locus-tag	class	description
OIO72_00010	COG0592	DNA-directed DNA polymerase activity
OIO72_00020	COG0187	DNA topoisomerase II activity
OIO72_00030	COG0586	Pfam SNARE associated Golgi protein
OIO72_00035	COG0488	(ABC) transporter
OIO72_00060	COG0596	Alpha beta hydrolase
OIO72_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OIO72_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO72_00110	COG1047	Peptidyl-prolyl cis-trans
OIO72_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIO72_00125	COG0196	riboflavin kinase activity
OIO72_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO72_00140	COG1309	transcriptional regulator
OIO72_00145	COG1116	anion transmembrane transporter activity
OIO72_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO72_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO72_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO72_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO72_00185	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_00190	COG0546	phosphoglycolate phosphatase activity
OIO72_00215	COG1017	nitric oxide dioxygenase activity
OIO72_00215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO72_00250	COG3023	N-Acetylmuramoyl-L-alanine amidase
OIO72_00255	COG0728	peptidoglycan biosynthetic process
OIO72_00285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OIO72_00305	COG0438	transferase activity, transferring glycosyl groups
OIO72_00315	COG0438	transferase activity, transferring glycosyl groups
OIO72_00320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OIO72_00330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OIO72_00340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIO72_00355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO72_00360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO72_00370	COG2186	Transcriptional regulator
OIO72_00380	COG0277	FAD linked oxidase domain protein
OIO72_00385	COG1448	Aminotransferase
OIO72_00395	COG1802	Transcriptional regulator
OIO72_00410	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIO72_00435	COG1051	belongs to the nudix hydrolase family
OIO72_00465	COG0564	pseudouridine synthase activity
OIO72_00505	COG0251	oxidation-reduction process
OIO72_00510	COG1113	amino acid transport
OIO72_00515	COG1113	amino acid transport
OIO72_00535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO72_00540	COG1960	acyl-CoA dehydrogenase activity
OIO72_00545	COG1024	Enoyl-CoA hydratase
OIO72_00550	COG1024	Enoyl-CoA hydratase
OIO72_00555	COG0477	Major facilitator Superfamily
OIO72_00560	COG3916	Acyl-homoserine-lactone synthase
OIO72_00570	COG2197	response regulator
OIO72_00580	COG1960	acyl-CoA dehydrogenase activity
OIO72_00585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIO72_00585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OIO72_00585	COG3321	synthase
OIO72_00585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO72_00605	COG2267	carboxylic ester hydrolase activity
OIO72_00625	COG0271	Belongs to the BolA IbaG family
OIO72_00635	COG1192	Involved in chromosome partitioning
OIO72_00650	COG0586	Pfam SNARE associated Golgi protein
OIO72_00655	COG2259	Doxx family
OIO72_00660	COG4399	Belongs to the UPF0754 family
OIO72_00665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO72_00665	COG0519	Catalyzes the synthesis of GMP from XMP
OIO72_00710	COG0281	malic enzyme
OIO72_00720	COG2837	iron assimilation
OIO72_00725	COG1280	lysine exporter protein (LysE YggA)
OIO72_00730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIO72_00735	COG1121	(ABC) transporter
OIO72_00800	COG0386	Belongs to the glutathione peroxidase family
OIO72_00815	COG1309	transcriptional regulator
OIO72_00820	COG0697	spore germination
OIO72_00830	COG0758	DNA mediated transformation
OIO72_00900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIO72_00910	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIO72_00950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO72_00955	COG3757	hydrolase, family 25
OIO72_00960	COG0477	Major facilitator Superfamily
OIO72_00970	COG1253	flavin adenine dinucleotide binding
OIO72_00980	COG2860	membrane
OIO72_00985	COG0477	Major facilitator Superfamily
OIO72_00995	COG0318	PFAM AMP-dependent synthetase and ligase
OIO72_01010	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIO72_01035	COG1061	Type III restriction enzyme res subunit
OIO72_01040	COG1002	Type II restriction enzyme, methylase subunits
OIO72_01065	COG0347	Belongs to the P(II) protein family
OIO72_01070	COG0004	ammonium transporteR
OIO72_01080	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO72_01080	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO72_01120	COG0795	lipopolysaccharide-transporting ATPase activity
OIO72_01125	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIO72_01130	COG0793	Belongs to the peptidase S41A family
OIO72_01145	COG2197	response regulator
OIO72_01155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIO72_01165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO72_01170	COG4974	Belongs to the 'phage' integrase family
OIO72_01195	COG0772	Belongs to the SEDS family
OIO72_01200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO72_01205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OIO72_01210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO72_01255	COG0589	response to stress
OIO72_01260	COG0659	secondary active sulfate transmembrane transporter activity
OIO72_01270	COG1002	Type II restriction enzyme, methylase subunits
OIO72_01275	COG1061	Type III restriction enzyme res subunit
OIO72_01320	COG0697	spore germination
OIO72_01325	COG1538	Outer membrane efflux protein
OIO72_01345	COG3275	phosphorelay sensor kinase activity
OIO72_01355	COG0181	hydroxymethylbilane synthase activity
OIO72_01400	COG1716	ATPase activity
OIO72_01405	COG0546	phosphoglycolate phosphatase activity
OIO72_01505	COG2056	Na+-H+ antiporter family
OIO72_01520	COG0326	Molecular chaperone. Has ATPase activity
OIO72_01535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIO72_01595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIO72_01600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO72_01600	COG2169	Transcriptional regulator
OIO72_01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIO72_01640	COG0497	DNA recombination
OIO72_01655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO72_01665	COG0237	dephospho-CoA kinase activity
OIO72_01715	COG0195	Participates in both transcription termination and antitermination
OIO72_01730	COG1320	monovalent cation:proton antiporter activity
OIO72_01735	COG2212	antiporter activity
OIO72_01740	COG1863	multisubunit Na H antiporter MnhE subunit
OIO72_01745	COG0651	ATP synthesis coupled electron transport
OIO72_01750	COG1006	Multisubunit Na H antiporter MnhC subunit
OIO72_01755	COG2111	Na H antiporter
OIO72_01755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO72_01770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIO72_01790	COG2226	methyltransferase
OIO72_01810	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OIO72_01815	COG1074	ATP-dependent DNA helicase activity
OIO72_01820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO72_01825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO72_01840	COG0598	Magnesium transport protein CorA
OIO72_01845	COG0789	Transcriptional regulator
OIO72_01850	COG0484	heat shock protein binding
OIO72_01865	COG0475	glutathione-regulated potassium exporter activity
OIO72_01865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO72_01870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIO72_01890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO72_01900	COG4535	Mg2 and Co2 transporter CorC
OIO72_01905	COG0425	Belongs to the sulfur carrier protein TusA family
OIO72_01915	COG0644	oxidoreductase
OIO72_01915	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OIO72_01925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO72_01940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO72_01945	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OIO72_01955	COG0493	'glutamate synthase
OIO72_01955	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO72_01980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OIO72_01995	COG0534	Mate efflux family protein
OIO72_02005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIO72_02010	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_02015	COG0583	DNA-binding transcription factor activity
OIO72_02030	COG0318	PFAM AMP-dependent synthetase and ligase
OIO72_02035	COG1530	ribonuclease E activity
OIO72_02045	COG0546	phosphoglycolate phosphatase activity
OIO72_02050	COG2378	regulation of single-species biofilm formation
OIO72_02055	COG0625	glutathione transferase activity
OIO72_02065	COG0583	DNA-binding transcription factor activity
OIO72_02120	COG0473	3-isopropylmalate dehydrogenase activity
OIO72_02175	COG1301	dicarboxylic acid transport
OIO72_02185	COG1560	Kdo2-lipid A biosynthetic process
OIO72_02190	COG1280	lysine exporter protein (LysE YggA)
OIO72_02195	COG0488	(ABC) transporter
OIO72_02200	COG2900	Belongs to the SlyX family
OIO72_02210	COG1733	regulation of RNA biosynthetic process
OIO72_02235	COG0210	DNA helicase
OIO72_02240	COG0724	RNA recognition motif
OIO72_02260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO72_02260	COG4651	solute:proton antiporter activity
OIO72_02285	COG0788	formyltetrahydrofolate deformylase activity
OIO72_02385	COG2813	Specifically methylates the guanine in position
OIO72_02385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO72_02395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO72_02405	COG4774	siderophore transport
OIO72_02415	COG0740	serine-type endopeptidase activity
OIO72_02435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO72_02435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO72_02440	COG0280	phosphate acetyltransferase
OIO72_02440	COG0857	belongs to the CobB CobQ family
OIO72_02445	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIO72_02455	COG0800	Aldolase
OIO72_02465	COG3265	gluconokinase activity
OIO72_02470	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_02480	COG2267	carboxylic ester hydrolase activity
OIO72_02495	COG0793	Belongs to the peptidase S41A family
OIO72_02530	COG1426	Protein conserved in bacteria
OIO72_02570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OIO72_02580	COG1162	GTPase activity
OIO72_02585	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIO72_02600	COG1538	Outer membrane efflux protein
OIO72_02605	COG0577	efflux transmembrane transporter activity
OIO72_02605	COG1136	(ABC) transporter
OIO72_02610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO72_02635	COG0028	Belongs to the TPP enzyme family
OIO72_02640	COG0440	acetolactate synthase activity
OIO72_02670	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIO72_02685	COG0084	hydrolase, TatD family'
OIO72_02695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OIO72_02705	COG0583	DNA-binding transcription factor activity
OIO72_02715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO72_02785	COG1294	oxidase, subunit
OIO72_02790	COG1271	oxidase subunit
OIO72_02805	COG4774	siderophore transport
OIO72_02875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO72_02885	COG2814	Major facilitator Superfamily
OIO72_02895	COG0697	spore germination
OIO72_02930	COG3622	Belongs to the hyi family
OIO72_02935	COG2084	Dehydrogenase
OIO72_02940	COG1024	Enoyl-CoA hydratase
OIO72_02945	COG5002	protein histidine kinase activity
OIO72_02945	COG0784	Response regulator, receiver
OIO72_02945	COG2205	protein histidine kinase activity
OIO72_02965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO72_02975	COG3956	TIGRFAM MazG family protein
OIO72_02980	COG1555	photosystem II stabilization
OIO72_02985	COG0617	tRNA 3'-terminal CCA addition
OIO72_02990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OIO72_03010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO72_03015	COG3028	Belongs to the UPF0307 family
OIO72_03020	COG0318	PFAM AMP-dependent synthetase and ligase
OIO72_03035	COG0625	glutathione transferase activity
OIO72_03040	COG1238	metal cluster binding
OIO72_03085	COG0072	phenylalanine-tRNA ligase activity
OIO72_03115	COG0248	Ppx GppA phosphatase
OIO72_03125	COG0037	tRNA processing
OIO72_03165	COG1764	response to oxidative stress
OIO72_03170	COG1846	Transcriptional regulator
OIO72_03180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO72_03240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIO72_03245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIO72_03250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIO72_03320	COG1214	PFAM Peptidase M22, glycoprotease
OIO72_03335	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO72_03345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIO72_03350	COG0561	phosphatase activity
OIO72_03360	COG2132	Multicopper oxidase
OIO72_03380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO72_03385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIO72_03390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIO72_03420	COG1063	alcohol dehydrogenase
OIO72_03425	COG0583	DNA-binding transcription factor activity
OIO72_03430	COG1960	acyl-CoA dehydrogenase activity
OIO72_03435	COG2814	Major facilitator Superfamily
OIO72_03440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO72_03450	COG1053	succinate dehydrogenase
OIO72_03455	COG0583	DNA-binding transcription factor activity
OIO72_03470	COG0583	DNA-binding transcription factor activity
OIO72_03480	COG0583	DNA-binding transcription factor activity
OIO72_03495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO72_03540	COG0384	phenazine biosynthesis protein PhzF
OIO72_03560	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_03570	COG0477	Major facilitator Superfamily
OIO72_03605	COG0697	spore germination
OIO72_03610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO72_03630	COG0745	RESPONSE REGULATOR receiver
OIO72_03670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIO72_03700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO72_03705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIO72_03730	COG0583	DNA-binding transcription factor activity
OIO72_03750	COG0668	transmembrane transport
OIO72_03760	COG2081	HI0933 family
OIO72_03765	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO72_03795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO72_03795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO72_03805	COG0489	protein tyrosine kinase activity
OIO72_03855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO72_03865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIO72_03880	COG0730	response to heat
OIO72_03890	COG1196	nuclear chromosome segregation
OIO72_03910	COG2223	nitrite transmembrane transporter activity
OIO72_03915	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OIO72_03920	COG1877	trehalose-phosphatase activity
OIO72_03925	COG0596	Alpha beta hydrolase
OIO72_03925	COG2226	methyltransferase
OIO72_03925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO72_03940	COG4106	trans-aconitate 2-methyltransferase activity
OIO72_03955	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIO72_03960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIO72_03965	COG0009	L-threonylcarbamoyladenylate synthase
OIO72_03970	COG3101	peptidyl-lysine hydroxylation
OIO72_03975	COG1399	metal-binding, possibly nucleic acid-binding protein
OIO72_04000	COG1652	LysM domain
OIO72_04005	COG0351	phosphomethylpyrimidine kinase
OIO72_04005	COG0352	thiamine-phosphate diphosphorylase activity
OIO72_04005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO72_04015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIO72_04045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO72_04075	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OIO72_04090	COG0358	DNA primase activity
OIO72_04100	COG0564	pseudouridine synthase activity
OIO72_04125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO72_04155	COG0583	DNA-binding transcription factor activity
OIO72_04160	COG0473	3-isopropylmalate dehydrogenase activity
OIO72_04170	COG0657	acetylesterase activity
OIO72_04180	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_04200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIO72_04200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO72_04215	COG1981	membrane
OIO72_04260	COG0456	acetyltransferase
OIO72_04270	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OIO72_04275	COG0492	ferredoxin-NADP+ reductase activity
OIO72_04280	COG1674	ftsk spoiiie
OIO72_04280	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OIO72_04285	COG1280	lysine exporter protein (LysE YggA)
OIO72_04300	COG2894	cell division
OIO72_04315	COG0204	Acyl-transferase
OIO72_04320	COG2885	chlorophyll binding
OIO72_04325	COG0210	DNA helicase
OIO72_04335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO72_04350	COG0121	glutamine amidotransferase
OIO72_04370	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO72_04375	COG0735	belongs to the Fur family
OIO72_04400	COG0420	3'-5' exonuclease activity
OIO72_04420	COG1090	epimerase
OIO72_04435	COG2050	protein possibly involved in aromatic compounds catabolism
OIO72_04445	COG2814	Major facilitator Superfamily
OIO72_04450	COG0405	Gamma-glutamyltransferase
OIO72_04530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO72_04615	COG1484	DNA-dependent DNA replication
OIO72_04835	COG2026	Addiction module toxin, RelE StbE family
OIO72_04875	COG0592	DNA-directed DNA polymerase activity
OIO72_04960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO72_05020	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OIO72_05030	COG0477	Major facilitator Superfamily
OIO72_05035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO72_05045	COG1595	DNA-templated transcription, initiation
OIO72_05100	COG0531	amino acid
OIO72_05105	COG2040	homocysteine
OIO72_05130	COG1309	transcriptional regulator
OIO72_05135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO72_05140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO72_05150	COG1607	acyl-coa hydrolase
OIO72_05160	COG0523	cobalamin synthesis protein
OIO72_05170	COG4681	YaeQ
OIO72_05180	COG1649	PFAM Uncharacterised BCR, COG1649
OIO72_05180	COG0726	polysaccharide deacetylase
OIO72_05185	COG1215	transferase activity, transferring glycosyl groups
OIO72_05195	COG1024	Enoyl-CoA hydratase
OIO72_05210	COG1414	Transcriptional regulator
OIO72_05230	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_05240	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO72_05245	COG2271	Major facilitator Superfamily
OIO72_05255	COG2267	carboxylic ester hydrolase activity
OIO72_05260	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_05275	COG0028	Belongs to the TPP enzyme family
OIO72_05285	COG0477	Major facilitator Superfamily
OIO72_05290	COG0242	peptide deformylase activity
OIO72_05295	COG2066	Belongs to the glutaminase family
OIO72_05300	COG2207	Transcriptional regulator
OIO72_05320	COG0583	DNA-binding transcription factor activity
OIO72_05325	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_05330	COG2271	Major facilitator Superfamily
OIO72_05335	COG3959	Transketolase, thiamine diphosphate binding domain
OIO72_05340	COG3958	Transketolase
OIO72_05350	COG0306	phosphate transporter
OIO72_05375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIO72_05420	COG4181	ATPase activity
OIO72_05425	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OIO72_05455	COG0583	DNA-binding transcription factor activity
OIO72_05465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO72_05470	COG1773	rubredoxin
OIO72_05520	COG2851	Citrate transporter
OIO72_05525	COG1253	flavin adenine dinucleotide binding
OIO72_05565	COG0804	urea catabolic process
OIO72_05575	COG0830	nickel cation binding
OIO72_05590	COG0742	ribosomal rna small subunit methyltransferase
OIO72_05595	COG0768	penicillin binding
OIO72_05620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIO72_05625	COG2878	Part of a membrane complex involved in electron transport
OIO72_05630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO72_05640	COG3384	dioxygenase
OIO72_05660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIO72_05840	COG5410	chromosome segregation
OIO72_06005	COG2194	sulfuric ester hydrolase activity
OIO72_06040	COG0006	proline dipeptidase activity
OIO72_06045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO72_06050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO72_06070	COG1279	arginine transmembrane transporter activity
OIO72_06075	COG0583	DNA-binding transcription factor activity
OIO72_06115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO72_06120	COG1388	LysM domain
OIO72_06120	COG1388	LysM domain
OIO72_06120	COG0741	lytic transglycosylase activity
OIO72_06120	COG0741	lytic transglycosylase activity
OIO72_06130	COG4174	ABC transporter (Permease)
OIO72_06135	COG4239	(ABC) transporter, permease
OIO72_06140	COG4172	Belongs to the ABC transporter superfamily
OIO72_06165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO72_06175	COG3706	GGDEF domain
OIO72_06175	COG4251	negative regulation of phosphorylation
OIO72_06175	COG2203	Gaf domain
OIO72_06175	COG5001	Diguanylate cyclase
OIO72_06185	COG1902	pentaerythritol trinitrate reductase activity
OIO72_06185	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO72_06200	COG4269	membrane
OIO72_06220	COG3209	COG3209 Rhs family protein
OIO72_06260	COG1113	amino acid transport
OIO72_06270	COG0531	amino acid
OIO72_06290	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_06310	COG1113	amino acid transport
OIO72_06355	COG0697	spore germination
OIO72_06360	COG2721	sulfolactate sulfo-lyase activity
OIO72_06365	COG2271	Major facilitator Superfamily
OIO72_06370	COG4948	Mandelate Racemase Muconate Lactonizing
OIO72_06380	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_06385	COG2186	Transcriptional regulator
OIO72_06410	COG1960	acyl-CoA dehydrogenase activity
OIO72_06420	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_06425	COG1024	Enoyl-CoA hydratase
OIO72_06430	COG2814	Major facilitator Superfamily
OIO72_06450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO72_06495	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIO72_06500	COG2072	flavoprotein involved in K transport
OIO72_06505	COG0300	oxidoreductase activity
OIO72_06515	COG1309	transcriptional regulator
OIO72_06520	COG1741	Belongs to the pirin family
OIO72_06535	COG2072	flavoprotein involved in K transport
OIO72_06545	COG2252	PERMEase
OIO72_06550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIO72_06555	COG3038	cytochrome b561
OIO72_06565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIO72_06575	COG0527	aspartate kinase activity
OIO72_06585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIO72_06600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIO72_06615	COG0667	Aldo Keto reductase
OIO72_06630	COG1765	OsmC-like protein
OIO72_06645	COG0542	response to heat
OIO72_06680	COG2885	chlorophyll binding
OIO72_06690	COG0625	glutathione transferase activity
OIO72_06850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIO72_06870	COG3634	alkyl hydroperoxide reductase activity
OIO72_06880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIO72_06890	COG0450	alkyl hydroperoxide reductase
OIO72_06895	COG1643	Atp-dependent helicase
OIO72_06910	COG2814	Major facilitator Superfamily
OIO72_06915	COG3135	benzoate transporter
OIO72_06920	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_06925	COG0543	2 iron, 2 sulfur cluster binding
OIO72_06925	COG0633	Ferredoxin
OIO72_06935	COG4638	Rieske (2fe-2S)
OIO72_06945	COG0583	DNA-binding transcription factor activity
OIO72_06995	COG1570	exodeoxyribonuclease VII activity
OIO72_07025	COG1280	lysine exporter protein (LysE YggA)
OIO72_07030	COG1278	Cold shock
OIO72_07065	COG2814	Major facilitator Superfamily
OIO72_07105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OIO72_07105	COG0517	IMP dehydrogenase activity
OIO72_07110	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OIO72_07120	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OIO72_07125	COG1137	ATPase activity
OIO72_07160	COG4122	O-methyltransferase activity
OIO72_07170	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OIO72_07185	COG1522	sequence-specific DNA binding
OIO72_07190	COG5006	permease, DMT superfamily
OIO72_07200	COG1560	Kdo2-lipid A biosynthetic process
OIO72_07210	COG0598	Magnesium transport protein CorA
OIO72_07240	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO72_07245	COG1116	anion transmembrane transporter activity
OIO72_07250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO72_07275	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO72_07335	COG1914	H( )-stimulated, divalent metal cation uptake system
OIO72_07355	COG4770	biotin carboxylase activity
OIO72_07360	COG0038	chloride channel
OIO72_07400	COG1309	transcriptional regulator
OIO72_07410	COG1063	alcohol dehydrogenase
OIO72_07425	COG0439	Biotin carboxylase
OIO72_07430	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO72_07435	COG1733	regulation of RNA biosynthetic process
OIO72_07445	COG0864	Transcriptional regulator
OIO72_07455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO72_07460	COG1116	anion transmembrane transporter activity
OIO72_07590	COG0590	tRNA wobble adenosine to inosine editing
OIO72_07595	COG2807	transmembrane transport
OIO72_07610	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OIO72_07620	COG0789	Transcriptional regulator
OIO72_07630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO72_07650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO72_07675	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_07680	COG0531	amino acid
OIO72_07685	COG1760	l-serine dehydratase
OIO72_07690	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_07690	COG2030	dehydratase
OIO72_07695	COG3396	Phenylacetate-CoA oxygenase
OIO72_07700	COG3460	Phenylacetate-CoA oxygenase
OIO72_07705	COG3396	Phenylacetate-CoA oxygenase
OIO72_07710	COG2151	metal-sulfur cluster biosynthetic enzyme
OIO72_07715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO72_07720	COG1024	Enoyl-CoA hydratase
OIO72_07725	COG1024	Enoyl-CoA hydratase
OIO72_07730	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO72_07735	COG0183	Belongs to the thiolase family
OIO72_07740	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OIO72_07745	COG3327	negative regulation of DNA-templated transcription, initiation
OIO72_07755	COG2050	protein possibly involved in aromatic compounds catabolism
OIO72_07765	COG0556	nucleotide-excision repair
OIO72_07800	COG1278	Cold shock
OIO72_07810	COG2207	Transcriptional regulator
OIO72_07910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO72_07915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO72_07920	COG2271	Major facilitator Superfamily
OIO72_07925	COG0753	catalase activity
OIO72_07930	COG3038	cytochrome b561
OIO72_07950	COG2267	carboxylic ester hydrolase activity
OIO72_07955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO72_07960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO72_07965	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_07975	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO72_07985	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_07990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO72_07995	COG0583	DNA-binding transcription factor activity
OIO72_08005	COG1414	Transcriptional regulator
OIO72_08010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO72_08025	COG1840	ABC-type Fe3 transport system, periplasmic component
OIO72_08030	COG3842	ATPase activity
OIO72_08050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO72_08070	COG0583	DNA-binding transcription factor activity
OIO72_08080	COG4770	biotin carboxylase activity
OIO72_08085	COG1024	Enoyl-CoA hydratase
OIO72_08090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO72_08095	COG1960	acyl-CoA dehydrogenase activity
OIO72_08100	COG1309	transcriptional regulator
OIO72_08105	COG0318	PFAM AMP-dependent synthetase and ligase
OIO72_08125	COG0583	DNA-binding transcription factor activity
OIO72_08175	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_08195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIO72_08215	COG2205	protein histidine kinase activity
OIO72_08215	COG0784	Response regulator, receiver
OIO72_08235	COG0765	amino acid transport
OIO72_08240	COG0765	amino acid transport
OIO72_08245	COG1126	abc transporter atp-binding protein
OIO72_08250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO72_08255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO72_08270	COG1280	lysine exporter protein (LysE YggA)
OIO72_08280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIO72_08285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO72_08290	COG1045	serine acetyltransferase
OIO72_08300	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_08305	COG0583	DNA-binding transcription factor activity
OIO72_08310	COG0625	glutathione transferase activity
OIO72_08315	COG0625	glutathione transferase activity
OIO72_08320	COG0583	DNA-binding transcription factor activity
OIO72_08330	COG1346	cytolysis
OIO72_08350	COG2814	Major facilitator Superfamily
OIO72_08360	COG0583	DNA-binding transcription factor activity
OIO72_08370	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OIO72_08375	COG3052	prosthetic group binding
OIO72_08395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OIO72_08415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO72_08425	COG1294	oxidase, subunit
OIO72_08430	COG1271	oxidase subunit
OIO72_08450	COG0477	Major facilitator Superfamily
OIO72_08460	COG4521	taurine ABC transporter
OIO72_08480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO72_08485	COG2175	clavaminate synthase activity
OIO72_08495	COG1953	Uracil, thiamine, allantoin
OIO72_08505	COG0583	DNA-binding transcription factor activity
OIO72_08515	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIO72_08530	COG0640	Transcriptional regulator
OIO72_08535	COG0798	PFAM Bile acid sodium symporter
OIO72_08540	COG0583	DNA-binding transcription factor activity
OIO72_08555	COG3634	alkyl hydroperoxide reductase activity
OIO72_08590	COG1301	dicarboxylic acid transport
OIO72_08595	COG0436	Aminotransferase
OIO72_08605	COG0386	Belongs to the glutathione peroxidase family
OIO72_08645	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO72_08670	COG0012	GTP binding
OIO72_08675	COG2011	ABC-type metal ion transport system permease component
OIO72_08680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO72_08690	COG1464	Belongs to the NlpA lipoprotein family
OIO72_08720	COG0765	amino acid transport
OIO72_08725	COG0765	amino acid transport
OIO72_08730	COG1126	abc transporter atp-binding protein
OIO72_08740	COG1522	sequence-specific DNA binding
OIO72_08755	COG1309	transcriptional regulator
OIO72_08775	COG0583	DNA-binding transcription factor activity
OIO72_08785	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO72_08795	COG0697	spore germination
OIO72_08820	COG3121	Chaperone
OIO72_08825	COG3539	Fimbrial protein
OIO72_08850	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIO72_08850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIO72_08895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIO72_08905	COG2353	YceI-like domain
OIO72_08915	COG3698	Phosphodiester glycosidase
OIO72_08930	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIO72_08935	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO72_08935	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO72_08935	COG0506	proline dehydrogenase activity
OIO72_08945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO72_08950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIO72_08970	COG1132	(ABC) transporter
OIO72_08975	COG3122	Protein conserved in bacteria
OIO72_08980	COG3619	membrane
OIO72_08990	COG0640	Transcriptional regulator
OIO72_09000	COG2850	peptidyl-arginine hydroxylation
OIO72_09005	COG0424	maF-like protein
OIO72_09025	COG0191	fructose-bisphosphate aldolase activity
OIO72_09030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO72_09045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIO72_09055	COG1192	Involved in chromosome partitioning
OIO72_09060	COG1475	DNA binding
OIO72_09065	COG0811	peptide transport
OIO72_09075	COG1132	(ABC) transporter
OIO72_09080	COG1663	tetraacyldisaccharide 4'-kinase activity
OIO72_09100	COG0084	hydrolase, TatD family'
OIO72_09165	COG0776	regulation of translation
OIO72_09195	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OIO72_09200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIO72_09235	COG4166	transmembrane transport
OIO72_09245	COG0339	signal peptide processing
OIO72_09255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIO72_09290	COG0702	epimerase
OIO72_09295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO72_09315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO72_09345	COG0316	Belongs to the HesB IscA family
OIO72_09350	COG0822	iron-sulfur transferase activity
OIO72_09375	COG0776	regulation of translation
OIO72_09380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO72_09385	COG2207	Transcriptional regulator
OIO72_09390	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO72_09395	COG1960	acyl-CoA dehydrogenase activity
OIO72_09400	COG1960	acyl-CoA dehydrogenase activity
OIO72_09415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIO72_09430	COG2814	Major facilitator Superfamily
OIO72_09435	COG4264	IucA IucC family
OIO72_09440	COG4264	IucA IucC family
OIO72_09450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO72_09480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO72_09495	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIO72_09500	COG0406	alpha-ribazole phosphatase activity
OIO72_09515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO72_09520	COG0730	response to heat
OIO72_09545	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO72_09560	COG1131	(ABC) transporter
OIO72_09565	COG0842	Transport permease protein
OIO72_09570	COG0842	Transport permease protein
OIO72_09625	COG2226	methyltransferase
OIO72_09650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIO72_09685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO72_09695	COG0133	tryptophan synthase activity
OIO72_09710	COG3706	GGDEF domain
OIO72_09725	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO72_09730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OIO72_09735	COG0022	dehydrogenase e1 component
OIO72_09740	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO72_09745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO72_09755	COG1063	alcohol dehydrogenase
OIO72_09760	COG3781	membrane
OIO72_09770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO72_09770	COG3453	Protein conserved in bacteria
OIO72_09785	COG0730	response to heat
OIO72_09800	COG2207	Transcriptional regulator
OIO72_09800	COG3708	Transcriptional regulator
OIO72_09805	COG1733	regulation of RNA biosynthetic process
OIO72_09810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIO72_09820	COG2188	Transcriptional regulator
OIO72_09835	COG4521	taurine ABC transporter
OIO72_09840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO72_09860	COG0477	Major facilitator Superfamily
OIO72_09870	COG1027	Aspartate ammonia-lyase
OIO72_09890	COG0583	DNA-binding transcription factor activity
OIO72_09895	COG0583	DNA-binding transcription factor activity
OIO72_09900	COG0183	Belongs to the thiolase family
OIO72_09905	COG2031	fatty acid transporter
OIO72_09920	COG0583	DNA-binding transcription factor activity
OIO72_09930	COG2610	gluconate transmembrane transporter activity
OIO72_09935	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_09940	COG2207	Transcriptional regulator
OIO72_09955	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_09965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO72_09980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO72_09980	COG0543	2 iron, 2 sulfur cluster binding
OIO72_09985	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO72_09990	COG4638	Rieske (2fe-2S)
OIO72_10000	COG0725	ABC transporter, periplasmic molybdate-binding protein
OIO72_10005	COG4149	molybdate abc transporter
OIO72_10010	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OIO72_10015	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_10020	COG1535	isochorismatase
OIO72_10020	COG3433	isochorismatase activity
OIO72_10080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO72_10110	COG0753	catalase activity
OIO72_10120	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO72_10145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO72_10150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO72_10155	COG0745	RESPONSE REGULATOR receiver
OIO72_10160	COG2205	protein histidine kinase activity
OIO72_10170	COG2207	Transcriptional regulator
OIO72_10180	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_10210	COG3320	Male sterility
OIO72_10210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO72_10215	COG2814	Major facilitator Superfamily
OIO72_10240	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OIO72_10290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO72_10310	COG1120	ATPase activity
OIO72_10315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO72_10325	COG1064	alcohol dehydrogenase
OIO72_10340	COG2207	Transcriptional regulator
OIO72_10345	COG2084	Dehydrogenase
OIO72_10355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO72_10360	COG0583	DNA-binding transcription factor activity
OIO72_10370	COG0129	dihydroxy-acid dehydratase activity
OIO72_10375	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_10380	COG1846	Transcriptional regulator
OIO72_10385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO72_10390	COG1960	acyl-CoA dehydrogenase activity
OIO72_10395	COG0477	Major facilitator Superfamily
OIO72_10410	COG3971	2-oxopent-4-enoate hydratase activity
OIO72_10420	COG3384	dioxygenase
OIO72_10425	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_10435	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO72_10445	COG2814	Major facilitator Superfamily
OIO72_10450	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO72_10465	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_10485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO72_10505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO72_10540	COG0583	DNA-binding transcription factor activity
OIO72_10555	COG2188	Transcriptional regulator
OIO72_10610	COG1473	amidohydrolase
OIO72_10620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO72_10620	COG0475	glutathione-regulated potassium exporter activity
OIO72_10630	COG0583	DNA-binding transcription factor activity
OIO72_10635	COG1335	isochorismatase
OIO72_10645	COG1309	transcriptional regulator
OIO72_10680	COG1902	pentaerythritol trinitrate reductase activity
OIO72_10680	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO72_10685	COG1846	Transcriptional regulator
OIO72_10710	COG0753	catalase activity
OIO72_10725	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_10740	COG3162	membrane
OIO72_10750	COG3829	transcription factor binding
OIO72_10755	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_10760	COG1960	acyl-CoA dehydrogenase activity
OIO72_10775	COG3231	kanamycin kinase activity
OIO72_10780	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_10800	COG2186	Transcriptional regulator
OIO72_10810	COG0583	DNA-binding transcription factor activity
OIO72_10815	COG4948	Mandelate Racemase Muconate Lactonizing
OIO72_10820	COG4829	muconolactone delta-isomerase
OIO72_10830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO72_10835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO72_10840	COG0183	Belongs to the thiolase family
OIO72_10845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO72_10855	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_10865	COG3733	amine oxidase
OIO72_10875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO72_10885	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_10895	COG4638	Rieske (2fe-2S)
OIO72_10915	COG0154	amidase activity
OIO72_10925	COG2814	Major facilitator Superfamily
OIO72_10950	COG1960	acyl-CoA dehydrogenase activity
OIO72_10955	COG0583	DNA-binding transcription factor activity
OIO72_10960	COG1414	Transcriptional regulator
OIO72_10975	COG2391	methyltransferase activity
OIO72_10985	COG4993	Dehydrogenase
OIO72_10990	COG3659	wide pore channel activity
OIO72_10995	COG3420	alginic acid biosynthetic process
OIO72_11000	COG0710	3-dehydroquinate dehydratase activity
OIO72_11005	COG3485	protocatechuate 3,4-dioxygenase
OIO72_11010	COG3485	protocatechuate 3,4-dioxygenase
OIO72_11015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO72_11020	COG2271	Major facilitator Superfamily
OIO72_11025	COG0596	Alpha beta hydrolase
OIO72_11030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIO72_11035	COG0183	Belongs to the thiolase family
OIO72_11040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO72_11045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO72_11055	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OIO72_11060	COG2323	membrane
OIO72_11105	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO72_11105	COG1902	pentaerythritol trinitrate reductase activity
OIO72_11120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO72_11130	COG0542	response to heat
OIO72_11135	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIO72_11165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO72_11170	COG0569	domain protein
OIO72_11175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIO72_11190	COG4774	siderophore transport
OIO72_11195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIO72_11205	COG1585	Membrane protein implicated in regulation of membrane protease activity
OIO72_11220	COG1294	oxidase, subunit
OIO72_11225	COG4890	Cyd operon protein YbgT
OIO72_11235	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OIO72_11245	COG0552	protein localization to endoplasmic reticulum
OIO72_11270	COG0517	IMP dehydrogenase activity
OIO72_11270	COG0516	GMP reductase activity
OIO72_11275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO72_11280	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OIO72_11290	COG0583	DNA-binding transcription factor activity
OIO72_11295	COG0024	Methionine aminopeptidase
OIO72_11325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO72_11325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIO72_11330	COG1105	Belongs to the carbohydrate kinase PfkB family
OIO72_11335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO72_11335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO72_11335	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIO72_11355	COG3300	MHYT domain
OIO72_11355	COG5001	Diguanylate cyclase
OIO72_11370	COG2135	peptidase activity
OIO72_11375	COG0659	secondary active sulfate transmembrane transporter activity
OIO72_11395	COG1113	amino acid transport
OIO72_11405	COG1522	sequence-specific DNA binding
OIO72_11430	COG1011	Hydrolase
OIO72_11435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OIO72_11445	COG2137	regulation of response to DNA damage stimulus
OIO72_11460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO72_11480	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO72_11495	COG0575	Belongs to the CDS family
OIO72_11500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIO72_11520	COG3852	Histidine kinase
OIO72_11525	COG2204	response regulator
OIO72_11580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO72_11585	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OIO72_11605	COG0697	spore germination
OIO72_11610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO72_11625	COG0315	cyclic pyranopterin monophosphate synthase activity
OIO72_11625	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIO72_11645	COG0243	molybdopterin cofactor binding
OIO72_11655	COG0243	molybdopterin cofactor binding
OIO72_11660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO72_11665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO72_11665	COG2146	nitrite reductase [NAD(P)H] activity
OIO72_11675	COG0745	RESPONSE REGULATOR receiver
OIO72_11680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO72_11680	COG1116	anion transmembrane transporter activity
OIO72_11700	COG0511	ligase activity, forming carbon-carbon bonds
OIO72_11715	COG2814	Major facilitator Superfamily
OIO72_11735	COG0069	glutamate synthase activity
OIO72_11755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIO72_11765	COG1454	alcohol dehydrogenase
OIO72_11770	COG0824	Thioesterase
OIO72_11800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO72_11805	COG2030	dehydratase
OIO72_11815	COG0183	Belongs to the thiolase family
OIO72_11825	COG0583	DNA-binding transcription factor activity
OIO72_11830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIO72_11840	COG1522	sequence-specific DNA binding
OIO72_11845	COG3135	benzoate transporter
OIO72_11855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIO72_11880	COG0589	response to stress
OIO72_11885	COG0488	(ABC) transporter
OIO72_11905	COG4773	Receptor
OIO72_11935	COG0668	transmembrane transport
OIO72_11945	COG1309	transcriptional regulator
OIO72_11965	COG1605	Chorismate mutase
OIO72_11985	COG0308	aminopeptidase N
OIO72_12005	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OIO72_12015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO72_12020	COG1454	alcohol dehydrogenase
OIO72_12040	COG0531	amino acid
OIO72_12045	COG4303	Ethanolamine ammonia lyase large subunit
OIO72_12050	COG4302	ethanolamine ammonia-lyase activity
OIO72_12055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO72_12055	COG0519	Catalyzes the synthesis of GMP from XMP
OIO72_12060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO72_12085	COG0697	spore germination
OIO72_12090	COG1923	regulation of RNA biosynthetic process
OIO72_12100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIO72_12105	COG0802	atpase or kinase
OIO72_12125	COG1187	pseudouridine synthase activity
OIO72_12140	COG0583	DNA-binding transcription factor activity
OIO72_12155	COG2814	Major facilitator Superfamily
OIO72_12160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO72_12185	COG0729	surface antigen
OIO72_12205	COG0174	glutamine synthetase
OIO72_12210	COG0745	RESPONSE REGULATOR receiver
OIO72_12225	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIO72_12230	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIO72_12240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OIO72_12255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO72_12260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO72_12265	COG1960	acyl-CoA dehydrogenase activity
OIO72_12280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO72_12285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO72_12305	COG0583	DNA-binding transcription factor activity
OIO72_12320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO72_12330	COG3658	cytochrome
OIO72_12335	COG1215	transferase activity, transferring glycosyl groups
OIO72_12340	COG0726	polysaccharide deacetylase
OIO72_12340	COG1649	PFAM Uncharacterised BCR, COG1649
OIO72_12365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIO72_12370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIO72_12380	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OIO72_12405	COG0305	Participates in initiation and elongation during chromosome replication
OIO72_12410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIO72_12420	COG1305	Transglutaminase-like
OIO72_12430	COG2308	Evidence 4 Homologs of previously reported genes of
OIO72_12460	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OIO72_12465	COG0138	bifunctional purine biosynthesis protein purh
OIO72_12470	COG0151	Belongs to the GarS family
OIO72_12475	COG1464	Belongs to the NlpA lipoprotein family
OIO72_12480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO72_12485	COG2011	ABC-type metal ion transport system permease component
OIO72_12490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO72_12500	COG1301	dicarboxylic acid transport
OIO72_12530	COG1794	racemase activity, acting on amino acids and derivatives
OIO72_12540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIO72_12540	COG3008	intermembrane lipid transfer
OIO72_12545	COG2995	paraquat-inducible protein a
OIO72_12575	COG0477	Major facilitator Superfamily
OIO72_12585	COG2186	Transcriptional regulator
OIO72_12595	COG0786	glutamate:sodium symporter activity
OIO72_12600	COG3243	poly(R)-hydroxyalkanoic acid synthase
OIO72_12625	COG3111	PFAM Bacterial OB fold (BOF) protein
OIO72_12695	COG0515	serine threonine protein kinase
OIO72_12695	COG2815	serine threonine protein kinase
OIO72_12725	COG1610	YqeY-like protein
OIO72_12730	COG4783	chaperone-mediated protein folding
OIO72_12755	COG1286	toxin biosynthetic process
OIO72_12785	COG0778	Nitroreductase
OIO72_12795	COG0513	Belongs to the DEAD box helicase family
OIO72_12820	COG2363	Small membrane protein
OIO72_12850	COG4650	regulator
OIO72_12855	COG1234	tRNA 3'-trailer cleavage
OIO72_12860	COG1690	Belongs to the RtcB family
OIO72_12880	COG2195	Cleaves the N-terminal amino acid of tripeptides
OIO72_12890	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIO72_12900	COG2819	hydrolase of the alpha beta superfamily
OIO72_12905	COG1960	acyl-CoA dehydrogenase activity
OIO72_12910	COG1301	dicarboxylic acid transport
OIO72_12920	COG3139	Protein of unknown function (DUF1315)
OIO72_12925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIO72_12930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIO72_12940	COG0494	nUDIX hydrolase
OIO72_12950	COG0642	Histidine kinase
OIO72_12965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OIO72_12975	COG1720	tRNA m6t6A37 methyltransferase activity
OIO72_12990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO72_12995	COG0826	peptidase U32
OIO72_13000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO72_13010	COG4598	ABC transporter
OIO72_13015	COG4160	amino acid transport
OIO72_13020	COG4215	(ABC) transporter
OIO72_13035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO72_13080	COG1131	(ABC) transporter
OIO72_13085	COG0842	Transport permease protein
OIO72_13100	COG0772	Belongs to the SEDS family
OIO72_13105	COG2951	lytic endotransglycosylase activity
OIO72_13130	COG2207	Transcriptional regulator
OIO72_13145	COG0052	Belongs to the universal ribosomal protein uS2 family
OIO72_13150	COG0024	Methionine aminopeptidase
OIO72_13170	COG2223	nitrite transmembrane transporter activity
OIO72_13180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO72_13185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO72_13190	COG1960	acyl-CoA dehydrogenase activity
OIO72_13205	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIO72_13210	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIO72_13215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO72_13235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO72_13240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIO72_13245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIO72_13280	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OIO72_13290	COG0174	glutamine synthetase
OIO72_13305	COG0512	Glutamine amidotransferase of anthranilate synthase
OIO72_13310	COG0308	aminopeptidase N
OIO72_13340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIO72_13350	COG0302	gtp cyclohydrolase
OIO72_13370	COG3739	integral membrane protein
OIO72_13390	COG2977	Belongs to the P-Pant transferase superfamily
OIO72_13395	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OIO72_13400	COG1132	(ABC) transporter
OIO72_13405	COG1132	(ABC) transporter
OIO72_13420	COG3433	isochorismatase activity
OIO72_13420	COG1535	isochorismatase
OIO72_13425	COG1021	2,3-dihydroxybenzoate-AMP ligase
OIO72_13430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO72_13440	COG4774	siderophore transport
OIO72_13445	COG4607	ABC-type enterochelin transport system periplasmic component
OIO72_13450	COG4604	ABC transporter, ATP-binding protein
OIO72_13455	COG4605	iron ion homeostasis
OIO72_13460	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO72_13470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO72_13485	COG2964	Protein conserved in bacteria
OIO72_13495	COG1741	Belongs to the pirin family
OIO72_13525	COG2130	NADP-dependent
OIO72_13535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO72_13545	COG0596	Alpha beta hydrolase
OIO72_13560	COG0583	DNA-binding transcription factor activity
OIO72_13565	COG1335	isochorismatase
OIO72_13605	COG2879	small protein
OIO72_13610	COG1966	Carbon starvation protein
OIO72_13630	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OIO72_13655	COG1067	ATP-dependent peptidase activity
OIO72_13660	COG0583	DNA-binding transcription factor activity
OIO72_13685	COG1686	Belongs to the peptidase S11 family
OIO72_13690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OIO72_13725	COG0616	signal peptide processing
OIO72_13730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIO72_13740	COG0573	inorganic phosphate transmembrane transporter activity
OIO72_13745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIO72_13750	COG1113	amino acid transport
OIO72_13755	COG3961	Belongs to the TPP enzyme family
OIO72_13760	COG1522	sequence-specific DNA binding
OIO72_13770	COG0076	glutamate decarboxylase activity
OIO72_13775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO72_13785	COG1309	transcriptional regulator
OIO72_13800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO72_13835	COG0352	thiamine-phosphate diphosphorylase activity
OIO72_13860	COG0612	Peptidase, M16
OIO72_13870	COG1823	symporter activity
OIO72_13875	COG0583	DNA-binding transcription factor activity
OIO72_13880	COG0477	Major facilitator Superfamily
OIO72_13905	COG0582	viral genome integration into host DNA
OIO72_14040	COG4695	Portal protein
OIO72_14240	COG1187	pseudouridine synthase activity
OIO72_14255	COG1686	Belongs to the peptidase S11 family
OIO72_14260	COG1252	NADH dehydrogenase
OIO72_14275	COG2070	2-Nitropropane dioxygenase
OIO72_14330	COG0556	nucleotide-excision repair
OIO72_14350	COG0436	Aminotransferase
OIO72_14360	COG0443	Heat shock 70 kDa protein
OIO72_14390	COG4221	oxidoreductase activity
OIO72_14400	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OIO72_14405	COG1381	Involved in DNA repair and RecF pathway recombination
OIO72_14415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIO72_14430	COG0681	Belongs to the peptidase S26 family
OIO72_14440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIO72_14450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO72_14470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIO72_14475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIO72_14480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OIO72_14490	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIO72_14495	COG4208	sulfate ABC transporter
OIO72_14500	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OIO72_14505	COG0583	DNA-binding transcription factor activity
OIO72_14510	COG4625	pathogenesis
OIO72_14525	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OIO72_14540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OIO72_14550	COG1056	cytidyltransferase-related domain
OIO72_14550	COG1051	belongs to the nudix hydrolase family
OIO72_14555	COG1024	Enoyl-CoA hydratase
OIO72_14570	COG2814	Major facilitator Superfamily
OIO72_14575	COG0047	phosphoribosylformylglycinamidine synthase activity
OIO72_14575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIO72_14595	COG1473	amidohydrolase
OIO72_14600	COG0824	Thioesterase
OIO72_14620	COG0823	Involved in the tonB-independent uptake of proteins
OIO72_14640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO72_14675	COG0628	permease
OIO72_14685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIO72_14690	COG0596	Alpha beta hydrolase
OIO72_14695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIO72_14695	COG0616	signal peptide processing
OIO72_14705	COG0658	competence protein
OIO72_14705	COG2333	competence protein COMEC
OIO72_14710	COG1136	(ABC) transporter
OIO72_14715	COG4591	ABC-type transport system involved in lipoprotein release permease component
OIO72_14750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO72_14770	COG0463	Glycosyl transferase, family 2
OIO72_14800	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO72_14805	COG1280	lysine exporter protein (LysE YggA)
OIO72_14810	COG2267	carboxylic ester hydrolase activity
OIO72_14820	COG0019	diaminopimelate decarboxylase activity
OIO72_14830	COG1113	amino acid transport
OIO72_14845	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OIO72_14855	COG3339	Conserved Protein
OIO72_14860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIO72_14865	COG0243	molybdopterin cofactor binding
OIO72_14870	COG1929	Belongs to the glycerate kinase type-1 family
OIO72_14885	COG0778	Nitroreductase
OIO72_14910	COG3811	Belongs to the UPF0386 family
OIO72_14935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO72_14950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIO72_14970	COG0741	lytic transglycosylase activity
OIO72_14990	COG0584	glycerophosphoryl diester phosphodiesterase
OIO72_14995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO72_15020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO72_15025	COG1597	lipid kinase activity
OIO72_15040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIO72_15045	COG0477	Major facilitator Superfamily
OIO72_15095	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIO72_15100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO72_15125	COG0505	Belongs to the CarA family
OIO72_15145	COG0589	response to stress
OIO72_15160	COG2843	Capsule synthesis protein
OIO72_15180	COG2321	neutral zinc metallopeptidase
OIO72_15185	COG2354	Protein conserved in bacteria
OIO72_15205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO72_15230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIO72_15235	COG1053	succinate dehydrogenase
OIO72_15240	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OIO72_15245	COG2009	succinate dehydrogenase
OIO72_15280	COG2921	Belongs to the UPF0250 family
OIO72_15285	COG0321	lipoyl(octanoyl) transferase activity
OIO72_15300	COG0531	amino acid
OIO72_15310	COG1733	regulation of RNA biosynthetic process
OIO72_15315	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIO72_15320	COG1648	precorrin-2 dehydrogenase activity
OIO72_15320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIO72_15335	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OIO72_15370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO72_15380	COG1538	Outer membrane efflux protein
OIO72_15385	COG0393	Putative heavy-metal-binding
OIO72_15390	COG0393	Putative heavy-metal-binding
OIO72_15400	COG1028	Short-chain dehydrogenase reductase Sdr
OIO72_15410	COG0525	valine-tRNA ligase activity
OIO72_15430	COG0583	DNA-binding transcription factor activity
OIO72_15435	COG0004	ammonium transporteR
OIO72_15450	COG0642	Histidine kinase
OIO72_15455	COG0745	RESPONSE REGULATOR receiver
OIO72_15460	COG2194	sulfuric ester hydrolase activity
OIO72_15480	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO72_15495	COG2315	Protein conserved in bacteria
OIO72_15500	COG0142	geranyltranstransferase activity
OIO72_15505	COG2828	Protein conserved in bacteria
OIO72_15510	COG1113	amino acid transport
OIO72_15555	COG2207	Transcriptional regulator
OIO72_15580	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO72_15590	COG0560	Phosphoserine phosphatase
OIO72_15600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO72_15610	COG1530	ribonuclease E activity
OIO72_15615	COG0424	maF-like protein
OIO72_15620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OIO72_15625	COG1792	Involved in formation and maintenance of cell shape
OIO72_15630	COG1077	Cell shape determining protein MreB Mrl
OIO72_15635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO72_15645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO72_15670	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OIO72_15675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO72_15680	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO72_15685	COG1115	amino acid carrier protein
OIO72_15705	COG2814	Major facilitator Superfamily
OIO72_15710	COG1289	transmembrane transporter activity
OIO72_15720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OIO72_15770	COG1376	ErfK ybiS ycfS ynhG family protein
OIO72_15775	COG2832	Protein of unknown function (DUF454)
OIO72_15785	COG5510	response to toxic substance
OIO72_15810	COG0840	transmembrane signaling receptor activity
OIO72_15850	COG3422	double-strand break repair
OIO72_15855	COG2824	Alkylphosphonate utilization operon protein PhnA
OIO72_15860	COG3189	MarR family transcriptional regulator
OIO72_15870	COG0354	folic acid binding
OIO72_15875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO72_15885	COG0679	Auxin Efflux Carrier
OIO72_15890	COG1902	pentaerythritol trinitrate reductase activity
OIO72_15895	COG4772	TonB-dependent receptor
OIO72_15900	COG2094	Belongs to the DNA glycosylase MPG family
OIO72_15925	COG1217	gtp-binding protein TYPA
OIO72_15930	COG2233	PERMEase
OIO72_15940	COG0833	amino acid
OIO72_15945	COG1690	Belongs to the RtcB family
OIO72_15955	COG2885	chlorophyll binding
OIO72_15955	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OIO72_15965	COG0183	Belongs to the thiolase family
OIO72_15985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO72_16005	COG2207	Transcriptional regulator
OIO72_16010	COG0183	Belongs to the thiolase family
OIO72_16040	COG1272	protein, Hemolysin III
OIO72_16045	COG0477	Major facilitator Superfamily
OIO72_16060	COG0450	alkyl hydroperoxide reductase
OIO72_16080	COG0285	dihydrofolate synthase activity
OIO72_16130	COG2096	Adenosyltransferase
OIO72_16135	COG0584	glycerophosphoryl diester phosphodiesterase
OIO72_16150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OIO72_16155	COG0745	RESPONSE REGULATOR receiver
OIO72_16160	COG2205	protein histidine kinase activity
OIO72_16170	COG1960	acyl-CoA dehydrogenase activity
OIO72_16175	COG1960	acyl-CoA dehydrogenase activity
OIO72_16240	COG0438	transferase activity, transferring glycosyl groups
OIO72_16245	COG0463	Glycosyl transferase, family 2
OIO72_16250	COG0726	polysaccharide deacetylase
OIO72_16270	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIO72_16275	COG2205	protein histidine kinase activity
OIO72_16305	COG1862	Preprotein translocase
OIO72_16315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIO72_16320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIO72_16330	COG3781	membrane
OIO72_16335	COG0613	PHP domain protein
OIO72_16345	COG2350	Protein conserved in bacteria
OIO72_16375	COG1607	acyl-coa hydrolase
OIO72_16435	COG2199	diguanylate cyclase activity
OIO72_16445	COG1408	metallophosphoesterase
OIO72_16450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO72_16460	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIO72_16480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIO72_16485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIO72_16490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OIO72_16500	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIO72_16510	COG2969	positive regulation of protein catabolic process
OIO72_16530	COG1960	acyl-CoA dehydrogenase activity
OIO72_16535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO72_16550	COG1309	transcriptional regulator
OIO72_16555	COG1960	acyl-CoA dehydrogenase activity
OIO72_16600	COG1183	phosphatidylcholine synthase activity
OIO72_16605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OIO72_16635	COG0741	lytic transglycosylase activity
OIO72_16635	COG0739	heme binding
OIO72_16635	COG1196	nuclear chromosome segregation
OIO72_16645	COG1702	phosphate starvation-inducible protein PhoH
OIO72_16680	COG1295	ribonuclease BN
OIO72_16685	COG0697	spore germination
OIO72_16690	COG2169	Transcriptional regulator
OIO72_16695	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO72_16740	COG0557	exoribonuclease II activity
OIO72_16745	COG0339	signal peptide processing
OIO72_16750	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OIO72_16780	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OIO72_16785	COG1960	acyl-CoA dehydrogenase activity
OIO72_16950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO72_16950	COG1017	nitric oxide dioxygenase activity
OIO72_16955	COG1959	2 iron, 2 sulfur cluster binding
OIO72_16970	COG1301	dicarboxylic acid transport
OIO72_16975	COG1946	Acyl-CoA thioesterase
OIO72_16995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIO72_17000	COG1040	competence protein
OIO72_17005	COG0494	nUDIX hydrolase
OIO72_17015	COG0598	Magnesium transport protein CorA
OIO72_17025	COG2854	intermembrane phospholipid transfer
OIO72_17035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIO72_17040	COG1127	ABC transporter
OIO72_17050	COG0513	Belongs to the DEAD box helicase family
OIO72_17070	COG0408	coproporphyrinogen oxidase activity
OIO72_17085	COG1960	acyl-CoA dehydrogenase activity
OIO72_17095	COG1983	PspC domain protein
OIO72_17100	COG0517	IMP dehydrogenase activity
OIO72_17125	COG0752	glycyl-tRNA synthetase alpha subunit
OIO72_17150	COG0583	DNA-binding transcription factor activity
OIO72_17190	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_17200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO72_17205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO72_17210	COG0833	amino acid
OIO72_17240	COG1192	Involved in chromosome partitioning
OIO72_17245	COG0628	permease
OIO72_17255	COG1289	transmembrane transporter activity
OIO72_17270	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO72_17275	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OIO72_17285	COG0277	FAD linked oxidase domain protein
OIO72_17290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIO72_17315	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIO72_17320	COG5380	lipid catabolic process
OIO72_17340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIO72_17395	COG0194	GDP metabolic process
OIO72_17410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO72_17430	COG3307	-O-antigen
OIO72_17445	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OIO72_17450	COG1704	LemA family
OIO72_17460	COG0493	'glutamate synthase
OIO72_17465	COG0070	glutamate synthase
OIO72_17465	COG0069	glutamate synthase activity
OIO72_17465	COG0067	glutamate synthase
OIO72_17515	COG2226	methyltransferase
OIO72_17530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIO72_17535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIO72_17580	COG0833	amino acid
OIO72_17645	COG0488	(ABC) transporter
OIO72_17650	COG2873	o-acetylhomoserine
OIO72_17655	COG4221	oxidoreductase activity
OIO72_17660	COG0659	secondary active sulfate transmembrane transporter activity
OIO72_17685	COG0427	acetyl-CoA hydrolase
OIO72_17715	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIO72_17735	COG1132	(ABC) transporter
OIO72_17750	COG2329	Antibiotic biosynthesis monooxygenase
OIO72_17765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OIO72_17830	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO72_17835	COG1733	regulation of RNA biosynthetic process
OIO72_17870	COG0667	Aldo Keto reductase
OIO72_17890	COG1309	transcriptional regulator
OIO72_17905	COG0583	DNA-binding transcription factor activity
OIO72_17910	COG2814	Major facilitator Superfamily
OIO72_17945	COG1335	isochorismatase
OIO72_17955	COG1012	belongs to the aldehyde dehydrogenase family
OIO72_17960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO72_17970	COG1113	amino acid transport
OIO72_17980	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO72_18020	COG2814	Major facilitator Superfamily
OIO72_18030	COG0352	thiamine-phosphate diphosphorylase activity
OIO72_18030	COG0351	phosphomethylpyrimidine kinase
OIO72_18030	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO72_18050	COG1309	transcriptional regulator
OIO72_18055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIO72_18075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO72_18085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO72_18090	COG3162	membrane
OIO72_18095	COG0784	Response regulator, receiver
OIO72_18095	COG2205	protein histidine kinase activity
OIO72_18095	COG2198	Histidine kinase
OIO72_18120	COG1522	sequence-specific DNA binding
OIO72_18125	COG1335	isochorismatase
OIO72_18130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO72_18140	COG0668	transmembrane transport
OIO72_18145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO72_18150	COG1519	Transferase
OIO72_18155	COG1902	pentaerythritol trinitrate reductase activity
OIO72_18180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OIO72_18205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO72_18205	COG0426	domain, Protein
OIO72_18210	COG4774	siderophore transport
OIO72_18215	COG2119	membrane
OIO72_18225	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO72_18235	COG4942	peptidase
OIO72_18250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIO72_18260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIO72_18280	COG0189	ligase activity
OIO72_18300	COG0708	Exodeoxyribonuclease III
OIO72_18305	COG1393	Belongs to the ArsC family
OIO72_18320	COG3706	GGDEF domain
OIO72_18355	COG2351	hydroxyisourate hydrolase activity
OIO72_18360	COG2233	PERMEase
OIO72_18370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO72_18380	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OIO72_18390	COG3150	esterase
OIO72_18415	COG2918	glutathione biosynthetic process
OIO72_18430	COG2733	membrane
OIO72_18435	COG0436	Aminotransferase
OIO72_18440	COG0534	Mate efflux family protein
OIO72_18525	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OIO72_18530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OIO72_18540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIO72_18565	COG1280	lysine exporter protein (LysE YggA)
OIO72_18585	COG0010	Belongs to the arginase family
OIO72_18615	COG2188	Transcriptional regulator
OIO72_18625	COG0523	cobalamin synthesis protein
OIO72_18635	COG1113	amino acid transport
OIO72_18645	COG0625	glutathione transferase activity
OIO72_18665	COG1683	Conserved Protein
OIO72_18670	COG0534	Mate efflux family protein
OIO72_18675	COG0385	Bile acid
OIO72_18680	COG1335	isochorismatase
OIO72_18685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO72_18705	COG2116	formate transmembrane transporter activity
OIO72_18710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OIO72_18725	COG3188	usher protein
OIO72_18730	COG3121	Chaperone
OIO72_18740	COG2983	Belongs to the UPF0260 family
OIO72_18760	COG1194	a g-specific adenine glycosylase
OIO72_18775	COG2818	Glycosylase
OIO72_18780	COG1064	alcohol dehydrogenase
OIO72_18785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO72_18800	COG0583	DNA-binding transcription factor activity
OIO72_18805	COG0656	L-ascorbic acid biosynthetic process
OIO72_18810	COG2814	Major facilitator Superfamily
OIO72_18845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO72_18860	COG2233	PERMEase
OIO72_18900	COG0733	neurotransmitter:sodium symporter activity
OIO72_18940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIO72_18945	COG0657	acetylesterase activity
OIO72_18965	COG0583	DNA-binding transcription factor activity
OIO72_18995	COG2951	lytic endotransglycosylase activity
OIO72_19000	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIO72_19015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIO72_19025	COG0671	phosphoesterase, PA-phosphatase related
OIO72_19030	COG0861	Integral membrane protein TerC family
OIO72_19040	COG0754	glutathionylspermidine amidase activity
OIO72_19050	COG0402	S-adenosylhomocysteine deaminase activity
OIO72_19065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO72_19070	COG1230	cation diffusion facilitator family transporter
OIO72_19085	COG0706	membrane insertase activity
OIO72_19140	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
OIO72_19145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde