locus-tag	class	description
Aave_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Aave_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Aave_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Aave_0009	ENOG4108Z9K	Osmotically inducible protein
Aave_0011	ENOG4105D6E	homoserine dehydrogenase
Aave_0013	ENOG4105DVT	helicase
Aave_0016	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Aave_0017	ENOG4105CSW	GntR family transcriptional regulator
Aave_0019	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Aave_0020	ENOG4105K4H	Nlp p60 protein
Aave_0021	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Aave_0022	ENOG4105BZU	Histidine kinase
Aave_0025	ENOG4105DH7	May be involved in recombination (By similarity)
Aave_0026	ENOG4108JIC	nucleoside recognition domain protein
Aave_0031	ENOG4105CHU	acetyl-coa acetyltransferase
Aave_0034	ENOG4105C59	p-type ATPase
Aave_0035	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0041	ENOG4105ETX	regulatoR
Aave_0042	ENOG4105ECM	Sensor protein basS pmrB
Aave_0046	ENOG4108IY8	ABC, transporter
Aave_0047	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Aave_0048	ENOG4108K3A	Glutathione S-transferase
Aave_0049	ENOG4105KRS	Proteinase inhibitor
Aave_0051	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Aave_0052	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Aave_0053	ENOG4108NIW	Leucine export protein LeuE
Aave_0054	ENOG4107QJE	Chromosome Partitioning Protein
Aave_0059	ENOG4105BZ8	glutamate synthase
Aave_0063	ENOG4105IQ5	FAD linked oxidase domain protein
Aave_0067	ENOG4105EBR	Carboxylesterase
Aave_0068	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Aave_0070	ENOG41081F0	Precorrin-8x methylmutase
Aave_0071	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
Aave_0072	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
Aave_0074	ENOG4108P62	biosynthesis protein (CbiG)
Aave_0077	ENOG4105E4R	Precorrin-3B C17-methyltransferase
Aave_0078	ENOG4105NZG	Ferredoxin
Aave_0081	ENOG4107XWI	flavin reductase domain protein, FMN-binding
Aave_0085	ENOG4106TQH	Potential cysteine protease, which may play a central role after invasion of host cell (By similarity)
Aave_0095	ENOG4105CQB	FAD linked oxidase domain protein
Aave_0098	ENOG4108WBT	adenosyltransferase
Aave_0099	ENOG4105KA0	thioesterase Superfamily protein
Aave_0102	ENOG4105C2W	permease
Aave_0104	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0106	ENOG4108Z0R	Transferase
Aave_0112	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
Aave_0117	ENOG4108K0D	peptidase, M48
Aave_0119	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Aave_0121	ENOG4107QWB	Ornithine cyclodeaminase
Aave_0123	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Aave_0124	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Aave_0125	ENOG4107QMS	site-determining protein
Aave_0126	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Aave_0130	ENOG41081R7	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Aave_0131	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Aave_0138	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
Aave_0139	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Aave_0141	ENOG4105DJ9	glucan biosynthesis protein
Aave_0142	ENOG4105C7B	Threonine dehydratase
Aave_0144	ENOG4105CSU	acyl-Coa dehydrogenase
Aave_0148	ENOG4108RXX	maleylacetoacetate isomerase
Aave_0157	ENOG4105C0D	helicase
Aave_0168	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0172	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Aave_0173	ENOG4107TUY	Histidine kinase
Aave_0174	ENOG4105C3R	Methionine synthase
Aave_0175	ENOG4106NZI	LysR family Transcriptional regulator
Aave_0181	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Aave_0188	ENOG4105D82	Glutamate dehydrogenase
Aave_0190	ENOG4105CSR	polyphosphate kinase 2
Aave_0195	ENOG4108MP6	LysR family Transcriptional regulator
Aave_0198	ENOG4105DND	Transcriptional regulator
Aave_0204	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
Aave_0205	ENOG4107RP9	extracellular solute-binding protein, family 3
Aave_0208	ENOG4105CDA	abc transporter atp-binding protein
Aave_0209	ENOG4105E5Q	amino acid AbC transporter
Aave_0210	ENOG4105E5Q	amino acid AbC transporter
Aave_0214	ENOG4105C3R	Methionine synthase
Aave_0219	ENOG4105HSS	phospholipase C
Aave_0220	ENOG4105BZU	Histidine kinase
Aave_0224	ENOG4105DP0	ferredoxin-NADP reductase
Aave_0225	ENOG4105CBN	LysR family transcriptional regulator
Aave_0227	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0230	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Aave_0231	ENOG4105C0P	Mg chelatase subunit ChlI
Aave_0241	ENOG4105CS6	Rhs element vgr protein
Aave_0242	ENOG4105EU8	FAD linked oxidase domain protein
Aave_0244	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Aave_0252	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
Aave_0253	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Aave_0255	ENOG4105DEF	Extracellular solute-binding protein, family 5
Aave_0259	ENOG4108K3A	Glutathione S-transferase
Aave_0260	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Aave_0262	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Aave_0264	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Aave_0272	ENOG4105EGI	Transcriptional regulator
Aave_0273	ENOG4105CBP	Major Facilitator
Aave_0274	ENOG4105E0F	Histidine kinase
Aave_0275	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Aave_0276	ENOG4105EYM	Major Facilitator superfamily
Aave_0280	ENOG4105D0M	Protease HtpX homolog
Aave_0281	ENOG4107QPK	)-transporter
Aave_0282	ENOG4105C5X	domain protein
Aave_0285	ENOG4105HEI	LysR family (Transcriptional regulator
Aave_0286	ENOG4105F27	Major Facilitator
Aave_0287	ENOG4105CV8	reductase
Aave_0288	ENOG4105CGK	Exodeoxyribonuclease III
Aave_0289	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Aave_0291	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Aave_0292	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Aave_0293	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Aave_0294	ENOG4105DFF	Rod shape-determining protein mreb
Aave_0296	ENOG4105VQ7	Rod shape-determining protein MreD
Aave_0297	ENOG4105CJN	penicillin-binding protein
Aave_0300	ENOG4105E5Q	amino acid AbC transporter
Aave_0301	ENOG4105EAB	amino acid AbC transporter
Aave_0302	ENOG4105EJQ	L-serine dehydratase
Aave_0303	ENOG4105JQN	Transcriptional regulator
Aave_0307	ENOG4105DHJ	ABC, transporter
Aave_0312	ENOG4105VDW	Csbd family
Aave_0316	ENOG4105CT7	inner membrane cred family protein
Aave_0317	ENOG4105EB3	Histidine kinase
Aave_0318	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Aave_0319	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
Aave_0320	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Aave_0322	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Aave_0324	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
Aave_0325	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Aave_0326	ENOG4105D7N	magnesium and cobalt transport protein CorA
Aave_0327	ENOG4105D52	delta-aminolevulinic acid dehydratase
Aave_0328	ENOG4108YXA	Membrane
Aave_0331	ENOG4105DHZ	alpha beta
Aave_0332	ENOG4105DZ1	carboxypeptidase
Aave_0333	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Aave_0334	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Aave_0335	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Aave_0336	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Aave_0337	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Aave_0338	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Aave_0339	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Aave_0340	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Aave_0341	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Aave_0342	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Aave_0343	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Aave_0344	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Aave_0345	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Aave_0346	ENOG41084PQ	50s ribosomal protein l29
Aave_0347	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Aave_0350	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Aave_0353	ENOG41080Z8	PHOSPHOCARRIER protein
Aave_0354	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Aave_0355	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Aave_0356	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Aave_0357	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
Aave_0358	ENOG4105C08	Histidine kinase
Aave_0359	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
Aave_0362	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Aave_0363	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Aave_0364	ENOG4108Z43	UPF0250 protein
Aave_0366	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
Aave_0367	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Aave_0368	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Aave_0369	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Aave_0370	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Aave_0371	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Aave_0372	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Aave_0373	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Aave_0374	ENOG4107T0X	DNA ligase
Aave_0375	ENOG4107T0X	DNA ligase
Aave_0376	ENOG4107QRT	dEAD DEAH box helicase
Aave_0387	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Aave_0388	ENOG4105BZS	acriflavin resistance protein
Aave_0389	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Aave_0403	ENOG4105E7A	Glutamine amidotransferase
Aave_0404	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Aave_0405	ENOG41084KP	4-oxalocrotonate tautomerase
Aave_0407	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0408	ENOG4107QP3	malate synthase g
Aave_0411	ENOG4105DZG	Dehydrogenase
Aave_0414	ENOG4105C75	arginyL-tRNA synthetase
Aave_0416	ENOG4108Z33	Thiol disulfide Interchange Protein
Aave_0418	ENOG4108IUZ	ABC transporter
Aave_0419	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Aave_0420	ENOG4105KAV	tspo and mbr like protein
Aave_0421	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0422	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Aave_0426	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Aave_0427	ENOG4105CHH	sulfate transporter
Aave_0428	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0430	ENOG4108ZAI	phosphatidylglycerophosphatase a
Aave_0432	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Aave_0434	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
Aave_0437	ENOG4105NWN	ApaG protein
Aave_0438	ENOG4105DJV	ribulose-phosphate 3-epimerase
Aave_0440	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Aave_0463	ENOG4108JIR	Flagellum-specific ATP synthase
Aave_0466	ENOG4107Y59	type iii secretion
Aave_0474	ENOG4105K44	type iii secretion
Aave_0476	ENOG4105E4C	Lytic transglycosylase catalytic
Aave_0481	ENOG4105CS6	Rhs element vgr protein
Aave_0484	ENOG4105DFP	Integrase
Aave_0492	ENOG4105W5Q	DNA repair protein (RadC
Aave_0497	ENOG4105CS6	Rhs element vgr protein
Aave_0499	ENOG4105CNA	YD repeat protein
Aave_0518	ENOG4105C0B	DNA polymerase III (alpha subunit)
Aave_0557	ENOG4105NI8	Cytosine-specific methyltransferase
Aave_0558	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Aave_0566	ENOG4107QMS	site-determining protein
Aave_0579	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
Aave_0583	ENOG4105DDQ	anthranilate synthase
Aave_0584	ENOG410829K	Lysine exporter protein (Lyse ygga)
Aave_0585	ENOG4107QYG	anthranilate phosphoribosyltransferase
Aave_0586	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Aave_0587	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
Aave_0589	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Aave_0592	ENOG4105CPI	Metal Dependent Phosphohydrolase
Aave_0593	ENOG4105CB5	ATP-dependent DNA helicase recG
Aave_0594	ENOG4105C5Q	Transcriptional regulator
Aave_0596	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
Aave_0601	ENOG4105II7	pyrroline-5-carboxylate reductase
Aave_0602	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Aave_0603	ENOG4105E98	transcriptional regulator DeoR family
Aave_0604	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Aave_0605	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Aave_0607	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
Aave_0611	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Aave_0612	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Aave_0613	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Aave_0614	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Aave_0615	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Aave_0616	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Aave_0617	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Aave_0618	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Aave_0619	ENOG4105VPB	50S ribosomal protein L30
Aave_0620	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Aave_0621	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Aave_0622	ENOG41067V7	50S ribosomal protein L36
Aave_0623	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Aave_0624	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Aave_0625	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Aave_0626	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Aave_0627	ENOG4108ZT0	50S ribosomal protein l17
Aave_0628	ENOG4105R8A	Heat shock protein
Aave_0629	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Aave_0630	ENOG41082RQ	UPF0102 protein
Aave_0631	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Aave_0632	ENOG4105W4M	Transport-associated protein
Aave_0633	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Aave_0635	ENOG4105CZX	twitching motility protein
Aave_0636	ENOG4105IJJ	transcriptional regulator, crp fnr family
Aave_0637	ENOG4105CZX	twitching motility protein
Aave_0638	ENOG4105DFA	alanine racemase domain protein
Aave_0641	ENOG4106BRA	Membrane
Aave_0645	ENOG4105CQB	FAD linked oxidase domain protein
Aave_0649	ENOG4105BZU	Histidine kinase
Aave_0654	ENOG4105WH1	Two component transcriptional regulator luxr family
Aave_0657	ENOG4107ZSV	Receptor
Aave_0660	ENOG4105DQQ	Major facilitator superfamily MFS_1
Aave_0661	ENOG4105CRU	nitrate reductase, alpha subunit
Aave_0662	ENOG4108IUE	nitrate reductase beta subunit
Aave_0663	ENOG4105R3A	Nitrate reductase
Aave_0664	ENOG4105D0D	Nitrate reductase 2, gamma subunit
Aave_0665	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Aave_0669	ENOG4105NSG	hemerythrin hhe cation binding domain protein
Aave_0672	ENOG4105DFS	Conserved Protein
Aave_0676	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Aave_0680	ENOG4105FA0	parb-like partition protein
Aave_0687	ENOG4107QJE	Chromosome Partitioning Protein
Aave_0697	ENOG4105K6H	D-cysteine desulfhydrase
Aave_0698	ENOG4105ETT	transcriptional Regulator, LysR family
Aave_0699	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Aave_0700	ENOG4105F27	Major Facilitator
Aave_0704	ENOG4106UW1	Major Facilitator superfamily
Aave_0713	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
Aave_0715	ENOG4105CV8	reductase
Aave_0716	ENOG4108M0I	Transcriptional regulator
Aave_0717	ENOG4105C57	major facilitator superfamily
Aave_0722	ENOG4106NZI	LysR family Transcriptional regulator
Aave_0744	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Aave_0747	ENOG4108UT2	hemolysin iii
Aave_0749	ENOG4105BZU	Histidine kinase
Aave_0751	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Aave_0752	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
Aave_0754	ENOG4105C01	Dihydroxy-acid dehydratase
Aave_0755	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Aave_0757	ENOG4105EQ1	Transcriptional regulator
Aave_0759	ENOG4105CHJ	isochorismatase hydrolase
Aave_0767	ENOG4108J2R	molybdopterin oxidoreductase
Aave_0770	ENOG4105CH2	amidohydrolase
Aave_0772	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0775	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Aave_0777	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Aave_0781	ENOG4105DZS	Phenylacetate-CoA ligase
Aave_0782	ENOG4108IV0	ABC, transporter
Aave_0784	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Aave_0785	ENOG4105C32	Amino acid ABC transporter (Permease)
Aave_0786	ENOG4105C0Z	ABC transporter
Aave_0789	ENOG4105YGF	General secretion pathway protein
Aave_0791	ENOG4108M3P	Membrane
Aave_0792	ENOG4105I08	Pseudouridine synthase
Aave_0794	ENOG41061H0	Monooxygenase
Aave_0798	ENOG4105CYM	Glutathione S-transferase
Aave_0799	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Aave_0801	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Aave_0802	ENOG4105F32	YngK protein
Aave_0805	ENOG4105DR4	Methyltransferase
Aave_0806	ENOG4105BZU	Histidine kinase
Aave_0807	ENOG4105CKI	cobalamin synthesis protein
Aave_0808	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Aave_0810	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Aave_0811	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Aave_0812	ENOG4108V6E	Cell division protein mraZ
Aave_0813	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Aave_0815	ENOG4105CJN	penicillin-binding protein
Aave_0816	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Aave_0817	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
Aave_0818	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Aave_0819	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Aave_0820	ENOG4105CNI	cell division protein FtsW
Aave_0821	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Aave_0822	ENOG4105DFU	Cell wall formation (By similarity)
Aave_0823	ENOG4105CPF	Cell wall formation (By similarity)
Aave_0824	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
Aave_0825	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Aave_0826	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Aave_0827	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Aave_0829	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Aave_0831	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0833	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Aave_0834	ENOG4105KNE	Phosphatidate cytidylyltransferase
Aave_0839	ENOG4108K2P	TRANSCRIPTIONal
Aave_0840	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
Aave_0841	ENOG4105E2X	shikimate dehydrogenase
Aave_0845	ENOG4105IPS	esterase
Aave_0846	ENOG4105CNI	cell division protein FtsW
Aave_0849	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Aave_0850	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Aave_0852	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Aave_0854	ENOG4105DFU	Cell wall formation (By similarity)
Aave_0856	ENOG4107QX9	Thiol disulfide interChange protein
Aave_0857	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Aave_0858	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Aave_0859	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Aave_0863	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Aave_0864	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Aave_0866	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Aave_0867	ENOG4107TUY	Histidine kinase
Aave_0870	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Aave_0872	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Aave_0874	ENOG4107WP9	Histidine kinase
Aave_0875	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Aave_0878	ENOG4105FBW	Monooxygenase
Aave_0879	ENOG4108UZX	fmn reductase
Aave_0881	ENOG4107SM7	Transcriptional regulator
Aave_0882	ENOG4105E39	Enoyl-CoA hydratase
Aave_0884	ENOG4105T95	Thiol disulfide interChange protein
Aave_0885	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
Aave_0886	ENOG4105QVC	MOSC domain-containing protein
Aave_0887	ENOG4105C3G	gtp-binding protein
Aave_0890	ENOG4108IJ8	ABC transporter
Aave_0891	ENOG4105FR1	rard protein
Aave_0892	ENOG4105W39	Membrane
Aave_0893	ENOG4105BZU	Histidine kinase
Aave_0894	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Aave_0895	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
Aave_0896	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Aave_0898	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Aave_0899	ENOG4105DWF	phosphomethylpyrimidine kinase
Aave_0900	ENOG4105VCQ	rubredoxin
Aave_0901	ENOG4108UNF	response regulator
Aave_0902	ENOG4105M3Z	response regulator
Aave_0903	ENOG4108V3W	Chemotaxis protein, CheW
Aave_0904	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0905	ENOG4105CBS	Chea signal transduction histidine kinase
Aave_0907	ENOG4108UJU	UPF0301 protein
Aave_0908	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Aave_0909	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Aave_0910	ENOG4105CXT	aspartate transcarbamylase
Aave_0911	ENOG4105CD3	dihydroorotase
Aave_0913	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Aave_0914	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
Aave_0916	ENOG4107QHF	type ii secretion system protein e
Aave_0917	ENOG4105GVR	general secretion pathway protein D
Aave_0924	ENOG4105WMT	general secretion pathway protein h
Aave_0925	ENOG4108VAU	general secretion pathway protein G
Aave_0928	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Aave_0929	ENOG4105C7B	Threonine dehydratase
Aave_0930	ENOG4108UKZ	OsmC family
Aave_0931	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
Aave_0932	ENOG4108Z9W	Outer membrane porin
Aave_0934	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Aave_0935	ENOG4105CH2	amidohydrolase
Aave_0936	ENOG4105DEF	Extracellular solute-binding protein, family 5
Aave_0937	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Aave_0938	ENOG4105C3U	ABC transporter
Aave_0939	ENOG4108JQ7	(ABC) transporter
Aave_0940	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_0942	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
Aave_0943	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Aave_0944	ENOG4107QP8	phosphohexose isomerase
Aave_0945	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Aave_0946	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Aave_0949	ENOG4107QQG	Dehydrogenase
Aave_0950	ENOG4107R5Z	Oxidoreductase domain protein
Aave_0951	ENOG4105J5G	Transferase hexapeptide repeat containing protein
Aave_0952	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Aave_0953	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Aave_0954	ENOG4105MFV	ABC-2 type transporter
Aave_0955	ENOG4105EY8	ABC transporter
Aave_0956	ENOG4105DVA	methyltransferase
Aave_0957	ENOG4105CPK	Glycosyl transferase (Group 1
Aave_0959	ENOG4105CAQ	asparagine synthetase
Aave_0960	ENOG4107EF8	Glycosyl transferase (Group 1
Aave_0961	ENOG4105CAQ	asparagine synthetase
Aave_0964	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
Aave_0966	ENOG4105BZ8	glutamate synthase
Aave_0967	ENOG4107SJI	Dehydrogenase
Aave_0968	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
Aave_0969	ENOG4105CD3	dihydroorotase
Aave_0970	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
Aave_0976	ENOG4107RH7	Nicotinate phosphoribosyltransferase
Aave_0979	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Aave_0981	ENOG4105D1S	lipid A biosynthesis
Aave_0983	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Aave_0984	ENOG4106RE7	Cytochrome
Aave_0985	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
Aave_0986	ENOG4105CRE	cytochrome C
Aave_0987	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
Aave_0988	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
Aave_0992	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Aave_0994	ENOG4105XQ6	frataxin-like protein
Aave_0995	ENOG4108JQC	penicillin-binding protein 1A
Aave_1000	ENOG4105E4G	Type IV pilus
Aave_1002	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Aave_1003	ENOG4105D49	3-dehydroquinate synthase
Aave_1004	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Aave_1010	ENOG4106TNF	Periplasmic binding protein
Aave_1011	ENOG4105E5Q	amino acid AbC transporter
Aave_1012	ENOG4105CDA	abc transporter atp-binding protein
Aave_1013	ENOG4105DHJ	ABC, transporter
Aave_1014	ENOG4105CY3	ABC transporter, permease
Aave_1015	ENOG4107PE3	Mammalian cell entry related domain protein
Aave_1016	ENOG410903C	(LipO)protein
Aave_1019	ENOG4105DA5	(ABC) transporter
Aave_1020	ENOG4105E3A	(ABC) transporter
Aave_1021	ENOG4105VFK	BolA family
Aave_1022	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Aave_1023	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Aave_1024	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Aave_1031	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Aave_1032	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Aave_1033	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Aave_1034	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Aave_1038	ENOG4108I69	Glycosyl transferases group 1
Aave_1044	ENOG4105CMR	udp-glucose 4-epimerase
Aave_1045	ENOG4105CK2	sodium dicarboxylate symporter
Aave_1047	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Aave_1048	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Aave_1049	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
Aave_1052	ENOG4107YU2	histidine triad (hIT) protein
Aave_1053	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Aave_1054	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
Aave_1055	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Aave_1058	ENOG4105CSH	Transporter
Aave_1059	ENOG4107QNR	UPF0135 protein
Aave_1063	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Aave_1064	ENOG4105C0H	protease
Aave_1065	ENOG4105EYA	deoxyribonuclease
Aave_1067	ENOG4105I7M	spermidine synthase
Aave_1068	ENOG4107QHF	type ii secretion system protein e
Aave_1078	ENOG4108JU3	Alkyl hydroperoxide reductase
Aave_1080	ENOG4105CHR	reductase
Aave_1081	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_1082	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
Aave_1086	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Aave_1089	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
Aave_1091	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Aave_1092	ENOG4105D7T	ABC transporter
Aave_1095	ENOG4105C6K	Malic enzyme
Aave_1098	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
Aave_1099	ENOG4107YCY	Transcriptional regulator
Aave_1100	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_1101	ENOG4105CK2	sodium dicarboxylate symporter
Aave_1106	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Aave_1109	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Aave_1112	ENOG4107YCY	Transcriptional regulator
Aave_1114	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Aave_1116	ENOG4105VT2	5-hydroxyisourate hydrolase
Aave_1120	ENOG4105BZU	Histidine kinase
Aave_1123	ENOG4105KME	endoribonuclease L-psp
Aave_1125	ENOG4108Z9W	Outer membrane porin
Aave_1127	ENOG4105BZU	Histidine kinase
Aave_1129	ENOG4105C7W	Xanthine dehydrogenase
Aave_1132	ENOG4105C2J	ABC transporter
Aave_1133	ENOG4105UIB	(ABC) transporter
Aave_1138	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Aave_1141	ENOG4105C5I	Dehydrogenase
Aave_1144	ENOG4105DHP	deoxycytidine triphosphate deaminase
Aave_1147	ENOG4105CGZ	zinc metallopeptidase
Aave_1148	ENOG4105C1J	atp-dependent rna helicase
Aave_1149	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Aave_1150	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
Aave_1151	ENOG4107QM5	aconitate hydratase
Aave_1152	ENOG4105BZU	Histidine kinase
Aave_1153	ENOG4105BZU	Histidine kinase
Aave_1155	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
Aave_1157	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
Aave_1158	ENOG4108YXU	transcriptional regulator AsnC family
Aave_1159	ENOG4105PI0	Ferredoxin
Aave_1161	ENOG4105CE1	Ferrous iron transport protein b
Aave_1163	ENOG4105DBV	ornithine carbamoyltransferase
Aave_1164	ENOG4105C8Y	Acetylornithine aminotransferase
Aave_1166	ENOG4105DWT	malate dehydrogenase (quinone)
Aave_1167	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
Aave_1168	ENOG4105CJR	Integral membrane protein (MviN
Aave_1169	ENOG41063JG	Transcriptional regulator
Aave_1170	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Aave_1172	ENOG4105D1Q	UPF0246 protein
Aave_1173	ENOG4105C03	ribonuclease
Aave_1174	ENOG4105EI2	Pseudouridine synthase
Aave_1177	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Aave_1178	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Aave_1179	ENOG4108UHJ	MAF-like protein
Aave_1180	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
Aave_1181	ENOG4105VGS	50s ribosomal protein l32
Aave_1182	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Aave_1183	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Aave_1184	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Aave_1185	ENOG4105CHR	reductase
Aave_1186	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Aave_1187	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Aave_1189	ENOG4105EMN	RNA polymerase sigma factor
Aave_1192	ENOG4105C0H	protease
Aave_1193	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Aave_1194	ENOG4105C3F	Signal peptidase i
Aave_1196	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Aave_1197	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Aave_1198	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
Aave_1199	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
Aave_1200	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
Aave_1201	ENOG4108NST	exported protein
Aave_1204	ENOG4105CRK	lysyL-tRNA synthetase
Aave_1212	ENOG4108VIA	integral membrane protein
Aave_1213	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Aave_1214	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Aave_1215	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Aave_1216	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Aave_1217	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Aave_1219	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Aave_1221	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Aave_1222	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Aave_1223	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Aave_1225	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Aave_1226	ENOG4105CFG	Acts as a chaperone (By similarity)
Aave_1227	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Aave_1228	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Aave_1230	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Aave_1231	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Aave_1232	ENOG4105CDU	Replicative dna helicase
Aave_1234	ENOG4108IAB	Phoh family
Aave_1235	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Aave_1237	ENOG4105CHM	Aminotransferase
Aave_1238	ENOG4105D6E	homoserine dehydrogenase
Aave_1240	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
Aave_1241	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Aave_1242	ENOG4105M00	molybdopterin converting factor, subunit 1
Aave_1243	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Aave_1248	ENOG4108ZAF	Molybdopterin
Aave_1249	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Aave_1251	ENOG4107RGH	Aldehyde dehydrogenase
Aave_1253	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
Aave_1255	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
Aave_1256	ENOG4107RZC	phospholipase d
Aave_1257	ENOG4105CHM	Aminotransferase
Aave_1258	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Aave_1259	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Aave_1261	ENOG4105CP7	Triose-phosphate isomerase
Aave_1262	ENOG4107EJC	Preprotein translocase subunit SecG
Aave_1263	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Aave_1264	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Aave_1265	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Aave_1266	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Aave_1267	ENOG4105GKE	subunit e
Aave_1268	ENOG4107QIZ	NADH dehydrogenase
Aave_1269	ENOG4108IEH	NADH dehydrogenase subunit g
Aave_1270	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Aave_1271	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Aave_1272	ENOG4105DF2	NADH dehydrogenase subunit j
Aave_1273	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Aave_1275	ENOG4105C8S	subunit m
Aave_1276	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Aave_1279	ENOG4105BZ1	(ABC) transporter
Aave_1280	ENOG4105C0Z	ABC transporter
Aave_1281	ENOG4108IV0	ABC, transporter
Aave_1284	ENOG4105C32	Amino acid ABC transporter (Permease)
Aave_1288	ENOG4107TVC	Glycosyl transferase, family 2
Aave_1292	ENOG4105VN1	Heat shock protein
Aave_1293	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Aave_1294	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Aave_1295	ENOG4105ECR	NmrA family
Aave_1296	ENOG4105KVH	Transcriptional regulator
Aave_1297	ENOG4105E5G	Alpha beta hydrolase fold
Aave_1298	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
Aave_1300	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Aave_1301	ENOG4105DQR	SNARE associated Golgi
Aave_1302	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Aave_1305	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Aave_1306	ENOG4105K8N	protein family UPF0079, ATPase
Aave_1307	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Aave_1309	ENOG4105DUM	transcriptional regulator, lysR family
Aave_1313	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Aave_1315	ENOG4105D58	Diguanylate phosphodiesterase
Aave_1316	ENOG4105D58	Diguanylate phosphodiesterase
Aave_1317	ENOG4105ED9	Protein of unknown function (DUF455)
Aave_1318	ENOG4108Z0R	Transferase
Aave_1319	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Aave_1321	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
Aave_1322	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Aave_1327	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Aave_1328	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Aave_1329	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Aave_1331	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Aave_1332	ENOG4105EZE	Cupin 4 family protein
Aave_1335	ENOG4105Q2H	domain protein
Aave_1336	ENOG4105GJM	(LipO)protein
Aave_1337	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Aave_1340	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Aave_1341	ENOG4105E4C	Lytic transglycosylase catalytic
Aave_1342	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Aave_1343	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_1344	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_1345	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
Aave_1352	ENOG4108EC8	DNA internalization-related competence protein ComEC
Aave_1357	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Aave_1359	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
Aave_1362	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Aave_1367	ENOG4105E0K	tonB-dependent siderophore receptor
Aave_1374	ENOG4108UQY	Iron-storage protein
Aave_1376	ENOG4108JU3	Alkyl hydroperoxide reductase
Aave_1377	ENOG4105HSS	phospholipase C
Aave_1381	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Aave_1382	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Aave_1384	ENOG4107QN1	sodium solute
Aave_1387	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Aave_1389	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Aave_1392	ENOG4107YNJ	LysR family Transcriptional regulator
Aave_1393	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Aave_1396	ENOG4105CHR	reductase
Aave_1397	ENOG4105CMJ	mandelate racemase muconate lactonizing
Aave_1405	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_1406	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Aave_1407	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Aave_1408	ENOG4105BZU	Histidine kinase
Aave_1409	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Aave_1410	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Aave_1411	ENOG4105DGI	Alkaline phosphatase
Aave_1412	ENOG4105BZU	Histidine kinase
Aave_1414	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Aave_1415	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Aave_1416	ENOG4108K5P	(LipO)protein
Aave_1417	ENOG4105C34	Pseudouridine synthase
Aave_1418	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Aave_1419	ENOG4105FE9	pseudouridine synthase
Aave_1420	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Aave_1421	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Aave_1422	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
Aave_1424	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Aave_1425	ENOG4105CUT	histidyl-tRNA synthetase
Aave_1428	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Aave_1429	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Aave_1430	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Aave_1431	ENOG4107QJR	hflk protein
Aave_1432	ENOG4105EPW	hflc protein
Aave_1433	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Aave_1434	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Aave_1435	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
Aave_1436	ENOG4105I08	Pseudouridine synthase
Aave_1442	ENOG4105C5F	glutamine synthetase
Aave_1444	ENOG4105CUX	Signal transduction histidine kinase
Aave_1445	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Aave_1447	ENOG4105CGK	Exodeoxyribonuclease III
Aave_1450	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
Aave_1452	ENOG4105CQB	FAD linked oxidase domain protein
Aave_1454	ENOG4107S2Z	UPF0761 membrane protein
Aave_1455	ENOG4107S11	squalene-associated FAD-dependent desaturase
Aave_1456	ENOG4105FE1	phytoene synthase
Aave_1457	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Aave_1458	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Aave_1459	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Aave_1460	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Aave_1461	ENOG4105BZS	acriflavin resistance protein
Aave_1469	ENOG4108ZF3	Phosphatase
Aave_1472	ENOG4108ZG0	Ompa motb domain protein
Aave_1482	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Aave_1484	ENOG4108VKG	metal-dependent hydrolase
Aave_1485	ENOG4105C7W	Xanthine dehydrogenase
Aave_1486	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
Aave_1488	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Aave_1490	ENOG4105BZU	Histidine kinase
Aave_1493	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Aave_1494	ENOG4105EB3	Histidine kinase
Aave_1495	ENOG4105GIJ	Glycine betaine
Aave_1496	ENOG4108HQS	Glycine betaine
Aave_1497	ENOG4108IJ7	Glycine betaine
Aave_1498	ENOG4108TEB	UPF0114 protein
Aave_1499	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Aave_1504	ENOG4105W2Z	cytochrome C, class I
Aave_1506	ENOG4105C01	Dihydroxy-acid dehydratase
Aave_1507	ENOG4108UWD	Iron-storage protein
Aave_1509	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Aave_1510	ENOG4105DRR	Transcriptional regulator, GntR family
Aave_1515	ENOG4105CEY	Amp-dependent synthetase and ligase
Aave_1519	ENOG4107YZX	Universal stress protein
Aave_1521	ENOG4105C59	p-type ATPase
Aave_1523	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
Aave_1530	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Aave_1531	ENOG4105D4P	Coproporphyrinogen iii oxidase
Aave_1533	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Aave_1534	ENOG4105BZU	Histidine kinase
Aave_1537	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Aave_1538	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Aave_1539	ENOG4108YZT	Adenosylcobinamide kinase
Aave_1541	ENOG4105EHG	Permease protein
Aave_1542	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Aave_1543	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Aave_1544	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
Aave_1545	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Aave_1548	ENOG4106N2S	
Aave_1551	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
Aave_1552	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Aave_1553	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Aave_1557	ENOG4105F2I	Transposase
Aave_1559	ENOG4105CSH	Transporter
Aave_1561	ENOG4105XYF	acetyltransferase
Aave_1562	ENOG4105CSM	endonuclease III
Aave_1563	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Aave_1564	ENOG41069P5	Protein slyX homolog
Aave_1565	ENOG4107SET	aldo keto reductase
Aave_1567	ENOG4105C1J	atp-dependent rna helicase
Aave_1571	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
Aave_1573	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
Aave_1575	ENOG4105D01	(LipO)protein
Aave_1576	ENOG4105EAC	phosphoserine phosphatase
Aave_1580	ENOG4108JA2	transcriptioN-repair coupling factor
Aave_1581	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
Aave_1582	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
Aave_1583	ENOG4105E0F	Histidine kinase
Aave_1584	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Aave_1586	ENOG4105DTD	Dehydrogenase
Aave_1588	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Aave_1595	ENOG4108Z0Z	intracellular protease Pfpi family
Aave_1597	ENOG4108NVM	synthesis repressor PhaR
Aave_1601	ENOG4105FA0	parb-like partition protein
Aave_1607	ENOG4108XTP	Transcriptional regulator
Aave_1645	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Aave_1648	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Aave_1651	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Aave_1652	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Aave_1656	ENOG4105D44	asparaginase
Aave_1657	ENOG4108JQ6	ABC transporter
Aave_1659	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Aave_1660	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Aave_1664	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Aave_1666	ENOG4105K70	DNA-binding protein
Aave_1670	ENOG4108R7K	Metal Dependent Phosphohydrolase
Aave_1691	ENOG4105CAR	Terminase, large subunit
Aave_1698	ENOG4108TFU	terminase (Small subunit)
Aave_1719	ENOG4105X5T	
Aave_1733	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Aave_1750	ENOG4108XTP	Transcriptional regulator
Aave_1796	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Aave_1798	ENOG4105C1J	atp-dependent rna helicase
Aave_1800	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Aave_1801	ENOG4105C5H	ABC transporter
Aave_1804	ENOG4105KXX	peptidase s58 dmpa
Aave_1807	ENOG4105EXG	Transcriptional regulator
Aave_1810	ENOG4107R16	Multicopper oxidase
Aave_1816	ENOG4105W1Y	Transcriptional regulator
Aave_1821	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Aave_1822	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Aave_1823	ENOG4105CE9	30S ribosomal protein S2
Aave_1824	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Aave_1825	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Aave_1826	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Aave_1828	ENOG4105KNE	Phosphatidate cytidylyltransferase
Aave_1829	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Aave_1830	ENOG4105DZP	Membrane-associated zinc metalloprotease
Aave_1831	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Aave_1833	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Aave_1834	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Aave_1835	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Aave_1836	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Aave_1837	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Aave_1839	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Aave_1841	ENOG4105CSU	acyl-Coa dehydrogenase
Aave_1842	ENOG4107RSM	transcriptional regulator
Aave_1843	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Aave_1844	ENOG4105CD8	aminopeptidase N
Aave_1846	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Aave_1847	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Aave_1848	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Aave_1849	ENOG4105CPC	Aldo Keto reductase
Aave_1850	ENOG4108Z66	YbaK ebsC protein
Aave_1851	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Aave_1853	ENOG4108WIW	Aspartyl protease
Aave_1854	ENOG4108VPT	UPF0234 protein
Aave_1856	ENOG4105CDH	Citrulline--aspartate ligase
Aave_1857	ENOG4105NBK	UPF0345 protein
Aave_1859	ENOG4105KUZ	arsenate reductase
Aave_1860	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Aave_1862	ENOG4105E96	Colicin v production protein
Aave_1863	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Aave_1864	ENOG4105C28	cystathionine
Aave_1865	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Aave_1867	ENOG4105C2C	drug resistance transporter, Bcr CflA
Aave_1868	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Aave_1872	ENOG4108RG0	uracil-dna glycosylase
Aave_1873	ENOG4105D1H	recombination factor protein RarA
Aave_1874	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_1875	ENOG4105C32	Amino acid ABC transporter (Permease)
Aave_1876	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Aave_1877	ENOG4105C0Z	ABC transporter
Aave_1878	ENOG4108IV0	ABC, transporter
Aave_1879	ENOG4105UYK	outer membrane protein a
Aave_1880	ENOG4107GRR	phosphate transport regulator
Aave_1881	ENOG4107QXV	Phosphate transporter
Aave_1884	ENOG4105K5M	30s ribosomal protein S16
Aave_1885	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Aave_1886	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Aave_1887	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Aave_1889	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Aave_1890	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Aave_1891	ENOG41090A4	Pterin carbinolamine dehydratase
Aave_1893	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
Aave_1894	ENOG4105C1J	atp-dependent rna helicase
Aave_1895	ENOG4105BZU	Histidine kinase
Aave_1896	ENOG4105C2C	drug resistance transporter, Bcr CflA
Aave_1899	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Aave_1900	ENOG4105BZU	Histidine kinase
Aave_1901	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Aave_1911	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
Aave_1916	ENOG4105C4R	Atp-dependent dna helicase
Aave_1928	ENOG4105CUV	Homoserine Kinase
Aave_1930	ENOG4105C2M	dna polymerase I
Aave_1936	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Aave_1937	ENOG4107RP9	extracellular solute-binding protein, family 3
Aave_1943	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
Aave_1945	ENOG4105CH7	arginosuccinase
Aave_1947	ENOG4108NEV	two component transcriptional regulator, LytTR family
Aave_1948	ENOG4108HRK	Histidine kinase
Aave_1949	ENOG4105CH7	arginosuccinase
Aave_1950	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Aave_1956	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_1957	ENOG4105BZ4	penicillin-binding protein
Aave_1959	ENOG4105DMF	Dehydrogenase
Aave_1960	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_1964	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Aave_1970	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Aave_1971	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
Aave_1973	ENOG4105DJ0	Poly(A) Polymerase
Aave_1974	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Aave_1981	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Aave_1982	ENOG4105C1G	acyl-Coa dehydrogenase
Aave_1983	ENOG4105ETT	transcriptional Regulator, LysR family
Aave_1987	ENOG4105C6T	cysteine synthase
Aave_1988	ENOG4105E09	nadh pyrophosphatase
Aave_1989	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
Aave_1991	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Aave_1992	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Aave_1993	ENOG4105D0M	Protease HtpX homolog
Aave_1995	ENOG4105C5H	ABC transporter
Aave_1999	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Aave_2000	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Aave_2001	ENOG4105EM2	membrane
Aave_2002	ENOG4105DSF	transport protein
Aave_2005	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
Aave_2006	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
Aave_2009	ENOG4107T8P	acyl-Coa dehydrogenase
Aave_2010	ENOG4105KHC	sulfurtransferase
Aave_2013	ENOG41086K9	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Aave_2015	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Aave_2016	ENOG4105CH5	extracellular solute-binding protein, family 7
Aave_2018	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Aave_2022	ENOG4105CG3	alpha amylase, catalytic region
Aave_2023	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
Aave_2024	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Aave_2025	ENOG4105C94	Transporter
Aave_2026	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
Aave_2027	ENOG4105E0C	molybdate abc transporter
Aave_2028	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Aave_2030	ENOG4105F4R	Transcriptional regulator mode
Aave_2032	ENOG4105D5T	phosphonate abc transporter
Aave_2035	ENOG4108VAC	response regulator
Aave_2036	ENOG4108HRK	Histidine kinase
Aave_2040	ENOG4105BZS	acriflavin resistance protein
Aave_2041	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Aave_2042	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Aave_2043	ENOG4105BZU	Histidine kinase
Aave_2047	ENOG4105CS6	Rhs element vgr protein
Aave_2049	ENOG4105CNA	YD repeat protein
Aave_2051	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Aave_2052	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Aave_2063	ENOG4105BZU	Histidine kinase
Aave_2064	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Aave_2066	ENOG4105BZ1	(ABC) transporter
Aave_2070	ENOG4105ECY	inositol monophosphatase
Aave_2073	ENOG4108IUW	ABC transporter
Aave_2076	ENOG4105D7W	serine acetyltransferase
Aave_2077	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Aave_2078	ENOG4105N42	UPF0307 protein
Aave_2079	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Aave_2080	ENOG4105CNV	Aldolase
Aave_2082	ENOG4105CTX	dehydratase
Aave_2083	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Aave_2085	ENOG41079KZ	Major Facilitator Superfamily
Aave_2086	ENOG4105D78	K07001 NTE family protein
Aave_2087	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Aave_2088	ENOG4105EJC	lysr family transcriptional regulator
Aave_2090	ENOG4108K3A	Glutathione S-transferase
Aave_2091	ENOG4105KTH	gatB Yqey
Aave_2092	ENOG4105VCC	30S ribosomal protein S21
Aave_2096	ENOG4108ZHR	arsR family transcriptional regulator
Aave_2097	ENOG4105CBX	hi0933 family
Aave_2100	ENOG41077A9	carbonic anhydrase
Aave_2102	ENOG4106R7G	Glycoside hydrolase family 5
Aave_2103	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Aave_2104	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Aave_2105	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Aave_2107	ENOG4108IFG	nitrite reductase, (NAD(P)H)
Aave_2108	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_2110	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Aave_2111	ENOG4105BZS	acriflavin resistance protein
Aave_2112	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Aave_2113	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
Aave_2114	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Aave_2116	ENOG4107QX3	carboxylase
Aave_2118	ENOG4105CBS	Chea signal transduction histidine kinase
Aave_2119	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_2121	ENOG4108VYJ	response regulator receiver protein
Aave_2124	ENOG4105EU0	Major facilitator Superfamily
Aave_2127	ENOG4105CS6	Rhs element vgr protein
Aave_2139	ENOG4105C28	cystathionine
Aave_2141	ENOG4105VFU	Rna-binding protein
Aave_2144	ENOG4105NAE	bifunctional deaminase-reductase domain protein
Aave_2145	ENOG4105D7T	ABC transporter
Aave_2147	ENOG4105I5W	Transporter
Aave_2151	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Aave_2154	ENOG4105ES9	amino acid
Aave_2160	ENOG4105CVE	Lytic murein transglycosylase
Aave_2161	ENOG4105F8C	transglutaminase domain-containing protein
Aave_2163	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Aave_2165	ENOG4108UKI	Enoyl-CoA hydratase
Aave_2167	ENOG4105EGS	Mechanosensitive ion channel
Aave_2168	ENOG4105BZJ	Electron transfer flavoprotein
Aave_2169	ENOG4105C10	Electron transfer flavoprotein
Aave_2170	ENOG4105CSU	acyl-Coa dehydrogenase
Aave_2179	ENOG4105CH2	amidohydrolase
Aave_2180	ENOG4108RYR	transcriptional regulator AsnC family
Aave_2181	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Aave_2182	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
Aave_2186	ENOG4105CJP	fad dependent oxidoreductase
Aave_2189	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Aave_2191	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Aave_2193	ENOG4105DIJ	Phosphoethanolamine transferase
Aave_2194	ENOG4105C4W	S-formylglutathione hydrolase
Aave_2195	ENOG4107QPD	alcohol dehydrogenase
Aave_2197	ENOG41068WN	
Aave_2199	ENOG4105BZN	citrate synthase
Aave_2200	ENOG41060IS	Flavinator of succinate dehydrogenase
Aave_2201	ENOG4105E33	succinate dehydrogenase
Aave_2205	ENOG4105FDP	GntR family transcriptional regulator
Aave_2206	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Aave_2207	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
Aave_2210	ENOG4107QIJ	Aconitate hydratase 2
Aave_2214	ENOG4105CFP	Peptidase U32
Aave_2215	ENOG4108W5M	transcriptional regulator
Aave_2217	ENOG4108UYB	regulatoR
Aave_2218	ENOG4105DS4	PAS PAC sensor Signal transduction histidine kinase
Aave_2220	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
Aave_2221	ENOG4105CCU	oxidase (Subunit III)
Aave_2222	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Aave_2223	ENOG4105E2S	oxidase) subunit II
Aave_2224	ENOG4105CSH	Transporter
Aave_2226	ENOG4105M8F	Biopolymer transport protein exbD tolR
Aave_2227	ENOG4105E02	MotA TolQ exbB proton channel
Aave_2228	ENOG4107YD3	Thioesterase
Aave_2229	ENOG4105CHM	Aminotransferase
Aave_2230	ENOG4107YIM	Involved in the transcription termination process (By similarity)
Aave_2231	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Aave_2232	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Aave_2234	ENOG410811Q	Ferredoxin
Aave_2236	ENOG4105BZU	Histidine kinase
Aave_2238	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Aave_2239	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Aave_2241	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_2243	ENOG4105ME7	Membrane
Aave_2244	ENOG4105CXK	mandelate racemase muconate lactonizing
Aave_2245	ENOG4108RTU	Aldolase
Aave_2246	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
Aave_2249	ENOG41062B0	ABC transporter, permease
Aave_2250	ENOG4107R9N	ABC transporter
Aave_2251	ENOG4105C2J	ABC transporter
Aave_2252	ENOG4107RNG	ABC transporter
Aave_2254	ENOG4105DFW	ABC transporter
Aave_2255	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
Aave_2259	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
Aave_2262	ENOG4105D9M	gamma-glutamylcysteine synthetase
Aave_2264	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Aave_2266	ENOG4108NIW	Leucine export protein LeuE
Aave_2270	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
Aave_2271	ENOG4108Z9W	Outer membrane porin
Aave_2274	ENOG4105EQ0	Major Facilitator superfamily
Aave_2276	ENOG4108Z4X	TRANSCRIPTIONal
Aave_2277	ENOG4108302	MgtC SapB transporter
Aave_2278	ENOG4105DR9	pseudouridine synthase
Aave_2283	ENOG4108JP0	extracellular solute-binding protein family 1
Aave_2284	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_2287	ENOG4108R99	pseudouridine synthase
Aave_2290	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Aave_2297	ENOG4108RZE	Tetr family transcriptional regulator
Aave_2300	ENOG4105CX6	glutaminyL-tRNA synthetase
Aave_2302	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Aave_2304	ENOG4108YZN	class I peptide chain release factor
Aave_2305	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
Aave_2309	ENOG4108YXU	transcriptional regulator AsnC family
Aave_2312	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Aave_2314	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
Aave_2315	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
Aave_2320	ENOG4105C8N	cysteinyl-tRNA synthetase
Aave_2323	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Aave_2324	ENOG4105CFH	Aspartokinase
Aave_2336	ENOG4105W7J	DNA binding
Aave_2395	ENOG4105MQ5	zona occludens toxin
Aave_2417	ENOG4105BZU	Histidine kinase
Aave_2419	ENOG4105VEJ	Heat shock protein
Aave_2428	ENOG4105BZC	d-serine deaminase
Aave_2430	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Aave_2431	ENOG4105FC8	fad dependent oxidoreductase
Aave_2434	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Aave_2436	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_2437	ENOG4105CCT	upf0313 protein
Aave_2439	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
Aave_2440	ENOG4105CGF	Aromatic amino acid aminotransferase
Aave_2441	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Aave_2442	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Aave_2443	ENOG4105C3J	Cysteine desulfurase
Aave_2444	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
Aave_2446	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
Aave_2447	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
Aave_2448	ENOG4108ZIT	Ferredoxin, 2FE-2S
Aave_2449	ENOG4108JDX	DNA polymerase iii, epsilon subunit
Aave_2450	ENOG41067B5	Histone deacetylase superfamily protein
Aave_2451	ENOG4105D5U	fad dependent oxidoreductase
Aave_2455	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Aave_2456	ENOG4105E66	phosphoriboisomerase A
Aave_2458	ENOG4105DGW	oligopeptidase A
Aave_2459	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Aave_2460	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Aave_2461	ENOG4105BZU	Histidine kinase
Aave_2462	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
Aave_2463	ENOG4107QSN	dihydrolipoamide acetyltransferase
Aave_2464	ENOG4107QN2	dihydrolipoyl dehydrogenase
Aave_2468	ENOG4105DR4	Methyltransferase
Aave_2469	ENOG4105BZ4	penicillin-binding protein
Aave_2470	ENOG4105F87	Dehydratase
Aave_2471	ENOG4107TPY	serine threonine protein kinase
Aave_2475	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Aave_2477	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
Aave_2478	ENOG4105CHU	acetyl-coa acetyltransferase
Aave_2479	ENOG4105CHR	reductase
Aave_2480	ENOG4105C5H	ABC transporter
Aave_2481	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
Aave_2482	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Aave_2483	ENOG4105CZX	twitching motility protein
Aave_2484	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Aave_2486	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_2487	ENOG4108R3D	Electron transport complex
Aave_2490	ENOG4105BZU	Histidine kinase
Aave_2491	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Aave_2493	ENOG4105MP0	transposase
Aave_2494	ENOG4105F2I	Transposase
Aave_2496	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_2507	ENOG4105BZU	Histidine kinase
Aave_2508	ENOG4105BZU	Histidine kinase
Aave_2509	ENOG4105DRR	Transcriptional regulator, GntR family
Aave_2512	ENOG4105DJT	lAO AO transport system ATPase
Aave_2513	ENOG4107QX3	carboxylase
Aave_2515	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Aave_2518	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Aave_2519	ENOG4105DQE	DNA ligase
Aave_2520	ENOG4105FDF	Could be involved in DNA repair (By similarity)
Aave_2525	ENOG4105BZU	Histidine kinase
Aave_2528	ENOG4105BZS	acriflavin resistance protein
Aave_2529	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Aave_2533	ENOG4105CR8	Transcriptional regulator
Aave_2534	ENOG4105EQ0	Major Facilitator superfamily
Aave_2536	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Aave_2537	ENOG4108UMI	ABC transporter, permease
Aave_2538	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_2539	ENOG4105D01	(LipO)protein
Aave_2541	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Aave_2542	ENOG4105EXG	Transcriptional regulator
Aave_2545	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
Aave_2546	ENOG4108I5D	sulfate abc transporter
Aave_2547	ENOG4105ECW	sulfate abc transporter
Aave_2548	ENOG4108IJ6	ABC transporter
Aave_2549	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
Aave_2550	ENOG4105C72	UPF0176 protein
Aave_2551	ENOG4105ETT	transcriptional Regulator, LysR family
Aave_2553	ENOG4108EKC	n-acetylglutamate synthase
Aave_2554	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Aave_2556	ENOG4105CQ7	ATP-dependent helicase
Aave_2558	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Aave_2559	ENOG4105HDK	L-asparaginase
Aave_2561	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Aave_2562	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Aave_2563	ENOG4105W49	UPF0434 protein
Aave_2564	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Aave_2565	ENOG4108ZZF	transport protein (ExbD)
Aave_2567	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Aave_2568	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Aave_2573	ENOG4105EXG	Transcriptional regulator
Aave_2574	ENOG4108K3A	Glutathione S-transferase
Aave_2575	ENOG4105VSH	4-oxalocrotonate tautomerase
Aave_2578	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Aave_2579	ENOG4108Z4X	TRANSCRIPTIONal
Aave_2587	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
Aave_2590	ENOG4105E9Z	Nad-dependent epimerase dehydratase
Aave_2592	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Aave_2594	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Aave_2595	ENOG4105CTX	dehydratase
Aave_2598	ENOG4105CHB	tonB-dependent Receptor
Aave_2599	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Aave_2600	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Aave_2602	ENOG4105C1G	acyl-Coa dehydrogenase
Aave_2604	ENOG4105C26	Dehydrogenase
Aave_2608	ENOG4105C85	amino acid
Aave_2611	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Aave_2612	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Aave_2615	ENOG4105HBR	Rna-binding protein
Aave_2616	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Aave_2617	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Aave_2618	ENOG4105EEI	dihydropteroate synthase
Aave_2619	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Aave_2620	ENOG4105BZU	Histidine kinase
Aave_2622	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Aave_2625	ENOG4105C9X	ppx gppa phosphatase
Aave_2626	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
Aave_2627	ENOG4105C8U	phosphate abc transporter
Aave_2628	ENOG4105E2Z	phosphate ABC transporter (Permease
Aave_2629	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Aave_2630	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Aave_2631	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Aave_2632	ENOG4105BZU	Histidine kinase
Aave_2633	ENOG4107QI1	Mate efflux family protein
Aave_2635	ENOG4105NRA	50s ribosomal protein l31 type b
Aave_2636	ENOG4107RH8	nuclease SbcCD subunit D
Aave_2637	ENOG4105EYH	Exonuclease
Aave_2638	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Aave_2639	ENOG4105K63	Thioredoxin
Aave_2641	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Aave_2642	ENOG4105CBX	hi0933 family
Aave_2643	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_2644	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Aave_2645	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Aave_2646	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Aave_2650	ENOG4105E9H	Lytic Murein transglycosylase
Aave_2651	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Aave_2652	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Aave_2653	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Aave_2656	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Aave_2658	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Aave_2659	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Aave_2662	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Aave_2664	ENOG4105C26	Dehydrogenase
Aave_2669	ENOG4105F0N	pyrophosphate phospho-hydrolase
Aave_2672	ENOG4105C0B	DNA polymerase III (alpha subunit)
Aave_2673	ENOG41066T0	asmA family
Aave_2674	ENOG4105D3G	Pseudouridine synthase
Aave_2676	ENOG4107U53	septum site-determining protein minD
Aave_2702	ENOG4108C33	Resolvase
Aave_2706	ENOG4106RHG	Yeca family
Aave_2716	ENOG4105CZX	twitching motility protein
Aave_2719	ENOG4107QHF	type ii secretion system protein e
Aave_2722	ENOG4107QHF	type ii secretion system protein e
Aave_2727	ENOG4105E4C	Lytic transglycosylase catalytic
Aave_2730	ENOG4105T95	Thiol disulfide interChange protein
Aave_2731	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Aave_2732	ENOG4105C0B	DNA polymerase III (alpha subunit)
Aave_2735	ENOG4105CS6	Rhs element vgr protein
Aave_2740	ENOG4105CNA	YD repeat protein
Aave_2749	ENOG4105UKP	Protein of unknown function (DUF1778)
Aave_2779	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Aave_2781	ENOG4108UZX	fmn reductase
Aave_2782	ENOG4105DZ2	Transcriptional regulator
Aave_2790	ENOG4105CHR	reductase
Aave_2791	ENOG4108UYE	Lactoylglutathione lyase
Aave_2792	ENOG4108UHU	Aldolase
Aave_2793	ENOG4105C01	Dihydroxy-acid dehydratase
Aave_2794	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Aave_2795	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Aave_2796	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
Aave_2797	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
Aave_2798	ENOG4105K2J	Transcriptional regulator
Aave_2803	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
Aave_2806	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Aave_2807	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Aave_2812	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Aave_2814	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Aave_2815	ENOG4105YA8	Transcriptional regulator
Aave_2816	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Aave_2818	ENOG4105DFG	type I secretion outer membrane protein
Aave_2819	ENOG4105CD5	CoA-binding domain protein
Aave_2820	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Aave_2822	ENOG4107QKV	phosphomannomutase
Aave_2826	ENOG4105BZU	Histidine kinase
Aave_2827	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Aave_2829	ENOG4105D8V	Glucose sorbosone dehydrogenase
Aave_2830	ENOG4105K4H	Nlp p60 protein
Aave_2833	ENOG4105C0D	helicase
Aave_2838	ENOG4105CNA	YD repeat protein
Aave_2840	ENOG4105CS6	Rhs element vgr protein
Aave_2841	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Aave_2843	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Aave_2845	ENOG4105KK4	UPF0060 membrane protein
Aave_2846	ENOG4105BZU	Histidine kinase
Aave_2847	ENOG4107R5R	arsenical pump membrane protein
Aave_2848	ENOG4105BZ1	(ABC) transporter
Aave_2852	ENOG4108XDN	Transcriptional regulator
Aave_2853	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Aave_2854	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Aave_2855	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Aave_2856	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Aave_2857	ENOG4105VJV	50s ribosomal protein L35
Aave_2858	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Aave_2859	ENOG4105C22	threonyL-tRNA synthetase
Aave_2860	ENOG4108I9X	Isocitrate lyase
Aave_2863	ENOG4105F7P	transcriptional regulator AsnC family
Aave_2864	ENOG4108Q5Y	Membrane
Aave_2871	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
Aave_2873	ENOG4105CHR	reductase
Aave_2877	ENOG4105CSU	acyl-Coa dehydrogenase
Aave_2878	ENOG4108VUY	thioesterase Superfamily protein
Aave_2879	ENOG4105CHU	acetyl-coa acetyltransferase
Aave_2880	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Aave_2925	ENOG4105BZU	Histidine kinase
Aave_2926	ENOG4106TD9	Diguanylate cyclase
Aave_2930	ENOG4108IV0	ABC, transporter
Aave_2931	ENOG4105C0Z	ABC transporter
Aave_2933	ENOG4105C32	Amino acid ABC transporter (Permease)
Aave_2936	ENOG4105MP0	transposase
Aave_2940	ENOG4106RHG	Yeca family
Aave_2944	ENOG4108C33	Resolvase
Aave_2946	ENOG4105CEY	Amp-dependent synthetase and ligase
Aave_2947	ENOG4105CNG	UPF0061 protein
Aave_2948	ENOG4105E0X	reductase
Aave_2949	ENOG4107835	probably involved in intracellular septation (By similarity)
Aave_2951	ENOG4107TF3	peptidylprolyl cis-trans isomerase
Aave_2954	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Aave_2955	ENOG4105DJ4	phosphatidylserine decarboxylase
Aave_2958	ENOG4107AQZ	Membrane
Aave_2961	ENOG4105CI2	imidazolone-5-propionate hydrolase
Aave_2964	ENOG4105CGP	Urocanate hydratase
Aave_2965	ENOG4105C84	Histidine ammonia-lyase
Aave_2966	ENOG4105CZE	histidine utilization repressor
Aave_2968	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Aave_2970	ENOG4107MMM	Anti-sigma-factor antagonist
Aave_2971	ENOG4105FUA	antagonist
Aave_2972	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
Aave_2974	ENOG4105BZU	Histidine kinase
Aave_2975	ENOG4105BZU	Histidine kinase
Aave_2978	ENOG4105BZU	Histidine kinase
Aave_2980	ENOG4105BZU	Histidine kinase
Aave_2982	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Aave_2986	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Aave_2987	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
Aave_2988	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Aave_2991	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
Aave_2992	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Aave_2993	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Aave_2995	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Aave_2996	ENOG4108IJ8	ABC transporter
Aave_2999	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
Aave_3000	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Aave_3001	ENOG4105BZU	Histidine kinase
Aave_3005	ENOG4106BE1	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers (By similarity)
Aave_3013	ENOG4105DHQ	Histidine kinase
Aave_3016	ENOG4105CPC	Aldo Keto reductase
Aave_3017	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Aave_3018	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Aave_3019	ENOG4108I0Y	(ABC) transporter
Aave_3020	ENOG4108UJV	acyl-CoA thioesterase i
Aave_3021	ENOG4105C28	cystathionine
Aave_3024	ENOG4105BZU	Histidine kinase
Aave_3025	ENOG4107R21	site-determining protein
Aave_3026	ENOG4105C72	UPF0176 protein
Aave_3027	ENOG4105EUB	pirin domain protein
Aave_3029	ENOG4105C2I	pirin domain protein
Aave_3030	ENOG4105CWB	LysR family transcriptional Regulator
Aave_3031	ENOG4105CVN	desaturase
Aave_3032	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
Aave_3033	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Aave_3034	ENOG4105BZU	Histidine kinase
Aave_3035	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Aave_3039	ENOG4107R11	Transcriptional regulator
Aave_3041	ENOG4105E2Y	ABC, transporter
Aave_3042	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Aave_3044	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
Aave_3045	ENOG4105GVF	(ABC) transporter
Aave_3046	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
Aave_3047	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
Aave_3048	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
Aave_3052	ENOG4107TSN	permease
Aave_3055	ENOG4105C11	sulfate adenylyltransferase), subunit 2
Aave_3056	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
Aave_3057	ENOG4108Z4U	Ferredoxin
Aave_3058	ENOG4105CAY	ferredoxin--nadp reductase
Aave_3066	ENOG4105D9P	serine threonine protein kinase
Aave_3070	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Aave_3071	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Aave_3073	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Aave_3074	ENOG4108UKI	Enoyl-CoA hydratase
Aave_3077	ENOG4105C1G	acyl-Coa dehydrogenase
Aave_3081	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Aave_3082	ENOG4108Z6B	deaminase
Aave_3086	ENOG4105CFP	Peptidase U32
Aave_3088	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Aave_3090	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
Aave_3091	ENOG41067HS	methyltransferase
Aave_3093	ENOG4105BZU	Histidine kinase
Aave_3095	ENOG4105CKW	Inner membrane protein yedI
Aave_3096	ENOG4105BZU	Histidine kinase
Aave_3099	ENOG4108ETH	Formylglycinamide ribotide synthetase
Aave_3100	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Aave_3101	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Aave_3102	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Aave_3103	ENOG4105WD1	Membrane
Aave_3104	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
Aave_3105	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
Aave_3106	ENOG41069M3	Transcriptional regulator
Aave_3107	ENOG41061WM	D-Alanyl-D-Alanine
Aave_3108	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Aave_3109	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Aave_3110	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Aave_3111	ENOG4108ZP8	Acetolactate synthase small subunit
Aave_3112	ENOG4105C7K	acetolactate synthase
Aave_3113	ENOG4105JVQ	RNA Polymerase
Aave_3117	ENOG41080IJ	Diacylglycerol kinase
Aave_3118	ENOG4108URH	decarboxylase
Aave_3119	ENOG4108YZA	Nitrogen regulatory protein pii
Aave_3122	ENOG4105EMY	transcriptional regulator
Aave_3125	ENOG4108V3W	Chemotaxis protein, CheW
Aave_3130	ENOG4105CEP	NADH dehydrogenase
Aave_3132	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
Aave_3137	ENOG4105CH6	catalase
Aave_3138	ENOG4108R85	Short chain dehydrogenase
Aave_3139	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Aave_3142	ENOG4105C7J	ABC transporter, permease
Aave_3144	ENOG4105EW9	transcriptional regulator AsnC family
Aave_3145	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Aave_3147	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Aave_3148	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Aave_3150	ENOG4105D3G	Pseudouridine synthase
Aave_3151	ENOG410904N	short-chain dehydrogenase reductase
Aave_3154	ENOG41081QV	Universal stress protein
Aave_3157	ENOG4105CEY	Amp-dependent synthetase and ligase
Aave_3162	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Aave_3166	ENOG4107R11	Transcriptional regulator
Aave_3167	ENOG4105CHM	Aminotransferase
Aave_3170	ENOG4108IV0	ABC, transporter
Aave_3171	ENOG4105C0Z	ABC transporter
Aave_3173	ENOG4105C32	Amino acid ABC transporter (Permease)
Aave_3174	ENOG4105CAD	extracellular ligand-binding receptor
Aave_3176	ENOG4105C1G	acyl-Coa dehydrogenase
Aave_3177	ENOG4108UKI	Enoyl-CoA hydratase
Aave_3179	ENOG4105DTD	Dehydrogenase
Aave_3182	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
Aave_3183	ENOG4105BZU	Histidine kinase
Aave_3185	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
Aave_3186	ENOG4105C4R	Atp-dependent dna helicase
Aave_3196	ENOG4105C03	ribonuclease
Aave_3197	ENOG4108Z03	MAF-like protein
Aave_3199	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Aave_3200	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
Aave_3201	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
Aave_3202	ENOG4105C12	Phosphoribosylglycinamide synthetase
Aave_3203	ENOG4105CDY	transcriptional regulatory protein
Aave_3204	ENOG4105D7A	ATP-binding protein
Aave_3209	ENOG4105CQB	FAD linked oxidase domain protein
Aave_3210	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
Aave_3212	ENOG4105KHC	sulfurtransferase
Aave_3215	ENOG4105CYM	Glutathione S-transferase
Aave_3218	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Aave_3219	ENOG4108YYQ	gCN5-related N-acetyltransferase
Aave_3221	ENOG4105DZC	cytosine deaminase
Aave_3228	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Aave_3230	ENOG4105C26	Dehydrogenase
Aave_3234	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
Aave_3235	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Aave_3236	ENOG4105CJB	Exodeoxyribonuclease I
Aave_3237	ENOG4105CVE	Lytic murein transglycosylase
Aave_3238	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Aave_3239	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Aave_3240	ENOG4105C0B	DNA polymerase III (alpha subunit)
Aave_3242	ENOG4105DVT	helicase
Aave_3245	ENOG4105D6Z	AFG1 family ATPase
Aave_3246	ENOG4107QN2	dihydrolipoyl dehydrogenase
Aave_3247	ENOG4105C7S	Dehydrogenase
Aave_3248	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Aave_3249	ENOG4105IPI	Membrane
Aave_3250	ENOG4105BZU	Histidine kinase
Aave_3251	ENOG4108JQ5	ABC transporter
Aave_3252	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
Aave_3253	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
Aave_3254	ENOG4105E43	Extracellular solute-binding protein, family 5
Aave_3255	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Aave_3257	ENOG4105CXN	decarboxylase
Aave_3274	ENOG4105ETX	regulatoR
Aave_3277	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Aave_3278	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Aave_3279	ENOG4105UYK	outer membrane protein a
Aave_3280	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Aave_3281	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Aave_3282	ENOG4105CQC	Prephenate dehydratase
Aave_3284	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Aave_3285	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Aave_3286	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Aave_3288	ENOG4105CFV	Tetratricopeptide repeat protein
Aave_3289	ENOG4105D65	subunit l
Aave_3290	ENOG4108ZE9	Monovalent cation H antiporter subunit C
Aave_3291	ENOG4107R4Z	monovalent cation h antiporter subunit d
Aave_3293	ENOG4105W4C	monovalent cation H antiporter subunit F
Aave_3299	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Aave_3300	ENOG4107Z6W	Protein CrcB homolog
Aave_3304	ENOG4107QSV	RmuC domain protein
Aave_3305	ENOG4105C5I	Dehydrogenase
Aave_3306	ENOG4107RH7	Nicotinate phosphoribosyltransferase
Aave_3307	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Aave_3309	ENOG4108WFY	phasin family
Aave_3313	ENOG4105SG9	biopolymer transport protein, ExbD
Aave_3315	ENOG4108ZJF	Glcg protein
Aave_3316	ENOG4108MN8	Membrane
Aave_3318	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Aave_3320	ENOG4105EW9	transcriptional regulator AsnC family
Aave_3321	ENOG4105C26	Dehydrogenase
Aave_3323	ENOG4105EHG	Permease protein
Aave_3325	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Aave_3326	ENOG4108ESX	Receptor
Aave_3328	ENOG4108K3A	Glutathione S-transferase
Aave_3332	ENOG4107VIJ	nudix hydrolase
Aave_3333	ENOG4105VEQ	Cold shock protein
Aave_3336	ENOG4105CAY	ferredoxin--nadp reductase
Aave_3337	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
Aave_3345	ENOG4105CNA	YD repeat protein
Aave_3347	ENOG4105CS6	Rhs element vgr protein
Aave_3349	ENOG4105CHR	reductase
Aave_3351	ENOG4105EQ2	LysR family Transcriptional regulator
Aave_3357	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Aave_3358	ENOG4107XZC	Restriction modification system DNA (Specificity
Aave_3359	ENOG4105CVR	type I restriction-modification system
Aave_3366	ENOG4105DFP	Integrase
Aave_3367	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Aave_3370	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Aave_3372	ENOG4105VDB	UPF0125 protein
Aave_3373	ENOG4108Z1B	Cyclase dehydrase
Aave_3374	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Aave_3378	ENOG4105E39	Enoyl-CoA hydratase
Aave_3379	ENOG4105EE5	Membrane protein terC
Aave_3381	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Aave_3382	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Aave_3383	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Aave_3384	ENOG4105CHV	Transcription elongation factor NusA
Aave_3385	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Aave_3387	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
Aave_3400	ENOG4105F84	Ornithine cyclodeaminase
Aave_3403	ENOG4105CUZ	uba thif-type nad fad binding protein
Aave_3405	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Aave_3406	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
Aave_3407	ENOG4105BZ1	(ABC) transporter
Aave_3409	ENOG4105F8V	Hydrolase, tatD family
Aave_3412	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Aave_3413	ENOG4105HHA	aminodeoxychorismate lyase
Aave_3414	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
Aave_3417	ENOG4105IKQ	hydratase
Aave_3418	ENOG4108JB8	alcohol dehydrogenase
Aave_3421	ENOG4105BZM	domain protein
Aave_3425	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
Aave_3426	ENOG4105CNU	cell division protein FtsK
Aave_3427	ENOG4105C3M	thioredoxin reductase
Aave_3428	ENOG4105KDC	50s ribosomal protein l28
Aave_3429	ENOG4105W0E	50S ribosomal protein L33
Aave_3430	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Aave_3434	ENOG4108J20	pectate lyase
Aave_3437	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Aave_3438	ENOG4108YXG	UPF0502 protein
Aave_3439	ENOG4105X7H	acyl-CoA dehydrogenase
Aave_3443	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Aave_3444	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_3445	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Aave_3447	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Aave_3449	ENOG4105DTN	riboflavin biosynthesis protein ribF
Aave_3451	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Aave_3453	ENOG4105ETE	Transcriptional regulator (LacI family
Aave_3455	ENOG4105E0C	molybdate abc transporter
Aave_3456	ENOG4105D38	putrescine abc transporter
Aave_3457	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Aave_3458	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
Aave_3460	ENOG4105F2I	Transposase
Aave_3461	ENOG4105EAM	Na Pi-cotransporter
Aave_3463	ENOG4107NQ8	LysR family Transcriptional regulator
Aave_3465	ENOG4105DHU	Bile acid
Aave_3468	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Aave_3469	ENOG4108IPJ	Membrane
Aave_3478	ENOG4105CNA	YD repeat protein
Aave_3481	ENOG4105CNA	YD repeat protein
Aave_3486	ENOG4105CS6	Rhs element vgr protein
Aave_3487	ENOG4105BZU	Histidine kinase
Aave_3490	ENOG4107TE5	Lipid kinase
Aave_3492	ENOG4105F27	Major Facilitator
Aave_3496	ENOG4108IV0	ABC, transporter
Aave_3497	ENOG4105C0Z	ABC transporter
Aave_3499	ENOG4105C32	Amino acid ABC transporter (Permease)
Aave_3500	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
Aave_3501	ENOG4105CK2	sodium dicarboxylate symporter
Aave_3502	ENOG41090FM	Phosphatase
Aave_3507	ENOG4105CPW	cytochrome b561
Aave_3510	ENOG4108JIK	carboxylase
Aave_3511	ENOG4105P4J	Allophanate hydrolase, subunit 1
Aave_3512	ENOG4105CFM	UPF0317 protein
Aave_3513	ENOG4105E7W	lamb ycsf family protein
Aave_3514	ENOG4107RGD	Major Facilitator superfamily
Aave_3517	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
Aave_3518	ENOG4106F60	Histidine kinase
Aave_3524	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Aave_3525	ENOG4105BZU	Histidine kinase
Aave_3526	ENOG4108YZ9	Urea amidohydrolase subunit gamma
Aave_3528	ENOG4105KI2	Urea amidohydrolase subunit beta
Aave_3529	ENOG4105CQM	Urea amidohydrolase subunit alpha
Aave_3531	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
Aave_3532	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
Aave_3533	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
Aave_3540	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
Aave_3545	ENOG4105BZU	Histidine kinase
Aave_3546	ENOG4105BZU	Histidine kinase
Aave_3548	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Aave_3549	ENOG4106855	Competence protein
Aave_3550	ENOG4106855	Competence protein
Aave_3555	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Aave_3564	ENOG4105BZU	Histidine kinase
Aave_3565	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Aave_3570	ENOG4105K6V	RNA polymerase
Aave_3573	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Aave_3574	ENOG4105EMU	Dehydrogenase
Aave_3577	ENOG4105CSA	Coproporphyrinogen iii oxidase
Aave_3578	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Aave_3582	ENOG4105DSJ	YicC domain protein
Aave_3583	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Aave_3584	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Aave_3585	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Aave_3586	ENOG4108RRZ	Transcription elongation factor GreB
Aave_3591	ENOG4105WH1	Two component transcriptional regulator luxr family
Aave_3593	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Aave_3601	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Aave_3602	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Aave_3603	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Aave_3604	ENOG4105CEN	a g-specific adenine glycosylase
Aave_3606	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Aave_3609	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Aave_3610	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Aave_3611	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Aave_3612	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Aave_3613	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
Aave_3615	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Aave_3616	ENOG4105C3U	ABC transporter
Aave_3617	ENOG4108JQ7	(ABC) transporter
Aave_3619	ENOG4105DEF	Extracellular solute-binding protein, family 5
Aave_3625	ENOG4105DIQ	Transcriptional regulator
Aave_3631	ENOG4105EUJ	GTP cyclohydrolase i
Aave_3632	ENOG4105DZQ	phospholipase D Transphosphatidylase
Aave_3634	ENOG4108VYJ	response regulator receiver protein
Aave_3635	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Aave_3637	ENOG4105C9M	aspartyl-trna synthetase
Aave_3641	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
Aave_3644	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Aave_3646	ENOG4105BZU	Histidine kinase
Aave_3649	ENOG4108JQ1	Dehydrogenase
Aave_3650	ENOG4105BZ7	extracellular solute-binding protein family 1
Aave_3651	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
Aave_3653	ENOG4108IJ9	(ABC) transporter
Aave_3655	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
Aave_3656	ENOG4105EGS	Mechanosensitive ion channel
Aave_3663	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Aave_3664	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Aave_3667	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Aave_3668	ENOG4105C37	(CBS) domain
Aave_3669	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
Aave_3670	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Aave_3671	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Aave_3672	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Aave_3673	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Aave_3674	ENOG4105K46	50S ribosomal protein l27
Aave_3675	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Aave_3676	ENOG4105EAH	synthase
Aave_3677	ENOG4105CH2	amidohydrolase
Aave_3680	ENOG4107QHF	type ii secretion system protein e
Aave_3682	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
Aave_3683	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Aave_3684	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
Aave_3685	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
Aave_3686	ENOG4105M6F	mutator MutT protein
Aave_3688	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Aave_3689	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Aave_3690	ENOG4105DR5	peptidase
Aave_3692	ENOG4105KB2	stringent starvation protein b
Aave_3693	ENOG4107MKT	Stringent starvation protein a
Aave_3694	ENOG4105EIX	cytochrome c1
Aave_3695	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Aave_3696	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Aave_3697	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Aave_3698	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Aave_3699	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Aave_3700	ENOG4105D60	lipoprotein releasing system transmembrane protein
Aave_3702	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Aave_3704	ENOG4105X1Z	Methyltransferase type 12
Aave_3706	ENOG4106UW1	Major Facilitator superfamily
Aave_3707	ENOG4105DB7	PHP domain protein
Aave_3708	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
Aave_3710	ENOG4108Z4T	Peptidase M50
Aave_3711	ENOG4105C31	Tryptophanyl-tRNA synthetase
Aave_3712	ENOG4105CNA	YD repeat protein
Aave_3717	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Aave_3723	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
Aave_3724	ENOG4105IBP	Cyclic peptide transporter
Aave_3726	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Aave_3728	ENOG4105E0K	tonB-dependent siderophore receptor
Aave_3729	ENOG4105CEY	Amp-dependent synthetase and ligase
Aave_3739	ENOG4105CFG	Acts as a chaperone (By similarity)
Aave_3751	ENOG4105CNA	YD repeat protein
Aave_3752	ENOG4105CS6	Rhs element vgr protein
Aave_3753	ENOG4105C1V	Peptidase, M16
Aave_3754	ENOG4105DRP	amino acid AbC transporter
Aave_3755	ENOG4105DRP	amino acid AbC transporter
Aave_3756	ENOG4106PMH	Extracellular solute-binding protein family 3
Aave_3759	ENOG4105C01	Dihydroxy-acid dehydratase
Aave_3762	ENOG4105BZU	Histidine kinase
Aave_3767	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Aave_3768	ENOG4105C7B	Threonine dehydratase
Aave_3771	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Aave_3772	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
Aave_3773	ENOG4105W5Q	DNA repair protein (RadC
Aave_3777	ENOG4105C98	muts2 protein
Aave_3778	ENOG4105E0F	Histidine kinase
Aave_3779	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Aave_3782	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
Aave_3783	ENOG4105CS6	Rhs element vgr protein
Aave_3788	ENOG4105CNA	YD repeat protein
Aave_3794	ENOG4105CNA	YD repeat protein
Aave_3800	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Aave_3803	ENOG4107QI1	Mate efflux family protein
Aave_3804	ENOG4105CEY	Amp-dependent synthetase and ligase
Aave_3813	ENOG4105DRR	Transcriptional regulator, GntR family
Aave_3815	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Aave_3816	ENOG41083Z3	extracellular ligand-binding receptor
Aave_3817	ENOG4108IV0	ABC, transporter
Aave_3818	ENOG4105C0Z	ABC transporter
Aave_3819	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Aave_3820	ENOG4105C32	Amino acid ABC transporter (Permease)
Aave_3821	ENOG4105DV0	amidase (EC 3.5.1.4
Aave_3822	ENOG4105C26	Dehydrogenase
Aave_3823	ENOG4105EXG	Transcriptional regulator
Aave_3824	ENOG4105CV6	ABC transporter, permease
Aave_3826	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Aave_3827	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
Aave_3828	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_3829	ENOG4105FCD	Major Facilitator
Aave_3833	ENOG4105C7K	acetolactate synthase
Aave_3834	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Aave_3840	ENOG4108IYU	L-aspartate oxidase
Aave_3842	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
Aave_3843	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Aave_3844	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Aave_3845	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Aave_3850	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Aave_3851	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Aave_3852	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Aave_3853	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Aave_3854	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Aave_3855	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
Aave_3857	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Aave_3858	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Aave_3859	ENOG4105CN1	protease
Aave_3860	ENOG4105D06	uba thif-type nad fad binding protein
Aave_3862	ENOG4105WH1	Two component transcriptional regulator luxr family
Aave_3863	ENOG4105BZU	Histidine kinase
Aave_3869	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Aave_3870	ENOG4106H78	methyltransferase
Aave_3875	ENOG4105ERH	Fumarylacetoacetate hydrolase
Aave_3876	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
Aave_3877	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
Aave_3880	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_3881	ENOG4105ECQ	AraC Family Transcriptional Regulator
Aave_3884	ENOG4107QJQ	Mate efflux family protein
Aave_3888	ENOG4105CHM	Aminotransferase
Aave_3889	ENOG4107RCV	ABC transporter, permease
Aave_3890	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Aave_3892	ENOG4105DND	Transcriptional regulator
Aave_3894	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Aave_3899	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Aave_3900	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
Aave_3903	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
Aave_3907	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
Aave_3908	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Aave_3909	ENOG41081UC	Inherit from COG: Competence protein
Aave_3910	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Aave_3911	ENOG4105CC0	LysR family Transcriptional regulator
Aave_3914	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
Aave_3915	ENOG410829K	Lysine exporter protein (Lyse ygga)
Aave_3916	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Aave_3917	ENOG4105E0K	tonB-dependent siderophore receptor
Aave_3921	ENOG4105CPW	cytochrome b561
Aave_3922	ENOG4108VHT	MarR family transcriptional regulator
Aave_3923	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_3924	ENOG41079KZ	Major Facilitator Superfamily
Aave_3925	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
Aave_3926	ENOG4108XHQ	(2Fe-2S)-binding domain protein
Aave_3928	ENOG4105RE0	Asp Glu hydantoin racemase
Aave_3931	ENOG4108UAU	isochorismatase
Aave_3932	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
Aave_3936	ENOG4105BZP	glycoside hydrolase 15-related
Aave_3939	ENOG4105CRW	Short chain fatty acid transporter
Aave_3943	ENOG4105F2Z	3-oxoadipate enol-lactonase
Aave_3944	ENOG4105CHU	acetyl-coa acetyltransferase
Aave_3945	ENOG4107QNJ	CoA-transferase subunit B
Aave_3947	ENOG4107HP6	Transcriptional regulator
Aave_3951	ENOG4106RE7	Cytochrome
Aave_3952	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Aave_3963	ENOG4105DHQ	Histidine kinase
Aave_3964	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Aave_3965	ENOG4105C0H	protease
Aave_3973	ENOG4105DEN	Luciferase family
Aave_3974	ENOG4105D7Q	type ii secretion system
Aave_3979	ENOG4105BZ1	(ABC) transporter
Aave_3980	ENOG4107RRY	Cyanophycin synthetase
Aave_3981	ENOG4105D9M	gamma-glutamylcysteine synthetase
Aave_3982	ENOG4108RH0	Crea protein
Aave_3988	ENOG4105CF1	Alkylated DNA repair protein
Aave_3992	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Aave_3994	ENOG4107Z5C	methylesterase
Aave_3995	ENOG4105BZU	Histidine kinase
Aave_3996	ENOG4105BZU	Histidine kinase
Aave_3998	ENOG4105BZU	Histidine kinase
Aave_4002	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Aave_4003	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Aave_4005	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Aave_4008	ENOG4105CNA	YD repeat protein
Aave_4008	ENOG4105CNA	YD repeat protein
Aave_4009	ENOG4105CS6	Rhs element vgr protein
Aave_4012	ENOG4105C7W	Xanthine dehydrogenase
Aave_4013	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
Aave_4014	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
Aave_4019	ENOG4108RCM	Nitroreductase
Aave_4022	ENOG4105CGH	5'-nucleotidase
Aave_4023	ENOG4105DUM	transcriptional regulator, lysR family
Aave_4024	ENOG4105HMI	Membrane
Aave_4026	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Aave_4031	ENOG4105E5G	Alpha beta hydrolase fold
Aave_4033	ENOG4105EVH	UPF0753 protein
Aave_4034	ENOG4108TWJ	NADH dehydrogenase subunit 5
Aave_4036	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Aave_4038	ENOG4108TQ9	Histidine kinase
Aave_4039	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Aave_4044	ENOG4105ETT	transcriptional Regulator, LysR family
Aave_4045	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Aave_4047	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
Aave_4048	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Aave_4049	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Aave_4052	ENOG4108UJD	30S ribosomal protein S9
Aave_4053	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Aave_4054	ENOG4107QPV	Serine Threonine protein kinase
Aave_4055	ENOG4105D6S	protein involved in catabolism of external DNA
Aave_4058	ENOG4105SYT	Methylenetetrahydrofolate reductase
Aave_4060	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Aave_4062	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Aave_4068	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Aave_4070	ENOG4105CDA	abc transporter atp-binding protein
Aave_4071	ENOG4105DRP	amino acid AbC transporter
Aave_4072	ENOG4105EAD	ABC transporter
Aave_4073	ENOG4107RP9	extracellular solute-binding protein, family 3
Aave_4074	ENOG4107RP9	extracellular solute-binding protein, family 3
Aave_4075	ENOG4107YNJ	LysR family Transcriptional regulator
Aave_4076	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
Aave_4077	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Aave_4078	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Aave_4079	ENOG4108JJ7	ABC transporter
Aave_4080	ENOG4105NAU	thioesterase Superfamily protein
Aave_4083	ENOG41060WC	Enoyl-CoA hydratase
Aave_4085	ENOG4105CHU	acetyl-coa acetyltransferase
Aave_4089	ENOG4105CSU	acyl-Coa dehydrogenase
Aave_4136	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
Aave_4138	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Aave_4139	ENOG4105CAS	nag kinase
Aave_4145	ENOG4105EY8	ABC transporter
Aave_4147	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Aave_4150	ENOG4105GVR	general secretion pathway protein D
Aave_4157	ENOG4105WMT	general secretion pathway protein h
Aave_4158	ENOG4108VAU	general secretion pathway protein G
Aave_4159	ENOG4105D7Q	type ii secretion system
Aave_4160	ENOG4107QHF	type ii secretion system protein e
Aave_4163	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Aave_4165	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Aave_4169	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Aave_4170	ENOG4109066	lysm domain bon superfamily protein
Aave_4174	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
Aave_4175	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
Aave_4177	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Aave_4178	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
Aave_4179	ENOG4105NQN	cytochrome C
Aave_4181	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
Aave_4182	ENOG4105HDK	L-asparaginase
Aave_4184	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Aave_4185	ENOG4108JU5	Magnesium and cobalt efflux protein
Aave_4188	ENOG4108YXU	transcriptional regulator AsnC family
Aave_4189	ENOG4107IFA	Lipase (EC 3.1.1.3)
Aave_4193	ENOG4105MIR	Phenylalanine 4-monooxygenase
Aave_4195	ENOG4105CEY	Amp-dependent synthetase and ligase
Aave_4196	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Aave_4197	ENOG4105C2J	ABC transporter
Aave_4198	ENOG4105CNN	ABC, transporter
Aave_4199	ENOG4105ETE	Transcriptional regulator (LacI family
Aave_4200	ENOG4108RVA	ribokinase
Aave_4201	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
Aave_4203	ENOG4105E4C	Lytic transglycosylase catalytic
Aave_4204	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Aave_4205	ENOG4105BZU	Histidine kinase
Aave_4208	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Aave_4210	ENOG4108K4C	ec 3.1.3.12
Aave_4211	ENOG4105BZP	glycoside hydrolase 15-related
Aave_4212	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
Aave_4218	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
Aave_4221	ENOG4105DY8	decarboxylase
Aave_4222	ENOG4107RP9	extracellular solute-binding protein, family 3
Aave_4227	ENOG4105VCD	cytoplasmic protein
Aave_4228	ENOG4105D22	carbon starvation protein
Aave_4229	ENOG4105WH1	Two component transcriptional regulator luxr family
Aave_4231	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Aave_4233	ENOG4105CVJ	phosphoglycerate mutase
Aave_4237	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Aave_4240	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Aave_4241	ENOG4105C9A	Phoh family
Aave_4242	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Aave_4243	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Aave_4245	ENOG4105C1J	atp-dependent rna helicase
Aave_4246	ENOG4105FYV	Amp nucleosidase
Aave_4247	ENOG4105BZU	Histidine kinase
Aave_4250	ENOG4105DM4	PTS System
Aave_4251	ENOG4105DE4	1-phosphofructokinase
Aave_4252	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Aave_4256	ENOG4105F7F	Chaperone
Aave_4258	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
Aave_4259	ENOG4105CJ1	ABC, transporter
Aave_4261	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Aave_4263	ENOG4107XC4	flavin reductase domain protein, FMN-binding
Aave_4266	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
Aave_4268	ENOG4105ERH	Fumarylacetoacetate hydrolase
Aave_4271	ENOG4105K56	Transcriptional regulator
Aave_4272	ENOG4108ZHJ	Organic hydroperoxide resistance protein
Aave_4274	ENOG4105D9P	serine threonine protein kinase
Aave_4276	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Aave_4279	ENOG4105BZU	Histidine kinase
Aave_4283	ENOG4105CNA	YD repeat protein
Aave_4289	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
Aave_4291	ENOG4105FE9	pseudouridine synthase
Aave_4292	ENOG4105BZU	Histidine kinase
Aave_4294	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_4295	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
Aave_4298	ENOG4105X23	Endonuclease Exonuclease phosphatase
Aave_4299	ENOG4105DZQ	phospholipase D Transphosphatidylase
Aave_4300	ENOG4107UXM	Membrane
Aave_4301	ENOG4105DZ0	fad dependent oxidoreductase
Aave_4303	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_4305	ENOG4105MP9	class II Aldolase
Aave_4306	ENOG4105C10	Electron transfer flavoprotein
Aave_4307	ENOG4105BZJ	Electron transfer flavoprotein
Aave_4310	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Aave_4311	ENOG4105E39	Enoyl-CoA hydratase
Aave_4312	ENOG4105C1G	acyl-Coa dehydrogenase
Aave_4313	ENOG4105CC9	acyl-Coa dehydrogenase
Aave_4314	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Aave_4315	ENOG4105CC0	LysR family Transcriptional regulator
Aave_4316	ENOG4105D0M	Protease HtpX homolog
Aave_4319	ENOG4105EKE	dihydroorotase
Aave_4320	ENOG4105EB3	Histidine kinase
Aave_4321	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Aave_4324	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Aave_4325	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
Aave_4330	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Aave_4333	ENOG4108JPW	Aminotransferase
Aave_4341	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Aave_4343	ENOG4108Z9W	Outer membrane porin
Aave_4344	ENOG4108Z9W	Outer membrane porin
Aave_4345	ENOG4105CSH	Transporter
Aave_4349	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Aave_4350	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
Aave_4353	ENOG4108IPT	Naphthoate synthase
Aave_4354	ENOG4107QX3	carboxylase
Aave_4355	ENOG4105CEY	Amp-dependent synthetase and ligase
Aave_4360	ENOG4107YBY	Hydrolase
Aave_4361	ENOG4105BZU	Histidine kinase
Aave_4362	ENOG4105K5B	UPF0225 protein
Aave_4364	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
Aave_4365	ENOG4105C1G	acyl-Coa dehydrogenase
Aave_4368	ENOG4105CHU	acetyl-coa acetyltransferase
Aave_4369	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
Aave_4370	ENOG41077A9	carbonic anhydrase
Aave_4371	ENOG4105C1G	acyl-Coa dehydrogenase
Aave_4372	ENOG4108Z6Z	Transcriptional regulator
Aave_4373	ENOG4105C5H	ABC transporter
Aave_4374	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Aave_4375	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Aave_4376	ENOG4105BZU	Histidine kinase
Aave_4377	ENOG4108V3W	Chemotaxis protein, CheW
Aave_4378	ENOG4105CBS	Chea signal transduction histidine kinase
Aave_4379	ENOG4108VYJ	response regulator receiver protein
Aave_4381	ENOG4105BZU	Histidine kinase
Aave_4382	ENOG4105WH1	Two component transcriptional regulator luxr family
Aave_4383	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Aave_4384	ENOG4105VS8	Flagellar biosynthetic protein fliq
Aave_4385	ENOG4105CN7	Flagellar biosynthetic protein FliP
Aave_4387	ENOG4105DD5	Flagellar motor switch protein
Aave_4388	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Aave_4389	ENOG4107ZI8	flagellar basal body-associated protein flil
Aave_4392	ENOG4108JIR	Flagellum-specific ATP synthase
Aave_4394	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Aave_4395	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
Aave_4396	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
Aave_4398	ENOG4105MQ3	flagellar protein FliS
Aave_4399	ENOG4105DTS	flagellar hook-associated
Aave_4405	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Aave_4406	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Aave_4408	ENOG4107RD7	Flagellar Motor Protein, MotA
Aave_4409	ENOG4105ER2	Ompa motb domain protein
Aave_4410	ENOG4108VYJ	response regulator receiver protein
Aave_4411	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
Aave_4412	ENOG4105D00	flagellar biosynthetic protein flhB
Aave_4413	ENOG4105D7B	Flagellar biosynthesis protein flha
Aave_4414	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Aave_4416	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Aave_4420	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Aave_4421	ENOG4108ZC9	flagellar basal-body rod protein flgc
Aave_4422	ENOG4105W00	Flagellar hook capping protein
Aave_4423	ENOG4105BZE	flagellar hook protein, FlgE
Aave_4424	ENOG4108KPB	Flagellar basal-body rod protein FlgF
Aave_4425	ENOG4105CGA	flagellar basal-body rod protein FlgG
Aave_4428	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Aave_4429	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
Aave_4430	ENOG4105E1Q	flagellar hook-associated protein
Aave_4431	ENOG4105DTJ	flagellar hook-associated protein
Aave_4434	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Aave_4436	ENOG4105T38	integral membrane protein
Aave_4437	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Aave_4438	ENOG4108TGY	Glutathione S-transferase
Aave_4439	ENOG4105JAB	phenazine biosynthesis protein, phzf family
Aave_4446	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_4455	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Aave_4461	ENOG4105DU1	integral membrane protein, terc
Aave_4462	ENOG41063Z6	transcriptional regulator, lysR family
Aave_4466	ENOG41061MV	Arylsulfatase
Aave_4467	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Aave_4469	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Aave_4471	ENOG4105C25	Primosomal protein n'
Aave_4475	ENOG4105C4R	Atp-dependent dna helicase
Aave_4476	ENOG4105HDD	phospholipase
Aave_4479	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Aave_4486	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Aave_4492	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
Aave_4493	ENOG4105K6H	D-cysteine desulfhydrase
Aave_4495	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_4505	ENOG4105E1J	oxidoreductase
Aave_4507	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Aave_4511	ENOG4105M2Z	protein tyrosine serine phosphatase
Aave_4512	ENOG4105CHR	reductase
Aave_4514	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Aave_4515	ENOG4105D7T	ABC transporter
Aave_4518	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
Aave_4520	ENOG4105CAF	HipA N-terminal domain protein
Aave_4523	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Aave_4526	ENOG4105ES5	Histidine kinase
Aave_4528	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Aave_4530	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Aave_4531	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Aave_4532	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Aave_4533	ENOG4108VZM	50s ribosomal protein L10
Aave_4534	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Aave_4535	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Aave_4536	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Aave_4537	ENOG4105PM1	preprotein translocase subunit SecE
Aave_4538	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Aave_4539	ENOG4105D7Z	glutathione synthase
Aave_4540	ENOG4105DKK	Benzoate
Aave_4541	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Aave_4543	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Aave_4544	ENOG4105C1A	potassium transporter peripheral membrane
Aave_4545	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Aave_4548	ENOG4105C8T	Leucyl-tRNA synthetase
Aave_4550	ENOG4105BZU	Histidine kinase
Aave_4551	ENOG4105SG9	biopolymer transport protein, ExbD
Aave_4553	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Aave_4554	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Aave_4555	ENOG41090R7	Ferric uptake
Aave_4556	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
Aave_4557	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
Aave_4558	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
Aave_4559	ENOG4105C8V	SAICAR synthetase
Aave_4561	ENOG4105K63	Thioredoxin
Aave_4562	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Aave_4563	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Aave_4564	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Aave_4569	ENOG41072GX	Peptidase M22 Glycoprotease
Aave_4572	ENOG4107QUT	magnesium and cobalt transport protein CorA
Aave_4574	ENOG4105CEY	Amp-dependent synthetase and ligase
Aave_4576	ENOG4105D2N	Aldolase
Aave_4578	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Aave_4581	ENOG4105CA9	Pyruvate kinase
Aave_4582	ENOG4107RAQ	aminopeptidase
Aave_4583	ENOG4108S0S	Nucleotidyl transferase
Aave_4584	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Aave_4585	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Aave_4588	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Aave_4592	ENOG4105CDV	Ompa motb domain protein
Aave_4605	ENOG4105EUB	pirin domain protein
Aave_4608	ENOG4105D64	Mechanosensitive ion channel
Aave_4610	ENOG4105DIJ	Phosphoethanolamine transferase
Aave_4611	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
Aave_4614	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
Aave_4623	ENOG4105HHM	rdd domain containing protein
Aave_4627	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Aave_4629	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Aave_4635	ENOG4105DUM	transcriptional regulator, lysR family
Aave_4637	ENOG4105DHQ	Histidine kinase
Aave_4640	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Aave_4641	ENOG4108004	Modulates RecA activity (By similarity)
Aave_4643	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Aave_4644	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Aave_4645	ENOG4105VIE	preprotein translocase, subunit YajC
Aave_4647	ENOG4105F7P	transcriptional regulator AsnC family
Aave_4649	ENOG4107SFI	Major Facilitator superfamily
Aave_4651	ENOG4105CA3	membrane-bound lytic murein transglycosylase
Aave_4654	ENOG4105BZU	Histidine kinase
Aave_4657	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Aave_4658	ENOG4105CEY	Amp-dependent synthetase and ligase
Aave_4661	ENOG4108IG5	Transcriptional regulator
Aave_4666	ENOG4105CPI	Metal Dependent Phosphohydrolase
Aave_4668	ENOG4108U78	Glutathione S-transferase
Aave_4669	ENOG4107QTF	adenylosuccinate lyase
Aave_4670	ENOG4108VWS	Yaeq family
Aave_4673	ENOG4108ZCF	integral membrane protein
Aave_4675	ENOG41086DT	Membrane protein of unknown function
Aave_4676	ENOG4105ERG	peptidase m48, ste24p
Aave_4677	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Aave_4678	ENOG4108YSG	O-Antigen polymerase
Aave_4680	ENOG4105Q36	FHA domain containing protein
Aave_4682	ENOG4108ZCF	integral membrane protein
Aave_4683	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Aave_4684	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Aave_4685	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Aave_4686	ENOG4105C79	DNA protecting protein DprA
Aave_4688	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Aave_4690	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Aave_4693	ENOG4105BZA	Phosphoglycerate kinase
Aave_4695	ENOG4108594	Permease of the drug metabolite transporter
Aave_4696	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
Aave_4702	ENOG4108594	Permease of the drug metabolite transporter
Aave_4703	ENOG4105C8Q	Methyl-accepting chemotaxis
Aave_4709	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
Aave_4711	ENOG4107RDB	Major Facilitator
Aave_4713	ENOG4108UUM	single-stranded DNA-binding protein
Aave_4718	ENOG41080HT	Transcriptional regulator, arsr family
Aave_4723	ENOG4105DAA	L-lactate
Aave_4724	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Aave_4730	ENOG4105BZU	Histidine kinase
Aave_4731	ENOG4108R6K	riboflavin synthase, subunit alpha
Aave_4737	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Aave_4743	ENOG4105EVZ	LysR family transcriptional regulator
Aave_4744	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Aave_4746	ENOG4105C26	Dehydrogenase
Aave_4748	ENOG4105BZU	Histidine kinase
Aave_4749	ENOG4108PVQ	transcriptional regulator
Aave_4752	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Aave_4753	ENOG4105C0Z	ABC transporter
Aave_4754	ENOG4108IV0	ABC, transporter
Aave_4755	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
Aave_4759	ENOG4105C6K	Malic enzyme
Aave_4762	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Aave_4763	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Aave_4764	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
Aave_4765	ENOG4105EHM	Aminoglycoside phosphotransferase
Aave_4766	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Aave_4769	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Aave_4770	ENOG4105DXI	Major Facilitator superfamily
Aave_4772	ENOG4108K3Z	AraC family transcriptional regulator
Aave_4773	ENOG4105C85	amino acid
Aave_4774	ENOG4105CPD	ethanolamine ammonia-lyase
Aave_4775	ENOG4107FQ9	ethanolamine ammonia-lyase
Aave_4776	ENOG4105BZU	Histidine kinase
Aave_4777	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Aave_4778	ENOG4105DWV	Homoserine O-trans-acetylase
Aave_4780	ENOG4105VFU	Rna-binding protein
Aave_4781	ENOG4105VFU	Rna-binding protein
Aave_4782	ENOG4107FW0	short-chain dehydrogenase reductase
Aave_4784	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Aave_4785	ENOG4105C2X	Arabinose 5-phosphate isomerase
Aave_4787	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Aave_4788	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
Aave_4791	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Aave_4793	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Aave_4794	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Aave_4795	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Aave_4796	ENOG4105VG0	50S ribosomal protein l34