locus-tag	class	description
AciM339_0003	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AciM339_0004	COG0010	Belongs to the arginase family
AciM339_0012	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AciM339_0021	COG2409	Drug exporters of the RND superfamily
AciM339_0023	COG1473	amidohydrolase
AciM339_0030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AciM339_0039	COG0306	phosphate transporter
AciM339_0041	COG1982	Orn Lys Arg decarboxylase major
AciM339_0045	COG2814	Major facilitator Superfamily
AciM339_0046	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AciM339_0051	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AciM339_0057	COG0124	histidyl-tRNA synthetase
AciM339_0058	COG0534	Mate efflux family protein
AciM339_0060	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AciM339_0060	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AciM339_0062	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AciM339_0063	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AciM339_0064	COG2252	PERMEase
AciM339_0065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AciM339_0069	COG0668	transmembrane transport
AciM339_0070	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AciM339_0071	COG1342	Belongs to the UPF0251 family
AciM339_0079	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AciM339_0082	COG0417	DNA replication proofreading
AciM339_0083	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AciM339_0085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AciM339_0091	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AciM339_0092	COG0047	phosphoribosylformylglycinamidine synthase activity
AciM339_0094	COG2151	metal-sulfur cluster biosynthetic enzyme
AciM339_0100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AciM339_0103	COG1028	Short-chain dehydrogenase reductase Sdr
AciM339_0107	COG1141	Ferredoxin
AciM339_0111	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AciM339_0113	COG0501	Belongs to the peptidase M48B family
AciM339_0118	COG0436	Aminotransferase
AciM339_0120	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AciM339_0122	COG0584	glycerophosphoryl diester phosphodiesterase
AciM339_0124	COG0450	alkyl hydroperoxide reductase
AciM339_0125	COG0557	exoribonuclease II activity
AciM339_0127	COG2033	superoxide reductase activity
AciM339_0128	COG1528	Iron-storage protein
AciM339_0130	COG1592	Rubrerythrin
AciM339_0131	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AciM339_0133	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AciM339_0134	COG0426	domain, Protein
AciM339_0135	COG1773	rubredoxin
AciM339_0137	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AciM339_0137	COG1773	rubredoxin
AciM339_0138	COG1522	sequence-specific DNA binding
AciM339_0139	COG1489	DNA binding
AciM339_0141	COG1051	belongs to the nudix hydrolase family
AciM339_0142	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AciM339_0145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AciM339_0146	COG0081	regulation of translation
AciM339_0147	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AciM339_0153	COG0488	(ABC) transporter
AciM339_0155	COG0138	bifunctional purine biosynthesis protein purh
AciM339_0158	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AciM339_0159	COG0017	Asparaginyl-tRNA synthetase
AciM339_0160	COG4608	Belongs to the ABC transporter superfamily
AciM339_0161	COG0444	Belongs to the ABC transporter superfamily
AciM339_0162	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AciM339_0163	COG0601	transmembrane transport
AciM339_0168	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AciM339_0182	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AciM339_0214	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AciM339_0236	COG1051	belongs to the nudix hydrolase family
AciM339_0236	COG1056	cytidyltransferase-related domain
AciM339_0237	COG1546	Belongs to the CinA family
AciM339_0237	COG1058	Belongs to the CinA family
AciM339_0238	COG0167	dihydroorotate dehydrogenase activity
AciM339_0239	COG0543	2 iron, 2 sulfur cluster binding
AciM339_0245	COG2894	cell division
AciM339_0247	COG0708	Exodeoxyribonuclease III
AciM339_0249	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AciM339_0250	COG0187	DNA topoisomerase II activity
AciM339_0256	COG1793	dna ligase
AciM339_0260	COG0649	NAD binding
AciM339_0261	COG0651	ATP synthesis coupled electron transport
AciM339_0263	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AciM339_0264	COG2414	aldehyde ferredoxin oxidoreductase
AciM339_0267	COG0402	S-adenosylhomocysteine deaminase activity
AciM339_0268	COG3383	formate dehydrogenase (NAD+) activity
AciM339_0269	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AciM339_0270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AciM339_0281	COG0072	phenylalanine-tRNA ligase activity
AciM339_0283	COG0297	glycogen (starch) synthase activity
AciM339_0284	COG0504	CTP synthase activity
AciM339_0286	COG0430	RNA-3'-phosphate cyclase activity
AciM339_0287	COG0705	Rhomboid family
AciM339_0287	COG0457	Tetratricopeptide repeat
AciM339_0288	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AciM339_0291	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AciM339_0295	COG0109	protoheme IX farnesyltransferase activity
AciM339_0296	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AciM339_0299	COG0037	tRNA processing
AciM339_0304	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AciM339_0307	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AciM339_0308	COG0009	L-threonylcarbamoyladenylate synthase
AciM339_0309	COG0024	Methionine aminopeptidase
AciM339_0316	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AciM339_0319	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AciM339_0327	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AciM339_0328	COG0535	radical SAM domain protein
AciM339_0330	COG0516	GMP reductase activity
AciM339_0330	COG0517	IMP dehydrogenase activity
AciM339_0331	COG0423	glycine-tRNA ligase activity
AciM339_0333	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AciM339_0334	COG0156	8-amino-7-oxononanoate synthase activity
AciM339_0337	COG0442	prolyl-tRNA aminoacylation
AciM339_0340	COG1304	FMN binding
AciM339_0343	COG0312	modulator of DNA gyrase
AciM339_0344	COG0312	modulator of DNA gyrase
AciM339_0346	COG2986	histidine ammonia-lyase
AciM339_0349	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AciM339_0353	COG3959	Transketolase, thiamine diphosphate binding domain
AciM339_0354	COG3958	Transketolase
AciM339_0355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AciM339_0357	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AciM339_0358	COG0025	NhaP-type Na H and K H
AciM339_0360	COG0163	prenyltransferase activity
AciM339_0361	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AciM339_0364	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AciM339_0364	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AciM339_0366	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AciM339_0367	COG1522	sequence-specific DNA binding
AciM339_0375	COG4974	Belongs to the 'phage' integrase family
AciM339_0377	COG0720	synthase
AciM339_0380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AciM339_0381	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AciM339_0385	COG2264	protein methyltransferase activity
AciM339_0390	COG2095	MarC family integral membrane protein
AciM339_0398	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AciM339_0400	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AciM339_0416	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AciM339_0419	COG2223	nitrite transmembrane transporter activity
AciM339_0425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AciM339_0427	COG0126	phosphoglycerate kinase activity
AciM339_0428	COG0598	Magnesium transport protein CorA
AciM339_0429	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AciM339_0429	COG0519	Catalyzes the synthesis of GMP from XMP
AciM339_0432	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AciM339_0441	COG2379	hydroxypyruvate reductase
AciM339_0446	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AciM339_0448	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AciM339_0451	COG1695	Transcriptional regulator
AciM339_0456	COG2140	Oxalate decarboxylase
AciM339_0457	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AciM339_0461	COG0436	Aminotransferase
AciM339_0468	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AciM339_0480	COG0546	phosphoglycolate phosphatase activity
AciM339_0493	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AciM339_0495	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AciM339_0497	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AciM339_0499	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AciM339_0502	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AciM339_0503	COG0569	domain protein
AciM339_0508	COG0012	GTP binding
AciM339_0510	COG0371	Dehydrogenase
AciM339_0514	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AciM339_0519	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AciM339_0520	COG0489	protein tyrosine kinase activity
AciM339_0526	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AciM339_0537	COG2255	four-way junction helicase activity
AciM339_0540	COG0330	HflC and HflK could
AciM339_0544	COG1945	arginine decarboxylase activity
AciM339_0546	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AciM339_0555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AciM339_0556	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AciM339_0556	COG0519	Catalyzes the synthesis of GMP from XMP
AciM339_0560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AciM339_0561	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AciM339_0562	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AciM339_0564	COG1136	(ABC) transporter
AciM339_0567	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
AciM339_0571	COG1994	Peptidase M50
AciM339_0572	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AciM339_0573	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AciM339_0578	COG0017	Asparaginyl-tRNA synthetase
AciM339_0587	COG1028	Short-chain dehydrogenase reductase Sdr
AciM339_0590	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AciM339_0591	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AciM339_0592	COG1515	deoxyribonuclease V activity
AciM339_0593	COG1739	Uncharacterized protein family UPF0029
AciM339_0595	COG0006	proline dipeptidase activity
AciM339_0604	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AciM339_0614	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AciM339_0614	COG1918	ferrous iron import across plasma membrane
AciM339_0616	COG1980	fructose-bisphosphate aldolase activity
AciM339_0620	COG0215	cysteine-tRNA ligase activity
AciM339_0621	COG2414	aldehyde ferredoxin oxidoreductase
AciM339_0623	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AciM339_0631	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AciM339_0632	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AciM339_0635	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AciM339_0637	COG4608	Belongs to the ABC transporter superfamily
AciM339_0638	COG0444	Belongs to the ABC transporter superfamily
AciM339_0641	COG0747	negative chemotaxis
AciM339_0647	COG0322	excinuclease ABC activity
AciM339_0648	COG1129	ABC transporter
AciM339_0652	COG1506	peptidase
AciM339_0652	COG0823	Involved in the tonB-independent uptake of proteins
AciM339_0652	COG4946	Tricorn protease homolog
AciM339_0655	COG1863	multisubunit Na H antiporter MnhE subunit
AciM339_0656	COG2212	antiporter activity
AciM339_0659	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AciM339_0659	COG2111	Na H antiporter
AciM339_0660	COG1006	Multisubunit Na H antiporter MnhC subunit
AciM339_0661	COG0651	ATP synthesis coupled electron transport
AciM339_0662	COG0651	ATP synthesis coupled electron transport
AciM339_0663	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AciM339_0664	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AciM339_0665	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AciM339_0666	COG0649	NAD binding
AciM339_0667	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AciM339_0671	COG0300	oxidoreductase activity
AciM339_0678	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AciM339_0682	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AciM339_0683	COG0157	Belongs to the NadC ModD family
AciM339_0686	COG0574	Belongs to the PEP-utilizing enzyme family
AciM339_0686	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AciM339_0692	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AciM339_0692	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AciM339_0694	COG0501	Belongs to the peptidase M48B family
AciM339_0702	COG2131	deaminase
AciM339_0705	COG0714	Associated with various cellular activities
AciM339_0715	COG4974	Belongs to the 'phage' integrase family
AciM339_0717	COG0183	Belongs to the thiolase family
AciM339_0718	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AciM339_0719	COG0396	ATPase activity
AciM339_0720	COG0719	Fe-S assembly protein
AciM339_0721	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AciM339_0723	COG0803	Belongs to the bacterial solute-binding protein 9 family
AciM339_0726	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AciM339_0729	COG0517	IMP dehydrogenase activity
AciM339_0729	COG0516	GMP reductase activity
AciM339_0732	COG0475	glutathione-regulated potassium exporter activity
AciM339_0737	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AciM339_0737	COG1042	CoA-binding domain protein
AciM339_0737	COG0045	succinate-CoA ligase (ADP-forming) activity
AciM339_0741	COG1137	ATPase activity
AciM339_0744	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AciM339_0744	COG1042	CoA-binding domain protein
AciM339_0744	COG0045	succinate-CoA ligase (ADP-forming) activity
AciM339_0745	COG1042	CoA-binding domain protein
AciM339_0745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AciM339_0745	COG0045	succinate-CoA ligase (ADP-forming) activity
AciM339_0755	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AciM339_0758	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AciM339_0762	COG1144	Oxidoreductase
AciM339_0763	COG1013	pyruvate-flavodoxin oxidoreductase activity
AciM339_0764	COG0674	pyruvate-flavodoxin oxidoreductase activity
AciM339_0767	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AciM339_0770	COG1047	Peptidyl-prolyl cis-trans
AciM339_0773	COG2814	Major facilitator Superfamily
AciM339_0774	COG0303	'Molybdopterin
AciM339_0779	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AciM339_0782	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AciM339_0783	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AciM339_0785	COG0531	amino acid
AciM339_0788	COG1131	(ABC) transporter
AciM339_0789	COG0842	Transport permease protein
AciM339_0794	COG1213	nucleotidyl transferase
AciM339_0795	COG0367	asparagine synthase
AciM339_0796	COG1373	ATPase (AAA superfamily
AciM339_0803	COG0438	transferase activity, transferring glycosyl groups
AciM339_0805	COG0438	transferase activity, transferring glycosyl groups
AciM339_0808	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AciM339_0811	COG1181	Belongs to the D-alanine--D-alanine ligase family
AciM339_0813	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AciM339_0814	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AciM339_0815	COG0673	inositol 2-dehydrogenase activity
AciM339_0825	COG2094	Belongs to the DNA glycosylase MPG family
AciM339_0829	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AciM339_0830	COG0546	phosphoglycolate phosphatase activity
