locus-tag	class	description
F6A13_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
F6A13_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
F6A13_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
F6A13_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F6A13_00050	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
F6A13_00055	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
F6A13_00060	ENOG4107QMS	site-determining protein
F6A13_00065	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
F6A13_00070	ENOG4108Z4U	Ferredoxin
F6A13_00080	ENOG4108RPN	Protein smg homolog
F6A13_00085	ENOG4105C79	DNA protecting protein DprA
F6A13_00095	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
F6A13_00100	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
F6A13_00105	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
F6A13_00115	ENOG4105ES5	Histidine kinase
F6A13_00120	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F6A13_00135	ENOG41090Y2	cytochrome C
F6A13_00145	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
F6A13_00175	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
F6A13_00180	ENOG4107RDB	Major Facilitator
F6A13_00200	ENOG4108UYB	regulatoR
F6A13_00205	ENOG4105BZU	Histidine kinase
F6A13_00235	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
F6A13_00255	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
F6A13_00260	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
F6A13_00275	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
F6A13_00280	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
F6A13_00325	ENOG4105CRE	cytochrome C
F6A13_00330	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
F6A13_00340	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F6A13_00345	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F6A13_00350	ENOG4105UBK	short-chain dehydrogenase reductase
F6A13_00355	ENOG41090Y2	cytochrome C
F6A13_00365	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F6A13_00380	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
F6A13_00385	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
F6A13_00390	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
F6A13_00395	ENOG41087PG	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
F6A13_00400	ENOG4105VG0	50S ribosomal protein l34
F6A13_00405	ENOG4105C5H	ABC transporter
F6A13_00415	ENOG4105CW7	secretion protein, HlyD family
F6A13_00470	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
F6A13_00495	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
F6A13_00505	ENOG4105C9M	aspartyl-trna synthetase
F6A13_00510	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
F6A13_00520	ENOG4105CDY	transcriptional regulatory protein
F6A13_00525	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
F6A13_00530	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
F6A13_00535	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
F6A13_00540	ENOG4107YD3	Thioesterase
F6A13_00545	ENOG4105E02	MotA TolQ exbB proton channel
F6A13_00550	ENOG4105M8F	Biopolymer transport protein exbD tolR
F6A13_00560	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
F6A13_00565	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
F6A13_00570	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
F6A13_00580	ENOG4105KCK	Peptidoglycan-associated lipoprotein
F6A13_00615	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
F6A13_00620	ENOG4105D3Q	Sugar transferase
F6A13_00650	ENOG4108MX3	Polysaccharide Biosynthesis Protein
F6A13_00655	ENOG4107QVI	Methyltransferase, type 11
F6A13_00665	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
F6A13_00675	ENOG4108TJN	glycosyl transferase group 1
F6A13_00685	ENOG4108KBE	Glycosyl transferase, family 2
F6A13_00790	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
F6A13_00805	ENOG4105E0F	Histidine kinase
F6A13_00810	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
F6A13_00820	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
F6A13_00855	ENOG4105ED9	Protein of unknown function (DUF455)
F6A13_00860	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F6A13_00870	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
F6A13_00875	ENOG4107ZVW	dihydroneopterin aldolase
F6A13_00880	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
F6A13_00890	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
F6A13_00905	ENOG4105D4P	Coproporphyrinogen iii oxidase
F6A13_00910	ENOG4105DZ2	Transcriptional regulator
F6A13_00920	ENOG4105XA0	heptosyltransferase ii
F6A13_00930	ENOG4105CQB	FAD linked oxidase domain protein
F6A13_00935	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
F6A13_00940	ENOG41082RQ	UPF0102 protein
F6A13_00945	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
F6A13_00950	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
F6A13_00960	ENOG4108KU3	Integrase
F6A13_00975	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
F6A13_01015	ENOG4105CVR	type I restriction-modification system
F6A13_01040	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F6A13_01055	ENOG4105IH7	synthase
F6A13_01075	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
F6A13_01085	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
F6A13_01090	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
F6A13_01095	ENOG4105DHJ	ABC, transporter
F6A13_01100	ENOG4105CY3	ABC transporter, permease
F6A13_01105	ENOG4107PE3	Mammalian cell entry related domain protein
F6A13_01120	ENOG4105DA5	(ABC) transporter
F6A13_01125	ENOG41082I2	s4 domain protein
F6A13_01130	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
F6A13_01140	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
F6A13_01155	ENOG4105C75	arginyL-tRNA synthetase
F6A13_01160	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F6A13_01165	ENOG4105DND	Transcriptional regulator
F6A13_01170	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
F6A13_01175	ENOG4105CGK	Exodeoxyribonuclease III
F6A13_01185	ENOG4105D6S	protein involved in catabolism of external DNA
F6A13_01190	ENOG4108U78	Glutathione S-transferase
F6A13_01195	ENOG4105CGK	Exodeoxyribonuclease III
F6A13_01200	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
F6A13_01205	ENOG4108YZY	peptidylprolyl cis-trans isomerase
F6A13_01210	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
F6A13_01215	ENOG4105E2X	shikimate dehydrogenase
F6A13_01220	ENOG4107QHF	type ii secretion system protein e
F6A13_01225	ENOG4107TUY	Histidine kinase
F6A13_01230	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F6A13_01240	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
F6A13_01245	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
F6A13_01250	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F6A13_01260	ENOG4105E4C	Lytic transglycosylase catalytic
F6A13_01265	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
F6A13_01275	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
F6A13_01280	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
F6A13_01285	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
F6A13_01290	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
F6A13_01305	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
F6A13_01310	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
F6A13_01315	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
F6A13_01320	ENOG4105CPF	Cell wall formation (By similarity)
F6A13_01325	ENOG4105D4A	Cell wall formation (By similarity)
F6A13_01330	ENOG4105DFU	Cell wall formation (By similarity)
F6A13_01335	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
F6A13_01340	ENOG4105CNI	cell division protein FtsW
F6A13_01345	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
F6A13_01350	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
F6A13_01355	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
F6A13_01360	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
F6A13_01365	ENOG4105CJN	penicillin-binding protein
F6A13_01375	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
F6A13_01380	ENOG4108V6E	Cell division protein mraZ
F6A13_01395	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
F6A13_01400	ENOG4108IQE	Amp-dependent synthetase and ligase
F6A13_01405	ENOG4107MKT	Stringent starvation protein a
F6A13_01410	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F6A13_01420	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
F6A13_01425	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
F6A13_01430	ENOG4105M6F	mutator MutT protein
F6A13_01435	ENOG4105CKK	Glycosyl transferase, family 2
F6A13_01440	ENOG4107T94	Endo-14-beta-xylanase
F6A13_01445	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
F6A13_01465	ENOG4106WTF	Glycosyl transferase, family 2
F6A13_01470	ENOG4105D16	lipopolysaccharide heptosyltransferase i
F6A13_01480	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
F6A13_01485	ENOG4105D1S	lipid A biosynthesis
F6A13_01490	ENOG4105C87	Aminotransferase class I and II
F6A13_01495	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
F6A13_01500	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
F6A13_01505	ENOG4105MJ2	Competence protein
F6A13_01510	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F6A13_01515	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
F6A13_01525	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
F6A13_01535	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
F6A13_01540	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
F6A13_01545	ENOG4105C4B	ABC transporter, permease
F6A13_01550	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
F6A13_01555	ENOG4108EX3	reductase
F6A13_01575	ENOG4105R8C	Transcriptional regulator
F6A13_01580	ENOG4105CAS	nag kinase
F6A13_01585	ENOG4105CW7	secretion protein, HlyD family
F6A13_01595	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
F6A13_01600	ENOG4105VZ9	UPF0235 protein
F6A13_01605	ENOG4108VIA	integral membrane protein
F6A13_01610	ENOG4105II7	pyrroline-5-carboxylate reductase
F6A13_01615	ENOG4105DFA	alanine racemase domain protein
F6A13_01620	ENOG4105CZX	twitching motility protein
F6A13_01625	ENOG4105CZX	twitching motility protein
F6A13_01650	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
F6A13_01655	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
F6A13_01660	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
F6A13_01665	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
F6A13_01685	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
F6A13_01690	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
F6A13_01695	ENOG4108Z1B	Cyclase dehydrase
F6A13_01700	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F6A13_01705	ENOG41090R7	Ferric uptake
F6A13_01710	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
F6A13_01715	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F6A13_01720	ENOG4105K46	50S ribosomal protein l27
F6A13_01725	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
F6A13_01730	ENOG4108UPT	UPF0178 protein
F6A13_01760	ENOG4105C26	Dehydrogenase
F6A13_01765	ENOG4105CHH	sulfate transporter
F6A13_01775	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
F6A13_01780	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F6A13_01790	ENOG4105DWV	Homoserine O-trans-acetylase
F6A13_01795	ENOG4105DWV	Homoserine O-trans-acetylase
F6A13_01805	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F6A13_01810	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
F6A13_01815	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
F6A13_01825	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
F6A13_01830	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
F6A13_01835	ENOG4107YIM	Involved in the transcription termination process (By similarity)
F6A13_01855	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F6A13_01880	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F6A13_01895	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
F6A13_01900	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
F6A13_01905	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
F6A13_01910	ENOG4108VZM	50s ribosomal protein L10
F6A13_01915	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
F6A13_01920	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F6A13_01925	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F6A13_01930	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
F6A13_01935	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
F6A13_01940	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F6A13_01945	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F6A13_01950	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
F6A13_01955	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
F6A13_01960	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
F6A13_01965	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
F6A13_01970	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F6A13_01975	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
F6A13_01980	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
F6A13_01985	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
F6A13_01990	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
F6A13_02000	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
F6A13_02005	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
F6A13_02010	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
F6A13_02015	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F6A13_02020	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
F6A13_02025	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
F6A13_02030	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
F6A13_02035	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
F6A13_02040	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
F6A13_02045	ENOG41084RK	50S ribosomal protein L30
F6A13_02050	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
F6A13_02055	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
F6A13_02060	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
F6A13_02065	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
F6A13_02070	ENOG41067V7	50S ribosomal protein L36
F6A13_02075	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F6A13_02080	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
F6A13_02085	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
F6A13_02090	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F6A13_02095	ENOG4108ZT0	50S ribosomal protein l17
F6A13_02100	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
F6A13_02110	ENOG4105W5Q	DNA repair protein (RadC
F6A13_02120	ENOG410841Q	phosphoesterase PA-phosphatase related protein
F6A13_02140	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
F6A13_02145	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
F6A13_02155	ENOG4105EHV	domain protein
F6A13_02160	ENOG4105EAC	phosphoserine phosphatase
F6A13_02165	ENOG4108JA2	transcriptioN-repair coupling factor
F6A13_02170	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
F6A13_02175	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
F6A13_02180	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
F6A13_02195	ENOG4105C3M	thioredoxin reductase
F6A13_02200	ENOG4105CNU	cell division protein FtsK
F6A13_02205	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
F6A13_02215	ENOG4105D1H	recombination factor protein RarA
F6A13_02220	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
F6A13_02230	ENOG4108PXI	ErfK YbiS YcfS YnhG
F6A13_02265	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
F6A13_02270	ENOG4105CHV	Transcription elongation factor NusA
F6A13_02275	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
F6A13_02280	ENOG41082KD	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
F6A13_02285	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
F6A13_02290	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
F6A13_02295	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
F6A13_02305	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
F6A13_02315	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F6A13_02320	ENOG4107RZZ	dna polymerase iii epsilon subunit
F6A13_02340	ENOG4105CDH	Citrulline--aspartate ligase
F6A13_02345	ENOG4105DBV	ornithine carbamoyltransferase
F6A13_02350	ENOG4105C8Y	Acetylornithine aminotransferase
F6A13_02355	ENOG4105CFH	Aspartokinase
F6A13_02385	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
F6A13_02390	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
F6A13_02395	ENOG4105E9H	Lytic Murein transglycosylase
F6A13_02400	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
F6A13_02425	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F6A13_02430	ENOG4108HMX	isocitrate dehydrogenase (NADP)
F6A13_02435	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
F6A13_02445	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
F6A13_02455	ENOG4108YZA	Nitrogen regulatory protein pii
F6A13_02460	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6A13_02465	ENOG4105C34	Pseudouridine synthase
F6A13_02470	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
F6A13_02475	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
F6A13_02480	ENOG4107RAT	Ribulose bisphosphate carboxylase large chain, catalytic domain
F6A13_02485	ENOG41080FP	Hydrolase
F6A13_02490	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
F6A13_02500	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
F6A13_02505	ENOG4107QTZ	amino acid
F6A13_02510	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
F6A13_02530	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
F6A13_02540	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F6A13_02550	ENOG4107WP9	Histidine kinase
F6A13_02555	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
F6A13_02560	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
F6A13_02565	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
F6A13_02570	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
F6A13_02575	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
F6A13_02585	ENOG4105DJF	DNA polymerase III, delta' subunit
F6A13_02595	ENOG4105C8T	Leucyl-tRNA synthetase
F6A13_02600	ENOG4105CS1	NAD(P)H quinone oxidoreductase
F6A13_02605	ENOG4108YYC	ycei family
F6A13_02615	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
F6A13_02630	ENOG4105C5F	glutamine synthetase
F6A13_02640	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
F6A13_02645	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
F6A13_02650	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F6A13_02660	ENOG4105CHM	Aminotransferase
F6A13_02665	ENOG4105D6E	homoserine dehydrogenase
F6A13_02680	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
F6A13_02690	ENOG4105CRK	lysyL-tRNA synthetase
F6A13_02695	ENOG4105D60	lipoprotein releasing system transmembrane protein
F6A13_02700	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
F6A13_02710	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
F6A13_02715	ENOG4105E02	MotA TolQ exbB proton channel
F6A13_02720	ENOG4109015	Biopolymer transport protein exbD tolR
F6A13_02735	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
F6A13_02740	ENOG4105W49	UPF0434 protein
F6A13_02745	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
F6A13_02785	ENOG4108V5Q	transglutaminase-like protein
F6A13_02855	ENOG4105CA0	peroxidase
F6A13_02860	ENOG4108RG0	uracil-dna glycosylase
F6A13_02865	ENOG4105CNG	UPF0061 protein
F6A13_02870	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F6A13_02875	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
F6A13_02880	ENOG4107TF3	peptidylprolyl cis-trans isomerase
F6A13_02885	ENOG4107S0N	DJ-1 family
F6A13_02890	ENOG4105CN1	protease
F6A13_02900	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
F6A13_02915	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
F6A13_02930	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
F6A13_02935	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
F6A13_02940	ENOG4105SYT	Methylenetetrahydrofolate reductase
F6A13_02960	ENOG4107RIQ	Sulfate adenylate transferase
F6A13_02965	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
F6A13_02970	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
F6A13_02975	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
F6A13_02985	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
F6A13_02995	ENOG4105CM2	brancheD-chain amino acid aminotransferase
F6A13_03000	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
F6A13_03030	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
F6A13_03035	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
F6A13_03040	ENOG4105DTN	riboflavin biosynthesis protein ribF
F6A13_03050	ENOG4105CJR	Integral membrane protein (MviN
F6A13_03060	ENOG4105DSJ	YicC domain protein
F6A13_03065	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
F6A13_03070	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
F6A13_03075	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F6A13_03080	ENOG4105KME	endoribonuclease L-psp
F6A13_03090	ENOG4105CB5	ATP-dependent DNA helicase recG
F6A13_03100	ENOG4105C1Q	protoporphyrinogen oxidase
F6A13_03105	ENOG4105C02	permease
F6A13_03110	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
F6A13_03115	ENOG4105NBF	ammecr1 domain protein
F6A13_03125	ENOG4105DFG	type I secretion outer membrane protein
F6A13_03130	ENOG4105CRQ	synthase (Component I)
F6A13_03210	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
F6A13_03215	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
F6A13_03230	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
F6A13_03240	ENOG4105KNY	Microcompartments protein
F6A13_03245	ENOG4105KNY	Microcompartments protein
F6A13_03250	ENOG4105KNY	Microcompartments protein
F6A13_03265	ENOG4107QJE	Chromosome Partitioning Protein
F6A13_03280	ENOG4105FAE	von Willebrand factor, type A
F6A13_03290	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
F6A13_03295	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F6A13_03300	ENOG4105C01	Dihydroxy-acid dehydratase
F6A13_03305	ENOG4105EKE	dihydroorotase
F6A13_03330	ENOG4108TWJ	NADH dehydrogenase subunit 5
F6A13_03335	ENOG4105EVH	UPF0753 protein
F6A13_03350	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
F6A13_03375	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
F6A13_03385	ENOG4108R1E	Serine threonine protein phosphatase 1
F6A13_03460	ENOG4108NF7	phage-type endonuclease
F6A13_03525	ENOG4105CDU	Replicative dna helicase
F6A13_03535	ENOG4105WJ3	XRE family Transcriptional regulator
F6A13_03655	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
F6A13_03685	ENOG4107QMH	DNA methylase
F6A13_03710	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F6A13_03750	ENOG4105C1J	atp-dependent rna helicase
F6A13_03755	ENOG4105VEQ	Cold shock protein
F6A13_03760	ENOG4105C25	Primosomal protein n'
F6A13_03765	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
F6A13_03775	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
F6A13_03785	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
F6A13_03790	ENOG4105C9A	Phoh family
F6A13_03795	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
F6A13_03800	ENOG4108JU5	Magnesium and cobalt efflux protein
F6A13_03805	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
F6A13_03810	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
F6A13_03820	ENOG4105DIK	(ABC) transporter
F6A13_03830	ENOG4105FAV	ABC, transporter
F6A13_03875	ENOG4107T8Q	Glycosyl transferase (Group 1
F6A13_03880	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
F6A13_03885	ENOG4105BZ1	(ABC) transporter
F6A13_03890	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
F6A13_03900	ENOG4105CVJ	phosphoglycerate mutase
F6A13_03915	ENOG4105F2W	methyltransferase
F6A13_03920	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F6A13_03930	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F6A13_03940	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
F6A13_03945	ENOG4105E66	phosphoriboisomerase A
F6A13_03960	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F6A13_03990	ENOG4105E2S	oxidase) subunit II
F6A13_03995	ENOG4105BZ9	Cytochrome C oxidase, subunit I
F6A13_04000	ENOG4105CCU	oxidase (Subunit III)
F6A13_04010	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
F6A13_04015	ENOG4107RDB	Major Facilitator
F6A13_04020	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
F6A13_04025	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
F6A13_04030	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
F6A13_04035	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
F6A13_04045	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
F6A13_04050	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
F6A13_04060	ENOG4105DFU	Cell wall formation (By similarity)
F6A13_04065	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
F6A13_04070	ENOG4105DHJ	ABC, transporter
F6A13_04075	ENOG4105CY3	ABC transporter, permease
F6A13_04095	ENOG4105D06	uba thif-type nad fad binding protein
F6A13_04110	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
F6A13_04120	ENOG4105K63	Thioredoxin
F6A13_04125	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
F6A13_04130	ENOG4105VFB	Binds the 23S rRNA (By similarity)
F6A13_04135	ENOG4105C6K	Malic enzyme
F6A13_04140	ENOG4105IPI	Membrane
F6A13_04145	ENOG4105C01	Dihydroxy-acid dehydratase
F6A13_04155	ENOG4107QZM	n-acetylglutamate synthase
F6A13_04160	ENOG4105M85	Bola protein
F6A13_04165	ENOG4105K9H	YciI-like protein
F6A13_04170	ENOG4107835	probably involved in intracellular septation (By similarity)
F6A13_04180	ENOG4105ECY	inositol monophosphatase
F6A13_04185	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
F6A13_04195	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
F6A13_04200	ENOG4105C3J	Cysteine desulfurase
F6A13_04205	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
F6A13_04210	ENOG4108Z4V	iron-sulfur cluster assembly
F6A13_04220	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
F6A13_04225	ENOG4108ZIT	Ferredoxin, 2FE-2S
F6A13_04230	ENOG4105WVQ	Fe-S assembly protein IscX
F6A13_04235	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
F6A13_04240	ENOG4105D78	K07001 NTE family protein
F6A13_04265	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
F6A13_04290	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
F6A13_04295	ENOG4107QPD	alcohol dehydrogenase
F6A13_04300	ENOG4105C4W	S-formylglutathione hydrolase
F6A13_04305	ENOG4107R11	Transcriptional regulator
F6A13_04320	ENOG4105DPX	Hydrogenase, large subunit
F6A13_04360	ENOG41083MR	nifu domain-containing protein
F6A13_04370	ENOG4105C8H	hydrogenase maturation protein Hypf
F6A13_04375	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
F6A13_04380	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
F6A13_04385	ENOG4105CQS	hydrogenase expression formation protein HypD
F6A13_04390	ENOG4105C45	hydrogenase expression formation protein (HypE)
F6A13_04395	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
F6A13_04420	ENOG4105C7B	Threonine dehydratase
F6A13_04445	ENOG4108Z20	Acyl-transferase
F6A13_04450	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
F6A13_04455	ENOG4105BZ8	glutamate synthase
F6A13_04460	ENOG4105CBC	glutamate synthase
F6A13_04465	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
F6A13_04470	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
F6A13_04475	ENOG4105D49	3-dehydroquinate synthase
F6A13_04480	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
F6A13_04510	ENOG4108Z6B	deaminase
F6A13_04525	ENOG4105C98	muts2 protein
F6A13_04530	ENOG4105C7K	acetolactate synthase
F6A13_04535	ENOG4108ZP8	Acetolactate synthase small subunit
F6A13_04540	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
F6A13_04545	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
F6A13_04550	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
F6A13_04560	ENOG4107YZX	Universal stress protein
F6A13_04565	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
F6A13_04570	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
F6A13_04585	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
F6A13_04590	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
F6A13_04620	ENOG4105HF0	Membrane
F6A13_04625	ENOG4105E02	MotA TolQ exbB proton channel
F6A13_04630	ENOG4105M8F	Biopolymer transport protein exbD tolR
F6A13_04645	ENOG4107QUY	Guanine deaminase
F6A13_04650	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
F6A13_04685	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
F6A13_04705	ENOG41084WP	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
F6A13_04710	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F6A13_04760	ENOG4105C2D	reductase
F6A13_04840	ENOG4107RDB	Major Facilitator
F6A13_04845	ENOG4105CMQ	Chloride channel
F6A13_04880	ENOG4105W2Z	cytochrome C, class I
F6A13_04910	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F6A13_04920	ENOG4105DUM	transcriptional regulator, lysR family
F6A13_04965	ENOG4105C57	major facilitator superfamily
F6A13_04975	ENOG4107TPS	domain protein
F6A13_04990	ENOG41090A4	Pterin carbinolamine dehydratase
F6A13_05000	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
F6A13_05005	ENOG4105DQ4	alcohol dehydrogenase
F6A13_05010	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
F6A13_05015	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
F6A13_05020	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
F6A13_05025	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
F6A13_05030	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
F6A13_05040	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
F6A13_05075	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
F6A13_05080	ENOG4108MTB	glycosyl transferase family
F6A13_05085	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
F6A13_05090	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
F6A13_05095	ENOG4108IFG	nitrite reductase, (NAD(P)H)
F6A13_05115	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
F6A13_05120	ENOG4105K78	MarR family Transcriptional regulator
F6A13_05135	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
F6A13_05140	ENOG4105CW7	secretion protein, HlyD family
F6A13_05150	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F6A13_05155	ENOG4107F9Y	LysR family transcriptional regulator
F6A13_05205	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
F6A13_05215	ENOG4105DR4	Methyltransferase
F6A13_05220	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
F6A13_05225	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F6A13_05230	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
F6A13_05240	ENOG4105CQC	Prephenate dehydratase
F6A13_05245	ENOG4105CIH	Imidazole acetol-phosphate transaminase
F6A13_05250	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
F6A13_05260	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
F6A13_05265	ENOG4105CAT	Cytidine monophosphate kinase
F6A13_05270	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
F6A13_05275	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F6A13_05280	ENOG4105CFV	Tetratricopeptide repeat protein
F6A13_05285	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
F6A13_05290	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
F6A13_05295	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
F6A13_05300	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
F6A13_05305	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
F6A13_05310	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
F6A13_05330	ENOG4105EIN	peptidylprolyl cis-trans isomerase
F6A13_05360	ENOG41075W9	High frequency lysogenization protein HflD homolog
F6A13_05365	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
F6A13_05370	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
F6A13_05375	ENOG4105PW4	Sugar fermentation stimulation protein homolog
F6A13_05380	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
F6A13_05385	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
F6A13_05390	ENOG4108ZAI	phosphatidylglycerophosphatase a
F6A13_05395	ENOG4105CEV	competence damage-inducible protein
F6A13_05400	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
F6A13_05405	ENOG4105Y3E	Modulates RecA activity (By similarity)
F6A13_05410	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
F6A13_05445	ENOG4105E4C	Lytic transglycosylase catalytic
F6A13_05450	ENOG4105C0D	helicase
F6A13_05455	ENOG4106ECQ	phosphomannomutase
F6A13_05465	ENOG4105C5H	ABC transporter
F6A13_05470	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
F6A13_05480	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
F6A13_05485	ENOG4107RGH	Aldehyde dehydrogenase
F6A13_05495	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
F6A13_05500	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F6A13_05510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F6A13_05515	ENOG4106CJB	Phospholipase Carboxylesterase
F6A13_05520	ENOG4107QN2	dihydrolipoyl dehydrogenase
F6A13_05525	ENOG4105DJ9	glucan biosynthesis protein
F6A13_05535	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
F6A13_05545	ENOG4105M08	Membrane
F6A13_05555	ENOG4105ERU	peptidase
F6A13_05560	ENOG4105M00	molybdopterin converting factor, subunit 1
F6A13_05565	ENOG4108ZAF	Molybdopterin
F6A13_05570	ENOG4108VPT	UPF0234 protein
F6A13_05580	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
F6A13_05585	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
F6A13_05590	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F6A13_05595	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F6A13_05600	ENOG4105BZ1	(ABC) transporter
F6A13_05605	ENOG4108Z4U	Ferredoxin
F6A13_05610	ENOG4105D3R	alkyl hydroperoxide reductase
F6A13_05620	ENOG4105DB7	PHP domain protein
F6A13_05625	ENOG4105IPI	Membrane
F6A13_05640	ENOG4105C2N	RNA methyltransferase TrmH family group 3
F6A13_05645	ENOG4105F8V	Hydrolase, tatD family
F6A13_05650	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
F6A13_05665	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
F6A13_05675	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
F6A13_05690	ENOG4108YYC	ycei family
F6A13_05700	ENOG41090MY	MarR family Transcriptional regulator
F6A13_05705	ENOG4105EQR	Transposase IS116 IS110 IS902
F6A13_05715	ENOG4108JJ9	ABC, transporter
F6A13_05720	ENOG4108JJ8	(ABC) transporter
F6A13_05730	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
F6A13_05740	ENOG4108IYU	L-aspartate oxidase
F6A13_05745	ENOG4105EMN	RNA polymerase sigma factor
F6A13_05755	ENOG4105C0H	protease
F6A13_05760	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
F6A13_05765	ENOG4105C3F	Signal peptidase i
F6A13_05775	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
F6A13_05780	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
F6A13_05785	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
F6A13_05790	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
F6A13_05795	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
F6A13_05800	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
F6A13_05805	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
F6A13_05810	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
F6A13_05815	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
F6A13_05835	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
F6A13_05845	ENOG4105CVR	type I restriction-modification system
F6A13_05880	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
F6A13_05890	ENOG41090Y2	cytochrome C
F6A13_05895	ENOG4105PGM	cation diffusion facilitator family transporter
F6A13_05910	ENOG4105C1J	atp-dependent rna helicase
F6A13_05915	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F6A13_05920	ENOG4105BZU	Histidine kinase
F6A13_05925	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
F6A13_05930	ENOG4105C8U	phosphate abc transporter
F6A13_05935	ENOG4105E2Z	phosphate ABC transporter (Permease
F6A13_05940	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
F6A13_05945	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
F6A13_05950	ENOG4105C9X	ppx gppa phosphatase
F6A13_05960	ENOG4105CE9	30S ribosomal protein S2
F6A13_05965	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
F6A13_05970	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
F6A13_05975	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
F6A13_05980	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
F6A13_05985	ENOG4105KNE	Phosphatidate cytidylyltransferase
F6A13_05990	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
F6A13_06000	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F6A13_06010	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F6A13_06015	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
F6A13_06020	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F6A13_06025	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
F6A13_06035	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F6A13_06045	ENOG4105C0B	DNA polymerase III (alpha subunit)
F6A13_06050	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
F6A13_06055	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
F6A13_06065	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F6A13_06070	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
F6A13_06080	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F6A13_06085	ENOG4108IAB	Phoh family
F6A13_06090	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
F6A13_06125	ENOG4105NZG	Ferredoxin
F6A13_06130	ENOG41090P5	ferredoxin-like protein
F6A13_06140	ENOG4105C10	Electron transfer flavoprotein
F6A13_06145	ENOG4105BZJ	Electron transfer flavoprotein
F6A13_06175	ENOG4105M8F	Biopolymer transport protein exbD tolR
F6A13_06190	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
F6A13_06200	ENOG4108I9K	permease protein
F6A13_06240	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
F6A13_06250	ENOG410605C	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
F6A13_06260	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
F6A13_06265	ENOG4105C3J	Cysteine desulfurase
F6A13_06270	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
F6A13_06275	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
F6A13_06285	ENOG4105PS4	nifq family
F6A13_06295	ENOG4105X87	nitrogen fixation
F6A13_06300	ENOG4108VQE	nitrogen fixation protein
F6A13_06305	ENOG4108UR2	Nitrogen fixation protein NifX
F6A13_06310	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
F6A13_06315	ENOG4105D0B	Nitrogenase protein alpha chain
F6A13_06325	ENOG4105U82	Ferredoxin
F6A13_06350	ENOG4108K8Z	nad( )--dinitrogen-reductase ADP-d-ribosyltransferase
F6A13_06355	ENOG41065RQ	ADP-ribosylation crystallin J1
F6A13_06360	ENOG4108JUA	Transcriptional regulator
F6A13_06365	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
F6A13_06370	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
F6A13_06375	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
F6A13_06390	ENOG4108QWQ	LRV FeS4 cluster domain protein
F6A13_06405	ENOG4105C3J	Cysteine desulfurase
F6A13_06420	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
F6A13_06425	ENOG4108ZIT	Ferredoxin, 2FE-2S
F6A13_06440	ENOG4107XWS	modD protein
F6A13_06445	ENOG4105F4R	Transcriptional regulator mode
F6A13_06450	ENOG4105C26	Dehydrogenase
F6A13_06470	ENOG4108KPW	sugar kinase
F6A13_06475	ENOG4107STW	synthase
F6A13_06480	ENOG4105Q84	sucrose synthase
F6A13_06485	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
F6A13_06500	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F6A13_06535	ENOG4106CVF	DNA replication protein
F6A13_06550	ENOG4108UUM	single-stranded DNA-binding protein
F6A13_06570	ENOG4105ECI	YeeC-like protein
F6A13_06575	ENOG4105F6A	helicase
F6A13_06585	ENOG4105D85	methylase
F6A13_06610	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F6A13_06615	ENOG4105K70	DNA-binding protein
F6A13_06785	ENOG4105YES	addiction module antidote protein
F6A13_06860	ENOG4105C0H	protease
F6A13_06865	ENOG4105MYT	Heat shock protein
F6A13_06875	ENOG4106KE4	Dehydrogenase
F6A13_06880	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
F6A13_06890	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
F6A13_06900	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
F6A13_06905	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
F6A13_06920	ENOG4105EVH	UPF0753 protein
F6A13_06925	ENOG4108TWJ	NADH dehydrogenase subunit 5
F6A13_06930	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
F6A13_06935	ENOG4105EU8	FAD linked oxidase domain protein
F6A13_06940	ENOG4105CQB	FAD linked oxidase domain protein
F6A13_06975	ENOG4105EKE	dihydroorotase
F6A13_06980	ENOG4105C01	Dihydroxy-acid dehydratase
F6A13_06985	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F6A13_06990	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
F6A13_06995	ENOG4105D2N	Aldolase
F6A13_07000	ENOG4105FAE	von Willebrand factor, type A
F6A13_07015	ENOG4107QJE	Chromosome Partitioning Protein
F6A13_07030	ENOG4105KNY	Microcompartments protein
F6A13_07035	ENOG4105KNY	Microcompartments protein
F6A13_07040	ENOG4105KNY	Microcompartments protein
F6A13_07050	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
F6A13_07065	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
F6A13_07070	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
F6A13_07140	ENOG4105BZU	Histidine kinase
F6A13_07145	ENOG4105BZU	Histidine kinase
F6A13_07155	ENOG4105BZU	Histidine kinase
F6A13_07175	ENOG4105FA0	parb-like partition protein
F6A13_07180	ENOG4107QJE	Chromosome Partitioning Protein
F6A13_07195	ENOG4108FN7	Aldo keto reductase
F6A13_07200	ENOG4105BZU	Histidine kinase
F6A13_07245	ENOG4105YES	addiction module antidote protein
F6A13_07250	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
F6A13_07275	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
F6A13_07285	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
F6A13_07310	ENOG4108PQP	glycosyl transferase group 1
F6A13_07315	ENOG4108MN8	Membrane
F6A13_07340	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
F6A13_07345	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
F6A13_07360	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
F6A13_07365	ENOG4105DJ0	Poly(A) Polymerase
F6A13_07375	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F6A13_07380	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F6A13_07385	ENOG4107QTZ	amino acid
F6A13_07390	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
F6A13_07395	ENOG4105EGS	Mechanosensitive ion channel
F6A13_07410	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
F6A13_07415	ENOG4108Z4T	Peptidase M50
F6A13_07420	ENOG4105C31	Tryptophanyl-tRNA synthetase
F6A13_07425	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
F6A13_07430	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
F6A13_07435	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
F6A13_07440	ENOG4105FE9	pseudouridine synthase
F6A13_07445	ENOG4105CSM	endonuclease III
F6A13_07460	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F6A13_07500	ENOG4105DE4	1-phosphofructokinase
F6A13_07505	ENOG4107QYA	phosphate
F6A13_07510	ENOG4105C54	Major Facilitator superfamily
F6A13_07515	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
F6A13_07530	ENOG4108JYK	Dehydrogenase
F6A13_07540	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
F6A13_07560	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
F6A13_07565	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
F6A13_07580	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F6A13_07585	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
F6A13_07590	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
F6A13_07600	ENOG4105K4H	Nlp p60 protein
F6A13_07645	ENOG4107QTH	restriction modification system DNA specificity domain
F6A13_07680	ENOG4105EV9	Alpha Beta Hydrolase
F6A13_07695	ENOG41080VW	acetyltransferase
F6A13_07785	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
F6A13_07800	ENOG4105C0B	DNA polymerase III (alpha subunit)
F6A13_07810	ENOG4105CD8	aminopeptidase N
F6A13_07825	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
F6A13_07830	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
F6A13_07835	ENOG4105BZS	acriflavin resistance protein
F6A13_07840	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
F6A13_07855	ENOG4108UHJ	MAF-like protein
F6A13_07860	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
F6A13_07865	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
F6A13_07870	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
F6A13_07875	ENOG4107QJR	hflk protein
F6A13_07880	ENOG4105EPW	hflc protein
F6A13_07885	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
F6A13_07905	ENOG4105CSR	polyphosphate kinase 2
F6A13_07910	ENOG4107QN2	dihydrolipoyl dehydrogenase
F6A13_07915	ENOG4105CEV	competence damage-inducible protein
F6A13_07920	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
F6A13_07925	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
F6A13_07935	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
F6A13_07940	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
F6A13_07955	ENOG41082GS	50S ribosomal protein L32
F6A13_07960	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
F6A13_07965	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
F6A13_07970	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
F6A13_07975	ENOG4105CHR	reductase
F6A13_07980	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
F6A13_07985	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F6A13_07995	ENOG4105HHA	aminodeoxychorismate lyase
F6A13_08000	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
F6A13_08005	ENOG4107QRG	dna polymerase iii
F6A13_08025	ENOG4107QMP	dna polymerase iii subunits gamma and tau
F6A13_08030	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
F6A13_08035	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
F6A13_08045	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
F6A13_08050	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
F6A13_08060	ENOG4105K8N	protein family UPF0079, ATPase
F6A13_08065	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
F6A13_08070	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
F6A13_08075	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
F6A13_08080	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
F6A13_08090	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
F6A13_08095	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
F6A13_08100	ENOG4105CUT	histidyl-tRNA synthetase
F6A13_08115	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
F6A13_08135	ENOG4105C8U	phosphate abc transporter
F6A13_08155	ENOG4105EJ9	Membrane
F6A13_08240	ENOG4108IJF	Heavy metal efflux pump, CzcA
F6A13_08255	ENOG4108V1U	phospholipid-binding protein
F6A13_08260	ENOG4108Z4U	Ferredoxin
F6A13_08280	ENOG4105D03	DNA-3-methyladenine glycosylase II
F6A13_08285	ENOG4105K64	Glycosyl transferase, family 2
F6A13_08315	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
F6A13_08340	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F6A13_08350	ENOG4105CFU	surface antigen
F6A13_08370	ENOG4105W2Z	cytochrome C, class I
F6A13_08395	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
F6A13_08405	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F6A13_08410	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F6A13_08420	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
F6A13_08425	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
F6A13_08430	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
F6A13_08435	ENOG4105CTB	Polyprenyl synthetase
F6A13_08445	ENOG4105EU0	Major facilitator Superfamily
F6A13_08455	ENOG41080RH	Thioredoxin
F6A13_08460	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
F6A13_08465	ENOG4105DZG	Dehydrogenase
F6A13_08475	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
F6A13_08480	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
F6A13_08490	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
F6A13_08495	ENOG4105EW9	transcriptional regulator AsnC family
F6A13_08515	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
F6A13_08575	ENOG41060GW	
F6A13_08585	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
F6A13_08620	ENOG4105BZ1	(ABC) transporter
F6A13_08640	ENOG4108J5G	6-phosphogluconate dehydrogenase
F6A13_08645	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
F6A13_08650	ENOG41080HT	Transcriptional regulator, arsr family
F6A13_08655	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F6A13_08665	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F6A13_08670	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F6A13_08675	ENOG4105DHQ	Histidine kinase
F6A13_08680	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
F6A13_08780	ENOG41067CW	
F6A13_08860	ENOG41082AG	Plasmid maintenance system antidote protein
F6A13_08875	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F6A13_08880	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F6A13_08885	ENOG4105VIE	preprotein translocase, subunit YajC
F6A13_08890	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
F6A13_08895	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
F6A13_08900	ENOG4105C37	(CBS) domain
F6A13_08910	ENOG4105C28	cystathionine
F6A13_08915	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
F6A13_08925	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
F6A13_08930	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
F6A13_08935	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
F6A13_08940	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
F6A13_08945	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
F6A13_08950	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
F6A13_08960	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
F6A13_08965	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
F6A13_08970	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
F6A13_08975	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
F6A13_08980	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
F6A13_08985	ENOG4105N82	Endonuclease
F6A13_08990	ENOG4105D07	Signal peptide peptidase, SppA
F6A13_09025	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F6A13_09070	ENOG41089UC	methyltransferase, type 11
F6A13_09085	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
F6A13_09090	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
F6A13_09095	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
F6A13_09110	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F6A13_09130	ENOG410901P	UPF0249 protein
F6A13_09150	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
F6A13_09160	ENOG4105FE1	phytoene synthase
F6A13_09165	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
F6A13_09170	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
F6A13_09185	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
F6A13_09205	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
F6A13_09220	ENOG4105D48	metallophosphoesterase
F6A13_09225	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
F6A13_09245	ENOG4105CJN	penicillin-binding protein
F6A13_09250	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
F6A13_09255	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
F6A13_09260	ENOG4105C3G	gtp-binding protein
F6A13_09265	ENOG4108JCI	Transcriptional regulator
F6A13_09270	ENOG4108JPZ	Monovalent cation H antiporter subunit D
F6A13_09275	ENOG4107TDF	Formate hydrogenlyase subunit 4
F6A13_09285	ENOG4108JPZ	Monovalent cation H antiporter subunit D
F6A13_09290	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F6A13_09295	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F6A13_09300	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
F6A13_09315	ENOG4105DUM	transcriptional regulator, lysR family
F6A13_09320	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
F6A13_09330	ENOG4107BJW	polysaccharide deacetylase
F6A13_09340	ENOG4107QK9	Beta-lactamase
F6A13_09345	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
F6A13_09355	ENOG4105I08	Pseudouridine synthase
F6A13_09360	ENOG4105DWY	Agmatine deiminase
F6A13_09365	ENOG4105DB1	molybdopterin oxidoreductase
F6A13_09370	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
F6A13_09395	ENOG4105C4R	Atp-dependent dna helicase
F6A13_09400	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
F6A13_09405	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F6A13_09410	ENOG4105E0C	molybdate abc transporter
F6A13_09420	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
F6A13_09425	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F6A13_09430	ENOG41087PB	Frataxin-like domain
F6A13_09450	ENOG4108M8S	permease YjgP YjgQ family protein
F6A13_09455	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
F6A13_09470	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
F6A13_09475	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
F6A13_09480	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
F6A13_09495	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
F6A13_09500	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F6A13_09515	ENOG4105KAF	membrAne
F6A13_09535	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F6A13_09540	ENOG4105EI2	Pseudouridine synthase
F6A13_09545	ENOG4107QQB	Ribonuclease E
F6A13_09550	ENOG4105C8N	cysteinyl-tRNA synthetase
F6A13_09555	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
F6A13_09560	ENOG4108JQC	penicillin-binding protein 1A
F6A13_09575	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
F6A13_09580	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
F6A13_09585	ENOG4105C08	Histidine kinase
F6A13_09595	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
F6A13_09600	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
F6A13_09605	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
F6A13_09610	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F6A13_09620	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
F6A13_09690	ENOG4105DC1	bifunctional purine biosynthesis protein purh
F6A13_09695	ENOG4105C12	Phosphoribosylglycinamide synthetase
F6A13_09700	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F6A13_09705	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
F6A13_09710	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
F6A13_09730	ENOG4105M8F	Biopolymer transport protein exbD tolR
F6A13_09775	ENOG4105C54	Major Facilitator superfamily
F6A13_09780	ENOG410902C	phosphohistidine phosphatase, SixA
F6A13_09795	ENOG4105E0F	Histidine kinase
F6A13_09800	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
F6A13_09805	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
F6A13_09810	ENOG4108M8W	Monooxygenase
F6A13_09825	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
F6A13_09840	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
F6A13_09845	ENOG4105CPW	cytochrome b561
F6A13_09855	ENOG4105D94	Major Facilitator Superfamily
F6A13_09860	ENOG4106NZI	LysR family Transcriptional regulator
F6A13_09870	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F6A13_09875	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
F6A13_09880	ENOG4105C98	muts2 protein
F6A13_09890	ENOG4105VCC	30S ribosomal protein S21
F6A13_09895	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F6A13_09900	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
F6A13_09905	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
F6A13_09920	ENOG4105CSA	Coproporphyrinogen iii oxidase
F6A13_09935	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F6A13_09940	ENOG4105DZ1	carboxypeptidase
F6A13_10010	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
F6A13_10025	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
F6A13_10035	ENOG4105CR8	Transcriptional regulator
F6A13_10040	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
F6A13_10090	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
F6A13_10095	ENOG4107QZ7	Cellulose synthase catalytic subunit
F6A13_10100	ENOG4107EEX	Cellulose synthase regulator protein
F6A13_10110	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
F6A13_10115	ENOG4105BZU	Histidine kinase
F6A13_10145	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
F6A13_10155	ENOG4105C8V	SAICAR synthetase
F6A13_10170	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F6A13_10180	ENOG4108UT2	hemolysin iii
F6A13_10185	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
F6A13_10195	ENOG4105VW4	glutaredoxin 3
F6A13_10200	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
F6A13_10210	ENOG4105BZS	acriflavin resistance protein
F6A13_10215	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
F6A13_10225	ENOG41080HT	Transcriptional regulator, arsr family
F6A13_10235	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
F6A13_10250	ENOG4105CUZ	uba thif-type nad fad binding protein
F6A13_10255	ENOG4105F8V	Hydrolase, tatD family
F6A13_10260	ENOG4105D0A	hydroxylase
F6A13_10265	ENOG4105D0A	hydroxylase
F6A13_10270	ENOG4105W0Z	cytoplasmic protein
F6A13_10275	ENOG4105C0P	Mg chelatase subunit ChlI
F6A13_10310	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F6A13_10315	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F6A13_10370	ENOG4108HYG	acetyltransferase
F6A13_10375	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F6A13_10420	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F6A13_10450	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F6A13_10490	ENOG41090MY	MarR family Transcriptional regulator
F6A13_10500	ENOG4108YYC	ycei family
F6A13_10530	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F6A13_10535	ENOG4105K70	DNA-binding protein
F6A13_10550	ENOG41082CH	UPF0145 protein
F6A13_10555	ENOG4105C54	Major Facilitator superfamily
F6A13_10570	ENOG4105E02	MotA TolQ exbB proton channel
F6A13_10575	ENOG4105M8F	Biopolymer transport protein exbD tolR
F6A13_10635	ENOG4108UXE	Protein tyrosine phosphatase
F6A13_10650	ENOG4105DDK	oxidoreductase, beta subunit
F6A13_10670	ENOG4108303	d-xylulose 5-phosphate d-fructose 6-phosphate phosphoketolase
F6A13_10685	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
F6A13_10700	ENOG4108MN8	Membrane
F6A13_10705	ENOG4105KVH	Transcriptional regulator
F6A13_10710	ENOG4108K3A	Glutathione S-transferase
F6A13_10785	ENOG4105PGM	cation diffusion facilitator family transporter
F6A13_10800	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
F6A13_10835	ENOG4108IJF	Heavy metal efflux pump, CzcA
F6A13_10900	ENOG4105C59	p-type ATPase
F6A13_10910	ENOG4105W2Z	cytochrome C, class I
F6A13_10930	ENOG4107QTZ	amino acid
F6A13_10950	ENOG4108YZA	Nitrogen regulatory protein pii
F6A13_10960	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
F6A13_10965	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F6A13_10970	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
F6A13_11005	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
F6A13_11010	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
F6A13_11015	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
F6A13_11025	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
F6A13_11040	ENOG4108RGV	mercury transport protein MerC
F6A13_11045	ENOG4107QN2	dihydrolipoyl dehydrogenase
F6A13_11185	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
F6A13_11195	ENOG41072GX	Peptidase M22 Glycoprotease
F6A13_11200	ENOG4105DVT	helicase
F6A13_11215	ENOG4105K4H	Nlp p60 protein
F6A13_11245	ENOG4108Z86	Glutamine amidotransferase
F6A13_11250	ENOG4105DQR	SNARE associated Golgi
F6A13_11265	ENOG4105DUM	transcriptional regulator, lysR family
F6A13_11280	ENOG4105DGU	Histone deacetylase
F6A13_11285	ENOG4105FAE	von Willebrand factor, type A
F6A13_11330	ENOG4107QZT	geranylgeranyl reductase
F6A13_11335	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
F6A13_11345	ENOG4105PHD	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
F6A13_11355	ENOG4105RQ5	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
F6A13_11360	ENOG41086B8	CoB-CoM heterodisulfide reductase
F6A13_11375	ENOG4105EWK	phytoene
F6A13_11390	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
F6A13_11395	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
F6A13_11400	ENOG41082J7	Rhodanese domain protein
F6A13_11405	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F6A13_11415	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F6A13_11420	ENOG4105DFF	Rod shape-determining protein mreb
F6A13_11425	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
F6A13_11435	ENOG4105CJN	penicillin-binding protein
F6A13_11440	ENOG4105CNI	cell division protein FtsW
F6A13_11445	ENOG4105DZ1	carboxypeptidase
F6A13_11455	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
F6A13_11460	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
F6A13_11510	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
F6A13_11515	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
F6A13_11525	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F6A13_11545	ENOG4105WPN	DNA integration recombination invertion protein
F6A13_11575	ENOG4108K3A	Glutathione S-transferase
F6A13_11580	ENOG4105KVH	Transcriptional regulator
F6A13_11585	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
F6A13_11590	ENOG4108JUA	Transcriptional regulator
F6A13_11635	ENOG4105CZX	twitching motility protein
F6A13_11695	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
F6A13_11700	ENOG4105XMH	SpoVT AbrB domain protein
F6A13_11710	ENOG4105EKQ	RNA-directed DNA polymerase
F6A13_11725	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
F6A13_11735	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F6A13_11765	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
F6A13_11770	ENOG4108IJF	Heavy metal efflux pump, CzcA
F6A13_11975	ENOG4105D29	Helix-turn-helix type 11 domain protein
F6A13_12065	ENOG4106CVF	DNA replication protein
F6A13_12090	ENOG4105RT5	Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation
F6A13_12095	ENOG4105WJ3	XRE family Transcriptional regulator
F6A13_12160	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F6A13_12165	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
F6A13_12170	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
F6A13_12175	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
F6A13_12180	ENOG41082NX	50s ribosomal protein l35
F6A13_12185	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
F6A13_12190	ENOG4105C22	threonyL-tRNA synthetase
F6A13_12200	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F6A13_12205	ENOG4105C8S	subunit m
F6A13_12215	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F6A13_12220	ENOG4105DF2	NADH dehydrogenase subunit j
F6A13_12225	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F6A13_12230	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
F6A13_12240	ENOG4107QIZ	NADH dehydrogenase
F6A13_12250	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F6A13_12255	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F6A13_12260	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F6A13_12265	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F6A13_12280	ENOG4105CP7	Triose-phosphate isomerase
F6A13_12285	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
F6A13_12290	ENOG4105EEI	dihydropteroate synthase
F6A13_12295	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F6A13_12300	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
F6A13_12305	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F6A13_12310	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F6A13_12390	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
F6A13_12400	ENOG4105EQR	Transposase IS116 IS110 IS902
F6A13_12430	ENOG4105DHP	deoxycytidine triphosphate deaminase
F6A13_12445	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
F6A13_12450	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
F6A13_12455	ENOG4105CFG	Acts as a chaperone (By similarity)
F6A13_12460	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F6A13_12465	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
F6A13_12470	ENOG4105W0E	50S ribosomal protein L33
F6A13_12475	ENOG4105KDC	50s ribosomal protein l28
F6A13_12480	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
F6A13_12485	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
F6A13_12490	ENOG4105C9Q	fumarate hydratase class II
F6A13_12495	ENOG4105DPN	Oligoendopeptidase f
F6A13_12515	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
F6A13_12520	ENOG4105CY0	Metallo-Beta-Lactamase
F6A13_12530	ENOG4105CSM	endonuclease III
F6A13_12565	ENOG4108JJA	ABC, transporter
F6A13_12575	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F6A13_12670	ENOG4107RDJ	Sulfotransferase
F6A13_12700	ENOG4106RZ4	Peptidase U32
F6A13_12705	ENOG4105CFP	Peptidase U32
F6A13_12725	ENOG41090Y2	cytochrome C
F6A13_12730	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
F6A13_12735	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F6A13_12740	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F6A13_12745	ENOG4105EIX	cytochrome c1
F6A13_12770	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
F6A13_12775	ENOG4105HBR	Rna-binding protein
F6A13_12780	ENOG4105NWN	ApaG protein
F6A13_12785	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F6A13_12805	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
F6A13_12815	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F6A13_12820	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
F6A13_12825	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
F6A13_12835	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F6A13_12840	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
F6A13_12845	ENOG4105CAK	Cell division ATP-binding protein ftsE
F6A13_12850	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
F6A13_12855	ENOG4106H78	methyltransferase
F6A13_12860	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
F6A13_12865	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
F6A13_12870	ENOG410890F	Dynamin family
F6A13_12875	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
F6A13_12880	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
F6A13_12885	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
F6A13_12890	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
F6A13_12895	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
F6A13_12900	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
F6A13_12905	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
F6A13_12915	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
F6A13_12940	ENOG4105EN6	Membrane
F6A13_12985	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
F6A13_12990	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
F6A13_13055	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
F6A13_13090	ENOG410856B	UPF0235 protein
F6A13_13115	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
F6A13_13125	ENOG4105YES	addiction module antidote protein
F6A13_13145	ENOG4105E2V	Glycosyltransferase 36
F6A13_13180	ENOG4107RAQ	aminopeptidase
F6A13_13190	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
F6A13_13195	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
F6A13_13200	ENOG4105CDU	Replicative dna helicase
F6A13_13205	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
F6A13_13220	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
F6A13_13225	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
F6A13_13230	ENOG4105C0X	amino acid
F6A13_13240	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
F6A13_13260	ENOG4105C6T	cysteine synthase
F6A13_13280	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
F6A13_13285	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
F6A13_13295	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
F6A13_13300	ENOG4105DKQ	ROK family
F6A13_13305	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
F6A13_13310	ENOG4106BRA	Membrane
F6A13_13320	ENOG4108UUM	single-stranded DNA-binding protein
F6A13_13325	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
F6A13_13335	ENOG4107QR8	Thioredoxin
F6A13_13340	ENOG4105C0H	protease
F6A13_13345	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F6A13_13355	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
F6A13_13360	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
F6A13_13365	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
F6A13_13370	ENOG4105K5M	30s ribosomal protein S16
F6A13_13375	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F6A13_13435	ENOG4108UXE	Protein tyrosine phosphatase
F6A13_13445	ENOG4105CJ1	ABC, transporter
F6A13_13450	ENOG4107QWP	ABC-2 type transporter
F6A13_13455	ENOG4107QWP	ABC-2 type transporter
F6A13_13480	ENOG4105RQ5	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
F6A13_13510	ENOG4108ZG0	Ompa motb domain protein
F6A13_13580	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
F6A13_13590	ENOG4105C5H	ABC transporter
F6A13_13605	ENOG4105CJN	penicillin-binding protein
F6A13_13625	ENOG4105EAH	synthase
F6A13_13635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F6A13_13640	ENOG4105CUX	Signal transduction histidine kinase
F6A13_13665	ENOG4105CYN	Serine protein kinase
F6A13_13670	ENOG4105BZU	Histidine kinase
F6A13_13675	ENOG4106AKX	UPF0229 protein
F6A13_13680	ENOG4105ED1	spovr family
F6A13_13690	ENOG4108YZA	Nitrogen regulatory protein pii
F6A13_13695	ENOG4105BZU	Histidine kinase
F6A13_13725	ENOG4107SVH	Potassium channel protein
F6A13_13730	ENOG4105DZ1	carboxypeptidase
F6A13_13735	ENOG4105C89	phosphohexose isomerase
F6A13_13750	ENOG4105WMR	Protein CrcB homolog
F6A13_13765	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
F6A13_13775	ENOG4105DSY	exodeoxyribonuclease V, gamma
F6A13_13780	ENOG4107QKA	exodeoxyribonuclease V beta
F6A13_13785	ENOG4107QYX	exodeoxyribonuclease v alpha
F6A13_13820	ENOG4105E0X	reductase
F6A13_13825	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
F6A13_13835	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
F6A13_13845	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
F6A13_13860	ENOG4108Z03	MAF-like protein
F6A13_13865	ENOG4105C03	ribonuclease
F6A13_13870	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F6A13_13880	ENOG4107WP9	Histidine kinase
F6A13_13890	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
F6A13_13900	ENOG4107U8J	Export protein
F6A13_13910	ENOG4108RDB	capsule polysaccharide export inner-membrane protein
F6A13_13930	ENOG4105CGN	Glycosyl transferase (Group 1
F6A13_13970	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
F6A13_13980	ENOG4105CMR	udp-glucose 4-epimerase
F6A13_14095	ENOG4105EY8	ABC transporter
F6A13_14110	ENOG4108TJN	glycosyl transferase group 1
F6A13_14115	ENOG4105BZ1	(ABC) transporter
F6A13_14145	ENOG4105C3U	ABC transporter
F6A13_14150	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F6A13_14180	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
F6A13_14185	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
F6A13_14200	ENOG4105E02	MotA TolQ exbB proton channel
F6A13_14205	ENOG4105M15	transport protein ExbD
F6A13_14240	ENOG41084CK	capsule polysaccharide
F6A13_14255	ENOG4105CEN	a g-specific adenine glycosylase
F6A13_14265	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
F6A13_14270	ENOG41080Z8	PHOSPHOCARRIER protein
F6A13_14280	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
F6A13_14285	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
F6A13_14290	ENOG4105DM4	PTS System
F6A13_14295	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
F6A13_14300	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F6A13_14305	ENOG4108IUZ	ABC transporter
F6A13_14310	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
F6A13_14320	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
F6A13_14325	ENOG4105C2X	Arabinose 5-phosphate isomerase
F6A13_14340	ENOG4108S0S	Nucleotidyl transferase
F6A13_14345	ENOG4105EHM	Aminoglycoside phosphotransferase
F6A13_14350	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
F6A13_14355	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
F6A13_14360	ENOG4105E3A	(ABC) transporter
F6A13_14370	ENOG4105M2J	Glutaredoxin
F6A13_14375	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
F6A13_14380	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
F6A13_14385	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
F6A13_14390	ENOG4105CIH	Imidazole acetol-phosphate transaminase
F6A13_14395	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
F6A13_14400	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
F6A13_14405	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
F6A13_14410	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
F6A13_14420	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
F6A13_14425	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
F6A13_14430	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
F6A13_14435	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
F6A13_14440	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
F6A13_14450	ENOG4105FAE	von Willebrand factor, type A
F6A13_14455	ENOG4105K70	DNA-binding protein
F6A13_14465	ENOG4105CD3	dihydroorotase
F6A13_14470	ENOG4105CXT	aspartate transcarbamylase
F6A13_14475	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
F6A13_14480	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
F6A13_14485	ENOG4108UJU	UPF0301 protein
F6A13_14490	ENOG4105D7Z	glutathione synthase
F6A13_14500	ENOG4105BZN	citrate synthase
F6A13_14505	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
F6A13_14510	ENOG4107QN2	dihydrolipoyl dehydrogenase
F6A13_14535	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
F6A13_14540	ENOG4108UJD	30S ribosomal protein S9
F6A13_14545	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
F6A13_14585	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
F6A13_14590	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
F6A13_14595	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
F6A13_14605	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
F6A13_14610	ENOG4107SVH	Potassium channel protein
F6A13_14615	ENOG4105C2M	dna polymerase I
F6A13_14630	ENOG4105CUV	Homoserine Kinase
F6A13_14645	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
F6A13_14650	ENOG4105C4R	Atp-dependent dna helicase
F6A13_14670	ENOG4105DCG	PHP domain protein
F6A13_14675	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
F6A13_14680	ENOG4105C5I	Dehydrogenase
F6A13_14690	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
F6A13_14695	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
F6A13_14700	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
F6A13_14705	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
F6A13_14710	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
F6A13_14715	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
F6A13_14720	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F6A13_14725	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F6A13_14730	ENOG41082T0	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F6A13_14745	ENOG4105FA0	parb-like partition protein
F6A13_14750	ENOG4107QJE	Chromosome Partitioning Protein
F6A13_14755	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
F6A13_14760	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
F6A13_14775	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
F6A13_14805	ENOG4105CS1	NAD(P)H quinone oxidoreductase
F6A13_14810	ENOG4105EUB	pirin domain protein
F6A13_14845	ENOG4105CVR	type I restriction-modification system
F6A13_14875	ENOG4105EKX	Restriction modification system DNA (Specificity
F6A13_14885	ENOG4105DZR	Type I site-specific deoxyribonuclease
F6A13_14905	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
F6A13_14910	ENOG4105CYM	Glutathione S-transferase
F6A13_14925	ENOG41082CH	UPF0145 protein
F6A13_14940	ENOG4105CJ1	ABC, transporter
F6A13_14955	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
F6A13_14960	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
F6A13_14970	ENOG4105DK0	Indole-3-glycerol phosphate synthase
F6A13_14975	ENOG4108I0Q	anthranilate phosphoribosyltransferase
F6A13_14980	ENOG4105DDQ	anthranilate synthase
F6A13_14985	ENOG4105CRQ	synthase (Component I)
F6A13_14990	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F6A13_14995	ENOG4105DJV	ribulose-phosphate 3-epimerase
F6A13_15000	ENOG4105D2N	Aldolase
F6A13_15005	ENOG4105CA9	Pyruvate kinase
F6A13_15010	ENOG4105BZA	Phosphoglycerate kinase
F6A13_15015	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
F6A13_15020	ENOG4105CV1	Transketolase (EC 2.2.1.1)
F6A13_15030	ENOG4105ECY	inositol monophosphatase
F6A13_15040	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
F6A13_15045	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
F6A13_15055	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
F6A13_15070	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
F6A13_15125	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
F6A13_15130	ENOG4105E0F	Histidine kinase
F6A13_15140	ENOG4105CH7	arginosuccinase
F6A13_15150	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
F6A13_15170	ENOG4105E3S	small subunit
F6A13_15180	ENOG4105DF6	Fe-S oxidoreductase
F6A13_15185	ENOG4105DPX	Hydrogenase, large subunit
F6A13_15190	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
F6A13_15195	ENOG4107RSS	Hydrogenase accessory protein HypB
F6A13_15200	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
F6A13_15210	ENOG4108DMA	Nad-dependent epimerase dehydratase
F6A13_15215	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
F6A13_15220	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
F6A13_15225	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
F6A13_15245	ENOG4105D52	delta-aminolevulinic acid dehydratase
F6A13_15255	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
F6A13_15265	ENOG4107ZUX	Histidine triad (HIT) protein
F6A13_15270	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
F6A13_15275	ENOG4107S5G	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
F6A13_15280	ENOG4105DWF	phosphomethylpyrimidine kinase
F6A13_15285	ENOG4107FW0	short-chain dehydrogenase reductase