locus-tag	class	description
AciM339_0003	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AciM339_0012	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AciM339_0021	ENOG4107WA4	MmpL domain-containing protein
AciM339_0023	ENOG4105CH2	amidohydrolase
AciM339_0030	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
AciM339_0039	ENOG4107QXV	Phosphate transporter
AciM339_0041	ENOG4105CXN	decarboxylase
AciM339_0045	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AciM339_0046	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AciM339_0051	ENOG4105EHU	Circadian clock protein KaiC
AciM339_0057	ENOG4105CUT	histidyl-tRNA synthetase
AciM339_0058	ENOG4105UQX	Mate efflux family protein
AciM339_0060	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AciM339_0062	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AciM339_0063	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AciM339_0064	ENOG4105C7N	Xanthine uracil vitamin C permease
AciM339_0065	ENOG4105EEI	dihydropteroate synthase
AciM339_0069	ENOG4105D64	Mechanosensitive ion channel
AciM339_0070	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AciM339_0071	ENOG4105VYW	UPF0251 protein
AciM339_0079	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AciM339_0082	ENOG4105CQ2	DNA polymerase
AciM339_0083	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AciM339_0091	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AciM339_0092	ENOG4108DGI	Phosphoribosylformylglycinamidine synthase I
AciM339_0094	ENOG4105VG1	fes assembly suf system protein
AciM339_0100	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AciM339_0101	ENOG41062IR	nudix hydrolase
AciM339_0107	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
AciM339_0111	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AciM339_0113	ENOG4105D0M	Protease HtpX homolog
AciM339_0118	ENOG4105CHM	Aminotransferase
AciM339_0120	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AciM339_0122	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AciM339_0124	ENOG4105D3R	alkyl hydroperoxide reductase
AciM339_0125	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AciM339_0127	ENOG4108YZ8	Superoxide reductase
AciM339_0128	ENOG41090A1	ferritin
AciM339_0130	ENOG4108RAC	Rubrerythrin
AciM339_0131	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AciM339_0133	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AciM339_0134	ENOG4105CNW	domain protein
AciM339_0135	ENOG4105VCQ	rubredoxin
AciM339_0137	ENOG4105VCQ	rubredoxin
AciM339_0138	ENOG4105EW9	transcriptional regulator AsnC family
AciM339_0139	ENOG4107ZMQ	sugar fermentation stimulation protein
AciM339_0141	ENOG4108Z4K	mutator MutT protein
AciM339_0142	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AciM339_0145	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AciM339_0146	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AciM339_0147	ENOG4108VZM	50s ribosomal protein L10
AciM339_0153	ENOG4105C5H	ABC transporter
AciM339_0155	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AciM339_0158	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AciM339_0159	ENOG4105C5S	asparaginyl-tRNA synthetase
AciM339_0160	ENOG4108JQ7	(ABC) transporter
AciM339_0162	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AciM339_0168	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AciM339_0172	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AciM339_0182	ENOG4108C33	Resolvase
AciM339_0205	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AciM339_0214	ENOG4108C33	Resolvase
AciM339_0237	ENOG4105CEV	competence damage-inducible protein
AciM339_0238	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AciM339_0239	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
AciM339_0245	ENOG4107U53	septum site-determining protein minD
AciM339_0247	ENOG4105CGK	Exodeoxyribonuclease III
AciM339_0249	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AciM339_0250	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AciM339_0256	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
AciM339_0260	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AciM339_0261	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AciM339_0263	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AciM339_0264	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
AciM339_0267	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AciM339_0268	ENOG4108IEG	Formate dehydrogenase Alpha subunit
AciM339_0269	ENOG4107QIZ	NADH dehydrogenase
AciM339_0270	ENOG4105GKE	subunit e
AciM339_0273	ENOG4105EM7	Selenocysteine-specific translation elongation factor
AciM339_0277	ENOG4105EHU	Circadian clock protein KaiC
AciM339_0281	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
AciM339_0283	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AciM339_0284	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AciM339_0286	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
AciM339_0287	ENOG4107ZXI	Rhomboid family
AciM339_0288	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AciM339_0290	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AciM339_0291	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AciM339_0295	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AciM339_0296	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
AciM339_0299	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AciM339_0300	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AciM339_0304	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AciM339_0307	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AciM339_0308	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
AciM339_0309	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AciM339_0316	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AciM339_0317	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AciM339_0327	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AciM339_0328	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AciM339_0330	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AciM339_0331	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AciM339_0333	ENOG4105EXW	epimerase dehydratase
AciM339_0334	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AciM339_0337	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AciM339_0340	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AciM339_0341	ENOG4107RRU	Involved in both the arginine and lysine biosynthetic pathways (By similarity)
AciM339_0344	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AciM339_0346	ENOG4105C84	Histidine ammonia-lyase
AciM339_0349	ENOG4105EHU	Circadian clock protein KaiC
AciM339_0353	ENOG4108HHA	Transketolase
AciM339_0354	ENOG4108IUS	Transketolase
AciM339_0355	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AciM339_0357	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
AciM339_0360	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AciM339_0361	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AciM339_0364	ENOG4105C4K	Nad synthetase
AciM339_0366	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AciM339_0367	ENOG4105F7P	transcriptional regulator AsnC family
AciM339_0375	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AciM339_0377	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AciM339_0378	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AciM339_0380	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AciM339_0381	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AciM339_0385	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AciM339_0390	ENOG41081FY	multiple antibiotic resistance (MarC)-related
AciM339_0398	ENOG4105CKU	formyltetrahydrofolate synthetase
AciM339_0400	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AciM339_0416	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AciM339_0425	ENOG4107R3E	Citrate transporter
AciM339_0427	ENOG4105BZA	Phosphoglycerate kinase
AciM339_0428	ENOG4105D7N	magnesium and cobalt transport protein CorA
AciM339_0429	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AciM339_0432	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AciM339_0441	ENOG4105D1Z	hydroxypyruvate reductase
AciM339_0446	ENOG4105DG4	malate L-lactate dehydrogenase
AciM339_0448	ENOG4108I5U	Uridine phosphorylase
AciM339_0456	ENOG4108Y83	glucose-6-phosphate isomerase
AciM339_0457	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AciM339_0461	ENOG4105CHM	Aminotransferase
AciM339_0468	ENOG4107QN2	dihydrolipoyl dehydrogenase
AciM339_0480	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AciM339_0487	ENOG4105C75	arginyL-tRNA synthetase
AciM339_0493	ENOG4105EHU	Circadian clock protein KaiC
AciM339_0497	ENOG4105E66	phosphoriboisomerase A
AciM339_0499	ENOG4105WPN	DNA integration recombination invertion protein
AciM339_0503	ENOG4107VEG	TrkA-N domain protein
AciM339_0508	ENOG4105C3G	gtp-binding protein
AciM339_0510	ENOG4108MDK	Dehydrogenase
AciM339_0514	ENOG4105C5I	Dehydrogenase
AciM339_0515	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
AciM339_0519	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
AciM339_0520	ENOG4105D1F	ATP-binding protein
AciM339_0523	ENOG410838F	Glycosyl transferase family 2
AciM339_0526	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AciM339_0537	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AciM339_0540	ENOG4107QX8	SPFH domain, Band 7 family protein
AciM339_0544	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
AciM339_0545	ENOG4108JVH	Protein of unknown function DUF43
AciM339_0546	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AciM339_0555	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AciM339_0556	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AciM339_0560	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AciM339_0561	ENOG4105DJV	ribulose-phosphate 3-epimerase
AciM339_0562	ENOG4108RVA	ribokinase
AciM339_0564	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AciM339_0567	ENOG4105GRF	N-glycosylase DNA lyase
AciM339_0571	ENOG4108Z4T	Peptidase M50
AciM339_0572	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AciM339_0573	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AciM339_0578	ENOG4105C5S	asparaginyl-tRNA synthetase
AciM339_0587	ENOG4108KEZ	Dehydrogenase
AciM339_0590	ENOG4108VA3	3-hexulose-6-phosphate synthase
AciM339_0591	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AciM339_0592	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AciM339_0593	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AciM339_0595	ENOG4105DC7	peptidase M24
AciM339_0603	ENOG4105C8V	SAICAR synthetase
AciM339_0614	ENOG4105CE1	Ferrous iron transport protein b
AciM339_0616	ENOG4107NFR	Fructose-1,6-bisphosphatase
AciM339_0620	ENOG4105C8N	cysteinyl-tRNA synthetase
AciM339_0621	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
AciM339_0622	ENOG4105CHM	Aminotransferase
AciM339_0623	ENOG4105CTD	carboxy-peptidase
AciM339_0631	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AciM339_0632	ENOG4105WCJ	ec 1.1.1.193
AciM339_0635	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AciM339_0637	ENOG4108JQ7	(ABC) transporter
AciM339_0639	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AciM339_0640	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AciM339_0641	ENOG4105DEF	Extracellular solute-binding protein, family 5
AciM339_0645	ENOG4105EW9	transcriptional regulator AsnC family
AciM339_0647	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AciM339_0648	ENOG4108JJB	ABC transporter
AciM339_0652	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AciM339_0655	ENOG4105SC1	monovalent cation H antiporter subunit E
AciM339_0656	ENOG410684G	monovalent cation H antiporter subunit F
AciM339_0659	ENOG4105D65	subunit l
AciM339_0660	ENOG4105MKQ	Monovalent cation H antiporter subunit C
AciM339_0661	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AciM339_0662	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AciM339_0663	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AciM339_0664	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AciM339_0665	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AciM339_0666	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AciM339_0667	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AciM339_0671	ENOG4108IXY	short-chain dehydrogenase reductase
AciM339_0678	ENOG4105CSM	endonuclease III
AciM339_0682	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AciM339_0683	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AciM339_0686	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AciM339_0692	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AciM339_0694	ENOG4105D0M	Protease HtpX homolog
AciM339_0702	ENOG4108UK2	deaminase
AciM339_0705	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AciM339_0717	ENOG4105CHU	acetyl-coa acetyltransferase
AciM339_0718	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AciM339_0719	ENOG4105C3K	feS assembly ATPase SufC
AciM339_0720	ENOG4105DIW	FeS assembly protein SUFB
AciM339_0721	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AciM339_0723	ENOG4105DSE	periplasmic solute binding protein
AciM339_0726	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AciM339_0729	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AciM339_0732	ENOG4107RWR	Sodium hydrogen exchanger
AciM339_0737	ENOG4105CD5	CoA-binding domain protein
AciM339_0741	ENOG4108IUZ	ABC transporter
AciM339_0744	ENOG4105CD5	CoA-binding domain protein
AciM339_0745	ENOG4105CD5	CoA-binding domain protein
AciM339_0755	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AciM339_0758	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
AciM339_0762	ENOG4105WGB	oxidoreductase, delta subunit
AciM339_0763	ENOG4105DDK	oxidoreductase, beta subunit
AciM339_0764	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AciM339_0767	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AciM339_0770	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AciM339_0773	ENOG4105C6X	Major Facilitator
AciM339_0774	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AciM339_0778	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
AciM339_0779	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AciM339_0782	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AciM339_0783	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AciM339_0785	ENOG4107RY6	amino acid
AciM339_0789	ENOG4107QWP	ABC-2 type transporter
AciM339_0794	ENOG4107Z36	nucleotidyl transferase
AciM339_0795	ENOG4105CAQ	asparagine synthetase
AciM339_0796	ENOG4105E4P	ATPase (AAA
AciM339_0803	ENOG4105CPK	Glycosyl transferase (Group 1
AciM339_0805	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AciM339_0806	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AciM339_0808	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AciM339_0811	ENOG4105CPF	Cell wall formation (By similarity)
AciM339_0815	ENOG4105CK5	oxidoreductase
AciM339_0816	ENOG4105J5G	Transferase hexapeptide repeat containing protein
AciM339_0818	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AciM339_0825	ENOG4108VX5	3-methyladenine DNA glycosylase
AciM339_0829	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AciM339_0830	ENOG4107XGZ	Hydrolase
AciM339_0831	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AciM339_0835	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AciM339_0839	ENOG4105DTQ	mandelate racemase muconate lactonizing
AciM339_0842	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AciM339_0845	ENOG4105EJQ	L-serine dehydratase
AciM339_0847	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AciM339_0849	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AciM339_0850	ENOG4107QRT	dEAD DEAH box helicase
AciM339_0854	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AciM339_0861	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AciM339_0862	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AciM339_0863	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AciM339_0867	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AciM339_0868	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AciM339_0869	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AciM339_0879	ENOG4105C6N	Formate acetyltransferase
AciM339_0880	ENOG4105F1A	Pyruvate formate-lyase
AciM339_0881	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AciM339_0890	ENOG4105DBV	ornithine carbamoyltransferase
AciM339_0891	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AciM339_0892	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AciM339_0894	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AciM339_0919	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AciM339_0920	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AciM339_0921	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AciM339_0923	ENOG4105DIK	(ABC) transporter
AciM339_0926	ENOG4105CY0	Metallo-Beta-Lactamase
AciM339_0928	ENOG4105BZU	Histidine kinase
AciM339_0929	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AciM339_0930	ENOG4105VG1	fes assembly suf system protein
AciM339_0931	ENOG4108VCT	Sulfite exporter TauE/SafE
AciM339_0933	ENOG4105DC7	peptidase M24
AciM339_0936	ENOG4105PGM	cation diffusion facilitator family transporter
AciM339_0939	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AciM339_0948	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AciM339_0949	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AciM339_0955	ENOG4105C0B	DNA polymerase III (alpha subunit)
AciM339_0956	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AciM339_0957	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AciM339_0958	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AciM339_0963	ENOG4108DN8	FAD dependent oxidoreductase
AciM339_0966	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
AciM339_0967	ENOG4105BZ8	glutamate synthase
AciM339_0969	ENOG4107SHJ	sulfite reductase subunit b
AciM339_0972	ENOG4105ECY	inositol monophosphatase
AciM339_0973	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AciM339_0977	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AciM339_0978	ENOG4107QK2	May be the GTPase, regulating ATP sulfurylase activity (By similarity)
AciM339_0979	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AciM339_0980	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AciM339_0987	ENOG4108J2R	molybdopterin oxidoreductase
AciM339_0988	ENOG4107R7Y	intracellular protease Pfpi family
AciM339_0989	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AciM339_0992	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AciM339_0998	ENOG4105E5Q	amino acid AbC transporter
AciM339_0999	ENOG4105CDA	abc transporter atp-binding protein
AciM339_1001	ENOG4106PMH	Extracellular solute-binding protein family 3
AciM339_1004	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
AciM339_1009	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AciM339_1011	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AciM339_1012	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AciM339_1014	ENOG4108Z0R	Transferase
AciM339_1016	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
AciM339_1020	ENOG4105BZU	Histidine kinase
AciM339_1023	ENOG4105CI0	Citrate lyase
AciM339_1024	ENOG4105CHY	citrate lyase, alpha
AciM339_1028	ENOG4108UJD	30S ribosomal protein S9
AciM339_1029	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AciM339_1030	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AciM339_1034	ENOG4105C8T	Leucyl-tRNA synthetase
AciM339_1036	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
AciM339_1037	ENOG4107QUY	Guanine deaminase
AciM339_1038	ENOG4105BZN	citrate synthase
AciM339_1039	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AciM339_1040	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AciM339_1042	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AciM339_1046	ENOG4107VIJ	nudix hydrolase
AciM339_1050	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AciM339_1052	ENOG4107QJQ	Mate efflux family protein
AciM339_1056	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AciM339_1057	ENOG4105NBF	ammecr1 domain protein
AciM339_1058	ENOG4105CD3	dihydroorotase
AciM339_1065	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AciM339_1068	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AciM339_1069	ENOG4105DDK	oxidoreductase, beta subunit
AciM339_1070	ENOG4105DY8	decarboxylase
AciM339_1071	ENOG4105C5F	glutamine synthetase
AciM339_1072	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AciM339_1073	ENOG4105CN9	Peptidase m42 family protein
AciM339_1077	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AciM339_1081	ENOG4105C31	Tryptophanyl-tRNA synthetase
AciM339_1083	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AciM339_1089	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AciM339_1093	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AciM339_1096	ENOG4105CGP	Urocanate hydratase
AciM339_1098	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AciM339_1100	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AciM339_1101	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AciM339_1102	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AciM339_1104	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AciM339_1105	ENOG41082SA	50s ribosomal protein l29
AciM339_1107	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AciM339_1108	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AciM339_1109	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AciM339_1111	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AciM339_1112	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AciM339_1113	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AciM339_1114	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AciM339_1118	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AciM339_1119	ENOG4105VPB	50S ribosomal protein L30
AciM339_1124	ENOG4107RB4	Cytidine monophosphate kinase
AciM339_1132	ENOG4105D44	asparaginase
AciM339_1134	ENOG41086B8	CoB-CoM heterodisulfide reductase
AciM339_1140	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AciM339_1143	ENOG4105C6K	Malic enzyme
AciM339_1144	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AciM339_1145	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AciM339_1146	ENOG4106DSS	Tartrate dehydratase subunit alpha
AciM339_1148	ENOG4108JJB	ABC transporter
AciM339_1149	ENOG4108YZP	cobalt ABC transporter, inner membrane subunit CbiQ
AciM339_1151	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
AciM339_1153	ENOG4105MRR	Transcriptional regulator (By similarity)
AciM339_1154	ENOG4105SC1	monovalent cation H antiporter subunit E
AciM339_1155	ENOG410684G	monovalent cation H antiporter subunit F
AciM339_1156	ENOG4105KJM	monovalent cation h antiporter subunit g
AciM339_1161	ENOG4105D65	subunit l
AciM339_1163	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
AciM339_1164	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AciM339_1165	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AciM339_1166	ENOG4107TDF	Formate hydrogenlyase subunit 4
AciM339_1167	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
AciM339_1168	ENOG4105D1F	ATP-binding protein
AciM339_1172	ENOG4105CQS	hydrogenase expression formation protein HypD
AciM339_1176	ENOG4105C3K	feS assembly ATPase SufC
AciM339_1179	ENOG4108ZVT	methylmalonyl-coA epimerase
AciM339_1181	ENOG4105D8K	carboxyl transferase
AciM339_1184	ENOG4105D9Q	decarboxylase (Beta subunit)
AciM339_1193	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AciM339_1196	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AciM339_1208	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AciM339_1221	ENOG4108JA2	transcriptioN-repair coupling factor
AciM339_1231	ENOG4105CHR	reductase
AciM339_1233	ENOG4105C3M	thioredoxin reductase
AciM339_1241	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AciM339_1242	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AciM339_1243	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AciM339_1244	ENOG4105CAY	ferredoxin--nadp reductase
AciM339_1246	ENOG4105CI2	imidazolone-5-propionate hydrolase
AciM339_1248	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
AciM339_1250	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AciM339_1251	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
AciM339_1252	ENOG4105DFM	M18 family aminopeptidase
AciM339_1253	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
AciM339_1254	ENOG4105CE9	30S ribosomal protein S2
AciM339_1255	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AciM339_1257	ENOG4105C22	threonyL-tRNA synthetase
AciM339_1260	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AciM339_1265	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
AciM339_1269	ENOG4105CQ2	DNA polymerase
AciM339_1272	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AciM339_1277	ENOG4105CN9	Peptidase m42 family protein
AciM339_1280	ENOG41081HM	2'-5' rna ligase
AciM339_1281	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AciM339_1282	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AciM339_1287	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AciM339_1289	ENOG4105QUK	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AciM339_1290	ENOG4105CFG	Acts as a chaperone (By similarity)
AciM339_1292	ENOG4105F4P	)-transporter
AciM339_1297	ENOG4105DFA	alanine racemase domain protein
AciM339_1304	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
AciM339_1306	ENOG4105C6T	cysteine synthase
AciM339_1307	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AciM339_1311	ENOG4105DEF	Extracellular solute-binding protein, family 5