AciM339_0831	COG1028	Short-chain dehydrogenase reductase Sdr
AciM339_0835	COG1444	tRNA N-acetyltransferase activity
AciM339_0839	COG4948	Mandelate Racemase Muconate Lactonizing
AciM339_0842	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AciM339_0844	COG1760	l-serine dehydratase
AciM339_0845	COG1760	l-serine dehydratase
AciM339_0846	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AciM339_0847	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AciM339_0849	COG0066	3-isopropylmalate dehydratase activity
AciM339_0850	COG1201	RNA secondary structure unwinding
AciM339_0854	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AciM339_0861	COG2255	four-way junction helicase activity
AciM339_0862	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AciM339_0863	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AciM339_0867	COG1185	polyribonucleotide nucleotidyltransferase activity
AciM339_0868	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AciM339_0869	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AciM339_0871	COG0456	acetyltransferase
AciM339_0876	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AciM339_0881	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AciM339_0881	COG0473	3-isopropylmalate dehydrogenase activity
AciM339_0890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AciM339_0891	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AciM339_0892	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AciM339_0894	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AciM339_0896	COG0116	Belongs to the methyltransferase superfamily
AciM339_0919	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AciM339_0920	COG0066	3-isopropylmalate dehydratase activity
AciM339_0921	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AciM339_0923	COG1121	(ABC) transporter
AciM339_0926	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AciM339_0928	COG3850	Histidine kinase
AciM339_0928	COG5002	protein histidine kinase activity
AciM339_0929	COG1573	uracil-dna glycosylase
AciM339_0930	COG2151	metal-sulfur cluster biosynthetic enzyme
AciM339_0931	COG0730	response to heat
AciM339_0933	COG0006	proline dipeptidase activity
AciM339_0939	COG0352	thiamine-phosphate diphosphorylase activity
AciM339_0948	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AciM339_0949	COG0584	glycerophosphoryl diester phosphodiesterase
AciM339_0955	COG0587	DNA-directed DNA polymerase activity
AciM339_0956	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AciM339_0957	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AciM339_0958	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AciM339_0963	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AciM339_0966	COG0543	2 iron, 2 sulfur cluster binding
AciM339_0967	COG0493	'glutamate synthase
AciM339_0967	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AciM339_0972	COG0483	inositol monophosphate 1-phosphatase activity
AciM339_0973	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AciM339_0977	COG0051	transcription antitermination factor activity, RNA binding
AciM339_0978	COG2895	sulfate adenylyltransferase (ATP) activity
AciM339_0979	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AciM339_0980	COG0049	tRNA binding
AciM339_0987	COG0243	molybdopterin cofactor binding
AciM339_0988	COG0693	protein deglycase activity
AciM339_0989	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AciM339_0992	COG0674	pyruvate-flavodoxin oxidoreductase activity
AciM339_0998	COG0765	amino acid transport
AciM339_0999	COG1126	abc transporter atp-binding protein
AciM339_1001	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AciM339_1004	COG1110	DNA topoisomerase II activity
AciM339_1008	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AciM339_1009	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AciM339_1011	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AciM339_1012	COG0446	pyridine nucleotide-disulphide oxidoreductase
AciM339_1016	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
AciM339_1020	COG0004	ammonium transporteR
AciM339_1023	COG2301	Belongs to the HpcH HpaI aldolase family
AciM339_1028	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AciM339_1029	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AciM339_1030	COG0200	Binds to the 23S rRNA
AciM339_1034	COG0495	leucyl-tRNA aminoacylation
AciM339_1036	COG0671	phosphoesterase, PA-phosphatase related
AciM339_1037	COG0402	S-adenosylhomocysteine deaminase activity
AciM339_1038	COG0372	Belongs to the citrate synthase family
AciM339_1040	COG0066	3-isopropylmalate dehydratase activity
AciM339_1042	COG0473	3-isopropylmalate dehydrogenase activity
AciM339_1046	COG0494	nUDIX hydrolase
AciM339_1050	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AciM339_1052	COG0534	Mate efflux family protein
AciM339_1056	COG0602	queuosine metabolic process
AciM339_1057	COG2078	PFAM AMMECR1 domain protein
AciM339_1058	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AciM339_1065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AciM339_1068	COG0674	pyruvate-flavodoxin oxidoreductase activity
AciM339_1069	COG1013	pyruvate-flavodoxin oxidoreductase activity
AciM339_1070	COG0076	glutamate decarboxylase activity
