f3cc6a3137796c22a5db245 150 Pfam PF00692 dUTPase 16 148 2.2E-28 T 12-10-2018 IPR029054 dUTPase-like AFE_0356 d17275da2f3cc6a3137796c22a5db245 150 TIGRFAM TIGR00576 dut: dUTP diphosphatase 11 149 3.4E-40 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 AFE_0908 9c9196a29f845e95edfdbd7a3374a150 189 Pfam PF00156 Phosphoribosyl transferase domain 40 146 4.1E-7 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFE_0908 9c9196a29f845e95edfdbd7a3374a150 189 TIGRFAM TIGR01367 pyrE_Therm: orotate phosphoribosyltransferase 3 186 2.5E-58 T 12-10-2018 IPR006273 Orotate phosphoribosyltransferase, bacterial GO:0004588|GO:0019856 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFE_0908 9c9196a29f845e95edfdbd7a3374a150 189 Gene3D G3DSA:3.40.50.2020 1 188 2.5E-48 T 12-10-2018 AFE_0908 9c9196a29f845e95edfdbd7a3374a150 189 SUPERFAMILY SSF53271 3 185 6.96E-29 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like AFE_0908 9c9196a29f845e95edfdbd7a3374a150 189 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 189 23.725 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFE_2757 04052e3b51ae82f9572d0c2d7a367919 83 Gene3D G3DSA:3.30.70.20 2 81 1.1E-32 T 12-10-2018 AFE_2757 04052e3b51ae82f9572d0c2d7a367919 83 Pfam PF00037 4Fe-4S binding domain 6 25 6.9E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFE_2757 04052e3b51ae82f9572d0c2d7a367919 83 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFE_2757 04052e3b51ae82f9572d0c2d7a367919 83 SUPERFAMILY SSF54862 5 67 4.83E-19 T 12-10-2018 AFE_1233 8fa22832480eb498cf6a64900bd57931 151 Gene3D G3DSA:3.40.960.10 41 143 8.7E-15 T 12-10-2018 AFE_1233 8fa22832480eb498cf6a64900bd57931 151 Pfam PF04480 Protein of unknown function (DUF559) 66 139 1.6E-5 T 12-10-2018 IPR007569 Protein of unknown function DUF559 AFE_1233 8fa22832480eb498cf6a64900bd57931 151 SUPERFAMILY SSF52980 65 141 5.09E-6 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFE_2989 3e897c53a8ce445040c7f34a8df8fa81 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 244 325 2.5E-22 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFE_2989 3e897c53a8ce445040c7f34a8df8fa81 333 Gene3D G3DSA:3.40.50.300 15 329 4.6E-96 T 12-10-2018 AFE_2989 3e897c53a8ce445040c7f34a8df8fa81 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 309 2.3E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFE_2989 3e897c53a8ce445040c7f34a8df8fa81 333 SMART SM00382 44 243 1.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2989 3e897c53a8ce445040c7f34a8df8fa81 333 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2989 3e897c53a8ce445040c7f34a8df8fa81 333 SUPERFAMILY SSF52540 16 264 4.39E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2989 3e897c53a8ce445040c7f34a8df8fa81 333 Pfam PF00005 ABC transporter 36 193 1.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0852 35c8a451cfe05e06de5b935422aca279 100 Pfam PF06155 Protein of unknown function (DUF971) 17 95 5.5E-30 T 12-10-2018 IPR010376 Gamma-butyrobetaine hydroxylase-like, N-terminal Reactome: R-HSA-71262 AFE_0852 35c8a451cfe05e06de5b935422aca279 100 Gene3D G3DSA:3.30.2020.30 1 100 4.6E-40 T 12-10-2018 IPR038492 GBBH-like, N-terminal domain superfamily Reactome: R-HSA-71262 AFE_1782 0ee9d1c62303947b16a2923950773394 539 PIRSF PIRSF006060 452 536 3200.0 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_1782 0ee9d1c62303947b16a2923950773394 539 PIRSF PIRSF006060 6 459 3.8E-61 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_1782 0ee9d1c62303947b16a2923950773394 539 Gene3D G3DSA:1.20.1740.10 13 462 5.1E-57 T 12-10-2018 AFE_1782 0ee9d1c62303947b16a2923950773394 539 Pfam PF13520 Amino acid permease 19 429 1.9E-38 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_3163 b4e028a3f7d6430bf2beb2d017a1f964 106 SMART SM00830 19 98 4.6E-19 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFE_3163 b4e028a3f7d6430bf2beb2d017a1f964 106 Pfam PF01817 Chorismate mutase type II 19 95 3.9E-15 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFE_3163 b4e028a3f7d6430bf2beb2d017a1f964 106 Gene3D G3DSA:1.20.59.10 7 105 1.6E-33 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFE_3163 b4e028a3f7d6430bf2beb2d017a1f964 106 SUPERFAMILY SSF48600 8 98 2.75E-22 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFE_1978 4bfb0c8d01a862e0f1c49e3547b5b695 275 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 200 257 5.6E-8 T 12-10-2018 IPR006260 TonB/TolA, C-terminal AFE_1978 4bfb0c8d01a862e0f1c49e3547b5b695 275 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 200 262 1.1E-8 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 AFE_1978 4bfb0c8d01a862e0f1c49e3547b5b695 275 Gene3D G3DSA:3.30.1150.10 168 270 8.7E-10 T 12-10-2018 AFE_1978 4bfb0c8d01a862e0f1c49e3547b5b695 275 SUPERFAMILY SSF74653 166 265 6.02E-8 T 12-10-2018 AFE_2185 417dd602e63572d588c3bea982873ce5 147 Pfam PF12802 MarR family 32 91 6.7E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFE_2185 417dd602e63572d588c3bea982873ce5 147 SMART SM00347 27 128 1.6E-26 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFE_2185 417dd602e63572d588c3bea982873ce5 147 Gene3D G3DSA:1.10.10.10 2 145 9.5E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2185 417dd602e63572d588c3bea982873ce5 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 2.9E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFE_2185 417dd602e63572d588c3bea982873ce5 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 2.9E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFE_2185 417dd602e63572d588c3bea982873ce5 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 2.9E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFE_2185 417dd602e63572d588c3bea982873ce5 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 2.9E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFE_2185 417dd602e63572d588c3bea982873ce5 147 SUPERFAMILY SSF46785 4 143 2.45E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2323 cbff84df85a1370fde4880362187e015 296 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 18 293 7.6E-46 T 12-10-2018 IPR025859 P-aminobenzoate N-oxygenase AurF AFE_2323 cbff84df85a1370fde4880362187e015 296 SUPERFAMILY SSF47240 36 237 2.78E-5 T 12-10-2018 IPR009078 Ferritin-like superfamily AFE_2323 cbff84df85a1370fde4880362187e015 296 Gene3D G3DSA:1.10.620.20 19 295 3.3E-5 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 AFE_2879 3183ce7bc4443ff442994f2862cf0612 254 Pfam PF13672 Protein phosphatase 2C 12 233 1.5E-44 T 12-10-2018 AFE_2879 3183ce7bc4443ff442994f2862cf0612 254 SUPERFAMILY SSF81606 10 253 1.83E-13 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFE_2879 3183ce7bc4443ff442994f2862cf0612 254 Gene3D G3DSA:3.60.40.10 2 253 1.1E-11 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFE_0951 5aa714a416f98ec2de77a67be9d92eae 468 SUPERFAMILY SSF53720 4 452 1.83E-102 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFE_0951 5aa714a416f98ec2de77a67be9d92eae 468 Gene3D G3DSA:3.40.605.10 15 437 6.5E-130 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFE_0951 5aa714a416f98ec2de77a67be9d92eae 468 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 238 249 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFE_0951 5aa714a416f98ec2de77a67be9d92eae 468 PIRSF PIRSF036492 2 468 1.8E-135 T 12-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 AFE_0951 5aa714a416f98ec2de77a67be9d92eae 468 Pfam PF00171 Aldehyde dehydrogenase family 4 434 1.6E-72 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFE_0951 5aa714a416f98ec2de77a67be9d92eae 468 Gene3D G3DSA:3.40.309.10 214 417 6.5E-130 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFE_0232 c80d95f24fc2611dde31904d38952c03 417 Pfam PF04932 O-Antigen ligase 199 342 6.0E-8 T 12-10-2018 IPR007016 O-antigen ligase-related AFE_0535 aa18b13157edb491b2544b85eae7a9bb 272 Pfam PF02219 Methylenetetrahydrofolate reductase 3 271 1.8E-85 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 AFE_0535 aa18b13157edb491b2544b85eae7a9bb 272 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 4 270 2.3E-96 T 12-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 AFE_0535 aa18b13157edb491b2544b85eae7a9bb 272 Gene3D G3DSA:3.20.20.220 1 272 5.3E-97 T 12-10-2018 AFE_0535 aa18b13157edb491b2544b85eae7a9bb 272 SUPERFAMILY SSF51730 3 271 2.16E-90 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like AFE_0795 6e81212967dee121b577e17f3edce62b 271 Gene3D G3DSA:3.40.47.10 13 174 1.2E-7 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_0795 6e81212967dee121b577e17f3edce62b 271 SUPERFAMILY SSF53901 41 167 2.09E-10 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 AFE_0795 6e81212967dee121b577e17f3edce62b 271 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 35 199 9.8E-29 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal AFE_0159 30fb76026d493006ff8729717824c96f 260 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 19 259 1.8E-83 T 12-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria AFE_0159 30fb76026d493006ff8729717824c96f 260 Pfam PF02405 Permease MlaE 46 256 1.0E-73 T 12-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 AFE_0302 9ed55de1ff380cc9455e3c57f893e34b 93 Pfam PF11154 Protein of unknown function (DUF2934) 53 89 3.5E-12 T 12-10-2018 IPR021327 Protein of unknown function DUF2934 AFE_1780 b15e9f85def050886b6bc7c58c2a8d2b 139 Gene3D G3DSA:3.40.50.1010 1 138 1.4E-37 T 12-10-2018 AFE_1780 b15e9f85def050886b6bc7c58c2a8d2b 139 Pfam PF01850 PIN domain 2 128 1.1E-18 T 12-10-2018 IPR002716 PIN domain AFE_1780 b15e9f85def050886b6bc7c58c2a8d2b 139 SUPERFAMILY SSF88723 1 136 6.17E-30 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_1780 b15e9f85def050886b6bc7c58c2a8d2b 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 135 12.718 T 12-10-2018 IPR022907 VapC family GO:0004540 AFE_2378 e2a2cb194775c2c503c3a87724c3d5e1 383 Pfam PF01420 Type I restriction modification DNA specificity domain 198 364 2.8E-24 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AFE_2378 e2a2cb194775c2c503c3a87724c3d5e1 383 SUPERFAMILY SSF116734 12 180 1.05E-22 T 12-10-2018 AFE_2378 e2a2cb194775c2c503c3a87724c3d5e1 383 Gene3D G3DSA:3.90.220.20 200 333 1.6E-50 T 12-10-2018 AFE_2378 e2a2cb194775c2c503c3a87724c3d5e1 383 Gene3D G3DSA:1.10.287.1120 136 375 1.6E-50 T 12-10-2018 AFE_2378 e2a2cb194775c2c503c3a87724c3d5e1 383 SUPERFAMILY SSF116734 195 376 3.11E-37 T 12-10-2018 AFE_2378 e2a2cb194775c2c503c3a87724c3d5e1 383 Gene3D G3DSA:3.90.220.20 47 135 1.6E-50 T 12-10-2018 AFE_1699 988ddcb3e9cea63a41d23eed45fdfa14 834 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 247 718 1.5E-103 T 12-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 AFE_1699 988ddcb3e9cea63a41d23eed45fdfa14 834 Gene3D G3DSA:3.40.50.300 442 715 1.2E-45 T 12-10-2018 AFE_1699 988ddcb3e9cea63a41d23eed45fdfa14 834 SUPERFAMILY SSF52540 266 715 4.94E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2571 848f886cecdf890f9129f7be2fe08904 266 Pfam PF02698 DUF218 domain 86 251 8.8E-26 T 12-10-2018 IPR003848 Domain of unknown function DUF218 AFE_0258 4f4ace2ca3b904ceca48833abe4b4b77 188 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 79 180 1.8E-14 T 12-10-2018 IPR018550 Lipid A 3-O-deacylase-related AFE_0258 4f4ace2ca3b904ceca48833abe4b4b77 188 Gene3D G3DSA:2.40.160.20 116 182 9.0E-9 T 12-10-2018 AFE_0923 30b8a032685036a90ceb90ea83c1aff1 221 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 25 212 2.0E-23 T 12-10-2018 AFE_0923 30b8a032685036a90ceb90ea83c1aff1 221 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 8 214 29.351 T 12-10-2018 IPR007451 High frequency lysogenization protein HflD AFE_0923 30b8a032685036a90ceb90ea83c1aff1 221 Gene3D G3DSA:1.10.3890.10 8 218 6.7E-56 T 12-10-2018 IPR035932 HflD-like superfamily AFE_0923 30b8a032685036a90ceb90ea83c1aff1 221 SUPERFAMILY SSF101322 11 214 7.32E-48 T 12-10-2018 IPR035932 HflD-like superfamily AFE_0923 30b8a032685036a90ceb90ea83c1aff1 221 Pfam PF04356 Protein of unknown function (DUF489) 14 207 7.2E-52 T 12-10-2018 IPR007451 High frequency lysogenization protein HflD AFE_0436 95316afb29db39e1ff18b95298a2571e 206 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 195 2.9E-38 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFE_0436 95316afb29db39e1ff18b95298a2571e 206 Gene3D G3DSA:3.40.225.10 2 205 1.6E-50 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFE_0436 95316afb29db39e1ff18b95298a2571e 206 SMART SM01007 7 197 7.8E-43 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFE_0436 95316afb29db39e1ff18b95298a2571e 206 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 9 201 5.3E-63 T 12-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 AFE_0436 95316afb29db39e1ff18b95298a2571e 206 SUPERFAMILY SSF53639 3 201 3.73E-42 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFE_0436 95316afb29db39e1ff18b95298a2571e 206 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 205 87.13 T 12-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 AFE_3235 7834f227a6dfb02ad098e8f6c34ee85d 258 Pfam PF01061 ABC-2 type transporter 14 221 2.0E-24 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFE_3235 7834f227a6dfb02ad098e8f6c34ee85d 258 TIGRFAM TIGR01291 nodJ: ABC-2 type transporter, NodJ family 13 256 1.5E-68 T 12-10-2018 IPR005981 ABC-2 type transporter, NodJ GO:0005215|GO:0009877|GO:0015772|GO:0016020 AFE_3235 7834f227a6dfb02ad098e8f6c34ee85d 258 PIRSF PIRSF006648 2 257 4.9E-25 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_3235 7834f227a6dfb02ad098e8f6c34ee85d 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 180 199 3.3E-40 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_3235 7834f227a6dfb02ad098e8f6c34ee85d 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 143 167 3.3E-40 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_3235 7834f227a6dfb02ad098e8f6c34ee85d 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 61 83 3.3E-40 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_3235 7834f227a6dfb02ad098e8f6c34ee85d 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 31 52 3.3E-40 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_3235 7834f227a6dfb02ad098e8f6c34ee85d 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 106 131 3.3E-40 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_3235 7834f227a6dfb02ad098e8f6c34ee85d 258 PRINTS PR00164 ABC-2 type transport system membrane protein signature 200 219 3.3E-40 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_0990 c91bd2346aee29aa7d6cbbb48463df72 130 SUPERFAMILY SSF81301 4 116 1.37E-6 T 12-10-2018 AFE_3157 8611bde2c4fbdc9abc94dac05258302a 97 Pfam PF13592 Winged helix-turn helix 1 40 2.7E-10 T 12-10-2018 IPR025959 Winged helix-turn helix domain AFE_0193 2420f8ccabf74050623e000aa98466a7 210 Pfam PF11906 Protein of unknown function (DUF3426) 63 205 7.5E-25 T 12-10-2018 IPR021834 Protein of unknown function DUF3426 AFE_0193 2420f8ccabf74050623e000aa98466a7 210 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 1 36 1.1E-6 T 12-10-2018 IPR011723 Zinc finger/thioredoxin putative AFE_0193 2420f8ccabf74050623e000aa98466a7 210 Pfam PF13717 zinc-ribbon domain 1 35 1.7E-9 T 12-10-2018 IPR011723 Zinc finger/thioredoxin putative AFE_2999 5b80224b1d9f4c6cbbf97616b6a9f5af 210 Pfam PF01914 MarC family integral membrane protein 7 204 1.9E-44 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFE_2999 5b80224b1d9f4c6cbbf97616b6a9f5af 210 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 202 1.3E-44 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFE_0489 93c7a7c0d4afa9e3b613aab289cda089 332 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 40 320 4.5E-57 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 AFE_0489 93c7a7c0d4afa9e3b613aab289cda089 332 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 6 332 31.945 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 AFE_0489 93c7a7c0d4afa9e3b613aab289cda089 332 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 18 326 6.6E-83 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 AFE_0489 93c7a7c0d4afa9e3b613aab289cda089 332 SUPERFAMILY SSF52540 49 161 2.94E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0065 bc56f90142aa93bf9d7d5ca5d35fe23a 136 TIGRFAM TIGR02801 tolR: protein TolR 7 131 7.1E-41 T 12-10-2018 IPR014168 Tol-Pal system protein TolR GO:0015031|GO:0016021 AFE_0065 bc56f90142aa93bf9d7d5ca5d35fe23a 136 Pfam PF02472 Biopolymer transport protein ExbD/TolR 4 134 5.4E-24 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 AFE_0065 bc56f90142aa93bf9d7d5ca5d35fe23a 136 Gene3D G3DSA:3.30.420.270 55 129 1.5E-13 T 12-10-2018 AFE_0044 a152a5e44b7faca8cd25a0049c090810 356 PIRSF PIRSF037390 2 356 3.8E-111 T 12-10-2018 IPR017192 Thiosulphate:quinone oxidoreductase, fused subunit DoxA/ DoxD AFE_0044 a152a5e44b7faca8cd25a0049c090810 356 Pfam PF04173 TQO small subunit DoxD 22 172 5.8E-26 T 12-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 AFE_0044 a152a5e44b7faca8cd25a0049c090810 356 Pfam PF07680 TQO small subunit DoxA 233 351 3.4E-13 T 12-10-2018 IPR011636 Thiosulphate:quinone oxidoreductase small subunit DoxA KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 AFE_0741 c61ff66f9e2e8ceab737d385fd6c8dd7 177 Pfam PF14437 MafB19-like deaminase 12 135 6.8E-24 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 AFE_0741 c61ff66f9e2e8ceab737d385fd6c8dd7 177 SUPERFAMILY SSF53927 6 158 5.02E-51 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFE_0741 c61ff66f9e2e8ceab737d385fd6c8dd7 177 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 61 98 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFE_0741 c61ff66f9e2e8ceab737d385fd6c8dd7 177 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 15 157 43.779 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 AFE_0741 c61ff66f9e2e8ceab737d385fd6c8dd7 177 Gene3D G3DSA:3.40.140.10 5 166 1.0E-54 T 12-10-2018 AFE_0336 cc4e3bac4e90ff4e500630a59e04ae8d 91 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 24.693 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0336 cc4e3bac4e90ff4e500630a59e04ae8d 91 Gene3D G3DSA:2.40.50.140 4 86 1.2E-36 T 12-10-2018 AFE_0336 cc4e3bac4e90ff4e500630a59e04ae8d 91 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 8 78 2.7E-37 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0336 cc4e3bac4e90ff4e500630a59e04ae8d 91 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 6.0E-23 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0336 cc4e3bac4e90ff4e500630a59e04ae8d 91 SUPERFAMILY SSF50249 8 83 4.11E-33 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFE_0336 cc4e3bac4e90ff4e500630a59e04ae8d 91 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0336 cc4e3bac4e90ff4e500630a59e04ae8d 91 Pfam PF00366 Ribosomal protein S17 12 78 9.3E-35 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0336 cc4e3bac4e90ff4e500630a59e04ae8d 91 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 