locus-tag	class	description
OIO75_00010	COG0592	DNA-directed DNA polymerase activity
OIO75_00020	COG0187	DNA topoisomerase II activity
OIO75_00030	COG0586	Pfam SNARE associated Golgi protein
OIO75_00035	COG0488	(ABC) transporter
OIO75_00060	COG0596	Alpha beta hydrolase
OIO75_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OIO75_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO75_00110	COG1047	Peptidyl-prolyl cis-trans
OIO75_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIO75_00125	COG0196	riboflavin kinase activity
OIO75_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO75_00140	COG1309	transcriptional regulator
OIO75_00145	COG1116	anion transmembrane transporter activity
OIO75_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO75_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO75_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO75_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO75_00185	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_00190	COG0546	phosphoglycolate phosphatase activity
OIO75_00215	COG1017	nitric oxide dioxygenase activity
OIO75_00215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO75_00250	COG3023	N-Acetylmuramoyl-L-alanine amidase
OIO75_00255	COG0728	peptidoglycan biosynthetic process
OIO75_00285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OIO75_00305	COG0438	transferase activity, transferring glycosyl groups
OIO75_00315	COG0438	transferase activity, transferring glycosyl groups
OIO75_00320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OIO75_00330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OIO75_00340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIO75_00355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO75_00360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO75_00370	COG2186	Transcriptional regulator
OIO75_00380	COG0277	FAD linked oxidase domain protein
OIO75_00385	COG1448	Aminotransferase
OIO75_00395	COG1802	Transcriptional regulator
OIO75_00410	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIO75_00435	COG1051	belongs to the nudix hydrolase family
OIO75_00465	COG0564	pseudouridine synthase activity
OIO75_00505	COG0251	oxidation-reduction process
OIO75_00510	COG1113	amino acid transport
OIO75_00515	COG1113	amino acid transport
OIO75_00535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO75_00540	COG1960	acyl-CoA dehydrogenase activity
OIO75_00545	COG1024	Enoyl-CoA hydratase
OIO75_00550	COG1024	Enoyl-CoA hydratase
OIO75_00555	COG0477	Major facilitator Superfamily
OIO75_00560	COG3916	Acyl-homoserine-lactone synthase
OIO75_00570	COG2197	response regulator
OIO75_00580	COG1960	acyl-CoA dehydrogenase activity
OIO75_00585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIO75_00585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OIO75_00585	COG3321	synthase
OIO75_00585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO75_00605	COG2267	carboxylic ester hydrolase activity
OIO75_00625	COG0271	Belongs to the BolA IbaG family
OIO75_00635	COG1192	Involved in chromosome partitioning
OIO75_00650	COG0586	Pfam SNARE associated Golgi protein
OIO75_00655	COG2259	Doxx family
OIO75_00660	COG4399	Belongs to the UPF0754 family
OIO75_00665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO75_00665	COG0519	Catalyzes the synthesis of GMP from XMP
OIO75_00710	COG0281	malic enzyme
OIO75_00720	COG2837	iron assimilation
OIO75_00725	COG1280	lysine exporter protein (LysE YggA)
OIO75_00730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIO75_00735	COG1121	(ABC) transporter
OIO75_00800	COG0386	Belongs to the glutathione peroxidase family
OIO75_00815	COG1309	transcriptional regulator
OIO75_00820	COG0697	spore germination
OIO75_00830	COG0758	DNA mediated transformation
OIO75_00900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIO75_00910	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIO75_00950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO75_00955	COG3757	hydrolase, family 25
OIO75_00960	COG0477	Major facilitator Superfamily
OIO75_00970	COG1253	flavin adenine dinucleotide binding
OIO75_00980	COG2860	membrane
OIO75_00985	COG0477	Major facilitator Superfamily
OIO75_00995	COG0318	PFAM AMP-dependent synthetase and ligase
OIO75_01010	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIO75_01035	COG1061	Type III restriction enzyme res subunit
OIO75_01040	COG1002	Type II restriction enzyme, methylase subunits
OIO75_01050	COG0659	secondary active sulfate transmembrane transporter activity
OIO75_01055	COG0589	response to stress
OIO75_01100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO75_01105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OIO75_01110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO75_01115	COG0772	Belongs to the SEDS family
OIO75_01140	COG4974	Belongs to the 'phage' integrase family
OIO75_01145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO75_01155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIO75_01165	COG2197	response regulator
OIO75_01180	COG0793	Belongs to the peptidase S41A family
OIO75_01185	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIO75_01190	COG0795	lipopolysaccharide-transporting ATPase activity
OIO75_01230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO75_01230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO75_01240	COG0004	ammonium transporteR
OIO75_01245	COG0347	Belongs to the P(II) protein family
OIO75_01270	COG1002	Type II restriction enzyme, methylase subunits
OIO75_01275	COG1061	Type III restriction enzyme res subunit
OIO75_01320	COG0697	spore germination
OIO75_01325	COG1538	Outer membrane efflux protein
OIO75_01345	COG3275	phosphorelay sensor kinase activity
OIO75_01355	COG0181	hydroxymethylbilane synthase activity
OIO75_01400	COG1716	ATPase activity
OIO75_01405	COG0546	phosphoglycolate phosphatase activity
OIO75_01505	COG2056	Na+-H+ antiporter family
OIO75_01520	COG0326	Molecular chaperone. Has ATPase activity
OIO75_01535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIO75_01595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIO75_01600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO75_01600	COG2169	Transcriptional regulator
OIO75_01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIO75_01640	COG0497	DNA recombination
OIO75_01655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO75_01665	COG0237	dephospho-CoA kinase activity
OIO75_01715	COG0195	Participates in both transcription termination and antitermination
OIO75_01730	COG1320	monovalent cation:proton antiporter activity
OIO75_01735	COG2212	antiporter activity
OIO75_01740	COG1863	multisubunit Na H antiporter MnhE subunit
OIO75_01745	COG0651	ATP synthesis coupled electron transport
OIO75_01750	COG1006	Multisubunit Na H antiporter MnhC subunit
OIO75_01755	COG2111	Na H antiporter
OIO75_01755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO75_01770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIO75_01790	COG2226	methyltransferase
OIO75_01810	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OIO75_01815	COG1074	ATP-dependent DNA helicase activity
OIO75_01820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO75_01825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO75_01840	COG0598	Magnesium transport protein CorA
OIO75_01845	COG0789	Transcriptional regulator
OIO75_01850	COG0484	heat shock protein binding
OIO75_01865	COG0475	glutathione-regulated potassium exporter activity
OIO75_01865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO75_01870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIO75_01890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO75_01900	COG4535	Mg2 and Co2 transporter CorC
OIO75_01905	COG0425	Belongs to the sulfur carrier protein TusA family
OIO75_01915	COG0644	oxidoreductase
OIO75_01915	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OIO75_01925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO75_01940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO75_01945	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OIO75_01955	COG0493	'glutamate synthase
OIO75_01955	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO75_01980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OIO75_01995	COG0534	Mate efflux family protein
OIO75_02005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIO75_02010	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_02015	COG0583	DNA-binding transcription factor activity
OIO75_02030	COG0318	PFAM AMP-dependent synthetase and ligase
OIO75_02035	COG1530	ribonuclease E activity
OIO75_02045	COG0546	phosphoglycolate phosphatase activity
OIO75_02050	COG2378	regulation of single-species biofilm formation
OIO75_02055	COG0625	glutathione transferase activity
OIO75_02065	COG0583	DNA-binding transcription factor activity
OIO75_02120	COG0473	3-isopropylmalate dehydrogenase activity
OIO75_02175	COG1301	dicarboxylic acid transport
OIO75_02185	COG1560	Kdo2-lipid A biosynthetic process
OIO75_02190	COG1280	lysine exporter protein (LysE YggA)
OIO75_02195	COG0488	(ABC) transporter
OIO75_02200	COG2900	Belongs to the SlyX family
OIO75_02210	COG1733	regulation of RNA biosynthetic process
OIO75_02235	COG0210	DNA helicase
OIO75_02240	COG0724	RNA recognition motif
OIO75_02260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO75_02260	COG4651	solute:proton antiporter activity
OIO75_02285	COG0788	formyltetrahydrofolate deformylase activity
OIO75_02385	COG2813	Specifically methylates the guanine in position
OIO75_02385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO75_02395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO75_02405	COG4774	siderophore transport
OIO75_02415	COG0740	serine-type endopeptidase activity
OIO75_02435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO75_02435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO75_02440	COG0280	phosphate acetyltransferase
OIO75_02440	COG0857	belongs to the CobB CobQ family
OIO75_02445	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIO75_02455	COG0800	Aldolase
OIO75_02465	COG3265	gluconokinase activity
OIO75_02470	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_02480	COG2267	carboxylic ester hydrolase activity
OIO75_02495	COG0793	Belongs to the peptidase S41A family
OIO75_02530	COG1426	Protein conserved in bacteria
OIO75_02570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OIO75_02580	COG1162	GTPase activity
OIO75_02585	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIO75_02600	COG1538	Outer membrane efflux protein
OIO75_02605	COG0577	efflux transmembrane transporter activity
OIO75_02605	COG1136	(ABC) transporter
OIO75_02610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO75_02635	COG0028	Belongs to the TPP enzyme family
OIO75_02640	COG0440	acetolactate synthase activity
OIO75_02670	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIO75_02685	COG0084	hydrolase, TatD family'
OIO75_02695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OIO75_02705	COG0583	DNA-binding transcription factor activity
OIO75_02715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO75_02785	COG1294	oxidase, subunit
OIO75_02790	COG1271	oxidase subunit
OIO75_02805	COG4774	siderophore transport
OIO75_02875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO75_02885	COG2814	Major facilitator Superfamily
OIO75_02895	COG0697	spore germination
OIO75_02930	COG3622	Belongs to the hyi family
OIO75_02935	COG2084	Dehydrogenase
OIO75_02940	COG1024	Enoyl-CoA hydratase
OIO75_02945	COG5002	protein histidine kinase activity
OIO75_02945	COG0784	Response regulator, receiver
OIO75_02945	COG2205	protein histidine kinase activity
OIO75_02965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO75_02975	COG3956	TIGRFAM MazG family protein
OIO75_02980	COG1555	photosystem II stabilization
OIO75_02985	COG0617	tRNA 3'-terminal CCA addition
OIO75_02990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OIO75_03010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO75_03015	COG3028	Belongs to the UPF0307 family
OIO75_03020	COG0318	PFAM AMP-dependent synthetase and ligase
OIO75_03035	COG0625	glutathione transferase activity
OIO75_03040	COG1238	metal cluster binding
OIO75_03085	COG0072	phenylalanine-tRNA ligase activity
OIO75_03115	COG0248	Ppx GppA phosphatase
OIO75_03125	COG0037	tRNA processing
OIO75_03165	COG1764	response to oxidative stress
OIO75_03170	COG1846	Transcriptional regulator
OIO75_03180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO75_03240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIO75_03245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIO75_03250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIO75_03320	COG1214	PFAM Peptidase M22, glycoprotease
OIO75_03335	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO75_03345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIO75_03350	COG0561	phosphatase activity
OIO75_03360	COG2132	Multicopper oxidase
OIO75_03380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO75_03385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIO75_03390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIO75_03420	COG1063	alcohol dehydrogenase
OIO75_03425	COG0583	DNA-binding transcription factor activity
OIO75_03430	COG1960	acyl-CoA dehydrogenase activity
OIO75_03435	COG2814	Major facilitator Superfamily
OIO75_03440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO75_03450	COG1053	succinate dehydrogenase
OIO75_03455	COG0583	DNA-binding transcription factor activity
OIO75_03470	COG0583	DNA-binding transcription factor activity
OIO75_03480	COG0583	DNA-binding transcription factor activity
OIO75_03495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO75_03540	COG0384	phenazine biosynthesis protein PhzF
OIO75_03560	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_03570	COG0477	Major facilitator Superfamily
OIO75_03605	COG0697	spore germination
OIO75_03610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO75_03630	COG0745	RESPONSE REGULATOR receiver
OIO75_03670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIO75_03700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO75_03705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIO75_03730	COG0583	DNA-binding transcription factor activity
OIO75_03750	COG0668	transmembrane transport
OIO75_03760	COG2081	HI0933 family
OIO75_03765	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO75_03795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO75_03795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO75_03805	COG0489	protein tyrosine kinase activity
OIO75_03855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO75_03865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIO75_03880	COG0730	response to heat
OIO75_03890	COG1196	nuclear chromosome segregation
OIO75_03910	COG2223	nitrite transmembrane transporter activity
OIO75_03915	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OIO75_03920	COG1877	trehalose-phosphatase activity
OIO75_03925	COG0596	Alpha beta hydrolase
OIO75_03925	COG2226	methyltransferase
OIO75_03925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO75_03940	COG4106	trans-aconitate 2-methyltransferase activity
OIO75_03955	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIO75_03960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIO75_03965	COG0009	L-threonylcarbamoyladenylate synthase
OIO75_03970	COG3101	peptidyl-lysine hydroxylation
OIO75_03975	COG1399	metal-binding, possibly nucleic acid-binding protein
OIO75_04000	COG1652	LysM domain
OIO75_04005	COG0351	phosphomethylpyrimidine kinase
OIO75_04005	COG0352	thiamine-phosphate diphosphorylase activity
OIO75_04005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO75_04015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIO75_04045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO75_04065	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OIO75_04080	COG0358	DNA primase activity
OIO75_04090	COG0564	pseudouridine synthase activity
OIO75_04115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO75_04145	COG0583	DNA-binding transcription factor activity
OIO75_04150	COG0473	3-isopropylmalate dehydrogenase activity
OIO75_04160	COG0657	acetylesterase activity
OIO75_04170	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_04190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIO75_04190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO75_04205	COG1981	membrane
OIO75_04250	COG0456	acetyltransferase
OIO75_04260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OIO75_04265	COG0492	ferredoxin-NADP+ reductase activity
OIO75_04270	COG1674	ftsk spoiiie
OIO75_04270	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OIO75_04275	COG1280	lysine exporter protein (LysE YggA)
OIO75_04290	COG2894	cell division
OIO75_04305	COG0204	Acyl-transferase
OIO75_04310	COG2885	chlorophyll binding
OIO75_04315	COG0210	DNA helicase
OIO75_04325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO75_04340	COG0121	glutamine amidotransferase
OIO75_04360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO75_04365	COG0735	belongs to the Fur family
OIO75_04390	COG0420	3'-5' exonuclease activity
OIO75_04410	COG1090	epimerase
OIO75_04425	COG2050	protein possibly involved in aromatic compounds catabolism
OIO75_04435	COG2814	Major facilitator Superfamily
OIO75_04440	COG0405	Gamma-glutamyltransferase
OIO75_04520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO75_04605	COG1484	DNA-dependent DNA replication
OIO75_04825	COG2026	Addiction module toxin, RelE StbE family
OIO75_04865	COG0592	DNA-directed DNA polymerase activity
OIO75_04950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO75_05010	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OIO75_05020	COG0477	Major facilitator Superfamily
OIO75_05025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO75_05035	COG1595	DNA-templated transcription, initiation
OIO75_05090	COG0531	amino acid
OIO75_05095	COG2040	homocysteine
OIO75_05120	COG1309	transcriptional regulator
OIO75_05125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO75_05130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO75_05140	COG1607	acyl-coa hydrolase
OIO75_05150	COG0523	cobalamin synthesis protein
OIO75_05160	COG4681	YaeQ
OIO75_05170	COG0726	polysaccharide deacetylase
OIO75_05170	COG1649	PFAM Uncharacterised BCR, COG1649
OIO75_05175	COG1215	transferase activity, transferring glycosyl groups
OIO75_05185	COG1024	Enoyl-CoA hydratase
OIO75_05200	COG1414	Transcriptional regulator
OIO75_05220	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_05230	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO75_05235	COG2271	Major facilitator Superfamily
OIO75_05245	COG2267	carboxylic ester hydrolase activity
OIO75_05250	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_05265	COG0028	Belongs to the TPP enzyme family
OIO75_05275	COG0477	Major facilitator Superfamily
OIO75_05280	COG0242	peptide deformylase activity
OIO75_05285	COG2066	Belongs to the glutaminase family
OIO75_05290	COG2207	Transcriptional regulator
OIO75_05310	COG0583	DNA-binding transcription factor activity
OIO75_05315	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_05320	COG2271	Major facilitator Superfamily
OIO75_05325	COG3959	Transketolase, thiamine diphosphate binding domain
OIO75_05330	COG3958	Transketolase
OIO75_05340	COG0306	phosphate transporter
OIO75_05365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIO75_05410	COG4181	ATPase activity
OIO75_05415	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OIO75_05445	COG0583	DNA-binding transcription factor activity
OIO75_05455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO75_05460	COG1773	rubredoxin
OIO75_05510	COG2851	Citrate transporter
OIO75_05515	COG1253	flavin adenine dinucleotide binding
OIO75_05555	COG0804	urea catabolic process
OIO75_05565	COG0830	nickel cation binding
OIO75_05580	COG0742	ribosomal rna small subunit methyltransferase
OIO75_05585	COG0768	penicillin binding
OIO75_05610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIO75_05615	COG2878	Part of a membrane complex involved in electron transport
OIO75_05620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO75_05630	COG3384	dioxygenase
OIO75_05650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIO75_05830	COG5410	chromosome segregation
OIO75_05995	COG2194	sulfuric ester hydrolase activity
OIO75_06030	COG0006	proline dipeptidase activity
OIO75_06035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO75_06040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO75_06060	COG1279	arginine transmembrane transporter activity
OIO75_06065	COG0583	DNA-binding transcription factor activity
OIO75_06105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO75_06110	COG0741	lytic transglycosylase activity
OIO75_06110	COG0741	lytic transglycosylase activity
OIO75_06110	COG1388	LysM domain
OIO75_06110	COG1388	LysM domain
OIO75_06120	COG4174	ABC transporter (Permease)
OIO75_06125	COG4239	(ABC) transporter, permease
OIO75_06130	COG4172	Belongs to the ABC transporter superfamily
OIO75_06155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO75_06165	COG2203	Gaf domain
OIO75_06165	COG3706	GGDEF domain
OIO75_06165	COG4251	negative regulation of phosphorylation
OIO75_06165	COG5001	Diguanylate cyclase
OIO75_06175	COG1902	pentaerythritol trinitrate reductase activity
OIO75_06175	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO75_06190	COG4269	membrane
OIO75_06210	COG3209	COG3209 Rhs family protein
OIO75_06250	COG1113	amino acid transport
OIO75_06260	COG0531	amino acid
OIO75_06280	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_06300	COG1113	amino acid transport
OIO75_06345	COG0697	spore germination
OIO75_06350	COG2721	sulfolactate sulfo-lyase activity
OIO75_06355	COG2271	Major facilitator Superfamily
OIO75_06360	COG4948	Mandelate Racemase Muconate Lactonizing
OIO75_06370	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_06375	COG2186	Transcriptional regulator
OIO75_06400	COG1960	acyl-CoA dehydrogenase activity
OIO75_06410	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_06415	COG1024	Enoyl-CoA hydratase
OIO75_06420	COG2814	Major facilitator Superfamily
OIO75_06440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO75_06485	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIO75_06490	COG2072	flavoprotein involved in K transport
OIO75_06495	COG0300	oxidoreductase activity
OIO75_06505	COG1309	transcriptional regulator
OIO75_06510	COG1741	Belongs to the pirin family
OIO75_06525	COG2072	flavoprotein involved in K transport
OIO75_06535	COG2252	PERMEase
OIO75_06540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIO75_06545	COG3038	cytochrome b561
OIO75_06555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIO75_06570	COG0527	aspartate kinase activity
OIO75_06580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIO75_06595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIO75_06610	COG0667	Aldo Keto reductase
OIO75_06625	COG1765	OsmC-like protein
OIO75_06640	COG0542	response to heat
OIO75_06675	COG2885	chlorophyll binding
OIO75_06685	COG0625	glutathione transferase activity
OIO75_06845	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIO75_06865	COG3634	alkyl hydroperoxide reductase activity
OIO75_06875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIO75_06885	COG0450	alkyl hydroperoxide reductase
OIO75_06890	COG1643	Atp-dependent helicase
OIO75_06905	COG2814	Major facilitator Superfamily
OIO75_06910	COG3135	benzoate transporter
OIO75_06915	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_06920	COG0543	2 iron, 2 sulfur cluster binding
OIO75_06920	COG0633	Ferredoxin
OIO75_06930	COG4638	Rieske (2fe-2S)
OIO75_06940	COG0583	DNA-binding transcription factor activity
OIO75_06990	COG1570	exodeoxyribonuclease VII activity
OIO75_07020	COG1280	lysine exporter protein (LysE YggA)
OIO75_07025	COG1278	Cold shock
OIO75_07060	COG2814	Major facilitator Superfamily
OIO75_07100	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OIO75_07100	COG0517	IMP dehydrogenase activity
OIO75_07105	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OIO75_07115	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OIO75_07120	COG1137	ATPase activity
OIO75_07155	COG4122	O-methyltransferase activity
OIO75_07165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OIO75_07180	COG1522	sequence-specific DNA binding
OIO75_07185	COG5006	permease, DMT superfamily
OIO75_07195	COG1560	Kdo2-lipid A biosynthetic process
OIO75_07205	COG0598	Magnesium transport protein CorA
OIO75_07235	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO75_07240	COG1116	anion transmembrane transporter activity
OIO75_07245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO75_07270	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO75_07330	COG1914	H( )-stimulated, divalent metal cation uptake system
OIO75_07350	COG4770	biotin carboxylase activity
OIO75_07355	COG0038	chloride channel
OIO75_07395	COG1309	transcriptional regulator
OIO75_07405	COG1063	alcohol dehydrogenase
OIO75_07420	COG0439	Biotin carboxylase
OIO75_07425	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO75_07430	COG1733	regulation of RNA biosynthetic process
OIO75_07440	COG0864	Transcriptional regulator
OIO75_07450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO75_07455	COG1116	anion transmembrane transporter activity
OIO75_07585	COG0590	tRNA wobble adenosine to inosine editing
OIO75_07590	COG2807	transmembrane transport
OIO75_07605	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OIO75_07615	COG0789	Transcriptional regulator
OIO75_07625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO75_07645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO75_07670	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_07675	COG0531	amino acid
OIO75_07680	COG1760	l-serine dehydratase
OIO75_07685	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_07685	COG2030	dehydratase
OIO75_07690	COG3396	Phenylacetate-CoA oxygenase
OIO75_07695	COG3460	Phenylacetate-CoA oxygenase
OIO75_07700	COG3396	Phenylacetate-CoA oxygenase
OIO75_07705	COG2151	metal-sulfur cluster biosynthetic enzyme
OIO75_07710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO75_07715	COG1024	Enoyl-CoA hydratase
OIO75_07720	COG1024	Enoyl-CoA hydratase
OIO75_07725	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO75_07730	COG0183	Belongs to the thiolase family
OIO75_07735	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OIO75_07740	COG3327	negative regulation of DNA-templated transcription, initiation
OIO75_07750	COG2050	protein possibly involved in aromatic compounds catabolism
OIO75_07760	COG0556	nucleotide-excision repair
OIO75_07795	COG1278	Cold shock
OIO75_07805	COG2207	Transcriptional regulator
OIO75_07890	COG0753	catalase activity
OIO75_07895	COG3038	cytochrome b561
OIO75_07915	COG2267	carboxylic ester hydrolase activity
OIO75_07920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO75_07925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO75_07930	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_07940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO75_07950	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_07955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO75_07960	COG0583	DNA-binding transcription factor activity
OIO75_07970	COG1414	Transcriptional regulator
OIO75_07975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO75_07990	COG1840	ABC-type Fe3 transport system, periplasmic component
OIO75_07995	COG3842	ATPase activity
OIO75_08015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO75_08035	COG0583	DNA-binding transcription factor activity
OIO75_08045	COG4770	biotin carboxylase activity
OIO75_08050	COG1024	Enoyl-CoA hydratase
OIO75_08055	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO75_08060	COG1960	acyl-CoA dehydrogenase activity
OIO75_08065	COG1309	transcriptional regulator
OIO75_08070	COG0318	PFAM AMP-dependent synthetase and ligase
OIO75_08090	COG0583	DNA-binding transcription factor activity
OIO75_08140	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_08160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIO75_08180	COG0784	Response regulator, receiver
OIO75_08180	COG2205	protein histidine kinase activity
OIO75_08200	COG0765	amino acid transport
OIO75_08205	COG0765	amino acid transport
OIO75_08210	COG1126	abc transporter atp-binding protein
OIO75_08215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO75_08220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO75_08235	COG1280	lysine exporter protein (LysE YggA)
OIO75_08245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIO75_08250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO75_08255	COG1045	serine acetyltransferase
OIO75_08265	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_08270	COG0583	DNA-binding transcription factor activity
OIO75_08275	COG0625	glutathione transferase activity
OIO75_08280	COG0625	glutathione transferase activity
OIO75_08285	COG0583	DNA-binding transcription factor activity
OIO75_08295	COG1346	cytolysis
OIO75_08315	COG2814	Major facilitator Superfamily
OIO75_08325	COG0583	DNA-binding transcription factor activity
OIO75_08335	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OIO75_08340	COG3052	prosthetic group binding
OIO75_08360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OIO75_08380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO75_08390	COG1294	oxidase, subunit
OIO75_08395	COG1271	oxidase subunit
OIO75_08415	COG0477	Major facilitator Superfamily
OIO75_08425	COG4521	taurine ABC transporter
OIO75_08445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO75_08450	COG2175	clavaminate synthase activity
OIO75_08460	COG1953	Uracil, thiamine, allantoin
OIO75_08470	COG0583	DNA-binding transcription factor activity
OIO75_08480	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIO75_08495	COG0640	Transcriptional regulator
OIO75_08500	COG0798	PFAM Bile acid sodium symporter
OIO75_08505	COG0583	DNA-binding transcription factor activity
OIO75_08520	COG3634	alkyl hydroperoxide reductase activity
OIO75_08555	COG1301	dicarboxylic acid transport
OIO75_08560	COG0436	Aminotransferase
OIO75_08570	COG0386	Belongs to the glutathione peroxidase family
OIO75_08610	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO75_08635	COG0012	GTP binding
OIO75_08640	COG2011	ABC-type metal ion transport system permease component
OIO75_08645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO75_08655	COG1464	Belongs to the NlpA lipoprotein family
OIO75_08685	COG0765	amino acid transport
OIO75_08690	COG0765	amino acid transport
OIO75_08695	COG1126	abc transporter atp-binding protein
OIO75_08705	COG1522	sequence-specific DNA binding
OIO75_08720	COG1309	transcriptional regulator
OIO75_08740	COG0583	DNA-binding transcription factor activity
OIO75_08750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO75_08760	COG0697	spore germination
OIO75_08785	COG3121	Chaperone
OIO75_08790	COG3539	Fimbrial protein
OIO75_08815	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIO75_08815	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIO75_08860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIO75_08870	COG2353	YceI-like domain
OIO75_08880	COG3698	Phosphodiester glycosidase
OIO75_08895	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIO75_08900	COG0506	proline dehydrogenase activity
OIO75_08900	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO75_08900	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO75_08910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO75_08915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIO75_08935	COG1132	(ABC) transporter
OIO75_08940	COG3122	Protein conserved in bacteria
OIO75_08945	COG3619	membrane
OIO75_08955	COG0640	Transcriptional regulator
OIO75_08965	COG2850	peptidyl-arginine hydroxylation
OIO75_08970	COG0424	maF-like protein
OIO75_08990	COG0191	fructose-bisphosphate aldolase activity
OIO75_08995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO75_09010	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIO75_09020	COG1192	Involved in chromosome partitioning
OIO75_09025	COG1475	DNA binding
OIO75_09030	COG0811	peptide transport
OIO75_09040	COG1132	(ABC) transporter
OIO75_09045	COG1663	tetraacyldisaccharide 4'-kinase activity
OIO75_09065	COG0084	hydrolase, TatD family'
OIO75_09130	COG0776	regulation of translation
OIO75_09160	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OIO75_09165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIO75_09200	COG4166	transmembrane transport
OIO75_09210	COG0339	signal peptide processing
OIO75_09220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIO75_09255	COG0702	epimerase
OIO75_09260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO75_09280	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO75_09310	COG0316	Belongs to the HesB IscA family
OIO75_09315	COG0822	iron-sulfur transferase activity
OIO75_09340	COG0776	regulation of translation
OIO75_09345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO75_09350	COG2207	Transcriptional regulator
OIO75_09355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO75_09360	COG1960	acyl-CoA dehydrogenase activity
OIO75_09365	COG1960	acyl-CoA dehydrogenase activity
OIO75_09380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIO75_09395	COG2814	Major facilitator Superfamily
OIO75_09400	COG4264	IucA IucC family
OIO75_09405	COG4264	IucA IucC family
OIO75_09415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO75_09445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO75_09460	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIO75_09465	COG0406	alpha-ribazole phosphatase activity
OIO75_09480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO75_09485	COG0730	response to heat
OIO75_09510	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO75_09525	COG1131	(ABC) transporter
OIO75_09530	COG0842	Transport permease protein
OIO75_09535	COG0842	Transport permease protein
OIO75_09590	COG2226	methyltransferase
OIO75_09615	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIO75_09650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO75_09660	COG0133	tryptophan synthase activity
OIO75_09675	COG3706	GGDEF domain
OIO75_09690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO75_09695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OIO75_09700	COG0022	dehydrogenase e1 component
OIO75_09705	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO75_09710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO75_09720	COG1063	alcohol dehydrogenase
OIO75_09725	COG3781	membrane
OIO75_09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO75_09735	COG3453	Protein conserved in bacteria
OIO75_09750	COG0730	response to heat
OIO75_09765	COG2207	Transcriptional regulator
OIO75_09765	COG3708	Transcriptional regulator
OIO75_09770	COG1733	regulation of RNA biosynthetic process
OIO75_09775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIO75_09785	COG2188	Transcriptional regulator
OIO75_09800	COG4521	taurine ABC transporter
OIO75_09805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO75_09825	COG0477	Major facilitator Superfamily
OIO75_09835	COG1027	Aspartate ammonia-lyase
OIO75_09855	COG0583	DNA-binding transcription factor activity
OIO75_09860	COG0583	DNA-binding transcription factor activity
OIO75_09865	COG0183	Belongs to the thiolase family
OIO75_09870	COG2031	fatty acid transporter
OIO75_09885	COG0583	DNA-binding transcription factor activity
OIO75_09895	COG2610	gluconate transmembrane transporter activity
OIO75_09900	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_09905	COG2207	Transcriptional regulator
OIO75_09920	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_09930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO75_09945	COG0543	2 iron, 2 sulfur cluster binding
OIO75_09945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO75_09950	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO75_09955	COG4638	Rieske (2fe-2S)
OIO75_09965	COG0725	ABC transporter, periplasmic molybdate-binding protein
OIO75_09970	COG4149	molybdate abc transporter
OIO75_09975	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OIO75_09980	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_09985	COG3433	isochorismatase activity
OIO75_09985	COG1535	isochorismatase
OIO75_10045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO75_10075	COG0753	catalase activity
OIO75_10085	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO75_10110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO75_10115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO75_10120	COG0745	RESPONSE REGULATOR receiver
OIO75_10125	COG2205	protein histidine kinase activity
OIO75_10135	COG2207	Transcriptional regulator
OIO75_10145	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_10175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO75_10175	COG3320	Male sterility
OIO75_10180	COG2814	Major facilitator Superfamily
OIO75_10205	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OIO75_10255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO75_10275	COG1120	ATPase activity
OIO75_10280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO75_10290	COG1064	alcohol dehydrogenase
OIO75_10305	COG2207	Transcriptional regulator
OIO75_10310	COG2084	Dehydrogenase
OIO75_10320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO75_10325	COG0583	DNA-binding transcription factor activity
OIO75_10335	COG0129	dihydroxy-acid dehydratase activity
OIO75_10340	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_10345	COG1846	Transcriptional regulator
OIO75_10350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO75_10355	COG1960	acyl-CoA dehydrogenase activity
OIO75_10360	COG0477	Major facilitator Superfamily
OIO75_10375	COG3971	2-oxopent-4-enoate hydratase activity
OIO75_10385	COG3384	dioxygenase
OIO75_10390	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_10400	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO75_10410	COG2814	Major facilitator Superfamily
OIO75_10415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO75_10430	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_10450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO75_10470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO75_10505	COG0583	DNA-binding transcription factor activity
OIO75_10520	COG2188	Transcriptional regulator
OIO75_10575	COG1473	amidohydrolase
OIO75_10585	COG0475	glutathione-regulated potassium exporter activity
OIO75_10585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO75_10595	COG0583	DNA-binding transcription factor activity
OIO75_10600	COG1335	isochorismatase
OIO75_10610	COG1309	transcriptional regulator
OIO75_10645	COG1902	pentaerythritol trinitrate reductase activity
OIO75_10645	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO75_10650	COG1846	Transcriptional regulator
OIO75_10675	COG0753	catalase activity
OIO75_10690	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_10705	COG3162	membrane
OIO75_10715	COG3829	transcription factor binding
OIO75_10720	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_10725	COG1960	acyl-CoA dehydrogenase activity
OIO75_10740	COG3231	kanamycin kinase activity
OIO75_10745	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_10765	COG2186	Transcriptional regulator
OIO75_10775	COG0583	DNA-binding transcription factor activity
OIO75_10780	COG4948	Mandelate Racemase Muconate Lactonizing
OIO75_10785	COG4829	muconolactone delta-isomerase
OIO75_10795	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO75_10800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO75_10805	COG0183	Belongs to the thiolase family
OIO75_10810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO75_10820	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_10830	COG3733	amine oxidase
OIO75_10840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO75_10850	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_10860	COG4638	Rieske (2fe-2S)
OIO75_10880	COG0154	amidase activity
OIO75_10890	COG2814	Major facilitator Superfamily
OIO75_10915	COG1960	acyl-CoA dehydrogenase activity
OIO75_10920	COG0583	DNA-binding transcription factor activity
OIO75_10925	COG1414	Transcriptional regulator
OIO75_10940	COG2391	methyltransferase activity
OIO75_10950	COG4993	Dehydrogenase
OIO75_10955	COG3659	wide pore channel activity
OIO75_10960	COG3420	alginic acid biosynthetic process
OIO75_10965	COG0710	3-dehydroquinate dehydratase activity
OIO75_10970	COG3485	protocatechuate 3,4-dioxygenase
OIO75_10975	COG3485	protocatechuate 3,4-dioxygenase
OIO75_10980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO75_10985	COG2271	Major facilitator Superfamily
OIO75_10990	COG0596	Alpha beta hydrolase
OIO75_10995	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIO75_11000	COG0183	Belongs to the thiolase family
OIO75_11005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO75_11010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO75_11020	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OIO75_11025	COG2323	membrane
OIO75_11070	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO75_11070	COG1902	pentaerythritol trinitrate reductase activity
OIO75_11085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO75_11095	COG0542	response to heat
OIO75_11100	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIO75_11130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO75_11135	COG0569	domain protein
OIO75_11140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIO75_11155	COG4774	siderophore transport
OIO75_11160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIO75_11170	COG1585	Membrane protein implicated in regulation of membrane protease activity
OIO75_11185	COG1294	oxidase, subunit
OIO75_11190	COG4890	Cyd operon protein YbgT
OIO75_11200	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OIO75_11210	COG0552	protein localization to endoplasmic reticulum
OIO75_11235	COG0517	IMP dehydrogenase activity
OIO75_11235	COG0516	GMP reductase activity
OIO75_11240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO75_11245	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OIO75_11255	COG0583	DNA-binding transcription factor activity
OIO75_11260	COG0024	Methionine aminopeptidase
OIO75_11290	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO75_11290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIO75_11295	COG1105	Belongs to the carbohydrate kinase PfkB family
OIO75_11300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO75_11300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO75_11300	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIO75_11320	COG3300	MHYT domain
OIO75_11320	COG5001	Diguanylate cyclase
OIO75_11335	COG2135	peptidase activity
OIO75_11340	COG0659	secondary active sulfate transmembrane transporter activity
OIO75_11360	COG1113	amino acid transport
OIO75_11370	COG1522	sequence-specific DNA binding
OIO75_11395	COG1011	Hydrolase
OIO75_11400	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OIO75_11410	COG2137	regulation of response to DNA damage stimulus
OIO75_11425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO75_11445	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO75_11460	COG0575	Belongs to the CDS family
OIO75_11465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIO75_11485	COG3852	Histidine kinase
OIO75_11490	COG2204	response regulator
OIO75_11545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO75_11550	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OIO75_11570	COG0697	spore germination
OIO75_11575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO75_11590	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIO75_11590	COG0315	cyclic pyranopterin monophosphate synthase activity
OIO75_11610	COG0243	molybdopterin cofactor binding
OIO75_11620	COG0243	molybdopterin cofactor binding
OIO75_11625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO75_11630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO75_11630	COG2146	nitrite reductase [NAD(P)H] activity
OIO75_11640	COG0745	RESPONSE REGULATOR receiver
OIO75_11645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO75_11645	COG1116	anion transmembrane transporter activity
OIO75_11665	COG0511	ligase activity, forming carbon-carbon bonds
OIO75_11680	COG2814	Major facilitator Superfamily
OIO75_11700	COG0069	glutamate synthase activity
OIO75_11720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIO75_11730	COG1454	alcohol dehydrogenase
OIO75_11735	COG0824	Thioesterase
OIO75_11750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIO75_11765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO75_11770	COG2030	dehydratase
OIO75_11780	COG0183	Belongs to the thiolase family
OIO75_11790	COG0583	DNA-binding transcription factor activity
OIO75_11795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIO75_11805	COG1522	sequence-specific DNA binding
OIO75_11810	COG3135	benzoate transporter
OIO75_11820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIO75_11845	COG0589	response to stress
OIO75_11850	COG0488	(ABC) transporter
OIO75_11870	COG4773	Receptor
OIO75_11900	COG0668	transmembrane transport
OIO75_11910	COG1309	transcriptional regulator
OIO75_11930	COG1605	Chorismate mutase
OIO75_11950	COG0308	aminopeptidase N
OIO75_11970	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OIO75_11980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO75_11985	COG1454	alcohol dehydrogenase
OIO75_12005	COG0531	amino acid
OIO75_12010	COG4303	Ethanolamine ammonia lyase large subunit
OIO75_12015	COG4302	ethanolamine ammonia-lyase activity
OIO75_12020	COG0519	Catalyzes the synthesis of GMP from XMP
OIO75_12020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO75_12025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO75_12050	COG0697	spore germination
OIO75_12055	COG1923	regulation of RNA biosynthetic process
OIO75_12065	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIO75_12070	COG0802	atpase or kinase
OIO75_12090	COG1187	pseudouridine synthase activity
OIO75_12105	COG0583	DNA-binding transcription factor activity
OIO75_12120	COG2814	Major facilitator Superfamily
OIO75_12125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO75_12150	COG0729	surface antigen
OIO75_12170	COG0174	glutamine synthetase
OIO75_12175	COG0745	RESPONSE REGULATOR receiver
OIO75_12190	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIO75_12195	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIO75_12205	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OIO75_12220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO75_12225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO75_12230	COG1960	acyl-CoA dehydrogenase activity
OIO75_12245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO75_12250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO75_12270	COG0583	DNA-binding transcription factor activity
OIO75_12285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO75_12295	COG3658	cytochrome
OIO75_12300	COG1215	transferase activity, transferring glycosyl groups
OIO75_12305	COG1649	PFAM Uncharacterised BCR, COG1649
OIO75_12305	COG0726	polysaccharide deacetylase
OIO75_12330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIO75_12335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIO75_12345	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OIO75_12370	COG0305	Participates in initiation and elongation during chromosome replication
OIO75_12375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIO75_12385	COG1305	Transglutaminase-like
OIO75_12395	COG2308	Evidence 4 Homologs of previously reported genes of
OIO75_12425	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OIO75_12430	COG0138	bifunctional purine biosynthesis protein purh
OIO75_12435	COG0151	Belongs to the GarS family
OIO75_12440	COG1464	Belongs to the NlpA lipoprotein family
OIO75_12445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO75_12450	COG2011	ABC-type metal ion transport system permease component
OIO75_12455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO75_12465	COG1301	dicarboxylic acid transport
OIO75_12495	COG1794	racemase activity, acting on amino acids and derivatives
OIO75_12505	COG3008	intermembrane lipid transfer
OIO75_12505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIO75_12510	COG2995	paraquat-inducible protein a
OIO75_12540	COG0477	Major facilitator Superfamily
OIO75_12550	COG2186	Transcriptional regulator
OIO75_12560	COG0786	glutamate:sodium symporter activity
OIO75_12565	COG3243	poly(R)-hydroxyalkanoic acid synthase
OIO75_12590	COG3111	PFAM Bacterial OB fold (BOF) protein
OIO75_12660	COG2815	serine threonine protein kinase
OIO75_12660	COG0515	serine threonine protein kinase
OIO75_12690	COG1610	YqeY-like protein
OIO75_12695	COG4783	chaperone-mediated protein folding
OIO75_12720	COG1286	toxin biosynthetic process
OIO75_12750	COG0778	Nitroreductase
OIO75_12760	COG0513	Belongs to the DEAD box helicase family
OIO75_12785	COG2363	Small membrane protein
OIO75_12815	COG4650	regulator
OIO75_12820	COG1234	tRNA 3'-trailer cleavage
OIO75_12825	COG1690	Belongs to the RtcB family
OIO75_12845	COG2195	Cleaves the N-terminal amino acid of tripeptides
OIO75_12855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIO75_12865	COG2819	hydrolase of the alpha beta superfamily
OIO75_12870	COG1960	acyl-CoA dehydrogenase activity
OIO75_12875	COG1301	dicarboxylic acid transport
OIO75_12885	COG3139	Protein of unknown function (DUF1315)
OIO75_12890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIO75_12895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIO75_12905	COG0494	nUDIX hydrolase
OIO75_12915	COG0642	Histidine kinase
OIO75_12930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OIO75_12940	COG1720	tRNA m6t6A37 methyltransferase activity
OIO75_12955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO75_12960	COG0826	peptidase U32
OIO75_12965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO75_12975	COG4598	ABC transporter
OIO75_12980	COG4160	amino acid transport
OIO75_12985	COG4215	(ABC) transporter
OIO75_13000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO75_13045	COG1131	(ABC) transporter
OIO75_13050	COG0842	Transport permease protein
OIO75_13065	COG0772	Belongs to the SEDS family
OIO75_13070	COG2951	lytic endotransglycosylase activity
OIO75_13095	COG2207	Transcriptional regulator
OIO75_13110	COG0052	Belongs to the universal ribosomal protein uS2 family
OIO75_13115	COG0024	Methionine aminopeptidase
OIO75_13135	COG2223	nitrite transmembrane transporter activity
OIO75_13145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO75_13150	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO75_13155	COG1960	acyl-CoA dehydrogenase activity
OIO75_13170	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIO75_13175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIO75_13180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO75_13200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO75_13205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIO75_13210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIO75_13245	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OIO75_13255	COG0174	glutamine synthetase
OIO75_13270	COG0512	Glutamine amidotransferase of anthranilate synthase
OIO75_13275	COG0308	aminopeptidase N
OIO75_13305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIO75_13315	COG0302	gtp cyclohydrolase
OIO75_13335	COG3739	integral membrane protein
OIO75_13355	COG2977	Belongs to the P-Pant transferase superfamily
OIO75_13360	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OIO75_13365	COG1132	(ABC) transporter
OIO75_13370	COG1132	(ABC) transporter
OIO75_13385	COG1535	isochorismatase
OIO75_13385	COG3433	isochorismatase activity
OIO75_13390	COG1021	2,3-dihydroxybenzoate-AMP ligase
OIO75_13395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO75_13405	COG4774	siderophore transport
OIO75_13410	COG4607	ABC-type enterochelin transport system periplasmic component
OIO75_13415	COG4604	ABC transporter, ATP-binding protein
OIO75_13420	COG4605	iron ion homeostasis
OIO75_13425	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO75_13435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO75_13450	COG2964	Protein conserved in bacteria
OIO75_13460	COG1741	Belongs to the pirin family
OIO75_13490	COG2130	NADP-dependent
OIO75_13500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO75_13510	COG0596	Alpha beta hydrolase
OIO75_13525	COG0583	DNA-binding transcription factor activity
OIO75_13530	COG1335	isochorismatase
OIO75_13570	COG2879	small protein
OIO75_13575	COG1966	Carbon starvation protein
OIO75_13595	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OIO75_13620	COG1067	ATP-dependent peptidase activity
OIO75_13625	COG0583	DNA-binding transcription factor activity
OIO75_13650	COG1686	Belongs to the peptidase S11 family
OIO75_13655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OIO75_13690	COG0616	signal peptide processing
OIO75_13695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIO75_13705	COG0573	inorganic phosphate transmembrane transporter activity
OIO75_13710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIO75_13715	COG1113	amino acid transport
OIO75_13720	COG3961	Belongs to the TPP enzyme family
OIO75_13725	COG1522	sequence-specific DNA binding
OIO75_13735	COG0076	glutamate decarboxylase activity
OIO75_13740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO75_13750	COG1309	transcriptional regulator
OIO75_13765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO75_13800	COG0352	thiamine-phosphate diphosphorylase activity
OIO75_13825	COG0612	Peptidase, M16
OIO75_13835	COG1823	symporter activity
OIO75_13840	COG0583	DNA-binding transcription factor activity
OIO75_13845	COG0477	Major facilitator Superfamily
OIO75_13870	COG0582	viral genome integration into host DNA
OIO75_14005	COG4695	Portal protein
OIO75_14200	COG1187	pseudouridine synthase activity
OIO75_14215	COG1686	Belongs to the peptidase S11 family
OIO75_14220	COG1252	NADH dehydrogenase
OIO75_14235	COG2070	2-Nitropropane dioxygenase
OIO75_14290	COG0556	nucleotide-excision repair
OIO75_14310	COG0436	Aminotransferase
OIO75_14320	COG0443	Heat shock 70 kDa protein
OIO75_14350	COG4221	oxidoreductase activity
OIO75_14360	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OIO75_14365	COG1381	Involved in DNA repair and RecF pathway recombination
OIO75_14375	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIO75_14390	COG0681	Belongs to the peptidase S26 family
OIO75_14400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIO75_14410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO75_14430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIO75_14435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIO75_14440	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OIO75_14450	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIO75_14455	COG4208	sulfate ABC transporter
OIO75_14460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OIO75_14465	COG0583	DNA-binding transcription factor activity
OIO75_14470	COG4625	pathogenesis
OIO75_14485	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OIO75_14500	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OIO75_14510	COG1051	belongs to the nudix hydrolase family
OIO75_14510	COG1056	cytidyltransferase-related domain
OIO75_14515	COG1024	Enoyl-CoA hydratase
OIO75_14530	COG2814	Major facilitator Superfamily
OIO75_14535	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIO75_14535	COG0047	phosphoribosylformylglycinamidine synthase activity
OIO75_14555	COG1473	amidohydrolase
OIO75_14560	COG0824	Thioesterase
OIO75_14580	COG0823	Involved in the tonB-independent uptake of proteins
OIO75_14600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO75_14635	COG0628	permease
OIO75_14645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIO75_14650	COG0596	Alpha beta hydrolase
OIO75_14655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIO75_14655	COG0616	signal peptide processing
OIO75_14665	COG2333	competence protein COMEC
OIO75_14665	COG0658	competence protein
OIO75_14670	COG1136	(ABC) transporter
OIO75_14675	COG4591	ABC-type transport system involved in lipoprotein release permease component
OIO75_14710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO75_14730	COG0463	Glycosyl transferase, family 2
OIO75_14760	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO75_14765	COG1280	lysine exporter protein (LysE YggA)
OIO75_14770	COG2267	carboxylic ester hydrolase activity
OIO75_14780	COG0019	diaminopimelate decarboxylase activity
OIO75_14790	COG1113	amino acid transport
OIO75_14805	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OIO75_14815	COG3339	Conserved Protein
OIO75_14820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIO75_14825	COG0243	molybdopterin cofactor binding
OIO75_14830	COG1929	Belongs to the glycerate kinase type-1 family
OIO75_14845	COG0778	Nitroreductase
OIO75_14870	COG3811	Belongs to the UPF0386 family
OIO75_14895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO75_14910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIO75_14930	COG0741	lytic transglycosylase activity
OIO75_14950	COG0584	glycerophosphoryl diester phosphodiesterase
OIO75_14955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO75_14980	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO75_14985	COG1597	lipid kinase activity
OIO75_15000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIO75_15005	COG0477	Major facilitator Superfamily
OIO75_15055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIO75_15060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO75_15085	COG0505	Belongs to the CarA family
OIO75_15105	COG0589	response to stress
OIO75_15120	COG2843	Capsule synthesis protein
OIO75_15140	COG2321	neutral zinc metallopeptidase
OIO75_15145	COG2354	Protein conserved in bacteria
OIO75_15165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO75_15190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIO75_15195	COG1053	succinate dehydrogenase
OIO75_15200	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OIO75_15205	COG2009	succinate dehydrogenase
OIO75_15240	COG2921	Belongs to the UPF0250 family
OIO75_15245	COG0321	lipoyl(octanoyl) transferase activity
OIO75_15260	COG0531	amino acid
OIO75_15270	COG1733	regulation of RNA biosynthetic process
OIO75_15275	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIO75_15280	COG1648	precorrin-2 dehydrogenase activity
OIO75_15280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIO75_15295	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OIO75_15330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO75_15340	COG1538	Outer membrane efflux protein
OIO75_15345	COG0393	Putative heavy-metal-binding
OIO75_15350	COG0393	Putative heavy-metal-binding
OIO75_15360	COG1028	Short-chain dehydrogenase reductase Sdr
OIO75_15370	COG0525	valine-tRNA ligase activity
OIO75_15390	COG0583	DNA-binding transcription factor activity
OIO75_15395	COG0004	ammonium transporteR
OIO75_15410	COG0642	Histidine kinase
OIO75_15415	COG0745	RESPONSE REGULATOR receiver
OIO75_15420	COG2194	sulfuric ester hydrolase activity
OIO75_15440	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO75_15455	COG2315	Protein conserved in bacteria
OIO75_15460	COG0142	geranyltranstransferase activity
OIO75_15465	COG2828	Protein conserved in bacteria
OIO75_15470	COG1113	amino acid transport
OIO75_15515	COG2207	Transcriptional regulator
OIO75_15540	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO75_15550	COG0560	Phosphoserine phosphatase
OIO75_15560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO75_15570	COG1530	ribonuclease E activity
OIO75_15575	COG0424	maF-like protein
OIO75_15580	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OIO75_15585	COG1792	Involved in formation and maintenance of cell shape
OIO75_15590	COG1077	Cell shape determining protein MreB Mrl
OIO75_15595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO75_15605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO75_15630	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OIO75_15635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO75_15640	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO75_15645	COG1115	amino acid carrier protein
OIO75_15665	COG2814	Major facilitator Superfamily
OIO75_15670	COG1289	transmembrane transporter activity
OIO75_15680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OIO75_15730	COG1376	ErfK ybiS ycfS ynhG family protein
OIO75_15735	COG2832	Protein of unknown function (DUF454)
OIO75_15745	COG5510	response to toxic substance
OIO75_15770	COG0840	transmembrane signaling receptor activity
OIO75_15810	COG3422	double-strand break repair
OIO75_15815	COG2824	Alkylphosphonate utilization operon protein PhnA
OIO75_15820	COG3189	MarR family transcriptional regulator
OIO75_15830	COG0354	folic acid binding
OIO75_15835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO75_15845	COG0679	Auxin Efflux Carrier
OIO75_15850	COG1902	pentaerythritol trinitrate reductase activity
OIO75_15855	COG4772	TonB-dependent receptor
OIO75_15860	COG2094	Belongs to the DNA glycosylase MPG family
OIO75_15885	COG1217	gtp-binding protein TYPA
OIO75_15890	COG2233	PERMEase
OIO75_15900	COG0833	amino acid
OIO75_15905	COG1690	Belongs to the RtcB family
OIO75_15915	COG2885	chlorophyll binding
OIO75_15915	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OIO75_15925	COG0183	Belongs to the thiolase family
OIO75_15945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO75_15965	COG2207	Transcriptional regulator
OIO75_15970	COG0183	Belongs to the thiolase family
OIO75_16000	COG1272	protein, Hemolysin III
OIO75_16005	COG0477	Major facilitator Superfamily
OIO75_16020	COG0450	alkyl hydroperoxide reductase
OIO75_16040	COG0285	dihydrofolate synthase activity
OIO75_16090	COG2096	Adenosyltransferase
OIO75_16095	COG0584	glycerophosphoryl diester phosphodiesterase
OIO75_16110	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OIO75_16115	COG0745	RESPONSE REGULATOR receiver
OIO75_16120	COG2205	protein histidine kinase activity
OIO75_16130	COG1960	acyl-CoA dehydrogenase activity
OIO75_16135	COG1960	acyl-CoA dehydrogenase activity
OIO75_16200	COG0438	transferase activity, transferring glycosyl groups
OIO75_16205	COG0463	Glycosyl transferase, family 2
OIO75_16210	COG0726	polysaccharide deacetylase
OIO75_16230	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIO75_16235	COG2205	protein histidine kinase activity
OIO75_16265	COG1862	Preprotein translocase
OIO75_16275	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIO75_16280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIO75_16290	COG3781	membrane
OIO75_16295	COG0613	PHP domain protein
OIO75_16305	COG2350	Protein conserved in bacteria
OIO75_16335	COG1607	acyl-coa hydrolase
OIO75_16395	COG2199	diguanylate cyclase activity
OIO75_16405	COG1408	metallophosphoesterase