AciM339_1071	COG0174	glutamine synthetase
AciM339_1072	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AciM339_1073	COG1363	Peptidase, m42
AciM339_1081	COG0180	Tryptophanyl-tRNA synthetase
AciM339_1083	COG1234	tRNA 3'-trailer cleavage
AciM339_1086	COG0579	oxidoreductase
AciM339_1089	COG0823	Involved in the tonB-independent uptake of proteins
AciM339_1089	COG1506	peptidase
AciM339_1089	COG4946	Tricorn protease homolog
AciM339_1093	COG0101	tRNA pseudouridine synthase activity
AciM339_1096	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AciM339_1098	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AciM339_1102	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AciM339_1104	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AciM339_1105	COG0255	Belongs to the universal ribosomal protein uL29 family
AciM339_1107	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AciM339_1108	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AciM339_1109	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AciM339_1111	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AciM339_1112	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AciM339_1113	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AciM339_1114	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AciM339_1118	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AciM339_1119	COG1841	ribosomal large subunit assembly
AciM339_1124	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AciM339_1134	COG2048	Heterodisulfide reductase, subunit B
AciM339_1140	COG1053	succinate dehydrogenase
AciM339_1143	COG0281	malic enzyme
AciM339_1144	COG0045	succinate-CoA ligase (ADP-forming) activity
AciM339_1145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AciM339_1146	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AciM339_1148	COG1122	ATPase activity
AciM339_1149	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AciM339_1151	COG0310	cobalt ion transport
AciM339_1153	COG0864	Transcriptional regulator
AciM339_1154	COG1863	multisubunit Na H antiporter MnhE subunit
AciM339_1155	COG2212	antiporter activity
AciM339_1156	COG1320	monovalent cation:proton antiporter activity
AciM339_1163	COG3260	NADH ubiquinone oxidoreductase 20
AciM339_1164	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AciM339_1164	COG0649	NAD binding
AciM339_1165	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AciM339_1165	COG3261	NADH dehydrogenase
AciM339_1166	COG0650	Formate hydrogenlyase subunit 4
AciM339_1167	COG4656	Part of a membrane complex involved in electron transport
AciM339_1168	COG0489	protein tyrosine kinase activity
AciM339_1171	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AciM339_1172	COG0409	Hydrogenase expression formation protein
AciM339_1173	COG0298	carbon dioxide binding
AciM339_1176	COG0396	ATPase activity
AciM339_1179	COG0346	lactoylglutathione lyase activity
AciM339_1181	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AciM339_1184	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AciM339_1193	COG1196	nuclear chromosome segregation
AciM339_1196	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AciM339_1201	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AciM339_1208	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AciM339_1221	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AciM339_1231	COG1028	Short-chain dehydrogenase reductase Sdr
AciM339_1233	COG0492	ferredoxin-NADP+ reductase activity
AciM339_1241	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AciM339_1243	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AciM339_1244	COG0492	ferredoxin-NADP+ reductase activity
AciM339_1246	COG1228	amidohydrolase
AciM339_1248	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
AciM339_1250	COG0315	cyclic pyranopterin monophosphate synthase activity
AciM339_1251	COG0521	Mo-molybdopterin cofactor biosynthetic process
AciM339_1252	COG1362	aminopeptidase activity
AciM339_1253	COG1355	regulation of microtubule-based process
AciM339_1254	COG0052	Belongs to the universal ribosomal protein uS2 family
AciM339_1255	COG0148	phosphopyruvate hydratase activity
AciM339_1257	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AciM339_1260	COG0516	GMP reductase activity
AciM339_1260	COG0517	IMP dehydrogenase activity
AciM339_1265	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AciM339_1269	COG0417	DNA replication proofreading
AciM339_1272	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AciM339_1280	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AciM339_1281	COG0509	glycine decarboxylation via glycine cleavage system
AciM339_1282	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AciM339_1285	COG0572	uridine kinase
AciM339_1289	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AciM339_1292	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AciM339_1299	COG1269	ATP hydrolysis coupled proton transport
AciM339_1306	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AciM339_1307	COG0552	protein localization to endoplasmic reticulum
AciM339_1311	COG0747	negative chemotaxis
AciM339_1313	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AciM339_1314	COG0444	Belongs to the ABC transporter superfamily
AciM339_1315	COG4608	Belongs to the ABC transporter superfamily
AciM339_1323	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AciM339_1324	COG1122	ATPase activity
AciM339_1326	COG0585	pseudouridine synthase activity
AciM339_1327	COG0105	UTP biosynthetic process
AciM339_1331	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AciM339_1332	COG1227	inorganic diphosphatase activity
AciM339_1332	COG0517	IMP dehydrogenase activity
AciM339_1333	COG0312	modulator of DNA gyrase
AciM339_1334	COG0312	modulator of DNA gyrase
AciM339_1340	COG1213	nucleotidyl transferase
AciM339_1340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AciM339_1343	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AciM339_1344	COG0252	asparaginase activity
AciM339_1345	COG1201	RNA secondary structure unwinding
AciM339_1346	COG2255	four-way junction helicase activity
AciM339_1347	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AciM339_1349	COG2943	transferase activity, transferring hexosyl groups
AciM339_1363	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AciM339_1364	COG0668	transmembrane transport
AciM339_1365	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AciM339_1370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AciM339_1377	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AciM339_1392	COG1850	ribulose-bisphosphate carboxylase activity
AciM339_1394	COG1396	sequence-specific DNA binding
AciM339_1400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AciM339_1401	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AciM339_1402	COG0085	RNA polymerase activity
AciM339_1406	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AciM339_1413	COG0151	Belongs to the GarS family
AciM339_1415	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
AciM339_1432	COG1321	iron dependent repressor
AciM339_1433	COG0095	Lipoate-protein ligase
AciM339_1435	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AciM339_1435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AciM339_1437	COG0301	tRNA thio-modification
AciM339_1440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AciM339_1442	COG2414	aldehyde ferredoxin oxidoreductase
AciM339_1444	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AciM339_1447	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AciM339_1448	COG0540	Belongs to the ATCase OTCase family
AciM339_1453	COG0142	geranyltranstransferase activity
AciM339_1457	COG1131	(ABC) transporter
AciM339_1458	COG1078	dGTPase activity
AciM339_1459	COG0459	protein refolding
AciM339_1460	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AciM339_1463	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AciM339_1466	COG0284	orotidine-5'-phosphate decarboxylase activity
AciM339_1471	COG0037	tRNA processing
AciM339_1474	COG0306	phosphate transporter
AciM339_1479	COG1185	polyribonucleotide nucleotidyltransferase activity
AciM339_1482	COG0731	radical SAM domain protein
AciM339_1482	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AciM339_1483	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AciM339_1487	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AciM339_1495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AciM339_1502	COG2414	aldehyde ferredoxin oxidoreductase
AciM339_1503	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AciM339_1507	COG0525	valine-tRNA ligase activity
AciM339_1510	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AciM339_1511	COG1518	maintenance of DNA repeat elements
AciM339_1520	COG0647	UMP catabolic process
AciM339_1521	COG0179	Fumarylacetoacetate (FAA) hydrolase
AciM339_1527	COG0528	UMP kinase activity
AciM339_1529	COG2201	protein-glutamate methylesterase activity
AciM339_1533	COG0174	glutamine synthetase
AciM339_1535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AciM339_1536	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AciM339_1539	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AciM339_1540	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AciM339_1540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AciM339_1544	COG0170	dolichyl monophosphate biosynthetic process
AciM339_1547	COG0470	DNA polymerase III
AciM339_1547	COG1067	ATP-dependent peptidase activity
AciM339_1552	COG0725	ABC transporter, periplasmic molybdate-binding protein
AciM339_1554	COG3842	ATPase activity
AciM339_1559	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AciM339_1560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AciM339_1561	COG0358	DNA primase activity
AciM339_1562	COG0470	DNA polymerase III
AciM339_1562	COG1067	ATP-dependent peptidase activity
AciM339_1563	COG0295	cytidine deaminase activity
AciM339_1566	COG0544	peptidyl-prolyl cis-trans isomerase activity
AciM339_1568	COG1378	Sugar-specific transcriptional regulator TrmB
AciM339_1569	COG2204	response regulator
AciM339_1571	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AciM339_1573	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AciM339_1573	COG2050	protein possibly involved in aromatic compounds catabolism
AciM339_1577	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AciM339_1578	COG0477	Major facilitator Superfamily
AciM339_1579	COG0285	dihydrofolate synthase activity
AciM339_1580	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis