locus-tag	class	description
Acel_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Acel_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Acel_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Acel_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Acel_0005	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Acel_0006	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Acel_0013	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
Acel_0016	ENOG4108U4N	(sortase) family
Acel_0019	ENOG4105D9P	serine threonine protein kinase
Acel_0020	ENOG4105CJN	penicillin-binding protein
Acel_0023	ENOG4105HZM	Fha domain containing protein
Acel_0024	ENOG4105TV9	FHA Domain-Containing protein
Acel_0031	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
Acel_0032	ENOG4105CPP	Dehydrogenase, E1 component
Acel_0035	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Acel_0045	ENOG4105DXB	Major Facilitator superfamily
Acel_0047	ENOG4105KJF	protein tyrosine phosphatase
Acel_0048	ENOG4105CXK	mandelate racemase muconate lactonizing
Acel_0049	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
Acel_0052	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Acel_0053	ENOG4105D7N	magnesium and cobalt transport protein CorA
Acel_0056	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Acel_0059	ENOG4105KHC	sulfurtransferase
Acel_0060	ENOG4105PKJ	carbohydrate binding
Acel_0063	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Acel_0069	ENOG4107SET	aldo keto reductase
Acel_0071	ENOG4108UVJ	appr-1-p processing domain protein
Acel_0072	ENOG4105E2D	ec 3.2.1.52
Acel_0073	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Acel_0075	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Acel_0079	ENOG4105CTP	PilT protein domain protein
Acel_0080	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Acel_0081	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Acel_0082	ENOG4105C8N	cysteinyl-tRNA synthetase
Acel_0083	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Acel_0084	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
Acel_0088	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Acel_0096	ENOG4105BZU	Histidine kinase
Acel_0101	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Acel_0103	ENOG4106N3A	copper homeostasis protein cutc
Acel_0104	ENOG4105VEQ	Cold shock protein
Acel_0105	ENOG4105E63	Pfam:DUF178
Acel_0106	ENOG4108UIH	futalosine nucleosidase
Acel_0107	ENOG4108N0W	Major Facilitator superfamily
Acel_0112	ENOG4105CPC	Aldo Keto reductase
Acel_0114	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Acel_0116	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
Acel_0118	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Acel_0127	ENOG4108NVR	Methyl-accepting chemotaxis
Acel_0128	ENOG4105D17	glycoside hydrolase, family 3 domain protein
Acel_0132	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
Acel_0133	ENOG4105CS2	ec 3.2.1.21
Acel_0134	ENOG4105ETE	Transcriptional regulator (LacI family
Acel_0135	ENOG4108W9Q	Endoglucanase (EC 3.2.1.4)
Acel_0140	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Acel_0147	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Acel_0148	ENOG4105CPC	Aldo Keto reductase
Acel_0151	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
Acel_0153	ENOG4105CJ1	ABC, transporter
Acel_0156	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Acel_0158	ENOG4107USC	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
Acel_0159	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Acel_0163	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
Acel_0164	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
Acel_0165	ENOG4105BZU	Histidine kinase
Acel_0166	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Acel_0168	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Acel_0169	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Acel_0175	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Acel_0176	ENOG4105F8V	Hydrolase, tatD family
Acel_0178	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Acel_0179	ENOG4107S46	esterase, PHB depolymerase
Acel_0181	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Acel_0188	ENOG4105EKT	)-iron permease
Acel_0189	ENOG410650H	(LipO)protein
Acel_0190	ENOG4105DBE	peroxidase
Acel_0192	ENOG4108M15	ABC transporter
Acel_0194	ENOG4105BZU	Histidine kinase
Acel_0197	ENOG4108IAB	Phoh family
Acel_0198	ENOG4105ZXU	NLP P60 protein
Acel_0199	ENOG4105F0N	pyrophosphate phospho-hydrolase
Acel_0202	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Acel_0203	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Acel_0204	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Acel_0205	ENOG4105EUJ	GTP cyclohydrolase i
Acel_0206	ENOG4105CRK	lysyL-tRNA synthetase
Acel_0208	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Acel_0211	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Acel_0212	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Acel_0213	ENOG4108IYU	L-aspartate oxidase
Acel_0215	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Acel_0220	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Acel_0222	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Acel_0223	ENOG4105BZU	Histidine kinase
Acel_0226	ENOG4108JWX	
Acel_0229	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
Acel_0231	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Acel_0235	ENOG4105D52	delta-aminolevulinic acid dehydratase
Acel_0236	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Acel_0237	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Acel_0238	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Acel_0239	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
Acel_0245	ENOG4108XFF	
Acel_0246	ENOG4105DGU	Histone deacetylase
Acel_0249	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
Acel_0250	ENOG4108RH7	phosphoglycerate mutase
Acel_0251	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Acel_0252	ENOG4107QIV	Cytochrome c biogenesis protein
Acel_0254	ENOG4105CRE	cytochrome C
Acel_0255	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Acel_0257	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Acel_0259	ENOG4105DVY	radical SAM domain protein
Acel_0261	ENOG4105EV6	Pfam:DUF178
Acel_0263	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Acel_0264	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Acel_0265	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Acel_0266	ENOG4105P52	geranylgeranyl reductase
Acel_0268	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acel_0269	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Acel_0270	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acel_0273	ENOG4108IEH	NADH dehydrogenase subunit g
Acel_0274	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Acel_0275	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acel_0276	ENOG4105DF2	NADH dehydrogenase subunit j
Acel_0277	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acel_0280	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acel_0283	ENOG4105DQU	oxidoreductase, subunit beta
Acel_0284	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Acel_0286	ENOG4108VPT	UPF0234 protein
Acel_0287	ENOG4105WDJ	50S ribosomal protein L33
Acel_0288	ENOG410900P	UPF0336 protein
Acel_0291	ENOG4107R4N	Cell wall formation (By similarity)
Acel_0293	ENOG410683Z	Preprotein translocase SecE subunit
Acel_0295	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Acel_0296	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Acel_0297	ENOG4108VZM	50s ribosomal protein L10
Acel_0298	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Acel_0299	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Acel_0300	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Acel_0301	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Acel_0302	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Acel_0303	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Acel_0304	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Acel_0305	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Acel_0306	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Acel_0307	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Acel_0308	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Acel_0309	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Acel_0310	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Acel_0311	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Acel_0312	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Acel_0313	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Acel_0314	ENOG41082SA	50s ribosomal protein l29
Acel_0315	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Acel_0316	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Acel_0317	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Acel_0318	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Acel_0319	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Acel_0320	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Acel_0321	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Acel_0322	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Acel_0323	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Acel_0324	ENOG410849U	50S ribosomal protein L30
Acel_0325	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Acel_0327	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Acel_0329	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Acel_0330	ENOG41067V7	50S ribosomal protein L36
Acel_0331	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Acel_0332	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Acel_0333	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Acel_0334	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Acel_0335	ENOG4108ZT0	50S ribosomal protein l17
Acel_0336	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Acel_0341	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Acel_0342	ENOG4108UJD	30S ribosomal protein S9
Acel_0343	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Acel_0344	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Acel_0346	ENOG4105K56	Transcriptional regulator
Acel_0347	ENOG4105EYF	MMPL domain protein
Acel_0350	ENOG4105K6V	RNA polymerase
Acel_0352	ENOG4105CNN	ABC, transporter
Acel_0353	ENOG4105C2J	ABC transporter
Acel_0355	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Acel_0356	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Acel_0357	ENOG4108097	ATP-binding protein
Acel_0359	ENOG4108Z7F	N-acetyltransferase
Acel_0360	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Acel_0362	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Acel_0363	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Acel_0365	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Acel_0367	ENOG4107QVP	Dehydrogenase
Acel_0368	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Acel_0370	ENOG4106D2I	Chorismate mutase
Acel_0371	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Acel_0374	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
Acel_0376	ENOG4108K5P	(LipO)protein
Acel_0377	ENOG4105D5P	Methylmalonyl-coA mutase
Acel_0380	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Acel_0384	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Acel_0385	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Acel_0390	ENOG4105C31	Tryptophanyl-tRNA synthetase
Acel_0392	ENOG4105VEQ	Cold shock protein
Acel_0393	ENOG4105DZ1	carboxypeptidase
Acel_0395	ENOG4105D9P	serine threonine protein kinase
Acel_0397	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Acel_0400	ENOG4105E39	Enoyl-CoA hydratase
Acel_0401	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Acel_0403	ENOG4107QX3	carboxylase
Acel_0405	ENOG4105C1G	acyl-Coa dehydrogenase
Acel_0407	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Acel_0408	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Acel_0410	ENOG4108S4H	thioesterase Superfamily protein
Acel_0411	ENOG4108KGH	TRANSCRIPTIONal
Acel_0412	ENOG4107TB5	TRANSCRIPTIONal
Acel_0413	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
Acel_0416	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Acel_0419	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Acel_0421	ENOG4105EY8	ABC transporter
Acel_0422	ENOG4107RGC	Glycosyl transferase, family 2
Acel_0424	ENOG4105VRS	hydrolase family 18
Acel_0427	ENOG4105CGN	Glycosyl transferase (Group 1
Acel_0428	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Acel_0429	ENOG4105CPQ	Dehydrogenase
Acel_0430	ENOG4107HP6	Transcriptional regulator
Acel_0435	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
Acel_0436	ENOG4105DRS	transport system, permease
Acel_0437	ENOG4105C26	Dehydrogenase
Acel_0438	ENOG4105CKK	Glycosyl transferase, family 2
Acel_0447	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Acel_0448	ENOG4107T8Q	Glycosyl transferase (Group 1
Acel_0449	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
Acel_0450	ENOG4105C30	Nad-dependent epimerase dehydratase
Acel_0453	ENOG4105CIK	Amidinotransferase
Acel_0454	ENOG4105C8Y	Acetylornithine aminotransferase
Acel_0457	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
Acel_0460	ENOG4107RGC	Glycosyl transferase, family 2
Acel_0465	ENOG4107QKV	phosphomannomutase
Acel_0466	ENOG4105W49	UPF0434 protein
Acel_0468	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Acel_0469	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Acel_0475	ENOG41063PX	domain protein
Acel_0476	ENOG4107SET	aldo keto reductase
Acel_0478	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Acel_0479	ENOG4107QRS	glycosyltransferase group 2 family protein
Acel_0483	ENOG4108RWP	Major Facilitator Superfamily protein
Acel_0485	ENOG4105PP6	Membrane
Acel_0486	ENOG41063C6	UPF0235 protein
Acel_0489	ENOG41088CC	tellurite resistance protein tehB
Acel_0490	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Acel_0503	ENOG4105CEI	nitrite reductase
Acel_0507	ENOG4105R3A	Nitrate reductase
Acel_0508	ENOG4108IUE	nitrate reductase beta subunit
Acel_0519	ENOG4108YV4	Universal stress protein
Acel_0520	ENOG4105CD5	CoA-binding domain protein
Acel_0521	ENOG4107QRI	Phosphoketolase
Acel_0522	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Acel_0524	ENOG4107XUC	SirA family
Acel_0529	ENOG4105BZU	Histidine kinase
Acel_0530	ENOG4108YYC	ycei family
Acel_0533	ENOG4107TK4	histidinol-phosphate phosphatase
Acel_0534	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Acel_0535	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Acel_0536	ENOG4108RAV	Conserved protein
Acel_0537	ENOG4105SCY	DNAK suppressor
Acel_0538	ENOG4105EMN	RNA polymerase sigma factor
Acel_0542	ENOG41080RH	Thioredoxin
Acel_0543	ENOG4105VPX	protein, conserved in bacteria
Acel_0546	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Acel_0548	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Acel_0549	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
Acel_0550	ENOG4105CZX	twitching motility protein
Acel_0551	ENOG4105FDP	GntR family transcriptional regulator
Acel_0554	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Acel_0555	ENOG4105RD7	BadF BadG BcrA BcrD
Acel_0556	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Acel_0557	ENOG4105CE4	GlcNAc 6-P deacetylase
Acel_0558	ENOG4108IJ9	(ABC) transporter
Acel_0562	ENOG4108SU4	UPF0309 protein
Acel_0566	ENOG4108VEQ	Superoxide dismutase
Acel_0568	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Acel_0571	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
Acel_0572	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Acel_0573	ENOG4105DKQ	ROK family
Acel_0574	ENOG4105FDP	GntR family transcriptional regulator
Acel_0575	ENOG4105E2R	ROK family
Acel_0576	ENOG4108SU4	UPF0309 protein
Acel_0577	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Acel_0578	ENOG4105C2J	ABC transporter
Acel_0579	ENOG4105CNN	ABC, transporter
Acel_0580	ENOG4105CNN	ABC, transporter
Acel_0582	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
Acel_0583	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Acel_0586	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Acel_0587	ENOG4108UZE	carboxy-peptidase
Acel_0590	ENOG4108JYK	Dehydrogenase
Acel_0592	ENOG4105E7W	lamb ycsf family protein
Acel_0593	ENOG4105P4J	Allophanate hydrolase, subunit 1
Acel_0595	ENOG4105CJW	magnesium transporter
Acel_0596	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Acel_0597	ENOG4108JJ9	ABC, transporter
Acel_0598	ENOG4108JJ9	ABC, transporter
Acel_0599	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Acel_0600	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Acel_0601	ENOG410630M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
Acel_0604	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
Acel_0606	ENOG410834F	Transcriptional regulator
Acel_0607	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Acel_0614	ENOG4106R7G	Glycoside hydrolase family 5
Acel_0615	ENOG41065HY	1,4-beta-cellobiosidase
Acel_0615	ENOG41065HY	1,4-beta-cellobiosidase
Acel_0617	ENOG4105CYP	glycoside hydrolase, family
Acel_0619	ENOG4106R7G	Glycoside hydrolase family 5
Acel_0620	ENOG4105BZU	Histidine kinase
Acel_0623	ENOG4105K78	MarR family Transcriptional regulator
Acel_0624	ENOG4108RVA	ribokinase
Acel_0626	ENOG4105CHU	acetyl-coa acetyltransferase
Acel_0627	ENOG4108PYU	two-component system response regulator
Acel_0628	ENOG4105C75	arginyL-tRNA synthetase
Acel_0629	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Acel_0630	ENOG4105D6E	homoserine dehydrogenase
Acel_0631	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
Acel_0632	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Acel_0634	ENOG4107W19	lmbE family
Acel_0635	ENOG4107R8N	Glycosyl transferase, family 2
Acel_0637	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Acel_0638	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Acel_0639	ENOG4105PAD	Hydrolase
Acel_0640	ENOG4105VFB	Binds the 23S rRNA (By similarity)
Acel_0641	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Acel_0642	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Acel_0647	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
Acel_0649	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Acel_0650	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Acel_0651	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Acel_0652	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Acel_0653	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Acel_0654	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Acel_0657	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Acel_0658	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Acel_0659	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Acel_0661	ENOG4105F8C	transglutaminase domain-containing protein
Acel_0664	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
Acel_0665	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Acel_0667	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Acel_0672	ENOG4105CHU	acetyl-coa acetyltransferase
Acel_0675	ENOG4105K63	Thioredoxin
Acel_0676	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Acel_0677	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
Acel_0678	ENOG4105CG3	alpha amylase, catalytic region
Acel_0679	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
Acel_0680	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
Acel_0685	ENOG4105C10	Electron transfer flavoprotein
Acel_0686	ENOG4105C5W	Aldolase
Acel_0689	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Acel_0694	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Acel_0696	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Acel_0697	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Acel_0698	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Acel_0700	ENOG4105EJ5	oxidoreductase gamma subunit
Acel_0701	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Acel_0702	ENOG4105DDK	oxidoreductase, beta subunit
Acel_0705	ENOG4105C01	Dihydroxy-acid dehydratase
Acel_0706	ENOG4105C7K	acetolactate synthase
Acel_0707	ENOG4108ZP8	Acetolactate synthase small subunit
Acel_0708	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Acel_0709	ENOG4108JQ1	Dehydrogenase
Acel_0710	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Acel_0711	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Acel_0712	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Acel_0713	ENOG4105ERH	Fumarylacetoacetate hydrolase
Acel_0714	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Acel_0717	ENOG4105C2J	ABC transporter
Acel_0718	ENOG4105CNN	ABC, transporter
Acel_0719	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
Acel_0720	ENOG4107EDW	L-fucose operon activator
Acel_0721	ENOG41061GT	Aldolase
Acel_0723	ENOG4105QE3	oxidoreductase
Acel_0726	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Acel_0727	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acel_0728	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Acel_0729	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Acel_0733	ENOG4105C8N	cysteinyl-tRNA synthetase
Acel_0735	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Acel_0736	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Acel_0737	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Acel_0738	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Acel_0739	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Acel_0741	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Acel_0742	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Acel_0744	ENOG4105CJ1	ABC, transporter
Acel_0745	ENOG4105HAC	ABC-2 type transporter
Acel_0747	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Acel_0748	ENOG4105DFF	Rod shape-determining protein mreb
Acel_0751	ENOG4105CJN	penicillin-binding protein
Acel_0752	ENOG4105CNI	cell division protein FtsW
Acel_0755	ENOG4105C03	ribonuclease
Acel_0756	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Acel_0757	ENOG4105K46	50S ribosomal protein l27
Acel_0758	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Acel_0759	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Acel_0761	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Acel_0762	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Acel_0766	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Acel_0767	ENOG4108SEA	Esterase
Acel_0768	ENOG4105D9G	High-affinity
Acel_0769	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Acel_0771	ENOG4105C8T	Leucyl-tRNA synthetase
Acel_0772	ENOG4105EPR	degv family
Acel_0773	ENOG4105KQC	Competence protein
Acel_0776	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Acel_0778	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Acel_0783	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Acel_0784	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Acel_0788	ENOG4107YU2	histidine triad (hIT) protein
Acel_0790	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Acel_0794	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Acel_0795	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
Acel_0796	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Acel_0798	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
Acel_0801	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Acel_0802	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Acel_0805	ENOG4105JAB	phenazine biosynthesis protein, phzf family
Acel_0816	ENOG4105C0D	helicase
Acel_0823	ENOG4105BZU	Histidine kinase
Acel_0825	ENOG410900G	Protein of unknown function (DUF421)
Acel_0828	ENOG4105D58	Diguanylate phosphodiesterase
Acel_0829	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
Acel_0830	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
Acel_0831	ENOG4105DTJ	flagellar hook-associated protein
Acel_0832	ENOG4105E1Q	flagellar hook-associated protein
Acel_0838	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Acel_0839	ENOG4108ZC9	flagellar basal-body rod protein flgc
Acel_0840	ENOG41084Q6	flagellar hook-basal body complex protein fliE
Acel_0841	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
Acel_0842	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Acel_0846	ENOG4105E4C	Lytic transglycosylase catalytic
Acel_0849	ENOG4105BZE	flagellar hook protein, FlgE
Acel_0851	ENOG4105E14	MotA TolQ exbB proton channel
Acel_0852	ENOG4106VK6	Flagellar motor protein
Acel_0854	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Acel_0855	ENOG4105DD5	Flagellar motor switch protein
Acel_0857	ENOG4105CN7	Flagellar biosynthetic protein FliP
Acel_0858	ENOG4105VS8	Flagellar biosynthetic protein fliq
Acel_0859	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Acel_0860	ENOG4105D00	flagellar biosynthetic protein flhB
Acel_0861	ENOG4105D7B	Flagellar biosynthesis protein flha
Acel_0866	ENOG4105CAY	ferredoxin--nadp reductase
Acel_0870	ENOG4105ETE	Transcriptional regulator (LacI family
Acel_0871	ENOG4105EF1	ribulokinase
Acel_0873	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
Acel_0876	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Acel_0883	ENOG4105ES4	Nitrilase
Acel_0885	ENOG4105KME	endoribonuclease L-psp
Acel_0887	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
Acel_0896	ENOG4108XHQ	(2Fe-2S)-binding domain protein
Acel_0897	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
Acel_0898	ENOG4105ZXK	Dehydrogenase
Acel_0902	ENOG4105CVJ	phosphoglycerate mutase
Acel_0905	ENOG4105DEI	Mannitol dehydrogenase
Acel_0909	ENOG4105C0Z	ABC transporter
Acel_0910	ENOG4108IV0	ABC, transporter
Acel_0912	ENOG4108V1U	phospholipid-binding protein
Acel_0915	ENOG4105KHU	inner membrane protein YohD
Acel_0917	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Acel_0918	ENOG4105C4K	Nad synthetase
Acel_0919	ENOG4105C5F	glutamine synthetase
Acel_0920	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Acel_0926	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Acel_0927	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Acel_0932	ENOG4105BZU	Histidine kinase
Acel_0937	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Acel_0938	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Acel_0939	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Acel_0941	ENOG4108YZT	Adenosylcobinamide kinase
Acel_0943	ENOG4108JJB	ABC transporter
Acel_0944	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Acel_0948	ENOG4105CPC	Aldo Keto reductase
Acel_0952	ENOG4105D0M	Protease HtpX homolog
Acel_0956	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
Acel_0957	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Acel_0958	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
Acel_0961	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Acel_0962	ENOG4107EUI	c reductase, iron-sulfur
Acel_0963	ENOG4107UDY	cytochrome C
Acel_0964	ENOG4105CCU	oxidase (Subunit III)
Acel_0966	ENOG4107S1N	anthranilate phosphoribosyltransferase
Acel_0971	ENOG4105K4H	Nlp p60 protein
Acel_0972	ENOG4105JNK	Glycosyl transferase (Group 1
Acel_0974	ENOG4105BZU	Histidine kinase
Acel_0979	ENOG4105DKQ	ROK family
Acel_0982	ENOG4105F6E	Acyl-transferase
Acel_0983	ENOG4105CTQ	phosphohexokinase
Acel_0984	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
Acel_0985	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Acel_0987	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Acel_0990	ENOG4107Y5I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Acel_0992	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Acel_1000	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Acel_1001	ENOG4108V6E	Cell division protein mraZ
Acel_1002	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Acel_1004	ENOG4105CJN	penicillin-binding protein
Acel_1005	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Acel_1007	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Acel_1008	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Acel_1010	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Acel_1011	ENOG4105DFU	Cell wall formation (By similarity)
Acel_1012	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Acel_1013	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Acel_1014	ENOG4105DFA	alanine racemase domain protein
Acel_1017	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Acel_1021	ENOG41082RJ	Hydrogenase nickel insertion protein HypA
Acel_1024	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
Acel_1027	ENOG4107VQS	DivIVA family
Acel_1029	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Acel_1030	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Acel_1031	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Acel_1034	ENOG4107ZED	Uncharacterised protein family UPF0047
Acel_1035	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Acel_1037	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Acel_1040	ENOG4105CHR	reductase
Acel_1042	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Acel_1043	ENOG4105H1N	peptidase, M24
Acel_1045	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Acel_1046	ENOG4108JYK	Dehydrogenase
Acel_1047	ENOG4105CPP	Dehydrogenase, E1 component
Acel_1050	ENOG4105C2J	ABC transporter
Acel_1052	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
Acel_1053	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Acel_1058	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Acel_1059	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Acel_1060	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Acel_1061	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Acel_1062	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Acel_1063	ENOG4107QN1	sodium solute
Acel_1065	ENOG4105DY9	regulatoR
Acel_1067	ENOG4106HK8	GPR1 FUN34 yaaH family protein
Acel_1068	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Acel_1069	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Acel_1070	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Acel_1071	ENOG4105CRQ	synthase (Component I)
Acel_1073	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Acel_1074	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Acel_1075	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Acel_1076	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Acel_1078	ENOG4105CBC	glutamate synthase
Acel_1083	ENOG4105C32	Amino acid ABC transporter (Permease)
Acel_1084	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Acel_1085	ENOG4105C0Z	ABC transporter
Acel_1086	ENOG4108IV0	ABC, transporter
Acel_1091	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Acel_1096	ENOG4105C5F	glutamine synthetase
Acel_1099	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Acel_1101	ENOG4105NBF	ammecr1 domain protein
Acel_1102	ENOG4105ERH	Fumarylacetoacetate hydrolase
Acel_1106	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Acel_1109	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Acel_1110	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Acel_1111	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Acel_1112	ENOG4105CHW	UPF0052 protein
Acel_1113	ENOG4105CIE	May be required for sporulation (By similarity)
Acel_1114	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Acel_1115	ENOG4105BZA	Phosphoglycerate kinase
Acel_1120	ENOG4108JQ7	(ABC) transporter
Acel_1122	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
Acel_1125	ENOG4107QP8	phosphohexose isomerase
Acel_1126	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Acel_1127	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Acel_1128	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Acel_1129	ENOG4105DAG	ROK family
Acel_1130	ENOG4108HWW	ABC transporter
Acel_1131	ENOG4105C2J	ABC transporter
Acel_1137	ENOG4105C3K	feS assembly ATPase SufC
Acel_1138	ENOG4105C9B	Cysteine desulfurase
Acel_1139	ENOG4108UNV	SUF system FeS assembly protein, NifU family
Acel_1140	ENOG4105VG1	fes assembly suf system protein
Acel_1142	ENOG4105BZ1	(ABC) transporter
Acel_1143	ENOG4105BZP	glycoside hydrolase 15-related
Acel_1145	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Acel_1147	ENOG4105WKW	Pfam:DUF1458
Acel_1152	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Acel_1153	ENOG4106770	Is able to cleave peptidoglycan (By similarity)
Acel_1154	ENOG4105DKW	ABC transporter
Acel_1157	ENOG4105FAA	peptidase M23
Acel_1160	ENOG4105FCS	tRNA rRNA methyltransferase
Acel_1161	ENOG4105BZU	Histidine kinase
Acel_1162	ENOG4106UW1	Major Facilitator superfamily
Acel_1164	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
Acel_1165	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Acel_1168	ENOG4105CPC	Aldo Keto reductase
Acel_1172	ENOG4105C8N	cysteinyl-tRNA synthetase
Acel_1174	ENOG4105C3R	Methionine synthase
Acel_1175	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Acel_1178	ENOG4107RBB	ABC transporter, permease
Acel_1179	ENOG4105C19	ABC transporter
Acel_1184	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
Acel_1185	ENOG4105PTV	Nudix Hydrolase
Acel_1186	ENOG4105E5F	proteasome
Acel_1187	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
Acel_1188	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
Acel_1189	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
Acel_1191	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
Acel_1192	ENOG4105CEY	Amp-dependent synthetase and ligase
Acel_1193	ENOG4105C1G	acyl-Coa dehydrogenase
Acel_1197	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
Acel_1198	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Acel_1204	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Acel_1205	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Acel_1207	ENOG4105HFS	5'-3' exonuclease
Acel_1208	ENOG4105C1G	acyl-Coa dehydrogenase
Acel_1210	ENOG4107R05	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Acel_1211	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
Acel_1212	ENOG4105Q70	
Acel_1213	ENOG4108RTU	Aldolase
Acel_1218	ENOG4105DJ2	Major Facilitator Superfamily
Acel_1222	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Acel_1233	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Acel_1234	ENOG4105CAT	Cytidine monophosphate kinase
Acel_1235	ENOG4105EVN	Prephenate dehydrogenase
Acel_1237	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Acel_1238	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Acel_1239	ENOG4108Z4T	Peptidase M50
Acel_1243	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Acel_1245	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Acel_1246	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Acel_1250	ENOG4105DSU	hydrolase
Acel_1254	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Acel_1255	ENOG4108VX5	3-methyladenine DNA glycosylase
Acel_1256	ENOG4105CH7	arginosuccinase
Acel_1257	ENOG4105CDH	Citrulline--aspartate ligase
Acel_1258	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Acel_1259	ENOG4105DBV	ornithine carbamoyltransferase
Acel_1261	ENOG4105CAS	nag kinase
Acel_1262	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Acel_1263	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Acel_1264	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Acel_1265	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Acel_1267	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Acel_1268	ENOG41084BS	50S ribosomal protein L35
Acel_1269	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Acel_1270	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Acel_1271	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Acel_1272	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Acel_1276	ENOG4105DJV	ribulose-phosphate 3-epimerase
Acel_1278	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Acel_1279	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Acel_1280	ENOG4105CJP	fad dependent oxidoreductase
Acel_1281	ENOG4105D38	putrescine abc transporter
Acel_1282	ENOG4105F38	ABC transporter, permease
Acel_1284	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Acel_1285	ENOG4105C26	Dehydrogenase
Acel_1287	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Acel_1290	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Acel_1292	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Acel_1293	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Acel_1295	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Acel_1296	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Acel_1297	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Acel_1298	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Acel_1299	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Acel_1300	ENOG4105CD3	dihydroorotase
Acel_1301	ENOG4105CXT	aspartate transcarbamylase
Acel_1302	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Acel_1304	ENOG410803B	Involved in the transcription termination process (By similarity)
Acel_1305	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Acel_1306	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Acel_1307	ENOG4105D49	3-dehydroquinate synthase
Acel_1308	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Acel_1309	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Acel_1318	ENOG4106855	Competence protein
Acel_1319	ENOG4106855	Competence protein
Acel_1321	ENOG4105CZX	twitching motility protein
Acel_1322	ENOG4107QHF	type ii secretion system protein e
Acel_1327	ENOG4105E2X	shikimate dehydrogenase
Acel_1329	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Acel_1330	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Acel_1334	ENOG4105C9M	aspartyl-trna synthetase
Acel_1335	ENOG4105CUT	histidyl-tRNA synthetase
Acel_1337	ENOG41081K0	peptidylprolyl cis-trans isomerase
Acel_1338	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Acel_1339	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Acel_1340	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Acel_1343	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Acel_1344	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Acel_1345	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Acel_1346	ENOG4105CDY	transcriptional regulatory protein
Acel_1347	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Acel_1348	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Acel_1353	ENOG4105E2K	Glycosyl transferase (Group 1
Acel_1354	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
Acel_1355	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
Acel_1358	ENOG4105C22	threonyL-tRNA synthetase
Acel_1359	ENOG4105ETE	Transcriptional regulator (LacI family
Acel_1361	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Acel_1362	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Acel_1367	ENOG4105CJ1	ABC, transporter
Acel_1377	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
Acel_1378	ENOG4105DQE	DNA ligase
Acel_1379	ENOG4105E0X	reductase
Acel_1381	ENOG4105C1Q	protoporphyrinogen oxidase
Acel_1382	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Acel_1385	ENOG4108IUX	(ABC) transporter
Acel_1387	ENOG4105BZU	Histidine kinase
Acel_1390	ENOG4105WH1	Two component transcriptional regulator luxr family
Acel_1391	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
Acel_1393	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Acel_1394	ENOG4107QM5	aconitate hydratase
Acel_1396	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Acel_1397	ENOG4105C0X	amino acid
Acel_1398	ENOG4107VEG	TrkA-N domain protein
Acel_1402	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Acel_1406	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Acel_1407	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Acel_1417	ENOG4105KHC	sulfurtransferase
Acel_1420	ENOG4105BZU	Histidine kinase
Acel_1421	ENOG4105D0M	Protease HtpX homolog
Acel_1422	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Acel_1423	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
Acel_1425	ENOG4105C28	cystathionine
Acel_1427	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Acel_1430	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acel_1434	ENOG4105BZU	Histidine kinase
Acel_1439	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
Acel_1440	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
Acel_1441	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
Acel_1442	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
Acel_1443	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
Acel_1444	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Acel_1446	ENOG4105C8N	cysteinyl-tRNA synthetase
Acel_1448	ENOG4105BZU	Histidine kinase
Acel_1449	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Acel_1451	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Acel_1452	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Acel_1454	ENOG4105D9R	oxidoreductase
Acel_1457	ENOG4105EXC	Acyl-transferase
Acel_1465	ENOG4105CPU	Monooxygenase
Acel_1470	ENOG4105CQB	FAD linked oxidase domain protein
Acel_1474	ENOG4107Y70	Heat shock protein
Acel_1476	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Acel_1477	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Acel_1479	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Acel_1481	ENOG4105BZU	Histidine kinase
Acel_1482	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Acel_1483	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Acel_1484	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Acel_1486	ENOG4105C99	atpase involved in dna repair
Acel_1487	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Acel_1488	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Acel_1490	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Acel_1491	ENOG4105KC9	Modulates RecA activity (By similarity)
Acel_1492	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Acel_1494	ENOG4105NAF	rna polymerase sigma factor
Acel_1496	ENOG4107QRT	dEAD DEAH box helicase
Acel_1497	ENOG4105CEV	competence damage-inducible protein
Acel_1499	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Acel_1501	ENOG4107QZI	cell division protein FtsK
Acel_1502	ENOG4105CN5	Metallo-Beta-Lactamase
Acel_1503	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Acel_1504	ENOG4107V6K	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Acel_1506	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Acel_1507	ENOG4105C1V	Peptidase, M16
Acel_1508	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Acel_1509	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Acel_1512	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Acel_1513	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Acel_1515	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Acel_1518	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
Acel_1519	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Acel_1522	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Acel_1523	ENOG4105DZP	Membrane-associated zinc metalloprotease
Acel_1532	ENOG4105EP9	oxidoreductase
Acel_1533	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Acel_1536	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Acel_1537	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Acel_1538	ENOG4105KNE	Phosphatidate cytidylyltransferase
Acel_1539	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Acel_1540	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Acel_1541	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Acel_1542	ENOG4105CE9	30S ribosomal protein S2
Acel_1546	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acel_1547	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Acel_1549	ENOG4105C0P	Mg chelatase subunit ChlI
Acel_1550	ENOG41080R2	UPF0102 protein
Acel_1551	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
Acel_1554	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Acel_1557	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Acel_1558	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Acel_1559	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Acel_1560	ENOG41082KU	UPF0109 protein
Acel_1561	ENOG4105K5M	30s ribosomal protein S16
Acel_1564	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Acel_1572	ENOG4108375	Acylphosphatase (EC 3.6.1.7)
Acel_1573	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Acel_1574	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Acel_1575	ENOG41084BZ	50S ribosomal protein L32
Acel_1578	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Acel_1579	ENOG4106H78	methyltransferase
Acel_1581	ENOG4105DP4	dak2 domain fusion protein ylov
Acel_1582	ENOG4105VB9	50S ribosomal protein l28
Acel_1583	ENOG4105DWF	phosphomethylpyrimidine kinase
Acel_1586	ENOG4105CPF	Cell wall formation (By similarity)
Acel_1587	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Acel_1589	ENOG4105K70	DNA-binding protein
Acel_1590	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Acel_1591	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Acel_1592	ENOG41069M3	Transcriptional regulator
Acel_1594	ENOG41062D9	Histidine kinase
Acel_1595	ENOG4105ETX	regulatoR
Acel_1598	ENOG4108YZG	isomerase
Acel_1605	ENOG4105BZU	Histidine kinase
Acel_1606	ENOG4105ETX	regulatoR
Acel_1608	ENOG4108Z9K	Osmotically inducible protein
Acel_1611	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
Acel_1616	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Acel_1619	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
Acel_1626	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Acel_1627	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Acel_1628	ENOG4108Z5K	methylglyoxal synthase
Acel_1629	ENOG4108W2P	Methyl-accepting chemotaxis
Acel_1631	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
Acel_1635	ENOG4107RCH	Diaminopropionate ammonia-lyase
Acel_1640	ENOG4105CDA	abc transporter atp-binding protein
Acel_1641	ENOG4107R0W	ABC transporter
Acel_1642	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
Acel_1644	ENOG4105DMN	coenzyme A transferase
Acel_1645	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
Acel_1648	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Acel_1649	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
Acel_1650	ENOG4105VPX	protein, conserved in bacteria
Acel_1657	ENOG4105CR4	methylisocitrate lyase
Acel_1659	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
Acel_1660	ENOG4108ZJI	phenylacetic acid degradation protein
Acel_1662	ENOG4105BZU	Histidine kinase
Acel_1665	ENOG4105EUJ	GTP cyclohydrolase i
Acel_1667	ENOG41085W3	Transposase
Acel_1670	ENOG4105DQE	DNA ligase
Acel_1674	ENOG4107WI4	Aldose-1-epimerase
Acel_1677	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Acel_1681	ENOG4105CPQ	Dehydrogenase
Acel_1683	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Acel_1684	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Acel_1685	ENOG4108RQ5	Beta-lactamase domain-containing protein
Acel_1686	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Acel_1691	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Acel_1695	ENOG4107S11	squalene-associated FAD-dependent desaturase
Acel_1697	ENOG4105EWU	Squalene--hopene cyclase
Acel_1699	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Acel_1701	ENOG4105CYP	glycoside hydrolase, family
Acel_1702	ENOG4108R5T	secreted protein
Acel_1704	ENOG4108UJU	UPF0301 protein
Acel_1705	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Acel_1709	ENOG4105KBX	Transcriptional regulator, TetR family
Acel_1711	ENOG4108KEZ	Dehydrogenase
Acel_1713	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acel_1714	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Acel_1715	ENOG4105CPC	Aldo Keto reductase
Acel_1716	ENOG4105C0H	protease
Acel_1717	ENOG4108RWI	nicotinamidase
Acel_1718	ENOG4105EGE	secreted protein
Acel_1723	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Acel_1724	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Acel_1725	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Acel_1728	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Acel_1729	ENOG4105CN1	protease
Acel_1730	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
Acel_1731	ENOG4105CAK	Cell division ATP-binding protein ftsE
Acel_1732	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Acel_1740	ENOG4105BZU	Histidine kinase
Acel_1741	ENOG4105EC2	ftsk spoIIIe
Acel_1743	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
Acel_1744	ENOG4107QZF	nitrite reductase NADPH large subunit
Acel_1745	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
Acel_1746	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Acel_1747	ENOG4107QND	Nitrite extrusion protein
Acel_1749	ENOG4105C7I	Dehydrogenase
Acel_1750	ENOG4105C26	Dehydrogenase
Acel_1759	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Acel_1760	ENOG4105WH1	Two component transcriptional regulator luxr family
Acel_1761	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
Acel_1763	ENOG4108T3R	lipoprotein lpqB
Acel_1764	ENOG4105BZU	Histidine kinase
Acel_1765	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Acel_1770	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
Acel_1771	ENOG4105C4R	Atp-dependent dna helicase
Acel_1773	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Acel_1776	ENOG4105ENA	helicase
Acel_1781	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Acel_1787	ENOG4108VYJ	response regulator receiver protein
Acel_1788	ENOG4105BZU	Histidine kinase
Acel_1789	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Acel_1792	ENOG4105YFD	chemotaxis, protein
Acel_1793	ENOG4105CBS	Chea signal transduction histidine kinase
Acel_1795	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
Acel_1798	ENOG4105ETE	Transcriptional regulator (LacI family
Acel_1799	ENOG4105C26	Dehydrogenase
Acel_1800	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
Acel_1801	ENOG4105DH8	myo-inositol catabolism
Acel_1803	ENOG4105D7K	pfkb domain protein
Acel_1804	ENOG4105FDP	GntR family transcriptional regulator
Acel_1805	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Acel_1807	ENOG4105CNN	ABC, transporter
Acel_1808	ENOG4105C2J	ABC transporter
Acel_1809	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Acel_1810	ENOG4105F0H	myo-inositol catabolism protein
Acel_1812	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
Acel_1814	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Acel_1815	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
Acel_1816	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
Acel_1818	ENOG4105CJW	magnesium transporter
Acel_1820	ENOG4108J5G	6-phosphogluconate dehydrogenase
Acel_1821	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Acel_1822	ENOG4107QPH	glycogen) synthase
Acel_1824	ENOG4105D1F	ATP-binding protein
Acel_1826	ENOG4105DU6	RNA polymerase
Acel_1829	ENOG4105MC2	DSBA oxidoreductase
Acel_1831	ENOG4105BZU	Histidine kinase
Acel_1832	ENOG4108KXV	response regulator
Acel_1834	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Acel_1836	ENOG4108UKI	Enoyl-CoA hydratase
Acel_1837	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Acel_1839	ENOG4105EEI	dihydropteroate synthase
Acel_1841	ENOG4108URH	decarboxylase
Acel_1843	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
Acel_1844	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Acel_1846	ENOG4105EJQ	L-serine dehydratase
Acel_1847	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Acel_1848	ENOG4108Z86	Glutamine amidotransferase
Acel_1849	ENOG4105CHR	reductase
Acel_1850	ENOG4105C26	Dehydrogenase
Acel_1851	ENOG4105C5F	glutamine synthetase
Acel_1852	ENOG41073TP	transcriptional regulator
Acel_1854	ENOG4105RD7	BadF BadG BcrA BcrD
Acel_1856	ENOG4108Z4U	Ferredoxin
Acel_1858	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Acel_1861	ENOG4105C3G	gtp-binding protein
Acel_1862	ENOG410842T	Pterin carbinolamine dehydratase
Acel_1865	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
Acel_1868	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
Acel_1869	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Acel_1872	ENOG4105C8Q	Methyl-accepting chemotaxis
Acel_1873	ENOG4105CBS	Chea signal transduction histidine kinase
Acel_1874	ENOG4105ETX	regulatoR
Acel_1875	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Acel_1876	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Acel_1879	ENOG4105C9Q	fumarate hydratase class II
Acel_1881	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Acel_1883	ENOG4105C7Z	Conserved Protein
Acel_1884	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Acel_1886	ENOG4105T1M	mycothiol conjugate amidase mca
Acel_1887	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Acel_1888	ENOG4105C7B	Threonine dehydratase
Acel_1893	ENOG4107KWJ	von Willebrand factor, type A
Acel_1898	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Acel_1905	ENOG4105BZU	Histidine kinase
Acel_1909	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Acel_1911	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Acel_1920	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Acel_1929	ENOG4107EF8	Glycosyl transferase (Group 1
Acel_1931	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Acel_1932	ENOG4107S6X	Glycosyl transferase, family 2
Acel_1934	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Acel_1939	ENOG4105D3Q	Sugar transferase
Acel_1941	ENOG4105D5U	fad dependent oxidoreductase
Acel_1943	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Acel_1944	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Acel_1945	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Acel_1946	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Acel_1947	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Acel_1948	ENOG4105EUB	pirin domain protein
Acel_1949	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Acel_1957	ENOG4107TSN	permease
Acel_1961	ENOG4105ME0	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor (By similarity)
Acel_1962	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
Acel_1964	ENOG4105MA4	psp1 domain protein
Acel_1970	ENOG4107QRG	dna polymerase iii
Acel_1971	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Acel_1972	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Acel_1973	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Acel_1975	ENOG4105WN5	stage II sporulation protein
Acel_1976	ENOG4108I5C	dEAD DEAH box helicase
Acel_1984	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Acel_1985	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
Acel_1990	ENOG4105D74	hydrolase
Acel_1997	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Acel_2004	ENOG4105BZ4	penicillin-binding protein
Acel_2005	ENOG4105KTH	gatB Yqey
Acel_2012	ENOG4105CFH	Aspartokinase
Acel_2015	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Acel_2018	ENOG4108Z6B	deaminase
Acel_2020	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Acel_2021	ENOG4105W8H	transhydrogenase (subunit alpha
Acel_2022	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Acel_2025	ENOG4107NHD	transcriptional regulator
Acel_2026	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
Acel_2032	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acel_2033	ENOG4106UDK	Cellulose-binding, family II
Acel_2045	ENOG4105I82	acetyl xylan esterase
Acel_2046	ENOG4105ETE	Transcriptional regulator (LacI family
Acel_2048	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Acel_2049	ENOG4108JP0	extracellular solute-binding protein family 1
Acel_2050	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
Acel_2051	ENOG4107SDU	Methyl-accepting chemotaxis
Acel_2052	ENOG4105C8N	cysteinyl-tRNA synthetase
Acel_2055	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
Acel_2071	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Acel_2074	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Acel_2075	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Acel_2076	ENOG410839H	phosphoribosylformylglycinamidine synthase
Acel_2083	ENOG4105CDU	Replicative dna helicase
Acel_2090	ENOG4107QHF	type ii secretion system protein e
Acel_2094	ENOG4105CH6	catalase
Acel_2098	ENOG4105EIP	mannose-6-phosphate isomerase
Acel_2099	ENOG4105BZU	Histidine kinase
Acel_2100	ENOG4105BZU	Histidine kinase
Acel_2102	ENOG4108VC7	Protein of unknown function (DUF2587)
Acel_2103	ENOG4108K4B	hydrolase
Acel_2104	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Acel_2105	ENOG4105CQC	Prephenate dehydratase
Acel_2109	ENOG41082VC	UPF0145 protein
Acel_2112	ENOG4105DHP	deoxycytidine triphosphate deaminase
Acel_2113	ENOG4105DF6	Fe-S oxidoreductase
Acel_2115	ENOG4105CFG	Acts as a chaperone (By similarity)
Acel_2116	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Acel_2117	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Acel_2118	ENOG4105KNI	merR family transcriptional Regulator
Acel_2119	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Acel_2120	ENOG4105D7K	pfkb domain protein
Acel_2122	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
Acel_2123	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Acel_2124	ENOG4105DQR	SNARE associated Golgi
Acel_2126	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Acel_2127	ENOG4105C12	Phosphoribosylglycinamide synthetase
Acel_2128	ENOG4105C83	adenylosuccinate lyase
Acel_2129	ENOG4105C8V	SAICAR synthetase
Acel_2130	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Acel_2131	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Acel_2133	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
Acel_2135	ENOG4105BZ4	penicillin-binding protein
Acel_2139	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Acel_2148	ENOG4105C3M	thioredoxin reductase
Acel_2149	ENOG4105K63	Thioredoxin
Acel_2152	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Acel_2153	ENOG4105CPF	Cell wall formation (By similarity)
Acel_2155	ENOG4107QJE	Chromosome Partitioning Protein
Acel_2156	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Acel_2158	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Acel_2161	ENOG41084CH	50S ribosomal protein l34