locus-tag	class	description
EI070_00010	COG0592	DNA-directed DNA polymerase activity
EI070_00020	COG0187	DNA topoisomerase II activity
EI070_00030	COG0586	Pfam SNARE associated Golgi protein
EI070_00035	COG0488	(ABC) transporter
EI070_00060	COG0596	Alpha beta hydrolase
EI070_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EI070_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EI070_00115	COG0733	neurotransmitter:sodium symporter activity
EI070_00155	COG2233	PERMEase
EI070_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI070_00205	COG2814	Major facilitator Superfamily
EI070_00210	COG0656	L-ascorbic acid biosynthetic process
EI070_00215	COG0583	DNA-binding transcription factor activity
EI070_00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI070_00235	COG1064	alcohol dehydrogenase
EI070_00240	COG2818	Glycosylase
EI070_00255	COG1194	a g-specific adenine glycosylase
EI070_00275	COG2983	Belongs to the UPF0260 family
EI070_00280	COG2133	pyrroloquinoline quinone binding
EI070_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EI070_00290	COG2116	formate transmembrane transporter activity
EI070_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EI070_00315	COG1335	isochorismatase
EI070_00320	COG0385	Bile acid
EI070_00325	COG0534	Mate efflux family protein
EI070_00330	COG1683	Conserved Protein
EI070_00350	COG0625	glutathione transferase activity
EI070_00360	COG1113	amino acid transport
EI070_00370	COG0523	cobalamin synthesis protein
EI070_00380	COG2188	Transcriptional regulator
EI070_00410	COG0010	Belongs to the arginase family
EI070_00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EI070_00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EI070_00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EI070_00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EI070_00550	COG0534	Mate efflux family protein
EI070_00555	COG0436	Aminotransferase
EI070_00560	COG2733	membrane
EI070_00575	COG2918	glutathione biosynthetic process
EI070_00585	COG3501	Rhs element vgr protein
EI070_00590	COG0791	NLP P60 protein
EI070_00590	COG1388	LysM domain
EI070_00610	COG3150	esterase
EI070_00620	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_00625	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EI070_00635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EI070_00645	COG2233	PERMEase
EI070_00650	COG2351	hydroxyisourate hydrolase activity
EI070_00685	COG3706	GGDEF domain
EI070_00700	COG1393	Belongs to the ArsC family
EI070_00705	COG0708	Exodeoxyribonuclease III
EI070_00725	COG0189	ligase activity
EI070_00745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EI070_00755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EI070_00770	COG4942	peptidase
EI070_00780	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI070_00790	COG2119	membrane
EI070_00810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI070_00810	COG0426	domain, Protein
EI070_00835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EI070_00855	COG1902	pentaerythritol trinitrate reductase activity
EI070_00860	COG1519	Transferase
EI070_00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EI070_00870	COG0668	transmembrane transport
EI070_00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EI070_00885	COG1335	isochorismatase
EI070_00890	COG1522	sequence-specific DNA binding
EI070_00895	COG3328	transposase activity
EI070_00920	COG2205	protein histidine kinase activity
EI070_00920	COG0784	Response regulator, receiver
EI070_00920	COG2198	Histidine kinase
EI070_00925	COG3162	membrane
EI070_00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EI070_00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EI070_00950	COG3706	GGDEF domain
EI070_00960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EI070_00965	COG1309	transcriptional regulator
EI070_00985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EI070_00985	COG0352	thiamine-phosphate diphosphorylase activity
EI070_00985	COG0351	phosphomethylpyrimidine kinase
EI070_00995	COG2814	Major facilitator Superfamily
EI070_01010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EI070_01020	COG1113	amino acid transport
EI070_01030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EI070_01035	COG1012	belongs to the aldehyde dehydrogenase family
EI070_01045	COG1335	isochorismatase
EI070_01075	COG2814	Major facilitator Superfamily
EI070_01080	COG0583	DNA-binding transcription factor activity
EI070_01100	COG0667	Aldo Keto reductase
EI070_01135	COG1733	regulation of RNA biosynthetic process
EI070_01145	COG2249	NAD(P)H dehydrogenase (quinone) activity
EI070_01210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EI070_01225	COG2329	Antibiotic biosynthesis monooxygenase
EI070_01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EI070_01285	COG0427	acetyl-CoA hydrolase
EI070_01300	COG0745	RESPONSE REGULATOR receiver
EI070_01310	COG0659	secondary active sulfate transmembrane transporter activity
EI070_01315	COG4221	oxidoreductase activity
EI070_01325	COG0488	(ABC) transporter
EI070_01410	COG0833	amino acid
EI070_01455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EI070_01460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EI070_01475	COG2226	methyltransferase
EI070_01525	COG0070	glutamate synthase
EI070_01525	COG0069	glutamate synthase activity
EI070_01525	COG0067	glutamate synthase
EI070_01530	COG0493	'glutamate synthase
EI070_01540	COG1704	LemA family
EI070_01545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EI070_01565	COG3307	-O-antigen
EI070_01585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EI070_01600	COG0194	GDP metabolic process
EI070_01650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EI070_01670	COG5380	lipid catabolic process
EI070_01675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EI070_01700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EI070_01705	COG0277	FAD linked oxidase domain protein
EI070_01715	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EI070_01720	COG2249	NAD(P)H dehydrogenase (quinone) activity
EI070_01735	COG1289	transmembrane transporter activity
EI070_01745	COG0628	permease
EI070_01750	COG1192	Involved in chromosome partitioning
EI070_01780	COG0833	amino acid
EI070_01785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EI070_01790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EI070_01800	COG1012	belongs to the aldehyde dehydrogenase family
EI070_01840	COG0583	DNA-binding transcription factor activity
EI070_01885	COG0517	IMP dehydrogenase activity
EI070_01890	COG1983	PspC domain protein
EI070_01900	COG1960	acyl-CoA dehydrogenase activity
EI070_01915	COG0408	coproporphyrinogen oxidase activity
EI070_01935	COG0513	Belongs to the DEAD box helicase family
EI070_01945	COG1127	ABC transporter
EI070_01950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EI070_01960	COG2854	intermembrane phospholipid transfer
EI070_01970	COG0598	Magnesium transport protein CorA
EI070_01980	COG0494	nUDIX hydrolase
EI070_01985	COG1040	competence protein
EI070_01990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EI070_02010	COG1946	Acyl-CoA thioesterase
EI070_02015	COG1301	dicarboxylic acid transport
EI070_02030	COG1959	2 iron, 2 sulfur cluster binding
EI070_02035	COG1017	nitric oxide dioxygenase activity
EI070_02035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EI070_02040	COG0433	COG0433 Predicted ATPase
EI070_02045	COG0626	cystathionine gamma-synthase activity
EI070_02165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EI070_02175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EI070_02200	COG1960	acyl-CoA dehydrogenase activity
EI070_02205	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EI070_02235	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EI070_02240	COG0339	signal peptide processing
EI070_02245	COG0557	exoribonuclease II activity
EI070_02290	COG0179	Fumarylacetoacetate (FAA) hydrolase
EI070_02295	COG2169	Transcriptional regulator
EI070_02300	COG0697	spore germination
EI070_02305	COG1295	ribonuclease BN
EI070_02340	COG1702	phosphate starvation-inducible protein PhoH
EI070_02350	COG0741	lytic transglycosylase activity
EI070_02350	COG1196	nuclear chromosome segregation
EI070_02350	COG0739	heme binding
EI070_02380	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EI070_02385	COG1183	phosphatidylcholine synthase activity
EI070_02430	COG1960	acyl-CoA dehydrogenase activity
EI070_02435	COG1309	transcriptional regulator
EI070_02450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EI070_02455	COG1960	acyl-CoA dehydrogenase activity
EI070_02475	COG2969	positive regulation of protein catabolic process
EI070_02485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EI070_02500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EI070_02505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EI070_02525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EI070_02535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EI070_02540	COG1408	metallophosphoesterase
EI070_02550	COG2199	diguanylate cyclase activity
EI070_02595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI070_02595	COG3453	Protein conserved in bacteria
EI070_02610	COG1607	acyl-coa hydrolase
EI070_02640	COG2350	Protein conserved in bacteria
EI070_02650	COG0613	PHP domain protein
EI070_02655	COG3781	membrane
EI070_02665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EI070_02670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EI070_02680	COG1862	Preprotein translocase
EI070_02730	COG2205	protein histidine kinase activity
EI070_02735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EI070_02755	COG0726	polysaccharide deacetylase
EI070_02760	COG0463	Glycosyl transferase, family 2
EI070_02765	COG0438	transferase activity, transferring glycosyl groups
EI070_02830	COG0625	glutathione transferase activity
EI070_02835	COG0583	DNA-binding transcription factor activity
EI070_02840	COG1960	acyl-CoA dehydrogenase activity
EI070_02845	COG1960	acyl-CoA dehydrogenase activity
EI070_02855	COG2205	protein histidine kinase activity
EI070_02860	COG0745	RESPONSE REGULATOR receiver
EI070_02865	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EI070_02885	COG2096	Adenosyltransferase
EI070_02900	COG0133	tryptophan synthase activity
EI070_02945	COG0285	dihydrofolate synthase activity
EI070_02965	COG0450	alkyl hydroperoxide reductase
EI070_02980	COG0477	Major facilitator Superfamily
EI070_02985	COG1272	protein, Hemolysin III
EI070_03015	COG0183	Belongs to the thiolase family
EI070_03020	COG2207	Transcriptional regulator
EI070_03040	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI070_03060	COG0183	Belongs to the thiolase family
EI070_03070	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EI070_03070	COG2885	chlorophyll binding
EI070_03080	COG1690	Belongs to the RtcB family
EI070_03085	COG0833	amino acid
EI070_03095	COG2233	PERMEase
EI070_03125	COG2094	Belongs to the DNA glycosylase MPG family
EI070_03130	COG4772	TonB-dependent receptor
EI070_03145	COG1902	pentaerythritol trinitrate reductase activity
EI070_03150	COG0679	Auxin Efflux Carrier
EI070_03160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EI070_03165	COG0354	folic acid binding
EI070_03175	COG3189	MarR family transcriptional regulator
EI070_03180	COG2824	Alkylphosphonate utilization operon protein PhnA
EI070_03185	COG3422	double-strand break repair
EI070_03225	COG0840	transmembrane signaling receptor activity
EI070_03245	COG5510	response to toxic substance
EI070_03255	COG2832	Protein of unknown function (DUF454)
EI070_03260	COG1376	ErfK ybiS ycfS ynhG family protein
EI070_03310	COG1289	transmembrane transporter activity
EI070_03315	COG2814	Major facilitator Superfamily
EI070_03335	COG1115	amino acid carrier protein
EI070_03340	COG1752	Esterase of the alpha-beta hydrolase superfamily
EI070_03345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EI070_03350	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EI070_03380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EI070_03390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EI070_03395	COG1077	Cell shape determining protein MreB Mrl
EI070_03400	COG1792	Involved in formation and maintenance of cell shape
EI070_03405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EI070_03410	COG0424	maF-like protein
EI070_03415	COG1530	ribonuclease E activity
EI070_03425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EI070_03445	COG2249	NAD(P)H dehydrogenase (quinone) activity
EI070_03470	COG2207	Transcriptional regulator
EI070_03490	COG1113	amino acid transport
EI070_03495	COG2828	Protein conserved in bacteria
EI070_03500	COG0142	geranyltranstransferase activity
EI070_03505	COG2315	Protein conserved in bacteria
EI070_03520	COG1752	Esterase of the alpha-beta hydrolase superfamily
EI070_03540	COG2194	sulfuric ester hydrolase activity
EI070_03545	COG0745	RESPONSE REGULATOR receiver
EI070_03550	COG0642	Histidine kinase
EI070_03560	COG0004	ammonium transporteR
EI070_03570	COG0583	DNA-binding transcription factor activity
EI070_03590	COG0525	valine-tRNA ligase activity
EI070_03600	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_03610	COG0393	Putative heavy-metal-binding
EI070_03615	COG0393	Putative heavy-metal-binding
EI070_03620	COG1538	Outer membrane efflux protein
EI070_03630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI070_03635	COG0671	phosphoesterase, PA-phosphatase related
EI070_03665	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EI070_03680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EI070_03680	COG1648	precorrin-2 dehydrogenase activity
EI070_03685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EI070_03690	COG1733	regulation of RNA biosynthetic process
EI070_03700	COG0531	amino acid
EI070_03715	COG0321	lipoyl(octanoyl) transferase activity
EI070_03720	COG2921	Belongs to the UPF0250 family
EI070_03760	COG2009	succinate dehydrogenase
EI070_03765	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EI070_03770	COG1053	succinate dehydrogenase
EI070_03775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EI070_03800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI070_03820	COG2354	Protein conserved in bacteria
EI070_03825	COG2321	neutral zinc metallopeptidase
EI070_03860	COG2843	Capsule synthesis protein
EI070_03875	COG0589	response to stress
EI070_03895	COG0505	Belongs to the CarA family
EI070_03920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EI070_03925	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EI070_03975	COG0477	Major facilitator Superfamily
EI070_03980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EI070_04000	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EI070_04025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI070_04030	COG0584	glycerophosphoryl diester phosphodiesterase
EI070_04050	COG0741	lytic transglycosylase activity
EI070_04075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EI070_04090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EI070_04120	COG0778	Nitroreductase
EI070_04135	COG1929	Belongs to the glycerate kinase type-1 family
EI070_04140	COG0243	molybdopterin cofactor binding
EI070_04145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EI070_04165	COG3339	Conserved Protein
EI070_04175	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EI070_04190	COG1113	amino acid transport
EI070_04200	COG0019	diaminopimelate decarboxylase activity
EI070_04210	COG1280	lysine exporter protein (LysE YggA)
EI070_04215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EI070_04245	COG0463	Glycosyl transferase, family 2
EI070_04265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI070_04295	COG4591	ABC-type transport system involved in lipoprotein release permease component
EI070_04300	COG1136	(ABC) transporter
EI070_04305	COG2333	competence protein COMEC
EI070_04305	COG0658	competence protein
EI070_04315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EI070_04315	COG0616	signal peptide processing
EI070_04320	COG0596	Alpha beta hydrolase
EI070_04325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EI070_04335	COG0628	permease
EI070_04370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI070_04390	COG0823	Involved in the tonB-independent uptake of proteins
EI070_04410	COG0824	Thioesterase
EI070_04415	COG1473	amidohydrolase
EI070_04435	COG0047	phosphoribosylformylglycinamidine synthase activity
EI070_04435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EI070_04440	COG2814	Major facilitator Superfamily
EI070_04445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EI070_04450	COG1024	Enoyl-CoA hydratase
EI070_04455	COG1051	belongs to the nudix hydrolase family
EI070_04455	COG1056	cytidyltransferase-related domain
EI070_04465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EI070_04480	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EI070_04495	COG4625	pathogenesis
EI070_04500	COG0583	DNA-binding transcription factor activity
EI070_04505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EI070_04510	COG4208	sulfate ABC transporter
EI070_04515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EI070_04525	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EI070_04530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EI070_04535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EI070_04575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI070_04590	COG0681	Belongs to the peptidase S26 family
EI070_04605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EI070_04615	COG1381	Involved in DNA repair and RecF pathway recombination
EI070_04620	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EI070_04630	COG4221	oxidoreductase activity
EI070_04680	COG0556	nucleotide-excision repair
EI070_04735	COG2070	2-Nitropropane dioxygenase
EI070_04765	COG1215	transferase activity, transferring glycosyl groups
EI070_04780	COG0415	Belongs to the DNA photolyase family
EI070_04790	COG1252	NADH dehydrogenase
EI070_04795	COG1686	Belongs to the peptidase S11 family
EI070_04810	COG1187	pseudouridine synthase activity
EI070_04835	COG0477	Major facilitator Superfamily
EI070_04840	COG0583	DNA-binding transcription factor activity
EI070_04855	COG0612	Peptidase, M16
EI070_04880	COG0352	thiamine-phosphate diphosphorylase activity
EI070_04915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EI070_04930	COG1309	transcriptional regulator
EI070_04940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EI070_04945	COG0076	glutamate decarboxylase activity
EI070_04955	COG1522	sequence-specific DNA binding
EI070_04960	COG3961	Belongs to the TPP enzyme family
EI070_04965	COG1113	amino acid transport
EI070_04970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EI070_04975	COG0573	inorganic phosphate transmembrane transporter activity
EI070_04985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EI070_04990	COG0616	signal peptide processing
EI070_05025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EI070_05030	COG1686	Belongs to the peptidase S11 family
EI070_05055	COG0583	DNA-binding transcription factor activity
EI070_05060	COG1067	ATP-dependent peptidase activity
EI070_05105	COG1966	Carbon starvation protein
EI070_05110	COG2879	small protein
EI070_05145	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EI070_05145	COG2508	Transcriptional regulator
EI070_05165	COG1113	amino acid transport
EI070_05170	COG0583	DNA-binding transcription factor activity
EI070_05175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EI070_05180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EI070_05195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI070_05200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI070_05200	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EI070_05235	COG2814	Major facilitator Superfamily
EI070_05240	COG4948	Mandelate Racemase Muconate Lactonizing
EI070_05250	COG1309	transcriptional regulator
EI070_05270	COG1741	Belongs to the pirin family
EI070_05280	COG2964	Protein conserved in bacteria
EI070_05295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EI070_05300	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI070_05305	COG4605	iron ion homeostasis
EI070_05310	COG4604	ABC transporter, ATP-binding protein
EI070_05315	COG4607	ABC-type enterochelin transport system periplasmic component
EI070_05320	COG4774	siderophore transport
EI070_05330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EI070_05335	COG1021	2,3-dihydroxybenzoate-AMP ligase
EI070_05340	COG1535	isochorismatase
EI070_05340	COG3433	isochorismatase activity
EI070_05355	COG1132	(ABC) transporter
EI070_05365	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EI070_05375	COG1169	isochorismate synthase
EI070_05390	COG3739	integral membrane protein
EI070_05425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EI070_05455	COG0308	aminopeptidase N
EI070_05460	COG0512	Glutamine amidotransferase of anthranilate synthase
EI070_05780	COG0582	viral genome integration into host DNA
EI070_05790	COG3104	oligopeptide transport
EI070_05805	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EI070_05840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EI070_05845	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EI070_05850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI070_05870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EI070_05875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EI070_05880	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EI070_05895	COG1960	acyl-CoA dehydrogenase activity
EI070_05900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EI070_05905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI070_05915	COG2223	nitrite transmembrane transporter activity
EI070_05925	COG0024	Methionine aminopeptidase
EI070_05930	COG0052	Belongs to the universal ribosomal protein uS2 family
EI070_05945	COG2207	Transcriptional regulator
EI070_05970	COG2951	lytic endotransglycosylase activity
EI070_05975	COG0772	Belongs to the SEDS family
EI070_05990	COG0842	Transport permease protein
EI070_05995	COG1131	(ABC) transporter
EI070_06030	COG1538	Outer membrane efflux protein
EI070_06040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI070_06055	COG4215	(ABC) transporter
EI070_06060	COG4160	amino acid transport
EI070_06065	COG4598	ABC transporter
EI070_06075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EI070_06085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI070_06100	COG1720	tRNA m6t6A37 methyltransferase activity
EI070_06120	COG0745	RESPONSE REGULATOR receiver
EI070_06125	COG0642	Histidine kinase
EI070_06135	COG0494	nUDIX hydrolase
EI070_06145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EI070_06150	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EI070_06155	COG3139	Protein of unknown function (DUF1315)
EI070_06160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EI070_06170	COG1301	dicarboxylic acid transport
EI070_06175	COG1960	acyl-CoA dehydrogenase activity
EI070_06180	COG2819	hydrolase of the alpha beta superfamily
EI070_06190	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EI070_06200	COG2195	Cleaves the N-terminal amino acid of tripeptides
EI070_06205	COG1234	tRNA 3'-trailer cleavage
EI070_06235	COG2363	Small membrane protein
EI070_06255	COG0513	Belongs to the DEAD box helicase family
EI070_06265	COG0778	Nitroreductase
EI070_06295	COG1286	toxin biosynthetic process
EI070_06320	COG4783	chaperone-mediated protein folding
EI070_06325	COG1610	YqeY-like protein
EI070_06330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EI070_06425	COG3111	PFAM Bacterial OB fold (BOF) protein
EI070_06450	COG3243	poly(R)-hydroxyalkanoic acid synthase
EI070_06455	COG0786	glutamate:sodium symporter activity
EI070_06465	COG2186	Transcriptional regulator
EI070_06515	COG0477	Major facilitator Superfamily
EI070_06545	COG2985	domain, Protein
EI070_06555	COG2995	paraquat-inducible protein a
EI070_06560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EI070_06560	COG3008	intermembrane lipid transfer
EI070_06570	COG1794	racemase activity, acting on amino acids and derivatives
EI070_06590	COG3316	Transposase and inactivated derivatives
EI070_06605	COG3316	Transposase and inactivated derivatives
EI070_06660	COG0482	sulfurtransferase activity
EI070_06680	COG3173	Aminoglycoside phosphotransferase
EI070_06690	COG2433	Pfam Transposase IS66
EI070_06715	COG3316	Transposase and inactivated derivatives
EI070_06735	COG1301	dicarboxylic acid transport
EI070_06745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI070_06750	COG2011	ABC-type metal ion transport system permease component
EI070_06755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EI070_06760	COG1464	Belongs to the NlpA lipoprotein family
EI070_06765	COG0151	Belongs to the GarS family
EI070_06770	COG0138	bifunctional purine biosynthesis protein purh
EI070_06775	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EI070_06805	COG2308	Evidence 4 Homologs of previously reported genes of
EI070_06815	COG1305	Transglutaminase-like
EI070_06825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EI070_06830	COG0305	Participates in initiation and elongation during chromosome replication
EI070_06855	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EI070_06865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EI070_06870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EI070_06895	COG1649	PFAM Uncharacterised BCR, COG1649
EI070_06895	COG0726	polysaccharide deacetylase
EI070_06900	COG1215	transferase activity, transferring glycosyl groups
EI070_06905	COG3658	cytochrome
EI070_06915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EI070_06935	COG0583	DNA-binding transcription factor activity
EI070_06955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EI070_06960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EI070_06975	COG1960	acyl-CoA dehydrogenase activity
EI070_06980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EI070_06985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI070_07010	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EI070_07015	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EI070_07025	COG2205	protein histidine kinase activity
EI070_07030	COG0745	RESPONSE REGULATOR receiver
EI070_07035	COG0174	glutamine synthetase
EI070_07055	COG0729	surface antigen
EI070_07085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI070_07090	COG2814	Major facilitator Superfamily
EI070_07105	COG0583	DNA-binding transcription factor activity
EI070_07120	COG1187	pseudouridine synthase activity
EI070_07140	COG0802	atpase or kinase
EI070_07145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EI070_07155	COG1923	regulation of RNA biosynthetic process
EI070_07160	COG0697	spore germination
EI070_07175	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI070_07190	COG0519	Catalyzes the synthesis of GMP from XMP
EI070_07190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EI070_07195	COG4302	ethanolamine ammonia-lyase activity
EI070_07200	COG4303	Ethanolamine ammonia lyase large subunit
EI070_07205	COG0531	amino acid
EI070_07225	COG1454	alcohol dehydrogenase
EI070_07230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EI070_07240	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EI070_07260	COG0308	aminopeptidase N
EI070_07270	COG4221	oxidoreductase activity
EI070_07280	COG1605	Chorismate mutase
EI070_07300	COG1309	transcriptional regulator
EI070_07310	COG0668	transmembrane transport
EI070_07345	COG4773	Receptor
EI070_07365	COG0488	(ABC) transporter
EI070_07370	COG0589	response to stress
EI070_07385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EI070_07395	COG3135	benzoate transporter
EI070_07400	COG1522	sequence-specific DNA binding
EI070_07415	COG0583	DNA-binding transcription factor activity
EI070_07425	COG0183	Belongs to the thiolase family
EI070_07455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EI070_07465	COG0824	Thioesterase
EI070_07470	COG1454	alcohol dehydrogenase
EI070_07480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EI070_07500	COG0069	glutamate synthase activity
EI070_07775	COG1598	PFAM Uncharacterised protein family UPF0150
EI070_07810	COG0739	heme binding
EI070_07905	COG2814	Major facilitator Superfamily
EI070_07920	COG0511	ligase activity, forming carbon-carbon bonds
EI070_07940	COG1116	anion transmembrane transporter activity
EI070_07940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EI070_07945	COG0745	RESPONSE REGULATOR receiver
EI070_07955	COG2146	nitrite reductase [NAD(P)H] activity
EI070_07955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI070_07960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI070_07965	COG0243	molybdopterin cofactor binding
EI070_07975	COG0243	molybdopterin cofactor binding
EI070_07980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EI070_07995	COG0315	cyclic pyranopterin monophosphate synthase activity
EI070_07995	COG0521	Mo-molybdopterin cofactor biosynthetic process
EI070_08000	COG0303	'Molybdopterin
EI070_08010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI070_08015	COG0697	spore germination
EI070_08035	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EI070_08040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EI070_08115	COG2204	response regulator
EI070_08120	COG3852	Histidine kinase
EI070_08145	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EI070_08150	COG0575	Belongs to the CDS family
EI070_08185	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI070_08200	COG2137	regulation of response to DNA damage stimulus
EI070_08210	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EI070_08215	COG1011	Hydrolase
EI070_08240	COG1522	sequence-specific DNA binding
EI070_08250	COG1113	amino acid transport
EI070_08265	COG0659	secondary active sulfate transmembrane transporter activity
EI070_08270	COG2135	peptidase activity
EI070_08285	COG3300	MHYT domain
EI070_08285	COG5001	Diguanylate cyclase
EI070_08305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EI070_08305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EI070_08305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EI070_08310	COG1105	Belongs to the carbohydrate kinase PfkB family
EI070_08315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI070_08315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EI070_08345	COG0024	Methionine aminopeptidase
EI070_08350	COG0583	DNA-binding transcription factor activity
EI070_08360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EI070_08365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EI070_08370	COG0516	GMP reductase activity
EI070_08370	COG0517	IMP dehydrogenase activity
EI070_08395	COG0552	protein localization to endoplasmic reticulum
EI070_08405	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EI070_08420	COG4890	Cyd operon protein YbgT
EI070_08425	COG1294	oxidase, subunit
EI070_08440	COG1585	Membrane protein implicated in regulation of membrane protease activity
EI070_08450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EI070_08455	COG4774	siderophore transport
EI070_08470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EI070_08475	COG0569	domain protein
EI070_08480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EI070_08510	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EI070_08515	COG0542	response to heat
EI070_08525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EI070_08540	COG1902	pentaerythritol trinitrate reductase activity
EI070_08540	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI070_08585	COG2323	membrane
EI070_08590	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EI070_08600	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EI070_08605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EI070_08610	COG0183	Belongs to the thiolase family
EI070_08615	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EI070_08620	COG0596	Alpha beta hydrolase
EI070_08625	COG2271	Major facilitator Superfamily
EI070_08630	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EI070_08635	COG3485	protocatechuate 3,4-dioxygenase
EI070_08640	COG3485	protocatechuate 3,4-dioxygenase
EI070_08645	COG0710	3-dehydroquinate dehydratase activity
EI070_08650	COG3420	alginic acid biosynthetic process
EI070_08655	COG3659	wide pore channel activity
EI070_08660	COG4993	Dehydrogenase
EI070_08670	COG2391	methyltransferase activity
EI070_08685	COG1414	Transcriptional regulator
EI070_08690	COG0583	DNA-binding transcription factor activity
EI070_08695	COG1960	acyl-CoA dehydrogenase activity
EI070_08720	COG2814	Major facilitator Superfamily
EI070_08730	COG0154	amidase activity
EI070_08750	COG4638	Rieske (2fe-2S)
EI070_08760	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_08770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI070_08780	COG3733	amine oxidase
EI070_08790	COG1012	belongs to the aldehyde dehydrogenase family
EI070_08800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EI070_08805	COG0183	Belongs to the thiolase family
EI070_08810	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EI070_08815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EI070_08825	COG4829	muconolactone delta-isomerase
EI070_08830	COG4948	Mandelate Racemase Muconate Lactonizing
EI070_08835	COG0583	DNA-binding transcription factor activity
EI070_08845	COG2186	Transcriptional regulator
EI070_08865	COG1012	belongs to the aldehyde dehydrogenase family
EI070_08885	COG1960	acyl-CoA dehydrogenase activity
EI070_08895	COG3829	transcription factor binding
EI070_08905	COG3162	membrane
EI070_08920	COG1012	belongs to the aldehyde dehydrogenase family
EI070_08935	COG0753	catalase activity
EI070_08960	COG1846	Transcriptional regulator
EI070_08965	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI070_08965	COG1902	pentaerythritol trinitrate reductase activity
EI070_08975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EI070_09005	COG1309	transcriptional regulator
EI070_09015	COG1335	isochorismatase
EI070_09020	COG0583	DNA-binding transcription factor activity
EI070_09030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EI070_09030	COG0475	glutathione-regulated potassium exporter activity
EI070_09040	COG1473	amidohydrolase
EI070_09055	COG2831	hemolysin activation secretion protein
EI070_09060	COG3210	domain, Protein
EI070_09115	COG0583	DNA-binding transcription factor activity
EI070_09140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EI070_09145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EI070_09165	COG1566	PFAM secretion protein HlyD family protein
EI070_09180	COG1012	belongs to the aldehyde dehydrogenase family
EI070_09185	COG0129	dihydroxy-acid dehydratase activity
EI070_09195	COG0583	DNA-binding transcription factor activity
EI070_09200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI070_09210	COG2084	Dehydrogenase
EI070_09215	COG2207	Transcriptional regulator
EI070_09230	COG1064	alcohol dehydrogenase
EI070_09245	COG1120	ATPase activity
EI070_09265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EI070_09385	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EI070_09440	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_09455	COG2207	Transcriptional regulator
EI070_09465	COG2205	protein histidine kinase activity
EI070_09470	COG0745	RESPONSE REGULATOR receiver
EI070_09475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI070_09480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI070_09485	COG1538	Outer membrane efflux protein
EI070_09495	COG2072	flavoprotein involved in K transport
EI070_09515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EI070_09535	COG3539	Fimbrial protein
EI070_09565	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EI070_09575	COG0753	catalase activity
EI070_09590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EI070_09655	COG1535	isochorismatase
EI070_09655	COG3433	isochorismatase activity
EI070_09660	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_09665	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EI070_09670	COG4149	molybdate abc transporter
EI070_09675	COG0725	ABC transporter, periplasmic molybdate-binding protein
EI070_09685	COG4638	Rieske (2fe-2S)
EI070_09690	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EI070_09695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EI070_09695	COG0543	2 iron, 2 sulfur cluster binding
EI070_09710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI070_09720	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_09725	COG0412	Dienelactone hydrolase
EI070_09735	COG2207	Transcriptional regulator
EI070_09745	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_09750	COG2610	gluconate transmembrane transporter activity
EI070_09760	COG0583	DNA-binding transcription factor activity
EI070_09770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EI070_09775	COG2031	fatty acid transporter
EI070_09780	COG0183	Belongs to the thiolase family
EI070_09785	COG0583	DNA-binding transcription factor activity
EI070_09790	COG0583	DNA-binding transcription factor activity
EI070_09805	COG1027	Aspartate ammonia-lyase
EI070_09815	COG0477	Major facilitator Superfamily
EI070_09835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EI070_09840	COG4521	taurine ABC transporter
EI070_09865	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EI070_09870	COG1733	regulation of RNA biosynthetic process
EI070_09875	COG3708	Transcriptional regulator
EI070_09875	COG2207	Transcriptional regulator
EI070_09890	COG0730	response to heat
EI070_09900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI070_09900	COG3453	Protein conserved in bacteria
EI070_09910	COG3781	membrane
EI070_09915	COG1063	alcohol dehydrogenase
EI070_09925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI070_09930	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI070_09935	COG0022	dehydrogenase e1 component
EI070_09940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EI070_09945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EI070_09960	COG3706	GGDEF domain
EI070_09975	COG0133	tryptophan synthase activity
EI070_09985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EI070_10020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EI070_10045	COG2226	methyltransferase
EI070_10100	COG0842	Transport permease protein
EI070_10105	COG0842	Transport permease protein
EI070_10110	COG1131	(ABC) transporter
EI070_10125	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI070_10130	COG4773	Receptor
EI070_10150	COG0730	response to heat
EI070_10155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EI070_10175	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EI070_10235	COG4264	IucA IucC family
EI070_10240	COG4264	IucA IucC family
EI070_10260	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EI070_10275	COG1960	acyl-CoA dehydrogenase activity
EI070_10280	COG1960	acyl-CoA dehydrogenase activity
EI070_10285	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI070_10290	COG2207	Transcriptional regulator
EI070_10295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EI070_10300	COG0776	regulation of translation
EI070_10325	COG0822	iron-sulfur transferase activity
EI070_10330	COG0316	Belongs to the HesB IscA family
EI070_10360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EI070_10380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EI070_10385	COG0702	epimerase
EI070_10420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI070_10430	COG0339	signal peptide processing
EI070_10480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EI070_10485	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EI070_10515	COG0776	regulation of translation
EI070_10535	COG0590	tRNA wobble adenosine to inosine editing
EI070_10565	COG2165	general secretion pathway protein
EI070_10580	COG0084	hydrolase, TatD family'
EI070_10600	COG1663	tetraacyldisaccharide 4'-kinase activity
EI070_10605	COG1132	(ABC) transporter
EI070_10615	COG0811	peptide transport
EI070_10620	COG1475	DNA binding
EI070_10625	COG1192	Involved in chromosome partitioning
EI070_10635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EI070_10650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EI070_10655	COG0191	fructose-bisphosphate aldolase activity
EI070_10675	COG0424	maF-like protein
EI070_10680	COG2850	peptidyl-arginine hydroxylation
EI070_10690	COG0640	Transcriptional regulator
EI070_10700	COG3619	membrane
EI070_10705	COG3122	Protein conserved in bacteria
EI070_10710	COG1132	(ABC) transporter
EI070_10730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EI070_10735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EI070_10745	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EI070_10745	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EI070_10745	COG0506	proline dehydrogenase activity
EI070_10750	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EI070_10765	COG3698	Phosphodiester glycosidase
EI070_10780	COG1765	OsmC-like protein
EI070_10795	COG2353	YceI-like domain
EI070_10805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EI070_10850	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EI070_10850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EI070_10875	COG3539	Fimbrial protein
EI070_10880	COG3121	Chaperone
EI070_10910	COG0697	spore germination
EI070_10920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EI070_10930	COG0583	DNA-binding transcription factor activity
EI070_10950	COG1309	transcriptional regulator
EI070_10965	COG1522	sequence-specific DNA binding
EI070_10975	COG1126	abc transporter atp-binding protein
EI070_10980	COG0765	amino acid transport
EI070_10985	COG0765	amino acid transport
EI070_11015	COG1464	Belongs to the NlpA lipoprotein family
EI070_11025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EI070_11030	COG2011	ABC-type metal ion transport system permease component
EI070_11035	COG0012	GTP binding
EI070_11060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EI070_11100	COG0386	Belongs to the glutathione peroxidase family
EI070_11110	COG0436	Aminotransferase
EI070_11150	COG3634	alkyl hydroperoxide reductase activity
EI070_11165	COG0583	DNA-binding transcription factor activity
EI070_11170	COG0798	PFAM Bile acid sodium symporter
EI070_11175	COG0640	Transcriptional regulator
EI070_11190	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EI070_11200	COG0583	DNA-binding transcription factor activity
EI070_11215	COG1953	Uracil, thiamine, allantoin
EI070_11225	COG2175	clavaminate synthase activity
EI070_11230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EI070_11235	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EI070_11240	COG4521	taurine ABC transporter
EI070_11250	COG0477	Major facilitator Superfamily
EI070_11275	COG1271	oxidase subunit
EI070_11280	COG1294	oxidase, subunit
EI070_11290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI070_11310	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EI070_11330	COG3052	prosthetic group binding
EI070_11335	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EI070_11345	COG2814	Major facilitator Superfamily
EI070_11365	COG1346	cytolysis
EI070_11375	COG0583	DNA-binding transcription factor activity
EI070_11380	COG0625	glutathione transferase activity
EI070_11385	COG0625	glutathione transferase activity
EI070_11390	COG0583	DNA-binding transcription factor activity
EI070_11405	COG1045	serine acetyltransferase
EI070_11410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI070_11415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EI070_11425	COG1280	lysine exporter protein (LysE YggA)
EI070_11440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EI070_11445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EI070_11450	COG1126	abc transporter atp-binding protein
EI070_11455	COG0765	amino acid transport
EI070_11460	COG0765	amino acid transport
EI070_11480	COG0784	Response regulator, receiver
EI070_11480	COG2205	protein histidine kinase activity
EI070_11500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EI070_11520	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_11565	COG0583	DNA-binding transcription factor activity
EI070_11585	COG0318	PFAM AMP-dependent synthetase and ligase
EI070_11590	COG1309	transcriptional regulator
EI070_11595	COG1960	acyl-CoA dehydrogenase activity
EI070_11600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EI070_11605	COG1024	Enoyl-CoA hydratase
EI070_11620	COG0583	DNA-binding transcription factor activity
EI070_11635	COG1960	acyl-CoA dehydrogenase activity
EI070_11645	COG2814	Major facilitator Superfamily
EI070_11655	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EI070_11660	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EI070_11665	COG2814	Major facilitator Superfamily
EI070_11670	COG1960	acyl-CoA dehydrogenase activity
EI070_11675	COG1024	Enoyl-CoA hydratase
EI070_11680	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_11685	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI070_11690	COG0183	Belongs to the thiolase family
EI070_11700	COG2814	Major facilitator Superfamily
EI070_11710	COG1024	Enoyl-CoA hydratase
EI070_11725	COG1960	acyl-CoA dehydrogenase activity
EI070_11730	COG2814	Major facilitator Superfamily
EI070_11735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI070_11740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EI070_11755	COG3842	ATPase activity
EI070_11760	COG1840	ABC-type Fe3 transport system, periplasmic component
EI070_11795	COG0038	chloride channel
EI070_11800	COG4770	biotin carboxylase activity
EI070_11820	COG1914	H( )-stimulated, divalent metal cation uptake system
EI070_11825	COG0583	DNA-binding transcription factor activity
EI070_11840	COG3209	COG3209 Rhs family protein
EI070_11845	COG3501	Rhs element vgr protein
EI070_11880	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI070_11900	COG2814	Major facilitator Superfamily
EI070_11915	COG1560	Kdo2-lipid A biosynthetic process
EI070_11925	COG5006	permease, DMT superfamily
EI070_11930	COG1522	sequence-specific DNA binding
EI070_11945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EI070_11985	COG1538	Outer membrane efflux protein
EI070_11990	COG1137	ATPase activity
EI070_11995	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EI070_12005	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EI070_12010	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EI070_12010	COG0517	IMP dehydrogenase activity
EI070_12045	COG1733	regulation of RNA biosynthetic process
EI070_12050	COG2814	Major facilitator Superfamily
EI070_12090	COG1278	Cold shock
EI070_12095	COG1280	lysine exporter protein (LysE YggA)
EI070_12130	COG1570	exodeoxyribonuclease VII activity
EI070_12185	COG0583	DNA-binding transcription factor activity
EI070_12190	COG4638	Rieske (2fe-2S)
EI070_12195	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EI070_12200	COG0543	2 iron, 2 sulfur cluster binding
EI070_12200	COG0633	Ferredoxin
EI070_12205	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_12210	COG3135	benzoate transporter
EI070_12215	COG2814	Major facilitator Superfamily
EI070_12230	COG1643	Atp-dependent helicase
EI070_12235	COG0450	alkyl hydroperoxide reductase
EI070_12245	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EI070_12255	COG3634	alkyl hydroperoxide reductase activity
EI070_12275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EI070_12280	COG0625	glutathione transferase activity
EI070_12290	COG2885	chlorophyll binding
EI070_12345	COG1765	OsmC-like protein
EI070_12360	COG0667	Aldo Keto reductase
EI070_12375	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EI070_12385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EI070_12405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EI070_12415	COG3038	cytochrome b561
EI070_12420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EI070_12425	COG2252	PERMEase
EI070_12435	COG2072	flavoprotein involved in K transport
EI070_12455	COG3316	Transposase and inactivated derivatives
EI070_12460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EI070_12470	COG3316	Transposase and inactivated derivatives
EI070_12495	COG3316	Transposase and inactivated derivatives
EI070_12500	COG1113	amino acid transport
EI070_12520	COG1012	belongs to the aldehyde dehydrogenase family
EI070_12540	COG0531	amino acid
EI070_12550	COG1113	amino acid transport
EI070_12595	COG3209	COG3209 Rhs family protein
EI070_12600	COG3501	Rhs element vgr protein
EI070_12620	COG4269	membrane
EI070_12635	COG1902	pentaerythritol trinitrate reductase activity
EI070_12635	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI070_12645	COG5001	Diguanylate cyclase
EI070_12645	COG4251	negative regulation of phosphorylation
EI070_12645	COG3706	GGDEF domain
EI070_12645	COG2203	Gaf domain
EI070_12655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EI070_12675	COG4172	Belongs to the ABC transporter superfamily
EI070_12680	COG4239	(ABC) transporter, permease
EI070_12685	COG4174	ABC transporter (Permease)
EI070_12695	COG0741	lytic transglycosylase activity
EI070_12695	COG1388	LysM domain
EI070_12695	COG0741	lytic transglycosylase activity
EI070_12695	COG1388	LysM domain
EI070_12700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EI070_12740	COG0583	DNA-binding transcription factor activity
EI070_12745	COG1279	arginine transmembrane transporter activity
EI070_12765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EI070_12770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EI070_12775	COG0006	proline dipeptidase activity
EI070_12810	COG2194	sulfuric ester hydrolase activity
EI070_12855	COG0739	heme binding
EI070_13180	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EI070_13205	COG3384	dioxygenase
EI070_13215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EI070_13220	COG2878	Part of a membrane complex involved in electron transport
EI070_13225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EI070_13250	COG0768	penicillin binding
EI070_13255	COG0742	ribosomal rna small subunit methyltransferase
EI070_13270	COG0830	nickel cation binding
EI070_13280	COG0804	urea catabolic process
EI070_13320	COG1253	flavin adenine dinucleotide binding
EI070_13330	COG2851	Citrate transporter
EI070_13380	COG1773	rubredoxin
EI070_13385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI070_13395	COG0583	DNA-binding transcription factor activity
EI070_13420	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EI070_13425	COG4181	ATPase activity
EI070_13470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EI070_13490	COG0306	phosphate transporter
EI070_13500	COG3958	Transketolase
EI070_13505	COG3959	Transketolase, thiamine diphosphate binding domain
EI070_13510	COG2271	Major facilitator Superfamily
EI070_13515	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_13520	COG0583	DNA-binding transcription factor activity
EI070_13540	COG2223	nitrite transmembrane transporter activity
EI070_13545	COG2207	Transcriptional regulator
EI070_13550	COG2066	Belongs to the glutaminase family
EI070_13555	COG0242	peptide deformylase activity
EI070_13560	COG0477	Major facilitator Superfamily
EI070_13570	COG0028	Belongs to the TPP enzyme family
EI070_13585	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_13590	COG2267	carboxylic ester hydrolase activity
EI070_13600	COG2271	Major facilitator Superfamily
EI070_13605	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI070_13615	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_13635	COG1414	Transcriptional regulator
EI070_13650	COG1024	Enoyl-CoA hydratase
EI070_13660	COG1215	transferase activity, transferring glycosyl groups
EI070_13665	COG1649	PFAM Uncharacterised BCR, COG1649
EI070_13665	COG0726	polysaccharide deacetylase
EI070_13675	COG4681	YaeQ
EI070_13685	COG0523	cobalamin synthesis protein
EI070_13695	COG1607	acyl-coa hydrolase
EI070_13705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EI070_13710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EI070_13715	COG1309	transcriptional regulator
EI070_13740	COG2040	homocysteine
EI070_13745	COG0531	amino acid
EI070_13800	COG1595	DNA-templated transcription, initiation
EI070_13810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EI070_13815	COG0477	Major facilitator Superfamily
EI070_13885	COG0629	single-stranded DNA binding
EI070_13930	COG0582	viral genome integration into host DNA
EI070_13950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EI070_14035	COG0592	DNA-directed DNA polymerase activity
EI070_14075	COG2026	Addiction module toxin, RelE StbE family
EI070_14225	COG3755	Protein conserved in bacteria
EI070_14270	COG1484	DNA-dependent DNA replication
EI070_14360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EI070_14425	COG0405	Gamma-glutamyltransferase
EI070_14430	COG2814	Major facilitator Superfamily
EI070_14440	COG2050	protein possibly involved in aromatic compounds catabolism
EI070_14455	COG1090	epimerase
EI070_14475	COG0420	3'-5' exonuclease activity
EI070_14500	COG0735	belongs to the Fur family
EI070_14505	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EI070_14530	COG0121	glutamine amidotransferase
EI070_14545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EI070_14555	COG0210	DNA helicase