OIO75_16410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO75_16420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIO75_16440	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIO75_16445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIO75_16450	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OIO75_16460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIO75_16470	COG2969	positive regulation of protein catabolic process
OIO75_16490	COG1960	acyl-CoA dehydrogenase activity
OIO75_16495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO75_16510	COG1309	transcriptional regulator
OIO75_16515	COG1960	acyl-CoA dehydrogenase activity
OIO75_16560	COG1183	phosphatidylcholine synthase activity
OIO75_16565	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OIO75_16595	COG0741	lytic transglycosylase activity
OIO75_16595	COG1196	nuclear chromosome segregation
OIO75_16595	COG0739	heme binding
OIO75_16605	COG1702	phosphate starvation-inducible protein PhoH
OIO75_16640	COG1295	ribonuclease BN
OIO75_16645	COG0697	spore germination
OIO75_16650	COG2169	Transcriptional regulator
OIO75_16655	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO75_16695	COG0557	exoribonuclease II activity
OIO75_16700	COG0339	signal peptide processing
OIO75_16705	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OIO75_16735	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OIO75_16740	COG1960	acyl-CoA dehydrogenase activity
OIO75_16905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO75_16905	COG1017	nitric oxide dioxygenase activity
OIO75_16910	COG1959	2 iron, 2 sulfur cluster binding
OIO75_16925	COG1301	dicarboxylic acid transport
OIO75_16930	COG1946	Acyl-CoA thioesterase
OIO75_16950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIO75_16955	COG1040	competence protein
OIO75_16960	COG0494	nUDIX hydrolase
OIO75_16970	COG0598	Magnesium transport protein CorA
OIO75_16980	COG2854	intermembrane phospholipid transfer
OIO75_16990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIO75_16995	COG1127	ABC transporter
OIO75_17005	COG0513	Belongs to the DEAD box helicase family
OIO75_17025	COG0408	coproporphyrinogen oxidase activity
OIO75_17040	COG1960	acyl-CoA dehydrogenase activity
OIO75_17050	COG1983	PspC domain protein
OIO75_17055	COG0517	IMP dehydrogenase activity
OIO75_17080	COG0752	glycyl-tRNA synthetase alpha subunit
OIO75_17105	COG0583	DNA-binding transcription factor activity
OIO75_17145	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_17155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO75_17160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO75_17165	COG0833	amino acid
OIO75_17195	COG1192	Involved in chromosome partitioning
OIO75_17200	COG0628	permease
OIO75_17210	COG1289	transmembrane transporter activity
OIO75_17225	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO75_17230	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OIO75_17240	COG0277	FAD linked oxidase domain protein
OIO75_17245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIO75_17270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIO75_17275	COG5380	lipid catabolic process
OIO75_17295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIO75_17350	COG0194	GDP metabolic process
OIO75_17365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO75_17385	COG3307	-O-antigen
OIO75_17400	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OIO75_17405	COG1704	LemA family
OIO75_17415	COG0493	'glutamate synthase
OIO75_17420	COG0070	glutamate synthase
OIO75_17420	COG0069	glutamate synthase activity
OIO75_17420	COG0067	glutamate synthase
OIO75_17470	COG2226	methyltransferase
OIO75_17485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIO75_17490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIO75_17535	COG0833	amino acid
OIO75_17600	COG0488	(ABC) transporter
OIO75_17605	COG2873	o-acetylhomoserine
OIO75_17610	COG4221	oxidoreductase activity
OIO75_17615	COG0659	secondary active sulfate transmembrane transporter activity
OIO75_17640	COG0427	acetyl-CoA hydrolase
OIO75_17670	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIO75_17690	COG1132	(ABC) transporter
OIO75_17705	COG2329	Antibiotic biosynthesis monooxygenase
OIO75_17720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OIO75_17785	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO75_17790	COG1733	regulation of RNA biosynthetic process
OIO75_17825	COG0667	Aldo Keto reductase
OIO75_17845	COG1309	transcriptional regulator
OIO75_17860	COG0583	DNA-binding transcription factor activity
OIO75_17865	COG2814	Major facilitator Superfamily
OIO75_17900	COG1335	isochorismatase
OIO75_17910	COG1012	belongs to the aldehyde dehydrogenase family
OIO75_17915	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO75_17925	COG1113	amino acid transport
OIO75_17935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO75_17980	COG2814	Major facilitator Superfamily
OIO75_17990	COG0352	thiamine-phosphate diphosphorylase activity
OIO75_17990	COG0351	phosphomethylpyrimidine kinase
OIO75_17990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO75_18010	COG1309	transcriptional regulator
OIO75_18015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIO75_18035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO75_18045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO75_18050	COG3162	membrane
OIO75_18055	COG0784	Response regulator, receiver
OIO75_18055	COG2205	protein histidine kinase activity
OIO75_18055	COG2198	Histidine kinase
OIO75_18080	COG1522	sequence-specific DNA binding
OIO75_18085	COG1335	isochorismatase
OIO75_18090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO75_18100	COG0668	transmembrane transport
OIO75_18105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO75_18110	COG1519	Transferase
OIO75_18115	COG1902	pentaerythritol trinitrate reductase activity
OIO75_18140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OIO75_18165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO75_18165	COG0426	domain, Protein
OIO75_18170	COG4774	siderophore transport
OIO75_18175	COG2119	membrane
OIO75_18185	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO75_18195	COG4942	peptidase
OIO75_18210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIO75_18220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIO75_18240	COG0189	ligase activity
OIO75_18260	COG0708	Exodeoxyribonuclease III
OIO75_18265	COG1393	Belongs to the ArsC family
OIO75_18280	COG3706	GGDEF domain
OIO75_18315	COG2351	hydroxyisourate hydrolase activity
OIO75_18320	COG2233	PERMEase
OIO75_18330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO75_18340	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OIO75_18350	COG3150	esterase
OIO75_18375	COG2918	glutathione biosynthetic process
OIO75_18390	COG2733	membrane
OIO75_18395	COG0436	Aminotransferase
OIO75_18400	COG0534	Mate efflux family protein
OIO75_18485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OIO75_18490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OIO75_18500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIO75_18525	COG1280	lysine exporter protein (LysE YggA)
OIO75_18545	COG0010	Belongs to the arginase family
OIO75_18575	COG2188	Transcriptional regulator
OIO75_18585	COG0523	cobalamin synthesis protein
OIO75_18595	COG1113	amino acid transport
OIO75_18605	COG0625	glutathione transferase activity
OIO75_18625	COG1683	Conserved Protein
OIO75_18630	COG0534	Mate efflux family protein
OIO75_18635	COG0385	Bile acid
OIO75_18640	COG1335	isochorismatase
OIO75_18645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO75_18665	COG2116	formate transmembrane transporter activity
OIO75_18670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OIO75_18685	COG3188	usher protein
OIO75_18690	COG3121	Chaperone
OIO75_18700	COG2983	Belongs to the UPF0260 family
OIO75_18720	COG1194	a g-specific adenine glycosylase
OIO75_18735	COG2818	Glycosylase
OIO75_18740	COG1064	alcohol dehydrogenase
OIO75_18745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO75_18760	COG0583	DNA-binding transcription factor activity
OIO75_18765	COG0656	L-ascorbic acid biosynthetic process
OIO75_18770	COG2814	Major facilitator Superfamily
OIO75_18805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO75_18820	COG2233	PERMEase
OIO75_18860	COG0733	neurotransmitter:sodium symporter activity
OIO75_18900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIO75_18905	COG0657	acetylesterase activity
OIO75_18925	COG0583	DNA-binding transcription factor activity
OIO75_18955	COG2951	lytic endotransglycosylase activity
OIO75_18960	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIO75_18975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIO75_18985	COG0671	phosphoesterase, PA-phosphatase related
OIO75_18990	COG0861	Integral membrane protein TerC family
OIO75_19000	COG0754	glutathionylspermidine amidase activity
OIO75_19010	COG0402	S-adenosylhomocysteine deaminase activity
OIO75_19025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO75_19030	COG1230	cation diffusion facilitator family transporter
OIO75_19045	COG0706	membrane insertase activity
OIO75_19065	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO75_19180	COG4683	PFAM Phage derived protein Gp49-like (DUF891)