locus-tag	class	description
C380_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C380_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C380_00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C380_00030	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_00055	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C380_00060	ENOG4105E0F	Histidine kinase
C380_00075	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
C380_00085	ENOG4105D6E	homoserine dehydrogenase
C380_00110	ENOG410630P	Transcriptional regulator
C380_00115	ENOG4108Z0R	Transferase
C380_00120	ENOG410620I	Diguanylate cyclase
C380_00150	ENOG4105DVT	helicase
C380_00155	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
C380_00180	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C380_00205	ENOG4105CHP	RNA polymerase
C380_00225	ENOG4105GRZ	Ycii-related protein
C380_00230	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C380_00235	ENOG4105K4H	Nlp p60 protein
C380_00240	ENOG4108Z9W	Outer membrane porin
C380_00255	ENOG4105RD8	TRAP dicarboxylate transporter
C380_00260	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_00270	ENOG410811B	TRANSCRIPTIONal
C380_00275	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C380_00290	ENOG4105BZU	Histidine kinase
C380_00300	ENOG4105DH7	May be involved in recombination (By similarity)
C380_00305	ENOG4108NH8	Cation transport protein
C380_00320	ENOG4108UKI	Enoyl-CoA hydratase
C380_00325	ENOG4108IQE	Amp-dependent synthetase and ligase
C380_00330	ENOG4108IV0	ABC, transporter
C380_00350	ENOG4105C0Z	ABC transporter
C380_00405	ENOG4105C59	p-type ATPase
C380_00410	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_00420	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C380_00430	ENOG4108K3A	Glutathione S-transferase
C380_00435	ENOG4105MP9	class II Aldolase
C380_00440	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
C380_00445	ENOG4108KPJ	rna polymerase sigma factor
C380_00450	ENOG4105KRS	Proteinase inhibitor
C380_00470	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C380_00480	ENOG4107QJE	Chromosome Partitioning Protein
C380_00500	ENOG4105FA0	parb-like partition protein
C380_00575	ENOG4105E9K	Isocitrate dehydrogenase
C380_00585	ENOG4107QRT	dEAD DEAH box helicase
C380_00590	ENOG4107T0X	DNA ligase
C380_00595	ENOG4107T0X	DNA ligase
C380_00605	ENOG4108J59	Extracellular solute-binding protein, family 5
C380_00610	ENOG4105KK4	UPF0060 membrane protein
C380_00615	ENOG4108ZHR	arsR family transcriptional regulator
C380_00640	ENOG4105CQB	FAD linked oxidase domain protein
C380_00650	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C380_00655	ENOG4105EBR	Carboxylesterase
C380_00680	ENOG4105E5Q	amino acid AbC transporter
C380_00685	ENOG4105E5Q	amino acid AbC transporter
C380_00690	ENOG4105CDA	abc transporter atp-binding protein
C380_00705	ENOG4108WBT	adenosyltransferase
C380_00710	ENOG4105KA0	thioesterase Superfamily protein
C380_00730	ENOG4105C2W	permease
C380_00765	ENOG4105C94	Transporter
C380_00770	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C380_00780	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_00785	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C380_00795	ENOG4105ETT	transcriptional Regulator, LysR family
C380_00800	ENOG4105BZU	Histidine kinase
C380_00810	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
C380_00815	ENOG4107QMS	site-determining protein
C380_00820	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
C380_00825	ENOG4105EM2	membrane
C380_00845	ENOG41080C8	DUF218 domain
C380_00855	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C380_00860	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
C380_00900	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
C380_00905	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C380_00915	ENOG4105C7B	Threonine dehydratase
C380_00920	ENOG4108JUA	Transcriptional regulator
C380_00935	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C380_00955	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C380_00960	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
C380_00965	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_00970	ENOG4105CXG	d-lactate dehydrogenase
C380_00990	ENOG4105C3R	Methionine synthase
C380_00995	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
C380_01000	ENOG4105CFP	Peptidase U32
C380_01020	ENOG4105CT4	transporter
C380_01030	ENOG4105D82	Glutamate dehydrogenase
C380_01045	ENOG4105CSR	polyphosphate kinase 2
C380_01075	ENOG4105C3R	Methionine synthase
C380_01080	ENOG4108UQ8	endoribonuclease L-psp
C380_01090	ENOG4105BZU	Histidine kinase
C380_01095	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C380_01110	ENOG4105CHR	reductase
C380_01115	ENOG4107S2Z	UPF0761 membrane protein
C380_01130	ENOG4108W9H	Tetr family transcriptional regulator
C380_01135	ENOG4105DP0	ferredoxin-NADP reductase
C380_01140	ENOG4108Z4U	Ferredoxin
C380_01175	ENOG4105C0Z	ABC transporter
C380_01180	ENOG4108IV0	ABC, transporter
C380_01190	ENOG4108XHQ	(2Fe-2S)-binding domain protein
C380_01195	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
C380_01220	ENOG4105F7P	transcriptional regulator AsnC family
C380_01255	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
C380_01265	ENOG4105CSU	acyl-Coa dehydrogenase
C380_01285	ENOG4105E9F	Enoyl-CoA hydratase
C380_01315	ENOG4108JJA	ABC, transporter
C380_01350	ENOG4105DFG	type I secretion outer membrane protein
C380_01355	ENOG4105C0P	Mg chelatase subunit ChlI
C380_01365	ENOG4108YZA	Nitrogen regulatory protein pii
C380_01370	ENOG4105BZU	Histidine kinase
C380_01375	ENOG4105EU8	FAD linked oxidase domain protein
C380_01385	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C380_01395	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
C380_01415	ENOG4108NEV	two component transcriptional regulator, LytTR family
C380_01430	ENOG4108V06	Glutathione peroxidase
C380_01440	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
C380_01445	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C380_01475	ENOG4105DEF	Extracellular solute-binding protein, family 5
C380_01480	ENOG4108RXX	maleylacetoacetate isomerase
C380_01485	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C380_01495	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C380_01505	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C380_01515	ENOG4106WTF	Glycosyl transferase, family 2
C380_01520	ENOG4105PF3	O-Antigen polymerase
C380_01535	ENOG4105EGI	Transcriptional regulator
C380_01540	ENOG4105CBP	Major Facilitator
C380_01545	ENOG4105E0F	Histidine kinase
C380_01550	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C380_01555	ENOG4105EYM	Major Facilitator superfamily
C380_01560	ENOG4105ERG	peptidase m48, ste24p
C380_01565	ENOG4105C5X	domain protein
C380_01570	ENOG4107SDU	Methyl-accepting chemotaxis
C380_01590	ENOG4107QHF	type ii secretion system protein e
C380_01595	ENOG4105CGK	Exodeoxyribonuclease III
C380_01600	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C380_01610	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C380_01615	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C380_01620	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C380_01625	ENOG4105DFF	Rod shape-determining protein mreb
C380_01630	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C380_01635	ENOG4105VQ7	Rod shape-determining protein MreD
C380_01640	ENOG4105CJN	penicillin-binding protein
C380_01655	ENOG4105E5Q	amino acid AbC transporter
C380_01660	ENOG4107R0W	ABC transporter
C380_01670	ENOG4105BZU	Histidine kinase
C380_01695	ENOG4105DHJ	ABC, transporter
C380_01710	ENOG4107QN2	dihydrolipoyl dehydrogenase
C380_01725	ENOG4105VDW	Csbd family
C380_01740	ENOG4105BZU	Histidine kinase
C380_01750	ENOG4105CT7	inner membrane cred family protein
C380_01760	ENOG4105EB3	Histidine kinase
C380_01765	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C380_01770	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
C380_01775	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C380_01790	ENOG4105D7N	magnesium and cobalt transport protein CorA
C380_01795	ENOG4105D52	delta-aminolevulinic acid dehydratase
C380_01800	ENOG4108YXA	Membrane
C380_01815	ENOG4105DHZ	alpha beta
C380_01820	ENOG4105DZ1	carboxypeptidase
C380_01825	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C380_01830	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C380_01835	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C380_01840	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C380_01845	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C380_01850	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C380_01855	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C380_01860	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C380_01865	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C380_01870	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C380_01875	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C380_01880	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C380_01885	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C380_01890	ENOG41084PQ	50s ribosomal protein l29
C380_01895	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C380_01920	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C380_01940	ENOG41080Z8	PHOSPHOCARRIER protein
C380_01945	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C380_01960	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C380_01965	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C380_01970	ENOG4108Z43	UPF0250 protein
C380_01980	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
C380_01985	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C380_01990	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C380_01995	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C380_02000	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C380_02005	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C380_02010	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C380_02015	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C380_02060	ENOG4105MPD	Cytochrome
C380_02065	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C380_02070	ENOG4105BZS	acriflavin resistance protein
C380_02075	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C380_02085	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C380_02090	ENOG4105PM1	preprotein translocase subunit SecE
C380_02100	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C380_02105	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C380_02110	ENOG4108VZM	50s ribosomal protein L10
C380_02115	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C380_02120	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C380_02125	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C380_02135	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C380_02145	ENOG4105ES5	Histidine kinase
C380_02175	ENOG4108KU3	Integrase
C380_02190	ENOG4105R8A	Heat shock protein
C380_02195	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
C380_02200	ENOG41082RQ	UPF0102 protein
C380_02205	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
C380_02210	ENOG4105W4M	Transport-associated protein
C380_02215	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C380_02220	ENOG4105CZX	twitching motility protein
C380_02225	ENOG4105IJJ	transcriptional regulator, crp fnr family
C380_02230	ENOG4105CZX	twitching motility protein
C380_02235	ENOG4105DFA	alanine racemase domain protein
C380_02255	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_02260	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
C380_02265	ENOG410829K	Lysine exporter protein (Lyse ygga)
C380_02280	ENOG4106BRA	Membrane
C380_02285	ENOG41067MG	lrgb family
C380_02290	ENOG4105VAW	lrga family
C380_02295	ENOG4105CQB	FAD linked oxidase domain protein
C380_02300	ENOG4108PZW	LysR family Transcriptional regulator
C380_02310	ENOG4105BZU	Histidine kinase
C380_02320	ENOG4105BZU	Histidine kinase
C380_02325	ENOG4105WH1	Two component transcriptional regulator luxr family
C380_02335	ENOG4105DQQ	Major facilitator superfamily MFS_1
C380_02340	ENOG4105CRU	nitrate reductase, alpha subunit
C380_02345	ENOG4108IUE	nitrate reductase beta subunit
C380_02350	ENOG4105R3A	Nitrate reductase
C380_02355	ENOG4105D0D	Nitrate reductase 2, gamma subunit
C380_02360	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C380_02385	ENOG4105NSG	hemerythrin hhe cation binding domain protein
C380_02425	ENOG4105CIS	alcohol dehydrogenase
C380_02435	ENOG4108I6A	alcohol dehydrogenase
C380_02450	ENOG4108J2R	molybdopterin oxidoreductase
C380_02465	ENOG4105CH2	amidohydrolase
C380_02490	ENOG4107S4F	acyltransferase, ws dgat mgat
C380_02500	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C380_02505	ENOG4107QWB	Ornithine cyclodeaminase
C380_02525	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C380_02540	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
C380_02545	ENOG4108TXN	phosphonate metabolism protein
C380_02550	ENOG4105CMD	Transcriptional regulator, GntR family
C380_02555	ENOG4105KQZ	Phosphonate C-P lyase system protein PhnG
C380_02570	ENOG4105FT8	Phosphonate metabolism
C380_02580	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
C380_02585	ENOG4105HRV	phosphonate c-p lyase system protein phnl
C380_02590	ENOG4105FD8	phosphonate metabolism protein PhnM
C380_02595	ENOG4105D5T	phosphonate abc transporter
C380_02600	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
C380_02630	ENOG4105FDR	Membrane
C380_02635	ENOG4105KME	endoribonuclease L-psp
C380_02645	ENOG4105C1G	acyl-Coa dehydrogenase
C380_02650	ENOG4108UKI	Enoyl-CoA hydratase
C380_02665	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C380_02680	ENOG4105DZS	Phenylacetate-CoA ligase
C380_02685	ENOG4108IV0	ABC, transporter
C380_02700	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_02705	ENOG4105C0Z	ABC transporter
C380_02730	ENOG4105IJJ	transcriptional regulator, crp fnr family
C380_02735	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_02750	ENOG4105BZU	Histidine kinase
C380_02755	ENOG4105FE9	pseudouridine synthase
C380_02770	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C380_02785	ENOG4105E27	serine threonine protein kinase
C380_02795	ENOG4105D9P	serine threonine protein kinase
C380_02810	ENOG4108ZHJ	Organic hydroperoxide resistance protein
C380_02815	ENOG4105K56	Transcriptional regulator
C380_02820	ENOG41060WC	Enoyl-CoA hydratase
C380_02825	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C380_02855	ENOG4105BZU	Histidine kinase
C380_02860	ENOG4105WH1	Two component transcriptional regulator luxr family
C380_02880	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
C380_02890	ENOG4105WH9	RNA polymerase
C380_02900	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
C380_02915	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C380_02920	ENOG4108JUA	Transcriptional regulator
C380_02935	ENOG4108IG5	Transcriptional regulator
C380_02940	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
C380_02945	ENOG4105BZU	Histidine kinase
C380_02950	ENOG4105CJ1	ABC, transporter
C380_02955	ENOG4105MIR	Phenylalanine 4-monooxygenase
C380_02970	ENOG4107IFA	Lipase (EC 3.1.1.3)
C380_02975	ENOG4108XM1	transcriptional regulator AsnC family
C380_02985	ENOG4108JU5	Magnesium and cobalt efflux protein
C380_02990	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
C380_02995	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
C380_03015	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
C380_03020	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
C380_03025	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
C380_03045	ENOG4109066	lysm domain bon superfamily protein
C380_03050	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
C380_03070	ENOG4105PDP	Short chain dehydrogenase
C380_03080	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
C380_03085	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
C380_03090	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
C380_03105	ENOG4105EY8	ABC transporter
C380_03115	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C380_03135	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
C380_03150	ENOG4107RJ7	Glycosyl transferase (Group 1
C380_03160	ENOG4108YSP	acyltransferase 3
C380_03185	ENOG4105CPF	Cell wall formation (By similarity)
C380_03195	ENOG4105CPK	Glycosyl transferase (Group 1
C380_03215	ENOG4108JJ6	Type I secretion system ATPase
C380_03220	ENOG4108JJ6	Type I secretion system ATPase
C380_03225	ENOG4107QZV	Type I secretion membrane fusion protein
C380_03230	ENOG4105DFG	type I secretion outer membrane protein
C380_03240	ENOG4105CAS	nag kinase
C380_03245	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C380_03255	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
C380_03265	ENOG4105CSU	acyl-Coa dehydrogenase
C380_03285	ENOG4105CHU	acetyl-coa acetyltransferase
C380_03300	ENOG4105E39	Enoyl-CoA hydratase
C380_03310	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
C380_03315	ENOG4107QX3	carboxylase
C380_03320	ENOG4105F1N	DNA alkylation repair
C380_03325	ENOG4105C1G	acyl-Coa dehydrogenase
C380_03330	ENOG4105E39	Enoyl-CoA hydratase
C380_03340	ENOG4105C1G	acyl-Coa dehydrogenase
C380_03360	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C380_03365	ENOG4105CHU	acetyl-coa acetyltransferase
C380_03375	ENOG4105C1G	acyl-Coa dehydrogenase
C380_03385	ENOG4108IQE	Amp-dependent synthetase and ligase
C380_03390	ENOG4108IV0	ABC, transporter
C380_03395	ENOG4105C0Z	ABC transporter
C380_03405	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_03410	ENOG4106YT9	Enoyl-CoA hydratase
C380_03415	ENOG4108VUY	thioesterase Superfamily protein
C380_03425	ENOG4105NAU	thioesterase Superfamily protein
C380_03430	ENOG4108JJ7	ABC transporter
C380_03435	ENOG4105C5I	Dehydrogenase
C380_03445	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C380_03450	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_03460	ENOG4107YNJ	LysR family Transcriptional regulator
C380_03465	ENOG4107RP9	extracellular solute-binding protein, family 3
C380_03470	ENOG4107RP9	extracellular solute-binding protein, family 3
C380_03475	ENOG4105EAD	ABC transporter
C380_03480	ENOG4105DRP	amino acid AbC transporter
C380_03485	ENOG4105CDA	abc transporter atp-binding protein
C380_03505	ENOG4105EKE	dihydroorotase
C380_03515	ENOG4105D0M	Protease HtpX homolog
C380_03520	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_03525	ENOG4107QPK	)-transporter
C380_03545	ENOG4105DZ0	fad dependent oxidoreductase
C380_03550	ENOG4107UXM	Membrane
C380_03555	ENOG4105DZQ	phospholipase D Transphosphatidylase
C380_03560	ENOG4105X23	Endonuclease Exonuclease phosphatase
C380_03575	ENOG410756H	nucleotidyltransferase
C380_03580	ENOG4105E0Y	RtcB Protein
C380_03600	ENOG4105CYB	regulatoR
C380_03610	ENOG4108M3P	Membrane
C380_03620	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C380_03625	ENOG4105F27	Major Facilitator
C380_03630	ENOG4105HEI	LysR family (Transcriptional regulator
C380_03640	ENOG4105CYM	Glutathione S-transferase
C380_03645	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C380_03655	ENOG4108J6E	Pfam:Phage_integr_N
C380_03660	ENOG4105C3F	Signal peptidase i
C380_03665	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_03670	ENOG4108V3W	Chemotaxis protein, CheW
C380_03680	ENOG4105CKI	cobalamin synthesis protein
C380_03685	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C380_03695	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
C380_03700	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
C380_03705	ENOG4108V6E	Cell division protein mraZ
C380_03710	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C380_03725	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C380_03730	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
C380_03735	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C380_03740	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C380_03745	ENOG4105CNI	cell division protein FtsW
C380_03750	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C380_03755	ENOG4105DFU	Cell wall formation (By similarity)
C380_03760	ENOG4105CPF	Cell wall formation (By similarity)
C380_03765	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
C380_03770	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C380_03775	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C380_03780	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_03785	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C380_03795	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
C380_03805	ENOG4107QHF	type ii secretion system protein e
C380_03810	ENOG4105GVR	general secretion pathway protein D
C380_03835	ENOG4108WWZ	General secretion pathway protein J
C380_03850	ENOG4108VAU	general secretion pathway protein G
C380_03865	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
C380_03870	ENOG4105C7B	Threonine dehydratase
C380_03875	ENOG4108UKZ	OsmC family
C380_03880	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
C380_03885	ENOG4108Z9W	Outer membrane porin
C380_03890	ENOG4105DEF	Extracellular solute-binding protein, family 5
C380_03895	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C380_03900	ENOG4105CH2	amidohydrolase
C380_03915	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C380_03920	ENOG4105C3U	ABC transporter
C380_03925	ENOG4108JQ7	(ABC) transporter
C380_03930	ENOG4105CBN	LysR family transcriptional regulator
C380_03935	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C380_03940	ENOG4105CHU	acetyl-coa acetyltransferase
C380_03945	ENOG4105CC9	acyl-Coa dehydrogenase
C380_03950	ENOG4105C1G	acyl-Coa dehydrogenase
C380_03955	ENOG4108UKI	Enoyl-CoA hydratase
C380_03960	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C380_03975	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_03980	ENOG4105BZJ	Electron transfer flavoprotein
C380_03985	ENOG4105C10	Electron transfer flavoprotein
C380_04000	ENOG4105C4Y	ABC transporter
C380_04005	ENOG4107RCV	ABC transporter, permease
C380_04015	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C380_04020	ENOG4105DHQ	Histidine kinase
C380_04025	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C380_04040	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
C380_04045	ENOG4105DRS	transport system, permease
C380_04050	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C380_04055	ENOG4105CHC	glucokinase (EC 2.7.1.2)
C380_04060	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
C380_04065	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C380_04070	ENOG4107QP8	phosphohexose isomerase
C380_04090	ENOG4105C01	Dihydroxy-acid dehydratase
C380_04095	ENOG4108UHU	Aldolase
C380_04105	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C380_04110	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C380_04115	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C380_04120	ENOG4105C5Q	Transcriptional regulator
C380_04125	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C380_04130	ENOG4107WT5	transcriptional regulator (NifA
C380_04135	ENOG4108R86	Transcriptional regulator
C380_04140	ENOG4105BZ8	glutamate synthase
C380_04145	ENOG4107SJI	Dehydrogenase
C380_04150	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
C380_04155	ENOG4105CD3	dihydroorotase
C380_04160	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
C380_04175	ENOG4107RH7	Nicotinate phosphoribosyltransferase
C380_04190	ENOG4105BZU	Histidine kinase
C380_04205	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C380_04215	ENOG4105D1S	lipid A biosynthesis
C380_04225	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C380_04235	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
C380_04240	ENOG4105CRE	cytochrome C
C380_04245	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
C380_04250	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
C380_04265	ENOG4105XQ6	frataxin-like protein
C380_04270	ENOG4108JQC	penicillin-binding protein 1A
C380_04305	ENOG4105D49	3-dehydroquinate synthase
C380_04310	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
C380_04340	ENOG4105DHJ	ABC, transporter
C380_04345	ENOG4105CY3	ABC transporter, permease
C380_04350	ENOG4107PE3	Mammalian cell entry related domain protein
C380_04370	ENOG4105DA5	(ABC) transporter
C380_04375	ENOG4105E3A	(ABC) transporter
C380_04380	ENOG4105VFK	BolA family
C380_04385	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C380_04390	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C380_04415	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C380_04420	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C380_04425	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C380_04430	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C380_04435	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C380_04440	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C380_04445	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
C380_04460	ENOG4105K59	histidine triad (HIT) protein
C380_04465	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C380_04470	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C380_04475	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C380_04480	ENOG4105C0H	protease
C380_04485	ENOG4107QNR	UPF0135 protein
C380_04490	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C380_04495	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C380_04500	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C380_04505	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C380_04510	ENOG4105EIX	cytochrome c1
C380_04515	ENOG4107MKT	Stringent starvation protein a
C380_04520	ENOG4105KB2	stringent starvation protein b
C380_04530	ENOG4105DR5	peptidase
C380_04535	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C380_04540	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C380_04550	ENOG4105M6F	mutator MutT protein
C380_04555	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
C380_04560	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
C380_04565	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C380_04580	ENOG4107QHF	type ii secretion system protein e
C380_04585	ENOG4105EAH	synthase
C380_04590	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C380_04595	ENOG4105K46	50S ribosomal protein l27
C380_04600	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C380_04605	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C380_04610	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C380_04615	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C380_04620	ENOG4105E4C	Lytic transglycosylase catalytic
C380_04625	ENOG4105C37	(CBS) domain
C380_04630	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C380_04640	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C380_04645	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C380_04650	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C380_04665	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
C380_04675	ENOG4108IJ9	(ABC) transporter
C380_04690	ENOG4105BZ7	extracellular solute-binding protein family 1
C380_04695	ENOG4108JQ1	Dehydrogenase
C380_04715	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C380_04730	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C380_04755	ENOG4105C9M	aspartyl-trna synthetase
C380_04770	ENOG4108VYJ	response regulator receiver protein
C380_04780	ENOG4105DZQ	phospholipase D Transphosphatidylase
C380_04785	ENOG4105EUJ	GTP cyclohydrolase i
C380_04810	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C380_04830	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C380_04835	ENOG4105DEF	Extracellular solute-binding protein, family 5
C380_04840	ENOG4108JQ7	(ABC) transporter
C380_04850	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C380_04855	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C380_04860	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
C380_04865	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C380_04870	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C380_04875	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C380_04880	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C380_04885	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
C380_04890	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
C380_04895	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C380_04905	ENOG4105CEN	a g-specific adenine glycosylase
C380_04910	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C380_04915	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C380_04920	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C380_04925	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C380_04930	ENOG4108RRZ	Transcription elongation factor GreB
C380_04935	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C380_04940	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C380_04945	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C380_04950	ENOG4105DSJ	YicC domain protein
C380_04970	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C380_04975	ENOG4105CSA	Coproporphyrinogen iii oxidase
C380_04985	ENOG4105BZU	Histidine kinase
C380_05020	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
C380_05025	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
C380_05030	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
C380_05035	ENOG4105I4A	GCN5-related N-acetyltransferase
C380_05040	ENOG4105CQM	Urea amidohydrolase subunit alpha
C380_05045	ENOG4105KI2	Urea amidohydrolase subunit beta
C380_05055	ENOG4108YZ9	Urea amidohydrolase subunit gamma
C380_05060	ENOG4105BZU	Histidine kinase
C380_05065	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C380_05095	ENOG4105BZU	Histidine kinase
C380_05110	ENOG4105F27	Major Facilitator
C380_05115	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
C380_05120	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_05125	ENOG4105CNN	ABC, transporter
C380_05130	ENOG4105C0Z	ABC transporter
C380_05135	ENOG4108IV0	ABC, transporter
C380_05140	ENOG4105MH5	phosphoesterase PA-phosphatase related protein
C380_05145	ENOG4105CBD	Diacylglycerol kinase
C380_05155	ENOG4105F8J	Adenylate Guanylate cyclase
C380_05165	ENOG4105CHM	Aminotransferase
C380_05190	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
C380_05200	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C380_05220	ENOG4105KME	endoribonuclease L-psp
C380_05225	ENOG4107TTD	cytosine deaminase
C380_05245	ENOG4108Z6B	deaminase
C380_05275	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
C380_05285	ENOG4105FB2	class II Aldolase
C380_05295	ENOG4105ZXK	Dehydrogenase
C380_05300	ENOG4105C6Z	Gluconate
C380_05305	ENOG4105JXH	GntR family transcriptional regulator
C380_05310	ENOG4105D78	K07001 NTE family protein
C380_05325	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C380_05340	ENOG4105C6K	Malic enzyme
C380_05345	ENOG4105C2W	permease
C380_05350	ENOG4107YCY	Transcriptional regulator
C380_05355	ENOG4105CK2	sodium dicarboxylate symporter
C380_05360	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C380_05365	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C380_05380	ENOG4107YCY	Transcriptional regulator
C380_05385	ENOG4105VT2	5-hydroxyisourate hydrolase
C380_05405	ENOG4105BZU	Histidine kinase
C380_05415	ENOG4108Z9W	Outer membrane porin
C380_05425	ENOG4105BZU	Histidine kinase
C380_05430	ENOG4105C7W	Xanthine dehydrogenase
C380_05445	ENOG4105C2J	ABC transporter
C380_05450	ENOG4105UIB	(ABC) transporter
C380_05470	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C380_05475	ENOG4105K59	histidine triad (HIT) protein
C380_05485	ENOG4107QUY	Guanine deaminase
C380_05495	ENOG4105DHP	deoxycytidine triphosphate deaminase
C380_05505	ENOG4105BZU	Histidine kinase
C380_05515	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
C380_05520	ENOG4105CGZ	zinc metallopeptidase
C380_05525	ENOG4105CSV	Glutaminase
C380_05530	ENOG4108Z18	K06886 hemoglobin
C380_05535	ENOG4108V0P	LemA family
C380_05540	ENOG4105D0M	Protease HtpX homolog
C380_05560	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
C380_05570	ENOG4105W5Q	DNA repair protein (RadC
C380_05575	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
C380_05580	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C380_05590	ENOG4105C7B	Threonine dehydratase
C380_05595	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C380_05640	ENOG4105GR3	Histidine kinase
C380_05650	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C380_05720	ENOG4108IJF	Heavy metal efflux pump, CzcA
C380_05750	ENOG4105W1Y	Transcriptional regulator
C380_05760	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
C380_05765	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C380_05770	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C380_05795	ENOG4108IJF	Heavy metal efflux pump, CzcA
C380_05850	ENOG4107RDB	Major Facilitator
C380_05855	ENOG4107TPS	domain protein
C380_05890	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
C380_05940	ENOG4105HMI	Membrane
C380_05945	ENOG4105DUM	transcriptional regulator, lysR family
C380_05965	ENOG4105C0H	protease
C380_05990	ENOG4108IXY	short-chain dehydrogenase reductase
C380_06010	ENOG4105C5I	Dehydrogenase
C380_06030	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C380_06035	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
C380_06040	ENOG4105CY0	Metallo-Beta-Lactamase
C380_06050	ENOG4105HA9	of methanol dehydrogenase type
C380_06065	ENOG4105C59	p-type ATPase
C380_06070	ENOG4105CSR	polyphosphate kinase 2
C380_06100	ENOG4105F2I	Transposase
C380_06125	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C380_06170	ENOG4105E3B	Multicopper oxidase
C380_06180	ENOG4105F2I	Transposase
C380_06185	ENOG4105DQ6	Transposase
C380_06325	ENOG4105DFP	Integrase
C380_06380	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C380_06385	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
C380_06390	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
C380_06395	ENOG410804D	Sensor Signal Transduction Histidine Kinase
C380_06405	ENOG4108KXV	response regulator
C380_06420	ENOG4105C31	Tryptophanyl-tRNA synthetase
C380_06425	ENOG4108Z4T	Peptidase M50
C380_06430	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_06435	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
C380_06440	ENOG4105DB7	PHP domain protein
C380_06445	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_06455	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C380_06470	ENOG4105D60	lipoprotein releasing system transmembrane protein
C380_06475	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C380_06490	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C380_06495	ENOG4105C0H	protease
C380_06500	ENOG4105EYA	deoxyribonuclease
C380_06515	ENOG4107QHF	type ii secretion system protein e
C380_06540	ENOG4105ERG	peptidase m48, ste24p
C380_06550	ENOG4105CHR	reductase
C380_06560	ENOG4105BZU	Histidine kinase
C380_06565	ENOG4108IPJ	Membrane
C380_06570	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
C380_06580	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
C380_06585	ENOG4105HEI	LysR family (Transcriptional regulator
C380_06590	ENOG4108M0I	Transcriptional regulator
C380_06595	ENOG4105DHU	Bile acid
C380_06600	ENOG4105EAM	Na Pi-cotransporter
C380_06605	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C380_06610	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C380_06615	ENOG4105DTN	riboflavin biosynthesis protein ribF
C380_06630	ENOG4105C1G	acyl-Coa dehydrogenase
C380_06635	ENOG4105D2B	acyl-CoA dehydrogenase
C380_06640	ENOG4108YXG	UPF0502 protein
C380_06645	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C380_06670	ENOG4105W0E	50S ribosomal protein L33
C380_06675	ENOG4105KDC	50s ribosomal protein l28
C380_06680	ENOG4105C3M	thioredoxin reductase
C380_06685	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
C380_06690	ENOG4105CNU	cell division protein FtsK
C380_06695	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
C380_06700	ENOG4105D1H	recombination factor protein RarA
C380_06710	ENOG4105BZU	Histidine kinase
C380_06720	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_06725	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C380_06730	ENOG4105C0Z	ABC transporter
C380_06735	ENOG4108IV0	ABC, transporter
C380_06745	ENOG4107GRR	phosphate transport regulator
C380_06750	ENOG4107QXV	Phosphate transporter
C380_06765	ENOG4105K5M	30s ribosomal protein S16
C380_06770	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C380_06775	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C380_06780	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C380_06790	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
C380_06795	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C380_06800	ENOG41090A4	Pterin carbinolamine dehydratase
C380_06805	ENOG4105D0M	Protease HtpX homolog
C380_06810	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C380_06815	ENOG4105C1J	atp-dependent rna helicase
C380_06825	ENOG4105C2C	drug resistance transporter, Bcr CflA
C380_06830	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C380_06840	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
C380_06850	ENOG4105C4R	Atp-dependent dna helicase
C380_06870	ENOG4105CUV	Homoserine Kinase
C380_06880	ENOG4105C2M	dna polymerase I
C380_06890	ENOG4105CYM	Glutathione S-transferase
C380_06905	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C380_06910	ENOG4107RP9	extracellular solute-binding protein, family 3
C380_06920	ENOG4107RP9	extracellular solute-binding protein, family 3
C380_06935	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
C380_06950	ENOG4108NEV	two component transcriptional regulator, LytTR family
C380_06955	ENOG4108HRK	Histidine kinase
C380_06960	ENOG4105CH7	arginosuccinase
C380_06961	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C380_06975	ENOG4105BZU	Histidine kinase
C380_07000	ENOG4108Z5K	methylglyoxal synthase
C380_07005	ENOG4105BZ4	penicillin-binding protein
C380_07010	ENOG4105BZU	Histidine kinase
C380_07015	ENOG4105DMF	Dehydrogenase
C380_07025	ENOG4105DU6	RNA polymerase
C380_07070	ENOG4105ETT	transcriptional Regulator, LysR family
C380_07075	ENOG4105C26	Dehydrogenase
C380_07090	ENOG4105CHM	Aminotransferase
C380_07095	ENOG4105C7K	acetolactate synthase
C380_07110	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C380_07115	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C380_07125	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
C380_07135	ENOG4105D1Q	UPF0246 protein
C380_07140	ENOG4105C03	ribonuclease
C380_07145	ENOG4105EI2	Pseudouridine synthase
C380_07160	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C380_07165	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
C380_07170	ENOG4108UHJ	MAF-like protein
C380_07175	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
C380_07180	ENOG4105VGS	50s ribosomal protein l32
C380_07185	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
C380_07190	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C380_07195	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C380_07200	ENOG4105CHR	reductase
C380_07205	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C380_07210	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C380_07220	ENOG4105EMN	RNA polymerase sigma factor
C380_07235	ENOG4105C0H	protease
C380_07240	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C380_07245	ENOG4105C3F	Signal peptidase i
C380_07255	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C380_07260	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C380_07265	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
C380_07270	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
C380_07275	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C380_07280	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
C380_07290	ENOG4105BZU	Histidine kinase
C380_07295	ENOG4105CRK	lysyL-tRNA synthetase
C380_07305	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C380_07320	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
C380_07335	ENOG4105CAQ	asparagine synthetase
C380_07340	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C380_07375	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C380_07380	ENOG4105J5G	Transferase hexapeptide repeat containing protein
C380_07385	ENOG4107R5Z	Oxidoreductase domain protein
C380_07390	ENOG4107QQG	Dehydrogenase
C380_07410	ENOG4108VIA	integral membrane protein
C380_07415	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C380_07420	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C380_07425	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C380_07430	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
C380_07435	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C380_07445	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C380_07450	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C380_07455	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C380_07465	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C380_07475	ENOG4105CY0	Metallo-Beta-Lactamase
C380_07480	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C380_07485	ENOG4105CFG	Acts as a chaperone (By similarity)
C380_07490	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C380_07495	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
C380_07505	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C380_07510	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C380_07515	ENOG4105CDU	Replicative dna helicase
C380_07525	ENOG4108IAB	Phoh family
C380_07530	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C380_07540	ENOG4105CHM	Aminotransferase
C380_07550	ENOG4105D6E	homoserine dehydrogenase
C380_07565	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
C380_07570	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C380_07580	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C380_07600	ENOG4108ZAF	Molybdopterin
C380_07610	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C380_07615	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C380_07625	ENOG4105CP7	Triose-phosphate isomerase
C380_07630	ENOG4107EJC	Preprotein translocase subunit SecG
C380_07635	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C380_07640	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C380_07645	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C380_07650	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C380_07655	ENOG4105GKE	subunit e
C380_07660	ENOG4107QIZ	NADH dehydrogenase
C380_07665	ENOG4108IEH	NADH dehydrogenase subunit g
C380_07670	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
C380_07675	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C380_07680	ENOG4105DF2	NADH dehydrogenase subunit j
C380_07685	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C380_07695	ENOG4105C8S	subunit m
C380_07700	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C380_07715	ENOG4105BZ1	(ABC) transporter
C380_07720	ENOG4105C0Z	ABC transporter
C380_07725	ENOG4108IV0	ABC, transporter
C380_07735	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_07750	ENOG4105C6T	cysteine synthase
C380_07770	ENOG4105VN1	Heat shock protein
C380_07775	ENOG4108I0Y	(ABC) transporter
C380_07780	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C380_07785	ENOG4105C2C	drug resistance transporter, Bcr CflA
C380_07800	ENOG4107QHF	type ii secretion system protein e
C380_07805	ENOG4105CZX	twitching motility protein
C380_07810	ENOG4105D82	Glutamate dehydrogenase
C380_07815	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
C380_07825	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C380_07830	ENOG4105DQR	SNARE associated Golgi
C380_07840	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_07850	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C380_07855	ENOG4105K8N	protein family UPF0079, ATPase
C380_07860	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C380_07865	ENOG4108UJV	acyl-CoA thioesterase i
C380_07880	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C380_07895	ENOG4105D58	Diguanylate phosphodiesterase
C380_07900	ENOG4105D58	Diguanylate phosphodiesterase
C380_07905	ENOG4105ED9	Protein of unknown function (DUF455)
C380_07910	ENOG4108Z0R	Transferase
C380_07915	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C380_07930	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C380_07935	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C380_07945	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C380_07950	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C380_07955	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C380_07965	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C380_07975	ENOG4108YZY	peptidylprolyl cis-trans isomerase
C380_07980	ENOG4105EZE	Cupin 4 family protein
C380_07995	ENOG4105Q2H	domain protein
C380_08000	ENOG4105GJM	(LipO)protein
C380_08005	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C380_08020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C380_08025	ENOG4105E4C	Lytic transglycosylase catalytic
C380_08030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C380_08035	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_08055	ENOG4108EC8	DNA internalization-related competence protein ComEC
C380_08075	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
C380_08100	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
C380_08105	ENOG4105CHM	Aminotransferase
C380_08125	ENOG4108Z9W	Outer membrane porin
C380_08160	ENOG4105E0K	tonB-dependent siderophore receptor
C380_08180	ENOG4108UQY	Iron-storage protein
C380_08190	ENOG4108JU3	Alkyl hydroperoxide reductase
C380_08195	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
C380_08200	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
C380_08210	ENOG4107QN1	sodium solute
C380_08220	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C380_08230	ENOG4108W5M	transcriptional regulator
C380_08235	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C380_08240	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C380_08250	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_08260	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C380_08265	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C380_08270	ENOG4107RUE	extracellular solute-binding protein family 1
C380_08275	ENOG4105BZU	Histidine kinase
C380_08280	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_08305	ENOG4108WUH	Transcriptional regulator, TetR family
C380_08310	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
C380_08320	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C380_08325	ENOG4105DGI	Alkaline phosphatase
C380_08330	ENOG4105BZU	Histidine kinase
C380_08340	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
C380_08345	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C380_08350	ENOG4108K5P	(LipO)protein
C380_08355	ENOG4105C34	Pseudouridine synthase
C380_08360	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C380_08365	ENOG4105FE9	pseudouridine synthase
C380_08370	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C380_08375	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C380_08390	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C380_08395	ENOG4105CUT	histidyl-tRNA synthetase
C380_08405	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C380_08410	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C380_08415	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
C380_08420	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C380_08430	ENOG4107QJR	hflk protein
C380_08435	ENOG4105EPW	hflc protein
C380_08445	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
C380_08450	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C380_08465	ENOG4105I08	Pseudouridine synthase
C380_08495	ENOG4105C5F	glutamine synthetase
C380_08505	ENOG4105CUX	Signal transduction histidine kinase
C380_08510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C380_08520	ENOG4105CGK	Exodeoxyribonuclease III
C380_08540	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C380_08570	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C380_08765	ENOG4108TFU	terminase (Small subunit)
C380_08895	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
C380_08905	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C380_08930	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
C380_08935	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C380_08945	ENOG4105DEI	Mannitol dehydrogenase
C380_08950	ENOG41075H3	AraC family transcriptional regulator
C380_08955	ENOG4105CMG	Carbohydrate kinase
C380_08970	ENOG4108DQ3	n-acetylglutamate synthase
C380_08985	ENOG4105CQB	FAD linked oxidase domain protein
C380_08995	ENOG4107S2Z	UPF0761 membrane protein
C380_09005	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C380_09020	ENOG4105BZU	Histidine kinase
C380_09025	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C380_09030	ENOG4107T31	5'-nucleotidase
C380_09040	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C380_09045	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C380_09050	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
C380_09070	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C380_09085	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C380_09090	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C380_09100	ENOG4105CE9	30S ribosomal protein S2
C380_09105	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C380_09110	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C380_09115	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C380_09125	ENOG4105KNE	Phosphatidate cytidylyltransferase
C380_09130	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C380_09135	ENOG4105DZP	Membrane-associated zinc metalloprotease
C380_09140	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C380_09150	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C380_09155	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C380_09160	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C380_09165	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C380_09170	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C380_09185	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C380_09190	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C380_09205	ENOG4105HBR	Rna-binding protein
C380_09210	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
C380_09215	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C380_09220	ENOG4105EEI	dihydropteroate synthase
C380_09225	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C380_09230	ENOG4105BZU	Histidine kinase
C380_09235	ENOG4105BZU	Histidine kinase
C380_09250	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C380_09270	ENOG4105C9X	ppx gppa phosphatase
C380_09275	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
C380_09280	ENOG4105C8U	phosphate abc transporter
C380_09285	ENOG4105E2Z	phosphate ABC transporter (Permease
C380_09290	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C380_09300	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C380_09305	ENOG4105BZU	Histidine kinase
C380_09310	ENOG4107QI1	Mate efflux family protein
C380_09320	ENOG4105NRA	50s ribosomal protein l31 type b
C380_09325	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C380_09330	ENOG4105K63	Thioredoxin
C380_09340	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
C380_09345	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
C380_09350	ENOG4107QMP	dna polymerase iii subunits gamma and tau
C380_09355	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C380_09360	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C380_09380	ENOG4105E9H	Lytic Murein transglycosylase
C380_09385	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C380_09395	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C380_09400	ENOG410624X	efflux transporter, rnd family, mfp subunit
C380_09405	ENOG4105BZS	acriflavin resistance protein
C380_09415	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C380_09425	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
C380_09430	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C380_09515	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
C380_09525	ENOG4105VCQ	rubredoxin
C380_09550	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C380_09555	ENOG4105IFJ	Histidine kinase
C380_09585	ENOG4105F0N	pyrophosphate phospho-hydrolase
C380_09590	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_09600	ENOG4108V3W	Chemotaxis protein, CheW
C380_09605	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_09615	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_09625	ENOG4105C4K	Nad synthetase
C380_09630	ENOG4108YZA	Nitrogen regulatory protein pii
C380_09635	ENOG4108URH	decarboxylase
C380_09640	ENOG41080IJ	Diacylglycerol kinase
C380_09665	ENOG4105C7K	acetolactate synthase
C380_09670	ENOG4108ZP8	Acetolactate synthase small subunit
C380_09675	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C380_09680	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C380_09685	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C380_09690	ENOG41061WM	D-Alanyl-D-Alanine
C380_09695	ENOG4108N16	Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region
C380_09700	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
C380_09705	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
C380_09955	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C380_09970	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C380_09975	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
C380_09980	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C380_09985	ENOG4108ETH	Formylglycinamide ribotide synthetase
C380_10015	ENOG4105CKW	Inner membrane protein yedI
C380_10025	ENOG41067HS	methyltransferase
C380_10040	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
C380_10045	ENOG4105CFP	Peptidase U32
C380_10050	ENOG4105CP9	extracellular ligand-binding receptor
C380_10065	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
C380_10100	ENOG4105C1G	acyl-Coa dehydrogenase
C380_10115	ENOG4108UKI	Enoyl-CoA hydratase
C380_10120	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C380_10130	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C380_10135	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C380_10160	ENOG4105CAY	ferredoxin--nadp reductase
C380_10165	ENOG4108Z4U	Ferredoxin
C380_10170	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
C380_10175	ENOG4105C11	sulfate adenylyltransferase), subunit 2
C380_10195	ENOG4107TSN	permease
C380_10200	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
C380_10205	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
C380_10210	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C380_10215	ENOG4108UZX	fmn reductase
C380_10220	ENOG4105GVF	(ABC) transporter
C380_10225	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
C380_10235	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C380_10240	ENOG4105E2Y	ABC, transporter
C380_10250	ENOG4105NXH	GreA GreB family elongation factor
C380_10260	ENOG4105CPU	Monooxygenase
C380_10265	ENOG4105CPU	Monooxygenase
C380_10270	ENOG4105E2B	Taurine dioxygenase
C380_10280	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
C380_10285	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C380_10295	ENOG4107Z6I	Thiamine biosynthesis protein
C380_10300	ENOG41061MV	Arylsulfatase
C380_10305	ENOG4107R11	Transcriptional regulator
C380_10315	ENOG41063Z6	transcriptional regulator, lysR family
C380_10325	ENOG4105CH7	arginosuccinase
C380_10375	ENOG4105ETX	regulatoR
C380_10435	ENOG4105CXK	mandelate racemase muconate lactonizing
C380_10440	ENOG4108RTU	Aldolase
C380_10445	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
C380_10460	ENOG41062B0	ABC transporter, permease
C380_10465	ENOG4107R9N	ABC transporter
C380_10470	ENOG4105C2J	ABC transporter
C380_10475	ENOG4107RNG	ABC transporter
C380_10485	ENOG4105DFW	ABC transporter
C380_10490	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
C380_10495	ENOG4105C26	Dehydrogenase
C380_10510	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
C380_10540	ENOG4105DND	Transcriptional regulator
C380_10545	ENOG4105EUP	HipA domain protein
C380_10560	ENOG4105EQ0	Major Facilitator superfamily
C380_10570	ENOG4105EQ0	Major Facilitator superfamily
C380_10575	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C380_10580	ENOG4108UMI	ABC transporter, permease
C380_10585	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C380_10605	ENOG4105EJC	lysr family transcriptional regulator
C380_10615	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
C380_10620	ENOG4105VUF	Transcriptional regulator
C380_10635	ENOG4105BZM	domain protein
C380_10650	ENOG4105BZU	Histidine kinase
C380_10675	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
C380_10680	ENOG4105HHA	aminodeoxychorismate lyase
C380_10685	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C380_10690	ENOG4107QRG	dna polymerase iii
C380_10700	ENOG4105F8V	Hydrolase, tatD family
C380_10710	ENOG4105BZ1	(ABC) transporter
C380_10715	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
C380_10720	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C380_10730	ENOG4105CUZ	uba thif-type nad fad binding protein
C380_10790	ENOG4105DH7	May be involved in recombination (By similarity)
C380_10875	ENOG4105YES	addiction module antidote protein
C380_10880	ENOG4105VUH	addiction module killer protein
C380_10900	ENOG4108REF	Sporulation integral membrane protein ytvi
C380_10905	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C380_10910	ENOG4105C7S	Dehydrogenase
C380_10915	ENOG4107QN2	dihydrolipoyl dehydrogenase
C380_10920	ENOG4105D6Z	AFG1 family ATPase
C380_10930	ENOG4108ZF3	Phosphatase
C380_10940	ENOG4105DVT	helicase
C380_10950	ENOG4105C0B	DNA polymerase III (alpha subunit)
C380_10955	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C380_10960	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C380_10965	ENOG41066T0	asmA family
C380_10970	ENOG4105D3G	Pseudouridine synthase
C380_10980	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
C380_10985	ENOG4105F38	ABC transporter, permease
C380_10995	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C380_11000	ENOG4108JPW	Aminotransferase
C380_11005	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C380_11010	ENOG4108WYP	Transcriptional regulator
C380_11015	ENOG41062YB	Trap dicarboxylate transporter, dctp subunit
C380_11020	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_11040	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
C380_11045	ENOG4105CTU	Proline racemase
C380_11050	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C380_11055	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C380_11060	ENOG4105DHT	Metal Dependent Phosphohydrolase
C380_11065	ENOG4105BZU	Histidine kinase
C380_11070	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C380_11075	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
C380_11080	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
C380_11085	ENOG4105EQ1	Transcriptional regulator
C380_11095	ENOG4108VBZ	doxx family
C380_11110	ENOG4105EUB	pirin domain protein
C380_11115	ENOG4105C72	UPF0176 protein
C380_11125	ENOG4105BZU	Histidine kinase
C380_11140	ENOG4105C28	cystathionine
C380_11150	ENOG4108UJV	acyl-CoA thioesterase i
C380_11155	ENOG4108I0Y	(ABC) transporter
C380_11160	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C380_11165	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C380_11220	ENOG4105BZC	d-serine deaminase
C380_11230	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C380_11235	ENOG4105FC8	fad dependent oxidoreductase
C380_11245	ENOG4107QN2	dihydrolipoyl dehydrogenase
C380_11250	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C380_11265	ENOG410645S	MarR family Transcriptional regulator
C380_11270	ENOG4105CCT	upf0313 protein
C380_11285	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
C380_11290	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
C380_11300	ENOG4105CGF	Aromatic amino acid aminotransferase
C380_11305	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C380_11310	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
C380_11315	ENOG4105C3J	Cysteine desulfurase
C380_11320	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
C380_11335	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
C380_11340	ENOG4108ZIT	Ferredoxin, 2FE-2S
C380_11345	ENOG4107RZZ	dna polymerase iii epsilon subunit
C380_11350	ENOG41067B5	Histone deacetylase superfamily protein
C380_11355	ENOG4105D5U	fad dependent oxidoreductase
C380_11375	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C380_11380	ENOG4105E66	phosphoriboisomerase A
C380_11390	ENOG4105DGW	oligopeptidase A
C380_11395	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C380_11400	ENOG4108ZXC	Two component transcriptional regulator, luxr family
C380_11405	ENOG4105BZU	Histidine kinase
C380_11410	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C380_11415	ENOG4107QSN	dihydrolipoamide acetyltransferase
C380_11420	ENOG4107QN2	dihydrolipoyl dehydrogenase
C380_11430	ENOG4105CZK	Aspartate kinase
C380_11440	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
C380_11450	ENOG4105EAB	amino acid AbC transporter
C380_11455	ENOG4105CDA	abc transporter atp-binding protein
C380_11460	ENOG4105E5Q	amino acid AbC transporter
C380_11465	ENOG4105EAD	ABC transporter
C380_11475	ENOG4106UX7	integral membrane protein
C380_11485	ENOG410804X	Transcriptional regulator
C380_11490	ENOG4107VIJ	nudix hydrolase
C380_11495	ENOG4107SQI	penicillin amidase
C380_11500	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
C380_11505	ENOG4105DR4	Methyltransferase
C380_11515	ENOG4105BZU	Histidine kinase
C380_11530	ENOG4105CF1	Alkylated DNA repair protein
C380_11540	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C380_11560	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C380_11590	ENOG4105K4H	Nlp p60 protein
C380_11595	ENOG4105D8V	Glucose sorbosone dehydrogenase
C380_11600	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
C380_11605	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C380_11615	ENOG4105CSH	Transporter
C380_11620	ENOG4105CH2	amidohydrolase
C380_11625	ENOG4105CSV	Glutaminase
C380_11645	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C380_11655	ENOG4105BZU	Histidine kinase
C380_11675	ENOG4107QKV	phosphomannomutase
C380_11685	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
C380_11690	ENOG4105DFG	type I secretion outer membrane protein
C380_11700	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C380_11730	ENOG4105YA8	Transcriptional regulator
C380_11735	ENOG4105FDP	GntR family transcriptional regulator
C380_11740	ENOG4105CP9	extracellular ligand-binding receptor
C380_11745	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_11750	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C380_11755	ENOG4105C0Z	ABC transporter
C380_11760	ENOG4108IV0	ABC, transporter
C380_11770	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C380_11775	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C380_11805	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C380_11815	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C380_11840	ENOG4105UGU	tonB-dependent Receptor
C380_11845	ENOG4105BZU	Histidine kinase
C380_11850	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
C380_11855	ENOG4105E0C	molybdate abc transporter
C380_11860	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
C380_11865	ENOG4105F4R	Transcriptional regulator mode
C380_11880	ENOG4105DHQ	Histidine kinase
C380_11905	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C380_11910	ENOG4107Z3H	Transcriptional regulator, TetR family
C380_11935	ENOG4105DMF	Dehydrogenase
C380_11945	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C380_11950	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C380_11965	ENOG4108UYE	Lactoylglutathione lyase
C380_11995	ENOG4105CHR	reductase
C380_12005	ENOG4107S76	domain protein
C380_12020	ENOG41080HT	Transcriptional regulator, arsr family
C380_12030	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C380_12050	ENOG4105BZU	Histidine kinase
C380_12055	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C380_12060	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
C380_12080	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C380_12085	ENOG4107QX3	carboxylase
C380_12090	ENOG4105DJT	lAO AO transport system ATPase
C380_12100	ENOG4105DRR	Transcriptional regulator, GntR family
C380_12105	ENOG4108IQE	Amp-dependent synthetase and ligase
C380_12115	ENOG4105EW9	transcriptional regulator AsnC family
C380_12140	ENOG4105CAR	Terminase, large subunit
C380_12200	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C380_12210	ENOG4105BZU	Histidine kinase
C380_12225	ENOG4108R3D	Electron transport complex
C380_12230	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_12235	ENOG4105CHM	Aminotransferase
C380_12240	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
C380_12245	ENOG4105CZX	twitching motility protein
C380_12250	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C380_12255	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
C380_12260	ENOG4105C5H	ABC transporter
C380_12265	ENOG4105CHR	reductase
C380_12270	ENOG4105BZU	Histidine kinase
C380_12285	ENOG4105CHU	acetyl-coa acetyltransferase
C380_12290	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
C380_12300	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C380_12330	ENOG4108JQC	penicillin-binding protein 1A
C380_12335	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C380_12345	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
C380_12350	ENOG4105BZU	Histidine kinase
C380_12355	ENOG4105BZU	Histidine kinase
C380_12360	ENOG4105CFF	transcriptional regulator
C380_12370	ENOG4105BZN	citrate synthase
C380_12375	ENOG4108I0Z	Aconitate hydratase
C380_12380	ENOG4105C7F	AcnD-accessory protein PrpF
C380_12390	ENOG4105BZU	Histidine kinase
C380_12405	ENOG4105BZ1	(ABC) transporter
C380_12430	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
C380_12440	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
C380_12450	ENOG4105C5I	Dehydrogenase
C380_12470	ENOG4105DZ2	Transcriptional regulator
C380_12475	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
C380_12480	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C380_12490	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
C380_12495	ENOG4105CW7	secretion protein, HlyD family
C380_12500	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C380_12510	ENOG4105BZU	Histidine kinase
C380_12525	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C380_12540	ENOG4105MSY	salicylate hydroxylase
C380_12565	ENOG4105C26	Dehydrogenase
C380_12575	ENOG4105C1G	acyl-Coa dehydrogenase
C380_12590	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C380_12595	ENOG4105BZU	Histidine kinase
C380_12600	ENOG4105M3Z	response regulator
C380_12605	ENOG4105BZU	Histidine kinase
C380_12625	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C380_12630	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C380_12645	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
C380_12650	ENOG4105W49	UPF0434 protein
C380_12655	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
C380_12660	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C380_12675	ENOG4107RB3	L-asparaginase
C380_12680	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C380_12685	ENOG4105C5I	Dehydrogenase
C380_12715	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C380_12735	ENOG4107R11	Transcriptional regulator
C380_12740	ENOG4105CHM	Aminotransferase
C380_12750	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C380_12755	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C380_12760	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
C380_12765	ENOG4105C08	Histidine kinase
C380_12770	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
C380_12785	ENOG4105C03	ribonuclease
C380_12790	ENOG4108Z03	MAF-like protein
C380_12795	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C380_12800	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
C380_12805	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
C380_12810	ENOG4105C12	Phosphoribosylglycinamide synthetase
C380_12815	ENOG4105CDY	transcriptional regulatory protein
C380_12820	ENOG4105D7A	ATP-binding protein
C380_12830	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C380_12835	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
C380_12855	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C380_12860	ENOG4107TFB	basic membrane
C380_12870	ENOG4108JQ9	ABC transporter
C380_12880	ENOG41083U2	ABC transporter, permease
C380_12895	ENOG4105DZC	cytosine deaminase
C380_12905	ENOG4105CMI	transporter
C380_12910	ENOG4105CJ1	ABC, transporter
C380_12915	ENOG4105D0S	secretion protein (HlyD
C380_12925	ENOG4105BZU	Histidine kinase
C380_12945	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C380_12950	ENOG4105CDY	transcriptional regulatory protein
C380_12960	ENOG4105D9P	serine threonine protein kinase
C380_12965	ENOG4105C28	cystathionine
C380_12970	ENOG4105CJB	Exodeoxyribonuclease I
C380_12975	ENOG4105CVE	Lytic murein transglycosylase
C380_12985	ENOG4105C0B	DNA polymerase III (alpha subunit)
C380_13000	ENOG4108ESY	Metal dependent phosphohydrolase
C380_13010	ENOG4107QNJ	CoA-transferase subunit B
C380_13025	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
C380_13030	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
C380_13060	ENOG4108JQ1	Dehydrogenase
C380_13065	ENOG4105JSC	dimethylmenaquinone methyltransferase
C380_13075	ENOG4105GAK	amidohydrolase 2
C380_13100	ENOG4105BZU	Histidine kinase
C380_13120	ENOG4105CHR	reductase
C380_13125	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
C380_13150	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_13160	ENOG4105CQ7	ATP-dependent helicase
C380_13165	ENOG4105FQP	Beta-lactamase
C380_13175	ENOG4105IU0	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C380_13180	ENOG4108EKC	n-acetylglutamate synthase
C380_13190	ENOG4105ETT	transcriptional Regulator, LysR family
C380_13195	ENOG4105DHT	Metal Dependent Phosphohydrolase
C380_13200	ENOG4105C72	UPF0176 protein
C380_13215	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
C380_13220	ENOG4108IJ6	ABC transporter
C380_13230	ENOG4108I5D	sulfate abc transporter
C380_13235	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C380_13250	ENOG4108WQI	RNA Polymerase
C380_13265	ENOG4105HEI	LysR family (Transcriptional regulator
C380_13270	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C380_13275	ENOG4105BZU	Histidine kinase
C380_13280	ENOG4105D01	(LipO)protein
C380_13330	ENOG4105CSU	acyl-Coa dehydrogenase
C380_13340	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C380_13350	ENOG4105CHR	reductase
C380_13360	ENOG4105CSU	acyl-Coa dehydrogenase
C380_13370	ENOG4105CHU	acetyl-coa acetyltransferase
C380_13375	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C380_13380	ENOG4108IV0	ABC, transporter
C380_13385	ENOG4105C0Z	ABC transporter
C380_13395	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_13405	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_13410	ENOG4105IJJ	transcriptional regulator, crp fnr family
C380_13415	ENOG4105EBR	Carboxylesterase
C380_13420	ENOG4108R6W	Transcriptional regulator, ARAC family
C380_13425	ENOG4105CNG	UPF0061 protein
C380_13430	ENOG4105E0X	reductase
C380_13435	ENOG4107835	probably involved in intracellular septation (By similarity)
C380_13445	ENOG4107TF3	peptidylprolyl cis-trans isomerase
C380_13455	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C380_13460	ENOG4105W87	Cbs domain
C380_13470	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_13480	ENOG4105C0Z	ABC transporter
C380_13485	ENOG4108IV0	ABC, transporter
C380_13510	ENOG4105CI2	imidazolone-5-propionate hydrolase
C380_13515	ENOG41090B9	response to stress
C380_13525	ENOG4105CGP	Urocanate hydratase
C380_13530	ENOG4105C84	Histidine ammonia-lyase
C380_13545	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C380_13555	ENOG41062D9	Histidine kinase
C380_13560	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C380_13575	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C380_13580	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C380_13585	ENOG4105UYK	outer membrane protein a
C380_13590	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C380_13595	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C380_13610	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C380_13615	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C380_13620	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C380_13630	ENOG4105CFV	Tetratricopeptide repeat protein
C380_13640	ENOG4105D65	subunit l
C380_13645	ENOG4108ZE9	Monovalent cation H antiporter subunit C
C380_13650	ENOG4107R4Z	monovalent cation h antiporter subunit d
C380_13655	ENOG4105SC1	monovalent cation H antiporter subunit E
C380_13660	ENOG4105W4C	monovalent cation H antiporter subunit F
C380_13665	ENOG4105KJM	monovalent cation h antiporter subunit g
C380_13690	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_13695	ENOG4107Z6W	Protein CrcB homolog
C380_13710	ENOG4107QSV	RmuC domain protein
C380_13725	ENOG4107RH7	Nicotinate phosphoribosyltransferase
C380_13735	ENOG4105DGU	Histone deacetylase
C380_13740	ENOG4108WFY	phasin family
C380_13755	ENOG4105BZU	Histidine kinase
C380_13760	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C380_13765	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C380_13780	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C380_13785	ENOG4105KUZ	arsenate reductase
C380_13795	ENOG4105NBK	UPF0345 protein
C380_13800	ENOG4105CDH	Citrulline--aspartate ligase
C380_13805	ENOG4105D4A	Cell wall formation (By similarity)
C380_13810	ENOG4108VPT	UPF0234 protein
C380_13815	ENOG4108WIW	Aspartyl protease
C380_13825	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C380_13830	ENOG4108Z66	YbaK ebsC protein
C380_13835	ENOG4107RSM	transcriptional regulator
C380_13850	ENOG4105CPC	Aldo Keto reductase
C380_13855	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
C380_13870	ENOG4107VXZ	Hydrolase
C380_13875	ENOG4105CD8	aminopeptidase N
C380_13880	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C380_13900	ENOG4105C0D	helicase
C380_13915	ENOG4107S1Q	Phosphatase
C380_13925	ENOG4108I5C	dEAD DEAH box helicase
C380_14005	ENOG41067CV	Integrase
C380_14010	ENOG4108KU3	Integrase
C380_14020	ENOG4105F2I	Transposase
C380_14045	ENOG4105DZR	Type I site-specific deoxyribonuclease
C380_14160	ENOG41067CV	Integrase
C380_14180	ENOG4108XDN	Transcriptional regulator
C380_14185	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C380_14190	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C380_14195	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C380_14200	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C380_14205	ENOG4105VJV	50s ribosomal protein L35
C380_14210	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C380_14215	ENOG4105C22	threonyL-tRNA synthetase
C380_14220	ENOG4108I9X	Isocitrate lyase
C380_14235	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
C380_14245	ENOG4105E0K	tonB-dependent siderophore receptor
C380_14250	ENOG4107E2E	PKHD-type hydroxylase
C380_14275	ENOG4105SG9	biopolymer transport protein, ExbD
C380_14285	ENOG4108ZJF	Glcg protein
C380_14290	ENOG4108MN8	Membrane
C380_14300	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C380_14310	ENOG4105EW9	transcriptional regulator AsnC family
C380_14315	ENOG4105C26	Dehydrogenase
C380_14425	ENOG4106NZI	LysR family Transcriptional regulator
C380_14430	ENOG4105C10	Electron transfer flavoprotein
C380_14435	ENOG4105BZJ	Electron transfer flavoprotein
C380_14440	ENOG4105CSU	acyl-Coa dehydrogenase
C380_14445	ENOG4105D2S	major facilitator superfamily
C380_14465	ENOG4105C1G	acyl-Coa dehydrogenase
C380_14475	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_14480	ENOG4105CHU	acetyl-coa acetyltransferase
C380_14485	ENOG4105E39	Enoyl-CoA hydratase
C380_14520	ENOG4107QJE	Chromosome Partitioning Protein
C380_14565	ENOG4105FEQ	ParB domain protein nuclease
C380_14610	ENOG4107YU2	histidine triad (hIT) protein
C380_14620	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C380_14645	ENOG4105DFP	Integrase
C380_14650	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C380_14665	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C380_14675	ENOG4105VDB	UPF0125 protein
C380_14680	ENOG4108Z1B	Cyclase dehydrase
C380_14685	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C380_14705	ENOG4105E39	Enoyl-CoA hydratase
C380_14720	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C380_14725	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C380_14730	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C380_14735	ENOG4105CHV	Transcription elongation factor NusA
C380_14740	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
C380_14745	ENOG4105C0D	helicase
C380_14765	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C380_14830	ENOG4108TFY	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C380_14835	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C380_14850	ENOG4105EJC	lysr family transcriptional regulator
C380_14860	ENOG4105QNF	Outer membrane lipoprotein
C380_14865	ENOG4108JQ5	ABC transporter
C380_14870	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
C380_14875	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
C380_14880	ENOG4105E43	Extracellular solute-binding protein, family 5
C380_14885	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
C380_14900	ENOG4105CXN	decarboxylase
C380_14920	ENOG4105CVR	type I restriction-modification system
C380_14975	ENOG4105BZU	Histidine kinase
C380_14995	ENOG4107R16	Multicopper oxidase
C380_15000	ENOG4105UTB	Blue (Type 1) copper domain protein
C380_15015	ENOG4105KXX	peptidase s58 dmpa
C380_15050	ENOG4105C5H	ABC transporter
C380_15055	ENOG4105C1J	atp-dependent rna helicase
C380_15060	ENOG4105K4T	epimerase
C380_15075	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C380_15085	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
C380_15090	ENOG4105K70	DNA-binding protein
C380_15095	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C380_15100	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C380_15105	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C380_15135	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C380_15140	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C380_15145	ENOG4108M0I	Transcriptional regulator
C380_15155	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C380_15160	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
C380_15165	ENOG4108NVM	synthesis repressor PhaR
C380_15170	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C380_15180	ENOG4105DTD	Dehydrogenase
C380_15190	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C380_15195	ENOG4105E0F	Histidine kinase
C380_15210	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
C380_15215	ENOG4105DIQ	Transcriptional regulator
C380_15220	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C380_15225	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
C380_15230	ENOG4108JA2	transcriptioN-repair coupling factor
C380_15245	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C380_15255	ENOG4105EAC	phosphoserine phosphatase
C380_15265	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
C380_15295	ENOG4105C1J	atp-dependent rna helicase
C380_15315	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_15320	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
C380_15335	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C380_15345	ENOG4107JHD	SlyX family
C380_15350	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C380_15375	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C380_15380	ENOG41080UQ	Transcriptional regulator
C380_15385	ENOG4105CSM	endonuclease III
C380_15390	ENOG41086VY	Fic/DOC family
C380_15405	ENOG4107XBN	GntR Family Transcriptional Regulator
C380_15410	ENOG4105EG2	ABC transporter, permease
C380_15415	ENOG4105F38	ABC transporter, permease
C380_15425	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C380_15430	ENOG4105BZU	Histidine kinase
C380_15435	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
C380_15445	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C380_15460	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C380_15465	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
C380_15470	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
C380_15475	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
C380_15480	ENOG4105EHG	Permease protein
C380_15485	ENOG4108HUF	Transporter
C380_15490	ENOG4108YZT	Adenosylcobinamide kinase
C380_15495	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C380_15500	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C380_15515	ENOG4105HF0	Membrane
C380_15520	ENOG4105BZU	Histidine kinase
C380_15525	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C380_15535	ENOG4105D4P	Coproporphyrinogen iii oxidase
C380_15540	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
C380_15575	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
C380_15585	ENOG4105C59	p-type ATPase
C380_15595	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_15615	ENOG4105DRR	Transcriptional regulator, GntR family
C380_15620	ENOG4105EXG	Transcriptional regulator
C380_15630	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C380_15640	ENOG4105C01	Dihydroxy-acid dehydratase
C380_15650	ENOG4105W2Z	cytochrome C, class I
C380_15660	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C380_15665	ENOG4108TEB	UPF0114 protein
C380_15680	ENOG4105EB3	Histidine kinase
C380_15685	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C380_15710	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C380_15715	ENOG4108VKG	metal-dependent hydrolase
C380_15775	ENOG4108YGG	dna repair protein
C380_15795	ENOG4105FA0	parb-like partition protein
C380_15810	ENOG4105VUN	Transcriptional regulator
C380_15815	ENOG4105K89	arsenate reductase
C380_15820	ENOG4105D6J	arsenicaL-resistance protein
C380_15835	ENOG41085FC	arsR family transcriptional regulator
C380_15870	ENOG4107QJE	Chromosome Partitioning Protein
C380_15900	ENOG4105F2I	Transposase
C380_15905	ENOG4105IKQ	hydratase
C380_15910	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
C380_15920	ENOG4106Y8B	BphX-like
C380_15960	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
C380_15965	ENOG4106NZI	LysR family Transcriptional regulator
C380_16060	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C380_16065	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C380_16070	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C380_16075	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C380_16085	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C380_16095	ENOG4105EJQ	L-serine dehydratase
C380_16105	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_16110	ENOG4105FE1	phytoene synthase
C380_16115	ENOG4107S11	squalene-associated FAD-dependent desaturase
C380_16130	ENOG4105ECM	Sensor protein basS pmrB
C380_16155	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
C380_16160	ENOG4108M60	Transcriptional regulator
C380_16170	ENOG4105D7K	pfkb domain protein
C380_16180	ENOG4105CDA	abc transporter atp-binding protein
C380_16185	ENOG4105EAB	amino acid AbC transporter
C380_16190	ENOG4105E5Q	amino acid AbC transporter
C380_16195	ENOG4105E5Q	amino acid AbC transporter
C380_16200	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C380_16205	ENOG4105DAN	ATP-dependent protease
C380_16210	ENOG4108IV0	ABC, transporter
C380_16215	ENOG4105C0Z	ABC transporter
C380_16225	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_16235	ENOG4105CGU	Enoyl-CoA hydratase
C380_16280	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C380_16285	ENOG4105E5G	Alpha beta hydrolase fold
C380_16315	ENOG410816E	Phosphotransferase enzyme family
C380_16325	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
C380_16330	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C380_16340	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C380_16345	ENOG4108QDE	fad dependent oxidoreductase
C380_16375	ENOG4106BE1	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers (By similarity)
C380_16380	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C380_16390	ENOG4108IV0	ABC, transporter
C380_16395	ENOG4105C0Z	ABC transporter
C380_16410	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C380_16440	ENOG4105DHQ	Histidine kinase
C380_16445	ENOG4105VEJ	Heat shock protein
C380_16450	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C380_16455	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_16460	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
C380_16470	ENOG4105C8N	cysteinyl-tRNA synthetase
C380_16495	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
C380_16500	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
C380_16510	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C380_16515	ENOG4108YXU	transcriptional regulator AsnC family
C380_16525	ENOG4108XM1	transcriptional regulator AsnC family
C380_16535	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
C380_16540	ENOG4108YZN	class I peptide chain release factor
C380_16545	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C380_16555	ENOG4105CX6	glutaminyL-tRNA synthetase
C380_16615	ENOG4105F87	Dehydratase
C380_16625	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C380_16635	ENOG4108R99	pseudouridine synthase
C380_16645	ENOG4108K3A	Glutathione S-transferase
C380_16700	ENOG4105DR9	pseudouridine synthase
C380_16705	ENOG4105EA8	2-Nitropropane dioxygenase
C380_16710	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C380_16720	ENOG4105BZU	Histidine kinase
C380_16745	ENOG4105EQ0	Major Facilitator superfamily
C380_16755	ENOG4105BZU	Histidine kinase
C380_16760	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
C380_16775	ENOG4105D9M	gamma-glutamylcysteine synthetase
C380_16780	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
C380_16800	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C380_16805	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C380_16810	ENOG4107YIM	Involved in the transcription termination process (By similarity)
C380_16815	ENOG4105CHM	Aminotransferase
C380_16820	ENOG4107YD3	Thioesterase
C380_16825	ENOG4105E02	MotA TolQ exbB proton channel
C380_16830	ENOG4105M8F	Biopolymer transport protein exbD tolR
C380_16840	ENOG4105CSH	Transporter
C380_16845	ENOG4105E2S	oxidase) subunit II
C380_16850	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C380_16855	ENOG4105CCU	oxidase (Subunit III)
C380_16860	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
C380_16870	ENOG4105BZU	Histidine kinase
C380_16875	ENOG4108UYB	regulatoR
C380_16880	ENOG4108DQG	in Escherichia coli SbmA is involved in uptake of microcin J25
C380_16895	ENOG4107QIJ	Aconitate hydratase 2
C380_16910	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C380_16915	ENOG4105FDP	GntR family transcriptional regulator
C380_16925	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
C380_16935	ENOG4105E33	succinate dehydrogenase
C380_16940	ENOG41060IS	Flavinator of succinate dehydrogenase
C380_16945	ENOG4105BZN	citrate synthase
C380_16965	ENOG4108W6C	Dehydrogenase
C380_16985	ENOG4105DIJ	Phosphoethanolamine transferase
C380_17000	ENOG410830R	acetyltransferase
C380_17030	ENOG4105DRR	Transcriptional regulator, GntR family
C380_17075	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_17085	ENOG4105C0Z	ABC transporter
C380_17090	ENOG4108IV0	ABC, transporter
C380_17095	ENOG4105RE0	Asp Glu hydantoin racemase
C380_17110	ENOG4108UAU	isochorismatase
C380_17125	ENOG4106IQC	argininosuccinate lyase
C380_17130	ENOG4105RQF	LysR family Transcriptional regulator
C380_17135	ENOG4105F2I	Transposase
C380_17155	ENOG4107RZC	phospholipase d
C380_17160	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
C380_17170	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C380_17185	ENOG4105WH1	Two component transcriptional regulator luxr family
C380_17190	ENOG4105BZU	Histidine kinase
C380_17195	ENOG4107RGH	Aldehyde dehydrogenase
C380_17205	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C380_17225	ENOG4106855	Competence protein
C380_17275	ENOG4105CSU	acyl-Coa dehydrogenase
C380_17280	ENOG4105C10	Electron transfer flavoprotein
C380_17285	ENOG4105BZJ	Electron transfer flavoprotein
C380_17290	ENOG4105EGS	Mechanosensitive ion channel
C380_17295	ENOG4108VUG	Enoyl-CoA hydratase
C380_17300	ENOG4105DGU	Histone deacetylase
C380_17305	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C380_17315	ENOG4105F8C	transglutaminase domain-containing protein
C380_17320	ENOG4105CVE	Lytic murein transglycosylase
C380_17325	ENOG4105DA5	(ABC) transporter
C380_17330	ENOG4105E3A	(ABC) transporter
C380_17335	ENOG4105ES9	amino acid
C380_17345	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C380_17350	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C380_17355	ENOG410624X	efflux transporter, rnd family, mfp subunit
C380_17385	ENOG4105C0Z	ABC transporter
C380_17390	ENOG4108IV0	ABC, transporter
C380_17400	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C380_17415	ENOG4105I5W	Transporter
C380_17425	ENOG4105D7T	ABC transporter
C380_17430	ENOG41080XP	Cbs domain
C380_17445	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C380_17450	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_17455	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
C380_17460	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
C380_17465	ENOG4105ETE	Transcriptional regulator (LacI family
C380_17470	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C380_17480	ENOG4105D9P	serine threonine protein kinase
C380_17485	ENOG4108IFG	nitrite reductase, (NAD(P)H)
C380_17500	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
C380_17505	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C380_17510	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C380_17540	ENOG4105CNM	Receptor
C380_17545	ENOG4105CBX	hi0933 family
C380_17550	ENOG4105BZU	Histidine kinase
C380_17555	ENOG4105VCC	30S ribosomal protein S21
C380_17565	ENOG4105EJC	lysr family transcriptional regulator
C380_17570	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C380_17580	ENOG4105EVZ	LysR family transcriptional regulator
C380_17595	ENOG4105CGD	Nad-dependent epimerase dehydratase
C380_17600	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
C380_17605	ENOG4105N42	UPF0307 protein
C380_17610	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
C380_17620	ENOG4105D7W	serine acetyltransferase
C380_17630	ENOG4105ECY	inositol monophosphatase
C380_17635	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C380_17640	ENOG4105BZU	Histidine kinase
C380_17645	ENOG4105BZU	Histidine kinase
C380_17650	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C380_17675	ENOG4105BZU	Histidine kinase
C380_17680	ENOG4105BZU	Histidine kinase
C380_17685	ENOG4105BZU	Histidine kinase
C380_17695	ENOG4105BZU	Histidine kinase
C380_17705	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C380_17735	ENOG4108HRK	Histidine kinase
C380_17740	ENOG4108VAC	response regulator
C380_17745	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C380_17750	ENOG4105BZS	acriflavin resistance protein
C380_17765	ENOG410829K	Lysine exporter protein (Lyse ygga)
C380_17770	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
C380_17775	ENOG4108594	Permease of the drug metabolite transporter
C380_17780	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
C380_17785	ENOG4105C09	Bile acid
C380_17790	ENOG4105H3G	oxidoreductase
C380_17795	ENOG4107FW0	short-chain dehydrogenase reductase
C380_17800	ENOG4108FUF	Transcriptional regulator, IclR family
C380_17825	ENOG4105BZU	Histidine kinase
C380_17835	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C380_17840	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C380_17855	ENOG4105BZU	Histidine kinase
C380_17870	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
C380_17910	ENOG4108Z4X	TRANSCRIPTIONal
C380_17920	ENOG4105CS1	NAD(P)H quinone oxidoreductase
C380_17930	ENOG4105D6J	arsenicaL-resistance protein
C380_17945	ENOG41085FC	arsR family transcriptional regulator
C380_17950	ENOG4105BZU	Histidine kinase
C380_17975	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C380_17980	ENOG4108VJC	ABC transporter, periplasmic molybdate-binding protein
C380_17990	ENOG4105CDA	abc transporter atp-binding protein
C380_18010	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_18015	ENOG4105CH5	extracellular solute-binding protein, family 7
C380_18020	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C380_18030	ENOG41086K9	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C380_18045	ENOG4105KHC	sulfurtransferase
C380_18050	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
C380_18055	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
C380_18080	ENOG4108QUU	Morphogenesis Protein
C380_18085	ENOG4105QIB	mu-like prophage Flumu protein gp29
C380_18090	ENOG4105CF2	Mu-like prophage FluMu protein GP28
C380_18145	ENOG41067QW	Transcriptional regulator
C380_18220	ENOG4105DH7	May be involved in recombination (By similarity)
C380_18245	ENOG4108TVE	i protein
C380_18255	ENOG4105EFV	Major head subunit
C380_18325	ENOG4105DSF	transport protein
C380_18335	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C380_18340	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C380_18360	ENOG4105DS1	cytochrome b561
C380_18365	ENOG4108YYC	ycei family
C380_18380	ENOG4105D0M	Protease HtpX homolog
C380_18385	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C380_18390	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C380_18395	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
C380_18405	ENOG4105C6T	cysteine synthase
C380_18420	ENOG4105ETT	transcriptional Regulator, LysR family
C380_18425	ENOG4105C1G	acyl-Coa dehydrogenase
C380_18430	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C380_18435	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_18440	ENOG410908U	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C380_18455	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C380_18470	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
C380_18475	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_18480	ENOG4108RYK	Nad-dependent epimerase dehydratase
C380_18485	ENOG4105CR8	Transcriptional regulator
C380_18495	ENOG4107R88	Chemotaxis protein (CheV)
C380_18520	ENOG4105BZU	Histidine kinase
C380_18525	ENOG4108ZXC	Two component transcriptional regulator, luxr family
C380_18535	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C380_18540	ENOG4105DJ0	Poly(A) Polymerase
C380_18550	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
C380_18560	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C380_18585	ENOG4105E7U	AraC family transcriptional regulator
C380_18600	ENOG4105CSR	polyphosphate kinase 2
C380_18615	ENOG41063JG	Transcriptional regulator
C380_18620	ENOG4105CJR	Integral membrane protein (MviN
C380_18625	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
C380_18640	ENOG4105C8Y	Acetylornithine aminotransferase
C380_18645	ENOG4105DBV	ornithine carbamoyltransferase
C380_18655	ENOG4105CE1	Ferrous iron transport protein b
C380_18710	ENOG4105PI0	Ferredoxin
C380_18715	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
C380_18725	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
C380_18750	ENOG4105ED1	spovr family
C380_18755	ENOG4106AKX	UPF0229 protein
C380_18760	ENOG4105CYN	Serine protein kinase
C380_18765	ENOG4105MSY	salicylate hydroxylase
C380_18770	ENOG4105BZU	Histidine kinase
C380_18775	ENOG4105BZU	Histidine kinase
C380_18780	ENOG4107QM5	aconitate hydratase
C380_18795	ENOG4107M1U	Histone family protein nucleoid-structuring protein H-NS
C380_18800	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
C380_18805	ENOG4105C1J	atp-dependent rna helicase
C380_18810	ENOG4105CV6	ABC transporter, permease
C380_18825	ENOG4105VFU	Rna-binding protein
C380_18830	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C380_18850	ENOG4105QAX	Iron-sulfur
C380_18855	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
C380_18885	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
C380_18895	ENOG4105C5Q	Transcriptional regulator
C380_18920	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C380_18950	ENOG4108IYU	L-aspartate oxidase
C380_18955	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C380_18960	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
C380_18965	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C380_18975	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
C380_18980	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C380_18990	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C380_19010	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
C380_19015	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C380_19020	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C380_19025	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C380_19040	ENOG4105NPQ	Pfam:DUF403
C380_19085	ENOG4106H29	UPF0391 membrane protein
C380_19095	ENOG4105WH1	Two component transcriptional regulator luxr family
C380_19105	ENOG4105D06	uba thif-type nad fad binding protein
C380_19110	ENOG4105CN1	protease
C380_19115	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C380_19120	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C380_19125	ENOG4105VW4	glutaredoxin 3
C380_19130	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
C380_19135	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C380_19140	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C380_19145	ENOG4105RQF	LysR family Transcriptional regulator
C380_19150	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C380_19155	ENOG4106H78	methyltransferase
C380_19160	ENOG4105C1V	Peptidase, M16
C380_19175	ENOG4105BZU	Histidine kinase
C380_19185	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C380_19200	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C380_19225	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
C380_19235	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
C380_19245	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C380_19250	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
C380_19260	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
C380_19265	ENOG41081UC	Inherit from COG: Competence protein
C380_19270	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C380_19275	ENOG4105CC0	LysR family Transcriptional regulator
C380_19290	ENOG410829K	Lysine exporter protein (Lyse ygga)
C380_19295	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C380_19300	ENOG4105EN6	Membrane
C380_19315	ENOG4108PZW	LysR family Transcriptional regulator
C380_19330	ENOG4105CHR	reductase
C380_19335	ENOG4105CHU	acetyl-coa acetyltransferase
C380_19340	ENOG4107QNJ	CoA-transferase subunit B
C380_19350	ENOG4107HP6	Transcriptional regulator
C380_19375	ENOG4108IV0	ABC, transporter
C380_19380	ENOG4105C0Z	ABC transporter
C380_19390	ENOG4105C32	Amino acid ABC transporter (Permease)
C380_19395	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C380_19400	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C380_19420	ENOG4106RE7	Cytochrome
C380_19460	ENOG4107AQZ	Membrane
C380_19470	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C380_19475	ENOG4105DHQ	Histidine kinase
C380_19480	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C380_19485	ENOG4105C4Y	ABC transporter
C380_19490	ENOG4105C0H	protease
C380_19510	ENOG4105CTX	dehydratase
C380_19515	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_19525	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C380_19535	ENOG4105E9Z	Nad-dependent epimerase dehydratase
C380_19540	ENOG4105FDP	GntR family transcriptional regulator
C380_19545	ENOG4105C26	Dehydrogenase
C380_19555	ENOG4105CNM	Receptor
C380_19565	ENOG4105BZU	Histidine kinase
C380_19570	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
C380_19575	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C380_19615	ENOG4105CD3	dihydroorotase
C380_19620	ENOG4105CXT	aspartate transcarbamylase
C380_19625	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C380_19630	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C380_19635	ENOG4108UJU	UPF0301 protein
C380_19645	ENOG4105CZX	twitching motility protein
C380_19650	ENOG4105CBS	Chea signal transduction histidine kinase
C380_19655	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_19660	ENOG4108V3W	Chemotaxis protein, CheW
C380_19665	ENOG4105M3Z	response regulator
C380_19670	ENOG4108UNF	response regulator
C380_19675	ENOG4105VCQ	rubredoxin
C380_19685	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C380_19690	ENOG4107HP6	Transcriptional regulator
C380_19695	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
C380_19700	ENOG4105W2Z	cytochrome C, class I
C380_19705	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C380_19710	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
C380_19715	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C380_19725	ENOG4105W39	Membrane
C380_19730	ENOG4105BZU	Histidine kinase
C380_19735	ENOG4105FR1	rard protein
C380_19740	ENOG4105C3G	gtp-binding protein
C380_19745	ENOG4105QVC	MOSC domain-containing protein
C380_19750	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
C380_19755	ENOG4105T95	Thiol disulfide interChange protein
C380_19765	ENOG4105E39	Enoyl-CoA hydratase
C380_19775	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C380_19780	ENOG4107WP9	Histidine kinase
C380_19790	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C380_19795	ENOG4105DJ9	glucan biosynthesis protein
C380_19800	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
C380_19805	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C380_19810	ENOG4105CRE	cytochrome C
C380_19820	ENOG4107TUY	Histidine kinase
C380_19825	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C380_19835	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C380_19840	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C380_19860	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C380_19865	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C380_19870	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
C380_19875	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C380_19885	ENOG4105DFU	Cell wall formation (By similarity)
C380_19895	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C380_19905	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
C380_19910	ENOG4105KWI	UPF0339 protein
C380_19915	ENOG4105CNI	cell division protein FtsW
C380_19920	ENOG4105D9P	serine threonine protein kinase
C380_19925	ENOG4105IPS	esterase
C380_19945	ENOG4105E2X	shikimate dehydrogenase
C380_19950	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
C380_19970	ENOG4105KNE	Phosphatidate cytidylyltransferase
C380_19975	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C380_19990	ENOG4105DEN	Luciferase family
C380_20000	ENOG4105D7Q	type ii secretion system
C380_20025	ENOG4105BZ1	(ABC) transporter
C380_20030	ENOG4108DIG	cyanophycin synthetase
C380_20040	ENOG4108RH0	Crea protein
C380_20045	ENOG4108Z33	Thiol disulfide Interchange Protein
C380_20050	ENOG4105CHR	reductase
C380_20065	ENOG4108JUB	Transcriptional regulator
C380_20070	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_20075	ENOG4105CHU	acetyl-coa acetyltransferase
C380_20105	ENOG4108UT2	hemolysin iii
C380_20115	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_20120	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
C380_20130	ENOG4105IJJ	transcriptional regulator, crp fnr family
C380_20200	ENOG4105DZ2	Transcriptional regulator
C380_20205	ENOG4105D65	subunit l
C380_20210	ENOG4105EVH	UPF0753 protein
C380_20220	ENOG4105BZU	Histidine kinase
C380_20225	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
C380_20230	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C380_20235	ENOG4105F7P	transcriptional regulator AsnC family
C380_20240	ENOG4105BZU	Histidine kinase
C380_20245	ENOG4105BZU	Histidine kinase
C380_20250	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C380_20265	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C380_20285	ENOG4105ETT	transcriptional Regulator, LysR family
C380_20290	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C380_20295	ENOG4105DR5	peptidase
C380_20300	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
C380_20305	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C380_20310	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
C380_20325	ENOG4108UJD	30S ribosomal protein S9
C380_20330	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C380_20335	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
C380_20340	ENOG4105D6S	protein involved in catabolism of external DNA
C380_20350	ENOG4105SYT	Methylenetetrahydrofolate reductase
C380_20360	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
C380_20365	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C380_20390	ENOG4105NWF	RbsD or FucU transport
C380_20395	ENOG4105C2J	ABC transporter
C380_20400	ENOG4105CNN	ABC, transporter
C380_20405	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
C380_20420	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C380_20440	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C380_20445	ENOG4105CP9	extracellular ligand-binding receptor
C380_20450	ENOG4105CP9	extracellular ligand-binding receptor
C380_20460	ENOG4105CSH	Transporter
C380_20485	ENOG4105BZS	acriflavin resistance protein
C380_20490	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C380_20495	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C380_20500	ENOG4108M0I	Transcriptional regulator
C380_20505	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C380_20520	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
C380_20535	ENOG41060WC	Enoyl-CoA hydratase
C380_20540	ENOG4105SF0	DinB family
C380_20545	ENOG4107QX3	carboxylase
C380_20550	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_20570	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C380_20575	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C380_20595	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
C380_20600	ENOG4105K5B	UPF0225 protein
C380_20635	ENOG4105DHQ	Histidine kinase
C380_20645	ENOG4105C1G	acyl-Coa dehydrogenase
C380_20660	ENOG4105CHU	acetyl-coa acetyltransferase
C380_20665	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
C380_20670	ENOG41077A9	carbonic anhydrase
C380_20675	ENOG4105C1G	acyl-Coa dehydrogenase
C380_20685	ENOG4108Z6Z	Transcriptional regulator
C380_20695	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C380_20700	ENOG4105C5H	ABC transporter
C380_20705	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C380_20710	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
C380_20715	ENOG4105BZU	Histidine kinase
C380_20720	ENOG4108V3W	Chemotaxis protein, CheW
C380_20725	ENOG4105CBS	Chea signal transduction histidine kinase
C380_20730	ENOG4107R88	Chemotaxis protein (CheV)
C380_20745	ENOG4105WH1	Two component transcriptional regulator luxr family
C380_20750	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
C380_20755	ENOG4105VS8	Flagellar biosynthetic protein fliq
C380_20760	ENOG4105CN7	Flagellar biosynthetic protein FliP
C380_20770	ENOG4105DD5	Flagellar motor switch protein
C380_20775	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C380_20780	ENOG4107ZI8	flagellar basal body-associated protein flil
C380_20795	ENOG4108JIR	Flagellum-specific ATP synthase
C380_20805	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C380_20810	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
C380_20815	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C380_20835	ENOG4105MQ3	flagellar protein FliS
C380_20840	ENOG4105DTS	flagellar hook-associated
C380_20855	ENOG4107RD7	Flagellar Motor Protein, MotA
C380_20860	ENOG4105ER2	Ompa motb domain protein
C380_20865	ENOG4108VYJ	response regulator receiver protein
C380_20870	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
C380_20875	ENOG4105D00	flagellar biosynthetic protein flhB
C380_20880	ENOG4105D7B	Flagellar biosynthesis protein flha
C380_20885	ENOG4105FZW	flagellar biosynthesis regulator FlhF
C380_20895	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C380_20915	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
C380_20920	ENOG4108ZC9	flagellar basal-body rod protein flgc
C380_20925	ENOG4105W00	Flagellar hook capping protein
C380_20930	ENOG4105BZE	flagellar hook protein, FlgE
C380_20935	ENOG4108KPB	Flagellar basal-body rod protein FlgF
C380_20940	ENOG4105CGA	flagellar basal-body rod protein FlgG
C380_20950	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C380_20955	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
C380_20960	ENOG4105E1Q	flagellar hook-associated protein
C380_20965	ENOG4105DTJ	flagellar hook-associated protein
C380_20975	ENOG4105CHM	Aminotransferase
C380_20985	ENOG4105T38	integral membrane protein
C380_20995	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C380_21000	ENOG4108TGY	Glutathione S-transferase
C380_21005	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C380_21010	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C380_21025	ENOG4107RCH	Diaminopropionate ammonia-lyase
C380_21045	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_21050	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C380_21055	ENOG4105C2J	ABC transporter
C380_21060	ENOG4105CNN	ABC, transporter
C380_21065	ENOG4105ETE	Transcriptional regulator (LacI family
C380_21070	ENOG4108RVA	ribokinase
C380_21075	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
C380_21090	ENOG4107SC1	transglycosylase
C380_21095	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C380_21100	ENOG4108RXX	maleylacetoacetate isomerase
C380_21115	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C380_21125	ENOG4108ZJD	Protein of unknown function (DUF1109)
C380_21130	ENOG4105NCT	RNA Polymerase
C380_21140	ENOG4105E18	UPF0276 protein
C380_21160	ENOG4108K4C	ec 3.1.3.12
C380_21165	ENOG4105BZP	glycoside hydrolase 15-related
C380_21170	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
C380_21195	ENOG4105C26	Dehydrogenase
C380_21200	ENOG4108KEZ	Dehydrogenase
C380_21205	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_21215	ENOG41062YB	Trap dicarboxylate transporter, dctp subunit
C380_21240	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C380_21245	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
C380_21250	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
C380_21280	ENOG4105DZ2	Transcriptional regulator
C380_21290	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
C380_21315	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C380_21330	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C380_21335	ENOG4105C9A	Phoh family
C380_21340	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C380_21345	ENOG4105EJ9	Membrane
C380_21355	ENOG41080TK	Universal stress protein
C380_21360	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C380_21370	ENOG4105BZU	Histidine kinase
C380_21385	ENOG4107SNB	ankyrin repeat protein YahD
C380_21395	ENOG4108Z9W	Outer membrane porin
C380_21410	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C380_21420	ENOG4105CHU	acetyl-coa acetyltransferase
C380_21430	ENOG4105C1J	atp-dependent rna helicase
C380_21440	ENOG4105BZU	Histidine kinase
C380_21445	ENOG4105FYV	Amp nucleosidase
C380_21475	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
C380_21485	ENOG4105K4P	CoA-binding domain protein
C380_21495	ENOG41069M3	Transcriptional regulator
C380_21505	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
C380_21515	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
C380_21525	ENOG4105DU1	integral membrane protein, terc
C380_21530	ENOG41063Z6	transcriptional regulator, lysR family
C380_21535	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
C380_21550	ENOG4107SFI	Major Facilitator superfamily
C380_21555	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C380_21565	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C380_21570	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C380_21575	ENOG4105C25	Primosomal protein n'
C380_21580	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C380_21590	ENOG4105RK9	auxin efflux carrier
C380_21600	ENOG4105C4R	Atp-dependent dna helicase
C380_21610	ENOG4105HDD	phospholipase
C380_21625	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C380_21670	ENOG4108594	Permease of the drug metabolite transporter
C380_21675	ENOG4105EW9	transcriptional regulator AsnC family
C380_21680	ENOG4105K6H	D-cysteine desulfhydrase
C380_21690	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_21740	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C380_21775	ENOG41080T7	secreted protein
C380_21795	ENOG4105IU3	Glutathione S-transferase
C380_21815	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
C380_21820	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
C380_21825	ENOG41063Z6	transcriptional regulator, lysR family
C380_21830	ENOG4108ZT0	50S ribosomal protein l17
C380_21835	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C380_21840	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C380_21845	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C380_21850	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C380_21855	ENOG41067V7	50S ribosomal protein L36
C380_21860	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C380_21865	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C380_21870	ENOG4105VPB	50S ribosomal protein L30
C380_21875	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C380_21880	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C380_21885	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C380_21890	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C380_21895	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C380_21900	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C380_21905	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C380_21910	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C380_21915	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C380_21930	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
C380_21945	ENOG4108IJ9	(ABC) transporter
C380_21950	ENOG4105E98	transcriptional regulator DeoR family
C380_21955	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C380_21960	ENOG4105II7	pyrroline-5-carboxylate reductase
C380_21965	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
C380_21970	ENOG4105BZU	Histidine kinase
C380_21975	ENOG4105BZU	Histidine kinase
C380_21980	ENOG4107Z5C	methylesterase
C380_21985	ENOG4105BZU	Histidine kinase
C380_21990	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C380_22005	ENOG4105C5Q	Transcriptional regulator
C380_22010	ENOG4105CB5	ATP-dependent DNA helicase recG
C380_22015	ENOG4105CPI	Metal Dependent Phosphohydrolase
C380_22025	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C380_22035	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C380_22045	ENOG4108M0I	Transcriptional regulator
C380_22055	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C380_22060	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C380_22070	ENOG4107QYG	anthranilate phosphoribosyltransferase
C380_22075	ENOG410829K	Lysine exporter protein (Lyse ygga)
C380_22080	ENOG4105DDQ	anthranilate synthase
C380_22100	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_22105	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C380_22135	ENOG4105DJV	ribulose-phosphate 3-epimerase
C380_22140	ENOG4105NWN	ApaG protein
C380_22155	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
C380_22160	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
C380_22170	ENOG4105DU6	RNA polymerase
C380_22175	ENOG4105E3J	oxidoreductase
C380_22200	ENOG41081QV	Universal stress protein
C380_22205	ENOG4108ZAI	phosphatidylglycerophosphatase a
C380_22210	ENOG4107TH8	cina domain protein
C380_22215	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
C380_22230	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C380_22235	ENOG4105CBC	glutamate synthase
C380_22260	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C380_22270	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C380_22275	ENOG4108IUZ	ABC transporter
C380_22295	ENOG4105C75	arginyL-tRNA synthetase
C380_22315	ENOG4105CK2	sodium dicarboxylate symporter
C380_22340	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
C380_22345	ENOG4107QP3	malate synthase g
C380_22355	ENOG41084KP	4-oxalocrotonate tautomerase
C380_22360	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C380_22365	ENOG4105E7A	Glutamine amidotransferase
C380_22370	ENOG4105D7Z	glutathione synthase
C380_22375	ENOG4105DKK	Benzoate
C380_22380	ENOG4105DFH	Transport of potassium into the cell (By similarity)
C380_22390	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
C380_22395	ENOG4105C1A	potassium transporter peripheral membrane
C380_22400	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C380_22430	ENOG4105C8T	Leucyl-tRNA synthetase
C380_22435	ENOG4105SG9	biopolymer transport protein, ExbD
C380_22445	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C380_22450	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C380_22455	ENOG41090R7	Ferric uptake
C380_22460	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C380_22465	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
C380_22470	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
C380_22480	ENOG4105C8V	SAICAR synthetase
C380_22485	ENOG4105K63	Thioredoxin
C380_22490	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C380_22495	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C380_22500	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C380_22540	ENOG4105W3H	MtN3 and saliva related transmembrane protein
C380_22555	ENOG41072GX	Peptidase M22 Glycoprotease
C380_22570	ENOG4107QUT	magnesium and cobalt transport protein CorA
C380_22575	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C380_22580	ENOG4105CEY	Amp-dependent synthetase and ligase
C380_22585	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C380_22590	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C380_22600	ENOG4105D2N	Aldolase
C380_22605	ENOG4105ECM	Sensor protein basS pmrB
C380_22610	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C380_22620	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
C380_22625	ENOG4105CA9	Pyruvate kinase
C380_22635	ENOG4107RAQ	aminopeptidase
C380_22640	ENOG4108S0S	Nucleotidyl transferase
C380_22645	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
C380_22650	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C380_22655	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C380_22660	ENOG4105D64	Mechanosensitive ion channel
C380_22670	ENOG4105CDV	Ompa motb domain protein
C380_22675	ENOG4105CPC	Aldo Keto reductase
C380_22685	ENOG41061H0	Monooxygenase
C380_22690	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C380_22710	ENOG4105GAK	amidohydrolase 2
C380_22725	ENOG4105KHM	amidohydrolase 2
C380_22735	ENOG4105DND	Transcriptional regulator
C380_22750	ENOG4108IV0	ABC, transporter
C380_22755	ENOG4105C0Z	ABC transporter
C380_22765	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C380_22795	ENOG4108Z86	Glutamine amidotransferase
C380_22835	ENOG4105EXG	Transcriptional regulator
C380_22850	ENOG4105EUB	pirin domain protein
C380_22870	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
C380_22880	ENOG4105D29	Helix-turn-helix type 11 domain protein
C380_22895	ENOG4108IXY	short-chain dehydrogenase reductase
C380_22900	ENOG4105HEI	LysR family (Transcriptional regulator
C380_22905	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
C380_22910	ENOG4105EQ2	LysR family Transcriptional regulator
C380_22930	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C380_22935	ENOG4105E0F	Histidine kinase
C380_22940	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
C380_22945	ENOG4105C26	Dehydrogenase
C380_22955	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_22965	ENOG4108594	Permease of the drug metabolite transporter
C380_22980	ENOG4105EQ2	LysR family Transcriptional regulator
C380_22985	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
C380_22990	ENOG4105BZA	Phosphoglycerate kinase
C380_23005	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C380_23015	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C380_23025	ENOG4105C79	DNA protecting protein DprA
C380_23035	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C380_23040	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C380_23045	ENOG4105VIE	preprotein translocase, subunit YajC
C380_23055	ENOG4108YXU	transcriptional regulator AsnC family
C380_23070	ENOG4105UYK	outer membrane protein a
C380_23080	ENOG4105BZU	Histidine kinase
C380_23095	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C380_23140	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C380_23180	ENOG4107S9B	Shikimate dehydrogenase
C380_23185	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C380_23190	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C380_23195	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
C380_23200	ENOG4108W9H	Tetr family transcriptional regulator
C380_23205	ENOG4108U78	Glutathione S-transferase
C380_23210	ENOG4107QTF	adenylosuccinate lyase
C380_23215	ENOG4108VWS	Yaeq family
C380_23230	ENOG4108ZCF	integral membrane protein
C380_23240	ENOG41086DT	Membrane protein of unknown function
C380_23245	ENOG4105ERG	peptidase m48, ste24p
C380_23250	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C380_23255	ENOG4105YWY	
C380_23275	ENOG4105F8J	Adenylate Guanylate cyclase
C380_23290	ENOG4105D9P	serine threonine protein kinase
C380_23295	ENOG4108ZCF	integral membrane protein
C380_23300	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C380_23305	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C380_23310	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C380_23315	ENOG4108004	Modulates RecA activity (By similarity)
C380_23320	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C380_23330	ENOG4105ETT	transcriptional Regulator, LysR family
C380_23350	ENOG4105DHQ	Histidine kinase
C380_23380	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C380_23405	ENOG4105M2Z	protein tyrosine serine phosphatase
C380_23410	ENOG4107SHS	Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites (By similarity)
C380_23415	ENOG4108MEJ	flavin reductase domain protein
C380_23435	ENOG4106IUH	DTW domain containing protein
C380_23460	ENOG4107RDB	Major Facilitator
C380_23480	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C380_23485	ENOG4105F04	LysR family Transcriptional regulator
C380_23490	ENOG4105C7F	AcnD-accessory protein PrpF
C380_23500	ENOG4108Z9W	Outer membrane porin
C380_23505	ENOG4105DAA	L-lactate
C380_23520	ENOG41079YP	Citrate utilization protein b
C380_23550	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C380_23590	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C380_23595	ENOG4105BZU	Histidine kinase
C380_23625	ENOG4105CGA	flagellar basal-body rod protein FlgG
C380_23630	ENOG4105EVZ	LysR family transcriptional regulator
C380_23635	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C380_23645	ENOG4105C26	Dehydrogenase
C380_23650	ENOG4105C6K	Malic enzyme
C380_23670	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C380_23675	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C380_23680	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
C380_23685	ENOG4105EHM	Aminoglycoside phosphotransferase
C380_23690	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C380_23695	ENOG4105BZU	Histidine kinase
C380_23725	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
C380_23730	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
C380_23740	ENOG4105XPQ	lipid carrier protein
C380_23745	ENOG4108UT2	hemolysin iii
C380_23750	ENOG4106RZ4	Peptidase U32
C380_23755	ENOG4105CFP	Peptidase U32
C380_23765	ENOG4108MGI	Transcriptional regulator
C380_23780	ENOG4105E5G	Alpha beta hydrolase fold
C380_23795	ENOG4105C8Q	Methyl-accepting chemotaxis
C380_23800	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
C380_23810	ENOG4105DWV	Homoserine O-trans-acetylase
C380_23815	ENOG4105DWV	Homoserine O-trans-acetylase
C380_23825	ENOG4105VFU	Rna-binding protein
C380_23830	ENOG4105VFU	Rna-binding protein
C380_23835	ENOG4105EMU	Dehydrogenase
C380_23845	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
C380_23850	ENOG4105C2X	Arabinose 5-phosphate isomerase
C380_23860	ENOG4105BZU	Histidine kinase
C380_23865	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C380_23880	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C380_23895	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C380_23900	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C380_23905	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C380_23910	ENOG4105VG0	50S ribosomal protein l34