AciM339_1312	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AciM339_1313	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AciM339_1315	ENOG4108JQ7	(ABC) transporter
AciM339_1323	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
AciM339_1324	ENOG4108JJB	ABC transporter
AciM339_1326	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AciM339_1327	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AciM339_1331	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AciM339_1332	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AciM339_1333	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AciM339_1336	ENOG4107QSA	Oxaloacetate decarboxylase
AciM339_1340	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AciM339_1343	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AciM339_1344	ENOG4105HDK	L-asparaginase
AciM339_1345	ENOG4107QRT	dEAD DEAH box helicase
AciM339_1346	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AciM339_1347	ENOG4105D82	Glutamate dehydrogenase
AciM339_1349	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AciM339_1363	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AciM339_1364	ENOG4105D64	Mechanosensitive ion channel
AciM339_1365	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AciM339_1370	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AciM339_1377	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AciM339_1392	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AciM339_1400	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AciM339_1401	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AciM339_1402	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AciM339_1406	ENOG4107YR5	Diacylglycerol kinase
AciM339_1413	ENOG4107QNG	Phosphoribosylglycinamide synthetase
AciM339_1415	ENOG4105E3H	phosphoglycerate mutase
AciM339_1431	ENOG4108F3G	Type I restriction-modification system, R subunit
AciM339_1432	ENOG41080S5	HTH_DTXR
AciM339_1433	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
AciM339_1435	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AciM339_1437	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AciM339_1440	ENOG4105CK7	Sodium proline symporter
AciM339_1442	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
AciM339_1444	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AciM339_1447	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
AciM339_1448	ENOG4105CXT	aspartate transcarbamylase
AciM339_1453	ENOG4105EAH	synthase
AciM339_1457	ENOG4105CJ1	ABC, transporter
AciM339_1458	ENOG4105DCI	Phosphohydrolase
AciM339_1459	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AciM339_1460	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AciM339_1462	ENOG4105CCS	Glutamate formiminotransferase
AciM339_1463	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AciM339_1466	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AciM339_1471	ENOG4107R56	PP-loop domain protein
AciM339_1474	ENOG4105CJ3	phosphate transporter
AciM339_1479	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AciM339_1482	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AciM339_1483	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AciM339_1487	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AciM339_1493	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AciM339_1495	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AciM339_1502	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
AciM339_1503	ENOG4105C4K	Nad synthetase
AciM339_1510	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
AciM339_1511	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
AciM339_1520	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
AciM339_1521	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
AciM339_1527	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AciM339_1529	ENOG4107YTP	response regulator receiver protein
AciM339_1533	ENOG4105C5F	glutamine synthetase
AciM339_1535	ENOG4108JQ1	Dehydrogenase
AciM339_1536	ENOG4105C5R	Aminotransferase
AciM339_1539	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AciM339_1540	ENOG4105D1H	recombination factor protein RarA
AciM339_1547	ENOG4108IUQ	atp-dependent protease
AciM339_1552	ENOG41066FR	extracellular solute-binding protein
AciM339_1553	ENOG4108I5D	sulfate abc transporter
AciM339_1554	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AciM339_1559	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AciM339_1560	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AciM339_1561	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AciM339_1562	ENOG4108IUQ	atp-dependent protease
AciM339_1563	ENOG4105KG3	cytidine deaminase
AciM339_1566	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AciM339_1568	ENOG4108NGU	Transcriptional regulator
AciM339_1569	ENOG410812K	response regulator receiver protein
AciM339_1571	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AciM339_1573	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AciM339_1577	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AciM339_1578	ENOG41079KZ	Major Facilitator Superfamily
AciM339_1579	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AciM339_1580	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)