locus-tag	class	description
FRC97_00005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FRC97_00060	COG3736	Type IV secretory pathway, component VirB8
FRC97_00065	COG3504	Conjugal transfer protein
FRC97_00080	COG3505	Type IV secretory pathway VirD4
FRC97_00085	COG2885	chlorophyll binding
FRC97_00250	COG1475	DNA binding
FRC97_00305	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FRC97_00315	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FRC97_00320	COG0243	molybdopterin cofactor binding
FRC97_00325	COG0840	transmembrane signaling receptor activity
FRC97_00330	COG2223	nitrite transmembrane transporter activity
FRC97_00335	COG0489	protein tyrosine kinase activity
FRC97_00350	COG0028	Belongs to the TPP enzyme family
FRC97_00355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC97_00355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC97_00385	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FRC97_00395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FRC97_00400	COG0156	8-amino-7-oxononanoate synthase activity
FRC97_00405	COG0602	queuosine metabolic process
FRC97_00410	COG0720	synthase
FRC97_00435	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FRC97_00445	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FRC97_00450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FRC97_00455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FRC97_00460	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FRC97_00470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FRC97_00475	COG0588	phosphoglycerate mutase activity
FRC97_00480	COG0793	Belongs to the peptidase S41A family
FRC97_00485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FRC97_00495	COG2197	response regulator
FRC97_00505	COG5487	UPF0391 membrane protein
FRC97_00530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FRC97_00535	COG0742	ribosomal rna small subunit methyltransferase
FRC97_00540	COG0612	Peptidase, M16
FRC97_00545	COG0612	Peptidase, M16
FRC97_00555	COG0179	Fumarylacetoacetate (FAA) hydrolase
FRC97_00580	COG0840	transmembrane signaling receptor activity
FRC97_00585	COG4977	sequence-specific DNA binding
FRC97_00600	COG0534	Mate efflux family protein
FRC97_00635	COG3842	ATPase activity
FRC97_00645	COG0583	DNA-binding transcription factor activity
FRC97_00660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FRC97_00680	COG1999	signal sequence binding
FRC97_00685	COG0109	protoheme IX farnesyltransferase activity
FRC97_00690	COG1612	heme a metabolic process
FRC97_00735	COG2226	methyltransferase
FRC97_00740	COG1040	competence protein
FRC97_00745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FRC97_00750	COG0583	DNA-binding transcription factor activity
FRC97_00765	COG1192	Involved in chromosome partitioning
FRC97_00770	COG1280	lysine exporter protein (LysE YggA)
FRC97_00780	COG4774	siderophore transport
FRC97_00800	COG3038	cytochrome b561
FRC97_00805	COG1846	Transcriptional regulator
FRC97_00810	COG0840	transmembrane signaling receptor activity
FRC97_00815	COG0477	Major facilitator Superfamily
FRC97_00825	COG2010	Cytochrome c
FRC97_00825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_00830	COG2080	2 iron, 2 sulfur cluster binding
FRC97_00840	COG3473	Maleate cis-trans isomerase
FRC97_00845	COG0596	Alpha beta hydrolase
FRC97_00850	COG2309	aminopeptidase activity
FRC97_00855	COG1335	isochorismatase
FRC97_00860	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_00860	COG2010	Cytochrome c
FRC97_00880	COG3387	PFAM Glycoside hydrolase 15-related
FRC97_00885	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_00895	COG2031	fatty acid transporter
FRC97_00915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC97_00920	COG0183	Belongs to the thiolase family
FRC97_00925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FRC97_00935	COG1414	Transcriptional regulator
FRC97_00965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FRC97_01035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC97_01050	COG0346	lactoylglutathione lyase activity
FRC97_01080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FRC97_01110	COG1132	(ABC) transporter
FRC97_01115	COG0189	ligase activity
FRC97_01115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC97_01120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC97_01120	COG1181	Belongs to the D-alanine--D-alanine ligase family
FRC97_01125	COG3045	CreA protein
FRC97_01140	COG3145	DNA-N1-methyladenine dioxygenase activity
FRC97_01155	COG0753	catalase activity
FRC97_01160	COG0745	RESPONSE REGULATOR receiver
FRC97_01165	COG0784	Response regulator, receiver
FRC97_01165	COG5002	protein histidine kinase activity
FRC97_01175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FRC97_01210	COG0601	transmembrane transport
FRC97_01215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC97_01225	COG0514	ATP-dependent DNA helicase (RecQ)
FRC97_01245	COG3209	COG3209 Rhs family protein
FRC97_01245	COG3209	COG3209 Rhs family protein
FRC97_01265	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_01270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FRC97_01275	COG2080	2 iron, 2 sulfur cluster binding
FRC97_01315	COG0737	Belongs to the 5'-nucleotidase family
FRC97_01320	COG0583	DNA-binding transcription factor activity
FRC97_01325	COG2855	membrane
FRC97_01335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FRC97_01360	COG2267	carboxylic ester hydrolase activity
FRC97_01370	COG3002	Belongs to the UPF0753 family
FRC97_01375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FRC97_01420	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FRC97_01445	COG0583	DNA-binding transcription factor activity
FRC97_01450	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FRC97_01460	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FRC97_01465	COG2814	Major facilitator Superfamily
FRC97_01470	COG0316	Belongs to the HesB IscA family
FRC97_01485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FRC97_01490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FRC97_01495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FRC97_01495	COG0515	serine threonine protein kinase
FRC97_01500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FRC97_01505	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FRC97_01530	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FRC97_01540	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FRC97_01550	COG2076	Multidrug Resistance protein
FRC97_01580	COG1126	abc transporter atp-binding protein
FRC97_01585	COG0765	amino acid transport
FRC97_01590	COG0765	amino acid transport
FRC97_01595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_01605	COG0583	DNA-binding transcription factor activity
FRC97_01610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC97_01615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC97_01615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC97_01620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_01625	COG5265	(ABC) transporter
FRC97_01640	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_01645	COG1024	Enoyl-CoA hydratase
FRC97_01655	COG0183	Belongs to the thiolase family
FRC97_01675	COG1960	acyl-CoA dehydrogenase activity
FRC97_01685	COG1309	transcriptional regulator
FRC97_01695	COG0745	RESPONSE REGULATOR receiver
FRC97_01700	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FRC97_01740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC97_01755	COG1450	Type ii and iii secretion system protein
FRC97_01785	COG2165	general secretion pathway protein
FRC97_01790	COG4970	Tfp pilus assembly protein FimT
FRC97_01795	COG2165	general secretion pathway protein
FRC97_01800	COG1459	type II secretion system
FRC97_01805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FRC97_01845	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FRC97_01850	COG1652	LysM domain
FRC97_01870	COG0204	Acyl-transferase
FRC97_01875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FRC97_01885	COG0751	glycine-tRNA ligase activity
FRC97_01890	COG0752	glycyl-tRNA synthetase alpha subunit
FRC97_01895	COG3258	Cytochrome c
FRC97_01905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FRC97_01920	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FRC97_01925	COG4535	Mg2 and Co2 transporter CorC
FRC97_01940	COG1522	sequence-specific DNA binding
FRC97_01945	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FRC97_01965	COG3186	Phenylalanine-4-hydroxylase
FRC97_01980	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_01990	COG1129	ABC transporter
FRC97_01995	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC97_02005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FRC97_02010	COG1869	D-ribose catabolic process
FRC97_02025	COG1196	nuclear chromosome segregation
FRC97_02025	COG0741	lytic transglycosylase activity
FRC97_02025	COG0739	heme binding
FRC97_02030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FRC97_02055	COG0617	tRNA 3'-terminal CCA addition
FRC97_02070	COG3387	PFAM Glycoside hydrolase 15-related
FRC97_02075	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FRC97_02095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_02110	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_02120	COG2879	small protein
FRC97_02125	COG1966	Carbon starvation protein
FRC97_02130	COG2197	response regulator
FRC97_02140	COG0037	tRNA processing
FRC97_02175	COG2255	four-way junction helicase activity
FRC97_02190	COG0632	four-way junction helicase activity
FRC97_02195	COG1702	phosphate starvation-inducible protein PhoH
FRC97_02215	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FRC97_02220	COG1490	D-aminoacyl-tRNA deacylase activity
FRC97_02225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FRC97_02230	COG0513	Belongs to the DEAD box helicase family
FRC97_02235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FRC97_02240	COG3706	GGDEF domain
FRC97_02255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FRC97_02255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FRC97_02265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FRC97_02265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FRC97_02285	COG0443	Heat shock 70 kDa protein
FRC97_02295	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FRC97_02300	COG1131	(ABC) transporter
FRC97_02305	COG0842	Transport permease protein
FRC97_02310	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC97_02320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC97_02340	COG0179	Fumarylacetoacetate (FAA) hydrolase
FRC97_02345	COG3971	2-oxopent-4-enoate hydratase activity
FRC97_02355	COG1846	Transcriptional regulator
FRC97_02360	COG1764	response to oxidative stress
FRC97_02370	COG2815	serine threonine protein kinase
FRC97_02370	COG0515	serine threonine protein kinase
FRC97_02415	COG3209	COG3209 Rhs family protein
FRC97_02460	COG0326	Molecular chaperone. Has ATPase activity
FRC97_02490	COG0840	transmembrane signaling receptor activity
FRC97_02510	COG3568	Endonuclease Exonuclease Phosphatase
FRC97_02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC97_02520	COG0392	lysyltransferase activity
FRC97_02525	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FRC97_02535	COG0840	transmembrane signaling receptor activity
FRC97_02570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_02575	COG1024	Enoyl-CoA hydratase
FRC97_02580	COG1960	acyl-CoA dehydrogenase activity
FRC97_02585	COG1960	acyl-CoA dehydrogenase activity
FRC97_02590	COG1024	Enoyl-CoA hydratase
FRC97_02590	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC97_02595	COG0583	DNA-binding transcription factor activity
FRC97_02600	COG0501	Belongs to the peptidase M48B family
FRC97_02615	COG0418	dihydroorotase activity
FRC97_02620	COG2205	protein histidine kinase activity
FRC97_02625	COG0745	RESPONSE REGULATOR receiver
FRC97_02640	COG0577	efflux transmembrane transporter activity
FRC97_02640	COG1136	(ABC) transporter
FRC97_02670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FRC97_02720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FRC97_02735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FRC97_02770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC97_02785	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FRC97_02790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FRC97_02795	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_02815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FRC97_02820	COG2198	Histidine kinase
FRC97_02820	COG2205	protein histidine kinase activity
FRC97_02820	COG0784	Response regulator, receiver
FRC97_02825	COG3012	SEC-C Motif Domain Protein
FRC97_02840	COG1960	acyl-CoA dehydrogenase activity
FRC97_02855	COG0183	Belongs to the thiolase family
FRC97_02860	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FRC97_02865	COG0288	reversible hydration of carbon dioxide
FRC97_02870	COG1960	acyl-CoA dehydrogenase activity
FRC97_02880	COG0789	Transcriptional regulator
FRC97_02910	COG0488	(ABC) transporter
FRC97_02915	COG2201	protein-glutamate methylesterase activity
FRC97_02920	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FRC97_02925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FRC97_02930	COG0835	chemotaxis
FRC97_02935	COG0643	Histidine kinase
FRC97_02935	COG2198	Histidine kinase
FRC97_02940	COG0745	RESPONSE REGULATOR receiver
FRC97_02950	COG3851	Histidine kinase
FRC97_02955	COG2197	response regulator
FRC97_02965	COG1987	bacterial-type flagellum assembly
FRC97_02980	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FRC97_02990	COG1580	Controls the rotational direction of flagella during chemotaxis
FRC97_03020	COG1766	The M ring may be actively involved in energy transduction
FRC97_03025	COG1677	Flagellar hook-basal body complex protein FliE
FRC97_03060	COG4106	trans-aconitate 2-methyltransferase activity
FRC97_03070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_03075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FRC97_03080	COG1216	Glycosyl transferase, family 2
FRC97_03080	COG0438	transferase activity, transferring glycosyl groups
FRC97_03085	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FRC97_03090	COG1360	Flagellar Motor Protein
FRC97_03095	COG0745	RESPONSE REGULATOR receiver
FRC97_03100	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FRC97_03105	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FRC97_03145	COG1815	bacterial-type flagellum-dependent cell motility
FRC97_03150	COG1558	bacterial-type flagellum-dependent cell motility
FRC97_03155	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FRC97_03165	COG4787	bacterial-type flagellum-dependent cell motility
FRC97_03175	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FRC97_03185	COG1706	bacterial-type flagellum-dependent cell motility
FRC97_03190	COG3951	Flagellar rod assembly protein muramidase FlgJ
FRC97_03190	COG1705	Flagellar rod assembly protein muramidase FlgJ
FRC97_03200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FRC97_03220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC97_03230	COG0697	spore germination
FRC97_03235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC97_03240	COG0625	glutathione transferase activity
FRC97_03245	COG0384	phenazine biosynthesis protein PhzF
FRC97_03275	COG0840	transmembrane signaling receptor activity
FRC97_03320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FRC97_03350	COG0861	Integral membrane protein TerC family
FRC97_03355	COG0583	DNA-binding transcription factor activity
FRC97_03375	COG3119	arylsulfatase activity
FRC97_03390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FRC97_03400	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FRC97_03420	COG0210	DNA helicase
FRC97_03445	COG0343	queuine tRNA-ribosyltransferase activity
FRC97_03485	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_03515	COG1522	sequence-specific DNA binding
FRC97_03520	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FRC97_03530	COG0840	transmembrane signaling receptor activity
FRC97_03570	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_03575	COG2072	flavoprotein involved in K transport
FRC97_03585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_03605	COG2365	Tyrosine phosphatase family
FRC97_03610	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_03620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_03625	COG1116	anion transmembrane transporter activity
FRC97_03640	COG3046	protein related to deoxyribodipyrimidine photolyase
FRC97_03665	COG2032	superoxide dismutase activity
FRC97_03680	COG2204	response regulator
FRC97_03685	COG5000	phosphorelay sensor kinase activity
FRC97_03695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC97_03695	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FRC97_03705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FRC97_03710	COG0085	RNA polymerase activity
FRC97_03715	COG0222	ribosome binding
FRC97_03720	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FRC97_03725	COG0081	regulation of translation
FRC97_03730	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FRC97_03740	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FRC97_03750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FRC97_03795	COG0189	ligase activity
FRC97_03800	COG3135	benzoate transporter
FRC97_03805	COG3158	transport of potassium into the cell
FRC97_03820	COG0569	domain protein
FRC97_03825	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FRC97_03845	COG0495	leucyl-tRNA aminoacylation
FRC97_03855	COG5001	Diguanylate cyclase
FRC97_03855	COG3300	MHYT domain
FRC97_03870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FRC97_03875	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FRC97_03880	COG0735	belongs to the Fur family
FRC97_03885	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FRC97_03895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FRC97_03905	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FRC97_03915	COG3118	belongs to the thioredoxin family
FRC97_03920	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FRC97_03925	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FRC97_03930	COG0009	L-threonylcarbamoyladenylate synthase
FRC97_03955	COG1214	PFAM Peptidase M22, glycoprotease
FRC97_03970	COG0598	Magnesium transport protein CorA
FRC97_03980	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_04015	COG0469	pyruvate kinase activity
FRC97_04020	COG0006	proline dipeptidase activity
FRC97_04025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FRC97_04035	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FRC97_04055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FRC97_04065	COG0583	DNA-binding transcription factor activity
FRC97_04100	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FRC97_04155	COG0668	transmembrane transport
FRC97_04165	COG2194	sulfuric ester hydrolase activity
FRC97_04170	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_04185	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FRC97_04240	COG1714	RDD family
FRC97_04285	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FRC97_04285	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FRC97_04315	COG0583	DNA-binding transcription factor activity
FRC97_04325	COG0642	Histidine kinase
FRC97_04340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FRC97_04345	COG2137	regulation of response to DNA damage stimulus
FRC97_04355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FRC97_04360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FRC97_04365	COG1862	Preprotein translocase
FRC97_04375	COG1522	sequence-specific DNA binding
FRC97_04385	COG2814	Major facilitator Superfamily
FRC97_04405	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FRC97_04435	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FRC97_04440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FRC97_04455	COG1309	transcriptional regulator
FRC97_04465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC97_04490	COG0625	glutathione transferase activity
FRC97_04515	COG0861	Integral membrane protein TerC family
FRC97_04525	COG1950	PFAM Membrane protein of
FRC97_04530	COG4783	chaperone-mediated protein folding
FRC97_04535	COG0315	cyclic pyranopterin monophosphate synthase activity
FRC97_04545	COG3307	-O-antigen
FRC97_04555	COG1716	ATPase activity
FRC97_04560	COG0631	protein serine/threonine phosphatase activity
FRC97_04565	COG0861	Integral membrane protein TerC family
FRC97_04570	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FRC97_04575	COG0045	succinate-CoA ligase (ADP-forming) activity
FRC97_04580	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FRC97_04585	COG0758	DNA mediated transformation
FRC97_04595	COG0242	peptide deformylase activity
FRC97_04605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FRC97_04620	COG0126	phosphoglycerate kinase activity
FRC97_04630	COG0697	spore germination
FRC97_04635	COG0284	orotidine-5'-phosphate decarboxylase activity
FRC97_04640	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FRC97_04670	COG0840	transmembrane signaling receptor activity
FRC97_04710	COG2814	Major facilitator Superfamily
FRC97_04720	COG0629	single-stranded DNA binding
FRC97_04745	COG0640	Transcriptional regulator
FRC97_04775	COG1620	l-lactate permease
FRC97_04780	COG0482	sulfurtransferase activity
FRC97_04785	COG0494	nUDIX hydrolase
FRC97_04815	COG0307	riboflavin synthase, alpha
FRC97_04840	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FRC97_04845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FRC97_04905	COG1802	Transcriptional regulator
FRC97_04955	COG0280	phosphate acetyltransferase
FRC97_04955	COG0281	malic enzyme
FRC97_04970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FRC97_04975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC97_04980	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FRC97_04990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FRC97_05005	COG1196	nuclear chromosome segregation
FRC97_05010	COG2814	Major facilitator Superfamily
FRC97_05020	COG2207	Transcriptional regulator
FRC97_05025	COG1113	amino acid transport
FRC97_05030	COG4303	Ethanolamine ammonia lyase large subunit
FRC97_05035	COG4302	ethanolamine ammonia-lyase activity
FRC97_05045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC97_05050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC97_05055	COG2119	membrane
FRC97_05060	COG0724	RNA recognition motif
FRC97_05065	COG0724	RNA recognition motif
FRC97_05070	COG0300	oxidoreductase activity
FRC97_05080	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FRC97_05095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FRC97_05115	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FRC97_05125	COG0706	membrane insertase activity
FRC97_05130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FRC97_05135	COG0594	ribonuclease P activity
FRC97_05140	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FRC97_05145	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FRC97_05195	COG1764	response to oxidative stress
FRC97_05215	COG1199	ATP-dependent helicase activity
FRC97_05230	COG2176	DNA-directed DNA polymerase activity
FRC97_05245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC97_05250	COG0791	NLP P60 protein
FRC97_05255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FRC97_05275	COG2974	May be involved in recombination
FRC97_05280	COG2715	membrane protein required for spore maturation
FRC97_05305	COG0183	Belongs to the thiolase family
FRC97_05310	COG0789	Transcriptional regulator
FRC97_05320	COG2217	Heavy metal translocating P-type atpase
FRC97_05355	COG0745	RESPONSE REGULATOR receiver
FRC97_05360	COG0642	Histidine kinase
FRC97_05380	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FRC97_05385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_05405	COG0445	tRNA wobble uridine modification
FRC97_05410	COG0357	Ribosomal RNA small subunit methyltransferase G
FRC97_05415	COG1280	lysine exporter protein (LysE YggA)
FRC97_05420	COG1192	Involved in chromosome partitioning
FRC97_05445	COG0493	'glutamate synthase
FRC97_05465	COG0277	FAD linked oxidase domain protein
FRC97_05470	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FRC97_05470	COG0546	phosphoglycolate phosphatase activity
FRC97_05485	COG2272	Belongs to the type-B carboxylesterase lipase family
FRC97_05505	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FRC97_05540	COG3411	Ferredoxin
FRC97_05555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC97_05645	COG0277	FAD linked oxidase domain protein
FRC97_05660	COG2096	Adenosyltransferase
FRC97_05665	COG2050	protein possibly involved in aromatic compounds catabolism
FRC97_05680	COG2233	PERMEase
FRC97_05700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FRC97_05730	COG1116	anion transmembrane transporter activity
FRC97_05735	COG0395	ABC-type sugar transport system, permease component
FRC97_05755	COG1414	Transcriptional regulator
FRC97_05760	COG0501	Belongs to the peptidase M48B family
FRC97_05770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FRC97_05785	COG2423	ornithine cyclodeaminase activity
FRC97_05795	COG1183	phosphatidylcholine synthase activity
FRC97_05805	COG0850	regulation of cytokinetic process
FRC97_05810	COG2894	cell division
FRC97_05815	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FRC97_05820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC97_05835	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FRC97_05840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_05875	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FRC97_05880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FRC97_05885	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FRC97_05890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC97_05900	COG1960	acyl-CoA dehydrogenase activity
FRC97_05920	COG0625	glutathione transferase activity
FRC97_05925	COG2271	Major facilitator Superfamily
FRC97_05935	COG2423	ornithine cyclodeaminase activity
FRC97_05965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FRC97_06020	COG0840	transmembrane signaling receptor activity
FRC97_06055	COG0583	DNA-binding transcription factor activity
FRC97_06070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_06075	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_06115	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FRC97_06125	COG2326	polyphosphate kinase activity
FRC97_06165	COG0583	DNA-binding transcription factor activity
FRC97_06210	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FRC97_06215	COG1126	abc transporter atp-binding protein
FRC97_06220	COG0765	amino acid transport
FRC97_06225	COG0765	amino acid transport
FRC97_06250	COG0646	methionine synthase
FRC97_06250	COG1410	methionine synthase
FRC97_06310	COG0583	DNA-binding transcription factor activity
FRC97_06320	COG0840	transmembrane signaling receptor activity
FRC97_06325	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_06330	COG4191	Histidine kinase
FRC97_06340	COG0606	chelatase, subunit chli
FRC97_06350	COG0347	Belongs to the P(II) protein family
FRC97_06355	COG0004	ammonium transporteR
FRC97_06400	COG0277	FAD linked oxidase domain protein
FRC97_06410	COG0247	lactate metabolic process
FRC97_06440	COG0386	Belongs to the glutathione peroxidase family
FRC97_06450	COG0477	Major facilitator Superfamily
FRC97_06455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FRC97_06465	COG0747	negative chemotaxis
FRC97_06485	COG0625	glutathione transferase activity
FRC97_06490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FRC97_06535	COG1215	transferase activity, transferring glycosyl groups
FRC97_06555	COG0477	Major facilitator Superfamily
FRC97_06570	COG0745	RESPONSE REGULATOR receiver
FRC97_06575	COG2211	Major facilitator Superfamily
FRC97_06595	COG0501	Belongs to the peptidase M48B family
FRC97_06600	COG0471	metal ion transport
FRC97_06605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FRC97_06625	COG0583	DNA-binding transcription factor activity
FRC97_06630	COG2814	Major facilitator Superfamily
FRC97_06640	COG0708	Exodeoxyribonuclease III
FRC97_06645	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FRC97_06655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FRC97_06660	COG0154	amidase activity
FRC97_06665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FRC97_06670	COG1077	Cell shape determining protein MreB Mrl
FRC97_06680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FRC97_06685	COG0768	penicillin binding
FRC97_06700	COG0765	amino acid transport
FRC97_06705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_06710	COG1760	l-serine dehydratase
FRC97_06730	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FRC97_06735	COG1127	ABC transporter
FRC97_06760	COG3237	CsbD-like
FRC97_06780	COG4452	Inner membrane protein CreD
FRC97_06785	COG2205	protein histidine kinase activity
FRC97_06790	COG0745	RESPONSE REGULATOR receiver
FRC97_06795	COG2095	MarC family integral membrane protein
FRC97_06800	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_06805	COG0412	Dienelactone hydrolase
FRC97_06815	COG1566	PFAM secretion protein HlyD family protein
FRC97_06825	COG1846	Transcriptional regulator
FRC97_06830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FRC97_06830	COG0519	Catalyzes the synthesis of GMP from XMP
FRC97_06835	COG0598	Magnesium transport protein CorA
FRC97_06845	COG1981	membrane
FRC97_06860	COG2945	thiolester hydrolase activity
FRC97_06865	COG1686	Belongs to the peptidase S11 family
FRC97_06870	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FRC97_06875	COG0049	tRNA binding
FRC97_06880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FRC97_06885	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FRC97_06890	COG0051	transcription antitermination factor activity, RNA binding
FRC97_06895	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FRC97_06900	COG0088	Forms part of the polypeptide exit tunnel
FRC97_06905	COG0089	rRNA binding
FRC97_06910	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FRC97_06915	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FRC97_06920	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FRC97_06925	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FRC97_06930	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FRC97_06935	COG0255	Belongs to the universal ribosomal protein uL29 family
FRC97_06940	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FRC97_06945	COG0678	peroxiredoxin activity
FRC97_06955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FRC97_06970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FRC97_06975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FRC97_06990	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FRC97_06995	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FRC97_07000	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FRC97_07005	COG2205	protein histidine kinase activity
FRC97_07010	COG0745	RESPONSE REGULATOR receiver
FRC97_07025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FRC97_07030	COG0321	lipoyl(octanoyl) transferase activity
FRC97_07035	COG2921	Belongs to the UPF0250 family
FRC97_07045	COG0356	it plays a direct role in the translocation of protons across the membrane
FRC97_07055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FRC97_07060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FRC97_07065	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FRC97_07070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FRC97_07075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FRC97_07080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FRC97_07085	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FRC97_07085	COG1793	dna ligase
FRC97_07090	COG1793	dna ligase
FRC97_07095	COG1201	RNA secondary structure unwinding
FRC97_07145	COG3245	cytochrome
FRC97_07160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC97_07165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC97_07245	COG0121	glutamine amidotransferase
FRC97_07250	COG2814	Major facilitator Superfamily
FRC97_07255	COG1942	4-Oxalocrotonate Tautomerase
FRC97_07265	COG0840	transmembrane signaling receptor activity
FRC97_07270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FRC97_07300	COG0018	arginyl-trna synthetase
FRC97_07310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FRC97_07320	COG1137	ATPase activity
FRC97_07325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FRC97_07330	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FRC97_07350	COG4178	(ABC) transporter
FRC97_07360	COG0653	protein targeting
FRC97_07365	COG0659	secondary active sulfate transmembrane transporter activity
FRC97_07380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FRC97_07400	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FRC97_07415	COG2967	ApaG domain
FRC97_07420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FRC97_07430	COG0546	phosphoglycolate phosphatase activity
FRC97_07450	COG2207	Transcriptional regulator
FRC97_07470	COG4794	Type iii secretion
FRC97_07475	COG4790	Type iii secretion
FRC97_07490	COG4789	Type iii secretion
FRC97_07495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FRC97_07615	COG0500	methyltransferase
FRC97_07620	COG0739	heme binding
FRC97_07620	COG0741	lytic transglycosylase activity
FRC97_07620	COG1196	nuclear chromosome segregation
FRC97_07645	COG0512	Glutamine amidotransferase of anthranilate synthase
FRC97_07650	COG1280	lysine exporter protein (LysE YggA)
FRC97_07655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FRC97_07660	COG0134	indole-3-glycerol-phosphate synthase activity
FRC97_07665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FRC97_07700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FRC97_07710	COG0783	Belongs to the Dps family
FRC97_07715	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FRC97_07730	COG0463	Glycosyl transferase, family 2
FRC97_07745	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FRC97_07755	COG3842	ATPase activity
FRC97_07760	COG3842	ATPase activity
FRC97_07770	COG0395	ABC-type sugar transport system, permease component
FRC97_07790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FRC97_07795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FRC97_07800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FRC97_07805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FRC97_07810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FRC97_07815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FRC97_07820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FRC97_07825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FRC97_07830	COG1841	ribosomal large subunit assembly
FRC97_07835	COG0200	Binds to the 23S rRNA
FRC97_07840	COG0201	protein transport
FRC97_07845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FRC97_07850	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FRC97_07855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FRC97_07860	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FRC97_07865	COG0202	RNA polymerase activity
FRC97_07870	COG0203	ribosomal protein L17
FRC97_07880	COG0443	Heat shock 70 kDa protein
FRC97_07885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FRC97_07890	COG0792	nuclease activity
FRC97_07895	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FRC97_07900	COG2823	Periplasmic or secreted lipoprotein
FRC97_07905	COG2084	Dehydrogenase
FRC97_07915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FRC97_07940	COG2733	membrane
FRC97_07960	COG0277	FAD linked oxidase domain protein
FRC97_07970	COG0583	DNA-binding transcription factor activity
FRC97_07990	COG1285	pathogenesis
FRC97_08000	COG3850	Histidine kinase
FRC97_08005	COG2197	response regulator
FRC97_08020	COG4771	TonB-dependent receptor
FRC97_08035	COG2223	nitrite transmembrane transporter activity
FRC97_08040	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FRC97_08045	COG1140	nitrate reductase beta subunit
FRC97_08050	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FRC97_08055	COG2181	nitrate reductase activity
FRC97_08060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC97_08065	COG0288	reversible hydration of carbon dioxide
FRC97_08080	COG3945	hemerythrin HHE cation binding domain
FRC97_08095	COG0477	Major facilitator Superfamily
FRC97_08140	COG1272	protein, Hemolysin III
FRC97_08200	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC97_08205	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC97_08215	COG0129	dihydroxy-acid dehydratase activity
FRC97_08220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_08230	COG0583	DNA-binding transcription factor activity
FRC97_08235	COG1741	Belongs to the pirin family
FRC97_08240	COG1335	isochorismatase
FRC97_08280	COG0243	molybdopterin cofactor binding
FRC97_08295	COG1473	amidohydrolase
FRC97_08320	COG0519	Catalyzes the synthesis of GMP from XMP
FRC97_08325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC97_08380	COG3267	Type II secretory pathway component ExeA
FRC97_08380	COG3409	Peptidoglycan-binding domain 1 protein
FRC97_08385	COG3266	domain, Protein
FRC97_08400	COG4269	membrane
FRC97_08435	COG0625	glutathione transferase activity
FRC97_08440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FRC97_08450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FRC97_08455	COG1649	PFAM Uncharacterised BCR, COG1649
FRC97_08475	COG3447	MASE1 domain protein
FRC97_08475	COG5001	Diguanylate cyclase
FRC97_08475	COG5002	protein histidine kinase activity
FRC97_08480	COG0523	cobalamin synthesis protein
FRC97_08495	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FRC97_08500	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FRC97_08505	COG2001	Belongs to the MraZ family
FRC97_08510	COG0275	rRNA processing
FRC97_08515	COG3116	cell division
FRC97_08525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC97_08530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FRC97_08535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FRC97_08540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FRC97_08545	COG0772	Belongs to the SEDS family
FRC97_08550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FRC97_08555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FRC97_08560	COG1181	Belongs to the D-alanine--D-alanine ligase family
FRC97_08565	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FRC97_08575	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FRC97_08580	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FRC97_08585	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FRC97_08590	COG0840	transmembrane signaling receptor activity
FRC97_08605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FRC97_08610	COG0575	Belongs to the CDS family
FRC97_08635	COG1414	Transcriptional regulator
FRC97_08640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC97_08645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FRC97_08655	COG0557	exoribonuclease II activity
FRC97_08665	COG3150	esterase
FRC97_08670	COG0772	Belongs to the SEDS family
FRC97_08675	COG0154	amidase activity
FRC97_08680	COG0312	modulator of DNA gyrase
FRC97_08690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FRC97_08700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FRC97_08710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FRC97_08715	COG0511	ligase activity, forming carbon-carbon bonds
FRC97_08720	COG0439	Biotin carboxylase
FRC97_08725	COG2264	protein methyltransferase activity
FRC97_08735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FRC97_08745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FRC97_08780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FRC97_08790	COG2204	response regulator
FRC97_08800	COG2205	protein histidine kinase activity
FRC97_08805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FRC97_08830	COG0431	NADPH-dependent FMN reductase
FRC97_08835	COG3829	transcription factor binding
FRC97_08840	COG1024	Enoyl-CoA hydratase
FRC97_08855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FRC97_08860	COG3217	Mosc domain protein beta barrel domain protein
FRC97_08860	COG0633	Ferredoxin
FRC97_08865	COG0012	GTP binding
FRC97_08880	COG0517	IMP dehydrogenase activity
FRC97_08880	COG1125	glycine betaine transport
FRC97_08890	COG1238	metal cluster binding
FRC97_08900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC97_08905	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FRC97_08910	COG0138	bifunctional purine biosynthesis protein purh
FRC97_08920	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FRC97_08925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FRC97_08925	COG0352	thiamine-phosphate diphosphorylase activity
FRC97_08925	COG0351	phosphomethylpyrimidine kinase
FRC97_08930	COG1773	rubredoxin
FRC97_08945	COG0835	chemotaxis
FRC97_08950	COG0840	transmembrane signaling receptor activity
FRC97_08955	COG2198	Histidine kinase
FRC97_08955	COG0643	Histidine kinase
FRC97_08960	COG0415	Belongs to the DNA photolyase family
FRC97_08965	COG1678	Uncharacterized ACR, COG1678
FRC97_08970	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FRC97_08975	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FRC97_08980	COG0540	Belongs to the ATCase OTCase family
FRC97_09000	COG3842	ATPase activity
FRC97_09005	COG1178	ABC-type Fe3 transport system permease component
FRC97_09055	COG4970	Tfp pilus assembly protein FimT
FRC97_09075	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FRC97_09080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC97_09085	COG1765	OsmC-like protein
FRC97_09090	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FRC97_09110	COG1473	amidohydrolase
FRC97_09115	COG0747	negative chemotaxis
FRC97_09120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC97_09125	COG0444	Belongs to the ABC transporter superfamily
FRC97_09130	COG4608	Belongs to the ABC transporter superfamily
FRC97_09135	COG0840	transmembrane signaling receptor activity
FRC97_09150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FRC97_09155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FRC97_09160	COG0166	Belongs to the GPI family
FRC97_09165	COG0459	protein refolding
FRC97_09170	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FRC97_09185	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FRC97_09220	COG2226	methyltransferase
FRC97_09225	COG0438	transferase activity, transferring glycosyl groups
FRC97_09235	COG0367	asparagine synthase
FRC97_09240	COG0438	transferase activity, transferring glycosyl groups
FRC97_09245	COG0367	asparagine synthase
FRC97_09265	COG1216	Glycosyl transferase, family 2
FRC97_09275	COG1309	transcriptional regulator
FRC97_09280	COG0493	'glutamate synthase
FRC97_09290	COG1953	Uracil, thiamine, allantoin
FRC97_09325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FRC97_09325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FRC97_09330	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FRC97_09345	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FRC97_09355	COG1560	Kdo2-lipid A biosynthetic process
FRC97_09365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FRC97_09375	COG1333	cytochrome c biogenesis protein
FRC97_09380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FRC97_09385	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FRC97_09390	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FRC97_09420	COG1965	Belongs to the frataxin family
FRC97_09460	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FRC97_09465	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FRC97_09470	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FRC97_09490	COG0070	glutamate synthase
FRC97_09490	COG0067	glutamate synthase
FRC97_09490	COG0069	glutamate synthase activity
FRC97_09500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_09505	COG0765	amino acid transport
FRC97_09510	COG1126	abc transporter atp-binding protein
FRC97_09515	COG1127	ABC transporter
FRC97_09520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FRC97_09525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FRC97_09530	COG2853	Lipoprotein
FRC97_09550	COG1131	(ABC) transporter
FRC97_09555	COG0842	Transport permease protein
FRC97_09560	COG5007	Belongs to the BolA IbaG family
FRC97_09565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FRC97_09570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FRC97_09575	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FRC97_09605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FRC97_09610	COG0131	Imidazoleglycerol-phosphate dehydratase
FRC97_09620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FRC97_09640	COG0438	transferase activity, transferring glycosyl groups
FRC97_09670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FRC97_09675	COG1301	dicarboxylic acid transport
FRC97_09685	COG0107	imidazoleglycerol-phosphate synthase activity
FRC97_09690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FRC97_09695	COG0140	phosphoribosyl-ATP diphosphatase activity
FRC97_09710	COG0537	adenosine 5'-monophosphoramidase activity
FRC97_09715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FRC97_09720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FRC97_09725	COG0805	protein transport
FRC97_09750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FRC97_09770	COG0714	Associated with various cellular activities
FRC97_09775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC97_09780	COG0084	hydrolase, TatD family'
FRC97_09790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FRC97_09795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FRC97_09845	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_09850	COG0840	transmembrane signaling receptor activity
FRC97_09855	COG0829	nickel cation binding
FRC97_09875	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FRC97_09900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_09905	COG1116	anion transmembrane transporter activity
FRC97_09920	COG0280	phosphate acetyltransferase
FRC97_09920	COG0281	malic enzyme
FRC97_09940	COG1953	Uracil, thiamine, allantoin
FRC97_09945	COG2186	Transcriptional regulator
FRC97_09950	COG0840	transmembrane signaling receptor activity
FRC97_09955	COG1301	dicarboxylic acid transport
FRC97_09985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FRC97_10000	COG2186	Transcriptional regulator
FRC97_10010	COG0405	Gamma-glutamyltransferase
FRC97_10050	COG0251	oxidation-reduction process
FRC97_10070	COG3447	MASE1 domain protein
FRC97_10070	COG5001	Diguanylate cyclase
FRC97_10070	COG5002	protein histidine kinase activity
FRC97_10080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_10100	COG3845	ABC transporter
FRC97_10105	COG4603	Belongs to the binding-protein-dependent transport system permease family
FRC97_10130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FRC97_10140	COG2366	antibiotic biosynthetic process
FRC97_10145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FRC97_10160	COG0717	Belongs to the dCTP deaminase family
FRC97_10175	COG2321	neutral zinc metallopeptidase
FRC97_10180	COG0513	Belongs to the DEAD box helicase family
FRC97_10185	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FRC97_10190	COG2916	Histone family protein nucleoid-structuring protein H-NS
FRC97_10195	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FRC97_10225	COG3483	tryptophan 2,3-dioxygenase activity
FRC97_10235	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FRC97_10240	COG1522	sequence-specific DNA binding
FRC97_10245	COG0727	PFAM Uncharacterised protein family (UPF0153)
FRC97_10270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FRC97_10275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FRC97_10285	COG0579	oxidoreductase
FRC97_10290	COG0268	Binds directly to 16S ribosomal RNA
FRC97_10295	COG0728	peptidoglycan biosynthetic process
FRC97_10305	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FRC97_10305	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FRC97_10315	COG3022	response to hydroperoxide
FRC97_10320	COG1530	ribonuclease E activity
FRC97_10345	COG0616	signal peptide processing
FRC97_10345	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FRC97_10350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FRC97_10355	COG0424	maF-like protein
FRC97_10360	COG1399	metal-binding, possibly nucleic acid-binding protein
FRC97_10365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FRC97_10370	COG0416	fatty acid biosynthetic process
FRC97_10375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FRC97_10380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FRC97_10385	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_10390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FRC97_10395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FRC97_10420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC97_10425	COG0481	GTPase activity
FRC97_10430	COG0681	Belongs to the peptidase S26 family
FRC97_10440	COG0571	ribonuclease III activity
FRC97_10445	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FRC97_10450	COG1381	Involved in DNA repair and RecF pathway recombination
FRC97_10455	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FRC97_10460	COG1472	Belongs to the glycosyl hydrolase 3 family
FRC97_10465	COG3064	Membrane
FRC97_10475	COG2203	Gaf domain
FRC97_10475	COG3706	GGDEF domain
FRC97_10475	COG4251	negative regulation of phosphorylation
FRC97_10475	COG5001	Diguanylate cyclase
FRC97_10480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FRC97_10505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FRC97_10520	COG0762	integral membrane protein
FRC97_10525	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FRC97_10530	COG0159	tryptophan synthase activity
FRC97_10535	COG0133	tryptophan synthase activity
FRC97_10540	COG0135	phosphoribosylanthranilate isomerase activity
FRC97_10545	COG0101	tRNA pseudouridine synthase activity
FRC97_10555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FRC97_10565	COG0473	3-isopropylmalate dehydrogenase activity
FRC97_10570	COG0066	3-isopropylmalate dehydratase activity
FRC97_10580	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FRC97_10590	COG0484	heat shock protein binding
FRC97_10595	COG0443	Heat shock 70 kDa protein
FRC97_10600	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FRC97_10605	COG0360	Binds together with S18 to 16S ribosomal RNA
FRC97_10615	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FRC97_10620	COG0359	binds to the 23S rRNA
FRC97_10635	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FRC97_10640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRC97_10650	COG0436	Aminotransferase
FRC97_10665	COG1763	Mo-molybdopterin cofactor biosynthetic process
FRC97_10670	COG0303	'Molybdopterin
FRC97_10675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FRC97_10680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC97_10705	COG0314	molybdopterin synthase activity
FRC97_10710	COG0542	response to heat
FRC97_10730	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FRC97_10740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC97_10745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC97_10755	COG0436	Aminotransferase
FRC97_10760	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FRC97_10765	COG1185	polyribonucleotide nucleotidyltransferase activity
FRC97_10770	COG3321	synthase
FRC97_10770	COG0604	alcohol dehydrogenase
FRC97_10770	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_10775	COG0149	triose-phosphate isomerase activity
FRC97_10790	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC97_10795	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC97_10800	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC97_10805	COG0649	NAD binding
FRC97_10810	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FRC97_10815	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FRC97_10820	COG1034	ATP synthesis coupled electron transport
FRC97_10825	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FRC97_10830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC97_10840	COG0713	ATP synthesis coupled electron transport
FRC97_10855	COG1007	ATP synthesis coupled electron transport
FRC97_10870	COG1132	(ABC) transporter
FRC97_10915	COG0457	Tetratricopeptide repeat
FRC97_10915	COG0463	Glycosyl transferase, family 2
FRC97_10935	COG0071	Belongs to the small heat shock protein (HSP20) family
FRC97_10940	COG1136	(ABC) transporter
FRC97_10945	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FRC97_10950	COG0702	epimerase
FRC97_10955	COG1733	regulation of RNA biosynthetic process
FRC97_10960	COG2267	carboxylic ester hydrolase activity
FRC97_10965	COG0584	glycerophosphoryl diester phosphodiesterase
FRC97_10975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FRC97_10980	COG0586	Pfam SNARE associated Golgi protein
FRC97_10985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC97_11000	COG0860	N-Acetylmuramoyl-L-alanine amidase
FRC97_11005	COG0802	atpase or kinase
FRC97_11010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FRC97_11040	COG4974	Belongs to the 'phage' integrase family
FRC97_11045	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_11050	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FRC97_11055	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FRC97_11060	COG2833	Protein of unknown function (DUF455)
FRC97_11070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FRC97_11080	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FRC97_11085	COG0148	phosphopyruvate hydratase activity
FRC97_11105	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FRC97_11110	COG0504	CTP synthase activity
FRC97_11115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FRC97_11120	COG0756	dUTP diphosphatase activity
FRC97_11130	COG1047	Peptidyl-prolyl cis-trans
FRC97_11135	COG2850	peptidyl-arginine hydroxylation
FRC97_11150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FRC97_11155	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FRC97_11160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC97_11180	COG0741	lytic transglycosylase activity
FRC97_11190	COG0840	transmembrane signaling receptor activity
FRC97_11195	COG0840	transmembrane signaling receptor activity
FRC97_11200	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FRC97_11240	COG2308	Evidence 4 Homologs of previously reported genes of
FRC97_11260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FRC97_11270	COG4628	conserved protein (DUF2132)
FRC97_11280	COG0657	acetylesterase activity
FRC97_11285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC97_11310	COG4774	siderophore transport
FRC97_11355	COG3634	alkyl hydroperoxide reductase activity
FRC97_11380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FRC97_11395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FRC97_11420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_11435	COG0583	DNA-binding transcription factor activity
FRC97_11440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC97_11450	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_11455	COG4948	Mandelate Racemase Muconate Lactonizing
FRC97_11500	COG0840	transmembrane signaling receptor activity
FRC97_11505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FRC97_11510	COG0358	DNA primase activity
FRC97_11515	COG5001	Diguanylate cyclase
FRC97_11515	COG3300	MHYT domain
FRC97_11520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_11525	COG0405	Gamma-glutamyltransferase
FRC97_11530	COG3540	Alkaline phosphatase
FRC97_11540	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_11540	COG3321	synthase
FRC97_11540	COG0604	alcohol dehydrogenase
FRC97_11545	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FRC97_11550	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FRC97_11560	COG0564	pseudouridine synthase activity
FRC97_11565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FRC97_11570	COG1187	pseudouridine synthase activity
FRC97_11575	COG0105	UTP biosynthetic process
FRC97_11580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FRC97_11585	COG3063	Type IV pilus biogenesis stability protein PilW
FRC97_11595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FRC97_11600	COG0124	histidyl-tRNA synthetase
FRC97_11615	COG1160	GTP binding
FRC97_11620	COG1923	regulation of RNA biosynthetic process
FRC97_11625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FRC97_11630	COG0330	HflC and HflK could
FRC97_11635	COG0330	HflC and HflK could
FRC97_11640	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FRC97_11645	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FRC97_11650	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FRC97_11680	COG1187	pseudouridine synthase activity
FRC97_11710	COG0174	glutamine synthetase
FRC97_11720	COG3852	Histidine kinase
FRC97_11735	COG0708	Exodeoxyribonuclease III
FRC97_11750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FRC97_11760	COG0277	FAD linked oxidase domain protein
FRC97_11770	COG1295	ribonuclease BN
FRC97_11775	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FRC97_11800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FRC97_11805	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FRC97_11810	COG0740	serine-type endopeptidase activity
FRC97_11815	COG0544	peptidyl-prolyl cis-trans isomerase activity
FRC97_11825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC97_11835	COG1562	ergosterol biosynthetic process
FRC97_11865	COG0631	protein serine/threonine phosphatase activity
FRC97_11880	COG2885	chlorophyll binding
FRC97_11945	COG1451	nucleotide metabolic process
FRC97_11950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_11955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FRC97_11960	COG2080	2 iron, 2 sulfur cluster binding
FRC97_11965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FRC97_11980	COG0114	fumarate hydratase activity
FRC97_11990	COG0745	RESPONSE REGULATOR receiver
FRC97_11995	COG2205	protein histidine kinase activity
FRC97_12000	COG2113	Glycine betaine
FRC97_12005	COG4176	ABC-type proline glycine betaine transport system permease component
FRC97_12010	COG4175	Glycine betaine
FRC97_12020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FRC97_12045	COG4654	Cytochrome c, class I
FRC97_12055	COG0129	dihydroxy-acid dehydratase activity
FRC97_12070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FRC97_12075	COG1802	Transcriptional regulator
FRC97_12100	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_12110	COG0589	response to stress
FRC97_12120	COG2217	Heavy metal translocating P-type atpase
FRC97_12130	COG3278	Belongs to the heme-copper respiratory oxidase family
FRC97_12165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FRC97_12170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FRC97_12180	COG3437	response regulator, receiver
FRC97_12200	COG4206	TonB-dependent receptor
FRC97_12205	COG1797	cobyrinic acid a,c-diamide synthase activity
FRC97_12220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FRC97_12225	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FRC97_12230	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FRC97_12235	COG0778	Nitroreductase
FRC97_12240	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FRC97_12270	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_12275	COG1492	cobalamin metabolic process
FRC97_12280	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FRC97_12305	COG0477	Major facilitator Superfamily
FRC97_12325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FRC97_12330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC97_12335	COG2900	Belongs to the SlyX family
FRC97_12350	COG0513	Belongs to the DEAD box helicase family
FRC97_12375	COG1959	2 iron, 2 sulfur cluster binding
FRC97_12380	COG0583	DNA-binding transcription factor activity
FRC97_12395	COG0560	Phosphoserine phosphatase
FRC97_12405	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FRC97_12415	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FRC97_12420	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FRC97_12420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FRC97_12425	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FRC97_12425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FRC97_12445	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_12455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FRC97_12490	COG0693	protein deglycase activity
FRC97_12500	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FRC97_12505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FRC97_12525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FRC97_12540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_12545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC97_12565	COG1446	asparaginase
FRC97_12570	COG4172	Belongs to the ABC transporter superfamily
FRC97_12580	COG0601	transmembrane transport
FRC97_12585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC97_12605	COG0322	excinuclease ABC activity
FRC97_12770	COG0737	Belongs to the 5'-nucleotidase family
FRC97_12795	COG1193	negative regulation of DNA recombination
FRC97_12815	COG2003	Belongs to the UPF0758 family
FRC97_12820	COG1047	Peptidyl-prolyl cis-trans
FRC97_12825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FRC97_12830	COG1253	flavin adenine dinucleotide binding
FRC97_12835	COG0617	tRNA 3'-terminal CCA addition
FRC97_12835	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FRC97_12835	COG0517	IMP dehydrogenase activity
FRC97_12840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC97_12845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FRC97_12890	COG0129	dihydroxy-acid dehydratase activity
FRC97_12905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_12910	COG0765	amino acid transport
FRC97_12915	COG0765	amino acid transport
FRC97_12920	COG0612	Peptidase, M16
FRC97_12930	COG3209	COG3209 Rhs family protein
FRC97_12965	COG0038	chloride channel
FRC97_13010	COG0443	Heat shock 70 kDa protein
FRC97_13070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FRC97_13075	COG4774	siderophore transport
FRC97_13085	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FRC97_13150	COG3209	COG3209 Rhs family protein
FRC97_13155	COG0180	Tryptophanyl-tRNA synthetase
FRC97_13160	COG1994	Peptidase M50
FRC97_13170	COG0009	L-threonylcarbamoyladenylate synthase
FRC97_13175	COG0613	PHP domain protein
FRC97_13180	COG0738	Major facilitator superfamily
FRC97_13195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FRC97_13205	COG4591	ABC-type transport system involved in lipoprotein release permease component
FRC97_13215	COG1136	(ABC) transporter
FRC97_13220	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FRC97_13225	COG1970	mechanosensitive ion channel activity
FRC97_13230	COG0723	plastoquinol--plastocyanin reductase activity
FRC97_13235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FRC97_13240	COG2857	Cytochrome c1
FRC97_13245	COG0625	glutathione transferase activity
FRC97_13250	COG2969	positive regulation of protein catabolic process
FRC97_13265	COG0739	heme binding
FRC97_13270	COG0653	protein targeting
FRC97_13275	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FRC97_13285	COG0494	nUDIX hydrolase
FRC97_13290	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FRC97_13295	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FRC97_13300	COG0237	dephospho-CoA kinase activity
FRC97_13320	COG0583	DNA-binding transcription factor activity
FRC97_13330	COG1473	amidohydrolase
FRC97_13340	COG0142	geranyltranstransferase activity
FRC97_13345	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FRC97_13350	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FRC97_13355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FRC97_13360	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FRC97_13365	COG0494	nUDIX hydrolase
FRC97_13370	COG0442	prolyl-tRNA aminoacylation
FRC97_13380	COG1253	flavin adenine dinucleotide binding
FRC97_13385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FRC97_13390	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FRC97_13400	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FRC97_13405	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FRC97_13445	COG1511	domain protein
FRC97_13445	COG3264	Mechanosensitive ion channel
FRC97_13450	COG0584	glycerophosphoryl diester phosphodiesterase
FRC97_13460	COG3842	ATPase activity
FRC97_13465	COG0395	ABC-type sugar transport system, permease component
FRC97_13470	COG1175	transmembrane transport
FRC97_13475	COG1653	transport
FRC97_13480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC97_13505	COG2226	methyltransferase
FRC97_13520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FRC97_13540	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FRC97_13550	COG0494	nUDIX hydrolase
FRC97_13555	COG0745	RESPONSE REGULATOR receiver
FRC97_13565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC97_13570	COG0302	gtp cyclohydrolase
FRC97_13600	COG1609	Transcriptional regulator
FRC97_13630	COG0747	negative chemotaxis
FRC97_13640	COG4608	Belongs to the ABC transporter superfamily
FRC97_13645	COG0444	Belongs to the ABC transporter superfamily
FRC97_13650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC97_13660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FRC97_13665	COG0193	aminoacyl-tRNA hydrolase activity
FRC97_13670	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FRC97_13675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FRC97_13685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FRC97_13700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FRC97_13710	COG1194	a g-specific adenine glycosylase
FRC97_13715	COG1660	Displays ATPase and GTPase activities
FRC97_13720	COG0497	DNA recombination
FRC97_13725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FRC97_13780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FRC97_13785	COG1420	regulation of RNA biosynthetic process
FRC97_13795	COG2197	response regulator
FRC97_13800	COG3693	PFAM glycoside hydrolase, family 10
FRC97_13830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FRC97_13835	COG1758	RNA polymerase activity
FRC97_13840	COG0194	GDP metabolic process
FRC97_13845	COG1561	YicC-like family, N-terminal region
FRC97_13865	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FRC97_13870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FRC97_13885	COG4221	oxidoreductase activity
FRC97_13890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC97_13905	COG1595	DNA-templated transcription, initiation
FRC97_13930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC97_13935	COG4191	Histidine kinase
FRC97_13935	COG0784	Response regulator, receiver
FRC97_13980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FRC97_13980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FRC97_14005	COG4968	Prepilin-type N-terminal cleavage methylation domain
FRC97_14010	COG4968	Prepilin-type N-terminal cleavage methylation domain
FRC97_14050	COG2205	protein histidine kinase activity
FRC97_14055	COG2249	NAD(P)H dehydrogenase (quinone) activity
FRC97_14080	COG0464	growth
FRC97_14095	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FRC97_14100	COG0830	nickel cation binding
FRC97_14105	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FRC97_14115	COG0804	urea catabolic process
FRC97_14120	COG0832	Belongs to the urease beta subunit family
FRC97_14130	COG0831	urea catabolic process
FRC97_14145	COG5001	Diguanylate cyclase
FRC97_14170	COG1304	FMN binding
FRC97_14175	COG2205	protein histidine kinase activity
FRC97_14195	COG2814	Major facilitator Superfamily
FRC97_14200	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FRC97_14205	COG4336	lyase activity
FRC97_14210	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FRC97_14215	COG4770	biotin carboxylase activity
FRC97_14230	COG3038	cytochrome b561
FRC97_14250	COG5599	Phosphatase
FRC97_14255	COG1301	dicarboxylic acid transport
FRC97_14305	COG2814	Major facilitator Superfamily
FRC97_14405	COG0697	spore germination
FRC97_14440	COG0583	DNA-binding transcription factor activity
FRC97_14455	COG1283	sodium-dependent phosphate transmembrane transporter activity
FRC97_14465	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FRC97_14470	COG3842	ATPase activity
FRC97_14475	COG1177	transmembrane transport
FRC97_14480	COG4149	molybdate abc transporter
FRC97_14490	COG1609	Transcriptional regulator
FRC97_14500	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FRC97_14510	COG0196	riboflavin kinase activity
FRC97_14520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_14530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC97_14535	COG0840	transmembrane signaling receptor activity
FRC97_14540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC97_14560	COG1960	acyl-CoA dehydrogenase activity
FRC97_14565	COG3132	Protein of unknown function, DUF480
FRC97_14570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FRC97_14585	COG3866	Pectate lyase
FRC97_14590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FRC97_14590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC97_14605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC97_14610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FRC97_14615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FRC97_14620	COG0492	ferredoxin-NADP+ reductase activity
FRC97_14625	COG1674	ftsk spoiiie
FRC97_14630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FRC97_14645	COG1573	uracil-dna glycosylase
FRC97_14650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FRC97_14655	COG0840	transmembrane signaling receptor activity
FRC97_14660	COG0559	Belongs to the binding-protein-dependent transport system permease family
FRC97_14680	COG2885	chlorophyll binding
FRC97_14680	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FRC97_14685	COG1392	Phosphate transport regulator
FRC97_14690	COG0306	phosphate transporter
FRC97_14705	COG0228	four-way junction DNA binding
FRC97_14710	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FRC97_14715	COG0336	Belongs to the RNA methyltransferase TrmD family
FRC97_14720	COG0335	large ribosomal subunit rRNA binding
FRC97_14730	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FRC97_14735	COG1162	GTPase activity
FRC97_14740	COG2154	pterin-4-alpha-carbinolamine dehydratase
FRC97_14750	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FRC97_14755	COG0513	Belongs to the DEAD box helicase family
FRC97_14760	COG3447	MASE1 domain protein
FRC97_14760	COG5002	protein histidine kinase activity
FRC97_14760	COG5001	Diguanylate cyclase
FRC97_14765	COG2814	Major facilitator Superfamily
FRC97_14780	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FRC97_14785	COG5002	protein histidine kinase activity
FRC97_14790	COG2204	response regulator
FRC97_14840	COG0516	GMP reductase activity
FRC97_14925	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FRC97_14965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_14970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_15000	COG0412	Dienelactone hydrolase
FRC97_15010	COG0165	Argininosuccinate lyase
FRC97_15020	COG3275	phosphorelay sensor kinase activity
FRC97_15025	COG0165	Argininosuccinate lyase
FRC97_15060	COG0840	transmembrane signaling receptor activity
FRC97_15065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC97_15075	COG1304	FMN binding
FRC97_15080	COG0840	transmembrane signaling receptor activity
FRC97_15100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FRC97_15130	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FRC97_15135	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FRC97_15145	COG0617	tRNA 3'-terminal CCA addition
FRC97_15185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_15190	COG1960	acyl-CoA dehydrogenase activity
FRC97_15195	COG0583	DNA-binding transcription factor activity
FRC97_15235	COG2816	NAD+ diphosphatase activity
FRC97_15240	COG0425	Belongs to the sulfur carrier protein TusA family
FRC97_15250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FRC97_15255	COG0525	valine-tRNA ligase activity
FRC97_15260	COG0501	Belongs to the peptidase M48B family
FRC97_15270	COG0488	(ABC) transporter
FRC97_15290	COG0181	hydroxymethylbilane synthase activity
FRC97_15295	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FRC97_15305	COG0628	permease
FRC97_15360	COG1722	exodeoxyribonuclease VII activity
FRC97_15365	COG0142	geranyltranstransferase activity
FRC97_15370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FRC97_15375	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FRC97_15395	COG0668	transmembrane transport
FRC97_15400	COG0366	Alpha amylase catalytic
FRC97_15405	COG0366	Alpha amylase catalytic
FRC97_15410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FRC97_15415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FRC97_15420	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FRC97_15440	COG2005	Transcriptional regulator
FRC97_15440	COG3585	molybdate ion transport
FRC97_15460	COG1280	lysine exporter protein (LysE YggA)
FRC97_15465	COG3279	Response regulator of the LytR AlgR family
FRC97_15470	COG3275	phosphorelay sensor kinase activity
FRC97_15500	COG1968	undecaprenyl-diphosphatase activity
FRC97_15505	COG5002	protein histidine kinase activity
FRC97_15505	COG3447	MASE1 domain protein
FRC97_15505	COG5001	Diguanylate cyclase
FRC97_15530	COG3209	COG3209 Rhs family protein
FRC97_15545	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FRC97_15550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FRC97_15605	COG5002	protein histidine kinase activity
FRC97_15605	COG0784	Response regulator, receiver
FRC97_15605	COG2205	protein histidine kinase activity
FRC97_15610	COG3437	response regulator, receiver
FRC97_15620	COG1132	(ABC) transporter
FRC97_15635	COG0483	inositol monophosphate 1-phosphatase activity
FRC97_15650	COG4555	ABC transporter
FRC97_15665	COG1045	serine acetyltransferase
FRC97_15670	COG0521	Mo-molybdopterin cofactor biosynthetic process
FRC97_15675	COG3028	Belongs to the UPF0307 family
FRC97_15680	COG0312	modulator of DNA gyrase
FRC97_15695	COG2721	sulfolactate sulfo-lyase activity
FRC97_15710	COG0477	Major facilitator Superfamily
FRC97_15715	COG1752	Esterase of the alpha-beta hydrolase superfamily
FRC97_15720	COG0473	3-isopropylmalate dehydrogenase activity
FRC97_15725	COG0583	DNA-binding transcription factor activity
FRC97_15735	COG0625	glutathione transferase activity
FRC97_15740	COG1610	YqeY-like protein
FRC97_15745	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FRC97_15765	COG0640	Transcriptional regulator
FRC97_15770	COG2081	HI0933 family
FRC97_15785	COG0288	reversible hydration of carbon dioxide
FRC97_15790	COG1607	acyl-coa hydrolase
FRC97_15795	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FRC97_15795	COG5297	Belongs to the glycosyl hydrolase family 6
FRC97_15805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FRC97_15810	COG0243	molybdopterin cofactor binding
FRC97_15820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FRC97_15825	COG0840	transmembrane signaling receptor activity
FRC97_15840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC97_15850	COG0840	transmembrane signaling receptor activity
FRC97_15855	COG0516	GMP reductase activity
FRC97_15855	COG0517	IMP dehydrogenase activity
FRC97_15875	COG2198	Histidine kinase
FRC97_15875	COG0643	Histidine kinase
FRC97_15880	COG0840	transmembrane signaling receptor activity
FRC97_15890	COG0745	RESPONSE REGULATOR receiver
FRC97_15905	COG2223	nitrite transmembrane transporter activity
FRC97_15910	COG3959	Transketolase, thiamine diphosphate binding domain
FRC97_15915	COG3958	Transketolase
FRC97_15920	COG0194	GDP metabolic process
FRC97_15935	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FRC97_15950	COG0626	cystathionine gamma-synthase activity
FRC97_15960	COG0724	RNA recognition motif
FRC97_15975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FRC97_15980	COG1116	anion transmembrane transporter activity
FRC97_15985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_15990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FRC97_16010	COG0683	leucine binding
FRC97_16015	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FRC97_16030	COG0683	leucine binding
FRC97_16060	COG2951	lytic endotransglycosylase activity
FRC97_16075	COG0714	Associated with various cellular activities
FRC97_16080	COG0123	including yeast histone deacetylase and acetoin utilization protein
FRC97_16085	COG1024	Enoyl-CoA hydratase
FRC97_16155	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FRC97_16180	COG3048	D-serine ammonia-lyase activity
FRC97_16185	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_16190	COG0154	amidase activity
FRC97_16210	COG1739	Uncharacterized protein family UPF0029
FRC97_16225	COG0840	transmembrane signaling receptor activity
FRC97_16240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_16250	COG0556	nucleotide-excision repair
FRC97_16255	COG1959	2 iron, 2 sulfur cluster binding
FRC97_16260	COG1104	cysteine desulfurase activity
FRC97_16265	COG0822	iron-sulfur transferase activity
FRC97_16275	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FRC97_16280	COG0443	Heat shock 70 kDa protein
FRC97_16285	COG0633	Ferredoxin
FRC97_16310	COG0579	oxidoreductase
FRC97_16330	COG0167	dihydroorotate dehydrogenase activity
FRC97_16335	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FRC97_16350	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FRC97_16355	COG4566	intracellular signal transduction
FRC97_16365	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FRC97_16370	COG0508	dehydrogenase complex catalyzes the overall conversion of
FRC97_16375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FRC97_16400	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FRC97_16405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC97_16415	COG0515	serine threonine protein kinase
FRC97_16445	COG3243	poly(R)-hydroxyalkanoic acid synthase
FRC97_16450	COG0183	Belongs to the thiolase family
FRC97_16455	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_16460	COG0488	(ABC) transporter
FRC97_16465	COG2890	protein-(glutamine-N5) methyltransferase activity
FRC97_16470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FRC97_16480	COG2171	N-acyltransferase activity
FRC97_16490	COG0840	transmembrane signaling receptor activity
FRC97_16495	COG2878	Part of a membrane complex involved in electron transport
FRC97_16515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC97_16530	COG3039	Transposase
FRC97_16545	COG0840	transmembrane signaling receptor activity
FRC97_16610	COG1802	Transcriptional regulator
FRC97_16615	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FRC97_16615	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FRC97_16625	COG1703	isobutyryl-CoA mutase activity
FRC97_16630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FRC97_16640	COG4770	biotin carboxylase activity
FRC97_16660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FRC97_16750	COG5002	protein histidine kinase activity
FRC97_16765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC97_16780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FRC97_16785	COG0583	DNA-binding transcription factor activity
FRC97_16790	COG2814	Major facilitator Superfamily
FRC97_16800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FRC97_16805	COG2011	ABC-type metal ion transport system permease component
FRC97_16825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FRC97_16845	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FRC97_16850	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FRC97_16855	COG4208	sulfate ABC transporter
FRC97_16860	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FRC97_16865	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FRC97_16870	COG1054	Belongs to the UPF0176 family
FRC97_16885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FRC97_16885	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FRC97_16890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_16900	COG1643	Atp-dependent helicase
FRC97_16910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FRC97_16915	COG0252	asparaginase activity
FRC97_16925	COG0563	adenylate kinase activity
FRC97_16930	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FRC97_16935	COG2835	tetraacyldisaccharide 4'-kinase activity
FRC97_16940	COG1663	tetraacyldisaccharide 4'-kinase activity
FRC97_16945	COG0848	biopolymer transport protein
FRC97_16950	COG0811	peptide transport
FRC97_16955	COG1570	exodeoxyribonuclease VII activity
FRC97_16960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FRC97_16990	COG0625	glutathione transferase activity
FRC97_16995	COG1942	4-Oxalocrotonate Tautomerase
FRC97_17010	COG2814	Major facilitator Superfamily
FRC97_17015	COG0789	Transcriptional regulator
FRC97_17055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC97_17060	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_17070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FRC97_17080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_17095	COG2721	sulfolactate sulfo-lyase activity
FRC97_17110	COG4772	TonB-dependent receptor
FRC97_17115	COG2032	superoxide dismutase activity
FRC97_17130	COG1960	acyl-CoA dehydrogenase activity
FRC97_17155	COG1113	amino acid transport
FRC97_17165	COG0505	Belongs to the CarA family
FRC97_17170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FRC97_17175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FRC97_17190	COG1534	Rna-binding protein
FRC97_17195	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FRC97_17200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FRC97_17210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FRC97_17240	COG0248	Ppx GppA phosphatase
FRC97_17245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FRC97_17250	COG0573	inorganic phosphate transmembrane transporter activity
FRC97_17255	COG0581	inorganic phosphate transmembrane transporter activity
FRC97_17260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FRC97_17265	COG0704	Plays a role in the regulation of phosphate uptake
FRC97_17280	COG0534	Mate efflux family protein
FRC97_17290	COG0254	rRNA binding
FRC97_17295	COG0420	3'-5' exonuclease activity
FRC97_17300	COG0419	ATPase involved in DNA repair
FRC97_17305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FRC97_17320	COG1074	ATP-dependent DNA helicase activity
FRC97_17325	COG2081	HI0933 family
FRC97_17340	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FRC97_17345	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FRC97_17350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FRC97_17370	COG0741	lytic transglycosylase activity
FRC97_17370	COG1388	LysM domain
FRC97_17375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FRC97_17430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FRC97_17435	COG2226	methyltransferase
FRC97_17440	COG0328	RNA-DNA hybrid ribonuclease activity
FRC97_17455	COG0303	'Molybdopterin
FRC97_17465	COG0746	molybdenum cofactor guanylyltransferase activity
FRC97_17470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FRC97_17495	COG1012	belongs to the aldehyde dehydrogenase family
FRC97_17520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FRC97_17535	COG0587	DNA-directed DNA polymerase activity
FRC97_17540	COG2982	Protein involved in outer membrane biogenesis
FRC97_17545	COG0564	pseudouridine synthase activity
FRC97_17575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FRC97_17585	COG0431	NADPH-dependent FMN reductase
FRC97_17590	COG0583	DNA-binding transcription factor activity
FRC97_17630	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_17635	COG0346	lactoylglutathione lyase activity
FRC97_17645	COG0800	Aldolase
FRC97_17655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_17660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC97_17665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC97_17670	COG3265	gluconokinase activity
FRC97_17675	COG1609	Transcriptional regulator
FRC97_17700	COG0259	pyridoxamine-phosphate oxidase activity
FRC97_17715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_17720	COG4771	TonB-dependent receptor
FRC97_17745	COG1136	(ABC) transporter
FRC97_17755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FRC97_17760	COG1309	transcriptional regulator
FRC97_17780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FRC97_17780	COG0045	succinate-CoA ligase (ADP-forming) activity
FRC97_17780	COG1042	CoA-binding domain protein
FRC97_17830	COG2133	pyrroloquinoline quinone binding
FRC97_17835	COG0791	NLP P60 protein
FRC97_17880	COG3209	COG3209 Rhs family protein
FRC97_17935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FRC97_17950	COG4128	Pfam Zonular occludens toxin
FRC97_18005	COG0527	aspartate kinase activity
FRC97_18010	COG0037	tRNA processing
FRC97_18025	COG0215	cysteine-tRNA ligase activity
FRC97_18080	COG1522	sequence-specific DNA binding
FRC97_18100	COG3384	dioxygenase
FRC97_18115	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FRC97_18125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC97_18140	COG1309	transcriptional regulator
FRC97_18180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC97_18210	COG0840	transmembrane signaling receptor activity
FRC97_18240	COG0564	pseudouridine synthase activity
FRC97_18245	COG1285	pathogenesis
FRC97_18260	COG2814	Major facilitator Superfamily
FRC97_18280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FRC97_18295	COG5002	protein histidine kinase activity
FRC97_18310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FRC97_18320	COG2918	glutathione biosynthetic process
FRC97_18330	COG3386	PFAM SMP-30 Gluconolaconase
FRC97_18350	COG1879	ABC-type sugar transport system periplasmic component
FRC97_18355	COG4213	ABC transporter substrate-binding protein
FRC97_18365	COG4214	carbohydrate transport
FRC97_18375	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC97_18380	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC97_18400	COG3734	2-keto-3-deoxy-galactonokinase
FRC97_18405	COG0800	Aldolase
FRC97_18410	COG4948	Mandelate Racemase Muconate Lactonizing
FRC97_18415	COG1289	transmembrane transporter activity
FRC97_18435	COG2201	protein-glutamate methylesterase activity
FRC97_18440	COG0745	RESPONSE REGULATOR receiver
FRC97_18450	COG2202	Pas domain
FRC97_18450	COG2205	protein histidine kinase activity
FRC97_18475	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FRC97_18480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC97_18485	COG0436	Aminotransferase
FRC97_18490	COG0824	Thioesterase
FRC97_18510	COG0477	Major facilitator Superfamily
FRC97_18515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FRC97_18520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FRC97_18525	COG1845	cytochrome c oxidase, subunit III
FRC97_18530	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FRC97_18555	COG0583	DNA-binding transcription factor activity
FRC97_18560	COG0826	peptidase U32
FRC97_18575	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FRC97_18580	COG1049	propionate catabolic process, 2-methylcitrate cycle
FRC97_18595	COG4106	trans-aconitate 2-methyltransferase activity
FRC97_18600	COG0039	L-malate dehydrogenase activity
FRC97_18605	COG2188	Transcriptional regulator
FRC97_18620	COG1053	succinate dehydrogenase
FRC97_18625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FRC97_18630	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FRC97_18635	COG0372	Belongs to the citrate synthase family
FRC97_18645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FRC97_18650	COG4977	sequence-specific DNA binding
FRC97_18660	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FRC97_18665	COG2194	sulfuric ester hydrolase activity
FRC97_18675	COG0473	3-isopropylmalate dehydrogenase activity
FRC97_18685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC97_18690	COG0601	transmembrane transport
FRC97_18700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_18720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC97_18730	COG1522	sequence-specific DNA binding
FRC97_18735	COG1473	amidohydrolase
FRC97_18780	COG1960	acyl-CoA dehydrogenase activity
FRC97_18795	COG3264	Mechanosensitive ion channel
FRC97_18795	COG1511	domain protein
FRC97_18810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FRC97_18820	COG1196	nuclear chromosome segregation
FRC97_18830	COG1742	UPF0060 membrane protein
FRC97_18840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FRC97_18845	COG1132	(ABC) transporter
FRC97_18870	COG0789	Transcriptional regulator
FRC97_18875	COG0776	regulation of translation
FRC97_18880	COG0072	phenylalanine-tRNA ligase activity
FRC97_18880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC97_18885	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FRC97_18890	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FRC97_18895	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FRC97_18900	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FRC97_18905	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FRC97_18910	COG2224	Isocitrate lyase
FRC97_18925	COG1522	sequence-specific DNA binding
FRC97_18935	COG1840	ABC-type Fe3 transport system, periplasmic component
FRC97_18955	COG2153	protein acetylation
FRC97_18960	COG2130	NADP-dependent
FRC97_18980	COG1960	acyl-CoA dehydrogenase activity
FRC97_18985	COG2050	protein possibly involved in aromatic compounds catabolism
FRC97_18990	COG0183	Belongs to the thiolase family
FRC97_18995	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC97_18995	COG1024	Enoyl-CoA hydratase
FRC97_19245	COG3706	GGDEF domain
FRC97_19270	COG0411	ABC transporter
FRC97_19280	COG0559	Belongs to the binding-protein-dependent transport system permease family
FRC97_19290	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_19295	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FRC97_19300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FRC97_19305	COG2917	probably involved in intracellular septation
FRC97_19315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC97_19335	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FRC97_19340	COG0688	phosphatidylethanolamine metabolic process
FRC97_19355	COG5006	permease, DMT superfamily
FRC97_19370	COG1228	amidohydrolase
FRC97_19385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FRC97_19390	COG2986	histidine ammonia-lyase
FRC97_19395	COG2188	Transcriptional regulator
FRC97_19405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_19415	COG1366	Belongs to the anti-sigma-factor antagonist family
FRC97_19420	COG1366	Belongs to the anti-sigma-factor antagonist family
FRC97_19425	COG2172	sigma factor antagonist activity
FRC97_19435	COG2205	protein histidine kinase activity
FRC97_19440	COG2205	protein histidine kinase activity
FRC97_19445	COG4191	Histidine kinase
FRC97_19445	COG0784	Response regulator, receiver
FRC97_19465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FRC97_19485	COG0297	glycogen (starch) synthase activity
FRC97_19495	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_19500	COG0557	exoribonuclease II activity
FRC97_19525	COG0741	lytic transglycosylase activity
FRC97_19530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FRC97_19535	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FRC97_19545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FRC97_19550	COG0517	IMP dehydrogenase activity
FRC97_19550	COG1125	glycine betaine transport
FRC97_19565	COG1011	Hydrolase
FRC97_19570	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FRC97_19575	COG5002	protein histidine kinase activity
FRC97_19625	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_19635	COG0642	Histidine kinase
FRC97_19650	COG0667	Aldo Keto reductase
FRC97_19655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FRC97_19660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FRC97_19665	COG4181	ATPase activity
FRC97_19705	COG1054	Belongs to the UPF0176 family
FRC97_19710	COG1741	Belongs to the pirin family
FRC97_19720	COG1741	Belongs to the pirin family
FRC97_19725	COG0583	DNA-binding transcription factor activity
FRC97_19735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC97_19740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FRC97_19750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FRC97_19775	COG0583	DNA-binding transcription factor activity
FRC97_19785	COG1116	anion transmembrane transporter activity
FRC97_19790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_19800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FRC97_19810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FRC97_19820	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FRC97_19825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_19825	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FRC97_19845	COG0730	response to heat
FRC97_19860	COG0175	sulfate reduction
FRC97_19865	COG0529	Catalyzes the synthesis of activated sulfate
FRC97_19865	COG2895	sulfate adenylyltransferase (ATP) activity
FRC97_19870	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FRC97_19875	COG0492	ferredoxin-NADP+ reductase activity
FRC97_19920	COG0351	phosphomethylpyrimidine kinase
FRC97_19935	COG2022	thiamine diphosphate biosynthetic process
FRC97_19950	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC97_19955	COG1024	Enoyl-CoA hydratase
FRC97_19970	COG1960	acyl-CoA dehydrogenase activity
FRC97_19985	COG1619	proteins homologs of microcin C7 resistance protein MccF
FRC97_20010	COG0826	peptidase U32
FRC97_20020	COG0823	Involved in the tonB-independent uptake of proteins
FRC97_20020	COG1506	peptidase
FRC97_20020	COG4946	Tricorn protease homolog
FRC97_20030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FRC97_20035	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FRC97_20050	COG3047	cAMP biosynthetic process
FRC97_20055	COG2354	Protein conserved in bacteria
FRC97_20060	COG3300	MHYT domain
FRC97_20060	COG5001	Diguanylate cyclase
FRC97_20075	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FRC97_20075	COG0047	phosphoribosylformylglycinamidine synthase activity
FRC97_20080	COG0024	Methionine aminopeptidase
FRC97_20085	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FRC97_20090	COG0242	peptide deformylase activity
FRC97_20095	COG2832	Protein of unknown function (DUF454)
FRC97_20110	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FRC97_20115	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FRC97_20120	COG1414	Transcriptional regulator
FRC97_20130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC97_20135	COG1183	phosphatidylcholine synthase activity
FRC97_20140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FRC97_20145	COG0440	acetolactate synthase activity
FRC97_20150	COG0028	Belongs to the TPP enzyme family
FRC97_20155	COG1595	DNA-templated transcription, initiation
FRC97_20175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FRC97_20185	COG0347	Belongs to the P(II) protein family
FRC97_20200	COG0583	DNA-binding transcription factor activity
FRC97_20210	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_20215	COG0835	chemotaxis
FRC97_20240	COG1252	NADH dehydrogenase
FRC97_20250	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FRC97_20285	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_20305	COG4120	Belongs to the binding-protein-dependent transport system permease family
FRC97_20320	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FRC97_20325	COG0509	glycine decarboxylation via glycine cleavage system
FRC97_20330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FRC97_20330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FRC97_20335	COG0545	Peptidyl-prolyl cis-trans isomerase
FRC97_20345	COG0564	pseudouridine synthase activity
FRC97_20350	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_20375	COG0589	response to stress
FRC97_20415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FRC97_20435	COG0583	DNA-binding transcription factor activity
FRC97_20440	COG0436	Aminotransferase
FRC97_20475	COG0683	leucine binding
FRC97_20485	COG1960	acyl-CoA dehydrogenase activity
FRC97_20490	COG1024	Enoyl-CoA hydratase
FRC97_20500	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_20515	COG0596	Alpha beta hydrolase
FRC97_20530	COG3593	DNA synthesis involved in DNA repair
FRC97_20570	COG1530	ribonuclease E activity
FRC97_20575	COG0424	maF-like protein
FRC97_20585	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FRC97_20590	COG0799	negative regulation of ribosome biogenesis
FRC97_20595	COG0408	coproporphyrinogen oxidase activity
FRC97_20600	COG0151	Belongs to the GarS family
FRC97_20605	COG0217	transcriptional regulatory protein
FRC97_20610	COG0433	COG0433 Predicted ATPase
FRC97_20630	COG0277	FAD linked oxidase domain protein
FRC97_20635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FRC97_20660	COG0625	glutathione transferase activity
FRC97_20675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FRC97_20695	COG0402	S-adenosylhomocysteine deaminase activity
FRC97_20730	COG0484	heat shock protein binding
FRC97_20735	COG1012	belongs to the aldehyde dehydrogenase family
FRC97_20755	COG3284	Transcriptional regulator
FRC97_20765	COG2925	Exonuclease
FRC97_20770	COG2951	lytic endotransglycosylase activity
FRC97_20775	COG0542	response to heat
FRC97_20780	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FRC97_20795	COG1199	ATP-dependent helicase activity
FRC97_20810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FRC97_20815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FRC97_20820	COG0508	dehydrogenase complex catalyzes the overall conversion of
FRC97_20825	COG0567	Dehydrogenase, E1 component
FRC97_20830	COG0628	permease
FRC97_20835	COG5002	protein histidine kinase activity
FRC97_20835	COG5001	Diguanylate cyclase
FRC97_20835	COG3447	MASE1 domain protein
FRC97_20840	COG4172	Belongs to the ABC transporter superfamily
FRC97_20845	COG4239	(ABC) transporter, permease
FRC97_20850	COG4174	ABC transporter (Permease)
FRC97_20855	COG4166	transmembrane transport
FRC97_20865	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FRC97_20980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC97_20995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FRC97_21000	COG1605	Chorismate mutase
FRC97_21000	COG0077	Prephenate dehydratase
FRC97_21005	COG0287	Prephenate dehydrogenase
FRC97_21010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FRC97_21020	COG0776	regulation of translation
FRC97_21030	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FRC97_21035	COG2111	Na H antiporter
FRC97_21035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FRC97_21040	COG1006	Multisubunit Na H antiporter MnhC subunit
FRC97_21045	COG0651	ATP synthesis coupled electron transport
FRC97_21055	COG2212	antiporter activity
FRC97_21090	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FRC97_21115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FRC97_21120	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FRC97_21125	COG0405	Gamma-glutamyltransferase
FRC97_21165	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FRC97_21170	COG0670	Belongs to the BI1 family
FRC97_21180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FRC97_21195	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FRC97_21195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FRC97_21195	COG0506	proline dehydrogenase activity
FRC97_21205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FRC97_21215	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FRC97_21220	COG4774	siderophore transport
FRC97_21255	COG0494	nUDIX hydrolase
FRC97_21260	COG1278	Cold shock
FRC97_21275	COG0492	ferredoxin-NADP+ reductase activity
FRC97_21280	COG2226	methyltransferase
FRC97_21320	COG3209	COG3209 Rhs family protein
FRC97_21345	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_21355	COG0583	DNA-binding transcription factor activity
FRC97_21385	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FRC97_21425	COG0582	viral genome integration into host DNA
FRC97_21430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FRC97_21430	COG0519	Catalyzes the synthesis of GMP from XMP
FRC97_21455	COG2914	Belongs to the UPF0125 (RnfH) family
FRC97_21465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FRC97_21485	COG1024	Enoyl-CoA hydratase
FRC97_21490	COG1253	flavin adenine dinucleotide binding
FRC97_21500	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FRC97_21505	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FRC97_21510	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FRC97_21515	COG0195	Participates in both transcription termination and antitermination
FRC97_21520	COG0779	Required for maturation of 30S ribosomal subunits
FRC97_21530	COG2010	Cytochrome c
FRC97_21530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_21600	COG2423	ornithine cyclodeaminase activity
FRC97_21620	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FRC97_21630	COG2885	chlorophyll binding
FRC97_21635	COG0823	Involved in the tonB-independent uptake of proteins
FRC97_21640	COG1132	(ABC) transporter
FRC97_21650	COG0084	hydrolase, TatD family'
FRC97_21665	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FRC97_21670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FRC97_21685	COG0657	acetylesterase activity
FRC97_21695	COG1454	alcohol dehydrogenase
FRC97_21710	COG2183	response to ionizing radiation
FRC97_21735	COG2814	Major facilitator Superfamily
FRC97_21740	COG2814	Major facilitator Superfamily
FRC97_21780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC97_21795	COG1286	toxin biosynthetic process
FRC97_21805	COG0285	dihydrofolate synthase activity
FRC97_21810	COG1393	Belongs to the ArsC family
FRC97_21820	COG3123	guanosine phosphorylase activity
FRC97_21825	COG0137	argininosuccinate synthase activity
FRC97_21835	COG1666	GTP binding
FRC97_21840	COG3577	Aspartyl protease
FRC97_21850	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FRC97_21855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FRC97_21860	COG0667	Aldo Keto reductase
FRC97_21865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FRC97_21880	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FRC97_21890	COG0308	aminopeptidase N
FRC97_21895	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FRC97_21905	COG0583	DNA-binding transcription factor activity
FRC97_21910	COG1960	acyl-CoA dehydrogenase activity
FRC97_21915	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_21920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_21925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FRC97_21930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FRC97_21935	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC97_21940	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC97_21945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FRC97_21950	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC97_21965	COG0750	zinc metalloprotease
FRC97_21970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FRC97_21975	COG0575	Belongs to the CDS family
FRC97_21985	COG0233	cytoplasmic translational termination
FRC97_21990	COG0528	UMP kinase activity
FRC97_21995	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FRC97_22000	COG0052	Belongs to the universal ribosomal protein uS2 family
FRC97_22005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_22010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FRC97_22010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FRC97_22035	COG0789	Transcriptional regulator
FRC97_22065	COG2132	Multicopper oxidase
FRC97_22095	COG3191	aminopeptidase activity
FRC97_22110	COG0488	(ABC) transporter
FRC97_22115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FRC97_22120	COG0513	Belongs to the DEAD box helicase family
FRC97_22130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FRC97_22130	COG4651	solute:proton antiporter activity
FRC97_22160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FRC97_22170	COG2207	Transcriptional regulator
FRC97_22175	COG1012	belongs to the aldehyde dehydrogenase family
FRC97_22225	COG2267	carboxylic ester hydrolase activity
FRC97_22245	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_22250	COG0028	Belongs to the TPP enzyme family
FRC97_22255	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_22265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FRC97_22475	COG3728	DNA packaging
FRC97_22475	COG5484	DNA packaging
FRC97_22595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FRC97_22610	COG0534	Mate efflux family protein
FRC97_22615	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_22640	COG2771	luxR family
FRC97_22645	COG3916	Acyl-homoserine-lactone synthase
FRC97_22655	COG1802	Transcriptional regulator
FRC97_22665	COG0154	amidase activity