locus-tag	class	description
OIO44_00010	COG0592	DNA-directed DNA polymerase activity
OIO44_00020	COG0187	DNA topoisomerase II activity
OIO44_00030	COG0586	Pfam SNARE associated Golgi protein
OIO44_00035	COG0488	(ABC) transporter
OIO44_00060	COG0596	Alpha beta hydrolase
OIO44_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OIO44_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO44_00110	COG0733	neurotransmitter:sodium symporter activity
OIO44_00150	COG2233	PERMEase
OIO44_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO44_00200	COG2814	Major facilitator Superfamily
OIO44_00205	COG0656	L-ascorbic acid biosynthetic process
OIO44_00210	COG0583	DNA-binding transcription factor activity
OIO44_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO44_00230	COG1064	alcohol dehydrogenase
OIO44_00235	COG2818	Glycosylase
OIO44_00250	COG1194	a g-specific adenine glycosylase
OIO44_00270	COG2983	Belongs to the UPF0260 family
OIO44_00275	COG2133	pyrroloquinoline quinone binding
OIO44_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OIO44_00285	COG2116	formate transmembrane transporter activity
OIO44_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO44_00310	COG1335	isochorismatase
OIO44_00320	COG0534	Mate efflux family protein
OIO44_00325	COG1683	Conserved Protein
OIO44_00345	COG0625	glutathione transferase activity
OIO44_00355	COG1113	amino acid transport
OIO44_00365	COG0523	cobalamin synthesis protein
OIO44_00375	COG2188	Transcriptional regulator
OIO44_00405	COG0010	Belongs to the arginase family
OIO44_00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO44_00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIO44_00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OIO44_00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OIO44_00545	COG0534	Mate efflux family protein
OIO44_00550	COG0436	Aminotransferase
OIO44_00555	COG2733	membrane
OIO44_00570	COG2918	glutathione biosynthetic process
OIO44_00600	COG3150	esterase
OIO44_00610	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_00615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OIO44_00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO44_00635	COG2233	PERMEase
OIO44_00640	COG2351	hydroxyisourate hydrolase activity
OIO44_00675	COG3706	GGDEF domain
OIO44_00690	COG1393	Belongs to the ArsC family
OIO44_00695	COG0708	Exodeoxyribonuclease III
OIO44_00730	COG0589	response to stress
OIO44_00735	COG0659	secondary active sulfate transmembrane transporter activity
OIO44_00795	COG0347	Belongs to the P(II) protein family
OIO44_00800	COG0004	ammonium transporteR
OIO44_00810	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO44_00810	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO44_00850	COG0795	lipopolysaccharide-transporting ATPase activity
OIO44_00855	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIO44_00860	COG0793	Belongs to the peptidase S41A family
OIO44_00875	COG2197	response regulator
OIO44_00885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIO44_00895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO44_00900	COG4974	Belongs to the 'phage' integrase family
OIO44_00925	COG0772	Belongs to the SEDS family
OIO44_00930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO44_00935	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OIO44_00940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO44_00965	COG0697	spore germination
OIO44_00970	COG1538	Outer membrane efflux protein
OIO44_00990	COG3275	phosphorelay sensor kinase activity
OIO44_01000	COG0181	hydroxymethylbilane synthase activity
OIO44_01045	COG1716	ATPase activity
OIO44_01050	COG0546	phosphoglycolate phosphatase activity
OIO44_01145	COG0596	Alpha beta hydrolase
OIO44_01150	COG2056	Na+-H+ antiporter family
OIO44_01165	COG0326	Molecular chaperone. Has ATPase activity
OIO44_01180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIO44_01245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIO44_01250	COG2169	Transcriptional regulator
OIO44_01250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO44_01280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIO44_01290	COG0497	DNA recombination
OIO44_01305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO44_01315	COG0237	dephospho-CoA kinase activity
OIO44_01365	COG0195	Participates in both transcription termination and antitermination
OIO44_01380	COG1320	monovalent cation:proton antiporter activity
OIO44_01385	COG2212	antiporter activity
OIO44_01390	COG1863	multisubunit Na H antiporter MnhE subunit
OIO44_01395	COG0651	ATP synthesis coupled electron transport
OIO44_01400	COG1006	Multisubunit Na H antiporter MnhC subunit
OIO44_01405	COG2111	Na H antiporter
OIO44_01405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO44_01420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIO44_01425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO44_01440	COG2226	methyltransferase
OIO44_01460	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OIO44_01465	COG1074	ATP-dependent DNA helicase activity
OIO44_01470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO44_01475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO44_01490	COG0598	Magnesium transport protein CorA
OIO44_01495	COG0789	Transcriptional regulator
OIO44_01500	COG0484	heat shock protein binding
OIO44_01510	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OIO44_01515	COG0475	glutathione-regulated potassium exporter activity
OIO44_01515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO44_01520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIO44_01540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO44_01550	COG4535	Mg2 and Co2 transporter CorC
OIO44_01555	COG0425	Belongs to the sulfur carrier protein TusA family
OIO44_01560	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OIO44_01560	COG0644	oxidoreductase
OIO44_01570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO44_01585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO44_01590	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OIO44_01630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OIO44_01645	COG0534	Mate efflux family protein
OIO44_01655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIO44_01660	COG4221	oxidoreductase activity
OIO44_01665	COG0583	DNA-binding transcription factor activity
OIO44_01680	COG0318	PFAM AMP-dependent synthetase and ligase
OIO44_01685	COG1530	ribonuclease E activity
OIO44_01695	COG0546	phosphoglycolate phosphatase activity
OIO44_01700	COG2378	regulation of single-species biofilm formation
OIO44_01705	COG0625	glutathione transferase activity
OIO44_01715	COG0583	DNA-binding transcription factor activity
OIO44_01780	COG0473	3-isopropylmalate dehydrogenase activity
OIO44_01835	COG1301	dicarboxylic acid transport
OIO44_01845	COG1560	Kdo2-lipid A biosynthetic process
OIO44_01850	COG1280	lysine exporter protein (LysE YggA)
OIO44_01855	COG0488	(ABC) transporter
OIO44_01860	COG2900	Belongs to the SlyX family
OIO44_01870	COG1733	regulation of RNA biosynthetic process
OIO44_01895	COG0210	DNA helicase
OIO44_01900	COG0724	RNA recognition motif
OIO44_01920	COG4651	solute:proton antiporter activity
OIO44_01920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO44_01945	COG0788	formyltetrahydrofolate deformylase activity
OIO44_02045	COG2813	Specifically methylates the guanine in position
OIO44_02045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO44_02055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO44_02065	COG4774	siderophore transport
OIO44_02075	COG0740	serine-type endopeptidase activity
OIO44_02095	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO44_02095	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO44_02100	COG0857	belongs to the CobB CobQ family
OIO44_02100	COG0280	phosphate acetyltransferase
OIO44_02105	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIO44_02115	COG0800	Aldolase
OIO44_02125	COG3265	gluconokinase activity
OIO44_02140	COG2267	carboxylic ester hydrolase activity
OIO44_02155	COG0793	Belongs to the peptidase S41A family
OIO44_02190	COG1426	Protein conserved in bacteria
OIO44_02235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO44_02245	COG0318	PFAM AMP-dependent synthetase and ligase
OIO44_02260	COG2986	histidine ammonia-lyase
OIO44_02300	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_02305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OIO44_02325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OIO44_02335	COG1162	GTPase activity
OIO44_02340	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIO44_02355	COG1538	Outer membrane efflux protein
OIO44_02360	COG1136	(ABC) transporter
OIO44_02360	COG0577	efflux transmembrane transporter activity
OIO44_02365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO44_02390	COG0028	Belongs to the TPP enzyme family
OIO44_02395	COG0440	acetolactate synthase activity
OIO44_02425	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIO44_02440	COG0084	hydrolase, TatD family'
OIO44_02455	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OIO44_02465	COG0583	DNA-binding transcription factor activity
OIO44_02475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO44_02480	COG2814	Major facilitator Superfamily
OIO44_02490	COG0697	spore germination
OIO44_02520	COG3622	Belongs to the hyi family
OIO44_02525	COG2084	Dehydrogenase
OIO44_02530	COG1024	Enoyl-CoA hydratase
OIO44_02535	COG2205	protein histidine kinase activity
OIO44_02535	COG5002	protein histidine kinase activity
OIO44_02535	COG0784	Response regulator, receiver
OIO44_02555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO44_02565	COG3956	TIGRFAM MazG family protein
OIO44_02570	COG1555	photosystem II stabilization
OIO44_02575	COG0617	tRNA 3'-terminal CCA addition
OIO44_02580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OIO44_02600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO44_02605	COG3028	Belongs to the UPF0307 family
OIO44_02610	COG0318	PFAM AMP-dependent synthetase and ligase
OIO44_02625	COG0625	glutathione transferase activity
OIO44_02630	COG1238	metal cluster binding
OIO44_02675	COG0072	phenylalanine-tRNA ligase activity
OIO44_02705	COG0248	Ppx GppA phosphatase
OIO44_02715	COG0037	tRNA processing
OIO44_02755	COG1764	response to oxidative stress
OIO44_02760	COG1846	Transcriptional regulator
OIO44_02830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIO44_02835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIO44_02840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIO44_02850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OIO44_02900	COG1214	PFAM Peptidase M22, glycoprotease
OIO44_02925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIO44_02930	COG0561	phosphatase activity
OIO44_02940	COG2132	Multicopper oxidase
OIO44_02945	COG3667	copper resistance
OIO44_02960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO44_02965	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIO44_02970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIO44_03000	COG1063	alcohol dehydrogenase
OIO44_03005	COG0583	DNA-binding transcription factor activity
OIO44_03010	COG1960	acyl-CoA dehydrogenase activity
OIO44_03015	COG2814	Major facilitator Superfamily
OIO44_03020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO44_03030	COG1053	succinate dehydrogenase
OIO44_03035	COG0583	DNA-binding transcription factor activity
OIO44_03050	COG0583	DNA-binding transcription factor activity
OIO44_03080	COG0583	DNA-binding transcription factor activity
OIO44_03095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO44_03120	COG0384	phenazine biosynthesis protein PhzF
OIO44_03145	COG4993	Dehydrogenase
OIO44_03215	COG2205	protein histidine kinase activity
OIO44_03225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO44_03245	COG0745	RESPONSE REGULATOR receiver
OIO44_03285	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIO44_03315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO44_03320	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIO44_03340	COG0583	DNA-binding transcription factor activity
OIO44_03360	COG0668	transmembrane transport
OIO44_03370	COG2081	HI0933 family
OIO44_03375	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO44_03405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO44_03405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO44_03415	COG0489	protein tyrosine kinase activity
OIO44_03465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO44_03475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIO44_03490	COG0730	response to heat
OIO44_03500	COG1196	nuclear chromosome segregation
OIO44_03520	COG2223	nitrite transmembrane transporter activity
OIO44_03525	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OIO44_03530	COG1877	trehalose-phosphatase activity
OIO44_03535	COG0596	Alpha beta hydrolase
OIO44_03535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO44_03535	COG2226	methyltransferase
OIO44_03550	COG4106	trans-aconitate 2-methyltransferase activity
OIO44_03565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIO44_03570	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIO44_03575	COG0009	L-threonylcarbamoyladenylate synthase
OIO44_03580	COG3101	peptidyl-lysine hydroxylation
OIO44_03585	COG1399	metal-binding, possibly nucleic acid-binding protein
OIO44_03610	COG1652	LysM domain
OIO44_03615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO44_03615	COG0352	thiamine-phosphate diphosphorylase activity
OIO44_03615	COG0351	phosphomethylpyrimidine kinase
OIO44_03625	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIO44_03655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO44_03685	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OIO44_03700	COG0358	DNA primase activity
OIO44_03710	COG0564	pseudouridine synthase activity
OIO44_03735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO44_03755	COG0583	DNA-binding transcription factor activity
OIO44_03760	COG0473	3-isopropylmalate dehydrogenase activity
OIO44_03770	COG0657	acetylesterase activity
OIO44_03780	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_03800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIO44_03800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO44_03815	COG1981	membrane
OIO44_03860	COG0456	acetyltransferase
OIO44_03870	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OIO44_03875	COG0492	ferredoxin-NADP+ reductase activity
OIO44_03880	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OIO44_03880	COG1674	ftsk spoiiie
OIO44_03885	COG1280	lysine exporter protein (LysE YggA)
OIO44_03910	COG2894	cell division
OIO44_03925	COG0204	Acyl-transferase
OIO44_03930	COG2885	chlorophyll binding
OIO44_03935	COG0210	DNA helicase
OIO44_03945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO44_03960	COG0121	glutamine amidotransferase
OIO44_03980	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO44_03985	COG0735	belongs to the Fur family
OIO44_04010	COG0420	3'-5' exonuclease activity
OIO44_04030	COG1090	epimerase
OIO44_04045	COG2050	protein possibly involved in aromatic compounds catabolism
OIO44_04055	COG2814	Major facilitator Superfamily
OIO44_04060	COG0405	Gamma-glutamyltransferase
OIO44_04130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO44_04215	COG1484	DNA-dependent DNA replication
OIO44_04435	COG2026	Addiction module toxin, RelE StbE family
OIO44_04475	COG0592	DNA-directed DNA polymerase activity
OIO44_04560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO44_04580	COG0582	viral genome integration into host DNA
OIO44_04625	COG0629	single-stranded DNA binding
OIO44_04690	COG0477	Major facilitator Superfamily
OIO44_04695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO44_04705	COG1595	DNA-templated transcription, initiation
OIO44_04760	COG0531	amino acid
OIO44_04765	COG2040	homocysteine
OIO44_04790	COG1309	transcriptional regulator
OIO44_04795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO44_04800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO44_04810	COG1607	acyl-coa hydrolase
OIO44_04820	COG0523	cobalamin synthesis protein
OIO44_04830	COG4681	YaeQ
OIO44_04840	COG0726	polysaccharide deacetylase
OIO44_04840	COG1649	PFAM Uncharacterised BCR, COG1649
OIO44_04845	COG1215	transferase activity, transferring glycosyl groups
OIO44_04870	COG1414	Transcriptional regulator
OIO44_04890	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_04900	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO44_04905	COG2271	Major facilitator Superfamily
OIO44_04915	COG2267	carboxylic ester hydrolase activity
OIO44_04920	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_04935	COG0028	Belongs to the TPP enzyme family
OIO44_04945	COG0477	Major facilitator Superfamily
OIO44_04950	COG0242	peptide deformylase activity
OIO44_04955	COG2066	Belongs to the glutaminase family
OIO44_04960	COG2207	Transcriptional regulator
OIO44_04965	COG2223	nitrite transmembrane transporter activity
OIO44_04980	COG0583	DNA-binding transcription factor activity
OIO44_04985	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_04990	COG2271	Major facilitator Superfamily
OIO44_04995	COG3959	Transketolase, thiamine diphosphate binding domain
OIO44_05000	COG3958	Transketolase
OIO44_05010	COG0306	phosphate transporter
OIO44_05030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIO44_05085	COG4181	ATPase activity
OIO44_05090	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OIO44_05115	COG0583	DNA-binding transcription factor activity
OIO44_05125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO44_05130	COG1773	rubredoxin
OIO44_05180	COG2851	Citrate transporter
OIO44_05185	COG1253	flavin adenine dinucleotide binding
OIO44_05225	COG0804	urea catabolic process
OIO44_05235	COG0830	nickel cation binding
OIO44_05250	COG0742	ribosomal rna small subunit methyltransferase
OIO44_05255	COG0768	penicillin binding
OIO44_05280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIO44_05285	COG2878	Part of a membrane complex involved in electron transport
