locus-tag	class	description
OIO65_00010	COG0592	DNA-directed DNA polymerase activity
OIO65_00020	COG0187	DNA topoisomerase II activity
OIO65_00030	COG0586	Pfam SNARE associated Golgi protein
OIO65_00035	COG0488	(ABC) transporter
OIO65_00060	COG0596	Alpha beta hydrolase
OIO65_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OIO65_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO65_00110	COG0733	neurotransmitter:sodium symporter activity
OIO65_00150	COG2233	PERMEase
OIO65_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO65_00200	COG2814	Major facilitator Superfamily
OIO65_00205	COG0656	L-ascorbic acid biosynthetic process
OIO65_00210	COG0583	DNA-binding transcription factor activity
OIO65_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO65_00230	COG1064	alcohol dehydrogenase
OIO65_00235	COG2818	Glycosylase
OIO65_00250	COG1194	a g-specific adenine glycosylase
OIO65_00270	COG2983	Belongs to the UPF0260 family
OIO65_00280	COG3121	Chaperone
OIO65_00285	COG3188	usher protein
OIO65_00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OIO65_00305	COG2116	formate transmembrane transporter activity
OIO65_00325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO65_00330	COG1335	isochorismatase
OIO65_00335	COG0385	Bile acid
OIO65_00340	COG0534	Mate efflux family protein
OIO65_00345	COG1683	Conserved Protein
OIO65_00365	COG0625	glutathione transferase activity
OIO65_00375	COG1113	amino acid transport
OIO65_00385	COG0523	cobalamin synthesis protein
OIO65_00395	COG2188	Transcriptional regulator
OIO65_00425	COG0010	Belongs to the arginase family
OIO65_00445	COG1280	lysine exporter protein (LysE YggA)
OIO65_00470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIO65_00480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OIO65_00485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OIO65_00570	COG0534	Mate efflux family protein
OIO65_00575	COG0436	Aminotransferase
OIO65_00580	COG2733	membrane
OIO65_00595	COG2918	glutathione biosynthetic process
OIO65_00620	COG3150	esterase
OIO65_00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OIO65_00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO65_00650	COG2233	PERMEase
OIO65_00655	COG2351	hydroxyisourate hydrolase activity
OIO65_00690	COG3706	GGDEF domain
OIO65_00705	COG1393	Belongs to the ArsC family
OIO65_00710	COG0708	Exodeoxyribonuclease III
OIO65_00730	COG0189	ligase activity
OIO65_00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIO65_00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIO65_00775	COG4942	peptidase
OIO65_00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO65_00795	COG2119	membrane
OIO65_00800	COG4774	siderophore transport
OIO65_00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO65_00805	COG0426	domain, Protein
OIO65_00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OIO65_00855	COG1902	pentaerythritol trinitrate reductase activity
OIO65_00860	COG1519	Transferase
OIO65_00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO65_00870	COG0668	transmembrane transport
OIO65_00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO65_00885	COG1335	isochorismatase
OIO65_00890	COG1522	sequence-specific DNA binding
OIO65_00915	COG2198	Histidine kinase
OIO65_00915	COG2205	protein histidine kinase activity
OIO65_00915	COG0784	Response regulator, receiver
OIO65_00920	COG3162	membrane
OIO65_00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO65_00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO65_00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIO65_00960	COG1309	transcriptional regulator
OIO65_00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO65_00980	COG0352	thiamine-phosphate diphosphorylase activity
OIO65_00980	COG0351	phosphomethylpyrimidine kinase
OIO65_00990	COG2814	Major facilitator Superfamily
OIO65_01030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO65_01040	COG1113	amino acid transport
OIO65_01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO65_01055	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_01065	COG1335	isochorismatase
OIO65_01100	COG2814	Major facilitator Superfamily
OIO65_01105	COG0583	DNA-binding transcription factor activity
OIO65_01120	COG1309	transcriptional regulator
OIO65_01140	COG0667	Aldo Keto reductase
OIO65_01175	COG1733	regulation of RNA biosynthetic process
OIO65_01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO65_01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OIO65_01260	COG2329	Antibiotic biosynthesis monooxygenase
OIO65_01275	COG1132	(ABC) transporter
OIO65_01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIO65_01325	COG0427	acetyl-CoA hydrolase
OIO65_01350	COG0659	secondary active sulfate transmembrane transporter activity
OIO65_01355	COG4221	oxidoreductase activity
OIO65_01360	COG2873	o-acetylhomoserine
OIO65_01365	COG0488	(ABC) transporter
OIO65_01430	COG0833	amino acid
OIO65_01475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIO65_01480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIO65_01495	COG2226	methyltransferase
OIO65_01545	COG0070	glutamate synthase
OIO65_01545	COG0069	glutamate synthase activity
OIO65_01545	COG0067	glutamate synthase
OIO65_01550	COG0493	'glutamate synthase
OIO65_01560	COG1704	LemA family
OIO65_01565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OIO65_01580	COG3307	-O-antigen
OIO65_01600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO65_01615	COG0194	GDP metabolic process
OIO65_01670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIO65_01690	COG5380	lipid catabolic process
OIO65_01695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIO65_01720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIO65_01725	COG0277	FAD linked oxidase domain protein
OIO65_01735	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OIO65_01740	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO65_01755	COG1289	transmembrane transporter activity
OIO65_01765	COG0628	permease
OIO65_01770	COG1192	Involved in chromosome partitioning
OIO65_01800	COG0833	amino acid
OIO65_01805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO65_01810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO65_01820	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_01860	COG0583	DNA-binding transcription factor activity
OIO65_01885	COG0752	glycyl-tRNA synthetase alpha subunit
OIO65_01910	COG0517	IMP dehydrogenase activity
OIO65_01915	COG1983	PspC domain protein
OIO65_01925	COG1960	acyl-CoA dehydrogenase activity
OIO65_01940	COG0408	coproporphyrinogen oxidase activity
OIO65_01960	COG0513	Belongs to the DEAD box helicase family
OIO65_01970	COG1127	ABC transporter
OIO65_01975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIO65_01985	COG2854	intermembrane phospholipid transfer
OIO65_01995	COG0598	Magnesium transport protein CorA
OIO65_02005	COG0494	nUDIX hydrolase
OIO65_02010	COG1040	competence protein
OIO65_02015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIO65_02035	COG1946	Acyl-CoA thioesterase
OIO65_02040	COG1301	dicarboxylic acid transport
OIO65_02055	COG1959	2 iron, 2 sulfur cluster binding
OIO65_02060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO65_02060	COG1017	nitric oxide dioxygenase activity
OIO65_02225	COG1960	acyl-CoA dehydrogenase activity
OIO65_02230	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OIO65_02260	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OIO65_02265	COG0339	signal peptide processing
OIO65_02270	COG0557	exoribonuclease II activity
OIO65_02315	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO65_02320	COG2169	Transcriptional regulator
OIO65_02325	COG0697	spore germination
OIO65_02330	COG1295	ribonuclease BN
OIO65_02365	COG1702	phosphate starvation-inducible protein PhoH
OIO65_02375	COG0739	heme binding
OIO65_02375	COG0741	lytic transglycosylase activity
OIO65_02375	COG1196	nuclear chromosome segregation
OIO65_02405	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OIO65_02410	COG1183	phosphatidylcholine synthase activity
OIO65_02455	COG1960	acyl-CoA dehydrogenase activity
OIO65_02460	COG1309	transcriptional regulator
OIO65_02475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO65_02480	COG1960	acyl-CoA dehydrogenase activity
OIO65_02500	COG2969	positive regulation of protein catabolic process
OIO65_02510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIO65_02520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OIO65_02525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIO65_02530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIO65_02550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIO65_02560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO65_02565	COG1408	metallophosphoesterase
OIO65_02575	COG2199	diguanylate cyclase activity
OIO65_02635	COG1607	acyl-coa hydrolase
OIO65_02665	COG2350	Protein conserved in bacteria
OIO65_02675	COG0613	PHP domain protein
OIO65_02680	COG3781	membrane
OIO65_02690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIO65_02695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIO65_02705	COG1862	Preprotein translocase
OIO65_02735	COG2205	protein histidine kinase activity
OIO65_02740	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIO65_02760	COG0726	polysaccharide deacetylase
OIO65_02765	COG0463	Glycosyl transferase, family 2
OIO65_02770	COG0438	transferase activity, transferring glycosyl groups
OIO65_02835	COG1960	acyl-CoA dehydrogenase activity
OIO65_02840	COG1960	acyl-CoA dehydrogenase activity
OIO65_02850	COG2205	protein histidine kinase activity
OIO65_02855	COG0745	RESPONSE REGULATOR receiver
OIO65_02860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OIO65_02875	COG0584	glycerophosphoryl diester phosphodiesterase
OIO65_02880	COG2096	Adenosyltransferase
OIO65_02930	COG0285	dihydrofolate synthase activity
OIO65_02950	COG0450	alkyl hydroperoxide reductase
OIO65_02965	COG0477	Major facilitator Superfamily
OIO65_02970	COG1272	protein, Hemolysin III
OIO65_03000	COG0183	Belongs to the thiolase family
OIO65_03005	COG2207	Transcriptional regulator
OIO65_03025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO65_03045	COG0183	Belongs to the thiolase family
OIO65_03055	COG2885	chlorophyll binding
OIO65_03055	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OIO65_03065	COG1690	Belongs to the RtcB family
OIO65_03070	COG0833	amino acid
OIO65_03080	COG2233	PERMEase
OIO65_03085	COG1217	gtp-binding protein TYPA
OIO65_03110	COG2094	Belongs to the DNA glycosylase MPG family
OIO65_03115	COG4772	TonB-dependent receptor
OIO65_03120	COG1902	pentaerythritol trinitrate reductase activity
OIO65_03135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO65_03140	COG0354	folic acid binding
OIO65_03150	COG3189	MarR family transcriptional regulator
OIO65_03155	COG2824	Alkylphosphonate utilization operon protein PhnA
OIO65_03160	COG3422	double-strand break repair
OIO65_03200	COG0840	transmembrane signaling receptor activity
OIO65_03225	COG5510	response to toxic substance
OIO65_03235	COG2832	Protein of unknown function (DUF454)
OIO65_03240	COG1376	ErfK ybiS ycfS ynhG family protein
OIO65_03290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OIO65_03300	COG1289	transmembrane transporter activity
OIO65_03305	COG2814	Major facilitator Superfamily
OIO65_03325	COG1115	amino acid carrier protein
OIO65_03330	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO65_03335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO65_03340	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OIO65_03365	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO65_03375	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO65_03380	COG1077	Cell shape determining protein MreB Mrl
OIO65_03385	COG1792	Involved in formation and maintenance of cell shape
OIO65_03390	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OIO65_03395	COG0424	maF-like protein
OIO65_03400	COG1530	ribonuclease E activity
OIO65_03410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO65_03420	COG0560	Phosphoserine phosphatase
OIO65_03430	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO65_03455	COG2207	Transcriptional regulator
OIO65_03500	COG1113	amino acid transport
OIO65_03505	COG2828	Protein conserved in bacteria
OIO65_03510	COG0142	geranyltranstransferase activity
OIO65_03515	COG2315	Protein conserved in bacteria
OIO65_03530	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO65_03550	COG2194	sulfuric ester hydrolase activity
OIO65_03555	COG0745	RESPONSE REGULATOR receiver
OIO65_03560	COG0642	Histidine kinase
OIO65_03575	COG0004	ammonium transporteR
OIO65_03580	COG0583	DNA-binding transcription factor activity
OIO65_03600	COG0525	valine-tRNA ligase activity
OIO65_03610	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_03620	COG0393	Putative heavy-metal-binding
OIO65_03625	COG0393	Putative heavy-metal-binding
OIO65_03630	COG1538	Outer membrane efflux protein
OIO65_03640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO65_03675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OIO65_03690	COG1648	precorrin-2 dehydrogenase activity
OIO65_03690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIO65_03695	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIO65_03700	COG1733	regulation of RNA biosynthetic process
OIO65_03710	COG0531	amino acid
OIO65_03725	COG0321	lipoyl(octanoyl) transferase activity
OIO65_03730	COG2921	Belongs to the UPF0250 family
OIO65_03765	COG2009	succinate dehydrogenase
OIO65_03770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OIO65_03775	COG1053	succinate dehydrogenase
OIO65_03780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIO65_03805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO65_03825	COG2354	Protein conserved in bacteria
OIO65_03830	COG2321	neutral zinc metallopeptidase
OIO65_03850	COG2843	Capsule synthesis protein
OIO65_03865	COG0589	response to stress
OIO65_03885	COG0505	Belongs to the CarA family
OIO65_03910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO65_03915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIO65_03965	COG0477	Major facilitator Superfamily
OIO65_03970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIO65_03985	COG1597	lipid kinase activity
OIO65_03990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO65_04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO65_04020	COG0584	glycerophosphoryl diester phosphodiesterase
OIO65_04040	COG0741	lytic transglycosylase activity
OIO65_04060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIO65_04075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO65_04100	COG3811	Belongs to the UPF0386 family
OIO65_04125	COG0778	Nitroreductase
OIO65_04140	COG1929	Belongs to the glycerate kinase type-1 family
OIO65_04145	COG0243	molybdopterin cofactor binding
OIO65_04150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIO65_04155	COG3339	Conserved Protein
OIO65_04165	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OIO65_04180	COG1113	amino acid transport
OIO65_04190	COG0019	diaminopimelate decarboxylase activity
OIO65_04200	COG2267	carboxylic ester hydrolase activity
OIO65_04205	COG1280	lysine exporter protein (LysE YggA)
OIO65_04210	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO65_04240	COG0463	Glycosyl transferase, family 2
OIO65_04260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO65_04295	COG4591	ABC-type transport system involved in lipoprotein release permease component
OIO65_04300	COG1136	(ABC) transporter
OIO65_04305	COG0658	competence protein
OIO65_04305	COG2333	competence protein COMEC
OIO65_04315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIO65_04315	COG0616	signal peptide processing
OIO65_04320	COG0596	Alpha beta hydrolase
OIO65_04325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIO65_04335	COG0628	permease
OIO65_04370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO65_04390	COG0823	Involved in the tonB-independent uptake of proteins
OIO65_04410	COG0824	Thioesterase
OIO65_04415	COG1473	amidohydrolase
OIO65_04435	COG0047	phosphoribosylformylglycinamidine synthase activity
OIO65_04435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIO65_04440	COG2814	Major facilitator Superfamily
OIO65_04455	COG1024	Enoyl-CoA hydratase
OIO65_04460	COG1051	belongs to the nudix hydrolase family
OIO65_04460	COG1056	cytidyltransferase-related domain
OIO65_04470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OIO65_04485	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OIO65_04500	COG4625	pathogenesis
OIO65_04505	COG0583	DNA-binding transcription factor activity
OIO65_04510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OIO65_04515	COG4208	sulfate ABC transporter
OIO65_04520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIO65_04530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OIO65_04535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIO65_04540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIO65_04560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO65_04570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIO65_04580	COG0681	Belongs to the peptidase S26 family
OIO65_04595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIO65_04605	COG1381	Involved in DNA repair and RecF pathway recombination
OIO65_04610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OIO65_04620	COG4221	oxidoreductase activity
OIO65_04650	COG0443	Heat shock 70 kDa protein
OIO65_04660	COG0436	Aminotransferase
OIO65_04680	COG0556	nucleotide-excision repair
OIO65_04735	COG2070	2-Nitropropane dioxygenase
OIO65_04750	COG1252	NADH dehydrogenase
OIO65_04755	COG1686	Belongs to the peptidase S11 family
OIO65_04770	COG1187	pseudouridine synthase activity
OIO65_04965	COG4695	Portal protein
OIO65_05100	COG0582	viral genome integration into host DNA
OIO65_05125	COG0477	Major facilitator Superfamily
OIO65_05130	COG0583	DNA-binding transcription factor activity
OIO65_05135	COG1823	symporter activity
OIO65_05145	COG0612	Peptidase, M16
OIO65_05170	COG0352	thiamine-phosphate diphosphorylase activity
OIO65_05205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO65_05220	COG1309	transcriptional regulator
OIO65_05230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO65_05235	COG0076	glutamate decarboxylase activity
OIO65_05245	COG1522	sequence-specific DNA binding
OIO65_05250	COG3961	Belongs to the TPP enzyme family
OIO65_05255	COG1113	amino acid transport
OIO65_05260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIO65_05265	COG0573	inorganic phosphate transmembrane transporter activity
OIO65_05275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIO65_05280	COG0616	signal peptide processing
OIO65_05315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OIO65_05320	COG1686	Belongs to the peptidase S11 family
OIO65_05345	COG0583	DNA-binding transcription factor activity
OIO65_05350	COG1067	ATP-dependent peptidase activity
OIO65_05375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OIO65_05400	COG1966	Carbon starvation protein
OIO65_05405	COG2879	small protein
OIO65_05445	COG1335	isochorismatase
OIO65_05450	COG0583	DNA-binding transcription factor activity
OIO65_05465	COG0596	Alpha beta hydrolase
OIO65_05475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO65_05485	COG2130	NADP-dependent
OIO65_05515	COG1741	Belongs to the pirin family
OIO65_05525	COG2964	Protein conserved in bacteria
OIO65_05540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO65_05550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO65_05555	COG4605	iron ion homeostasis
OIO65_05560	COG4604	ABC transporter, ATP-binding protein
OIO65_05565	COG4607	ABC-type enterochelin transport system periplasmic component
OIO65_05570	COG4774	siderophore transport
OIO65_05580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO65_05585	COG1021	2,3-dihydroxybenzoate-AMP ligase
OIO65_05590	COG3433	isochorismatase activity
OIO65_05590	COG1535	isochorismatase
OIO65_05605	COG1132	(ABC) transporter
OIO65_05610	COG1132	(ABC) transporter
OIO65_05615	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OIO65_05620	COG2977	Belongs to the P-Pant transferase superfamily
OIO65_05640	COG3739	integral membrane protein
OIO65_05660	COG0302	gtp cyclohydrolase
OIO65_05670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIO65_05700	COG0308	aminopeptidase N
OIO65_05705	COG0512	Glutamine amidotransferase of anthranilate synthase
OIO65_05720	COG0174	glutamine synthetase
OIO65_05730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OIO65_05765	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIO65_05770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIO65_05775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO65_05795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO65_05800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIO65_05805	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIO65_05820	COG1960	acyl-CoA dehydrogenase activity
OIO65_05825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO65_05830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO65_05840	COG2223	nitrite transmembrane transporter activity
OIO65_05860	COG0024	Methionine aminopeptidase
OIO65_05865	COG0052	Belongs to the universal ribosomal protein uS2 family
OIO65_05880	COG2207	Transcriptional regulator
OIO65_05905	COG2951	lytic endotransglycosylase activity
OIO65_05910	COG0772	Belongs to the SEDS family
OIO65_05925	COG0842	Transport permease protein
OIO65_05930	COG1131	(ABC) transporter
OIO65_05975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO65_05990	COG4215	(ABC) transporter
OIO65_05995	COG4160	amino acid transport
OIO65_06000	COG4598	ABC transporter
OIO65_06010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO65_06015	COG0826	peptidase U32
OIO65_06020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO65_06035	COG1720	tRNA m6t6A37 methyltransferase activity
OIO65_06045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OIO65_06060	COG0642	Histidine kinase
OIO65_06070	COG0494	nUDIX hydrolase
OIO65_06080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIO65_06085	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIO65_06090	COG3139	Protein of unknown function (DUF1315)
OIO65_06100	COG1301	dicarboxylic acid transport
OIO65_06105	COG1960	acyl-CoA dehydrogenase activity
OIO65_06110	COG2819	hydrolase of the alpha beta superfamily
OIO65_06120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIO65_06130	COG2195	Cleaves the N-terminal amino acid of tripeptides
OIO65_06150	COG1690	Belongs to the RtcB family
OIO65_06155	COG1234	tRNA 3'-trailer cleavage
OIO65_06160	COG4650	regulator
OIO65_06190	COG2363	Small membrane protein
OIO65_06215	COG0513	Belongs to the DEAD box helicase family
OIO65_06225	COG0778	Nitroreductase
OIO65_06255	COG1286	toxin biosynthetic process
OIO65_06280	COG4783	chaperone-mediated protein folding
OIO65_06285	COG1610	YqeY-like protein
OIO65_06315	COG0515	serine threonine protein kinase
OIO65_06315	COG2815	serine threonine protein kinase
OIO65_06385	COG3111	PFAM Bacterial OB fold (BOF) protein
OIO65_06410	COG3243	poly(R)-hydroxyalkanoic acid synthase
OIO65_06415	COG0786	glutamate:sodium symporter activity
OIO65_06425	COG2186	Transcriptional regulator
OIO65_06440	COG0477	Major facilitator Superfamily
OIO65_06470	COG2995	paraquat-inducible protein a
OIO65_06475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIO65_06475	COG3008	intermembrane lipid transfer
OIO65_06485	COG1794	racemase activity, acting on amino acids and derivatives
OIO65_06515	COG1301	dicarboxylic acid transport
OIO65_06525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO65_06530	COG2011	ABC-type metal ion transport system permease component
OIO65_06535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO65_06540	COG1464	Belongs to the NlpA lipoprotein family
OIO65_06545	COG0151	Belongs to the GarS family
OIO65_06550	COG0138	bifunctional purine biosynthesis protein purh
OIO65_06555	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OIO65_06585	COG2308	Evidence 4 Homologs of previously reported genes of
OIO65_06595	COG1305	Transglutaminase-like
OIO65_06605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIO65_06610	COG0305	Participates in initiation and elongation during chromosome replication
OIO65_06635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OIO65_06645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIO65_06650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIO65_06675	COG0726	polysaccharide deacetylase
OIO65_06675	COG1649	PFAM Uncharacterised BCR, COG1649
OIO65_06680	COG1215	transferase activity, transferring glycosyl groups
OIO65_06685	COG3658	cytochrome
OIO65_06695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO65_06710	COG0583	DNA-binding transcription factor activity
OIO65_06730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO65_06735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO65_06750	COG1960	acyl-CoA dehydrogenase activity
OIO65_06755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO65_06760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO65_06775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OIO65_06785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIO65_06790	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIO65_06805	COG0745	RESPONSE REGULATOR receiver
OIO65_06810	COG0174	glutamine synthetase
OIO65_06830	COG0729	surface antigen
OIO65_06855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO65_06860	COG2814	Major facilitator Superfamily
OIO65_06875	COG0583	DNA-binding transcription factor activity
OIO65_06890	COG1187	pseudouridine synthase activity
OIO65_06910	COG0802	atpase or kinase
OIO65_06915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIO65_06925	COG1923	regulation of RNA biosynthetic process
OIO65_06930	COG0697	spore germination
OIO65_06955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO65_06960	COG0519	Catalyzes the synthesis of GMP from XMP
OIO65_06960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO65_06965	COG4302	ethanolamine ammonia-lyase activity
OIO65_06970	COG4303	Ethanolamine ammonia lyase large subunit
OIO65_06975	COG0531	amino acid
OIO65_06995	COG1454	alcohol dehydrogenase
OIO65_07000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO65_07010	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OIO65_07030	COG0308	aminopeptidase N
OIO65_07050	COG1605	Chorismate mutase
OIO65_07070	COG1309	transcriptional regulator
OIO65_07080	COG0668	transmembrane transport
OIO65_07110	COG4773	Receptor
OIO65_07130	COG0488	(ABC) transporter
OIO65_07135	COG0589	response to stress
OIO65_07160	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIO65_07170	COG3135	benzoate transporter
OIO65_07175	COG1522	sequence-specific DNA binding
OIO65_07185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIO65_07190	COG0583	DNA-binding transcription factor activity
OIO65_07200	COG0183	Belongs to the thiolase family
OIO65_07210	COG2030	dehydratase
OIO65_07215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO65_07230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIO65_07245	COG0824	Thioesterase
OIO65_07250	COG1454	alcohol dehydrogenase
OIO65_07260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIO65_07280	COG0069	glutamate synthase activity
OIO65_07300	COG2814	Major facilitator Superfamily
OIO65_07315	COG0511	ligase activity, forming carbon-carbon bonds
OIO65_07335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO65_07335	COG1116	anion transmembrane transporter activity
OIO65_07340	COG0745	RESPONSE REGULATOR receiver
OIO65_07350	COG2146	nitrite reductase [NAD(P)H] activity
OIO65_07350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO65_07355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO65_07360	COG0243	molybdopterin cofactor binding
OIO65_07370	COG0243	molybdopterin cofactor binding
OIO65_07390	COG0315	cyclic pyranopterin monophosphate synthase activity
OIO65_07390	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIO65_07405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO65_07410	COG0697	spore germination
OIO65_07430	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OIO65_07435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO65_07490	COG2204	response regulator
OIO65_07495	COG3852	Histidine kinase
OIO65_07515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIO65_07520	COG0575	Belongs to the CDS family
OIO65_07535	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO65_07555	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO65_07570	COG2137	regulation of response to DNA damage stimulus
OIO65_07580	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OIO65_07585	COG1011	Hydrolase
OIO65_07610	COG1522	sequence-specific DNA binding
OIO65_07620	COG1113	amino acid transport
OIO65_07640	COG0659	secondary active sulfate transmembrane transporter activity
OIO65_07645	COG2135	peptidase activity
OIO65_07660	COG3300	MHYT domain
OIO65_07660	COG5001	Diguanylate cyclase
OIO65_07680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO65_07680	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIO65_07680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO65_07685	COG1105	Belongs to the carbohydrate kinase PfkB family
OIO65_07690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIO65_07690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO65_07720	COG0024	Methionine aminopeptidase
OIO65_07725	COG0583	DNA-binding transcription factor activity
OIO65_07735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OIO65_07740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO65_07745	COG0516	GMP reductase activity
OIO65_07745	COG0517	IMP dehydrogenase activity
OIO65_07770	COG0552	protein localization to endoplasmic reticulum
OIO65_07780	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OIO65_07790	COG4890	Cyd operon protein YbgT
OIO65_07795	COG1294	oxidase, subunit
OIO65_07810	COG1585	Membrane protein implicated in regulation of membrane protease activity
OIO65_07820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIO65_07825	COG4774	siderophore transport
OIO65_07840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIO65_07845	COG0569	domain protein
OIO65_07850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO65_07880	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIO65_07885	COG0542	response to heat
OIO65_07895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO65_07910	COG1902	pentaerythritol trinitrate reductase activity
OIO65_07910	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO65_07955	COG2323	membrane
OIO65_07960	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OIO65_07970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO65_07975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO65_07980	COG0183	Belongs to the thiolase family
OIO65_07985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIO65_07990	COG0596	Alpha beta hydrolase
OIO65_07995	COG2271	Major facilitator Superfamily
OIO65_08000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO65_08005	COG3485	protocatechuate 3,4-dioxygenase
OIO65_08010	COG3485	protocatechuate 3,4-dioxygenase
OIO65_08015	COG0710	3-dehydroquinate dehydratase activity
OIO65_08020	COG3420	alginic acid biosynthetic process
OIO65_08025	COG3659	wide pore channel activity
OIO65_08030	COG4993	Dehydrogenase
OIO65_08040	COG2391	methyltransferase activity
OIO65_08055	COG1414	Transcriptional regulator
OIO65_08060	COG0583	DNA-binding transcription factor activity
OIO65_08065	COG1960	acyl-CoA dehydrogenase activity
OIO65_08090	COG2814	Major facilitator Superfamily
OIO65_08100	COG0154	amidase activity
OIO65_08120	COG4638	Rieske (2fe-2S)
OIO65_08130	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_08140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO65_08150	COG3733	amine oxidase
OIO65_08160	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_08170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO65_08175	COG0183	Belongs to the thiolase family
OIO65_08180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO65_08185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO65_08195	COG4829	muconolactone delta-isomerase
OIO65_08200	COG4948	Mandelate Racemase Muconate Lactonizing
OIO65_08205	COG0583	DNA-binding transcription factor activity
OIO65_08215	COG2186	Transcriptional regulator
OIO65_08235	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_08240	COG3231	kanamycin kinase activity
OIO65_08255	COG1960	acyl-CoA dehydrogenase activity
OIO65_08260	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_08265	COG3829	transcription factor binding
OIO65_08275	COG3162	membrane
OIO65_08290	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_08305	COG0753	catalase activity
OIO65_08330	COG1846	Transcriptional regulator
OIO65_08335	COG1902	pentaerythritol trinitrate reductase activity
OIO65_08335	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO65_08370	COG1309	transcriptional regulator
OIO65_08380	COG1335	isochorismatase
OIO65_08385	COG0583	DNA-binding transcription factor activity
OIO65_08395	COG0475	glutathione-regulated potassium exporter activity
OIO65_08395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO65_08405	COG1473	amidohydrolase
OIO65_08460	COG2188	Transcriptional regulator
OIO65_08475	COG0583	DNA-binding transcription factor activity
OIO65_08510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO65_08530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO65_08550	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_08565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO65_08570	COG2814	Major facilitator Superfamily
OIO65_08580	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO65_08590	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_08595	COG3384	dioxygenase
OIO65_08605	COG3971	2-oxopent-4-enoate hydratase activity
OIO65_08620	COG0477	Major facilitator Superfamily
OIO65_08625	COG1960	acyl-CoA dehydrogenase activity
OIO65_08630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO65_08635	COG1846	Transcriptional regulator
OIO65_08640	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_08645	COG0129	dihydroxy-acid dehydratase activity
OIO65_08655	COG0583	DNA-binding transcription factor activity
OIO65_08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO65_08670	COG2084	Dehydrogenase
OIO65_08675	COG2207	Transcriptional regulator
OIO65_08690	COG1064	alcohol dehydrogenase
OIO65_08700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO65_08705	COG1120	ATPase activity
OIO65_08725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO65_08775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OIO65_08800	COG2814	Major facilitator Superfamily
OIO65_08805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO65_08805	COG3320	Male sterility
OIO65_08835	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_08845	COG2207	Transcriptional regulator
OIO65_08855	COG2205	protein histidine kinase activity
OIO65_08860	COG0745	RESPONSE REGULATOR receiver
OIO65_08865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO65_08870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO65_08895	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO65_08905	COG0753	catalase activity
OIO65_08925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO65_08985	COG1535	isochorismatase
OIO65_08985	COG3433	isochorismatase activity
OIO65_08990	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_08995	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OIO65_09000	COG4149	molybdate abc transporter
OIO65_09005	COG0725	ABC transporter, periplasmic molybdate-binding protein
OIO65_09015	COG4638	Rieske (2fe-2S)
OIO65_09020	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO65_09025	COG0543	2 iron, 2 sulfur cluster binding
OIO65_09025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO65_09040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO65_09050	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_09065	COG2207	Transcriptional regulator
OIO65_09070	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_09075	COG2610	gluconate transmembrane transporter activity
OIO65_09085	COG0583	DNA-binding transcription factor activity
OIO65_09100	COG2031	fatty acid transporter
OIO65_09105	COG0183	Belongs to the thiolase family
OIO65_09110	COG0583	DNA-binding transcription factor activity
OIO65_09115	COG0583	DNA-binding transcription factor activity
OIO65_09130	COG1027	Aspartate ammonia-lyase
OIO65_09140	COG0477	Major facilitator Superfamily
OIO65_09160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO65_09165	COG4521	taurine ABC transporter
OIO65_09180	COG2188	Transcriptional regulator
OIO65_09190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIO65_09195	COG1733	regulation of RNA biosynthetic process
OIO65_09200	COG2207	Transcriptional regulator
OIO65_09200	COG3708	Transcriptional regulator
OIO65_09215	COG0730	response to heat
OIO65_09230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO65_09230	COG3453	Protein conserved in bacteria
OIO65_09240	COG3781	membrane
OIO65_09245	COG1063	alcohol dehydrogenase
OIO65_09255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO65_09260	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO65_09265	COG0022	dehydrogenase e1 component
OIO65_09270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OIO65_09275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO65_09290	COG3706	GGDEF domain
OIO65_09305	COG0133	tryptophan synthase activity
OIO65_09315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO65_09350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIO65_09375	COG2226	methyltransferase
OIO65_09430	COG0842	Transport permease protein
OIO65_09435	COG0842	Transport permease protein
OIO65_09440	COG1131	(ABC) transporter
OIO65_09455	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO65_09480	COG0730	response to heat
OIO65_09485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO65_09500	COG0406	alpha-ribazole phosphatase activity
OIO65_09505	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIO65_09520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO65_09550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO65_09560	COG4264	IucA IucC family
OIO65_09565	COG4264	IucA IucC family
OIO65_09570	COG2814	Major facilitator Superfamily
OIO65_09585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIO65_09600	COG1960	acyl-CoA dehydrogenase activity
OIO65_09605	COG1960	acyl-CoA dehydrogenase activity
OIO65_09610	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO65_09615	COG2207	Transcriptional regulator
OIO65_09620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO65_09625	COG0776	regulation of translation
OIO65_09650	COG0822	iron-sulfur transferase activity
OIO65_09655	COG0316	Belongs to the HesB IscA family
OIO65_09685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO65_09705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO65_09710	COG0702	epimerase
OIO65_09745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIO65_09755	COG0339	signal peptide processing
OIO65_09765	COG4166	transmembrane transport
OIO65_09800	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIO65_09805	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OIO65_09835	COG0776	regulation of translation
OIO65_09900	COG0084	hydrolase, TatD family'
OIO65_09920	COG1663	tetraacyldisaccharide 4'-kinase activity
OIO65_09925	COG1132	(ABC) transporter
OIO65_09935	COG0811	peptide transport
OIO65_09940	COG1475	DNA binding
OIO65_09945	COG1192	Involved in chromosome partitioning
OIO65_09955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIO65_09970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO65_09975	COG0191	fructose-bisphosphate aldolase activity
OIO65_09995	COG0424	maF-like protein
OIO65_10000	COG2850	peptidyl-arginine hydroxylation
OIO65_10010	COG0640	Transcriptional regulator
OIO65_10020	COG3619	membrane
OIO65_10025	COG3122	Protein conserved in bacteria
OIO65_10030	COG1132	(ABC) transporter
OIO65_10050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIO65_10055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO65_10065	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO65_10065	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO65_10065	COG0506	proline dehydrogenase activity
OIO65_10070	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIO65_10085	COG3698	Phosphodiester glycosidase
OIO65_10095	COG2353	YceI-like domain
OIO65_10105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIO65_10150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIO65_10150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIO65_10175	COG3539	Fimbrial protein
OIO65_10180	COG3121	Chaperone
OIO65_10205	COG0697	spore germination
OIO65_10215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO65_10225	COG0583	DNA-binding transcription factor activity
OIO65_10245	COG1309	transcriptional regulator
OIO65_10260	COG1522	sequence-specific DNA binding
OIO65_10270	COG1126	abc transporter atp-binding protein
OIO65_10275	COG0765	amino acid transport
OIO65_10280	COG0765	amino acid transport
OIO65_10310	COG1464	Belongs to the NlpA lipoprotein family
OIO65_10320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO65_10325	COG2011	ABC-type metal ion transport system permease component
OIO65_10330	COG0012	GTP binding
OIO65_10355	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO65_10395	COG0386	Belongs to the glutathione peroxidase family
OIO65_10405	COG0436	Aminotransferase
OIO65_10410	COG1301	dicarboxylic acid transport
OIO65_10445	COG3634	alkyl hydroperoxide reductase activity
OIO65_10460	COG0583	DNA-binding transcription factor activity
OIO65_10465	COG0798	PFAM Bile acid sodium symporter
OIO65_10470	COG0640	Transcriptional regulator
OIO65_10485	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIO65_10495	COG0583	DNA-binding transcription factor activity
OIO65_10505	COG1953	Uracil, thiamine, allantoin
OIO65_10515	COG2175	clavaminate synthase activity
OIO65_10520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO65_10540	COG4521	taurine ABC transporter
OIO65_10550	COG0477	Major facilitator Superfamily
OIO65_10570	COG1271	oxidase subunit
OIO65_10575	COG1294	oxidase, subunit
OIO65_10585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO65_10605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OIO65_10625	COG3052	prosthetic group binding
OIO65_10630	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OIO65_10640	COG0583	DNA-binding transcription factor activity
OIO65_10650	COG2814	Major facilitator Superfamily
OIO65_10670	COG1346	cytolysis
OIO65_10680	COG0583	DNA-binding transcription factor activity
OIO65_10685	COG0625	glutathione transferase activity
OIO65_10690	COG0625	glutathione transferase activity
OIO65_10695	COG0583	DNA-binding transcription factor activity
OIO65_10700	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_10710	COG1045	serine acetyltransferase
OIO65_10715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO65_10720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIO65_10730	COG1280	lysine exporter protein (LysE YggA)
OIO65_10745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO65_10750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO65_10755	COG1126	abc transporter atp-binding protein
OIO65_10760	COG0765	amino acid transport
OIO65_10765	COG0765	amino acid transport
OIO65_10785	COG2205	protein histidine kinase activity
OIO65_10785	COG0784	Response regulator, receiver
OIO65_10805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIO65_10825	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_10875	COG0583	DNA-binding transcription factor activity
OIO65_10895	COG0318	PFAM AMP-dependent synthetase and ligase
OIO65_10900	COG1309	transcriptional regulator
OIO65_10905	COG1960	acyl-CoA dehydrogenase activity
OIO65_10910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO65_10915	COG1024	Enoyl-CoA hydratase
OIO65_10920	COG4770	biotin carboxylase activity
OIO65_10930	COG0583	DNA-binding transcription factor activity
OIO65_10950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO65_10970	COG3842	ATPase activity
OIO65_10975	COG1840	ABC-type Fe3 transport system, periplasmic component
OIO65_10990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO65_10995	COG1414	Transcriptional regulator
OIO65_11005	COG0583	DNA-binding transcription factor activity
OIO65_11010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO65_11015	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_11025	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO65_11035	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_11040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO65_11045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO65_11050	COG2267	carboxylic ester hydrolase activity
OIO65_11070	COG3038	cytochrome b561
OIO65_11075	COG0753	catalase activity
OIO65_11080	COG2271	Major facilitator Superfamily
OIO65_11085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO65_11090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO65_11115	COG2207	Transcriptional regulator
OIO65_11125	COG1278	Cold shock
OIO65_11160	COG0556	nucleotide-excision repair
OIO65_11170	COG2050	protein possibly involved in aromatic compounds catabolism
OIO65_11180	COG3327	negative regulation of DNA-templated transcription, initiation
OIO65_11185	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OIO65_11190	COG0183	Belongs to the thiolase family
OIO65_11195	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO65_11200	COG1024	Enoyl-CoA hydratase
OIO65_11205	COG1024	Enoyl-CoA hydratase
OIO65_11210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO65_11215	COG2151	metal-sulfur cluster biosynthetic enzyme
OIO65_11220	COG3396	Phenylacetate-CoA oxygenase
OIO65_11225	COG3460	Phenylacetate-CoA oxygenase
OIO65_11230	COG3396	Phenylacetate-CoA oxygenase
OIO65_11235	COG2030	dehydratase
OIO65_11235	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_11240	COG1760	l-serine dehydratase
OIO65_11245	COG0531	amino acid
OIO65_11250	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_11275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO65_11295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO65_11305	COG0789	Transcriptional regulator
OIO65_11315	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OIO65_11330	COG2807	transmembrane transport
OIO65_11335	COG0590	tRNA wobble adenosine to inosine editing
OIO65_11465	COG1116	anion transmembrane transporter activity
OIO65_11470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO65_11480	COG0864	Transcriptional regulator
OIO65_11490	COG1733	regulation of RNA biosynthetic process
OIO65_11495	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO65_11500	COG0439	Biotin carboxylase
OIO65_11515	COG1063	alcohol dehydrogenase
OIO65_11525	COG1309	transcriptional regulator
OIO65_11565	COG0038	chloride channel
OIO65_11570	COG4770	biotin carboxylase activity
OIO65_11590	COG1914	H( )-stimulated, divalent metal cation uptake system
OIO65_11650	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO65_11675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO65_11680	COG1116	anion transmembrane transporter activity
OIO65_11685	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO65_11715	COG0598	Magnesium transport protein CorA
OIO65_11725	COG1560	Kdo2-lipid A biosynthetic process
OIO65_11735	COG5006	permease, DMT superfamily
OIO65_11740	COG1522	sequence-specific DNA binding
OIO65_11755	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OIO65_11765	COG4122	O-methyltransferase activity
OIO65_11800	COG1137	ATPase activity
OIO65_11805	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OIO65_11815	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OIO65_11820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OIO65_11820	COG0517	IMP dehydrogenase activity
OIO65_11860	COG2814	Major facilitator Superfamily
OIO65_11895	COG1278	Cold shock
OIO65_11900	COG1280	lysine exporter protein (LysE YggA)
OIO65_11930	COG1570	exodeoxyribonuclease VII activity
OIO65_11980	COG0583	DNA-binding transcription factor activity
OIO65_11990	COG4638	Rieske (2fe-2S)
OIO65_12000	COG0543	2 iron, 2 sulfur cluster binding
OIO65_12000	COG0633	Ferredoxin
OIO65_12005	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_12010	COG3135	benzoate transporter
OIO65_12015	COG2814	Major facilitator Superfamily
OIO65_12030	COG1643	Atp-dependent helicase
OIO65_12035	COG0450	alkyl hydroperoxide reductase
OIO65_12045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIO65_12055	COG3634	alkyl hydroperoxide reductase activity
OIO65_12075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIO65_12240	COG0625	glutathione transferase activity
OIO65_12250	COG2885	chlorophyll binding
OIO65_12285	COG0542	response to heat
OIO65_12300	COG1765	OsmC-like protein
OIO65_12315	COG0667	Aldo Keto reductase
OIO65_12330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIO65_12345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIO65_12355	COG0527	aspartate kinase activity
OIO65_12365	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIO65_12375	COG3038	cytochrome b561
OIO65_12380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIO65_12385	COG2252	PERMEase
OIO65_12395	COG2072	flavoprotein involved in K transport
OIO65_12410	COG1741	Belongs to the pirin family
OIO65_12415	COG1309	transcriptional regulator
OIO65_12425	COG0300	oxidoreductase activity
OIO65_12430	COG2072	flavoprotein involved in K transport
OIO65_12435	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIO65_12480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO65_12500	COG2814	Major facilitator Superfamily
OIO65_12505	COG1024	Enoyl-CoA hydratase
OIO65_12510	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_12520	COG1960	acyl-CoA dehydrogenase activity
OIO65_12545	COG2186	Transcriptional regulator
OIO65_12550	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_12560	COG4948	Mandelate Racemase Muconate Lactonizing
OIO65_12565	COG2271	Major facilitator Superfamily
OIO65_12570	COG2721	sulfolactate sulfo-lyase activity
OIO65_12575	COG0697	spore germination
OIO65_12620	COG1113	amino acid transport
OIO65_12640	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_12660	COG0531	amino acid
OIO65_12670	COG1113	amino acid transport
OIO65_12710	COG3209	COG3209 Rhs family protein
OIO65_12730	COG4269	membrane
OIO65_12745	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO65_12745	COG1902	pentaerythritol trinitrate reductase activity
OIO65_12755	COG4251	negative regulation of phosphorylation
OIO65_12755	COG5001	Diguanylate cyclase
OIO65_12755	COG2203	Gaf domain
OIO65_12755	COG3706	GGDEF domain
OIO65_12765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO65_12790	COG4172	Belongs to the ABC transporter superfamily
OIO65_12795	COG4239	(ABC) transporter, permease
OIO65_12800	COG4174	ABC transporter (Permease)
OIO65_12810	COG0741	lytic transglycosylase activity
OIO65_12810	COG1388	LysM domain
OIO65_12810	COG0741	lytic transglycosylase activity
OIO65_12810	COG1388	LysM domain
OIO65_12815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO65_12855	COG0583	DNA-binding transcription factor activity
OIO65_12860	COG1279	arginine transmembrane transporter activity
OIO65_12880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO65_12885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO65_12890	COG0006	proline dipeptidase activity
OIO65_12925	COG2194	sulfuric ester hydrolase activity
OIO65_13090	COG5410	chromosome segregation
OIO65_13270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIO65_13290	COG3384	dioxygenase
OIO65_13300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO65_13305	COG2878	Part of a membrane complex involved in electron transport
OIO65_13310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIO65_13335	COG0768	penicillin binding
OIO65_13340	COG0742	ribosomal rna small subunit methyltransferase
OIO65_13355	COG0830	nickel cation binding
OIO65_13365	COG0804	urea catabolic process
OIO65_13405	COG1253	flavin adenine dinucleotide binding
OIO65_13410	COG2851	Citrate transporter
OIO65_13460	COG1773	rubredoxin
OIO65_13465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO65_13475	COG0583	DNA-binding transcription factor activity
OIO65_13505	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OIO65_13510	COG4181	ATPase activity
OIO65_13555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIO65_13580	COG0306	phosphate transporter
OIO65_13590	COG3958	Transketolase
OIO65_13595	COG3959	Transketolase, thiamine diphosphate binding domain
OIO65_13600	COG2271	Major facilitator Superfamily
OIO65_13605	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_13610	COG0583	DNA-binding transcription factor activity
OIO65_13630	COG2207	Transcriptional regulator
OIO65_13635	COG2066	Belongs to the glutaminase family
OIO65_13640	COG0242	peptide deformylase activity
OIO65_13645	COG0477	Major facilitator Superfamily
OIO65_13655	COG0028	Belongs to the TPP enzyme family
OIO65_13670	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_13675	COG2267	carboxylic ester hydrolase activity
OIO65_13685	COG2271	Major facilitator Superfamily
OIO65_13690	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO65_13700	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_13720	COG1414	Transcriptional regulator
OIO65_13735	COG1024	Enoyl-CoA hydratase
OIO65_13745	COG1215	transferase activity, transferring glycosyl groups
OIO65_13750	COG0726	polysaccharide deacetylase
OIO65_13750	COG1649	PFAM Uncharacterised BCR, COG1649
OIO65_13760	COG4681	YaeQ
OIO65_13770	COG0523	cobalamin synthesis protein
OIO65_13780	COG1607	acyl-coa hydrolase
OIO65_13790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO65_13795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO65_13800	COG1309	transcriptional regulator
OIO65_13825	COG2040	homocysteine
OIO65_13830	COG0531	amino acid
OIO65_13885	COG1595	DNA-templated transcription, initiation
OIO65_13895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO65_13900	COG0477	Major facilitator Superfamily
OIO65_13910	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OIO65_13975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO65_14060	COG0592	DNA-directed DNA polymerase activity
