locus-tag	class	description
KI609_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KI609_00115	COG2391	methyltransferase activity
KI609_00120	COG0425	Belongs to the sulfur carrier protein TusA family
KI609_00125	COG0038	chloride channel
KI609_00135	COG1254	Belongs to the acylphosphatase family
KI609_00145	COG1764	response to oxidative stress
KI609_00180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KI609_00205	COG2824	Alkylphosphonate utilization operon protein PhnA
KI609_00225	COG1522	sequence-specific DNA binding
KI609_00230	COG0626	cystathionine gamma-synthase activity
KI609_00235	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_00240	COG2072	flavoprotein involved in K transport
KI609_00250	COG0509	glycine decarboxylation via glycine cleavage system
KI609_00255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KI609_00255	COG1199	ATP-dependent helicase activity
KI609_00275	COG4941	Belongs to the sigma-70 factor family
KI609_00295	COG3795	YCII-related domain
KI609_00300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KI609_00305	COG0791	NLP P60 protein
KI609_00310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KI609_00325	COG3039	Transposase
KI609_00330	COG2974	May be involved in recombination
KI609_00340	COG0789	Transcriptional regulator
KI609_00350	COG2217	Heavy metal translocating P-type atpase
KI609_00355	COG0840	transmembrane signaling receptor activity
KI609_00365	COG1902	pentaerythritol trinitrate reductase activity
KI609_00370	COG0625	glutathione transferase activity
KI609_00390	COG0445	tRNA wobble uridine modification
KI609_00395	COG0357	Ribosomal RNA small subunit methyltransferase G
KI609_00405	COG1192	Involved in chromosome partitioning
KI609_00420	COG1475	DNA binding
KI609_00490	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KI609_00505	COG0277	FAD linked oxidase domain protein
KI609_00525	COG0765	amino acid transport
KI609_00530	COG0765	amino acid transport
KI609_00545	COG2096	Adenosyltransferase
KI609_00550	COG2050	protein possibly involved in aromatic compounds catabolism
KI609_00565	COG2233	PERMEase
KI609_00590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KI609_00610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KI609_00615	COG1960	acyl-CoA dehydrogenase activity
KI609_00620	COG1960	acyl-CoA dehydrogenase activity
KI609_00625	COG1024	Enoyl-CoA hydratase
KI609_00630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KI609_00650	COG1183	phosphatidylcholine synthase activity
KI609_00665	COG0850	regulation of cytokinetic process
KI609_00675	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KI609_00685	COG1289	transmembrane transporter activity
KI609_00695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KI609_00705	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KI609_00710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KI609_00715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KI609_00755	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
KI609_00760	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KI609_00770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KI609_00775	COG3604	Transcriptional regulator
KI609_00780	COG3256	nitric oxide reductase
KI609_00815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KI609_00820	COG0583	DNA-binding transcription factor activity
KI609_00830	COG1960	acyl-CoA dehydrogenase activity
KI609_00845	COG1280	lysine exporter protein (LysE YggA)
KI609_00865	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_00875	COG0183	Belongs to the thiolase family
KI609_00880	COG0427	acetyl-CoA hydrolase
KI609_00885	COG1024	Enoyl-CoA hydratase
KI609_00890	COG2030	dehydratase
KI609_00895	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_00900	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
KI609_00905	COG1960	acyl-CoA dehydrogenase activity
KI609_00930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KI609_00940	COG1024	Enoyl-CoA hydratase
KI609_00945	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_00965	COG0183	Belongs to the thiolase family
KI609_00975	COG1960	acyl-CoA dehydrogenase activity
KI609_00985	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_01000	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_01010	COG0037	tRNA processing
KI609_01015	COG0826	peptidase U32
KI609_01030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KI609_01045	COG2326	polyphosphate kinase activity
KI609_01070	COG0723	plastoquinol--plastocyanin reductase activity
KI609_01080	COG0646	methionine synthase
KI609_01080	COG1410	methionine synthase
KI609_01085	COG0251	oxidation-reduction process
KI609_01100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KI609_01125	COG1295	ribonuclease BN
KI609_01140	COG1309	transcriptional regulator
KI609_01170	COG0683	leucine binding
KI609_01190	COG2080	2 iron, 2 sulfur cluster binding
KI609_01195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KI609_01195	COG2010	Cytochrome c
KI609_01210	COG1522	sequence-specific DNA binding
KI609_01225	COG0653	protein targeting
KI609_01230	COG2826	transposase and inactivated derivatives, IS30 family
KI609_01235	COG1960	acyl-CoA dehydrogenase activity
KI609_01255	COG1024	Enoyl-CoA hydratase
KI609_01270	COG0583	DNA-binding transcription factor activity
KI609_01275	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_01280	COG0606	chelatase, subunit chli
KI609_01290	COG0347	Belongs to the P(II) protein family
KI609_01295	COG0004	ammonium transporteR
KI609_01300	COG0277	FAD linked oxidase domain protein
KI609_01310	COG0247	lactate metabolic process
KI609_01315	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KI609_01335	COG0386	Belongs to the glutathione peroxidase family
KI609_01350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KI609_01390	COG0747	negative chemotaxis
KI609_01395	COG0625	glutathione transferase activity
KI609_01400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KI609_01445	COG1216	Glycosyl transferase, family 2
KI609_01465	COG0477	Major facilitator Superfamily
KI609_01480	COG2211	Major facilitator Superfamily
KI609_01485	COG4783	chaperone-mediated protein folding
KI609_01495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KI609_01500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KI609_01505	COG0708	Exodeoxyribonuclease III
KI609_01510	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KI609_01520	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KI609_01525	COG0154	amidase activity
KI609_01530	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KI609_01535	COG1077	Cell shape determining protein MreB Mrl
KI609_01545	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KI609_01550	COG0768	penicillin binding
KI609_01565	COG0765	amino acid transport
KI609_01570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KI609_01580	COG0004	ammonium transporteR
KI609_01595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KI609_01600	COG1127	ABC transporter
KI609_01650	COG4452	Inner membrane protein CreD
KI609_01660	COG2205	protein histidine kinase activity
KI609_01665	COG0745	RESPONSE REGULATOR receiver
KI609_01670	COG2095	MarC family integral membrane protein
KI609_01675	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_01680	COG0412	Dienelactone hydrolase
KI609_01685	COG0598	Magnesium transport protein CorA
KI609_01695	COG1981	membrane
KI609_01710	COG2945	thiolester hydrolase activity
KI609_01715	COG1686	Belongs to the peptidase S11 family
KI609_01720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KI609_01725	COG0049	tRNA binding
KI609_01730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KI609_01735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KI609_01740	COG0051	transcription antitermination factor activity, RNA binding
KI609_01745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KI609_01750	COG0088	Forms part of the polypeptide exit tunnel
KI609_01755	COG0089	rRNA binding
KI609_01760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KI609_01765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KI609_01770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KI609_01775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KI609_01780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KI609_01785	COG0255	Belongs to the universal ribosomal protein uL29 family
KI609_01790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KI609_01795	COG0678	peroxiredoxin activity
KI609_01815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KI609_01835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KI609_01840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KI609_01860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KI609_01865	COG0321	lipoyl(octanoyl) transferase activity
KI609_01870	COG2921	Belongs to the UPF0250 family
KI609_01880	COG0356	it plays a direct role in the translocation of protons across the membrane
KI609_01890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KI609_01895	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KI609_01900	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KI609_01905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KI609_01910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KI609_01915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KI609_01950	COG3245	cytochrome
KI609_01960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KI609_01965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KI609_01970	COG1309	transcriptional regulator
KI609_01995	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KI609_02005	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KI609_02015	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KI609_02020	COG0081	regulation of translation
KI609_02025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KI609_02030	COG0222	ribosome binding
KI609_02035	COG0085	RNA polymerase activity
KI609_02040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KI609_02050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KI609_02050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KI609_02060	COG5000	phosphorelay sensor kinase activity
KI609_02065	COG2204	response regulator
KI609_02090	COG0667	Aldo Keto reductase
KI609_02100	COG0667	Aldo Keto reductase
KI609_02125	COG3550	peptidyl-serine autophosphorylation
KI609_02135	COG0443	Heat shock 70 kDa protein
KI609_02140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KI609_02145	COG0792	nuclease activity
KI609_02150	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KI609_02155	COG2823	Periplasmic or secreted lipoprotein
KI609_02160	COG3385	transposase activity
KI609_02165	COG2084	Dehydrogenase
KI609_02175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KI609_02185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KI609_02205	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_02210	COG4770	biotin carboxylase activity
KI609_02220	COG2733	membrane
KI609_02235	COG0724	RNA recognition motif
KI609_02240	COG1346	cytolysis
KI609_02245	COG1380	Effector of murein hydrolase LrgA
KI609_02250	COG0277	FAD linked oxidase domain protein
KI609_02260	COG0583	DNA-binding transcription factor activity
KI609_02280	COG3850	Histidine kinase
KI609_02285	COG2197	response regulator
KI609_02295	COG2223	nitrite transmembrane transporter activity
KI609_02300	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KI609_02305	COG1140	nitrate reductase beta subunit
KI609_02310	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KI609_02315	COG2181	nitrate reductase activity
KI609_02325	COG0288	reversible hydration of carbon dioxide
KI609_02350	COG3945	hemerythrin HHE cation binding domain
KI609_02380	COG3039	Transposase
KI609_02400	COG1309	transcriptional regulator
KI609_02405	COG1979	alcohol dehydrogenase
KI609_02415	COG0583	DNA-binding transcription factor activity
KI609_02420	COG1741	Belongs to the pirin family
KI609_02425	COG1335	isochorismatase
KI609_02450	COG0243	molybdopterin cofactor binding
KI609_02465	COG1473	amidohydrolase
KI609_02485	COG4948	Mandelate Racemase Muconate Lactonizing
KI609_02490	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_02500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KI609_02505	COG0583	DNA-binding transcription factor activity
KI609_02525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KI609_02530	COG2423	ornithine cyclodeaminase activity
KI609_02550	COG2818	Glycosylase
KI609_02560	COG1393	Belongs to the ArsC family
KI609_02565	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KI609_02570	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KI609_02575	COG1609	Transcriptional regulator
KI609_02580	COG3624	Phosphonate C-P lyase system protein PhnG
KI609_02585	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
KI609_02590	COG3626	phosphonate metabolism
KI609_02595	COG3627	carbon phosphorus lyase activity
KI609_02605	COG4107	phosphonate C-P lyase system protein PhnK
KI609_02610	COG4778	phosphonate C-P lyase system protein PhnL
KI609_02615	COG3454	Phosphonate metabolism
KI609_02625	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KI609_02630	COG3639	organic phosphonate transmembrane transporter activity
KI609_02645	COG0697	spore germination
KI609_02660	COG1960	acyl-CoA dehydrogenase activity
KI609_02665	COG1024	Enoyl-CoA hydratase
KI609_02680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KI609_02735	COG3267	Type II secretory pathway component ExeA
KI609_02735	COG3409	Peptidoglycan-binding domain 1 protein
KI609_02750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KI609_02755	COG0840	transmembrane signaling receptor activity
KI609_02770	COG1187	pseudouridine synthase activity
KI609_02785	COG0326	Molecular chaperone. Has ATPase activity
KI609_02800	COG1653	transport
KI609_02820	COG0745	RESPONSE REGULATOR receiver
KI609_02825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KI609_02835	COG0515	serine threonine protein kinase
KI609_02835	COG2815	serine threonine protein kinase
KI609_02845	COG1764	response to oxidative stress
KI609_02850	COG1846	Transcriptional regulator
KI609_02855	COG1024	Enoyl-CoA hydratase
KI609_02860	COG1250	3-hydroxyacyl-CoA dehydrogenase
KI609_02875	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KI609_02880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KI609_02890	COG0513	Belongs to the DEAD box helicase family
KI609_02895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KI609_02900	COG1490	D-aminoacyl-tRNA deacylase activity
KI609_02910	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KI609_02925	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KI609_02930	COG1845	cytochrome c oxidase, subunit III
KI609_02935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KI609_02940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KI609_02945	COG0477	Major facilitator Superfamily
KI609_02950	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KI609_02955	COG1702	phosphate starvation-inducible protein PhoH
KI609_02960	COG0632	four-way junction helicase activity
KI609_02970	COG2255	four-way junction helicase activity
KI609_02980	COG4591	ABC-type transport system involved in lipoprotein release permease component
KI609_02985	COG1136	(ABC) transporter
KI609_02995	COG3616	Alanine racemase, N-terminal domain
KI609_03010	COG0037	tRNA processing
KI609_03025	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_03040	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KI609_03045	COG3387	PFAM Glycoside hydrolase 15-related
KI609_03050	COG1877	trehalose-phosphatase activity
KI609_03070	COG3220	belongs to the UPF0276 family
KI609_03080	COG1595	DNA-templated transcription, initiation
KI609_03085	COG4944	Protein of unknown function (DUF1109)
KI609_03090	COG0617	tRNA 3'-terminal CCA addition
KI609_03105	COG0625	glutathione transferase activity
KI609_03110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KI609_03125	COG1869	D-ribose catabolic process
KI609_03140	COG1172	Belongs to the binding-protein-dependent transport system permease family
KI609_03145	COG1129	ABC transporter
KI609_03150	COG1879	ABC-type sugar transport system periplasmic component
KI609_03155	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_03170	COG3186	Phenylalanine-4-hydroxylase
KI609_03190	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KI609_03195	COG1522	sequence-specific DNA binding
KI609_03205	COG4535	Mg2 and Co2 transporter CorC
KI609_03210	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KI609_03215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KI609_03225	COG0583	DNA-binding transcription factor activity
KI609_03235	COG0752	glycyl-tRNA synthetase alpha subunit
KI609_03240	COG0751	glycine-tRNA ligase activity
KI609_03245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KI609_03265	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KI609_03285	COG4221	oxidoreductase activity
KI609_03315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KI609_03320	COG1459	type II secretion system
KI609_03325	COG2165	general secretion pathway protein
KI609_03335	COG2165	general secretion pathway protein
KI609_03340	COG4795	General secretion pathway protein
KI609_03365	COG1450	Type ii and iii secretion system protein
KI609_03380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KI609_03415	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KI609_03430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KI609_03435	COG0745	RESPONSE REGULATOR receiver
KI609_03440	COG0642	Histidine kinase
KI609_03445	COG1309	transcriptional regulator
KI609_03455	COG1960	acyl-CoA dehydrogenase activity
KI609_03465	COG1250	3-hydroxyacyl-CoA dehydrogenase
KI609_03465	COG1024	Enoyl-CoA hydratase
KI609_03475	COG0183	Belongs to the thiolase family
KI609_03490	COG1024	Enoyl-CoA hydratase
KI609_03500	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_03505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KI609_03510	COG4335	DNA alkylation repair
KI609_03515	COG1960	acyl-CoA dehydrogenase activity
KI609_03520	COG1024	Enoyl-CoA hydratase
KI609_03530	COG1960	acyl-CoA dehydrogenase activity
KI609_03535	COG3246	L-lysine catabolic process to acetate
KI609_03550	COG3039	Transposase
KI609_03560	COG0183	Belongs to the thiolase family
KI609_03570	COG1960	acyl-CoA dehydrogenase activity
KI609_03580	COG1022	Amp-dependent synthetase and ligase
KI609_03615	COG1607	acyl-coa hydrolase
KI609_03620	COG5265	(ABC) transporter
KI609_03625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KI609_03635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KI609_03640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KI609_03650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KI609_03655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KI609_03655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KI609_03665	COG0583	DNA-binding transcription factor activity
KI609_03675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KI609_03680	COG0765	amino acid transport
KI609_03685	COG0765	amino acid transport
KI609_03690	COG1126	abc transporter atp-binding protein
KI609_03695	COG0418	dihydroorotase activity
KI609_03705	COG0501	Belongs to the peptidase M48B family
KI609_03710	COG0840	transmembrane signaling receptor activity
KI609_03715	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KI609_03720	COG0392	lysyltransferase activity
KI609_03725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KI609_03730	COG3568	Endonuclease Exonuclease Phosphatase
KI609_03740	COG2226	methyltransferase
KI609_03770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KI609_03775	COG0656	L-ascorbic acid biosynthetic process
KI609_03780	COG2814	Major facilitator Superfamily
KI609_03785	COG0583	DNA-binding transcription factor activity
KI609_03795	COG0625	glutathione transferase activity
KI609_03800	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KI609_03810	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KI609_03815	COG5001	Diguanylate cyclase
KI609_03820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KI609_03825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KI609_03840	COG0523	cobalamin synthesis protein
KI609_03855	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KI609_03860	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KI609_03865	COG2001	Belongs to the MraZ family
KI609_03870	COG0275	rRNA processing
KI609_03885	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KI609_03890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KI609_03895	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KI609_03900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KI609_03905	COG0772	Belongs to the SEDS family
KI609_03910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KI609_03915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KI609_03920	COG1181	Belongs to the D-alanine--D-alanine ligase family
KI609_03925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KI609_03935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KI609_03945	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KI609_03955	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KI609_03960	COG0840	transmembrane signaling receptor activity
KI609_04025	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KI609_04030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KI609_04035	COG1765	OsmC-like protein
KI609_04040	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KI609_04060	COG1473	amidohydrolase
KI609_04070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KI609_04075	COG0444	Belongs to the ABC transporter superfamily
KI609_04080	COG4608	Belongs to the ABC transporter superfamily
KI609_04095	COG1840	ABC-type Fe3 transport system, periplasmic component
KI609_04105	COG3842	ATPase activity
KI609_04110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KI609_04135	COG1175	transmembrane transport
KI609_04140	COG0395	ABC-type sugar transport system, permease component
KI609_04145	COG3842	ATPase activity
KI609_04150	COG0837	glucose binding
KI609_04155	COG0346	lactoylglutathione lyase activity
KI609_04160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KI609_04165	COG0166	Belongs to the GPI family
KI609_04180	COG0129	dihydroxy-acid dehydratase activity
KI609_04185	COG0800	Aldolase
KI609_04215	COG1272	protein, Hemolysin III
KI609_04240	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_04245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KI609_04250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KI609_04260	COG0557	exoribonuclease II activity
KI609_04270	COG1595	DNA-templated transcription, initiation
KI609_04280	COG3474	cytochrome
KI609_04295	COG3150	esterase
KI609_04300	COG0515	serine threonine protein kinase
KI609_04300	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KI609_04305	COG0772	Belongs to the SEDS family
KI609_04310	COG0312	modulator of DNA gyrase
KI609_04320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KI609_04330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KI609_04340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KI609_04345	COG0511	ligase activity, forming carbon-carbon bonds
KI609_04350	COG0439	Biotin carboxylase
KI609_04355	COG2264	protein methyltransferase activity
KI609_04370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KI609_04385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KI609_04420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KI609_04425	COG2943	transferase activity, transferring hexosyl groups
KI609_04430	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KI609_04435	COG2204	response regulator
KI609_04445	COG2205	protein histidine kinase activity
KI609_04450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KI609_04465	COG1024	Enoyl-CoA hydratase
KI609_04480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KI609_04485	COG0633	Ferredoxin
KI609_04485	COG3217	Mosc domain protein beta barrel domain protein
KI609_04490	COG0012	GTP binding
KI609_04500	COG1136	(ABC) transporter
KI609_04500	COG0577	efflux transmembrane transporter activity
KI609_04520	COG1238	metal cluster binding
KI609_04530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KI609_04535	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KI609_04540	COG0138	bifunctional purine biosynthesis protein purh
KI609_04550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KI609_04555	COG1414	Transcriptional regulator
KI609_04560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KI609_04565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KI609_04565	COG0351	phosphomethylpyrimidine kinase
KI609_04565	COG0352	thiamine-phosphate diphosphorylase activity
KI609_04570	COG1773	rubredoxin
KI609_04585	COG0835	chemotaxis
KI609_04595	COG0643	Histidine kinase
KI609_04595	COG0784	Response regulator, receiver
KI609_04595	COG2198	Histidine kinase
KI609_04605	COG0415	Belongs to the DNA photolyase family
KI609_04610	COG1678	Uncharacterized ACR, COG1678
KI609_04615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KI609_04620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KI609_04625	COG0540	Belongs to the ATCase OTCase family
KI609_04630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KI609_04645	COG3842	ATPase activity
KI609_04650	COG1178	ABC-type Fe3 transport system permease component
KI609_04655	COG4999	Histidine kinase
KI609_04655	COG3850	Histidine kinase
KI609_04655	COG3437	response regulator, receiver
KI609_04655	COG2205	protein histidine kinase activity
KI609_04665	COG4773	Receptor
KI609_04675	COG1012	belongs to the aldehyde dehydrogenase family
KI609_04680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KI609_04690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KI609_04700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KI609_04720	COG2706	6-phosphogluconolactonase activity
KI609_04725	COG2721	sulfolactate sulfo-lyase activity
KI609_04740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KI609_04750	COG0642	Histidine kinase
KI609_04760	COG1522	sequence-specific DNA binding
KI609_04765	COG5006	permease, DMT superfamily
KI609_04805	COG0582	viral genome integration into host DNA
KI609_04915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KI609_04940	COG1414	Transcriptional regulator
KI609_04950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KI609_04955	COG0183	Belongs to the thiolase family
KI609_04960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KI609_04980	COG2031	fatty acid transporter
KI609_04990	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_05000	COG0583	DNA-binding transcription factor activity
KI609_05015	COG2860	membrane
KI609_05035	COG4774	siderophore transport
KI609_05040	COG0475	glutathione-regulated potassium exporter activity
KI609_05040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KI609_05045	COG1280	lysine exporter protein (LysE YggA)
KI609_05065	COG0583	DNA-binding transcription factor activity
KI609_05070	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KI609_05080	COG2226	methyltransferase
KI609_05095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KI609_05105	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KI609_05115	COG1845	cytochrome c oxidase, subunit III
KI609_05140	COG0109	protoheme IX farnesyltransferase activity
KI609_05145	COG1999	signal sequence binding
KI609_05150	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_05155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KI609_05170	COG0612	Peptidase, M16
KI609_05175	COG0612	Peptidase, M16
KI609_05180	COG0742	ribosomal rna small subunit methyltransferase
KI609_05185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KI609_05190	COG0583	DNA-binding transcription factor activity
KI609_05200	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KI609_05205	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KI609_05220	COG0588	phosphoglycerate mutase activity
KI609_05225	COG0793	Belongs to the peptidase S41A family
KI609_05230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KI609_05240	COG2197	response regulator
KI609_05245	COG4585	Histidine kinase
KI609_05250	COG5487	UPF0391 membrane protein
KI609_05260	COG0783	Belongs to the Dps family
KI609_05275	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KI609_05280	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KI609_05290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KI609_05310	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KI609_05330	COG0028	Belongs to the TPP enzyme family
KI609_05345	COG0659	secondary active sulfate transmembrane transporter activity
KI609_05360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KI609_05360	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KI609_05375	COG0489	protein tyrosine kinase activity
KI609_05385	COG3383	formate dehydrogenase (NAD+) activity
KI609_05415	COG0243	molybdopterin cofactor binding
KI609_05415	COG3383	formate dehydrogenase (NAD+) activity
KI609_05420	COG0437	4 iron, 4 sulfur cluster binding
KI609_05440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KI609_05460	COG2346	COG2346, Truncated hemoglobins