OIO44_05330	COG0589	response to stress
OIO44_05335	COG0659	secondary active sulfate transmembrane transporter activity
OIO44_05345	COG1002	Type II restriction enzyme, methylase subunits
OIO44_05350	COG1061	Type III restriction enzyme res subunit
OIO44_05385	COG3384	dioxygenase
OIO44_05410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIO44_05735	COG0739	heme binding
OIO44_05780	COG2194	sulfuric ester hydrolase activity
OIO44_05820	COG0006	proline dipeptidase activity
OIO44_05825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO44_05830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO44_05850	COG1279	arginine transmembrane transporter activity
OIO44_05855	COG0583	DNA-binding transcription factor activity
OIO44_05895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO44_05900	COG1388	LysM domain
OIO44_05900	COG0741	lytic transglycosylase activity
OIO44_05900	COG0741	lytic transglycosylase activity
OIO44_05900	COG1388	LysM domain
OIO44_05910	COG4174	ABC transporter (Permease)
OIO44_05915	COG4239	(ABC) transporter, permease
OIO44_05920	COG4172	Belongs to the ABC transporter superfamily
OIO44_05950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO44_05960	COG4251	negative regulation of phosphorylation
OIO44_05960	COG5001	Diguanylate cyclase
OIO44_05960	COG2203	Gaf domain
OIO44_05960	COG3706	GGDEF domain
OIO44_05970	COG1902	pentaerythritol trinitrate reductase activity
OIO44_05970	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO44_05985	COG4269	membrane
OIO44_06035	COG1061	Type III restriction enzyme res subunit
OIO44_06040	COG1002	Type II restriction enzyme, methylase subunits
OIO44_06050	COG0659	secondary active sulfate transmembrane transporter activity
OIO44_06055	COG0589	response to stress
OIO44_06125	COG2072	flavoprotein involved in K transport
OIO44_06135	COG2252	PERMEase
OIO44_06140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIO44_06145	COG3038	cytochrome b561
OIO44_06155	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIO44_06165	COG0527	aspartate kinase activity
OIO44_06175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIO44_06185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIO44_06200	COG0667	Aldo Keto reductase
OIO44_06215	COG1765	OsmC-like protein
OIO44_06230	COG0542	response to heat
OIO44_06265	COG2885	chlorophyll binding
OIO44_06275	COG0625	glutathione transferase activity
OIO44_06280	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIO44_06300	COG3634	alkyl hydroperoxide reductase activity
OIO44_06310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIO44_06320	COG0450	alkyl hydroperoxide reductase
OIO44_06325	COG1643	Atp-dependent helicase
OIO44_06340	COG2814	Major facilitator Superfamily
OIO44_06345	COG3135	benzoate transporter
OIO44_06350	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_06355	COG0543	2 iron, 2 sulfur cluster binding
OIO44_06355	COG0633	Ferredoxin
OIO44_06360	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO44_06365	COG4638	Rieske (2fe-2S)
OIO44_06375	COG0583	DNA-binding transcription factor activity
OIO44_06425	COG1570	exodeoxyribonuclease VII activity
OIO44_06455	COG1280	lysine exporter protein (LysE YggA)
OIO44_06460	COG1278	Cold shock
OIO44_06495	COG2814	Major facilitator Superfamily
OIO44_06530	COG0517	IMP dehydrogenase activity
OIO44_06530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OIO44_06535	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OIO44_06545	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OIO44_06550	COG1137	ATPase activity
OIO44_06555	COG1538	Outer membrane efflux protein
OIO44_06585	COG4122	O-methyltransferase activity
OIO44_06595	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OIO44_06610	COG1522	sequence-specific DNA binding
OIO44_06615	COG5006	permease, DMT superfamily
OIO44_06625	COG1560	Kdo2-lipid A biosynthetic process
OIO44_06640	COG2814	Major facilitator Superfamily
OIO44_06660	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO44_06710	COG0583	DNA-binding transcription factor activity
OIO44_06715	COG1914	H( )-stimulated, divalent metal cation uptake system
OIO44_06735	COG4770	biotin carboxylase activity
OIO44_06740	COG0038	chloride channel
OIO44_06760	COG1309	transcriptional regulator
OIO44_06770	COG1063	alcohol dehydrogenase
OIO44_06785	COG0439	Biotin carboxylase
OIO44_06790	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO44_06810	COG0864	Transcriptional regulator
OIO44_06820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO44_06825	COG1116	anion transmembrane transporter activity
OIO44_06945	COG0590	tRNA wobble adenosine to inosine editing
OIO44_06950	COG2807	transmembrane transport
OIO44_06965	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OIO44_06980	COG0789	Transcriptional regulator
OIO44_06990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO44_07010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO44_07020	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO44_07035	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_07040	COG0531	amino acid
OIO44_07045	COG1760	l-serine dehydratase
OIO44_07050	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_07050	COG2030	dehydratase
OIO44_07055	COG3396	Phenylacetate-CoA oxygenase
OIO44_07060	COG3460	Phenylacetate-CoA oxygenase
OIO44_07065	COG3396	Phenylacetate-CoA oxygenase
OIO44_07070	COG2151	metal-sulfur cluster biosynthetic enzyme
OIO44_07075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO44_07080	COG1024	Enoyl-CoA hydratase
OIO44_07085	COG1024	Enoyl-CoA hydratase
OIO44_07090	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO44_07095	COG0183	Belongs to the thiolase family
OIO44_07100	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OIO44_07105	COG3327	negative regulation of DNA-templated transcription, initiation
OIO44_07115	COG2050	protein possibly involved in aromatic compounds catabolism
OIO44_07150	COG0753	catalase activity
OIO44_07155	COG3038	cytochrome b561
OIO44_07175	COG2267	carboxylic ester hydrolase activity
OIO44_07180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO44_07185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO44_07190	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_07200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO44_07210	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_07215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO44_07220	COG0583	DNA-binding transcription factor activity
OIO44_07230	COG1414	Transcriptional regulator
OIO44_07235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO44_07245	COG1840	ABC-type Fe3 transport system, periplasmic component
OIO44_07250	COG3842	ATPase activity
OIO44_07265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OIO44_07270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO44_07275	COG2814	Major facilitator Superfamily
OIO44_07280	COG1960	acyl-CoA dehydrogenase activity
OIO44_07295	COG1024	Enoyl-CoA hydratase
OIO44_07305	COG2814	Major facilitator Superfamily
OIO44_07315	COG0183	Belongs to the thiolase family
OIO44_07320	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO44_07325	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_07330	COG1024	Enoyl-CoA hydratase
OIO44_07335	COG1960	acyl-CoA dehydrogenase activity
OIO44_07340	COG2814	Major facilitator Superfamily
OIO44_07345	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO44_07350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO44_07360	COG2814	Major facilitator Superfamily
OIO44_07370	COG1960	acyl-CoA dehydrogenase activity
OIO44_07385	COG0583	DNA-binding transcription factor activity
OIO44_07395	COG4770	biotin carboxylase activity
OIO44_07400	COG1024	Enoyl-CoA hydratase
OIO44_07405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO44_07410	COG1960	acyl-CoA dehydrogenase activity
OIO44_07415	COG1309	transcriptional regulator
OIO44_07420	COG0318	PFAM AMP-dependent synthetase and ligase
OIO44_07440	COG0583	DNA-binding transcription factor activity
OIO44_07490	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_07510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIO44_07530	COG2205	protein histidine kinase activity
OIO44_07530	COG0784	Response regulator, receiver
OIO44_07550	COG0765	amino acid transport
OIO44_07555	COG0765	amino acid transport
OIO44_07560	COG1126	abc transporter atp-binding protein
OIO44_07565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO44_07570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO44_07595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIO44_07600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO44_07605	COG1045	serine acetyltransferase
OIO44_07620	COG0583	DNA-binding transcription factor activity
OIO44_07625	COG0625	glutathione transferase activity
OIO44_07630	COG0625	glutathione transferase activity
OIO44_07635	COG0583	DNA-binding transcription factor activity
OIO44_07645	COG1346	cytolysis
OIO44_07665	COG2814	Major facilitator Superfamily
OIO44_07675	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OIO44_07680	COG3052	prosthetic group binding
OIO44_07700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OIO44_07720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO44_07730	COG1294	oxidase, subunit
OIO44_07735	COG1271	oxidase subunit
OIO44_07755	COG0477	Major facilitator Superfamily
OIO44_07765	COG4521	taurine ABC transporter
OIO44_07770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OIO44_07775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO44_07780	COG2175	clavaminate synthase activity
OIO44_07790	COG1953	Uracil, thiamine, allantoin
OIO44_07800	COG0583	DNA-binding transcription factor activity
OIO44_07810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIO44_07825	COG0640	Transcriptional regulator
OIO44_07830	COG0798	PFAM Bile acid sodium symporter
OIO44_07835	COG0583	DNA-binding transcription factor activity
OIO44_07850	COG3634	alkyl hydroperoxide reductase activity
OIO44_07890	COG0436	Aminotransferase
OIO44_07900	COG0386	Belongs to the glutathione peroxidase family
OIO44_07940	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO44_07965	COG0012	GTP binding
OIO44_07970	COG2011	ABC-type metal ion transport system permease component
OIO44_07975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO44_07985	COG1464	Belongs to the NlpA lipoprotein family
OIO44_08015	COG0765	amino acid transport
OIO44_08020	COG0765	amino acid transport
OIO44_08025	COG1126	abc transporter atp-binding protein
OIO44_08035	COG1522	sequence-specific DNA binding
OIO44_08050	COG1309	transcriptional regulator
OIO44_08070	COG0583	DNA-binding transcription factor activity
OIO44_08080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO44_08090	COG0697	spore germination
OIO44_08145	COG2135	peptidase activity
OIO44_08160	COG3300	MHYT domain
OIO44_08160	COG5001	Diguanylate cyclase
OIO44_08180	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIO44_08180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO44_08180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO44_08185	COG1105	Belongs to the carbohydrate kinase PfkB family
OIO44_08190	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO44_08190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIO44_08220	COG0024	Methionine aminopeptidase
OIO44_08225	COG0583	DNA-binding transcription factor activity
OIO44_08235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OIO44_08240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO44_08245	COG0516	GMP reductase activity
OIO44_08245	COG0517	IMP dehydrogenase activity
OIO44_08270	COG0552	protein localization to endoplasmic reticulum
OIO44_08280	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OIO44_08295	COG4890	Cyd operon protein YbgT
OIO44_08300	COG1294	oxidase, subunit
OIO44_08315	COG1585	Membrane protein implicated in regulation of membrane protease activity
OIO44_08325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIO44_08330	COG4774	siderophore transport
OIO44_08345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIO44_08350	COG0569	domain protein
OIO44_08355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO44_08385	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIO44_08390	COG0542	response to heat
OIO44_08415	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO44_08415	COG1902	pentaerythritol trinitrate reductase activity
OIO44_08460	COG2323	membrane
OIO44_08465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OIO44_08475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO44_08480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO44_08485	COG0183	Belongs to the thiolase family
OIO44_08490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIO44_08495	COG0596	Alpha beta hydrolase
OIO44_08500	COG2271	Major facilitator Superfamily
OIO44_08505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO44_08510	COG3485	protocatechuate 3,4-dioxygenase
OIO44_08515	COG3485	protocatechuate 3,4-dioxygenase
OIO44_08520	COG0710	3-dehydroquinate dehydratase activity
OIO44_08525	COG3420	alginic acid biosynthetic process
OIO44_08530	COG3659	wide pore channel activity
OIO44_08535	COG4993	Dehydrogenase
OIO44_08545	COG2391	methyltransferase activity
OIO44_08560	COG1414	Transcriptional regulator
OIO44_08565	COG0583	DNA-binding transcription factor activity
OIO44_08570	COG1960	acyl-CoA dehydrogenase activity
OIO44_08595	COG2814	Major facilitator Superfamily
OIO44_08605	COG0154	amidase activity
OIO44_08625	COG4638	Rieske (2fe-2S)
OIO44_08635	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_08645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO44_08655	COG3733	amine oxidase
OIO44_08665	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_08675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO44_08680	COG0183	Belongs to the thiolase family
OIO44_08685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO44_08690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO44_08700	COG4829	muconolactone delta-isomerase
OIO44_08705	COG4948	Mandelate Racemase Muconate Lactonizing
OIO44_08710	COG0583	DNA-binding transcription factor activity
OIO44_08720	COG2186	Transcriptional regulator
OIO44_08740	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_08760	COG1960	acyl-CoA dehydrogenase activity
OIO44_08765	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_08770	COG3829	transcription factor binding
OIO44_08780	COG3162	membrane
OIO44_08795	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_08810	COG0753	catalase activity
OIO44_08830	COG1846	Transcriptional regulator
OIO44_08835	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO44_08835	COG1902	pentaerythritol trinitrate reductase activity
OIO44_08845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OIO44_08875	COG1309	transcriptional regulator
OIO44_08885	COG1335	isochorismatase
OIO44_08895	COG0583	DNA-binding transcription factor activity
OIO44_08905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO44_08905	COG0475	glutathione-regulated potassium exporter activity
OIO44_08915	COG1473	amidohydrolase
OIO44_08925	COG2831	hemolysin activation secretion protein
OIO44_08930	COG3210	domain, Protein
OIO44_08960	COG2188	Transcriptional regulator
OIO44_08975	COG0583	DNA-binding transcription factor activity
OIO44_09005	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO44_09035	COG1566	PFAM secretion protein HlyD family protein
OIO44_09050	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_09055	COG0129	dihydroxy-acid dehydratase activity
OIO44_09065	COG0583	DNA-binding transcription factor activity
OIO44_09070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO44_09080	COG2084	Dehydrogenase
OIO44_09085	COG2207	Transcriptional regulator
OIO44_09100	COG1064	alcohol dehydrogenase
OIO44_09110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO44_09115	COG1120	ATPase activity
OIO44_09135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO44_09255	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OIO44_09305	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_09320	COG2207	Transcriptional regulator
OIO44_09330	COG2205	protein histidine kinase activity
OIO44_09335	COG0745	RESPONSE REGULATOR receiver
OIO44_09340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO44_09345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO44_09350	COG1538	Outer membrane efflux protein
OIO44_09360	COG2072	flavoprotein involved in K transport
OIO44_09380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO44_09400	COG3539	Fimbrial protein
OIO44_09430	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO44_09440	COG0753	catalase activity
OIO44_09455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO44_09515	COG3433	isochorismatase activity
OIO44_09515	COG1535	isochorismatase
OIO44_09520	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_09525	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OIO44_09530	COG4149	molybdate abc transporter
OIO44_09535	COG0725	ABC transporter, periplasmic molybdate-binding protein
OIO44_09545	COG4638	Rieske (2fe-2S)
OIO44_09550	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO44_09555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO44_09555	COG0543	2 iron, 2 sulfur cluster binding
OIO44_09580	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_09595	COG2207	Transcriptional regulator
OIO44_09605	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_09610	COG2610	gluconate transmembrane transporter activity
OIO44_09620	COG0583	DNA-binding transcription factor activity
OIO44_09630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO44_09635	COG2031	fatty acid transporter
OIO44_09640	COG0183	Belongs to the thiolase family
OIO44_09645	COG0583	DNA-binding transcription factor activity
OIO44_09650	COG0583	DNA-binding transcription factor activity
OIO44_09665	COG1027	Aspartate ammonia-lyase
OIO44_09675	COG0477	Major facilitator Superfamily
OIO44_09695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO44_09700	COG4521	taurine ABC transporter
OIO44_09715	COG2188	Transcriptional regulator
OIO44_09725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIO44_09730	COG1733	regulation of RNA biosynthetic process
OIO44_09735	COG2207	Transcriptional regulator
OIO44_09735	COG3708	Transcriptional regulator
OIO44_09750	COG0730	response to heat
OIO44_09765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO44_09765	COG3453	Protein conserved in bacteria
OIO44_09775	COG3781	membrane
OIO44_09780	COG1063	alcohol dehydrogenase
OIO44_09790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO44_09795	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO44_09800	COG0022	dehydrogenase e1 component
OIO44_09805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OIO44_09810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO44_09825	COG3706	GGDEF domain
OIO44_09840	COG0133	tryptophan synthase activity
OIO44_09850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO44_09885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIO44_09910	COG2226	methyltransferase
OIO44_09965	COG0842	Transport permease protein
OIO44_09970	COG0842	Transport permease protein
OIO44_09975	COG1131	(ABC) transporter
OIO44_09990	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO44_09995	COG4773	Receptor
OIO44_10015	COG0730	response to heat
OIO44_10020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO44_10040	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIO44_10055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO44_10095	COG4264	IucA IucC family
OIO44_10100	COG4264	IucA IucC family
OIO44_10120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIO44_10135	COG1960	acyl-CoA dehydrogenase activity
OIO44_10140	COG1960	acyl-CoA dehydrogenase activity
OIO44_10160	COG2207	Transcriptional regulator
OIO44_10165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO44_10170	COG0776	regulation of translation
OIO44_10195	COG0822	iron-sulfur transferase activity
OIO44_10200	COG0316	Belongs to the HesB IscA family
OIO44_10230	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO44_10250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO44_10255	COG0702	epimerase
OIO44_10290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIO44_10300	COG0339	signal peptide processing
OIO44_10350	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIO44_10355	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OIO44_10385	COG0776	regulation of translation
OIO44_10450	COG0084	hydrolase, TatD family'
OIO44_10470	COG1663	tetraacyldisaccharide 4'-kinase activity
OIO44_10475	COG1132	(ABC) transporter
OIO44_10485	COG0811	peptide transport
OIO44_10490	COG1475	DNA binding
OIO44_10495	COG1192	Involved in chromosome partitioning
OIO44_10505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIO44_10520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO44_10525	COG0191	fructose-bisphosphate aldolase activity
OIO44_10545	COG0424	maF-like protein
OIO44_10550	COG2850	peptidyl-arginine hydroxylation
OIO44_10560	COG0640	Transcriptional regulator
OIO44_10570	COG3619	membrane
OIO44_10575	COG3122	Protein conserved in bacteria
OIO44_10580	COG1132	(ABC) transporter
OIO44_10600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIO44_10605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO44_10615	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO44_10615	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO44_10615	COG0506	proline dehydrogenase activity
OIO44_10620	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIO44_10635	COG3698	Phosphodiester glycosidase
OIO44_10645	COG2353	YceI-like domain
OIO44_10655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIO44_10705	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIO44_10705	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIO44_10730	COG3539	Fimbrial protein
OIO44_10735	COG3121	Chaperone
OIO44_10745	COG1011	Hydrolase
OIO44_10750	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OIO44_10760	COG2137	regulation of response to DNA damage stimulus
OIO44_10775	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO44_10810	COG0575	Belongs to the CDS family
OIO44_10815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIO44_10835	COG3852	Histidine kinase
OIO44_10840	COG2204	response regulator
OIO44_10895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO44_10900	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OIO44_10920	COG0697	spore germination
OIO44_10925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO44_10935	COG0303	'Molybdopterin
OIO44_10940	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIO44_10940	COG0315	cyclic pyranopterin monophosphate synthase activity
OIO44_10955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OIO44_10960	COG0243	molybdopterin cofactor binding
OIO44_10970	COG0243	molybdopterin cofactor binding
OIO44_10975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO44_10980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO44_10980	COG2146	nitrite reductase [NAD(P)H] activity
OIO44_10990	COG0745	RESPONSE REGULATOR receiver
OIO44_10995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO44_10995	COG1116	anion transmembrane transporter activity
OIO44_11015	COG0511	ligase activity, forming carbon-carbon bonds
OIO44_11030	COG2814	Major facilitator Superfamily
OIO44_11235	COG5410	chromosome segregation
OIO44_11400	COG0069	glutamate synthase activity
OIO44_11420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIO44_11430	COG1454	alcohol dehydrogenase
OIO44_11435	COG0824	Thioesterase
OIO44_11445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIO44_11460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO44_11465	COG2030	dehydratase
OIO44_11475	COG0183	Belongs to the thiolase family
OIO44_11485	COG0583	DNA-binding transcription factor activity
OIO44_11490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIO44_11500	COG1522	sequence-specific DNA binding
OIO44_11505	COG3135	benzoate transporter
OIO44_11515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIO44_11540	COG0589	response to stress
OIO44_11545	COG0488	(ABC) transporter
OIO44_11565	COG4773	Receptor
OIO44_11595	COG0668	transmembrane transport
OIO44_11605	COG1309	transcriptional regulator
OIO44_11625	COG1605	Chorismate mutase
OIO44_11635	COG4221	oxidoreductase activity
OIO44_11645	COG0308	aminopeptidase N
OIO44_11665	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OIO44_11675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO44_11680	COG1454	alcohol dehydrogenase
OIO44_11700	COG0531	amino acid
OIO44_11705	COG4303	Ethanolamine ammonia lyase large subunit
OIO44_11710	COG4302	ethanolamine ammonia-lyase activity
OIO44_11715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO44_11715	COG0519	Catalyzes the synthesis of GMP from XMP
OIO44_11720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO44_11730	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO44_11745	COG0697	spore germination
OIO44_11750	COG1923	regulation of RNA biosynthetic process
OIO44_11760	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIO44_11765	COG0802	atpase or kinase
OIO44_11785	COG1187	pseudouridine synthase activity
OIO44_11800	COG0583	DNA-binding transcription factor activity
OIO44_11815	COG2814	Major facilitator Superfamily
OIO44_11820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO44_11845	COG0729	surface antigen
OIO44_11865	COG0174	glutamine synthetase
OIO44_11870	COG0745	RESPONSE REGULATOR receiver
OIO44_11875	COG2205	protein histidine kinase activity
OIO44_11885	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIO44_11890	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIO44_11915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO44_11920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO44_11925	COG1960	acyl-CoA dehydrogenase activity
OIO44_11940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO44_11945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO44_11965	COG0583	DNA-binding transcription factor activity
OIO44_11980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO44_11990	COG3658	cytochrome
OIO44_11995	COG1215	transferase activity, transferring glycosyl groups
OIO44_12000	COG1649	PFAM Uncharacterised BCR, COG1649
OIO44_12000	COG0726	polysaccharide deacetylase
OIO44_12025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIO44_12030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIO44_12040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OIO44_12065	COG0305	Participates in initiation and elongation during chromosome replication
OIO44_12070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIO44_12080	COG1305	Transglutaminase-like
OIO44_12090	COG2308	Evidence 4 Homologs of previously reported genes of
OIO44_12120	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OIO44_12125	COG0138	bifunctional purine biosynthesis protein purh
OIO44_12130	COG0151	Belongs to the GarS family
OIO44_12135	COG1464	Belongs to the NlpA lipoprotein family
OIO44_12145	COG2011	ABC-type metal ion transport system permease component
OIO44_12150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO44_12160	COG1301	dicarboxylic acid transport
OIO44_12190	COG1794	racemase activity, acting on amino acids and derivatives
OIO44_12200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIO44_12200	COG3008	intermembrane lipid transfer
OIO44_12205	COG2995	paraquat-inducible protein a
OIO44_12215	COG2985	domain, Protein
OIO44_12245	COG0477	Major facilitator Superfamily
OIO44_12295	COG2186	Transcriptional regulator
OIO44_12305	COG0786	glutamate:sodium symporter activity
OIO44_12310	COG3243	poly(R)-hydroxyalkanoic acid synthase
OIO44_12335	COG3111	PFAM Bacterial OB fold (BOF) protein
OIO44_12435	COG1610	YqeY-like protein
OIO44_12440	COG4783	chaperone-mediated protein folding
OIO44_12465	COG1286	toxin biosynthetic process
OIO44_12495	COG0778	Nitroreductase
OIO44_12505	COG0513	Belongs to the DEAD box helicase family
OIO44_12530	COG2363	Small membrane protein
OIO44_12560	COG1234	tRNA 3'-trailer cleavage
OIO44_12565	COG2195	Cleaves the N-terminal amino acid of tripeptides
OIO44_12575	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIO44_12585	COG2819	hydrolase of the alpha beta superfamily
OIO44_12590	COG1960	acyl-CoA dehydrogenase activity
OIO44_12595	COG1301	dicarboxylic acid transport
OIO44_12600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OIO44_12605	COG3139	Protein of unknown function (DUF1315)
OIO44_12610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIO44_12615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIO44_12625	COG0494	nUDIX hydrolase
OIO44_12635	COG0642	Histidine kinase
OIO44_12650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OIO44_12660	COG1720	tRNA m6t6A37 methyltransferase activity
OIO44_12675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO44_12680	COG0826	peptidase U32
OIO44_12685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO44_12695	COG4598	ABC transporter
OIO44_12700	COG4160	amino acid transport
OIO44_12705	COG4215	(ABC) transporter
OIO44_12730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO44_12775	COG1131	(ABC) transporter
OIO44_12780	COG0842	Transport permease protein
OIO44_12795	COG0772	Belongs to the SEDS family
OIO44_12800	COG2951	lytic endotransglycosylase activity
OIO44_12825	COG2207	Transcriptional regulator
OIO44_12840	COG0052	Belongs to the universal ribosomal protein uS2 family
OIO44_12845	COG0024	Methionine aminopeptidase
OIO44_12855	COG2223	nitrite transmembrane transporter activity
OIO44_12865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO44_12870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO44_12875	COG1960	acyl-CoA dehydrogenase activity
OIO44_12890	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIO44_12895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIO44_12900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO44_12920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO44_12925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIO44_12930	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIO44_12965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OIO44_12975	COG0174	glutamine synthetase
OIO44_12990	COG0582	viral genome integration into host DNA
OIO44_13195	COG5410	chromosome segregation
OIO44_13355	COG0512	Glutamine amidotransferase of anthranilate synthase
OIO44_13360	COG0308	aminopeptidase N
OIO44_13390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIO44_13400	COG0302	gtp cyclohydrolase
OIO44_13420	COG3739	integral membrane protein
OIO44_13435	COG1169	isochorismate synthase
OIO44_13445	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OIO44_13450	COG1132	(ABC) transporter
OIO44_13455	COG1132	(ABC) transporter
OIO44_13470	COG3433	isochorismatase activity
OIO44_13470	COG1535	isochorismatase
OIO44_13475	COG1021	2,3-dihydroxybenzoate-AMP ligase
OIO44_13480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO44_13490	COG4774	siderophore transport
OIO44_13495	COG4607	ABC-type enterochelin transport system periplasmic component
OIO44_13500	COG4604	ABC transporter, ATP-binding protein
OIO44_13505	COG4605	iron ion homeostasis
OIO44_13510	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO44_13520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO44_13535	COG2964	Protein conserved in bacteria
OIO44_13545	COG1741	Belongs to the pirin family
OIO44_13565	COG1309	transcriptional regulator
OIO44_13575	COG4948	Mandelate Racemase Muconate Lactonizing
OIO44_13580	COG2814	Major facilitator Superfamily
OIO44_13615	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OIO44_13615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO44_13620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO44_13630	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_13640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO44_13645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO44_13650	COG0583	DNA-binding transcription factor activity
OIO44_13655	COG1113	amino acid transport
OIO44_13675	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OIO44_13675	COG2508	Transcriptional regulator
OIO44_13710	COG2879	small protein
OIO44_13715	COG1966	Carbon starvation protein
OIO44_13760	COG1067	ATP-dependent peptidase activity
OIO44_13765	COG0583	DNA-binding transcription factor activity
OIO44_13790	COG1686	Belongs to the peptidase S11 family
OIO44_13795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OIO44_13830	COG0616	signal peptide processing
OIO44_13835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIO44_13845	COG0573	inorganic phosphate transmembrane transporter activity
OIO44_13850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIO44_13855	COG1113	amino acid transport
OIO44_13860	COG3961	Belongs to the TPP enzyme family
OIO44_13865	COG1522	sequence-specific DNA binding
OIO44_13875	COG0076	glutamate decarboxylase activity
OIO44_13880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO44_13890	COG1309	transcriptional regulator
OIO44_13905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO44_13940	COG0352	thiamine-phosphate diphosphorylase activity
OIO44_13965	COG0612	Peptidase, M16
OIO44_13975	COG1823	symporter activity
OIO44_13980	COG0583	DNA-binding transcription factor activity
OIO44_13985	COG0477	Major facilitator Superfamily
OIO44_14010	COG1187	pseudouridine synthase activity
OIO44_14030	COG1252	NADH dehydrogenase
OIO44_14040	COG0415	Belongs to the DNA photolyase family
OIO44_14055	COG1215	transferase activity, transferring glycosyl groups
OIO44_14085	COG2070	2-Nitropropane dioxygenase
OIO44_14275	COG5410	chromosome segregation
OIO44_14475	COG0556	nucleotide-excision repair
OIO44_14495	COG0436	Aminotransferase
OIO44_14525	COG4221	oxidoreductase activity
OIO44_14535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OIO44_14540	COG1381	Involved in DNA repair and RecF pathway recombination
OIO44_14550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIO44_14565	COG0681	Belongs to the peptidase S26 family
OIO44_14580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO44_14600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIO44_14605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIO44_14610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OIO44_14620	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIO44_14625	COG4208	sulfate ABC transporter
OIO44_14630	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OIO44_14635	COG0583	DNA-binding transcription factor activity
OIO44_14640	COG4625	pathogenesis
OIO44_14655	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OIO44_14670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OIO44_14680	COG1051	belongs to the nudix hydrolase family
OIO44_14680	COG1056	cytidyltransferase-related domain
OIO44_14685	COG1024	Enoyl-CoA hydratase
OIO44_14700	COG2814	Major facilitator Superfamily
OIO44_14705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIO44_14705	COG0047	phosphoribosylformylglycinamidine synthase activity
OIO44_14725	COG1473	amidohydrolase
OIO44_14730	COG0824	Thioesterase
OIO44_14750	COG0823	Involved in the tonB-independent uptake of proteins
OIO44_14770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO44_14805	COG0628	permease
OIO44_14815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIO44_14820	COG0596	Alpha beta hydrolase
OIO44_14825	COG0616	signal peptide processing
OIO44_14825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIO44_14835	COG0658	competence protein
OIO44_14835	COG2333	competence protein COMEC
OIO44_14840	COG1136	(ABC) transporter
OIO44_14845	COG4591	ABC-type transport system involved in lipoprotein release permease component
OIO44_14880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO44_14900	COG0463	Glycosyl transferase, family 2
OIO44_14930	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO44_14935	COG1280	lysine exporter protein (LysE YggA)
OIO44_14945	COG0019	diaminopimelate decarboxylase activity
OIO44_14955	COG1113	amino acid transport
OIO44_14970	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OIO44_14980	COG3339	Conserved Protein
OIO44_14985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIO44_14990	COG0243	molybdopterin cofactor binding
OIO44_14995	COG1929	Belongs to the glycerate kinase type-1 family
OIO44_15010	COG0778	Nitroreductase
OIO44_15040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO44_15055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIO44_15075	COG0741	lytic transglycosylase activity
OIO44_15095	COG0584	glycerophosphoryl diester phosphodiesterase
OIO44_15100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO44_15125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO44_15130	COG1597	lipid kinase activity
OIO44_15145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIO44_15150	COG0477	Major facilitator Superfamily
OIO44_15200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIO44_15205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO44_15230	COG0505	Belongs to the CarA family
OIO44_15250	COG0589	response to stress
OIO44_15265	COG2843	Capsule synthesis protein
OIO44_15285	COG2321	neutral zinc metallopeptidase
OIO44_15290	COG2354	Protein conserved in bacteria
OIO44_15310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO44_15335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIO44_15340	COG1053	succinate dehydrogenase
OIO44_15345	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OIO44_15350	COG2009	succinate dehydrogenase
OIO44_15390	COG2921	Belongs to the UPF0250 family
OIO44_15395	COG0321	lipoyl(octanoyl) transferase activity
OIO44_15410	COG0531	amino acid
OIO44_15420	COG1733	regulation of RNA biosynthetic process
OIO44_15425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIO44_15430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIO44_15430	COG1648	precorrin-2 dehydrogenase activity
OIO44_15445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OIO44_15475	COG0671	phosphoesterase, PA-phosphatase related
OIO44_15480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO44_15490	COG1538	Outer membrane efflux protein
OIO44_15495	COG0393	Putative heavy-metal-binding
OIO44_15500	COG0393	Putative heavy-metal-binding
OIO44_15510	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_15520	COG0525	valine-tRNA ligase activity
OIO44_15540	COG0583	DNA-binding transcription factor activity
OIO44_15545	COG0004	ammonium transporteR
OIO44_15555	COG0642	Histidine kinase
OIO44_15560	COG0745	RESPONSE REGULATOR receiver
OIO44_15565	COG2194	sulfuric ester hydrolase activity
OIO44_15590	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO44_15605	COG2315	Protein conserved in bacteria
OIO44_15610	COG0142	geranyltranstransferase activity
OIO44_15615	COG2828	Protein conserved in bacteria
OIO44_15620	COG1113	amino acid transport
OIO44_15640	COG2207	Transcriptional regulator
OIO44_15665	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO44_15675	COG0560	Phosphoserine phosphatase
OIO44_15685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO44_15695	COG1530	ribonuclease E activity
OIO44_15700	COG0424	maF-like protein
OIO44_15705	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OIO44_15710	COG1792	Involved in formation and maintenance of cell shape
OIO44_15715	COG1077	Cell shape determining protein MreB Mrl
OIO44_15720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO44_15730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO44_15760	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OIO44_15765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO44_15770	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO44_15775	COG1115	amino acid carrier protein
OIO44_15795	COG2814	Major facilitator Superfamily
OIO44_15800	COG1289	transmembrane transporter activity
OIO44_15810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OIO44_15850	COG1376	ErfK ybiS ycfS ynhG family protein
OIO44_15855	COG2832	Protein of unknown function (DUF454)
OIO44_15865	COG5510	response to toxic substance
OIO44_15885	COG0840	transmembrane signaling receptor activity
OIO44_15925	COG3422	double-strand break repair
OIO44_15930	COG2824	Alkylphosphonate utilization operon protein PhnA
OIO44_15935	COG3189	MarR family transcriptional regulator
OIO44_15945	COG0354	folic acid binding
OIO44_15950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO44_15960	COG0679	Auxin Efflux Carrier
OIO44_15965	COG1902	pentaerythritol trinitrate reductase activity
OIO44_15970	COG4772	TonB-dependent receptor
OIO44_15975	COG2094	Belongs to the DNA glycosylase MPG family
OIO44_16000	COG1217	gtp-binding protein TYPA
OIO44_16005	COG2233	PERMEase
OIO44_16015	COG0833	amino acid
OIO44_16020	COG1690	Belongs to the RtcB family
OIO44_16030	COG2885	chlorophyll binding
OIO44_16030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OIO44_16040	COG0183	Belongs to the thiolase family
OIO44_16060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO44_16080	COG2207	Transcriptional regulator
OIO44_16085	COG0183	Belongs to the thiolase family
OIO44_16115	COG1272	protein, Hemolysin III
OIO44_16120	COG0477	Major facilitator Superfamily
OIO44_16135	COG0450	alkyl hydroperoxide reductase
OIO44_16155	COG0285	dihydrofolate synthase activity
OIO44_16205	COG2096	Adenosyltransferase
OIO44_16225	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OIO44_16230	COG0745	RESPONSE REGULATOR receiver
OIO44_16235	COG2205	protein histidine kinase activity
OIO44_16245	COG1960	acyl-CoA dehydrogenase activity
OIO44_16250	COG1960	acyl-CoA dehydrogenase activity
OIO44_16255	COG0583	DNA-binding transcription factor activity
OIO44_16260	COG0625	glutathione transferase activity
OIO44_16325	COG0438	transferase activity, transferring glycosyl groups
OIO44_16330	COG0463	Glycosyl transferase, family 2
OIO44_16335	COG0726	polysaccharide deacetylase
OIO44_16355	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIO44_16360	COG2205	protein histidine kinase activity
OIO44_16410	COG1862	Preprotein translocase
OIO44_16420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIO44_16425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIO44_16435	COG3781	membrane
OIO44_16440	COG0613	PHP domain protein
OIO44_16450	COG2350	Protein conserved in bacteria
OIO44_16480	COG1607	acyl-coa hydrolase
OIO44_16540	COG2199	diguanylate cyclase activity
OIO44_16550	COG1408	metallophosphoesterase
OIO44_16555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO44_16565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIO44_16585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIO44_16590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIO44_16605	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIO44_16615	COG2969	positive regulation of protein catabolic process
OIO44_16635	COG1960	acyl-CoA dehydrogenase activity
OIO44_16640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO44_16655	COG1309	transcriptional regulator
OIO44_16660	COG1960	acyl-CoA dehydrogenase activity
OIO44_16705	COG1183	phosphatidylcholine synthase activity
OIO44_16710	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OIO44_16740	COG0739	heme binding
OIO44_16740	COG0741	lytic transglycosylase activity
OIO44_16740	COG1196	nuclear chromosome segregation
OIO44_16750	COG1702	phosphate starvation-inducible protein PhoH
OIO44_16785	COG1295	ribonuclease BN
OIO44_16790	COG0697	spore germination
OIO44_16795	COG2169	Transcriptional regulator
OIO44_16800	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO44_16845	COG0557	exoribonuclease II activity
OIO44_16850	COG0339	signal peptide processing
OIO44_16855	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OIO44_16885	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OIO44_16890	COG1960	acyl-CoA dehydrogenase activity
OIO44_17045	COG0626	cystathionine gamma-synthase activity
OIO44_17050	COG0433	COG0433 Predicted ATPase
OIO44_17055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO44_17055	COG1017	nitric oxide dioxygenase activity
OIO44_17060	COG1959	2 iron, 2 sulfur cluster binding
OIO44_17075	COG1301	dicarboxylic acid transport
OIO44_17080	COG1946	Acyl-CoA thioesterase
OIO44_17100	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIO44_17105	COG1040	competence protein
OIO44_17110	COG0494	nUDIX hydrolase
OIO44_17120	COG0598	Magnesium transport protein CorA
OIO44_17130	COG2854	intermembrane phospholipid transfer
OIO44_17140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIO44_17145	COG1127	ABC transporter
OIO44_17155	COG0513	Belongs to the DEAD box helicase family
OIO44_17175	COG0408	coproporphyrinogen oxidase activity
OIO44_17190	COG1960	acyl-CoA dehydrogenase activity
OIO44_17200	COG1983	PspC domain protein
OIO44_17205	COG0517	IMP dehydrogenase activity
OIO44_17250	COG0583	DNA-binding transcription factor activity
OIO44_17290	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_17300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO44_17305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO44_17310	COG0833	amino acid
OIO44_17340	COG1192	Involved in chromosome partitioning
OIO44_17345	COG0628	permease
OIO44_17355	COG1289	transmembrane transporter activity
OIO44_17370	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO44_17375	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OIO44_17385	COG0277	FAD linked oxidase domain protein
OIO44_17390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIO44_17415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIO44_17420	COG5380	lipid catabolic process
OIO44_17440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIO44_17490	COG0194	GDP metabolic process
OIO44_17505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO44_17525	COG3307	-O-antigen
OIO44_17530	COG4969	Belongs to the N-Me-Phe pilin family
OIO44_17540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OIO44_17545	COG1704	LemA family
OIO44_17555	COG0493	'glutamate synthase
OIO44_17560	COG0069	glutamate synthase activity
OIO44_17560	COG0070	glutamate synthase
OIO44_17560	COG0067	glutamate synthase
OIO44_17610	COG2226	methyltransferase
OIO44_17625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIO44_17630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIO44_17675	COG0833	amino acid
OIO44_17760	COG0488	(ABC) transporter
OIO44_17765	COG2873	o-acetylhomoserine
OIO44_17770	COG4221	oxidoreductase activity
OIO44_17775	COG0659	secondary active sulfate transmembrane transporter activity
OIO44_17800	COG0427	acetyl-CoA hydrolase
OIO44_17830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIO44_17870	COG2329	Antibiotic biosynthesis monooxygenase
OIO44_17885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OIO44_17950	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO44_17955	COG1733	regulation of RNA biosynthetic process
OIO44_17990	COG0667	Aldo Keto reductase
OIO44_18010	COG0583	DNA-binding transcription factor activity
OIO44_18015	COG2814	Major facilitator Superfamily
OIO44_18045	COG1335	isochorismatase
OIO44_18055	COG1012	belongs to the aldehyde dehydrogenase family
OIO44_18060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO44_18070	COG1113	amino acid transport
OIO44_18080	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO44_18095	COG2814	Major facilitator Superfamily
OIO44_18105	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO44_18105	COG0351	phosphomethylpyrimidine kinase
OIO44_18105	COG0352	thiamine-phosphate diphosphorylase activity
OIO44_18125	COG1309	transcriptional regulator
OIO44_18130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIO44_18150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO44_18160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO44_18165	COG3162	membrane
OIO44_18170	COG2205	protein histidine kinase activity
OIO44_18170	COG2198	Histidine kinase
OIO44_18170	COG0784	Response regulator, receiver
OIO44_18195	COG3328	transposase activity
OIO44_18200	COG1522	sequence-specific DNA binding
OIO44_18205	COG1335	isochorismatase
OIO44_18210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO44_18220	COG0668	transmembrane transport
OIO44_18225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO44_18230	COG1519	Transferase
OIO44_18235	COG1902	pentaerythritol trinitrate reductase activity
OIO44_18255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OIO44_18280	COG0426	domain, Protein
OIO44_18280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO44_18285	COG4774	siderophore transport
OIO44_18290	COG2119	membrane
OIO44_18300	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO44_18310	COG4942	peptidase
OIO44_18325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIO44_18335	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIO44_18355	COG0189	ligase activity
OIO44_18400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO44_18445	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO44_18475	COG0659	secondary active sulfate transmembrane transporter activity
OIO44_18480	COG0589	response to stress
OIO44_18515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO44_18525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO44_18545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIO44_18560	COG0318	PFAM AMP-dependent synthetase and ligase
OIO44_18570	COG0477	Major facilitator Superfamily
OIO44_18575	COG2860	membrane
OIO44_18585	COG1253	flavin adenine dinucleotide binding
OIO44_18605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO44_18645	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIO44_18655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIO44_18725	COG0758	DNA mediated transformation
OIO44_18735	COG0697	spore germination
OIO44_18740	COG1309	transcriptional regulator
OIO44_18755	COG0386	Belongs to the glutathione peroxidase family
OIO44_18820	COG1121	(ABC) transporter
OIO44_18825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIO44_18830	COG1280	lysine exporter protein (LysE YggA)
OIO44_18835	COG2837	iron assimilation
OIO44_18845	COG0281	malic enzyme
OIO44_18890	COG0519	Catalyzes the synthesis of GMP from XMP
OIO44_18890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO44_18895	COG4399	Belongs to the UPF0754 family
OIO44_18900	COG2259	Doxx family
OIO44_18905	COG0586	Pfam SNARE associated Golgi protein
OIO44_18920	COG1192	Involved in chromosome partitioning
OIO44_18930	COG0271	Belongs to the BolA IbaG family
OIO44_18950	COG2267	carboxylic ester hydrolase activity
OIO44_18970	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OIO44_18970	COG3321	synthase
OIO44_18970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIO44_18970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO44_18975	COG1960	acyl-CoA dehydrogenase activity
OIO44_18985	COG2197	response regulator
OIO44_18995	COG3916	Acyl-homoserine-lactone synthase
OIO44_19000	COG0477	Major facilitator Superfamily
OIO44_19005	COG1024	Enoyl-CoA hydratase
OIO44_19010	COG1024	Enoyl-CoA hydratase
OIO44_19015	COG1960	acyl-CoA dehydrogenase activity
OIO44_19020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO44_19040	COG1113	amino acid transport
OIO44_19045	COG1113	amino acid transport
OIO44_19050	COG0251	oxidation-reduction process
OIO44_19090	COG0564	pseudouridine synthase activity
OIO44_19150	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIO44_19165	COG1802	Transcriptional regulator
OIO44_19175	COG1448	Aminotransferase
OIO44_19180	COG0277	FAD linked oxidase domain protein
OIO44_19190	COG2186	Transcriptional regulator
OIO44_19200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO44_19205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO44_19220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIO44_19230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OIO44_19240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OIO44_19245	COG0438	transferase activity, transferring glycosyl groups
OIO44_19265	COG1216	Glycosyl transferase, family 2
OIO44_19270	COG5039	Polysaccharide pyruvyl transferase
OIO44_19280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OIO44_19285	COG1596	polysaccharide export
OIO44_19310	COG0728	peptidoglycan biosynthetic process
OIO44_19315	COG3023	N-Acetylmuramoyl-L-alanine amidase
OIO44_19375	COG0546	phosphoglycolate phosphatase activity
OIO44_19380	COG1028	Short-chain dehydrogenase reductase Sdr
OIO44_19400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO44_19405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO44_19410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO44_19415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO44_19420	COG1116	anion transmembrane transporter activity
OIO44_19425	COG1309	transcriptional regulator
OIO44_19430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO44_19440	COG0196	riboflavin kinase activity
OIO44_19445	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIO44_19455	COG1047	Peptidyl-prolyl cis-trans
OIO44_19495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIO44_19500	COG0657	acetylesterase activity
OIO44_19520	COG0583	DNA-binding transcription factor activity
OIO44_19550	COG2951	lytic endotransglycosylase activity
OIO44_19555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIO44_19570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIO44_19580	COG0671	phosphoesterase, PA-phosphatase related
OIO44_19585	COG0861	Integral membrane protein TerC family
OIO44_19595	COG0754	glutathionylspermidine amidase activity
OIO44_19605	COG0402	S-adenosylhomocysteine deaminase activity
OIO44_19620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO44_19625	COG1230	cation diffusion facilitator family transporter
OIO44_19640	COG0706	membrane insertase activity
OIO44_19710	COG1525	nuclease
OIO44_19770	COG1475	DNA binding
OIO44_19785	COG3853	Toxic anion resistance protein (TelA)
OIO44_19870	COG0484	heat shock protein binding
OIO44_19955	COG0741	lytic transglycosylase activity
OIO44_19990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO44_20120	COG0627	Serine hydrolase involved in the detoxification of formaldehyde