locus-tag	class	description
HUK68_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HUK68_00010	ENOG4105VG0	50S ribosomal protein l34
HUK68_00020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HUK68_00025	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HUK68_00030	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HUK68_00045	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HUK68_00050	ENOG4105CXK	mandelate racemase muconate lactonizing
HUK68_00070	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HUK68_00075	ENOG4105C2X	Arabinose 5-phosphate isomerase
HUK68_00080	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HUK68_00090	ENOG4107FW0	short-chain dehydrogenase reductase
HUK68_00095	ENOG4105VFU	Rna-binding protein
HUK68_00105	ENOG4105VFU	Rna-binding protein
HUK68_00115	ENOG4105DWV	Homoserine O-trans-acetylase
HUK68_00130	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HUK68_00135	ENOG4105EHM	Aminoglycoside phosphotransferase
HUK68_00140	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HUK68_00145	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HUK68_00150	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HUK68_00165	ENOG4105C6K	Malic enzyme
HUK68_00195	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HUK68_00225	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
HUK68_00270	ENOG4108UUM	single-stranded DNA-binding protein
HUK68_00275	ENOG4107RDB	Major Facilitator
HUK68_00280	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HUK68_00285	ENOG4105FC8	fad dependent oxidoreductase
HUK68_00290	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HUK68_00305	ENOG4105EQ2	LysR family Transcriptional regulator
HUK68_00310	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HUK68_00315	ENOG4105BZA	Phosphoglycerate kinase
HUK68_00330	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HUK68_00340	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HUK68_00355	ENOG4105C79	DNA protecting protein DprA
HUK68_00365	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HUK68_00370	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HUK68_00375	ENOG4105VIE	preprotein translocase, subunit YajC
HUK68_00385	ENOG4105F7P	transcriptional regulator AsnC family
HUK68_00390	ENOG4107SFI	Major Facilitator superfamily
HUK68_00400	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HUK68_00410	ENOG4108ZG0	Ompa motb domain protein
HUK68_00415	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HUK68_00420	ENOG4105BZU	Histidine kinase
HUK68_00435	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HUK68_00440	ENOG4108U78	Glutathione S-transferase
HUK68_00445	ENOG4107QTF	adenylosuccinate lyase
HUK68_00450	ENOG4108VWS	Yaeq family
HUK68_00465	ENOG4108ZCF	integral membrane protein
HUK68_00475	ENOG41086DT	Membrane protein of unknown function
HUK68_00480	ENOG4105ERG	peptidase m48, ste24p
HUK68_00485	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HUK68_00490	ENOG4105KHS	type IV fimbrial pilin protein
HUK68_00495	ENOG4105YWY	
HUK68_00500	ENOG4108ZUW	Major pilin subunit
HUK68_00510	ENOG4108ZF3	Phosphatase
HUK68_00515	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HUK68_00520	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HUK68_00525	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HUK68_00530	ENOG4108004	Modulates RecA activity (By similarity)
HUK68_00535	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HUK68_00550	ENOG4105DHQ	Histidine kinase
HUK68_00575	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HUK68_00585	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HUK68_00590	ENOG4105M2Z	protein tyrosine serine phosphatase
HUK68_00595	ENOG4105CK7	Sodium proline symporter
HUK68_00600	ENOG4105BZ4	penicillin-binding protein
HUK68_00615	ENOG4106IUH	DTW domain containing protein
HUK68_00630	ENOG4105EXC	Acyl-transferase
HUK68_00640	ENOG4108Z9W	Outer membrane porin
HUK68_00655	ENOG4105CYM	Glutathione S-transferase
HUK68_00660	ENOG4105EUB	pirin domain protein
HUK68_00665	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HUK68_00680	ENOG4105EUB	pirin domain protein
HUK68_00700	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HUK68_00705	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HUK68_00710	ENOG4108S0S	Nucleotidyl transferase
HUK68_00715	ENOG4107RAQ	aminopeptidase
HUK68_00725	ENOG4105CA9	Pyruvate kinase
HUK68_00730	ENOG4105D2N	Aldolase
HUK68_00740	ENOG4105CEY	Amp-dependent synthetase and ligase
HUK68_00745	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HUK68_00750	ENOG4107QUT	magnesium and cobalt transport protein CorA
HUK68_00760	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HUK68_00765	ENOG41072GX	Peptidase M22 Glycoprotease
HUK68_00785	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HUK68_00790	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HUK68_00795	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HUK68_00800	ENOG4105K63	Thioredoxin
HUK68_00805	ENOG4105C8V	SAICAR synthetase
HUK68_00810	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HUK68_00815	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HUK68_00820	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HUK68_00825	ENOG41090R7	Ferric uptake
HUK68_00830	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HUK68_00835	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HUK68_00845	ENOG4105SG9	biopolymer transport protein, ExbD
HUK68_00850	ENOG4105CUY	Mechanosensitive ion channel
HUK68_00855	ENOG4105C8T	Leucyl-tRNA synthetase
HUK68_00875	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HUK68_00880	ENOG4105C1A	potassium transporter peripheral membrane
HUK68_00885	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HUK68_00895	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HUK68_00900	ENOG4105DKK	Benzoate
HUK68_00905	ENOG4105D7Z	glutathione synthase
HUK68_00960	ENOG4105E7A	Glutamine amidotransferase
HUK68_00965	ENOG41084KP	4-oxalocrotonate tautomerase
HUK68_00975	ENOG4107QP3	malate synthase g
HUK68_00980	ENOG4105CC0	LysR family Transcriptional regulator
HUK68_00990	ENOG4105C75	arginyL-tRNA synthetase
HUK68_01005	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HUK68_01010	ENOG4108IUZ	ABC transporter
HUK68_01015	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HUK68_01020	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HUK68_01030	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HUK68_01035	ENOG4105CHH	sulfate transporter
HUK68_01040	ENOG4107TH8	cina domain protein
HUK68_01045	ENOG4108ZAI	phosphatidylglycerophosphatase a
HUK68_01050	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HUK68_01055	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
HUK68_01070	ENOG4105NWN	ApaG protein
HUK68_01075	ENOG4105DJV	ribulose-phosphate 3-epimerase
HUK68_01080	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HUK68_01095	ENOG4105DDQ	anthranilate synthase
HUK68_01100	ENOG4107QYG	anthranilate phosphoribosyltransferase
HUK68_01105	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HUK68_01110	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HUK68_01125	ENOG4105DHS	permease protein
HUK68_01130	ENOG4105CM4	permease protein
HUK68_01135	ENOG4108IPW	abc transporter atp-binding protein
HUK68_01140	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HUK68_01145	ENOG4105CPI	Metal Dependent Phosphohydrolase
HUK68_01150	ENOG4105CB5	ATP-dependent DNA helicase recG
HUK68_01155	ENOG4105C5Q	Transcriptional regulator
HUK68_01160	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HUK68_01165	ENOG4105II7	pyrroline-5-carboxylate reductase
HUK68_01170	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HUK68_01175	ENOG4105E98	transcriptional regulator DeoR family
HUK68_01180	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HUK68_01185	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HUK68_01190	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HUK68_01195	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUK68_01200	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HUK68_01205	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HUK68_01210	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HUK68_01215	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HUK68_01220	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HUK68_01225	ENOG4105VPB	50S ribosomal protein L30
HUK68_01230	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HUK68_01235	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HUK68_01245	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUK68_01250	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HUK68_01255	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HUK68_01260	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HUK68_01265	ENOG4108ZT0	50S ribosomal protein l17
HUK68_01275	ENOG4105R8A	Heat shock protein
HUK68_01280	ENOG4105E6M	Sulphatase-modifying factor protein
HUK68_01285	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HUK68_01290	ENOG41082RQ	UPF0102 protein
HUK68_01295	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HUK68_01300	ENOG4105W4M	Transport-associated protein
HUK68_01305	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HUK68_01310	ENOG4105CZX	twitching motility protein
HUK68_01315	ENOG4105IJJ	transcriptional regulator, crp fnr family
HUK68_01320	ENOG4105CZX	twitching motility protein
HUK68_01325	ENOG4105DFA	alanine racemase domain protein
HUK68_01340	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HUK68_01345	ENOG4108JUA	Transcriptional regulator
HUK68_01350	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HUK68_01365	ENOG4106BRA	Membrane
HUK68_01370	ENOG4105D05	Receptor
HUK68_01385	ENOG4105CEP	NADH dehydrogenase
HUK68_01395	ENOG4105WH1	Two component transcriptional regulator luxr family
HUK68_01405	ENOG4105CQB	FAD linked oxidase domain protein
HUK68_01415	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HUK68_01420	ENOG4105CTX	dehydratase
HUK68_01435	ENOG4105CQB	FAD linked oxidase domain protein
HUK68_01440	ENOG4108PZW	LysR family Transcriptional regulator
HUK68_01450	ENOG4105BZU	Histidine kinase
HUK68_01485	ENOG4108I6A	alcohol dehydrogenase
HUK68_01490	ENOG4108J2R	molybdopterin oxidoreductase
HUK68_01495	ENOG4105CH2	amidohydrolase
HUK68_01520	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HUK68_01535	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HUK68_01545	ENOG4105DZS	Phenylacetate-CoA ligase
HUK68_01550	ENOG4108IV0	ABC, transporter
HUK68_01565	ENOG4105C32	Amino acid ABC transporter (Permease)
HUK68_01570	ENOG4105C0Z	ABC transporter
HUK68_01575	ENOG4108IQE	Amp-dependent synthetase and ligase
HUK68_01580	ENOG4105IJJ	transcriptional regulator, crp fnr family
HUK68_01585	ENOG4105FE9	pseudouridine synthase
HUK68_01590	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HUK68_01600	ENOG4105E27	serine threonine protein kinase
HUK68_01610	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HUK68_01615	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_01625	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HUK68_01635	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HUK68_01640	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HUK68_01645	ENOG4105FYV	Amp nucleosidase
HUK68_01650	ENOG4105BZU	Histidine kinase
HUK68_01655	ENOG4105C1J	atp-dependent rna helicase
HUK68_01665	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HUK68_01670	ENOG4105EJ9	Membrane
HUK68_01675	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HUK68_01680	ENOG4105C9A	Phoh family
HUK68_01685	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HUK68_01690	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HUK68_01700	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HUK68_01710	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HUK68_01720	ENOG4105EE5	Membrane protein terC
HUK68_01750	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HUK68_01780	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HUK68_01820	ENOG4105C26	Dehydrogenase
HUK68_01825	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HUK68_01830	ENOG4105C0A	alcohol dehydrogenase
HUK68_01840	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HUK68_01845	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HUK68_01850	ENOG4107SC1	transglycosylase
HUK68_01860	ENOG4105CEY	Amp-dependent synthetase and ligase
HUK68_01870	ENOG4105MIR	Phenylalanine 4-monooxygenase
HUK68_01890	ENOG4108JU5	Magnesium and cobalt efflux protein
HUK68_01895	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HUK68_01900	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HUK68_01925	ENOG4107EF8	Glycosyl transferase (Group 1
HUK68_01945	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HUK68_01965	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HUK68_01970	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HUK68_01975	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HUK68_01980	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HUK68_01995	ENOG4109066	lysm domain bon superfamily protein
HUK68_02000	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HUK68_02010	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HUK68_02020	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HUK68_02035	ENOG4105CAS	nag kinase
HUK68_02040	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HUK68_02045	ENOG4105DHQ	Histidine kinase
HUK68_02050	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HUK68_02065	ENOG4105CSU	acyl-Coa dehydrogenase
HUK68_02080	ENOG4105CHU	acetyl-coa acetyltransferase
HUK68_02090	ENOG4105E39	Enoyl-CoA hydratase
HUK68_02100	ENOG4105NAU	thioesterase Superfamily protein
HUK68_02105	ENOG4108JJ7	ABC transporter
HUK68_02110	ENOG4105C5I	Dehydrogenase
HUK68_02115	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HUK68_02120	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HUK68_02125	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
HUK68_02130	ENOG4107YNJ	LysR family Transcriptional regulator
HUK68_02135	ENOG4107RP9	extracellular solute-binding protein, family 3
HUK68_02140	ENOG4105EAD	ABC transporter
HUK68_02145	ENOG4105DRP	amino acid AbC transporter
HUK68_02150	ENOG4105CDA	abc transporter atp-binding protein
HUK68_02155	ENOG4105EKE	dihydroorotase
HUK68_02165	ENOG4105D0M	Protease HtpX homolog
HUK68_02170	ENOG4105EX9	Membrane
HUK68_02175	ENOG4105DZ0	fad dependent oxidoreductase
HUK68_02185	ENOG4105BZ1	(ABC) transporter
HUK68_02205	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HUK68_02220	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HUK68_02230	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HUK68_02235	ENOG4105CKI	cobalamin synthesis protein
HUK68_02250	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HUK68_02255	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HUK68_02265	ENOG4108V6E	Cell division protein mraZ
HUK68_02270	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HUK68_02285	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HUK68_02290	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HUK68_02295	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HUK68_02300	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HUK68_02305	ENOG4105CNI	cell division protein FtsW
HUK68_02310	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HUK68_02315	ENOG4105DFU	Cell wall formation (By similarity)
HUK68_02320	ENOG4105CPF	Cell wall formation (By similarity)
HUK68_02325	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HUK68_02330	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HUK68_02335	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HUK68_02340	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HUK68_02360	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HUK68_02370	ENOG4105E2X	shikimate dehydrogenase
HUK68_02385	ENOG4105IPS	esterase
HUK68_02390	ENOG4105CNI	cell division protein FtsW
HUK68_02395	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HUK68_02400	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HUK68_02405	ENOG4105WP7	tRNA pseudouridine synthase C
HUK68_02415	ENOG4105DFU	Cell wall formation (By similarity)
HUK68_02425	ENOG4107QX9	Thiol disulfide interChange protein
HUK68_02430	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HUK68_02435	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HUK68_02440	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HUK68_02450	ENOG4107T4Z	adenosine kinase
HUK68_02465	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HUK68_02470	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HUK68_02480	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HUK68_02485	ENOG4107TUY	Histidine kinase
HUK68_02500	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUK68_02510	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HUK68_02520	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HUK68_02525	ENOG4105F4R	Transcriptional regulator mode
HUK68_02530	ENOG4107RGD	Major Facilitator superfamily
HUK68_02535	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HUK68_02560	ENOG4105MRR	Transcriptional regulator (By similarity)
HUK68_02570	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HUK68_02575	ENOG4108JQ6	ABC transporter
HUK68_02580	ENOG4105BZU	Histidine kinase
HUK68_02585	ENOG4105BZU	Histidine kinase
HUK68_02640	ENOG4105E39	Enoyl-CoA hydratase
HUK68_02655	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HUK68_02670	ENOG4105C3G	gtp-binding protein
HUK68_02715	ENOG4108VSE	mercuric transport protein
HUK68_02765	ENOG4105W1Y	Transcriptional regulator
HUK68_02855	ENOG4105DIJ	Phosphoethanolamine transferase
HUK68_02935	ENOG4105VS8	Flagellar biosynthetic protein fliq
HUK68_02965	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HUK68_02970	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HUK68_02980	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
HUK68_03005	ENOG4105DIQ	Transcriptional regulator
HUK68_03025	ENOG4105JSC	dimethylmenaquinone methyltransferase
HUK68_03045	ENOG4105F27	Major Facilitator
HUK68_03055	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HUK68_03065	ENOG4105BZU	Histidine kinase
HUK68_03080	ENOG4105E0K	tonB-dependent siderophore receptor
HUK68_03100	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HUK68_03105	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HUK68_03110	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HUK68_03120	ENOG4108JQ7	(ABC) transporter
HUK68_03125	ENOG4105C3U	ABC transporter
HUK68_03130	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HUK68_03135	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HUK68_03140	ENOG41080U6	GntR family transcriptional regulator
HUK68_03150	ENOG4105FP9	thiamine pyrophosphate
HUK68_03155	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HUK68_03170	ENOG4105W39	Membrane
HUK68_03180	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HUK68_03185	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HUK68_03190	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HUK68_03195	ENOG4105W2Z	cytochrome C, class I
HUK68_03200	ENOG4105CUB	amino acid
HUK68_03220	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HUK68_03230	ENOG4105VCQ	rubredoxin
HUK68_03235	ENOG4108UNF	response regulator
HUK68_03240	ENOG4105M3Z	response regulator
HUK68_03250	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_03255	ENOG4105CBS	Chea signal transduction histidine kinase
HUK68_03260	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HUK68_03265	ENOG4108UJU	UPF0301 protein
HUK68_03270	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HUK68_03275	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HUK68_03280	ENOG4105CXT	aspartate transcarbamylase
HUK68_03285	ENOG4105CD3	dihydroorotase
HUK68_03290	ENOG4108Z20	Acyl-transferase
HUK68_03295	ENOG4107QXX	ABC transporter
HUK68_03300	ENOG4105EZ7	amino acid ABC transporter
HUK68_03305	ENOG4105DRP	amino acid AbC transporter
HUK68_03310	ENOG4105CDA	abc transporter atp-binding protein
HUK68_03315	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HUK68_03320	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HUK68_03345	ENOG4105EYW	Ion transport protein
HUK68_03350	ENOG4107SQD	Transcriptional regulator, GntR family
HUK68_03355	ENOG4105T38	integral membrane protein
HUK68_03385	ENOG4105DFP	Integrase
HUK68_03545	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HUK68_03550	ENOG4106RE7	Cytochrome
HUK68_03560	ENOG410829K	Lysine exporter protein (Lyse ygga)
HUK68_03570	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HUK68_03575	ENOG4105MJ2	Competence protein
HUK68_03580	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HUK68_03585	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HUK68_03605	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HUK68_03625	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HUK68_03640	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HUK68_03670	ENOG4106H78	methyltransferase
HUK68_03675	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HUK68_03700	ENOG4105BZU	Histidine kinase
HUK68_03705	ENOG4105WH1	Two component transcriptional regulator luxr family
HUK68_03715	ENOG4105D06	uba thif-type nad fad binding protein
HUK68_03720	ENOG4105CN1	protease
HUK68_03725	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HUK68_03730	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HUK68_03735	ENOG4105VW4	glutaredoxin 3
HUK68_03740	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HUK68_03745	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HUK68_03755	ENOG4105RQF	LysR family Transcriptional regulator
HUK68_03760	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HUK68_03765	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HUK68_03780	ENOG4105DJ2	Major Facilitator Superfamily
HUK68_03810	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HUK68_03830	ENOG4105CV6	ABC transporter, permease
HUK68_03845	ENOG4108V0P	LemA family
HUK68_03855	ENOG4105C98	muts2 protein
HUK68_03865	ENOG4105W5Q	DNA repair protein (RadC
HUK68_03870	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HUK68_03875	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HUK68_03880	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HUK68_03905	ENOG4108RRZ	Transcription elongation factor GreB
HUK68_03910	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HUK68_03915	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HUK68_03920	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HUK68_03925	ENOG4105DSJ	YicC domain protein
HUK68_03935	ENOG4108ZF3	Phosphatase
HUK68_03940	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HUK68_03945	ENOG4105CSA	Coproporphyrinogen iii oxidase
HUK68_03970	ENOG4105FDP	GntR family transcriptional regulator
HUK68_03980	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HUK68_03985	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HUK68_03995	ENOG4105CEY	Amp-dependent synthetase and ligase
HUK68_04000	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HUK68_04005	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HUK68_04010	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HUK68_04015	ENOG4108JJB	ABC transporter
HUK68_04025	ENOG4107ZYJ	bioY protein
HUK68_04030	ENOG4107F3J	Amp-dependent synthetase and ligase
HUK68_04035	ENOG4105CHU	acetyl-coa acetyltransferase
HUK68_04065	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_04070	ENOG4105C1G	acyl-Coa dehydrogenase
HUK68_04075	ENOG4105DND	Transcriptional regulator
HUK68_04100	ENOG4106NZI	LysR family Transcriptional regulator
HUK68_04135	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HUK68_04145	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HUK68_04165	ENOG4105F2V	VRR-NUC domain-containing protein
HUK68_04175	ENOG4105CHR	reductase
HUK68_04220	ENOG4105C32	Amino acid ABC transporter (Permease)
HUK68_04230	ENOG4105C0Z	ABC transporter
HUK68_04235	ENOG4108IV0	ABC, transporter
HUK68_04270	ENOG4105C94	Transporter
HUK68_04275	ENOG4108TUY	outer membrane protein PgaA
HUK68_04280	ENOG4107BJW	polysaccharide deacetylase
HUK68_04285	ENOG4105CND	Glycosyl transferase, family 2
HUK68_04300	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HUK68_04320	ENOG4105D5Q	Arginine ornithine antiporter
HUK68_04330	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
HUK68_04335	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HUK68_04345	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HUK68_04375	ENOG4105CH2	amidohydrolase
HUK68_04385	ENOG4108S3W	Anti-feci sigma factor, fecr
HUK68_04390	ENOG4105CNM	Receptor
HUK68_04420	ENOG4105QUC	reductase
HUK68_04425	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
HUK68_04435	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
HUK68_04455	ENOG4105NIV	Esterase
HUK68_04465	ENOG4108S3W	Anti-feci sigma factor, fecr
HUK68_04470	ENOG4108SF5	RNA Polymerase
HUK68_04495	ENOG4105CD5	CoA-binding domain protein
HUK68_04505	ENOG4105ETT	transcriptional Regulator, LysR family
HUK68_04520	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
HUK68_04560	ENOG4105ETE	Transcriptional regulator (LacI family
HUK68_04565	ENOG4105CHR	reductase
HUK68_04575	ENOG4106H3A	restriction
HUK68_04580	ENOG41088T4	Helicase IV
HUK68_04660	ENOG4105E98	transcriptional regulator DeoR family
HUK68_04665	ENOG4108X4D	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HUK68_04670	ENOG4108IJG	ABC transporter substrate-binding protein
HUK68_04675	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HUK68_04680	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HUK68_04690	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HUK68_04695	ENOG4105EQR	Transposase IS116 IS110 IS902
HUK68_04705	ENOG4108NF7	phage-type endonuclease
HUK68_04725	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HUK68_04730	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HUK68_04735	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HUK68_04745	ENOG4105CQM	Urea amidohydrolase subunit alpha
HUK68_04750	ENOG4105KI2	Urea amidohydrolase subunit beta
HUK68_04760	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HUK68_04765	ENOG4105BZU	Histidine kinase
HUK68_04770	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HUK68_04775	ENOG4105JXB	ankyrin repeat-containing protein
HUK68_04785	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HUK68_04790	ENOG4105C32	Amino acid ABC transporter (Permease)
HUK68_04800	ENOG4105C0Z	ABC transporter
HUK68_04805	ENOG4108IV0	ABC, transporter
HUK68_04815	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HUK68_04820	ENOG4108Z6B	deaminase
HUK68_04825	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HUK68_04830	ENOG4105D7T	ABC transporter
HUK68_04835	ENOG4107Z6I	Thiamine biosynthesis protein
HUK68_04845	ENOG4105EW6	flavin reductase domain protein, FMN-binding
HUK68_04850	ENOG4105C6K	Malic enzyme
HUK68_04865	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HUK68_04880	ENOG4107YCY	Transcriptional regulator
HUK68_04885	ENOG4105VT2	5-hydroxyisourate hydrolase
HUK68_04915	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
HUK68_04940	ENOG4105BZU	Histidine kinase
HUK68_04945	ENOG4105C7W	Xanthine dehydrogenase
HUK68_04955	ENOG4105C2J	ABC transporter
HUK68_04960	ENOG4105UIB	(ABC) transporter
HUK68_04985	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HUK68_04990	ENOG4105K59	histidine triad (HIT) protein
HUK68_05000	ENOG4107QUY	Guanine deaminase
HUK68_05005	ENOG4105DHP	deoxycytidine triphosphate deaminase
HUK68_05020	ENOG4105CGZ	zinc metallopeptidase
HUK68_05025	ENOG4105C1J	atp-dependent rna helicase
HUK68_05035	ENOG4105CTX	dehydratase
HUK68_05040	ENOG4105DRR	Transcriptional regulator, GntR family
HUK68_05050	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
HUK68_05055	ENOG4105C5I	Dehydrogenase
HUK68_05065	ENOG4105C26	Dehydrogenase
HUK68_05070	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HUK68_05080	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
HUK68_05085	ENOG4105MSY	salicylate hydroxylase
HUK68_05095	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
HUK68_05100	ENOG4105D03	DNA-3-methyladenine glycosylase II
HUK68_05110	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
HUK68_05115	ENOG4105C85	amino acid
HUK68_05120	ENOG4105DBV	ornithine carbamoyltransferase
HUK68_05125	ENOG4105C8Y	Acetylornithine aminotransferase
HUK68_05135	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
HUK68_05140	ENOG4105CJR	Integral membrane protein (MviN
HUK68_05155	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HUK68_05160	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HUK68_05170	ENOG4105DJ0	Poly(A) Polymerase
HUK68_05175	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUK68_05185	ENOG4108EX3	reductase
HUK68_05205	ENOG410908U	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HUK68_05210	ENOG4105HEI	LysR family (Transcriptional regulator
HUK68_05230	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_05235	ENOG4105UPP	uncharacterized protein ydcA
HUK68_05460	ENOG4105ED4	portal protein
HUK68_05475	ENOG4105C6T	cysteine synthase
HUK68_05485	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HUK68_05490	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HUK68_05535	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HUK68_05540	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HUK68_05545	ENOG4105EM2	membrane
HUK68_05550	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HUK68_05555	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HUK68_05560	ENOG4105KHC	sulfurtransferase
HUK68_05575	ENOG41086K9	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HUK68_05585	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HUK68_05590	ENOG4105CH5	extracellular solute-binding protein, family 7
HUK68_05595	ENOG4105CH5	extracellular solute-binding protein, family 7
HUK68_05610	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HUK68_05615	ENOG4105C26	Dehydrogenase
HUK68_05625	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HUK68_05640	ENOG4108VAC	response regulator
HUK68_05645	ENOG4105C2F	Histidine kinase
HUK68_05655	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HUK68_05665	ENOG4105R1U	AraC Family Transcriptional Regulator
HUK68_05670	ENOG4105DJ2	Major Facilitator Superfamily
HUK68_05675	ENOG4105CHR	reductase
HUK68_05690	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HUK68_05695	ENOG4105CPC	Aldo Keto reductase
HUK68_05710	ENOG4105ECY	inositol monophosphatase
HUK68_05720	ENOG4105D7W	serine acetyltransferase
HUK68_05735	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HUK68_05740	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_05745	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HUK68_05750	ENOG4105N42	UPF0307 protein
HUK68_05755	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HUK68_05785	ENOG4105VCC	30S ribosomal protein S21
HUK68_05790	ENOG4105CBX	hi0933 family
HUK68_05795	ENOG4108S4H	thioesterase Superfamily protein
HUK68_05800	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HUK68_05805	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HUK68_05820	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HUK68_05850	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HUK68_05855	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HUK68_05865	ENOG4105CVE	Lytic murein transglycosylase
HUK68_05870	ENOG4105F8C	transglutaminase domain-containing protein
HUK68_05880	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HUK68_05885	ENOG4105DGU	Histone deacetylase
HUK68_05890	ENOG41060WC	Enoyl-CoA hydratase
HUK68_05895	ENOG4105EGS	Mechanosensitive ion channel
HUK68_05900	ENOG4105BZJ	Electron transfer flavoprotein
HUK68_05905	ENOG4105C10	Electron transfer flavoprotein
HUK68_05915	ENOG4105CSU	acyl-Coa dehydrogenase
HUK68_05935	ENOG4105NXH	GreA GreB family elongation factor
HUK68_05940	ENOG4105C4W	S-formylglutathione hydrolase
HUK68_05945	ENOG4105BZN	citrate synthase
HUK68_05950	ENOG41060IS	Flavinator of succinate dehydrogenase
HUK68_05955	ENOG4105E33	succinate dehydrogenase
HUK68_05960	ENOG4108J01	L-aspartate oxidase
HUK68_05965	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HUK68_05970	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HUK68_05975	ENOG4105FDP	GntR family transcriptional regulator
HUK68_05980	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HUK68_05985	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HUK68_06000	ENOG4107QIJ	Aconitate hydratase 2
HUK68_06010	ENOG4107QM5	aconitate hydratase
HUK68_06015	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HUK68_06020	ENOG4105C01	Dihydroxy-acid dehydratase
HUK68_06030	ENOG41082F9	transcriptional regulator
HUK68_06040	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HUK68_06050	ENOG4105CFP	Peptidase U32
HUK68_06060	ENOG4105E6M	Sulphatase-modifying factor protein
HUK68_06070	ENOG4105H1G	trap transporter solute receptor taxi family
HUK68_06075	ENOG4105D6U	Sodium Glutamate Symporter
HUK68_06090	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HUK68_06095	ENOG4105BZU	Histidine kinase
HUK68_06105	ENOG4105ENH	Sulfatase
HUK68_06130	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HUK68_06155	ENOG4105M8F	Biopolymer transport protein exbD tolR
HUK68_06160	ENOG4105E02	MotA TolQ exbB proton channel
HUK68_06165	ENOG4107YD3	Thioesterase
HUK68_06170	ENOG4105CHM	Aminotransferase
HUK68_06175	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HUK68_06180	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HUK68_06185	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HUK68_06195	ENOG4105D9M	gamma-glutamylcysteine synthetase
HUK68_06210	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HUK68_06215	ENOG4105CH2	amidohydrolase
HUK68_06220	ENOG4108302	MgtC SapB transporter
HUK68_06235	ENOG4105DR9	pseudouridine synthase
HUK68_06265	ENOG4105DR4	Methyltransferase
HUK68_06270	ENOG4105CX6	glutaminyL-tRNA synthetase
HUK68_06280	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HUK68_06290	ENOG4108YZN	class I peptide chain release factor
HUK68_06305	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HUK68_06325	ENOG4105C8N	cysteinyl-tRNA synthetase
HUK68_06335	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HUK68_06340	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HUK68_06345	ENOG4105CFH	Aspartokinase
HUK68_06355	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
HUK68_06375	ENOG4105E2A	Dehydrogenase
HUK68_06385	ENOG4107VMU	Membrane
HUK68_06395	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HUK68_06400	ENOG4105W8H	transhydrogenase (subunit alpha
HUK68_06405	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HUK68_06460	ENOG4105I08	Pseudouridine synthase
HUK68_06470	ENOG4107QUY	Guanine deaminase
HUK68_06475	ENOG4105C2W	permease
HUK68_06480	ENOG4105VEJ	Heat shock protein
HUK68_06485	ENOG4105DHQ	Histidine kinase
HUK68_06535	ENOG4105BZU	Histidine kinase
HUK68_06555	ENOG41065RQ	ADP-ribosylation crystallin J1
HUK68_06585	ENOG4108YXU	transcriptional regulator AsnC family
HUK68_06615	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HUK68_06620	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HUK68_06640	ENOG4105CR8	Transcriptional regulator
HUK68_06645	ENOG4105F27	Major Facilitator
HUK68_06655	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HUK68_06665	ENOG4105CVN	desaturase
HUK68_06670	ENOG4105FE1	phytoene synthase
HUK68_06675	ENOG4105C1J	atp-dependent rna helicase
HUK68_06685	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HUK68_06790	ENOG4105UPP	uncharacterized protein ydcA
HUK68_06930	ENOG4105ED4	portal protein
HUK68_06970	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HUK68_06975	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HUK68_06980	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HUK68_06985	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HUK68_07035	ENOG4105CXN	decarboxylase
HUK68_07055	ENOG4108Z9W	Outer membrane porin
HUK68_07070	ENOG4107EJG	GntR family transcriptional regulator
HUK68_07075	ENOG4105CSH	Transporter
HUK68_07090	ENOG4105EA8	2-Nitropropane dioxygenase
HUK68_07095	ENOG4105CGU	Enoyl-CoA hydratase
HUK68_07115	ENOG4105CP9	extracellular ligand-binding receptor
HUK68_07125	ENOG4105C0Z	ABC transporter
HUK68_07130	ENOG4108IV0	ABC, transporter
HUK68_07135	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HUK68_07145	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HUK68_07165	ENOG4105DUM	transcriptional regulator, lysR family
HUK68_07190	ENOG4105PGM	cation diffusion facilitator family transporter
HUK68_07195	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HUK68_07200	ENOG4105E43	Extracellular solute-binding protein, family 5
HUK68_07205	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HUK68_07210	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HUK68_07215	ENOG4108JQ5	ABC transporter
HUK68_07220	ENOG4105EJC	lysr family transcriptional regulator
HUK68_07235	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HUK68_07240	ENOG4108TFY	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HUK68_07245	ENOG4105QNF	Outer membrane lipoprotein
HUK68_07250	ENOG4108JJ7	ABC transporter
HUK68_07270	ENOG4105QNF	Outer membrane lipoprotein
HUK68_07275	ENOG4106RE7	Cytochrome
HUK68_07280	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HUK68_07290	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HUK68_07295	ENOG4105CHV	Transcription elongation factor NusA
HUK68_07300	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HUK68_07305	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HUK68_07310	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HUK68_07315	ENOG4105CI3	gtp-binding protein typa
HUK68_07320	ENOG4105CGU	Enoyl-CoA hydratase
HUK68_07325	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HUK68_07330	ENOG4108Z1B	Cyclase dehydrase
HUK68_07345	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HUK68_07350	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HUK68_07355	ENOG4105C1V	Peptidase, M16
HUK68_07360	ENOG4105D7W	serine acetyltransferase
HUK68_07370	ENOG410846T	CoA-transferase family III
HUK68_07375	ENOG4108KSA	LysR family transcriptional regulator
HUK68_07385	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HUK68_07390	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_07395	ENOG4108M0I	Transcriptional regulator
HUK68_07430	ENOG4105CDH	Citrulline--aspartate ligase
HUK68_07435	ENOG4105NBK	UPF0345 protein
HUK68_07445	ENOG4105KUZ	arsenate reductase
HUK68_07450	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HUK68_07460	ENOG4105E96	Colicin v production protein
HUK68_07465	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HUK68_07470	ENOG4105C28	cystathionine
HUK68_07475	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HUK68_07530	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
HUK68_07540	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HUK68_07545	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HUK68_07550	ENOG4105ETE	Transcriptional regulator (LacI family
HUK68_07570	ENOG4108WFY	phasin family
HUK68_07580	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HUK68_07590	ENOG4105C5I	Dehydrogenase
HUK68_07615	ENOG4105W4C	monovalent cation H antiporter subunit F
HUK68_07620	ENOG4105SC1	monovalent cation H antiporter subunit E
HUK68_07625	ENOG4107R4Z	monovalent cation h antiporter subunit d
HUK68_07630	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HUK68_07635	ENOG4105D65	subunit l
HUK68_07645	ENOG4105CFV	Tetratricopeptide repeat protein
HUK68_07655	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HUK68_07660	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HUK68_07665	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HUK68_07680	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HUK68_07685	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HUK68_07690	ENOG4105UYK	outer membrane protein a
HUK68_07695	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HUK68_07700	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HUK68_07735	ENOG4105E2Y	ABC, transporter
HUK68_07740	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HUK68_07750	ENOG4105CHR	reductase
HUK68_07775	ENOG410620I	Diguanylate cyclase
HUK68_07785	ENOG4105BZU	Histidine kinase
HUK68_07790	ENOG4105BZU	Histidine kinase
HUK68_07805	ENOG4105FUA	antagonist
HUK68_07810	ENOG4107MMM	Anti-sigma-factor antagonist
HUK68_07855	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HUK68_07865	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
HUK68_07870	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HUK68_07885	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HUK68_07890	ENOG4105DUM	transcriptional regulator, lysR family
HUK68_07900	ENOG4105D7T	ABC transporter
HUK68_07910	ENOG4105I5W	Transporter
HUK68_07925	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
HUK68_07940	ENOG4105DZG	Dehydrogenase
HUK68_07955	ENOG4105UCG	Domain of unknown function (DUF333)
HUK68_07960	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HUK68_07965	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HUK68_07985	ENOG4105E0K	tonB-dependent siderophore receptor
HUK68_07995	ENOG4105DMF	Dehydrogenase
HUK68_08005	ENOG4105JSC	dimethylmenaquinone methyltransferase
HUK68_08010	ENOG4108JQ1	Dehydrogenase
HUK68_08015	ENOG4105C5Q	Transcriptional regulator
HUK68_08020	ENOG4105C7F	AcnD-accessory protein PrpF
HUK68_08025	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HUK68_08040	ENOG4105CHJ	isochorismatase hydrolase
HUK68_08045	ENOG4105EUB	pirin domain protein
HUK68_08050	ENOG4105CC0	LysR family Transcriptional regulator
HUK68_08060	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HUK68_08065	ENOG4105CD8	aminopeptidase N
HUK68_08075	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_08090	ENOG4105IJJ	transcriptional regulator, crp fnr family
HUK68_08100	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HUK68_08105	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HUK68_08125	ENOG4105CPD	ethanolamine ammonia-lyase
HUK68_08130	ENOG4107FQ9	ethanolamine ammonia-lyase
HUK68_08155	ENOG4107TF3	peptidylprolyl cis-trans isomerase
HUK68_08165	ENOG4107835	probably involved in intracellular septation (By similarity)
HUK68_08170	ENOG4105E0X	reductase
HUK68_08175	ENOG4105CNG	UPF0061 protein
HUK68_08180	ENOG4105CEY	Amp-dependent synthetase and ligase
HUK68_08190	ENOG4105C32	Amino acid ABC transporter (Permease)
HUK68_08200	ENOG4105C0Z	ABC transporter
HUK68_08205	ENOG4108IV0	ABC, transporter
HUK68_08210	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HUK68_08215	ENOG4105CHU	acetyl-coa acetyltransferase
HUK68_08220	ENOG4105CSU	acyl-Coa dehydrogenase
HUK68_08225	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HUK68_08230	ENOG4105DHQ	Histidine kinase
HUK68_08240	ENOG4105S7S	phosphonate abc transporter
HUK68_08245	ENOG4105D5T	phosphonate abc transporter
HUK68_08250	ENOG4107T9Q	phosphonate abc transporter
HUK68_08280	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HUK68_08285	ENOG4105CHR	reductase
HUK68_08295	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HUK68_08305	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HUK68_08310	ENOG4105BZS	acriflavin resistance protein
HUK68_08315	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HUK68_08340	ENOG4105BZM	domain protein
HUK68_08370	ENOG4105WH1	Two component transcriptional regulator luxr family
HUK68_08380	ENOG4105DSF	transport protein
HUK68_08405	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HUK68_08410	ENOG4105HHA	aminodeoxychorismate lyase
HUK68_08415	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HUK68_08420	ENOG4107QRG	dna polymerase iii
HUK68_08430	ENOG4105F8V	Hydrolase, tatD family
HUK68_08455	ENOG4105DWT	malate dehydrogenase (quinone)
HUK68_08460	ENOG4105CK2	sodium dicarboxylate symporter
HUK68_08475	ENOG4105CUZ	uba thif-type nad fad binding protein
HUK68_08485	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HUK68_08490	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HUK68_08495	ENOG4105BZ1	(ABC) transporter
HUK68_08510	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HUK68_08520	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HUK68_08525	ENOG4108MG3	formate dehydrogenase
HUK68_08530	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HUK68_08540	ENOG4108REF	Sporulation integral membrane protein ytvi
HUK68_08545	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HUK68_08550	ENOG4105C7S	Dehydrogenase
HUK68_08555	ENOG4107QN2	dihydrolipoyl dehydrogenase
HUK68_08560	ENOG4105D6Z	AFG1 family ATPase
HUK68_08580	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HUK68_08590	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HUK68_08600	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HUK68_08605	ENOG4105W49	UPF0434 protein
HUK68_08610	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HUK68_08615	ENOG4105M8F	Biopolymer transport protein exbD tolR
HUK68_08625	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HUK68_08630	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HUK68_08635	ENOG4105E9K	Isocitrate dehydrogenase
HUK68_08660	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HUK68_08670	ENOG4105CH2	amidohydrolase
HUK68_08710	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HUK68_08715	ENOG4108VP3	Lysine exporter protein (LysE YggA)
HUK68_08735	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HUK68_08745	ENOG4105C1G	acyl-Coa dehydrogenase
HUK68_08755	ENOG4105C26	Dehydrogenase
HUK68_08780	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HUK68_08785	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HUK68_08790	ENOG4105CPC	Aldo Keto reductase
HUK68_08805	ENOG4107QN2	dihydrolipoyl dehydrogenase
HUK68_08810	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HUK68_08820	ENOG4105CCT	upf0313 protein
HUK68_08825	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
HUK68_08830	ENOG4107HP6	Transcriptional regulator
HUK68_08840	ENOG4107QNJ	CoA-transferase subunit B
HUK68_08845	ENOG4105CHU	acetyl-coa acetyltransferase
HUK68_08850	ENOG4105CHR	reductase
HUK68_08860	ENOG4105CGF	Aromatic amino acid aminotransferase
HUK68_08870	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HUK68_08875	ENOG4105C3J	Cysteine desulfurase
HUK68_08880	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HUK68_08885	ENOG4108Z4V	iron-sulfur cluster assembly
HUK68_08895	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HUK68_08900	ENOG4108ZIT	Ferredoxin, 2FE-2S
HUK68_08905	ENOG4107RZZ	dna polymerase iii epsilon subunit
HUK68_08950	ENOG4108Z9W	Outer membrane porin
HUK68_08960	ENOG4105CC9	acyl-Coa dehydrogenase
HUK68_08970	ENOG4105CHU	acetyl-coa acetyltransferase
HUK68_08975	ENOG4105CEY	Amp-dependent synthetase and ligase
HUK68_08980	ENOG4108JQ7	(ABC) transporter
HUK68_08985	ENOG4105C3U	ABC transporter
HUK68_08990	ENOG4105DEF	Extracellular solute-binding protein, family 5
HUK68_08995	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HUK68_09020	ENOG4105BZJ	Electron transfer flavoprotein
HUK68_09025	ENOG4105C10	Electron transfer flavoprotein
HUK68_09030	ENOG4108KB2	LysR family Transcriptional regulator
HUK68_09040	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_09045	ENOG4105D2B	acyl-CoA dehydrogenase
HUK68_09050	ENOG4105D2B	acyl-CoA dehydrogenase
HUK68_09070	ENOG4105D5U	fad dependent oxidoreductase
HUK68_09090	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HUK68_09095	ENOG4105E66	phosphoriboisomerase A
HUK68_09110	ENOG4105DGW	oligopeptidase A
HUK68_09115	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HUK68_09120	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HUK68_09125	ENOG4105BZU	Histidine kinase
HUK68_09130	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HUK68_09135	ENOG4107QSN	dihydrolipoamide acetyltransferase
HUK68_09140	ENOG4107QN2	dihydrolipoyl dehydrogenase
HUK68_09150	ENOG4105D4Y	metalloprotease
HUK68_09170	ENOG4108YS0	lipoprotein YafL
HUK68_09180	ENOG4107QKV	phosphomannomutase
HUK68_09185	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HUK68_09190	ENOG4105DFG	type I secretion outer membrane protein
HUK68_09195	ENOG4105C72	UPF0176 protein
HUK68_09200	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HUK68_09215	ENOG4108R86	Transcriptional regulator
HUK68_09220	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HUK68_09240	ENOG4105UGU	tonB-dependent Receptor
HUK68_09250	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HUK68_09255	ENOG4108UYE	Lactoylglutathione lyase
HUK68_09275	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HUK68_09280	ENOG4105DUM	transcriptional regulator, lysR family
HUK68_09295	ENOG4107XKF	NMT1 THI5 Like Domain Protein
HUK68_09300	ENOG4108IY8	ABC, transporter
HUK68_09310	ENOG4108Z6B	deaminase
HUK68_09320	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HUK68_09355	ENOG4105K56	Transcriptional regulator
HUK68_09360	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HUK68_09365	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HUK68_09415	ENOG4107QX3	carboxylase
HUK68_09420	ENOG4105DJT	lAO AO transport system ATPase
HUK68_09430	ENOG4105DRR	Transcriptional regulator, GntR family
HUK68_09440	ENOG4105ETT	transcriptional Regulator, LysR family
HUK68_09455	ENOG4105E1J	oxidoreductase
HUK68_09465	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HUK68_09470	ENOG4105C3U	ABC transporter
HUK68_09475	ENOG4108JQ7	(ABC) transporter
HUK68_09480	ENOG4105DEF	Extracellular solute-binding protein, family 5
HUK68_09500	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HUK68_09510	ENOG4108R3D	Electron transport complex
HUK68_09515	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
HUK68_09520	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HUK68_09525	ENOG4105CZX	twitching motility protein
HUK68_09530	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HUK68_09535	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HUK68_09540	ENOG4105C5H	ABC transporter
HUK68_09545	ENOG4105CHR	reductase
HUK68_09550	ENOG4105CHU	acetyl-coa acetyltransferase
HUK68_09555	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HUK68_09565	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HUK68_09570	ENOG4108RXX	maleylacetoacetate isomerase
HUK68_09580	ENOG4105E09	nadh pyrophosphatase
HUK68_09600	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HUK68_09610	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HUK68_09615	ENOG4105KK4	UPF0060 membrane protein
HUK68_09620	ENOG4105BZU	Histidine kinase
HUK68_09625	ENOG4108I0Y	(ABC) transporter
HUK68_09630	ENOG4108UJV	acyl-CoA thioesterase i
HUK68_09645	ENOG4105C28	cystathionine
HUK68_09655	ENOG4105CHH	sulfate transporter
HUK68_09670	ENOG4105C72	UPF0176 protein
HUK68_09675	ENOG4108VBZ	doxx family
HUK68_09680	ENOG4105EQ1	Transcriptional regulator
HUK68_09685	ENOG4105EWK	phytoene
HUK68_09690	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HUK68_09695	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HUK68_09700	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HUK68_09710	ENOG4105C6Z	Gluconate
HUK68_09715	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HUK68_09720	ENOG4105CSH	Transporter
HUK68_09725	ENOG4105E2S	oxidase) subunit II
HUK68_09730	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HUK68_09735	ENOG4105CCU	oxidase (Subunit III)
HUK68_09740	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HUK68_09750	ENOG4105TX3	Histidine kinase
HUK68_09755	ENOG4108UYB	regulatoR
HUK68_09760	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HUK68_09765	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HUK68_09780	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HUK68_09795	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HUK68_09805	ENOG4108K5H	permease YjgP YjgQ family protein
HUK68_09815	ENOG4107R11	Transcriptional regulator
HUK68_09820	ENOG4105CHM	Aminotransferase
HUK68_09825	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HUK68_09840	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HUK68_09850	ENOG4105C03	ribonuclease
HUK68_09855	ENOG4108Z03	MAF-like protein
HUK68_09860	ENOG4105BZG	amino acid carrier protein
HUK68_09865	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HUK68_09870	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HUK68_09875	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HUK68_09880	ENOG4105C12	Phosphoribosylglycinamide synthetase
HUK68_09885	ENOG4105CDY	transcriptional regulatory protein
HUK68_09890	ENOG4105D7A	ATP-binding protein
HUK68_09910	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HUK68_09915	ENOG4105CDY	transcriptional regulatory protein
HUK68_09920	ENOG4105D8V	Glucose sorbosone dehydrogenase
HUK68_09925	ENOG4107T9Q	phosphonate abc transporter
HUK68_09930	ENOG4105BZU	Histidine kinase
HUK68_09940	ENOG4105CJB	Exodeoxyribonuclease I
HUK68_09945	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HUK68_09950	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HUK68_09955	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HUK68_09960	ENOG4105C0B	DNA polymerase III (alpha subunit)
HUK68_09970	ENOG4105DVT	helicase
HUK68_09975	ENOG4105BZU	Histidine kinase
HUK68_10000	ENOG4105BZU	Histidine kinase
HUK68_10010	ENOG4108UHU	Aldolase
HUK68_10015	ENOG4105C01	Dihydroxy-acid dehydratase
HUK68_10025	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HUK68_10030	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HUK68_10035	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HUK68_10040	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HUK68_10045	ENOG4105K2J	Transcriptional regulator
HUK68_10055	ENOG4107S7U	Sulfide dehydrogenase
HUK68_10085	ENOG4105CAU	Arsenical resistance protein, ArsH
HUK68_10100	ENOG4105D6J	arsenicaL-resistance protein
HUK68_10110	ENOG41085FC	arsR family transcriptional regulator
HUK68_10160	ENOG4107YH6	single-stranded DNA-binding protein
HUK68_10165	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HUK68_10315	ENOG4105W5Q	DNA repair protein (RadC
HUK68_10350	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
HUK68_10370	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HUK68_10375	ENOG4105D1H	recombination factor protein RarA
HUK68_10385	ENOG4105C4W	S-formylglutathione hydrolase
HUK68_10430	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HUK68_10440	ENOG4107RSM	transcriptional regulator
HUK68_10450	ENOG4106NZI	LysR family Transcriptional regulator
HUK68_10465	ENOG4105EZR	dyp-type peroxidase family protein
HUK68_10475	ENOG4105D3G	Pseudouridine synthase
HUK68_10480	ENOG41066T0	asmA family
HUK68_10485	ENOG4108ESY	Metal dependent phosphohydrolase
HUK68_10500	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HUK68_10505	ENOG4105CH6	catalase
HUK68_10520	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HUK68_10530	ENOG4105C7J	ABC transporter, permease
HUK68_10540	ENOG4108IQI	permease
HUK68_10555	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HUK68_10565	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUK68_10575	ENOG4105D3G	Pseudouridine synthase
HUK68_10580	ENOG4105CP9	extracellular ligand-binding receptor
HUK68_10585	ENOG4105C32	Amino acid ABC transporter (Permease)
HUK68_10590	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HUK68_10595	ENOG4105C0Z	ABC transporter
HUK68_10600	ENOG4108IV0	ABC, transporter
HUK68_10605	ENOG410904N	short-chain dehydrogenase reductase
HUK68_10615	ENOG4108W5M	transcriptional regulator
HUK68_10620	ENOG4105EQ0	Major Facilitator superfamily
HUK68_10625	ENOG4105CWB	LysR family transcriptional Regulator
HUK68_10635	ENOG4105CHJ	isochorismatase hydrolase
HUK68_10680	ENOG4108MIB	
HUK68_10705	ENOG4105E0K	tonB-dependent siderophore receptor
HUK68_10720	ENOG4105DND	Transcriptional regulator
HUK68_10725	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
HUK68_10740	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HUK68_10755	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HUK68_10770	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HUK68_10785	ENOG4105DHU	Bile acid
HUK68_10825	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HUK68_10835	ENOG4107YB6	acetyltransferase, (GNAT) family
HUK68_10845	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HUK68_10850	ENOG4105CVE	Lytic murein transglycosylase
HUK68_10855	ENOG4105EHV	domain protein
HUK68_10860	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HUK68_10870	ENOG4105ENH	Sulfatase
HUK68_10880	ENOG41063Z6	transcriptional regulator, lysR family
HUK68_10890	ENOG4107YZX	Universal stress protein
HUK68_10900	ENOG4105EQX	glucarate dehydratase
HUK68_10940	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
HUK68_10945	ENOG4107HP6	Transcriptional regulator
HUK68_10950	ENOG4105EMY	transcriptional regulator
HUK68_10965	ENOG4105CPC	Aldo Keto reductase
HUK68_10985	ENOG4105GAK	amidohydrolase 2
HUK68_10995	ENOG4105KHM	amidohydrolase 2
HUK68_11000	ENOG4105D2S	major facilitator superfamily
HUK68_11010	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
HUK68_11045	ENOG4105CEY	Amp-dependent synthetase and ligase
HUK68_11050	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
HUK68_11060	ENOG4105CQ7	ATP-dependent helicase
HUK68_11065	ENOG4108EKC	n-acetylglutamate synthase
HUK68_11090	ENOG4108R99	pseudouridine synthase
HUK68_11095	ENOG4107R11	Transcriptional regulator
HUK68_11110	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HUK68_11115	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HUK68_11120	ENOG4105EN6	Membrane
HUK68_11125	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HUK68_11155	ENOG4108Z4U	Ferredoxin
HUK68_11160	ENOG4105CAY	ferredoxin--nadp reductase
HUK68_11170	ENOG4105DJ4	phosphatidylserine decarboxylase
HUK68_11175	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HUK68_11200	ENOG4108Z9W	Outer membrane porin
HUK68_11225	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HUK68_11230	ENOG4108IJ6	ABC transporter
HUK68_11235	ENOG4105ECW	sulfate abc transporter
HUK68_11240	ENOG4108I5D	sulfate abc transporter
HUK68_11245	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HUK68_11255	ENOG4105JQN	Transcriptional regulator
HUK68_11260	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HUK68_11270	ENOG4105CHB	tonB-dependent Receptor
HUK68_11280	ENOG4105D01	(LipO)protein
HUK68_11285	ENOG4108UMI	ABC transporter, permease
HUK68_11290	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HUK68_11295	ENOG4105D01	(LipO)protein
HUK68_11315	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HUK68_11320	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HUK68_11325	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HUK68_11330	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HUK68_11335	ENOG4105VJV	50s ribosomal protein L35
HUK68_11340	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HUK68_11345	ENOG4105C22	threonyL-tRNA synthetase
HUK68_11350	ENOG4108JIK	carboxylase
HUK68_11355	ENOG4105P4J	Allophanate hydrolase, subunit 1
HUK68_11360	ENOG4105E7W	lamb ycsf family protein
HUK68_11390	ENOG4108I9X	Isocitrate lyase
HUK68_11410	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HUK68_11420	ENOG4108JJA	ABC, transporter
HUK68_11505	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HUK68_11530	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HUK68_11540	ENOG4105KHC	sulfurtransferase
HUK68_11545	ENOG41066VF	YeeE YedE family protein
HUK68_11555	ENOG4105CGH	5'-nucleotidase
HUK68_11560	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HUK68_11565	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HUK68_11590	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HUK68_11605	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HUK68_11610	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HUK68_11620	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HUK68_11635	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HUK68_11640	ENOG4105DZ1	carboxypeptidase
HUK68_11650	ENOG4105E0K	tonB-dependent siderophore receptor
HUK68_11655	ENOG4107E2E	PKHD-type hydroxylase
HUK68_11680	ENOG4105SG9	biopolymer transport protein, ExbD
HUK68_11690	ENOG4108ZJF	Glcg protein
HUK68_11695	ENOG4108MN8	Membrane
HUK68_11705	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HUK68_11710	ENOG4105KXX	peptidase s58 dmpa
HUK68_11715	ENOG4105C5H	ABC transporter
HUK68_11720	ENOG4105C1J	atp-dependent rna helicase
HUK68_11730	ENOG4105D78	K07001 NTE family protein
HUK68_11740	ENOG4108M0I	Transcriptional regulator
HUK68_11745	ENOG4105DHU	Bile acid
HUK68_11750	ENOG4105D44	asparaginase
HUK68_11755	ENOG4108UMI	ABC transporter, permease
HUK68_11760	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HUK68_11765	ENOG4105EQX	glucarate dehydratase
HUK68_11775	ENOG4105DIQ	Transcriptional regulator
HUK68_11785	ENOG4105CXK	mandelate racemase muconate lactonizing
HUK68_11790	ENOG4105DUM	transcriptional regulator, lysR family
HUK68_11795	ENOG4108NVM	synthesis repressor PhaR
HUK68_11800	ENOG4108JGH	Tetr family transcriptional regulator
HUK68_11805	ENOG4105DZG	Dehydrogenase
HUK68_11810	ENOG4108JPW	Aminotransferase
HUK68_11815	ENOG4105ED1	spovr family
HUK68_11820	ENOG4106AKX	UPF0229 protein
HUK68_11825	ENOG4105CYN	Serine protein kinase
HUK68_11830	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HUK68_11835	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HUK68_11840	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HUK68_11845	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HUK68_11855	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HUK68_11865	ENOG4105GR3	Histidine kinase
HUK68_11915	ENOG4105CNM	Receptor
HUK68_11955	ENOG4105WH1	Two component transcriptional regulator luxr family
HUK68_11990	ENOG4105BZU	Histidine kinase
HUK68_12000	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HUK68_12010	ENOG4105DTD	Dehydrogenase
HUK68_12025	ENOG4105E0F	Histidine kinase
HUK68_12030	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
HUK68_12035	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
HUK68_12040	ENOG4108JA2	transcriptioN-repair coupling factor
HUK68_12050	ENOG4105EAC	phosphoserine phosphatase
HUK68_12060	ENOG4105VRT	cytoplasmic protein
HUK68_12070	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HUK68_12075	ENOG4105EHG	Permease protein
HUK68_12090	ENOG4105D01	(LipO)protein
HUK68_12095	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HUK68_12100	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HUK68_12120	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HUK68_12125	ENOG4105CSM	endonuclease III
HUK68_12130	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_12140	ENOG4105CSU	acyl-Coa dehydrogenase
HUK68_12145	ENOG4107RSM	transcriptional regulator
HUK68_12150	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HUK68_12165	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HUK68_12175	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HUK68_12180	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
HUK68_12185	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HUK68_12190	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HUK68_12195	ENOG4105EHG	Permease protein
HUK68_12205	ENOG4108YZT	Adenosylcobinamide kinase
HUK68_12210	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HUK68_12235	ENOG4105VDW	Csbd family
HUK68_12240	ENOG4105BZU	Histidine kinase
HUK68_12255	ENOG4105D4P	Coproporphyrinogen iii oxidase
HUK68_12260	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HUK68_12290	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HUK68_12300	ENOG4105C59	p-type ATPase
HUK68_12310	ENOG4105CEY	Amp-dependent synthetase and ligase
HUK68_12330	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HUK68_12345	ENOG4105W2Z	cytochrome C, class I
HUK68_12355	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HUK68_12360	ENOG4108TEB	UPF0114 protein
HUK68_12365	ENOG4108IJ7	Glycine betaine
HUK68_12370	ENOG4108HQS	Glycine betaine
HUK68_12375	ENOG4105GIJ	Glycine betaine
HUK68_12400	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HUK68_12405	ENOG4108VKG	metal-dependent hydrolase
HUK68_12415	ENOG4105D4A	Cell wall formation (By similarity)
HUK68_12420	ENOG4108VPT	UPF0234 protein
HUK68_12425	ENOG4108WIW	Aspartyl protease
HUK68_12435	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HUK68_12440	ENOG4108Z66	YbaK ebsC protein
HUK68_12445	ENOG4105CPC	Aldo Keto reductase
HUK68_12465	ENOG4108K2P	TRANSCRIPTIONal
HUK68_12470	ENOG4108JJ6	Type I secretion system ATPase
HUK68_12475	ENOG4108JJ6	Type I secretion system ATPase
HUK68_12485	ENOG4108JJ6	Type I secretion system ATPase
HUK68_12490	ENOG4108JJ6	Type I secretion system ATPase
HUK68_12505	ENOG4105CUJ	penicillin amidase
HUK68_12520	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HUK68_12525	ENOG4108Z6B	deaminase
HUK68_12530	ENOG4105D05	Receptor
HUK68_12535	ENOG4107QKW	extracellular solute-binding protein family 1
HUK68_12540	ENOG4105E5Q	amino acid AbC transporter
HUK68_12545	ENOG4108UCS	ABC, transporter
HUK68_12550	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HUK68_12555	ENOG41067HS	methyltransferase
HUK68_12560	ENOG4105CJW	magnesium transporter
HUK68_12580	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HUK68_12590	ENOG4105CKW	Inner membrane protein yedI
HUK68_12600	ENOG4105EHG	Permease protein
HUK68_12605	ENOG4107R4I	Periplasmic binding protein
HUK68_12610	ENOG4106QJH	hemin transport protein
HUK68_12620	ENOG4105D05	Receptor
HUK68_12625	ENOG4105C84	Histidine ammonia-lyase
HUK68_12630	ENOG4105CGP	Urocanate hydratase
HUK68_12635	ENOG4105CI2	imidazolone-5-propionate hydrolase
HUK68_12645	ENOG4105CNM	Receptor
HUK68_12660	ENOG4108ETH	Formylglycinamide ribotide synthetase
HUK68_12665	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HUK68_12675	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HUK68_12710	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HUK68_12715	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HUK68_12720	ENOG41069M3	Transcriptional regulator
HUK68_12725	ENOG41061WM	D-Alanyl-D-Alanine
HUK68_12730	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HUK68_12735	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HUK68_12740	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HUK68_12745	ENOG4108ZP8	Acetolactate synthase small subunit
HUK68_12750	ENOG4105C7K	acetolactate synthase
HUK68_12755	ENOG4105JVQ	RNA Polymerase
HUK68_12775	ENOG41080IJ	Diacylglycerol kinase
HUK68_12780	ENOG4108URH	decarboxylase
HUK68_12800	ENOG4105CY2	Citrate transporter
HUK68_12805	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_12810	ENOG4108V3W	Chemotaxis protein, CheW
HUK68_12815	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_12820	ENOG4105F0N	pyrophosphate phospho-hydrolase
HUK68_12835	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HUK68_12840	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HUK68_12845	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HUK68_12850	ENOG4105BZU	Histidine kinase
HUK68_12860	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HUK68_12865	ENOG4105D1A	Methyltransferase
HUK68_12870	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HUK68_12875	ENOG4105E9H	Lytic Murein transglycosylase
HUK68_12885	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HUK68_12890	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HUK68_12895	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HUK68_12900	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_12920	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HUK68_12925	ENOG4105NRA	50s ribosomal protein l31 type b
HUK68_12940	ENOG4107QI1	Mate efflux family protein
HUK68_12945	ENOG4105BZU	Histidine kinase
HUK68_12950	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HUK68_12955	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HUK68_12960	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HUK68_12965	ENOG4105E2Z	phosphate ABC transporter (Permease
HUK68_12970	ENOG4105C8U	phosphate abc transporter
HUK68_12975	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HUK68_12985	ENOG4105C9X	ppx gppa phosphatase
HUK68_12990	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HUK68_12995	ENOG4105C9X	ppx gppa phosphatase
HUK68_13000	ENOG4105BZU	Histidine kinase
HUK68_13005	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HUK68_13010	ENOG4105EEI	dihydropteroate synthase
HUK68_13015	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HUK68_13020	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HUK68_13025	ENOG4105HBR	Rna-binding protein
HUK68_13040	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HUK68_13045	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HUK68_13055	ENOG4108RWN	rrna methyltransferase
HUK68_13060	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HUK68_13065	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HUK68_13070	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HUK68_13075	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HUK68_13080	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HUK68_13095	ENOG4105DZP	Membrane-associated zinc metalloprotease
HUK68_13100	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HUK68_13105	ENOG4105KNE	Phosphatidate cytidylyltransferase
HUK68_13110	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HUK68_13115	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HUK68_13120	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HUK68_13125	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HUK68_13130	ENOG4105CE9	30S ribosomal protein S2
HUK68_13140	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HUK68_13145	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HUK68_13150	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HUK68_13195	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HUK68_13200	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HUK68_13205	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HUK68_13215	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HUK68_13230	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HUK68_13240	ENOG4107S2Z	UPF0761 membrane protein
HUK68_13275	ENOG4107QXX	ABC transporter
HUK68_13280	ENOG4105EZ7	amino acid ABC transporter
HUK68_13285	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HUK68_13295	ENOG4105DIJ	Phosphoethanolamine transferase
HUK68_13300	ENOG4105ECM	Sensor protein basS pmrB
HUK68_13305	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HUK68_13320	ENOG4105DIN	metallophosphoesterase
HUK68_13325	ENOG4105UEI	Transcriptional Regulator AraC Family
HUK68_13330	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HUK68_13345	ENOG4105EXW	epimerase dehydratase
HUK68_13385	ENOG4107RUY	(E1 component), alpha subunit
HUK68_13390	ENOG4105CPP	Dehydrogenase, E1 component
HUK68_13400	ENOG4107S1Q	Phosphatase
HUK68_13420	ENOG4108594	Permease of the drug metabolite transporter
HUK68_13435	ENOG4105D7T	ABC transporter
HUK68_13440	ENOG4105I5W	Transporter
HUK68_13450	ENOG4105FDT	acyl-CoA dehydrogenase
HUK68_13455	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HUK68_13470	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HUK68_13480	ENOG4108T2C	cysteine dioxygenase type I
HUK68_13520	ENOG4105BZU	Histidine kinase
HUK68_13545	ENOG4105CGK	Exodeoxyribonuclease III
HUK68_13555	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HUK68_13560	ENOG4105CUX	Signal transduction histidine kinase
HUK68_13600	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HUK68_13605	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HUK68_13610	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HUK68_13615	ENOG4105EPW	hflc protein
HUK68_13620	ENOG4107QJR	hflk protein
HUK68_13625	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HUK68_13630	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HUK68_13635	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HUK68_13640	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HUK68_13650	ENOG4105CUT	histidyl-tRNA synthetase
HUK68_13655	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HUK68_13670	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HUK68_13675	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HUK68_13680	ENOG4105FE9	pseudouridine synthase
HUK68_13685	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HUK68_13690	ENOG4105C34	Pseudouridine synthase
HUK68_13695	ENOG4108K5P	(LipO)protein
HUK68_13700	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HUK68_13705	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HUK68_13715	ENOG4105D6U	Sodium Glutamate Symporter
HUK68_13720	ENOG4107RZC	phospholipase d
HUK68_13730	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HUK68_13745	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HUK68_13770	ENOG4108Z6B	deaminase
HUK68_13790	ENOG4107TTD	cytosine deaminase
HUK68_13795	ENOG4107Z5Z	endoribonuclease L-PSP
HUK68_13815	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HUK68_13830	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_13835	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HUK68_13840	ENOG4108R4R	Iron-regulated virulence regulatory protein
HUK68_13850	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HUK68_13855	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HUK68_13860	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HUK68_13865	ENOG4108JU3	Alkyl hydroperoxide reductase
HUK68_13870	ENOG4105D3R	alkyl hydroperoxide reductase
HUK68_13875	ENOG4108UQY	Iron-storage protein
HUK68_13880	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HUK68_13895	ENOG4108EC8	DNA internalization-related competence protein ComEC
HUK68_13905	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HUK68_13910	ENOG4105E4C	Lytic transglycosylase catalytic
HUK68_13915	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HUK68_13935	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HUK68_13940	ENOG4105GJM	(LipO)protein
HUK68_13950	ENOG4105EZE	Cupin 4 family protein
HUK68_13975	ENOG4105C0Z	ABC transporter
HUK68_13980	ENOG4108IV0	ABC, transporter
HUK68_13990	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HUK68_14010	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HUK68_14015	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HUK68_14020	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HUK68_14030	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HUK68_14035	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HUK68_14050	ENOG4108Z0R	Transferase
HUK68_14055	ENOG4105ED9	Protein of unknown function (DUF455)
HUK68_14060	ENOG4105D58	Diguanylate phosphodiesterase
HUK68_14065	ENOG4105D58	Diguanylate phosphodiesterase
HUK68_14075	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HUK68_14085	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HUK68_14090	ENOG4105K8N	protein family UPF0079, ATPase
HUK68_14095	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HUK68_14105	ENOG4105DQR	SNARE associated Golgi
HUK68_14115	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HUK68_14120	ENOG4105D82	Glutamate dehydrogenase
HUK68_14130	ENOG4105E5G	Alpha beta hydrolase fold
HUK68_14140	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HUK68_14145	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HUK68_14180	ENOG4105C32	Amino acid ABC transporter (Permease)
HUK68_14190	ENOG4108IV0	ABC, transporter
HUK68_14195	ENOG4105C0Z	ABC transporter
HUK68_14210	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HUK68_14215	ENOG4105C8S	subunit m
HUK68_14220	ENOG4105D65	subunit l
HUK68_14225	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HUK68_14230	ENOG4105DF2	NADH dehydrogenase subunit j
HUK68_14235	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HUK68_14240	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HUK68_14245	ENOG4108IEH	NADH dehydrogenase subunit g
HUK68_14250	ENOG4107QIZ	NADH dehydrogenase
HUK68_14260	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HUK68_14265	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUK68_14270	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HUK68_14275	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUK68_14285	ENOG4107EJC	Preprotein translocase subunit SecG
HUK68_14290	ENOG4105CP7	Triose-phosphate isomerase
HUK68_14300	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HUK68_14305	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HUK68_14345	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HUK68_14350	ENOG4108R6K	riboflavin synthase, subunit alpha
HUK68_14355	ENOG4107RZC	phospholipase d
HUK68_14360	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HUK68_14370	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HUK68_14380	ENOG4107RGH	Aldehyde dehydrogenase
HUK68_14390	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HUK68_14395	ENOG4108ZAF	Molybdopterin
HUK68_14420	ENOG4105M00	molybdopterin converting factor, subunit 1
HUK68_14425	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HUK68_14430	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HUK68_14440	ENOG4105D6E	homoserine dehydrogenase
HUK68_14445	ENOG4105CHM	Aminotransferase
HUK68_14455	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUK68_14460	ENOG4108IAB	Phoh family
HUK68_14480	ENOG4105CDU	Replicative dna helicase
HUK68_14485	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HUK68_14490	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HUK68_14500	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HUK68_14505	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUK68_14510	ENOG4105CFG	Acts as a chaperone (By similarity)
HUK68_14515	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HUK68_14525	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HUK68_14530	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HUK68_14535	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HUK68_14550	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HUK68_14560	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HUK68_14565	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HUK68_14570	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HUK68_14575	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HUK68_14580	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HUK68_14585	ENOG4108VIA	integral membrane protein
HUK68_14595	ENOG4105CRK	lysyL-tRNA synthetase
HUK68_14600	ENOG4108KXV	response regulator
HUK68_14620	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HUK68_14625	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HUK68_14630	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HUK68_14635	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HUK68_14640	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HUK68_14645	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HUK68_14655	ENOG4105C3F	Signal peptidase i
HUK68_14660	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HUK68_14665	ENOG4105C0H	protease
HUK68_14670	ENOG41069PW	sigma-e factor negative regulatory protein
HUK68_14675	ENOG4105EMN	RNA polymerase sigma factor
HUK68_14685	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HUK68_14690	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HUK68_14695	ENOG4105CHR	reductase
HUK68_14700	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HUK68_14705	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HUK68_14710	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HUK68_14715	ENOG4105VGS	50s ribosomal protein l32
HUK68_14720	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HUK68_14725	ENOG4108UHJ	MAF-like protein
HUK68_14730	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HUK68_14755	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HUK68_14765	ENOG4105EI2	Pseudouridine synthase
HUK68_14770	ENOG4105C03	ribonuclease
HUK68_14775	ENOG4105D1Q	UPF0246 protein
HUK68_14785	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HUK68_14790	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HUK68_14805	ENOG4105DMF	Dehydrogenase
HUK68_14810	ENOG4105BZ4	penicillin-binding protein
HUK68_14820	ENOG4105DRS	transport system, permease
HUK68_14835	ENOG4108IJ9	(ABC) transporter
HUK68_14845	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HUK68_14850	ENOG4105CH7	arginosuccinase
HUK68_14860	ENOG4108NEV	two component transcriptional regulator, LytTR family
HUK68_14870	ENOG4105C2M	dna polymerase I
HUK68_14880	ENOG4105CUV	Homoserine Kinase
HUK68_14900	ENOG4105C4R	Atp-dependent dna helicase
HUK68_14905	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
HUK68_14910	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HUK68_14940	ENOG4105C2C	drug resistance transporter, Bcr CflA
HUK68_14945	ENOG4105C1J	atp-dependent rna helicase
HUK68_14950	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HUK68_14955	ENOG4105D0M	Protease HtpX homolog
HUK68_14960	ENOG41090A4	Pterin carbinolamine dehydratase
HUK68_14965	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HUK68_14970	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HUK68_14980	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HUK68_14985	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HUK68_14990	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HUK68_14995	ENOG4105K5M	30s ribosomal protein S16
HUK68_15010	ENOG4107QXV	Phosphate transporter
HUK68_15015	ENOG4107GRR	phosphate transport regulator
HUK68_15020	ENOG4105D1H	recombination factor protein RarA
HUK68_15025	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HUK68_15030	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HUK68_15035	ENOG4105CNU	cell division protein FtsK
HUK68_15040	ENOG4105C3M	thioredoxin reductase
HUK68_15045	ENOG4105KDC	50s ribosomal protein l28
HUK68_15050	ENOG4105W0E	50S ribosomal protein L33
HUK68_15055	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HUK68_15075	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HUK68_15080	ENOG4108YXG	UPF0502 protein
HUK68_15085	ENOG4105CC9	acyl-Coa dehydrogenase
HUK68_15090	ENOG4105C1G	acyl-Coa dehydrogenase
HUK68_15095	ENOG4105FFC	UPF0187 protein
HUK68_15100	ENOG4108R5S	membrane
HUK68_15120	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HUK68_15135	ENOG4105DTN	riboflavin biosynthesis protein ribF
HUK68_15140	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HUK68_15145	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HUK68_15150	ENOG4105EAM	Na Pi-cotransporter
HUK68_15160	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HUK68_15185	ENOG4107QHF	type ii secretion system protein e
HUK68_15205	ENOG4105EYA	deoxyribonuclease
HUK68_15210	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HUK68_15215	ENOG4105D60	lipoprotein releasing system transmembrane protein
HUK68_15225	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HUK68_15230	ENOG4105DB7	PHP domain protein
HUK68_15235	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HUK68_15240	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_15245	ENOG4108Z4T	Peptidase M50
HUK68_15250	ENOG4105C31	Tryptophanyl-tRNA synthetase
HUK68_15295	ENOG4105FDK	ABC transporter
HUK68_15360	ENOG4108ESY	Metal dependent phosphohydrolase
HUK68_15370	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUK68_15375	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HUK68_15380	ENOG4108JQ1	Dehydrogenase
HUK68_15390	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HUK68_15395	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HUK68_15400	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HUK68_15405	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HUK68_15410	ENOG4105CEN	a g-specific adenine glycosylase
HUK68_15415	ENOG410890F	Dynamin family
HUK68_15420	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HUK68_15425	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
HUK68_15430	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HUK68_15435	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HUK68_15445	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HUK68_15450	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HUK68_15455	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HUK68_15460	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HUK68_15470	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HUK68_15480	ENOG4108JQ7	(ABC) transporter
HUK68_15485	ENOG4105DEF	Extracellular solute-binding protein, family 5
HUK68_15490	ENOG410829K	Lysine exporter protein (Lyse ygga)
HUK68_15500	ENOG4105EUJ	GTP cyclohydrolase i
HUK68_15505	ENOG4105X23	Endonuclease Exonuclease phosphatase
HUK68_15515	ENOG4105C9M	aspartyl-trna synthetase
HUK68_15535	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HUK68_15550	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HUK68_15575	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HUK68_15585	ENOG4108IJ9	(ABC) transporter
HUK68_15590	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
HUK68_15605	ENOG4108MGI	Transcriptional regulator
HUK68_15615	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HUK68_15620	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HUK68_15635	ENOG4105C37	(CBS) domain
HUK68_15640	ENOG4105E4C	Lytic transglycosylase catalytic
HUK68_15645	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HUK68_15650	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HUK68_15655	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HUK68_15660	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUK68_15665	ENOG4105K46	50S ribosomal protein l27
HUK68_15670	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HUK68_15675	ENOG4105EAH	synthase
HUK68_15685	ENOG41080HT	Transcriptional regulator, arsr family
HUK68_15705	ENOG4105C3J	Cysteine desulfurase
HUK68_15710	ENOG4108XM1	transcriptional regulator AsnC family
HUK68_15715	ENOG4107QHF	type ii secretion system protein e
HUK68_15730	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HUK68_15735	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HUK68_15740	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HUK68_15745	ENOG4105M6F	mutator MutT protein
HUK68_15755	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HUK68_15760	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HUK68_15775	ENOG4105KB2	stringent starvation protein b
HUK68_15780	ENOG4107MKT	Stringent starvation protein a
HUK68_15785	ENOG4105EIX	cytochrome c1
HUK68_15790	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HUK68_15795	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HUK68_15800	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HUK68_15805	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HUK68_15810	ENOG4107QNR	UPF0135 protein
HUK68_15820	ENOG4105C0H	protease
HUK68_15825	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HUK68_15830	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HUK68_15835	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HUK68_15840	ENOG4107YU2	histidine triad (hIT) protein
HUK68_15850	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HUK68_15855	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HUK68_15860	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HUK68_15865	ENOG4105CMR	udp-glucose 4-epimerase
HUK68_15875	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HUK68_15885	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HUK68_15890	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HUK68_15910	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HUK68_15915	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HUK68_15920	ENOG4105VFK	BolA family
HUK68_15925	ENOG4105E3A	(ABC) transporter
HUK68_15930	ENOG4105DA5	(ABC) transporter
HUK68_15945	ENOG410903C	(LipO)protein
HUK68_15950	ENOG4107PE3	Mammalian cell entry related domain protein
HUK68_15955	ENOG4105CY3	ABC transporter, permease
HUK68_15960	ENOG4105DHJ	ABC, transporter
HUK68_15965	ENOG4105CDA	abc transporter atp-binding protein
HUK68_15970	ENOG4105E5Q	amino acid AbC transporter
HUK68_15975	ENOG4105EAB	amino acid AbC transporter
HUK68_16010	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HUK68_16015	ENOG4105D49	3-dehydroquinate synthase
HUK68_16020	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HUK68_16030	ENOG4105E4G	Type IV pilus
HUK68_16055	ENOG4108JQC	penicillin-binding protein 1A
HUK68_16060	ENOG4105XQ6	frataxin-like protein
HUK68_16075	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HUK68_16080	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HUK68_16085	ENOG4105CRE	cytochrome C
HUK68_16090	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
HUK68_16095	ENOG4106RE7	Cytochrome
HUK68_16100	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HUK68_16105	ENOG4105D74	hydrolase
HUK68_16110	ENOG4105D1S	lipid A biosynthesis
HUK68_16120	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HUK68_16135	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HUK68_16160	ENOG4105E32	cytoplasmic protein
HUK68_16165	ENOG4105CQB	FAD linked oxidase domain protein
HUK68_16175	ENOG4105ETT	transcriptional Regulator, LysR family
HUK68_16190	ENOG4105WD1	Membrane
HUK68_16195	ENOG4105EGS	Mechanosensitive ion channel
HUK68_16200	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HUK68_16205	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HUK68_16210	ENOG4107QP8	phosphohexose isomerase
HUK68_16215	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HUK68_16230	ENOG4108Z9W	Outer membrane porin
HUK68_16235	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
HUK68_16240	ENOG4108UKZ	OsmC family
HUK68_16245	ENOG4105C7B	Threonine dehydratase
HUK68_16250	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HUK68_16265	ENOG4108VAU	general secretion pathway protein G
HUK68_16305	ENOG4105GVR	general secretion pathway protein D
HUK68_16310	ENOG4107QHF	type ii secretion system protein e
HUK68_16335	ENOG4105DEN	Luciferase family
HUK68_16340	ENOG4105D7Q	type ii secretion system
HUK68_16365	ENOG4105BZ1	(ABC) transporter
HUK68_16380	ENOG4108RH0	Crea protein
HUK68_16390	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HUK68_16395	ENOG4105CFG	Acts as a chaperone (By similarity)
HUK68_16465	ENOG41083UI	stage II sporulation protein
HUK68_16610	ENOG4105EMN	RNA polymerase sigma factor
HUK68_16630	ENOG4105BZU	Histidine kinase
HUK68_16665	ENOG4108TVJ	Nitroreductase
HUK68_16670	ENOG4108KTG	Membrane protein, drug metabolite transporter
HUK68_16675	ENOG4108ZT1	Transcriptional regulator
HUK68_16690	ENOG4105JSC	dimethylmenaquinone methyltransferase
HUK68_16695	ENOG4105DUM	transcriptional regulator, lysR family
HUK68_16710	ENOG4105BZU	Histidine kinase
HUK68_16720	ENOG4108XM1	transcriptional regulator AsnC family
HUK68_16725	ENOG4106F60	Histidine kinase
HUK68_16730	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HUK68_16735	ENOG4105ETT	transcriptional Regulator, LysR family
HUK68_16745	ENOG4105DR5	peptidase
HUK68_16750	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HUK68_16755	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HUK68_16760	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HUK68_16765	ENOG4108UJD	30S ribosomal protein S9
HUK68_16770	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HUK68_16775	ENOG4105D6S	protein involved in catabolism of external DNA
HUK68_16785	ENOG4105SYT	Methylenetetrahydrofolate reductase
HUK68_16790	ENOG4105DX0	Hemolysin A
HUK68_16795	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HUK68_16800	ENOG4105D94	Major Facilitator Superfamily
HUK68_16805	ENOG4105JZI	cytochrome P450
HUK68_16815	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HUK68_16825	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HUK68_16830	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HUK68_16835	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HUK68_16875	ENOG4108W5M	transcriptional regulator
HUK68_16885	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HUK68_16890	ENOG4108Z9W	Outer membrane porin
HUK68_16895	ENOG4105CSH	Transporter
HUK68_16910	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HUK68_16915	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HUK68_16925	ENOG4108IPT	Naphthoate synthase
HUK68_16930	ENOG4107QX3	carboxylase
HUK68_16935	ENOG4105EEQ	Na H antiporter
HUK68_16950	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HUK68_16955	ENOG4105K5B	UPF0225 protein
HUK68_16965	ENOG4105C1G	acyl-Coa dehydrogenase
HUK68_16970	ENOG4105EMU	Dehydrogenase
HUK68_16980	ENOG4105CHU	acetyl-coa acetyltransferase
HUK68_16985	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HUK68_16990	ENOG41077A9	carbonic anhydrase
HUK68_16995	ENOG4105C1G	acyl-Coa dehydrogenase
HUK68_17000	ENOG4108Z6Z	Transcriptional regulator
HUK68_17010	ENOG4105EHU	Circadian clock protein KaiC
HUK68_17145	ENOG4105C5H	ABC transporter
HUK68_17150	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HUK68_17155	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
HUK68_17160	ENOG4105BZU	Histidine kinase
HUK68_17165	ENOG4108V3W	Chemotaxis protein, CheW
HUK68_17170	ENOG4105CBS	Chea signal transduction histidine kinase
HUK68_17175	ENOG4108MGY	Histidine kinase
HUK68_17185	ENOG4105BZU	Histidine kinase
HUK68_17200	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HUK68_17205	ENOG4105VS8	Flagellar biosynthetic protein fliq
HUK68_17210	ENOG4105CN7	Flagellar biosynthetic protein FliP
HUK68_17215	ENOG4105K0P	flagellar biosynthesis protein
HUK68_17220	ENOG4105DD5	Flagellar motor switch protein
HUK68_17225	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HUK68_17230	ENOG4107ZI8	flagellar basal body-associated protein flil
HUK68_17245	ENOG4108JIR	Flagellum-specific ATP synthase
HUK68_17250	ENOG41090PJ	Flagellar assembly protein
HUK68_17255	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HUK68_17260	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HUK68_17275	ENOG4105MQ3	flagellar protein FliS
HUK68_17280	ENOG4105DTS	flagellar hook-associated
HUK68_17320	ENOG4107RD7	Flagellar Motor Protein, MotA
HUK68_17325	ENOG4105ER2	Ompa motb domain protein
HUK68_17330	ENOG4108VYJ	response regulator receiver protein
HUK68_17335	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HUK68_17340	ENOG4105D00	flagellar biosynthetic protein flhB
HUK68_17345	ENOG4105D7B	Flagellar biosynthesis protein flha
HUK68_17350	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HUK68_17360	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HUK68_17380	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HUK68_17385	ENOG4108ZC9	flagellar basal-body rod protein flgc
HUK68_17390	ENOG4105W00	Flagellar hook capping protein
HUK68_17395	ENOG4105BZE	flagellar hook protein, FlgE
HUK68_17400	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HUK68_17405	ENOG4105CGA	flagellar basal-body rod protein FlgG
HUK68_17410	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HUK68_17415	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HUK68_17420	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HUK68_17425	ENOG4105E1Q	flagellar hook-associated protein
HUK68_17430	ENOG4105DTJ	flagellar hook-associated protein
HUK68_17445	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HUK68_17450	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HUK68_17470	ENOG4107QJQ	Mate efflux family protein
HUK68_17490	ENOG4105D6U	Sodium Glutamate Symporter
HUK68_17495	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HUK68_17500	ENOG4105C25	Primosomal protein n'
HUK68_17510	ENOG4105RK9	auxin efflux carrier
HUK68_17515	ENOG4105C4R	Atp-dependent dna helicase
HUK68_17525	ENOG4105HDD	phospholipase
HUK68_17540	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HUK68_17545	ENOG4105BZU	Histidine kinase
HUK68_17575	ENOG4105IU3	Glutathione S-transferase
HUK68_17580	ENOG4107QYX	exodeoxyribonuclease v alpha
HUK68_17585	ENOG4107QKA	exodeoxyribonuclease V beta
HUK68_17590	ENOG4105DSY	exodeoxyribonuclease V, gamma
HUK68_17600	ENOG4105CHR	reductase
HUK68_17615	ENOG4108M0I	Transcriptional regulator
HUK68_17625	ENOG4105E39	Enoyl-CoA hydratase
HUK68_17635	ENOG4105CC9	acyl-Coa dehydrogenase
HUK68_17645	ENOG4105CHR	reductase
HUK68_17680	ENOG4105E5Q	amino acid AbC transporter
HUK68_17685	ENOG4105DRP	amino acid AbC transporter
HUK68_17690	ENOG4105CDA	abc transporter atp-binding protein
HUK68_17715	ENOG4105BZU	Histidine kinase
HUK68_17725	ENOG4105EGS	Mechanosensitive ion channel
HUK68_17740	ENOG4105ES5	Histidine kinase
HUK68_17750	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HUK68_17760	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HUK68_17765	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HUK68_17770	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HUK68_17775	ENOG4108VZM	50s ribosomal protein L10
HUK68_17780	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HUK68_17785	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HUK68_17795	ENOG4105PM1	preprotein translocase subunit SecE
HUK68_17805	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HUK68_17830	ENOG4107XI7	Tetr family transcriptional regulator
HUK68_17835	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HUK68_17840	ENOG4105BZS	acriflavin resistance protein
HUK68_17850	ENOG4105MPD	Cytochrome
HUK68_17880	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HUK68_17885	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HUK68_17890	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HUK68_17895	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HUK68_17900	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HUK68_17905	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HUK68_17910	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HUK68_17915	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
HUK68_17925	ENOG4108Z43	UPF0250 protein
HUK68_17930	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HUK68_17935	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HUK68_17940	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HUK68_17945	ENOG41080Z8	PHOSPHOCARRIER protein
HUK68_17955	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUK68_17970	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HUK68_17975	ENOG41084PQ	50s ribosomal protein l29
HUK68_17980	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HUK68_17985	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HUK68_17990	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HUK68_17995	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HUK68_18000	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUK68_18005	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HUK68_18010	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HUK68_18015	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HUK68_18020	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HUK68_18025	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HUK68_18030	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HUK68_18035	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HUK68_18040	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HUK68_18045	ENOG4105DZ1	carboxypeptidase
HUK68_18050	ENOG4105DHZ	alpha beta
HUK68_18055	ENOG4105NZG	Ferredoxin
HUK68_18070	ENOG4105D52	delta-aminolevulinic acid dehydratase
HUK68_18075	ENOG4105D7N	magnesium and cobalt transport protein CorA
HUK68_18085	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HUK68_18105	ENOG4105DHJ	ABC, transporter
HUK68_18125	ENOG4108HW3	(ABC) transporter
HUK68_18130	ENOG4105E5Q	amino acid AbC transporter
HUK68_18140	ENOG4105CJN	penicillin-binding protein
HUK68_18160	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HUK68_18165	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HUK68_18170	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HUK68_18205	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HUK68_18210	ENOG4105CGK	Exodeoxyribonuclease III
HUK68_18215	ENOG41090JD	Blue (Type 1) copper domain protein
HUK68_18230	ENOG4105E0F	Histidine kinase
HUK68_18250	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HUK68_18260	ENOG4105DZG	Dehydrogenase
HUK68_18275	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HUK68_18280	ENOG4108Z9W	Outer membrane porin
HUK68_18290	ENOG4105C5X	domain protein
HUK68_18305	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HUK68_18310	ENOG4105JJR	Histidine kinase
HUK68_18330	ENOG4107T8Q	Glycosyl transferase (Group 1
HUK68_18340	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HUK68_18350	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HUK68_18365	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HUK68_18385	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HUK68_18390	ENOG4105EU8	FAD linked oxidase domain protein
HUK68_18395	ENOG4105BZU	Histidine kinase
HUK68_18400	ENOG4108YZA	Nitrogen regulatory protein pii
HUK68_18420	ENOG4105JSC	dimethylmenaquinone methyltransferase
HUK68_18425	ENOG4108JQ1	Dehydrogenase
HUK68_18440	ENOG4105GAK	amidohydrolase 2
HUK68_18455	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_18470	ENOG4108UQ8	endoribonuclease L-psp
HUK68_18480	ENOG4105C0P	Mg chelatase subunit ChlI
HUK68_18490	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HUK68_18495	ENOG4107SMJ	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
HUK68_18540	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HUK68_18565	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HUK68_18600	ENOG4105C0P	Mg chelatase subunit ChlI
HUK68_18610	ENOG4105E9F	Enoyl-CoA hydratase
HUK68_18625	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HUK68_18640	ENOG4108IV0	ABC, transporter
HUK68_18645	ENOG4105C0Z	ABC transporter
HUK68_18650	ENOG4105C32	Amino acid ABC transporter (Permease)
HUK68_18655	ENOG41083Z3	extracellular ligand-binding receptor
HUK68_18660	ENOG4105DP0	ferredoxin-NADP reductase
HUK68_18670	ENOG4105C5I	Dehydrogenase
HUK68_18675	ENOG4105C3R	Methionine synthase
HUK68_18680	ENOG4105C26	Dehydrogenase
HUK68_18685	ENOG4105EQ2	LysR family Transcriptional regulator
HUK68_18690	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HUK68_18700	ENOG4105DH8	myo-inositol catabolism
HUK68_18705	ENOG4105D7K	pfkb domain protein
HUK68_18730	ENOG4105D82	Glutamate dehydrogenase
HUK68_18745	ENOG4105C3R	Methionine synthase
HUK68_18750	ENOG4105CF1	Alkylated DNA repair protein
HUK68_18755	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HUK68_18760	ENOG4105CSU	acyl-Coa dehydrogenase
HUK68_18765	ENOG4105CSU	acyl-Coa dehydrogenase
HUK68_18770	ENOG4105C7B	Threonine dehydratase
HUK68_18780	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
HUK68_18830	ENOG4105DVT	helicase
HUK68_18840	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HUK68_18845	ENOG4107QMS	site-determining protein
HUK68_18850	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HUK68_18855	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HUK68_18860	ENOG4105C2W	permease
HUK68_18875	ENOG4105KA0	thioesterase Superfamily protein
HUK68_18880	ENOG4105F04	LysR family Transcriptional regulator
HUK68_18895	ENOG4108WBT	adenosyltransferase
HUK68_18900	ENOG4105CQB	FAD linked oxidase domain protein
HUK68_18925	ENOG4105HEI	LysR family (Transcriptional regulator
HUK68_18930	ENOG4105F27	Major Facilitator
HUK68_18935	ENOG4105CH7	arginosuccinase
HUK68_18940	ENOG4105CH7	arginosuccinase
HUK68_18945	ENOG4105FA0	parb-like partition protein
HUK68_18955	ENOG4107QJE	Chromosome Partitioning Protein
HUK68_18960	ENOG4108NIW	Leucine export protein LeuE
HUK68_18965	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HUK68_18970	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HUK68_18975	ENOG4108K3A	Glutathione S-transferase
HUK68_18980	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HUK68_18985	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_19010	ENOG4105C0Z	ABC transporter
HUK68_19030	ENOG4108IV0	ABC, transporter
HUK68_19035	ENOG4108IQE	Amp-dependent synthetase and ligase
HUK68_19040	ENOG4105CHU	acetyl-coa acetyltransferase
HUK68_19045	ENOG4105DH7	May be involved in recombination (By similarity)
HUK68_19055	ENOG41061N2	exported protein
HUK68_19065	ENOG4105DVT	helicase
HUK68_19070	ENOG4105BZU	Histidine kinase
HUK68_19080	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HUK68_19090	ENOG4108ZCF	integral membrane protein
HUK68_19095	ENOG4107T7U	Sulfatase
HUK68_19105	ENOG41084CK	capsule polysaccharide
HUK68_19110	ENOG4105E12	capsule polysaccharide
HUK68_19125	ENOG4107T8Q	Glycosyl transferase (Group 1
HUK68_19130	ENOG4108DMA	Nad-dependent epimerase dehydratase
HUK68_19135	ENOG4106ECQ	phosphomannomutase
HUK68_19140	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
HUK68_19150	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HUK68_19170	ENOG4105EY8	ABC transporter
HUK68_19190	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
HUK68_19195	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HUK68_19200	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HUK68_19205	ENOG4108XHQ	(2Fe-2S)-binding domain protein
HUK68_19210	ENOG4108JU7	Transcriptional regulator
HUK68_19225	ENOG4105BZU	Histidine kinase
HUK68_19235	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HUK68_19240	ENOG4105D7T	ABC transporter
HUK68_19250	ENOG4105DRR	Transcriptional regulator, GntR family
HUK68_19270	ENOG4105EQ2	LysR family Transcriptional regulator
HUK68_19280	ENOG4105E2Y	ABC, transporter
HUK68_19285	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HUK68_19290	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
HUK68_19320	ENOG4105D94	Major Facilitator Superfamily
HUK68_19325	ENOG4107RSM	transcriptional regulator
HUK68_19340	ENOG4107SDU	Methyl-accepting chemotaxis
HUK68_19345	ENOG4105BZU	Histidine kinase
HUK68_19350	ENOG4105BZU	Histidine kinase
HUK68_19355	ENOG4108YAB	Invasion protein
HUK68_19370	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HUK68_19380	ENOG4108MAJ	Membrane
HUK68_19410	ENOG4105J12	Multidrug resistance protein mdtN
HUK68_19425	ENOG4105E0Y	RtcB Protein
HUK68_19435	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HUK68_19440	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HUK68_19450	ENOG4107QJE	Chromosome Partitioning Protein
HUK68_19535	ENOG4105CV8	reductase
HUK68_19540	ENOG4105HEI	LysR family (Transcriptional regulator
HUK68_19570	ENOG4108D1Y	Polypeptide-transport-associated domain protein, ShlB-type
HUK68_19620	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HUK68_19645	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HUK68_19650	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
HUK68_19665	ENOG4105C5I	Dehydrogenase
HUK68_19675	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HUK68_19690	ENOG4105CHR	reductase
HUK68_19695	ENOG4105CBN	LysR family transcriptional regulator
HUK68_19710	ENOG4105EQ2	LysR family Transcriptional regulator
HUK68_19720	ENOG4105C5Q	Transcriptional regulator
HUK68_19730	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HUK68_19745	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HUK68_19750	ENOG4105J5J	Outer membrane porin
HUK68_19760	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HUK68_19765	ENOG4105EHG	Permease protein
HUK68_19780	ENOG4107QRP	cobalamin biosynthesis protein CobW
HUK68_19785	ENOG4105CTK	cobaltochelatase, cobn subunit
HUK68_19800	ENOG4105DZG	Dehydrogenase
HUK68_19805	ENOG4105E0K	tonB-dependent siderophore receptor
HUK68_19810	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HUK68_19820	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_19830	ENOG4105C10	Electron transfer flavoprotein
HUK68_19835	ENOG4105BZJ	Electron transfer flavoprotein
HUK68_19845	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_19850	ENOG4108UKI	Enoyl-CoA hydratase
HUK68_19855	ENOG4105C1G	acyl-Coa dehydrogenase
HUK68_19860	ENOG4105CC9	acyl-Coa dehydrogenase
HUK68_19865	ENOG4105CHU	acetyl-coa acetyltransferase
HUK68_19870	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HUK68_19875	ENOG4105CBN	LysR family transcriptional regulator
HUK68_19890	ENOG4108IG5	Transcriptional regulator
HUK68_19895	ENOG4105C2C	drug resistance transporter, Bcr CflA
HUK68_19900	ENOG4107DA6	Transcriptional regulator
HUK68_19910	ENOG4105CW7	secretion protein, HlyD family
HUK68_19915	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HUK68_19920	ENOG4105BZ1	(ABC) transporter
HUK68_19940	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HUK68_19985	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_20015	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HUK68_20035	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HUK68_20045	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HUK68_20050	ENOG4106P55	Transcriptional regulator
HUK68_20080	ENOG4105C2C	drug resistance transporter, Bcr CflA
HUK68_20115	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HUK68_20130	ENOG4105CYM	Glutathione S-transferase
HUK68_20140	ENOG4105CQB	FAD linked oxidase domain protein
HUK68_20155	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HUK68_20165	ENOG4105E89	ABC transporter
HUK68_20175	ENOG4105DRP	amino acid AbC transporter
HUK68_20180	ENOG4105E5Q	amino acid AbC transporter
HUK68_20185	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HUK68_20195	ENOG4105BZU	Histidine kinase
HUK68_20205	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
HUK68_20240	ENOG4105CD5	CoA-binding domain protein
HUK68_20255	ENOG4105CC9	acyl-Coa dehydrogenase
HUK68_20260	ENOG4107SJW	iron permease, FTR1
HUK68_20265	ENOG4105CMQ	Chloride channel
HUK68_20270	ENOG4105BZU	Histidine kinase
HUK68_20280	ENOG4105BZU	Histidine kinase
HUK68_20285	ENOG4105EYH	Exonuclease
HUK68_20290	ENOG4107RH8	nuclease SbcCD subunit D
HUK68_20305	ENOG4108PCN	EamA-like transporter family
HUK68_20330	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
HUK68_20340	ENOG4105EGI	Transcriptional regulator
HUK68_20350	ENOG4105EU0	Major facilitator Superfamily
HUK68_20365	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HUK68_20370	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HUK68_20375	ENOG4105C7W	Xanthine dehydrogenase
HUK68_20380	ENOG4105DKB	L-sorbosone dehydrogenase
HUK68_20385	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HUK68_20395	ENOG4107GJV	short-chain dehydrogenase reductase
HUK68_20405	ENOG4105DTR	rard protein
HUK68_20415	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HUK68_20425	ENOG4105DQE	DNA ligase
HUK68_20445	ENOG4105C26	Dehydrogenase
HUK68_20450	ENOG4108VX5	3-methyladenine DNA glycosylase
HUK68_20455	ENOG4108JU3	Alkyl hydroperoxide reductase
HUK68_20470	ENOG4107RTG	Major Facilitator superfamily
HUK68_20475	ENOG4105ENX	hydrolase
HUK68_20480	ENOG4105EQ2	LysR family Transcriptional regulator
HUK68_20505	ENOG4105C0B	DNA polymerase III (alpha subunit)
HUK68_20545	ENOG4105EW6	flavin reductase domain protein, FMN-binding
HUK68_20550	ENOG41061H0	Monooxygenase
HUK68_20555	ENOG4105CBN	LysR family transcriptional regulator
HUK68_20570	ENOG4105K5X	acetyltransferase
HUK68_20585	ENOG4105EQ2	LysR family Transcriptional regulator
HUK68_20590	ENOG4107RSM	transcriptional regulator
HUK68_20600	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_20615	ENOG4105CGU	Enoyl-CoA hydratase
HUK68_20625	ENOG4107S9F	NmrA family
HUK68_20670	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HUK68_20675	ENOG41067SE	Tetr family transcriptional regulator
HUK68_20705	ENOG4105CHR	reductase
HUK68_20710	ENOG4105CC9	acyl-Coa dehydrogenase
HUK68_20730	ENOG4107S2E	monooxygenase
HUK68_20735	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HUK68_20745	ENOG4105C32	Amino acid ABC transporter (Permease)
HUK68_20750	ENOG4108IV0	ABC, transporter
HUK68_20755	ENOG4105C0Z	ABC transporter
HUK68_20780	ENOG4105E39	Enoyl-CoA hydratase
HUK68_20790	ENOG4108Z9W	Outer membrane porin
HUK68_20830	ENOG41079KZ	Major Facilitator Superfamily
HUK68_20835	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HUK68_20860	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_20870	ENOG4107QWB	Ornithine cyclodeaminase
HUK68_20885	ENOG4105CC0	LysR family Transcriptional regulator
HUK68_20890	ENOG4105W1Y	Transcriptional regulator
HUK68_20900	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HUK68_20910	ENOG4105W7K	Transcriptional regulator
HUK68_20920	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HUK68_20930	ENOG4108S3W	Anti-feci sigma factor, fecr
HUK68_20935	ENOG4108SF5	RNA Polymerase
HUK68_20950	ENOG4107SQD	Transcriptional regulator, GntR family
HUK68_20980	ENOG4105BZU	Histidine kinase
HUK68_20990	ENOG4107QRT	dEAD DEAH box helicase
HUK68_20995	ENOG4107T0X	DNA ligase
HUK68_21000	ENOG4107T0X	DNA ligase
HUK68_21005	ENOG4105DQ4	alcohol dehydrogenase
HUK68_21010	ENOG4105BZU	Histidine kinase
HUK68_21015	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HUK68_21035	ENOG4105MVE	transcriptional regulator
HUK68_21045	ENOG4105G63	Type III effector Hrp-dependent
HUK68_21050	ENOG4105FB2	class II Aldolase
HUK68_21055	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HUK68_21060	ENOG4105CZQ	inner membrane transport protein YdhC
HUK68_21070	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HUK68_21075	ENOG4108Z9W	Outer membrane porin
HUK68_21080	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HUK68_21085	ENOG4105C4Y	ABC transporter
HUK68_21095	ENOG41060I7	thioesterase Superfamily protein
HUK68_21100	ENOG4105CSR	polyphosphate kinase 2
HUK68_21145	ENOG4108JU7	Transcriptional regulator
HUK68_21155	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HUK68_21160	ENOG4105E39	Enoyl-CoA hydratase
HUK68_21175	ENOG4105GZI	Transcriptional regulator
HUK68_21180	ENOG4105IJY	hydroxylase
HUK68_21200	ENOG41087PP	glycosyltransferase MGT family
HUK68_21205	ENOG4108UK3	Polyprenyl synthetase
HUK68_21210	ENOG4105C7K	acetolactate synthase
HUK68_21220	ENOG4108Z0Z	intracellular protease Pfpi family
HUK68_21230	ENOG4105C1G	acyl-Coa dehydrogenase
HUK68_21235	ENOG4105CEY	Amp-dependent synthetase and ligase
HUK68_21245	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HUK68_21250	ENOG4108YYH	Nadph-dependent fmn reductase
HUK68_21255	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HUK68_21265	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
HUK68_21270	ENOG41084HI	prevent-host-death family
HUK68_21300	ENOG4105DFS	Conserved Protein
HUK68_21350	ENOG4107QPK	)-transporter
HUK68_21355	ENOG4105D0C	transport protein
HUK68_21375	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HUK68_21390	ENOG4105D5T	phosphonate abc transporter
HUK68_21395	ENOG4107T9Q	phosphonate abc transporter
HUK68_21405	ENOG4105HSS	phospholipase C
HUK68_21430	ENOG4105D7T	ABC transporter
HUK68_21450	ENOG4105CNM	Receptor
HUK68_21470	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_21510	ENOG4105E0K	tonB-dependent siderophore receptor
HUK68_21520	ENOG4105EHG	Permease protein
HUK68_21525	ENOG4105E0A	ABC, transporter
HUK68_21540	ENOG4105CBC	glutamate synthase
HUK68_21550	ENOG41067SE	Tetr family transcriptional regulator
HUK68_21555	ENOG4105C26	Dehydrogenase
HUK68_21560	ENOG4105EW9	transcriptional regulator AsnC family
HUK68_21570	ENOG4105MP9	class II Aldolase
HUK68_21580	ENOG4105C5I	Dehydrogenase
HUK68_21585	ENOG4105EQ2	LysR family Transcriptional regulator
HUK68_21595	ENOG4107EFR	Flavocytochrome c
HUK68_21600	ENOG41079YP	Citrate utilization protein b
HUK68_21630	ENOG4105C0Z	ABC transporter
HUK68_21635	ENOG4108IV0	ABC, transporter
HUK68_21640	ENOG4105C8Q	Methyl-accepting chemotaxis
HUK68_21645	ENOG4105II7	pyrroline-5-carboxylate reductase
HUK68_21655	ENOG4105BZN	citrate synthase
HUK68_21660	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
HUK68_21665	ENOG4105DSE	periplasmic solute binding protein
HUK68_21670	ENOG4105CC5	ABC transporter
HUK68_21675	ENOG4105DIK	(ABC) transporter
HUK68_21695	ENOG4105CQZ	Histidine kinase
HUK68_21700	ENOG4108Z9Z	response to DNA damage stimulus
HUK68_21705	ENOG4105CPC	Aldo Keto reductase
HUK68_21715	ENOG4105CSP	Major Facilitator Superfamily
HUK68_21720	ENOG4106517	Short-chain dehydrogenase reductase Sdr
HUK68_21730	ENOG4105DDW	LysR family Transcriptional regulator
HUK68_21735	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HUK68_21740	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HUK68_21745	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HUK68_21750	ENOG4105DC8	reductase
HUK68_21770	ENOG4107QM5	aconitate hydratase
HUK68_21775	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HUK68_21785	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HUK68_21790	ENOG4105ETT	transcriptional Regulator, LysR family
HUK68_21800	ENOG4105DXI	Major Facilitator superfamily
HUK68_21805	ENOG4105P69	integral membrane protein
HUK68_21810	ENOG4105C7K	acetolactate synthase
HUK68_21825	ENOG4105C5Q	Transcriptional regulator
HUK68_21835	ENOG4108SF5	RNA Polymerase
HUK68_21840	ENOG4108S3W	Anti-feci sigma factor, fecr
HUK68_21875	ENOG4105UPE	Enoyl-CoA hydratase
HUK68_21885	ENOG4105D2B	acyl-CoA dehydrogenase
HUK68_21890	ENOG4105EA8	2-Nitropropane dioxygenase
HUK68_21905	ENOG4105CHR	reductase
HUK68_21910	ENOG4105CHU	acetyl-coa acetyltransferase
HUK68_21935	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HUK68_21940	ENOG4105E39	Enoyl-CoA hydratase
HUK68_21945	ENOG4106NZI	LysR family Transcriptional regulator
HUK68_21955	ENOG4105ERH	Fumarylacetoacetate hydrolase
HUK68_22005	ENOG4108VMM	UPF0756 membrane protein
HUK68_22010	ENOG4105CVR	type I restriction-modification system
HUK68_22025	ENOG4105E1J	oxidoreductase
HUK68_22050	ENOG41082CG	Protein CrcB homolog
HUK68_22055	ENOG4108R96	Methyltransferase, YaeB family
HUK68_22060	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HUK68_22065	ENOG4105E0C	molybdate abc transporter
HUK68_22070	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HUK68_22080	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HUK68_22085	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HUK68_22100	ENOG4105C08	Histidine kinase
HUK68_22105	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HUK68_22110	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HUK68_22115	ENOG4105QNF	Outer membrane lipoprotein
HUK68_22125	ENOG4105RPH	Inner membrane protein YddG
HUK68_22140	ENOG4106NZI	LysR family Transcriptional regulator
HUK68_22165	ENOG4105EIG	urea carboxylase-associated protein 1
HUK68_22185	ENOG4105BZU	Histidine kinase
HUK68_22225	ENOG4105WH9	RNA polymerase
HUK68_22230	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HUK68_22235	ENOG4105JQN	Transcriptional regulator
HUK68_22250	ENOG4107QJE	Chromosome Partitioning Protein
HUK68_22305	ENOG4105CMA	conjugation trbi family protein
HUK68_22360	ENOG4108UB3	Thiamine monophosphate
HUK68_22370	ENOG4105D7V	transposase
HUK68_22375	ENOG4106H6R	UPF0380 protein
HUK68_22395	ENOG4105KT5	UmuD protein
HUK68_22400	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HUK68_22425	ENOG4108M0I	Transcriptional regulator
HUK68_22485	ENOG4105D5G	Transposase
HUK68_22495	ENOG4105CNM	Receptor
HUK68_22520	ENOG4108JQ1	Dehydrogenase
HUK68_22525	ENOG4105JSC	dimethylmenaquinone methyltransferase
HUK68_22535	ENOG4105DDW	LysR family Transcriptional regulator
HUK68_22585	ENOG4105E2A	Dehydrogenase
HUK68_22610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HUK68_22615	ENOG4105MP0	transposase
HUK68_22625	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
HUK68_22630	ENOG4105E5H	Transposase
HUK68_22645	ENOG4105BZU	Histidine kinase
HUK68_22650	ENOG4108F09	Urease subunit gamma beta
HUK68_22655	ENOG4105CQM	Urea amidohydrolase subunit alpha
HUK68_22660	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HUK68_22665	ENOG4108XNJ	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HUK68_22685	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HUK68_22700	ENOG4105C32	Amino acid ABC transporter (Permease)
HUK68_22705	ENOG4105C0Z	ABC transporter
HUK68_22710	ENOG4108IV0	ABC, transporter
HUK68_22720	ENOG4105QPS	Monooxygenase
HUK68_22730	ENOG4105M4H	endoribonuclease L-psp
HUK68_22760	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HUK68_22765	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HUK68_22770	ENOG4105EW9	transcriptional regulator AsnC family
HUK68_22790	ENOG4105EJQ	L-serine dehydratase
HUK68_22795	ENOG4105DND	Transcriptional regulator
HUK68_22805	ENOG4105JSC	dimethylmenaquinone methyltransferase
HUK68_22830	ENOG4105KPV	Transcriptional regulator
HUK68_22895	ENOG4108IJF	Heavy metal efflux pump, CzcA
HUK68_22900	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
HUK68_22925	ENOG4105GR3	Histidine kinase
HUK68_22980	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HUK68_22995	ENOG4105CAU	Arsenical resistance protein, ArsH
HUK68_23000	ENOG4105K89	arsenate reductase
HUK68_23040	ENOG4105EYK	Phosphatidylglycerophosphatase B
HUK68_23050	ENOG4105W1Y	Transcriptional regulator
HUK68_23080	ENOG4105VT3	DNA binding domain protein, excisionase family
HUK68_23125	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS