locus-tag	class	description
YS110_00005	COG0582	viral genome integration into host DNA
YS110_00010	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
YS110_00140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
YS110_00145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YS110_00165	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YS110_00180	COG1492	cobalamin metabolic process
YS110_00190	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
YS110_00200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YS110_00210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_00215	COG2900	Belongs to the SlyX family
YS110_00225	COG3530	Putative quorum-sensing-regulated virulence factor
YS110_00235	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
YS110_00240	COG1959	2 iron, 2 sulfur cluster binding
YS110_00245	COG0583	DNA-binding transcription factor activity
YS110_00260	COG0560	Phosphoserine phosphatase
YS110_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YS110_00305	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
YS110_00305	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YS110_00310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YS110_00330	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_00340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YS110_00355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YS110_00355	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
YS110_00360	COG2860	membrane
YS110_00365	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
YS110_00370	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YS110_00375	COG0431	NADPH-dependent FMN reductase
YS110_00380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YS110_00390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YS110_00395	COG1116	anion transmembrane transporter activity
YS110_00405	COG0583	DNA-binding transcription factor activity
YS110_00415	COG1045	serine acetyltransferase
YS110_00420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_00425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YS110_00440	COG0688	phosphatidylethanolamine metabolic process
YS110_00445	COG0517	IMP dehydrogenase activity
YS110_00445	COG1125	glycine betaine transport
YS110_00450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YS110_00460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YS110_00475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_00480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YS110_00495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YS110_00505	COG2917	probably involved in intracellular septation
YS110_00510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YS110_00515	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
YS110_00520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_00530	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_00540	COG0559	Belongs to the binding-protein-dependent transport system permease family
YS110_00550	COG0411	ABC transporter
YS110_00560	COG1024	Enoyl-CoA hydratase
YS110_00560	COG1250	3-hydroxyacyl-CoA dehydrogenase
YS110_00565	COG0183	Belongs to the thiolase family
YS110_00570	COG1305	Transglutaminase-like
YS110_00600	COG2308	Evidence 4 Homologs of previously reported genes of
YS110_00620	COG0670	Belongs to the BI1 family
YS110_00625	COG3193	protein, possibly involved in utilization of glycolate and propanediol
YS110_00630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YS110_00640	COG0322	excinuclease ABC activity
YS110_00650	COG0776	regulation of translation
YS110_00660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YS110_00685	COG4774	siderophore transport
YS110_00705	COG0583	DNA-binding transcription factor activity
YS110_00715	COG0347	Belongs to the P(II) protein family
YS110_00725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YS110_00745	COG1595	DNA-templated transcription, initiation
YS110_00750	COG0028	Belongs to the TPP enzyme family
YS110_00755	COG0440	acetolactate synthase activity
YS110_00760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YS110_00765	COG1183	phosphatidylcholine synthase activity
YS110_00770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YS110_00780	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YS110_00785	COG1320	monovalent cation:proton antiporter activity
YS110_00790	COG2212	antiporter activity
YS110_00800	COG0651	ATP synthesis coupled electron transport
YS110_00805	COG1006	Multisubunit Na H antiporter MnhC subunit
YS110_00810	COG2111	Na H antiporter
YS110_00810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YS110_00820	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YS110_00830	COG0776	regulation of translation
YS110_00840	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
YS110_00845	COG0287	Prephenate dehydrogenase
YS110_00850	COG0077	Prephenate dehydratase
YS110_00850	COG1605	Chorismate mutase
YS110_00855	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
YS110_00870	COG1024	Enoyl-CoA hydratase
YS110_00880	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
YS110_00885	COG2867	negative regulation of translational initiation
YS110_00905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YS110_00905	COG0519	Catalyzes the synthesis of GMP from XMP
YS110_00910	COG0582	viral genome integration into host DNA
YS110_00960	COG2003	Belongs to the UPF0758 family
YS110_00995	COG5489	Protein of unknown function (DUF736)
YS110_01025	COG1192	Involved in chromosome partitioning
YS110_01040	COG4959	Type IV secretory pathway protease TraF
YS110_01060	COG1902	pentaerythritol trinitrate reductase activity
YS110_01065	COG1335	isochorismatase
YS110_01085	COG0156	8-amino-7-oxononanoate synthase activity
YS110_01100	COG0367	asparagine synthase
YS110_01110	COG0583	DNA-binding transcription factor activity
YS110_01130	COG4962	Type ii secretion system protein e
YS110_01135	COG3838	Conjugal transfer protein Trbc
YS110_01145	COG3451	type IV secretory pathway VirB4
YS110_01160	COG3846	protein secretion by the type IV secretion system
YS110_01170	COG3504	Conjugal transfer protein
YS110_01235	COG1840	ABC-type Fe3 transport system, periplasmic component
YS110_01250	COG2832	Protein of unknown function (DUF454)
YS110_01255	COG0242	peptide deformylase activity
YS110_01270	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
YS110_01280	COG0047	phosphoribosylformylglycinamidine synthase activity
YS110_01280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
YS110_01285	COG2354	Protein conserved in bacteria
YS110_01290	COG3047	cAMP biosynthetic process
YS110_01305	COG0826	peptidase U32
YS110_01310	COG0590	tRNA wobble adenosine to inosine editing
YS110_01325	COG1619	proteins homologs of microcin C7 resistance protein MccF
YS110_01330	COG3621	Patatin-like phospholipase
YS110_01355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_01370	COG2022	thiamine diphosphate biosynthetic process
YS110_01385	COG0351	phosphomethylpyrimidine kinase
YS110_01390	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YS110_01390	COG2755	lipolytic protein G-D-S-L family
YS110_01395	COG0471	metal ion transport
YS110_01410	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YS110_01420	COG0492	ferredoxin-NADP+ reductase activity
YS110_01425	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
YS110_01430	COG0529	Catalyzes the synthesis of activated sulfate
YS110_01430	COG2895	sulfate adenylyltransferase (ATP) activity
YS110_01435	COG0175	sulfate reduction
YS110_01440	COG0175	sulfate reduction
YS110_01455	COG0730	response to heat
YS110_01460	COG0534	Mate efflux family protein
YS110_01475	COG0254	rRNA binding
YS110_01490	COG1902	pentaerythritol trinitrate reductase activity
YS110_01490	COG0446	pyridine nucleotide-disulphide oxidoreductase
YS110_01495	COG1024	Enoyl-CoA hydratase
YS110_01505	COG3712	iron ion homeostasis
YS110_01510	COG1595	DNA-templated transcription, initiation
YS110_01520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YS110_01540	COG1074	ATP-dependent DNA helicase activity
YS110_01565	COG4206	TonB-dependent receptor
YS110_01575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YS110_01580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_01585	COG1120	ATPase activity
YS110_01590	COG4106	trans-aconitate 2-methyltransferase activity
YS110_01600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_01605	COG1120	ATPase activity
YS110_01625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_01630	COG1120	ATPase activity
YS110_01640	COG2226	methyltransferase
YS110_01645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YS110_01680	COG0471	metal ion transport
YS110_01680	COG0490	domain, Protein
YS110_01700	COG0438	transferase activity, transferring glycosyl groups
YS110_01700	COG1216	Glycosyl transferase, family 2
YS110_01820	COG4397	Mu-like prophage major head subunit gpT
YS110_01830	COG4388	Caudovirus prohead serine protease
YS110_01850	COG2974	May be involved in recombination
YS110_01995	COG4373	Mu-like prophage FluMu protein gp28
YS110_02000	COG4383	Mu-like prophage protein gp29
YS110_02005	COG2369	cell adhesion
YS110_02055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YS110_02065	COG0835	chemotaxis
YS110_02070	COG0840	transmembrane signaling receptor activity
YS110_02120	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
YS110_02125	COG0583	DNA-binding transcription factor activity
YS110_02135	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YS110_02135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YS110_02145	COG0052	Belongs to the universal ribosomal protein uS2 family
YS110_02150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
YS110_02155	COG0528	UMP kinase activity
YS110_02160	COG0233	cytoplasmic translational termination
YS110_02165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YS110_02170	COG0575	Belongs to the CDS family
YS110_02175	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
YS110_02180	COG0750	zinc metalloprotease
YS110_02195	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YS110_02200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YS110_02205	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YS110_02210	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YS110_02215	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
YS110_02220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YS110_02225	COG0505	Belongs to the CarA family
YS110_02230	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YS110_02235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YS110_02255	COG1534	Rna-binding protein
YS110_02260	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
YS110_02265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YS110_02270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YS110_02275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YS110_02290	COG0567	Dehydrogenase, E1 component
YS110_02295	COG0508	dehydrogenase complex catalyzes the overall conversion of
YS110_02300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YS110_02305	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YS110_02315	COG0631	protein serine/threonine phosphatase activity
YS110_02320	COG1199	ATP-dependent helicase activity
YS110_02325	COG1595	DNA-templated transcription, initiation
YS110_02330	COG3712	iron ion homeostasis
YS110_02345	COG1487	ribonuclease activity
YS110_02350	COG4118	positive regulation of growth
YS110_02370	COG1487	ribonuclease activity
YS110_02380	COG1283	sodium-dependent phosphate transmembrane transporter activity
YS110_02385	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
YS110_02410	COG0433	COG0433 Predicted ATPase
YS110_02415	COG0217	transcriptional regulatory protein
YS110_02420	COG0151	Belongs to the GarS family
YS110_02425	COG0408	coproporphyrinogen oxidase activity
YS110_02430	COG0799	negative regulation of ribosome biogenesis
YS110_02435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
YS110_02440	COG0424	maF-like protein
YS110_02455	COG0714	Associated with various cellular activities
YS110_02475	COG1845	cytochrome c oxidase, subunit III
YS110_02480	COG2010	Cytochrome c
YS110_02485	COG0535	radical SAM domain protein
YS110_02505	COG3391	amine dehydrogenase activity
YS110_02510	COG2010	Cytochrome c
YS110_02520	COG1648	precorrin-2 dehydrogenase activity
YS110_02520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YS110_02525	COG1530	ribonuclease E activity
YS110_02555	COG0697	spore germination
YS110_02565	COG2890	protein-(glutamine-N5) methyltransferase activity
YS110_02580	COG0791	NLP P60 protein
YS110_02590	COG0205	6-phosphofructokinase activity
YS110_02595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YS110_02615	COG2169	Transcriptional regulator
YS110_02645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YS110_02665	COG0589	response to stress
YS110_02675	COG0183	Belongs to the thiolase family
YS110_02685	COG0564	pseudouridine synthase activity
YS110_02700	COG0436	Aminotransferase
YS110_02705	COG0583	DNA-binding transcription factor activity
YS110_02725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
YS110_02740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YS110_02750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YS110_02755	COG0252	asparaginase activity
YS110_02780	COG3712	iron ion homeostasis
YS110_02785	COG1595	DNA-templated transcription, initiation
YS110_02790	COG0563	adenylate kinase activity
YS110_02795	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
YS110_02800	COG2835	tetraacyldisaccharide 4'-kinase activity
YS110_02805	COG1663	tetraacyldisaccharide 4'-kinase activity
YS110_02810	COG0848	biopolymer transport protein
YS110_02815	COG0811	peptide transport
YS110_02820	COG1570	exodeoxyribonuclease VII activity
YS110_02825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YS110_02865	COG3712	iron ion homeostasis
YS110_02880	COG0133	tryptophan synthase activity
YS110_02900	COG1960	acyl-CoA dehydrogenase activity
YS110_02930	COG1113	amino acid transport
YS110_02940	COG1196	nuclear chromosome segregation
YS110_02955	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YS110_03000	COG3243	poly(R)-hydroxyalkanoic acid synthase
YS110_03005	COG0183	Belongs to the thiolase family
YS110_03010	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_03020	COG4804	nuclease activity
YS110_03025	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YS110_03035	COG0431	NADPH-dependent FMN reductase
YS110_03040	COG1393	Belongs to the ArsC family
YS110_03045	COG0798	PFAM Bile acid sodium symporter
YS110_03055	COG0640	Transcriptional regulator
YS110_03070	COG1475	DNA binding
YS110_03080	COG5489	Protein of unknown function (DUF736)
YS110_03085	COG1396	sequence-specific DNA binding
YS110_03125	COG4959	Type IV secretory pathway protease TraF
YS110_03145	COG0642	Histidine kinase
YS110_03155	COG3038	cytochrome b561
YS110_03185	COG2194	sulfuric ester hydrolase activity
YS110_03190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YS110_03195	COG0583	DNA-binding transcription factor activity
YS110_03215	COG4962	Type ii secretion system protein e
YS110_03220	COG3838	Conjugal transfer protein Trbc
YS110_03230	COG3451	type IV secretory pathway VirB4
YS110_03245	COG3846	protein secretion by the type IV secretion system
YS110_03270	COG0488	(ABC) transporter
YS110_03275	COG2890	protein-(glutamine-N5) methyltransferase activity
YS110_03280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YS110_03290	COG2171	N-acyltransferase activity
YS110_03295	COG0436	Aminotransferase
YS110_03300	COG0840	transmembrane signaling receptor activity
YS110_03305	COG2878	Part of a membrane complex involved in electron transport
YS110_03320	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YS110_03325	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YS110_03330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YS110_03335	COG2011	ABC-type metal ion transport system permease component
YS110_03340	COG1464	Belongs to the NlpA lipoprotein family
YS110_03360	COG3038	cytochrome b561
YS110_03370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YS110_03400	COG0259	pyridoxamine-phosphate oxidase activity
YS110_03415	COG1741	Belongs to the pirin family
YS110_03420	COG2353	YceI-like domain
YS110_03430	COG3038	cytochrome b561
YS110_03440	COG0346	lactoylglutathione lyase activity
YS110_03450	COG0243	molybdopterin cofactor binding
YS110_03470	COG1960	acyl-CoA dehydrogenase activity
YS110_03475	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_03485	COG4689	acetoacetate decarboxylase
YS110_03515	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_03520	COG3781	membrane
YS110_03530	COG0640	Transcriptional regulator
YS110_03555	COG0446	pyridine nucleotide-disulphide oxidoreductase
YS110_03570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YS110_03590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
YS110_03605	COG4770	biotin carboxylase activity
YS110_03615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YS110_03620	COG1703	isobutyryl-CoA mutase activity
YS110_03630	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YS110_03630	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YS110_03635	COG1802	Transcriptional regulator
YS110_03645	COG1022	Amp-dependent synthetase and ligase
YS110_03660	COG0488	(ABC) transporter
YS110_03665	COG0513	Belongs to the DEAD box helicase family
YS110_03675	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_03680	COG1643	Atp-dependent helicase
YS110_03690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YS110_03690	COG2755	lipolytic protein G-D-S-L family
YS110_03695	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YS110_03695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YS110_03715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YS110_03720	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
YS110_03725	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YS110_03730	COG4208	sulfate ABC transporter
YS110_03735	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YS110_03740	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YS110_03755	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
YS110_03765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YS110_03770	COG0508	dehydrogenase complex catalyzes the overall conversion of
YS110_03775	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YS110_03785	COG4566	intracellular signal transduction
YS110_03790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
YS110_03805	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YS110_03810	COG0167	dihydroorotate dehydrogenase activity
YS110_03855	COG0443	Heat shock 70 kDa protein
YS110_03870	COG0822	iron-sulfur transferase activity
YS110_03875	COG1104	cysteine desulfurase activity
YS110_03880	COG1959	2 iron, 2 sulfur cluster binding
YS110_03885	COG0556	nucleotide-excision repair
YS110_03895	COG1024	Enoyl-CoA hydratase
YS110_03940	COG3384	dioxygenase
YS110_03945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YS110_03950	COG1278	Cold shock
YS110_03990	COG1739	Uncharacterized protein family UPF0029
YS110_04000	COG0501	Belongs to the peptidase M48B family
YS110_04020	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YS110_04025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YS110_04045	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
YS110_04055	COG4181	ATPase activity
YS110_04075	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
YS110_04105	COG1741	Belongs to the pirin family
YS110_04120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YS110_04125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YS110_04130	COG3706	GGDEF domain
YS110_04135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YS110_04140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_04145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YS110_04150	COG3842	ATPase activity
YS110_04160	COG1176	ABC-type spermidine putrescine transport system, permease component I
YS110_04165	COG1177	transmembrane transport
YS110_04180	COG3971	2-oxopent-4-enoate hydratase activity
YS110_04200	COG2267	carboxylic ester hydrolase activity
YS110_04220	COG0842	Transport permease protein
YS110_04225	COG1129	ABC transporter
YS110_04225	COG0842	Transport permease protein
YS110_04230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_04250	COG0583	DNA-binding transcription factor activity
YS110_04255	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
YS110_04260	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YS110_04270	COG2828	Protein conserved in bacteria
YS110_04290	COG3800	Transcriptional regulator
YS110_04290	COG1396	sequence-specific DNA binding
YS110_04325	COG4372	Transposase
YS110_04360	COG4282	regulation of fungal-type cell wall biogenesis
YS110_04400	COG0564	pseudouridine synthase activity
YS110_04405	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YS110_04410	COG2925	Exonuclease
YS110_04430	COG4774	siderophore transport
YS110_04435	COG2951	lytic endotransglycosylase activity
YS110_04460	COG0542	response to heat
YS110_04465	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
YS110_04520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YS110_04530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
YS110_04545	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
YS110_04550	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
YS110_04555	COG1414	Transcriptional regulator
YS110_04575	COG2011	ABC-type metal ion transport system permease component
YS110_04580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YS110_04585	COG1464	Belongs to the NlpA lipoprotein family
YS110_04590	COG1464	Belongs to the NlpA lipoprotein family
YS110_04600	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
YS110_04605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
YS110_04615	COG1722	exodeoxyribonuclease VII activity
YS110_04660	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
YS110_04665	COG0181	hydroxymethylbilane synthase activity
YS110_04675	COG2959	enzyme of heme biosynthesis
YS110_04685	COG0114	fumarate hydratase activity
YS110_04690	COG0753	catalase activity
YS110_04710	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_04720	COG3033	Beta-eliminating lyase
YS110_04730	COG4120	Belongs to the binding-protein-dependent transport system permease family
YS110_04735	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
YS110_04740	COG0833	amino acid
YS110_04755	COG1487	ribonuclease activity
YS110_04765	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_04775	COG0583	DNA-binding transcription factor activity
YS110_04780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YS110_04785	COG0509	glycine decarboxylation via glycine cleavage system
YS110_04790	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YS110_04790	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YS110_04835	COG0545	Peptidyl-prolyl cis-trans isomerase
YS110_04855	COG0587	DNA-directed DNA polymerase activity
YS110_04975	COG0776	regulation of translation
YS110_04985	COG1204	response to ionizing radiation
YS110_04995	COG1403	HNH endonuclease
YS110_05010	COG2948	multi-organism process
YS110_05025	COG3846	protein secretion by the type IV secretion system
YS110_05040	COG3451	type IV secretory pathway VirB4
YS110_05055	COG4962	Type ii secretion system protein e
YS110_05070	COG0583	DNA-binding transcription factor activity
YS110_05080	COG0523	cobalamin synthesis protein
YS110_05100	COG0145	ligase activity
YS110_05105	COG4647	ligase activity
YS110_05110	COG0145	ligase activity
YS110_05120	COG1063	alcohol dehydrogenase
YS110_05145	COG1192	Involved in chromosome partitioning
YS110_05180	COG5489	Protein of unknown function (DUF736)
YS110_05190	COG1475	DNA binding
YS110_05225	COG1431	PFAM Stem cell self-renewal protein Piwi
YS110_05235	COG0514	ATP-dependent DNA helicase (RecQ)
YS110_05240	COG0582	viral genome integration into host DNA
YS110_05255	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YS110_05265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YS110_05280	COG0823	Involved in the tonB-independent uptake of proteins
YS110_05285	COG1132	(ABC) transporter
YS110_05295	COG0084	hydrolase, TatD family'
YS110_05310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YS110_05315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YS110_05350	COG0657	acetylesterase activity
YS110_05365	COG1639	'signal transduction protein
YS110_05370	COG2183	response to ionizing radiation
YS110_05400	COG2130	NADP-dependent
YS110_05415	COG1960	acyl-CoA dehydrogenase activity
YS110_05420	COG0697	spore germination
YS110_05425	COG0446	pyridine nucleotide-disulphide oxidoreductase
YS110_05425	COG1902	pentaerythritol trinitrate reductase activity
YS110_05470	COG0308	aminopeptidase N
YS110_05475	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YS110_05485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YS110_05490	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YS110_05495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
YS110_05500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
YS110_05510	COG1388	LysM domain
YS110_05510	COG0741	lytic transglycosylase activity
YS110_05515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YS110_05520	COG2226	methyltransferase
YS110_05525	COG0328	RNA-DNA hybrid ribonuclease activity
YS110_05530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YS110_05535	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YS110_05550	COG2850	peptidyl-arginine hydroxylation
YS110_05555	COG1047	Peptidyl-prolyl cis-trans
YS110_05575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YS110_05580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YS110_05605	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
YS110_05620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YS110_05630	COG0557	exoribonuclease II activity
YS110_05655	COG0741	lytic transglycosylase activity
YS110_05660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YS110_05665	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YS110_05675	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YS110_05690	COG2267	carboxylic ester hydrolase activity
YS110_05695	COG1295	ribonuclease BN
YS110_05705	COG0277	FAD linked oxidase domain protein
YS110_05735	COG1595	DNA-templated transcription, initiation
YS110_05740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
YS110_05775	COG0183	Belongs to the thiolase family
YS110_05810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YS110_05835	COG0285	dihydrofolate synthase activity
YS110_05840	COG1393	Belongs to the ArsC family
YS110_05850	COG3123	guanosine phosphorylase activity
YS110_05855	COG0137	argininosuccinate synthase activity
YS110_05860	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YS110_05870	COG1595	DNA-templated transcription, initiation
YS110_05875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YS110_05880	COG0583	DNA-binding transcription factor activity
YS110_05910	COG3712	iron ion homeostasis
YS110_05915	COG1595	DNA-templated transcription, initiation
YS110_05920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YS110_05925	COG1666	GTP binding
YS110_05940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
YS110_05960	COG3655	Transcriptional regulator
YS110_05970	COG0667	Aldo Keto reductase
YS110_06005	COG1192	Involved in chromosome partitioning
YS110_06120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YS110_06135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YS110_06135	COG0784	Response regulator, receiver
YS110_06395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YS110_06410	COG0739	heme binding
YS110_06410	COG1196	nuclear chromosome segregation
YS110_06410	COG0741	lytic transglycosylase activity
YS110_06575	COG0735	belongs to the Fur family
YS110_06595	COG0789	Transcriptional regulator
YS110_06600	COG0776	regulation of translation
YS110_06610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YS110_06615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
YS110_06620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
YS110_06625	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
YS110_06630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YS110_06645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YS110_06680	COG1253	flavin adenine dinucleotide binding
YS110_06690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YS110_06695	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
YS110_06700	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YS110_06705	COG0195	Participates in both transcription termination and antitermination
YS110_06710	COG0779	Required for maturation of 30S ribosomal subunits
YS110_06720	COG4771	TonB-dependent receptor
YS110_06730	COG0114	fumarate hydratase activity
YS110_06755	COG4172	Belongs to the ABC transporter superfamily
YS110_06760	COG4239	(ABC) transporter, permease
YS110_06785	COG4174	ABC transporter (Permease)
YS110_06800	COG4166	transmembrane transport
YS110_06805	COG0829	nickel cation binding
YS110_06840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YS110_06840	COG2205	protein histidine kinase activity
YS110_06845	COG0831	urea catabolic process
YS110_06855	COG0832	Belongs to the urease beta subunit family
YS110_06860	COG0804	urea catabolic process
YS110_06865	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
YS110_06870	COG0830	nickel cation binding
YS110_06875	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YS110_06885	COG2841	Protein conserved in bacteria
YS110_06890	COG1793	dna ligase
YS110_06915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YS110_06920	COG0746	molybdenum cofactor guanylyltransferase activity
YS110_06940	COG1522	sequence-specific DNA binding
YS110_06945	COG5006	permease, DMT superfamily
YS110_06955	COG3039	Transposase
YS110_06975	COG1380	Effector of murein hydrolase LrgA
YS110_06985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_06990	COG1271	oxidase subunit
YS110_06995	COG1294	oxidase, subunit
YS110_07010	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
YS110_07040	COG1120	ATPase activity
YS110_07045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_07050	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
YS110_07065	COG4206	TonB-dependent receptor
YS110_07080	COG0730	response to heat
YS110_07090	COG3437	response regulator, receiver
YS110_07105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_07135	COG3278	Belongs to the heme-copper respiratory oxidase family
YS110_07145	COG2217	Heavy metal translocating P-type atpase
YS110_07160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YS110_07185	COG1525	nuclease
YS110_07190	COG0564	pseudouridine synthase activity
YS110_07195	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
YS110_07205	COG5002	protein histidine kinase activity
YS110_07205	COG3850	Histidine kinase
YS110_07210	COG1289	transmembrane transporter activity
YS110_07215	COG2918	glutathione biosynthetic process
YS110_07220	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_07225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YS110_07245	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YS110_07250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YS110_07255	COG0436	Aminotransferase
YS110_07260	COG0824	Thioesterase
YS110_07280	COG0477	Major facilitator Superfamily
YS110_07290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YS110_07295	COG1845	cytochrome c oxidase, subunit III
YS110_07300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YS110_07315	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
YS110_07330	COG1595	DNA-templated transcription, initiation
YS110_07335	COG3712	iron ion homeostasis
YS110_07355	COG0826	peptidase U32
YS110_07360	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_07365	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YS110_07370	COG1960	acyl-CoA dehydrogenase activity
YS110_07375	COG1960	acyl-CoA dehydrogenase activity
YS110_07380	COG1024	Enoyl-CoA hydratase
YS110_07380	COG1250	3-hydroxyacyl-CoA dehydrogenase
YS110_07385	COG0183	Belongs to the thiolase family
YS110_07395	COG1846	Transcriptional regulator
YS110_07405	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_07410	COG1024	Enoyl-CoA hydratase
YS110_07440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YS110_07445	COG0604	alcohol dehydrogenase
YS110_07460	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_07475	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
YS110_07485	COG0655	NAD(P)H dehydrogenase (quinone) activity
YS110_07490	COG0129	dihydroxy-acid dehydratase activity
YS110_07500	COG4654	Cytochrome c, class I
YS110_07505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YS110_07510	COG4175	Glycine betaine
YS110_07515	COG4176	ABC-type proline glycine betaine transport system permease component
YS110_07520	COG2113	Glycine betaine
YS110_07530	COG1742	UPF0060 membrane protein
YS110_07550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_07560	COG3278	Belongs to the heme-copper respiratory oxidase family
YS110_07585	COG4585	Histidine kinase
YS110_07610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YS110_07620	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_07625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YS110_07630	COG0508	dehydrogenase complex catalyzes the overall conversion of
YS110_07640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
YS110_07645	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_07675	COG2186	Transcriptional regulator
YS110_07685	COG0525	valine-tRNA ligase activity
YS110_07690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YS110_07710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YS110_07745	COG0425	Belongs to the sulfur carrier protein TusA family
YS110_07770	COG0415	Belongs to the DNA photolyase family
YS110_07775	COG0625	glutathione transferase activity
YS110_07780	COG0583	DNA-binding transcription factor activity
YS110_07785	COG1960	acyl-CoA dehydrogenase activity
YS110_07790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YS110_07810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YS110_07830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YS110_07835	COG0840	transmembrane signaling receptor activity
YS110_07850	COG5001	Diguanylate cyclase
YS110_07855	COG1968	undecaprenyl-diphosphatase activity
YS110_07860	COG3275	phosphorelay sensor kinase activity
YS110_07865	COG3279	Response regulator of the LytR AlgR family
YS110_07935	COG3268	Saccharopine dehydrogenase
YS110_07965	COG0756	dUTP diphosphatase activity
YS110_07970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YS110_07975	COG0504	CTP synthase activity
YS110_07980	COG2877	3-deoxy-8-phosphooctulonate synthase activity
YS110_07985	COG0148	phosphopyruvate hydratase activity
YS110_07990	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
YS110_07995	COG4770	biotin carboxylase activity
YS110_08005	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
YS110_08010	COG0024	Methionine aminopeptidase
YS110_08055	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
YS110_08065	COG2833	Protein of unknown function (DUF455)
YS110_08070	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
YS110_08075	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
YS110_08080	COG4974	Belongs to the 'phage' integrase family
YS110_08105	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YS110_08110	COG0802	atpase or kinase
YS110_08115	COG0860	N-Acetylmuramoyl-L-alanine amidase
YS110_08120	COG0668	transmembrane transport
YS110_08130	COG0586	Pfam SNARE associated Golgi protein
YS110_08135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YS110_08140	COG0745	RESPONSE REGULATOR receiver
YS110_08170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
YS110_08175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YS110_08220	COG1007	ATP synthesis coupled electron transport
YS110_08235	COG0713	ATP synthesis coupled electron transport
YS110_08245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YS110_08250	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
YS110_08255	COG1034	ATP synthesis coupled electron transport
YS110_08270	COG0649	NAD binding
YS110_08275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YS110_08280	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YS110_08285	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YS110_08300	COG0149	triose-phosphate isomerase activity
YS110_08305	COG0604	alcohol dehydrogenase
YS110_08310	COG1185	polyribonucleotide nucleotidyltransferase activity
YS110_08315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
YS110_08320	COG0719	Fe-S assembly protein
YS110_08325	COG0396	ATPase activity
YS110_08340	COG0822	iron-sulfur transferase activity
YS110_08345	COG2151	metal-sulfur cluster biosynthetic enzyme
YS110_08365	COG4969	Belongs to the N-Me-Phe pilin family
YS110_08400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YS110_08400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YS110_08405	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
YS110_08410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YS110_08415	COG2264	protein methyltransferase activity
YS110_08430	COG2197	response regulator
YS110_08435	COG2198	Histidine kinase
YS110_08435	COG0784	Response regulator, receiver
YS110_08435	COG2205	protein histidine kinase activity
YS110_08455	COG0542	response to heat
YS110_08460	COG0314	molybdopterin synthase activity
YS110_08485	COG0303	'Molybdopterin
YS110_08490	COG1763	Mo-molybdopterin cofactor biosynthetic process
YS110_08505	COG0436	Aminotransferase
YS110_08515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YS110_08520	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
YS110_08550	COG0084	hydrolase, TatD family'
YS110_08555	COG1136	(ABC) transporter
YS110_08560	COG4591	ABC-type transport system involved in lipoprotein release permease component
YS110_08570	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YS110_08580	COG0840	transmembrane signaling receptor activity
YS110_08585	COG0840	transmembrane signaling receptor activity
YS110_08590	COG0613	PHP domain protein
YS110_08595	COG0009	L-threonylcarbamoyladenylate synthase
YS110_08600	COG1994	Peptidase M50
YS110_08605	COG0180	Tryptophanyl-tRNA synthetase
YS110_08610	COG0745	RESPONSE REGULATOR receiver
YS110_08640	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
YS110_08705	COG3148	PFAM DTW domain containing protein
YS110_08715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
YS110_08725	COG2205	protein histidine kinase activity
YS110_08725	COG5002	protein histidine kinase activity
YS110_08725	COG0784	Response regulator, receiver
YS110_08740	COG0784	Response regulator, receiver
YS110_08740	COG3437	response regulator, receiver
YS110_08765	COG0840	transmembrane signaling receptor activity
YS110_08770	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
YS110_08775	COG1047	Peptidyl-prolyl cis-trans
YS110_08780	COG2003	Belongs to the UPF0758 family
YS110_08785	COG1840	ABC-type Fe3 transport system, periplasmic component
YS110_08790	COG1178	ABC-type Fe3 transport system permease component
YS110_08795	COG3842	ATPase activity
YS110_08805	COG5002	protein histidine kinase activity
YS110_08815	COG4680	protein conserved in bacteria
YS110_08835	COG3712	iron ion homeostasis
YS110_08870	COG1193	negative regulation of DNA recombination
YS110_08875	COG1846	Transcriptional regulator
YS110_08905	COG0501	Belongs to the peptidase M48B family
YS110_08910	COG1704	LemA family
YS110_08925	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YS110_08930	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YS110_08940	COG0437	4 iron, 4 sulfur cluster binding
YS110_08945	COG2864	formate dehydrogenase
YS110_08990	COG3276	selenocysteine insertion sequence binding
YS110_09040	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_09045	COG1960	acyl-CoA dehydrogenase activity
YS110_09065	COG0489	protein tyrosine kinase activity
YS110_09085	COG5002	protein histidine kinase activity
YS110_09085	COG2205	protein histidine kinase activity
YS110_09085	COG0784	Response regulator, receiver
YS110_09090	COG2203	Gaf domain
YS110_09090	COG3706	GGDEF domain
YS110_09090	COG4251	negative regulation of phosphorylation
YS110_09090	COG5001	Diguanylate cyclase
YS110_09095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YS110_09095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YS110_09135	COG2755	lipolytic protein G-D-S-L family
YS110_09180	COG3135	benzoate transporter
YS110_09190	COG0505	Belongs to the CarA family
YS110_09195	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
YS110_09205	COG0702	epimerase
YS110_09215	COG1073	alpha beta
YS110_09230	COG0446	pyridine nucleotide-disulphide oxidoreductase
YS110_09265	COG0683	leucine binding
YS110_09295	COG4566	intracellular signal transduction
YS110_09350	COG0028	Belongs to the TPP enzyme family
YS110_09375	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YS110_09385	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
YS110_09400	COG0156	8-amino-7-oxononanoate synthase activity
YS110_09420	COG2204	response regulator
YS110_09435	COG0683	leucine binding
YS110_09475	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
YS110_09485	COG4133	protoheme IX ABC transporter activity
YS110_09495	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YS110_09500	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YS110_09545	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
YS110_09550	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
YS110_09555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YS110_09565	COG0588	phosphoglycerate mutase activity
YS110_09570	COG0793	Belongs to the peptidase S41A family
YS110_09585	COG2197	response regulator
YS110_09590	COG4585	Histidine kinase
YS110_09595	COG5487	UPF0391 membrane protein
YS110_09645	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
YS110_09650	COG0742	ribosomal rna small subunit methyltransferase
YS110_09655	COG0612	Peptidase, M16
YS110_09660	COG0612	Peptidase, M16
YS110_09700	COG1730	sister chromatid segregation
YS110_09705	COG1858	cytochrome C peroxidase
YS110_09715	COG0484	heat shock protein binding
YS110_09720	COG3171	Protein conserved in bacteria
YS110_09725	COG1120	ATPase activity
YS110_09730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_09740	COG4774	siderophore transport
YS110_09765	COG1121	(ABC) transporter
YS110_09775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YS110_09780	COG1999	signal sequence binding
YS110_09785	COG0109	protoheme IX farnesyltransferase activity
YS110_09815	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
YS110_09830	COG2226	methyltransferase
YS110_09835	COG1040	competence protein
YS110_09840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YS110_09850	COG0489	protein tyrosine kinase activity
YS110_09855	COG1280	lysine exporter protein (LysE YggA)
YS110_09860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YS110_09860	COG0475	glutathione-regulated potassium exporter activity
YS110_09880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YS110_09915	COG0724	RNA recognition motif
YS110_09920	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YS110_09930	COG0642	Histidine kinase
YS110_09955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YS110_09960	COG1393	Belongs to the ArsC family
YS110_09965	COG1178	ABC-type Fe3 transport system permease component
YS110_09970	COG3842	ATPase activity
YS110_09985	COG0540	Belongs to the ATCase OTCase family
YS110_09990	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
YS110_09995	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
YS110_10000	COG1678	Uncharacterized ACR, COG1678
YS110_10005	COG2198	Histidine kinase
YS110_10005	COG0643	Histidine kinase
YS110_10010	COG0840	transmembrane signaling receptor activity
YS110_10015	COG0835	chemotaxis
YS110_10030	COG1773	rubredoxin
YS110_10040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
YS110_10065	COG2132	Multicopper oxidase
YS110_10085	COG0138	bifunctional purine biosynthesis protein purh
YS110_10090	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YS110_10095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YS110_10100	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
YS110_10105	COG1238	metal cluster binding
YS110_10110	COG1420	regulation of RNA biosynthetic process
YS110_10115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YS110_10120	COG0497	DNA recombination
YS110_10125	COG1660	Displays ATPase and GTPase activities
YS110_10130	COG1194	a g-specific adenine glycosylase
YS110_10140	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
YS110_10155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
YS110_10165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YS110_10170	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
YS110_10175	COG0193	aminoacyl-tRNA hydrolase activity
YS110_10180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YS110_10185	COG0601	transmembrane transport
YS110_10190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YS110_10195	COG0747	negative chemotaxis
YS110_10200	COG1280	lysine exporter protein (LysE YggA)
YS110_10215	COG3258	Cytochrome c
YS110_10220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YS110_10225	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
YS110_10230	COG4521	taurine ABC transporter
YS110_10255	COG0302	gtp cyclohydrolase
YS110_10285	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
YS110_10305	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YS110_10320	COG2226	methyltransferase
YS110_10355	COG0745	RESPONSE REGULATOR receiver
YS110_10360	COG0642	Histidine kinase
YS110_10365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YS110_10375	COG1175	transmembrane transport
YS110_10380	COG0395	ABC-type sugar transport system, permease component
YS110_10385	COG3842	ATPase activity
YS110_10390	COG0584	glycerophosphoryl diester phosphodiesterase
YS110_10400	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
YS110_10405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
YS110_10410	COG2890	protein-(glutamine-N5) methyltransferase activity
YS110_10415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YS110_10420	COG1253	flavin adenine dinucleotide binding
YS110_10430	COG0442	prolyl-tRNA aminoacylation
YS110_10435	COG0494	nUDIX hydrolase
YS110_10440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
YS110_10445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YS110_10450	COG0211	Belongs to the bacterial ribosomal protein bL27 family
YS110_10455	COG0261	This protein binds to 23S rRNA in the presence of protein L20
YS110_10460	COG0142	geranyltranstransferase activity
YS110_10480	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
YS110_10485	COG0237	dephospho-CoA kinase activity
YS110_10490	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
YS110_10495	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
YS110_10500	COG0494	nUDIX hydrolase
YS110_10510	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
YS110_10515	COG0653	protein targeting
YS110_10530	COG2969	positive regulation of protein catabolic process
YS110_10535	COG0625	glutathione transferase activity
YS110_10540	COG2857	Cytochrome c1
YS110_10545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
YS110_10550	COG0723	plastoquinol--plastocyanin reductase activity
YS110_10555	COG1970	mechanosensitive ion channel activity
YS110_10560	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
YS110_10565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YS110_10570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YS110_10575	COG0805	protein transport
YS110_10580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YS110_10585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YS110_10590	COG0537	adenosine 5'-monophosphoramidase activity
YS110_10605	COG0140	phosphoribosyl-ATP diphosphatase activity
YS110_10610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YS110_10615	COG0107	imidazoleglycerol-phosphate synthase activity
YS110_10620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YS110_10650	COG0438	transferase activity, transferring glycosyl groups
YS110_10665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
YS110_10675	COG0131	Imidazoleglycerol-phosphate dehydratase
YS110_10680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YS110_10700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_10710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YS110_10715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
YS110_10720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
YS110_10730	COG0842	Transport permease protein
YS110_10735	COG1131	(ABC) transporter
YS110_10750	COG2853	Lipoprotein
YS110_10755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YS110_10760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YS110_10765	COG1127	ABC transporter
YS110_10770	COG1126	abc transporter atp-binding protein
YS110_10775	COG0765	amino acid transport
YS110_10815	COG3550	peptidyl-serine autophosphorylation
YS110_10850	COG4636	protein conserved in cyanobacteria
YS110_10860	COG0069	glutamate synthase activity
YS110_10860	COG0070	glutamate synthase
YS110_10860	COG0067	glutamate synthase
YS110_10870	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
YS110_10875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YS110_10890	COG0232	Belongs to the dGTPase family. Type 2 subfamily
YS110_10895	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
YS110_10900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YS110_10940	COG1965	Belongs to the frataxin family
YS110_10960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YS110_10965	COG1333	cytochrome c biogenesis protein
YS110_10980	COG0596	Alpha beta hydrolase
YS110_10985	COG1560	Kdo2-lipid A biosynthetic process
YS110_10995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
YS110_11010	COG1216	Glycosyl transferase, family 2
YS110_11020	COG1404	Belongs to the peptidase S8 family
YS110_11035	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YS110_11040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YS110_11065	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_11070	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_11080	COG0463	Glycosyl transferase, family 2
YS110_11090	COG0438	transferase activity, transferring glycosyl groups
YS110_11125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YS110_11130	COG0459	protein refolding
YS110_11135	COG4774	siderophore transport
YS110_11140	COG0166	Belongs to the GPI family
YS110_11150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YS110_11160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YS110_11165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
YS110_11170	COG0840	transmembrane signaling receptor activity
YS110_11175	COG1881	PFAM PEBP family protein
YS110_11180	COG4608	Belongs to the ABC transporter superfamily
YS110_11185	COG0444	Belongs to the ABC transporter superfamily
YS110_11190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YS110_11195	COG1473	amidohydrolase
YS110_11215	COG1765	OsmC-like protein
YS110_11220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YS110_11225	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
YS110_11245	COG4970	Tfp pilus assembly protein FimT
YS110_11290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YS110_11300	COG0004	ammonium transporteR
YS110_11315	COG1132	(ABC) transporter
YS110_11320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YS110_11320	COG1181	Belongs to the D-alanine--D-alanine ligase family
YS110_11325	COG1181	Belongs to the D-alanine--D-alanine ligase family
YS110_11325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YS110_11330	COG3045	CreA protein
YS110_11350	COG1566	PFAM secretion protein HlyD family protein
YS110_11355	COG2814	Major facilitator Superfamily
YS110_11390	COG0488	(ABC) transporter
YS110_11400	COG2201	protein-glutamate methylesterase activity
YS110_11405	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
YS110_11415	COG0835	chemotaxis
YS110_11420	COG0643	Histidine kinase
YS110_11420	COG2198	Histidine kinase
YS110_11425	COG2201	protein-glutamate methylesterase activity
YS110_11450	COG1987	bacterial-type flagellum assembly
YS110_11475	COG1580	Controls the rotational direction of flagella during chemotaxis
YS110_11505	COG1766	The M ring may be actively involved in energy transduction
YS110_11510	COG1677	Flagellar hook-basal body complex protein FliE
YS110_11545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
YS110_11560	COG2089	acid synthase
YS110_11565	COG0028	Belongs to the TPP enzyme family
YS110_11580	COG0546	phosphoglycolate phosphatase activity
YS110_11585	COG1216	Glycosyl transferase, family 2
YS110_11585	COG0463	Glycosyl transferase, family 2
YS110_11590	COG1216	Glycosyl transferase, family 2
YS110_11590	COG0438	transferase activity, transferring glycosyl groups
YS110_11605	COG0745	RESPONSE REGULATOR receiver
YS110_11610	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YS110_11620	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YS110_11635	COG1191	sigma factor activity
YS110_11655	COG1815	bacterial-type flagellum-dependent cell motility
YS110_11660	COG1558	bacterial-type flagellum-dependent cell motility
YS110_11665	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YS110_11675	COG4787	bacterial-type flagellum-dependent cell motility
YS110_11685	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
YS110_11690	COG0418	dihydroorotase activity
YS110_11705	COG0501	Belongs to the peptidase M48B family
YS110_11715	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
YS110_11735	COG0430	RNA-3'-phosphate cyclase activity
YS110_11740	COG1690	Belongs to the RtcB family
YS110_11760	COG4650	regulator
YS110_11775	COG4269	membrane
YS110_11785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YS110_11795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
YS110_11805	COG1126	abc transporter atp-binding protein
YS110_11810	COG0765	amino acid transport
YS110_11815	COG0765	amino acid transport
YS110_11820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YS110_11830	COG0583	DNA-binding transcription factor activity
YS110_11840	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
YS110_11840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
YS110_11845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YS110_11850	COG3706	GGDEF domain
YS110_11855	COG5265	(ABC) transporter
YS110_11875	COG1024	Enoyl-CoA hydratase
YS110_11885	COG0183	Belongs to the thiolase family
YS110_11890	COG1024	Enoyl-CoA hydratase
YS110_11890	COG1250	3-hydroxyacyl-CoA dehydrogenase
YS110_11900	COG1960	acyl-CoA dehydrogenase activity
YS110_11915	COG1132	(ABC) transporter
YS110_11920	COG1309	transcriptional regulator
YS110_11930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YS110_11945	COG0204	Acyl-transferase
YS110_11945	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_11975	COG0617	tRNA 3'-terminal CCA addition
YS110_11980	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
YS110_12005	COG1116	anion transmembrane transporter activity
YS110_12020	COG0203	ribosomal protein L17
YS110_12025	COG0202	RNA polymerase activity
YS110_12030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YS110_12035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
YS110_12040	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
YS110_12045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YS110_12050	COG0201	protein transport
YS110_12055	COG0200	Binds to the 23S rRNA
YS110_12060	COG1841	ribosomal large subunit assembly
YS110_12065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
YS110_12070	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
YS110_12075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YS110_12080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YS110_12085	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
YS110_12090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YS110_12095	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
YS110_12100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YS110_12105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YS110_12120	COG0395	ABC-type sugar transport system, permease component
YS110_12130	COG3842	ATPase activity
YS110_12135	COG3842	ATPase activity
YS110_12145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YS110_12155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YS110_12160	COG0783	Belongs to the Dps family
YS110_12170	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YS110_12195	COG2382	esterase
YS110_12200	COG4943	cyclic-guanylate-specific phosphodiesterase activity
YS110_12205	COG3706	GGDEF domain
YS110_12205	COG4251	negative regulation of phosphorylation
YS110_12205	COG5001	Diguanylate cyclase
YS110_12205	COG2203	Gaf domain
YS110_12215	COG2116	formate transmembrane transporter activity
YS110_12220	COG3707	response regulator
YS110_12230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YS110_12235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YS110_12250	COG0443	Heat shock 70 kDa protein
YS110_12260	COG0443	Heat shock 70 kDa protein
YS110_12265	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YS110_12270	COG3300	MHYT domain
YS110_12270	COG5001	Diguanylate cyclase
YS110_12275	COG0134	indole-3-glycerol-phosphate synthase activity
YS110_12285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YS110_12290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YS110_12295	COG0280	phosphate acetyltransferase
YS110_12300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
YS110_12310	COG3243	poly(R)-hydroxyalkanoic acid synthase
YS110_12315	COG0840	transmembrane signaling receptor activity
YS110_12320	COG0045	succinate-CoA ligase (ADP-forming) activity
YS110_12320	COG1042	CoA-binding domain protein
YS110_12320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YS110_12325	COG1131	(ABC) transporter
YS110_12330	COG0842	Transport permease protein
YS110_12340	COG1250	3-hydroxyacyl-CoA dehydrogenase
YS110_12345	COG1846	Transcriptional regulator
YS110_12350	COG1764	response to oxidative stress
YS110_12360	COG0515	serine threonine protein kinase
YS110_12360	COG2815	serine threonine protein kinase
YS110_12375	COG2205	protein histidine kinase activity
YS110_12430	COG1858	cytochrome C peroxidase
YS110_12505	COG2318	DinB family
YS110_12510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YS110_12515	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_12530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YS110_12535	COG4251	negative regulation of phosphorylation
YS110_12535	COG3706	GGDEF domain
YS110_12535	COG2203	Gaf domain
YS110_12535	COG5001	Diguanylate cyclase
YS110_12540	COG0747	negative chemotaxis
YS110_12545	COG3012	SEC-C Motif Domain Protein
YS110_12635	COG1960	acyl-CoA dehydrogenase activity
YS110_12640	COG1366	Belongs to the anti-sigma-factor antagonist family
YS110_12650	COG2172	sigma factor antagonist activity
YS110_12655	COG0288	reversible hydration of carbon dioxide
YS110_12685	COG2208	phosphoserine phosphatase activity
YS110_12685	COG2770	Histidine kinase
YS110_12700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YS110_12720	COG0183	Belongs to the thiolase family
YS110_12725	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
YS110_12730	COG0288	reversible hydration of carbon dioxide
YS110_12735	COG1960	acyl-CoA dehydrogenase activity
YS110_12745	COG0789	Transcriptional regulator
YS110_12770	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_12775	COG0183	Belongs to the thiolase family
YS110_12780	COG3268	Saccharopine dehydrogenase
YS110_12785	COG1960	acyl-CoA dehydrogenase activity
YS110_12820	COG0189	ligase activity
YS110_12825	COG3135	benzoate transporter
YS110_12830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YS110_12840	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YS110_12845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YS110_12850	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YS110_12860	COG4290	ribonuclease
YS110_12865	COG0280	phosphate acetyltransferase
YS110_12865	COG0281	malic enzyme
YS110_12870	COG3706	GGDEF domain
YS110_12915	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_12920	COG1275	C4-dicarboxylate transporter malic acid transport protein
YS110_12925	COG1846	Transcriptional regulator
YS110_12935	COG1012	belongs to the aldehyde dehydrogenase family
YS110_12940	COG4772	TonB-dependent receptor
YS110_12955	COG3284	Transcriptional regulator
YS110_13005	COG0446	pyridine nucleotide-disulphide oxidoreductase
YS110_13025	COG0784	Response regulator, receiver
YS110_13025	COG2198	Histidine kinase
YS110_13025	COG2205	protein histidine kinase activity
YS110_13050	COG0495	leucyl-tRNA aminoacylation
YS110_13055	COG0668	transmembrane transport
YS110_13065	COG2199	diguanylate cyclase activity
YS110_13065	COG2200	EAL domain
YS110_13065	COG2202	Pas domain
YS110_13075	COG0840	transmembrane signaling receptor activity
YS110_13090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
YS110_13095	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YS110_13100	COG0735	belongs to the Fur family
YS110_13105	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
YS110_13115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YS110_13120	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YS110_13125	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YS110_13130	COG3118	belongs to the thioredoxin family
YS110_13135	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YS110_13140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YS110_13145	COG0009	L-threonylcarbamoyladenylate synthase
YS110_13155	COG3047	cAMP biosynthetic process
YS110_13165	COG2027	D-alanyl-D-alanine carboxypeptidase
YS110_13170	COG1214	PFAM Peptidase M22, glycoprotease
YS110_13175	COG0456	acetyltransferase
YS110_13185	COG0598	Magnesium transport protein CorA
YS110_13195	COG1132	(ABC) transporter
YS110_13205	COG1216	Glycosyl transferase, family 2
YS110_13205	COG1442	glycosyl transferase family 8
YS110_13210	COG1216	Glycosyl transferase, family 2
YS110_13215	COG1215	transferase activity, transferring glycosyl groups
YS110_13265	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_13280	COG0469	pyruvate kinase activity
YS110_13285	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
YS110_13290	COG1690	Belongs to the RtcB family
YS110_13295	COG0006	proline dipeptidase activity
YS110_13300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
YS110_13305	COG4566	intracellular signal transduction
YS110_13335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_13345	COG0745	RESPONSE REGULATOR receiver
YS110_13350	COG2205	protein histidine kinase activity
YS110_13355	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
YS110_13360	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
YS110_13365	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
YS110_13375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YS110_13380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YS110_13390	COG1047	Peptidyl-prolyl cis-trans
YS110_13400	COG4774	siderophore transport
YS110_13405	COG3712	iron ion homeostasis
YS110_13420	COG0840	transmembrane signaling receptor activity
YS110_13430	COG0625	glutathione transferase activity
YS110_13435	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_13450	COG0840	transmembrane signaling receptor activity
YS110_13460	COG2365	Tyrosine phosphatase family
YS110_13470	COG1881	PFAM PEBP family protein
YS110_13510	COG0642	Histidine kinase
YS110_13525	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YS110_13530	COG2137	regulation of response to DNA damage stimulus
YS110_13545	COG0045	succinate-CoA ligase (ADP-forming) activity
YS110_13550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YS110_13555	COG0631	protein serine/threonine phosphatase activity
YS110_13560	COG1716	ATPase activity
YS110_13585	COG1216	Glycosyl transferase, family 2
YS110_13600	COG0438	transferase activity, transferring glycosyl groups
YS110_13610	COG0297	glycogen (starch) synthase activity
YS110_13630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YS110_13630	COG2755	lipolytic protein G-D-S-L family
YS110_13645	COG0315	cyclic pyranopterin monophosphate synthase activity
YS110_13655	COG1950	PFAM Membrane protein of
YS110_13665	COG0861	Integral membrane protein TerC family
YS110_13670	COG0861	Integral membrane protein TerC family
YS110_13690	COG0625	glutathione transferase activity
YS110_13720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
YS110_13740	COG4566	intracellular signal transduction
YS110_13765	COG1522	sequence-specific DNA binding
YS110_13775	COG1862	Preprotein translocase
YS110_13780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YS110_13785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YS110_13795	COG0758	DNA mediated transformation
YS110_13800	COG1652	LysM domain
YS110_13805	COG0242	peptide deformylase activity
YS110_13810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YS110_13825	COG0126	phosphoglycerate kinase activity
YS110_13840	COG0284	orotidine-5'-phosphate decarboxylase activity
YS110_13850	COG0840	transmembrane signaling receptor activity
YS110_13865	COG0456	acetyltransferase
YS110_13890	COG2814	Major facilitator Superfamily
YS110_13895	COG0629	single-stranded DNA binding
YS110_13910	COG0482	sulfurtransferase activity
YS110_13935	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YS110_13950	COG0642	Histidine kinase
YS110_13985	COG0277	FAD linked oxidase domain protein
YS110_13995	COG2096	Adenosyltransferase
YS110_14000	COG2050	protein possibly involved in aromatic compounds catabolism
YS110_14015	COG2233	PERMEase
YS110_14045	COG0501	Belongs to the peptidase M48B family
YS110_14055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YS110_14060	COG1183	phosphatidylcholine synthase activity
YS110_14065	COG4774	siderophore transport
YS110_14085	COG0850	regulation of cytokinetic process
YS110_14095	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YS110_14110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YS110_14140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_14145	COG1129	ABC transporter
YS110_14145	COG0842	Transport permease protein
YS110_14150	COG0842	Transport permease protein
YS110_14155	COG3586	endonuclease activity
YS110_14170	COG1254	Belongs to the acylphosphatase family
YS110_14195	COG0745	RESPONSE REGULATOR receiver
YS110_14205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YS110_14215	COG0840	transmembrane signaling receptor activity
YS110_14225	COG1199	ATP-dependent helicase activity
YS110_14230	COG0840	transmembrane signaling receptor activity
YS110_14235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YS110_14240	COG2824	Alkylphosphonate utilization operon protein PhnA
YS110_14250	COG2258	MOSC domain
YS110_14255	COG2189	Belongs to the N(4) N(6)-methyltransferase family
YS110_14270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YS110_14275	COG0791	NLP P60 protein
YS110_14280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YS110_14295	COG2974	May be involved in recombination
YS110_14300	COG0700	Nucleoside recognition
YS110_14310	COG1960	acyl-CoA dehydrogenase activity
YS110_14315	COG0183	Belongs to the thiolase family
YS110_14320	COG1024	Enoyl-CoA hydratase
YS110_14375	COG0789	Transcriptional regulator
YS110_14385	COG2217	Heavy metal translocating P-type atpase
YS110_14390	COG0840	transmembrane signaling receptor activity
YS110_14410	COG0745	RESPONSE REGULATOR receiver
YS110_14420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YS110_14430	COG1902	pentaerythritol trinitrate reductase activity
YS110_14435	COG0625	glutathione transferase activity
YS110_14460	COG0445	tRNA wobble uridine modification
YS110_14465	COG0357	Ribosomal RNA small subunit methyltransferase G
YS110_14475	COG1192	Involved in chromosome partitioning
YS110_14550	COG1309	transcriptional regulator
YS110_14555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_14565	COG0577	efflux transmembrane transporter activity
YS110_14565	COG1136	(ABC) transporter
YS110_14595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YS110_14600	COG2267	carboxylic ester hydrolase activity
YS110_14610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
YS110_14620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YS110_14630	COG3158	transport of potassium into the cell
YS110_14640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YS110_14655	COG3154	lipid carrier protein
YS110_14660	COG0826	peptidase U32
YS110_14665	COG0826	peptidase U32
YS110_14670	COG2814	Major facilitator Superfamily
YS110_14685	COG2267	carboxylic ester hydrolase activity
YS110_14695	COG0840	transmembrane signaling receptor activity
YS110_14705	COG0840	transmembrane signaling receptor activity
YS110_14710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YS110_14715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YS110_14720	COG2119	membrane
YS110_14725	COG0724	RNA recognition motif
YS110_14730	COG0724	RNA recognition motif
YS110_14795	COG5489	Protein of unknown function (DUF736)
YS110_14825	COG1192	Involved in chromosome partitioning
YS110_14840	COG4959	Type IV secretory pathway protease TraF
YS110_14850	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
YS110_14855	COG1877	trehalose-phosphatase activity
YS110_14865	COG0745	RESPONSE REGULATOR receiver
YS110_14870	COG2205	protein histidine kinase activity
YS110_14875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YS110_14880	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
YS110_14890	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
YS110_14920	COG0583	DNA-binding transcription factor activity
YS110_14940	COG4962	Type ii secretion system protein e
YS110_14945	COG3838	Conjugal transfer protein Trbc
YS110_14955	COG3451	type IV secretory pathway VirB4
YS110_14995	COG0300	oxidoreductase activity
YS110_15005	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YS110_15010	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YS110_15010	COG0517	IMP dehydrogenase activity
YS110_15025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YS110_15060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
YS110_15070	COG0706	membrane insertase activity
YS110_15075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
YS110_15080	COG0594	ribonuclease P activity
YS110_15085	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YS110_15090	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YS110_15105	COG2249	NAD(P)H dehydrogenase (quinone) activity
YS110_15150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YS110_15160	COG0786	glutamate:sodium symporter activity
YS110_15165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_15230	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
YS110_15240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YS110_15255	COG3712	iron ion homeostasis
YS110_15260	COG1595	DNA-templated transcription, initiation
YS110_15275	COG1595	DNA-templated transcription, initiation
YS110_15280	COG4774	siderophore transport
YS110_15285	COG3712	iron ion homeostasis
YS110_15290	COG1595	DNA-templated transcription, initiation
YS110_15300	COG3712	iron ion homeostasis
YS110_15305	COG1595	DNA-templated transcription, initiation
YS110_15315	COG1960	acyl-CoA dehydrogenase activity
YS110_15325	COG3604	Transcriptional regulator
YS110_15355	COG4636	protein conserved in cyanobacteria
YS110_15380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
YS110_15420	COG0348	domain, Protein
YS110_15425	COG0723	plastoquinol--plastocyanin reductase activity
YS110_15430	COG2204	response regulator
YS110_15445	COG2205	protein histidine kinase activity
YS110_15445	COG2198	Histidine kinase
YS110_15445	COG0784	Response regulator, receiver
YS110_15485	COG0646	methionine synthase
YS110_15485	COG1410	methionine synthase
YS110_15495	COG4771	TonB-dependent receptor
YS110_15505	COG1070	Carbohydrate kinase
YS110_15510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YS110_15515	COG0277	FAD linked oxidase domain protein
YS110_15535	COG0598	Magnesium transport protein CorA
YS110_15545	COG1981	membrane
YS110_15560	COG2945	thiolester hydrolase activity
YS110_15565	COG1686	Belongs to the peptidase S11 family
YS110_15570	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YS110_15575	COG0049	tRNA binding
YS110_15580	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YS110_15585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YS110_15590	COG0051	transcription antitermination factor activity, RNA binding
YS110_15595	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YS110_15600	COG0088	Forms part of the polypeptide exit tunnel
YS110_15605	COG0089	rRNA binding
YS110_15610	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YS110_15615	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YS110_15620	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YS110_15625	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YS110_15630	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YS110_15635	COG0255	Belongs to the universal ribosomal protein uL29 family
YS110_15640	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YS110_15645	COG0678	peroxiredoxin activity
YS110_15670	COG3909	cytochrome
YS110_15675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YS110_15685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YS110_15690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YS110_15755	COG0583	DNA-binding transcription factor activity
YS110_15760	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_15765	COG5002	protein histidine kinase activity
YS110_15765	COG3850	Histidine kinase
YS110_15790	COG3239	Fatty acid desaturase
YS110_15800	COG2207	Transcriptional regulator
YS110_15810	COG0347	Belongs to the P(II) protein family
YS110_15815	COG0004	ammonium transporteR
YS110_15820	COG2203	Gaf domain
YS110_15820	COG3706	GGDEF domain
YS110_15820	COG4251	negative regulation of phosphorylation
YS110_15820	COG5001	Diguanylate cyclase
YS110_15825	COG0277	FAD linked oxidase domain protein
YS110_15835	COG0247	lactate metabolic process
YS110_15840	COG5001	Diguanylate cyclase
YS110_15840	COG3300	MHYT domain
YS110_15865	COG0386	Belongs to the glutathione peroxidase family
YS110_15875	COG0477	Major facilitator Superfamily
YS110_15880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YS110_15885	COG1858	cytochrome C peroxidase
YS110_15895	COG0672	)-iron permease
YS110_15920	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
YS110_15925	COG0765	amino acid transport
YS110_15930	COG0765	amino acid transport
YS110_15935	COG4771	TonB-dependent receptor
YS110_15945	COG4174	ABC transporter (Permease)
YS110_15950	COG4239	(ABC) transporter, permease
YS110_15955	COG4172	Belongs to the ABC transporter superfamily
YS110_15960	COG4166	transmembrane transport
YS110_15965	COG1132	(ABC) transporter
YS110_15970	COG1132	(ABC) transporter
YS110_16040	COG0477	Major facilitator Superfamily
YS110_16080	COG0745	RESPONSE REGULATOR receiver
YS110_16085	COG2211	Major facilitator Superfamily
YS110_16100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_16105	COG0577	efflux transmembrane transporter activity
YS110_16105	COG1136	(ABC) transporter
YS110_16110	COG1538	Outer membrane efflux protein
YS110_16220	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_16225	COG4569	acetaldehyde dehydrogenase (acetylating) activity
YS110_16230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YS110_16265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_16295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YS110_16300	COG1309	transcriptional regulator
YS110_16315	COG0179	Fumarylacetoacetate (FAA) hydrolase
YS110_16325	COG0604	alcohol dehydrogenase
YS110_16330	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_16335	COG0457	Tetratricopeptide repeat
YS110_16335	COG0463	Glycosyl transferase, family 2
YS110_16350	COG0708	Exodeoxyribonuclease III
YS110_16355	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
YS110_16370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YS110_16375	COG1192	Involved in chromosome partitioning
YS110_16385	COG0154	amidase activity
YS110_16390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YS110_16395	COG1077	Cell shape determining protein MreB Mrl
YS110_16410	COG0768	penicillin binding
YS110_16425	COG0004	ammonium transporteR
YS110_16440	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YS110_16445	COG1127	ABC transporter
YS110_16460	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YS110_16465	COG0321	lipoyl(octanoyl) transferase activity
YS110_16470	COG2921	Belongs to the UPF0250 family
YS110_16480	COG0356	it plays a direct role in the translocation of protons across the membrane
YS110_16490	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
YS110_16495	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
YS110_16500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
YS110_16505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
YS110_16510	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
YS110_16515	COG0355	proton-transporting ATP synthase activity, rotational mechanism
YS110_16525	COG3245	cytochrome
YS110_16535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YS110_16540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_16580	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YS110_16590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
YS110_16595	COG0081	regulation of translation
YS110_16600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YS110_16605	COG0222	ribosome binding
YS110_16610	COG0085	RNA polymerase activity
YS110_16615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YS110_16625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YS110_16625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YS110_16635	COG5000	phosphorelay sensor kinase activity
YS110_16640	COG2204	response regulator
YS110_16650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YS110_16655	COG0792	nuclease activity
YS110_16660	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
YS110_16665	COG2823	Periplasmic or secreted lipoprotein
YS110_16670	COG2084	Dehydrogenase
YS110_16680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_16690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YS110_16700	COG1136	(ABC) transporter
YS110_16700	COG0577	efflux transmembrane transporter activity
YS110_16705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_16710	COG1309	transcriptional regulator
YS110_16720	COG4770	biotin carboxylase activity
YS110_16730	COG5001	Diguanylate cyclase
YS110_16745	COG1116	anion transmembrane transporter activity
YS110_16745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YS110_16770	COG0583	DNA-binding transcription factor activity
YS110_16775	COG0277	FAD linked oxidase domain protein
YS110_16795	COG2909	trisaccharide binding
YS110_16805	COG0683	leucine binding
YS110_16820	COG0411	ABC transporter
YS110_16830	COG0277	FAD linked oxidase domain protein
YS110_16835	COG4585	Histidine kinase
YS110_16840	COG2197	response regulator
YS110_16850	COG2223	nitrite transmembrane transporter activity
YS110_16855	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
YS110_16860	COG1140	nitrate reductase beta subunit
YS110_16865	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
YS110_16870	COG2181	nitrate reductase activity
YS110_16880	COG0288	reversible hydration of carbon dioxide
YS110_16910	COG3945	hemerythrin HHE cation binding domain
YS110_16935	COG1979	alcohol dehydrogenase
YS110_16940	COG1472	Belongs to the glycosyl hydrolase 3 family
YS110_16945	COG0243	molybdopterin cofactor binding
YS110_16950	COG1473	amidohydrolase
YS110_16965	COG4774	siderophore transport
YS110_17030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_17040	COG0326	Molecular chaperone. Has ATPase activity
YS110_17065	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YS110_17075	COG1942	4-Oxalocrotonate Tautomerase
YS110_17080	COG2814	Major facilitator Superfamily
YS110_17085	COG0121	glutamine amidotransferase
YS110_17090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_17100	COG2186	Transcriptional regulator
YS110_17105	COG1304	FMN binding
YS110_17110	COG0277	FAD linked oxidase domain protein
YS110_17115	COG4191	Histidine kinase
YS110_17120	COG1301	dicarboxylic acid transport
YS110_17140	COG3712	iron ion homeostasis
YS110_17145	COG1595	DNA-templated transcription, initiation
YS110_17160	COG0018	arginyl-trna synthetase
YS110_17170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YS110_17180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YS110_17190	COG1137	ATPase activity
YS110_17195	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YS110_17205	COG0840	transmembrane signaling receptor activity
YS110_17220	COG0653	protein targeting
YS110_17230	COG0745	RESPONSE REGULATOR receiver
YS110_17240	COG0840	transmembrane signaling receptor activity
YS110_17245	COG1546	Belongs to the CinA family
YS110_17250	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YS110_17265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
YS110_17290	COG4968	Prepilin-type N-terminal cleavage methylation domain
YS110_17305	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
YS110_17320	COG2967	ApaG domain
YS110_17325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YS110_17335	COG0546	phosphoglycolate phosphatase activity
YS110_17345	COG0840	transmembrane signaling receptor activity
YS110_17350	COG0840	transmembrane signaling receptor activity
YS110_17375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YS110_17390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
YS110_17395	COG1490	D-aminoacyl-tRNA deacylase activity
YS110_17400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YS110_17410	COG0477	Major facilitator Superfamily
YS110_17425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YS110_17435	COG0038	chloride channel
YS110_17440	COG2814	Major facilitator Superfamily
YS110_17445	COG0583	DNA-binding transcription factor activity
YS110_17455	COG2423	ornithine cyclodeaminase activity
YS110_17460	COG2010	Cytochrome c
YS110_17470	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
YS110_17485	COG4774	siderophore transport
YS110_17505	COG4804	nuclease activity
YS110_17540	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
YS110_17560	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YS110_17565	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YS110_17575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
YS110_17580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YS110_17585	COG0316	Belongs to the HesB IscA family
YS110_17590	COG2814	Major facilitator Superfamily
YS110_17595	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
YS110_17600	COG0739	heme binding
YS110_17605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YS110_17610	COG2703	oxygen carrier activity
YS110_17615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
YS110_17635	COG1522	sequence-specific DNA binding
YS110_17715	COG4372	Transposase
YS110_17810	COG1196	nuclear chromosome segregation
YS110_17830	COG2814	Major facilitator Superfamily
YS110_17835	COG2814	Major facilitator Superfamily
YS110_17845	COG0583	DNA-binding transcription factor activity
YS110_17860	COG3616	Alanine racemase, N-terminal domain
YS110_17875	COG0037	tRNA processing
YS110_17905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
YS110_17925	COG0625	glutathione transferase activity
YS110_17930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YS110_17955	COG3128	pkhd-type hydroxylase
YS110_17965	COG4774	siderophore transport
YS110_17985	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_18000	COG3186	Phenylalanine-4-hydroxylase
YS110_18015	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
YS110_18020	COG1522	sequence-specific DNA binding
YS110_18035	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YS110_18040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YS110_18050	COG0752	glycyl-tRNA synthetase alpha subunit
YS110_18055	COG0751	glycine-tRNA ligase activity
YS110_18060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YS110_18085	COG1122	ATPase activity
YS110_18095	COG1268	BioY protein
YS110_18100	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_18160	COG2255	four-way junction helicase activity
YS110_18165	COG0632	four-way junction helicase activity
YS110_18170	COG1702	phosphate starvation-inducible protein PhoH
YS110_18175	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
YS110_18180	COG0730	response to heat
YS110_18190	COG1652	LysM domain
YS110_18195	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
YS110_18215	COG4221	oxidoreductase activity
YS110_18240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YS110_18245	COG1459	type II secretion system
YS110_18250	COG2165	general secretion pathway protein
YS110_18290	COG1450	Type ii and iii secretion system protein
YS110_18315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YS110_18335	COG1216	Glycosyl transferase, family 2
YS110_18360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YS110_18365	COG0343	queuine tRNA-ribosyltransferase activity
YS110_18370	COG0589	response to stress
YS110_18385	COG0210	DNA helicase
YS110_18390	COG0679	Auxin Efflux Carrier
YS110_18400	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YS110_18405	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
YS110_18415	COG3237	CsbD-like
YS110_18425	COG1832	CoA-binding protein
YS110_18440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YS110_18445	COG4232	protein-disulfide reductase activity
YS110_18485	COG3048	D-serine ammonia-lyase activity
YS110_18490	COG0384	phenazine biosynthesis protein PhzF
YS110_18495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_18500	COG0697	spore germination
YS110_18510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_18530	COG1705	Flagellar rod assembly protein muramidase FlgJ
YS110_18530	COG3951	Flagellar rod assembly protein muramidase FlgJ
YS110_18535	COG1706	bacterial-type flagellum-dependent cell motility
YS110_18545	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YS110_18555	COG0523	cobalamin synthesis protein
YS110_18570	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
YS110_18575	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
YS110_18580	COG3829	transcription factor binding
YS110_18635	COG1172	Belongs to the binding-protein-dependent transport system permease family
YS110_18675	COG2001	Belongs to the MraZ family
YS110_18680	COG0275	rRNA processing
YS110_18685	COG3116	cell division
YS110_18695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YS110_18700	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YS110_18705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YS110_18710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
YS110_18715	COG0772	Belongs to the SEDS family
YS110_18720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YS110_18725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YS110_18730	COG1181	Belongs to the D-alanine--D-alanine ligase family
YS110_18735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YS110_18745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YS110_18750	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
YS110_18760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YS110_18770	COG0840	transmembrane signaling receptor activity
YS110_18790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
YS110_18795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YS110_18800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YS110_18810	COG0557	exoribonuclease II activity
YS110_18820	COG3150	esterase
YS110_18825	COG0772	Belongs to the SEDS family
YS110_18830	COG0312	modulator of DNA gyrase
YS110_18840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YS110_18850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YS110_18860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YS110_18865	COG0511	ligase activity, forming carbon-carbon bonds
YS110_18870	COG0439	Biotin carboxylase
YS110_18875	COG2264	protein methyltransferase activity
YS110_18885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YS110_18905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YS110_18905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YS110_18930	COG4137	Cytochrome C assembly protein
YS110_18935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YS110_18940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YS110_18945	COG4804	nuclease activity
YS110_18955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YS110_18965	COG1024	Enoyl-CoA hydratase
YS110_18985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YS110_18990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YS110_18995	COG0012	GTP binding
YS110_19010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YS110_19015	COG1758	RNA polymerase activity
YS110_19020	COG0194	GDP metabolic process
YS110_19025	COG1561	YicC-like family, N-terminal region
YS110_19045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YS110_19050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YS110_19080	COG3622	Belongs to the hyi family
YS110_19090	COG2186	Transcriptional regulator
YS110_19105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YS110_19120	COG2233	PERMEase
YS110_19150	COG1120	ATPase activity
YS110_19155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_19230	COG0281	malic enzyme
YS110_19230	COG0280	phosphate acetyltransferase
YS110_19240	COG1116	anion transmembrane transporter activity
YS110_19245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YS110_19250	COG2814	Major facilitator Superfamily
YS110_19255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YS110_19260	COG0159	tryptophan synthase activity
YS110_19265	COG0133	tryptophan synthase activity
YS110_19270	COG0135	phosphoribosylanthranilate isomerase activity
YS110_19275	COG0101	tRNA pseudouridine synthase activity
YS110_19295	COG0473	3-isopropylmalate dehydrogenase activity
YS110_19300	COG0066	3-isopropylmalate dehydratase activity
YS110_19305	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YS110_19315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YS110_19320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
YS110_19325	COG0492	ferredoxin-NADP+ reductase activity
YS110_19330	COG1674	ftsk spoiiie
YS110_19335	COG1653	transport
YS110_19345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
YS110_19385	COG0604	alcohol dehydrogenase
YS110_19390	COG1309	transcriptional regulator
YS110_19400	COG1573	uracil-dna glycosylase
YS110_19485	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YS110_19515	COG1392	Phosphate transport regulator
YS110_19520	COG0306	phosphate transporter
YS110_19535	COG0228	four-way junction DNA binding
YS110_19540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
YS110_19545	COG0336	Belongs to the RNA methyltransferase TrmD family
YS110_19550	COG0335	large ribosomal subunit rRNA binding
YS110_19555	COG0494	nUDIX hydrolase
YS110_19560	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YS110_19565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YS110_19575	COG0659	secondary active sulfate transmembrane transporter activity
YS110_19580	COG1162	GTPase activity
YS110_19585	COG2154	pterin-4-alpha-carbinolamine dehydratase
YS110_19590	COG0501	Belongs to the peptidase M48B family
YS110_19595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YS110_19605	COG0513	Belongs to the DEAD box helicase family
YS110_19610	COG5001	Diguanylate cyclase
YS110_19610	COG3300	MHYT domain
YS110_19615	COG2814	Major facilitator Superfamily
YS110_19625	COG2084	Dehydrogenase
YS110_19635	COG0516	GMP reductase activity
YS110_19640	COG0210	DNA helicase
YS110_19650	COG1785	Belongs to the alkaline phosphatase family
YS110_19655	COG1785	Belongs to the alkaline phosphatase family
YS110_19670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YS110_19695	COG0412	Dienelactone hydrolase
YS110_19710	COG4771	TonB-dependent receptor
YS110_19715	COG0500	methyltransferase
YS110_19730	COG3275	phosphorelay sensor kinase activity
YS110_19735	COG0165	Argininosuccinate lyase
YS110_19740	COG2015	COG2015, Alkyl sulfatase and related hydrolases
YS110_19765	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
YS110_19770	COG0484	heat shock protein binding
YS110_19775	COG0443	Heat shock 70 kDa protein
YS110_19780	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YS110_19785	COG0360	Binds together with S18 to 16S ribosomal RNA
YS110_19795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YS110_19800	COG0359	binds to the 23S rRNA
YS110_19815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
YS110_19820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YS110_19850	COG0697	spore germination
YS110_19865	COG0583	DNA-binding transcription factor activity
YS110_19875	COG1283	sodium-dependent phosphate transmembrane transporter activity
YS110_19890	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
YS110_19895	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YS110_19900	COG0196	riboflavin kinase activity
YS110_19910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YS110_19935	COG1960	acyl-CoA dehydrogenase activity
YS110_19940	COG1960	acyl-CoA dehydrogenase activity
YS110_19945	COG3132	Protein of unknown function, DUF480
YS110_19950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YS110_19980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YS110_19980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YS110_19990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_20025	COG1160	GTP binding
YS110_20090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YS110_20105	COG2199	diguanylate cyclase activity
YS110_20110	COG2885	chlorophyll binding
YS110_20115	COG1304	FMN binding
YS110_20120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YS110_20130	COG0840	transmembrane signaling receptor activity
YS110_20135	COG0840	transmembrane signaling receptor activity
YS110_20150	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YS110_20150	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YS110_20155	COG1297	OPT oligopeptide transporter protein
YS110_20165	COG3022	response to hydroperoxide
YS110_20170	COG1530	ribonuclease E activity
YS110_20175	COG0564	pseudouridine synthase activity
YS110_20190	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YS110_20190	COG0616	signal peptide processing
YS110_20200	COG0424	maF-like protein
YS110_20205	COG1399	metal-binding, possibly nucleic acid-binding protein
YS110_20210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YS110_20215	COG0416	fatty acid biosynthetic process
YS110_20220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YS110_20225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YS110_20230	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_20235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YS110_20240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YS110_20255	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
YS110_20260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YS110_20265	COG2205	protein histidine kinase activity
YS110_20270	COG0745	RESPONSE REGULATOR receiver
YS110_20290	COG0481	GTPase activity
YS110_20295	COG0681	Belongs to the peptidase S26 family
YS110_20305	COG0571	ribonuclease III activity
YS110_20310	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
YS110_20315	COG1381	Involved in DNA repair and RecF pathway recombination
YS110_20320	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YS110_20325	COG0736	holo-[acyl-carrier-protein] synthase activity
YS110_20360	COG2132	Multicopper oxidase
YS110_20395	COG5001	Diguanylate cyclase
YS110_20395	COG4251	negative regulation of phosphorylation
YS110_20395	COG3706	GGDEF domain
YS110_20395	COG2203	Gaf domain
YS110_20400	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
YS110_20420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
YS110_20435	COG0762	integral membrane protein
YS110_20465	COG3706	GGDEF domain
YS110_20485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YS110_20495	COG3845	ABC transporter
YS110_20500	COG4603	Belongs to the binding-protein-dependent transport system permease family
YS110_20520	COG2366	antibiotic biosynthetic process
YS110_20525	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YS110_20535	COG0537	adenosine 5'-monophosphoramidase activity
YS110_20540	COG0402	S-adenosylhomocysteine deaminase activity
YS110_20545	COG0717	Belongs to the dCTP deaminase family
YS110_20550	COG2423	ornithine cyclodeaminase activity
YS110_20555	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
YS110_20560	COG2321	neutral zinc metallopeptidase
YS110_20565	COG0513	Belongs to the DEAD box helicase family
YS110_20625	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
YS110_20640	COG0348	domain, Protein
YS110_20640	COG3901	Regulator of nitric oxide reductase transcription
YS110_20645	COG4263	nitrous-oxide reductase activity
YS110_20670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YS110_20675	COG1253	flavin adenine dinucleotide binding
YS110_20680	COG2916	Histone family protein nucleoid-structuring protein H-NS
YS110_20685	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YS110_20690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YS110_20710	COG0727	PFAM Uncharacterised protein family (UPF0153)
YS110_20720	COG1918	ferrous iron import across plasma membrane
YS110_20720	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
YS110_20735	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YS110_20740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YS110_20750	COG0268	Binds directly to 16S ribosomal RNA
YS110_20755	COG0728	peptidoglycan biosynthetic process
YS110_20765	COG0589	response to stress
YS110_20785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
YS110_20790	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YS110_20800	COG0617	tRNA 3'-terminal CCA addition
YS110_20805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YS110_20810	COG0463	Glycosyl transferase, family 2
YS110_20815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YS110_20850	COG0483	inositol monophosphate 1-phosphatase activity
YS110_20865	COG1045	serine acetyltransferase
YS110_20875	COG1063	alcohol dehydrogenase
YS110_20885	COG0521	Mo-molybdopterin cofactor biosynthetic process
YS110_20890	COG3028	Belongs to the UPF0307 family
YS110_20895	COG0312	modulator of DNA gyrase
YS110_20905	COG1752	Esterase of the alpha-beta hydrolase superfamily
YS110_20915	COG0473	3-isopropylmalate dehydrogenase activity
YS110_20935	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YS110_20945	COG2081	HI0933 family
YS110_20955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YS110_20955	COG1648	precorrin-2 dehydrogenase activity
YS110_20960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YS110_20965	COG1116	anion transmembrane transporter activity
YS110_20970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YS110_20975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YS110_20980	COG0243	molybdopterin cofactor binding
YS110_20985	COG0840	transmembrane signaling receptor activity
YS110_20990	COG0517	IMP dehydrogenase activity
YS110_20990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YS110_20995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
YS110_21005	COG0683	leucine binding
YS110_21015	COG0583	DNA-binding transcription factor activity
YS110_21025	COG1136	(ABC) transporter
YS110_21055	COG1595	DNA-templated transcription, initiation
YS110_21060	COG2951	lytic endotransglycosylase activity
YS110_21075	COG0714	Associated with various cellular activities
YS110_21085	COG1024	Enoyl-CoA hydratase
YS110_21090	COG1196	nuclear chromosome segregation
YS110_21090	COG3264	Mechanosensitive ion channel
YS110_21105	COG1960	acyl-CoA dehydrogenase activity
YS110_21120	COG2223	nitrite transmembrane transporter activity
YS110_21125	COG3228	Belongs to the MtfA family
YS110_21130	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YS110_21155	COG0215	cysteine-tRNA ligase activity
YS110_21170	COG0037	tRNA processing
YS110_21190	COG2910	NAD(P)H-binding
YS110_21200	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YS110_21205	COG2204	response regulator
YS110_21245	COG1067	ATP-dependent peptidase activity
YS110_21250	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
YS110_21270	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
YS110_21275	COG1562	ergosterol biosynthetic process
YS110_21285	COG2375	cellular response to nickel ion
YS110_21285	COG1132	(ABC) transporter
YS110_21290	COG1132	(ABC) transporter
YS110_21295	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_21300	COG4605	iron ion homeostasis
YS110_21305	COG4604	ABC transporter, ATP-binding protein
YS110_21310	COG4607	ABC-type enterochelin transport system periplasmic component
YS110_21315	COG4774	siderophore transport
YS110_21320	COG2375	cellular response to nickel ion
YS110_21330	COG1760	l-serine dehydratase
YS110_21340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_21355	COG0544	peptidyl-prolyl cis-trans isomerase activity
YS110_21360	COG0740	serine-type endopeptidase activity
YS110_21365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YS110_21370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YS110_21395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YS110_21410	COG1451	nucleotide metabolic process
YS110_21415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
YS110_21445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YS110_21465	COG0400	carboxylic ester hydrolase activity
YS110_21470	COG1228	amidohydrolase
YS110_21475	COG0668	transmembrane transport
YS110_21490	COG3634	alkyl hydroperoxide reductase activity
YS110_21515	COG3654	unkown
YS110_21550	COG2204	response regulator
YS110_21555	COG4191	Histidine kinase
YS110_21560	COG2326	polyphosphate kinase activity
YS110_21570	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YS110_21575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_21580	COG4558	Periplasmic binding protein
YS110_21595	COG4206	TonB-dependent receptor
YS110_21645	COG0798	PFAM Bile acid sodium symporter
YS110_21655	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
YS110_21670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YS110_21690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YS110_21715	COG1595	DNA-templated transcription, initiation
YS110_21735	COG1477	protein flavinylation
YS110_21740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YS110_21745	COG4771	TonB-dependent receptor
YS110_21750	COG0789	Transcriptional regulator
YS110_21770	COG2818	Glycosylase
YS110_21780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YS110_21785	COG0358	DNA primase activity
YS110_21835	COG0604	alcohol dehydrogenase
YS110_21835	COG3321	synthase
YS110_21835	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_21840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YS110_21845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YS110_21855	COG0564	pseudouridine synthase activity
YS110_21860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
YS110_21865	COG1187	pseudouridine synthase activity
YS110_21870	COG0105	UTP biosynthetic process
YS110_21875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
YS110_21890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
YS110_21895	COG0124	histidyl-tRNA synthetase
YS110_21905	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YS110_21910	COG1160	GTP binding
YS110_21915	COG1923	regulation of RNA biosynthetic process
YS110_21920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YS110_21925	COG0330	HflC and HflK could
YS110_21930	COG0330	HflC and HflK could
YS110_21940	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
YS110_21945	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YS110_22010	COG0174	glutamine synthetase
YS110_22020	COG3852	Histidine kinase
YS110_22025	COG2204	response regulator
YS110_22030	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YS110_22035	COG0708	Exodeoxyribonuclease III
YS110_22060	COG0840	transmembrane signaling receptor activity
YS110_22065	COG0840	transmembrane signaling receptor activity
YS110_22085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YS110_22090	COG2194	sulfuric ester hydrolase activity
YS110_22120	COG0039	L-malate dehydrogenase activity
YS110_22125	COG2188	Transcriptional regulator
YS110_22140	COG1053	succinate dehydrogenase
YS110_22145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YS110_22150	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
YS110_22155	COG0372	Belongs to the citrate synthase family
YS110_22165	COG2197	response regulator
YS110_22180	COG3916	Acyl-homoserine-lactone synthase
YS110_22210	COG3209	COG3209 Rhs family protein
YS110_22235	COG3191	aminopeptidase activity
YS110_22265	COG0789	Transcriptional regulator
YS110_22300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YS110_22305	COG0573	inorganic phosphate transmembrane transporter activity
YS110_22310	COG0581	inorganic phosphate transmembrane transporter activity
YS110_22315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
YS110_22320	COG0704	Plays a role in the regulation of phosphate uptake
YS110_22345	COG2948	multi-organism process
YS110_22355	COG1192	Involved in chromosome partitioning
YS110_22360	COG1475	DNA binding
YS110_22475	COG1525	nuclease
YS110_22560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YS110_22615	COG4962	Type ii secretion system protein e
YS110_22620	COG3838	Conjugal transfer protein Trbc
YS110_22625	COG5268	conjugation
YS110_22630	COG3451	type IV secretory pathway VirB4
YS110_22650	COG3701	Conjugal transfer protein