KI609_05465	COG1704	LemA family
KI609_05470	COG0501	Belongs to the peptidase M48B family
KI609_05485	COG0737	Belongs to the 5'-nucleotidase family
KI609_05490	COG1193	negative regulation of DNA recombination
KI609_05495	COG2003	Belongs to the UPF0758 family
KI609_05500	COG1047	Peptidyl-prolyl cis-trans
KI609_05505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KI609_05510	COG0517	IMP dehydrogenase activity
KI609_05510	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KI609_05510	COG0617	tRNA 3'-terminal CCA addition
KI609_05515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KI609_05520	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KI609_05535	COG2974	May be involved in recombination
KI609_05575	COG0629	single-stranded DNA binding
KI609_05670	COG1484	DNA-dependent DNA replication
KI609_05855	COG0582	viral genome integration into host DNA
KI609_05880	COG2003	Belongs to the UPF0758 family
KI609_05950	COG0583	DNA-binding transcription factor activity
KI609_05955	COG0709	Synthesizes selenophosphate from selenide and ATP
KI609_05960	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KI609_05975	COG0745	RESPONSE REGULATOR receiver
KI609_05985	COG0180	Tryptophanyl-tRNA synthetase
KI609_05990	COG1994	Peptidase M50
KI609_06000	COG0009	L-threonylcarbamoyladenylate synthase
KI609_06005	COG0613	PHP domain protein
KI609_06010	COG0840	transmembrane signaling receptor activity
KI609_06015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KI609_06025	COG4591	ABC-type transport system involved in lipoprotein release permease component
KI609_06030	COG1136	(ABC) transporter
KI609_06035	COG2304	oxidoreductase activity
KI609_06045	COG0714	Associated with various cellular activities
KI609_06050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KI609_06055	COG0084	hydrolase, TatD family'
KI609_06075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KI609_06110	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_06115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KI609_06130	COG1742	UPF0060 membrane protein
KI609_06135	COG0697	spore germination
KI609_06150	COG0702	epimerase
KI609_06160	COG0583	DNA-binding transcription factor activity
KI609_06170	COG1283	sodium-dependent phosphate transmembrane transporter activity
KI609_06175	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KI609_06180	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KI609_06185	COG0196	riboflavin kinase activity
KI609_06195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KI609_06225	COG1960	acyl-CoA dehydrogenase activity
KI609_06230	COG1960	acyl-CoA dehydrogenase activity
KI609_06235	COG3132	Protein of unknown function, DUF480
KI609_06240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KI609_06270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KI609_06270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KI609_06280	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KI609_06285	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KI609_06290	COG0492	ferredoxin-NADP+ reductase activity
KI609_06300	COG1674	ftsk spoiiie
KI609_06305	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KI609_06310	COG1573	uracil-dna glycosylase
KI609_06320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KI609_06325	COG0559	Belongs to the binding-protein-dependent transport system permease family
KI609_06350	COG1392	Phosphate transport regulator
KI609_06355	COG0306	phosphate transporter
KI609_06370	COG0228	four-way junction DNA binding
KI609_06375	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KI609_06380	COG0336	Belongs to the RNA methyltransferase TrmD family
KI609_06385	COG0335	large ribosomal subunit rRNA binding
KI609_06395	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KI609_06400	COG1162	GTPase activity
KI609_06405	COG2154	pterin-4-alpha-carbinolamine dehydratase
KI609_06415	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KI609_06420	COG0513	Belongs to the DEAD box helicase family
KI609_06425	COG5002	protein histidine kinase activity
KI609_06425	COG5001	Diguanylate cyclase
KI609_06425	COG3447	MASE1 domain protein
KI609_06430	COG2814	Major facilitator Superfamily
KI609_06440	COG2084	Dehydrogenase
KI609_06450	COG0516	GMP reductase activity
KI609_06460	COG0210	DNA helicase
KI609_06505	COG2885	chlorophyll binding
KI609_06550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KI609_06570	COG5265	(ABC) transporter
KI609_06575	COG2814	Major facilitator Superfamily
KI609_06590	COG0604	alcohol dehydrogenase
KI609_06590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KI609_06590	COG3321	synthase
KI609_06590	COG4221	oxidoreductase activity
KI609_06600	COG0625	glutathione transferase activity
KI609_06620	COG5001	Diguanylate cyclase
KI609_06620	COG2203	Gaf domain
KI609_06620	COG4251	negative regulation of phosphorylation
KI609_06620	COG3706	GGDEF domain
KI609_06625	COG0412	Dienelactone hydrolase
KI609_06645	COG3039	Transposase
KI609_06650	COG0251	oxidation-reduction process
KI609_06675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KI609_06680	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_06695	COG3275	phosphorelay sensor kinase activity
KI609_06700	COG0165	Argininosuccinate lyase
KI609_06710	COG0840	transmembrane signaling receptor activity
KI609_06720	COG0753	catalase activity
KI609_06755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KI609_06760	COG5001	Diguanylate cyclase
KI609_06760	COG3447	MASE1 domain protein
KI609_06760	COG5002	protein histidine kinase activity
KI609_06765	COG1304	FMN binding
KI609_06770	COG1595	DNA-templated transcription, initiation
KI609_06805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KI609_06820	COG1177	transmembrane transport
KI609_06825	COG1176	ABC-type spermidine putrescine transport system, permease component I
KI609_06830	COG3842	ATPase activity
KI609_06835	COG1414	Transcriptional regulator
KI609_06870	COG1012	belongs to the aldehyde dehydrogenase family
KI609_06880	COG0436	Aminotransferase
KI609_06885	COG0028	Belongs to the TPP enzyme family
KI609_06900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KI609_06905	COG0840	transmembrane signaling receptor activity
KI609_06915	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KI609_06915	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KI609_06925	COG3022	response to hydroperoxide
KI609_06930	COG1530	ribonuclease E activity
KI609_06950	COG0616	signal peptide processing
KI609_06950	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KI609_06955	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KI609_06960	COG0424	maF-like protein
KI609_06965	COG1399	metal-binding, possibly nucleic acid-binding protein
KI609_06970	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KI609_06975	COG0416	fatty acid biosynthetic process
KI609_06980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KI609_06985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KI609_06990	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_06995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KI609_07000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KI609_07025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KI609_07035	COG0481	GTPase activity
KI609_07050	COG0571	ribonuclease III activity
KI609_07055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KI609_07060	COG1381	Involved in DNA repair and RecF pathway recombination
KI609_07065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KI609_07070	COG0736	holo-[acyl-carrier-protein] synthase activity
KI609_07075	COG1472	Belongs to the glycosyl hydrolase 3 family
KI609_07100	COG0745	RESPONSE REGULATOR receiver
KI609_07105	COG2205	protein histidine kinase activity
KI609_07110	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KI609_07115	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KI609_07120	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KI609_07130	COG0598	Magnesium transport protein CorA
KI609_07140	COG3158	transport of potassium into the cell
KI609_07170	COG1902	pentaerythritol trinitrate reductase activity
KI609_07175	COG1309	transcriptional regulator
KI609_07215	COG3706	GGDEF domain
KI609_07220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KI609_07240	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KI609_07245	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KI609_07250	COG0367	asparagine synthase
KI609_07290	COG2089	acid synthase
KI609_07300	COG1083	cytidylyl-transferase
KI609_07310	COG1086	Polysaccharide biosynthesis protein
KI609_07325	COG0762	integral membrane protein
KI609_07330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KI609_07335	COG0159	tryptophan synthase activity
KI609_07340	COG0133	tryptophan synthase activity
KI609_07345	COG0135	phosphoribosylanthranilate isomerase activity
KI609_07350	COG0101	tRNA pseudouridine synthase activity
KI609_07360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KI609_07365	COG0473	3-isopropylmalate dehydrogenase activity
KI609_07370	COG0066	3-isopropylmalate dehydratase activity
KI609_07380	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KI609_07390	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KI609_07395	COG0484	heat shock protein binding
KI609_07400	COG0443	Heat shock 70 kDa protein
KI609_07405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KI609_07410	COG0360	Binds together with S18 to 16S ribosomal RNA
KI609_07420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KI609_07425	COG0359	binds to the 23S rRNA
KI609_07440	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KI609_07445	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KI609_07455	COG0436	Aminotransferase
KI609_07465	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KI609_07470	COG1763	Mo-molybdopterin cofactor biosynthetic process
KI609_07475	COG0303	'Molybdopterin
KI609_07505	COG0314	molybdopterin synthase activity
KI609_07510	COG0542	response to heat
KI609_07525	COG0784	Response regulator, receiver
KI609_07525	COG2198	Histidine kinase
KI609_07525	COG2205	protein histidine kinase activity
KI609_07530	COG2197	response regulator
KI609_07550	COG2264	protein methyltransferase activity
KI609_07565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KI609_07570	COG0004	ammonium transporteR
KI609_07605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KI609_07605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KI609_07610	COG0436	Aminotransferase
KI609_07615	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KI609_07620	COG1185	polyribonucleotide nucleotidyltransferase activity
KI609_07625	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_07625	COG3321	synthase
KI609_07625	COG0604	alcohol dehydrogenase
KI609_07630	COG0149	triose-phosphate isomerase activity
KI609_07645	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KI609_07650	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KI609_07655	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KI609_07660	COG0649	NAD binding
KI609_07665	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KI609_07670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KI609_07675	COG1034	ATP synthesis coupled electron transport
KI609_07680	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KI609_07685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KI609_07695	COG0713	ATP synthesis coupled electron transport
KI609_07710	COG1007	ATP synthesis coupled electron transport
KI609_07725	COG1132	(ABC) transporter
KI609_07765	COG3039	Transposase
KI609_07770	COG0584	glycerophosphoryl diester phosphodiesterase
KI609_07775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KI609_07780	COG2267	carboxylic ester hydrolase activity
KI609_07790	COG2814	Major facilitator Superfamily
KI609_07795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KI609_07800	COG4181	ATPase activity
KI609_07805	COG0071	Belongs to the small heat shock protein (HSP20) family
KI609_07825	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KI609_07830	COG0586	Pfam SNARE associated Golgi protein
KI609_07845	COG0860	N-Acetylmuramoyl-L-alanine amidase
KI609_07855	COG0802	atpase or kinase
KI609_07860	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KI609_07865	COG2755	lipolytic protein G-D-S-L family
KI609_07880	COG4974	Belongs to the 'phage' integrase family
KI609_07885	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KI609_07890	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KI609_07895	COG2833	Protein of unknown function (DUF455)
KI609_07905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KI609_07915	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KI609_07920	COG0148	phosphopyruvate hydratase activity
KI609_07935	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KI609_07940	COG0504	CTP synthase activity
KI609_07945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KI609_07950	COG0756	dUTP diphosphatase activity
KI609_07960	COG1047	Peptidyl-prolyl cis-trans
KI609_07965	COG2850	peptidyl-arginine hydroxylation
KI609_07980	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KI609_07985	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KI609_07990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KI609_08020	COG0840	transmembrane signaling receptor activity
KI609_08035	COG2308	Evidence 4 Homologs of previously reported genes of
KI609_08050	COG4628	conserved protein (DUF2132)
KI609_08060	COG0657	acetylesterase activity
KI609_08095	COG4774	siderophore transport
KI609_08285	COG3634	alkyl hydroperoxide reductase activity
KI609_08290	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KI609_08305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KI609_08325	COG0583	DNA-binding transcription factor activity
KI609_08330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KI609_08335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KI609_08350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KI609_08355	COG0358	DNA primase activity
KI609_08360	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KI609_08370	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_08375	COG3540	Alkaline phosphatase
KI609_08385	COG3321	synthase
KI609_08385	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_08385	COG0604	alcohol dehydrogenase
KI609_08390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KI609_08395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KI609_08410	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KI609_08415	COG1187	pseudouridine synthase activity
KI609_08420	COG0105	UTP biosynthetic process
KI609_08425	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KI609_08440	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KI609_08445	COG0124	histidyl-tRNA synthetase
KI609_08455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KI609_08460	COG1160	GTP binding
KI609_08465	COG1923	regulation of RNA biosynthetic process
KI609_08470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KI609_08475	COG0330	HflC and HflK could
KI609_08480	COG0330	HflC and HflK could
KI609_08485	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KI609_08490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KI609_08555	COG0174	glutamine synthetase
KI609_08565	COG3852	Histidine kinase
KI609_08580	COG0708	Exodeoxyribonuclease III
KI609_08585	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KI609_08595	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KI609_08605	COG1175	transmembrane transport
KI609_08610	COG0395	ABC-type sugar transport system, permease component
KI609_08625	COG0246	Mannitol dehydrogenase
KI609_08630	COG2207	Transcriptional regulator
KI609_08635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KI609_08660	COG0277	FAD linked oxidase domain protein
KI609_08670	COG1295	ribonuclease BN
KI609_08680	COG2267	carboxylic ester hydrolase activity
KI609_08695	COG2202	Pas domain
KI609_08695	COG2200	EAL domain
KI609_08695	COG2199	diguanylate cyclase activity
KI609_08700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KI609_08705	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KI609_08710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KI609_08715	COG0741	lytic transglycosylase activity
KI609_08735	COG0557	exoribonuclease II activity
KI609_08740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KI609_08740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KI609_08745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KI609_08755	COG0052	Belongs to the universal ribosomal protein uS2 family
KI609_08760	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KI609_08765	COG0528	UMP kinase activity
KI609_08770	COG0233	cytoplasmic translational termination
KI609_08785	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KI609_08790	COG0750	zinc metalloprotease
KI609_08805	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KI609_08810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KI609_08815	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KI609_08820	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KI609_08825	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KI609_08830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KI609_08835	COG0505	Belongs to the CarA family
KI609_08840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KI609_08845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KI609_08860	COG1534	Rna-binding protein
KI609_08865	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KI609_08870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KI609_08880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KI609_08930	COG0573	inorganic phosphate transmembrane transporter activity
KI609_08935	COG0581	inorganic phosphate transmembrane transporter activity
KI609_08940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KI609_08950	COG0745	RESPONSE REGULATOR receiver
KI609_08960	COG0534	Mate efflux family protein
KI609_08970	COG0254	rRNA binding
KI609_08975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KI609_09025	COG0492	ferredoxin-NADP+ reductase activity
KI609_09040	COG0583	DNA-binding transcription factor activity
KI609_09055	COG3039	Transposase
KI609_09075	COG2826	transposase and inactivated derivatives, IS30 family
KI609_09090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KI609_09095	COG2235	arginine
KI609_09100	COG1288	antiporter activity
KI609_09110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KI609_09165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KI609_09205	COG3039	Transposase
KI609_09215	COG1940	carbohydrate kinase activity
KI609_09220	COG1129	ABC transporter
KI609_09225	COG1172	Belongs to the binding-protein-dependent transport system permease family
KI609_09230	COG1879	ABC-type sugar transport system periplasmic component
KI609_09240	COG0673	inositol 2-dehydrogenase activity
KI609_09285	COG3267	Type II secretory pathway component ExeA
KI609_09285	COG3409	Peptidoglycan-binding domain 1 protein
KI609_09290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KI609_09295	COG1459	type II secretion system
KI609_09335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KI609_09340	COG2863	cytochrome
KI609_09355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KI609_09360	COG0779	Required for maturation of 30S ribosomal subunits
KI609_09365	COG0195	Participates in both transcription termination and antitermination
KI609_09370	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KI609_09375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KI609_09380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KI609_09395	COG1024	Enoyl-CoA hydratase
KI609_09420	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KI609_09430	COG2914	Belongs to the UPF0125 (RnfH) family
KI609_09445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KI609_09445	COG0519	Catalyzes the synthesis of GMP from XMP
KI609_09450	COG0582	viral genome integration into host DNA
KI609_09485	COG4771	TonB-dependent receptor
KI609_09490	COG1429	ligase activity, forming nitrogen-metal bonds
KI609_09505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KI609_09510	COG1116	anion transmembrane transporter activity
KI609_09520	COG4178	(ABC) transporter
KI609_09545	COG0840	transmembrane signaling receptor activity
KI609_09555	COG0745	RESPONSE REGULATOR receiver
KI609_09630	COG3916	Acyl-homoserine-lactone synthase
KI609_09675	COG5489	Protein of unknown function (DUF736)
KI609_09680	COG1396	sequence-specific DNA binding
KI609_09705	COG1192	Involved in chromosome partitioning
KI609_09720	COG4959	Type IV secretory pathway protease TraF
KI609_09735	COG3135	benzoate transporter
KI609_09740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KI609_09745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KI609_09755	COG4206	TonB-dependent receptor
KI609_09775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KI609_09780	COG1120	ATPase activity
KI609_09785	COG0500	methyltransferase
KI609_09795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KI609_09800	COG1120	ATPase activity
KI609_09840	COG4149	molybdate abc transporter
KI609_09850	COG0583	DNA-binding transcription factor activity
KI609_09885	COG0210	DNA helicase
KI609_09955	COG1793	dna ligase
KI609_09965	COG4166	transmembrane transport
KI609_09970	COG4174	ABC transporter (Permease)
KI609_09985	COG4239	(ABC) transporter, permease
KI609_09990	COG4172	Belongs to the ABC transporter superfamily
KI609_10045	COG2826	transposase and inactivated derivatives, IS30 family
KI609_10070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KI609_10070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KI609_10070	COG0506	proline dehydrogenase activity
KI609_10085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KI609_10100	COG3193	protein, possibly involved in utilization of glycolate and propanediol
KI609_10135	COG3128	pkhd-type hydroxylase
KI609_10150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KI609_10170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KI609_10175	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KI609_10180	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KI609_10185	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KI609_10190	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KI609_10195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KI609_10195	COG0072	phenylalanine-tRNA ligase activity
KI609_10200	COG0776	regulation of translation
KI609_10205	COG0789	Transcriptional regulator
KI609_10235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KI609_10240	COG0308	aminopeptidase N
KI609_10245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KI609_10295	COG2267	carboxylic ester hydrolase activity
KI609_10300	COG0667	Aldo Keto reductase
KI609_10315	COG0583	DNA-binding transcription factor activity
KI609_10320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KI609_10325	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KI609_10335	COG3577	Aspartyl protease
KI609_10340	COG1666	GTP binding
KI609_10345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KI609_10350	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KI609_10355	COG0137	argininosuccinate synthase activity
KI609_10360	COG3123	guanosine phosphorylase activity
KI609_10370	COG1393	Belongs to the ArsC family
KI609_10375	COG0285	dihydrofolate synthase activity
KI609_10395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KI609_10465	COG1840	ABC-type Fe3 transport system, periplasmic component
KI609_10480	COG0123	including yeast histone deacetylase and acetoin utilization protein
KI609_10490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KI609_10515	COG1611	Belongs to the LOG family
KI609_10525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KI609_10555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KI609_10560	COG0601	transmembrane transport
KI609_10565	COG4166	transmembrane transport
KI609_10570	COG4172	Belongs to the ABC transporter superfamily
KI609_10590	COG2212	antiporter activity
KI609_10595	COG1863	multisubunit Na H antiporter MnhE subunit
KI609_10600	COG0651	ATP synthesis coupled electron transport
KI609_10605	COG1006	Multisubunit Na H antiporter MnhC subunit
KI609_10610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KI609_10610	COG2111	Na H antiporter
KI609_10620	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KI609_10630	COG0776	regulation of translation
KI609_10640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KI609_10645	COG0287	Prephenate dehydrogenase
KI609_10650	COG0077	Prephenate dehydratase
KI609_10650	COG1605	Chorismate mutase
KI609_10655	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KI609_10670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KI609_10685	COG0582	viral genome integration into host DNA
KI609_10830	COG0745	RESPONSE REGULATOR receiver
KI609_10835	COG5002	protein histidine kinase activity
KI609_10835	COG3850	Histidine kinase
KI609_10840	COG2358	TRAP transporter, solute receptor (TAXI family
KI609_10845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KI609_10860	COG2986	histidine ammonia-lyase
KI609_10865	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KI609_10875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KI609_10880	COG0765	amino acid transport
KI609_10885	COG1126	abc transporter atp-binding protein
KI609_10900	COG1228	amidohydrolase
KI609_10920	COG0688	phosphatidylethanolamine metabolic process
KI609_10955	COG0617	tRNA 3'-terminal CCA addition
KI609_10955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KI609_10955	COG3620	sequence-specific DNA binding
KI609_10960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KI609_10975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KI609_10985	COG2917	probably involved in intracellular septation
KI609_10990	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KI609_10995	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KI609_11000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KI609_11005	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_11015	COG0559	Belongs to the binding-protein-dependent transport system permease family
KI609_11025	COG0411	ABC transporter
KI609_11035	COG4716	Myosin-crossreactive antigen
KI609_11040	COG1024	Enoyl-CoA hydratase
KI609_11040	COG1250	3-hydroxyacyl-CoA dehydrogenase
KI609_11045	COG0183	Belongs to the thiolase family
KI609_11050	COG1960	acyl-CoA dehydrogenase activity
KI609_11060	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_11070	COG2130	NADP-dependent
KI609_11075	COG2153	protein acetylation
KI609_11080	COG1960	acyl-CoA dehydrogenase activity
KI609_11095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KI609_11105	COG3459	Glycosyltransferase 36 associated
KI609_11130	COG5001	Diguanylate cyclase
KI609_11130	COG4251	negative regulation of phosphorylation
KI609_11130	COG3706	GGDEF domain
KI609_11130	COG2203	Gaf domain
KI609_11135	COG2814	Major facilitator Superfamily
KI609_11140	COG2814	Major facilitator Superfamily
KI609_11145	COG1280	lysine exporter protein (LysE YggA)
KI609_11160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KI609_11165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KI609_11200	COG2197	response regulator
KI609_11210	COG2183	response to ionizing radiation
KI609_11240	COG0657	acetylesterase activity
KI609_11255	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KI609_11260	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KI609_11265	COG0470	DNA polymerase III
KI609_11275	COG0084	hydrolase, TatD family'
KI609_11285	COG1132	(ABC) transporter
KI609_11290	COG0823	Involved in the tonB-independent uptake of proteins
KI609_11295	COG2885	chlorophyll binding
KI609_11305	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KI609_11320	COG0567	Dehydrogenase, E1 component
KI609_11325	COG0508	dehydrogenase complex catalyzes the overall conversion of
KI609_11330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KI609_11335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KI609_11345	COG0631	protein serine/threonine phosphatase activity
KI609_11350	COG1199	ATP-dependent helicase activity
KI609_11365	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KI609_11370	COG0542	response to heat
KI609_11380	COG2951	lytic endotransglycosylase activity
KI609_11385	COG2925	Exonuclease
KI609_11390	COG0626	cystathionine gamma-synthase activity
KI609_11395	COG0515	serine threonine protein kinase
KI609_11400	COG0700	Nucleoside recognition
KI609_11405	COG0217	transcriptional regulatory protein
KI609_11410	COG0484	heat shock protein binding
KI609_11430	COG3706	GGDEF domain
KI609_11440	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KI609_11450	COG1024	Enoyl-CoA hydratase
KI609_11450	COG1250	3-hydroxyacyl-CoA dehydrogenase
KI609_11460	COG0433	COG0433 Predicted ATPase
KI609_11465	COG0217	transcriptional regulatory protein
KI609_11470	COG0151	Belongs to the GarS family
KI609_11475	COG0408	coproporphyrinogen oxidase activity
KI609_11480	COG0799	negative regulation of ribosome biogenesis
KI609_11485	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KI609_11490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KI609_11500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KI609_11505	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_11510	COG2706	6-phosphogluconolactonase activity
KI609_11525	COG1132	(ABC) transporter
KI609_11550	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_11565	COG2203	Gaf domain
KI609_11565	COG3706	GGDEF domain
KI609_11565	COG4251	negative regulation of phosphorylation
KI609_11565	COG5001	Diguanylate cyclase
KI609_11570	COG2828	Protein conserved in bacteria
KI609_11590	COG1396	sequence-specific DNA binding
KI609_11590	COG3800	Transcriptional regulator
KI609_11600	COG1196	nuclear chromosome segregation
KI609_11610	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KI609_11615	COG1752	Esterase of the alpha-beta hydrolase superfamily
KI609_11620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KI609_11675	COG3243	poly(R)-hydroxyalkanoic acid synthase
KI609_11680	COG0183	Belongs to the thiolase family
KI609_11685	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_11690	COG0488	(ABC) transporter
KI609_11695	COG2890	protein-(glutamine-N5) methyltransferase activity
KI609_11700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KI609_11710	COG2171	N-acyltransferase activity
KI609_11715	COG0436	Aminotransferase
KI609_11720	COG0840	transmembrane signaling receptor activity
KI609_11725	COG2878	Part of a membrane complex involved in electron transport
KI609_11755	COG1522	sequence-specific DNA binding
KI609_11765	COG1022	Amp-dependent synthetase and ligase
KI609_11780	COG1802	Transcriptional regulator
KI609_11785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KI609_11785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KI609_11790	COG1703	isobutyryl-CoA mutase activity
KI609_11795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KI609_11800	COG4770	biotin carboxylase activity
KI609_11815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KI609_11820	COG3437	response regulator, receiver
KI609_11855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KI609_11870	COG0446	pyridine nucleotide-disulphide oxidoreductase
KI609_11885	COG0640	Transcriptional regulator
KI609_11890	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_11895	COG0534	Mate efflux family protein
KI609_11920	COG0346	lactoylglutathione lyase activity
KI609_11935	COG2032	superoxide dismutase activity
KI609_11940	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KI609_11960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KI609_11975	COG1309	transcriptional regulator
KI609_11980	COG0259	pyridoxamine-phosphate oxidase activity
KI609_11985	COG1846	Transcriptional regulator
KI609_11995	COG1566	PFAM secretion protein HlyD family protein
KI609_12000	COG2814	Major facilitator Superfamily
KI609_12015	COG0583	DNA-binding transcription factor activity
KI609_12030	COG1960	acyl-CoA dehydrogenase activity
KI609_12055	COG4999	Histidine kinase
KI609_12055	COG3850	Histidine kinase
KI609_12055	COG2205	protein histidine kinase activity
KI609_12055	COG3437	response regulator, receiver
KI609_12075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KI609_12080	COG1570	exodeoxyribonuclease VII activity
KI609_12085	COG0811	peptide transport
KI609_12090	COG0848	biopolymer transport protein
KI609_12095	COG1663	tetraacyldisaccharide 4'-kinase activity
KI609_12095	COG2835	tetraacyldisaccharide 4'-kinase activity
KI609_12100	COG2835	tetraacyldisaccharide 4'-kinase activity
KI609_12105	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KI609_12110	COG0563	adenylate kinase activity
KI609_12115	COG0252	asparaginase activity
KI609_12120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KI609_12125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KI609_12145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KI609_12165	COG0583	DNA-binding transcription factor activity
KI609_12170	COG0436	Aminotransferase
KI609_12180	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KI609_12185	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KI609_12190	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KI609_12200	COG0745	RESPONSE REGULATOR receiver
KI609_12210	COG0625	glutathione transferase activity
KI609_12220	COG1530	ribonuclease E activity
KI609_12225	COG0424	maF-like protein
KI609_12240	COG1752	Esterase of the alpha-beta hydrolase superfamily
KI609_12270	COG1477	protein flavinylation
KI609_12310	COG1136	(ABC) transporter
KI609_12310	COG0577	efflux transmembrane transporter activity
KI609_12325	COG1309	transcriptional regulator
KI609_12340	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KI609_12390	COG0697	spore germination
KI609_12420	COG1040	competence protein
KI609_12425	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KI609_12430	COG0791	NLP P60 protein
KI609_12470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KI609_12475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KI609_12475	COG2169	Transcriptional regulator
KI609_12485	COG3145	DNA-N1-methyladenine dioxygenase activity
KI609_12495	COG5001	Diguanylate cyclase
KI609_12495	COG4251	negative regulation of phosphorylation
KI609_12495	COG3706	GGDEF domain
KI609_12495	COG2203	Gaf domain
KI609_12505	COG0494	nUDIX hydrolase
KI609_12515	COG1960	acyl-CoA dehydrogenase activity
KI609_12520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KI609_12525	COG0508	dehydrogenase complex catalyzes the overall conversion of
KI609_12530	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KI609_12540	COG4566	intracellular signal transduction
KI609_12545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KI609_12560	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KI609_12565	COG0167	dihydroorotate dehydrogenase activity
KI609_12585	COG0579	oxidoreductase
KI609_12615	COG0443	Heat shock 70 kDa protein
KI609_12620	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KI609_12625	COG0316	Belongs to the HesB IscA family
KI609_12630	COG0822	iron-sulfur transferase activity
KI609_12635	COG1104	cysteine desulfurase activity
KI609_12640	COG1959	2 iron, 2 sulfur cluster binding
KI609_12645	COG0556	nucleotide-excision repair
KI609_12660	COG3384	dioxygenase
KI609_12665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KI609_12685	COG0456	acetyltransferase
KI609_12685	COG1846	Transcriptional regulator
KI609_12695	COG1739	Uncharacterized protein family UPF0029
KI609_12715	COG0154	amidase activity
KI609_12725	COG3048	D-serine ammonia-lyase activity
KI609_12735	COG4948	Mandelate Racemase Muconate Lactonizing
KI609_12755	COG3550	peptidyl-serine autophosphorylation
KI609_12790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KI609_12795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KI609_12800	COG4181	ATPase activity
KI609_12820	COG0626	cystathionine gamma-synthase activity
KI609_12825	COG2823	Periplasmic or secreted lipoprotein
KI609_12845	COG1054	Belongs to the UPF0176 family
KI609_12850	COG1741	Belongs to the pirin family
KI609_12865	COG2259	Doxx family
KI609_12870	COG1741	Belongs to the pirin family
KI609_12875	COG0583	DNA-binding transcription factor activity
KI609_12885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KI609_12890	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KI609_12900	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KI609_12905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KI609_12910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KI609_12940	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KI609_12945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KI609_12950	COG1802	Transcriptional regulator
KI609_12955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KI609_12960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KI609_12965	COG3842	ATPase activity
KI609_12975	COG1176	ABC-type spermidine putrescine transport system, permease component I
KI609_12980	COG1177	transmembrane transport
KI609_13030	COG3039	Transposase
KI609_13035	COG3039	Transposase
KI609_13055	COG0582	viral genome integration into host DNA
KI609_13065	COG0840	transmembrane signaling receptor activity
KI609_13070	COG0564	pseudouridine synthase activity
KI609_13075	COG2982	Protein involved in outer membrane biogenesis
KI609_13080	COG0587	DNA-directed DNA polymerase activity
KI609_13095	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KI609_13100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KI609_13115	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KI609_13120	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KI609_13125	COG3386	PFAM SMP-30 Gluconolaconase
KI609_13145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KI609_13150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KI609_13185	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_13200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KI609_13210	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KI609_13210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KI609_13215	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KI609_13220	COG0509	glycine decarboxylation via glycine cleavage system
KI609_13225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KI609_13225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KI609_13230	COG0545	Peptidyl-prolyl cis-trans isomerase
KI609_13255	COG0564	pseudouridine synthase activity
KI609_13260	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_13265	COG0183	Belongs to the thiolase family
KI609_13270	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_13275	COG0589	response to stress
KI609_13300	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_13310	COG1643	Atp-dependent helicase
KI609_13315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KI609_13315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KI609_13320	COG2367	Beta-lactamase
KI609_13330	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KI609_13335	COG1054	Belongs to the UPF0176 family
KI609_13350	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KI609_13355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KI609_13360	COG4208	sulfate ABC transporter
KI609_13365	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KI609_13370	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KI609_13380	COG0450	alkyl hydroperoxide reductase
KI609_13385	COG0583	DNA-binding transcription factor activity
KI609_13390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KI609_13425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KI609_13435	COG0454	-acetyltransferase
KI609_13435	COG0456	acetyltransferase
KI609_13440	COG2011	ABC-type metal ion transport system permease component
KI609_13445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KI609_13455	COG2271	Major facilitator Superfamily
KI609_13460	COG2814	Major facilitator Superfamily
KI609_13475	COG3039	Transposase
KI609_13480	COG3039	Transposase
KI609_13485	COG3039	Transposase
KI609_13490	COG3039	Transposase
KI609_13500	COG3550	peptidyl-serine autophosphorylation
KI609_13505	COG2115	Belongs to the xylose isomerase family
KI609_13510	COG1070	Carbohydrate kinase
KI609_13515	COG1940	carbohydrate kinase activity
KI609_13520	COG1129	ABC transporter
KI609_13525	COG4214	carbohydrate transport
KI609_13530	COG4213	ABC transporter substrate-binding protein
KI609_13540	COG3386	PFAM SMP-30 Gluconolaconase
KI609_13555	COG1012	belongs to the aldehyde dehydrogenase family
KI609_13560	COG1879	ABC-type sugar transport system periplasmic component
KI609_13565	COG4213	ABC transporter substrate-binding protein
KI609_13575	COG4214	carbohydrate transport
KI609_13585	COG1172	Belongs to the binding-protein-dependent transport system permease family
KI609_13590	COG1172	Belongs to the binding-protein-dependent transport system permease family
KI609_13605	COG3734	2-keto-3-deoxy-galactonokinase
KI609_13610	COG0800	Aldolase
KI609_13615	COG4948	Mandelate Racemase Muconate Lactonizing
KI609_13650	COG0642	Histidine kinase
KI609_13665	COG1116	anion transmembrane transporter activity
KI609_13670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KI609_13680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KI609_13690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KI609_13695	COG0431	NADPH-dependent FMN reductase
KI609_13700	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KI609_13705	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KI609_13715	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KI609_13715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KI609_13720	COG0730	response to heat
KI609_13740	COG0175	sulfate reduction
KI609_13745	COG2895	sulfate adenylyltransferase (ATP) activity
KI609_13750	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KI609_13755	COG0492	ferredoxin-NADP+ reductase activity
KI609_13770	COG0351	phosphomethylpyrimidine kinase
KI609_13785	COG2022	thiamine diphosphate biosynthetic process
KI609_13800	COG1250	3-hydroxyacyl-CoA dehydrogenase
KI609_13805	COG1024	Enoyl-CoA hydratase
KI609_13840	COG1619	proteins homologs of microcin C7 resistance protein MccF
KI609_13860	COG1648	precorrin-2 dehydrogenase activity
KI609_13860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KI609_13875	COG2010	Cytochrome c
KI609_13880	COG3391	amine dehydrogenase activity
KI609_13900	COG0535	radical SAM domain protein
KI609_13910	COG1845	cytochrome c oxidase, subunit III
KI609_13920	COG2010	Cytochrome c
KI609_13955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KI609_13960	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KI609_13965	COG0515	serine threonine protein kinase
KI609_13965	COG2815	serine threonine protein kinase
KI609_13970	COG2116	formate transmembrane transporter activity
KI609_13975	COG3707	response regulator
KI609_13980	COG2146	nitrite reductase [NAD(P)H] activity
KI609_13985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KI609_13995	COG3047	cAMP biosynthetic process
KI609_14000	COG2354	Protein conserved in bacteria
KI609_14005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KI609_14010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KI609_14010	COG0047	phosphoribosylformylglycinamidine synthase activity
KI609_14015	COG0024	Methionine aminopeptidase
KI609_14020	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KI609_14025	COG0242	peptide deformylase activity
KI609_14030	COG2832	Protein of unknown function (DUF454)
KI609_14060	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KI609_14065	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KI609_14070	COG1414	Transcriptional regulator
KI609_14080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KI609_14085	COG1183	phosphatidylcholine synthase activity
KI609_14090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KI609_14095	COG0440	acetolactate synthase activity
KI609_14100	COG0028	Belongs to the TPP enzyme family
KI609_14125	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KI609_14135	COG0347	Belongs to the P(II) protein family
KI609_14145	COG1492	cobalamin metabolic process
KI609_14150	COG0719	Fe-S assembly protein
KI609_14155	COG0396	ATPase activity
KI609_14165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KI609_14170	COG0822	iron-sulfur transferase activity
KI609_14175	COG2151	metal-sulfur cluster biosynthetic enzyme
KI609_14195	COG0835	chemotaxis
KI609_14210	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KI609_14255	COG1773	rubredoxin
KI609_14265	COG1012	belongs to the aldehyde dehydrogenase family
KI609_14285	COG0701	Predicted permease
KI609_14300	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KI609_14305	COG0746	molybdenum cofactor guanylyltransferase activity
KI609_14315	COG0303	'Molybdopterin
KI609_14325	COG0328	RNA-DNA hybrid ribonuclease activity
KI609_14330	COG2226	methyltransferase
KI609_14335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KI609_14340	COG0741	lytic transglycosylase activity
KI609_14340	COG1388	LysM domain
KI609_14360	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KI609_14365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KI609_14370	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KI609_14375	COG3038	cytochrome b561
KI609_14390	COG2826	transposase and inactivated derivatives, IS30 family
KI609_14450	COG0789	Transcriptional regulator
KI609_14480	COG2132	Multicopper oxidase
KI609_14485	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KI609_14500	COG3191	aminopeptidase activity
KI609_14515	COG0488	(ABC) transporter
KI609_14520	COG0513	Belongs to the DEAD box helicase family
KI609_14525	COG0702	epimerase
KI609_14555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KI609_14565	COG0776	regulation of translation
KI609_14570	COG0473	3-isopropylmalate dehydrogenase activity
KI609_14580	COG0322	excinuclease ABC activity
KI609_14595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KI609_14600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KI609_14615	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KI609_14620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KI609_14625	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
KI609_14645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KI609_14655	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_14675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KI609_14680	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KI609_14680	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KI609_14685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KI609_14700	COG0560	Phosphoserine phosphatase
KI609_14705	COG1959	2 iron, 2 sulfur cluster binding
KI609_14710	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KI609_14720	COG3530	Putative quorum-sensing-regulated virulence factor
KI609_14725	COG0023	Translation Initiation Factor
KI609_14735	COG0513	Belongs to the DEAD box helicase family
KI609_14750	COG0840	transmembrane signaling receptor activity
KI609_14755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KI609_14770	COG0446	pyridine nucleotide-disulphide oxidoreductase
KI609_14770	COG1902	pentaerythritol trinitrate reductase activity
KI609_14780	COG2900	Belongs to the SlyX family
KI609_14785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KI609_14795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KI609_14800	COG0583	DNA-binding transcription factor activity
KI609_14810	COG4829	muconolactone delta-isomerase
KI609_14825	COG0471	metal ion transport
KI609_14830	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KI609_14835	COG0778	Nitroreductase
KI609_14840	COG1492	cobalamin metabolic process
KI609_14855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KI609_14860	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KI609_14870	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KI609_14875	COG1429	ligase activity, forming nitrogen-metal bonds
KI609_14890	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KI609_14895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KI609_14915	COG4206	TonB-dependent receptor
KI609_14930	COG0730	response to heat
KI609_14940	COG2199	diguanylate cyclase activity
KI609_14940	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KI609_14955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KI609_14990	COG3278	Belongs to the heme-copper respiratory oxidase family
KI609_15000	COG2217	Heavy metal translocating P-type atpase
KI609_15035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KI609_15045	COG0583	DNA-binding transcription factor activity
KI609_15055	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_15075	COG1802	Transcriptional regulator
KI609_15090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KI609_15095	COG0129	dihydroxy-acid dehydratase activity
KI609_15100	COG0129	dihydroxy-acid dehydratase activity
KI609_15110	COG4654	Cytochrome c, class I
KI609_15120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KI609_15130	COG4175	Glycine betaine
KI609_15135	COG4176	ABC-type proline glycine betaine transport system permease component
KI609_15140	COG2113	Glycine betaine
KI609_15155	COG2205	protein histidine kinase activity
KI609_15160	COG0745	RESPONSE REGULATOR receiver
KI609_15165	COG0114	fumarate hydratase activity
KI609_15205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KI609_15210	COG1451	nucleotide metabolic process
KI609_15240	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KI609_15245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KI609_15250	COG0740	serine-type endopeptidase activity
KI609_15255	COG0544	peptidyl-prolyl cis-trans isomerase activity
KI609_15285	COG1760	l-serine dehydratase
KI609_15295	COG1562	ergosterol biosynthetic process
KI609_15300	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KI609_15320	COG1011	Hydrolase
KI609_15325	COG1609	Transcriptional regulator
KI609_15335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KI609_15345	COG1126	abc transporter atp-binding protein
KI609_15350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KI609_15355	COG0765	amino acid transport
KI609_15360	COG0765	amino acid transport
KI609_15365	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KI609_15370	COG1067	ATP-dependent peptidase activity
KI609_15380	COG2826	transposase and inactivated derivatives, IS30 family
KI609_15385	COG0765	amino acid transport
KI609_15390	COG0765	amino acid transport
KI609_15395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KI609_15405	COG0024	Methionine aminopeptidase
KI609_15410	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KI609_15445	COG2204	response regulator
KI609_15460	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_15470	COG0642	Histidine kinase
KI609_15485	COG0527	aspartate kinase activity
KI609_15490	COG0037	tRNA processing
KI609_15495	COG0825	malonyl-CoA metabolic process
KI609_15505	COG0215	cysteine-tRNA ligase activity
KI609_15530	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KI609_15535	COG3228	Belongs to the MtfA family
KI609_15555	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KI609_15560	COG1522	sequence-specific DNA binding
KI609_15575	COG3384	dioxygenase
KI609_15585	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KI609_15595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KI609_15645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KI609_15705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KI609_15715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KI609_15720	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_15725	COG1607	acyl-coa hydrolase
KI609_15785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KI609_15805	COG1309	transcriptional regulator
KI609_15810	COG0604	alcohol dehydrogenase
KI609_15815	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_15840	COG0564	pseudouridine synthase activity
KI609_15850	COG1285	pathogenesis
KI609_15900	COG1289	transmembrane transporter activity
KI609_15905	COG2918	glutathione biosynthetic process
KI609_15910	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_15935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KI609_15940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KI609_15945	COG0436	Aminotransferase
KI609_15950	COG0824	Thioesterase
KI609_15990	COG0039	L-malate dehydrogenase activity
KI609_15995	COG2188	Transcriptional regulator
KI609_16005	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KI609_16015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KI609_16020	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KI609_16025	COG0372	Belongs to the citrate synthase family
KI609_16030	COG4977	sequence-specific DNA binding
KI609_16035	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KI609_16040	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KI609_16045	COG2194	sulfuric ester hydrolase activity
KI609_16060	COG2388	GCN5-related N-acetyl-transferase
KI609_16065	COG2826	transposase and inactivated derivatives, IS30 family
KI609_16100	COG0583	DNA-binding transcription factor activity
KI609_16110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KI609_16125	COG1271	oxidase subunit
KI609_16130	COG1294	oxidase, subunit
KI609_16140	COG1960	acyl-CoA dehydrogenase activity
KI609_16155	COG1196	nuclear chromosome segregation
KI609_16155	COG3264	Mechanosensitive ion channel
KI609_16170	COG0714	Associated with various cellular activities
KI609_16185	COG2951	lytic endotransglycosylase activity
KI609_16190	COG1131	(ABC) transporter
KI609_16195	COG0842	Transport permease protein
KI609_16200	COG0534	Mate efflux family protein
KI609_16215	COG0683	leucine binding
KI609_16225	COG1136	(ABC) transporter
KI609_16225	COG0577	efflux transmembrane transporter activity
KI609_16240	COG1538	Outer membrane efflux protein
KI609_16245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KI609_16265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KI609_16270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KI609_16275	COG1116	anion transmembrane transporter activity
KI609_16280	COG0517	IMP dehydrogenase activity
KI609_16285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KI609_16290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KI609_16295	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KI609_16300	COG3265	gluconokinase activity
KI609_16305	COG1609	Transcriptional regulator
KI609_16320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KI609_16335	COG0243	molybdopterin cofactor binding
KI609_16340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KI609_16355	COG1607	acyl-coa hydrolase
KI609_16370	COG2081	HI0933 family
KI609_16375	COG0640	Transcriptional regulator
KI609_16395	COG3300	MHYT domain
KI609_16395	COG5001	Diguanylate cyclase
KI609_16400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KI609_16410	COG0583	DNA-binding transcription factor activity
KI609_16415	COG0473	3-isopropylmalate dehydrogenase activity
KI609_16425	COG0583	DNA-binding transcription factor activity
KI609_16445	COG0312	modulator of DNA gyrase
KI609_16450	COG3028	Belongs to the UPF0307 family
KI609_16455	COG0521	Mo-molybdopterin cofactor biosynthetic process
KI609_16465	COG1045	serine acetyltransferase
KI609_16475	COG0483	inositol monophosphate 1-phosphatase activity
KI609_16505	COG0840	transmembrane signaling receptor activity
KI609_16510	COG0835	chemotaxis
KI609_16560	COG2764	glyoxalase bleomycin resistance protein dioxygenase
KI609_16565	COG2826	transposase and inactivated derivatives, IS30 family
KI609_16580	COG0583	DNA-binding transcription factor activity
KI609_16615	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KI609_16655	COG1968	undecaprenyl-diphosphatase activity
KI609_16670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KI609_16675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KI609_16700	COG3275	phosphorelay sensor kinase activity
KI609_16705	COG3279	Response regulator of the LytR AlgR family
KI609_16710	COG1280	lysine exporter protein (LysE YggA)
KI609_16715	COG4133	protoheme IX ABC transporter activity
KI609_16730	COG0385	Bile acid
KI609_16735	COG2072	flavoprotein involved in K transport
KI609_16740	COG1414	Transcriptional regulator
KI609_16760	COG2205	protein histidine kinase activity
KI609_16760	COG4999	Histidine kinase
KI609_16760	COG3850	Histidine kinase
KI609_16760	COG3437	response regulator, receiver
KI609_16770	COG0784	Response regulator, receiver
KI609_16770	COG3437	response regulator, receiver
KI609_16775	COG0745	RESPONSE REGULATOR receiver
KI609_16795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KI609_16795	COG3608	succinylglutamate desuccinylase aspartoacylase
KI609_16810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KI609_16850	COG0655	NAD(P)H dehydrogenase (quinone) activity
KI609_16860	COG0798	PFAM Bile acid sodium symporter
KI609_16875	COG0640	Transcriptional regulator
KI609_16890	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KI609_16895	COG2200	EAL domain
KI609_16895	COG2202	Pas domain
KI609_16895	COG2199	diguanylate cyclase activity
KI609_16920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KI609_16935	COG1126	abc transporter atp-binding protein
KI609_16955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KI609_16960	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KI609_16965	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KI609_16970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KI609_16975	COG0142	geranyltranstransferase activity
KI609_16980	COG1722	exodeoxyribonuclease VII activity
KI609_17020	COG0628	permease
KI609_17025	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KI609_17030	COG0181	hydroxymethylbilane synthase activity
KI609_17050	COG3038	cytochrome b561
KI609_17075	COG0525	valine-tRNA ligase activity
KI609_17080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KI609_17085	COG0425	Belongs to the sulfur carrier protein TusA family
KI609_17125	COG2003	Belongs to the UPF0758 family
KI609_17155	COG0582	viral genome integration into host DNA
KI609_17170	COG0583	DNA-binding transcription factor activity
KI609_17175	COG1960	acyl-CoA dehydrogenase activity
KI609_17210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KI609_17215	COG0129	dihydroxy-acid dehydratase activity
KI609_17225	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KI609_17230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KI609_17235	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_17245	COG1090	epimerase
KI609_17250	COG0583	DNA-binding transcription factor activity
KI609_17255	COG0835	chemotaxis
KI609_17255	COG0784	Response regulator, receiver
KI609_17300	COG0617	tRNA 3'-terminal CCA addition
KI609_17310	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KI609_17320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KI609_17330	COG0840	transmembrane signaling receptor activity
KI609_17350	COG4977	sequence-specific DNA binding
KI609_17350	COG1917	Cupin 2, conserved barrel domain protein
KI609_17370	COG2912	Transglutaminase-like superfamily
KI609_17375	COG0728	peptidoglycan biosynthetic process
KI609_17380	COG0268	Binds directly to 16S ribosomal RNA
KI609_17390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KI609_17395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KI609_17415	COG0727	PFAM Uncharacterised protein family (UPF0153)
KI609_17420	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KI609_17430	COG3483	tryptophan 2,3-dioxygenase activity
KI609_17445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KI609_17460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KI609_17465	COG2916	Histone family protein nucleoid-structuring protein H-NS
KI609_17470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KI609_17475	COG1477	protein flavinylation
KI609_17490	COG4263	nitrous-oxide reductase activity
KI609_17510	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KI609_17525	COG0513	Belongs to the DEAD box helicase family
KI609_17530	COG2321	neutral zinc metallopeptidase
KI609_17545	COG0717	Belongs to the dCTP deaminase family
KI609_17550	COG0402	S-adenosylhomocysteine deaminase activity
KI609_17555	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_17560	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_17565	COG0840	transmembrane signaling receptor activity
KI609_17570	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KI609_17585	COG4603	Belongs to the binding-protein-dependent transport system permease family
KI609_17590	COG3845	ABC transporter
KI609_17605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KI609_17610	COG3447	MASE1 domain protein
KI609_17610	COG5002	protein histidine kinase activity
KI609_17610	COG5001	Diguanylate cyclase
KI609_17630	COG3300	MHYT domain
KI609_17630	COG5001	Diguanylate cyclase
KI609_17655	COG2186	Transcriptional regulator
KI609_17670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KI609_17680	COG0280	phosphate acetyltransferase
KI609_17680	COG0281	malic enzyme
KI609_17690	COG1116	anion transmembrane transporter activity
KI609_17695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KI609_17700	COG0829	nickel cation binding
KI609_17710	COG0436	Aminotransferase
KI609_17720	COG2814	Major facilitator Superfamily
KI609_17735	COG1597	lipid kinase activity
KI609_17770	COG2203	Gaf domain
KI609_17770	COG4251	negative regulation of phosphorylation
KI609_17770	COG5001	Diguanylate cyclase
KI609_17770	COG3706	GGDEF domain
KI609_17815	COG0831	urea catabolic process
KI609_17825	COG0832	Belongs to the urease beta subunit family
KI609_17830	COG0804	urea catabolic process
KI609_17840	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KI609_17845	COG0830	nickel cation binding
KI609_17850	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KI609_17885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KI609_17890	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KI609_17910	COG1561	YicC-like family, N-terminal region
KI609_17915	COG0194	GDP metabolic process
KI609_17920	COG1758	RNA polymerase activity
KI609_17925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KI609_17945	COG1420	regulation of RNA biosynthetic process
KI609_17950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KI609_17955	COG0497	DNA recombination
KI609_17960	COG1660	Displays ATPase and GTPase activities
KI609_17965	COG1194	a g-specific adenine glycosylase
KI609_17975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KI609_17985	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KI609_17990	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KI609_18000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KI609_18005	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KI609_18010	COG0193	aminoacyl-tRNA hydrolase activity
KI609_18015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KI609_18025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KI609_18030	COG0444	Belongs to the ABC transporter superfamily
KI609_18035	COG4608	Belongs to the ABC transporter superfamily
KI609_18045	COG0154	amidase activity
KI609_18060	COG3039	Transposase
KI609_18070	COG0588	phosphoglycerate mutase activity
KI609_18095	COG0302	gtp cyclohydrolase
KI609_18100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KI609_18110	COG0745	RESPONSE REGULATOR receiver
KI609_18125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KI609_18150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KI609_18165	COG2226	methyltransferase
KI609_18185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KI609_18195	COG1175	transmembrane transport
KI609_18200	COG0395	ABC-type sugar transport system, permease component
KI609_18205	COG3842	ATPase activity
KI609_18215	COG0584	glycerophosphoryl diester phosphodiesterase
KI609_18220	COG1511	domain protein
KI609_18220	COG3264	Mechanosensitive ion channel
KI609_18230	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KI609_18235	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KI609_18245	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KI609_18250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KI609_18255	COG1253	flavin adenine dinucleotide binding
KI609_18260	COG0741	lytic transglycosylase activity
KI609_18265	COG0442	prolyl-tRNA aminoacylation
KI609_18270	COG0494	nUDIX hydrolase
KI609_18275	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KI609_18280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KI609_18285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KI609_18290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KI609_18295	COG0142	geranyltranstransferase activity
KI609_18320	COG0237	dephospho-CoA kinase activity
KI609_18325	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KI609_18330	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KI609_18335	COG0494	nUDIX hydrolase
KI609_18345	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KI609_18350	COG0653	protein targeting
KI609_18355	COG0739	heme binding
KI609_18370	COG2969	positive regulation of protein catabolic process
KI609_18375	COG0625	glutathione transferase activity
KI609_18380	COG2857	Cytochrome c1
KI609_18385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KI609_18390	COG0723	plastoquinol--plastocyanin reductase activity
KI609_18395	COG1970	mechanosensitive ion channel activity
KI609_18400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KI609_18405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KI609_18410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KI609_18415	COG0805	protein transport
KI609_18420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KI609_18425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KI609_18430	COG0537	adenosine 5'-monophosphoramidase activity
KI609_18445	COG0140	phosphoribosyl-ATP diphosphatase activity
KI609_18450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KI609_18455	COG0107	imidazoleglycerol-phosphate synthase activity
KI609_18460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KI609_18485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KI609_18495	COG0131	Imidazoleglycerol-phosphate dehydratase
KI609_18500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KI609_18515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KI609_18535	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KI609_18540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KI609_18545	COG5007	Belongs to the BolA IbaG family
KI609_18550	COG0842	Transport permease protein
KI609_18555	COG1131	(ABC) transporter
KI609_18570	COG2853	Lipoprotein
KI609_18575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KI609_18580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KI609_18585	COG1127	ABC transporter
KI609_18595	COG0067	glutamate synthase
KI609_18595	COG0069	glutamate synthase activity
KI609_18595	COG0070	glutamate synthase
KI609_18615	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KI609_18620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KI609_18660	COG1965	Belongs to the frataxin family
KI609_18675	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KI609_18680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KI609_18685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KI609_18690	COG1333	cytochrome c biogenesis protein
KI609_18710	COG1560	Kdo2-lipid A biosynthetic process
KI609_18720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KI609_18740	COG1051	belongs to the nudix hydrolase family
KI609_18740	COG1056	cytidyltransferase-related domain
KI609_18750	COG0459	protein refolding
KI609_18755	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KI609_18765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KI609_18800	COG1132	(ABC) transporter
KI609_18805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KI609_18805	COG1181	Belongs to the D-alanine--D-alanine ligase family
KI609_18810	COG0189	ligase activity
KI609_18810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KI609_18815	COG3045	CreA protein
KI609_18830	COG0575	Belongs to the CDS family
KI609_18835	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KI609_18840	COG3781	membrane
KI609_18845	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KI609_18855	COG2079	MmgE PrpD family protein
KI609_18870	COG0183	Belongs to the thiolase family
KI609_18875	COG1024	Enoyl-CoA hydratase
KI609_18875	COG1250	3-hydroxyacyl-CoA dehydrogenase
KI609_18885	COG1024	Enoyl-CoA hydratase
KI609_18900	COG2205	protein histidine kinase activity
KI609_18905	COG0745	RESPONSE REGULATOR receiver
KI609_18915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KI609_18935	COG0662	Cupin 2, conserved barrel domain protein
KI609_18950	COG3135	benzoate transporter
KI609_19070	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_19080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KI609_19080	COG0546	phosphoglycolate phosphatase activity
KI609_19135	COG2267	carboxylic ester hydrolase activity
KI609_19145	COG3180	Ammonia monooxygenase
KI609_19150	COG2079	MmgE PrpD family protein
KI609_19155	COG1960	acyl-CoA dehydrogenase activity
KI609_19175	COG1024	Enoyl-CoA hydratase
KI609_19175	COG1250	3-hydroxyacyl-CoA dehydrogenase
KI609_19180	COG0183	Belongs to the thiolase family
KI609_19315	COG3039	Transposase
KI609_19325	COG0789	Transcriptional regulator
KI609_19410	COG1074	ATP-dependent DNA helicase activity
KI609_19415	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KI609_19425	COG1522	sequence-specific DNA binding
KI609_19440	COG3706	GGDEF domain
KI609_19445	COG2205	protein histidine kinase activity
KI609_19450	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KI609_19465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KI609_19485	COG0583	DNA-binding transcription factor activity
KI609_19490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KI609_19495	COG0739	heme binding
KI609_19500	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KI609_19505	COG2814	Major facilitator Superfamily
KI609_19510	COG0316	Belongs to the HesB IscA family
KI609_19525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KI609_19530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KI609_19540	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KI609_19545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KI609_19550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KI609_19560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KI609_19565	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KI609_19585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KI609_19600	COG4154	Belongs to the RbsD FucU family
KI609_19635	COG1522	sequence-specific DNA binding
KI609_19650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KI609_19655	COG0683	leucine binding
KI609_19665	COG0477	Major facilitator Superfamily
KI609_19695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KI609_19710	COG1024	Enoyl-CoA hydratase
KI609_19715	COG2318	DinB family
KI609_19720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KI609_19725	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_19750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KI609_19755	COG3012	SEC-C Motif Domain Protein
KI609_19775	COG1960	acyl-CoA dehydrogenase activity
KI609_19780	COG0300	oxidoreductase activity
KI609_19795	COG0183	Belongs to the thiolase family
KI609_19800	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KI609_19805	COG0288	reversible hydration of carbon dioxide
KI609_19810	COG1960	acyl-CoA dehydrogenase activity
KI609_19820	COG0789	Transcriptional regulator
KI609_19850	COG0488	(ABC) transporter
KI609_19855	COG2201	protein-glutamate methylesterase activity
KI609_19860	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KI609_19865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KI609_19870	COG0835	chemotaxis
KI609_19875	COG0643	Histidine kinase
KI609_19875	COG2198	Histidine kinase
KI609_19880	COG2201	protein-glutamate methylesterase activity
KI609_19895	COG2197	response regulator
KI609_19905	COG1987	bacterial-type flagellum assembly
KI609_19920	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KI609_19965	COG1677	Flagellar hook-basal body complex protein FliE
KI609_19975	COG1516	flagellar protein fliS
KI609_19995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KI609_20000	COG1360	Flagellar Motor Protein
KI609_20005	COG0745	RESPONSE REGULATOR receiver
KI609_20010	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KI609_20020	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KI609_20050	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KI609_20055	COG1815	bacterial-type flagellum-dependent cell motility
KI609_20060	COG1558	bacterial-type flagellum-dependent cell motility
KI609_20065	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KI609_20075	COG4787	bacterial-type flagellum-dependent cell motility
KI609_20090	COG1706	bacterial-type flagellum-dependent cell motility
KI609_20105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KI609_20115	COG0436	Aminotransferase
KI609_20135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KI609_20140	COG0625	glutathione transferase activity
KI609_20150	COG0384	phenazine biosynthesis protein PhzF
KI609_20160	COG1280	lysine exporter protein (LysE YggA)
KI609_20175	COG1715	Restriction endonuclease
KI609_20190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KI609_20200	COG4232	protein-disulfide reductase activity
KI609_20205	COG1832	CoA-binding protein
KI609_20210	COG2814	Major facilitator Superfamily
KI609_20215	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KI609_20220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KI609_20225	COG3174	membrane
KI609_20230	COG0405	Gamma-glutamyltransferase
KI609_20250	COG0679	Auxin Efflux Carrier
KI609_20260	COG0210	DNA helicase
KI609_20285	COG0343	queuine tRNA-ribosyltransferase activity
KI609_20320	COG3268	Saccharopine dehydrogenase
KI609_20335	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KI609_20340	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_20345	COG0204	Acyl-transferase
KI609_20345	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_20375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KI609_20385	COG0583	DNA-binding transcription factor activity
KI609_20390	COG1253	flavin adenine dinucleotide binding
KI609_20405	COG2847	Copper chaperone PCu(A)C
KI609_20420	COG0625	glutathione transferase activity
KI609_20440	COG2095	MarC family integral membrane protein
KI609_20450	COG0583	DNA-binding transcription factor activity
KI609_20460	COG0203	ribosomal protein L17
KI609_20465	COG0202	RNA polymerase activity
KI609_20470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KI609_20475	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KI609_20480	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KI609_20485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KI609_20490	COG0201	protein transport
KI609_20495	COG0200	Binds to the 23S rRNA
KI609_20500	COG1841	ribosomal large subunit assembly
KI609_20505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KI609_20510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KI609_20515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KI609_20520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KI609_20525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KI609_20530	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KI609_20535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KI609_20540	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KI609_20545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KI609_20560	COG0395	ABC-type sugar transport system, permease component
KI609_20575	COG3842	ATPase activity
KI609_20585	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KI609_20595	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KI609_20605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KI609_20615	COG5002	protein histidine kinase activity
KI609_20625	COG0783	Belongs to the Dps family
KI609_20630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KI609_20645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KI609_20660	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KI609_20680	COG0583	DNA-binding transcription factor activity
KI609_20685	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KI609_20690	COG0134	indole-3-glycerol-phosphate synthase activity
KI609_20700	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KI609_20705	COG1280	lysine exporter protein (LysE YggA)
KI609_20710	COG0512	Glutamine amidotransferase of anthranilate synthase
KI609_20730	COG0840	transmembrane signaling receptor activity
KI609_20735	COG0546	phosphoglycolate phosphatase activity
KI609_20765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KI609_20770	COG2967	ApaG domain
KI609_20785	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
KI609_20795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KI609_20805	COG3243	poly(R)-hydroxyalkanoic acid synthase
KI609_20820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KI609_20825	COG1129	ABC transporter
KI609_20825	COG0842	Transport permease protein
KI609_20830	COG0842	Transport permease protein
KI609_20840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KI609_20845	COG0589	response to stress
KI609_20855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KI609_20860	COG1546	Belongs to the CinA family
KI609_20865	COG0596	Alpha beta hydrolase
KI609_20895	COG0659	secondary active sulfate transmembrane transporter activity
KI609_20900	COG0653	protein targeting
KI609_20905	COG0069	glutamate synthase activity
KI609_20915	COG4178	(ABC) transporter
KI609_20935	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KI609_20940	COG1137	ATPase activity
KI609_20950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KI609_20960	COG0018	arginyl-trna synthetase
KI609_20975	COG1301	dicarboxylic acid transport
KI609_20980	COG4191	Histidine kinase
KI609_20995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KI609_21000	COG0840	transmembrane signaling receptor activity
KI609_21010	COG1942	4-Oxalocrotonate Tautomerase
KI609_21015	COG2814	Major facilitator Superfamily
KI609_21020	COG0121	glutamine amidotransferase
KI609_21075	COG0189	ligase activity
KI609_21080	COG3135	benzoate transporter
KI609_21085	COG3158	transport of potassium into the cell
KI609_21095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KI609_21100	COG0569	domain protein
KI609_21105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KI609_21130	COG3039	Transposase
KI609_21140	COG0495	leucyl-tRNA aminoacylation
KI609_21155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KI609_21160	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KI609_21165	COG0735	belongs to the Fur family
KI609_21170	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KI609_21180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KI609_21185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KI609_21195	COG3118	belongs to the thioredoxin family
KI609_21200	COG0693	protein deglycase activity
KI609_21215	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KI609_21220	COG0009	L-threonylcarbamoyladenylate synthase
KI609_21230	COG3047	cAMP biosynthetic process
KI609_21250	COG2027	D-alanyl-D-alanine carboxypeptidase
KI609_21255	COG0840	transmembrane signaling receptor activity
KI609_21265	COG1214	PFAM Peptidase M22, glycoprotease
KI609_21285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KI609_21290	COG0747	negative chemotaxis
KI609_21295	COG4608	Belongs to the ABC transporter superfamily
KI609_21300	COG0444	Belongs to the ABC transporter superfamily
KI609_21305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KI609_21310	COG0601	transmembrane transport
KI609_21315	COG0318	PFAM AMP-dependent synthetase and ligase
KI609_21320	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KI609_21325	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KI609_21355	COG0671	phosphoesterase, PA-phosphatase related
KI609_21370	COG0006	proline dipeptidase activity
KI609_21375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KI609_21380	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KI609_21385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KI609_21390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KI609_21395	COG0668	transmembrane transport
KI609_21410	COG0667	Aldo Keto reductase
KI609_21430	COG0740	serine-type endopeptidase activity
KI609_21465	COG2159	amidohydrolase
KI609_21475	COG0583	DNA-binding transcription factor activity
KI609_21525	COG0671	phosphoesterase, PA-phosphatase related
KI609_21530	COG0463	Glycosyl transferase, family 2
KI609_21535	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KI609_21550	COG3385	transposase activity
KI609_21560	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KI609_21570	COG1309	transcriptional regulator
KI609_21575	COG4221	oxidoreductase activity
KI609_21580	COG0183	Belongs to the thiolase family
KI609_21585	COG1047	Peptidyl-prolyl cis-trans
KI609_21590	COG0589	response to stress
KI609_21625	COG0840	transmembrane signaling receptor activity
KI609_21630	COG2378	regulation of single-species biofilm formation
KI609_21650	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_21655	COG0583	DNA-binding transcription factor activity
KI609_21660	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_21695	COG3148	PFAM DTW domain containing protein
KI609_21710	COG0747	negative chemotaxis
KI609_21715	COG0601	transmembrane transport
KI609_21730	COG4608	Belongs to the ABC transporter superfamily
KI609_21740	COG2195	Cleaves the N-terminal amino acid of tripeptides
KI609_21745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KI609_21750	COG4804	nuclease activity
KI609_21755	COG0420	3'-5' exonuclease activity
KI609_21760	COG0419	ATPase involved in DNA repair
KI609_21765	COG3039	Transposase
KI609_21780	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_21785	COG3181	Tripartite tricarboxylate transporter family receptor
KI609_21790	COG2365	Tyrosine phosphatase family
KI609_21805	COG0584	glycerophosphoryl diester phosphodiesterase
KI609_21820	COG0551	DNA topoisomerase type I activity
KI609_21820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KI609_21840	COG0642	Histidine kinase
KI609_21865	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KI609_21865	COG2066	Belongs to the glutaminase family
KI609_21870	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KI609_21885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KI609_21890	COG2137	regulation of response to DNA damage stimulus
KI609_21900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KI609_21905	COG0045	succinate-CoA ligase (ADP-forming) activity
KI609_21910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KI609_21915	COG0861	Integral membrane protein TerC family
KI609_21920	COG0515	serine threonine protein kinase
KI609_21920	COG2815	serine threonine protein kinase
KI609_21930	COG1716	ATPase activity
KI609_21940	COG1234	tRNA 3'-trailer cleavage
KI609_21950	COG3307	-O-antigen
KI609_21955	COG0315	cyclic pyranopterin monophosphate synthase activity
KI609_21965	COG4783	chaperone-mediated protein folding
KI609_21970	COG1950	PFAM Membrane protein of
KI609_21980	COG0861	Integral membrane protein TerC family
KI609_22010	COG0625	glutathione transferase activity
KI609_22015	COG1309	transcriptional regulator
KI609_22020	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KI609_22025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KI609_22030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KI609_22035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KI609_22045	COG1082	Xylose isomerase domain protein TIM barrel
KI609_22045	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KI609_22065	COG2211	Major facilitator Superfamily
KI609_22075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KI609_22105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KI609_22120	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KI609_22145	COG2885	chlorophyll binding
KI609_22185	COG3039	Transposase
KI609_22205	COG3284	Transcriptional regulator
KI609_22210	COG1012	belongs to the aldehyde dehydrogenase family
KI609_22215	COG1454	alcohol dehydrogenase
KI609_22225	COG0840	transmembrane signaling receptor activity
KI609_22250	COG0583	DNA-binding transcription factor activity
KI609_22255	COG0284	orotidine-5'-phosphate decarboxylase activity
KI609_22270	COG0126	phosphoglycerate kinase activity
KI609_22285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KI609_22295	COG0242	peptide deformylase activity
KI609_22305	COG0758	DNA mediated transformation
KI609_22315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KI609_22320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KI609_22325	COG1862	Preprotein translocase
KI609_22335	COG1522	sequence-specific DNA binding
KI609_22340	COG2814	Major facilitator Superfamily
KI609_22355	COG2814	Major facilitator Superfamily
KI609_22360	COG0629	single-stranded DNA binding
KI609_22365	COG1620	l-lactate permease
KI609_22370	COG0482	sulfurtransferase activity
KI609_22375	COG0583	DNA-binding transcription factor activity
KI609_22380	COG2828	Protein conserved in bacteria
KI609_22390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KI609_22395	COG1028	Short-chain dehydrogenase reductase Sdr
KI609_22450	COG0307	riboflavin synthase, alpha
KI609_22475	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KI609_22500	COG4786	Flagellar basal body rod
KI609_22545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KI609_22550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KI609_22555	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KI609_22565	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KI609_22590	COG1538	Outer membrane efflux protein
KI609_22600	COG1136	(ABC) transporter
KI609_22610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KI609_22615	COG1309	transcriptional regulator
KI609_22630	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KI609_22645	COG3154	lipid carrier protein
KI609_22650	COG1272	protein, Hemolysin III
KI609_22655	COG0826	peptidase U32
KI609_22660	COG0826	peptidase U32
KI609_22675	COG2267	carboxylic ester hydrolase activity
KI609_22690	COG0840	transmembrane signaling receptor activity
KI609_22695	COG3622	Belongs to the hyi family
KI609_22700	COG3039	Transposase
KI609_22710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KI609_22710	COG2813	Specifically methylates the guanine in position
KI609_22715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KI609_22720	COG2119	membrane
KI609_22725	COG0724	RNA recognition motif
KI609_22730	COG0724	RNA recognition motif
KI609_22745	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KI609_22765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KI609_22780	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KI609_22785	COG0706	membrane insertase activity
KI609_22790	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KI609_22795	COG0594	ribonuclease P activity
KI609_22800	COG0230	Belongs to the bacterial ribosomal protein bL34 family