8.5E-15 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0336 cc4e3bac4e90ff4e500630a59e04ae8d 91 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 8.5E-15 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0336 cc4e3bac4e90ff4e500630a59e04ae8d 91 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 8.5E-15 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 SUPERFAMILY SSF117892 51 185 7.72E-37 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 SMART SM00244 20 178 1.6E-54 T 12-10-2018 IPR001107 Band 7 domain AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 Gene3D G3DSA:3.30.479.30 48 180 8.2E-37 T 12-10-2018 AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 Pfam PF01145 SPFH domain / Band 7 family 24 194 2.2E-28 T 12-10-2018 IPR001107 Band 7 domain AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 PRINTS PR00721 Stomatin signature 110 127 6.6E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 PRINTS PR00721 Stomatin signature 173 194 6.6E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 PRINTS PR00721 Stomatin signature 27 49 6.6E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 PRINTS PR00721 Stomatin signature 154 172 6.6E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 PRINTS PR00721 Stomatin signature 130 153 6.6E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 PRINTS PR00721 Stomatin signature 75 96 6.6E-27 T 12-10-2018 IPR001972 Stomatin family GO:0016020 AFE_2834 e7ff0234cb31969b478b2d9504d88b6b 312 Pfam PF16200 C-terminal region of band_7 244 303 7.1E-18 T 12-10-2018 IPR032435 Band 7, C-terminal extension Reactome: R-HSA-8949664 AFE_0340 e5e5acfcf705263bdbc45218bd6414cf 61 SUPERFAMILY SSF57716 4 61 2.35E-20 T 12-10-2018 AFE_0340 e5e5acfcf705263bdbc45218bd6414cf 61 Gene3D G3DSA:4.10.830.10 1 61 9.5E-29 T 12-10-2018 AFE_0340 e5e5acfcf705263bdbc45218bd6414cf 61 Pfam PF00253 Ribosomal protein S14p/S29e 11 60 2.7E-23 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_0340 e5e5acfcf705263bdbc45218bd6414cf 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 12-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFE_0340 e5e5acfcf705263bdbc45218bd6414cf 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 24.519 T 12-10-2018 IPR023053 Ribosomal protein S14, type Z AFE_3301 d2b22f6803be28e1ac24b9683541ddf6 91 Gene3D G3DSA:1.10.150.280 13 80 9.3E-15 T 12-10-2018 AFE_3301 d2b22f6803be28e1ac24b9683541ddf6 91 SUPERFAMILY SSF47781 14 78 2.45E-18 T 12-10-2018 IPR010994 RuvA domain 2-like AFE_3301 d2b22f6803be28e1ac24b9683541ddf6 91 Pfam PF12836 Helix-hairpin-helix motif 17 72 4.3E-14 T 12-10-2018 AFE_0999 bc5c041e88a500e684e8d384cecebe7d 69 SUPERFAMILY SSF47413 1 58 7.69E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_0999 bc5c041e88a500e684e8d384cecebe7d 69 Gene3D G3DSA:1.10.260.40 3 68 4.4E-19 T 12-10-2018 AFE_0999 bc5c041e88a500e684e8d384cecebe7d 69 Pfam PF14549 DNA-binding transcriptional regulator Cro 2 62 1.7E-21 T 12-10-2018 AFE_2677 2f235d59178a2ca0aaef2afa09c09215 189 Gene3D G3DSA:3.40.50.2000 5 185 3.0E-23 T 12-10-2018 AFE_2480 b72cd58800b1a218a445e6eeb67ba0ee 144 ProDom PD007347 MERC PLASMID MEMBRANE INNER UPTAKE MERCURY HGII RESISTANCE PRECURSOR TRANSMEMBRANE 23 140 2.0E-55 T 12-10-2018 IPR004891 Mercury transport protein MerC GO:0015097|GO:0015694|GO:0016020 AFE_2480 b72cd58800b1a218a445e6eeb67ba0ee 144 Pfam PF03203 MerC mercury resistance protein 9 124 6.0E-20 T 12-10-2018 IPR004891 Mercury transport protein MerC GO:0015097|GO:0015694|GO:0016020 AFE_0841 1947943c70a9d0912b5f8c5b700ea70a 973 Gene3D G3DSA:3.40.50.300 259 442 8.0E-43 T 12-10-2018 AFE_0841 1947943c70a9d0912b5f8c5b700ea70a 973 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 35 669 6.1E-141 T 12-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 AFE_0841 1947943c70a9d0912b5f8c5b700ea70a 973 SMART SM00487 256 445 1.8E-13 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFE_0841 1947943c70a9d0912b5f8c5b700ea70a 973 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 5 198 4.0E-22 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 AFE_0841 1947943c70a9d0912b5f8c5b700ea70a 973 Pfam PF04851 Type III restriction enzyme, res subunit 258 416 8.7E-19 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFE_0841 1947943c70a9d0912b5f8c5b700ea70a 973 Gene3D G3DSA:3.40.50.300 443 681 8.1E-33 T 12-10-2018 AFE_0841 1947943c70a9d0912b5f8c5b700ea70a 973 SUPERFAMILY SSF52540 230 424 8.12E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0841 1947943c70a9d0912b5f8c5b700ea70a 973 Gene3D G3DSA:3.90.1570.50 90 255 6.4E-20 T 12-10-2018 AFE_2963 d9f04320447cab81aef5b0b53751f456 217 SUPERFAMILY SSF52540 2 213 9.85E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2963 d9f04320447cab81aef5b0b53751f456 217 SMART SM00382 32 200 8.7E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_2963 d9f04320447cab81aef5b0b53751f456 217 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_2963 d9f04320447cab81aef5b0b53751f456 217 Gene3D G3DSA:3.40.50.300 1 216 2.8E-33 T 12-10-2018 AFE_2963 d9f04320447cab81aef5b0b53751f456 217 Pfam PF00005 ABC transporter 23 152 4.3E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_0274 2ea5ee5f81d702d2fa1d15d92c3809c6 178 Pfam PF02600 Disulfide bond formation protein DsbB 18 167 1.3E-22 T 12-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 AFE_0274 2ea5ee5f81d702d2fa1d15d92c3809c6 178 SUPERFAMILY SSF158442 20 168 1.44E-20 T 12-10-2018 IPR023380 DsbB-like superfamily AFE_0274 2ea5ee5f81d702d2fa1d15d92c3809c6 178 Gene3D G3DSA:1.20.1550.10 8 177 2.2E-21 T 12-10-2018 IPR023380 DsbB-like superfamily AFE_1097 c9543459d128b2ccf798cbab5e4f2be5 1019 Gene3D G3DSA:2.60.120.260 434 596 6.3E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFE_1097 c9543459d128b2ccf798cbab5e4f2be5 1019 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation 860 939 9.4E-20 T 12-10-2018 IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN AFE_1097 c9543459d128b2ccf798cbab5e4f2be5 1019 Pfam PF06986 Type-1V conjugative transfer system mating pair stabilisation 593 683 1.2E-6 T 12-10-2018 IPR014121 Type-F conjugative transfer system mating-pair stabilisation protein TraN AFE_3245 d5491176c18ce56d0dc126cddf1dd2f1 505 SUPERFAMILY SSF56322 15 488 6.8E-162 T 12-10-2018 IPR005801 ADC synthase GO:0009058 AFE_3245 d5491176c18ce56d0dc126cddf1dd2f1 505 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 27 486 4.9E-174 T 12-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_3245 d5491176c18ce56d0dc126cddf1dd2f1 505 Gene3D G3DSA:3.60.120.10 2 495 2.9E-185 T 12-10-2018 IPR005801 ADC synthase GO:0009058 AFE_3245 d5491176c18ce56d0dc126cddf1dd2f1 505 PRINTS PR00095 Anthranilate synthase component I signature 340 353 3.1E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_3245 d5491176c18ce56d0dc126cddf1dd2f1 505 PRINTS PR00095 Anthranilate synthase component I signature 420 434 3.1E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_3245 d5491176c18ce56d0dc126cddf1dd2f1 505 PRINTS PR00095 Anthranilate synthase component I signature 326 339 3.1E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_3245 d5491176c18ce56d0dc126cddf1dd2f1 505 PRINTS PR00095 Anthranilate synthase component I signature 435 449 3.1E-24 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_3245 d5491176c18ce56d0dc126cddf1dd2f1 505 Pfam PF00425 chorismate binding enzyme 224 478 6.9E-102 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFE_3245 d5491176c18ce56d0dc126cddf1dd2f1 505 Pfam PF04715 Anthranilate synthase component I, N terminal region 27 171 1.1E-31 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFE_3173 2d29586867239a19c8b336a816e59fd8 141 Pfam PF10130 PIN domain 7 138 7.5E-45 T 12-10-2018 IPR002716 PIN domain AFE_3173 2d29586867239a19c8b336a816e59fd8 141 SUPERFAMILY SSF88723 1 131 1.15E-8 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_1615 c85fc5e6aa3787c0cb7e8fe89cae2253 1449 Pfam PF12083 Domain of unknown function (DUF3560) 991 1111 8.4E-42 T 12-10-2018 IPR021944 Protein of unknown function DUF3560 AFE_1615 c85fc5e6aa3787c0cb7e8fe89cae2253 1449 Pfam PF08401 Domain of unknown function (DUF1738) 21 141 1.1E-30 T 12-10-2018 IPR013610 Domain of unknown function DUF1738 AFE_2522 2314e1855582d5d9c1a789de8e0ed7f6 418 Pfam PF04966 Carbohydrate-selective porin, OprB family 93 417 8.6E-28 T 12-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 AFE_2522 2314e1855582d5d9c1a789de8e0ed7f6 418 Gene3D G3DSA:2.40.160.180 55 417 1.3E-59 T 12-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily AFE_1941 366074084de0125d978a64906a8fe39b 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 285 6.9E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFE_1941 366074084de0125d978a64906a8fe39b 303 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 30 291 8.4E-58 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 AFE_1941 366074084de0125d978a64906a8fe39b 303 SUPERFAMILY SSF161098 27 289 3.18E-31 T 12-10-2018 IPR035906 MetI-like superfamily AFE_1941 366074084de0125d978a64906a8fe39b 303 Gene3D G3DSA:1.10.3720.10 71 292 9.9E-26 T 12-10-2018 IPR035906 MetI-like superfamily AFE_1523 d0fa4f2cc200a12ad8b8679d0a9ac7cc 128 Gene3D G3DSA:3.40.50.2300 8 128 8.3E-11 T 12-10-2018 AFE_1523 d0fa4f2cc200a12ad8b8679d0a9ac7cc 128 SUPERFAMILY SSF52172 13 127 3.27E-11 T 12-10-2018 IPR011006 CheY-like superfamily AFE_2116 b670b85a123c9ac4fb40eaad8e2ff49d 280 SUPERFAMILY SSF47240 21 198 3.16E-18 T 12-10-2018 IPR009078 Ferritin-like superfamily AFE_0478 b24f0fd682aded4d565b4952fefe0748 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 130 12.612 T 12-10-2018 IPR022907 VapC family GO:0004540 AFE_0478 b24f0fd682aded4d565b4952fefe0748 134 SUPERFAMILY SSF88723 2 132 1.35E-35 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_0478 b24f0fd682aded4d565b4952fefe0748 134 Gene3D G3DSA:3.40.50.1010 1 132 1.3E-41 T 12-10-2018 AFE_0478 b24f0fd682aded4d565b4952fefe0748 134 Pfam PF01850 PIN domain 3 125 6.4E-19 T 12-10-2018 IPR002716 PIN domain AFE_3042 bf9c30a898e257b6fcefdaf8ef0823de 359 Pfam PF00155 Aminotransferase class I and II 32 353 1.1E-38 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFE_3042 bf9c30a898e257b6fcefdaf8ef0823de 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 19 357 1.1E-87 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFE_3042 bf9c30a898e257b6fcefdaf8ef0823de 359 SUPERFAMILY SSF53383 19 358 6.68E-67 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFE_3042 bf9c30a898e257b6fcefdaf8ef0823de 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 13 359 52.999 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFE_3042 bf9c30a898e257b6fcefdaf8ef0823de 359 Gene3D G3DSA:3.40.640.10 55 268 3.7E-105 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFE_3042 bf9c30a898e257b6fcefdaf8ef0823de 359 Gene3D G3DSA:3.90.1150.10 21 353 3.7E-105 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFE_0523 ef29d258a4c288631f98e9c54e16bc66 203 Pfam PF01965 DJ-1/PfpI family 6 167 1.7E-45 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AFE_0523 ef29d258a4c288631f98e9c54e16bc66 203 Gene3D G3DSA:3.40.50.880 3 185 4.5E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_0523 ef29d258a4c288631f98e9c54e16bc66 203 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 6 179 1.1E-51 T 12-10-2018 IPR006287 Protein/nucleic acid deglycase DJ-1 Reactome: R-HSA-3899300 AFE_0523 ef29d258a4c288631f98e9c54e16bc66 203 SUPERFAMILY SSF52317 6 181 1.39E-50 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_2974 01b2beda12c58b975fe7f9b2e2efe3a3 585 Gene3D G3DSA:3.20.20.490 329 583 1.1E-49 T 12-10-2018 IPR038410 GxGYxYP putative glycoside hydrolase, C-terminal domain superfamily AFE_2974 01b2beda12c58b975fe7f9b2e2efe3a3 585 Pfam PF16216 GxGYxY sequence motif in domain of unknown function N-terminal 97 325 2.7E-53 T 12-10-2018 IPR032626 GxGYxYP putative glycoside hydrolase, N-terminal AFE_2974 01b2beda12c58b975fe7f9b2e2efe3a3 585 Pfam PF14323 GxGYxYP putative glycoside hydrolase C-terminal domain 345 579 4.7E-60 T 12-10-2018 IPR025832 GxGYxYP putative glycoside hydrolase, C-terminal AFE_2921 ebd23264ba74158513cf0b1c67299a01 361 SUPERFAMILY SSF50685 100 181 8.02E-11 T 12-10-2018 IPR036908 RlpA-like domain superfamily AFE_2921 ebd23264ba74158513cf0b1c67299a01 361 Gene3D G3DSA:2.40.40.10 87 180 5.2E-32 T 12-10-2018 IPR036908 RlpA-like domain superfamily AFE_2921 ebd23264ba74158513cf0b1c67299a01 361 Pfam PF03330 Lytic transglycolase 88 176 2.3E-22 T 12-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain AFE_2921 ebd23264ba74158513cf0b1c67299a01 361 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 90 183 8.6E-33 T 12-10-2018 IPR012997 Rare lipoprotein A AFE_2921 ebd23264ba74158513cf0b1c67299a01 361 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 19 180 21.359 T 12-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 AFE_1360 fed0c69f51022db59b97510f27316b99 146 SUPERFAMILY SSF81593 8 122 4.32E-24 T 12-10-2018 AFE_1360 fed0c69f51022db59b97510f27316b99 146 Gene3D G3DSA:1.20.120.330 4 129 1.7E-24 T 12-10-2018 AFE_1360 fed0c69f51022db59b97510f27316b99 146 SMART SM00748 14 123 1.4E-15 T 12-10-2018 IPR007842 HEPN domain AFE_1360 fed0c69f51022db59b97510f27316b99 146 Pfam PF05168 HEPN domain 11 122 3.1E-20 T 12-10-2018 IPR007842 HEPN domain AFE_1364 fed0c69f51022db59b97510f27316b99 146 SUPERFAMILY SSF81593 8 122 4.32E-24 T 12-10-2018 AFE_1364 fed0c69f51022db59b97510f27316b99 146 Gene3D G3DSA:1.20.120.330 4 129 1.7E-24 T 12-10-2018 AFE_1364 fed0c69f51022db59b97510f27316b99 146 SMART SM00748 14 123 1.4E-15 T 12-10-2018 IPR007842 HEPN domain AFE_1364 fed0c69f51022db59b97510f27316b99 146 Pfam PF05168 HEPN domain 11 122 3.1E-20 T 12-10-2018 IPR007842 HEPN domain AFE_3034 8be36f846674ddf718dead3e3c5d5f6e 701 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 3 681 17.354 T 12-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 AFE_3034 8be36f846674ddf718dead3e3c5d5f6e 701 Pfam PF03968 OstA-like protein 36 155 7.6E-8 T 12-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal AFE_3034 8be36f846674ddf718dead3e3c5d5f6e 701 Pfam PF04453 Organic solvent tolerance protein 259 621 1.8E-57 T 12-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 AFE_0970 41582206139f0ef6e25eca160ee766be 166 Pfam PF07963 Prokaryotic N-terminal methylation motif 17 40 1.6E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFE_0970 41582206139f0ef6e25eca160ee766be 166 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 18 38 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFE_0970 41582206139f0ef6e25eca160ee766be 166 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 18 39 9.1E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFE_1929 8c8832812157aa851906479b995424d4 141 SMART SM00562 3 140 2.8E-81 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFE_1929 8c8832812157aa851906479b995424d4 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 7.6E-38 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFE_1929 8c8832812157aa851906479b995424d4 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 7.6E-38 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFE_1929 8c8832812157aa851906479b995424d4 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 7.6E-38 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFE_1929 8c8832812157aa851906479b995424d4 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 7.6E-38 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFE_1929 8c8832812157aa851906479b995424d4 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 7.6E-38 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFE_1929 8c8832812157aa851906479b995424d4 141 Pfam PF00334 Nucleoside diphosphate kinase 4 138 1.9E-53 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFE_1929 8c8832812157aa851906479b995424d4 141 Gene3D G3DSA:3.30.70.141 1 141 2.6E-56 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFE_1929 8c8832812157aa851906479b995424d4 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.124 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFE_1929 8c8832812157aa851906479b995424d4 141 SUPERFAMILY SSF54919 1 139 1.14E-55 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFE_1779 d30e5a1d66cc1bac452be4a9e1fafe19 84 SUPERFAMILY SSF47598 2 69 1.14E-20 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFE_1779 d30e5a1d66cc1bac452be4a9e1fafe19 84 Gene3D G3DSA:1.10.1220.10 10 59 8.9E-23 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFE_1080 4c600bf765274a243ed3a17b514ba021 390 Pfam PF06586 TraK protein 169 374 2.0E-17 T 12-10-2018 IPR010563 Pilus assembly TraK AFE_2137 3dcba77d43ffde4774abbe61b75e4582 181 Pfam PF00857 Isochorismatase family 9 157 2.2E-28 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 AFE_2137 3dcba77d43ffde4774abbe61b75e4582 181 SUPERFAMILY SSF52499 2 176 1.83E-39 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFE_2137 3dcba77d43ffde4774abbe61b75e4582 181 Gene3D G3DSA:3.40.50.850 1 181 1.1E-45 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AFE_0835 151851b184613a2d46bafaca77f02187 414 Pfam PF00589 Phage integrase family 233 398 8.2E-22 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_0835 151851b184613a2d46bafaca77f02187 414 Gene3D G3DSA:1.10.443.10 231 406 2.1E-32 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_0835 151851b184613a2d46bafaca77f02187 414 Gene3D G3DSA:1.10.150.130 117 223 5.5E-8 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFE_0835 151851b184613a2d46bafaca77f02187 414 SUPERFAMILY SSF56349 126 406 1.53E-38 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_0835 151851b184613a2d46bafaca77f02187 414 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 125 204 8.2E-7 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFE_2397 151851b184613a2d46bafaca77f02187 414 Pfam PF00589 Phage integrase family 233 398 8.2E-22 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_2397 151851b184613a2d46bafaca77f02187 414 Gene3D G3DSA:1.10.443.10 231 406 2.1E-32 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_2397 151851b184613a2d46bafaca77f02187 414 Gene3D G3DSA:1.10.150.130 117 223 5.5E-8 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFE_2397 151851b184613a2d46bafaca77f02187 414 SUPERFAMILY SSF56349 126 406 1.53E-38 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_2397 151851b184613a2d46bafaca77f02187 414 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 125 204 8.2E-7 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFE_0507 151851b184613a2d46bafaca77f02187 414 Pfam PF00589 Phage integrase family 233 398 8.2E-22 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFE_0507 151851b184613a2d46bafaca77f02187 414 Gene3D G3DSA:1.10.443.10 231 406 2.1E-32 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFE_0507 151851b184613a2d46bafaca77f02187 414 Gene3D G3DSA:1.10.150.130 117 223 5.5E-8 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal AFE_0507 151851b184613a2d46bafaca77f02187 414 SUPERFAMILY SSF56349 126 406 1.53E-38 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFE_0507 151851b184613a2d46bafaca77f02187 414 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 125 204 8.2E-7 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFE_1419 e50f4ecdada1e2e861d683ab05a6d652 109 SUPERFAMILY SSF46955 44 100 2.56E-7 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily AFE_2745 ced97b76643885e4cd6afec9120ea272 227 Pfam PF04340 Protein of unknown function, DUF484 10 222 3.5E-29 T 12-10-2018 IPR007435 Protein of unknown function DUF484 AFE_2745 ced97b76643885e4cd6afec9120ea272 227 Gene3D G3DSA:3.30.450.40 44 225 2.5E-30 T 12-10-2018 IPR029016 GAF-like domain superfamily AFE_2549 18dadc44a7838ece7bb1654894aec45d 148 SUPERFAMILY SSF51230 16 112 7.32E-18 T 12-10-2018 IPR011053 Single hybrid motif AFE_2549 18dadc44a7838ece7bb1654894aec45d 148 Gene3D G3DSA:2.40.50.100 6 127 7.2E-23 T 12-10-2018 AFE_2549 18dadc44a7838ece7bb1654894aec45d 148 Pfam PF01597 Glycine cleavage H-protein 12 124 5.6E-28 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate AFE_0040 d13d1125cc4ecdd19342615eebdaee2b 540 Gene3D G3DSA:1.20.1720.10 23 231 9.4E-20 T 12-10-2018 AFE_0040 d13d1125cc4ecdd19342615eebdaee2b 540 Pfam PF07690 Major Facilitator Superfamily 30 418 6.2E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_0040 d13d1125cc4ecdd19342615eebdaee2b 540 SUPERFAMILY SSF103473 11 507 4.71E-35 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_0040 d13d1125cc4ecdd19342615eebdaee2b 540 Gene3D G3DSA:1.20.1250.20 280 507 7.8E-6 T 12-10-2018 AFE_2669 7a785cbb6f98607e24882902006c6151 51 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 12-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_2669 7a785cbb6f98607e24882902006c6151 51 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 15.717 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2669 7a785cbb6f98607e24882902006c6151 51 SUPERFAMILY SSF57829 1 49 3.36E-19 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFE_2669 7a785cbb6f98607e24882902006c6151 51 Pfam PF00471 Ribosomal protein L33 4 49 4.6E-19 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2669 7a785cbb6f98607e24882902006c6151 51 Gene3D G3DSA:2.20.28.120 1 51 1.4E-27 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_2669 7a785cbb6f98607e24882902006c6151 51 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 51 2.8E-24 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0725 378b5d186f0575a627c0450515ae9e1e 69 Pfam PF04324 BFD-like [2Fe-2S] binding domain 14 61 1.1E-5 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain AFE_2588 c0292f8039ad63425868269bdd3bb37e 233 Hamap MF_02089 Epoxyqueuosine reductase QueH [queH]. 18 194 33.737 T 12-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 AFE_2588 c0292f8039ad63425868269bdd3bb37e 233 Pfam PF02677 Uncharacterized BCR, COG1636 18 192 8.2E-64 T 12-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 AFE_2588 c0292f8039ad63425868269bdd3bb37e 233 SUPERFAMILY SSF52402 62 125 5.8E-5 T 12-10-2018 AFE_0848 bcf6607f1568684ebe45ae904d03e678 281 Gene3D G3DSA:3.20.20.70 3 274 8.8E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_0848 bcf6607f1568684ebe45ae904d03e678 281 Pfam PF00793 DAHP synthetase I family 8 267 8.0E-69 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFE_0848 bcf6607f1568684ebe45ae904d03e678 281 SUPERFAMILY SSF51569 3 270 5.31E-108 T 12-10-2018 AFE_0848 bcf6607f1568684ebe45ae904d03e678 281 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 270 53.223 T 12-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFE_0848 bcf6607f1568684ebe45ae904d03e678 281 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 268 1.2E-126 T 12-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFE_0702 af49dfb53cfa21c7315c91342d721a91 532 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 42 67 - T 12-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AFE_0702 af49dfb53cfa21c7315c91342d721a91 532 SUPERFAMILY SSF56762 7 516 2.35E-111 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_0702 af49dfb53cfa21c7315c91342d721a91 532 Pfam PF00374 Nickel-dependent hydrogenase 42 121 9.1E-16 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AFE_0702 af49dfb53cfa21c7315c91342d721a91 532 Pfam PF00374 Nickel-dependent hydrogenase 153 516 7.2E-56 T 12-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AFE_2273 164839d046899967a628c38fa22405ba 230 Pfam PF01618 MotA/TolQ/ExbB proton channel family 92 192 2.6E-26 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel AFE_2463 fd71019dd896d913834323269dab0ed4 396 SUPERFAMILY SSF56935 127 374 2.01E-9 T 12-10-2018 AFE_2463 fd71019dd896d913834323269dab0ed4 396 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 66 396 1.8E-66 T 12-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 SUPERFAMILY SSF50156 251 373 6.18E-19 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 Gene3D G3DSA:2.30.42.10 293 395 5.7E-23 T 12-10-2018 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 Gene3D G3DSA:2.30.42.10 403 494 1.1E-11 T 12-10-2018 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 SUPERFAMILY SSF50494 57 281 1.4E-55 T 12-10-2018 IPR009003 Peptidase S1, PA clan AFE_1646 22f0419a5d993b28435a871ea85b7307 494 Pfam PF13180 PDZ domain 294 384 7.8E-11 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 SMART SM00228 293 375 2.6E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 SMART SM00228 403 482 0.0082 T 12-10-2018 IPR001478 PDZ domain GO:0005515 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 SUPERFAMILY SSF50156 423 492 1.25E-11 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 Gene3D G3DSA:2.40.10.120 57 285 1.1E-67 T 12-10-2018 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 Pfam PF13365 Trypsin-like peptidase domain 120 254 1.4E-29 T 12-10-2018 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 PRINTS PR00834 HtrA/DegQ protease family signature 247 264 7.6E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 PRINTS PR00834 HtrA/DegQ protease family signature 129 141 7.6E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 PRINTS PR00834 HtrA/DegQ protease family signature 150 170 7.6E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 PRINTS PR00834 HtrA/DegQ protease family signature 225 242 7.6E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 PRINTS PR00834 HtrA/DegQ protease family signature 333 345 7.6E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1646 22f0419a5d993b28435a871ea85b7307 494 PRINTS PR00834 HtrA/DegQ protease family signature 190 214 7.6E-37 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFE_1861 1ab1481b80ad2b7603e5260931c83596 109 Gene3D G3DSA:3.30.1360.20 19 109 2.3E-31 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFE_1861 1ab1481b80ad2b7603e5260931c83596 109 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 19 106 4.8E-29 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFE_1861 1ab1481b80ad2b7603e5260931c83596 109 SUPERFAMILY SSF55248 19 108 7.06E-31 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFE_1861 1ab1481b80ad2b7603e5260931c83596 109 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 17 108 22.182 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFE_3097 055b330a973c0a1e8437b47d2c2889da 310 Pfam PF01636 Phosphotransferase enzyme family 28 245 4.2E-34 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase AFE_3097 055b330a973c0a1e8437b47d2c2889da 310 Gene3D G3DSA:3.90.1200.10 110 309 1.1E-64 T 12-10-2018 AFE_3097 055b330a973c0a1e8437b47d2c2889da 310 Gene3D G3DSA:3.30.200.20 1 102 2.7E-34 T 12-10-2018 AFE_3097 055b330a973c0a1e8437b47d2c2889da 310 Hamap MF_00301 Homoserine kinase [thrB]. 1 310 132.644 T 12-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 AFE_3097 055b330a973c0a1e8437b47d2c2889da 310 SUPERFAMILY SSF56112 5 307 4.52E-66 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily AFE_3097 055b330a973c0a1e8437b47d2c2889da 310 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 304 1.8E-102 T 12-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 AFE_1082 40184f6d0ffeab45404c2541fda89e80 165 TIGRFAM TIGR02747 TraV: type IV conjugative transfer system protein TraV 2 149 2.9E-49 T 12-10-2018 IPR014118 Type IV conjugative transfer system protein TraV AFE_1082 40184f6d0ffeab45404c2541fda89e80 165 Pfam PF09676 Type IV conjugative transfer system lipoprotein (TraV) 21 149 3.0E-23 T 12-10-2018 IPR014118 Type IV conjugative transfer system protein TraV AFE_1813 ade833cf20ef25daa60b0ae147c1ee1f 354 SUPERFAMILY SSF52518 4 339 2.74E-86 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold AFE_1813 ade833cf20ef25daa60b0ae147c1ee1f 354 Gene3D G3DSA:3.40.50.970 1 350 2.3E-112 T 12-10-2018 AFE_1813 ade833cf20ef25daa60b0ae147c1ee1f 354 Pfam PF00676 Dehydrogenase E1 component 12 265 6.9E-73 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 AFE_1226 b9df2b4975fb68e1c8cb1e94a64bcc38 875 SUPERFAMILY SSF52540 1 859 9.16E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1226 b9df2b4975fb68e1c8cb1e94a64bcc38 875 Gene3D G3DSA:3.40.50.300 623 869 1.3E-13 T 12-10-2018 AFE_0160 fc8b267b336a21ede5c8929dcc8239e5 152 Pfam PF02470 MlaD protein 38 116 7.8E-22 T 12-10-2018 IPR003399 Mce/MlaD AFE_0160 fc8b267b336a21ede5c8929dcc8239e5 152 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 147 2.5E-56 T 12-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 AFE_2583 8e7ec13b5d0e564ac88adc5249f1dd43 302 Pfam PF08443 RimK-like ATP-grasp domain 102 288 5.1E-33 T 12-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 AFE_2583 8e7ec13b5d0e564ac88adc5249f1dd43 302 Gene3D G3DSA:3.40.50.20 3 118 1.4E-23 T 12-10-2018 AFE_2583 8e7ec13b5d0e564ac88adc5249f1dd43 302 SUPERFAMILY SSF56059 93 290 7.26E-39 T 12-10-2018 AFE_2583 8e7ec13b5d0e564ac88adc5249f1dd43 302 Gene3D G3DSA:3.30.1490.20 119 183 1.4E-12 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFE_2583 8e7ec13b5d0e564ac88adc5249f1dd43 302 Gene3D G3DSA:3.30.470.80 184 296 1.8E-32 T 12-10-2018 AFE_2583 8e7ec13b5d0e564ac88adc5249f1dd43 302 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 7 288 4.4E-51 T 12-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 AFE_0285 66a5b5aafc7fa5dbac22cc579fa24acc 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.129 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0285 66a5b5aafc7fa5dbac22cc579fa24acc 103 SUPERFAMILY SSF141091 1 101 2.09E-38 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0285 66a5b5aafc7fa5dbac22cc579fa24acc 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.1E-38 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0285 66a5b5aafc7fa5dbac22cc579fa24acc 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 6.0E-41 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFE_0285 66a5b5aafc7fa5dbac22cc579fa24acc 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFE_3012 5d724433a4e20895543a002006b1825a 347 Pfam PF05159 Capsule polysaccharide biosynthesis protein 150 299 2.4E-31 T 12-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 AFE_3012 5d724433a4e20895543a002006b1825a 347 Pfam PF05159 Capsule polysaccharide biosynthesis protein 62 115 5.1E-7 T 12-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 AFE_3208 58e24757d06a091a29c3f2b51026f662 84 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 22 79 4.4E-18 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFE_3208 58e24757d06a091a29c3f2b51026f662 84 Gene3D G3DSA:1.20.20.10 1 84 3.4E-25 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3208 58e24757d06a091a29c3f2b51026f662 84 ProSitePatterns PS00605 ATP synthase c subunit signature. 42 63 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3208 58e24757d06a091a29c3f2b51026f662 84 Hamap MF_01396 ATP synthase subunit c [atpH]. 12 77 12.925 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFE_3208 58e24757d06a091a29c3f2b51026f662 84 SUPERFAMILY SSF81333 5 81 2.75E-17 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily AFE_3208 58e24757d06a091a29c3f2b51026f662 84 Pfam PF00137 ATP synthase subunit C 13 74 7.8E-10 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AFE_1235 007303627a61018a8897988dcd2ff5d5 222 SUPERFAMILY SSF52540 21 213 6.39E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1235 007303627a61018a8897988dcd2ff5d5 222 Gene3D G3DSA:3.40.50.300 8 220 4.3E-17 T 12-10-2018 AFE_2503 519988ee94b338a6ec7e89da15a660a2 342 Pfam PF06527 TniQ 2 126 1.9E-15 T 12-10-2018 IPR009492 TniQ AFE_2637 e0a82b66e746bfd5d041d13ad766e7a3 481 SUPERFAMILY SSF111283 23 479 4.32E-134 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 AFE_2637 e0a82b66e746bfd5d041d13ad766e7a3 481 Pfam PF01523 Putative modulator of DNA gyrase 38 331 1.9E-72 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AFE_2637 e0a82b66e746bfd5d041d13ad766e7a3 481 PIRSF PIRSF004919 20 480 3.2E-138 T 12-10-2018 IPR025502 TldD AFE_2637 e0a82b66e746bfd5d041d13ad766e7a3 481 Gene3D G3DSA:3.30.2290.10 19 239 1.3E-20 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal AFE_0045 bd1228b890cba6c2935f411d2f0edf9c 215 SMART SM00450 62 183 2.5E-13 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_0045 bd1228b890cba6c2935f411d2f0edf9c 215 SUPERFAMILY SSF52821 56 200 9.82E-24 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_0045 bd1228b890cba6c2935f411d2f0edf9c 215 Gene3D G3DSA:3.40.250.10 66 196 6.8E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily AFE_0045 bd1228b890cba6c2935f411d2f0edf9c 215 Pfam PF00581 Rhodanese-like domain 76 180 2.1E-13 T 12-10-2018 IPR001763 Rhodanese-like domain AFE_1694 c0d84bab8c2c0c4b4f8057bf37007bc8 222 Pfam PF04335 VirB8 protein 9 219 1.1E-38 T 12-10-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 AFE_1694 c0d84bab8c2c0c4b4f8057bf37007bc8 222 SUPERFAMILY SSF54427 81 221 4.16E-18 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFE_0642 be5451ec17069e4682ade4a7c4f1167b 66 SUPERFAMILY SSF54285 1 66 8.58E-19 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFE_0642 be5451ec17069e4682ade4a7c4f1167b 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 6.4E-23 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis AFE_0642 be5451ec17069e4682ade4a7c4f1167b 66 Pfam PF02597 ThiS family 3 66 5.0E-16 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFE_0642 be5451ec17069e4682ade4a7c4f1167b 66 Gene3D G3DSA:3.10.20.30 1 66 3.8E-23 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_2473 bfefec8127af0a45175f64961d507dbb 207 PIRSF PIRSF001296 1 193 1.8E-73 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFE_2473 bfefec8127af0a45175f64961d507dbb 207 Pfam PF02669 K+-transporting ATPase, c chain 6 187 1.6E-72 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFE_2473 bfefec8127af0a45175f64961d507dbb 207 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 4 188 5.6E-70 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFE_2473 bfefec8127af0a45175f64961d507dbb 207 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 189 34.879 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 AFE_0120 c7df6ce47c91bfee93eb96f0639afce3 68 Pfam PF11127 Protein of unknown function (DUF2892) 8 65 1.4E-21 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 AFE_2950 ca395896f4a0eff939ed60203ef3da4f 157 SUPERFAMILY SSF75217 1 152 6.28E-41 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases AFE_2950 ca395896f4a0eff939ed60203ef3da4f 157 Pfam PF02590 Predicted SPOUT methyltransferase 1 152 1.9E-39 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 AFE_2950 ca395896f4a0eff939ed60203ef3da4f 157 PIRSF PIRSF004505 1 153 1.3E-34 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 AFE_2950 ca395896f4a0eff939ed60203ef3da4f 157 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 153 24.46 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 AFE_2950 ca395896f4a0eff939ed60203ef3da4f 157 Gene3D G3DSA:3.40.1280.10 1 154 1.2E-40 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFE_2065 71dc36f9802a2506968acbf373dad3ac 165 Pfam PF02674 Colicin V production protein 5 140 1.8E-26 T 12-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 AFE_2830 4c6ca760ca24f04ad74f2a1aaf074ad8 142 Pfam PF07027 Protein of unknown function (DUF1318) 45 142 1.6E-19 T 12-10-2018 IPR008309 Uncharacterised conserved protein UCP025560 AFE_0275 79454485cf64d21a6f4f6ef48f72f611 203 SUPERFAMILY SSF52833 41 201 6.59E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0275 79454485cf64d21a6f4f6ef48f72f611 203 Gene3D G3DSA:3.40.30.10 48 203 4.0E-21 T 12-10-2018 AFE_0275 79454485cf64d21a6f4f6ef48f72f611 203 Pfam PF13098 Thioredoxin-like domain 53 120 2.5E-7 T 12-10-2018 IPR012336 Thioredoxin-like fold AFE_2270 8ec01caac00210f7140cc792ca9482bf 227 Pfam PF01618 MotA/TolQ/ExbB proton channel family 80 192 9.1E-27 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel AFE_1078 d4f3ec6de61accdf8826e37ff1911b61 92 TIGRFAM TIGR02762 TraL_TIGR: type IV conjugative transfer system protein TraL 4 83 1.0E-15 T 12-10-2018 IPR009838 Type IV conjugative transfer system, protein TraL GO:0000746|GO:0019867 AFE_1078 d4f3ec6de61accdf8826e37ff1911b61 92 Pfam PF07178 TraL protein 5 71 6.9E-16 T 12-10-2018 IPR009838 Type IV conjugative transfer system, protein TraL GO:0000746|GO:0019867 AFE_0409 b6bf281f7b384cae181b31b98de50b9d 161 Pfam PF08238 Sel1 repeat 97 112 14.0 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0409 b6bf281f7b384cae181b31b98de50b9d 161 Pfam PF08238 Sel1 repeat 114 148 5.2E-8 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0409 b6bf281f7b384cae181b31b98de50b9d 161 Gene3D G3DSA:1.25.40.10 65 160 1.6E-19 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0409 b6bf281f7b384cae181b31b98de50b9d 161 SMART SM00671 81 112 59.0 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0409 b6bf281f7b384cae181b31b98de50b9d 161 SMART SM00671 113 148 1.3E-6 T 12-10-2018 IPR006597 Sel1-like repeat AFE_0409 b6bf281f7b384cae181b31b98de50b9d 161 SUPERFAMILY SSF81901 75 153 4.45E-16 T 12-10-2018 AFE_0964 ef9b8ecb0c377c024566a393c0e57552 187 Pfam PF04241 Protein of unknown function (DUF423) 70 157 6.7E-21 T 12-10-2018 IPR006696 Protein of unknown function DUF423 AFE_1536 ccd1e86c96d343637baa7007d93ebc77 83 Pfam PF04319 NifZ domain 6 75 2.3E-25 T 12-10-2018 IPR007415 Nitrogenase MoFe maturation protein, NifZ GO:0009399 AFE_0265 1b8e5660df4ae5da4d0bf1265bc8cc82 376 Gene3D G3DSA:3.40.50.300 102 357 8.4E-86 T 12-10-2018 AFE_0265 1b8e5660df4ae5da4d0bf1265bc8cc82 376 SUPERFAMILY SSF52540 3 339 1.74E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0265 1b8e5660df4ae5da4d0bf1265bc8cc82 376 Gene3D G3DSA:3.30.450.90 1 101 1.6E-30 T 12-10-2018 AFE_0265 1b8e5660df4ae5da4d0bf1265bc8cc82 376 Pfam PF00437 Type II/IV secretion system protein 120 247 9.7E-34 T 12-10-2018 IPR001482 Type II/IV secretion system protein AFE_0265 1b8e5660df4ae5da4d0bf1265bc8cc82 376 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 345 9.8E-133 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 AFE_0538 3b09bbd9341e8b29729cf46b85a56f11 508 Pfam PF05670 Domain of unknown function (DUF814) 401 485 4.7E-19 T 12-10-2018 IPR008532 Domain of unknown function DUF814 AFE_0538 3b09bbd9341e8b29729cf46b85a56f11 508 Gene3D G3DSA:2.30.310.10 1 157 6.6E-8 T 12-10-2018 AFE_0538 3b09bbd9341e8b29729cf46b85a56f11 508 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 248 364 3.6E-8 T 12-10-2018 AFE_2888 7fb28e8d92f30179bed05e21497209a4 138 SUPERFAMILY SSF88723 5 128 9.53E-21 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_2888 7fb28e8d92f30179bed05e21497209a4 138 Gene3D G3DSA:3.40.50.1010 6 135 8.0E-9 T 12-10-2018 AFE_2888 7fb28e8d92f30179bed05e21497209a4 138 Pfam PF01850 PIN domain 7 118 9.5E-13 T 12-10-2018 IPR002716 PIN domain AFE_1695 75fbe73ffc7d9c76a7eb6e4c25bf1e9d 381 Gene3D G3DSA:2.60.40.2500 297 380 5.1E-12 T 12-10-2018 IPR038161 VirB9/CagX/TrbG, C-terminal domain superfamily AFE_1695 75fbe73ffc7d9c76a7eb6e4c25bf1e9d 381 Pfam PF03524 Conjugal transfer protein 140 378 2.8E-23 T 12-10-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX AFE_1745 6e047eeef93f0090b7b19cd907dc047b 177 Gene3D G3DSA:1.20.1290.10 14 177 1.1E-26 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFE_1745 6e047eeef93f0090b7b19cd907dc047b 177 SUPERFAMILY SSF69118 1 176 4.71E-36 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFE_0086 759fe447382069297ebc23f3fd9a6082 137 Gene3D G3DSA:3.40.50.1010 1 131 8.0E-9 T 12-10-2018 AFE_0086 759fe447382069297ebc23f3fd9a6082 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 134 9.589 T 12-10-2018 IPR022907 VapC family GO:0004540 AFE_0086 759fe447382069297ebc23f3fd9a6082 137 SUPERFAMILY SSF88723 2 135 6.73E-15 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_0086 759fe447382069297ebc23f3fd9a6082 137 Pfam PF01850 PIN domain 3 128 5.5E-10 T 12-10-2018 IPR002716 PIN domain AFE_0889 8e8a333043a10de027b83b74a6bdd103 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 12 78 2.4E-6 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM AFE_0889 8e8a333043a10de027b83b74a6bdd103 84 SUPERFAMILY SSF143120 12 71 2.62E-5 T 12-10-2018 IPR036165 YefM-like superfamily AFE_1095 b440f22876b0a145f7544a9bf574755c 422 Pfam PF09673 Type-F conjugative transfer system pilin assembly protein 118 203 3.0E-14 T 12-10-2018 IPR019106 Type-F conjugative transfer system pilin assembly protein TrbC AFE_0102 9036555ae66a777254e395919645d071 378 Pfam PF12704 MacB-like periplasmic core domain 21 227 2.4E-8 T 12-10-2018 IPR025857 MacB-like periplasmic core domain AFE_0102 9036555ae66a777254e395919645d071 378 Pfam PF02687 FtsX-like permease family 285 372 4.7E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFE_1390 af3fe6b32be0f77e1c7496771c5bc820 585 Gene3D G3DSA:3.40.50.300 333 578 1.3E-75 T 12-10-2018 AFE_1390 af3fe6b32be0f77e1c7496771c5bc820 585 Pfam PF00005 ABC transporter 360 507 3.6E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_1390 af3fe6b32be0f77e1c7496771c5bc820 585 SUPERFAMILY SSF52540 337 573 6.91E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1390 af3fe6b32be0f77e1c7496771c5bc820 585 SMART SM00382 368 556 1.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1390 af3fe6b32be0f77e1c7496771c5bc820 585 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 9 538 1.5E-135 T 12-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 AFE_1390 af3fe6b32be0f77e1c7496771c5bc820 585 SUPERFAMILY SSF90123 6 326 1.44E-41 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_1390 af3fe6b32be0f77e1c7496771c5bc820 585 Gene3D G3DSA:1.20.1560.10 4 324 9.4E-32 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFE_0597 1c9b2b111af9a6e7ab705060850cc474 340 Gene3D G3DSA:3.40.50.300 129 334 4.1E-74 T 12-10-2018 AFE_0597 1c9b2b111af9a6e7ab705060850cc474 340 SUPERFAMILY SSF52540 136 311 3.92E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_0597 1c9b2b111af9a6e7ab705060850cc474 340 Pfam PF02562 PhoH-like protein 131 334 1.5E-92 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 AFE_3150 d5e51e8d5262ae0f1c558682d15398c6 254 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 160 238 5.3E-9 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3150 d5e51e8d5262ae0f1c558682d15398c6 254 SUPERFAMILY SSF49503 133 251 2.11E-34 T 12-10-2018 IPR008972 Cupredoxin AFE_3150 d5e51e8d5262ae0f1c558682d15398c6 254 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 179 233 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3150 d5e51e8d5262ae0f1c558682d15398c6 254 Gene3D G3DSA:2.60.40.2600 132 253 3.0E-39 T 12-10-2018 AFE_0054 7d9c9cd5a94d8af6e9905809c778029b 216 Pfam PF01914 MarC family integral membrane protein 7 206 7.8E-55 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFE_0054 7d9c9cd5a94d8af6e9905809c778029b 216 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 9 203 5.9E-56 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AFE_0502 e87f59ed7e200a721c891fa54360e489 141 Gene3D G3DSA:3.10.180.70 12 141 2.3E-38 T 12-10-2018 AFE_0502 e87f59ed7e200a721c891fa54360e489 141 SUPERFAMILY SSF54593 36 139 1.46E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFE_0502 e87f59ed7e200a721c891fa54360e489 141 PIRSF PIRSF021700 13 141 2.0E-45 T 12-10-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase AFE_0502 e87f59ed7e200a721c891fa54360e489 141 SUPERFAMILY SSF54909 5 47 3.67E-9 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel AFE_0502 e87f59ed7e200a721c891fa54360e489 141 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 29 101 4.7E-26 T 12-10-2018 IPR028973 PhnB-like AFE_1499 3416613ba646c66eabe290735a28be7a 553 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 355 468 1.3E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFE_1499 3416613ba646c66eabe290735a28be7a 553 SUPERFAMILY SSF52540 347 528 2.89E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1499 3416613ba646c66eabe290735a28be7a 553 SMART SM00382 351 478 0.0022 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1499 3416613ba646c66eabe290735a28be7a 553 Gene3D G3DSA:3.40.50.300 317 495 1.1E-26 T 12-10-2018 AFE_0789 eef3c945cecdd4c6dc55a43f77ebf8b9 357 SUPERFAMILY SSF55298 217 349 1.28E-12 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFE_0789 eef3c945cecdd4c6dc55a43f77ebf8b9 357 Gene3D G3DSA:3.30.1330.40 223 351 3.7E-16 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFE_2059 f36520f3a828c2bcb29825bf590f0c02 371 Gene3D G3DSA:3.20.20.105 1 366 1.5E-158 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFE_2059 f36520f3a828c2bcb29825bf590f0c02 371 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 4 363 2.7E-152 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFE_2059 f36520f3a828c2bcb29825bf590f0c02 371 SUPERFAMILY SSF51713 2 362 2.62E-153 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFE_2059 f36520f3a828c2bcb29825bf590f0c02 371 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 4 363 8.9E-158 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFE_2059 f36520f3a828c2bcb29825bf590f0c02 371 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 2 362 54.835 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFE_2059 f36520f3a828c2bcb29825bf590f0c02 371 Pfam PF01702 Queuine tRNA-ribosyltransferase 127 359 6.0E-88 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFE_2352 36410735390580dc1fd0448a102e475b 335 SUPERFAMILY SSF46785 7 87 1.41E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2352 36410735390580dc1fd0448a102e475b 335 Pfam PF13649 Methyltransferase domain 170 265 2.7E-15 T 12-10-2018 AFE_2352 36410735390580dc1fd0448a102e475b 335 SUPERFAMILY SSF53335 164 320 5.06E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2352 36410735390580dc1fd0448a102e475b 335 Gene3D G3DSA:3.40.50.150 148 324 5.2E-32 T 12-10-2018 AFE_1901 a3cd81f461d4f91ab7d3beb678d56014 236 Gene3D G3DSA:1.10.8.60 167 232 2.2E-19 T 12-10-2018 AFE_1901 a3cd81f461d4f91ab7d3beb678d56014 236 Pfam PF00308 Bacterial dnaA protein 26 213 1.3E-10 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA AFE_1901 a3cd81f461d4f91ab7d3beb678d56014 236 Gene3D G3DSA:3.40.50.300 2 163 5.0E-20 T 12-10-2018 AFE_1901 a3cd81f461d4f91ab7d3beb678d56014 236 SUPERFAMILY SSF52540 16 210 8.05E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1901 a3cd81f461d4f91ab7d3beb678d56014 236 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 5 231 3.9E-67 T 12-10-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 AFE_0711 0b13e57522bc7cfc9770329f330ef96f 398 Pfam PF01436 NHL repeat 57 79 4.2E-4 T 12-10-2018 IPR001258 NHL repeat GO:0005515 AFE_0711 0b13e57522bc7cfc9770329f330ef96f 398 Gene3D G3DSA:2.120.10.30 29 397 5.3E-18 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFE_0711 0b13e57522bc7cfc9770329f330ef96f 398 SUPERFAMILY SSF101898 49 396 3.4E-13 T 12-10-2018 AFE_2330 57800325dc8a618ae3c1a9ab47cb5726 264 Pfam PF03988 Repeat of Unknown Function (DUF347) 142 189 8.0E-10 T 12-10-2018 IPR007136 Protein of unknown function DUF347 AFE_2330 57800325dc8a618ae3c1a9ab47cb5726 264 Pfam PF03988 Repeat of Unknown Function (DUF347) 77 127 1.4E-10 T 12-10-2018 IPR007136 Protein of unknown function DUF347 AFE_2330 57800325dc8a618ae3c1a9ab47cb5726 264 Pfam PF03988 Repeat of Unknown Function (DUF347) 25 73 2.3E-7 T 12-10-2018 IPR007136 Protein of unknown function DUF347 AFE_2330 57800325dc8a618ae3c1a9ab47cb5726 264 Pfam PF03988 Repeat of Unknown Function (DUF347) 197 251 7.6E-12 T 12-10-2018 IPR007136 Protein of unknown function DUF347 AFE_2629 eb78742670861d779b50dc6dcacf5b81 158 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 3.6E-77 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2629 eb78742670861d779b50dc6dcacf5b81 158 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.297 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2629 eb78742670861d779b50dc6dcacf5b81 158 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2629 eb78742670861d779b50dc6dcacf5b81 158 SUPERFAMILY SSF56770 9 153 1.23E-66 T 12-10-2018 AFE_2629 eb78742670861d779b50dc6dcacf5b81 158 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 146 2.3E-22 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2629 eb78742670861d779b50dc6dcacf5b81 158 Gene3D G3DSA:3.40.50.12280 2 158 1.6E-79 T 12-10-2018 AFE_2816 80fbf67487c5c088e70e7856c6cb6861 146 Pfam PF13767 Domain of unknown function (DUF4168) 64 141 3.0E-14 T 12-10-2018 IPR025433 Domain of unknown function DUF4168 AFE_3127 6fd57bacdbf017c492b39e8fee02eb70 117 Gene3D G3DSA:3.40.50.1400 2 117 9.0E-23 T 12-10-2018 AFE_3127 6fd57bacdbf017c492b39e8fee02eb70 117 SUPERFAMILY SSF53800 3 113 1.44E-23 T 12-10-2018 AFE_3127 6fd57bacdbf017c492b39e8fee02eb70 117 Pfam PF01903 CbiX 11 111 1.5E-17 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFE_2314 a548bd6b8d05eea351c55c136689f5dd 160 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 80 1.7E-10 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFE_2314 a548bd6b8d05eea351c55c136689f5dd 160 PIRSF PIRSF000709 1 91 1.4E-7 T 12-10-2018 AFE_2314 a548bd6b8d05eea351c55c136689f5dd 160 Gene3D G3DSA:3.40.50.1240 2 160 1.6E-30 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFE_2314 a548bd6b8d05eea351c55c136689f5dd 160 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 151 1.8E-22 T 12-10-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0101006 AFE_2314 a548bd6b8d05eea351c55c136689f5dd 160 SMART SM00855 2 114 1.5E-6 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFE_2314 a548bd6b8d05eea351c55c136689f5dd 160 SUPERFAMILY SSF53254 1 140 8.51E-17 T 12-10-2018 IPR029033 Histidine phosphatase superfamily AFE_2804 b29c53792913a3aff9a179411f12fb6b 159 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 142 1.7E-12 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase AFE_2804 b29c53792913a3aff9a179411f12fb6b 159 SUPERFAMILY SSF55961 1 142 6.48E-26 T 12-10-2018 AFE_2804 b29c53792913a3aff9a179411f12fb6b 159 Gene3D G3DSA:3.30.530.20 1 143 9.2E-27 T 12-10-2018 IPR023393 START-like domain superfamily AFE_1884 66b655564ff775d27993382164dcf838 88 SUPERFAMILY SSF50182 10 71 7.85E-23 T 12-10-2018 IPR010920 LSM domain superfamily AFE_1884 66b655564ff775d27993382164dcf838 88 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 9 67 7.8E-29 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AFE_1884 66b655564ff775d27993382164dcf838 88 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 6 67 27.32 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AFE_1884 66b655564ff775d27993382164dcf838 88 Pfam PF17209 Hfq protein 10 71 9.6E-30 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AFE_1884 66b655564ff775d27993382164dcf838 88 Gene3D G3DSA:2.30.30.100 4 79 7.4E-30 T 12-10-2018 AFE_0850 202419d51c08c9dd340933f766178411 155 Hamap MF_00599 Cell division protein FtsB [ftsB]. 53 141 23.288 T 12-10-2018 IPR023081 Cell division protein FtsB AFE_0850 202419d51c08c9dd340933f766178411 155 Pfam PF04977 Septum formation initiator 63 139 4.7E-17 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC AFE_2170 f81d5ed5993b239a9f4e0e04d297ee93 256 Pfam PF01522 Polysaccharide deacetylase 81 213 1.7E-25 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFE_2170 f81d5ed5993b239a9f4e0e04d297ee93 256 SUPERFAMILY SSF88713 43 221 7.66E-36 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFE_2170 f81d5ed5993b239a9f4e0e04d297ee93 256 Gene3D G3DSA:3.20.20.370 22 251 9.5E-63 T 12-10-2018 AFE_1086 04fa323a0a1929b3da76cd8bc899a261 307 SUPERFAMILY SSF52540 3 58 3.13E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3078 9d14ddfc23c22f10fc606a459554ac10 70 Pfam PF11127 Protein of unknown function (DUF2892) 1 64 2.2E-22 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 AFE_3304 ab09dea880deeb6d50b0d12ca3f430a1 217 Gene3D G3DSA:3.20.20.70 4 216 4.6E-57 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_3304 ab09dea880deeb6d50b0d12ca3f430a1 217 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 9 213 24.989 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFE_3304 ab09dea880deeb6d50b0d12ca3f430a1 217 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 11 207 1.2E-54 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFE_3304 ab09dea880deeb6d50b0d12ca3f430a1 217 SUPERFAMILY SSF51391 9 213 1.23E-58 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFE_3304 ab09dea880deeb6d50b0d12ca3f430a1 217 Pfam PF02581 Thiamine monophosphate synthase 11 195 9.5E-51 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFE_0433 e78b6efcffc836247a5da30a1947a364 182 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 176 28.674 T 12-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 AFE_0433 e78b6efcffc836247a5da30a1947a364 182 Gene3D G3DSA:2.60.120.10 1 171 6.1E-49 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_0433 e78b6efcffc836247a5da30a1947a364 182 SUPERFAMILY SSF51182 10 174 2.19E-33 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_0433 e78b6efcffc836247a5da30a1947a364 182 Pfam PF03079 ARD/ARD' family 69 169 1.6E-23 T 12-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 AFE_0482 459225908d2afefd7a1d58f89465a12e 186 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 23 174 3.1E-30 T 12-10-2018 IPR018639 Domain of unknown function DUF2062 AFE_2710 653a5b3c0abf1d823cb47a055b9a2f09 79 Pfam PF04964 Flp/Fap pilin component 31 74 6.5E-17 T 12-10-2018 IPR007047 Flp/Fap pilin component AFE_2913 4b060543f136f21f0c9a4b8b145a9d65 491 Pfam PF04293 SpoVR like protein 10 439 2.2E-152 T 12-10-2018 IPR007390 Sporulation stage V, protein R AFE_0605 f8be2909ee1e8a904aba54dbf22fa4d6 269 SUPERFAMILY SSF81345 3 251 1.83E-28 T 12-10-2018 IPR037294 ABC transporter, BtuC-like AFE_0605 f8be2909ee1e8a904aba54dbf22fa4d6 269 Pfam PF00950 ABC 3 transport family 4 253 1.9E-36 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AFE_2771 7272d580d00f21230214aa8befd32780 79 SMART SM00966 10 50 0.0056 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_2771 7272d580d00f21230214aa8befd32780 79 SUPERFAMILY SSF89447 7 72 9.94E-12 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFE_2771 7272d580d00f21230214aa8befd32780 79 Gene3D G3DSA:2.10.260.10 5 76 3.0E-12 T 12-10-2018 AFE_2771 7272d580d00f21230214aa8befd32780 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 56 2.5E-8 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFE_2007 4990698171deede4cd605734b5db93f1 228 Pfam PF01841 Transglutaminase-like superfamily 43 148 1.9E-15 T 12-10-2018 IPR002931 Transglutaminase-like AFE_2007 4990698171deede4cd605734b5db93f1 228 SUPERFAMILY SSF54001 48 158 1.23E-19 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFE_2007 4990698171deede4cd605734b5db93f1 228 Gene3D G3DSA:3.10.620.30 6 173 1.0E-15 T 12-10-2018 AFE_2504 d6b00e6b2b0a71587f61752941834afb 294 Gene3D G3DSA:3.40.50.300 35 208 1.8E-17 T 12-10-2018 AFE_2504 d6b00e6b2b0a71587f61752941834afb 294 Pfam PF05621 Bacterial TniB protein 21 274 8.4E-103 T 12-10-2018 IPR008868 Bacterial TniB AFE_2504 d6b00e6b2b0a71587f61752941834afb 294 SUPERFAMILY SSF52540 43 278 2.84E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1327 5e345d49a7b72cfb4273737c8a45bec9 251 SUPERFAMILY SSF160940 118 206 2.48E-5 T 12-10-2018 AFE_3238 f5b5adc1c0f132918c6d0108e2ab8a54 105 Gene3D G3DSA:3.40.30.10 6 105 7.1E-29 T 12-10-2018 AFE_3238 f5b5adc1c0f132918c6d0108e2ab8a54 105 SUPERFAMILY SSF52833 6 104 1.79E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1209 b8b65aebd76c584b355f4e4e06ce1415 3484 SUPERFAMILY SSF103515 3216 3484 4.58E-27 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily AFE_1209 b8b65aebd76c584b355f4e4e06ce1415 3484 PRINTS PR01228 Eggshell protein signature 166 177 9.0E-6 T 12-10-2018 AFE_1209 b8b65aebd76c584b355f4e4e06ce1415 3484 PRINTS PR01228 Eggshell protein signature 310 328 9.0E-6 T 12-10-2018 AFE_1209 b8b65aebd76c584b355f4e4e06ce1415 3484 PRINTS PR01228 Eggshell protein signature 242 257 9.0E-6 T 12-10-2018 AFE_1209 b8b65aebd76c584b355f4e4e06ce1415 3484 PRINTS PR01228 Eggshell protein signature 273 283 9.0E-6 T 12-10-2018 AFE_1209 b8b65aebd76c584b355f4e4e06ce1415 3484 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 24 2.5E-9 T 12-10-2018 IPR024973 ESPR domain AFE_1209 b8b65aebd76c584b355f4e4e06ce1415 3484 SMART SM00869 3221 3474 3.8E-15 T 12-10-2018 IPR005546 Autotransporter beta-domain AFE_2086 feccafa17fb9e614b6f2113e1954fdb0 145 SUPERFAMILY SSF49764 8 144 9.42E-43 T 12-10-2018 IPR008978 HSP20-like chaperone AFE_2086 feccafa17fb9e614b6f2113e1954fdb0 145 Gene3D G3DSA:2.60.40.790 3 144 2.6E-43 T 12-10-2018 IPR008978 HSP20-like chaperone AFE_2086 feccafa17fb9e614b6f2113e1954fdb0 145 Pfam PF00011 Hsp20/alpha crystallin family 43 144 1.1E-27 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain AFE_2328 764eacaa04f5da94781303c07d7a3371 196 Pfam PF01292 Prokaryotic cytochrome b561 22 191 7.8E-26 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFE_2328 764eacaa04f5da94781303c07d7a3371 196 SUPERFAMILY SSF81342 17 191 1.49E-22 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFE_1361 70a3977c9b62993323f5431ad418bc9a 97 SUPERFAMILY SSF47598 17 74 1.71E-16 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 AFE_1361 70a3977c9b62993323f5431ad418bc9a 97 Gene3D G3DSA:1.10.1220.10 26 75 5.3E-16 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFE_0674 55234f10dbfe9525d26a8a38d1068f89 143 Pfam PF01592 NifU-like N terminal domain 2 125 1.3E-56 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AFE_0674 55234f10dbfe9525d26a8a38d1068f89 143 Gene3D G3DSA:3.90.1010.10 1 132 2.4E-59 T 12-10-2018 AFE_0674 55234f10dbfe9525d26a8a38d1068f89 143 SUPERFAMILY SSF82649 1 125 2.15E-49 T 12-10-2018 AFE_0674 55234f10dbfe9525d26a8a38d1068f89 143 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 3.7E-69 T 12-10-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AFE_1484 a1956f8aa94e3f991224841f5da832a2 398 SUPERFAMILY SSF56935 27 336 2.93E-20 T 12-10-2018 AFE_1484 a1956f8aa94e3f991224841f5da832a2 398 Pfam PF07715 TonB-dependent Receptor Plug Domain 69 152 1.7E-5 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain AFE_2158 e31343726e18e2b03d96d1187676993b 301 Gene3D G3DSA:3.40.190.290 93 297 1.1E-47 T 12-10-2018 AFE_2158 e31343726e18e2b03d96d1187676993b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2158 e31343726e18e2b03d96d1187676993b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2158 e31343726e18e2b03d96d1187676993b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2158 e31343726e18e2b03d96d1187676993b 301 SUPERFAMILY SSF53850 93 295 7.85E-51 T 12-10-2018 AFE_2158 e31343726e18e2b03d96d1187676993b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.1E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFE_2158 e31343726e18e2b03d96d1187676993b 301 Gene3D G3DSA:1.10.10.10 2 90 6.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_2158 e31343726e18e2b03d96d1187676993b 301 Pfam PF03466 LysR substrate binding domain 91 293 4.6E-58 T 12-10-2018 IPR005119 LysR, substrate-binding AFE_2158 e31343726e18e2b03d96d1187676993b 301 SUPERFAMILY SSF46785 2 85 3.18E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFE_2316 8f78378498b7bda9a608588453ae1cd4 178 Pfam PF03843 Outer membrane lipoprotein Slp family 16 168 1.5E-36 T 12-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 AFE_2316 8f78378498b7bda9a608588453ae1cd4 178 PIRSF PIRSF004982 1 178 1.2E-40 T 12-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 AFE_0213 cd8757e8b25578d5114e4dfd7aa683e5 87 Pfam PF04999 Cell division protein FtsL 4 85 7.1E-18 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 AFE_0213 cd8757e8b25578d5114e4dfd7aa683e5 87 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 5 84 2.8E-21 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 AFE_0213 cd8757e8b25578d5114e4dfd7aa683e5 87 Hamap MF_00910 Cell division protein FtsL [ftsL]. 1 84 15.883 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 AFE_1085 2367952d2e2d68cef58f7132675cb215 274 Gene3D G3DSA:3.10.450.70 35 103 7.1E-7 T 12-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 AFE_1085 2367952d2e2d68cef58f7132675cb215 274 Gene3D G3DSA:3.40.30.10 127 271 2.9E-30 T 12-10-2018 AFE_1085 2367952d2e2d68cef58f7132675cb215 274 Pfam PF13098 Thioredoxin-like domain 138 253 2.1E-12 T 12-10-2018 IPR012336 Thioredoxin-like fold AFE_1085 2367952d2e2d68cef58f7132675cb215 274 SUPERFAMILY SSF54423 70 94 9.03E-5 T 12-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 AFE_1085 2367952d2e2d68cef58f7132675cb215 274 SUPERFAMILY SSF52833 120 265 1.12E-21 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_0233 14b7870b654987c33ee67d7d3f2a33f2 315 Pfam PF00535 Glycosyl transferase family 2 4 145 9.7E-18 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFE_0233 14b7870b654987c33ee67d7d3f2a33f2 315 Gene3D G3DSA:3.90.550.10 1 227 5.4E-38 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0233 14b7870b654987c33ee67d7d3f2a33f2 315 SUPERFAMILY SSF53448 1 259 4.42E-44 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0528 42493f82513ccf994e4bb33e85d376a1 149 Pfam PF10116 Protein required for attachment to host cells 6 143 2.0E-40 T 12-10-2018 IPR019291 Host attachment protein AFE_2412 1584fb191286e69449e17c9bdb62c83a 708 Gene3D G3DSA:3.50.30.10 599 703 7.9E-30 T 12-10-2018 AFE_2412 1584fb191286e69449e17c9bdb62c83a 708 SUPERFAMILY SSF52009 597 700 1.24E-26 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AFE_2412 1584fb191286e69449e17c9bdb62c83a 708 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 8 144 2.2E-18 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AFE_2412 1584fb191286e69449e17c9bdb62c83a 708 Pfam PF00391 PEP-utilising enzyme, mobile domain 628 697 2.0E-21 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFE_2412 1584fb191286e69449e17c9bdb62c83a 708 Gene3D G3DSA:3.30.470.20 4 142 6.7E-30 T 12-10-2018 AFE_2412 1584fb191286e69449e17c9bdb62c83a 708 SUPERFAMILY SSF56059 6 177 8.95E-22 T 12-10-2018 AFE_1038 dc5825bce006b9a763f619129b1e2c16 249 TIGRFAM TIGR03114 cas8u_csf1: CRISPR type AFERR-associated protein Csf1 31 233 1.0E-100 T 12-10-2018 IPR017545 CRISPR-associated protein, Csf1 family AFE_2454 1c6f9839d571d28b9b6e24f0d62bab0d 533 Gene3D G3DSA:1.20.1530.20 5 397 4.7E-15 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily AFE_2454 1c6f9839d571d28b9b6e24f0d62bab0d 533 Pfam PF00999 Sodium/hydrogen exchanger family 9 394 4.9E-70 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFE_1152 ef9730c36602e4725865d9899de0dfed 181 Gene3D G3DSA:3.30.40.60 69 158 3.5E-24 T 12-10-2018 AFE_1152 ef9730c36602e4725865d9899de0dfed 181 Pfam PF14279 HNH endonuclease 90 143 1.1E-20 T 12-10-2018 IPR029471 HNH endonuclease 5 AFE_1152 ef9730c36602e4725865d9899de0dfed 181 SMART SM00507 77 130 1.2E-14 T 12-10-2018 IPR003615 HNH nuclease AFE_0631 ba3fecb625c46c2a8e63ab636068c0d3 321 Gene3D G3DSA:2.60.40.420 117 293 6.0E-42 T 12-10-2018 IPR008972 Cupredoxin AFE_0631 ba3fecb625c46c2a8e63ab636068c0d3 321 SUPERFAMILY SSF81464 33 121 1.06E-14 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0631 ba3fecb625c46c2a8e63ab636068c0d3 321 Gene3D G3DSA:1.10.287.90 33 116 3.5E-21 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0631 ba3fecb625c46c2a8e63ab636068c0d3 321 SUPERFAMILY SSF49503 132 292 2.31E-37 T 12-10-2018 IPR008972 Cupredoxin AFE_0631 ba3fecb625c46c2a8e63ab636068c0d3 321 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 159 232 1.4E-5 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_0631 ba3fecb625c46c2a8e63ab636068c0d3 321 Pfam PF06481 COX Aromatic Rich Motif 249 295 2.2E-13 T 12-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 AFE_2805 ba8965541865b2cf0ba468a300dd0119 161 Pfam PF07883 Cupin domain 49 119 1.6E-18 T 12-10-2018 IPR013096 Cupin 2, conserved barrel AFE_2805 ba8965541865b2cf0ba468a300dd0119 161 SUPERFAMILY SSF51182 11 148 3.05E-31 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_2805 ba8965541865b2cf0ba468a300dd0119 161 Gene3D G3DSA:2.60.120.10 2 148 1.3E-51 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_2457 0f516b4e953630d9f6dc8a3e87d9bde6 539 Gene3D G3DSA:1.20.1740.10 12 462 4.6E-58 T 12-10-2018 AFE_2457 0f516b4e953630d9f6dc8a3e87d9bde6 539 Pfam PF13520 Amino acid permease 20 426 1.1E-38 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_2457 0f516b4e953630d9f6dc8a3e87d9bde6 539 PIRSF PIRSF006060 8 468 3.3E-60 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFE_0228 45a8e85bf9ef398f4929b93446b1d369 320 Pfam PF00535 Glycosyl transferase family 2 5 165 4.0E-32 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFE_0228 45a8e85bf9ef398f4929b93446b1d369 320 SUPERFAMILY SSF53448 2 260 7.03E-49 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_0228 45a8e85bf9ef398f4929b93446b1d369 320 Gene3D G3DSA:3.90.550.10 1 229 1.4E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_2556 1011bfa648579569e08878cc7ae381b2 156 SUPERFAMILY SSF75169 4 155 5.3E-20 T 12-10-2018 IPR027396 DsrEFH-like AFE_2556 1011bfa648579569e08878cc7ae381b2 156 Gene3D G3DSA:3.40.1260.10 1 156 5.1E-42 T 12-10-2018 IPR027396 DsrEFH-like AFE_2556 1011bfa648579569e08878cc7ae381b2 156 Pfam PF13686 DsrE/DsrF/DrsH-like family 3 155 4.7E-56 T 12-10-2018 IPR032836 DsrE2-like family AFE_1548 c994f3bbcdeef1395cc165e676eabbd7 130 Pfam PF01152 Bacterial-like globin 10 128 1.8E-35 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 AFE_1548 c994f3bbcdeef1395cc165e676eabbd7 130 SUPERFAMILY SSF46458 8 129 1.79E-36 T 12-10-2018 IPR009050 Globin-like superfamily AFE_1548 c994f3bbcdeef1395cc165e676eabbd7 130 Gene3D G3DSA:1.10.490.10 3 130 9.2E-43 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFE_0685 cba2d27128b2b3c6930a92df993c85ba 324 Gene3D G3DSA:1.20.120.1870 191 323 8.8E-20 T 12-10-2018 AFE_0685 cba2d27128b2b3c6930a92df993c85ba 324 Pfam PF13310 Virulence protein RhuM family 60 128 9.1E-23 T 12-10-2018 IPR011204 Virulence protein RhuM-like AFE_0685 cba2d27128b2b3c6930a92df993c85ba 324 SUPERFAMILY SSF140931 235 278 4.45E-6 T 12-10-2018 IPR036597 Fido-like domain superfamily AFE_0685 cba2d27128b2b3c6930a92df993c85ba 324 Pfam PF02661 Fic/DOC family 218 273 4.3E-10 T 12-10-2018 IPR003812 Fido domain AFE_2508 616ed8e123b5f184deea02d60ce2c272 125 Pfam PF02635 DsrE/DsrF-like family 10 100 2.4E-10 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFE_2508 616ed8e123b5f184deea02d60ce2c272 125 SUPERFAMILY SSF75169 8 125 6.06E-16 T 12-10-2018 IPR027396 DsrEFH-like AFE_2508 616ed8e123b5f184deea02d60ce2c272 125 Gene3D G3DSA:3.40.1260.10 1 125 1.1E-27 T 12-10-2018 IPR027396 DsrEFH-like AFE_0698 8dff911ea7750e45828ec86ac3156704 284 Pfam PF00756 Putative esterase 24 274 1.8E-55 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 AFE_0698 8dff911ea7750e45828ec86ac3156704 284 Gene3D G3DSA:3.40.50.1820 5 283 2.1E-84 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_0698 8dff911ea7750e45828ec86ac3156704 284 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 8 280 1.4E-126 T 12-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 AFE_0698 8dff911ea7750e45828ec86ac3156704 284 SUPERFAMILY SSF53474 4 277 2.13E-77 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_1234 a5381b4ae050f5daf1c6dc2ab1e5e1be 107 Pfam PF13488 Glycine zipper 35 74 5.9E-10 T 12-10-2018 IPR039567 Glycine zipper domain AFE_2938 dd7595b0957ecebdc8fb03847b2b53c4 115 Pfam PF05717 IS66 Orf2 like protein 8 102 8.3E-38 T 12-10-2018 IPR008878 Transposase IS66, Orf2 AFE_2469 dd7595b0957ecebdc8fb03847b2b53c4 115 Pfam PF05717 IS66 Orf2 like protein 8 102 8.3E-38 T 12-10-2018 IPR008878 Transposase IS66, Orf2 AFE_2724 61a54e665345ffce7f2c67121a794f38 204 Pfam PF02036 SCP-2 sterol transfer family 69 156 2.3E-11 T 12-10-2018 IPR003033 SCP2 sterol-binding domain AFE_2724 61a54e665345ffce7f2c67121a794f38 204 SUPERFAMILY SSF55718 59 162 6.47E-14 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AFE_0058 722d6c1c3a63fad53fb02bc86cf86837 203 Pfam PF01553 Acyltransferase 41 153 7.3E-17 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFE_0058 722d6c1c3a63fad53fb02bc86cf86837 203 SMART SM00563 48 156 5.8E-21 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFE_0058 722d6c1c3a63fad53fb02bc86cf86837 203 SUPERFAMILY SSF69593 40 202 5.23E-25 T 12-10-2018 AFE_2702 a6b7970a6ce6eda4fd6dc294297677cb 444 Gene3D G3DSA:3.40.50.300 192 431 5.9E-72 T 12-10-2018 AFE_2702 a6b7970a6ce6eda4fd6dc294297677cb 444 Pfam PF00437 Type II/IV secretion system protein 96 371 2.8E-77 T 12-10-2018 IPR001482 Type II/IV secretion system protein AFE_2702 a6b7970a6ce6eda4fd6dc294297677cb 444 SUPERFAMILY SSF52540 75 404 1.12E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2702 a6b7970a6ce6eda4fd6dc294297677cb 444 Gene3D G3DSA:3.30.450.380 17 189 3.7E-34 T 12-10-2018 AFE_0975 1d8bcb86dcbdbc42c7735684c27975e5 80 SUPERFAMILY SSF54285 1 80 1.01E-17 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFE_0975 1d8bcb86dcbdbc42c7735684c27975e5 80 Gene3D G3DSA:3.10.20.30 2 80 3.5E-19 T 12-10-2018 IPR012675 Beta-grasp domain superfamily AFE_0975 1d8bcb86dcbdbc42c7735684c27975e5 80 Pfam PF02597 ThiS family 4 80 1.3E-15 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFE_0279 61e8eb7c17f821fe39da91b3a8fa1ee5 115 Pfam PF04355 SmpA / OmlA family 30 98 1.6E-19 T 12-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 AFE_0279 61e8eb7c17f821fe39da91b3a8fa1ee5 115 Gene3D G3DSA:3.30.1450.10 29 110 4.9E-22 T 12-10-2018 IPR037873 BamE-like AFE_0279 61e8eb7c17f821fe39da91b3a8fa1ee5 115 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 4 111 24.051 T 12-10-2018 IPR026592 Outer membrane protein assembly factor BamE AFE_1631 b8a6594d50d66a355fa6118b9145ba2c 99 Gene3D G3DSA:1.10.260.40 36 93 4.5E-6 T 12-10-2018 AFE_1631 b8a6594d50d66a355fa6118b9145ba2c 99 SMART SM00530 42 95 0.0069 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_1631 b8a6594d50d66a355fa6118b9145ba2c 99 Pfam PF01381 Helix-turn-helix 49 92 6.4E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFE_1631 b8a6594d50d66a355fa6118b9145ba2c 99 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 5 94 5.2E-37 T 12-10-2018 IPR014057 Uncharacterized protein HI1420 AFE_1631 b8a6594d50d66a355fa6118b9145ba2c 99 SUPERFAMILY SSF47413 33 92 5.35E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFE_3193 2dc4c9762fadae6607831f3e49a9cc75 894 Gene3D G3DSA:3.20.20.140 42 237 9.9E-14 T 12-10-2018 AFE_3193 2dc4c9762fadae6607831f3e49a9cc75 894 SUPERFAMILY SSF89550 54 256 2.16E-11 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFE_3193 2dc4c9762fadae6607831f3e49a9cc75 894 SUPERFAMILY SSF52540 285 835 3.13E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3193 2dc4c9762fadae6607831f3e49a9cc75 894 Gene3D G3DSA:3.40.50.300 282 524 1.3E-14 T 12-10-2018 AFE_0128 7f8786969f96009e97908302b33e5ef8 130 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 67 128 8.0E-9 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AFE_0128 7f8786969f96009e97908302b33e5ef8 130 Pfam PF01106 NifU-like domain 63 125 3.5E-17 T 12-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AFE_0128 7f8786969f96009e97908302b33e5ef8 130 Gene3D G3DSA:3.30.300.130 59 130 3.9E-18 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFE_0128 7f8786969f96009e97908302b33e5ef8 130 SUPERFAMILY SSF117916 61 126 6.1E-14 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFE_1491 3d96ebdc616b876ab9c80e7fa7ed0ad1 263 Pfam PF00005 ABC transporter 18 166 1.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFE_1491 3d96ebdc616b876ab9c80e7fa7ed0ad1 263 Gene3D G3DSA:3.40.50.300 3 254 7.4E-68 T 12-10-2018 AFE_1491 3d96ebdc616b876ab9c80e7fa7ed0ad1 263 SUPERFAMILY SSF52540 3 225 1.38E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1491 3d96ebdc616b876ab9c80e7fa7ed0ad1 263 SMART SM00382 27 215 2.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain AFE_1491 3d96ebdc616b876ab9c80e7fa7ed0ad1 263 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFE_0752 4b9b0c06707c494915967160a09af11a 141 Gene3D G3DSA:3.30.1130.10 3 129 3.5E-39 T 12-10-2018 AFE_0752 4b9b0c06707c494915967160a09af11a 141 Pfam PF14489 QueF-like protein 40 118 3.7E-29 T 12-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AFE_0752 4b9b0c06707c494915967160a09af11a 141 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 7 117 3.4E-50 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AFE_0752 4b9b0c06707c494915967160a09af11a 141 PIRSF PIRSF027377 2 124 1.1E-50 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AFE_0752 4b9b0c06707c494915967160a09af11a 141 SUPERFAMILY SSF55620 5 113 1.26E-24 T 12-10-2018 AFE_0752 4b9b0c06707c494915967160a09af11a 141 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 141 49.928 T 12-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 AFE_2002 a4ad5c2dfcfa075f3a0bd77e03b9bae0 113 SUPERFAMILY SSF88697 8 94 9.44E-13 T 12-10-2018 IPR015947 PUA-like superfamily AFE_2002 a4ad5c2dfcfa075f3a0bd77e03b9bae0 113 Gene3D G3DSA:3.10.590.10 2 104 1.6E-9 T 12-10-2018 AFE_2424 54a724b6a0624400f4386728779aa605 208 Gene3D G3DSA:1.20.1510.10 20 201 8.1E-15 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFE_2424 54a724b6a0624400f4386728779aa605 208 SUPERFAMILY SSF161111 19 201 5.36E-38 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFE_2424 54a724b6a0624400f4386728779aa605 208 Pfam PF01545 Cation efflux family 23 201 4.3E-21 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFE_2276 1b019fe2107083e2a2cab53e18c1c93b 199 Gene3D G3DSA:1.10.3210.10 10 196 1.3E-53 T 12-10-2018 AFE_2276 1b019fe2107083e2a2cab53e18c1c93b 199 SUPERFAMILY SSF109604 30 114 2.33E-7 T 12-10-2018 AFE_2276 1b019fe2107083e2a2cab53e18c1c93b 199 TIGRFAM TIGR03276 Phn-HD: phosphonate degradation operons associated HDIG domain protein 15 194 1.3E-76 T 12-10-2018 IPR017670 Phosphonate degradation operon associated HDIG domain protein AFE_2142 4ea2699c7d997316767cf74131109d7a 104 Gene3D G3DSA:1.10.20.30 7 54 5.1E-9 T 12-10-2018 AFE_2142 4ea2699c7d997316767cf74131109d7a 104 Pfam PF05164 Cell division protein ZapA 13 96 4.9E-17 T 12-10-2018 IPR007838 Cell division protein ZapA-like AFE_2142 4ea2699c7d997316767cf74131109d7a 104 SUPERFAMILY SSF102829 12 97 2.62E-16 T 12-10-2018 IPR036192 Cell division protein ZapA-like superfamily AFE_3095 401a6f8811accc02afc0a7a5dfa49e3d 245 Pfam PF03641 Possible lysine decarboxylase 93 222 6.2E-33 T 12-10-2018 IPR031100 LOG family AFE_3095 401a6f8811accc02afc0a7a5dfa49e3d 245 Gene3D G3DSA:3.40.50.450 28 227 2.9E-64 T 12-10-2018 AFE_3095 401a6f8811accc02afc0a7a5dfa49e3d 245 SUPERFAMILY SSF102405 24 224 8.09E-59 T 12-10-2018 AFE_3095 401a6f8811accc02afc0a7a5dfa49e3d 245 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 51 223 2.0E-44 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG AFE_2536 caa77191570578ff1ef80674f0d7c36a 276 SUPERFAMILY SSF52540 28 229 1.03E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2536 caa77191570578ff1ef80674f0d7c36a 276 Pfam PF07728 AAA domain (dynein-related subfamily) 40 174 9.3E-33 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFE_2536 caa77191570578ff1ef80674f0d7c36a 276 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 187 269 2.5E-26 T 12-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal AFE_2536 caa77191570578ff1ef80674f0d7c36a 276 Gene3D G3DSA:3.40.50.300 25 192 7.4E-30 T 12-10-2018 AFE_1072 600f5d7a796a53db09c11a042bff617c 242 Pfam PF08808 RES domain 77 218 2.0E-19 T 12-10-2018 IPR014914 RES domain AFE_1072 600f5d7a796a53db09c11a042bff617c 242 SMART SM00953 79 213 9.5E-12 T 12-10-2018 IPR014914 RES domain AFE_0476 b9cee7469bdf8beea583215d755e16e3 605 Pfam PF02272 DHHA1 domain 338 460 1.0E-10 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFE_0476 b9cee7469bdf8beea583215d755e16e3 605 Gene3D G3DSA:3.90.1640.30 59 340 6.5E-61 T 12-10-2018 AFE_0476 b9cee7469bdf8beea583215d755e16e3 605 Gene3D G3DSA:3.10.310.30 341 469 8.4E-21 T 12-10-2018 AFE_0476 b9cee7469bdf8beea583215d755e16e3 605 SUPERFAMILY SSF64182 57 474 2.62E-74 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily AFE_1251 d740744cd3165f69a659489e9dfed702 619 Pfam PF12696 TraM recognition site of TraD and TraG 403 502 2.1E-6 T 12-10-2018 IPR032689 TraD/TraG, TraM recognition site AFE_1251 d740744cd3165f69a659489e9dfed702 619 Gene3D G3DSA:3.40.50.300 335 559 2.9E-22 T 12-10-2018 AFE_1251 d740744cd3165f69a659489e9dfed702 619 SUPERFAMILY SSF52540 101 549 1.21E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_3293 bb4e9a765d060cf3c0c82ea1d6020665 479 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 4 477 1.8E-172 T 12-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AFE_3293 bb4e9a765d060cf3c0c82ea1d6020665 479 Pfam PF00483 Nucleotidyl transferase 6 287 6.4E-54 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFE_3293 bb4e9a765d060cf3c0c82ea1d6020665 479 SUPERFAMILY SSF53448 4 286 4.98E-68 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_3293 bb4e9a765d060cf3c0c82ea1d6020665 479 Pfam PF01050 Mannose-6-phosphate isomerase 323 473 3.0E-65 T 12-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AFE_3293 bb4e9a765d060cf3c0c82ea1d6020665 479 Gene3D G3DSA:3.90.550.10 4 357 1.0E-114 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_3293 bb4e9a765d060cf3c0c82ea1d6020665 479 SUPERFAMILY SSF51182 194 478 8.9E-81 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily AFE_3293 bb4e9a765d060cf3c0c82ea1d6020665 479 Gene3D G3DSA:2.60.120.10 358 463 1.6E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold AFE_0162 783ca36a25c7f77c69b8bedbfd93e735 80 Pfam PF13466 STAS domain 3 72 3.2E-13 T 12-10-2018 IPR002645 STAS domain AFE_0162 783ca36a25c7f77c69b8bedbfd93e735 80 Gene3D G3DSA:3.30.750.24 1 80 2.9E-9 T 12-10-2018 IPR036513 STAS domain superfamily AFE_0162 783ca36a25c7f77c69b8bedbfd93e735 80 SUPERFAMILY SSF52091 12 79 4.12E-9 T 12-10-2018 IPR036513 STAS domain superfamily AFE_1000 faddcca871f2a302556b2746e23fcb16 211 SMART SM01040 26 110 5.2E-35 T 12-10-2018 IPR003497 BRO N-terminal domain AFE_1000 faddcca871f2a302556b2746e23fcb16 211 Pfam PF02498 BRO family, N-terminal domain 26 110 3.1E-23 T 12-10-2018 IPR003497 BRO N-terminal domain AFE_0010 255ab47e5c3f94919cf3f6541d8a8c63 144 Pfam PF10387 Protein of unknown function (DUF2442) 30 98 5.5E-8 T 12-10-2018 IPR018841 Protein of unknown function DUF2442 AFE_0010 255ab47e5c3f94919cf3f6541d8a8c63 144 Gene3D G3DSA:3.30.2020.20 13 108 2.4E-28 T 12-10-2018 AFE_2374 84557e96b23d2e8181579f8665f87799 392 Pfam PF13166 AAA domain 150 356 6.8E-12 T 12-10-2018 IPR026866 Protein CR006, P-loop domain AFE_2374 84557e96b23d2e8181579f8665f87799 392 Gene3D G3DSA:3.40.50.300 59 240 4.4E-5 T 12-10-2018 AFE_0800 2fe921e3bb06c6135cdccea7df3002d7 282 PIRSF PIRSF028561 1 282 2.5E-101 T 12-10-2018 IPR014548 Predicted acyltransferase AFE_0800 2fe921e3bb06c6135cdccea7df3002d7 282 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 8 279 1.0E-13 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 AFE_3223 43f773f1e75765b009e6fd9f55a0e0fe 150 Gene3D G3DSA:3.40.50.360 31 149 1.4E-39 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFE_3223 43f773f1e75765b009e6fd9f55a0e0fe 150 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 35 148 4.5E-48 T 12-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 AFE_3223 43f773f1e75765b009e6fd9f55a0e0fe 150 SUPERFAMILY SSF52218 1 148 2.42E-34 T 12-10-2018 IPR029039 Flavoprotein-like superfamily AFE_2689 210381d4c6b01e14dcf11be997779f45 264 Gene3D G3DSA:3.30.1150.10 127 231 2.4E-9 T 12-10-2018 AFE_2689 210381d4c6b01e14dcf11be997779f45 264 SUPERFAMILY SSF74653 127 226 7.46E-10 T 12-10-2018 AFE_1902 cdfd13ba4de515e9d22d39548d4537e6 262 PIRSF PIRSF035875 3 259 1.7E-39 T 12-10-2018 IPR017039 Virulence factor BrkB AFE_1902 cdfd13ba4de515e9d22d39548d4537e6 262 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 8 254 7.9E-37 T 12-10-2018 IPR017039 Virulence factor BrkB AFE_1902 cdfd13ba4de515e9d22d39548d4537e6 262 Pfam PF03631 Virulence factor BrkB 14 255 1.5E-44 T 12-10-2018 IPR017039 Virulence factor BrkB AFE_1776 02f31fd83a242d6b37b9b43892275220 320 SUPERFAMILY SSF53448 4 246 1.03E-34 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_1776 02f31fd83a242d6b37b9b43892275220 320 Gene3D G3DSA:3.90.550.10 1 194 3.9E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFE_1776 02f31fd83a242d6b37b9b43892275220 320 Pfam PF00535 Glycosyl transferase family 2 4 166 5.8E-29 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFE_1845 19c011a1427051542a371d6c3014b415 79 Pfam PF11160 Protein of unknown function (DUF2945) 12 70 8.4E-23 T 12-10-2018 IPR021331 Protein of unknown function DUF2945 AFE_0553 dc4addd2f7c854027a0d73dbf39b039d 191 Pfam PF00578 AhpC/TSA family 10 131 1.7E-16 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFE_0553 dc4addd2f7c854027a0d73dbf39b039d 191 Gene3D G3DSA:3.40.30.10 3 191 5.4E-48 T 12-10-2018 AFE_0553 dc4addd2f7c854027a0d73dbf39b039d 191 SUPERFAMILY SSF52833 7 187 2.42E-43 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_1790 32c178205da9fdff02dc29f329a46864 273 Pfam PF02616 Segregation and condensation protein ScpA 53 128 1.5E-14 T 12-10-2018 IPR003768 Segregation and condensation protein A AFE_1732 395cd850b8c663bd8c886b9484e2b3fb 76 SUPERFAMILY SSF54786 4 75 2.63E-5 T 12-10-2018 AFE_1732 395cd850b8c663bd8c886b9484e2b3fb 76 Gene3D G3DSA:3.30.920.30 6 76 5.7E-5 T 12-10-2018 IPR038570 HicA superfamily AFE_0237 572fbb4eb442b9e1c71f99f1c6441ae2 417 SUPERFAMILY SSF53756 89 400 2.43E-11 T 12-10-2018 AFE_0237 572fbb4eb442b9e1c71f99f1c6441ae2 417 Gene3D G3DSA:3.40.50.11720 38 207 1.3E-50 T 12-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 AFE_0237 572fbb4eb442b9e1c71f99f1c6441ae2 417 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 34 208 9.0E-65 T 12-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 AFE_0237 572fbb4eb442b9e1c71f99f1c6441ae2 417 Gene3D G3DSA:3.40.50.2000 214 400 9.1E-61 T 12-10-2018 AFE_2214 c93ef434ae571307d176b27c2dda132a 188 Pfam PF05656 Protein of unknown function (DUF805) 14 172 1.6E-26 T 12-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 AFE_2550 180b1225d81795b08dc88eb6fde9f70f 303 Pfam PF02754 Cysteine-rich domain 152 246 1.8E-10 T 12-10-2018 IPR004017 Cysteine-rich domain AFE_2550 180b1225d81795b08dc88eb6fde9f70f 303 Pfam PF02754 Cysteine-rich domain 4 87 8.9E-15 T 12-10-2018 IPR004017 Cysteine-rich domain AFE_1681 6e278ebb893fcada756c90c136e61d22 92 Gene3D G3DSA:3.30.1360.20 12 90 2.6E-26 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFE_1681 6e278ebb893fcada756c90c136e61d22 92 SUPERFAMILY SSF55248 19 87 1.57E-9 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 AFE_2700 ac710aaca8e9a9178b85657b8e1e0d05 312 Gene3D G3DSA:1.20.81.30 159 274 1.2E-5 T 12-10-2018 AFE_2700 ac710aaca8e9a9178b85657b8e1e0d05 312 Pfam PF00482 Type II secretion system (T2SS), protein F 168 296 1.7E-16 T 12-10-2018 IPR018076 Type II secretion system F domain AFE_0707 0fa9288887e3a278460aec8d12a6f650 326 SUPERFAMILY SSF48452 187 303 6.07E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0707 0fa9288887e3a278460aec8d12a6f650 326 Gene3D G3DSA:1.25.40.10 43 177 7.8E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0707 0fa9288887e3a278460aec8d12a6f650 326 Gene3D G3DSA:1.25.40.10 180 317 6.5E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0707 0fa9288887e3a278460aec8d12a6f650 326 SUPERFAMILY SSF48452 55 219 1.4E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFE_0363 8b240c886c60a6c28977accd6c81e7a9 125 Gene3D G3DSA:3.40.1260.10 1 123 1.6E-32 T 12-10-2018 IPR027396 DsrEFH-like AFE_0363 8b240c886c60a6c28977accd6c81e7a9 125 Pfam PF13686 DsrE/DsrF/DrsH-like family 65 120 3.0E-9 T 12-10-2018 IPR032836 DsrE2-like family AFE_0363 8b240c886c60a6c28977accd6c81e7a9 125 SUPERFAMILY SSF75169 8 118 1.51E-15 T 12-10-2018 IPR027396 DsrEFH-like AFE_0131 8e344fd88210b0a9a594b3eee63c9482 311 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 68 296 6.3E-32 T 12-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related AFE_2151 715c991877290d919859b11ae738f4ce 225 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 37 196 2.0E-33 T 12-10-2018 AFE_2590 18c925223fcf8f264a47ddf8a118f94a 111 SUPERFAMILY SSF52833 10 90 1.19E-12 T 12-10-2018 IPR036249 Thioredoxin-like superfamily AFE_2590 18c925223fcf8f264a47ddf8a118f94a 111 Pfam PF00085 Thioredoxin 8 98 1.2E-6 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFE_2590 18c925223fcf8f264a47ddf8a118f94a 111 Gene3D G3DSA:3.40.30.10 2 103 3.4E-8 T 12-10-2018 AFE_2515 9c92994b49fbdc7768c9560c3968dc69 158 Pfam PF00583 Acetyltransferase (GNAT) family 37 120 7.4E-12 T 12-10-2018 IPR000182 GNAT domain AFE_2515 9c92994b49fbdc7768c9560c3968dc69 158 SUPERFAMILY SSF55729 1 142 7.03E-32 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_2515 9c92994b49fbdc7768c9560c3968dc69 158 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 10 143 6.9E-32 T 12-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 AFE_2515 9c92994b49fbdc7768c9560c3968dc69 158 Gene3D G3DSA:3.40.630.30 2 156 4.9E-41 T 12-10-2018 AFE_0687 f50b54645db673f4832483332c7d1469 519 Pfam PF13289 SIR2-like domain 104 252 8.1E-27 T 12-10-2018 IPR039444 SIR2-like domain AFE_0687 f50b54645db673f4832483332c7d1469 519 SUPERFAMILY SSF52467 10 210 3.18E-11 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFE_0571 b452425456dfb6e766200ea39d51955e 347 Pfam PF01594 AI-2E family transporter 6 331 1.5E-57 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like AFE_0996 ff3331a36107c109eb5060897163e9bd 119 Pfam PF12728 Helix-turn-helix domain 5 51 4.2E-10 T 12-10-2018 AFE_1915 ae0c59c7d8968483055eb02591d5b8fc 118 Gene3D G3DSA:2.40.10.220 5 116 3.4E-28 T 12-10-2018 AFE_1915 ae0c59c7d8968483055eb02591d5b8fc 118 Pfam PF07238 PilZ domain 14 103 1.3E-9 T 12-10-2018 IPR009875 PilZ domain GO:0035438 AFE_1708 b72eb7cc7fe09a87705805e6461c27f5 115 Pfam PF05717 IS66 Orf2 like protein 8 102 8.3E-38 T 12-10-2018 IPR008878 Transposase IS66, Orf2 AFE_3172 6b51c998d71e17269d813ac92038025d 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 122 9.4E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFE_3172 6b51c998d71e17269d813ac92038025d 132 Gene3D G3DSA:3.10.180.10 7 130 5.9E-40 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFE_3172 6b51c998d71e17269d813ac92038025d 132 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 12-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 AFE_3172 6b51c998d71e17269d813ac92038025d 132 SUPERFAMILY SSF54593 1 125 2.75E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFE_1104 f9a15f1861b3192275e4b0092d0b3116 425 Gene3D G3DSA:2.60.120.260 267 408 6.0E-8 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily AFE_1603 8c2782c867bc6173c46bcf0d02417476 378 Pfam PF12698 ABC-2 family transporter protein 26 370 2.4E-43 T 12-10-2018 AFE_1437 8d34af20e45db1be9f47f8ceff635169 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 307 4.0E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFE_1437 8d34af20e45db1be9f47f8ceff635169 325 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 23 315 6.2E-92 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 AFE_1437 8d34af20e45db1be9f47f8ceff635169 325 Gene3D G3DSA:1.10.3720.10 76 319 9.0E-31 T 12-10-2018 IPR035906 MetI-like superfamily AFE_1437 8d34af20e45db1be9f47f8ceff635169 325 SUPERFAMILY SSF161098 32 309 2.43E-33 T 12-10-2018 IPR035906 MetI-like superfamily AFE_2386 a30538d275871b24759ec7744469dc20 248 Pfam PF00899 ThiF family 11 238 6.3E-35 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFE_2386 a30538d275871b24759ec7744469dc20 248 Gene3D G3DSA:3.40.50.720 1 246 7.3E-72 T 12-10-2018 AFE_2386 a30538d275871b24759ec7744469dc20 248 SUPERFAMILY SSF69572 5 243 2.62E-54 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AFE_3207 b9a14ccb0a0496b61a007f56d8c066fd 159 SUPERFAMILY SSF81573 66 124 2.35E-13 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily AFE_3207 b9a14ccb0a0496b61a007f56d8c066fd 159 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 13 159 8.7E-58 T 12-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 AFE_3207 b9a14ccb0a0496b61a007f56d8c066fd 159 Gene3D G3DSA:1.20.5.620 65 125 2.7E-15 T 12-10-2018 AFE_3207 b9a14ccb0a0496b61a007f56d8c066fd 159 Pfam PF00430 ATP synthase B/B' CF(0) 9 139 4.3E-41 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFE_3207 b9a14ccb0a0496b61a007f56d8c066fd 159 Hamap MF_01398 ATP synthase subunit b [atpF]. 5 141 12.851 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFE_1545 b721391e61af7d86cdfe305314fd47d5 68 SUPERFAMILY SSF50331 1 67 1.25E-18 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFE_1545 b721391e61af7d86cdfe305314fd47d5 68 Gene3D G3DSA:2.40.50.100 1 66 7.7E-22 T 12-10-2018 AFE_1545 b721391e61af7d86cdfe305314fd47d5 68 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 66 9.9E-20 T 12-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 AFE_1545 b721391e61af7d86cdfe305314fd47d5 68 Pfam PF03459 TOBE domain 3 64 4.9E-18 T 12-10-2018 IPR005116 Transport-associated OB, type 1 AFE_3270 4d1eef140e1da975039be081bd2b6d5d 519 SUPERFAMILY SSF55874 25 116 2.55E-10 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_3270 4d1eef140e1da975039be081bd2b6d5d 519 Gene3D G3DSA:3.30.565.10 9 177 1.2E-5 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFE_2281 4b16d50b5db2d20d6e97ee2a249314a3 274 Pfam PF06007 Phosphonate metabolism protein PhnJ 5 273 5.3E-137 T 12-10-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFE_2281 4b16d50b5db2d20d6e97ee2a249314a3 274 PIRSF PIRSF011468 1 274 2.9E-141 T 12-10-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFE_2736 6e637e3ac23bcac705daeceb33179d22 219 SUPERFAMILY SSF53335 27 204 4.55E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_2736 6e637e3ac23bcac705daeceb33179d22 219 PIRSF PIRSF005461 1 214 3.0E-70 T 12-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 AFE_2736 6e637e3ac23bcac705daeceb33179d22 219 Pfam PF01728 FtsJ-like methyltransferase 28 203 5.6E-48 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 AFE_2736 6e637e3ac23bcac705daeceb33179d22 219 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 204 27.773 T 12-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 AFE_2736 6e637e3ac23bcac705daeceb33179d22 219 Gene3D G3DSA:3.40.50.150 24 210 2.4E-53 T 12-10-2018 AFE_0594 6c33f5fe8a2302a077acc68225919cfc 200 Gene3D G3DSA:3.40.50.150 11 185 1.3E-14 T 12-10-2018 AFE_0594 6c33f5fe8a2302a077acc68225919cfc 200 SUPERFAMILY SSF53335 31 177 4.01E-19 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0594 6c33f5fe8a2302a077acc68225919cfc 200 Pfam PF13649 Methyltransferase domain 50 138 6.5E-7 T 12-10-2018 AFE_1254 80c704270798413f793558171257bf07 835 SMART SM00471 168 440 0.0071 T 12-10-2018 IPR003607 HD/PDEase domain AFE_2149 18f529b3b1fab127e91244cb8a6474bd 660 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 80 105 7.4E-10 T 12-10-2018 AFE_2149 18f529b3b1fab127e91244cb8a6474bd 660 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 222 243 7.4E-10 T 12-10-2018 AFE_2149 18f529b3b1fab127e91244cb8a6474bd 660 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 439 458 7.4E-10 T 12-10-2018 AFE_2149 18f529b3b1fab127e91244cb8a6474bd 660 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 7.4E-10 T 12-10-2018 AFE_2149 18f529b3b1fab127e91244cb8a6474bd 660 Pfam PF00361 Proton-conducting membrane transporter 133 418 4.3E-52 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2975 88fed753a50917759e84850dc831b914 390 Gene3D G3DSA:3.30.1950.10 86 176 3.4E-66 T 12-10-2018 AFE_2975 88fed753a50917759e84850dc831b914 390 Pfam PF02563 Polysaccharide biosynthesis/export protein 79 172 4.7E-18 T 12-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 AFE_2975 88fed753a50917759e84850dc831b914 390 Pfam PF10531 SLBB domain 180 229 0.0057 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2975 88fed753a50917759e84850dc831b914 390 Gene3D G3DSA:3.10.560.10 66 258 3.4E-66 T 12-10-2018 AFE_2975 88fed753a50917759e84850dc831b914 390 Gene3D G3DSA:3.10.560.10 60 358 3.4E-66 T 12-10-2018 AFE_2269 f5b14f9eb2b44d2819620a28615fc364 133 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 130 1.3E-27 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 AFE_2269 f5b14f9eb2b44d2819620a28615fc364 133 Gene3D G3DSA:3.30.420.270 60 127 1.3E-9 T 12-10-2018 AFE_1535 b5c94b73574de1a7cdb4b7ec52172da7 97 Pfam PF04319 NifZ domain 13 84 6.3E-28 T 12-10-2018 IPR007415 Nitrogenase MoFe maturation protein, NifZ GO:0009399 AFE_3005 3cc703e35592caf10643e9708ee42318 160 Gene3D G3DSA:3.40.630.30 9 153 9.9E-26 T 12-10-2018 AFE_3005 3cc703e35592caf10643e9708ee42318 160 SUPERFAMILY SSF55729 33 145 3.04E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_3005 3cc703e35592caf10643e9708ee42318 160 Pfam PF00583 Acetyltransferase (GNAT) family 53 140 2.7E-14 T 12-10-2018 IPR000182 GNAT domain AFE_0269 97a9755fa07d41f248e4fe233b4cb735 229 Pfam PF00753 Metallo-beta-lactamase superfamily 13 171 2.0E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_0269 97a9755fa07d41f248e4fe233b4cb735 229 SUPERFAMILY SSF56281 7 225 3.92E-54 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_0269 97a9755fa07d41f248e4fe233b4cb735 229 SMART SM00849 12 171 5.8E-32 T 12-10-2018 IPR001279 Metallo-beta-lactamase AFE_0269 97a9755fa07d41f248e4fe233b4cb735 229 Gene3D G3DSA:3.60.15.10 1 229 3.9E-81 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_0130 d026060a3d910260d5f24c23f5244d50 451 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 183 389 7.4E-38 T 12-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 AFE_0130 d026060a3d910260d5f24c23f5244d50 451 Gene3D G3DSA:3.40.50.12710 95 451 2.3E-99 T 12-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 AFE_0130 d026060a3d910260d5f24c23f5244d50 451 SUPERFAMILY SSF53335 111 448 4.52E-77 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0150 f10f4378827893371cd5ba4b4bf777c8 264 Gene3D G3DSA:3.40.50.150 24 260 4.2E-42 T 12-10-2018 AFE_0150 f10f4378827893371cd5ba4b4bf777c8 264 SUPERFAMILY SSF53335 41 226 8.63E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0150 f10f4378827893371cd5ba4b4bf777c8 264 Pfam PF01564 Spermine/spermidine synthase domain 56 195 1.2E-6 T 12-10-2018 AFE_0781 1b4a072c697dd3791f90cbfc860f9fe5 66 Pfam PF13318 Protein of unknown function (DUF4089) 24 64 2.0E-10 T 12-10-2018 IPR025148 Protein of unknown function DUF4089 AFE_3090 decbaecde728a8fa203509cd185acd01 397 Gene3D G3DSA:1.20.1250.20 207 392 4.2E-9 T 12-10-2018 AFE_3090 decbaecde728a8fa203509cd185acd01 397 Gene3D G3DSA:1.20.1250.20 2 196 6.3E-15 T 12-10-2018 AFE_3090 decbaecde728a8fa203509cd185acd01 397 SUPERFAMILY SSF103473 10 389 1.57E-33 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_3090 decbaecde728a8fa203509cd185acd01 397 Pfam PF07690 Major Facilitator Superfamily 14 353 4.0E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_0199 623509e769f1ae19e767396cbc772bd1 285 Gene3D G3DSA:1.10.620.20 7 232 4.8E-10 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 AFE_0199 623509e769f1ae19e767396cbc772bd1 285 SUPERFAMILY SSF47240 6 270 1.21E-41 T 12-10-2018 IPR009078 Ferritin-like superfamily AFE_2905 1b0f26b50ec602af526ebc0b67d0d186 487 SUPERFAMILY SSF56059 30 471 9.47E-62 T 12-10-2018 AFE_2905 1b0f26b50ec602af526ebc0b67d0d186 487 PIRSF PIRSF005522 1 483 5.8E-215 T 12-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 AFE_2905 1b0f26b50ec602af526ebc0b67d0d186 487 Gene3D G3DSA:3.40.50.11290 218 316 1.6E-36 T 12-10-2018 AFE_2905 1b0f26b50ec602af526ebc0b67d0d186 487 Pfam PF14403 Circularly permuted ATP-grasp type 2 80 456 1.9E-158 T 12-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 AFE_2905 1b0f26b50ec602af526ebc0b67d0d186 487 Gene3D G3DSA:3.30.1490.270 353 413 1.0E-25 T 12-10-2018 AFE_1073 c9541f2767719831a568ab499f639d61 313 SMART SM01040 13 108 1.9E-36 T 12-10-2018 IPR003497 BRO N-terminal domain AFE_1073 c9541f2767719831a568ab499f639d61 313 Pfam PF02498 BRO family, N-terminal domain 14 108 6.5E-24 T 12-10-2018 IPR003497 BRO N-terminal domain AFE_2930 545fc0ce97ea3eb5f860a2e2446d9e2c 193 Pfam PF06736 Protein of unknown function (DUF1211) 5 89 5.3E-30 T 12-10-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 AFE_2150 64ff916b098227125eead19e5c62268e 313 Pfam PF00146 NADH dehydrogenase 11 303 5.5E-34 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2199 92af3361ddc4d5355491a4a06cad0397 357 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 354 2.3E-59 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 AFE_2199 92af3361ddc4d5355491a4a06cad0397 357 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 353 3.9E-96 T 12-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 AFE_1636 b61f847d2b6acf82e0033b804927ffa4 128 Pfam PF04956 TrbC/VIRB2 family 7 97 2.4E-8 T 12-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 AFE_3299 782a6f9ef1f5f02ea3d00fbbcc98ee15 262 SUPERFAMILY SSF69618 8 251 3.4E-66 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3299 782a6f9ef1f5f02ea3d00fbbcc98ee15 262 Pfam PF02602 Uroporphyrinogen-III synthase HemD 22 249 1.5E-55 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFE_3299 782a6f9ef1f5f02ea3d00fbbcc98ee15 262 Gene3D G3DSA:3.40.50.10090 40 172 3.8E-67 T 12-10-2018 AFE_3299 782a6f9ef1f5f02ea3d00fbbcc98ee15 262 Gene3D G3DSA:3.40.50.10090 11 246 3.8E-67 T 12-10-2018 AFE_0359 2f4a4e73b4661a4fc25d936685cd0c5f 121 Gene3D G3DSA:1.10.3830.10 2 118 1.2E-32 T 12-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 AFE_0359 2f4a4e73b4661a4fc25d936685cd0c5f 121 Pfam PF01219 Prokaryotic diacylglycerol kinase 13 112 2.3E-29 T 12-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 AFE_2119 8ea466db8f807719d0f85aa17b604f57 291 Pfam PF04794 YdjC-like protein 8 276 3.5E-60 T 12-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like AFE_2119 8ea466db8f807719d0f85aa17b604f57 291 Gene3D G3DSA:3.20.20.370 6 289 1.2E-58 T 12-10-2018 AFE_2119 8ea466db8f807719d0f85aa17b604f57 291 TIGRFAM TIGR03473 HpnK: hopanoid biosynthesis associated protein HpnK 7 289 1.0E-138 T 12-10-2018 IPR017836 Hopanoid biosynthesis associated protein HpnK AFE_2119 8ea466db8f807719d0f85aa17b604f57 291 SUPERFAMILY SSF88713 7 288 2.05E-71 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFE_0378 6e1d4115fa5c1ce70b7b27e03be1c9e6 356 SUPERFAMILY SSF56935 29 353 7.32E-42 T 12-10-2018 AFE_0378 6e1d4115fa5c1ce70b7b27e03be1c9e6 356 Gene3D G3DSA:2.40.160.60 30 356 1.3E-42 T 12-10-2018 AFE_0378 6e1d4115fa5c1ce70b7b27e03be1c9e6 356 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 212 350 2.2E-12 T 12-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) AFE_0378 6e1d4115fa5c1ce70b7b27e03be1c9e6 356 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 15 167 1.3E-15 T 12-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) AFE_1560 03f9fc55f8226c52a346a92011e8877f 112 ProDom PD394905 PM1122 UNCHARACTERIZED 4 86 3.0E-10 T 12-10-2018 AFE_1591 8fa7860e1a4fb9490d8ef2683d605e2c 186 Pfam PF01553 Acyltransferase 4 98 2.9E-5 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFE_1591 8fa7860e1a4fb9490d8ef2683d605e2c 186 SUPERFAMILY SSF69593 3 118 1.57E-5 T 12-10-2018 AFE_1591 8fa7860e1a4fb9490d8ef2683d605e2c 186 SMART SM00563 5 126 2.5E-4 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFE_0055 d94f2a402dfd76eeb3a8338dfd650153 85 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 1.3E-21 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFE_0055 d94f2a402dfd76eeb3a8338dfd650153 85 Pfam PF09723 Zinc ribbon domain 1 40 1.1E-15 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFE_0055 d94f2a402dfd76eeb3a8338dfd650153 85 SMART SM00834 1 42 7.5E-18 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain AFE_0064 456a1a4de6c5adf56c9a8438849947cf 233 TIGRFAM TIGR02796 tolQ: protein TolQ 15 226 1.2E-86 T 12-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 AFE_0064 456a1a4de6c5adf56c9a8438849947cf 233 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 13 231 40.519 T 12-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 AFE_0064 456a1a4de6c5adf56c9a8438849947cf 233 Pfam PF01618 MotA/TolQ/ExbB proton channel family 89 214 1.5E-37 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel AFE_1058 334175a9f5c1effd9b0eed9d50ec9453 408 Pfam PF07282 Putative transposase DNA-binding domain 318 386 1.0E-20 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFE_1058 334175a9f5c1effd9b0eed9d50ec9453 408 Pfam PF01385 Probable transposase 176 289 8.1E-16 T 12-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFE_1058 334175a9f5c1effd9b0eed9d50ec9453 408 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 260 345 3.8E-10 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFE_1058 334175a9f5c1effd9b0eed9d50ec9453 408 Pfam PF12323 Helix-turn-helix domain 1 42 9.0E-16 T 12-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain AFE_2864 4a280791bf90de3e292ee2134409613a 369 Pfam PF12698 ABC-2 family transporter protein 32 361 4.0E-38 T 12-10-2018 AFE_3003 d80020bb9c2b6ee33a863520a478488c 215 Pfam PF01618 MotA/TolQ/ExbB proton channel family 73 198 9.4E-27 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel AFE_2576 49e43d8cafa93ce2b283dde4811f3697 188 Pfam PF03029 Conserved hypothetical ATP binding protein 30 132 6.2E-10 T 12-10-2018 IPR004130 GPN-loop GTPase AFE_2576 49e43d8cafa93ce2b283dde4811f3697 188 Gene3D G3DSA:3.40.50.300 4 181 1.3E-18 T 12-10-2018 AFE_2576 49e43d8cafa93ce2b283dde4811f3697 188 SUPERFAMILY SSF52540 6 180 1.55E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_2576 49e43d8cafa93ce2b283dde4811f3697 188 PRINTS PR00449 Transforming protein P21 ras signature 158 180 8.0E-8 T 12-10-2018 AFE_2576 49e43d8cafa93ce2b283dde4811f3697 188 PRINTS PR00449 Transforming protein P21 ras signature 5 26 8.0E-8 T 12-10-2018 AFE_2576 49e43d8cafa93ce2b283dde4811f3697 188 PRINTS PR00449 Transforming protein P21 ras signature 55 77 8.0E-8 T 12-10-2018 AFE_2576 49e43d8cafa93ce2b283dde4811f3697 188 PRINTS PR00449 Transforming protein P21 ras signature 116 129 8.0E-8 T 12-10-2018 AFE_0771 c6dea7a58101d048f2e0dbca29b9b9b3 474 PIRSF PIRSF002744 2 453 3.3E-47 T 12-10-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 AFE_0771 c6dea7a58101d048f2e0dbca29b9b9b3 474 Gene3D G3DSA:1.10.4160.10 4 367 2.7E-15 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily AFE_0771 c6dea7a58101d048f2e0dbca29b9b9b3 474 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 11 368 1.7E-14 T 12-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 AFE_2380 32bdf55f39569317e0c3b1752638b726 204 Pfam PF04326 Putative DNA-binding domain 19 64 2.7E-9 T 12-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 AFE_2380 32bdf55f39569317e0c3b1752638b726 204 Gene3D G3DSA:3.30.950.30 6 74 5.3E-10 T 12-10-2018 IPR038461 Schlafen, AAA domain superfamily AFE_0018 fc1defc6501f8f4c953bf2cf2968a0bc 349 SMART SM00257 37 85 6.1E-6 T 12-10-2018 IPR018392 LysM domain AFE_0018 fc1defc6501f8f4c953bf2cf2968a0bc 349 Pfam PF01476 LysM domain 38 84 1.5E-11 T 12-10-2018 IPR018392 LysM domain AFE_0018 fc1defc6501f8f4c953bf2cf2968a0bc 349 SUPERFAMILY SSF54106 37 84 1.83E-7 T 12-10-2018 AFE_0018 fc1defc6501f8f4c953bf2cf2968a0bc 349 Gene3D G3DSA:3.10.350.10 36 83 1.9E-13 T 12-10-2018 IPR036779 LysM domain superfamily AFE_0626 09cf08be0f8b4df945862496e5f88003 207 Pfam PF00694 Aconitase C-terminal domain 1 125 6.7E-37 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 AFE_0626 09cf08be0f8b4df945862496e5f88003 207 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 204 41.423 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AFE_0626 09cf08be0f8b4df945862496e5f88003 207 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 190 2.7E-78 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AFE_0626 09cf08be0f8b4df945862496e5f88003 207 Gene3D G3DSA:3.20.19.10 1 182 3.0E-73 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 AFE_0626 09cf08be0f8b4df945862496e5f88003 207 SUPERFAMILY SSF52016 1 199 8.63E-59 T 12-10-2018 AFE_2530 0a775838e9077ff5749bea43a953f2fa 250 SUPERFAMILY SSF52317 4 200 8.35E-20 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_2530 0a775838e9077ff5749bea43a953f2fa 250 Gene3D G3DSA:3.40.50.880 1 236 5.4E-29 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like AFE_1469 9501ab182965f52ade2cbe6f5b2fc3de 469 Pfam PF02562 PhoH-like protein 256 459 9.9E-53 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 AFE_1469 9501ab182965f52ade2cbe6f5b2fc3de 469 Gene3D G3DSA:3.40.50.1010 10 160 5.6E-24 T 12-10-2018 AFE_1469 9501ab182965f52ade2cbe6f5b2fc3de 469 SUPERFAMILY SSF52540 132 449 1.19E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFE_1469 9501ab182965f52ade2cbe6f5b2fc3de 469 SMART SM00670 15 144 2.8E-12 T 12-10-2018 IPR002716 PIN domain AFE_1469 9501ab182965f52ade2cbe6f5b2fc3de 469 Pfam PF13638 PIN domain 17 157 8.0E-40 T 12-10-2018 IPR002716 PIN domain AFE_1469 9501ab182965f52ade2cbe6f5b2fc3de 469 SUPERFAMILY SSF88723 16 158 1.11E-14 T 12-10-2018 IPR029060 PIN-like domain superfamily AFE_1469 9501ab182965f52ade2cbe6f5b2fc3de 469 Gene3D G3DSA:3.40.50.300 255 467 1.0E-64 T 12-10-2018 AFE_1649 6e88e55279b5797a1478a87bfab50781 251 SUPERFAMILY SSF53098 133 244 5.06E-17 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily AFE_1649 6e88e55279b5797a1478a87bfab50781 251 Gene3D G3DSA:3.30.420.10 135 249 2.6E-9 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFE_1649 6e88e55279b5797a1478a87bfab50781 251 Pfam PF00665 Integrase core domain 133 242 4.7E-14 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFE_1477 9ebe4bf7a6f12fe193fcc77de4b4fcb5 95 Gene3D G3DSA:3.30.70.20 6 89 4.8E-13 T 12-10-2018 AFE_1477 9ebe4bf7a6f12fe193fcc77de4b4fcb5 95 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 14 89 1.5E-7 T 12-10-2018 AFE_1477 9ebe4bf7a6f12fe193fcc77de4b4fcb5 95 SUPERFAMILY SSF54862 22 93 2.97E-12 T 12-10-2018 AFE_1477 9ebe4bf7a6f12fe193fcc77de4b4fcb5 95 PIRSF PIRSF036548 1 95 3.3E-39 T 12-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 AFE_2231 089ed5ca6f9d00c7d97a4adb719fc395 30 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 2.7E-7 T 12-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 AFE_2231 089ed5ca6f9d00c7d97a4adb719fc395 30 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 8.1E-5 T 12-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 AFE_2701 19d230893319db19787f05358c36cac4 313 Pfam PF00482 Type II secretion system (T2SS), protein F 146 272 9.7E-15 T 12-10-2018 IPR018076 Type II secretion system F domain AFE_1832 1540c0242881112d20c776065a303a3b 260 Gene3D G3DSA:2.60.120.620 4 229 6.7E-24 T 12-10-2018 AFE_0077 315c8524d3e3e6090c6b9edf0cff5998 353 Gene3D G3DSA:3.40.50.150 135 307 2.1E-36 T 12-10-2018 AFE_0077 315c8524d3e3e6090c6b9edf0cff5998 353 SUPERFAMILY SSF53335 130 298 4.22E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0077 315c8524d3e3e6090c6b9edf0cff5998 353 Pfam PF13489 Methyltransferase domain 136 285 3.5E-24 T 12-10-2018 AFE_2179 9e5e3d789c3d96041e7a69e122e64df4 344 Pfam PF03916 Polysulphide reductase, NrfD 16 321 6.7E-24 T 12-10-2018 IPR005614 NrfD family AFE_2951 be5987d684120f2175a481c56de4abff 143 Pfam PF14346 Domain of unknown function (DUF4398) 19 121 6.5E-6 T 12-10-2018 IPR025511 Domain of unknown function DUF4398 AFE_2792 010271b8b601dfc707b012f6e22ee5c9 73 Pfam PF16277 Domain of unknown function (DUF4926) 4 60 2.4E-19 T 12-10-2018 IPR032568 Protein of unknown function DUF4926 AFE_3148 a8edb4a5436d24a23924aa84e8258df2 184 Gene3D G3DSA:1.20.120.80 18 184 4.4E-10 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_3148 a8edb4a5436d24a23924aa84e8258df2 184 SUPERFAMILY SSF81452 22 183 3.01E-5 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFE_2623 13fa2e52e577941436367308feb21566 341 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 216 229 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2623 13fa2e52e577941436367308feb21566 341 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 57 72 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2623 13fa2e52e577941436367308feb21566 341 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 11 335 25.706 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2623 13fa2e52e577941436367308feb21566 341 Pfam PF00146 NADH dehydrogenase 17 328 1.7E-128 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFE_2704 4d35b565b46abfeb19465a916e79c81a 478 Pfam PF00263 Bacterial type II and III secretion system protein 269 433 4.9E-47 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 AFE_2704 4d35b565b46abfeb19465a916e79c81a 478 Pfam PF13629 Pilus formation protein N terminal region 46 118 2.7E-20 T 12-10-2018 IPR032789 Pilus formation protein, N-terminal AFE_2704 4d35b565b46abfeb19465a916e79c81a 478 PRINTS PR00811 Bacterial general secretion pathway protein D signature 264 288 5.0E-12 T 12-10-2018 IPR001775 GspD/PilQ family AFE_2704 4d35b565b46abfeb19465a916e79c81a 478 PRINTS PR00811 Bacterial general secretion pathway protein D signature 303 313 5.0E-12 T 12-10-2018 IPR001775 GspD/PilQ family AFE_2704 4d35b565b46abfeb19465a916e79c81a 478 PRINTS PR00811 Bacterial general secretion pathway protein D signature 420 434 5.0E-12 T 12-10-2018 IPR001775 GspD/PilQ family AFE_2704 4d35b565b46abfeb19465a916e79c81a 478 PRINTS PR00811 Bacterial general secretion pathway protein D signature 397 415 5.0E-12 T 12-10-2018 IPR001775 GspD/PilQ family AFE_2719 4029c1e86f04376fe36eabb5fe312c1f 68 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 21 52 3.0E-8 T 12-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 AFE_0304 85dc1030df7b9bb88e6e00ae44e05cd8 117 Pfam PF06305 Lipopolysaccharide assembly protein A domain 19 81 4.0E-11 T 12-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 AFE_2620 b701e8ed87806674300c18ad90a3021a 105 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 6 105 21.164 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 AFE_2620 b701e8ed87806674300c18ad90a3021a 105 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 11 100 1.7E-23 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like AFE_0053 51d46b8867b1de352976f112c367dfa6 344 Pfam PF04143 Sulphur transport 15 312 5.0E-30 T 12-10-2018 IPR007272 Sulphur transport domain AFE_0794 1ed42c998a23b8d3ed32b76503437cd3 166 SUPERFAMILY SSF54637 6 137 4.22E-8 T 12-10-2018 IPR029069 HotDog domain superfamily AFE_0794 1ed42c998a23b8d3ed32b76503437cd3 166 Gene3D G3DSA:3.10.129.10 1 145 6.1E-6 T 12-10-2018 AFE_2070 ca06e611dd4733c7925eec0f458b30c1 205 Gene3D G3DSA:3.20.20.70 3 205 3.8E-68 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFE_2070 ca06e611dd4733c7925eec0f458b30c1 205 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 6 200 1.4E-43 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AFE_2070 ca06e611dd4733c7925eec0f458b30c1 205 SUPERFAMILY SSF51366 5 202 1.18E-59 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFE_2070 ca06e611dd4733c7925eec0f458b30c1 205 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 4 205 42.596 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AFE_0798 fb862a3327adb896626268a44a260cae 784 Pfam PF03176 MMPL family 646 778 4.6E-6 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFE_0798 fb862a3327adb896626268a44a260cae 784 Pfam PF03176 MMPL family 176 392 6.5E-9 T 12-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFE_0798 fb862a3327adb896626268a44a260cae 784 SUPERFAMILY SSF82866 609 775 1.96E-20 T 12-10-2018 AFE_0798 fb862a3327adb896626268a44a260cae 784 SUPERFAMILY SSF82866 226 392 1.31E-15 T 12-10-2018 AFE_2004 86b0e02da575446b345c1c6e1dfff7fb 142 Pfam PF00583 Acetyltransferase (GNAT) family 38 127 3.5E-15 T 12-10-2018 IPR000182 GNAT domain AFE_2004 86b0e02da575446b345c1c6e1dfff7fb 142 Gene3D G3DSA:3.40.630.30 1 138 4.3E-26 T 12-10-2018 AFE_2004 86b0e02da575446b345c1c6e1dfff7fb 142 SUPERFAMILY SSF55729 1 133 1.28E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFE_2694 d1abb9bf502103511bfc91b7e9a885d1 212 Pfam PF11180 Protein of unknown function (DUF2968) 6 176 2.3E-32 T 12-10-2018 IPR021350 Protein of unknown function DUF2968 AFE_1215 ed89463c972a604f380f8b781d1c4b57 408 Pfam PF01385 Probable transposase 176 289 8.1E-16 T 12-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFE_1215 ed89463c972a604f380f8b781d1c4b57 408 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 260 345 1.8E-10 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFE_1215 ed89463c972a604f380f8b781d1c4b57 408 Pfam PF07282 Putative transposase DNA-binding domain 318 386 3.1E-21 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFE_1215 ed89463c972a604f380f8b781d1c4b57 408 Pfam PF12323 Helix-turn-helix domain 1 42 9.0E-16 T 12-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain AFE_0769 27b2119114be15e148565f6b577e7c5d 132 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 131 3.0E-27 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 AFE_0769 27b2119114be15e148565f6b577e7c5d 132 Gene3D G3DSA:3.30.420.270 60 127 1.3E-8 T 12-10-2018 AFE_1031 793d5bc88ba20740091bd8c3c382433b 92 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 41 3.3E-5 T 12-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AFE_2575 c83671f28d2a7ae8623ddb938135b28f 389 SUPERFAMILY SSF52172 38 111 7.68E-7 T 12-10-2018 IPR011006 CheY-like superfamily AFE_0764 c05a5fd47426109c1286a87f414aef1c 264 Pfam PF01925 Sulfite exporter TauE/SafE 8 258 8.4E-52 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFE_1722 d5cfea832ce3c782462cd39baad50bc9 122 Pfam PF16694 Cytochrome P460 12 83 2.4E-6 T 12-10-2018 IPR032033 Cytochrome P460 AFE_1367 c7e5ec29c5528e281f70c920a33bd26e 75 SUPERFAMILY SSF46689 2 66 9.14E-22 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFE_1367 c7e5ec29c5528e281f70c920a33bd26e 75 Gene3D G3DSA:1.10.10.10 5 72 1.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFE_1367 c7e5ec29c5528e281f70c920a33bd26e 75 Pfam PF04255 Protein of unknown function (DUF433) 6 61 9.2E-27 T 12-10-2018 IPR007367 Protein of unknown function DUF433 AFE_2345 61a810f5fc717d24c83542c43b9dfe1c 185 SMART SM00464 6 181 1.8E-5 T 12-10-2018 IPR003111 Lon, substrate-binding domain AFE_2345 61a810f5fc717d24c83542c43b9dfe1c 185 Gene3D G3DSA:2.30.130.40 5 109 7.3E-24 T 12-10-2018 AFE_2345 61a810f5fc717d24c83542c43b9dfe1c 185 SUPERFAMILY SSF88697 8 180 5.22E-32 T 12-10-2018 IPR015947 PUA-like superfamily AFE_2345 61a810f5fc717d24c83542c43b9dfe1c 185 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 8 108 3.4E-12 T 12-10-2018 IPR003111 Lon, substrate-binding domain AFE_2962 fbb0ca768223d56ba092297ebac85ed3 281 PRINTS PR00164 ABC-2 type transport system membrane protein signature 163 187 9.7E-25 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_2962 fbb0ca768223d56ba092297ebac85ed3 281 PRINTS PR00164 ABC-2 type transport system membrane protein signature 220 239 9.7E-25 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_2962 fbb0ca768223d56ba092297ebac85ed3 281 PRINTS PR00164 ABC-2 type transport system membrane protein signature 55 76 9.7E-25 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_2962 fbb0ca768223d56ba092297ebac85ed3 281 PRINTS PR00164 ABC-2 type transport system membrane protein signature 86 108 9.7E-25 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_2962 fbb0ca768223d56ba092297ebac85ed3 281 PRINTS PR00164 ABC-2 type transport system membrane protein signature 200 219 9.7E-25 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_2962 fbb0ca768223d56ba092297ebac85ed3 281 PRINTS PR00164 ABC-2 type transport system membrane protein signature 129 154 9.7E-25 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFE_2962 fbb0ca768223d56ba092297ebac85ed3 281 Pfam PF01061 ABC-2 type transporter 35 242 5.4E-14 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFE_0446 2ad0b8baa586fe52f83cbeea263c3221 231 Pfam PF04367 Protein of unknown function (DUF502) 68 171 4.1E-22 T 12-10-2018 IPR007462 Protein of unknown function DUF502 AFE_0615 dc2ef2f2f3a1891992dcf615f9ea90f4 420 Gene3D G3DSA:3.40.50.2000 120 412 4.2E-59 T 12-10-2018 AFE_0615 dc2ef2f2f3a1891992dcf615f9ea90f4 420 Gene3D G3DSA:3.40.50.2000 212 401 4.2E-59 T 12-10-2018 AFE_0615 dc2ef2f2f3a1891992dcf615f9ea90f4 420 Pfam PF00534 Glycosyl transferases group 1 225 394 1.7E-35 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 AFE_0615 dc2ef2f2f3a1891992dcf615f9ea90f4 420 SUPERFAMILY SSF53756 20 414 4.49E-68 T 12-10-2018 AFE_2603 46eea4d40b99a3531c21da30a73c694c 203 Pfam PF13649 Methyltransferase domain 43 139 7.5E-12 T 12-10-2018 AFE_2603 46eea4d40b99a3531c21da30a73c694c 203 Gene3D G3DSA:3.40.50.150 2 168 4.2E-26 T 12-10-2018 AFE_2603 46eea4d40b99a3531c21da30a73c694c 203 SUPERFAMILY SSF53335 5 183 1.18E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFE_0444 1b1c9e425ca9b473f269bdb6c4f434b7 110 Gene3D G3DSA:3.30.70.2340 1 96 2.9E-28 T 12-10-2018 AFE_0444 1b1c9e425ca9b473f269bdb6c4f434b7 110 Pfam PF12112 Protein of unknown function (DUF3579) 2 85 2.0E-22 T 12-10-2018 IPR021969 Protein of unknown function DUF3579 AFE_2419 1498c6ab52a6b1824072e68d75a2422b 491 Pfam PF01076 Plasmid recombination enzyme 7 184 1.3E-12 T 12-10-2018 IPR001668 Plasmid recombination enzyme GO:0003677|GO:0005727|GO:0006310 AFE_2419 1498c6ab52a6b1824072e68d75a2422b 491 Gene3D G3DSA:3.30.930.30 5 186 1.0E-14 T 12-10-2018 AFE_1762 1db12ea8fd9b00e439c43061316a279d 86 Gene3D G3DSA:3.30.70.860 40 86 9.2E-7 T 12-10-2018 IPR035571 UPF0234-like, C-terminal AFE_1762 1db12ea8fd9b00e439c43061316a279d 86 SUPERFAMILY SSF89963 50 81 1.36E-5 T 12-10-2018 IPR036183 YajQ-like superfamily AFE_0500 20cc86481bfdd571e1acaeac9bc44b5d 137 Gene3D G3DSA:2.170.150.70 5 117 1.9E-14 T 12-10-2018 AFE_0500 20cc86481bfdd571e1acaeac9bc44b5d 137 SUPERFAMILY SSF51316 2 133 4.5E-41 T 12-10-2018 IPR011057 Mss4-like superfamily AFE_0500 20cc86481bfdd571e1acaeac9bc44b5d 137 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 27 114 3.8E-26 T 12-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 AFE_0816 c15ce09227207f27c2cf92968460ce6c 46 Gene3D G3DSA:1.20.1110.10 5 46 3.5E-7 T 12-10-2018 AFE_2844 32b56e070b83ec3e5fbe1e437bba80be 62 Pfam PF01679 Proteolipid membrane potential modulator 1 47 3.3E-6 T 12-10-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 AFE_2171 f70325a0ac160b661cc19a7c9002ae42 455 Pfam PF13200 Putative glycosyl hydrolase domain 102 411 8.4E-119 T 12-10-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 AFE_2171 f70325a0ac160b661cc19a7c9002ae42 455 SUPERFAMILY SSF51445 162 410 4.5E-9 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily AFE_2891 29bb544498cf45ff576e48dfb7f7438d 116 Pfam PF09685 Domain of unknown function (DUF4870) 14 115 1.1E-27 T 12-10-2018 IPR019109 Protein of unknown function DUF4870 AFE_1106 7dacefbec3a451a2269077c7a4248ea8 549 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 361 435 1.9E-10 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFE_2285 9aefa39610b40ef32dcebaedab16a4b5 225 Pfam PF06299 Protein of unknown function (DUF1045) 56 209 1.7E-42 T 12-10-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFE_2285 9aefa39610b40ef32dcebaedab16a4b5 225 TIGRFAM TIGR03223 Phn_opern_protn: putative phosphonate metabolism protein 2 218 3.3E-80 T 12-10-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFE_3259 aedcd7aeabf6cdaf7a22edc0513ed5a1 486 Pfam PF02646 RmuC family 162 451 1.9E-94 T 12-10-2018 IPR003798 DNA recombination RmuC AFE_1412 b8f575e2300a32152c215df1439dd367 168 Pfam PF11663 Toxin with endonuclease activity, of toxin-antitoxin system 16 152 2.5E-62 T 12-10-2018 IPR021679 Toxin endonuclease, YhaV GO:0004540|GO:0110001 AFE_1066 069ae43702c2553aba65cbc95ad43026 337 Pfam PF13728 F plasmid transfer operon protein 47 276 4.4E-63 T 12-10-2018 IPR039555 F plasmid transfer operon protein AFE_1565 35d9a0cc28796bb1ded689fae4830e92 353 Pfam PF07120 Protein of unknown function (DUF1376) 51 138 2.9E-8 T 12-10-2018 IPR010781 Protein of unknown function DUF1376 AFE_1384 a6edfbf30d1f29ac0ab8e4e56eb60d8a 113 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 9 102 1.5E-21 T 12-10-2018 IPR009241 Toxin HigB-like AFE_2097 07d16b2da8446d569fd31a6846875150 434 Gene3D G3DSA:1.10.490.140 142 258 2.7E-9 T 12-10-2018 AFE_2097 07d16b2da8446d569fd31a6846875150 434 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 78 399 1.1E-27 T 12-10-2018 IPR003776 YcaO-like domain AFE_2723 eb503d5ac4b1afe4e064532047f89695 336 ProSitePatterns PS01276 Peptidase family U32 signature. 166 184 - T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFE_2723 eb503d5ac4b1afe4e064532047f89695 336 Pfam PF01136 Peptidase family U32 82 335 5.5E-64 T 12-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFE_3115 9b5162af3103a5983f0fb18a8c9a0e6f 161 Pfam PF06146 Phosphate-starvation-inducible E 79 146 6.8E-14 T 12-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like AFE_0920 03d74a6dfc8287a7054a01f272359250 456 Pfam PF01566 Natural resistance-associated macrophage protein 71 426 5.6E-56 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFE_0721 a8b0e14824884b2c628335ea715a37f4 132 SUPERFAMILY SSF46458 19 126 5.37E-21 T 12-10-2018 IPR009050 Globin-like superfamily AFE_0721 a8b0e14824884b2c628335ea715a37f4 132 Gene3D G3DSA:1.10.490.10 16 130 8.0E-26 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFE_0721 a8b0e14824884b2c628335ea715a37f4 132 Pfam PF01152 Bacterial-like globin 21 112 3.7E-8 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 AFE_2485 fe32f631343e50c66b62ee2b4a3065ec 59 Pfam PF11809 Domain of unknown function (DUF3330) 19 59 3.0E-16 T 12-10-2018 IPR021767 Transposon Tn21 modulator protein AFE_3237 75dda6f41417b9cd36b1064c4aad44b9 222 SUPERFAMILY SSF53474 3 203 2.2E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_3237 75dda6f41417b9cd36b1064c4aad44b9 222 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 21 138 1.1E-5 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 AFE_3237 75dda6f41417b9cd36b1064c4aad44b9 222 Gene3D G3DSA:3.40.50.1820 3 216 1.2E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold AFE_1998 39219b7dede565d932cc45a1bc268edb 143 Pfam PF16245 Domain of unknown function (DUF4902) 20 137 9.7E-51 T 12-10-2018 IPR032598 Protein of unknown function DUF4902 AFE_1998 39219b7dede565d932cc45a1bc268edb 143 Gene3D G3DSA:3.10.450.610 7 142 5.2E-44 T 12-10-2018 AFE_1661 e35b273debbc09dabd5574b9da7bb381 825 Hamap MF_01871 UPF0753 protein . 12 816 24.23 T 12-10-2018 IPR018752 Uncharacterised protein family UPF0753 AFE_1661 e35b273debbc09dabd5574b9da7bb381 825 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 17 801 1.2E-268 T 12-10-2018 IPR018752 Uncharacterised protein family UPF0753 AFE_0171 d5b4d339030568e43c208eff394b1c01 534 Gene3D G3DSA:1.20.1250.20 213 439 4.9E-10 T 12-10-2018 AFE_0171 d5b4d339030568e43c208eff394b1c01 534 SUPERFAMILY SSF103473 19 495 5.67E-37 T 12-10-2018 IPR036259 MFS transporter superfamily AFE_0171 d5b4d339030568e43c208eff394b1c01 534 Gene3D G3DSA:1.20.1250.20 22 209 1.5E-21 T 12-10-2018 AFE_0171 d5b4d339030568e43c208eff394b1c01 534 Pfam PF07690 Major Facilitator Superfamily 33 423 4.0E-27 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFE_0828 95a1954890ee3daf645b76843643b5a0 355 Pfam PF13310 Virulence protein RhuM family 76 327 1.1E-111 T 12-10-2018 IPR011204 Virulence protein RhuM-like AFE_0828 95a1954890ee3daf645b76843643b5a0 355 PIRSF PIRSF015268 10 352 2.2E-140 T 12-10-2018 IPR011204 Virulence protein RhuM-like AFE_0588 112d1907a1111e7d9d8e2fcba7847700 207 SUPERFAMILY SSF56281 23 147 2.43E-7 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFE_2135 1e55f2dcf53667dc30e20569a261fac8 312 Pfam PF02470 MlaD protein 45 112 1.5E-13 T 12-10-2018 IPR003399 Mce/MlaD AFE_2491 4eff482d090df09ab5fc1c9ae007e894 230 Pfam PF09601 Protein of unknown function (DUF2459) 52 208 2.2E-28 T 12-10-2018 IPR011727 Conserved hypothetical protein CHP02117 AFE_3151 5f19cdbe493d3c975fe2d8212bef9823 183 SUPERFAMILY SSF49503 53 177 5.79E-15 T 12-10-2018 IPR008972 Cupredoxin AFE_3151 5f19cdbe493d3c975fe2d8212bef9823 183 Gene3D G3DSA:2.60.40.420 39 179 1.6E-17 T 12-10-2018 IPR008972 Cupredoxin AFE_0485 1cb0ed951806489b772ab3f28f4a0908 206 Pfam PF01618 MotA/TolQ/ExbB proton channel family 70 190 1.1E-36 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel AFE_0783 5df8c09522efabbee902695f7e5d0376 146 Pfam PF11533 Protein of unknown function (DUF3225) 23 143 8.9E-55 T 12-10-2018 IPR024507 Protein of unknown function DUF3225 AFE_0783 5df8c09522efabbee902695f7e5d0376 146 Gene3D G3DSA:3.10.450.50 19 143 2.0E-47 T 12-10-2018 AFE_0783 5df8c09522efabbee902695f7e5d0376 146 SUPERFAMILY SSF54427 19 143 2.42E-34 T 12-10-2018 IPR032710 NTF2-like domain superfamily AFE_1485 cfd1e31904d9a64fba297d44e2cf3c13 217 Pfam PF01618 MotA/TolQ/ExbB proton channel family 72 185 1.9E-25 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel AFE_1903 c04f2411e3276cb415c910e5bdd3ff78 153 Pfam PF02620 Uncharacterized ACR, COG1399 59 145 2.7E-9 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD AFE_0919 b433bfeaf1f45355cce86e305f68bc51 213 Pfam PF14235 Domain of unknown function (DUF4337) 51 209 2.1E-38 T 12-10-2018 IPR025570 Protein of unknown function DUF4337 AFE_2033 7947795b79dc9ef5f798ea8e285a3c34 103 Gene3D G3DSA:3.10.450.40 28 98 3.8E-10 T 12-10-2018 AFE_2033 7947795b79dc9ef5f798ea8e285a3c34 103 Pfam PF03413 Peptidase propeptide and YPEB domain 36 94 2.4E-9 T 12-10-2018 IPR025711 PepSY domain AFE_2775 21b5486abdbe3ae82176d1c342727188 261 Pfam PF01925 Sulfite exporter TauE/SafE 13 252 1.1E-52 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFE_2713 59b81cff2bda0fa14c78aa65af065355 124 Pfam PF14373 Superinfection immunity protein 34 77 4.2E-16 T 12-10-2018 IPR016410 Bacteriophage-associated immunity protein AFE_1524 e69fbe27e3a1e5485e7f678d1e5b0392 275 Pfam PF07357 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) 23 271 2.4E-101 T 12-10-2018 IPR009953 Dinitrogenase reductase ADP-ribosyltransferase GO:0009399|GO:0030701 AFE_0261 6df6d31d58fb55bba81ee981d6ea25c4 92 Pfam PF02325 YGGT family 14 83 3.1E-22 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 AFE_0139 9dc0f7b5bc82b70691442dec18a0e137 254 Pfam PF02582 Uncharacterised ACR, YagE family COG1723 44 210 9.6E-21 T 12-10-2018 IPR003734 Domain of unknown function DUF155 AFE_2390 8c9a3904220ffd6651c34599c854582e 87 Pfam PF04380 Membrane fusogenic activity 2 74 1.3E-23 T 12-10-2018 IPR007475 Membrane fusogenic activity AFE_1075 acd2a4c8a01b26d606e90841ee4564bd 372 Gene3D G3DSA:3.40.30.10 225 370 3.5E-14 T 12-10-2018 AFE_0988 4c328cbdd10bb3afb8d09a88a0f90fc3 346 Pfam PF01594 AI-2E family transporter 17 335 2.0E-21 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like AFE_1992 7c1b017c2c95c7c4a598ae10d83fcb0c 400 Gene3D G3DSA:1.50.10.150 15 363 5.2E-20 T 12-10-2018 IPR038665 Voltage-dependent anion channel superfamily AFE_1992 7c1b017c2c95c7c4a598ae10d83fcb0c 400 Pfam PF03595 Voltage-dependent anion channel 18 349 8.1E-80 T 12-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 AFE_2239 13fe76e4ee657a845ea4bdc0cb95df39 347 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 4 347 4.0E-64 T 12-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 AFE_2919 a3e3ee9afde6b89b38a3ba41f380006b 123 Pfam PF13488 Glycine zipper 36 75 5.5E-9 T 12-10-2018 IPR039567 Glycine zipper domain AFE_1326 3b38c1cd0d51c134a6609113665045cc 230 Pfam PF08346 AntA/AntB antirepressor 21 109 1.6E-29 T 12-10-2018 IPR013557 AntA/AntB antirepressor AFE_1068 2a3e451a0b15ea15d6433fb9abae036e 1218 Pfam PF07916 TraG-like protein, N-terminal region 3 509 7.2E-32 T 12-10-2018 IPR012931 TraG-like, N-terminal AFE_0074 e8289390d3e2e51b3ea3e163f0380c3e 336 Pfam PF02706 Chain length determinant protein 86 162 2.5E-12 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 AFE_1696 a0db3a333b29c1c8d6e74cdfe93fbea6 333 Pfam PF03524 Conjugal transfer protein 107 317 1.8E-10 T 12-10-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX AFE_2357 610f5c85f63f6b3b4ef944420a9d9416 377 Pfam PF06804 NlpB/DapX lipoprotein 98 276 2.3E-5 T 12-10-2018 IPR010653 NlpB/DapX lipoprotein AFE_2054 fb820fca42f210667ac27edcff9105d1 260 Pfam PF04338 Protein of unknown function, DUF481 52 260 2.9E-23 T 12-10-2018 IPR007433 Protein of unknown function DUF481 AFE_1693 68dc1bc3d226c84433697235eea61d5b 285 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 42 239 1.9E-11 T 12-10-2018 IPR018713 Domain of unknown function DUF2236 AFE_1839 ddf7fdf25898a49b34c702880dfa03b3 138 SUPERFAMILY SSF54593 8 132 8.06E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFE_1839 ddf7fdf25898a49b34c702880dfa03b3 138 Gene3D G3DSA:3.10.180.10 8 132 2.9E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFE_2393 26f3e807f5bbf0b07f7ec26532a2934d 151 Pfam PF01527 Transposase 7 40 1.6E-5 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 AFE_2393 26f3e807f5bbf0b07f7ec26532a2934d 151 Pfam PF01527 Transposase 46 120 3.5E-6 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 AFE_3112 3a3756a6c3c18e87103330fe65abf50e 614 Pfam PF05140 ResB-like family 24 592 7.0E-121 T 12-10-2018 IPR007816 ResB-like domain AFE_1122 382140d03047bada7613a658825859c1 85 Pfam PF13223 Protein of unknown function (DUF4031) 3 80 4.9E-32 T 12-10-2018 IPR025109 Domain of unknown function DUF4031 AFE_2968 778717a8682a9790b06daf65ec92482b 523 Pfam PF03567 Sulfotransferase family 43 198 4.2E-8 T 12-10-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 AFE_2968 778717a8682a9790b06daf65ec92482b 523 Gene3D G3DSA:3.40.50.300 21 209 5.8E-7 T 12-10-2018 AFE_1831 d9cc218388e3eeed4badb4fbc8e0eb2c 180 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 103 177 3.4E-15 T 12-10-2018 IPR018550 Lipid A 3-O-deacylase-related AFE_1831 d9cc218388e3eeed4badb4fbc8e0eb2c 180 Gene3D G3DSA:2.40.160.20 94 179 2.9E-11 T 12-10-2018 AFE_1029 1831e3120ce522ec7cc57b42c1587ba2 227 Pfam PF04402 Protein of unknown function (DUF541) 45 195 7.9E-6 T 12-10-2018 IPR007497 Protein of unknown function DUF541 AFE_0362 a17585cf4e9ade5f498a3a6a8bb354d2 118 Pfam PF12732 YtxH-like protein 6 71 6.7E-15 T 12-10-2018 IPR024623 Uncharacterised protein family YtxH AFE_1991 86e3b52659d37ee160f52888795ab335 428 Gene3D G3DSA:2.40.160.10 17 322 1.1E-16 T 12-10-2018 IPR023614 Porin domain superfamily AFE_2925 6b261fcb4f65763cabe72d40f6aec63e 563 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 69 230 8.8E-17 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFE_0408 de44e18870b0498ba66ffbf86bbad946 106 Pfam PF11127 Protein of unknown function (DUF2892) 38 98 1.9E-14 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 AFE_1982 d6a0f0d22677af85017a0b2a3f01f7b5 148 Pfam PF13767 Domain of unknown function (DUF4168) 65 139 3.8E-12 T 12-10-2018 IPR025433 Domain of unknown function DUF4168 AFE_1243 ff66d9bb441e580687bdbf6eccbf8b1e 104 Gene3D G3DSA:1.20.120.910 7 79 1.1E-9 T 12-10-2018 AFE_0486 68336a7d6a2ce6405997b4d78b2fc29d 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 130 3.4E-33 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 AFE_0486 68336a7d6a2ce6405997b4d78b2fc29d 134 Gene3D G3DSA:3.30.420.270 59 128 5.8E-13 T 12-10-2018 AFE_1604 c06c6f2267e858ef2956f77db636603e 377 Pfam PF12698 ABC-2 family transporter protein 25 370 6.4E-44 T 12-10-2018 AFE_1040 01da9be8c8ac2639a780e0be8b3ab646 230 TIGRFAM TIGR03116 cas5_csf3: CRISPR type IV/AFERR-associated protein Csf3 3 217 1.2E-104 T 12-10-2018 IPR017547 CRISPR type IV/AFERR-associated protein Csf3 AFE_2207 8ed495daa2679b2d85db6574195a5161 414 SUPERFAMILY SSF54593 70 392 5.16E-8 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFE_2965 38bb616fdf5abd32893cae7e152daf1f 213 Pfam PF13946 Domain of unknown function (DUF4214) 24 72 2.2E-6 T 12-10-2018 IPR025282 Domain of unknown function DUF4214 AFE_0105 8ab02d180a0c20e5be532054827b31d5 421 Pfam PF01566 Natural resistance-associated macrophage protein 43 381 4.9E-68 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 AFE_1957 3b496a6ff8272254a5265f73aa844a20 1184 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 845 1184 9.0E-65 T 12-10-2018 IPR007452 Translocation and assembly module TamB AFE_2299 3d53f0785102cd06bc932448d684980f 225 Pfam PF01618 MotA/TolQ/ExbB proton channel family 77 191 2.3E-28 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel AFE_2258 bf176ad1a6259b391cca10b1da45d0fc 296 Pfam PF01925 Sulfite exporter TauE/SafE 9 278 1.1E-46 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021