locus-tag	class	description
EAG14_00085	COG4969	Belongs to the N-Me-Phe pilin family
EAG14_00090	COG4969	Belongs to the N-Me-Phe pilin family
EAG14_00105	COG0315	cyclic pyranopterin monophosphate synthase activity
EAG14_00115	COG1950	PFAM Membrane protein of
EAG14_00125	COG0861	Integral membrane protein TerC family
EAG14_00130	COG0861	Integral membrane protein TerC family
EAG14_00145	COG4681	YaeQ
EAG14_00155	COG0625	glutathione transferase activity
EAG14_00160	COG1309	transcriptional regulator
EAG14_00165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EAG14_00170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAG14_00175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_00180	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EAG14_00190	COG0300	oxidoreductase activity
EAG14_00210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EAG14_00255	COG0840	transmembrane signaling receptor activity
EAG14_00270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAG14_00320	COG2814	Major facilitator Superfamily
EAG14_00325	COG1522	sequence-specific DNA binding
EAG14_00335	COG1862	Preprotein translocase
EAG14_00340	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAG14_00345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAG14_00355	COG0758	DNA mediated transformation
EAG14_00365	COG0242	peptide deformylase activity
EAG14_00375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EAG14_00390	COG0126	phosphoglycerate kinase activity
EAG14_00400	COG0284	orotidine-5'-phosphate decarboxylase activity
EAG14_00405	COG0583	DNA-binding transcription factor activity
EAG14_00430	COG1454	alcohol dehydrogenase
EAG14_00435	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_00440	COG3284	Transcriptional regulator
EAG14_00445	COG2205	protein histidine kinase activity
EAG14_00450	COG0745	RESPONSE REGULATOR receiver
EAG14_00470	COG2207	Transcriptional regulator
EAG14_00480	COG2814	Major facilitator Superfamily
EAG14_00485	COG0629	single-stranded DNA binding
EAG14_00490	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EAG14_00500	COG3831	ATPase activity
EAG14_00515	COG0714	Associated with various cellular activities
EAG14_00525	COG0482	sulfurtransferase activity
EAG14_00530	COG0840	transmembrane signaling receptor activity
EAG14_00540	COG1053	succinate dehydrogenase
EAG14_00550	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_00565	COG0583	DNA-binding transcription factor activity
EAG14_00585	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EAG14_00615	COG2267	carboxylic ester hydrolase activity
EAG14_00625	COG3706	GGDEF domain
EAG14_00625	COG0745	RESPONSE REGULATOR receiver
EAG14_00630	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAG14_00635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAG14_00635	COG2813	Specifically methylates the guanine in position
EAG14_00640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAG14_00645	COG2119	membrane
EAG14_00650	COG0724	RNA recognition motif
EAG14_00655	COG0724	RNA recognition motif
EAG14_00670	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EAG14_00675	COG0517	IMP dehydrogenase activity
EAG14_00675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EAG14_00690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EAG14_00695	COG4175	Glycine betaine
EAG14_00700	COG4176	ABC-type proline glycine betaine transport system permease component
EAG14_00705	COG2113	Glycine betaine
EAG14_00735	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EAG14_00740	COG0784	Response regulator, receiver
EAG14_00740	COG2205	protein histidine kinase activity
EAG14_00740	COG2198	Histidine kinase
EAG14_00745	COG3437	response regulator, receiver
EAG14_00790	COG0583	DNA-binding transcription factor activity
EAG14_00795	COG0667	Aldo Keto reductase
EAG14_00855	COG0584	glycerophosphoryl diester phosphodiesterase
EAG14_00860	COG0840	transmembrane signaling receptor activity
EAG14_00890	COG0346	lactoylglutathione lyase activity
EAG14_00895	COG3550	peptidyl-serine autophosphorylation
EAG14_00920	COG0419	ATPase involved in DNA repair
EAG14_00925	COG0420	3'-5' exonuclease activity
EAG14_00945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_00950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAG14_00985	COG0840	transmembrane signaling receptor activity
EAG14_00995	COG0583	DNA-binding transcription factor activity
EAG14_01000	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_01015	COG2378	regulation of single-species biofilm formation
EAG14_01070	COG0625	glutathione transferase activity
EAG14_01110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EAG14_01125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EAG14_01125	COG1648	precorrin-2 dehydrogenase activity
EAG14_01130	COG2010	Cytochrome c
EAG14_01135	COG3391	amine dehydrogenase activity
EAG14_01200	COG0410	ABC transporter
EAG14_01215	COG0583	DNA-binding transcription factor activity
EAG14_01230	COG2159	amidohydrolase
EAG14_01280	COG0667	Aldo Keto reductase
EAG14_01285	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAG14_01290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAG14_01295	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EAG14_01300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EAG14_01310	COG0006	proline dipeptidase activity
EAG14_01320	COG0671	phosphoesterase, PA-phosphatase related
EAG14_01330	COG0745	RESPONSE REGULATOR receiver
EAG14_01335	COG0642	Histidine kinase
EAG14_01345	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EAG14_01360	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EAG14_01365	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EAG14_01370	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_01375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAG14_01380	COG0598	Magnesium transport protein CorA
EAG14_01395	COG1214	PFAM Peptidase M22, glycoprotease
EAG14_01400	COG0840	transmembrane signaling receptor activity
EAG14_01435	COG0009	L-threonylcarbamoyladenylate synthase
EAG14_01440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EAG14_01450	COG3118	belongs to the thioredoxin family
EAG14_01455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EAG14_01465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAG14_01475	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EAG14_01480	COG0735	belongs to the Fur family
EAG14_01485	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAG14_01505	COG0495	leucyl-tRNA aminoacylation
EAG14_01515	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EAG14_01545	COG0601	transmembrane transport
EAG14_01560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAG14_01570	COG0840	transmembrane signaling receptor activity
EAG14_01590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EAG14_01595	COG0569	domain protein
EAG14_01600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAG14_01610	COG3158	transport of potassium into the cell
EAG14_01615	COG3135	benzoate transporter
EAG14_01620	COG0189	ligase activity
EAG14_01650	COG0121	glutamine amidotransferase
EAG14_01660	COG1942	4-Oxalocrotonate Tautomerase
EAG14_01675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EAG14_01700	COG1301	dicarboxylic acid transport
EAG14_01715	COG0018	arginyl-trna synthetase
EAG14_01725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAG14_01735	COG1137	ATPase activity
EAG14_01770	COG0069	glutamate synthase activity
EAG14_01780	COG0659	secondary active sulfate transmembrane transporter activity
EAG14_01810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_01820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EAG14_01840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_01850	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EAG14_01865	COG2967	ApaG domain
EAG14_01870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAG14_01900	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_01905	COG0583	DNA-binding transcription factor activity
EAG14_01910	COG0546	phosphoglycolate phosphatase activity
EAG14_01930	COG0512	Glutamine amidotransferase of anthranilate synthase
EAG14_01935	COG1280	lysine exporter protein (LysE YggA)
EAG14_01940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAG14_01950	COG0134	indole-3-glycerol-phosphate synthase activity
EAG14_01955	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EAG14_01960	COG2885	chlorophyll binding
EAG14_02005	COG0783	Belongs to the Dps family
EAG14_02010	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EAG14_02050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EAG14_02065	COG3842	ATPase activity
EAG14_02080	COG0395	ABC-type sugar transport system, permease component
EAG14_02095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EAG14_02100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EAG14_02105	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EAG14_02110	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EAG14_02115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EAG14_02120	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EAG14_02125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EAG14_02130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EAG14_02135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EAG14_02140	COG1841	ribosomal large subunit assembly
EAG14_02145	COG0200	Binds to the 23S rRNA
EAG14_02150	COG0201	protein transport
EAG14_02155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EAG14_02160	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EAG14_02165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EAG14_02170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EAG14_02175	COG0202	RNA polymerase activity
EAG14_02180	COG0203	ribosomal protein L17
EAG14_02190	COG0583	DNA-binding transcription factor activity
EAG14_02225	COG2847	Copper chaperone PCu(A)C
EAG14_02280	COG0204	Acyl-transferase
EAG14_02280	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_02295	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EAG14_02360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAG14_02380	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_02385	COG1090	epimerase
EAG14_02395	COG3706	GGDEF domain
EAG14_02400	COG0343	queuine tRNA-ribosyltransferase activity
EAG14_02425	COG0210	DNA helicase
EAG14_02460	COG0405	Gamma-glutamyltransferase
EAG14_02470	COG2382	esterase
EAG14_02485	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EAG14_02490	COG2814	Major facilitator Superfamily
EAG14_02495	COG0583	DNA-binding transcription factor activity
EAG14_02500	COG0861	Integral membrane protein TerC family
EAG14_02510	COG1832	CoA-binding protein
EAG14_02535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EAG14_02575	COG1280	lysine exporter protein (LysE YggA)
EAG14_02585	COG0384	phenazine biosynthesis protein PhzF
EAG14_02595	COG0625	glutathione transferase activity
EAG14_02600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_02620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_02650	COG4191	Histidine kinase
EAG14_02655	COG4566	intracellular signal transduction
EAG14_02660	COG4566	intracellular signal transduction
EAG14_02665	COG2910	NAD(P)H-binding
EAG14_02670	COG0583	DNA-binding transcription factor activity
EAG14_02695	COG1706	bacterial-type flagellum-dependent cell motility
EAG14_02705	COG4786	Flagellar basal body rod
EAG14_02710	COG4787	bacterial-type flagellum-dependent cell motility
EAG14_02720	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EAG14_02725	COG1558	bacterial-type flagellum-dependent cell motility
EAG14_02730	COG1815	bacterial-type flagellum-dependent cell motility
EAG14_02750	COG1191	sigma factor activity
EAG14_02765	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAG14_02775	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EAG14_02780	COG0745	RESPONSE REGULATOR receiver
EAG14_02785	COG1360	Flagellar Motor Protein
EAG14_02845	COG1516	flagellar protein fliS
EAG14_02855	COG1677	Flagellar hook-basal body complex protein FliE
EAG14_02890	COG1580	Controls the rotational direction of flagella during chemotaxis
EAG14_02910	COG1338	Plays a role in the flagellum-specific transport system
EAG14_02915	COG1987	bacterial-type flagellum assembly
EAG14_02925	COG2197	response regulator
EAG14_02940	COG2201	protein-glutamate methylesterase activity
EAG14_02950	COG0835	chemotaxis
EAG14_02955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EAG14_02960	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EAG14_02965	COG2201	protein-glutamate methylesterase activity
EAG14_03010	COG1960	acyl-CoA dehydrogenase activity
EAG14_03020	COG0288	reversible hydration of carbon dioxide
EAG14_03025	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EAG14_03030	COG0183	Belongs to the thiolase family
EAG14_03045	COG0300	oxidoreductase activity
EAG14_03050	COG1960	acyl-CoA dehydrogenase activity
EAG14_03055	COG2323	membrane
EAG14_03065	COG3012	SEC-C Motif Domain Protein
EAG14_03075	COG1994	Peptidase M50
EAG14_03080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAG14_03105	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_03110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EAG14_03120	COG0823	Involved in the tonB-independent uptake of proteins
EAG14_03120	COG1506	peptidase
EAG14_03130	COG1024	Enoyl-CoA hydratase
EAG14_03145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAG14_03150	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_03155	COG3246	L-lysine catabolic process to acetate
EAG14_03160	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_03165	COG0583	DNA-binding transcription factor activity
EAG14_03205	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAG14_03220	COG0683	leucine binding
EAG14_03225	COG0683	leucine binding
EAG14_03230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EAG14_03255	COG2423	ornithine cyclodeaminase activity
EAG14_03300	COG4154	Belongs to the RbsD FucU family
EAG14_03340	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EAG14_03355	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAG14_03360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EAG14_03370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EAG14_03375	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EAG14_03390	COG0316	Belongs to the HesB IscA family
EAG14_03395	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EAG14_03400	COG0739	heme binding
EAG14_03410	COG3706	GGDEF domain
EAG14_03410	COG0745	RESPONSE REGULATOR receiver
EAG14_03415	COG0583	DNA-binding transcription factor activity
EAG14_03425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EAG14_03430	COG2205	protein histidine kinase activity
EAG14_03435	COG1522	sequence-specific DNA binding
EAG14_03440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EAG14_03455	COG2186	Transcriptional regulator
EAG14_03460	COG4948	Mandelate Racemase Muconate Lactonizing
EAG14_03470	COG0601	transmembrane transport
EAG14_03480	COG0444	Belongs to the ABC transporter superfamily
EAG14_03485	COG4608	Belongs to the ABC transporter superfamily
EAG14_03495	COG2151	metal-sulfur cluster biosynthetic enzyme
EAG14_03510	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_03525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAG14_03530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAG14_03555	COG3386	PFAM SMP-30 Gluconolaconase
EAG14_03565	COG2011	ABC-type metal ion transport system permease component
EAG14_03580	COG1464	Belongs to the NlpA lipoprotein family
EAG14_03590	COG1960	acyl-CoA dehydrogenase activity
EAG14_03610	COG1965	Belongs to the frataxin family
EAG14_03645	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EAG14_03670	COG0069	glutamate synthase activity
EAG14_03670	COG0067	glutamate synthase
EAG14_03670	COG0070	glutamate synthase
EAG14_03680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_03685	COG0765	amino acid transport
EAG14_03695	COG1127	ABC transporter
EAG14_03700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EAG14_03705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAG14_03710	COG2853	Lipoprotein
EAG14_03725	COG1131	(ABC) transporter
EAG14_03730	COG0842	Transport permease protein
EAG14_03735	COG5007	Belongs to the BolA IbaG family
EAG14_03740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EAG14_03745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EAG14_03760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_03770	COG4948	Mandelate Racemase Muconate Lactonizing
EAG14_03775	COG0800	Aldolase
EAG14_03780	COG3734	2-keto-3-deoxy-galactonokinase
EAG14_03795	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAG14_03800	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAG14_03805	COG1129	ABC transporter
EAG14_03810	COG4214	carbohydrate transport
EAG14_03820	COG4213	ABC transporter substrate-binding protein
EAG14_03825	COG1879	ABC-type sugar transport system periplasmic component
EAG14_03830	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_03840	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_03845	COG3386	PFAM SMP-30 Gluconolaconase
EAG14_03850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EAG14_03855	COG0745	RESPONSE REGULATOR receiver
EAG14_03860	COG2205	protein histidine kinase activity
EAG14_03865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_03875	COG1538	Outer membrane efflux protein
EAG14_03880	COG2721	sulfolactate sulfo-lyase activity
EAG14_03885	COG1609	Transcriptional regulator
EAG14_03895	COG4948	Mandelate Racemase Muconate Lactonizing
EAG14_03905	COG0583	DNA-binding transcription factor activity
EAG14_03910	COG4948	Mandelate Racemase Muconate Lactonizing
EAG14_03980	COG2175	clavaminate synthase activity
EAG14_03990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_03995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_04010	COG3119	arylsulfatase activity
EAG14_04015	COG0583	DNA-binding transcription factor activity
EAG14_04020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_04070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_04105	COG2814	Major facilitator Superfamily
EAG14_04125	COG1960	acyl-CoA dehydrogenase activity
EAG14_04130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAG14_04135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_04145	COG1304	FMN binding
EAG14_04155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_04160	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EAG14_04165	COG4521	taurine ABC transporter
EAG14_04170	COG2175	clavaminate synthase activity
EAG14_04180	COG1045	serine acetyltransferase
EAG14_04190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAG14_04195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EAG14_04200	COG0798	PFAM Bile acid sodium symporter
EAG14_04225	COG5001	Diguanylate cyclase
EAG14_04225	COG3300	MHYT domain
EAG14_04240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAG14_04245	COG3045	CreA protein
EAG14_04260	COG1132	(ABC) transporter
EAG14_04295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_04310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EAG14_04315	COG4589	Belongs to the CDS family
EAG14_04355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAG14_04360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EAG14_04370	COG0557	exoribonuclease II activity
EAG14_04380	COG3150	esterase
EAG14_04385	COG2815	serine threonine protein kinase
EAG14_04385	COG0515	serine threonine protein kinase
EAG14_04390	COG0772	Belongs to the SEDS family
EAG14_04410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAG14_04420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAG14_04425	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_04430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAG14_04440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAG14_04445	COG2188	Transcriptional regulator
EAG14_04450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAG14_04460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_04485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAG14_04490	COG0745	RESPONSE REGULATOR receiver
EAG14_04495	COG0642	Histidine kinase
EAG14_04500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAG14_04505	COG1943	Transposase
EAG14_04510	COG1522	sequence-specific DNA binding
EAG14_04530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAG14_04535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAG14_04580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAG14_04590	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_04595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAG14_04620	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EAG14_04670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAG14_04690	COG1414	Transcriptional regulator
EAG14_04700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAG14_04705	COG0183	Belongs to the thiolase family
EAG14_04710	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_04715	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_04730	COG0511	ligase activity, forming carbon-carbon bonds
EAG14_04735	COG0439	Biotin carboxylase
EAG14_04740	COG2264	protein methyltransferase activity
EAG14_04770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EAG14_04770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAG14_04775	COG3023	N-Acetylmuramoyl-L-alanine amidase
EAG14_04795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAG14_04800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EAG14_04825	COG0314	molybdopterin synthase activity
EAG14_04830	COG0542	response to heat
EAG14_04845	COG2205	protein histidine kinase activity
EAG14_04845	COG0784	Response regulator, receiver
EAG14_04850	COG2197	response regulator
EAG14_04880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAG14_04885	COG0004	ammonium transporteR
EAG14_04895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAG14_04895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAG14_04930	COG4969	Belongs to the N-Me-Phe pilin family
EAG14_04940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EAG14_04945	COG1185	polyribonucleotide nucleotidyltransferase activity
EAG14_04950	COG0604	alcohol dehydrogenase
EAG14_04950	COG3321	synthase
EAG14_04950	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_04955	COG0149	triose-phosphate isomerase activity
EAG14_04970	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAG14_04975	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAG14_04980	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAG14_04985	COG0649	NAD binding
EAG14_04990	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EAG14_04995	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EAG14_05000	COG1034	ATP synthesis coupled electron transport
EAG14_05005	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EAG14_05010	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAG14_05020	COG0713	ATP synthesis coupled electron transport
EAG14_05035	COG1007	ATP synthesis coupled electron transport
EAG14_05050	COG0840	transmembrane signaling receptor activity
EAG14_05080	COG0071	Belongs to the small heat shock protein (HSP20) family
EAG14_05090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EAG14_05095	COG2814	Major facilitator Superfamily
EAG14_05110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAG14_05115	COG0584	glycerophosphoryl diester phosphodiesterase
EAG14_05120	COG0583	DNA-binding transcription factor activity
EAG14_05125	COG1473	amidohydrolase
EAG14_05135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EAG14_05140	COG0586	Pfam SNARE associated Golgi protein
EAG14_05150	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAG14_05155	COG0802	atpase or kinase
EAG14_05160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EAG14_05170	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_05175	COG4974	Belongs to the 'phage' integrase family
EAG14_05180	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_05190	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EAG14_05195	COG2833	Protein of unknown function (DUF455)
EAG14_05205	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EAG14_05220	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EAG14_05225	COG0148	phosphopyruvate hydratase activity
EAG14_05235	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EAG14_05240	COG0504	CTP synthase activity
EAG14_05245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EAG14_05250	COG0756	dUTP diphosphatase activity
EAG14_05260	COG1047	Peptidyl-prolyl cis-trans
EAG14_05265	COG2850	peptidyl-arginine hydroxylation
EAG14_05280	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EAG14_05285	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EAG14_05290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAG14_05305	COG0187	DNA topoisomerase II activity
EAG14_05310	COG0741	lytic transglycosylase activity
EAG14_05330	COG2308	Evidence 4 Homologs of previously reported genes of
EAG14_05340	COG4628	conserved protein (DUF2132)
EAG14_05365	COG1538	Outer membrane efflux protein
EAG14_05395	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EAG14_05405	COG4774	siderophore transport
EAG14_05410	COG4774	siderophore transport
EAG14_05440	COG0501	Belongs to the peptidase M48B family
EAG14_05480	COG3634	alkyl hydroperoxide reductase activity
EAG14_05485	COG4771	TonB-dependent receptor
EAG14_05495	COG3720	iron ion transport
EAG14_05500	COG4558	Periplasmic binding protein
EAG14_05505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAG14_05510	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EAG14_05520	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EAG14_05535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAG14_05555	COG0583	DNA-binding transcription factor activity
EAG14_05560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAG14_05565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAG14_05575	COG0840	transmembrane signaling receptor activity
EAG14_05605	COG1477	protein flavinylation
EAG14_05610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EAG14_05620	COG0358	DNA primase activity
EAG14_05625	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_05635	COG3540	Alkaline phosphatase
EAG14_05640	COG3706	GGDEF domain
EAG14_05650	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EAG14_05670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EAG14_05680	COG0105	UTP biosynthetic process
EAG14_05685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EAG14_05700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EAG14_05705	COG0124	histidyl-tRNA synthetase
EAG14_05715	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAG14_05720	COG1160	GTP binding
EAG14_05725	COG1923	regulation of RNA biosynthetic process
EAG14_05730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EAG14_05735	COG0330	HflC and HflK could
EAG14_05740	COG0330	HflC and HflK could
EAG14_05745	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EAG14_05750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EAG14_05785	COG1187	pseudouridine synthase activity
EAG14_05825	COG3852	Histidine kinase
EAG14_05830	COG2204	response regulator
EAG14_05835	COG0708	Exodeoxyribonuclease III
EAG14_05845	COG0277	FAD linked oxidase domain protein
EAG14_05860	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EAG14_05875	COG1595	DNA-templated transcription, initiation
EAG14_05880	COG3712	iron ion homeostasis
EAG14_05890	COG1175	transmembrane transport
EAG14_05895	COG0395	ABC-type sugar transport system, permease component
EAG14_05900	COG3842	ATPase activity
EAG14_05905	COG0246	Mannitol dehydrogenase
EAG14_05910	COG2207	Transcriptional regulator
EAG14_05915	COG1070	Carbohydrate kinase
EAG14_05960	COG0277	FAD linked oxidase domain protein
EAG14_05970	COG1295	ribonuclease BN
EAG14_05985	COG2267	carboxylic ester hydrolase activity
EAG14_06005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EAG14_06010	COG2814	Major facilitator Superfamily
EAG14_06020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EAG14_06025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EAG14_06030	COG0741	lytic transglycosylase activity
EAG14_06040	COG0456	acetyltransferase
EAG14_06055	COG0557	exoribonuclease II activity
EAG14_06060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EAG14_06060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EAG14_06065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAG14_06075	COG0052	Belongs to the universal ribosomal protein uS2 family
EAG14_06080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EAG14_06090	COG0233	cytoplasmic translational termination
EAG14_06100	COG0575	Belongs to the CDS family
EAG14_06105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EAG14_06110	COG0750	zinc metalloprotease
EAG14_06125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAG14_06130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EAG14_06135	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAG14_06140	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAG14_06145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EAG14_06150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAG14_06155	COG0505	Belongs to the CarA family
EAG14_06165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EAG14_06170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAG14_06185	COG1534	Rna-binding protein
EAG14_06190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EAG14_06195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAG14_06205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAG14_06250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EAG14_06255	COG0573	inorganic phosphate transmembrane transporter activity
EAG14_06260	COG0581	inorganic phosphate transmembrane transporter activity
EAG14_06265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EAG14_06270	COG0704	Plays a role in the regulation of phosphate uptake
EAG14_06275	COG0745	RESPONSE REGULATOR receiver
EAG14_06285	COG0534	Mate efflux family protein
EAG14_06295	COG0254	rRNA binding
EAG14_06300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EAG14_06335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EAG14_06340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EAG14_06345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EAG14_06365	COG0741	lytic transglycosylase activity
EAG14_06365	COG1388	LysM domain
EAG14_06370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_06380	COG0328	RNA-DNA hybrid ribonuclease activity
EAG14_06390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAG14_06395	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_06435	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
EAG14_06440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EAG14_06455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EAG14_06470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAG14_06475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAG14_06490	COG0322	excinuclease ABC activity
EAG14_06500	COG0776	regulation of translation
EAG14_06510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAG14_06530	COG0513	Belongs to the DEAD box helicase family
EAG14_06535	COG0488	(ABC) transporter
EAG14_06550	COG3191	aminopeptidase activity
EAG14_06570	COG2132	Multicopper oxidase
EAG14_06595	COG0789	Transcriptional regulator
EAG14_06625	COG0582	viral genome integration into host DNA
EAG14_06690	COG2816	NAD+ diphosphatase activity
EAG14_06695	COG0425	Belongs to the sulfur carrier protein TusA family
EAG14_06700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EAG14_06725	COG1982	Orn Lys Arg decarboxylase major
EAG14_06730	COG1793	dna ligase
EAG14_06740	COG4166	transmembrane transport
EAG14_06745	COG4174	ABC transporter (Permease)
EAG14_06760	COG4239	(ABC) transporter, permease
EAG14_06775	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EAG14_06790	COG0583	DNA-binding transcription factor activity
EAG14_06795	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_06800	COG0596	Alpha beta hydrolase
EAG14_06810	COG0066	3-isopropylmalate dehydratase activity
EAG14_06860	COG1609	Transcriptional regulator
EAG14_06875	COG0583	DNA-binding transcription factor activity
EAG14_06895	COG1063	alcohol dehydrogenase
EAG14_06900	COG3634	alkyl hydroperoxide reductase activity
EAG14_06905	COG1959	2 iron, 2 sulfur cluster binding
EAG14_06925	COG0477	Major facilitator Superfamily
EAG14_06930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EAG14_06940	COG2863	cytochrome
EAG14_06955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EAG14_06960	COG0779	Required for maturation of 30S ribosomal subunits
EAG14_06965	COG0195	Participates in both transcription termination and antitermination
EAG14_06970	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EAG14_06975	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EAG14_06980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EAG14_06995	COG1024	Enoyl-CoA hydratase
EAG14_07000	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EAG14_07005	COG2867	negative regulation of translational initiation
EAG14_07010	COG2914	Belongs to the UPF0125 (RnfH) family
EAG14_07035	COG0519	Catalyzes the synthesis of GMP from XMP
EAG14_07035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EAG14_07080	COG0506	proline dehydrogenase activity
EAG14_07080	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAG14_07080	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAG14_07095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAG14_07105	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EAG14_07145	COG3128	pkhd-type hydroxylase
EAG14_07150	COG4774	siderophore transport
EAG14_07175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EAG14_07180	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EAG14_07185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EAG14_07190	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EAG14_07195	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EAG14_07200	COG0072	phenylalanine-tRNA ligase activity
EAG14_07200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAG14_07205	COG0776	regulation of translation
EAG14_07210	COG0789	Transcriptional regulator
EAG14_07240	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EAG14_07245	COG0308	aminopeptidase N
EAG14_07250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAG14_07260	COG2267	carboxylic ester hydrolase activity
EAG14_07265	COG2207	Transcriptional regulator
EAG14_07270	COG4638	Rieske (2fe-2S)
EAG14_07275	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EAG14_07280	COG2146	nitrite reductase [NAD(P)H] activity
EAG14_07290	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAG14_07305	COG0410	ABC transporter
EAG14_07315	COG0667	Aldo Keto reductase
EAG14_07320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EAG14_07325	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_07330	COG0583	DNA-binding transcription factor activity
EAG14_07335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAG14_07340	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EAG14_07355	COG1666	GTP binding
EAG14_07360	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EAG14_07375	COG0137	argininosuccinate synthase activity
EAG14_07380	COG3123	guanosine phosphorylase activity
EAG14_07390	COG1393	Belongs to the ArsC family
EAG14_07395	COG0285	dihydrofolate synthase activity
EAG14_07415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAG14_07460	COG1840	ABC-type Fe3 transport system, periplasmic component
EAG14_07465	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EAG14_07470	COG0642	Histidine kinase
EAG14_07500	COG2204	response regulator
EAG14_07510	COG0411	ABC transporter
EAG14_07515	COG0410	ABC transporter
EAG14_07555	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EAG14_07565	COG1335	isochorismatase
EAG14_07570	COG1741	Belongs to the pirin family
EAG14_07575	COG0583	DNA-binding transcription factor activity
EAG14_07580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAG14_07595	COG0415	Belongs to the DNA photolyase family
EAG14_07600	COG3046	protein related to deoxyribodipyrimidine photolyase
EAG14_07615	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAG14_07620	COG0024	Methionine aminopeptidase
EAG14_07630	COG3339	Conserved Protein
EAG14_07645	COG1067	ATP-dependent peptidase activity
EAG14_07650	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EAG14_07655	COG1011	Hydrolase
EAG14_07670	COG1253	flavin adenine dinucleotide binding
EAG14_07680	COG0642	Histidine kinase
EAG14_07695	COG3706	GGDEF domain
EAG14_07705	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EAG14_07710	COG1562	ergosterol biosynthetic process
EAG14_07720	COG1760	l-serine dehydratase
EAG14_07725	COG1562	ergosterol biosynthetic process
EAG14_07745	COG0544	peptidyl-prolyl cis-trans isomerase activity
EAG14_07750	COG0740	serine-type endopeptidase activity
EAG14_07755	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EAG14_07760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EAG14_07790	COG1451	nucleotide metabolic process
EAG14_07795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EAG14_07805	COG0114	fumarate hydratase activity
EAG14_07825	COG4654	Cytochrome c, class I
EAG14_07835	COG0129	dihydroxy-acid dehydratase activity
EAG14_07845	COG4774	siderophore transport
EAG14_07850	COG3712	iron ion homeostasis
EAG14_07860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EAG14_07875	COG1802	Transcriptional regulator
EAG14_07895	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_07905	COG0583	DNA-binding transcription factor activity
EAG14_07920	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAG14_07930	COG1137	ATPase activity
EAG14_07955	COG3278	Belongs to the heme-copper respiratory oxidase family
EAG14_07990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAG14_08005	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EAG14_08015	COG0730	response to heat
EAG14_08030	COG4206	TonB-dependent receptor
EAG14_08045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EAG14_08050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAG14_08055	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EAG14_08060	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EAG14_08065	COG0778	Nitroreductase
EAG14_08070	COG1611	Belongs to the LOG family
EAG14_08075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EAG14_08110	COG1320	monovalent cation:proton antiporter activity
EAG14_08115	COG2212	antiporter activity
EAG14_08120	COG1863	multisubunit Na H antiporter MnhE subunit
EAG14_08125	COG0651	ATP synthesis coupled electron transport
EAG14_08130	COG1006	Multisubunit Na H antiporter MnhC subunit
EAG14_08135	COG2111	Na H antiporter
EAG14_08135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAG14_08145	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EAG14_08155	COG0776	regulation of translation
EAG14_08165	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EAG14_08170	COG0287	Prephenate dehydrogenase
EAG14_08175	COG0077	Prephenate dehydratase
EAG14_08175	COG1605	Chorismate mutase
EAG14_08180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EAG14_08195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EAG14_08200	COG0546	phosphoglycolate phosphatase activity
EAG14_08265	COG2197	response regulator
EAG14_08270	COG4585	Histidine kinase
EAG14_08280	COG0123	including yeast histone deacetylase and acetoin utilization protein
EAG14_08290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EAG14_08310	COG1322	Protein conserved in bacteria
EAG14_08325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EAG14_08340	COG1492	cobalamin metabolic process
EAG14_08345	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EAG14_08365	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAG14_08375	COG1802	Transcriptional regulator
EAG14_08390	COG3654	unkown
EAG14_08395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EAG14_08400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_08420	COG0513	Belongs to the DEAD box helicase family
EAG14_08430	COG0023	Translation Initiation Factor
EAG14_08445	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EAG14_08450	COG1959	2 iron, 2 sulfur cluster binding
EAG14_08460	COG0560	Phosphoserine phosphatase
EAG14_08470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAG14_08490	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EAG14_08495	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EAG14_08495	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EAG14_08500	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EAG14_08510	COG2205	protein histidine kinase activity
EAG14_08515	COG0745	RESPONSE REGULATOR receiver
EAG14_08540	COG0746	molybdenum cofactor guanylyltransferase activity
EAG14_08545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EAG14_08570	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_08575	COG3039	Transposase
EAG14_08600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EAG14_08615	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EAG14_08615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAG14_08620	COG0347	Belongs to the P(II) protein family
EAG14_08630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EAG14_08650	COG1595	DNA-templated transcription, initiation
EAG14_08655	COG0028	Belongs to the TPP enzyme family
EAG14_08660	COG0440	acetolactate synthase activity
EAG14_08665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EAG14_08670	COG1183	phosphatidylcholine synthase activity
EAG14_08675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAG14_08685	COG1414	Transcriptional regulator
EAG14_08690	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EAG14_08695	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EAG14_08710	COG2832	Protein of unknown function (DUF454)
EAG14_08715	COG2873	o-acetylhomoserine
EAG14_08720	COG0826	peptidase U32
EAG14_08755	COG0590	tRNA wobble adenosine to inosine editing
EAG14_08760	COG1619	proteins homologs of microcin C7 resistance protein MccF
EAG14_08770	COG0242	peptide deformylase activity
EAG14_08785	COG0024	Methionine aminopeptidase
EAG14_08790	COG0047	phosphoribosylformylglycinamidine synthase activity
EAG14_08790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAG14_08805	COG3047	cAMP biosynthetic process
EAG14_08900	COG1538	Outer membrane efflux protein
EAG14_08910	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EAG14_08925	COG1309	transcriptional regulator
EAG14_08930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EAG14_08940	COG1136	(ABC) transporter
EAG14_08940	COG0577	efflux transmembrane transporter activity
EAG14_08990	COG1024	Enoyl-CoA hydratase
EAG14_08995	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_09010	COG2022	thiamine diphosphate biosynthetic process
EAG14_09025	COG0351	phosphomethylpyrimidine kinase
EAG14_09035	COG0564	pseudouridine synthase activity
EAG14_09040	COG0840	transmembrane signaling receptor activity
EAG14_09050	COG2183	response to ionizing radiation
EAG14_09100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EAG14_09105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EAG14_09110	COG0470	DNA polymerase III
EAG14_09120	COG0084	hydrolase, TatD family'
EAG14_09130	COG1132	(ABC) transporter
EAG14_09135	COG0823	Involved in the tonB-independent uptake of proteins
EAG14_09140	COG2885	chlorophyll binding
EAG14_09150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EAG14_09160	COG0217	transcriptional regulatory protein
EAG14_09165	COG0484	heat shock protein binding
EAG14_09190	COG3706	GGDEF domain
EAG14_09200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_09205	COG0842	Transport permease protein
EAG14_09205	COG1129	ABC transporter
EAG14_09210	COG0842	Transport permease protein
EAG14_09215	COG0402	S-adenosylhomocysteine deaminase activity
EAG14_09230	COG4603	Belongs to the binding-protein-dependent transport system permease family
EAG14_09245	COG1744	ABC transporter substrate-binding protein PnrA-like
EAG14_09255	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EAG14_09270	COG0765	amino acid transport
EAG14_09285	COG0433	COG0433 Predicted ATPase
EAG14_09290	COG0217	transcriptional regulatory protein
EAG14_09295	COG0151	Belongs to the GarS family
EAG14_09300	COG0408	coproporphyrinogen oxidase activity
EAG14_09305	COG0799	negative regulation of ribosome biogenesis
EAG14_09310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EAG14_09315	COG0424	maF-like protein
EAG14_09320	COG1530	ribonuclease E activity
EAG14_09325	COG0625	glutathione transferase activity
EAG14_09335	COG0745	RESPONSE REGULATOR receiver
EAG14_09340	COG2205	protein histidine kinase activity
EAG14_09345	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EAG14_09350	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EAG14_09355	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EAG14_09385	COG0436	Aminotransferase
EAG14_09390	COG0583	DNA-binding transcription factor activity
EAG14_09410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EAG14_09430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAG14_09435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EAG14_09440	COG0252	asparaginase activity
EAG14_09445	COG0563	adenylate kinase activity
EAG14_09450	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EAG14_09455	COG2835	tetraacyldisaccharide 4'-kinase activity
EAG14_09460	COG2835	tetraacyldisaccharide 4'-kinase activity
EAG14_09460	COG1663	tetraacyldisaccharide 4'-kinase activity
EAG14_09465	COG0848	biopolymer transport protein
EAG14_09470	COG0811	peptide transport
EAG14_09475	COG1570	exodeoxyribonuclease VII activity
EAG14_09495	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EAG14_09500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_09510	COG0747	negative chemotaxis
EAG14_09555	COG1960	acyl-CoA dehydrogenase activity
EAG14_09600	COG2814	Major facilitator Superfamily
EAG14_09605	COG1566	PFAM secretion protein HlyD family protein
EAG14_09610	COG1538	Outer membrane efflux protein
EAG14_09620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EAG14_09625	COG0583	DNA-binding transcription factor activity
EAG14_09645	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_09650	COG2706	6-phosphogluconolactonase activity
EAG14_09680	COG0492	ferredoxin-NADP+ reductase activity
EAG14_09685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EAG14_09690	COG2895	sulfate adenylyltransferase (ATP) activity
EAG14_09690	COG0529	Catalyzes the synthesis of activated sulfate
EAG14_09695	COG0175	sulfate reduction
EAG14_09700	COG0175	sulfate reduction
EAG14_09715	COG0730	response to heat
EAG14_09725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EAG14_09730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EAG14_09735	COG0431	NADPH-dependent FMN reductase
EAG14_09740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_09745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_09755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_09760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_09765	COG1116	anion transmembrane transporter activity
EAG14_09775	COG1309	transcriptional regulator
EAG14_09780	COG0604	alcohol dehydrogenase
EAG14_09800	COG0259	pyridoxamine-phosphate oxidase activity
EAG14_09805	COG1309	transcriptional regulator
EAG14_09855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAG14_09860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EAG14_09870	COG2032	superoxide dismutase activity
EAG14_09880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAG14_09885	COG0587	DNA-directed DNA polymerase activity
EAG14_09895	COG1196	nuclear chromosome segregation
EAG14_09905	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EAG14_09910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAG14_09955	COG0183	Belongs to the thiolase family
EAG14_09960	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_09970	COG2890	protein-(glutamine-N5) methyltransferase activity
EAG14_09975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EAG14_09985	COG2171	N-acyltransferase activity
EAG14_09990	COG0436	Aminotransferase
EAG14_09995	COG0840	transmembrane signaling receptor activity
EAG14_10000	COG2878	Part of a membrane complex involved in electron transport
EAG14_10020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAG14_10030	COG1522	sequence-specific DNA binding
EAG14_10040	COG1022	Amp-dependent synthetase and ligase
EAG14_10045	COG1802	Transcriptional regulator
EAG14_10060	COG1703	isobutyryl-CoA mutase activity
EAG14_10065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EAG14_10075	COG0439	Biotin carboxylase
EAG14_10100	COG3437	response regulator, receiver
EAG14_10130	COG0640	Transcriptional regulator
EAG14_10145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_10145	COG3453	Protein conserved in bacteria
EAG14_10205	COG1191	sigma factor activity
EAG14_10235	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EAG14_10250	COG1157	protein secretion by the type III secretion system
EAG14_10275	COG1677	Flagellar hook-basal body complex protein FliE
EAG14_10280	COG1558	bacterial-type flagellum-dependent cell motility
EAG14_10290	COG1706	bacterial-type flagellum-dependent cell motility
EAG14_10295	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EAG14_10305	COG4786	Flagellar basal body rod
EAG14_10310	COG4786	Flagellar basal body rod
EAG14_10315	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAG14_10320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAG14_10325	COG1684	flagellar biosynthetic protein fliR
EAG14_10330	COG1987	bacterial-type flagellum assembly
EAG14_10335	COG3591	Belongs to the peptidase S1B family
EAG14_10335	COG1864	DNA RNA non-specific endonuclease
EAG14_10430	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_10435	COG0534	Mate efflux family protein
EAG14_10460	COG0346	lactoylglutathione lyase activity
EAG14_10470	COG0791	NLP P60 protein
EAG14_10515	COG0745	RESPONSE REGULATOR receiver
EAG14_10530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EAG14_10540	COG0517	IMP dehydrogenase activity
EAG14_10540	COG0516	GMP reductase activity
EAG14_10565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EAG14_10570	COG0494	nUDIX hydrolase
EAG14_10580	COG1349	DNA-binding transcription factor activity
EAG14_10585	COG0583	DNA-binding transcription factor activity
EAG14_10590	COG0697	spore germination
EAG14_10600	COG5000	phosphorelay sensor kinase activity
EAG14_10610	COG1090	epimerase
EAG14_10630	COG0527	aspartate kinase activity
EAG14_10650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAG14_10655	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAG14_10660	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EAG14_10670	COG4566	intracellular signal transduction
EAG14_10675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EAG14_10690	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EAG14_10695	COG0167	dihydroorotate dehydrogenase activity
EAG14_10715	COG0579	oxidoreductase
EAG14_10745	COG0443	Heat shock 70 kDa protein
EAG14_10765	COG1104	cysteine desulfurase activity
EAG14_10770	COG1959	2 iron, 2 sulfur cluster binding
EAG14_10790	COG3384	dioxygenase
EAG14_10795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAG14_10850	COG4608	Belongs to the ABC transporter superfamily
EAG14_10855	COG0444	Belongs to the ABC transporter superfamily
EAG14_10860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_10865	COG0601	transmembrane transport
EAG14_10870	COG2072	flavoprotein involved in K transport
EAG14_10880	COG1739	Uncharacterized protein family UPF0029
EAG14_10895	COG0154	amidase activity
EAG14_10900	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_10905	COG3048	D-serine ammonia-lyase activity
EAG14_10945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAG14_10950	COG4181	ATPase activity
EAG14_10970	COG0626	cystathionine gamma-synthase activity
EAG14_10985	COG0745	RESPONSE REGULATOR receiver
EAG14_10985	COG3706	GGDEF domain
EAG14_10990	COG0455	bacterial-type flagellum organization
EAG14_11000	COG1741	Belongs to the pirin family
EAG14_11010	COG1741	Belongs to the pirin family
EAG14_11015	COG0583	DNA-binding transcription factor activity
EAG14_11025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAG14_11030	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EAG14_11035	COG3706	GGDEF domain
EAG14_11055	COG1538	Outer membrane efflux protein
EAG14_11060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAG14_11065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_11090	COG3706	GGDEF domain
EAG14_11095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EAG14_11100	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EAG14_11105	COG4208	sulfate ABC transporter
EAG14_11115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EAG14_11125	COG0450	alkyl hydroperoxide reductase
EAG14_11130	COG0840	transmembrane signaling receptor activity
EAG14_11135	COG0700	Nucleoside recognition
EAG14_11165	COG2925	Exonuclease
EAG14_11170	COG2951	lytic endotransglycosylase activity
EAG14_11185	COG1301	dicarboxylic acid transport
EAG14_11190	COG0542	response to heat
EAG14_11195	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EAG14_11210	COG1199	ATP-dependent helicase activity
EAG14_11225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EAG14_11230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAG14_11235	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAG14_11240	COG0567	Dehydrogenase, E1 component
EAG14_11260	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_11265	COG1643	Atp-dependent helicase
EAG14_11280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EAG14_11280	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EAG14_11290	COG0583	DNA-binding transcription factor activity
EAG14_11295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EAG14_11305	COG3300	MHYT domain
EAG14_11305	COG5001	Diguanylate cyclase
EAG14_11325	COG4651	solute:proton antiporter activity
EAG14_11325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAG14_11335	COG2011	ABC-type metal ion transport system permease component
EAG14_11340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAG14_11345	COG2814	Major facilitator Superfamily
EAG14_11350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAG14_11365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAG14_11395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_11410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EAG14_11415	COG0509	glycine decarboxylation via glycine cleavage system
EAG14_11420	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EAG14_11420	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EAG14_11425	COG0494	nUDIX hydrolase
EAG14_11430	COG0545	Peptidyl-prolyl cis-trans isomerase
EAG14_11435	COG0789	Transcriptional regulator
EAG14_11455	COG0564	pseudouridine synthase activity
EAG14_11465	COG2197	response regulator
EAG14_11470	COG3916	Acyl-homoserine-lactone synthase
EAG14_11475	COG0529	Catalyzes the synthesis of activated sulfate
EAG14_11490	COG0840	transmembrane signaling receptor activity
EAG14_11495	COG0697	spore germination
EAG14_11500	COG1846	Transcriptional regulator
EAG14_11505	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_11510	COG0183	Belongs to the thiolase family
EAG14_11520	COG0589	response to stress
EAG14_11530	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EAG14_11545	COG0745	RESPONSE REGULATOR receiver
EAG14_11550	COG2851	Citrate transporter
EAG14_11555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_11565	COG3842	ATPase activity
EAG14_11575	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAG14_11580	COG1177	transmembrane transport
EAG14_11585	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_11660	COG2153	protein acetylation
EAG14_11665	COG2130	NADP-dependent
EAG14_11680	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_11685	COG1960	acyl-CoA dehydrogenase activity
EAG14_11690	COG0183	Belongs to the thiolase family
EAG14_11695	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_11695	COG1024	Enoyl-CoA hydratase
EAG14_11700	COG4716	Myosin-crossreactive antigen
EAG14_11710	COG0411	ABC transporter
EAG14_11730	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_11735	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EAG14_11740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EAG14_11745	COG2917	probably involved in intracellular septation
EAG14_11755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAG14_11770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EAG14_11780	COG0688	phosphatidylethanolamine metabolic process
EAG14_11800	COG1228	amidohydrolase
EAG14_11810	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EAG14_11815	COG2986	histidine ammonia-lyase
EAG14_11830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_11840	COG2205	protein histidine kinase activity
EAG14_11845	COG0745	RESPONSE REGULATOR receiver
EAG14_11870	COG0037	tRNA processing
EAG14_11875	COG0825	malonyl-CoA metabolic process
EAG14_11885	COG0215	cysteine-tRNA ligase activity
EAG14_11910	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAG14_11915	COG3228	Belongs to the MtfA family
EAG14_11925	COG1522	sequence-specific DNA binding
EAG14_11950	COG3384	dioxygenase
EAG14_11965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAG14_12025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_12030	COG0590	tRNA wobble adenosine to inosine editing
EAG14_12050	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EAG14_12150	COG0564	pseudouridine synthase activity
EAG14_12185	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_12195	COG0633	Ferredoxin
EAG14_12205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EAG14_12210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EAG14_12215	COG0436	Aminotransferase
EAG14_12220	COG0824	Thioesterase
EAG14_12270	COG0039	L-malate dehydrogenase activity
EAG14_12275	COG2188	Transcriptional regulator
EAG14_12295	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAG14_12300	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EAG14_12305	COG0372	Belongs to the citrate synthase family
EAG14_12330	COG2194	sulfuric ester hydrolase activity
EAG14_12340	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_12345	COG0473	3-isopropylmalate dehydrogenase activity
EAG14_12355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_12360	COG0601	transmembrane transport
EAG14_12370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAG14_12380	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_12390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAG14_12400	COG1522	sequence-specific DNA binding
EAG14_12440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAG14_12445	COG0583	DNA-binding transcription factor activity
EAG14_12460	COG0667	Aldo Keto reductase
EAG14_12480	COG0840	transmembrane signaling receptor activity
EAG14_12510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_12515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAG14_12530	COG1271	oxidase subunit
EAG14_12535	COG1294	oxidase, subunit
EAG14_12545	COG1960	acyl-CoA dehydrogenase activity
EAG14_12575	COG0714	Associated with various cellular activities
EAG14_12590	COG2951	lytic endotransglycosylase activity
EAG14_12595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_12620	COG1473	amidohydrolase
EAG14_12625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_12630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_12635	COG0683	leucine binding
EAG14_12645	COG1136	(ABC) transporter
EAG14_12645	COG0577	efflux transmembrane transporter activity
EAG14_12650	COG1136	(ABC) transporter
EAG14_12650	COG0577	efflux transmembrane transporter activity
EAG14_12655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_12660	COG1538	Outer membrane efflux protein
EAG14_12670	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_12675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EAG14_12690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_12695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_12700	COG1116	anion transmembrane transporter activity
EAG14_12705	COG0840	transmembrane signaling receptor activity
EAG14_12710	COG0517	IMP dehydrogenase activity
EAG14_12715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_12720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAG14_12725	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EAG14_12730	COG3265	gluconokinase activity
EAG14_12735	COG1609	Transcriptional regulator
EAG14_12755	COG0840	transmembrane signaling receptor activity
EAG14_12760	COG2223	nitrite transmembrane transporter activity
EAG14_12765	COG2815	serine threonine protein kinase
EAG14_12765	COG0515	serine threonine protein kinase
EAG14_12770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAG14_12785	COG0243	molybdopterin cofactor binding
EAG14_12790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAG14_12800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EAG14_12800	COG5297	Belongs to the glycosyl hydrolase family 6
EAG14_12805	COG1607	acyl-coa hydrolase
EAG14_12830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EAG14_12845	COG0583	DNA-binding transcription factor activity
EAG14_12885	COG2721	sulfolactate sulfo-lyase activity
EAG14_12915	COG0312	modulator of DNA gyrase
EAG14_12920	COG3028	Belongs to the UPF0307 family
EAG14_12925	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAG14_12935	COG1045	serine acetyltransferase
EAG14_12960	COG5001	Diguanylate cyclase
EAG14_12965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EAG14_12990	COG5001	Diguanylate cyclase
EAG14_13000	COG1968	undecaprenyl-diphosphatase activity
EAG14_13015	COG2972	Histidine kinase
EAG14_13030	COG5001	Diguanylate cyclase
EAG14_13030	COG3447	MASE1 domain protein
EAG14_13030	COG5002	protein histidine kinase activity
EAG14_13060	COG1280	lysine exporter protein (LysE YggA)
EAG14_13065	COG4133	protoheme IX ABC transporter activity
EAG14_13085	COG2205	protein histidine kinase activity
EAG14_13085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_13095	COG0745	RESPONSE REGULATOR receiver
EAG14_13100	COG0745	RESPONSE REGULATOR receiver
EAG14_13100	COG3706	GGDEF domain
EAG14_13115	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EAG14_13115	COG3608	succinylglutamate desuccinylase aspartoacylase
EAG14_13150	COG3284	Transcriptional regulator
EAG14_13165	COG0789	Transcriptional regulator
EAG14_13175	COG0655	NAD(P)H dehydrogenase (quinone) activity
EAG14_13195	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EAG14_13230	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EAG14_13240	COG1910	domain protein
EAG14_13250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAG14_13255	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EAG14_13260	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EAG14_13270	COG1722	exodeoxyribonuclease VII activity
EAG14_13310	COG5001	Diguanylate cyclase
EAG14_13310	COG3300	MHYT domain
EAG14_13320	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EAG14_13325	COG0181	hydroxymethylbilane synthase activity
EAG14_13375	COG0583	DNA-binding transcription factor activity
EAG14_13380	COG1960	acyl-CoA dehydrogenase activity
EAG14_13400	COG2326	polyphosphate kinase activity
EAG14_13420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_13425	COG0129	dihydroxy-acid dehydratase activity
EAG14_13435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EAG14_13440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAG14_13445	COG0277	FAD linked oxidase domain protein
EAG14_13450	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_13455	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAG14_13460	COG0835	chemotaxis
EAG14_13460	COG0784	Response regulator, receiver
EAG14_13495	COG0617	tRNA 3'-terminal CCA addition
EAG14_13505	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EAG14_13510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EAG14_13555	COG2912	Transglutaminase-like superfamily
EAG14_13560	COG0728	peptidoglycan biosynthetic process
EAG14_13565	COG0268	Binds directly to 16S ribosomal RNA
EAG14_13575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAG14_13580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EAG14_13640	COG0642	Histidine kinase
EAG14_13650	COG0840	transmembrane signaling receptor activity
EAG14_13660	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EAG14_13670	COG3483	tryptophan 2,3-dioxygenase activity
EAG14_13715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EAG14_13720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAG14_13725	COG5001	Diguanylate cyclase
EAG14_13735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EAG14_13740	COG2916	Histone family protein nucleoid-structuring protein H-NS
EAG14_13745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EAG14_13755	COG3245	cytochrome
EAG14_13765	COG4263	nitrous-oxide reductase activity
EAG14_13770	COG0348	domain, Protein
EAG14_13770	COG3901	Regulator of nitric oxide reductase transcription
EAG14_13800	COG0513	Belongs to the DEAD box helicase family
EAG14_13805	COG2321	neutral zinc metallopeptidase
EAG14_13810	COG3706	GGDEF domain
EAG14_13810	COG0745	RESPONSE REGULATOR receiver
EAG14_13815	COG0717	Belongs to the dCTP deaminase family
EAG14_13820	COG0402	S-adenosylhomocysteine deaminase activity
EAG14_13830	COG0840	transmembrane signaling receptor activity
EAG14_13855	COG1129	ABC transporter
EAG14_13870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EAG14_13875	COG3706	GGDEF domain
EAG14_13895	COG5001	Diguanylate cyclase
EAG14_13895	COG3300	MHYT domain
EAG14_13930	COG0405	Gamma-glutamyltransferase
EAG14_13965	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_13975	COG0583	DNA-binding transcription factor activity
EAG14_14000	COG1301	dicarboxylic acid transport
EAG14_14005	COG0840	transmembrane signaling receptor activity
EAG14_14010	COG0281	malic enzyme
EAG14_14010	COG0280	phosphate acetyltransferase
EAG14_14015	COG1639	'signal transduction protein
EAG14_14025	COG1116	anion transmembrane transporter activity
EAG14_14030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_14040	COG1752	Esterase of the alpha-beta hydrolase superfamily
EAG14_14045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAG14_14050	COG2721	sulfolactate sulfo-lyase activity
EAG14_14055	COG0246	Mannitol dehydrogenase
EAG14_14060	COG1063	alcohol dehydrogenase
EAG14_14065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_14075	COG0765	amino acid transport
EAG14_14090	COG2186	Transcriptional regulator
EAG14_14095	COG2610	gluconate transmembrane transporter activity
EAG14_14100	COG2084	Dehydrogenase
EAG14_14105	COG3395	kinase activity
EAG14_14110	COG0235	Class ii aldolase
EAG14_14120	COG3622	Belongs to the hyi family
EAG14_14125	COG0829	nickel cation binding
EAG14_14130	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAG14_14140	COG0436	Aminotransferase
EAG14_14145	COG2814	Major facilitator Superfamily
EAG14_14175	COG0410	ABC transporter
EAG14_14195	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAG14_14215	COG3706	GGDEF domain
EAG14_14215	COG0745	RESPONSE REGULATOR receiver
EAG14_14220	COG4770	biotin carboxylase activity
EAG14_14225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EAG14_14230	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EAG14_14235	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EAG14_14265	COG3706	GGDEF domain
EAG14_14295	COG0831	urea catabolic process
EAG14_14305	COG0832	Belongs to the urease beta subunit family
EAG14_14310	COG0804	urea catabolic process
EAG14_14315	COG0454	-acetyltransferase
EAG14_14320	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EAG14_14325	COG0830	nickel cation binding
EAG14_14340	COG0582	viral genome integration into host DNA
EAG14_14440	COG4695	Portal protein
EAG14_14475	COG1902	pentaerythritol trinitrate reductase activity
EAG14_14490	COG2346	COG2346, Truncated hemoglobins
EAG14_14495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_14500	COG0765	amino acid transport
EAG14_14505	COG0765	amino acid transport
EAG14_14515	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EAG14_14525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EAG14_14545	COG0437	4 iron, 4 sulfur cluster binding
EAG14_14550	COG0243	molybdopterin cofactor binding
EAG14_14550	COG3383	formate dehydrogenase (NAD+) activity
EAG14_14580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EAG14_14590	COG0243	molybdopterin cofactor binding
EAG14_14600	COG0583	DNA-binding transcription factor activity
EAG14_14605	COG0489	protein tyrosine kinase activity
EAG14_14620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAG14_14620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAG14_14645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EAG14_14650	COG0602	queuosine metabolic process
EAG14_14655	COG0720	synthase
EAG14_14670	COG0156	8-amino-7-oxononanoate synthase activity
EAG14_14690	COG0583	DNA-binding transcription factor activity
EAG14_14710	COG2205	protein histidine kinase activity
EAG14_14720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EAG14_14735	COG2203	Gaf domain
EAG14_14735	COG3706	GGDEF domain
EAG14_14735	COG5001	Diguanylate cyclase
EAG14_14735	COG4251	negative regulation of phosphorylation
EAG14_14740	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EAG14_14745	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EAG14_14755	COG0210	DNA helicase
EAG14_14765	COG0516	GMP reductase activity
EAG14_14775	COG2084	Dehydrogenase
EAG14_14840	COG2814	Major facilitator Superfamily
EAG14_14845	COG3706	GGDEF domain
EAG14_14850	COG0513	Belongs to the DEAD box helicase family
EAG14_14855	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EAG14_14865	COG2154	pterin-4-alpha-carbinolamine dehydratase
EAG14_14870	COG1162	GTPase activity
EAG14_14875	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EAG14_14885	COG0335	large ribosomal subunit rRNA binding
EAG14_14890	COG0336	Belongs to the RNA methyltransferase TrmD family
EAG14_14895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EAG14_14900	COG0228	four-way junction DNA binding
EAG14_14915	COG0306	phosphate transporter
EAG14_14920	COG1392	Phosphate transport regulator
EAG14_14935	COG0411	ABC transporter
EAG14_14945	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAG14_14950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EAG14_14955	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EAG14_14960	COG1674	ftsk spoiiie
EAG14_14970	COG0492	ferredoxin-NADP+ reductase activity
EAG14_14975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EAG14_14980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EAG14_14985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_15000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EAG14_15000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EAG14_15015	COG2205	protein histidine kinase activity
EAG14_15030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EAG14_15035	COG3132	Protein of unknown function, DUF480
EAG14_15050	COG1960	acyl-CoA dehydrogenase activity
EAG14_15055	COG1960	acyl-CoA dehydrogenase activity
EAG14_15075	COG0745	RESPONSE REGULATOR receiver
EAG14_15080	COG5002	protein histidine kinase activity
EAG14_15085	COG2264	protein methyltransferase activity
EAG14_15090	COG3781	membrane
EAG14_15100	COG0196	riboflavin kinase activity
EAG14_15105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EAG14_15110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EAG14_15115	COG1283	sodium-dependent phosphate transmembrane transporter activity
EAG14_15120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EAG14_15130	COG0583	DNA-binding transcription factor activity
EAG14_15150	COG0697	spore germination
EAG14_15165	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_15195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAG14_15210	COG0084	hydrolase, TatD family'
EAG14_15220	COG1136	(ABC) transporter
EAG14_15225	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAG14_15235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EAG14_15240	COG0840	transmembrane signaling receptor activity
EAG14_15245	COG0613	PHP domain protein
EAG14_15250	COG0009	L-threonylcarbamoyladenylate synthase
EAG14_15255	COG0840	transmembrane signaling receptor activity
EAG14_15260	COG1994	Peptidase M50
EAG14_15265	COG0180	Tryptophanyl-tRNA synthetase
EAG14_15280	COG0745	RESPONSE REGULATOR receiver
EAG14_15295	COG1396	sequence-specific DNA binding
EAG14_15295	COG3800	Transcriptional regulator
EAG14_15315	COG2828	Protein conserved in bacteria
EAG14_15325	COG1116	anion transmembrane transporter activity
EAG14_15330	COG0395	ABC-type sugar transport system, permease component
EAG14_15335	COG1609	Transcriptional regulator
EAG14_15350	COG1177	transmembrane transport
EAG14_15355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EAG14_15395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EAG14_15400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAG14_15405	COG2239	Acts as a magnesium transporter
EAG14_15410	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EAG14_15415	COG1047	Peptidyl-prolyl cis-trans
EAG14_15420	COG2003	Belongs to the UPF0758 family
EAG14_15425	COG1193	negative regulation of DNA recombination
EAG14_15430	COG0737	Belongs to the 5'-nucleotidase family
EAG14_15440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAG14_15445	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EAG14_15450	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EAG14_15465	COG1561	YicC-like family, N-terminal region
EAG14_15470	COG0194	GDP metabolic process
EAG14_15475	COG1758	RNA polymerase activity
EAG14_15480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAG14_15500	COG1420	regulation of RNA biosynthetic process
EAG14_15505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EAG14_15510	COG0497	DNA recombination
EAG14_15515	COG1660	Displays ATPase and GTPase activities
EAG14_15520	COG1194	a g-specific adenine glycosylase
EAG14_15530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EAG14_15545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EAG14_15555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAG14_15560	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EAG14_15565	COG0193	aminoacyl-tRNA hydrolase activity
EAG14_15570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAG14_15580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_15590	COG4608	Belongs to the ABC transporter superfamily
EAG14_15595	COG0747	negative chemotaxis
EAG14_15600	COG0154	amidase activity
EAG14_15630	COG2258	MOSC domain
EAG14_15635	COG0588	phosphoglycerate mutase activity
EAG14_15640	COG1280	lysine exporter protein (LysE YggA)
EAG14_15665	COG0302	gtp cyclohydrolase
EAG14_15695	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EAG14_15715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EAG14_15730	COG2226	methyltransferase
EAG14_15755	COG3217	Mosc domain protein beta barrel domain protein
EAG14_15755	COG0633	Ferredoxin
EAG14_15760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAG14_15765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAG14_15775	COG1024	Enoyl-CoA hydratase
EAG14_15790	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_15795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EAG14_15810	COG0412	Dienelactone hydrolase
EAG14_15845	COG0625	glutathione transferase activity
EAG14_15865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAG14_15920	COG5487	UPF0391 membrane protein
EAG14_15925	COG4585	Histidine kinase
EAG14_15945	COG0793	Belongs to the peptidase S41A family
EAG14_15950	COG0588	phosphoglycerate mutase activity
EAG14_15955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAG14_15970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EAG14_15975	COG0019	diaminopimelate decarboxylase activity
EAG14_15980	COG0583	DNA-binding transcription factor activity
EAG14_15985	COG0724	RNA recognition motif
EAG14_15995	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EAG14_16005	COG0612	Peptidase, M16
EAG14_16010	COG0612	Peptidase, M16
EAG14_16030	COG5001	Diguanylate cyclase
EAG14_16060	COG2207	Transcriptional regulator
EAG14_16065	COG2807	transmembrane transport
EAG14_16075	COG1309	transcriptional regulator
EAG14_16110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAG14_16115	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_16120	COG1999	signal sequence binding
EAG14_16125	COG0109	protoheme IX farnesyltransferase activity
EAG14_16160	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EAG14_16180	COG2226	methyltransferase
EAG14_16185	COG1040	competence protein
EAG14_16195	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAG14_16210	COG0411	ABC transporter
EAG14_16215	COG1132	(ABC) transporter
EAG14_16220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EAG14_16225	COG0583	DNA-binding transcription factor activity
EAG14_16245	COG1280	lysine exporter protein (LysE YggA)
EAG14_16315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EAG14_16320	COG2205	protein histidine kinase activity
EAG14_16330	COG2204	response regulator
EAG14_16360	COG1763	Mo-molybdopterin cofactor biosynthetic process
EAG14_16385	COG0436	Aminotransferase
EAG14_16395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EAG14_16400	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EAG14_16410	COG0305	Participates in initiation and elongation during chromosome replication
EAG14_16415	COG0359	binds to the 23S rRNA
EAG14_16420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EAG14_16430	COG0360	Binds together with S18 to 16S ribosomal RNA
EAG14_16435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EAG14_16440	COG0443	Heat shock 70 kDa protein
EAG14_16445	COG0484	heat shock protein binding
EAG14_16450	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EAG14_16460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EAG14_16470	COG0066	3-isopropylmalate dehydratase activity
EAG14_16475	COG0473	3-isopropylmalate dehydrogenase activity
EAG14_16480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAG14_16490	COG0101	tRNA pseudouridine synthase activity
EAG14_16495	COG0135	phosphoribosylanthranilate isomerase activity
EAG14_16505	COG0159	tryptophan synthase activity
EAG14_16510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EAG14_16515	COG0762	integral membrane protein
EAG14_16545	COG1215	transferase activity, transferring glycosyl groups
EAG14_16560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EAG14_16565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EAG14_16570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EAG14_16580	COG1472	Belongs to the glycosyl hydrolase 3 family
EAG14_16585	COG0736	holo-[acyl-carrier-protein] synthase activity
EAG14_16590	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EAG14_16595	COG1381	Involved in DNA repair and RecF pathway recombination
EAG14_16600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EAG14_16605	COG0571	ribonuclease III activity
EAG14_16615	COG0681	Belongs to the peptidase S26 family
EAG14_16620	COG0481	GTPase activity
EAG14_16625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAG14_16650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAG14_16655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAG14_16660	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_16670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EAG14_16675	COG0416	fatty acid biosynthetic process
EAG14_16680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EAG14_16685	COG1399	metal-binding, possibly nucleic acid-binding protein
EAG14_16690	COG0424	maF-like protein
EAG14_16695	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EAG14_16700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EAG14_16700	COG0616	signal peptide processing
EAG14_16725	COG3022	response to hydroperoxide
EAG14_16735	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EAG14_16735	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EAG14_16740	COG0840	transmembrane signaling receptor activity
EAG14_16745	COG0840	transmembrane signaling receptor activity
EAG14_16750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAG14_16755	COG0697	spore germination
EAG14_16760	COG0583	DNA-binding transcription factor activity
EAG14_16795	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_16800	COG0583	DNA-binding transcription factor activity
EAG14_16805	COG2203	Gaf domain
EAG14_16805	COG3706	GGDEF domain
EAG14_16805	COG4251	negative regulation of phosphorylation
EAG14_16805	COG5001	Diguanylate cyclase
EAG14_16825	COG1414	Transcriptional regulator
EAG14_16830	COG3842	ATPase activity
EAG14_16835	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAG14_16840	COG1177	transmembrane transport
EAG14_16855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAG14_16890	COG0840	transmembrane signaling receptor activity
EAG14_16900	COG1595	DNA-templated transcription, initiation
EAG14_16910	COG1304	FMN binding
EAG14_16920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAG14_16945	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_16950	COG0165	Argininosuccinate lyase
EAG14_16955	COG3275	phosphorelay sensor kinase activity
EAG14_16985	COG1178	ABC-type Fe3 transport system permease component
EAG14_16990	COG3842	ATPase activity
EAG14_17000	COG0840	transmembrane signaling receptor activity
EAG14_17020	COG0540	Belongs to the ATCase OTCase family
EAG14_17025	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EAG14_17030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EAG14_17035	COG1678	Uncharacterized ACR, COG1678
EAG14_17040	COG0415	Belongs to the DNA photolyase family
EAG14_17060	COG0835	chemotaxis
EAG14_17075	COG1773	rubredoxin
EAG14_17085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EAG14_17095	COG1414	Transcriptional regulator
EAG14_17100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAG14_17105	COG4654	Cytochrome c, class I
EAG14_17110	COG0138	bifunctional purine biosynthesis protein purh
EAG14_17115	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EAG14_17120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAG14_17135	COG3706	GGDEF domain
EAG14_17140	COG0012	GTP binding
EAG14_17145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAG14_17150	COG1653	transport
EAG14_17155	COG1175	transmembrane transport
EAG14_17160	COG0395	ABC-type sugar transport system, permease component
EAG14_17175	COG0584	glycerophosphoryl diester phosphodiesterase
EAG14_17190	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EAG14_17195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EAG14_17200	COG2890	protein-(glutamine-N5) methyltransferase activity
EAG14_17210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EAG14_17215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EAG14_17220	COG1253	flavin adenine dinucleotide binding
EAG14_17230	COG0442	prolyl-tRNA aminoacylation
EAG14_17235	COG0494	nUDIX hydrolase
EAG14_17240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EAG14_17245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EAG14_17250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EAG14_17255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EAG14_17260	COG0142	geranyltranstransferase activity
EAG14_17275	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EAG14_17280	COG0237	dephospho-CoA kinase activity
EAG14_17285	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EAG14_17290	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EAG14_17295	COG0494	nUDIX hydrolase
EAG14_17305	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EAG14_17310	COG0653	protein targeting
EAG14_17315	COG0739	heme binding
EAG14_17330	COG2969	positive regulation of protein catabolic process
EAG14_17335	COG0625	glutathione transferase activity
EAG14_17340	COG2857	Cytochrome c1
EAG14_17345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EAG14_17360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EAG14_17365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EAG14_17370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAG14_17375	COG0805	protein transport
EAG14_17380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAG14_17385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAG14_17390	COG0537	adenosine 5'-monophosphoramidase activity
EAG14_17405	COG0140	phosphoribosyl-ATP diphosphatase activity
EAG14_17410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EAG14_17415	COG0107	imidazoleglycerol-phosphate synthase activity
EAG14_17420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EAG14_17485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EAG14_17490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EAG14_17495	COG0131	Imidazoleglycerol-phosphate dehydratase
EAG14_17500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EAG14_17515	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EAG14_17520	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EAG14_17525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAG14_17540	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EAG14_17550	COG1560	Kdo2-lipid A biosynthetic process
EAG14_17560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EAG14_17590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EAG14_17595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAG14_17595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EAG14_17600	COG1056	cytidyltransferase-related domain
EAG14_17600	COG1051	belongs to the nudix hydrolase family
EAG14_17605	COG0840	transmembrane signaling receptor activity
EAG14_17610	COG5001	Diguanylate cyclase
EAG14_17625	COG1953	Uracil, thiamine, allantoin
EAG14_17635	COG0493	'glutamate synthase
EAG14_17640	COG1309	transcriptional regulator
EAG14_17655	COG0730	response to heat
EAG14_17660	COG1218	3'(2'),5'-bisphosphate nucleotidase
EAG14_17675	COG0175	sulfate reduction
EAG14_17725	COG3958	Transketolase
EAG14_17730	COG3959	Transketolase, thiamine diphosphate binding domain
EAG14_17745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EAG14_17750	COG3754	Rhamnan synthesis protein F
EAG14_17795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EAG14_17800	COG0459	protein refolding
EAG14_17810	COG1858	cytochrome C peroxidase
EAG14_17825	COG0745	RESPONSE REGULATOR receiver
EAG14_17830	COG0642	Histidine kinase
EAG14_17835	COG0800	Aldolase
EAG14_17860	COG0166	Belongs to the GPI family
EAG14_17870	COG0346	lactoylglutathione lyase activity
EAG14_17875	COG0837	glucose binding
EAG14_17885	COG0395	ABC-type sugar transport system, permease component
EAG14_17915	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAG14_17930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAG14_17935	COG1309	transcriptional regulator
EAG14_17950	COG0737	Belongs to the 5'-nucleotidase family
EAG14_17955	COG4608	Belongs to the ABC transporter superfamily
EAG14_17960	COG0444	Belongs to the ABC transporter superfamily
EAG14_17965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_17970	COG0747	negative chemotaxis
EAG14_17975	COG1473	amidohydrolase
EAG14_17985	COG0747	negative chemotaxis
EAG14_18000	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EAG14_18005	COG1765	OsmC-like protein
EAG14_18010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAG14_18015	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EAG14_18085	COG0840	transmembrane signaling receptor activity
EAG14_18090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EAG14_18095	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EAG14_18100	COG0840	transmembrane signaling receptor activity
EAG14_18105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EAG14_18115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EAG14_18120	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAG14_18125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAG14_18130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EAG14_18135	COG0772	Belongs to the SEDS family
EAG14_18140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EAG14_18145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EAG14_18150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EAG14_18155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAG14_18165	COG3116	cell division
EAG14_18170	COG0275	rRNA processing
EAG14_18175	COG2001	Belongs to the MraZ family
EAG14_18180	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EAG14_18185	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EAG14_18195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EAG14_18200	COG0523	cobalamin synthesis protein
EAG14_18205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EAG14_18210	COG0835	chemotaxis
EAG14_18230	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EAG14_18240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EAG14_18245	COG0625	glutathione transferase activity
EAG14_18250	COG0583	DNA-binding transcription factor activity
EAG14_18255	COG2814	Major facilitator Superfamily
EAG14_18265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_18295	COG4650	regulator
EAG14_18315	COG1690	Belongs to the RtcB family
EAG14_18320	COG3541	Predicted nucleotidyltransferase
EAG14_18325	COG0430	RNA-3'-phosphate cyclase activity
EAG14_18335	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EAG14_18340	COG0840	transmembrane signaling receptor activity
EAG14_18365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAG14_18370	COG1960	acyl-CoA dehydrogenase activity
EAG14_18375	COG1960	acyl-CoA dehydrogenase activity
EAG14_18380	COG0183	Belongs to the thiolase family
EAG14_18385	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_18385	COG1024	Enoyl-CoA hydratase
EAG14_18395	COG0501	Belongs to the peptidase M48B family
EAG14_18405	COG0418	dihydroorotase activity
EAG14_18410	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_18430	COG1126	abc transporter atp-binding protein
EAG14_18435	COG0765	amino acid transport
EAG14_18440	COG0765	amino acid transport
EAG14_18445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_18455	COG0583	DNA-binding transcription factor activity
EAG14_18470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_18475	COG1620	l-lactate permease
EAG14_18480	COG2186	Transcriptional regulator
EAG14_18485	COG1304	FMN binding
EAG14_18490	COG0277	FAD linked oxidase domain protein
EAG14_18500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAG14_18505	COG5265	(ABC) transporter
EAG14_18510	COG1607	acyl-coa hydrolase
EAG14_18520	COG2050	protein possibly involved in aromatic compounds catabolism
EAG14_18525	COG1024	Enoyl-CoA hydratase
EAG14_18540	COG0183	Belongs to the thiolase family
EAG14_18550	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_18550	COG1024	Enoyl-CoA hydratase
EAG14_18560	COG1960	acyl-CoA dehydrogenase activity
EAG14_18570	COG1309	transcriptional regulator
EAG14_18575	COG0642	Histidine kinase
EAG14_18580	COG0745	RESPONSE REGULATOR receiver
EAG14_18585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EAG14_18610	COG0714	Associated with various cellular activities
EAG14_18660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAG14_18700	COG2165	general secretion pathway protein
EAG14_18710	COG2165	general secretion pathway protein
EAG14_18715	COG1459	type II secretion system
EAG14_18720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAG14_18765	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EAG14_18770	COG1652	LysM domain
EAG14_18790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EAG14_18795	COG0751	glycine-tRNA ligase activity
EAG14_18800	COG2329	Antibiotic biosynthesis monooxygenase
EAG14_18805	COG0752	glycyl-tRNA synthetase alpha subunit
EAG14_18815	COG0583	DNA-binding transcription factor activity
EAG14_18830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EAG14_18835	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EAG14_18860	COG1131	(ABC) transporter
EAG14_18880	COG3186	Phenylalanine-4-hydroxylase
EAG14_18890	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_18895	COG1879	ABC-type sugar transport system periplasmic component
EAG14_18900	COG1129	ABC transporter
EAG14_18905	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAG14_18915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAG14_18920	COG1869	D-ribose catabolic process
EAG14_18935	COG1196	nuclear chromosome segregation
EAG14_18935	COG0739	heme binding
EAG14_18935	COG0741	lytic transglycosylase activity
EAG14_18940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EAG14_18960	COG0617	tRNA 3'-terminal CCA addition
EAG14_18970	COG4944	Protein of unknown function (DUF1109)
EAG14_18975	COG1595	DNA-templated transcription, initiation
EAG14_18985	COG3220	belongs to the UPF0276 family
EAG14_19015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_19020	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EAG14_19065	COG0037	tRNA processing
EAG14_19095	COG0632	four-way junction helicase activity
EAG14_19100	COG1702	phosphate starvation-inducible protein PhoH
EAG14_19105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EAG14_19110	COG0477	Major facilitator Superfamily
EAG14_19120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EAG14_19125	COG1845	cytochrome c oxidase, subunit III
EAG14_19130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EAG14_19145	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EAG14_19150	COG0730	response to heat
EAG14_19155	COG1490	D-aminoacyl-tRNA deacylase activity
EAG14_19175	COG0840	transmembrane signaling receptor activity
EAG14_19185	COG0513	Belongs to the DEAD box helicase family
EAG14_19195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAG14_19200	COG3706	GGDEF domain
EAG14_19205	COG1131	(ABC) transporter
EAG14_19210	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EAG14_19215	COG0842	Transport permease protein
EAG14_19230	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_19235	COG0642	Histidine kinase
EAG14_19240	COG0745	RESPONSE REGULATOR receiver
EAG14_19255	COG1846	Transcriptional regulator
EAG14_19260	COG1764	response to oxidative stress
EAG14_19270	COG2815	serine threonine protein kinase
EAG14_19270	COG0515	serine threonine protein kinase
EAG14_19280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAG14_19300	COG2205	protein histidine kinase activity
EAG14_19300	COG4999	Histidine kinase
EAG14_19300	COG3437	response regulator, receiver
EAG14_19300	COG3850	Histidine kinase
EAG14_19320	COG0326	Molecular chaperone. Has ATPase activity
EAG14_19330	COG1187	pseudouridine synthase activity
EAG14_19355	COG0840	transmembrane signaling receptor activity
EAG14_19360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAG14_19370	COG3409	Peptidoglycan-binding domain 1 protein
EAG14_19370	COG3267	Type II secretory pathway component ExeA
EAG14_19385	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAG14_19390	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAG14_19415	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_19425	COG0697	spore germination
EAG14_19445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAG14_19470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAG14_19480	COG0473	3-isopropylmalate dehydrogenase activity
EAG14_19505	COG2818	Glycosylase
EAG14_19520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAG14_19545	COG1473	amidohydrolase
EAG14_19570	COG0596	Alpha beta hydrolase
EAG14_19615	COG3945	hemerythrin HHE cation binding domain
EAG14_19635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAG14_19640	COG0288	reversible hydration of carbon dioxide
EAG14_19650	COG2181	nitrate reductase activity
EAG14_19655	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EAG14_19660	COG1140	nitrate reductase beta subunit
EAG14_19670	COG2223	nitrite transmembrane transporter activity
EAG14_19680	COG2197	response regulator
EAG14_19685	COG4585	Histidine kinase
EAG14_19700	COG0583	DNA-binding transcription factor activity
EAG14_19715	COG0277	FAD linked oxidase domain protein
EAG14_19720	COG1380	Effector of murein hydrolase LrgA
EAG14_19725	COG1346	cytolysis
EAG14_19730	COG2733	membrane
EAG14_19745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EAG14_19755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAG14_19765	COG2084	Dehydrogenase
EAG14_19770	COG2823	Periplasmic or secreted lipoprotein
EAG14_19775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EAG14_19780	COG0792	nuclease activity
EAG14_19785	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EAG14_19790	COG0443	Heat shock 70 kDa protein
EAG14_19855	COG0582	viral genome integration into host DNA
EAG14_19865	COG2204	response regulator
EAG14_19880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EAG14_19880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EAG14_19890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EAG14_19895	COG0085	RNA polymerase activity
EAG14_19900	COG0222	ribosome binding
EAG14_19905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EAG14_19910	COG0081	regulation of translation
EAG14_19915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EAG14_19925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EAG14_19935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EAG14_19965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_19975	COG1538	Outer membrane efflux protein
EAG14_20000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EAG14_20005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EAG14_20010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EAG14_20015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EAG14_20020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EAG14_20025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EAG14_20035	COG0356	it plays a direct role in the translocation of protons across the membrane
EAG14_20045	COG2921	Belongs to the UPF0250 family
EAG14_20050	COG0321	lipoyl(octanoyl) transferase activity
EAG14_20055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EAG14_20060	COG0662	Cupin 2, conserved barrel domain protein
EAG14_20060	COG2207	Transcriptional regulator
EAG14_20075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAG14_20080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAG14_20100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EAG14_20120	COG0678	peroxiredoxin activity
EAG14_20125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EAG14_20130	COG0255	Belongs to the universal ribosomal protein uL29 family
EAG14_20135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EAG14_20140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EAG14_20145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EAG14_20150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EAG14_20155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EAG14_20160	COG0089	rRNA binding
EAG14_20165	COG0088	Forms part of the polypeptide exit tunnel
EAG14_20170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EAG14_20175	COG0051	transcription antitermination factor activity, RNA binding
EAG14_20180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EAG14_20185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EAG14_20190	COG0049	tRNA binding
EAG14_20195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EAG14_20200	COG1686	Belongs to the peptidase S11 family
EAG14_20205	COG2945	thiolester hydrolase activity
EAG14_20230	COG0598	Magnesium transport protein CorA
EAG14_20235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EAG14_20235	COG0519	Catalyzes the synthesis of GMP from XMP
EAG14_20240	COG0840	transmembrane signaling receptor activity
EAG14_20255	COG0412	Dienelactone hydrolase
EAG14_20260	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_20265	COG2095	MarC family integral membrane protein
EAG14_20270	COG0745	RESPONSE REGULATOR receiver
EAG14_20275	COG2205	protein histidine kinase activity
EAG14_20280	COG4452	Inner membrane protein CreD
EAG14_20300	COG3237	CsbD-like
EAG14_20330	COG0583	DNA-binding transcription factor activity
EAG14_20355	COG1127	ABC transporter
EAG14_20360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EAG14_20385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_20390	COG0765	amino acid transport
EAG14_20415	COG0768	penicillin binding
EAG14_20430	COG1077	Cell shape determining protein MreB Mrl
EAG14_20435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAG14_20440	COG0154	amidase activity
EAG14_20445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAG14_20455	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EAG14_20460	COG0708	Exodeoxyribonuclease III
EAG14_20465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_20470	COG4774	siderophore transport
EAG14_20480	COG0471	metal ion transport
EAG14_20485	COG0039	L-malate dehydrogenase activity
EAG14_20510	COG3706	GGDEF domain
EAG14_20510	COG0745	RESPONSE REGULATOR receiver
EAG14_20520	COG2211	Major facilitator Superfamily
EAG14_20525	COG0745	RESPONSE REGULATOR receiver
EAG14_20535	COG0477	Major facilitator Superfamily
EAG14_20550	COG0438	transferase activity, transferring glycosyl groups
EAG14_20550	COG4641	Protein conserved in bacteria
EAG14_20600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAG14_20605	COG0625	glutathione transferase activity
EAG14_20610	COG0747	negative chemotaxis
EAG14_20660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAG14_20665	COG0477	Major facilitator Superfamily
EAG14_20675	COG0386	Belongs to the glutathione peroxidase family
EAG14_20695	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EAG14_20700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EAG14_20705	COG0247	lactate metabolic process
EAG14_20715	COG0277	FAD linked oxidase domain protein
EAG14_20720	COG0004	ammonium transporteR
EAG14_20725	COG0347	Belongs to the P(II) protein family
EAG14_20745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EAG14_20780	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_20785	COG0583	DNA-binding transcription factor activity
EAG14_20805	COG1024	Enoyl-CoA hydratase
EAG14_20845	COG0348	domain, Protein
EAG14_20890	COG0683	leucine binding
EAG14_20910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EAG14_20955	COG0251	oxidation-reduction process
EAG14_20975	COG1410	methionine synthase
EAG14_20975	COG0646	methionine synthase
EAG14_20995	COG0411	ABC transporter
EAG14_21020	COG5002	protein histidine kinase activity
EAG14_21020	COG2198	Histidine kinase
EAG14_21020	COG0784	Response regulator, receiver
EAG14_21045	COG2326	polyphosphate kinase activity
EAG14_21065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAG14_21105	COG0037	tRNA processing
EAG14_21155	COG1309	transcriptional regulator
EAG14_21165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAG14_21170	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EAG14_21175	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EAG14_21210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAG14_21230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAG14_21245	COG1289	transmembrane transporter activity
EAG14_21250	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EAG14_21260	COG0850	regulation of cytokinetic process
EAG14_21275	COG1183	phosphatidylcholine synthase activity
EAG14_21280	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_21290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAG14_21305	COG0501	Belongs to the peptidase M48B family
EAG14_21310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAG14_21330	COG2233	PERMEase
EAG14_21340	COG0683	leucine binding
EAG14_21350	COG2050	protein possibly involved in aromatic compounds catabolism
EAG14_21380	COG2096	Adenosyltransferase
EAG14_21395	COG1126	abc transporter atp-binding protein
EAG14_21425	COG0277	FAD linked oxidase domain protein
EAG14_21460	COG0640	Transcriptional regulator
EAG14_21470	COG0747	negative chemotaxis
EAG14_21515	COG2203	Gaf domain
EAG14_21515	COG4251	negative regulation of phosphorylation
EAG14_21515	COG3706	GGDEF domain
EAG14_21515	COG5001	Diguanylate cyclase
EAG14_21525	COG1136	(ABC) transporter
EAG14_21525	COG0577	efflux transmembrane transporter activity
EAG14_21530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_21565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAG14_21570	COG1522	sequence-specific DNA binding
EAG14_21585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_21600	COG2040	homocysteine
EAG14_21650	COG4794	Type iii secretion
EAG14_21655	COG4790	Type iii secretion
EAG14_21715	COG4789	Type iii secretion
EAG14_21720	COG1196	nuclear chromosome segregation
EAG14_21720	COG0741	lytic transglycosylase activity
EAG14_21720	COG0739	heme binding
EAG14_21725	COG4792	protein secretion
EAG14_21745	COG3411	Ferredoxin
EAG14_21780	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EAG14_21840	COG1475	DNA binding
EAG14_21860	COG1192	Involved in chromosome partitioning
EAG14_21870	COG0357	Ribosomal RNA small subunit methyltransferase G
EAG14_21875	COG0445	tRNA wobble uridine modification
EAG14_21890	COG0840	transmembrane signaling receptor activity
EAG14_21895	COG1595	DNA-templated transcription, initiation
EAG14_21900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAG14_21915	COG1902	pentaerythritol trinitrate reductase activity
EAG14_21930	COG2217	Heavy metal translocating P-type atpase
EAG14_21940	COG0789	Transcriptional regulator
EAG14_21950	COG2974	May be involved in recombination
EAG14_21965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAG14_21970	COG0791	NLP P60 protein
EAG14_21975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAG14_21985	COG2176	DNA-directed DNA polymerase activity
EAG14_21995	COG2234	aminopeptidase activity
EAG14_22000	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EAG14_22005	COG2824	Alkylphosphonate utilization operon protein PhnA
EAG14_22010	COG1199	ATP-dependent helicase activity
EAG14_22025	COG2203	Gaf domain
EAG14_22025	COG2199	diguanylate cyclase activity
EAG14_22030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAG14_22120	COG1475	DNA binding
EAG14_22160	COG0732	type I restriction modification DNA specificity domain
EAG14_22190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EAG14_22195	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EAG14_22200	COG0594	ribonuclease P activity
EAG14_22205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EAG14_22210	COG0706	membrane insertase activity
EAG14_22215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EAG14_22255	COG0747	negative chemotaxis
EAG14_22265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_22270	COG4608	Belongs to the ABC transporter superfamily
EAG14_22275	COG0444	Belongs to the ABC transporter superfamily
EAG14_22280	COG0154	amidase activity
EAG14_22290	COG0281	malic enzyme
EAG14_22290	COG0280	phosphate acetyltransferase
EAG14_22305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EAG14_22310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAG14_22315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EAG14_22325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EAG14_22330	COG3706	GGDEF domain
EAG14_22365	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_22375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAG14_22380	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EAG14_22395	COG2197	response regulator
EAG14_22425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EAG14_22430	COG2137	regulation of response to DNA damage stimulus
EAG14_22435	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EAG14_22440	COG0045	succinate-CoA ligase (ADP-forming) activity
EAG14_22445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAG14_22455	COG0631	protein serine/threonine phosphatase activity
EAG14_22475	COG4969	Belongs to the N-Me-Phe pilin family
EAG14_22480	COG4969	Belongs to the N-Me-Phe pilin family
EAG14_22495	COG0315	cyclic pyranopterin monophosphate synthase activity
EAG14_22500	COG4783	chaperone-mediated protein folding
EAG14_22505	COG1950	PFAM Membrane protein of
EAG14_22520	COG0861	Integral membrane protein TerC family