locus-tag	class	description
Dtpsy_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Dtpsy_0005	COG0456	acetyltransferase
Dtpsy_0007	COG1764	response to oxidative stress
Dtpsy_0009	COG1254	Belongs to the acylphosphatase family
Dtpsy_0014	COG1199	ATP-dependent helicase activity
Dtpsy_0019	COG0791	NLP P60 protein
Dtpsy_0020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Dtpsy_0026	COG2974	May be involved in recombination
Dtpsy_0027	COG1301	dicarboxylic acid transport
Dtpsy_0028	COG0784	Response regulator, receiver
Dtpsy_0028	COG2205	protein histidine kinase activity
Dtpsy_0028	COG2198	Histidine kinase
Dtpsy_0030	COG0700	Nucleoside recognition
Dtpsy_0032	COG0183	Belongs to the thiolase family
Dtpsy_0035	COG0789	Transcriptional regulator
Dtpsy_0038	COG0840	transmembrane signaling receptor activity
Dtpsy_0042	COG0625	glutathione transferase activity
Dtpsy_0045	COG0445	tRNA wobble uridine modification
Dtpsy_0046	COG0357	Ribosomal RNA small subunit methyltransferase G
Dtpsy_0048	COG1192	Involved in chromosome partitioning
Dtpsy_0050	COG1475	DNA binding
Dtpsy_0056	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
Dtpsy_0057	COG0655	NAD(P)H dehydrogenase (quinone) activity
Dtpsy_0058	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Dtpsy_0061	COG0277	FAD linked oxidase domain protein
Dtpsy_0063	COG2096	Adenosyltransferase
Dtpsy_0064	COG2050	protein possibly involved in aromatic compounds catabolism
Dtpsy_0068	COG2233	PERMEase
Dtpsy_0071	COG2199	diguanylate cyclase activity
Dtpsy_0071	COG2203	Gaf domain
Dtpsy_0072	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Dtpsy_0074	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Dtpsy_0076	COG0583	DNA-binding transcription factor activity
Dtpsy_0079	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_0083	COG1183	phosphatidylcholine synthase activity
Dtpsy_0084	COG0850	regulation of cytokinetic process
Dtpsy_0086	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Dtpsy_0087	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Dtpsy_0089	COG0683	leucine binding
Dtpsy_0090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Dtpsy_0091	COG0583	DNA-binding transcription factor activity
Dtpsy_0097	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Dtpsy_0099	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Dtpsy_0100	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_0103	COG0514	ATP-dependent DNA helicase (RecQ)
Dtpsy_0109	COG3256	nitric oxide reductase
Dtpsy_0110	COG3604	Transcriptional regulator
Dtpsy_0112	COG1760	l-serine dehydratase
Dtpsy_0114	COG3181	Tripartite tricarboxylate transporter family receptor
Dtpsy_0115	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_0122	COG0183	Belongs to the thiolase family
Dtpsy_0124	COG1024	Enoyl-CoA hydratase
Dtpsy_0126	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_0136	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_0137	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
Dtpsy_0138	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_0139	COG2030	dehydratase
Dtpsy_0140	COG1024	Enoyl-CoA hydratase
Dtpsy_0141	COG0427	acetyl-CoA hydrolase
Dtpsy_0142	COG0183	Belongs to the thiolase family
Dtpsy_0144	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_0148	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_0151	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Dtpsy_0153	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Dtpsy_0154	COG2326	polyphosphate kinase activity
Dtpsy_0155	COG0583	DNA-binding transcription factor activity
Dtpsy_0157	COG0583	DNA-binding transcription factor activity
Dtpsy_0163	COG0723	plastoquinol--plastocyanin reductase activity
Dtpsy_0164	COG2204	response regulator
Dtpsy_0166	COG2989	Protein conserved in bacteria
Dtpsy_0167	COG3108	Peptidase M15
Dtpsy_0168	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Dtpsy_0172	COG0683	leucine binding
Dtpsy_0174	COG0411	ABC transporter
Dtpsy_0176	COG0583	DNA-binding transcription factor activity
Dtpsy_0177	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_0181	COG0347	Belongs to the P(II) protein family
Dtpsy_0182	COG0004	ammonium transporteR
Dtpsy_0184	COG0277	FAD linked oxidase domain protein
Dtpsy_0186	COG0247	lactate metabolic process
Dtpsy_0191	COG0386	Belongs to the glutathione peroxidase family
Dtpsy_0193	COG0477	Major facilitator Superfamily
Dtpsy_0194	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Dtpsy_0196	COG1858	cytochrome C peroxidase
Dtpsy_0197	COG0625	glutathione transferase activity
Dtpsy_0204	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Dtpsy_0206	COG3307	-O-antigen
Dtpsy_0209	COG0477	Major facilitator Superfamily
Dtpsy_0210	COG2258	MOSC domain
Dtpsy_0212	COG2205	protein histidine kinase activity
Dtpsy_0213	COG0745	RESPONSE REGULATOR receiver
Dtpsy_0220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Dtpsy_0224	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_0227	COG0708	Exodeoxyribonuclease III
Dtpsy_0228	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Dtpsy_0230	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Dtpsy_0231	COG0154	amidase activity
Dtpsy_0232	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Dtpsy_0233	COG1077	Cell shape determining protein MreB Mrl
Dtpsy_0235	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Dtpsy_0236	COG0768	penicillin binding
Dtpsy_0238	COG1126	abc transporter atp-binding protein
Dtpsy_0239	COG0765	amino acid transport
Dtpsy_0240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Dtpsy_0244	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Dtpsy_0245	COG1127	ABC transporter
Dtpsy_0249	COG3237	CsbD-like
Dtpsy_0252	COG2203	Gaf domain
Dtpsy_0252	COG3706	GGDEF domain
Dtpsy_0252	COG5001	Diguanylate cyclase
Dtpsy_0252	COG4251	negative regulation of phosphorylation
Dtpsy_0253	COG2095	MarC family integral membrane protein
Dtpsy_0254	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_0255	COG0412	Dienelactone hydrolase
Dtpsy_0257	COG1566	PFAM secretion protein HlyD family protein
Dtpsy_0258	COG1538	Outer membrane efflux protein
Dtpsy_0259	COG1846	Transcriptional regulator
Dtpsy_0260	COG0598	Magnesium transport protein CorA
Dtpsy_0266	COG2945	thiolester hydrolase activity
Dtpsy_0267	COG1686	Belongs to the peptidase S11 family
Dtpsy_0268	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Dtpsy_0269	COG0049	tRNA binding
Dtpsy_0270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Dtpsy_0271	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Dtpsy_0272	COG0051	transcription antitermination factor activity, RNA binding
Dtpsy_0273	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Dtpsy_0274	COG0088	Forms part of the polypeptide exit tunnel
Dtpsy_0275	COG0089	rRNA binding
Dtpsy_0276	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Dtpsy_0277	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Dtpsy_0278	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Dtpsy_0279	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Dtpsy_0280	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Dtpsy_0281	COG0255	Belongs to the universal ribosomal protein uL29 family
Dtpsy_0282	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Dtpsy_0283	COG0678	peroxiredoxin activity
Dtpsy_0287	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Dtpsy_0291	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Dtpsy_0292	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Dtpsy_0293	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Dtpsy_0294	COG0321	lipoyl(octanoyl) transferase activity
Dtpsy_0295	COG2921	Belongs to the UPF0250 family
Dtpsy_0297	COG0356	it plays a direct role in the translocation of protons across the membrane
Dtpsy_0299	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Dtpsy_0300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Dtpsy_0301	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Dtpsy_0302	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Dtpsy_0303	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Dtpsy_0304	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Dtpsy_0305	COG1793	dna ligase
Dtpsy_0305	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Dtpsy_0306	COG1793	dna ligase
Dtpsy_0307	COG1201	RNA secondary structure unwinding
Dtpsy_0315	COG3245	cytochrome
Dtpsy_0316	COG1538	Outer membrane efflux protein
Dtpsy_0317	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Dtpsy_0318	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Dtpsy_0322	COG1063	alcohol dehydrogenase
Dtpsy_0324	COG0121	glutamine amidotransferase
Dtpsy_0325	COG1942	4-Oxalocrotonate Tautomerase
Dtpsy_0327	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Dtpsy_0332	COG0018	arginyl-trna synthetase
Dtpsy_0334	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Dtpsy_0336	COG1137	ATPase activity
Dtpsy_0337	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Dtpsy_0342	COG3012	SEC-C Motif Domain Protein
Dtpsy_0342	COG3318	Belongs to the UPF0149 family
Dtpsy_0343	COG1058	Belongs to the CinA family
Dtpsy_0343	COG1546	Belongs to the CinA family
Dtpsy_0344	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Dtpsy_0346	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Dtpsy_0349	COG2967	ApaG domain
Dtpsy_0350	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Dtpsy_0352	COG0546	phosphoglycolate phosphatase activity
Dtpsy_0353	COG0840	transmembrane signaling receptor activity
Dtpsy_0354	COG0840	transmembrane signaling receptor activity
Dtpsy_0359	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Dtpsy_0361	COG0134	indole-3-glycerol-phosphate synthase activity
Dtpsy_0362	COG3706	GGDEF domain
Dtpsy_0363	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Dtpsy_0365	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Dtpsy_0367	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Dtpsy_0369	COG0783	Belongs to the Dps family
Dtpsy_0371	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Dtpsy_0373	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Dtpsy_0375	COG3842	ATPase activity
Dtpsy_0376	COG3842	ATPase activity
Dtpsy_0379	COG0395	ABC-type sugar transport system, permease component
Dtpsy_0382	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Dtpsy_0383	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Dtpsy_0384	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Dtpsy_0385	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Dtpsy_0386	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Dtpsy_0387	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Dtpsy_0388	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Dtpsy_0389	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Dtpsy_0390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Dtpsy_0391	COG1841	ribosomal large subunit assembly
Dtpsy_0392	COG0200	Binds to the 23S rRNA
Dtpsy_0393	COG0201	protein transport
Dtpsy_0394	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Dtpsy_0395	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Dtpsy_0396	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Dtpsy_0397	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Dtpsy_0398	COG0202	RNA polymerase activity
Dtpsy_0399	COG0203	ribosomal protein L17
Dtpsy_0402	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Dtpsy_0403	COG0463	Glycosyl transferase, family 2
Dtpsy_0406	COG0792	nuclease activity
Dtpsy_0407	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Dtpsy_0408	COG2823	Periplasmic or secreted lipoprotein
Dtpsy_0409	COG2084	Dehydrogenase
Dtpsy_0411	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Dtpsy_0413	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Dtpsy_0415	COG2733	membrane
Dtpsy_0417	COG0277	FAD linked oxidase domain protein
Dtpsy_0418	COG0583	DNA-binding transcription factor activity
Dtpsy_0423	COG3850	Histidine kinase
Dtpsy_0424	COG2197	response regulator
Dtpsy_0426	COG2223	nitrite transmembrane transporter activity
Dtpsy_0427	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Dtpsy_0428	COG1140	nitrate reductase beta subunit
Dtpsy_0429	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Dtpsy_0430	COG2181	nitrate reductase activity
Dtpsy_0436	COG3945	hemerythrin HHE cation binding domain
Dtpsy_0442	COG0243	molybdopterin cofactor binding
Dtpsy_0444	COG1473	amidohydrolase
Dtpsy_0448	COG2818	Glycosylase
Dtpsy_0451	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Dtpsy_0459	COG0559	Belongs to the binding-protein-dependent transport system permease family
Dtpsy_0460	COG0411	ABC transporter
Dtpsy_0461	COG1022	Amp-dependent synthetase and ligase
Dtpsy_0462	COG3267	Type II secretory pathway component ExeA
Dtpsy_0462	COG3409	Peptidoglycan-binding domain 1 protein
Dtpsy_0464	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Dtpsy_0465	COG1187	pseudouridine synthase activity
Dtpsy_0466	COG0326	Molecular chaperone. Has ATPase activity
Dtpsy_0467	COG3181	Tripartite tricarboxylate transporter family receptor
Dtpsy_0473	COG1764	response to oxidative stress
Dtpsy_0474	COG1846	Transcriptional regulator
Dtpsy_0476	COG1250	3-hydroxyacyl-CoA dehydrogenase
Dtpsy_0482	COG0842	Transport permease protein
Dtpsy_0485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Dtpsy_0487	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Dtpsy_0488	COG1490	D-aminoacyl-tRNA deacylase activity
Dtpsy_0489	COG0513	Belongs to the DEAD box helicase family
Dtpsy_0490	COG0730	response to heat
Dtpsy_0491	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Dtpsy_0492	COG1702	phosphate starvation-inducible protein PhoH
Dtpsy_0493	COG0632	four-way junction helicase activity
Dtpsy_0495	COG0443	Heat shock 70 kDa protein
Dtpsy_0497	COG0443	Heat shock 70 kDa protein
Dtpsy_0499	COG2255	four-way junction helicase activity
Dtpsy_0505	COG0037	tRNA processing
Dtpsy_0511	COG2175	clavaminate synthase activity
Dtpsy_0513	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Dtpsy_0514	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Dtpsy_0517	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Dtpsy_0518	COG3387	PFAM Glycoside hydrolase 15-related
Dtpsy_0519	COG1877	trehalose-phosphatase activity
Dtpsy_0521	COG0617	tRNA 3'-terminal CCA addition
Dtpsy_0523	COG0625	glutathione transferase activity
Dtpsy_0524	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Dtpsy_0528	COG3128	pkhd-type hydroxylase
Dtpsy_0530	COG4774	siderophore transport
Dtpsy_0531	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Dtpsy_0532	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_0534	COG3186	Phenylalanine-4-hydroxylase
Dtpsy_0537	COG1522	sequence-specific DNA binding
Dtpsy_0539	COG4535	Mg2 and Co2 transporter CorC
Dtpsy_0540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Dtpsy_0541	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Dtpsy_0543	COG0752	glycyl-tRNA synthetase alpha subunit
Dtpsy_0544	COG0751	glycine-tRNA ligase activity
Dtpsy_0545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Dtpsy_0546	COG0204	Acyl-transferase
Dtpsy_0549	COG1652	LysM domain
Dtpsy_0550	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Dtpsy_0554	COG1091	dTDP-4-dehydrorhamnose reductase activity
Dtpsy_0557	COG0438	transferase activity, transferring glycosyl groups
Dtpsy_0560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Dtpsy_0561	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Dtpsy_0562	COG0438	transferase activity, transferring glycosyl groups
Dtpsy_0562	COG1216	Glycosyl transferase, family 2
Dtpsy_0563	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Dtpsy_0566	COG0662	Cupin 2, conserved barrel domain protein
Dtpsy_0566	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Dtpsy_0568	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Dtpsy_0569	COG1309	transcriptional regulator
Dtpsy_0571	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_0573	COG1250	3-hydroxyacyl-CoA dehydrogenase
Dtpsy_0573	COG1024	Enoyl-CoA hydratase
Dtpsy_0574	COG0183	Belongs to the thiolase family
Dtpsy_0577	COG1024	Enoyl-CoA hydratase
Dtpsy_0578	COG2050	protein possibly involved in aromatic compounds catabolism
Dtpsy_0580	COG1607	acyl-coa hydrolase
Dtpsy_0581	COG5265	(ABC) transporter
Dtpsy_0583	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Dtpsy_0585	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Dtpsy_0586	COG0583	DNA-binding transcription factor activity
Dtpsy_0588	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Dtpsy_0589	COG0765	amino acid transport
Dtpsy_0590	COG0765	amino acid transport
Dtpsy_0591	COG1126	abc transporter atp-binding protein
Dtpsy_0592	COG2423	ornithine cyclodeaminase activity
Dtpsy_0593	COG1522	sequence-specific DNA binding
Dtpsy_0594	COG2010	Cytochrome c
Dtpsy_0596	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Dtpsy_0597	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Dtpsy_0599	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Dtpsy_0601	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Dtpsy_0602	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Dtpsy_0604	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Dtpsy_0605	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Dtpsy_0608	COG0316	Belongs to the HesB IscA family
Dtpsy_0609	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Dtpsy_0613	COG0583	DNA-binding transcription factor activity
Dtpsy_0615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Dtpsy_0616	COG4191	Histidine kinase
Dtpsy_0619	COG1522	sequence-specific DNA binding
Dtpsy_0620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Dtpsy_0624	COG1064	alcohol dehydrogenase
Dtpsy_0625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Dtpsy_0627	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Dtpsy_0629	COG2205	protein histidine kinase activity
Dtpsy_0632	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_0633	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Dtpsy_0634	COG3045	CreA protein
Dtpsy_0636	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Dtpsy_0636	COG0189	ligase activity
Dtpsy_0637	COG1132	(ABC) transporter
Dtpsy_0643	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Dtpsy_0657	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Dtpsy_0658	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Dtpsy_0659	COG1765	OsmC-like protein
Dtpsy_0660	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
Dtpsy_0663	COG4166	transmembrane transport
Dtpsy_0665	COG1473	amidohydrolase
Dtpsy_0667	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Dtpsy_0668	COG0444	Belongs to the ABC transporter superfamily
Dtpsy_0669	COG4608	Belongs to the ABC transporter superfamily
Dtpsy_0670	COG0737	Belongs to the 5'-nucleotidase family
Dtpsy_0671	COG1881	PFAM PEBP family protein
Dtpsy_0673	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Dtpsy_0674	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Dtpsy_0675	COG0166	Belongs to the GPI family
Dtpsy_0676	COG3706	GGDEF domain
Dtpsy_0677	COG0459	protein refolding
Dtpsy_0678	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Dtpsy_0679	COG1051	belongs to the nudix hydrolase family
Dtpsy_0679	COG1056	cytidyltransferase-related domain
Dtpsy_0683	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Dtpsy_0685	COG1560	Kdo2-lipid A biosynthetic process
Dtpsy_0689	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Dtpsy_0691	COG1333	cytochrome c biogenesis protein
Dtpsy_0692	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Dtpsy_0693	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Dtpsy_0694	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Dtpsy_0697	COG1965	Belongs to the frataxin family
Dtpsy_0705	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Dtpsy_0709	COG0070	glutamate synthase
Dtpsy_0709	COG0067	glutamate synthase
Dtpsy_0709	COG0069	glutamate synthase activity
Dtpsy_0712	COG0765	amino acid transport
Dtpsy_0714	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Dtpsy_0715	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Dtpsy_0716	COG1127	ABC transporter
Dtpsy_0717	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Dtpsy_0718	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Dtpsy_0722	COG1131	(ABC) transporter
Dtpsy_0723	COG0842	Transport permease protein
Dtpsy_0724	COG5007	Belongs to the BolA IbaG family
Dtpsy_0725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Dtpsy_0726	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Dtpsy_0729	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Dtpsy_0730	COG0131	Imidazoleglycerol-phosphate dehydratase
Dtpsy_0732	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Dtpsy_0737	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Dtpsy_0738	COG0107	imidazoleglycerol-phosphate synthase activity
Dtpsy_0739	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Dtpsy_0740	COG0140	phosphoribosyl-ATP diphosphatase activity
Dtpsy_0743	COG0537	adenosine 5'-monophosphoramidase activity
Dtpsy_0744	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Dtpsy_0745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Dtpsy_0746	COG0805	protein transport
Dtpsy_0747	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Dtpsy_0749	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Dtpsy_0750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Dtpsy_0751	COG1970	mechanosensitive ion channel activity
Dtpsy_0752	COG0723	plastoquinol--plastocyanin reductase activity
Dtpsy_0753	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Dtpsy_0754	COG2857	Cytochrome c1
Dtpsy_0755	COG0625	glutathione transferase activity
Dtpsy_0756	COG2969	positive regulation of protein catabolic process
Dtpsy_0758	COG0739	heme binding
Dtpsy_0759	COG0653	protein targeting
Dtpsy_0762	COG0494	nUDIX hydrolase
Dtpsy_0763	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Dtpsy_0764	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Dtpsy_0765	COG0237	dephospho-CoA kinase activity
Dtpsy_0769	COG0142	geranyltranstransferase activity
Dtpsy_0770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Dtpsy_0771	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Dtpsy_0772	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Dtpsy_0773	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Dtpsy_0774	COG0494	nUDIX hydrolase
Dtpsy_0775	COG0442	prolyl-tRNA aminoacylation
Dtpsy_0776	COG0741	lytic transglycosylase activity
Dtpsy_0777	COG1253	flavin adenine dinucleotide binding
Dtpsy_0778	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Dtpsy_0780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Dtpsy_0781	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Dtpsy_0783	COG0583	DNA-binding transcription factor activity
Dtpsy_0786	COG3264	Mechanosensitive ion channel
Dtpsy_0786	COG1511	domain protein
Dtpsy_0787	COG0584	glycerophosphoryl diester phosphodiesterase
Dtpsy_0789	COG0395	ABC-type sugar transport system, permease component
Dtpsy_0790	COG1175	transmembrane transport
Dtpsy_0791	COG1653	transport
Dtpsy_0792	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Dtpsy_0796	COG2226	methyltransferase
Dtpsy_0799	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Dtpsy_0803	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Dtpsy_0807	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Dtpsy_0808	COG0302	gtp cyclohydrolase
Dtpsy_0815	COG0154	amidase activity
Dtpsy_0817	COG4608	Belongs to the ABC transporter superfamily
Dtpsy_0818	COG0444	Belongs to the ABC transporter superfamily
Dtpsy_0819	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Dtpsy_0821	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Dtpsy_0822	COG0193	aminoacyl-tRNA hydrolase activity
Dtpsy_0823	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Dtpsy_0824	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Dtpsy_0825	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Dtpsy_0828	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Dtpsy_0831	COG1660	Displays ATPase and GTPase activities
Dtpsy_0832	COG0497	DNA recombination
Dtpsy_0833	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Dtpsy_0846	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Dtpsy_0847	COG1420	regulation of RNA biosynthetic process
Dtpsy_0849	COG0251	oxidation-reduction process
Dtpsy_0856	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Dtpsy_0857	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Dtpsy_0861	COG1561	YicC-like family, N-terminal region
Dtpsy_0862	COG0194	GDP metabolic process
Dtpsy_0863	COG1758	RNA polymerase activity
Dtpsy_0864	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Dtpsy_0867	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Dtpsy_0868	COG1185	polyribonucleotide nucleotidyltransferase activity
Dtpsy_0870	COG0149	triose-phosphate isomerase activity
Dtpsy_0872	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Dtpsy_0873	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Dtpsy_0874	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Dtpsy_0875	COG0649	NAD binding
Dtpsy_0878	COG1034	ATP synthesis coupled electron transport
Dtpsy_0879	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Dtpsy_0880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Dtpsy_0882	COG0713	ATP synthesis coupled electron transport
Dtpsy_0885	COG1007	ATP synthesis coupled electron transport
Dtpsy_0888	COG1132	(ABC) transporter
Dtpsy_0890	COG4133	protoheme IX ABC transporter activity
Dtpsy_0891	COG1280	lysine exporter protein (LysE YggA)
Dtpsy_0892	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Dtpsy_0893	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Dtpsy_0895	COG0586	Pfam SNARE associated Golgi protein
Dtpsy_0898	COG0860	N-Acetylmuramoyl-L-alanine amidase
Dtpsy_0899	COG0802	atpase or kinase
Dtpsy_0900	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Dtpsy_0902	COG3181	Tripartite tricarboxylate transporter family receptor
Dtpsy_0903	COG4974	Belongs to the 'phage' integrase family
Dtpsy_0905	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Dtpsy_0906	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Dtpsy_0907	COG2833	Protein of unknown function (DUF455)
Dtpsy_0909	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Dtpsy_0911	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Dtpsy_0912	COG0148	phosphopyruvate hydratase activity
Dtpsy_0914	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Dtpsy_0915	COG0504	CTP synthase activity
Dtpsy_0916	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Dtpsy_0917	COG0756	dUTP diphosphatase activity
Dtpsy_0919	COG1047	Peptidyl-prolyl cis-trans
Dtpsy_0920	COG2850	peptidyl-arginine hydroxylation
Dtpsy_0922	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Dtpsy_0923	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Dtpsy_0924	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Dtpsy_0927	COG2814	Major facilitator Superfamily
Dtpsy_0929	COG0741	lytic transglycosylase activity
Dtpsy_0931	COG0840	transmembrane signaling receptor activity
Dtpsy_0934	COG2308	Evidence 4 Homologs of previously reported genes of
Dtpsy_0938	COG4628	conserved protein (DUF2132)
Dtpsy_0945	COG4774	siderophore transport
Dtpsy_0954	COG1722	exodeoxyribonuclease VII activity
Dtpsy_0955	COG0142	geranyltranstransferase activity
Dtpsy_0956	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Dtpsy_0957	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Dtpsy_0958	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Dtpsy_0960	COG0405	Gamma-glutamyltransferase
Dtpsy_0961	COG3437	response regulator, receiver
Dtpsy_0961	COG3850	Histidine kinase
Dtpsy_0961	COG4999	Histidine kinase
Dtpsy_0961	COG2205	protein histidine kinase activity
Dtpsy_0965	COG1045	serine acetyltransferase
Dtpsy_0967	COG1063	alcohol dehydrogenase
Dtpsy_0969	COG0521	Mo-molybdopterin cofactor biosynthetic process
Dtpsy_0970	COG3028	Belongs to the UPF0307 family
Dtpsy_0971	COG0312	modulator of DNA gyrase
Dtpsy_0975	COG0114	fumarate hydratase activity
Dtpsy_0977	COG0745	RESPONSE REGULATOR receiver
Dtpsy_0978	COG2205	protein histidine kinase activity
Dtpsy_0979	COG2113	Glycine betaine
Dtpsy_0980	COG4176	ABC-type proline glycine betaine transport system permease component
Dtpsy_0981	COG4175	Glycine betaine
Dtpsy_0983	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Dtpsy_0985	COG4654	Cytochrome c, class I
Dtpsy_0987	COG0129	dihydroxy-acid dehydratase activity
Dtpsy_0988	COG0129	dihydroxy-acid dehydratase activity
Dtpsy_0991	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Dtpsy_0992	COG1802	Transcriptional regulator
Dtpsy_0996	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_1000	COG3278	Belongs to the heme-copper respiratory oxidase family
Dtpsy_1007	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Dtpsy_1008	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Dtpsy_1012	COG4206	TonB-dependent receptor
Dtpsy_1013	COG1797	cobyrinic acid a,c-diamide synthase activity
Dtpsy_1016	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Dtpsy_1017	COG1120	ATPase activity
Dtpsy_1018	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Dtpsy_1022	COG4372	Transposase
Dtpsy_1026	COG3038	cytochrome b561
Dtpsy_1030	COG2814	Major facilitator Superfamily
Dtpsy_1033	COG0281	malic enzyme
Dtpsy_1033	COG0280	phosphate acetyltransferase
Dtpsy_1034	COG2233	PERMEase
Dtpsy_1038	COG2186	Transcriptional regulator
Dtpsy_1039	COG0583	DNA-binding transcription factor activity
Dtpsy_1046	COG1012	belongs to the aldehyde dehydrogenase family
Dtpsy_1049	COG0402	S-adenosylhomocysteine deaminase activity
Dtpsy_1050	COG0717	Belongs to the dCTP deaminase family
Dtpsy_1052	COG2321	neutral zinc metallopeptidase
Dtpsy_1053	COG0513	Belongs to the DEAD box helicase family
Dtpsy_1056	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Dtpsy_1059	COG3901	Regulator of nitric oxide reductase transcription
Dtpsy_1059	COG0348	domain, Protein
Dtpsy_1060	COG4263	nitrous-oxide reductase activity
Dtpsy_1062	COG3245	cytochrome
Dtpsy_1064	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Dtpsy_1065	COG2916	Histone family protein nucleoid-structuring protein H-NS
Dtpsy_1066	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Dtpsy_1070	COG3275	phosphorelay sensor kinase activity
Dtpsy_1072	COG1968	undecaprenyl-diphosphatase activity
Dtpsy_1074	COG2267	carboxylic ester hydrolase activity
Dtpsy_1076	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Dtpsy_1077	COG3540	Alkaline phosphatase
Dtpsy_1078	COG3706	GGDEF domain
Dtpsy_1078	COG0745	RESPONSE REGULATOR receiver
Dtpsy_1080	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Dtpsy_1081	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Dtpsy_1083	COG0564	pseudouridine synthase activity
Dtpsy_1084	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Dtpsy_1085	COG1187	pseudouridine synthase activity
Dtpsy_1086	COG0105	UTP biosynthetic process
Dtpsy_1087	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Dtpsy_1090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Dtpsy_1091	COG0124	histidyl-tRNA synthetase
Dtpsy_1094	COG1160	GTP binding
Dtpsy_1095	COG1923	regulation of RNA biosynthetic process
Dtpsy_1096	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Dtpsy_1097	COG0330	HflC and HflK could
Dtpsy_1098	COG0330	HflC and HflK could
Dtpsy_1100	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Dtpsy_1101	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Dtpsy_1105	COG0726	polysaccharide deacetylase
Dtpsy_1111	COG3852	Histidine kinase
Dtpsy_1112	COG2204	response regulator
Dtpsy_1114	COG0708	Exodeoxyribonuclease III
Dtpsy_1116	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Dtpsy_1117	COG0277	FAD linked oxidase domain protein
Dtpsy_1119	COG1295	ribonuclease BN
Dtpsy_1121	COG1562	ergosterol biosynthetic process
Dtpsy_1126	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Dtpsy_1127	COG0544	peptidyl-prolyl cis-trans isomerase activity
Dtpsy_1128	COG0740	serine-type endopeptidase activity
Dtpsy_1129	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Dtpsy_1130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Dtpsy_1136	COG0633	Ferredoxin
Dtpsy_1137	COG0789	Transcriptional regulator
Dtpsy_1139	COG0640	Transcriptional regulator
Dtpsy_1140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Dtpsy_1146	COG1937	Protein conserved in bacteria
Dtpsy_1147	COG2814	Major facilitator Superfamily
Dtpsy_1148	COG1230	cation diffusion facilitator family transporter
Dtpsy_1149	COG0640	Transcriptional regulator
Dtpsy_1151	COG2217	Heavy metal translocating P-type atpase
Dtpsy_1154	COG1538	Outer membrane efflux protein
Dtpsy_1156	COG2814	Major facilitator Superfamily
Dtpsy_1162	COG2186	Transcriptional regulator
Dtpsy_1185	COG0322	excinuclease ABC activity
Dtpsy_1187	COG0776	regulation of translation
Dtpsy_1188	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Dtpsy_1190	COG4372	Transposase
Dtpsy_1199	COG0513	Belongs to the DEAD box helicase family
Dtpsy_1200	COG0488	(ABC) transporter
Dtpsy_1203	COG3191	aminopeptidase activity
Dtpsy_1208	COG2132	Multicopper oxidase
Dtpsy_1215	COG0789	Transcriptional regulator
Dtpsy_1220	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Dtpsy_1221	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Dtpsy_1223	COG0052	Belongs to the universal ribosomal protein uS2 family
Dtpsy_1224	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Dtpsy_1225	COG0528	UMP kinase activity
Dtpsy_1226	COG0233	cytoplasmic translational termination
Dtpsy_1227	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Dtpsy_1228	COG0575	Belongs to the CDS family
Dtpsy_1229	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Dtpsy_1230	COG0750	zinc metalloprotease
Dtpsy_1233	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Dtpsy_1234	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Dtpsy_1235	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Dtpsy_1236	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Dtpsy_1237	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Dtpsy_1238	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Dtpsy_1240	COG0557	exoribonuclease II activity
Dtpsy_1243	COG2010	Cytochrome c
Dtpsy_1243	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Dtpsy_1245	COG0779	Required for maturation of 30S ribosomal subunits
Dtpsy_1246	COG0195	Participates in both transcription termination and antitermination
Dtpsy_1247	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Dtpsy_1248	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Dtpsy_1249	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Dtpsy_1252	COG1024	Enoyl-CoA hydratase
Dtpsy_1256	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Dtpsy_1257	COG2867	negative regulation of translational initiation
Dtpsy_1261	COG0519	Catalyzes the synthesis of GMP from XMP
Dtpsy_1261	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Dtpsy_1262	COG0582	viral genome integration into host DNA
Dtpsy_1273	COG2003	Belongs to the UPF0758 family
Dtpsy_1277	COG1475	DNA binding
Dtpsy_1289	COG1192	Involved in chromosome partitioning
Dtpsy_1294	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Dtpsy_1298	COG1611	Belongs to the LOG family
Dtpsy_1299	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Dtpsy_1302	COG0842	Transport permease protein
Dtpsy_1303	COG0842	Transport permease protein
Dtpsy_1304	COG1131	(ABC) transporter
Dtpsy_1305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Dtpsy_1307	COG1309	transcriptional regulator
Dtpsy_1310	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_1311	COG0589	response to stress
Dtpsy_1314	COG0583	DNA-binding transcription factor activity
Dtpsy_1317	COG3838	Conjugal transfer protein Trbc
Dtpsy_1319	COG3451	type IV secretory pathway VirB4
Dtpsy_1322	COG3846	protein secretion by the type IV secretion system
Dtpsy_1325	COG2948	multi-organism process
Dtpsy_1338	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_1339	COG2918	glutathione biosynthetic process
Dtpsy_1341	COG0583	DNA-binding transcription factor activity
Dtpsy_1343	COG0798	PFAM Bile acid sodium symporter
Dtpsy_1350	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Dtpsy_1354	COG1285	pathogenesis
Dtpsy_1355	COG0564	pseudouridine synthase activity
Dtpsy_1368	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Dtpsy_1370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Dtpsy_1371	COG1322	Protein conserved in bacteria
Dtpsy_1373	COG1611	Belongs to the LOG family
Dtpsy_1374	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Dtpsy_1382	COG2212	antiporter activity
Dtpsy_1384	COG0651	ATP synthesis coupled electron transport
Dtpsy_1385	COG1006	Multisubunit Na H antiporter MnhC subunit
Dtpsy_1386	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Dtpsy_1386	COG2111	Na H antiporter
Dtpsy_1388	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Dtpsy_1390	COG0776	regulation of translation
Dtpsy_1392	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Dtpsy_1393	COG0287	Prephenate dehydrogenase
Dtpsy_1394	COG1605	Chorismate mutase
Dtpsy_1394	COG0077	Prephenate dehydratase
Dtpsy_1395	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Dtpsy_1398	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Dtpsy_1401	COG4372	Transposase
Dtpsy_1410	COG0640	Transcriptional regulator
Dtpsy_1412	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Dtpsy_1413	COG0642	Histidine kinase
Dtpsy_1414	COG0745	RESPONSE REGULATOR receiver
Dtpsy_1419	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Dtpsy_1420	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Dtpsy_1421	COG0583	DNA-binding transcription factor activity
Dtpsy_1435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Dtpsy_1437	COG0670	Belongs to the BI1 family
Dtpsy_1438	COG3193	protein, possibly involved in utilization of glycolate and propanediol
Dtpsy_1445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Dtpsy_1448	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Dtpsy_1449	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Dtpsy_1450	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Dtpsy_1451	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Dtpsy_1452	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Dtpsy_1453	COG0072	phenylalanine-tRNA ligase activity
Dtpsy_1453	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Dtpsy_1454	COG0776	regulation of translation
Dtpsy_1455	COG0789	Transcriptional regulator
Dtpsy_1456	COG0505	Belongs to the CarA family
Dtpsy_1458	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Dtpsy_1464	COG0642	Histidine kinase
Dtpsy_1465	COG0745	RESPONSE REGULATOR receiver
Dtpsy_1466	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Dtpsy_1467	COG0586	Pfam SNARE associated Golgi protein
Dtpsy_1469	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Dtpsy_1473	COG1534	Rna-binding protein
Dtpsy_1474	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Dtpsy_1475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Dtpsy_1477	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Dtpsy_1480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Dtpsy_1485	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Dtpsy_1486	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Dtpsy_1487	COG0573	inorganic phosphate transmembrane transporter activity
Dtpsy_1488	COG0581	inorganic phosphate transmembrane transporter activity
Dtpsy_1489	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Dtpsy_1490	COG0704	Plays a role in the regulation of phosphate uptake
Dtpsy_1491	COG0745	RESPONSE REGULATOR receiver
Dtpsy_1493	COG0534	Mate efflux family protein
Dtpsy_1495	COG0254	rRNA binding
Dtpsy_1496	COG0842	Transport permease protein
Dtpsy_1497	COG0842	Transport permease protein
Dtpsy_1497	COG1129	ABC transporter
Dtpsy_1498	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Dtpsy_1500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Dtpsy_1503	COG1074	ATP-dependent DNA helicase activity
Dtpsy_1504	COG2226	methyltransferase
Dtpsy_1505	COG0492	ferredoxin-NADP+ reductase activity
Dtpsy_1507	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Dtpsy_1508	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Dtpsy_1509	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Dtpsy_1512	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Dtpsy_1513	COG2011	ABC-type metal ion transport system permease component
Dtpsy_1515	COG1464	Belongs to the NlpA lipoprotein family
Dtpsy_1517	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Dtpsy_1519	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Dtpsy_1520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Dtpsy_1521	COG4208	sulfate ABC transporter
Dtpsy_1522	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Dtpsy_1523	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Dtpsy_1526	COG4773	Receptor
Dtpsy_1530	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Dtpsy_1530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Dtpsy_1531	COG2755	lipolytic protein G-D-S-L family
Dtpsy_1531	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Dtpsy_1532	COG2963	transposase activity
Dtpsy_1533	COG2801	Transposase and inactivated derivatives
Dtpsy_1534	COG3181	Tripartite tricarboxylate transporter family receptor
Dtpsy_1537	COG2814	Major facilitator Superfamily
Dtpsy_1538	COG1122	ATPase activity
Dtpsy_1540	COG1268	BioY protein
Dtpsy_1541	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_1542	COG0183	Belongs to the thiolase family
Dtpsy_1544	COG1408	metallophosphoesterase
Dtpsy_1546	COG1643	Atp-dependent helicase
Dtpsy_1549	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Dtpsy_1550	COG0252	asparaginase activity
Dtpsy_1551	COG0563	adenylate kinase activity
Dtpsy_1552	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Dtpsy_1553	COG2835	tetraacyldisaccharide 4'-kinase activity
Dtpsy_1554	COG1663	tetraacyldisaccharide 4'-kinase activity
Dtpsy_1555	COG0848	biopolymer transport protein
Dtpsy_1556	COG0811	peptide transport
Dtpsy_1557	COG1570	exodeoxyribonuclease VII activity
Dtpsy_1558	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Dtpsy_1570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Dtpsy_1574	COG0589	response to stress
Dtpsy_1577	COG0582	viral genome integration into host DNA
Dtpsy_1578	COG2832	Protein of unknown function (DUF454)
Dtpsy_1579	COG0242	peptide deformylase activity
Dtpsy_1581	COG0024	Methionine aminopeptidase
Dtpsy_1582	COG0047	phosphoribosylformylglycinamidine synthase activity
Dtpsy_1582	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Dtpsy_1584	COG2354	Protein conserved in bacteria
Dtpsy_1585	COG3047	cAMP biosynthetic process
Dtpsy_1586	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Dtpsy_1587	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Dtpsy_1589	COG0826	peptidase U32
Dtpsy_1590	COG0786	glutamate:sodium symporter activity
Dtpsy_1592	COG0590	tRNA wobble adenosine to inosine editing
Dtpsy_1593	COG1619	proteins homologs of microcin C7 resistance protein MccF
Dtpsy_1596	COG1741	Belongs to the pirin family
Dtpsy_1597	COG0455	bacterial-type flagellum organization
Dtpsy_1598	COG3706	GGDEF domain
Dtpsy_1601	COG0626	cystathionine gamma-synthase activity
Dtpsy_1604	COG4181	ATPase activity
Dtpsy_1605	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Dtpsy_1606	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Dtpsy_1610	COG5507	3-demethylubiquinone-9 3-methyltransferase
Dtpsy_1612	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Dtpsy_1613	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Dtpsy_1616	COG0179	Fumarylacetoacetate (FAA) hydrolase
Dtpsy_1620	COG0583	DNA-binding transcription factor activity
Dtpsy_1621	COG3550	peptidyl-serine autophosphorylation
Dtpsy_1623	COG0583	DNA-binding transcription factor activity
Dtpsy_1624	COG3048	D-serine ammonia-lyase activity
Dtpsy_1626	COG0154	amidase activity
Dtpsy_1630	COG1739	Uncharacterized protein family UPF0029
Dtpsy_1634	COG3384	dioxygenase
Dtpsy_1637	COG1959	2 iron, 2 sulfur cluster binding
Dtpsy_1638	COG1104	cysteine desulfurase activity
Dtpsy_1639	COG0822	iron-sulfur transferase activity
Dtpsy_1642	COG0443	Heat shock 70 kDa protein
Dtpsy_1643	COG0633	Ferredoxin
Dtpsy_1644	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Dtpsy_1646	COG0579	oxidoreductase
Dtpsy_1650	COG0167	dihydroorotate dehydrogenase activity
Dtpsy_1651	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Dtpsy_1654	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Dtpsy_1655	COG4566	intracellular signal transduction
Dtpsy_1658	COG0508	dehydrogenase complex catalyzes the overall conversion of
Dtpsy_1659	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Dtpsy_1661	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Dtpsy_1664	COG0791	NLP P60 protein
Dtpsy_1665	COG2814	Major facilitator Superfamily
Dtpsy_1666	COG1132	(ABC) transporter
Dtpsy_1668	COG1742	UPF0060 membrane protein
Dtpsy_1669	COG1196	nuclear chromosome segregation
Dtpsy_1672	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Dtpsy_1673	COG1752	Esterase of the alpha-beta hydrolase superfamily
Dtpsy_1674	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Dtpsy_1681	COG3243	poly(R)-hydroxyalkanoic acid synthase
Dtpsy_1682	COG0183	Belongs to the thiolase family
Dtpsy_1687	COG1136	(ABC) transporter
Dtpsy_1688	COG2951	lytic endotransglycosylase activity
Dtpsy_1689	COG2925	Exonuclease
Dtpsy_1691	COG3284	Transcriptional regulator
Dtpsy_1694	COG1012	belongs to the aldehyde dehydrogenase family
Dtpsy_1695	COG1283	sodium-dependent phosphate transmembrane transporter activity
Dtpsy_1696	COG0628	permease
Dtpsy_1697	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Dtpsy_1700	COG0217	transcriptional regulatory protein
Dtpsy_1701	COG0625	glutathione transferase activity
Dtpsy_1702	COG0433	COG0433 Predicted ATPase
Dtpsy_1703	COG0217	transcriptional regulatory protein
Dtpsy_1704	COG0151	Belongs to the GarS family
Dtpsy_1705	COG0408	coproporphyrinogen oxidase activity
Dtpsy_1706	COG0799	negative regulation of ribosome biogenesis
Dtpsy_1707	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Dtpsy_1708	COG0424	maF-like protein
Dtpsy_1715	COG3391	amine dehydrogenase activity
Dtpsy_1716	COG2010	Cytochrome c
Dtpsy_1718	COG1648	precorrin-2 dehydrogenase activity
Dtpsy_1718	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Dtpsy_1719	COG1530	ribonuclease E activity
Dtpsy_1720	COG0436	Aminotransferase
Dtpsy_1721	COG0583	DNA-binding transcription factor activity
Dtpsy_1725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Dtpsy_1729	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Dtpsy_1732	COG0589	response to stress
Dtpsy_1733	COG3181	Tripartite tricarboxylate transporter family receptor
Dtpsy_1734	COG0183	Belongs to the thiolase family
Dtpsy_1735	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_1738	COG0545	Peptidyl-prolyl cis-trans isomerase
Dtpsy_1739	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Dtpsy_1739	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Dtpsy_1741	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Dtpsy_1744	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Dtpsy_1749	COG4120	Belongs to the binding-protein-dependent transport system permease family
Dtpsy_1753	COG0642	Histidine kinase
Dtpsy_1754	COG0745	RESPONSE REGULATOR receiver
Dtpsy_1759	COG0753	catalase activity
Dtpsy_1760	COG1252	NADH dehydrogenase
Dtpsy_1764	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Dtpsy_1766	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Dtpsy_1767	COG0587	DNA-directed DNA polymerase activity
Dtpsy_1772	COG2197	response regulator
Dtpsy_1774	COG2982	Protein involved in outer membrane biogenesis
Dtpsy_1777	COG0564	pseudouridine synthase activity
Dtpsy_1778	COG1012	belongs to the aldehyde dehydrogenase family
Dtpsy_1779	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Dtpsy_1780	COG3706	GGDEF domain
Dtpsy_1781	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Dtpsy_1782	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Dtpsy_1783	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Dtpsy_1783	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Dtpsy_1784	COG0583	DNA-binding transcription factor activity
Dtpsy_1785	COG1741	Belongs to the pirin family
Dtpsy_1786	COG2259	Doxx family
Dtpsy_1787	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Dtpsy_1788	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Dtpsy_1790	COG4948	Mandelate Racemase Muconate Lactonizing
Dtpsy_1791	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Dtpsy_1793	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Dtpsy_1795	COG2186	Transcriptional regulator
Dtpsy_1796	COG4948	Mandelate Racemase Muconate Lactonizing
Dtpsy_1799	COG3171	Protein conserved in bacteria
Dtpsy_1800	COG0133	tryptophan synthase activity
Dtpsy_1811	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_1814	COG0583	DNA-binding transcription factor activity
Dtpsy_1817	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_1823	COG2133	pyrroloquinoline quinone binding
Dtpsy_1832	COG0045	succinate-CoA ligase (ADP-forming) activity
Dtpsy_1832	COG1042	CoA-binding domain protein
Dtpsy_1832	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Dtpsy_1834	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Dtpsy_1837	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Dtpsy_1838	COG1309	transcriptional regulator
Dtpsy_1839	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Dtpsy_1847	COG1022	Amp-dependent synthetase and ligase
Dtpsy_1848	COG1802	Transcriptional regulator
Dtpsy_1850	COG1703	isobutyryl-CoA mutase activity
Dtpsy_1851	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Dtpsy_1853	COG0439	Biotin carboxylase
Dtpsy_1855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Dtpsy_1863	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Dtpsy_1869	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_1870	COG0346	lactoylglutathione lyase activity
Dtpsy_1871	COG0800	Aldolase
Dtpsy_1873	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Dtpsy_1874	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Dtpsy_1875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Dtpsy_1876	COG3265	gluconokinase activity
Dtpsy_1877	COG1609	Transcriptional regulator
Dtpsy_1880	COG2032	superoxide dismutase activity
Dtpsy_1881	COG0259	pyridoxamine-phosphate oxidase activity
Dtpsy_1887	COG2878	Part of a membrane complex involved in electron transport
Dtpsy_1890	COG2171	N-acyltransferase activity
Dtpsy_1892	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Dtpsy_1893	COG2890	protein-(glutamine-N5) methyltransferase activity
Dtpsy_1895	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_1896	COG0542	response to heat
Dtpsy_1897	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Dtpsy_1900	COG1199	ATP-dependent helicase activity
Dtpsy_1901	COG0631	protein serine/threonine phosphatase activity
Dtpsy_1903	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Dtpsy_1904	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Dtpsy_1905	COG0508	dehydrogenase complex catalyzes the overall conversion of
Dtpsy_1906	COG0567	Dehydrogenase, E1 component
Dtpsy_1912	COG0589	response to stress
Dtpsy_1913	COG3622	Belongs to the hyi family
Dtpsy_1915	COG4172	Belongs to the ABC transporter superfamily
Dtpsy_1916	COG4239	(ABC) transporter, permease
Dtpsy_1917	COG4174	ABC transporter (Permease)
Dtpsy_1918	COG4166	transmembrane transport
Dtpsy_1921	COG0415	Belongs to the DNA photolyase family
Dtpsy_1922	COG0625	glutathione transferase activity
Dtpsy_1923	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Dtpsy_1924	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Dtpsy_1925	COG2860	membrane
Dtpsy_1926	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Dtpsy_1926	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Dtpsy_1929	COG0175	sulfate reduction
Dtpsy_1930	COG0175	sulfate reduction
Dtpsy_1931	COG2895	sulfate adenylyltransferase (ATP) activity
Dtpsy_1932	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Dtpsy_1933	COG0492	ferredoxin-NADP+ reductase activity
Dtpsy_1935	COG0351	phosphomethylpyrimidine kinase
Dtpsy_1938	COG2022	thiamine diphosphate biosynthetic process
Dtpsy_1941	COG1250	3-hydroxyacyl-CoA dehydrogenase
Dtpsy_1942	COG1024	Enoyl-CoA hydratase
Dtpsy_1946	COG1414	Transcriptional regulator
Dtpsy_1948	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Dtpsy_1950	COG1183	phosphatidylcholine synthase activity
Dtpsy_1951	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Dtpsy_1952	COG0440	acetolactate synthase activity
Dtpsy_1953	COG0028	Belongs to the TPP enzyme family
Dtpsy_1954	COG1595	DNA-templated transcription, initiation
Dtpsy_1960	COG0347	Belongs to the P(II) protein family
Dtpsy_1961	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Dtpsy_1961	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Dtpsy_1963	COG0835	chemotaxis
Dtpsy_1964	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Dtpsy_1969	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Dtpsy_1970	COG0746	molybdenum cofactor guanylyltransferase activity
Dtpsy_1973	COG0328	RNA-DNA hybrid ribonuclease activity
Dtpsy_1974	COG2226	methyltransferase
Dtpsy_1975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Dtpsy_1976	COG1388	LysM domain
Dtpsy_1976	COG0741	lytic transglycosylase activity
Dtpsy_1979	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Dtpsy_1981	COG0823	Involved in the tonB-independent uptake of proteins
Dtpsy_1982	COG1132	(ABC) transporter
Dtpsy_1984	COG0084	hydrolase, TatD family'
Dtpsy_1986	COG0470	DNA polymerase III
Dtpsy_1987	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Dtpsy_1988	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Dtpsy_1989	COG0354	folic acid binding
Dtpsy_1990	COG2153	protein acetylation
Dtpsy_1997	COG2183	response to ionizing radiation
Dtpsy_2000	COG2814	Major facilitator Superfamily
Dtpsy_2001	COG2814	Major facilitator Superfamily
Dtpsy_2005	COG2153	protein acetylation
Dtpsy_2006	COG2130	NADP-dependent
Dtpsy_2012	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Dtpsy_2013	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Dtpsy_2014	COG3639	organic phosphonate transmembrane transporter activity
Dtpsy_2017	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_2018	COG3706	GGDEF domain
Dtpsy_2018	COG0745	RESPONSE REGULATOR receiver
Dtpsy_2019	COG0183	Belongs to the thiolase family
Dtpsy_2020	COG1250	3-hydroxyacyl-CoA dehydrogenase
Dtpsy_2020	COG1024	Enoyl-CoA hydratase
Dtpsy_2022	COG0411	ABC transporter
Dtpsy_2024	COG0559	Belongs to the binding-protein-dependent transport system permease family
Dtpsy_2026	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_2027	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Dtpsy_2028	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Dtpsy_2029	COG2917	probably involved in intracellular septation
Dtpsy_2031	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Dtpsy_2034	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Dtpsy_2036	COG0688	phosphatidylethanolamine metabolic process
Dtpsy_2043	COG0741	lytic transglycosylase activity
Dtpsy_2044	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Dtpsy_2045	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Dtpsy_2046	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Dtpsy_2049	COG2267	carboxylic ester hydrolase activity
Dtpsy_2052	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Dtpsy_2053	COG1067	ATP-dependent peptidase activity
Dtpsy_2063	COG0410	ABC transporter
Dtpsy_2064	COG0411	ABC transporter
Dtpsy_2067	COG2204	response regulator
Dtpsy_2072	COG3181	Tripartite tricarboxylate transporter family receptor
Dtpsy_2074	COG0642	Histidine kinase
Dtpsy_2075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Dtpsy_2077	COG3800	Transcriptional regulator
Dtpsy_2077	COG1396	sequence-specific DNA binding
Dtpsy_2083	COG0583	DNA-binding transcription factor activity
Dtpsy_2084	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Dtpsy_2086	COG0527	aspartate kinase activity
Dtpsy_2087	COG0037	tRNA processing
Dtpsy_2091	COG0215	cysteine-tRNA ligase activity
Dtpsy_2095	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Dtpsy_2096	COG3228	Belongs to the MtfA family
Dtpsy_2098	COG1522	sequence-specific DNA binding
Dtpsy_2101	COG3384	dioxygenase
Dtpsy_2104	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Dtpsy_2106	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Dtpsy_2107	COG1840	ABC-type Fe3 transport system, periplasmic component
Dtpsy_2121	COG3328	transposase activity
Dtpsy_2136	COG2826	transposase and inactivated derivatives, IS30 family
Dtpsy_2137	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Dtpsy_2138	COG0517	IMP dehydrogenase activity
Dtpsy_2138	COG0516	GMP reductase activity
Dtpsy_2141	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Dtpsy_2145	COG1929	Belongs to the glycerate kinase type-1 family
Dtpsy_2146	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Dtpsy_2149	COG0789	Transcriptional regulator
Dtpsy_2151	COG0672	)-iron permease
Dtpsy_2157	COG3041	Addiction module toxin RelE StbE family
Dtpsy_2158	COG3077	Addiction module antitoxin, RelB DinJ family
Dtpsy_2168	COG2801	Transposase and inactivated derivatives
Dtpsy_2183	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Dtpsy_2187	COG3174	membrane
Dtpsy_2202	COG5002	protein histidine kinase activity
Dtpsy_2204	COG0640	Transcriptional regulator
Dtpsy_2205	COG2226	methyltransferase
Dtpsy_2213	COG2194	sulfuric ester hydrolase activity
Dtpsy_2219	COG2963	transposase activity
Dtpsy_2220	COG2801	Transposase and inactivated derivatives
Dtpsy_2224	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Dtpsy_2227	COG1286	toxin biosynthetic process
Dtpsy_2229	COG0285	dihydrofolate synthase activity
Dtpsy_2230	COG1393	Belongs to the ArsC family
Dtpsy_2232	COG3123	guanosine phosphorylase activity
Dtpsy_2233	COG0137	argininosuccinate synthase activity
Dtpsy_2234	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Dtpsy_2235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Dtpsy_2236	COG1595	DNA-templated transcription, initiation
Dtpsy_2237	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Dtpsy_2238	COG0471	metal ion transport
Dtpsy_2240	COG1666	GTP binding
Dtpsy_2241	COG3577	Aspartyl protease
Dtpsy_2243	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Dtpsy_2245	COG0667	Aldo Keto reductase
Dtpsy_2249	COG0308	aminopeptidase N
Dtpsy_2250	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Dtpsy_2251	COG1793	dna ligase
Dtpsy_2252	COG1982	Orn Lys Arg decarboxylase major
Dtpsy_2257	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Dtpsy_2258	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Dtpsy_2259	COG0436	Aminotransferase
Dtpsy_2260	COG0824	Thioesterase
Dtpsy_2264	COG0477	Major facilitator Superfamily
Dtpsy_2266	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Dtpsy_2267	COG1845	cytochrome c oxidase, subunit III
Dtpsy_2268	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Dtpsy_2271	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Dtpsy_2280	COG4106	trans-aconitate 2-methyltransferase activity
Dtpsy_2281	COG0039	L-malate dehydrogenase activity
Dtpsy_2282	COG2188	Transcriptional regulator
Dtpsy_2283	COG2009	succinate dehydrogenase
Dtpsy_2285	COG1053	succinate dehydrogenase
Dtpsy_2286	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Dtpsy_2287	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Dtpsy_2288	COG0372	Belongs to the citrate synthase family
Dtpsy_2290	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Dtpsy_2291	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Dtpsy_2294	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Dtpsy_2297	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_2300	COG3264	Mechanosensitive ion channel
Dtpsy_2300	COG1511	domain protein
Dtpsy_2301	COG1024	Enoyl-CoA hydratase
Dtpsy_2302	COG0123	including yeast histone deacetylase and acetoin utilization protein
Dtpsy_2303	COG0714	Associated with various cellular activities
Dtpsy_2306	COG2951	lytic endotransglycosylase activity
Dtpsy_2307	COG0583	DNA-binding transcription factor activity
Dtpsy_2309	COG0683	leucine binding
Dtpsy_2312	COG0577	efflux transmembrane transporter activity
Dtpsy_2312	COG1136	(ABC) transporter
Dtpsy_2313	COG0577	efflux transmembrane transporter activity
Dtpsy_2313	COG1136	(ABC) transporter
Dtpsy_2314	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Dtpsy_2315	COG1538	Outer membrane efflux protein
Dtpsy_2317	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Dtpsy_2320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Dtpsy_2321	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Dtpsy_2322	COG1116	anion transmembrane transporter activity
Dtpsy_2323	COG0517	IMP dehydrogenase activity
Dtpsy_2323	COG0516	GMP reductase activity
Dtpsy_2326	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Dtpsy_2328	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Dtpsy_2329	COG2146	nitrite reductase [NAD(P)H] activity
Dtpsy_2330	COG0243	molybdopterin cofactor binding
Dtpsy_2331	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Dtpsy_2333	COG1607	acyl-coa hydrolase
Dtpsy_2335	COG2081	HI0933 family
Dtpsy_2339	COG0822	iron-sulfur transferase activity
Dtpsy_2340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Dtpsy_2342	COG0396	ATPase activity
Dtpsy_2343	COG0719	Fe-S assembly protein
Dtpsy_2344	COG0640	Transcriptional regulator
Dtpsy_2347	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Dtpsy_2348	COG1610	YqeY-like protein
Dtpsy_2349	COG0473	3-isopropylmalate dehydrogenase activity
Dtpsy_2351	COG1230	cation diffusion facilitator family transporter
Dtpsy_2354	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Dtpsy_2355	COG1451	nucleotide metabolic process
Dtpsy_2358	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Dtpsy_2359	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Dtpsy_2360	COG0583	DNA-binding transcription factor activity
Dtpsy_2362	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Dtpsy_2364	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Dtpsy_2367	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Dtpsy_2369	COG0450	alkyl hydroperoxide reductase
Dtpsy_2375	COG1289	transmembrane transporter activity
Dtpsy_2376	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Dtpsy_2377	COG0181	hydroxymethylbilane synthase activity
Dtpsy_2384	COG0425	Belongs to the sulfur carrier protein TusA family
Dtpsy_2385	COG2816	NAD+ diphosphatase activity
Dtpsy_2388	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Dtpsy_2389	COG0724	RNA recognition motif
Dtpsy_2391	COG0300	oxidoreductase activity
Dtpsy_2395	COG0840	transmembrane signaling receptor activity
Dtpsy_2396	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Dtpsy_2398	COG1231	oxidoreductase activity
Dtpsy_2400	COG3040	lipid binding
Dtpsy_2405	COG1346	cytolysis
Dtpsy_2406	COG0583	DNA-binding transcription factor activity
Dtpsy_2407	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_2408	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Dtpsy_2418	COG0617	tRNA 3'-terminal CCA addition
Dtpsy_2420	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Dtpsy_2421	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Dtpsy_2423	COG0589	response to stress
Dtpsy_2426	COG0728	peptidoglycan biosynthetic process
Dtpsy_2427	COG0268	Binds directly to 16S ribosomal RNA
Dtpsy_2429	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Dtpsy_2430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Dtpsy_2437	COG1522	sequence-specific DNA binding
Dtpsy_2438	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Dtpsy_2440	COG3483	tryptophan 2,3-dioxygenase activity
Dtpsy_2441	COG2366	antibiotic biosynthetic process
Dtpsy_2442	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Dtpsy_2447	COG1129	ABC transporter
Dtpsy_2449	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Dtpsy_2450	COG5002	protein histidine kinase activity
Dtpsy_2450	COG3447	MASE1 domain protein
Dtpsy_2450	COG5001	Diguanylate cyclase
Dtpsy_2452	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Dtpsy_2453	COG3300	MHYT domain
Dtpsy_2453	COG5001	Diguanylate cyclase
Dtpsy_2454	COG0537	adenosine 5'-monophosphoramidase activity
Dtpsy_2455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Dtpsy_2456	COG2814	Major facilitator Superfamily
Dtpsy_2457	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Dtpsy_2458	COG1136	(ABC) transporter
Dtpsy_2459	COG0071	Belongs to the small heat shock protein (HSP20) family
Dtpsy_2464	COG0559	Belongs to the binding-protein-dependent transport system permease family
Dtpsy_2472	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Dtpsy_2475	COG1122	ATPase activity
Dtpsy_2480	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Dtpsy_2482	COG2814	Major facilitator Superfamily
Dtpsy_2483	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_2485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Dtpsy_2486	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Dtpsy_2490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Dtpsy_2491	COG0583	DNA-binding transcription factor activity
Dtpsy_2494	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Dtpsy_2495	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Dtpsy_2496	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Dtpsy_2498	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_2500	COG0745	RESPONSE REGULATOR receiver
Dtpsy_2501	COG2205	protein histidine kinase activity
Dtpsy_2502	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Dtpsy_2502	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Dtpsy_2503	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Dtpsy_2503	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Dtpsy_2504	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Dtpsy_2506	COG0560	Phosphoserine phosphatase
Dtpsy_2509	COG0583	DNA-binding transcription factor activity
Dtpsy_2510	COG1959	2 iron, 2 sulfur cluster binding
Dtpsy_2514	COG0667	Aldo Keto reductase
Dtpsy_2515	COG2900	Belongs to the SlyX family
Dtpsy_2516	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Dtpsy_2517	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Dtpsy_2523	COG4372	Transposase
Dtpsy_2524	COG1215	transferase activity, transferring glycosyl groups
Dtpsy_2526	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Dtpsy_2527	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Dtpsy_2528	COG0778	Nitroreductase
Dtpsy_2529	COG1492	cobalamin metabolic process
Dtpsy_2533	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Dtpsy_2541	COG4636	protein conserved in cyanobacteria
Dtpsy_2542	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Dtpsy_2542	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Dtpsy_2543	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Dtpsy_2550	COG0542	response to heat
Dtpsy_2551	COG0314	molybdopterin synthase activity
Dtpsy_2556	COG0303	'Molybdopterin
Dtpsy_2557	COG1763	Mo-molybdopterin cofactor biosynthetic process
Dtpsy_2560	COG0436	Aminotransferase
Dtpsy_2562	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Dtpsy_2563	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Dtpsy_2565	COG0305	Participates in initiation and elongation during chromosome replication
Dtpsy_2566	COG0359	binds to the 23S rRNA
Dtpsy_2567	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Dtpsy_2568	COG2965	DNA replication, synthesis of RNA primer
Dtpsy_2569	COG0360	Binds together with S18 to 16S ribosomal RNA
Dtpsy_2570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Dtpsy_2571	COG0443	Heat shock 70 kDa protein
Dtpsy_2572	COG0484	heat shock protein binding
Dtpsy_2578	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Dtpsy_2580	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Dtpsy_2582	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Dtpsy_2585	COG0066	3-isopropylmalate dehydratase activity
Dtpsy_2586	COG0473	3-isopropylmalate dehydrogenase activity
Dtpsy_2588	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Dtpsy_2590	COG0101	tRNA pseudouridine synthase activity
Dtpsy_2591	COG0135	phosphoribosylanthranilate isomerase activity
Dtpsy_2592	COG0133	tryptophan synthase activity
Dtpsy_2593	COG0159	tryptophan synthase activity
Dtpsy_2594	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Dtpsy_2595	COG0762	integral membrane protein
Dtpsy_2597	COG0438	transferase activity, transferring glycosyl groups
Dtpsy_2598	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Dtpsy_2603	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Dtpsy_2604	COG0745	RESPONSE REGULATOR receiver
Dtpsy_2607	COG0559	Belongs to the binding-protein-dependent transport system permease family
Dtpsy_2612	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Dtpsy_2614	COG1472	Belongs to the glycosyl hydrolase 3 family
Dtpsy_2615	COG0736	holo-[acyl-carrier-protein] synthase activity
Dtpsy_2616	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Dtpsy_2617	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
Dtpsy_2618	COG1381	Involved in DNA repair and RecF pathway recombination
Dtpsy_2619	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Dtpsy_2620	COG0571	ribonuclease III activity
Dtpsy_2622	COG0681	Belongs to the peptidase S26 family
Dtpsy_2623	COG0481	GTPase activity
Dtpsy_2624	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Dtpsy_2629	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Dtpsy_2630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Dtpsy_2631	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_2632	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Dtpsy_2633	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Dtpsy_2634	COG0416	fatty acid biosynthetic process
Dtpsy_2635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Dtpsy_2636	COG1399	metal-binding, possibly nucleic acid-binding protein
Dtpsy_2637	COG0424	maF-like protein
Dtpsy_2639	COG0616	signal peptide processing
Dtpsy_2639	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Dtpsy_2642	COG0564	pseudouridine synthase activity
Dtpsy_2643	COG1530	ribonuclease E activity
Dtpsy_2644	COG3022	response to hydroperoxide
Dtpsy_2647	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Dtpsy_2647	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Dtpsy_2648	COG0840	transmembrane signaling receptor activity
Dtpsy_2649	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Dtpsy_2651	COG1304	FMN binding
Dtpsy_2657	COG0395	ABC-type sugar transport system, permease component
Dtpsy_2658	COG1175	transmembrane transport
Dtpsy_2660	COG3842	ATPase activity
Dtpsy_2662	COG0753	catalase activity
Dtpsy_2664	COG0165	Argininosuccinate lyase
Dtpsy_2665	COG3275	phosphorelay sensor kinase activity
Dtpsy_2668	COG0412	Dienelactone hydrolase
Dtpsy_2672	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Dtpsy_2675	COG2885	chlorophyll binding
Dtpsy_2677	COG0210	DNA helicase
Dtpsy_2679	COG0516	GMP reductase activity
Dtpsy_2681	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Dtpsy_2685	COG1429	ligase activity, forming nitrogen-metal bonds
Dtpsy_2686	COG4771	TonB-dependent receptor
Dtpsy_2692	COG2814	Major facilitator Superfamily
Dtpsy_2693	COG0513	Belongs to the DEAD box helicase family
Dtpsy_2694	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Dtpsy_2695	COG0501	Belongs to the peptidase M48B family
Dtpsy_2696	COG2154	pterin-4-alpha-carbinolamine dehydratase
Dtpsy_2697	COG1162	GTPase activity
Dtpsy_2698	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Dtpsy_2699	COG0494	nUDIX hydrolase
Dtpsy_2700	COG0335	large ribosomal subunit rRNA binding
Dtpsy_2701	COG0336	Belongs to the RNA methyltransferase TrmD family
Dtpsy_2702	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Dtpsy_2703	COG0228	four-way junction DNA binding
Dtpsy_2706	COG0306	phosphate transporter
Dtpsy_2707	COG1392	Phosphate transport regulator
Dtpsy_2710	COG0411	ABC transporter
Dtpsy_2712	COG0559	Belongs to the binding-protein-dependent transport system permease family
Dtpsy_2713	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Dtpsy_2718	COG1573	uracil-dna glycosylase
Dtpsy_2719	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Dtpsy_2720	COG1674	ftsk spoiiie
Dtpsy_2721	COG0492	ferredoxin-NADP+ reductase activity
Dtpsy_2722	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Dtpsy_2723	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Dtpsy_2725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Dtpsy_2725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Dtpsy_2729	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Dtpsy_2730	COG3132	Protein of unknown function, DUF480
Dtpsy_2731	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_2732	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_2734	COG0196	riboflavin kinase activity
Dtpsy_2736	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Dtpsy_2737	COG1283	sodium-dependent phosphate transmembrane transporter activity
Dtpsy_2741	COG0697	spore germination
Dtpsy_2744	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_2747	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Dtpsy_2748	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Dtpsy_2750	COG0084	hydrolase, TatD family'
Dtpsy_2752	COG0640	Transcriptional regulator
Dtpsy_2754	COG1136	(ABC) transporter
Dtpsy_2755	COG4591	ABC-type transport system involved in lipoprotein release permease component
Dtpsy_2756	COG0584	glycerophosphoryl diester phosphodiesterase
Dtpsy_2758	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Dtpsy_2762	COG0840	transmembrane signaling receptor activity
Dtpsy_2763	COG0613	PHP domain protein
Dtpsy_2764	COG0009	L-threonylcarbamoyladenylate synthase
Dtpsy_2766	COG0714	Associated with various cellular activities
Dtpsy_2767	COG3256	nitric oxide reductase
Dtpsy_2768	COG2010	Cytochrome c
Dtpsy_2770	COG1994	Peptidase M50
Dtpsy_2771	COG0180	Tryptophanyl-tRNA synthetase
Dtpsy_2772	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Dtpsy_2774	COG1253	flavin adenine dinucleotide binding
Dtpsy_2775	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Dtpsy_2776	COG1047	Peptidyl-prolyl cis-trans
Dtpsy_2777	COG2003	Belongs to the UPF0758 family
Dtpsy_2779	COG1193	negative regulation of DNA recombination
Dtpsy_2785	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Dtpsy_2786	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Dtpsy_2790	COG0437	4 iron, 4 sulfur cluster binding
Dtpsy_2791	COG3383	formate dehydrogenase (NAD+) activity
Dtpsy_2791	COG0243	molybdopterin cofactor binding
Dtpsy_2797	COG3383	formate dehydrogenase (NAD+) activity
Dtpsy_2800	COG0489	protein tyrosine kinase activity
Dtpsy_2803	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Dtpsy_2806	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Dtpsy_2806	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Dtpsy_2810	COG1304	FMN binding
Dtpsy_2811	COG0028	Belongs to the TPP enzyme family
Dtpsy_2816	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Dtpsy_2817	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Dtpsy_2820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Dtpsy_2822	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Dtpsy_2823	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Dtpsy_2824	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Dtpsy_2825	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Dtpsy_2827	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Dtpsy_2828	COG0588	phosphoglycerate mutase activity
Dtpsy_2829	COG0793	Belongs to the peptidase S41A family
Dtpsy_2830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Dtpsy_2832	COG2197	response regulator
Dtpsy_2834	COG5487	UPF0391 membrane protein
Dtpsy_2839	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Dtpsy_2840	COG0742	ribosomal rna small subunit methyltransferase
Dtpsy_2841	COG0612	Peptidase, M16
Dtpsy_2842	COG0612	Peptidase, M16
Dtpsy_2845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Dtpsy_2846	COG3181	Tripartite tricarboxylate transporter family receptor
Dtpsy_2849	COG1999	signal sequence binding
Dtpsy_2850	COG0109	protoheme IX farnesyltransferase activity
Dtpsy_2857	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Dtpsy_2859	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Dtpsy_2862	COG2226	methyltransferase
Dtpsy_2863	COG1040	competence protein
Dtpsy_2864	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Dtpsy_2866	COG1192	Involved in chromosome partitioning
Dtpsy_2867	COG1280	lysine exporter protein (LysE YggA)
Dtpsy_2868	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Dtpsy_2868	COG0475	glutathione-regulated potassium exporter activity
Dtpsy_2870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Dtpsy_2871	COG0183	Belongs to the thiolase family
Dtpsy_2872	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Dtpsy_2874	COG1414	Transcriptional regulator
Dtpsy_2888	COG1178	ABC-type Fe3 transport system permease component
Dtpsy_2889	COG3842	ATPase activity
Dtpsy_2893	COG0540	Belongs to the ATCase OTCase family
Dtpsy_2894	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Dtpsy_2895	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Dtpsy_2896	COG1678	Uncharacterized ACR, COG1678
Dtpsy_2897	COG0643	Histidine kinase
Dtpsy_2897	COG2198	Histidine kinase
Dtpsy_2898	COG0840	transmembrane signaling receptor activity
Dtpsy_2902	COG1773	rubredoxin
Dtpsy_2904	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Dtpsy_2906	COG4654	Cytochrome c, class I
Dtpsy_2907	COG0138	bifunctional purine biosynthesis protein purh
Dtpsy_2908	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
Dtpsy_2909	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Dtpsy_2910	COG1238	metal cluster binding
Dtpsy_2912	COG3181	Tripartite tricarboxylate transporter family receptor
Dtpsy_2913	COG1473	amidohydrolase
Dtpsy_2914	COG3639	organic phosphonate transmembrane transporter activity
Dtpsy_2915	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Dtpsy_2916	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Dtpsy_2917	COG3454	Phosphonate metabolism
Dtpsy_2918	COG4778	phosphonate C-P lyase system protein PhnL
Dtpsy_2919	COG4107	phosphonate C-P lyase system protein PhnK
Dtpsy_2921	COG3627	carbon phosphorus lyase activity
Dtpsy_2922	COG3626	phosphonate metabolism
Dtpsy_2925	COG2188	Transcriptional regulator
Dtpsy_2926	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Dtpsy_2928	COG0012	GTP binding
Dtpsy_2929	COG0633	Ferredoxin
Dtpsy_2929	COG3217	Mosc domain protein beta barrel domain protein
Dtpsy_2930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Dtpsy_2931	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Dtpsy_2933	COG1024	Enoyl-CoA hydratase
Dtpsy_2935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Dtpsy_2936	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Dtpsy_2937	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Dtpsy_2942	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Dtpsy_2942	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Dtpsy_2943	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Dtpsy_2947	COG2264	protein methyltransferase activity
Dtpsy_2948	COG0439	Biotin carboxylase
Dtpsy_2949	COG0511	ligase activity, forming carbon-carbon bonds
Dtpsy_2950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Dtpsy_2952	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Dtpsy_2954	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Dtpsy_2956	COG0312	modulator of DNA gyrase
Dtpsy_2957	COG0772	Belongs to the SEDS family
Dtpsy_2959	COG3150	esterase
Dtpsy_2961	COG3474	cytochrome
Dtpsy_2964	COG0557	exoribonuclease II activity
Dtpsy_2966	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Dtpsy_2967	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Dtpsy_2968	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Dtpsy_2969	COG0840	transmembrane signaling receptor activity
Dtpsy_2970	COG0840	transmembrane signaling receptor activity
Dtpsy_2971	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Dtpsy_2973	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Dtpsy_2974	COG0840	transmembrane signaling receptor activity
Dtpsy_2977	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Dtpsy_2978	COG1181	Belongs to the D-alanine--D-alanine ligase family
Dtpsy_2979	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Dtpsy_2980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Dtpsy_2981	COG0772	Belongs to the SEDS family
Dtpsy_2982	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Dtpsy_2983	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Dtpsy_2984	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Dtpsy_2985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Dtpsy_2987	COG3116	cell division
Dtpsy_2988	COG0275	rRNA processing
Dtpsy_2989	COG2001	Belongs to the MraZ family
Dtpsy_2990	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Dtpsy_2991	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Dtpsy_2993	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Dtpsy_2994	COG0523	cobalamin synthesis protein
Dtpsy_2996	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Dtpsy_2998	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Dtpsy_3001	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Dtpsy_3004	COG0501	Belongs to the peptidase M48B family
Dtpsy_3007	COG3568	Endonuclease Exonuclease Phosphatase
Dtpsy_3008	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Dtpsy_3010	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Dtpsy_3015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Dtpsy_3016	COG1024	Enoyl-CoA hydratase
Dtpsy_3017	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_3018	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_3019	COG0183	Belongs to the thiolase family
Dtpsy_3020	COG1250	3-hydroxyacyl-CoA dehydrogenase
Dtpsy_3020	COG1024	Enoyl-CoA hydratase
Dtpsy_3021	COG0583	DNA-binding transcription factor activity
Dtpsy_3023	COG0501	Belongs to the peptidase M48B family
Dtpsy_3026	COG0418	dihydroorotase activity
Dtpsy_3028	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Dtpsy_3029	COG0683	leucine binding
Dtpsy_3030	COG0683	leucine binding
Dtpsy_3033	COG0477	Major facilitator Superfamily
Dtpsy_3037	COG3706	GGDEF domain
Dtpsy_3037	COG0745	RESPONSE REGULATOR receiver
Dtpsy_3039	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Dtpsy_3042	COG1024	Enoyl-CoA hydratase
Dtpsy_3043	COG2318	DinB family
Dtpsy_3044	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Dtpsy_3045	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_3047	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Dtpsy_3048	COG5001	Diguanylate cyclase
Dtpsy_3048	COG2203	Gaf domain
Dtpsy_3048	COG3706	GGDEF domain
Dtpsy_3048	COG4251	negative regulation of phosphorylation
Dtpsy_3049	COG0747	negative chemotaxis
Dtpsy_3050	COG3012	SEC-C Motif Domain Protein
Dtpsy_3052	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_3053	COG0300	oxidoreductase activity
Dtpsy_3054	COG0183	Belongs to the thiolase family
Dtpsy_3055	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
Dtpsy_3056	COG0288	reversible hydration of carbon dioxide
Dtpsy_3057	COG1960	acyl-CoA dehydrogenase activity
Dtpsy_3058	COG0789	Transcriptional regulator
Dtpsy_3060	COG2201	protein-glutamate methylesterase activity
Dtpsy_3061	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Dtpsy_3063	COG0835	chemotaxis
Dtpsy_3064	COG0643	Histidine kinase
Dtpsy_3064	COG2198	Histidine kinase
Dtpsy_3065	COG2201	protein-glutamate methylesterase activity
Dtpsy_3068	COG2197	response regulator
Dtpsy_3070	COG1987	bacterial-type flagellum assembly
Dtpsy_3073	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Dtpsy_3081	COG1766	The M ring may be actively involved in energy transduction
Dtpsy_3082	COG1677	Flagellar hook-basal body complex protein FliE
Dtpsy_3090	COG0745	RESPONSE REGULATOR receiver
Dtpsy_3091	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Dtpsy_3093	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Dtpsy_3096	COG1191	sigma factor activity
Dtpsy_3100	COG1815	bacterial-type flagellum-dependent cell motility
Dtpsy_3101	COG1558	bacterial-type flagellum-dependent cell motility
Dtpsy_3102	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Dtpsy_3103	COG1749	Flagellar hook protein flgE
Dtpsy_3105	COG4786	Flagellar basal body rod
Dtpsy_3108	COG1706	bacterial-type flagellum-dependent cell motility
Dtpsy_3109	COG3951	Flagellar rod assembly protein muramidase FlgJ
Dtpsy_3109	COG1705	Flagellar rod assembly protein muramidase FlgJ
Dtpsy_3111	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Dtpsy_3113	COG0733	neurotransmitter:sodium symporter activity
Dtpsy_3114	COG2070	2-Nitropropane dioxygenase
Dtpsy_3115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Dtpsy_3117	COG0697	spore germination
Dtpsy_3118	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Dtpsy_3119	COG0384	phenazine biosynthesis protein PhzF
Dtpsy_3120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Dtpsy_3126	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Dtpsy_3127	COG4232	protein-disulfide reductase activity
Dtpsy_3129	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Dtpsy_3130	COG1832	CoA-binding protein
Dtpsy_3132	COG0861	Integral membrane protein TerC family
Dtpsy_3133	COG0583	DNA-binding transcription factor activity
Dtpsy_3134	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Dtpsy_3135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Dtpsy_3137	COG0679	Auxin Efflux Carrier
Dtpsy_3138	COG0210	DNA helicase
Dtpsy_3142	COG0589	response to stress
Dtpsy_3143	COG0343	queuine tRNA-ribosyltransferase activity
Dtpsy_3149	COG1522	sequence-specific DNA binding
Dtpsy_3150	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Dtpsy_3151	COG0204	Acyl-transferase
Dtpsy_3151	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_3156	COG3181	Tripartite tricarboxylate transporter family receptor
Dtpsy_3157	COG2072	flavoprotein involved in K transport
Dtpsy_3159	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Dtpsy_3163	COG2365	Tyrosine phosphatase family
Dtpsy_3164	COG0582	viral genome integration into host DNA
Dtpsy_3165	COG3328	transposase activity
Dtpsy_3179	COG2801	Transposase and inactivated derivatives
Dtpsy_3180	COG2963	transposase activity
Dtpsy_3182	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Dtpsy_3183	COG2255	four-way junction helicase activity
Dtpsy_3206	COG0616	signal peptide processing
Dtpsy_3216	COG1475	DNA binding
Dtpsy_3232	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Dtpsy_3236	COG1396	sequence-specific DNA binding
Dtpsy_3240	COG2204	response regulator
Dtpsy_3241	COG5000	phosphorelay sensor kinase activity
Dtpsy_3243	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Dtpsy_3243	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Dtpsy_3245	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Dtpsy_3246	COG0085	RNA polymerase activity
Dtpsy_3247	COG0222	ribosome binding
Dtpsy_3248	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Dtpsy_3249	COG0081	regulation of translation
Dtpsy_3250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Dtpsy_3252	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Dtpsy_3253	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Dtpsy_3256	COG0189	ligase activity
Dtpsy_3257	COG3135	benzoate transporter
Dtpsy_3258	COG3158	transport of potassium into the cell
Dtpsy_3260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Dtpsy_3261	COG0569	domain protein
Dtpsy_3262	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Dtpsy_3266	COG0495	leucyl-tRNA aminoacylation
Dtpsy_3267	COG0668	transmembrane transport
Dtpsy_3271	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Dtpsy_3272	COG0735	belongs to the Fur family
Dtpsy_3273	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Dtpsy_3275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Dtpsy_3276	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Dtpsy_3279	COG3118	belongs to the thioredoxin family
Dtpsy_3280	COG0693	protein deglycase activity
Dtpsy_3283	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Dtpsy_3284	COG0009	L-threonylcarbamoyladenylate synthase
Dtpsy_3288	COG2027	D-alanyl-D-alanine carboxypeptidase
Dtpsy_3292	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Dtpsy_3293	COG2414	aldehyde ferredoxin oxidoreductase
Dtpsy_3297	COG0598	Magnesium transport protein CorA
Dtpsy_3298	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Dtpsy_3299	COG0318	PFAM AMP-dependent synthetase and ligase
Dtpsy_3300	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Dtpsy_3301	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Dtpsy_3303	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Dtpsy_3305	COG0469	pyruvate kinase activity
Dtpsy_3306	COG0006	proline dipeptidase activity
Dtpsy_3309	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Dtpsy_3310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Dtpsy_3313	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Dtpsy_3314	COG1047	Peptidyl-prolyl cis-trans
Dtpsy_3318	COG1028	Short-chain dehydrogenase reductase Sdr
Dtpsy_3326	COG0625	glutathione transferase activity
Dtpsy_3327	COG2801	Transposase and inactivated derivatives
Dtpsy_3329	COG0625	glutathione transferase activity
Dtpsy_3336	COG3328	transposase activity
Dtpsy_3346	COG3181	Tripartite tricarboxylate transporter family receptor
Dtpsy_3347	COG0583	DNA-binding transcription factor activity
Dtpsy_3348	COG0642	Histidine kinase
Dtpsy_3351	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Dtpsy_3352	COG2137	regulation of response to DNA damage stimulus
Dtpsy_3354	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Dtpsy_3355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Dtpsy_3356	COG1862	Preprotein translocase
Dtpsy_3357	COG0668	transmembrane transport
Dtpsy_3359	COG1522	sequence-specific DNA binding
Dtpsy_3362	COG2814	Major facilitator Superfamily
Dtpsy_3363	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Dtpsy_3365	COG4566	intracellular signal transduction
Dtpsy_3367	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Dtpsy_3369	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Dtpsy_3372	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Dtpsy_3375	COG0625	glutathione transferase activity
Dtpsy_3377	COG4681	YaeQ
Dtpsy_3380	COG0861	Integral membrane protein TerC family
Dtpsy_3382	COG1950	PFAM Membrane protein of
Dtpsy_3383	COG4783	chaperone-mediated protein folding
Dtpsy_3384	COG0315	cyclic pyranopterin monophosphate synthase activity
Dtpsy_3385	COG4969	Belongs to the N-Me-Phe pilin family
Dtpsy_3387	COG4969	Belongs to the N-Me-Phe pilin family
Dtpsy_3388	COG1716	ATPase activity
Dtpsy_3390	COG0861	Integral membrane protein TerC family
Dtpsy_3391	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Dtpsy_3392	COG0045	succinate-CoA ligase (ADP-forming) activity
Dtpsy_3393	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Dtpsy_3394	COG0758	DNA mediated transformation
Dtpsy_3396	COG0242	peptide deformylase activity
Dtpsy_3398	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Dtpsy_3401	COG0126	phosphoglycerate kinase activity
Dtpsy_3403	COG0284	orotidine-5'-phosphate decarboxylase activity
Dtpsy_3407	COG0840	transmembrane signaling receptor activity
Dtpsy_3408	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Dtpsy_3410	COG2814	Major facilitator Superfamily
Dtpsy_3411	COG0629	single-stranded DNA binding
Dtpsy_3412	COG1620	l-lactate permease
Dtpsy_3413	COG0482	sulfurtransferase activity
Dtpsy_3415	COG1053	succinate dehydrogenase
Dtpsy_3418	COG2204	response regulator
Dtpsy_3419	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Dtpsy_3422	COG0439	Biotin carboxylase
Dtpsy_3423	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Dtpsy_3431	COG0745	RESPONSE REGULATOR receiver
Dtpsy_3433	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Dtpsy_3437	COG1477	protein flavinylation
Dtpsy_3444	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Dtpsy_3446	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Dtpsy_3453	COG1256	bacterial-type flagellum assembly
Dtpsy_3453	COG4786	Flagellar basal body rod
Dtpsy_3457	COG1802	Transcriptional regulator
Dtpsy_3459	COG0559	Belongs to the binding-protein-dependent transport system permease family
Dtpsy_3460	COG4177	L-phenylalanine transmembrane transporter activity
Dtpsy_3462	COG0410	ABC transporter
Dtpsy_3468	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Dtpsy_3469	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Dtpsy_3470	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Dtpsy_3472	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Dtpsy_3475	COG1196	nuclear chromosome segregation
Dtpsy_3477	COG3706	GGDEF domain
Dtpsy_3478	COG2267	carboxylic ester hydrolase activity
Dtpsy_3480	COG3706	GGDEF domain
Dtpsy_3481	COG0840	transmembrane signaling receptor activity
Dtpsy_3482	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Dtpsy_3483	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Dtpsy_3484	COG2119	membrane
Dtpsy_3485	COG0724	RNA recognition motif
Dtpsy_3486	COG0724	RNA recognition motif
Dtpsy_3487	COG0300	oxidoreductase activity
Dtpsy_3489	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Dtpsy_3492	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Dtpsy_3495	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Dtpsy_3497	COG2948	multi-organism process
Dtpsy_3498	COG3504	Conjugal transfer protein
Dtpsy_3503	COG3451	type IV secretory pathway VirB4
Dtpsy_3505	COG3838	Conjugal transfer protein Trbc
Dtpsy_3506	COG4962	Type ii secretion system protein e
Dtpsy_3510	COG0583	DNA-binding transcription factor activity
Dtpsy_3511	COG4566	intracellular signal transduction
Dtpsy_3521	COG4959	Type IV secretory pathway protease TraF
Dtpsy_3524	COG1192	Involved in chromosome partitioning
Dtpsy_3530	COG1396	sequence-specific DNA binding
Dtpsy_3531	COG5489	Protein of unknown function (DUF736)
Dtpsy_3538	COG2003	Belongs to the UPF0758 family
Dtpsy_3539	COG4804	nuclease activity
Dtpsy_3541	COG0747	negative chemotaxis
Dtpsy_3542	COG0706	membrane insertase activity
Dtpsy_3543	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Dtpsy_3544	COG0594	ribonuclease P activity
Dtpsy_3545	COG0230	Belongs to the bacterial ribosomal protein bL34 family