locus-tag	class	description
OIO45_00010	COG0592	DNA-directed DNA polymerase activity
OIO45_00020	COG0187	DNA topoisomerase II activity
OIO45_00030	COG0586	Pfam SNARE associated Golgi protein
OIO45_00035	COG0488	(ABC) transporter
OIO45_00060	COG0596	Alpha beta hydrolase
OIO45_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OIO45_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO45_00110	COG0733	neurotransmitter:sodium symporter activity
OIO45_00150	COG2233	PERMEase
OIO45_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO45_00200	COG2814	Major facilitator Superfamily
OIO45_00205	COG0656	L-ascorbic acid biosynthetic process
OIO45_00210	COG0583	DNA-binding transcription factor activity
OIO45_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO45_00230	COG1064	alcohol dehydrogenase
OIO45_00235	COG2818	Glycosylase
OIO45_00250	COG1194	a g-specific adenine glycosylase
OIO45_00270	COG2983	Belongs to the UPF0260 family
OIO45_00280	COG3121	Chaperone
OIO45_00285	COG3188	usher protein
OIO45_00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OIO45_00305	COG2116	formate transmembrane transporter activity
OIO45_00325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO45_00330	COG1335	isochorismatase
OIO45_00335	COG0385	Bile acid
OIO45_00340	COG0534	Mate efflux family protein
OIO45_00345	COG1683	Conserved Protein
OIO45_00365	COG0625	glutathione transferase activity
OIO45_00375	COG1113	amino acid transport
OIO45_00385	COG0523	cobalamin synthesis protein
OIO45_00395	COG2188	Transcriptional regulator
OIO45_00425	COG0010	Belongs to the arginase family
OIO45_00445	COG1280	lysine exporter protein (LysE YggA)
OIO45_00470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIO45_00480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OIO45_00485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OIO45_00570	COG0534	Mate efflux family protein
OIO45_00575	COG0436	Aminotransferase
OIO45_00580	COG2733	membrane
OIO45_00595	COG2918	glutathione biosynthetic process
OIO45_00620	COG3150	esterase
OIO45_00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OIO45_00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO45_00650	COG2233	PERMEase
OIO45_00655	COG2351	hydroxyisourate hydrolase activity
OIO45_00690	COG3706	GGDEF domain
OIO45_00705	COG1393	Belongs to the ArsC family
OIO45_00710	COG0708	Exodeoxyribonuclease III
OIO45_00730	COG0189	ligase activity
OIO45_00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIO45_00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIO45_00775	COG4942	peptidase
OIO45_00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO45_00795	COG2119	membrane
OIO45_00800	COG4774	siderophore transport
OIO45_00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO45_00805	COG0426	domain, Protein
OIO45_00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OIO45_00855	COG1902	pentaerythritol trinitrate reductase activity
OIO45_00860	COG1519	Transferase
OIO45_00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO45_00870	COG0668	transmembrane transport
OIO45_00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO45_00885	COG1335	isochorismatase
OIO45_00890	COG1522	sequence-specific DNA binding
OIO45_00915	COG2198	Histidine kinase
OIO45_00915	COG2205	protein histidine kinase activity
OIO45_00915	COG0784	Response regulator, receiver
OIO45_00920	COG3162	membrane
OIO45_00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO45_00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO45_00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIO45_00960	COG1309	transcriptional regulator
OIO45_00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO45_00980	COG0352	thiamine-phosphate diphosphorylase activity
OIO45_00980	COG0351	phosphomethylpyrimidine kinase
OIO45_00990	COG2814	Major facilitator Superfamily
OIO45_01030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO45_01040	COG1113	amino acid transport
OIO45_01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO45_01055	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_01065	COG1335	isochorismatase
OIO45_01100	COG2814	Major facilitator Superfamily
OIO45_01105	COG0583	DNA-binding transcription factor activity
OIO45_01120	COG1309	transcriptional regulator
OIO45_01140	COG0667	Aldo Keto reductase
OIO45_01175	COG1733	regulation of RNA biosynthetic process
OIO45_01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO45_01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OIO45_01260	COG2329	Antibiotic biosynthesis monooxygenase
OIO45_01275	COG1132	(ABC) transporter
OIO45_01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIO45_01325	COG0427	acetyl-CoA hydrolase
OIO45_01350	COG0659	secondary active sulfate transmembrane transporter activity
OIO45_01355	COG4221	oxidoreductase activity
OIO45_01360	COG2873	o-acetylhomoserine
OIO45_01365	COG0488	(ABC) transporter
OIO45_01430	COG0833	amino acid
OIO45_01475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIO45_01480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIO45_01495	COG2226	methyltransferase
OIO45_01545	COG0070	glutamate synthase
OIO45_01545	COG0069	glutamate synthase activity
OIO45_01545	COG0067	glutamate synthase
OIO45_01550	COG0493	'glutamate synthase
OIO45_01560	COG1704	LemA family
OIO45_01565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OIO45_01580	COG3307	-O-antigen
OIO45_01600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO45_01615	COG0194	GDP metabolic process
OIO45_01670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIO45_01690	COG5380	lipid catabolic process
OIO45_01695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIO45_01720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIO45_01725	COG0277	FAD linked oxidase domain protein
OIO45_01735	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OIO45_01740	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO45_01755	COG1289	transmembrane transporter activity
OIO45_01765	COG0628	permease
OIO45_01770	COG1192	Involved in chromosome partitioning
OIO45_01800	COG0833	amino acid
OIO45_01805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO45_01810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO45_01820	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_01860	COG0583	DNA-binding transcription factor activity
OIO45_01885	COG0752	glycyl-tRNA synthetase alpha subunit
OIO45_01910	COG0517	IMP dehydrogenase activity
OIO45_01915	COG1983	PspC domain protein
OIO45_01925	COG1960	acyl-CoA dehydrogenase activity
OIO45_01940	COG0408	coproporphyrinogen oxidase activity
OIO45_01960	COG0513	Belongs to the DEAD box helicase family
OIO45_01970	COG1127	ABC transporter
OIO45_01975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIO45_01985	COG2854	intermembrane phospholipid transfer
OIO45_01995	COG0598	Magnesium transport protein CorA
OIO45_02005	COG0494	nUDIX hydrolase
OIO45_02010	COG1040	competence protein
OIO45_02015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIO45_02035	COG1946	Acyl-CoA thioesterase
OIO45_02040	COG1301	dicarboxylic acid transport
OIO45_02055	COG1959	2 iron, 2 sulfur cluster binding
OIO45_02060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO45_02060	COG1017	nitric oxide dioxygenase activity
OIO45_02225	COG1960	acyl-CoA dehydrogenase activity
OIO45_02230	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OIO45_02260	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OIO45_02265	COG0339	signal peptide processing
OIO45_02270	COG0557	exoribonuclease II activity
OIO45_02315	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO45_02320	COG2169	Transcriptional regulator
OIO45_02325	COG0697	spore germination
OIO45_02330	COG1295	ribonuclease BN
OIO45_02365	COG1702	phosphate starvation-inducible protein PhoH
OIO45_02375	COG0739	heme binding
OIO45_02375	COG0741	lytic transglycosylase activity
OIO45_02375	COG1196	nuclear chromosome segregation
OIO45_02405	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OIO45_02410	COG1183	phosphatidylcholine synthase activity
OIO45_02455	COG1960	acyl-CoA dehydrogenase activity
OIO45_02460	COG1309	transcriptional regulator
OIO45_02475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO45_02480	COG1960	acyl-CoA dehydrogenase activity
OIO45_02500	COG2969	positive regulation of protein catabolic process
OIO45_02510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIO45_02520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OIO45_02525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIO45_02530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIO45_02550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIO45_02560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO45_02565	COG1408	metallophosphoesterase
OIO45_02575	COG2199	diguanylate cyclase activity
OIO45_02635	COG1607	acyl-coa hydrolase
OIO45_02665	COG2350	Protein conserved in bacteria
OIO45_02675	COG0613	PHP domain protein
OIO45_02680	COG3781	membrane
OIO45_02690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIO45_02695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIO45_02705	COG1862	Preprotein translocase
OIO45_02735	COG2205	protein histidine kinase activity
OIO45_02740	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIO45_02760	COG0726	polysaccharide deacetylase
OIO45_02765	COG0463	Glycosyl transferase, family 2
OIO45_02770	COG0438	transferase activity, transferring glycosyl groups
OIO45_02835	COG1960	acyl-CoA dehydrogenase activity
OIO45_02840	COG1960	acyl-CoA dehydrogenase activity
OIO45_02850	COG2205	protein histidine kinase activity
OIO45_02855	COG0745	RESPONSE REGULATOR receiver
OIO45_02860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OIO45_02875	COG0584	glycerophosphoryl diester phosphodiesterase
OIO45_02880	COG2096	Adenosyltransferase
OIO45_02930	COG0285	dihydrofolate synthase activity
OIO45_02950	COG0450	alkyl hydroperoxide reductase
OIO45_02965	COG0477	Major facilitator Superfamily
OIO45_02970	COG1272	protein, Hemolysin III
OIO45_03000	COG0183	Belongs to the thiolase family
OIO45_03005	COG2207	Transcriptional regulator
OIO45_03025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO45_03045	COG0183	Belongs to the thiolase family
OIO45_03055	COG2885	chlorophyll binding
OIO45_03055	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OIO45_03065	COG1690	Belongs to the RtcB family
OIO45_03070	COG0833	amino acid
OIO45_03080	COG2233	PERMEase
OIO45_03085	COG1217	gtp-binding protein TYPA
OIO45_03110	COG2094	Belongs to the DNA glycosylase MPG family
OIO45_03115	COG4772	TonB-dependent receptor
OIO45_03120	COG1902	pentaerythritol trinitrate reductase activity
OIO45_03135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO45_03140	COG0354	folic acid binding
OIO45_03150	COG3189	MarR family transcriptional regulator
OIO45_03155	COG2824	Alkylphosphonate utilization operon protein PhnA
OIO45_03160	COG3422	double-strand break repair
OIO45_03200	COG0840	transmembrane signaling receptor activity
OIO45_03225	COG5510	response to toxic substance
OIO45_03235	COG2832	Protein of unknown function (DUF454)
OIO45_03240	COG1376	ErfK ybiS ycfS ynhG family protein
OIO45_03290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OIO45_03300	COG1289	transmembrane transporter activity
OIO45_03305	COG2814	Major facilitator Superfamily
OIO45_03325	COG1115	amino acid carrier protein
OIO45_03330	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO45_03335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO45_03340	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OIO45_03365	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO45_03375	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO45_03380	COG1077	Cell shape determining protein MreB Mrl
OIO45_03385	COG1792	Involved in formation and maintenance of cell shape
OIO45_03390	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OIO45_03395	COG0424	maF-like protein
OIO45_03400	COG1530	ribonuclease E activity
OIO45_03410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO45_03420	COG0560	Phosphoserine phosphatase
OIO45_03430	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO45_03455	COG2207	Transcriptional regulator
OIO45_03500	COG1113	amino acid transport
OIO45_03505	COG2828	Protein conserved in bacteria
OIO45_03510	COG0142	geranyltranstransferase activity
OIO45_03515	COG2315	Protein conserved in bacteria
OIO45_03530	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO45_03550	COG2194	sulfuric ester hydrolase activity
OIO45_03555	COG0745	RESPONSE REGULATOR receiver
OIO45_03560	COG0642	Histidine kinase
OIO45_03575	COG0004	ammonium transporteR
OIO45_03580	COG0583	DNA-binding transcription factor activity
OIO45_03600	COG0525	valine-tRNA ligase activity
OIO45_03610	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_03620	COG0393	Putative heavy-metal-binding
OIO45_03625	COG0393	Putative heavy-metal-binding
OIO45_03630	COG1538	Outer membrane efflux protein
OIO45_03640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO45_03675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OIO45_03690	COG1648	precorrin-2 dehydrogenase activity
OIO45_03690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIO45_03695	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIO45_03700	COG1733	regulation of RNA biosynthetic process
OIO45_03710	COG0531	amino acid
OIO45_03725	COG0321	lipoyl(octanoyl) transferase activity
OIO45_03730	COG2921	Belongs to the UPF0250 family
OIO45_03765	COG2009	succinate dehydrogenase
OIO45_03770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OIO45_03775	COG1053	succinate dehydrogenase
OIO45_03780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIO45_03805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO45_03825	COG2354	Protein conserved in bacteria
OIO45_03830	COG2321	neutral zinc metallopeptidase
OIO45_03850	COG2843	Capsule synthesis protein
OIO45_03865	COG0589	response to stress
OIO45_03885	COG0505	Belongs to the CarA family
OIO45_03910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO45_03915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIO45_03965	COG0477	Major facilitator Superfamily
OIO45_03970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIO45_03985	COG1597	lipid kinase activity
OIO45_03990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO45_04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO45_04020	COG0584	glycerophosphoryl diester phosphodiesterase
OIO45_04040	COG0741	lytic transglycosylase activity
OIO45_04060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIO45_04075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO45_04100	COG3811	Belongs to the UPF0386 family
OIO45_04125	COG0778	Nitroreductase
OIO45_04140	COG1929	Belongs to the glycerate kinase type-1 family
OIO45_04145	COG0243	molybdopterin cofactor binding
OIO45_04150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIO45_04155	COG3339	Conserved Protein
OIO45_04165	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OIO45_04180	COG1113	amino acid transport
OIO45_04190	COG0019	diaminopimelate decarboxylase activity
OIO45_04200	COG2267	carboxylic ester hydrolase activity
OIO45_04205	COG1280	lysine exporter protein (LysE YggA)
OIO45_04210	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO45_04240	COG0463	Glycosyl transferase, family 2
OIO45_04260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO45_04295	COG4591	ABC-type transport system involved in lipoprotein release permease component
OIO45_04300	COG1136	(ABC) transporter
OIO45_04305	COG0658	competence protein
OIO45_04305	COG2333	competence protein COMEC
OIO45_04315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIO45_04315	COG0616	signal peptide processing
OIO45_04320	COG0596	Alpha beta hydrolase
OIO45_04325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIO45_04335	COG0628	permease
OIO45_04370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO45_04390	COG0823	Involved in the tonB-independent uptake of proteins
OIO45_04410	COG0824	Thioesterase
OIO45_04415	COG1473	amidohydrolase
OIO45_04435	COG0047	phosphoribosylformylglycinamidine synthase activity
OIO45_04435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIO45_04440	COG2814	Major facilitator Superfamily
OIO45_04455	COG1024	Enoyl-CoA hydratase
OIO45_04460	COG1051	belongs to the nudix hydrolase family
OIO45_04460	COG1056	cytidyltransferase-related domain
OIO45_04470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OIO45_04485	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OIO45_04500	COG4625	pathogenesis
OIO45_04505	COG0583	DNA-binding transcription factor activity
OIO45_04510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OIO45_04515	COG4208	sulfate ABC transporter
OIO45_04520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIO45_04530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OIO45_04535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIO45_04540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIO45_04560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO45_04570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIO45_04580	COG0681	Belongs to the peptidase S26 family
OIO45_04595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIO45_04605	COG1381	Involved in DNA repair and RecF pathway recombination
OIO45_04610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OIO45_04620	COG4221	oxidoreductase activity
OIO45_04650	COG0443	Heat shock 70 kDa protein
OIO45_04660	COG0436	Aminotransferase
OIO45_04680	COG0556	nucleotide-excision repair
OIO45_04735	COG2070	2-Nitropropane dioxygenase
OIO45_04750	COG1252	NADH dehydrogenase
OIO45_04755	COG1686	Belongs to the peptidase S11 family
OIO45_04770	COG1187	pseudouridine synthase activity
OIO45_04965	COG4695	Portal protein
OIO45_05100	COG0582	viral genome integration into host DNA
OIO45_05125	COG0477	Major facilitator Superfamily
OIO45_05130	COG0583	DNA-binding transcription factor activity
OIO45_05135	COG1823	symporter activity
OIO45_05145	COG0612	Peptidase, M16
OIO45_05170	COG0352	thiamine-phosphate diphosphorylase activity
OIO45_05205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO45_05220	COG1309	transcriptional regulator
OIO45_05230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO45_05235	COG0076	glutamate decarboxylase activity
OIO45_05245	COG1522	sequence-specific DNA binding
OIO45_05250	COG3961	Belongs to the TPP enzyme family
OIO45_05255	COG1113	amino acid transport
OIO45_05260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIO45_05265	COG0573	inorganic phosphate transmembrane transporter activity
OIO45_05275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIO45_05280	COG0616	signal peptide processing
OIO45_05315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OIO45_05320	COG1686	Belongs to the peptidase S11 family
OIO45_05345	COG0583	DNA-binding transcription factor activity
OIO45_05350	COG1067	ATP-dependent peptidase activity
OIO45_05375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OIO45_05400	COG1966	Carbon starvation protein
OIO45_05405	COG2879	small protein
OIO45_05445	COG1335	isochorismatase
OIO45_05450	COG0583	DNA-binding transcription factor activity
OIO45_05465	COG0596	Alpha beta hydrolase
OIO45_05475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO45_05485	COG2130	NADP-dependent
OIO45_05515	COG1741	Belongs to the pirin family
OIO45_05525	COG2964	Protein conserved in bacteria
OIO45_05540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO45_05550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO45_05555	COG4605	iron ion homeostasis
OIO45_05560	COG4604	ABC transporter, ATP-binding protein
OIO45_05565	COG4607	ABC-type enterochelin transport system periplasmic component
OIO45_05570	COG4774	siderophore transport
OIO45_05580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO45_05585	COG1021	2,3-dihydroxybenzoate-AMP ligase
OIO45_05590	COG3433	isochorismatase activity
OIO45_05590	COG1535	isochorismatase
OIO45_05605	COG1132	(ABC) transporter
OIO45_05610	COG1132	(ABC) transporter
OIO45_05615	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OIO45_05620	COG2977	Belongs to the P-Pant transferase superfamily
OIO45_05640	COG3739	integral membrane protein
OIO45_05660	COG0302	gtp cyclohydrolase
OIO45_05670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIO45_05700	COG0308	aminopeptidase N
OIO45_05705	COG0512	Glutamine amidotransferase of anthranilate synthase
OIO45_05720	COG0174	glutamine synthetase
OIO45_05730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OIO45_05765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIO45_05770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIO45_05775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO45_05795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO45_05800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIO45_05805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIO45_05820	COG1960	acyl-CoA dehydrogenase activity
OIO45_05825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO45_05830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO45_05840	COG2223	nitrite transmembrane transporter activity
OIO45_05860	COG0024	Methionine aminopeptidase
OIO45_05865	COG0052	Belongs to the universal ribosomal protein uS2 family
OIO45_05880	COG2207	Transcriptional regulator
OIO45_05905	COG2951	lytic endotransglycosylase activity
OIO45_05910	COG0772	Belongs to the SEDS family
OIO45_05925	COG0842	Transport permease protein
OIO45_05930	COG1131	(ABC) transporter
OIO45_05975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO45_05990	COG4215	(ABC) transporter
OIO45_05995	COG4160	amino acid transport
OIO45_06000	COG4598	ABC transporter
OIO45_06010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO45_06015	COG0826	peptidase U32
OIO45_06020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO45_06035	COG1720	tRNA m6t6A37 methyltransferase activity
OIO45_06045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OIO45_06060	COG0642	Histidine kinase
OIO45_06070	COG0494	nUDIX hydrolase
OIO45_06080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIO45_06085	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIO45_06090	COG3139	Protein of unknown function (DUF1315)
OIO45_06100	COG1301	dicarboxylic acid transport
OIO45_06105	COG1960	acyl-CoA dehydrogenase activity
OIO45_06110	COG2819	hydrolase of the alpha beta superfamily
OIO45_06120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIO45_06130	COG2195	Cleaves the N-terminal amino acid of tripeptides
OIO45_06150	COG1690	Belongs to the RtcB family
OIO45_06155	COG1234	tRNA 3'-trailer cleavage
OIO45_06160	COG4650	regulator
OIO45_06190	COG2363	Small membrane protein
OIO45_06215	COG0513	Belongs to the DEAD box helicase family
OIO45_06225	COG0778	Nitroreductase
OIO45_06255	COG1286	toxin biosynthetic process
OIO45_06280	COG4783	chaperone-mediated protein folding
OIO45_06285	COG1610	YqeY-like protein
OIO45_06315	COG0515	serine threonine protein kinase
OIO45_06315	COG2815	serine threonine protein kinase
OIO45_06385	COG3111	PFAM Bacterial OB fold (BOF) protein
OIO45_06410	COG3243	poly(R)-hydroxyalkanoic acid synthase
OIO45_06415	COG0786	glutamate:sodium symporter activity
OIO45_06425	COG2186	Transcriptional regulator
OIO45_06435	COG0477	Major facilitator Superfamily
OIO45_06465	COG2995	paraquat-inducible protein a
OIO45_06470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIO45_06470	COG3008	intermembrane lipid transfer
OIO45_06480	COG1794	racemase activity, acting on amino acids and derivatives
OIO45_06510	COG1301	dicarboxylic acid transport
OIO45_06520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO45_06525	COG2011	ABC-type metal ion transport system permease component
OIO45_06530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO45_06535	COG1464	Belongs to the NlpA lipoprotein family
OIO45_06540	COG0151	Belongs to the GarS family
OIO45_06545	COG0138	bifunctional purine biosynthesis protein purh
OIO45_06550	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OIO45_06580	COG2308	Evidence 4 Homologs of previously reported genes of
OIO45_06590	COG1305	Transglutaminase-like
OIO45_06600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIO45_06605	COG0305	Participates in initiation and elongation during chromosome replication
OIO45_06630	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OIO45_06640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIO45_06645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIO45_06670	COG0726	polysaccharide deacetylase
OIO45_06670	COG1649	PFAM Uncharacterised BCR, COG1649
OIO45_06675	COG1215	transferase activity, transferring glycosyl groups
OIO45_06680	COG3658	cytochrome
OIO45_06690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO45_06705	COG0583	DNA-binding transcription factor activity
OIO45_06725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO45_06730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO45_06745	COG1960	acyl-CoA dehydrogenase activity
OIO45_06750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO45_06755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO45_06770	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OIO45_06780	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIO45_06785	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIO45_06800	COG0745	RESPONSE REGULATOR receiver
OIO45_06805	COG0174	glutamine synthetase
OIO45_06825	COG0729	surface antigen
OIO45_06850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO45_06855	COG2814	Major facilitator Superfamily
OIO45_06870	COG0583	DNA-binding transcription factor activity
OIO45_06885	COG1187	pseudouridine synthase activity
OIO45_06905	COG0802	atpase or kinase
OIO45_06910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIO45_06920	COG1923	regulation of RNA biosynthetic process
OIO45_06925	COG0697	spore germination
OIO45_06950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO45_06955	COG0519	Catalyzes the synthesis of GMP from XMP
OIO45_06955	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO45_06960	COG4302	ethanolamine ammonia-lyase activity
OIO45_06965	COG4303	Ethanolamine ammonia lyase large subunit
OIO45_06970	COG0531	amino acid
OIO45_06990	COG1454	alcohol dehydrogenase
OIO45_06995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO45_07005	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OIO45_07025	COG0308	aminopeptidase N
OIO45_07045	COG1605	Chorismate mutase
OIO45_07065	COG1309	transcriptional regulator
OIO45_07075	COG0668	transmembrane transport
OIO45_07105	COG4773	Receptor
OIO45_07125	COG0488	(ABC) transporter
OIO45_07130	COG0589	response to stress
OIO45_07155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIO45_07165	COG3135	benzoate transporter
OIO45_07170	COG1522	sequence-specific DNA binding
OIO45_07180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIO45_07185	COG0583	DNA-binding transcription factor activity
OIO45_07195	COG0183	Belongs to the thiolase family
OIO45_07205	COG2030	dehydratase
OIO45_07210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO45_07225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIO45_07240	COG0824	Thioesterase
OIO45_07245	COG1454	alcohol dehydrogenase
OIO45_07255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIO45_07275	COG0069	glutamate synthase activity
OIO45_07295	COG2814	Major facilitator Superfamily
OIO45_07310	COG0511	ligase activity, forming carbon-carbon bonds
OIO45_07330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO45_07330	COG1116	anion transmembrane transporter activity
OIO45_07335	COG0745	RESPONSE REGULATOR receiver
OIO45_07345	COG2146	nitrite reductase [NAD(P)H] activity
OIO45_07345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO45_07350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO45_07355	COG0243	molybdopterin cofactor binding
OIO45_07365	COG0243	molybdopterin cofactor binding
OIO45_07385	COG0315	cyclic pyranopterin monophosphate synthase activity
OIO45_07385	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIO45_07400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO45_07405	COG0697	spore germination
OIO45_07425	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OIO45_07430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO45_07485	COG2204	response regulator
OIO45_07490	COG3852	Histidine kinase
OIO45_07510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIO45_07515	COG0575	Belongs to the CDS family
OIO45_07530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO45_07550	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO45_07565	COG2137	regulation of response to DNA damage stimulus
OIO45_07575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OIO45_07580	COG1011	Hydrolase
OIO45_07605	COG1522	sequence-specific DNA binding
OIO45_07615	COG1113	amino acid transport
OIO45_07635	COG0659	secondary active sulfate transmembrane transporter activity
OIO45_07640	COG2135	peptidase activity
OIO45_07655	COG3300	MHYT domain
OIO45_07655	COG5001	Diguanylate cyclase
OIO45_07675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO45_07675	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIO45_07675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO45_07680	COG1105	Belongs to the carbohydrate kinase PfkB family
OIO45_07685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIO45_07685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO45_07715	COG0024	Methionine aminopeptidase
OIO45_07720	COG0583	DNA-binding transcription factor activity
OIO45_07730	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OIO45_07735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO45_07740	COG0516	GMP reductase activity
OIO45_07740	COG0517	IMP dehydrogenase activity
OIO45_07765	COG0552	protein localization to endoplasmic reticulum
OIO45_07775	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OIO45_07785	COG4890	Cyd operon protein YbgT
OIO45_07790	COG1294	oxidase, subunit
OIO45_07805	COG1585	Membrane protein implicated in regulation of membrane protease activity
OIO45_07815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIO45_07820	COG4774	siderophore transport
OIO45_07835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIO45_07840	COG0569	domain protein
OIO45_07845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO45_07875	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIO45_07880	COG0542	response to heat
OIO45_07890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO45_07905	COG1902	pentaerythritol trinitrate reductase activity
OIO45_07905	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO45_07950	COG2323	membrane
OIO45_07955	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OIO45_07965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO45_07970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO45_07975	COG0183	Belongs to the thiolase family
OIO45_07980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIO45_07985	COG0596	Alpha beta hydrolase
OIO45_07990	COG2271	Major facilitator Superfamily
OIO45_07995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO45_08000	COG3485	protocatechuate 3,4-dioxygenase
OIO45_08005	COG3485	protocatechuate 3,4-dioxygenase
OIO45_08010	COG0710	3-dehydroquinate dehydratase activity
OIO45_08015	COG3420	alginic acid biosynthetic process
OIO45_08020	COG3659	wide pore channel activity
OIO45_08025	COG4993	Dehydrogenase
OIO45_08035	COG2391	methyltransferase activity
OIO45_08050	COG1414	Transcriptional regulator
OIO45_08055	COG0583	DNA-binding transcription factor activity
OIO45_08060	COG1960	acyl-CoA dehydrogenase activity
OIO45_08085	COG2814	Major facilitator Superfamily
OIO45_08095	COG0154	amidase activity
OIO45_08115	COG4638	Rieske (2fe-2S)
OIO45_08125	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_08135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO45_08145	COG3733	amine oxidase
OIO45_08155	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_08165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO45_08170	COG0183	Belongs to the thiolase family
OIO45_08175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO45_08180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO45_08190	COG4829	muconolactone delta-isomerase
OIO45_08195	COG4948	Mandelate Racemase Muconate Lactonizing
OIO45_08200	COG0583	DNA-binding transcription factor activity
OIO45_08210	COG2186	Transcriptional regulator
OIO45_08230	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_08235	COG3231	kanamycin kinase activity
OIO45_08250	COG1960	acyl-CoA dehydrogenase activity
OIO45_08255	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_08260	COG3829	transcription factor binding
OIO45_08270	COG3162	membrane
OIO45_08285	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_08300	COG0753	catalase activity
OIO45_08325	COG1846	Transcriptional regulator
OIO45_08330	COG1902	pentaerythritol trinitrate reductase activity
OIO45_08330	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO45_08365	COG1309	transcriptional regulator
OIO45_08375	COG1335	isochorismatase
OIO45_08380	COG0583	DNA-binding transcription factor activity
OIO45_08390	COG0475	glutathione-regulated potassium exporter activity
OIO45_08390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO45_08400	COG1473	amidohydrolase
OIO45_08455	COG2188	Transcriptional regulator
OIO45_08470	COG0583	DNA-binding transcription factor activity
OIO45_08505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO45_08525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO45_08545	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_08560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO45_08565	COG2814	Major facilitator Superfamily
OIO45_08575	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO45_08585	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_08590	COG3384	dioxygenase
OIO45_08600	COG3971	2-oxopent-4-enoate hydratase activity
OIO45_08615	COG0477	Major facilitator Superfamily
OIO45_08620	COG1960	acyl-CoA dehydrogenase activity
OIO45_08625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO45_08630	COG1846	Transcriptional regulator
OIO45_08635	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_08640	COG0129	dihydroxy-acid dehydratase activity
OIO45_08650	COG0583	DNA-binding transcription factor activity
OIO45_08655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO45_08665	COG2084	Dehydrogenase
OIO45_08670	COG2207	Transcriptional regulator
OIO45_08685	COG1064	alcohol dehydrogenase
OIO45_08695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO45_08700	COG1120	ATPase activity
OIO45_08720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO45_08770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OIO45_08795	COG2814	Major facilitator Superfamily
OIO45_08800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO45_08800	COG3320	Male sterility
OIO45_08830	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_08840	COG2207	Transcriptional regulator
OIO45_08850	COG2205	protein histidine kinase activity
OIO45_08855	COG0745	RESPONSE REGULATOR receiver
OIO45_08860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO45_08865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO45_08890	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO45_08900	COG0753	catalase activity
OIO45_08920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO45_08980	COG1535	isochorismatase
OIO45_08980	COG3433	isochorismatase activity
OIO45_08985	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_08990	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OIO45_08995	COG4149	molybdate abc transporter
OIO45_09000	COG0725	ABC transporter, periplasmic molybdate-binding protein
OIO45_09010	COG4638	Rieske (2fe-2S)
OIO45_09015	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO45_09020	COG0543	2 iron, 2 sulfur cluster binding
OIO45_09020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO45_09035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO45_09045	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_09060	COG2207	Transcriptional regulator
OIO45_09065	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_09070	COG2610	gluconate transmembrane transporter activity
OIO45_09080	COG0583	DNA-binding transcription factor activity
OIO45_09095	COG2031	fatty acid transporter
OIO45_09100	COG0183	Belongs to the thiolase family
OIO45_09105	COG0583	DNA-binding transcription factor activity
OIO45_09110	COG0583	DNA-binding transcription factor activity
OIO45_09125	COG1027	Aspartate ammonia-lyase
OIO45_09135	COG0477	Major facilitator Superfamily
OIO45_09155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO45_09160	COG4521	taurine ABC transporter
OIO45_09175	COG2188	Transcriptional regulator
OIO45_09185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIO45_09190	COG1733	regulation of RNA biosynthetic process
OIO45_09195	COG2207	Transcriptional regulator
OIO45_09195	COG3708	Transcriptional regulator
OIO45_09210	COG0730	response to heat
OIO45_09225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO45_09225	COG3453	Protein conserved in bacteria
OIO45_09235	COG3781	membrane
OIO45_09240	COG1063	alcohol dehydrogenase
OIO45_09250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO45_09255	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO45_09260	COG0022	dehydrogenase e1 component
OIO45_09265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OIO45_09270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO45_09285	COG3706	GGDEF domain
OIO45_09300	COG0133	tryptophan synthase activity
OIO45_09310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO45_09345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIO45_09370	COG2226	methyltransferase
OIO45_09425	COG0842	Transport permease protein
OIO45_09430	COG0842	Transport permease protein
OIO45_09435	COG1131	(ABC) transporter
OIO45_09450	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO45_09475	COG0730	response to heat
OIO45_09480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO45_09495	COG0406	alpha-ribazole phosphatase activity
OIO45_09500	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIO45_09515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO45_09545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO45_09555	COG4264	IucA IucC family
OIO45_09560	COG4264	IucA IucC family
OIO45_09565	COG2814	Major facilitator Superfamily
OIO45_09580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIO45_09595	COG1960	acyl-CoA dehydrogenase activity
OIO45_09600	COG1960	acyl-CoA dehydrogenase activity
OIO45_09605	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO45_09610	COG2207	Transcriptional regulator
OIO45_09615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO45_09620	COG0776	regulation of translation
OIO45_09645	COG0822	iron-sulfur transferase activity
OIO45_09650	COG0316	Belongs to the HesB IscA family
OIO45_09680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO45_09700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO45_09705	COG0702	epimerase
OIO45_09740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIO45_09750	COG0339	signal peptide processing
OIO45_09760	COG4166	transmembrane transport
OIO45_09795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIO45_09800	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OIO45_09830	COG0776	regulation of translation
OIO45_09895	COG0084	hydrolase, TatD family'
OIO45_09915	COG1663	tetraacyldisaccharide 4'-kinase activity
OIO45_09920	COG1132	(ABC) transporter
OIO45_09930	COG0811	peptide transport
OIO45_09935	COG1475	DNA binding
OIO45_09940	COG1192	Involved in chromosome partitioning
OIO45_09950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIO45_09965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO45_09970	COG0191	fructose-bisphosphate aldolase activity
OIO45_09990	COG0424	maF-like protein
OIO45_09995	COG2850	peptidyl-arginine hydroxylation
OIO45_10005	COG0640	Transcriptional regulator
OIO45_10015	COG3619	membrane
OIO45_10020	COG3122	Protein conserved in bacteria
OIO45_10025	COG1132	(ABC) transporter
OIO45_10045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIO45_10050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO45_10060	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO45_10060	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO45_10060	COG0506	proline dehydrogenase activity
OIO45_10065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIO45_10080	COG3698	Phosphodiester glycosidase
OIO45_10090	COG2353	YceI-like domain
OIO45_10100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIO45_10145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIO45_10145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIO45_10170	COG3539	Fimbrial protein
OIO45_10175	COG3121	Chaperone
OIO45_10200	COG0697	spore germination
OIO45_10210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO45_10220	COG0583	DNA-binding transcription factor activity
OIO45_10240	COG1309	transcriptional regulator
OIO45_10255	COG1522	sequence-specific DNA binding
OIO45_10265	COG1126	abc transporter atp-binding protein
OIO45_10270	COG0765	amino acid transport
OIO45_10275	COG0765	amino acid transport
OIO45_10305	COG1464	Belongs to the NlpA lipoprotein family
OIO45_10315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO45_10320	COG2011	ABC-type metal ion transport system permease component
OIO45_10325	COG0012	GTP binding
OIO45_10350	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO45_10390	COG0386	Belongs to the glutathione peroxidase family
OIO45_10400	COG0436	Aminotransferase
OIO45_10405	COG1301	dicarboxylic acid transport
OIO45_10440	COG3634	alkyl hydroperoxide reductase activity
OIO45_10455	COG0583	DNA-binding transcription factor activity
OIO45_10460	COG0798	PFAM Bile acid sodium symporter
OIO45_10465	COG0640	Transcriptional regulator
OIO45_10480	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIO45_10490	COG0583	DNA-binding transcription factor activity
OIO45_10500	COG1953	Uracil, thiamine, allantoin
OIO45_10510	COG2175	clavaminate synthase activity
OIO45_10515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO45_10535	COG4521	taurine ABC transporter
OIO45_10545	COG0477	Major facilitator Superfamily
OIO45_10565	COG1271	oxidase subunit
OIO45_10570	COG1294	oxidase, subunit
OIO45_10580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO45_10600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OIO45_10620	COG3052	prosthetic group binding
OIO45_10625	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OIO45_10635	COG0583	DNA-binding transcription factor activity
OIO45_10645	COG2814	Major facilitator Superfamily
OIO45_10665	COG1346	cytolysis
OIO45_10675	COG0583	DNA-binding transcription factor activity
OIO45_10680	COG0625	glutathione transferase activity
OIO45_10685	COG0625	glutathione transferase activity
OIO45_10690	COG0583	DNA-binding transcription factor activity
OIO45_10695	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_10705	COG1045	serine acetyltransferase
OIO45_10710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO45_10715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIO45_10725	COG1280	lysine exporter protein (LysE YggA)
OIO45_10740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO45_10745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO45_10750	COG1126	abc transporter atp-binding protein
OIO45_10755	COG0765	amino acid transport
OIO45_10760	COG0765	amino acid transport
OIO45_10780	COG2205	protein histidine kinase activity
OIO45_10780	COG0784	Response regulator, receiver
OIO45_10800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIO45_10820	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_10870	COG0583	DNA-binding transcription factor activity
OIO45_10890	COG0318	PFAM AMP-dependent synthetase and ligase
OIO45_10895	COG1309	transcriptional regulator
OIO45_10900	COG1960	acyl-CoA dehydrogenase activity
OIO45_10905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO45_10910	COG1024	Enoyl-CoA hydratase
OIO45_10915	COG4770	biotin carboxylase activity
OIO45_10925	COG0583	DNA-binding transcription factor activity
OIO45_10945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO45_10965	COG3842	ATPase activity
OIO45_10970	COG1840	ABC-type Fe3 transport system, periplasmic component
OIO45_10985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO45_10990	COG1414	Transcriptional regulator
OIO45_11000	COG0583	DNA-binding transcription factor activity
OIO45_11005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO45_11010	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_11020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO45_11030	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_11035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO45_11040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO45_11045	COG2267	carboxylic ester hydrolase activity
OIO45_11065	COG3038	cytochrome b561
OIO45_11070	COG0753	catalase activity
OIO45_11075	COG2271	Major facilitator Superfamily
OIO45_11080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO45_11085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO45_11110	COG2207	Transcriptional regulator
OIO45_11120	COG1278	Cold shock
OIO45_11155	COG0556	nucleotide-excision repair
OIO45_11165	COG2050	protein possibly involved in aromatic compounds catabolism
OIO45_11175	COG3327	negative regulation of DNA-templated transcription, initiation
OIO45_11180	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OIO45_11185	COG0183	Belongs to the thiolase family
OIO45_11190	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO45_11195	COG1024	Enoyl-CoA hydratase
OIO45_11200	COG1024	Enoyl-CoA hydratase
OIO45_11205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO45_11210	COG2151	metal-sulfur cluster biosynthetic enzyme
OIO45_11215	COG3396	Phenylacetate-CoA oxygenase
OIO45_11220	COG3460	Phenylacetate-CoA oxygenase
OIO45_11225	COG3396	Phenylacetate-CoA oxygenase
OIO45_11230	COG2030	dehydratase
OIO45_11230	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_11235	COG1760	l-serine dehydratase
OIO45_11240	COG0531	amino acid
OIO45_11245	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_11270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO45_11290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO45_11300	COG0789	Transcriptional regulator
OIO45_11310	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OIO45_11325	COG2807	transmembrane transport
OIO45_11330	COG0590	tRNA wobble adenosine to inosine editing
OIO45_11460	COG1116	anion transmembrane transporter activity
OIO45_11465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO45_11475	COG0864	Transcriptional regulator
OIO45_11485	COG1733	regulation of RNA biosynthetic process
OIO45_11490	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO45_11495	COG0439	Biotin carboxylase
OIO45_11510	COG1063	alcohol dehydrogenase
OIO45_11520	COG1309	transcriptional regulator
OIO45_11560	COG0038	chloride channel
OIO45_11565	COG4770	biotin carboxylase activity
OIO45_11585	COG1914	H( )-stimulated, divalent metal cation uptake system
OIO45_11645	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO45_11670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO45_11675	COG1116	anion transmembrane transporter activity
OIO45_11680	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO45_11710	COG0598	Magnesium transport protein CorA
OIO45_11720	COG1560	Kdo2-lipid A biosynthetic process
OIO45_11730	COG5006	permease, DMT superfamily
OIO45_11735	COG1522	sequence-specific DNA binding
OIO45_11750	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OIO45_11760	COG4122	O-methyltransferase activity
OIO45_11795	COG1137	ATPase activity
OIO45_11800	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OIO45_11810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OIO45_11815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OIO45_11815	COG0517	IMP dehydrogenase activity
OIO45_11855	COG2814	Major facilitator Superfamily
OIO45_11890	COG1278	Cold shock
OIO45_11895	COG1280	lysine exporter protein (LysE YggA)
OIO45_11925	COG1570	exodeoxyribonuclease VII activity
OIO45_11975	COG0583	DNA-binding transcription factor activity
OIO45_11985	COG4638	Rieske (2fe-2S)
OIO45_11995	COG0543	2 iron, 2 sulfur cluster binding
OIO45_11995	COG0633	Ferredoxin
OIO45_12000	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_12005	COG3135	benzoate transporter
OIO45_12010	COG2814	Major facilitator Superfamily
OIO45_12025	COG1643	Atp-dependent helicase
OIO45_12030	COG0450	alkyl hydroperoxide reductase
OIO45_12040	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIO45_12050	COG3634	alkyl hydroperoxide reductase activity
OIO45_12070	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIO45_12230	COG0625	glutathione transferase activity
OIO45_12240	COG2885	chlorophyll binding
OIO45_12275	COG0542	response to heat
OIO45_12290	COG1765	OsmC-like protein
OIO45_12305	COG0667	Aldo Keto reductase
OIO45_12320	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIO45_12335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIO45_12345	COG0527	aspartate kinase activity
OIO45_12355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIO45_12365	COG3038	cytochrome b561
OIO45_12370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIO45_12375	COG2252	PERMEase
OIO45_12385	COG2072	flavoprotein involved in K transport
OIO45_12400	COG1741	Belongs to the pirin family
OIO45_12405	COG1309	transcriptional regulator
OIO45_12415	COG0300	oxidoreductase activity
OIO45_12420	COG2072	flavoprotein involved in K transport
OIO45_12425	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIO45_12470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO45_12490	COG2814	Major facilitator Superfamily
OIO45_12495	COG1024	Enoyl-CoA hydratase
OIO45_12500	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_12510	COG1960	acyl-CoA dehydrogenase activity
OIO45_12535	COG2186	Transcriptional regulator
OIO45_12540	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_12550	COG4948	Mandelate Racemase Muconate Lactonizing
OIO45_12555	COG2271	Major facilitator Superfamily
OIO45_12560	COG2721	sulfolactate sulfo-lyase activity
OIO45_12565	COG0697	spore germination
OIO45_12610	COG1113	amino acid transport
OIO45_12630	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_12650	COG0531	amino acid
OIO45_12660	COG1113	amino acid transport
OIO45_12700	COG3209	COG3209 Rhs family protein
OIO45_12720	COG4269	membrane
OIO45_12735	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO45_12735	COG1902	pentaerythritol trinitrate reductase activity
OIO45_12745	COG4251	negative regulation of phosphorylation
OIO45_12745	COG5001	Diguanylate cyclase
OIO45_12745	COG2203	Gaf domain
OIO45_12745	COG3706	GGDEF domain
OIO45_12755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO45_12780	COG4172	Belongs to the ABC transporter superfamily
OIO45_12785	COG4239	(ABC) transporter, permease
OIO45_12790	COG4174	ABC transporter (Permease)
OIO45_12800	COG0741	lytic transglycosylase activity
OIO45_12800	COG1388	LysM domain
OIO45_12800	COG0741	lytic transglycosylase activity
OIO45_12800	COG1388	LysM domain
OIO45_12805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO45_12845	COG0583	DNA-binding transcription factor activity
OIO45_12850	COG1279	arginine transmembrane transporter activity
OIO45_12870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO45_12875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO45_12880	COG0006	proline dipeptidase activity
OIO45_12915	COG2194	sulfuric ester hydrolase activity
OIO45_13080	COG5410	chromosome segregation
OIO45_13260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIO45_13280	COG3384	dioxygenase
OIO45_13290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO45_13295	COG2878	Part of a membrane complex involved in electron transport
OIO45_13300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIO45_13325	COG0768	penicillin binding
OIO45_13330	COG0742	ribosomal rna small subunit methyltransferase
OIO45_13345	COG0830	nickel cation binding
OIO45_13355	COG0804	urea catabolic process
OIO45_13395	COG1253	flavin adenine dinucleotide binding
OIO45_13400	COG2851	Citrate transporter
OIO45_13450	COG1773	rubredoxin
OIO45_13455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO45_13465	COG0583	DNA-binding transcription factor activity
OIO45_13495	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OIO45_13500	COG4181	ATPase activity
OIO45_13545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIO45_13570	COG0306	phosphate transporter
OIO45_13580	COG3958	Transketolase
OIO45_13585	COG3959	Transketolase, thiamine diphosphate binding domain
OIO45_13590	COG2271	Major facilitator Superfamily
OIO45_13595	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_13600	COG0583	DNA-binding transcription factor activity
OIO45_13620	COG2207	Transcriptional regulator
OIO45_13625	COG2066	Belongs to the glutaminase family
OIO45_13630	COG0242	peptide deformylase activity
OIO45_13635	COG0477	Major facilitator Superfamily
OIO45_13645	COG0028	Belongs to the TPP enzyme family
OIO45_13660	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_13665	COG2267	carboxylic ester hydrolase activity
OIO45_13675	COG2271	Major facilitator Superfamily
OIO45_13680	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO45_13690	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_13710	COG1414	Transcriptional regulator
OIO45_13725	COG1024	Enoyl-CoA hydratase
OIO45_13735	COG1215	transferase activity, transferring glycosyl groups
OIO45_13740	COG0726	polysaccharide deacetylase
OIO45_13740	COG1649	PFAM Uncharacterised BCR, COG1649
OIO45_13750	COG4681	YaeQ
OIO45_13760	COG0523	cobalamin synthesis protein
OIO45_13770	COG1607	acyl-coa hydrolase
OIO45_13780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO45_13785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO45_13790	COG1309	transcriptional regulator
OIO45_13815	COG2040	homocysteine
OIO45_13820	COG0531	amino acid
OIO45_13875	COG1595	DNA-templated transcription, initiation
OIO45_13885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO45_13890	COG0477	Major facilitator Superfamily
OIO45_13900	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OIO45_13965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO45_14050	COG0592	DNA-directed DNA polymerase activity
OIO45_14090	COG2026	Addiction module toxin, RelE StbE family
OIO45_14310	COG1484	DNA-dependent DNA replication
OIO45_14395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO45_14475	COG0405	Gamma-glutamyltransferase
OIO45_14480	COG2814	Major facilitator Superfamily
OIO45_14490	COG2050	protein possibly involved in aromatic compounds catabolism
OIO45_14505	COG1090	epimerase
OIO45_14525	COG0420	3'-5' exonuclease activity
OIO45_14550	COG0735	belongs to the Fur family
OIO45_14555	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO45_14575	COG0121	glutamine amidotransferase
OIO45_14590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO45_14600	COG0210	DNA helicase
OIO45_14605	COG2885	chlorophyll binding
OIO45_14610	COG0204	Acyl-transferase
OIO45_14625	COG2894	cell division
OIO45_14640	COG1280	lysine exporter protein (LysE YggA)
OIO45_14645	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OIO45_14645	COG1674	ftsk spoiiie
OIO45_14650	COG0492	ferredoxin-NADP+ reductase activity
OIO45_14655	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OIO45_14665	COG0456	acetyltransferase
OIO45_14710	COG1981	membrane
OIO45_14725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO45_14725	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIO45_14745	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_14755	COG0657	acetylesterase activity
OIO45_14765	COG0473	3-isopropylmalate dehydrogenase activity
OIO45_14770	COG0583	DNA-binding transcription factor activity
OIO45_14800	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO45_14825	COG0564	pseudouridine synthase activity
OIO45_14835	COG0358	DNA primase activity
OIO45_14850	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OIO45_14870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO45_14900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIO45_14910	COG0351	phosphomethylpyrimidine kinase
OIO45_14910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO45_14910	COG0352	thiamine-phosphate diphosphorylase activity
OIO45_14915	COG1652	LysM domain
OIO45_14940	COG1399	metal-binding, possibly nucleic acid-binding protein
OIO45_14945	COG3101	peptidyl-lysine hydroxylation
OIO45_14950	COG0009	L-threonylcarbamoyladenylate synthase
OIO45_14955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIO45_14960	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIO45_14975	COG4106	trans-aconitate 2-methyltransferase activity
OIO45_14990	COG0596	Alpha beta hydrolase
OIO45_14990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO45_14990	COG2226	methyltransferase
OIO45_14995	COG1877	trehalose-phosphatase activity
OIO45_15000	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OIO45_15005	COG2223	nitrite transmembrane transporter activity
OIO45_15025	COG1196	nuclear chromosome segregation
OIO45_15035	COG0730	response to heat
OIO45_15050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIO45_15060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO45_15110	COG0489	protein tyrosine kinase activity
OIO45_15120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO45_15120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO45_15150	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO45_15155	COG2081	HI0933 family
OIO45_15165	COG0668	transmembrane transport
OIO45_15185	COG0583	DNA-binding transcription factor activity
OIO45_15210	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIO45_15215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO45_15245	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIO45_15285	COG0745	RESPONSE REGULATOR receiver
OIO45_15305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO45_15310	COG0697	spore germination
OIO45_15345	COG0477	Major facilitator Superfamily
OIO45_15355	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_15375	COG0384	phenazine biosynthesis protein PhzF
OIO45_15420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO45_15435	COG0583	DNA-binding transcription factor activity
OIO45_15445	COG0583	DNA-binding transcription factor activity
OIO45_15460	COG0583	DNA-binding transcription factor activity
OIO45_15465	COG1053	succinate dehydrogenase
OIO45_15475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO45_15480	COG2814	Major facilitator Superfamily
OIO45_15485	COG1960	acyl-CoA dehydrogenase activity
OIO45_15490	COG0583	DNA-binding transcription factor activity
OIO45_15495	COG1063	alcohol dehydrogenase
OIO45_15525	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIO45_15530	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIO45_15535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO45_15555	COG2132	Multicopper oxidase
OIO45_15565	COG0561	phosphatase activity
OIO45_15570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIO45_15580	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO45_15595	COG1214	PFAM Peptidase M22, glycoprotease
OIO45_15665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIO45_15670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIO45_15675	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIO45_15735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO45_15745	COG1846	Transcriptional regulator
OIO45_15750	COG1764	response to oxidative stress
OIO45_15790	COG0037	tRNA processing
OIO45_15800	COG0248	Ppx GppA phosphatase
OIO45_15830	COG0072	phenylalanine-tRNA ligase activity
OIO45_15875	COG1238	metal cluster binding
OIO45_15880	COG0625	glutathione transferase activity
OIO45_15895	COG0318	PFAM AMP-dependent synthetase and ligase
OIO45_15900	COG3028	Belongs to the UPF0307 family
OIO45_15905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO45_15925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OIO45_15930	COG0617	tRNA 3'-terminal CCA addition
OIO45_15935	COG1555	photosystem II stabilization
OIO45_15940	COG3956	TIGRFAM MazG family protein
OIO45_15950	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO45_15970	COG0784	Response regulator, receiver
OIO45_15970	COG5002	protein histidine kinase activity
OIO45_15970	COG2205	protein histidine kinase activity
OIO45_15975	COG1024	Enoyl-CoA hydratase
OIO45_15980	COG2084	Dehydrogenase
OIO45_15985	COG3622	Belongs to the hyi family
OIO45_16020	COG0697	spore germination
OIO45_16030	COG2814	Major facilitator Superfamily
OIO45_16040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO45_16110	COG4774	siderophore transport
OIO45_16125	COG1271	oxidase subunit
OIO45_16130	COG1294	oxidase, subunit
OIO45_16200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO45_16210	COG0583	DNA-binding transcription factor activity
OIO45_16220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OIO45_16230	COG0084	hydrolase, TatD family'
OIO45_16245	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIO45_16275	COG0440	acetolactate synthase activity
OIO45_16280	COG0028	Belongs to the TPP enzyme family
OIO45_16305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO45_16310	COG1136	(ABC) transporter
OIO45_16310	COG0577	efflux transmembrane transporter activity
OIO45_16315	COG1538	Outer membrane efflux protein
OIO45_16330	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIO45_16335	COG1162	GTPase activity
OIO45_16345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OIO45_16385	COG1426	Protein conserved in bacteria
OIO45_16420	COG0793	Belongs to the peptidase S41A family
OIO45_16435	COG2267	carboxylic ester hydrolase activity
OIO45_16445	COG1012	belongs to the aldehyde dehydrogenase family
OIO45_16450	COG3265	gluconokinase activity
OIO45_16460	COG0800	Aldolase
OIO45_16470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIO45_16475	COG0280	phosphate acetyltransferase
OIO45_16475	COG0857	belongs to the CobB CobQ family
OIO45_16480	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO45_16480	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO45_16500	COG0740	serine-type endopeptidase activity
OIO45_16510	COG4774	siderophore transport
OIO45_16520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO45_16530	COG2813	Specifically methylates the guanine in position
OIO45_16530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO45_16630	COG0788	formyltetrahydrofolate deformylase activity
OIO45_16655	COG4651	solute:proton antiporter activity
OIO45_16655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO45_16675	COG0724	RNA recognition motif
OIO45_16680	COG0210	DNA helicase
OIO45_16705	COG1733	regulation of RNA biosynthetic process
OIO45_16715	COG2900	Belongs to the SlyX family
OIO45_16720	COG0488	(ABC) transporter
OIO45_16725	COG1280	lysine exporter protein (LysE YggA)
OIO45_16730	COG1560	Kdo2-lipid A biosynthetic process
OIO45_16740	COG1301	dicarboxylic acid transport
OIO45_16795	COG0473	3-isopropylmalate dehydrogenase activity
OIO45_16850	COG0583	DNA-binding transcription factor activity
OIO45_16860	COG0625	glutathione transferase activity
OIO45_16865	COG2378	regulation of single-species biofilm formation
OIO45_16870	COG0546	phosphoglycolate phosphatase activity
OIO45_16880	COG1530	ribonuclease E activity
OIO45_16885	COG0318	PFAM AMP-dependent synthetase and ligase
OIO45_16900	COG0583	DNA-binding transcription factor activity
OIO45_16905	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_16910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIO45_16920	COG0534	Mate efflux family protein
OIO45_16935	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OIO45_16960	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO45_16960	COG0493	'glutamate synthase
OIO45_16970	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OIO45_16975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO45_16990	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO45_17000	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OIO45_17000	COG0644	oxidoreductase
OIO45_17010	COG0425	Belongs to the sulfur carrier protein TusA family
OIO45_17015	COG4535	Mg2 and Co2 transporter CorC
OIO45_17025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO45_17045	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIO45_17050	COG0475	glutathione-regulated potassium exporter activity
OIO45_17050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO45_17065	COG0484	heat shock protein binding
OIO45_17070	COG0789	Transcriptional regulator
OIO45_17075	COG0598	Magnesium transport protein CorA
OIO45_17090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO45_17095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO45_17100	COG1074	ATP-dependent DNA helicase activity
OIO45_17105	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OIO45_17125	COG2226	methyltransferase
OIO45_17145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIO45_17160	COG2111	Na H antiporter
OIO45_17160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO45_17165	COG1006	Multisubunit Na H antiporter MnhC subunit
OIO45_17170	COG0651	ATP synthesis coupled electron transport
OIO45_17175	COG1863	multisubunit Na H antiporter MnhE subunit
OIO45_17180	COG2212	antiporter activity
OIO45_17185	COG1320	monovalent cation:proton antiporter activity
OIO45_17200	COG0195	Participates in both transcription termination and antitermination
OIO45_17250	COG0237	dephospho-CoA kinase activity
OIO45_17260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO45_17275	COG0497	DNA recombination
OIO45_17285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIO45_17315	COG2169	Transcriptional regulator
OIO45_17315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO45_17320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIO45_17380	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIO45_17395	COG0326	Molecular chaperone. Has ATPase activity
OIO45_17410	COG2056	Na+-H+ antiporter family
OIO45_17510	COG0546	phosphoglycolate phosphatase activity
OIO45_17515	COG1716	ATPase activity
OIO45_17560	COG0181	hydroxymethylbilane synthase activity
OIO45_17570	COG3275	phosphorelay sensor kinase activity
OIO45_17590	COG1538	Outer membrane efflux protein
OIO45_17595	COG0697	spore germination
OIO45_17640	COG1061	Type III restriction enzyme res subunit
OIO45_17645	COG1002	Type II restriction enzyme, methylase subunits
OIO45_17655	COG0659	secondary active sulfate transmembrane transporter activity
OIO45_17660	COG0589	response to stress
OIO45_17705	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO45_17710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OIO45_17715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO45_17720	COG0772	Belongs to the SEDS family
OIO45_17745	COG4974	Belongs to the 'phage' integrase family
OIO45_17750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO45_17760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIO45_17770	COG2197	response regulator
OIO45_17785	COG0793	Belongs to the peptidase S41A family
OIO45_17790	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIO45_17795	COG0795	lipopolysaccharide-transporting ATPase activity
OIO45_17835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO45_17835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO45_17845	COG0004	ammonium transporteR
OIO45_17850	COG0347	Belongs to the P(II) protein family
OIO45_17885	COG1061	Type III restriction enzyme res subunit
OIO45_17890	COG1002	Type II restriction enzyme, methylase subunits
OIO45_17905	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIO45_17920	COG0318	PFAM AMP-dependent synthetase and ligase
OIO45_17930	COG0477	Major facilitator Superfamily
OIO45_17935	COG2860	membrane
OIO45_17945	COG1253	flavin adenine dinucleotide binding
OIO45_17955	COG0477	Major facilitator Superfamily
OIO45_17960	COG3757	hydrolase, family 25
OIO45_17965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO45_18005	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIO45_18015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIO45_18085	COG0758	DNA mediated transformation
OIO45_18095	COG0697	spore germination
OIO45_18100	COG1309	transcriptional regulator
OIO45_18115	COG0386	Belongs to the glutathione peroxidase family
OIO45_18180	COG1121	(ABC) transporter
OIO45_18185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIO45_18190	COG1280	lysine exporter protein (LysE YggA)
OIO45_18195	COG2837	iron assimilation
OIO45_18205	COG0281	malic enzyme
OIO45_18250	COG0519	Catalyzes the synthesis of GMP from XMP
OIO45_18250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO45_18255	COG4399	Belongs to the UPF0754 family
OIO45_18260	COG2259	Doxx family
OIO45_18265	COG0586	Pfam SNARE associated Golgi protein
OIO45_18280	COG1192	Involved in chromosome partitioning
OIO45_18290	COG0271	Belongs to the BolA IbaG family
OIO45_18310	COG2267	carboxylic ester hydrolase activity
OIO45_18330	COG3321	synthase
OIO45_18330	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OIO45_18330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIO45_18330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO45_18335	COG1960	acyl-CoA dehydrogenase activity
OIO45_18345	COG2197	response regulator
OIO45_18355	COG3916	Acyl-homoserine-lactone synthase
OIO45_18360	COG0477	Major facilitator Superfamily
OIO45_18365	COG1024	Enoyl-CoA hydratase
OIO45_18370	COG1024	Enoyl-CoA hydratase
OIO45_18375	COG1960	acyl-CoA dehydrogenase activity
OIO45_18380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO45_18400	COG1113	amino acid transport
OIO45_18405	COG1113	amino acid transport
OIO45_18410	COG0251	oxidation-reduction process
OIO45_18450	COG0564	pseudouridine synthase activity
OIO45_18480	COG1051	belongs to the nudix hydrolase family
OIO45_18505	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIO45_18520	COG1802	Transcriptional regulator
OIO45_18530	COG1448	Aminotransferase
OIO45_18535	COG0277	FAD linked oxidase domain protein
OIO45_18545	COG2186	Transcriptional regulator
OIO45_18555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO45_18560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO45_18575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIO45_18585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OIO45_18595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OIO45_18600	COG0438	transferase activity, transferring glycosyl groups
OIO45_18610	COG0438	transferase activity, transferring glycosyl groups
OIO45_18630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OIO45_18660	COG0728	peptidoglycan biosynthetic process
OIO45_18665	COG3023	N-Acetylmuramoyl-L-alanine amidase
OIO45_18700	COG1017	nitric oxide dioxygenase activity
OIO45_18700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO45_18725	COG0546	phosphoglycolate phosphatase activity
OIO45_18730	COG1028	Short-chain dehydrogenase reductase Sdr
OIO45_18750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO45_18755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO45_18760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO45_18765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO45_18770	COG1116	anion transmembrane transporter activity
OIO45_18775	COG1309	transcriptional regulator
OIO45_18780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO45_18790	COG0196	riboflavin kinase activity
OIO45_18795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIO45_18805	COG1047	Peptidyl-prolyl cis-trans
OIO45_18845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIO45_18850	COG0657	acetylesterase activity
OIO45_18870	COG0583	DNA-binding transcription factor activity
OIO45_18900	COG2951	lytic endotransglycosylase activity
OIO45_18905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIO45_18920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIO45_18930	COG0671	phosphoesterase, PA-phosphatase related
OIO45_18935	COG0861	Integral membrane protein TerC family
OIO45_18945	COG0754	glutathionylspermidine amidase activity
OIO45_18955	COG0402	S-adenosylhomocysteine deaminase activity
OIO45_18970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO45_18975	COG1230	cation diffusion facilitator family transporter
OIO45_18990	COG0706	membrane insertase activity
OIO45_19010	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO45_19125	COG4683	PFAM Phage derived protein Gp49-like (DUF891)