locus-tag	class	description
FRC90_00025	COG0583	DNA-binding transcription factor activity
FRC90_00040	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FRC90_00045	COG1126	abc transporter atp-binding protein
FRC90_00050	COG0765	amino acid transport
FRC90_00055	COG0765	amino acid transport
FRC90_00075	COG0646	methionine synthase
FRC90_00075	COG1410	methionine synthase
FRC90_00125	COG0583	DNA-binding transcription factor activity
FRC90_00135	COG0840	transmembrane signaling receptor activity
FRC90_00140	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_00145	COG4191	Histidine kinase
FRC90_00155	COG0606	chelatase, subunit chli
FRC90_00165	COG0347	Belongs to the P(II) protein family
FRC90_00170	COG0004	ammonium transporteR
FRC90_00215	COG0277	FAD linked oxidase domain protein
FRC90_00225	COG0247	lactate metabolic process
FRC90_00255	COG0386	Belongs to the glutathione peroxidase family
FRC90_00265	COG0477	Major facilitator Superfamily
FRC90_00270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FRC90_00280	COG0747	negative chemotaxis
FRC90_00300	COG0625	glutathione transferase activity
FRC90_00305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FRC90_00350	COG1215	transferase activity, transferring glycosyl groups
FRC90_00370	COG0477	Major facilitator Superfamily
FRC90_00385	COG0745	RESPONSE REGULATOR receiver
FRC90_00390	COG2211	Major facilitator Superfamily
FRC90_00410	COG0501	Belongs to the peptidase M48B family
FRC90_00415	COG0471	metal ion transport
FRC90_00420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FRC90_00440	COG0583	DNA-binding transcription factor activity
FRC90_00445	COG2814	Major facilitator Superfamily
FRC90_00455	COG0708	Exodeoxyribonuclease III
FRC90_00460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FRC90_00470	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FRC90_00475	COG0154	amidase activity
FRC90_00480	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FRC90_00485	COG1077	Cell shape determining protein MreB Mrl
FRC90_00495	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FRC90_00500	COG0768	penicillin binding
FRC90_00515	COG0765	amino acid transport
FRC90_00520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_00525	COG1760	l-serine dehydratase
FRC90_00545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FRC90_00550	COG1127	ABC transporter
FRC90_00575	COG3237	CsbD-like
FRC90_00595	COG4452	Inner membrane protein CreD
FRC90_00600	COG2205	protein histidine kinase activity
FRC90_00605	COG0745	RESPONSE REGULATOR receiver
FRC90_00610	COG2095	MarC family integral membrane protein
FRC90_00615	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_00620	COG0412	Dienelactone hydrolase
FRC90_00630	COG1566	PFAM secretion protein HlyD family protein
FRC90_00640	COG1846	Transcriptional regulator
FRC90_00645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FRC90_00645	COG0519	Catalyzes the synthesis of GMP from XMP
FRC90_00650	COG0598	Magnesium transport protein CorA
FRC90_00660	COG1981	membrane
FRC90_00675	COG2945	thiolester hydrolase activity
FRC90_00680	COG1686	Belongs to the peptidase S11 family
FRC90_00685	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FRC90_00690	COG0049	tRNA binding
FRC90_00695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FRC90_00700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FRC90_00705	COG0051	transcription antitermination factor activity, RNA binding
FRC90_00710	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FRC90_00715	COG0088	Forms part of the polypeptide exit tunnel
FRC90_00720	COG0089	rRNA binding
FRC90_00725	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FRC90_00730	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FRC90_00735	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FRC90_00740	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FRC90_00745	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FRC90_00750	COG0255	Belongs to the universal ribosomal protein uL29 family
FRC90_00755	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FRC90_00760	COG0678	peroxiredoxin activity
FRC90_00770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FRC90_00785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FRC90_00790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FRC90_00805	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FRC90_00810	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FRC90_00815	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FRC90_00820	COG2205	protein histidine kinase activity
FRC90_00825	COG0745	RESPONSE REGULATOR receiver
FRC90_00840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FRC90_00845	COG0321	lipoyl(octanoyl) transferase activity
FRC90_00850	COG2921	Belongs to the UPF0250 family
FRC90_00860	COG0356	it plays a direct role in the translocation of protons across the membrane
FRC90_00870	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FRC90_00875	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FRC90_00880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FRC90_00885	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FRC90_00890	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FRC90_00895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FRC90_00900	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FRC90_00900	COG1793	dna ligase
FRC90_00905	COG1793	dna ligase
FRC90_00910	COG1201	RNA secondary structure unwinding
FRC90_00960	COG3245	cytochrome
FRC90_00975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC90_00980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC90_01065	COG0121	glutamine amidotransferase
FRC90_01070	COG2814	Major facilitator Superfamily
FRC90_01075	COG1942	4-Oxalocrotonate Tautomerase
FRC90_01090	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FRC90_01120	COG0018	arginyl-trna synthetase
FRC90_01130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FRC90_01140	COG1137	ATPase activity
FRC90_01145	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FRC90_01150	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FRC90_01170	COG4178	(ABC) transporter
FRC90_01180	COG0653	protein targeting
FRC90_01185	COG0659	secondary active sulfate transmembrane transporter activity
FRC90_01200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FRC90_01220	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FRC90_01235	COG2967	ApaG domain
FRC90_01240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FRC90_01250	COG0546	phosphoglycolate phosphatase activity
FRC90_01270	COG2207	Transcriptional regulator
FRC90_01300	COG4794	Type iii secretion
FRC90_01305	COG4790	Type iii secretion
FRC90_01320	COG4789	Type iii secretion
FRC90_01325	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FRC90_01445	COG0500	methyltransferase
FRC90_01450	COG0739	heme binding
FRC90_01450	COG0741	lytic transglycosylase activity
FRC90_01450	COG1196	nuclear chromosome segregation
FRC90_01475	COG0512	Glutamine amidotransferase of anthranilate synthase
FRC90_01480	COG1280	lysine exporter protein (LysE YggA)
FRC90_01485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FRC90_01490	COG0134	indole-3-glycerol-phosphate synthase activity
FRC90_01495	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FRC90_01535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FRC90_01545	COG0783	Belongs to the Dps family
FRC90_01550	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FRC90_01565	COG0463	Glycosyl transferase, family 2
FRC90_01580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FRC90_01590	COG3842	ATPase activity
FRC90_01595	COG3842	ATPase activity
FRC90_01605	COG0395	ABC-type sugar transport system, permease component
FRC90_01625	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FRC90_01630	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FRC90_01635	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FRC90_01640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FRC90_01645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FRC90_01650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FRC90_01655	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FRC90_01660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FRC90_01665	COG1841	ribosomal large subunit assembly
FRC90_01670	COG0200	Binds to the 23S rRNA
FRC90_01675	COG0201	protein transport
FRC90_01680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FRC90_01685	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FRC90_01690	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FRC90_01695	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FRC90_01700	COG0202	RNA polymerase activity
FRC90_01705	COG0203	ribosomal protein L17
FRC90_01715	COG0443	Heat shock 70 kDa protein
FRC90_01720	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FRC90_01725	COG0792	nuclease activity
FRC90_01730	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FRC90_01735	COG2823	Periplasmic or secreted lipoprotein
FRC90_01740	COG2084	Dehydrogenase
FRC90_01750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FRC90_01775	COG2733	membrane
FRC90_01795	COG0277	FAD linked oxidase domain protein
FRC90_01805	COG0583	DNA-binding transcription factor activity
FRC90_01825	COG1285	pathogenesis
FRC90_01835	COG3850	Histidine kinase
FRC90_01840	COG2197	response regulator
FRC90_01855	COG4771	TonB-dependent receptor
FRC90_01870	COG2223	nitrite transmembrane transporter activity
FRC90_01875	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FRC90_01880	COG1140	nitrate reductase beta subunit
FRC90_01885	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FRC90_01890	COG2181	nitrate reductase activity
FRC90_01895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC90_01900	COG0288	reversible hydration of carbon dioxide
FRC90_01915	COG3945	hemerythrin HHE cation binding domain
FRC90_01930	COG0477	Major facilitator Superfamily
FRC90_01975	COG1272	protein, Hemolysin III
FRC90_01990	COG3706	GGDEF domain
FRC90_02000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC90_02005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC90_02015	COG0129	dihydroxy-acid dehydratase activity
FRC90_02020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_02030	COG0583	DNA-binding transcription factor activity
FRC90_02035	COG1741	Belongs to the pirin family
FRC90_02040	COG1335	isochorismatase
FRC90_02080	COG0243	molybdopterin cofactor binding
FRC90_02095	COG1473	amidohydrolase
FRC90_02105	COG0840	transmembrane signaling receptor activity
FRC90_02120	COG0519	Catalyzes the synthesis of GMP from XMP
FRC90_02125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC90_02180	COG3409	Peptidoglycan-binding domain 1 protein
FRC90_02180	COG3267	Type II secretory pathway component ExeA
FRC90_02185	COG3266	domain, Protein
FRC90_02200	COG4269	membrane
FRC90_02235	COG0625	glutathione transferase activity
FRC90_02240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FRC90_02250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FRC90_02255	COG1649	PFAM Uncharacterised BCR, COG1649
FRC90_02275	COG3447	MASE1 domain protein
FRC90_02275	COG5001	Diguanylate cyclase
FRC90_02275	COG5002	protein histidine kinase activity
FRC90_02280	COG0523	cobalamin synthesis protein
FRC90_02295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FRC90_02300	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FRC90_02305	COG2001	Belongs to the MraZ family
FRC90_02310	COG0275	rRNA processing
FRC90_02315	COG3116	cell division
FRC90_02325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC90_02330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FRC90_02335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FRC90_02340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FRC90_02345	COG0772	Belongs to the SEDS family
FRC90_02350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FRC90_02355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FRC90_02360	COG1181	Belongs to the D-alanine--D-alanine ligase family
FRC90_02365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FRC90_02375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FRC90_02380	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FRC90_02385	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FRC90_02390	COG0840	transmembrane signaling receptor activity
FRC90_02405	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FRC90_02410	COG0575	Belongs to the CDS family
FRC90_02435	COG1414	Transcriptional regulator
FRC90_02440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC90_02445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FRC90_02455	COG0557	exoribonuclease II activity
FRC90_02465	COG3150	esterase
FRC90_02470	COG0772	Belongs to the SEDS family
FRC90_02475	COG0154	amidase activity
FRC90_02480	COG0312	modulator of DNA gyrase
FRC90_02490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FRC90_02500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FRC90_02510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FRC90_02515	COG0511	ligase activity, forming carbon-carbon bonds
FRC90_02520	COG0439	Biotin carboxylase
FRC90_02525	COG2264	protein methyltransferase activity
FRC90_02535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FRC90_02545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FRC90_02580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FRC90_02590	COG2204	response regulator
FRC90_02600	COG2205	protein histidine kinase activity
FRC90_02605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FRC90_02630	COG0431	NADPH-dependent FMN reductase
FRC90_02635	COG3829	transcription factor binding
FRC90_02640	COG1024	Enoyl-CoA hydratase
FRC90_02655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FRC90_02665	COG0012	GTP binding
FRC90_02680	COG0517	IMP dehydrogenase activity
FRC90_02680	COG1125	glycine betaine transport
FRC90_02690	COG1238	metal cluster binding
FRC90_02700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC90_02705	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FRC90_02710	COG0138	bifunctional purine biosynthesis protein purh
FRC90_02720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FRC90_02725	COG0351	phosphomethylpyrimidine kinase
FRC90_02725	COG0352	thiamine-phosphate diphosphorylase activity
FRC90_02725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FRC90_02730	COG1773	rubredoxin
FRC90_02745	COG0835	chemotaxis
FRC90_02750	COG0840	transmembrane signaling receptor activity
FRC90_02755	COG0643	Histidine kinase
FRC90_02755	COG2198	Histidine kinase
FRC90_02760	COG0415	Belongs to the DNA photolyase family
FRC90_02765	COG1678	Uncharacterized ACR, COG1678
FRC90_02770	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FRC90_02775	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FRC90_02780	COG0540	Belongs to the ATCase OTCase family
FRC90_02800	COG3842	ATPase activity
FRC90_02805	COG1178	ABC-type Fe3 transport system permease component
FRC90_02855	COG4970	Tfp pilus assembly protein FimT
FRC90_02875	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FRC90_02880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC90_02885	COG1765	OsmC-like protein
FRC90_02890	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FRC90_02910	COG1473	amidohydrolase
FRC90_02915	COG0747	negative chemotaxis
FRC90_02920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC90_02925	COG0444	Belongs to the ABC transporter superfamily
FRC90_02930	COG4608	Belongs to the ABC transporter superfamily
FRC90_02935	COG0840	transmembrane signaling receptor activity
FRC90_02955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FRC90_02960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FRC90_02965	COG0166	Belongs to the GPI family
FRC90_02970	COG0459	protein refolding
FRC90_02975	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FRC90_02990	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FRC90_03025	COG2226	methyltransferase
FRC90_03030	COG0438	transferase activity, transferring glycosyl groups
FRC90_03040	COG0367	asparagine synthase
FRC90_03045	COG0438	transferase activity, transferring glycosyl groups
FRC90_03050	COG0367	asparagine synthase
FRC90_03070	COG1216	Glycosyl transferase, family 2
FRC90_03080	COG1309	transcriptional regulator
FRC90_03085	COG0493	'glutamate synthase
FRC90_03095	COG1953	Uracil, thiamine, allantoin
FRC90_03130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FRC90_03130	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FRC90_03135	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FRC90_03150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FRC90_03160	COG1560	Kdo2-lipid A biosynthetic process
FRC90_03170	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FRC90_03180	COG1333	cytochrome c biogenesis protein
FRC90_03185	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FRC90_03190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FRC90_03195	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FRC90_03225	COG1965	Belongs to the frataxin family
FRC90_03265	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FRC90_03270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FRC90_03275	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FRC90_03295	COG0067	glutamate synthase
FRC90_03295	COG0069	glutamate synthase activity
FRC90_03295	COG0070	glutamate synthase
FRC90_03305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_03310	COG0765	amino acid transport
FRC90_03315	COG1126	abc transporter atp-binding protein
FRC90_03320	COG1127	ABC transporter
FRC90_03325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FRC90_03330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FRC90_03335	COG2853	Lipoprotein
FRC90_03355	COG1131	(ABC) transporter
FRC90_03360	COG0842	Transport permease protein
FRC90_03365	COG5007	Belongs to the BolA IbaG family
FRC90_03370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FRC90_03375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FRC90_03380	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FRC90_03410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FRC90_03415	COG0131	Imidazoleglycerol-phosphate dehydratase
FRC90_03425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FRC90_03445	COG0438	transferase activity, transferring glycosyl groups
FRC90_03475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FRC90_03480	COG1301	dicarboxylic acid transport
FRC90_03490	COG0107	imidazoleglycerol-phosphate synthase activity
FRC90_03495	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FRC90_03500	COG0140	phosphoribosyl-ATP diphosphatase activity
FRC90_03515	COG0537	adenosine 5'-monophosphoramidase activity
FRC90_03520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FRC90_03525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FRC90_03530	COG0805	protein transport
FRC90_03550	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FRC90_03570	COG0714	Associated with various cellular activities
FRC90_03575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC90_03580	COG0084	hydrolase, TatD family'
FRC90_03590	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FRC90_03595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FRC90_03645	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_03650	COG0840	transmembrane signaling receptor activity
FRC90_03655	COG0829	nickel cation binding
FRC90_03675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FRC90_03700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_03705	COG1116	anion transmembrane transporter activity
FRC90_03720	COG0280	phosphate acetyltransferase
FRC90_03720	COG0281	malic enzyme
FRC90_03740	COG1953	Uracil, thiamine, allantoin
FRC90_03745	COG2186	Transcriptional regulator
FRC90_03750	COG0840	transmembrane signaling receptor activity
FRC90_03755	COG1301	dicarboxylic acid transport
FRC90_03785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FRC90_03800	COG2186	Transcriptional regulator
FRC90_03810	COG0405	Gamma-glutamyltransferase
FRC90_03850	COG0251	oxidation-reduction process
FRC90_03870	COG5001	Diguanylate cyclase
FRC90_03870	COG5002	protein histidine kinase activity
FRC90_03870	COG3447	MASE1 domain protein
FRC90_03885	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_03905	COG3845	ABC transporter
FRC90_03910	COG4603	Belongs to the binding-protein-dependent transport system permease family
FRC90_03935	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FRC90_03945	COG2366	antibiotic biosynthetic process
FRC90_03950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FRC90_03960	COG0402	S-adenosylhomocysteine deaminase activity
FRC90_03965	COG0717	Belongs to the dCTP deaminase family
FRC90_03980	COG2321	neutral zinc metallopeptidase
FRC90_03985	COG0513	Belongs to the DEAD box helicase family
FRC90_03990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FRC90_03995	COG2916	Histone family protein nucleoid-structuring protein H-NS
FRC90_04000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FRC90_04020	COG3483	tryptophan 2,3-dioxygenase activity
FRC90_04030	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FRC90_04035	COG1522	sequence-specific DNA binding
FRC90_04040	COG0727	PFAM Uncharacterised protein family (UPF0153)
FRC90_04065	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FRC90_04070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FRC90_04085	COG0268	Binds directly to 16S ribosomal RNA
FRC90_04090	COG0728	peptidoglycan biosynthetic process
FRC90_04100	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FRC90_04100	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FRC90_04110	COG3022	response to hydroperoxide
FRC90_04115	COG1530	ribonuclease E activity
FRC90_04140	COG0616	signal peptide processing
FRC90_04140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FRC90_04145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FRC90_04150	COG0424	maF-like protein
FRC90_04155	COG1399	metal-binding, possibly nucleic acid-binding protein
FRC90_04160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FRC90_04165	COG0416	fatty acid biosynthetic process
FRC90_04170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FRC90_04175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FRC90_04180	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_04185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FRC90_04190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FRC90_04215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC90_04220	COG0481	GTPase activity
FRC90_04225	COG0681	Belongs to the peptidase S26 family
FRC90_04235	COG0571	ribonuclease III activity
FRC90_04240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FRC90_04245	COG1381	Involved in DNA repair and RecF pathway recombination
FRC90_04250	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FRC90_04255	COG1472	Belongs to the glycosyl hydrolase 3 family
FRC90_04260	COG3064	Membrane
FRC90_04270	COG2203	Gaf domain
FRC90_04270	COG3706	GGDEF domain
FRC90_04270	COG4251	negative regulation of phosphorylation
FRC90_04270	COG5001	Diguanylate cyclase
FRC90_04275	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FRC90_04300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FRC90_04315	COG0762	integral membrane protein
FRC90_04320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FRC90_04325	COG0159	tryptophan synthase activity
FRC90_04330	COG0133	tryptophan synthase activity
FRC90_04335	COG0135	phosphoribosylanthranilate isomerase activity
FRC90_04340	COG0101	tRNA pseudouridine synthase activity
FRC90_04350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FRC90_04360	COG0473	3-isopropylmalate dehydrogenase activity
FRC90_04365	COG0066	3-isopropylmalate dehydratase activity
FRC90_04375	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FRC90_04385	COG0484	heat shock protein binding
FRC90_04390	COG0443	Heat shock 70 kDa protein
FRC90_04395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FRC90_04400	COG0360	Binds together with S18 to 16S ribosomal RNA
FRC90_04410	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FRC90_04415	COG0359	binds to the 23S rRNA
FRC90_04430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FRC90_04435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRC90_04485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FRC90_04490	COG0436	Aminotransferase
FRC90_04505	COG1763	Mo-molybdopterin cofactor biosynthetic process
FRC90_04510	COG0303	'Molybdopterin
FRC90_04515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FRC90_04520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC90_04545	COG0314	molybdopterin synthase activity
FRC90_04550	COG0542	response to heat
FRC90_04570	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FRC90_04580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC90_04595	COG0436	Aminotransferase
FRC90_04600	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FRC90_04605	COG1185	polyribonucleotide nucleotidyltransferase activity
FRC90_04610	COG0604	alcohol dehydrogenase
FRC90_04610	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_04610	COG3321	synthase
FRC90_04615	COG0149	triose-phosphate isomerase activity
FRC90_04630	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC90_04635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC90_04640	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC90_04645	COG0649	NAD binding
FRC90_04650	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FRC90_04655	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FRC90_04660	COG1034	ATP synthesis coupled electron transport
FRC90_04665	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FRC90_04670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC90_04680	COG0713	ATP synthesis coupled electron transport
FRC90_04695	COG1007	ATP synthesis coupled electron transport
FRC90_04755	COG0463	Glycosyl transferase, family 2
FRC90_04755	COG0457	Tetratricopeptide repeat
FRC90_04775	COG0071	Belongs to the small heat shock protein (HSP20) family
FRC90_04780	COG1136	(ABC) transporter
FRC90_04785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FRC90_04790	COG0702	epimerase
FRC90_04795	COG1733	regulation of RNA biosynthetic process
FRC90_04800	COG2267	carboxylic ester hydrolase activity
FRC90_04805	COG0584	glycerophosphoryl diester phosphodiesterase
FRC90_04815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FRC90_04820	COG0586	Pfam SNARE associated Golgi protein
FRC90_04825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC90_04840	COG0860	N-Acetylmuramoyl-L-alanine amidase
FRC90_04845	COG0802	atpase or kinase
FRC90_04850	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FRC90_04885	COG4974	Belongs to the 'phage' integrase family
FRC90_04890	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_04895	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FRC90_04900	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FRC90_04905	COG2833	Protein of unknown function (DUF455)
FRC90_04915	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FRC90_04925	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FRC90_04930	COG0148	phosphopyruvate hydratase activity
FRC90_04950	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FRC90_04955	COG0504	CTP synthase activity
FRC90_04960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FRC90_04965	COG0756	dUTP diphosphatase activity
FRC90_04975	COG1047	Peptidyl-prolyl cis-trans
FRC90_04980	COG2850	peptidyl-arginine hydroxylation
FRC90_04995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FRC90_05000	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FRC90_05005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC90_05025	COG0741	lytic transglycosylase activity
FRC90_05035	COG0840	transmembrane signaling receptor activity
FRC90_05040	COG0840	transmembrane signaling receptor activity
FRC90_05045	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FRC90_05085	COG2308	Evidence 4 Homologs of previously reported genes of
FRC90_05105	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FRC90_05115	COG4628	conserved protein (DUF2132)
FRC90_05125	COG0657	acetylesterase activity
FRC90_05130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC90_05155	COG4774	siderophore transport
FRC90_05200	COG3634	alkyl hydroperoxide reductase activity
FRC90_05225	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FRC90_05240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FRC90_05265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_05280	COG0583	DNA-binding transcription factor activity
FRC90_05285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC90_05295	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_05300	COG4948	Mandelate Racemase Muconate Lactonizing
FRC90_05345	COG0840	transmembrane signaling receptor activity
FRC90_05350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FRC90_05355	COG0358	DNA primase activity
FRC90_05360	COG5001	Diguanylate cyclase
FRC90_05360	COG3300	MHYT domain
FRC90_05365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_05370	COG0405	Gamma-glutamyltransferase
FRC90_05375	COG3540	Alkaline phosphatase
FRC90_05385	COG0604	alcohol dehydrogenase
FRC90_05385	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_05385	COG3321	synthase
FRC90_05390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FRC90_05395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FRC90_05405	COG0564	pseudouridine synthase activity
FRC90_05410	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FRC90_05415	COG1187	pseudouridine synthase activity
FRC90_05420	COG0105	UTP biosynthetic process
FRC90_05425	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FRC90_05430	COG3063	Type IV pilus biogenesis stability protein PilW
FRC90_05440	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FRC90_05445	COG0124	histidyl-tRNA synthetase
FRC90_05460	COG1160	GTP binding
FRC90_05465	COG1923	regulation of RNA biosynthetic process
FRC90_05470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FRC90_05475	COG0330	HflC and HflK could
FRC90_05480	COG0330	HflC and HflK could
FRC90_05485	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FRC90_05490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FRC90_05495	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FRC90_05525	COG1187	pseudouridine synthase activity
FRC90_05555	COG0174	glutamine synthetase
FRC90_05565	COG3852	Histidine kinase
FRC90_05570	COG2204	response regulator
FRC90_05580	COG0708	Exodeoxyribonuclease III
FRC90_05595	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FRC90_05605	COG0277	FAD linked oxidase domain protein
FRC90_05620	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FRC90_05645	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FRC90_05650	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FRC90_05655	COG0740	serine-type endopeptidase activity
FRC90_05660	COG0544	peptidyl-prolyl cis-trans isomerase activity
FRC90_05670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC90_05680	COG1562	ergosterol biosynthetic process
FRC90_05710	COG0631	protein serine/threonine phosphatase activity
FRC90_05725	COG2885	chlorophyll binding
FRC90_05790	COG1451	nucleotide metabolic process
FRC90_05795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_05800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FRC90_05805	COG2080	2 iron, 2 sulfur cluster binding
FRC90_05810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FRC90_05825	COG0114	fumarate hydratase activity
FRC90_05835	COG0745	RESPONSE REGULATOR receiver
FRC90_05840	COG2205	protein histidine kinase activity
FRC90_05845	COG2113	Glycine betaine
FRC90_05850	COG4176	ABC-type proline glycine betaine transport system permease component
FRC90_05855	COG4175	Glycine betaine
FRC90_05865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FRC90_05885	COG4654	Cytochrome c, class I
FRC90_05895	COG0129	dihydroxy-acid dehydratase activity
FRC90_05910	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FRC90_05915	COG1802	Transcriptional regulator
FRC90_05940	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_05950	COG0589	response to stress
FRC90_05960	COG2217	Heavy metal translocating P-type atpase
FRC90_05970	COG3278	Belongs to the heme-copper respiratory oxidase family
FRC90_06005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FRC90_06010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FRC90_06020	COG3437	response regulator, receiver
FRC90_06040	COG4206	TonB-dependent receptor
FRC90_06045	COG1797	cobyrinic acid a,c-diamide synthase activity
FRC90_06060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FRC90_06065	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FRC90_06070	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FRC90_06075	COG0778	Nitroreductase
FRC90_06080	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FRC90_06110	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_06115	COG1492	cobalamin metabolic process
FRC90_06120	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FRC90_06145	COG0477	Major facilitator Superfamily
FRC90_06165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FRC90_06170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC90_06175	COG2900	Belongs to the SlyX family
FRC90_06190	COG0513	Belongs to the DEAD box helicase family
FRC90_06215	COG1959	2 iron, 2 sulfur cluster binding
FRC90_06220	COG0583	DNA-binding transcription factor activity
FRC90_06235	COG0560	Phosphoserine phosphatase
FRC90_06245	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FRC90_06255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FRC90_06260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FRC90_06260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FRC90_06265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FRC90_06265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FRC90_06285	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_06295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FRC90_06330	COG0693	protein deglycase activity
FRC90_06340	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FRC90_06345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FRC90_06365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FRC90_06380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_06385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC90_06405	COG1446	asparaginase
FRC90_06410	COG4172	Belongs to the ABC transporter superfamily
FRC90_06420	COG0601	transmembrane transport
FRC90_06425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC90_06445	COG0322	excinuclease ABC activity
FRC90_06675	COG5484	DNA packaging
FRC90_06675	COG3728	DNA packaging
FRC90_06870	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FRC90_06880	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_06885	COG0028	Belongs to the TPP enzyme family
FRC90_06890	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_06910	COG2267	carboxylic ester hydrolase activity
FRC90_06960	COG1012	belongs to the aldehyde dehydrogenase family
FRC90_06965	COG2207	Transcriptional regulator
FRC90_06975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FRC90_07005	COG4651	solute:proton antiporter activity
FRC90_07005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FRC90_07015	COG0513	Belongs to the DEAD box helicase family
FRC90_07020	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FRC90_07025	COG0488	(ABC) transporter
FRC90_07040	COG3191	aminopeptidase activity
FRC90_07070	COG2132	Multicopper oxidase
FRC90_07100	COG0789	Transcriptional regulator
FRC90_07125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FRC90_07125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FRC90_07130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_07135	COG0052	Belongs to the universal ribosomal protein uS2 family
FRC90_07140	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FRC90_07145	COG0528	UMP kinase activity
FRC90_07150	COG0233	cytoplasmic translational termination
FRC90_07160	COG0575	Belongs to the CDS family
FRC90_07165	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FRC90_07170	COG0750	zinc metalloprotease
FRC90_07185	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC90_07190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FRC90_07195	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC90_07200	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC90_07205	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FRC90_07210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FRC90_07215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_07220	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_07225	COG1960	acyl-CoA dehydrogenase activity
FRC90_07230	COG0583	DNA-binding transcription factor activity
FRC90_07240	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FRC90_07245	COG0308	aminopeptidase N
FRC90_07255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FRC90_07270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FRC90_07275	COG0667	Aldo Keto reductase
FRC90_07280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FRC90_07285	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FRC90_07295	COG3577	Aspartyl protease
FRC90_07300	COG1666	GTP binding
FRC90_07310	COG0137	argininosuccinate synthase activity
FRC90_07315	COG3123	guanosine phosphorylase activity
FRC90_07325	COG1393	Belongs to the ArsC family
FRC90_07330	COG0285	dihydrofolate synthase activity
FRC90_07340	COG1286	toxin biosynthetic process
FRC90_07355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC90_07395	COG2814	Major facilitator Superfamily
FRC90_07400	COG2814	Major facilitator Superfamily
FRC90_07425	COG2183	response to ionizing radiation
FRC90_07440	COG1454	alcohol dehydrogenase
FRC90_07450	COG0657	acetylesterase activity
FRC90_07465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FRC90_07470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FRC90_07485	COG0084	hydrolase, TatD family'
FRC90_07495	COG1132	(ABC) transporter
FRC90_07500	COG0823	Involved in the tonB-independent uptake of proteins
FRC90_07505	COG2885	chlorophyll binding
FRC90_07515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FRC90_07535	COG2423	ornithine cyclodeaminase activity
FRC90_07605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_07605	COG2010	Cytochrome c
FRC90_07615	COG0779	Required for maturation of 30S ribosomal subunits
FRC90_07620	COG0195	Participates in both transcription termination and antitermination
FRC90_07625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FRC90_07630	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FRC90_07635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FRC90_07645	COG1253	flavin adenine dinucleotide binding
FRC90_07650	COG1024	Enoyl-CoA hydratase
FRC90_07670	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FRC90_07680	COG2914	Belongs to the UPF0125 (RnfH) family
FRC90_07705	COG0519	Catalyzes the synthesis of GMP from XMP
FRC90_07705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FRC90_07750	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FRC90_07780	COG0583	DNA-binding transcription factor activity
FRC90_07790	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_07855	COG2226	methyltransferase
FRC90_07860	COG0492	ferredoxin-NADP+ reductase activity
FRC90_07875	COG1278	Cold shock
FRC90_07880	COG0494	nUDIX hydrolase
FRC90_07915	COG4774	siderophore transport
FRC90_07920	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FRC90_07930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FRC90_07940	COG0506	proline dehydrogenase activity
FRC90_07940	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FRC90_07940	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FRC90_07955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FRC90_07965	COG0670	Belongs to the BI1 family
FRC90_07970	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FRC90_08010	COG0405	Gamma-glutamyltransferase
FRC90_08015	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FRC90_08020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FRC90_08045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FRC90_08080	COG2212	antiporter activity
FRC90_08090	COG0651	ATP synthesis coupled electron transport
FRC90_08095	COG1006	Multisubunit Na H antiporter MnhC subunit
FRC90_08100	COG2111	Na H antiporter
FRC90_08100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FRC90_08105	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FRC90_08115	COG0776	regulation of translation
FRC90_08125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FRC90_08130	COG0287	Prephenate dehydrogenase
FRC90_08135	COG0077	Prephenate dehydratase
FRC90_08135	COG1605	Chorismate mutase
FRC90_08140	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FRC90_08155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC90_08275	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FRC90_08285	COG4166	transmembrane transport
FRC90_08290	COG4174	ABC transporter (Permease)
FRC90_08295	COG4239	(ABC) transporter, permease
FRC90_08300	COG4172	Belongs to the ABC transporter superfamily
FRC90_08305	COG5001	Diguanylate cyclase
FRC90_08305	COG5002	protein histidine kinase activity
FRC90_08305	COG3447	MASE1 domain protein
FRC90_08310	COG0628	permease
FRC90_08315	COG0567	Dehydrogenase, E1 component
FRC90_08320	COG0508	dehydrogenase complex catalyzes the overall conversion of
FRC90_08325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FRC90_08330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FRC90_08345	COG1199	ATP-dependent helicase activity
FRC90_08360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FRC90_08365	COG0542	response to heat
FRC90_08370	COG2951	lytic endotransglycosylase activity
FRC90_08375	COG2925	Exonuclease
FRC90_08385	COG3284	Transcriptional regulator
FRC90_08405	COG1012	belongs to the aldehyde dehydrogenase family
FRC90_08410	COG0484	heat shock protein binding
FRC90_08445	COG0402	S-adenosylhomocysteine deaminase activity
FRC90_08465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FRC90_08480	COG0625	glutathione transferase activity
FRC90_08505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FRC90_08510	COG0277	FAD linked oxidase domain protein
FRC90_08530	COG0433	COG0433 Predicted ATPase
FRC90_08535	COG0217	transcriptional regulatory protein
FRC90_08540	COG0151	Belongs to the GarS family
FRC90_08545	COG0408	coproporphyrinogen oxidase activity
FRC90_08550	COG0799	negative regulation of ribosome biogenesis
FRC90_08555	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FRC90_08565	COG0424	maF-like protein
FRC90_08570	COG1530	ribonuclease E activity
FRC90_08625	COG3593	DNA synthesis involved in DNA repair
FRC90_08640	COG2205	protein histidine kinase activity
FRC90_08645	COG0596	Alpha beta hydrolase
FRC90_08660	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_08670	COG1024	Enoyl-CoA hydratase
FRC90_08675	COG1960	acyl-CoA dehydrogenase activity
FRC90_08685	COG0683	leucine binding
FRC90_08720	COG0436	Aminotransferase
FRC90_08725	COG0583	DNA-binding transcription factor activity
FRC90_08745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FRC90_08785	COG0589	response to stress
FRC90_08805	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_08810	COG0564	pseudouridine synthase activity
FRC90_08820	COG0545	Peptidyl-prolyl cis-trans isomerase
FRC90_08825	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FRC90_08825	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FRC90_08830	COG0509	glycine decarboxylation via glycine cleavage system
FRC90_08835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FRC90_08850	COG4120	Belongs to the binding-protein-dependent transport system permease family
FRC90_08870	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_08905	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FRC90_08915	COG1252	NADH dehydrogenase
FRC90_08940	COG0835	chemotaxis
FRC90_08945	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_08955	COG0583	DNA-binding transcription factor activity
FRC90_08970	COG0347	Belongs to the P(II) protein family
FRC90_08980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FRC90_09000	COG1595	DNA-templated transcription, initiation
FRC90_09005	COG0028	Belongs to the TPP enzyme family
FRC90_09010	COG0440	acetolactate synthase activity
FRC90_09015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FRC90_09020	COG1183	phosphatidylcholine synthase activity
FRC90_09025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC90_09035	COG1414	Transcriptional regulator
FRC90_09040	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FRC90_09045	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FRC90_09060	COG2832	Protein of unknown function (DUF454)
FRC90_09065	COG0242	peptide deformylase activity
FRC90_09070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FRC90_09075	COG0024	Methionine aminopeptidase
FRC90_09080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FRC90_09080	COG0047	phosphoribosylformylglycinamidine synthase activity
FRC90_09095	COG5001	Diguanylate cyclase
FRC90_09095	COG3300	MHYT domain
FRC90_09100	COG2354	Protein conserved in bacteria
FRC90_09105	COG3047	cAMP biosynthetic process
FRC90_09120	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FRC90_09125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FRC90_09135	COG0823	Involved in the tonB-independent uptake of proteins
FRC90_09135	COG1506	peptidase
FRC90_09135	COG4946	Tricorn protease homolog
FRC90_09145	COG0826	peptidase U32
FRC90_09170	COG1619	proteins homologs of microcin C7 resistance protein MccF
FRC90_09185	COG1960	acyl-CoA dehydrogenase activity
FRC90_09200	COG1024	Enoyl-CoA hydratase
FRC90_09205	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC90_09220	COG2022	thiamine diphosphate biosynthetic process
FRC90_09235	COG0351	phosphomethylpyrimidine kinase
FRC90_09290	COG0492	ferredoxin-NADP+ reductase activity
FRC90_09295	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FRC90_09300	COG2895	sulfate adenylyltransferase (ATP) activity
FRC90_09300	COG0529	Catalyzes the synthesis of activated sulfate
FRC90_09305	COG0175	sulfate reduction
FRC90_09320	COG0730	response to heat
FRC90_09340	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FRC90_09340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_09345	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FRC90_09355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FRC90_09365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FRC90_09375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_09380	COG1116	anion transmembrane transporter activity
FRC90_09390	COG0583	DNA-binding transcription factor activity
FRC90_09410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FRC90_09420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FRC90_09425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC90_09435	COG0583	DNA-binding transcription factor activity
FRC90_09440	COG1741	Belongs to the pirin family
FRC90_09450	COG1741	Belongs to the pirin family
FRC90_09455	COG1054	Belongs to the UPF0176 family
FRC90_09495	COG4181	ATPase activity
FRC90_09500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FRC90_09505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FRC90_09510	COG0667	Aldo Keto reductase
FRC90_09525	COG0642	Histidine kinase
FRC90_09535	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_09585	COG5002	protein histidine kinase activity
FRC90_09590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FRC90_09595	COG1011	Hydrolase
FRC90_09610	COG0517	IMP dehydrogenase activity
FRC90_09610	COG1125	glycine betaine transport
FRC90_09615	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FRC90_09625	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FRC90_09630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FRC90_09635	COG0741	lytic transglycosylase activity
FRC90_09660	COG0557	exoribonuclease II activity
FRC90_09665	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_09675	COG0297	glycogen (starch) synthase activity
FRC90_09695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FRC90_09715	COG0784	Response regulator, receiver
FRC90_09715	COG4191	Histidine kinase
FRC90_09720	COG2205	protein histidine kinase activity
FRC90_09725	COG2205	protein histidine kinase activity
FRC90_09735	COG2172	sigma factor antagonist activity
FRC90_09740	COG1366	Belongs to the anti-sigma-factor antagonist family
FRC90_09745	COG1366	Belongs to the anti-sigma-factor antagonist family
FRC90_09755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_09765	COG2188	Transcriptional regulator
FRC90_09770	COG2986	histidine ammonia-lyase
FRC90_09775	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FRC90_09790	COG1228	amidohydrolase
FRC90_09820	COG0688	phosphatidylethanolamine metabolic process
FRC90_09825	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FRC90_10000	COG4695	Portal protein
FRC90_10005	COG0740	serine-type endopeptidase activity
FRC90_10055	COG1196	nuclear chromosome segregation
FRC90_10125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC90_10135	COG2917	probably involved in intracellular septation
FRC90_10140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FRC90_10145	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FRC90_10150	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_10160	COG0559	Belongs to the binding-protein-dependent transport system permease family
FRC90_10170	COG0411	ABC transporter
FRC90_10195	COG3706	GGDEF domain
FRC90_10210	COG1024	Enoyl-CoA hydratase
FRC90_10210	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC90_10215	COG0183	Belongs to the thiolase family
FRC90_10220	COG2050	protein possibly involved in aromatic compounds catabolism
FRC90_10225	COG1960	acyl-CoA dehydrogenase activity
FRC90_10245	COG2130	NADP-dependent
FRC90_10250	COG2153	protein acetylation
FRC90_10270	COG1840	ABC-type Fe3 transport system, periplasmic component
FRC90_10280	COG0697	spore germination
FRC90_10285	COG1522	sequence-specific DNA binding
FRC90_10300	COG2224	Isocitrate lyase
FRC90_10305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FRC90_10310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FRC90_10315	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FRC90_10320	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FRC90_10325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FRC90_10330	COG0072	phenylalanine-tRNA ligase activity
FRC90_10330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC90_10335	COG0776	regulation of translation
FRC90_10340	COG0789	Transcriptional regulator
FRC90_10365	COG1132	(ABC) transporter
FRC90_10370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FRC90_10380	COG1742	UPF0060 membrane protein
FRC90_10400	COG1196	nuclear chromosome segregation
FRC90_10410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FRC90_10480	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FRC90_10505	COG3048	D-serine ammonia-lyase activity
FRC90_10510	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_10515	COG0154	amidase activity
FRC90_10535	COG1739	Uncharacterized protein family UPF0029
FRC90_10550	COG0840	transmembrane signaling receptor activity
FRC90_10565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_10575	COG0556	nucleotide-excision repair
FRC90_10580	COG1959	2 iron, 2 sulfur cluster binding
FRC90_10585	COG1104	cysteine desulfurase activity
FRC90_10590	COG0822	iron-sulfur transferase activity
FRC90_10600	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FRC90_10605	COG0443	Heat shock 70 kDa protein
FRC90_10610	COG0633	Ferredoxin
FRC90_10635	COG0579	oxidoreductase
FRC90_10655	COG0167	dihydroorotate dehydrogenase activity
FRC90_10660	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FRC90_10675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FRC90_10680	COG4566	intracellular signal transduction
FRC90_10690	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FRC90_10695	COG0508	dehydrogenase complex catalyzes the overall conversion of
FRC90_10700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FRC90_10725	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FRC90_10730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC90_10740	COG0515	serine threonine protein kinase
FRC90_10770	COG3243	poly(R)-hydroxyalkanoic acid synthase
FRC90_10775	COG0183	Belongs to the thiolase family
FRC90_10780	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_10785	COG0488	(ABC) transporter
FRC90_10790	COG2890	protein-(glutamine-N5) methyltransferase activity
FRC90_10795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FRC90_10805	COG2171	N-acyltransferase activity
FRC90_10815	COG0840	transmembrane signaling receptor activity
FRC90_10820	COG2878	Part of a membrane complex involved in electron transport
FRC90_10840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC90_10865	COG3039	Transposase
FRC90_10880	COG0840	transmembrane signaling receptor activity
FRC90_10945	COG1802	Transcriptional regulator
FRC90_10950	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FRC90_10950	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FRC90_10960	COG1703	isobutyryl-CoA mutase activity
FRC90_10965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FRC90_10975	COG4770	biotin carboxylase activity
FRC90_10995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FRC90_11045	COG5002	protein histidine kinase activity
FRC90_11060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC90_11075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FRC90_11080	COG0583	DNA-binding transcription factor activity
FRC90_11085	COG2814	Major facilitator Superfamily
FRC90_11095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FRC90_11100	COG2011	ABC-type metal ion transport system permease component
FRC90_11120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FRC90_11140	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FRC90_11145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FRC90_11150	COG4208	sulfate ABC transporter
FRC90_11155	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FRC90_11160	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FRC90_11165	COG1054	Belongs to the UPF0176 family
FRC90_11180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FRC90_11180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FRC90_11185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_11195	COG1643	Atp-dependent helicase
FRC90_11205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FRC90_11210	COG0252	asparaginase activity
FRC90_11220	COG0563	adenylate kinase activity
FRC90_11225	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FRC90_11230	COG2835	tetraacyldisaccharide 4'-kinase activity
FRC90_11235	COG1663	tetraacyldisaccharide 4'-kinase activity
FRC90_11240	COG0848	biopolymer transport protein
FRC90_11245	COG0811	peptide transport
FRC90_11250	COG1570	exodeoxyribonuclease VII activity
FRC90_11255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FRC90_11285	COG0625	glutathione transferase activity
FRC90_11290	COG1942	4-Oxalocrotonate Tautomerase
FRC90_11305	COG2814	Major facilitator Superfamily
FRC90_11310	COG0789	Transcriptional regulator
FRC90_11350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC90_11355	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_11365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FRC90_11375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_11390	COG2721	sulfolactate sulfo-lyase activity
FRC90_11405	COG4772	TonB-dependent receptor
FRC90_11410	COG2032	superoxide dismutase activity
FRC90_11425	COG1960	acyl-CoA dehydrogenase activity
FRC90_11450	COG1113	amino acid transport
FRC90_11460	COG0505	Belongs to the CarA family
FRC90_11465	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FRC90_11470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FRC90_11485	COG1534	Rna-binding protein
FRC90_11490	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FRC90_11495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FRC90_11505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FRC90_11535	COG0248	Ppx GppA phosphatase
FRC90_11540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FRC90_11545	COG0573	inorganic phosphate transmembrane transporter activity
FRC90_11550	COG0581	inorganic phosphate transmembrane transporter activity
FRC90_11555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FRC90_11560	COG0704	Plays a role in the regulation of phosphate uptake
FRC90_11575	COG0534	Mate efflux family protein
FRC90_11585	COG0254	rRNA binding
FRC90_11590	COG0420	3'-5' exonuclease activity
FRC90_11595	COG0419	ATPase involved in DNA repair
FRC90_11600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FRC90_11615	COG1074	ATP-dependent DNA helicase activity
FRC90_11620	COG2081	HI0933 family
FRC90_11635	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FRC90_11640	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FRC90_11645	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FRC90_11665	COG1388	LysM domain
FRC90_11665	COG0741	lytic transglycosylase activity
FRC90_11670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FRC90_11675	COG2226	methyltransferase
FRC90_11680	COG0328	RNA-DNA hybrid ribonuclease activity
FRC90_11695	COG0303	'Molybdopterin
FRC90_11705	COG0746	molybdenum cofactor guanylyltransferase activity
FRC90_11710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FRC90_11735	COG1012	belongs to the aldehyde dehydrogenase family
FRC90_11760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FRC90_11775	COG0587	DNA-directed DNA polymerase activity
FRC90_11780	COG2982	Protein involved in outer membrane biogenesis
FRC90_11785	COG0564	pseudouridine synthase activity
FRC90_11800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FRC90_11810	COG0431	NADPH-dependent FMN reductase
FRC90_11815	COG0583	DNA-binding transcription factor activity
FRC90_11855	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_11860	COG0346	lactoylglutathione lyase activity
FRC90_11870	COG0800	Aldolase
FRC90_11880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_11885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC90_11890	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC90_11895	COG3265	gluconokinase activity
FRC90_11900	COG1609	Transcriptional regulator
FRC90_11925	COG0259	pyridoxamine-phosphate oxidase activity
FRC90_11940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_11945	COG4771	TonB-dependent receptor
FRC90_11970	COG1136	(ABC) transporter
FRC90_11980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FRC90_11985	COG1309	transcriptional regulator
FRC90_12005	COG1042	CoA-binding domain protein
FRC90_12005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FRC90_12005	COG0045	succinate-CoA ligase (ADP-forming) activity
FRC90_12055	COG2133	pyrroloquinoline quinone binding
FRC90_12060	COG0791	NLP P60 protein
FRC90_12105	COG3209	COG3209 Rhs family protein
FRC90_12165	COG0527	aspartate kinase activity
FRC90_12170	COG0037	tRNA processing
FRC90_12185	COG0215	cysteine-tRNA ligase activity
FRC90_12240	COG1522	sequence-specific DNA binding
FRC90_12260	COG3384	dioxygenase
FRC90_12275	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FRC90_12285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC90_12300	COG1309	transcriptional regulator
FRC90_12340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC90_12370	COG0840	transmembrane signaling receptor activity
FRC90_12400	COG0564	pseudouridine synthase activity
FRC90_12405	COG1285	pathogenesis
FRC90_12420	COG2814	Major facilitator Superfamily
FRC90_12440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FRC90_12455	COG5002	protein histidine kinase activity
FRC90_12470	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FRC90_12480	COG2918	glutathione biosynthetic process
FRC90_12490	COG3386	PFAM SMP-30 Gluconolaconase
FRC90_12510	COG1879	ABC-type sugar transport system periplasmic component
FRC90_12515	COG4213	ABC transporter substrate-binding protein
FRC90_12525	COG4214	carbohydrate transport
FRC90_12535	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC90_12540	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC90_12560	COG3734	2-keto-3-deoxy-galactonokinase
FRC90_12565	COG0800	Aldolase
FRC90_12570	COG4948	Mandelate Racemase Muconate Lactonizing
FRC90_12575	COG1289	transmembrane transporter activity
FRC90_12600	COG0745	RESPONSE REGULATOR receiver
FRC90_12610	COG2202	Pas domain
FRC90_12610	COG2205	protein histidine kinase activity
FRC90_12620	COG0633	Ferredoxin
FRC90_12635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FRC90_12640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC90_12645	COG0436	Aminotransferase
FRC90_12650	COG0824	Thioesterase
FRC90_12670	COG0477	Major facilitator Superfamily
FRC90_12675	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FRC90_12680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FRC90_12685	COG1845	cytochrome c oxidase, subunit III
FRC90_12690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FRC90_12720	COG0826	peptidase U32
FRC90_12735	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FRC90_12740	COG1049	propionate catabolic process, 2-methylcitrate cycle
FRC90_12755	COG4106	trans-aconitate 2-methyltransferase activity
FRC90_12760	COG0039	L-malate dehydrogenase activity
FRC90_12765	COG2188	Transcriptional regulator
FRC90_12780	COG1053	succinate dehydrogenase
FRC90_12785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FRC90_12790	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FRC90_12795	COG0372	Belongs to the citrate synthase family
FRC90_12805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FRC90_12810	COG4977	sequence-specific DNA binding
FRC90_12820	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FRC90_12825	COG2194	sulfuric ester hydrolase activity
FRC90_12835	COG0473	3-isopropylmalate dehydrogenase activity
FRC90_12845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC90_12850	COG0601	transmembrane transport
FRC90_12860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_12880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC90_12890	COG1522	sequence-specific DNA binding
FRC90_12895	COG1473	amidohydrolase
FRC90_12940	COG1960	acyl-CoA dehydrogenase activity
FRC90_12955	COG1511	domain protein
FRC90_12955	COG3264	Mechanosensitive ion channel
FRC90_12970	COG1024	Enoyl-CoA hydratase
FRC90_12975	COG0123	including yeast histone deacetylase and acetoin utilization protein
FRC90_12980	COG0714	Associated with various cellular activities
FRC90_12995	COG2951	lytic endotransglycosylase activity
FRC90_13025	COG0683	leucine binding
FRC90_13040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FRC90_13045	COG0683	leucine binding
FRC90_13065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FRC90_13070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_13075	COG1116	anion transmembrane transporter activity
FRC90_13080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FRC90_13095	COG0724	RNA recognition motif
FRC90_13105	COG0626	cystathionine gamma-synthase activity
FRC90_13120	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FRC90_13145	COG0194	GDP metabolic process
FRC90_13150	COG3958	Transketolase
FRC90_13155	COG3959	Transketolase, thiamine diphosphate binding domain
FRC90_13160	COG2223	nitrite transmembrane transporter activity
FRC90_13175	COG0745	RESPONSE REGULATOR receiver
FRC90_13185	COG0840	transmembrane signaling receptor activity
FRC90_13190	COG0643	Histidine kinase
FRC90_13190	COG2198	Histidine kinase
FRC90_13210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FRC90_13215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FRC90_13220	COG0516	GMP reductase activity
FRC90_13220	COG0517	IMP dehydrogenase activity
FRC90_13225	COG0840	transmembrane signaling receptor activity
FRC90_13235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC90_13250	COG0840	transmembrane signaling receptor activity
FRC90_13255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FRC90_13265	COG0243	molybdopterin cofactor binding
FRC90_13270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FRC90_13280	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FRC90_13280	COG5297	Belongs to the glycosyl hydrolase family 6
FRC90_13285	COG1607	acyl-coa hydrolase
FRC90_13290	COG0288	reversible hydration of carbon dioxide
FRC90_13305	COG2081	HI0933 family
FRC90_13310	COG0640	Transcriptional regulator
FRC90_13330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FRC90_13335	COG1610	YqeY-like protein
FRC90_13340	COG0625	glutathione transferase activity
FRC90_13350	COG0583	DNA-binding transcription factor activity
FRC90_13355	COG0473	3-isopropylmalate dehydrogenase activity
FRC90_13360	COG1752	Esterase of the alpha-beta hydrolase superfamily
FRC90_13365	COG0477	Major facilitator Superfamily
FRC90_13380	COG2721	sulfolactate sulfo-lyase activity
FRC90_13395	COG0312	modulator of DNA gyrase
FRC90_13400	COG3028	Belongs to the UPF0307 family
FRC90_13405	COG0521	Mo-molybdopterin cofactor biosynthetic process
FRC90_13410	COG1045	serine acetyltransferase
FRC90_13420	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FRC90_13425	COG4555	ABC transporter
FRC90_13440	COG0483	inositol monophosphate 1-phosphatase activity
FRC90_13455	COG1132	(ABC) transporter
FRC90_13465	COG3437	response regulator, receiver
FRC90_13470	COG0784	Response regulator, receiver
FRC90_13470	COG2205	protein histidine kinase activity
FRC90_13470	COG5002	protein histidine kinase activity
FRC90_13525	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FRC90_13530	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FRC90_13545	COG3209	COG3209 Rhs family protein
FRC90_13570	COG3447	MASE1 domain protein
FRC90_13570	COG5002	protein histidine kinase activity
FRC90_13570	COG5001	Diguanylate cyclase
FRC90_13575	COG1968	undecaprenyl-diphosphatase activity
FRC90_13605	COG3275	phosphorelay sensor kinase activity
FRC90_13610	COG3279	Response regulator of the LytR AlgR family
FRC90_13615	COG1280	lysine exporter protein (LysE YggA)
FRC90_13625	COG4133	protoheme IX ABC transporter activity
FRC90_13635	COG2005	Transcriptional regulator
FRC90_13635	COG3585	molybdate ion transport
FRC90_13655	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FRC90_13660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FRC90_13665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FRC90_13670	COG0366	Alpha amylase catalytic
FRC90_13675	COG0366	Alpha amylase catalytic
FRC90_13680	COG0668	transmembrane transport
FRC90_13700	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FRC90_13705	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FRC90_13710	COG0142	geranyltranstransferase activity
FRC90_13715	COG1722	exodeoxyribonuclease VII activity
FRC90_13770	COG0628	permease
FRC90_13775	COG1289	transmembrane transporter activity
FRC90_13780	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FRC90_13785	COG0181	hydroxymethylbilane synthase activity
FRC90_13805	COG0488	(ABC) transporter
FRC90_13815	COG0501	Belongs to the peptidase M48B family
FRC90_13820	COG0525	valine-tRNA ligase activity
FRC90_13825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FRC90_13835	COG0425	Belongs to the sulfur carrier protein TusA family
FRC90_13840	COG2816	NAD+ diphosphatase activity
FRC90_13880	COG0583	DNA-binding transcription factor activity
FRC90_13885	COG1960	acyl-CoA dehydrogenase activity
FRC90_13890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_13930	COG0617	tRNA 3'-terminal CCA addition
FRC90_13940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FRC90_13945	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FRC90_13975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FRC90_13995	COG0840	transmembrane signaling receptor activity
FRC90_14000	COG1304	FMN binding
FRC90_14010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC90_14015	COG0840	transmembrane signaling receptor activity
FRC90_14050	COG0165	Argininosuccinate lyase
FRC90_14055	COG3275	phosphorelay sensor kinase activity
FRC90_14065	COG0165	Argininosuccinate lyase
FRC90_14075	COG0412	Dienelactone hydrolase
FRC90_14105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_14110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_14150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FRC90_14235	COG0516	GMP reductase activity
FRC90_14295	COG2204	response regulator
FRC90_14300	COG5002	protein histidine kinase activity
FRC90_14305	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FRC90_14320	COG2814	Major facilitator Superfamily
FRC90_14325	COG5002	protein histidine kinase activity
FRC90_14325	COG5001	Diguanylate cyclase
FRC90_14325	COG3447	MASE1 domain protein
FRC90_14330	COG0513	Belongs to the DEAD box helicase family
FRC90_14335	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FRC90_14345	COG2154	pterin-4-alpha-carbinolamine dehydratase
FRC90_14350	COG1162	GTPase activity
FRC90_14355	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FRC90_14365	COG0335	large ribosomal subunit rRNA binding
FRC90_14370	COG0336	Belongs to the RNA methyltransferase TrmD family
FRC90_14375	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FRC90_14380	COG0228	four-way junction DNA binding
FRC90_14395	COG0306	phosphate transporter
FRC90_14400	COG1392	Phosphate transport regulator
FRC90_14405	COG2885	chlorophyll binding
FRC90_14405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FRC90_14425	COG0559	Belongs to the binding-protein-dependent transport system permease family
FRC90_14430	COG0840	transmembrane signaling receptor activity
FRC90_14435	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FRC90_14440	COG1573	uracil-dna glycosylase
FRC90_14450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FRC90_14455	COG1674	ftsk spoiiie
FRC90_14460	COG0492	ferredoxin-NADP+ reductase activity
FRC90_14465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FRC90_14470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FRC90_14475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC90_14490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FRC90_14490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC90_14495	COG3866	Pectate lyase
FRC90_14510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FRC90_14515	COG3132	Protein of unknown function, DUF480
FRC90_14520	COG1960	acyl-CoA dehydrogenase activity
FRC90_14540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC90_14545	COG0840	transmembrane signaling receptor activity
FRC90_14550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC90_14560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_14570	COG0196	riboflavin kinase activity
FRC90_14580	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FRC90_14590	COG1609	Transcriptional regulator
FRC90_14600	COG4149	molybdate abc transporter
FRC90_14605	COG1177	transmembrane transport
FRC90_14610	COG3842	ATPase activity
FRC90_14615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FRC90_14625	COG1283	sodium-dependent phosphate transmembrane transporter activity
FRC90_14640	COG0583	DNA-binding transcription factor activity
FRC90_14670	COG0697	spore germination
FRC90_14700	COG3209	COG3209 Rhs family protein
FRC90_14710	COG3209	COG3209 Rhs family protein
FRC90_14765	COG2814	Major facilitator Superfamily
FRC90_14820	COG1301	dicarboxylic acid transport
FRC90_14825	COG5599	Phosphatase
FRC90_14850	COG3038	cytochrome b561
FRC90_14865	COG4770	biotin carboxylase activity
FRC90_14870	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FRC90_14875	COG4336	lyase activity
FRC90_14880	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FRC90_14885	COG2814	Major facilitator Superfamily
FRC90_14905	COG2205	protein histidine kinase activity
FRC90_14910	COG1304	FMN binding
FRC90_14935	COG5001	Diguanylate cyclase
FRC90_14950	COG0831	urea catabolic process
FRC90_14960	COG0832	Belongs to the urease beta subunit family
FRC90_14965	COG0804	urea catabolic process
FRC90_14975	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FRC90_14980	COG0830	nickel cation binding
FRC90_14985	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FRC90_15000	COG0464	growth
FRC90_15025	COG2249	NAD(P)H dehydrogenase (quinone) activity
FRC90_15030	COG5000	phosphorelay sensor kinase activity
FRC90_15030	COG5002	protein histidine kinase activity
FRC90_15070	COG4968	Prepilin-type N-terminal cleavage methylation domain
FRC90_15075	COG4968	Prepilin-type N-terminal cleavage methylation domain
FRC90_15100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FRC90_15100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FRC90_15145	COG0784	Response regulator, receiver
FRC90_15145	COG4191	Histidine kinase
FRC90_15150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC90_15175	COG1595	DNA-templated transcription, initiation
FRC90_15190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC90_15195	COG4221	oxidoreductase activity
FRC90_15210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FRC90_15215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FRC90_15235	COG1561	YicC-like family, N-terminal region
FRC90_15240	COG0194	GDP metabolic process
FRC90_15245	COG1758	RNA polymerase activity
FRC90_15250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FRC90_15280	COG3693	PFAM glycoside hydrolase, family 10
FRC90_15285	COG2197	response regulator
FRC90_15295	COG1420	regulation of RNA biosynthetic process
FRC90_15300	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FRC90_15305	COG0497	DNA recombination
FRC90_15310	COG1660	Displays ATPase and GTPase activities
FRC90_15315	COG1194	a g-specific adenine glycosylase
FRC90_15325	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FRC90_15340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FRC90_15350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FRC90_15355	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FRC90_15360	COG0193	aminoacyl-tRNA hydrolase activity
FRC90_15365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FRC90_15375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC90_15380	COG0444	Belongs to the ABC transporter superfamily
FRC90_15385	COG4608	Belongs to the ABC transporter superfamily
FRC90_15395	COG0747	negative chemotaxis
FRC90_15425	COG1609	Transcriptional regulator
FRC90_15455	COG0302	gtp cyclohydrolase
FRC90_15460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC90_15470	COG0745	RESPONSE REGULATOR receiver
FRC90_15475	COG0494	nUDIX hydrolase
FRC90_15485	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FRC90_15505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FRC90_15520	COG2226	methyltransferase
FRC90_15545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC90_15550	COG1653	transport
FRC90_15555	COG1175	transmembrane transport
FRC90_15560	COG0395	ABC-type sugar transport system, permease component
FRC90_15565	COG3842	ATPase activity
FRC90_15575	COG0584	glycerophosphoryl diester phosphodiesterase
FRC90_15580	COG1511	domain protein
FRC90_15580	COG3264	Mechanosensitive ion channel
FRC90_15595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FRC90_15615	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FRC90_15620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FRC90_15630	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FRC90_15635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FRC90_15640	COG1253	flavin adenine dinucleotide binding
FRC90_15650	COG0442	prolyl-tRNA aminoacylation
FRC90_15655	COG0494	nUDIX hydrolase
FRC90_15660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FRC90_15665	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FRC90_15670	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FRC90_15675	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FRC90_15680	COG0142	geranyltranstransferase activity
FRC90_15690	COG1473	amidohydrolase
FRC90_15700	COG0583	DNA-binding transcription factor activity
FRC90_15720	COG0237	dephospho-CoA kinase activity
FRC90_15725	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FRC90_15730	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FRC90_15735	COG0494	nUDIX hydrolase
FRC90_15745	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FRC90_15750	COG0653	protein targeting
FRC90_15755	COG0739	heme binding
FRC90_15770	COG2969	positive regulation of protein catabolic process
FRC90_15775	COG0625	glutathione transferase activity
FRC90_15780	COG2857	Cytochrome c1
FRC90_15785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FRC90_15790	COG0723	plastoquinol--plastocyanin reductase activity
FRC90_15795	COG1970	mechanosensitive ion channel activity
FRC90_15800	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FRC90_15805	COG1136	(ABC) transporter
FRC90_15815	COG4591	ABC-type transport system involved in lipoprotein release permease component
FRC90_15825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FRC90_15840	COG0738	Major facilitator superfamily
FRC90_15845	COG0613	PHP domain protein
FRC90_15850	COG0009	L-threonylcarbamoyladenylate synthase
FRC90_15860	COG1994	Peptidase M50
FRC90_15865	COG0180	Tryptophanyl-tRNA synthetase
FRC90_15870	COG3209	COG3209 Rhs family protein
FRC90_15935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FRC90_15980	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FRC90_15990	COG4774	siderophore transport
FRC90_15995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FRC90_16050	COG0443	Heat shock 70 kDa protein
FRC90_16100	COG0038	chloride channel
FRC90_16135	COG3209	COG3209 Rhs family protein
FRC90_16145	COG0612	Peptidase, M16
FRC90_16150	COG0765	amino acid transport
FRC90_16155	COG0765	amino acid transport
FRC90_16160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_16175	COG0129	dihydroxy-acid dehydratase activity
FRC90_16220	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FRC90_16225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC90_16230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FRC90_16230	COG0617	tRNA 3'-terminal CCA addition
FRC90_16230	COG0517	IMP dehydrogenase activity
FRC90_16235	COG1253	flavin adenine dinucleotide binding
FRC90_16240	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FRC90_16245	COG1047	Peptidyl-prolyl cis-trans
FRC90_16250	COG2003	Belongs to the UPF0758 family
FRC90_16270	COG1193	negative regulation of DNA recombination
FRC90_16295	COG0737	Belongs to the 5'-nucleotidase family
FRC90_16345	COG2801	Transposase and inactivated derivatives
FRC90_16375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FRC90_16390	COG0534	Mate efflux family protein
FRC90_16395	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_16420	COG2771	luxR family
FRC90_16425	COG3916	Acyl-homoserine-lactone synthase
FRC90_16435	COG1802	Transcriptional regulator
FRC90_16445	COG0154	amidase activity
FRC90_16490	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FRC90_16500	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FRC90_16505	COG0243	molybdopterin cofactor binding
FRC90_16510	COG0840	transmembrane signaling receptor activity
FRC90_16515	COG2223	nitrite transmembrane transporter activity
FRC90_16520	COG0489	protein tyrosine kinase activity
FRC90_16535	COG0028	Belongs to the TPP enzyme family
FRC90_16540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC90_16540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC90_16570	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FRC90_16580	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FRC90_16585	COG0156	8-amino-7-oxononanoate synthase activity
FRC90_16590	COG0602	queuosine metabolic process
FRC90_16595	COG0720	synthase
FRC90_16620	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FRC90_16630	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FRC90_16635	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FRC90_16640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FRC90_16645	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FRC90_16655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FRC90_16660	COG0588	phosphoglycerate mutase activity
FRC90_16665	COG0793	Belongs to the peptidase S41A family
FRC90_16670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FRC90_16680	COG2197	response regulator
FRC90_16690	COG5487	UPF0391 membrane protein
FRC90_16715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FRC90_16720	COG0742	ribosomal rna small subunit methyltransferase
FRC90_16725	COG0612	Peptidase, M16
FRC90_16730	COG0612	Peptidase, M16
FRC90_16740	COG0179	Fumarylacetoacetate (FAA) hydrolase
FRC90_16765	COG0840	transmembrane signaling receptor activity
FRC90_16770	COG4977	sequence-specific DNA binding
FRC90_16785	COG0534	Mate efflux family protein
FRC90_16815	COG3842	ATPase activity
FRC90_16825	COG0583	DNA-binding transcription factor activity
FRC90_16835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FRC90_16855	COG1999	signal sequence binding
FRC90_16860	COG0109	protoheme IX farnesyltransferase activity
FRC90_16865	COG1612	heme a metabolic process
FRC90_16910	COG2226	methyltransferase
FRC90_16915	COG1040	competence protein
FRC90_16920	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FRC90_16925	COG0583	DNA-binding transcription factor activity
FRC90_16940	COG1192	Involved in chromosome partitioning
FRC90_16945	COG1280	lysine exporter protein (LysE YggA)
FRC90_16955	COG4774	siderophore transport
FRC90_16975	COG3038	cytochrome b561
FRC90_16980	COG1846	Transcriptional regulator
FRC90_16985	COG0840	transmembrane signaling receptor activity
FRC90_16990	COG0477	Major facilitator Superfamily
FRC90_16995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_16995	COG2010	Cytochrome c
FRC90_17000	COG2080	2 iron, 2 sulfur cluster binding
FRC90_17010	COG3473	Maleate cis-trans isomerase
FRC90_17015	COG0596	Alpha beta hydrolase
FRC90_17020	COG2309	aminopeptidase activity
FRC90_17025	COG1335	isochorismatase
FRC90_17030	COG2010	Cytochrome c
FRC90_17030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_17050	COG3387	PFAM Glycoside hydrolase 15-related
FRC90_17055	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_17065	COG2031	fatty acid transporter
FRC90_17085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC90_17090	COG0183	Belongs to the thiolase family
FRC90_17095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FRC90_17105	COG1414	Transcriptional regulator
FRC90_17135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FRC90_17205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC90_17220	COG0346	lactoylglutathione lyase activity
FRC90_17250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FRC90_17280	COG1132	(ABC) transporter
FRC90_17285	COG0189	ligase activity
FRC90_17285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC90_17290	COG1181	Belongs to the D-alanine--D-alanine ligase family
FRC90_17290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC90_17295	COG3045	CreA protein
FRC90_17310	COG3145	DNA-N1-methyladenine dioxygenase activity
FRC90_17325	COG0753	catalase activity
FRC90_17330	COG0745	RESPONSE REGULATOR receiver
FRC90_17335	COG0784	Response regulator, receiver
FRC90_17335	COG5002	protein histidine kinase activity
FRC90_17345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FRC90_17380	COG0601	transmembrane transport
FRC90_17385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC90_17395	COG0514	ATP-dependent DNA helicase (RecQ)
FRC90_17440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_17445	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FRC90_17450	COG2080	2 iron, 2 sulfur cluster binding
FRC90_17490	COG0737	Belongs to the 5'-nucleotidase family
FRC90_17495	COG0583	DNA-binding transcription factor activity
FRC90_17500	COG2855	membrane
FRC90_17510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FRC90_17535	COG2267	carboxylic ester hydrolase activity
FRC90_17545	COG3002	Belongs to the UPF0753 family
FRC90_17550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FRC90_17595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FRC90_17620	COG0583	DNA-binding transcription factor activity
FRC90_17625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FRC90_17635	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FRC90_17640	COG2814	Major facilitator Superfamily
FRC90_17645	COG0316	Belongs to the HesB IscA family
FRC90_17660	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FRC90_17665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FRC90_17670	COG0515	serine threonine protein kinase
FRC90_17670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FRC90_17675	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FRC90_17680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FRC90_17705	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FRC90_17725	COG2076	Multidrug Resistance protein
FRC90_17755	COG1126	abc transporter atp-binding protein
FRC90_17760	COG0765	amino acid transport
FRC90_17765	COG0765	amino acid transport
FRC90_17770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_17780	COG0583	DNA-binding transcription factor activity
FRC90_17785	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC90_17790	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC90_17790	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC90_17795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_17800	COG5265	(ABC) transporter
FRC90_17815	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_17820	COG1024	Enoyl-CoA hydratase
FRC90_17830	COG0183	Belongs to the thiolase family
FRC90_17840	COG1024	Enoyl-CoA hydratase
FRC90_17840	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC90_17850	COG1960	acyl-CoA dehydrogenase activity
FRC90_18090	COG1309	transcriptional regulator
FRC90_18100	COG0745	RESPONSE REGULATOR receiver
FRC90_18105	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FRC90_18145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC90_18160	COG1450	Type ii and iii secretion system protein
FRC90_18190	COG2165	general secretion pathway protein
FRC90_18195	COG4970	Tfp pilus assembly protein FimT
FRC90_18200	COG2165	general secretion pathway protein
FRC90_18205	COG1459	type II secretion system
FRC90_18210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FRC90_18250	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FRC90_18255	COG1652	LysM domain
FRC90_18275	COG0204	Acyl-transferase
FRC90_18280	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FRC90_18290	COG0751	glycine-tRNA ligase activity
FRC90_18295	COG0752	glycyl-tRNA synthetase alpha subunit
FRC90_18300	COG3258	Cytochrome c
FRC90_18310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FRC90_18325	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FRC90_18330	COG4535	Mg2 and Co2 transporter CorC
FRC90_18345	COG1522	sequence-specific DNA binding
FRC90_18350	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FRC90_18370	COG3186	Phenylalanine-4-hydroxylase
FRC90_18385	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_18395	COG1129	ABC transporter
FRC90_18400	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC90_18410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FRC90_18415	COG1869	D-ribose catabolic process
FRC90_18430	COG0739	heme binding
FRC90_18430	COG0741	lytic transglycosylase activity
FRC90_18430	COG1196	nuclear chromosome segregation
FRC90_18435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FRC90_18460	COG0617	tRNA 3'-terminal CCA addition
FRC90_18475	COG3387	PFAM Glycoside hydrolase 15-related
FRC90_18480	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FRC90_18500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_18515	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_18525	COG2879	small protein
FRC90_18530	COG1966	Carbon starvation protein
FRC90_18535	COG2197	response regulator
FRC90_18545	COG0037	tRNA processing
FRC90_18580	COG2255	four-way junction helicase activity
FRC90_18590	COG0632	four-way junction helicase activity
FRC90_18595	COG1702	phosphate starvation-inducible protein PhoH
FRC90_18615	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FRC90_18620	COG1490	D-aminoacyl-tRNA deacylase activity
FRC90_18625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FRC90_18630	COG0513	Belongs to the DEAD box helicase family
FRC90_18635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FRC90_18640	COG3706	GGDEF domain
FRC90_18655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FRC90_18655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FRC90_18665	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FRC90_18665	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FRC90_18685	COG0443	Heat shock 70 kDa protein
FRC90_18695	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FRC90_18700	COG1131	(ABC) transporter
FRC90_18705	COG0842	Transport permease protein
FRC90_18710	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC90_18720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC90_18740	COG0179	Fumarylacetoacetate (FAA) hydrolase
FRC90_18745	COG3971	2-oxopent-4-enoate hydratase activity
FRC90_18755	COG1846	Transcriptional regulator
FRC90_18760	COG1764	response to oxidative stress
FRC90_18770	COG0515	serine threonine protein kinase
FRC90_18770	COG2815	serine threonine protein kinase
FRC90_18850	COG0326	Molecular chaperone. Has ATPase activity
FRC90_18880	COG0840	transmembrane signaling receptor activity
FRC90_18900	COG3568	Endonuclease Exonuclease Phosphatase
FRC90_18905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC90_18910	COG0392	lysyltransferase activity
FRC90_18915	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FRC90_18925	COG0840	transmembrane signaling receptor activity
FRC90_18960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_18965	COG1024	Enoyl-CoA hydratase
FRC90_18970	COG1960	acyl-CoA dehydrogenase activity
FRC90_18975	COG1960	acyl-CoA dehydrogenase activity
FRC90_18980	COG1024	Enoyl-CoA hydratase
FRC90_18980	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC90_18985	COG0583	DNA-binding transcription factor activity
FRC90_18990	COG0501	Belongs to the peptidase M48B family
FRC90_19005	COG0418	dihydroorotase activity
FRC90_19010	COG2205	protein histidine kinase activity
FRC90_19015	COG0745	RESPONSE REGULATOR receiver
FRC90_19030	COG0577	efflux transmembrane transporter activity
FRC90_19030	COG1136	(ABC) transporter
FRC90_19060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FRC90_19125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FRC90_19140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FRC90_19175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC90_19190	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FRC90_19195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FRC90_19200	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_19220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FRC90_19225	COG2198	Histidine kinase
FRC90_19225	COG2205	protein histidine kinase activity
FRC90_19225	COG0784	Response regulator, receiver
FRC90_19230	COG3012	SEC-C Motif Domain Protein
FRC90_19245	COG1960	acyl-CoA dehydrogenase activity
FRC90_19260	COG0183	Belongs to the thiolase family
FRC90_19265	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FRC90_19270	COG0288	reversible hydration of carbon dioxide
FRC90_19275	COG1960	acyl-CoA dehydrogenase activity
FRC90_19285	COG0789	Transcriptional regulator
FRC90_19315	COG0488	(ABC) transporter
FRC90_19320	COG2201	protein-glutamate methylesterase activity
FRC90_19325	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FRC90_19330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FRC90_19335	COG0835	chemotaxis
FRC90_19340	COG0643	Histidine kinase
FRC90_19340	COG2198	Histidine kinase
FRC90_19345	COG0745	RESPONSE REGULATOR receiver
FRC90_19355	COG3851	Histidine kinase
FRC90_19360	COG2197	response regulator
FRC90_19370	COG1987	bacterial-type flagellum assembly
FRC90_19385	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FRC90_19395	COG1580	Controls the rotational direction of flagella during chemotaxis
FRC90_19425	COG1766	The M ring may be actively involved in energy transduction
FRC90_19430	COG1677	Flagellar hook-basal body complex protein FliE
FRC90_19465	COG4106	trans-aconitate 2-methyltransferase activity
FRC90_19475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_19480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FRC90_19485	COG0438	transferase activity, transferring glycosyl groups
FRC90_19485	COG1216	Glycosyl transferase, family 2
FRC90_19490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FRC90_19495	COG1360	Flagellar Motor Protein
FRC90_19500	COG0745	RESPONSE REGULATOR receiver
FRC90_19505	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FRC90_19510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FRC90_19550	COG1815	bacterial-type flagellum-dependent cell motility
FRC90_19555	COG1558	bacterial-type flagellum-dependent cell motility
FRC90_19560	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FRC90_19570	COG4787	bacterial-type flagellum-dependent cell motility
FRC90_19580	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FRC90_19590	COG1706	bacterial-type flagellum-dependent cell motility
FRC90_19595	COG1705	Flagellar rod assembly protein muramidase FlgJ
FRC90_19595	COG3951	Flagellar rod assembly protein muramidase FlgJ
FRC90_19605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FRC90_19625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC90_19635	COG0697	spore germination
FRC90_19640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC90_19645	COG0625	glutathione transferase activity
FRC90_19650	COG0384	phenazine biosynthesis protein PhzF
FRC90_19680	COG0840	transmembrane signaling receptor activity
FRC90_19725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FRC90_19755	COG0861	Integral membrane protein TerC family
FRC90_19760	COG0583	DNA-binding transcription factor activity
FRC90_19780	COG3119	arylsulfatase activity
FRC90_19795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FRC90_19805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FRC90_19825	COG0210	DNA helicase
FRC90_19850	COG0343	queuine tRNA-ribosyltransferase activity
FRC90_19880	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_19910	COG1522	sequence-specific DNA binding
FRC90_19915	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FRC90_19925	COG0840	transmembrane signaling receptor activity
FRC90_19965	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_19970	COG2072	flavoprotein involved in K transport
FRC90_19980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_20000	COG2365	Tyrosine phosphatase family
FRC90_20005	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_20015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_20020	COG1116	anion transmembrane transporter activity
FRC90_20035	COG3046	protein related to deoxyribodipyrimidine photolyase
FRC90_20045	COG3550	peptidyl-serine autophosphorylation
FRC90_20065	COG2032	superoxide dismutase activity
FRC90_20080	COG2204	response regulator
FRC90_20085	COG5000	phosphorelay sensor kinase activity
FRC90_20095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC90_20095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FRC90_20105	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FRC90_20110	COG0085	RNA polymerase activity
FRC90_20115	COG0222	ribosome binding
FRC90_20120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FRC90_20125	COG0081	regulation of translation
FRC90_20130	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FRC90_20140	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FRC90_20150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FRC90_20195	COG0189	ligase activity
FRC90_20200	COG3135	benzoate transporter
FRC90_20205	COG3158	transport of potassium into the cell
FRC90_20215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FRC90_20220	COG0569	domain protein
FRC90_20225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FRC90_20245	COG0495	leucyl-tRNA aminoacylation
FRC90_20255	COG3300	MHYT domain
FRC90_20255	COG5001	Diguanylate cyclase
FRC90_20270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FRC90_20275	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FRC90_20280	COG0735	belongs to the Fur family
FRC90_20285	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FRC90_20295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FRC90_20300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FRC90_20310	COG3118	belongs to the thioredoxin family
FRC90_20315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FRC90_20320	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FRC90_20325	COG0009	L-threonylcarbamoyladenylate synthase
FRC90_20350	COG1214	PFAM Peptidase M22, glycoprotease
FRC90_20365	COG0598	Magnesium transport protein CorA
FRC90_20375	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_20410	COG0469	pyruvate kinase activity
FRC90_20415	COG0006	proline dipeptidase activity
FRC90_20420	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FRC90_20430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FRC90_20450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FRC90_20460	COG0583	DNA-binding transcription factor activity
FRC90_20495	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FRC90_20550	COG0668	transmembrane transport
FRC90_20560	COG2194	sulfuric ester hydrolase activity
FRC90_20565	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_20580	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FRC90_20635	COG1714	RDD family
FRC90_20680	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FRC90_20680	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FRC90_20710	COG0583	DNA-binding transcription factor activity
FRC90_20720	COG0642	Histidine kinase
FRC90_20735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FRC90_20740	COG2137	regulation of response to DNA damage stimulus
FRC90_20750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FRC90_20755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FRC90_20760	COG1862	Preprotein translocase
FRC90_20770	COG1522	sequence-specific DNA binding
FRC90_20780	COG2814	Major facilitator Superfamily
FRC90_20800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FRC90_20830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FRC90_20835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FRC90_20850	COG1309	transcriptional regulator
FRC90_20860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC90_20885	COG0625	glutathione transferase activity
FRC90_20910	COG0861	Integral membrane protein TerC family
FRC90_20920	COG1950	PFAM Membrane protein of
FRC90_20925	COG4783	chaperone-mediated protein folding
FRC90_20930	COG0315	cyclic pyranopterin monophosphate synthase activity
FRC90_20940	COG3307	-O-antigen
FRC90_20950	COG1716	ATPase activity
FRC90_20955	COG0631	protein serine/threonine phosphatase activity
FRC90_20960	COG0861	Integral membrane protein TerC family
FRC90_20965	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FRC90_20970	COG0045	succinate-CoA ligase (ADP-forming) activity
FRC90_20975	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FRC90_20980	COG0758	DNA mediated transformation
FRC90_20990	COG0242	peptide deformylase activity
FRC90_21000	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FRC90_21015	COG0126	phosphoglycerate kinase activity
FRC90_21025	COG0697	spore germination
FRC90_21030	COG0284	orotidine-5'-phosphate decarboxylase activity
FRC90_21035	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FRC90_21065	COG0840	transmembrane signaling receptor activity
FRC90_21105	COG2814	Major facilitator Superfamily
FRC90_21115	COG0629	single-stranded DNA binding
FRC90_21140	COG0640	Transcriptional regulator
FRC90_21170	COG1620	l-lactate permease
FRC90_21175	COG0482	sulfurtransferase activity
FRC90_21180	COG0494	nUDIX hydrolase
FRC90_21210	COG0307	riboflavin synthase, alpha
FRC90_21235	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FRC90_21240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FRC90_21305	COG1802	Transcriptional regulator
FRC90_21360	COG0280	phosphate acetyltransferase
FRC90_21360	COG0281	malic enzyme
FRC90_21375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FRC90_21380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC90_21385	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FRC90_21395	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FRC90_21410	COG1196	nuclear chromosome segregation
FRC90_21415	COG2814	Major facilitator Superfamily
FRC90_21425	COG2207	Transcriptional regulator
FRC90_21430	COG1113	amino acid transport
FRC90_21435	COG4303	Ethanolamine ammonia lyase large subunit
FRC90_21440	COG4302	ethanolamine ammonia-lyase activity
FRC90_21450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC90_21455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC90_21460	COG2119	membrane
FRC90_21465	COG0724	RNA recognition motif
FRC90_21470	COG0724	RNA recognition motif
FRC90_21475	COG0300	oxidoreductase activity
FRC90_21485	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FRC90_21500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FRC90_21520	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FRC90_21530	COG0706	membrane insertase activity
FRC90_21535	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FRC90_21540	COG0594	ribonuclease P activity
FRC90_21545	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FRC90_21550	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FRC90_21590	COG1764	response to oxidative stress
FRC90_21610	COG1199	ATP-dependent helicase activity
FRC90_21625	COG2176	DNA-directed DNA polymerase activity
FRC90_21640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC90_21645	COG0791	NLP P60 protein
FRC90_21650	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FRC90_21670	COG2974	May be involved in recombination
FRC90_21675	COG2715	membrane protein required for spore maturation
FRC90_21700	COG0183	Belongs to the thiolase family
FRC90_21705	COG0789	Transcriptional regulator
FRC90_21715	COG2217	Heavy metal translocating P-type atpase
FRC90_21750	COG0745	RESPONSE REGULATOR receiver
FRC90_21755	COG0642	Histidine kinase
FRC90_21775	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FRC90_21780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_21800	COG0445	tRNA wobble uridine modification
FRC90_21805	COG0357	Ribosomal RNA small subunit methyltransferase G
FRC90_21810	COG1280	lysine exporter protein (LysE YggA)
FRC90_21815	COG1192	Involved in chromosome partitioning
FRC90_21840	COG0493	'glutamate synthase
FRC90_21860	COG0277	FAD linked oxidase domain protein
FRC90_21865	COG0546	phosphoglycolate phosphatase activity
FRC90_21865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FRC90_21880	COG2272	Belongs to the type-B carboxylesterase lipase family
FRC90_21900	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FRC90_21935	COG3411	Ferredoxin
FRC90_21950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC90_22040	COG0277	FAD linked oxidase domain protein
FRC90_22055	COG2096	Adenosyltransferase
FRC90_22060	COG2050	protein possibly involved in aromatic compounds catabolism
FRC90_22075	COG2233	PERMEase
FRC90_22095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FRC90_22125	COG1116	anion transmembrane transporter activity
FRC90_22130	COG0395	ABC-type sugar transport system, permease component
FRC90_22150	COG1414	Transcriptional regulator
FRC90_22155	COG0501	Belongs to the peptidase M48B family
FRC90_22165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FRC90_22180	COG2423	ornithine cyclodeaminase activity
FRC90_22190	COG1183	phosphatidylcholine synthase activity
FRC90_22200	COG0850	regulation of cytokinetic process
FRC90_22205	COG2894	cell division
FRC90_22210	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FRC90_22215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC90_22230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FRC90_22235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_22270	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FRC90_22275	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FRC90_22280	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FRC90_22285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC90_22295	COG1960	acyl-CoA dehydrogenase activity
FRC90_22315	COG0625	glutathione transferase activity
FRC90_22320	COG2271	Major facilitator Superfamily
FRC90_22330	COG2423	ornithine cyclodeaminase activity
FRC90_22360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FRC90_22415	COG0840	transmembrane signaling receptor activity
FRC90_22450	COG0583	DNA-binding transcription factor activity
FRC90_22465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_22470	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_22510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FRC90_22520	COG2326	polyphosphate kinase activity
FRC90_22560	COG0583	DNA-binding transcription factor activity