OIO65_14100	COG2026	Addiction module toxin, RelE StbE family
OIO65_14320	COG1484	DNA-dependent DNA replication
OIO65_14405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO65_14485	COG0405	Gamma-glutamyltransferase
OIO65_14490	COG2814	Major facilitator Superfamily
OIO65_14500	COG2050	protein possibly involved in aromatic compounds catabolism
OIO65_14515	COG1090	epimerase
OIO65_14535	COG0420	3'-5' exonuclease activity
OIO65_14560	COG0735	belongs to the Fur family
OIO65_14565	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO65_14585	COG0121	glutamine amidotransferase
OIO65_14600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO65_14610	COG0210	DNA helicase
OIO65_14615	COG2885	chlorophyll binding
OIO65_14620	COG0204	Acyl-transferase
OIO65_14635	COG2894	cell division
OIO65_14650	COG1280	lysine exporter protein (LysE YggA)
OIO65_14655	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OIO65_14655	COG1674	ftsk spoiiie
OIO65_14660	COG0492	ferredoxin-NADP+ reductase activity
OIO65_14665	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OIO65_14675	COG0456	acetyltransferase
OIO65_14720	COG1981	membrane
OIO65_14735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO65_14735	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIO65_14755	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_14765	COG0657	acetylesterase activity
OIO65_14775	COG0473	3-isopropylmalate dehydrogenase activity
OIO65_14780	COG0583	DNA-binding transcription factor activity
OIO65_14810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO65_14835	COG0564	pseudouridine synthase activity
OIO65_14845	COG0358	DNA primase activity
OIO65_14860	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OIO65_14890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO65_14920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIO65_14930	COG0351	phosphomethylpyrimidine kinase
OIO65_14930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO65_14930	COG0352	thiamine-phosphate diphosphorylase activity
OIO65_14935	COG1652	LysM domain
OIO65_14960	COG1399	metal-binding, possibly nucleic acid-binding protein
OIO65_14965	COG3101	peptidyl-lysine hydroxylation
OIO65_14970	COG0009	L-threonylcarbamoyladenylate synthase
OIO65_14975	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIO65_14980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIO65_14995	COG4106	trans-aconitate 2-methyltransferase activity
OIO65_15010	COG0596	Alpha beta hydrolase
OIO65_15010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO65_15010	COG2226	methyltransferase
OIO65_15015	COG1877	trehalose-phosphatase activity
OIO65_15020	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OIO65_15025	COG2223	nitrite transmembrane transporter activity
OIO65_15045	COG1196	nuclear chromosome segregation
OIO65_15055	COG0730	response to heat
OIO65_15070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIO65_15080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO65_15130	COG0489	protein tyrosine kinase activity
OIO65_15140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO65_15140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO65_15170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO65_15175	COG2081	HI0933 family
OIO65_15185	COG0668	transmembrane transport
OIO65_15205	COG0583	DNA-binding transcription factor activity
OIO65_15230	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIO65_15235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO65_15265	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIO65_15305	COG0745	RESPONSE REGULATOR receiver
OIO65_15325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO65_15330	COG0697	spore germination
OIO65_15365	COG0477	Major facilitator Superfamily
OIO65_15375	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_15395	COG0384	phenazine biosynthesis protein PhzF
OIO65_15440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO65_15455	COG0583	DNA-binding transcription factor activity
OIO65_15465	COG0583	DNA-binding transcription factor activity
OIO65_15480	COG0583	DNA-binding transcription factor activity
OIO65_15485	COG1053	succinate dehydrogenase
OIO65_15495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO65_15500	COG2814	Major facilitator Superfamily
OIO65_15505	COG1960	acyl-CoA dehydrogenase activity
OIO65_15510	COG0583	DNA-binding transcription factor activity
OIO65_15515	COG1063	alcohol dehydrogenase
OIO65_15545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIO65_15550	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIO65_15555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO65_15575	COG2132	Multicopper oxidase
OIO65_15585	COG0561	phosphatase activity
OIO65_15590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIO65_15600	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO65_15615	COG1214	PFAM Peptidase M22, glycoprotease
OIO65_15685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIO65_15690	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIO65_15695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIO65_15755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO65_15765	COG1846	Transcriptional regulator
OIO65_15770	COG1764	response to oxidative stress
OIO65_15810	COG0037	tRNA processing
OIO65_15820	COG0248	Ppx GppA phosphatase
OIO65_15850	COG0072	phenylalanine-tRNA ligase activity
OIO65_15895	COG1238	metal cluster binding
OIO65_15900	COG0625	glutathione transferase activity
OIO65_15915	COG0318	PFAM AMP-dependent synthetase and ligase
OIO65_15920	COG3028	Belongs to the UPF0307 family
OIO65_15925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO65_15945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OIO65_15950	COG0617	tRNA 3'-terminal CCA addition
OIO65_15955	COG1555	photosystem II stabilization
OIO65_15960	COG3956	TIGRFAM MazG family protein
OIO65_15970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO65_15990	COG0784	Response regulator, receiver
OIO65_15990	COG5002	protein histidine kinase activity
OIO65_15990	COG2205	protein histidine kinase activity
OIO65_15995	COG1024	Enoyl-CoA hydratase
OIO65_16000	COG2084	Dehydrogenase
OIO65_16005	COG3622	Belongs to the hyi family
OIO65_16040	COG0697	spore germination
OIO65_16050	COG2814	Major facilitator Superfamily
OIO65_16060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO65_16130	COG4774	siderophore transport
OIO65_16145	COG1271	oxidase subunit
OIO65_16150	COG1294	oxidase, subunit
OIO65_16220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO65_16230	COG0583	DNA-binding transcription factor activity
OIO65_16240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OIO65_16250	COG0084	hydrolase, TatD family'
OIO65_16265	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIO65_16295	COG0440	acetolactate synthase activity
OIO65_16300	COG0028	Belongs to the TPP enzyme family
OIO65_16325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO65_16330	COG1136	(ABC) transporter
OIO65_16330	COG0577	efflux transmembrane transporter activity
OIO65_16335	COG1538	Outer membrane efflux protein
OIO65_16350	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIO65_16355	COG1162	GTPase activity
OIO65_16365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OIO65_16405	COG1426	Protein conserved in bacteria
OIO65_16440	COG0793	Belongs to the peptidase S41A family
OIO65_16455	COG2267	carboxylic ester hydrolase activity
OIO65_16465	COG1012	belongs to the aldehyde dehydrogenase family
OIO65_16470	COG3265	gluconokinase activity
OIO65_16480	COG0800	Aldolase
OIO65_16490	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIO65_16495	COG0280	phosphate acetyltransferase
OIO65_16495	COG0857	belongs to the CobB CobQ family
OIO65_16500	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO65_16500	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO65_16520	COG0740	serine-type endopeptidase activity
OIO65_16530	COG4774	siderophore transport
OIO65_16540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO65_16550	COG2813	Specifically methylates the guanine in position
OIO65_16550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO65_16650	COG0788	formyltetrahydrofolate deformylase activity
OIO65_16675	COG4651	solute:proton antiporter activity
OIO65_16675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO65_16695	COG0724	RNA recognition motif
OIO65_16700	COG0210	DNA helicase
OIO65_16725	COG1733	regulation of RNA biosynthetic process
OIO65_16735	COG2900	Belongs to the SlyX family
OIO65_16740	COG0488	(ABC) transporter
OIO65_16745	COG1280	lysine exporter protein (LysE YggA)
OIO65_16750	COG1560	Kdo2-lipid A biosynthetic process
OIO65_16760	COG1301	dicarboxylic acid transport
OIO65_16815	COG0473	3-isopropylmalate dehydrogenase activity
OIO65_16870	COG0583	DNA-binding transcription factor activity
OIO65_16880	COG0625	glutathione transferase activity
OIO65_16885	COG2378	regulation of single-species biofilm formation
OIO65_16890	COG0546	phosphoglycolate phosphatase activity
OIO65_16900	COG1530	ribonuclease E activity
OIO65_16905	COG0318	PFAM AMP-dependent synthetase and ligase
OIO65_16920	COG0583	DNA-binding transcription factor activity
OIO65_16925	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_16930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIO65_16940	COG0534	Mate efflux family protein
OIO65_16955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OIO65_16980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO65_16980	COG0493	'glutamate synthase
OIO65_16990	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OIO65_16995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO65_17010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO65_17020	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OIO65_17020	COG0644	oxidoreductase
OIO65_17030	COG0425	Belongs to the sulfur carrier protein TusA family
OIO65_17035	COG4535	Mg2 and Co2 transporter CorC
OIO65_17045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO65_17065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIO65_17070	COG0475	glutathione-regulated potassium exporter activity
OIO65_17070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO65_17085	COG0484	heat shock protein binding
OIO65_17090	COG0789	Transcriptional regulator
OIO65_17095	COG0598	Magnesium transport protein CorA
OIO65_17110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO65_17115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO65_17120	COG1074	ATP-dependent DNA helicase activity
OIO65_17125	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OIO65_17145	COG2226	methyltransferase
OIO65_17165	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIO65_17180	COG2111	Na H antiporter
OIO65_17180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO65_17185	COG1006	Multisubunit Na H antiporter MnhC subunit
OIO65_17190	COG0651	ATP synthesis coupled electron transport
OIO65_17195	COG1863	multisubunit Na H antiporter MnhE subunit
OIO65_17200	COG2212	antiporter activity
OIO65_17205	COG1320	monovalent cation:proton antiporter activity
OIO65_17220	COG0195	Participates in both transcription termination and antitermination
OIO65_17270	COG0237	dephospho-CoA kinase activity
OIO65_17280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO65_17295	COG0497	DNA recombination
OIO65_17305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIO65_17335	COG2169	Transcriptional regulator
OIO65_17335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO65_17340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIO65_17400	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIO65_17415	COG0326	Molecular chaperone. Has ATPase activity
OIO65_17430	COG2056	Na+-H+ antiporter family
OIO65_17530	COG0546	phosphoglycolate phosphatase activity
OIO65_17535	COG1716	ATPase activity
OIO65_17580	COG0181	hydroxymethylbilane synthase activity
OIO65_17590	COG3275	phosphorelay sensor kinase activity
OIO65_17610	COG1538	Outer membrane efflux protein
OIO65_17615	COG0697	spore germination
OIO65_17660	COG1061	Type III restriction enzyme res subunit
OIO65_17665	COG1002	Type II restriction enzyme, methylase subunits
OIO65_17675	COG0659	secondary active sulfate transmembrane transporter activity
OIO65_17680	COG0589	response to stress
OIO65_17725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO65_17730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OIO65_17735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO65_17740	COG0772	Belongs to the SEDS family
OIO65_17765	COG4974	Belongs to the 'phage' integrase family
OIO65_17770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO65_17780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIO65_17790	COG2197	response regulator
OIO65_17805	COG0793	Belongs to the peptidase S41A family
OIO65_17810	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIO65_17815	COG0795	lipopolysaccharide-transporting ATPase activity
OIO65_17855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO65_17855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO65_17865	COG0004	ammonium transporteR
OIO65_17870	COG0347	Belongs to the P(II) protein family
OIO65_17905	COG1061	Type III restriction enzyme res subunit
OIO65_17910	COG1002	Type II restriction enzyme, methylase subunits
OIO65_17925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIO65_17940	COG0318	PFAM AMP-dependent synthetase and ligase
OIO65_17950	COG0477	Major facilitator Superfamily
OIO65_17955	COG2860	membrane
OIO65_17965	COG1253	flavin adenine dinucleotide binding
OIO65_17975	COG0477	Major facilitator Superfamily
OIO65_17980	COG3757	hydrolase, family 25
OIO65_17985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO65_18025	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIO65_18035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIO65_18105	COG0758	DNA mediated transformation
OIO65_18115	COG0697	spore germination
OIO65_18120	COG1309	transcriptional regulator
OIO65_18135	COG0386	Belongs to the glutathione peroxidase family
OIO65_18200	COG1121	(ABC) transporter
OIO65_18205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIO65_18210	COG1280	lysine exporter protein (LysE YggA)
OIO65_18215	COG2837	iron assimilation
OIO65_18225	COG0281	malic enzyme
OIO65_18270	COG0519	Catalyzes the synthesis of GMP from XMP
OIO65_18270	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO65_18275	COG4399	Belongs to the UPF0754 family
OIO65_18280	COG2259	Doxx family
OIO65_18285	COG0586	Pfam SNARE associated Golgi protein
OIO65_18300	COG1192	Involved in chromosome partitioning
OIO65_18310	COG0271	Belongs to the BolA IbaG family
OIO65_18330	COG2267	carboxylic ester hydrolase activity
OIO65_18350	COG3321	synthase
OIO65_18350	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OIO65_18350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIO65_18350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO65_18355	COG1960	acyl-CoA dehydrogenase activity
OIO65_18365	COG2197	response regulator
OIO65_18375	COG3916	Acyl-homoserine-lactone synthase
OIO65_18380	COG0477	Major facilitator Superfamily
OIO65_18385	COG1024	Enoyl-CoA hydratase
OIO65_18390	COG1024	Enoyl-CoA hydratase
OIO65_18395	COG1960	acyl-CoA dehydrogenase activity
OIO65_18400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO65_18420	COG1113	amino acid transport
OIO65_18425	COG1113	amino acid transport
OIO65_18430	COG0251	oxidation-reduction process
OIO65_18470	COG0564	pseudouridine synthase activity
OIO65_18500	COG1051	belongs to the nudix hydrolase family
OIO65_18525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIO65_18540	COG1802	Transcriptional regulator
OIO65_18550	COG1448	Aminotransferase
OIO65_18555	COG0277	FAD linked oxidase domain protein
OIO65_18565	COG2186	Transcriptional regulator
OIO65_18575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO65_18580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO65_18595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIO65_18605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OIO65_18615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OIO65_18620	COG0438	transferase activity, transferring glycosyl groups
OIO65_18630	COG0438	transferase activity, transferring glycosyl groups
OIO65_18650	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OIO65_18680	COG0728	peptidoglycan biosynthetic process
OIO65_18685	COG3023	N-Acetylmuramoyl-L-alanine amidase
OIO65_18720	COG1017	nitric oxide dioxygenase activity
OIO65_18720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO65_18745	COG0546	phosphoglycolate phosphatase activity
OIO65_18750	COG1028	Short-chain dehydrogenase reductase Sdr
OIO65_18770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO65_18775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO65_18780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO65_18785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO65_18790	COG1116	anion transmembrane transporter activity
OIO65_18795	COG1309	transcriptional regulator
OIO65_18800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO65_18810	COG0196	riboflavin kinase activity
OIO65_18815	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIO65_18825	COG1047	Peptidyl-prolyl cis-trans
OIO65_18865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIO65_18870	COG0657	acetylesterase activity
OIO65_18890	COG0583	DNA-binding transcription factor activity
OIO65_18920	COG2951	lytic endotransglycosylase activity
OIO65_18925	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIO65_18940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIO65_18950	COG0671	phosphoesterase, PA-phosphatase related
OIO65_18955	COG0861	Integral membrane protein TerC family
OIO65_18965	COG0754	glutathionylspermidine amidase activity
OIO65_18975	COG0402	S-adenosylhomocysteine deaminase activity
OIO65_18990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO65_18995	COG1230	cation diffusion facilitator family transporter
OIO65_19010	COG0706	membrane insertase activity
OIO65_19060	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
OIO65_19065	COG0627	Serine hydrolase involved in the detoxification of formaldehyde