EI070_14560	COG2885	chlorophyll binding
EI070_14565	COG0204	Acyl-transferase
EI070_14580	COG2894	cell division
EI070_14605	COG1280	lysine exporter protein (LysE YggA)
EI070_14610	COG1674	ftsk spoiiie
EI070_14610	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EI070_14615	COG0492	ferredoxin-NADP+ reductase activity
EI070_14620	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EI070_14630	COG0456	acetyltransferase
EI070_14690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EI070_14690	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EI070_14710	COG1012	belongs to the aldehyde dehydrogenase family
EI070_14730	COG0473	3-isopropylmalate dehydrogenase activity
EI070_14735	COG0583	DNA-binding transcription factor activity
EI070_14755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EI070_14780	COG0564	pseudouridine synthase activity
EI070_14790	COG0358	DNA primase activity
EI070_14805	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EI070_14835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EI070_14865	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EI070_14875	COG0352	thiamine-phosphate diphosphorylase activity
EI070_14875	COG0351	phosphomethylpyrimidine kinase
EI070_14875	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EI070_14880	COG1652	LysM domain
EI070_14905	COG1399	metal-binding, possibly nucleic acid-binding protein
EI070_14910	COG3101	peptidyl-lysine hydroxylation
EI070_14915	COG0009	L-threonylcarbamoyladenylate synthase
EI070_14920	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EI070_14925	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EI070_14940	COG4106	trans-aconitate 2-methyltransferase activity
EI070_14955	COG2226	methyltransferase
EI070_14955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EI070_14955	COG0596	Alpha beta hydrolase
EI070_14960	COG1877	trehalose-phosphatase activity
EI070_14965	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EI070_14970	COG2223	nitrite transmembrane transporter activity
EI070_14990	COG1196	nuclear chromosome segregation
EI070_15000	COG0730	response to heat
EI070_15015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EI070_15025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EI070_15085	COG0489	protein tyrosine kinase activity
EI070_15095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI070_15095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI070_15125	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EI070_15130	COG2081	HI0933 family
EI070_15140	COG0668	transmembrane transport
EI070_15160	COG0583	DNA-binding transcription factor activity
EI070_15180	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EI070_15185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EI070_15215	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EI070_15250	COG2205	protein histidine kinase activity
EI070_15255	COG0745	RESPONSE REGULATOR receiver
EI070_15275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EI070_15285	COG2205	protein histidine kinase activity
EI070_15355	COG4993	Dehydrogenase
EI070_15375	COG0384	phenazine biosynthesis protein PhzF
EI070_15405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI070_15410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EI070_15420	COG0583	DNA-binding transcription factor activity
EI070_15440	COG1473	amidohydrolase
EI070_15450	COG0583	DNA-binding transcription factor activity
EI070_15470	COG0583	DNA-binding transcription factor activity
EI070_15475	COG1053	succinate dehydrogenase
EI070_15485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EI070_15490	COG2814	Major facilitator Superfamily
EI070_15495	COG1960	acyl-CoA dehydrogenase activity
EI070_15500	COG0583	DNA-binding transcription factor activity
EI070_15505	COG1063	alcohol dehydrogenase
EI070_15535	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EI070_15540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EI070_15545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EI070_15560	COG3667	copper resistance
EI070_15565	COG2132	Multicopper oxidase
EI070_15575	COG0561	phosphatase activity
EI070_15580	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EI070_15605	COG1214	PFAM Peptidase M22, glycoprotease
EI070_15665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EI070_15675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EI070_15680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EI070_15685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EI070_15745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EI070_15755	COG1846	Transcriptional regulator
EI070_15760	COG1764	response to oxidative stress
EI070_15800	COG0037	tRNA processing
EI070_15810	COG0248	Ppx GppA phosphatase
EI070_15840	COG0072	phenylalanine-tRNA ligase activity
EI070_15865	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EI070_15880	COG1238	metal cluster binding
EI070_15885	COG0625	glutathione transferase activity
EI070_15905	COG0318	PFAM AMP-dependent synthetase and ligase
EI070_15910	COG3028	Belongs to the UPF0307 family
EI070_15915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EI070_15935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EI070_15940	COG0617	tRNA 3'-terminal CCA addition
EI070_15945	COG1555	photosystem II stabilization
EI070_15950	COG3956	TIGRFAM MazG family protein
EI070_15960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EI070_15980	COG5002	protein histidine kinase activity
EI070_15980	COG2205	protein histidine kinase activity
EI070_15980	COG0784	Response regulator, receiver
EI070_15985	COG1024	Enoyl-CoA hydratase
EI070_15990	COG2084	Dehydrogenase
EI070_15995	COG3622	Belongs to the hyi family
EI070_16010	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EI070_16015	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EI070_16020	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EI070_16025	COG0697	spore germination
EI070_16035	COG2814	Major facilitator Superfamily
EI070_16040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EI070_16050	COG0583	DNA-binding transcription factor activity
EI070_16060	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EI070_16075	COG0084	hydrolase, TatD family'
EI070_16090	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EI070_16125	COG0440	acetolactate synthase activity
EI070_16130	COG0028	Belongs to the TPP enzyme family
EI070_16155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI070_16160	COG1136	(ABC) transporter
EI070_16160	COG0577	efflux transmembrane transporter activity
EI070_16165	COG1538	Outer membrane efflux protein
EI070_16180	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EI070_16185	COG1162	GTPase activity
EI070_16195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EI070_16215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EI070_16220	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_16260	COG2986	histidine ammonia-lyase
EI070_16275	COG0318	PFAM AMP-dependent synthetase and ligase
EI070_16285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI070_16290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI070_16330	COG1426	Protein conserved in bacteria
EI070_16365	COG0793	Belongs to the peptidase S41A family
EI070_16380	COG2267	carboxylic ester hydrolase activity
EI070_16390	COG1012	belongs to the aldehyde dehydrogenase family
EI070_16395	COG3265	gluconokinase activity
EI070_16405	COG0800	Aldolase
EI070_16415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EI070_16420	COG0280	phosphate acetyltransferase
EI070_16420	COG0857	belongs to the CobB CobQ family
EI070_16425	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EI070_16425	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EI070_16445	COG0740	serine-type endopeptidase activity
EI070_16455	COG4774	siderophore transport
EI070_16465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EI070_16475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EI070_16475	COG2813	Specifically methylates the guanine in position
EI070_16575	COG0788	formyltetrahydrofolate deformylase activity
EI070_16590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EI070_16595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EI070_16600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EI070_16600	COG4651	solute:proton antiporter activity
EI070_16620	COG0724	RNA recognition motif
EI070_16625	COG0210	DNA helicase
EI070_16650	COG1733	regulation of RNA biosynthetic process
EI070_16670	COG1280	lysine exporter protein (LysE YggA)
EI070_16675	COG1560	Kdo2-lipid A biosynthetic process
EI070_16685	COG1301	dicarboxylic acid transport
EI070_16740	COG0473	3-isopropylmalate dehydrogenase activity
EI070_16805	COG0583	DNA-binding transcription factor activity
EI070_16815	COG0625	glutathione transferase activity
EI070_16820	COG2378	regulation of single-species biofilm formation
EI070_16825	COG0546	phosphoglycolate phosphatase activity
EI070_16840	COG1530	ribonuclease E activity
EI070_16860	COG0583	DNA-binding transcription factor activity
EI070_16865	COG4221	oxidoreductase activity
EI070_16870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EI070_16880	COG0534	Mate efflux family protein
EI070_16895	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EI070_16935	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EI070_16940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI070_16955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EI070_16965	COG0644	oxidoreductase
EI070_16965	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EI070_16970	COG0425	Belongs to the sulfur carrier protein TusA family
EI070_16975	COG4535	Mg2 and Co2 transporter CorC
EI070_16985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI070_17005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EI070_17010	COG0475	glutathione-regulated potassium exporter activity
EI070_17010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EI070_17015	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EI070_17025	COG0484	heat shock protein binding
EI070_17030	COG0789	Transcriptional regulator
EI070_17035	COG0598	Magnesium transport protein CorA
EI070_17055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EI070_17060	COG1074	ATP-dependent DNA helicase activity
EI070_17065	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EI070_17085	COG2226	methyltransferase
EI070_17100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EI070_17105	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EI070_17120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EI070_17120	COG2111	Na H antiporter
EI070_17125	COG1006	Multisubunit Na H antiporter MnhC subunit
EI070_17130	COG0651	ATP synthesis coupled electron transport
EI070_17140	COG2212	antiporter activity
EI070_17160	COG0195	Participates in both transcription termination and antitermination
EI070_17210	COG0237	dephospho-CoA kinase activity
EI070_17220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI070_17235	COG0497	DNA recombination
EI070_17245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EI070_17275	COG2169	Transcriptional regulator
EI070_17275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EI070_17280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EI070_17350	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EI070_17380	COG0326	Molecular chaperone. Has ATPase activity
EI070_17395	COG2056	Na+-H+ antiporter family
EI070_17400	COG0596	Alpha beta hydrolase
EI070_17495	COG0546	phosphoglycolate phosphatase activity
EI070_17500	COG1716	ATPase activity
EI070_17545	COG0181	hydroxymethylbilane synthase activity
EI070_17555	COG3275	phosphorelay sensor kinase activity
EI070_17575	COG1538	Outer membrane efflux protein
EI070_17580	COG0697	spore germination
EI070_17605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EI070_17610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EI070_17615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI070_17620	COG0772	Belongs to the SEDS family
EI070_17645	COG4974	Belongs to the 'phage' integrase family
EI070_17650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EI070_17660	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EI070_17670	COG2197	response regulator
EI070_17685	COG0793	Belongs to the peptidase S41A family
EI070_17690	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EI070_17695	COG0795	lipopolysaccharide-transporting ATPase activity
EI070_17735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EI070_17735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EI070_17745	COG0004	ammonium transporteR
EI070_17750	COG0347	Belongs to the P(II) protein family
EI070_17760	COG0606	chelatase, subunit chli
EI070_17815	COG0659	secondary active sulfate transmembrane transporter activity
EI070_17820	COG0589	response to stress
EI070_17865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EI070_17965	COG0659	secondary active sulfate transmembrane transporter activity
EI070_17970	COG0589	response to stress
EI070_18010	COG0606	chelatase, subunit chli
EI070_18015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI070_18025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EI070_18040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EI070_18055	COG0318	PFAM AMP-dependent synthetase and ligase
EI070_18065	COG0477	Major facilitator Superfamily
EI070_18070	COG2860	membrane
EI070_18080	COG1253	flavin adenine dinucleotide binding
EI070_18100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EI070_18135	COG0655	NAD(P)H dehydrogenase (quinone) activity
EI070_18145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EI070_18180	COG1309	transcriptional regulator
EI070_18215	COG0758	DNA mediated transformation
EI070_18225	COG0697	spore germination
EI070_18230	COG1309	transcriptional regulator
EI070_18245	COG0386	Belongs to the glutathione peroxidase family
EI070_18310	COG1121	(ABC) transporter
EI070_18315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EI070_18320	COG1280	lysine exporter protein (LysE YggA)
EI070_18325	COG2837	iron assimilation
EI070_18335	COG0281	malic enzyme
EI070_18380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EI070_18380	COG0519	Catalyzes the synthesis of GMP from XMP
EI070_18385	COG4399	Belongs to the UPF0754 family
EI070_18390	COG2259	Doxx family
EI070_18395	COG0586	Pfam SNARE associated Golgi protein
EI070_18410	COG1192	Involved in chromosome partitioning
EI070_18420	COG0271	Belongs to the BolA IbaG family
EI070_18440	COG2267	carboxylic ester hydrolase activity
EI070_18460	COG3321	synthase
EI070_18460	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EI070_18460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI070_18460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EI070_18465	COG1960	acyl-CoA dehydrogenase activity
EI070_18475	COG2197	response regulator
EI070_18485	COG3916	Acyl-homoserine-lactone synthase
EI070_18490	COG0477	Major facilitator Superfamily
EI070_18495	COG1024	Enoyl-CoA hydratase
EI070_18500	COG1024	Enoyl-CoA hydratase
EI070_18505	COG1960	acyl-CoA dehydrogenase activity
EI070_18510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EI070_18530	COG1113	amino acid transport
EI070_18535	COG1113	amino acid transport
EI070_18540	COG0251	oxidation-reduction process
EI070_18555	COG1522	sequence-specific DNA binding
EI070_18580	COG0564	pseudouridine synthase activity
EI070_18645	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EI070_18660	COG1802	Transcriptional regulator
EI070_18670	COG1448	Aminotransferase
EI070_18675	COG0277	FAD linked oxidase domain protein
EI070_18685	COG2186	Transcriptional regulator
EI070_18695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EI070_18700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EI070_18715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EI070_18720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EI070_18725	COG1216	Glycosyl transferase, family 2
EI070_18755	COG2089	acid synthase
EI070_18770	COG1083	cytidylyl-transferase
EI070_18775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI070_18780	COG1086	Polysaccharide biosynthesis protein
EI070_18785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EI070_18795	COG1596	polysaccharide export
EI070_18820	COG0728	peptidoglycan biosynthetic process
EI070_18825	COG3023	N-Acetylmuramoyl-L-alanine amidase
EI070_18880	COG0546	phosphoglycolate phosphatase activity
EI070_18885	COG1028	Short-chain dehydrogenase reductase Sdr
EI070_18905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EI070_18910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EI070_18915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EI070_18920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EI070_18925	COG1116	anion transmembrane transporter activity
EI070_18930	COG1309	transcriptional regulator
EI070_18935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EI070_18945	COG0196	riboflavin kinase activity
EI070_18950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EI070_18960	COG1047	Peptidyl-prolyl cis-trans
EI070_19000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EI070_19055	COG2951	lytic endotransglycosylase activity
EI070_19060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EI070_19080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EI070_19090	COG0671	phosphoesterase, PA-phosphatase related
EI070_19095	COG0861	Integral membrane protein TerC family
EI070_19105	COG0754	glutathionylspermidine amidase activity
EI070_19115	COG0402	S-adenosylhomocysteine deaminase activity
EI070_19130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EI070_19135	COG1230	cation diffusion facilitator family transporter
EI070_19150	COG0706	membrane insertase activity
EI070_19165	COG0230	Belongs to the bacterial ribosomal protein bL34 family