locus-tag	class	description
GT370_00060	COG1595	DNA-templated transcription, initiation
GT370_00085	COG1131	(ABC) transporter
GT370_00090	COG0842	Transport permease protein
GT370_00095	COG0842	Transport permease protein
GT370_00105	COG0798	PFAM Bile acid sodium symporter
GT370_00115	COG1393	Belongs to the ArsC family
GT370_00175	COG5489	Protein of unknown function (DUF736)
GT370_00265	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GT370_00265	COG0617	tRNA 3'-terminal CCA addition
GT370_00265	COG0517	IMP dehydrogenase activity
GT370_00305	COG4566	intracellular signal transduction
GT370_00330	COG3039	Transposase
GT370_00385	COG0673	inositol 2-dehydrogenase activity
GT370_00485	COG1349	DNA-binding transcription factor activity
GT370_00490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT370_00495	COG3684	Belongs to the aldolase LacD family
GT370_00500	COG1063	alcohol dehydrogenase
GT370_00520	COG3046	protein related to deoxyribodipyrimidine photolyase
GT370_00525	COG3046	protein related to deoxyribodipyrimidine photolyase
GT370_00550	COG0745	RESPONSE REGULATOR receiver
GT370_00555	COG4303	Ethanolamine ammonia lyase large subunit
GT370_00560	COG4302	ethanolamine ammonia-lyase activity
GT370_00565	COG0038	chloride channel
GT370_00575	COG0583	DNA-binding transcription factor activity
GT370_00600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT370_00605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT370_00610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GT370_00615	COG0443	Heat shock 70 kDa protein
GT370_00620	COG0484	heat shock protein binding
GT370_00650	COG3436	PFAM IS66 Orf2 family protein
GT370_00660	COG0625	glutathione transferase activity
GT370_00680	COG1959	2 iron, 2 sulfur cluster binding
GT370_00685	COG0633	Ferredoxin
GT370_00685	COG0543	2 iron, 2 sulfur cluster binding
GT370_00695	COG1151	hydroxylamine reductase activity
GT370_00700	COG1151	hydroxylamine reductase activity
GT370_00725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT370_00735	COG2814	Major facilitator Superfamily
GT370_00745	COG0745	RESPONSE REGULATOR receiver
GT370_00750	COG0642	Histidine kinase
GT370_00755	COG1802	Transcriptional regulator
GT370_00770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT370_00775	COG0179	Fumarylacetoacetate (FAA) hydrolase
GT370_00795	COG2080	2 iron, 2 sulfur cluster binding
GT370_00800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GT370_00820	COG0640	Transcriptional regulator
GT370_00825	COG0450	alkyl hydroperoxide reductase
GT370_00855	COG0730	response to heat
GT370_00885	COG3842	ATPase activity
GT370_00890	COG0246	Mannitol dehydrogenase
GT370_00900	COG1070	Carbohydrate kinase
GT370_00950	COG0246	Mannitol dehydrogenase
GT370_00960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT370_00990	COG2072	flavoprotein involved in K transport
GT370_01000	COG0656	L-ascorbic acid biosynthetic process
GT370_01010	COG3706	GGDEF domain
GT370_01015	COG2205	protein histidine kinase activity
GT370_01025	COG0477	Major facilitator Superfamily
GT370_01030	COG0583	DNA-binding transcription factor activity
GT370_01035	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_01050	COG1230	cation diffusion facilitator family transporter
GT370_01065	COG0481	GTPase activity
GT370_01105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GT370_01110	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GT370_01115	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GT370_01125	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GT370_01140	COG2814	Major facilitator Superfamily
GT370_01155	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GT370_01155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GT370_01190	COG0626	cystathionine gamma-synthase activity
GT370_01195	COG2897	thiosulfate sulfurtransferase activity
GT370_01205	COG0628	permease
GT370_01210	COG0792	nuclease activity
GT370_01230	COG0667	Aldo Keto reductase
GT370_01245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GT370_01250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GT370_01265	COG0358	DNA primase activity
GT370_01285	COG0564	pseudouridine synthase activity
GT370_01320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT370_01325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT370_01335	COG2226	methyltransferase
GT370_01345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GT370_01365	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GT370_01370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GT370_01380	COG0138	bifunctional purine biosynthesis protein purh
GT370_01395	COG0438	transferase activity, transferring glycosyl groups
GT370_01405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GT370_01425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GT370_01435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GT370_01435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GT370_01445	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GT370_01495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GT370_01500	COG2885	chlorophyll binding
GT370_01515	COG0037	tRNA processing
GT370_01520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GT370_01525	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GT370_01530	COG1546	Belongs to the CinA family
GT370_01530	COG1058	Belongs to the CinA family
GT370_01540	COG0741	lytic transglycosylase activity
GT370_01540	COG0739	heme binding
GT370_01540	COG1196	nuclear chromosome segregation
GT370_01545	COG0741	lytic transglycosylase activity
GT370_01550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT370_01555	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GT370_01575	COG1758	RNA polymerase activity
GT370_01585	COG0736	holo-[acyl-carrier-protein] synthase activity
GT370_01615	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GT370_01620	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GT370_01655	COG3023	N-Acetylmuramoyl-L-alanine amidase
GT370_01665	COG2001	Belongs to the MraZ family
GT370_01695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GT370_01700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GT370_01715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GT370_01720	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GT370_01725	COG1181	Belongs to the D-alanine--D-alanine ligase family
GT370_01750	COG0148	phosphopyruvate hydratase activity
GT370_01770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GT370_01775	COG0625	glutathione transferase activity
GT370_01780	COG0406	alpha-ribazole phosphatase activity
GT370_01815	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GT370_01820	COG1278	Cold shock
GT370_01865	COG1192	Involved in chromosome partitioning
GT370_01870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GT370_01870	COG1648	precorrin-2 dehydrogenase activity
GT370_01875	COG0840	transmembrane signaling receptor activity
GT370_01890	COG0643	Histidine kinase
GT370_01890	COG2198	Histidine kinase
GT370_01895	COG0643	Histidine kinase
GT370_01895	COG2198	Histidine kinase
GT370_01900	COG0835	chemotaxis
GT370_01905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GT370_01910	COG2201	protein-glutamate methylesterase activity
GT370_01915	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GT370_01925	COG0835	chemotaxis
GT370_01930	COG2945	thiolester hydrolase activity
GT370_01935	COG1045	serine acetyltransferase
GT370_01960	COG4178	(ABC) transporter
GT370_01990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GT370_01995	COG0271	Belongs to the BolA IbaG family
GT370_02000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GT370_02005	COG0047	phosphoribosylformylglycinamidine synthase activity
GT370_02010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GT370_02020	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GT370_02025	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GT370_02055	COG1509	lysine 2,3-aminomutase activity
GT370_02060	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GT370_02080	COG1830	Aldolase
GT370_02105	COG0776	regulation of translation
GT370_02120	COG0135	phosphoribosylanthranilate isomerase activity
GT370_02125	COG0730	response to heat
GT370_02135	COG4974	Belongs to the 'phage' integrase family
GT370_02140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GT370_02175	COG1686	Belongs to the peptidase S11 family
GT370_02195	COG2824	Alkylphosphonate utilization operon protein PhnA
GT370_02215	COG2010	Cytochrome c
GT370_02215	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT370_02230	COG0457	Tetratricopeptide repeat
GT370_02245	COG5265	(ABC) transporter
GT370_02250	COG0521	Mo-molybdopterin cofactor biosynthetic process
GT370_02255	COG0741	lytic transglycosylase activity
GT370_02265	COG1573	uracil-dna glycosylase
GT370_02290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GT370_02295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GT370_02310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GT370_02315	COG1846	Transcriptional regulator
GT370_02335	COG0756	dUTP diphosphatase activity
GT370_02340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GT370_02345	COG2226	methyltransferase
GT370_02365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GT370_02370	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GT370_02375	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GT370_02400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GT370_02430	COG1923	regulation of RNA biosynthetic process
GT370_02440	COG0483	inositol monophosphate 1-phosphatase activity
GT370_02455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GT370_02480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GT370_02530	COG0596	Alpha beta hydrolase
GT370_02540	COG0745	RESPONSE REGULATOR receiver
GT370_02545	COG0745	RESPONSE REGULATOR receiver
GT370_02555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GT370_02570	COG3240	lipase activity
GT370_02575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GT370_02595	COG0019	diaminopimelate decarboxylase activity
GT370_02605	COG0165	Argininosuccinate lyase
GT370_02610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GT370_02630	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GT370_02660	COG0556	nucleotide-excision repair
GT370_02670	COG2116	formate transmembrane transporter activity
GT370_02685	COG0837	glucose binding
GT370_02690	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GT370_02740	COG4191	Histidine kinase
GT370_02740	COG0784	Response regulator, receiver
GT370_02750	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GT370_02755	COG0509	glycine decarboxylation via glycine cleavage system
GT370_02765	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GT370_02775	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GT370_02805	COG0829	nickel cation binding
GT370_02810	COG0804	urea catabolic process
GT370_02815	COG0832	Belongs to the urease beta subunit family
GT370_02815	COG0831	urea catabolic process
GT370_02820	COG0830	nickel cation binding
GT370_02830	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GT370_02835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GT370_02855	COG0159	tryptophan synthase activity
GT370_02860	COG0133	tryptophan synthase activity
GT370_02870	COG0473	3-isopropylmalate dehydrogenase activity
GT370_02900	COG0492	ferredoxin-NADP+ reductase activity
GT370_02910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GT370_02920	COG2887	Belongs to the helicase family. UvrD subfamily
GT370_02925	COG1074	ATP-dependent DNA helicase activity
GT370_02955	COG1522	sequence-specific DNA binding
GT370_02985	COG1304	FMN binding
GT370_02990	COG4213	ABC transporter substrate-binding protein
GT370_03010	COG4214	carbohydrate transport
GT370_03025	COG1940	carbohydrate kinase activity
GT370_03035	COG0363	glucosamine-6-phosphate deaminase activity
GT370_03040	COG0129	dihydroxy-acid dehydratase activity
GT370_03045	COG0800	Aldolase
GT370_03055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT370_03065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GT370_03090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GT370_03095	COG1845	cytochrome c oxidase, subunit III
GT370_03110	COG1960	acyl-CoA dehydrogenase activity
GT370_03120	COG0183	Belongs to the thiolase family
GT370_03155	COG0318	PFAM AMP-dependent synthetase and ligase
GT370_03190	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT370_03190	COG0493	'glutamate synthase
GT370_03210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT370_03215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT370_03225	COG1309	transcriptional regulator
GT370_03230	COG1024	Enoyl-CoA hydratase
GT370_03235	COG1024	Enoyl-CoA hydratase
GT370_03275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT370_03280	COG2154	pterin-4-alpha-carbinolamine dehydratase
GT370_03310	COG0483	inositol monophosphate 1-phosphatase activity
GT370_03330	COG0829	nickel cation binding
GT370_03335	COG0831	urea catabolic process
GT370_03340	COG0832	Belongs to the urease beta subunit family
GT370_03355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GT370_03375	COG4106	trans-aconitate 2-methyltransferase activity
GT370_03385	COG3842	ATPase activity
GT370_03395	COG0395	ABC-type sugar transport system, permease component
GT370_03405	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT370_03410	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT370_03425	COG2186	Transcriptional regulator
GT370_03435	COG2267	carboxylic ester hydrolase activity
GT370_03445	COG1012	belongs to the aldehyde dehydrogenase family
GT370_03460	COG1024	Enoyl-CoA hydratase
GT370_03465	COG1024	Enoyl-CoA hydratase
GT370_03510	COG1137	ATPase activity
GT370_03525	COG4214	carbohydrate transport
GT370_03555	COG2186	Transcriptional regulator
GT370_03565	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GT370_03570	COG0679	Auxin Efflux Carrier
GT370_03580	COG2226	methyltransferase
GT370_03590	COG3008	intermembrane lipid transfer
GT370_03595	COG2995	paraquat-inducible protein a
GT370_03610	COG0151	Belongs to the GarS family
GT370_03620	COG1132	(ABC) transporter
GT370_03680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GT370_03690	COG3634	alkyl hydroperoxide reductase activity
GT370_03705	COG1686	Belongs to the peptidase S11 family
GT370_03710	COG0681	Belongs to the peptidase S26 family
GT370_03720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GT370_03760	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GT370_03765	COG3739	integral membrane protein
GT370_03770	COG1185	polyribonucleotide nucleotidyltransferase activity
GT370_03775	COG0477	Major facilitator Superfamily
GT370_03790	COG1914	H( )-stimulated, divalent metal cation uptake system
GT370_03795	COG1914	H( )-stimulated, divalent metal cation uptake system
GT370_03805	COG3956	TIGRFAM MazG family protein
GT370_03810	COG0386	Belongs to the glutathione peroxidase family
GT370_03835	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GT370_03840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GT370_03870	COG3088	subunit of a heme lyase
GT370_03880	COG1138	Cytochrome C-type biogenesis protein
GT370_03885	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GT370_03895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GT370_03920	COG4221	oxidoreductase activity
GT370_03935	COG0698	ribose 5-phosphate isomerase
GT370_03940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GT370_03945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GT370_03950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT370_03950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT370_03965	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GT370_03970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GT370_03975	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GT370_03985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GT370_03990	COG0793	Belongs to the peptidase S41A family
GT370_04000	COG0557	exoribonuclease II activity
GT370_04015	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GT370_04035	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GT370_04045	COG0259	pyridoxamine-phosphate oxidase activity
GT370_04050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GT370_04070	COG5002	protein histidine kinase activity
GT370_04075	COG0069	glutamate synthase activity
GT370_04085	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GT370_04110	COG1442	glycosyl transferase family 8
GT370_04145	COG1959	2 iron, 2 sulfur cluster binding
GT370_04155	COG1538	Outer membrane efflux protein
GT370_04190	COG0438	transferase activity, transferring glycosyl groups
GT370_04195	COG0859	PFAM glycosyl transferase family 9
GT370_04220	COG0415	Belongs to the DNA photolyase family
GT370_04255	COG1960	acyl-CoA dehydrogenase activity
GT370_04260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT370_04275	COG3842	ATPase activity
GT370_04320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GT370_04330	COG0540	Belongs to the ATCase OTCase family
GT370_04350	COG0084	hydrolase, TatD family'
GT370_04355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GT370_04365	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GT370_04375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GT370_04390	COG2983	Belongs to the UPF0260 family
GT370_04410	COG3706	GGDEF domain
GT370_04430	COG0069	glutamate synthase activity
GT370_04435	COG2218	PFAM glutamate synthase alpha subunit domain protein
GT370_04440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GT370_04445	COG1064	alcohol dehydrogenase
GT370_04455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GT370_04465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GT370_04470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GT370_04495	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GT370_04505	COG0194	GDP metabolic process
GT370_04510	COG1561	YicC-like family, N-terminal region
GT370_04570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GT370_04620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GT370_04625	COG2814	Major facilitator Superfamily
GT370_04630	COG0131	Imidazoleglycerol-phosphate dehydratase
GT370_04635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GT370_04645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GT370_04650	COG0107	imidazoleglycerol-phosphate synthase activity
GT370_04655	COG0140	phosphoribosyl-ATP diphosphatase activity
GT370_04695	COG2353	YceI-like domain
GT370_04735	COG1266	CAAX protease self-immunity
GT370_04740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GT370_04745	COG0235	Class ii aldolase
GT370_04755	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
GT370_04760	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GT370_04765	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GT370_04770	COG1396	sequence-specific DNA binding
GT370_04845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GT370_04850	COG2084	Dehydrogenase
GT370_04865	COG0776	regulation of translation
GT370_04870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GT370_04875	COG0416	fatty acid biosynthetic process
GT370_04880	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GT370_04960	COG1137	ATPase activity
GT370_04970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GT370_04975	COG0024	Methionine aminopeptidase
GT370_04980	COG0114	fumarate hydratase activity
GT370_05010	COG3594	Acyltransferase
GT370_05035	COG0658	competence protein
GT370_05035	COG2333	competence protein COMEC
GT370_05095	COG4964	Belongs to the GSP D family
GT370_05180	COG0477	Major facilitator Superfamily
GT370_05200	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GT370_05205	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_05210	COG3734	2-keto-3-deoxy-galactonokinase
GT370_05215	COG0800	Aldolase
GT370_05220	COG0800	Aldolase
GT370_05280	COG2031	fatty acid transporter
GT370_05285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT370_05285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GT370_05290	COG1105	Belongs to the carbohydrate kinase PfkB family
GT370_05295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GT370_05295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT370_05305	COG0038	chloride channel
GT370_05325	COG3383	formate dehydrogenase (NAD+) activity
GT370_05355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT370_05370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GT370_05370	COG0519	Catalyzes the synthesis of GMP from XMP
GT370_05380	COG3328	transposase activity
GT370_05425	COG3846	protein secretion by the type IV secretion system
GT370_05430	COG5314	conjugation
GT370_05455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GT370_05500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT370_05510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT370_05515	COG2171	N-acyltransferase activity
GT370_05520	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GT370_05530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GT370_05535	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GT370_05550	COG1994	Peptidase M50
GT370_05555	COG1472	Belongs to the glycosyl hydrolase 3 family
GT370_05570	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GT370_05585	COG0316	Belongs to the HesB IscA family
GT370_05590	COG2151	metal-sulfur cluster biosynthetic enzyme
GT370_05600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GT370_05605	COG0719	Fe-S assembly protein
GT370_05615	COG0396	ATPase activity
GT370_05620	COG0719	Fe-S assembly protein
GT370_05625	COG1959	2 iron, 2 sulfur cluster binding
GT370_05635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GT370_05650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GT370_05660	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GT370_05675	COG1695	Transcriptional regulator
GT370_05700	COG1519	Transferase
GT370_05705	COG1519	Transferase
GT370_05750	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GT370_05755	COG3040	lipid binding
GT370_05800	COG2339	peptidase activity
GT370_05810	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GT370_05820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GT370_05835	COG1131	(ABC) transporter
GT370_05865	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GT370_05900	COG3617	BRO family, N-terminal domain
GT370_05990	COG0463	Glycosyl transferase, family 2
GT370_05990	COG1216	Glycosyl transferase, family 2
GT370_06000	COG0598	Magnesium transport protein CorA
GT370_06025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GT370_06030	COG1381	Involved in DNA repair and RecF pathway recombination
GT370_06040	COG1473	amidohydrolase
GT370_06045	COG1473	amidohydrolase
GT370_06055	COG0527	aspartate kinase activity
GT370_06085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GT370_06090	COG2890	protein-(glutamine-N5) methyltransferase activity
GT370_06110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GT370_06145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GT370_06195	COG0321	lipoyl(octanoyl) transferase activity
GT370_06210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT370_06215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT370_06235	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GT370_06255	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GT370_06275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GT370_06280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GT370_06285	COG5001	Diguanylate cyclase
GT370_06285	COG4251	negative regulation of phosphorylation
GT370_06285	COG3706	GGDEF domain
GT370_06285	COG2203	Gaf domain
GT370_06310	COG2733	membrane
GT370_06315	COG2733	membrane
GT370_06340	COG0582	viral genome integration into host DNA
GT370_06420	COG2963	transposase activity
GT370_06425	COG3436	PFAM IS66 Orf2 family protein
GT370_06430	COG2433	Pfam Transposase IS66
GT370_06435	COG3318	Belongs to the UPF0149 family
GT370_06460	COG2814	Major facilitator Superfamily
GT370_06475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT370_06530	COG0346	lactoylglutathione lyase activity
GT370_06545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GT370_06565	COG0750	zinc metalloprotease
GT370_06570	COG0750	zinc metalloprotease
GT370_06585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GT370_06590	COG0233	cytoplasmic translational termination
GT370_06595	COG0528	UMP kinase activity
GT370_06620	COG0823	Involved in the tonB-independent uptake of proteins
GT370_06655	COG0811	peptide transport
GT370_06660	COG0824	Thioesterase
GT370_06675	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GT370_06680	COG0217	transcriptional regulatory protein
GT370_06685	COG0784	Response regulator, receiver
GT370_06685	COG4191	Histidine kinase
GT370_06700	COG4133	protoheme IX ABC transporter activity
GT370_06705	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GT370_06710	COG0517	IMP dehydrogenase activity
GT370_06715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT370_06730	COG2814	Major facilitator Superfamily
GT370_06745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GT370_06755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GT370_06760	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GT370_06775	COG0583	DNA-binding transcription factor activity
GT370_06780	COG1058	Belongs to the CinA family
GT370_06780	COG1546	Belongs to the CinA family
GT370_06785	COG0494	nUDIX hydrolase
GT370_06790	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GT370_06795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GT370_06800	COG0799	negative regulation of ribosome biogenesis
GT370_06805	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GT370_06815	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GT370_06825	COG0793	Belongs to the peptidase S41A family
GT370_06830	COG1051	belongs to the nudix hydrolase family
GT370_06835	COG0412	Dienelactone hydrolase
GT370_06855	COG0776	regulation of translation
GT370_06890	COG0513	Belongs to the DEAD box helicase family
GT370_06900	COG1253	flavin adenine dinucleotide binding
GT370_06905	COG0154	amidase activity
GT370_06925	COG0668	transmembrane transport
GT370_06930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GT370_06940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GT370_06950	COG0513	Belongs to the DEAD box helicase family
GT370_06955	COG0789	Transcriptional regulator
GT370_06960	COG2217	Heavy metal translocating P-type atpase
GT370_06985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT370_07000	COG0175	sulfate reduction
GT370_07010	COG2205	protein histidine kinase activity
GT370_07020	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GT370_07025	COG0594	ribonuclease P activity
GT370_07030	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GT370_07045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GT370_07055	COG1392	Phosphate transport regulator
GT370_07060	COG2828	Protein conserved in bacteria
GT370_07075	COG1802	Transcriptional regulator
GT370_07085	COG3842	ATPase activity
GT370_07095	COG4208	sulfate ABC transporter
GT370_07110	COG1309	transcriptional regulator
GT370_07115	COG1335	isochorismatase
GT370_07315	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GT370_07320	COG3750	Belongs to the UPF0335 family
GT370_07485	COG2814	Major facilitator Superfamily
GT370_07500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GT370_07505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GT370_07510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GT370_07515	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GT370_07520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GT370_07530	COG0477	Major facilitator Superfamily
GT370_07560	COG0583	DNA-binding transcription factor activity
GT370_07585	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GT370_07590	COG1420	regulation of RNA biosynthetic process
GT370_07610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT370_07615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT370_07620	COG0174	glutamine synthetase
GT370_07630	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GT370_07635	COG1177	transmembrane transport
GT370_07645	COG3842	ATPase activity
GT370_07650	COG1917	Cupin 2, conserved barrel domain protein
GT370_07650	COG1396	sequence-specific DNA binding
GT370_07665	COG1832	CoA-binding protein
GT370_07670	COG1716	ATPase activity
GT370_07670	COG5001	Diguanylate cyclase
GT370_07715	COG0308	aminopeptidase N
GT370_07720	COG0625	glutathione transferase activity
GT370_07770	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GT370_07825	COG0457	Tetratricopeptide repeat
GT370_07840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GT370_07850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GT370_07880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT370_07890	COG0515	serine threonine protein kinase
GT370_07890	COG2815	serine threonine protein kinase
GT370_07915	COG0347	Belongs to the P(II) protein family
GT370_07940	COG2308	Evidence 4 Homologs of previously reported genes of
GT370_07950	COG1305	Transglutaminase-like
GT370_07960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GT370_07965	COG0564	pseudouridine synthase activity
GT370_08025	COG0454	-acetyltransferase
GT370_08025	COG0456	acetyltransferase
GT370_08065	COG0688	phosphatidylethanolamine metabolic process
GT370_08095	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_08110	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GT370_08115	COG0268	Binds directly to 16S ribosomal RNA
GT370_08150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GT370_08150	COG2857	Cytochrome c1
GT370_08170	COG0408	coproporphyrinogen oxidase activity
GT370_08185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GT370_08190	COG0022	dehydrogenase e1 component
GT370_08190	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT370_08195	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT370_08205	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GT370_08210	COG2867	negative regulation of translational initiation
GT370_08225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GT370_08230	COG0629	single-stranded DNA binding
GT370_08245	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GT370_08255	COG0583	DNA-binding transcription factor activity
GT370_08265	COG0235	Class ii aldolase
GT370_08275	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GT370_08280	COG2986	histidine ammonia-lyase
GT370_08285	COG1228	amidohydrolase
GT370_08295	COG2188	Transcriptional regulator
GT370_08320	COG1566	PFAM secretion protein HlyD family protein
GT370_08335	COG5328	Belongs to the UPF0262 family
GT370_08345	COG2816	NAD+ diphosphatase activity
GT370_08360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GT370_08365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GT370_08400	COG0242	peptide deformylase activity
GT370_08405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GT370_08410	COG0101	tRNA pseudouridine synthase activity
GT370_08435	COG1505	serine-type exopeptidase activity
GT370_08440	COG0038	chloride channel
GT370_08465	COG0424	maF-like protein
GT370_08480	COG0693	protein deglycase activity
GT370_08515	COG0004	ammonium transporteR
GT370_08520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT370_08540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GT370_08570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT370_08595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GT370_08640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GT370_08645	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GT370_08655	COG0392	lysyltransferase activity
GT370_08675	COG1217	gtp-binding protein TYPA
GT370_08705	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GT370_08720	COG1215	transferase activity, transferring glycosyl groups
GT370_08725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GT370_08740	COG5001	Diguanylate cyclase
GT370_08740	COG1716	ATPase activity
GT370_08795	COG0765	amino acid transport
GT370_08820	COG4598	ABC transporter
GT370_08830	COG0765	amino acid transport
GT370_08860	COG1297	OPT oligopeptide transporter protein
GT370_08865	COG1297	OPT oligopeptide transporter protein
GT370_08880	COG1054	Belongs to the UPF0176 family
GT370_08915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT370_08920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GT370_08930	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GT370_08935	COG4251	negative regulation of phosphorylation
GT370_08940	COG0784	Response regulator, receiver
GT370_08940	COG4191	Histidine kinase
GT370_08945	COG0784	Response regulator, receiver
GT370_08945	COG4191	Histidine kinase
GT370_08965	COG0028	Belongs to the TPP enzyme family
GT370_08995	COG3387	PFAM Glycoside hydrolase 15-related
GT370_09000	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GT370_09005	COG1845	cytochrome c oxidase, subunit III
GT370_09010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GT370_09015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GT370_09020	COG0640	Transcriptional regulator
GT370_09035	COG2376	Dihydroxyacetone kinase
GT370_09050	COG0583	DNA-binding transcription factor activity
GT370_09065	COG0667	Aldo Keto reductase
GT370_09080	COG3254	rhamnose metabolic process
GT370_09085	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_09095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT370_09100	COG0246	Mannitol dehydrogenase
GT370_09105	COG1063	alcohol dehydrogenase
GT370_09110	COG2721	sulfolactate sulfo-lyase activity
GT370_09115	COG1129	ABC transporter
GT370_09130	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT370_09135	COG2186	Transcriptional regulator
GT370_09155	COG4974	Belongs to the 'phage' integrase family
GT370_09175	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GT370_09180	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GT370_09235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GT370_09260	COG2186	Transcriptional regulator
GT370_09265	COG1304	FMN binding
GT370_09300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GT370_09305	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GT370_09310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GT370_09370	COG0488	(ABC) transporter
GT370_09385	COG0436	Aminotransferase
GT370_09390	COG1764	response to oxidative stress
GT370_09400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT370_09415	COG1160	GTP binding
GT370_09425	COG0488	(ABC) transporter
GT370_09435	COG3842	ATPase activity
GT370_09440	COG3842	ATPase activity
GT370_09450	COG1177	transmembrane transport
GT370_09455	COG3284	Transcriptional regulator
GT370_09460	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GT370_09460	COG0517	IMP dehydrogenase activity
GT370_09460	COG0617	tRNA 3'-terminal CCA addition
GT370_09470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GT370_09500	COG1045	serine acetyltransferase
GT370_09510	COG4191	Histidine kinase
GT370_09510	COG0784	Response regulator, receiver
GT370_09515	COG0129	dihydroxy-acid dehydratase activity
GT370_09520	COG0583	DNA-binding transcription factor activity
GT370_09525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GT370_09535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GT370_09545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GT370_09550	COG0287	Prephenate dehydrogenase
GT370_09560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GT370_09590	COG2223	nitrite transmembrane transporter activity
GT370_09595	COG2261	transglycosylase associated protein
GT370_09620	COG1562	ergosterol biosynthetic process
GT370_09625	COG1562	ergosterol biosynthetic process
GT370_09645	COG1218	3'(2'),5'-bisphosphate nucleotidase
GT370_09655	COG0175	sulfate reduction
GT370_09660	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_09675	COG0436	Aminotransferase
GT370_09680	COG2086	electron transfer activity
GT370_09695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT370_09700	COG0251	oxidation-reduction process
GT370_09710	COG3971	2-oxopent-4-enoate hydratase activity
GT370_09715	COG3971	2-oxopent-4-enoate hydratase activity
GT370_09720	COG0179	Fumarylacetoacetate (FAA) hydrolase
GT370_09730	COG0477	Major facilitator Superfamily
GT370_09745	COG0583	DNA-binding transcription factor activity
GT370_09755	COG3842	ATPase activity
GT370_09760	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT370_09770	COG1177	transmembrane transport
GT370_09825	COG0583	DNA-binding transcription factor activity
GT370_09845	COG0583	DNA-binding transcription factor activity
GT370_09855	COG2203	Gaf domain
GT370_09855	COG5001	Diguanylate cyclase
GT370_09855	COG4251	negative regulation of phosphorylation
GT370_09855	COG3706	GGDEF domain
GT370_09865	COG0702	epimerase
GT370_09875	COG0300	oxidoreductase activity
GT370_09880	COG0300	oxidoreductase activity
GT370_09890	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_09930	COG0028	Belongs to the TPP enzyme family
GT370_09935	COG3335	DDE superfamily endonuclease
GT370_09955	COG3436	PFAM IS66 Orf2 family protein
GT370_10010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GT370_10045	COG5489	Protein of unknown function (DUF736)
GT370_10065	COG0582	viral genome integration into host DNA
GT370_10070	COG0582	viral genome integration into host DNA
GT370_10075	COG4974	Belongs to the 'phage' integrase family
GT370_10095	COG0789	Transcriptional regulator
GT370_10095	COG4978	Transcriptional regulator
GT370_10100	COG2814	Major facilitator Superfamily
GT370_10130	COG1476	TRANSCRIPTIONal
GT370_10135	COG2963	transposase activity
GT370_10140	COG3436	PFAM IS66 Orf2 family protein
GT370_10145	COG2433	Pfam Transposase IS66
GT370_10150	COG3318	Belongs to the UPF0149 family
GT370_10185	COG3008	intermembrane lipid transfer
GT370_10190	COG2995	paraquat-inducible protein a
GT370_10200	COG2199	diguanylate cyclase activity
GT370_10200	COG2203	Gaf domain
GT370_10200	COG2200	EAL domain
GT370_10205	COG5001	Diguanylate cyclase
GT370_10205	COG3300	MHYT domain
GT370_10225	COG2207	Transcriptional regulator
GT370_10235	COG3300	MHYT domain
GT370_10235	COG5001	Diguanylate cyclase
GT370_10265	COG3318	Belongs to the UPF0149 family
GT370_10270	COG2433	Pfam Transposase IS66
GT370_10275	COG3436	PFAM IS66 Orf2 family protein
GT370_10280	COG2963	transposase activity
GT370_10285	COG3300	MHYT domain
GT370_10285	COG5001	Diguanylate cyclase
GT370_10300	COG1476	TRANSCRIPTIONal
GT370_10320	COG2963	transposase activity
GT370_10325	COG3436	PFAM IS66 Orf2 family protein
GT370_10390	COG0583	DNA-binding transcription factor activity
GT370_10395	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_10400	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT370_10400	COG0596	Alpha beta hydrolase
GT370_10405	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_10415	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_10420	COG5489	Protein of unknown function (DUF736)
GT370_10435	COG4974	Belongs to the 'phage' integrase family
GT370_10440	COG0582	viral genome integration into host DNA
GT370_10445	COG4974	Belongs to the 'phage' integrase family
GT370_10480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GT370_10525	COG3318	Belongs to the UPF0149 family
GT370_10530	COG2433	Pfam Transposase IS66
GT370_10535	COG3436	PFAM IS66 Orf2 family protein
GT370_10540	COG2963	transposase activity
GT370_10560	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GT370_10680	COG0463	Glycosyl transferase, family 2
GT370_10690	COG2814	Major facilitator Superfamily
GT370_10715	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GT370_10735	COG0840	transmembrane signaling receptor activity
GT370_10745	COG0778	Nitroreductase
GT370_10775	COG1012	belongs to the aldehyde dehydrogenase family
GT370_10810	COG1522	sequence-specific DNA binding
GT370_10815	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GT370_10825	COG0366	Alpha amylase catalytic
GT370_10840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GT370_10855	COG1640	4-alpha-glucanotransferase
GT370_10860	COG1640	4-alpha-glucanotransferase
GT370_10885	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GT370_10895	COG2271	Major facilitator Superfamily
GT370_10900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GT370_10905	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GT370_10915	COG1393	Belongs to the ArsC family
GT370_10920	COG1879	ABC-type sugar transport system periplasmic component
GT370_10935	COG1609	Transcriptional regulator
GT370_10940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT370_10950	COG2186	Transcriptional regulator
GT370_10955	COG1027	Aspartate ammonia-lyase
GT370_10960	COG1113	amino acid transport
GT370_10965	COG0252	asparaginase activity
GT370_10975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GT370_10985	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT370_10995	COG0539	negative regulation of cytoplasmic translation
GT370_11025	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GT370_11030	COG4974	Belongs to the 'phage' integrase family
GT370_11040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GT370_11060	COG1696	Membrane protein involved in D-alanine export
GT370_11085	COG1116	anion transmembrane transporter activity
GT370_11090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT370_11100	COG0203	ribosomal protein L17
GT370_11105	COG0202	RNA polymerase activity
GT370_11110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GT370_11115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GT370_11120	COG0563	adenylate kinase activity
GT370_11130	COG0200	Binds to the 23S rRNA
GT370_11135	COG1841	ribosomal large subunit assembly
GT370_11140	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GT370_11145	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GT370_11155	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GT370_11160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GT370_11165	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GT370_11170	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GT370_11175	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GT370_11180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GT370_11185	COG0255	Belongs to the universal ribosomal protein uL29 family
GT370_11190	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GT370_11195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GT370_11200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GT370_11210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GT370_11215	COG0089	rRNA binding
GT370_11220	COG0088	Forms part of the polypeptide exit tunnel
GT370_11225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GT370_11235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GT370_11240	COG0049	tRNA binding
GT370_11245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GT370_11250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GT370_11255	COG0085	RNA polymerase activity
GT370_11265	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GT370_11270	COG0081	regulation of translation
GT370_11280	COG1335	isochorismatase
GT370_11285	COG1278	Cold shock
GT370_11300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GT370_11310	COG0315	cyclic pyranopterin monophosphate synthase activity
GT370_11315	COG0134	indole-3-glycerol-phosphate synthase activity
GT370_11345	COG0149	triose-phosphate isomerase activity
GT370_11350	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GT370_11375	COG4221	oxidoreductase activity
GT370_11400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GT370_11405	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GT370_11425	COG0305	Participates in initiation and elongation during chromosome replication
GT370_11430	COG0045	succinate-CoA ligase (ADP-forming) activity
GT370_11430	COG1042	CoA-binding domain protein
GT370_11430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GT370_11440	COG0360	Binds together with S18 to 16S ribosomal RNA
GT370_11445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GT370_11450	COG0359	binds to the 23S rRNA
GT370_11460	COG0616	signal peptide processing
GT370_11470	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GT370_11480	COG0628	permease
GT370_11485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GT370_11515	COG1862	Preprotein translocase
GT370_11525	COG0142	geranyltranstransferase activity
GT370_11565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GT370_11565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT370_11590	COG0477	Major facilitator Superfamily
GT370_11600	COG2835	tetraacyldisaccharide 4'-kinase activity
GT370_11640	COG0717	Belongs to the dCTP deaminase family
GT370_11655	COG2372	response to copper ion
GT370_11675	COG0196	riboflavin kinase activity
GT370_11690	COG2853	Lipoprotein
GT370_11705	COG2264	protein methyltransferase activity
GT370_11745	COG3750	Belongs to the UPF0335 family
GT370_11755	COG0469	pyruvate kinase activity
GT370_11780	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GT370_11795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GT370_11805	COG2885	chlorophyll binding
GT370_11805	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GT370_11815	COG2885	chlorophyll binding
GT370_11815	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GT370_11845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT370_11885	COG1136	(ABC) transporter
GT370_11895	COG0442	prolyl-tRNA aminoacylation
GT370_11915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GT370_11925	COG1007	ATP synthesis coupled electron transport
GT370_11940	COG0713	ATP synthesis coupled electron transport
GT370_11950	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT370_11955	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GT370_11970	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GT370_11975	COG0649	NAD binding
GT370_11980	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT370_11985	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT370_11990	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT370_12005	COG0776	regulation of translation
GT370_12015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GT370_12020	COG0740	serine-type endopeptidase activity
GT370_12025	COG0544	peptidyl-prolyl cis-trans isomerase activity
GT370_12035	COG2982	Protein involved in outer membrane biogenesis
GT370_12050	COG1254	Belongs to the acylphosphatase family
GT370_12055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT370_12085	COG0662	Cupin 2, conserved barrel domain protein
GT370_12085	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GT370_12090	COG2814	Major facilitator Superfamily
GT370_12100	COG0484	heat shock protein binding
GT370_12120	COG0346	lactoylglutathione lyase activity
GT370_12125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GT370_12140	COG1396	sequence-specific DNA binding
GT370_12140	COG3800	Transcriptional regulator
GT370_12150	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GT370_12155	COG0735	belongs to the Fur family
GT370_12170	COG1121	(ABC) transporter
GT370_12180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT370_12205	COG4191	Histidine kinase
GT370_12210	COG4566	intracellular signal transduction
GT370_12220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GT370_12225	COG0228	four-way junction DNA binding
GT370_12230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GT370_12240	COG0335	large ribosomal subunit rRNA binding
GT370_12245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT370_12250	COG0066	3-isopropylmalate dehydratase activity
GT370_12295	COG0582	viral genome integration into host DNA
GT370_12365	COG0583	DNA-binding transcription factor activity
GT370_12370	COG4221	oxidoreductase activity
GT370_12380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GT370_12380	COG3453	Protein conserved in bacteria
GT370_12500	COG3002	Belongs to the UPF0753 family
GT370_12510	COG3002	Belongs to the UPF0753 family
GT370_12540	COG1741	Belongs to the pirin family
GT370_12555	COG3284	Transcriptional regulator
GT370_12560	COG1063	alcohol dehydrogenase
GT370_12590	COG0028	Belongs to the TPP enzyme family
GT370_12600	COG3052	prosthetic group binding
GT370_12635	COG0477	Major facilitator Superfamily
GT370_12645	COG1053	succinate dehydrogenase
GT370_12645	COG3976	FMN-binding domain protein
GT370_12650	COG1802	Transcriptional regulator
GT370_12675	COG0784	Response regulator, receiver
GT370_12680	COG4251	negative regulation of phosphorylation
GT370_12730	COG1877	trehalose-phosphatase activity
GT370_12735	COG3038	cytochrome b561
GT370_12740	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GT370_12750	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GT370_12760	COG2205	protein histidine kinase activity
GT370_12805	COG0277	FAD linked oxidase domain protein
GT370_12810	COG0277	FAD linked oxidase domain protein
GT370_12830	COG1172	Belongs to the binding-protein-dependent transport system permease family
GT370_12840	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT370_12850	COG1454	alcohol dehydrogenase
GT370_12870	COG0784	Response regulator, receiver
GT370_12870	COG2205	protein histidine kinase activity
GT370_12870	COG5002	protein histidine kinase activity
GT370_12875	COG2205	protein histidine kinase activity
GT370_12875	COG3437	response regulator, receiver
GT370_12875	COG3850	Histidine kinase
GT370_12875	COG4999	Histidine kinase
GT370_12880	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GT370_12890	COG5002	protein histidine kinase activity
GT370_12890	COG0784	Response regulator, receiver
GT370_12900	COG2837	iron assimilation
GT370_12915	COG2186	Transcriptional regulator
GT370_12920	COG3258	Cytochrome c
GT370_12925	COG0154	amidase activity
GT370_12930	COG0154	amidase activity
GT370_12940	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GT370_12950	COG2814	Major facilitator Superfamily
GT370_12960	COG1309	transcriptional regulator
GT370_13005	COG1335	isochorismatase
GT370_13045	COG0142	geranyltranstransferase activity
GT370_13050	COG1722	exodeoxyribonuclease VII activity
GT370_13110	COG1196	nuclear chromosome segregation
GT370_13200	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GT370_13235	COG0109	protoheme IX farnesyltransferase activity
GT370_13255	COG2010	Cytochrome c
GT370_13255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GT370_13260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GT370_13260	COG1565	acr, cog1565
GT370_13265	COG3754	Rhamnan synthesis protein F
GT370_13285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GT370_13290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GT370_13300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GT370_13365	COG5425	PFAM Usg family protein
GT370_13375	COG0459	protein refolding
GT370_13390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GT370_13410	COG0251	oxidation-reduction process
GT370_13455	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GT370_13455	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GT370_13480	COG2204	response regulator
GT370_13485	COG5002	protein histidine kinase activity
GT370_13490	COG0745	RESPONSE REGULATOR receiver
GT370_13535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GT370_13560	COG0768	penicillin binding
GT370_13570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GT370_13600	COG0248	Ppx GppA phosphatase
GT370_13620	COG0778	Nitroreductase
GT370_13625	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GT370_13660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GT370_13695	COG0531	amino acid
GT370_13705	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT370_13750	COG4786	Flagellar basal body rod
GT370_13750	COG1256	bacterial-type flagellum assembly
GT370_13755	COG1705	Flagellar rod assembly protein muramidase FlgJ
GT370_13755	COG3951	Flagellar rod assembly protein muramidase FlgJ
GT370_13760	COG1706	bacterial-type flagellum-dependent cell motility
GT370_13770	COG4786	Flagellar basal body rod
GT370_13775	COG4787	bacterial-type flagellum-dependent cell motility
GT370_13780	COG1749	Flagellar hook protein flgE
GT370_13785	COG4786	Flagellar basal body rod
GT370_13800	COG1815	bacterial-type flagellum-dependent cell motility
GT370_13810	COG0745	RESPONSE REGULATOR receiver
GT370_13815	COG1677	Flagellar hook-basal body complex protein FliE
GT370_13830	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GT370_13850	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT370_13855	COG1191	sigma factor activity
GT370_13860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GT370_13865	COG1360	Flagellar Motor Protein
GT370_13940	COG0254	rRNA binding
GT370_13955	COG1346	cytolysis
GT370_13975	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_13980	COG3546	catalase activity
GT370_13985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT370_13990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT370_14010	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT370_14025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GT370_14060	COG2982	Protein involved in outer membrane biogenesis
GT370_14065	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GT370_14085	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GT370_14130	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GT370_14135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT370_14150	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GT370_14155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT370_14160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT370_14165	COG1238	metal cluster binding
GT370_14170	COG1349	DNA-binding transcription factor activity
GT370_14200	COG0105	UTP biosynthetic process
GT370_14205	COG0488	(ABC) transporter
GT370_14215	COG0628	permease
GT370_14225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT370_14230	COG0765	amino acid transport
GT370_14300	COG0515	serine threonine protein kinase
GT370_14300	COG2815	serine threonine protein kinase
GT370_14320	COG2885	chlorophyll binding
GT370_14395	COG0631	protein serine/threonine phosphatase activity
GT370_14460	COG2945	thiolester hydrolase activity
GT370_14460	COG0596	Alpha beta hydrolase
GT370_14465	COG0583	DNA-binding transcription factor activity
GT370_14470	COG0667	Aldo Keto reductase
GT370_14480	COG2207	Transcriptional regulator
GT370_14515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GT370_14520	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GT370_14530	COG1872	DUF167
GT370_14535	COG0583	DNA-binding transcription factor activity
GT370_14540	COG0492	ferredoxin-NADP+ reductase activity
GT370_14550	COG0251	oxidation-reduction process
GT370_14560	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GT370_14570	COG0745	RESPONSE REGULATOR receiver
GT370_14580	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GT370_14585	COG3179	chitinase
GT370_14600	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GT370_14630	COG0842	Transport permease protein
GT370_14635	COG1131	(ABC) transporter
GT370_14655	COG2031	fatty acid transporter
GT370_14660	COG3842	ATPase activity
GT370_14670	COG0395	ABC-type sugar transport system, permease component
GT370_14680	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_14690	COG3684	Belongs to the aldolase LacD family
GT370_14705	COG2186	Transcriptional regulator
GT370_14745	COG0511	ligase activity, forming carbon-carbon bonds
GT370_14745	COG5016	pyruvate
GT370_14765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT370_14810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GT370_14820	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GT370_14820	COG1082	Xylose isomerase domain protein TIM barrel
GT370_14830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GT370_14840	COG2271	Major facilitator Superfamily
GT370_14870	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT370_14895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GT370_14910	COG1053	succinate dehydrogenase
GT370_14930	COG1414	Transcriptional regulator
GT370_14935	COG1414	Transcriptional regulator
GT370_14955	COG0583	DNA-binding transcription factor activity
GT370_14960	COG2267	carboxylic ester hydrolase activity
GT370_14965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GT370_14970	COG3485	protocatechuate 3,4-dioxygenase
GT370_14975	COG3485	protocatechuate 3,4-dioxygenase
GT370_15010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GT370_15015	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GT370_15035	COG0587	DNA-directed DNA polymerase activity
GT370_15040	COG1476	TRANSCRIPTIONal
GT370_15065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT370_15070	COG0477	Major facilitator Superfamily
GT370_15080	COG2814	Major facilitator Superfamily
GT370_15095	COG3328	transposase activity
GT370_15125	COG2963	transposase activity
GT370_15130	COG3436	PFAM IS66 Orf2 family protein
GT370_15135	COG2433	Pfam Transposase IS66
GT370_15140	COG3318	Belongs to the UPF0149 family
GT370_15185	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GT370_15215	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GT370_15245	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GT370_15250	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GT370_15450	COG0438	transferase activity, transferring glycosyl groups
GT370_15450	COG1216	Glycosyl transferase, family 2
GT370_15475	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GT370_15490	COG0617	tRNA 3'-terminal CCA addition
GT370_15510	COG0357	Ribosomal RNA small subunit methyltransferase G
GT370_15525	COG0840	transmembrane signaling receptor activity
GT370_15540	COG0495	leucyl-tRNA aminoacylation
GT370_15550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GT370_15565	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GT370_15570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT370_15575	COG1981	membrane
GT370_15580	COG0300	oxidoreductase activity
GT370_15585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GT370_15595	COG3243	poly(R)-hydroxyalkanoic acid synthase
GT370_15625	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_15635	COG0517	IMP dehydrogenase activity
GT370_15640	COG1132	(ABC) transporter
GT370_15650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GT370_15650	COG1918	ferrous iron import across plasma membrane
GT370_15660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GT370_15670	COG0193	aminoacyl-tRNA hydrolase activity
GT370_15675	COG0012	GTP binding
GT370_15695	COG1278	Cold shock
GT370_15700	COG3239	Fatty acid desaturase
GT370_15710	COG1982	Orn Lys Arg decarboxylase major
GT370_15725	COG1294	oxidase, subunit
GT370_15730	COG1271	oxidase subunit
GT370_15735	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GT370_15740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GT370_15745	COG1132	(ABC) transporter
GT370_15750	COG4988	ABC transporter
GT370_15760	COG2351	hydroxyisourate hydrolase activity
GT370_15770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT370_15795	COG1620	l-lactate permease
GT370_15830	COG1116	anion transmembrane transporter activity
GT370_15835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT370_15865	COG1132	(ABC) transporter
GT370_15870	COG4988	ABC transporter
GT370_15875	COG4988	ABC transporter
GT370_15885	COG1271	oxidase subunit
GT370_15910	COG0784	Response regulator, receiver
GT370_15910	COG2198	Histidine kinase
GT370_15910	COG5002	protein histidine kinase activity
GT370_15965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GT370_15970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GT370_15985	COG1012	belongs to the aldehyde dehydrogenase family
GT370_16015	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GT370_16020	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
GT370_16025	COG0535	radical SAM domain protein
GT370_16030	COG0535	radical SAM domain protein
GT370_16060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GT370_16075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GT370_16090	COG0612	Peptidase, M16
GT370_16095	COG0312	modulator of DNA gyrase
GT370_16105	COG1970	mechanosensitive ion channel activity
GT370_16125	COG0752	glycyl-tRNA synthetase alpha subunit
GT370_16145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GT370_16160	COG0668	transmembrane transport
GT370_16210	COG0174	glutamine synthetase
GT370_16250	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GT370_16265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GT370_16270	COG0322	excinuclease ABC activity
GT370_16280	COG0745	RESPONSE REGULATOR receiver
GT370_16320	COG0590	tRNA wobble adenosine to inosine editing
GT370_16330	COG1612	heme a metabolic process
GT370_16340	COG0440	acetolactate synthase activity
GT370_16345	COG0028	Belongs to the TPP enzyme family
GT370_16350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GT370_16355	COG0560	Phosphoserine phosphatase
GT370_16355	COG3830	Belongs to the UPF0237 family
GT370_16380	COG0424	maF-like protein
GT370_16415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GT370_16430	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GT370_16460	COG0354	folic acid binding
GT370_16465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT370_16480	COG2814	Major facilitator Superfamily
GT370_16500	COG0235	Class ii aldolase
GT370_16505	COG1278	Cold shock
GT370_16515	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GT370_16540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GT370_16555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GT370_16565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GT370_16570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GT370_16580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GT370_16590	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
GT370_16655	COG5001	Diguanylate cyclase
GT370_16655	COG3300	MHYT domain
GT370_16660	COG5001	Diguanylate cyclase
GT370_16660	COG3300	MHYT domain
GT370_16670	COG0180	Tryptophanyl-tRNA synthetase
GT370_16695	COG0745	RESPONSE REGULATOR receiver
GT370_16700	COG1846	Transcriptional regulator
GT370_16730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GT370_16730	COG0678	peroxiredoxin activity
GT370_16750	COG0347	Belongs to the P(II) protein family
GT370_16765	COG0746	molybdenum cofactor guanylyltransferase activity
GT370_16785	COG0456	acetyltransferase
GT370_16835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GT370_16845	COG3813	Protein conserved in bacteria
GT370_16860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GT370_16875	COG0438	transferase activity, transferring glycosyl groups
GT370_16885	COG4953	penicillin-binding protein 1C
GT370_16910	COG0657	acetylesterase activity
GT370_16910	COG2755	lipolytic protein G-D-S-L family
GT370_16945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GT370_16960	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GT370_16995	COG1253	flavin adenine dinucleotide binding
GT370_17000	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GT370_17005	COG1702	phosphate starvation-inducible protein PhoH
GT370_17010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GT370_17025	COG0670	Belongs to the BI1 family
GT370_17050	COG3474	cytochrome
GT370_17070	COG0328	RNA-DNA hybrid ribonuclease activity
GT370_17085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT370_17095	COG0439	Biotin carboxylase
GT370_17115	COG2022	thiamine diphosphate biosynthetic process
GT370_17130	COG0237	dephospho-CoA kinase activity
GT370_17135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GT370_17145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GT370_17165	COG3454	Phosphonate metabolism
GT370_17170	COG3454	Phosphonate metabolism
GT370_17175	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GT370_17180	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GT370_17215	COG3243	poly(R)-hydroxyalkanoic acid synthase
GT370_17230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GT370_17250	COG0742	ribosomal rna small subunit methyltransferase
GT370_17255	COG1187	pseudouridine synthase activity
GT370_17260	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GT370_17270	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GT370_17300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GT370_17305	COG0314	molybdopterin synthase activity
GT370_17315	COG1763	Mo-molybdopterin cofactor biosynthetic process
GT370_17320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GT370_17325	COG0725	ABC transporter, periplasmic molybdate-binding protein
GT370_17340	COG3842	ATPase activity
GT370_17350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GT370_17355	COG0045	succinate-CoA ligase (ADP-forming) activity
GT370_17360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GT370_17370	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT370_17385	COG1597	lipid kinase activity
GT370_17395	COG0039	L-malate dehydrogenase activity
GT370_17400	COG0651	ATP synthesis coupled electron transport
GT370_17445	COG0649	NAD binding
GT370_17450	COG0649	NAD binding
GT370_17465	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GT370_17480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GT370_17485	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GT370_17490	COG0343	queuine tRNA-ribosyltransferase activity
GT370_17495	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GT370_17525	COG0425	Belongs to the sulfur carrier protein TusA family
GT370_17530	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GT370_17535	COG0242	peptide deformylase activity
GT370_17560	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GT370_17565	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GT370_17580	COG0779	Required for maturation of 30S ribosomal subunits
GT370_17585	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GT370_17620	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_17625	COG0477	Major facilitator Superfamily
GT370_17645	COG4977	sequence-specific DNA binding
GT370_17655	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_17670	COG0243	molybdopterin cofactor binding
GT370_17690	COG3008	intermembrane lipid transfer
GT370_17715	COG2188	Transcriptional regulator
GT370_17720	COG2814	Major facilitator Superfamily
GT370_17745	COG3220	belongs to the UPF0276 family
GT370_17755	COG1595	DNA-templated transcription, initiation
GT370_17765	COG0653	protein targeting
GT370_17770	COG3781	membrane
GT370_17775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT370_17780	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GT370_17785	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GT370_17790	COG1999	signal sequence binding
GT370_17825	COG1566	PFAM secretion protein HlyD family protein
GT370_17865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GT370_17865	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT370_17870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GT370_17875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT370_17885	COG1660	Displays ATPase and GTPase activities
GT370_17900	COG0745	RESPONSE REGULATOR receiver
GT370_17920	COG2223	nitrite transmembrane transporter activity
GT370_17935	COG0542	response to heat
GT370_17940	COG1335	isochorismatase
GT370_17995	COG4974	Belongs to the 'phage' integrase family
GT370_18010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT370_18025	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_18080	COG4974	Belongs to the 'phage' integrase family
GT370_18085	COG0582	viral genome integration into host DNA
GT370_18090	COG4974	Belongs to the 'phage' integrase family
GT370_18115	COG5489	Protein of unknown function (DUF736)
GT370_18120	COG0210	DNA helicase
GT370_18175	COG3318	Belongs to the UPF0149 family
GT370_18180	COG2433	Pfam Transposase IS66
GT370_18185	COG3436	PFAM IS66 Orf2 family protein
GT370_18190	COG2963	transposase activity
GT370_18215	COG0142	geranyltranstransferase activity
GT370_18255	COG3093	addiction module antidote protein HigA
GT370_18310	COG1024	Enoyl-CoA hydratase
GT370_18315	COG0824	Thioesterase
GT370_18325	COG2249	NAD(P)H dehydrogenase (quinone) activity
GT370_18340	COG1414	Transcriptional regulator
GT370_18345	COG3836	Belongs to the HpcH HpaI aldolase family
GT370_18350	COG2814	Major facilitator Superfamily
GT370_18360	COG3246	L-lysine catabolic process to acetate
GT370_18410	COG5002	protein histidine kinase activity
GT370_18425	COG2205	protein histidine kinase activity
GT370_18430	COG0811	peptide transport
GT370_18435	COG0848	biopolymer transport protein
GT370_18485	COG5642	Protein of unknown function (DUF2384)
GT370_18545	COG1414	Transcriptional regulator
GT370_18565	COG1609	Transcriptional regulator
GT370_18600	COG3254	rhamnose metabolic process
GT370_18615	COG1129	ABC transporter
GT370_18630	COG3347	Dehydrogenase
GT370_18630	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_18640	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_18640	COG3347	Dehydrogenase
GT370_18645	COG4952	isomerase
GT370_18665	COG0583	DNA-binding transcription factor activity
GT370_18670	COG0477	Major facilitator Superfamily
GT370_18675	COG1024	Enoyl-CoA hydratase
GT370_18685	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT370_18690	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT370_18725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT370_18730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT370_18735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT370_18810	COG1278	Cold shock
GT370_18870	COG0642	Histidine kinase
GT370_18905	COG0672	)-iron permease
GT370_18925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT370_18935	COG0277	FAD linked oxidase domain protein
GT370_18935	COG0247	lactate metabolic process
GT370_18940	COG0247	lactate metabolic process
GT370_18940	COG0277	FAD linked oxidase domain protein
GT370_18950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT370_18960	COG1802	Transcriptional regulator
GT370_18965	COG2271	Major facilitator Superfamily
GT370_18980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT370_18985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT370_18995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT370_19005	COG1228	amidohydrolase
GT370_19040	COG5001	Diguanylate cyclase
GT370_19040	COG5002	protein histidine kinase activity
GT370_19040	COG3447	MASE1 domain protein
GT370_19055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT370_19060	COG0154	amidase activity
GT370_19065	COG0154	amidase activity
GT370_19075	COG3842	ATPase activity
GT370_19080	COG0395	ABC-type sugar transport system, permease component
GT370_19090	COG1653	transport
GT370_19105	COG0800	Aldolase
GT370_19115	COG3265	gluconokinase activity
GT370_19120	COG2271	Major facilitator Superfamily
GT370_19125	COG2271	Major facilitator Superfamily
GT370_19130	COG1609	Transcriptional regulator
GT370_19135	COG1609	Transcriptional regulator
GT370_19150	COG1741	Belongs to the pirin family
GT370_19155	COG0583	DNA-binding transcription factor activity
GT370_19160	COG1802	Transcriptional regulator
GT370_19165	COG1914	H( )-stimulated, divalent metal cation uptake system
GT370_19170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GT370_19180	COG4336	lyase activity
GT370_19190	COG4770	biotin carboxylase activity
GT370_19200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT370_19210	COG1595	DNA-templated transcription, initiation
GT370_19225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT370_19240	COG3300	MHYT domain
GT370_19240	COG5001	Diguanylate cyclase
GT370_19245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT370_19250	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_19305	COG0811	peptide transport
GT370_19330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT370_19345	COG1132	(ABC) transporter
GT370_19380	COG0531	amino acid
GT370_19415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT370_19430	COG1737	Transcriptional regulator
GT370_19435	COG1116	anion transmembrane transporter activity
GT370_19440	COG0390	transport system, permease component
GT370_19450	COG0811	peptide transport
GT370_19455	COG0848	biopolymer transport protein
GT370_19480	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GT370_19495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GT370_19505	COG0154	amidase activity
GT370_19525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT370_19530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT370_19535	COG1349	DNA-binding transcription factor activity
GT370_19540	COG0154	amidase activity
GT370_19625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT370_19625	COG1116	anion transmembrane transporter activity
GT370_19635	COG2223	nitrite transmembrane transporter activity
GT370_19640	COG2223	nitrite transmembrane transporter activity
GT370_19645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GT370_19655	COG1648	precorrin-2 dehydrogenase activity
GT370_19655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GT370_19660	COG0243	molybdopterin cofactor binding
GT370_19670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT370_19690	COG2205	protein histidine kinase activity
GT370_19690	COG0784	Response regulator, receiver
GT370_19690	COG2198	Histidine kinase
GT370_19735	COG1573	uracil-dna glycosylase
GT370_19745	COG0583	DNA-binding transcription factor activity
GT370_19750	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_19755	COG3959	Transketolase, thiamine diphosphate binding domain
GT370_19760	COG3959	Transketolase, thiamine diphosphate binding domain
GT370_19765	COG3958	Transketolase
GT370_19770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT370_19780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GT370_19785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT370_19810	COG3511	phospholipase C
GT370_19815	COG1858	cytochrome C peroxidase
GT370_19830	COG0318	PFAM AMP-dependent synthetase and ligase
GT370_19840	COG1414	Transcriptional regulator
GT370_19845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT370_19860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GT370_19865	COG1028	Short-chain dehydrogenase reductase Sdr
GT370_19870	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GT370_19905	COG1501	Belongs to the glycosyl hydrolase 31 family
GT370_19940	COG1609	Transcriptional regulator
GT370_19950	COG0028	Belongs to the TPP enzyme family
GT370_19960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT370_19975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT370_19980	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GT370_19990	COG0243	molybdopterin cofactor binding
GT370_19995	COG0243	molybdopterin cofactor binding
GT370_20060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT370_20070	COG2271	Major facilitator Superfamily
GT370_20080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT370_20095	COG2186	Transcriptional regulator
GT370_20110	COG3395	kinase activity
GT370_20115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GT370_20120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GT370_20135	COG1764	response to oxidative stress
GT370_20140	COG0678	peroxiredoxin activity
GT370_20210	COG1157	protein secretion by the type III secretion system
GT370_20225	COG1360	Flagellar Motor Protein
GT370_20230	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GT370_20235	COG1191	sigma factor activity
GT370_20270	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GT370_20290	COG1815	bacterial-type flagellum-dependent cell motility
GT370_20320	COG4786	Flagellar basal body rod
GT370_20325	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GT370_20330	COG1706	bacterial-type flagellum-dependent cell motility
GT370_20340	COG3951	Flagellar rod assembly protein muramidase FlgJ
GT370_20340	COG1705	Flagellar rod assembly protein muramidase FlgJ
GT370_20365	COG1987	bacterial-type flagellum assembly
GT370_20395	COG3387	PFAM Glycoside hydrolase 15-related
GT370_20415	COG3386	PFAM SMP-30 Gluconolaconase
GT370_20425	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GT370_20475	COG0356	it plays a direct role in the translocation of protons across the membrane
GT370_20480	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GT370_20485	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GT370_20505	COG2875	Belongs to the precorrin methyltransferase family
GT370_20520	COG2099	Precorrin-6x reductase
GT370_20565	COG1492	cobalamin metabolic process
GT370_20575	COG0778	Nitroreductase
GT370_20585	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GT370_20600	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GT370_20605	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate