locus-tag	class	description
OIO78_00010	COG0592	DNA-directed DNA polymerase activity
OIO78_00020	COG0187	DNA topoisomerase II activity
OIO78_00030	COG0586	Pfam SNARE associated Golgi protein
OIO78_00035	COG0488	(ABC) transporter
OIO78_00060	COG0596	Alpha beta hydrolase
OIO78_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OIO78_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO78_00110	COG0733	neurotransmitter:sodium symporter activity
OIO78_00150	COG2233	PERMEase
OIO78_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO78_00200	COG2814	Major facilitator Superfamily
OIO78_00205	COG0656	L-ascorbic acid biosynthetic process
OIO78_00210	COG0583	DNA-binding transcription factor activity
OIO78_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO78_00230	COG1064	alcohol dehydrogenase
OIO78_00235	COG2818	Glycosylase
OIO78_00250	COG1194	a g-specific adenine glycosylase
OIO78_00270	COG2983	Belongs to the UPF0260 family
OIO78_00280	COG3121	Chaperone
OIO78_00285	COG3188	usher protein
OIO78_00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OIO78_00305	COG2116	formate transmembrane transporter activity
OIO78_00325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO78_00330	COG1335	isochorismatase
OIO78_00335	COG0385	Bile acid
OIO78_00340	COG0534	Mate efflux family protein
OIO78_00345	COG1683	Conserved Protein
OIO78_00365	COG0625	glutathione transferase activity
OIO78_00375	COG1113	amino acid transport
OIO78_00385	COG0523	cobalamin synthesis protein
OIO78_00395	COG2188	Transcriptional regulator
OIO78_00425	COG0010	Belongs to the arginase family
OIO78_00445	COG1280	lysine exporter protein (LysE YggA)
OIO78_00470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIO78_00480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OIO78_00485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OIO78_00570	COG0534	Mate efflux family protein
OIO78_00575	COG0436	Aminotransferase
OIO78_00580	COG2733	membrane
OIO78_00595	COG2918	glutathione biosynthetic process
OIO78_00620	COG3150	esterase
OIO78_00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OIO78_00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO78_00650	COG2233	PERMEase
OIO78_00655	COG2351	hydroxyisourate hydrolase activity
OIO78_00690	COG3706	GGDEF domain
OIO78_00705	COG1393	Belongs to the ArsC family
OIO78_00710	COG0708	Exodeoxyribonuclease III
OIO78_00730	COG0189	ligase activity
OIO78_00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIO78_00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIO78_00775	COG4942	peptidase
OIO78_00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO78_00795	COG2119	membrane
OIO78_00800	COG4774	siderophore transport
OIO78_00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO78_00805	COG0426	domain, Protein
OIO78_00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OIO78_00855	COG1902	pentaerythritol trinitrate reductase activity
OIO78_00860	COG1519	Transferase
OIO78_00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO78_00870	COG0668	transmembrane transport
OIO78_00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO78_00885	COG1335	isochorismatase
OIO78_00890	COG1522	sequence-specific DNA binding
OIO78_00915	COG2198	Histidine kinase
OIO78_00915	COG2205	protein histidine kinase activity
OIO78_00915	COG0784	Response regulator, receiver
OIO78_00920	COG3162	membrane
OIO78_00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO78_00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO78_00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIO78_00960	COG1309	transcriptional regulator
OIO78_00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO78_00980	COG0352	thiamine-phosphate diphosphorylase activity
OIO78_00980	COG0351	phosphomethylpyrimidine kinase
OIO78_00990	COG2814	Major facilitator Superfamily
OIO78_01030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO78_01040	COG1113	amino acid transport
OIO78_01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO78_01055	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_01065	COG1335	isochorismatase
OIO78_01100	COG2814	Major facilitator Superfamily
OIO78_01105	COG0583	DNA-binding transcription factor activity
OIO78_01120	COG1309	transcriptional regulator
OIO78_01140	COG0667	Aldo Keto reductase
OIO78_01175	COG1733	regulation of RNA biosynthetic process
OIO78_01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO78_01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OIO78_01260	COG2329	Antibiotic biosynthesis monooxygenase
OIO78_01275	COG1132	(ABC) transporter
OIO78_01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIO78_01325	COG0427	acetyl-CoA hydrolase
OIO78_01350	COG0659	secondary active sulfate transmembrane transporter activity
OIO78_01355	COG4221	oxidoreductase activity
OIO78_01360	COG2873	o-acetylhomoserine
OIO78_01365	COG0488	(ABC) transporter
OIO78_01430	COG0833	amino acid
OIO78_01475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIO78_01480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIO78_01495	COG2226	methyltransferase
OIO78_01545	COG0070	glutamate synthase
OIO78_01545	COG0069	glutamate synthase activity
OIO78_01545	COG0067	glutamate synthase
OIO78_01550	COG0493	'glutamate synthase
OIO78_01560	COG1704	LemA family
OIO78_01565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OIO78_01580	COG3307	-O-antigen
OIO78_01600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO78_01615	COG0194	GDP metabolic process
OIO78_01670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIO78_01690	COG5380	lipid catabolic process
OIO78_01695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIO78_01720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIO78_01725	COG0277	FAD linked oxidase domain protein
OIO78_01735	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OIO78_01740	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO78_01755	COG1289	transmembrane transporter activity
OIO78_01765	COG0628	permease
OIO78_01770	COG1192	Involved in chromosome partitioning
OIO78_01800	COG0833	amino acid
OIO78_01805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO78_01810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO78_01820	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_01860	COG0583	DNA-binding transcription factor activity
OIO78_01885	COG0752	glycyl-tRNA synthetase alpha subunit
OIO78_01910	COG0517	IMP dehydrogenase activity
OIO78_01915	COG1983	PspC domain protein
OIO78_01925	COG1960	acyl-CoA dehydrogenase activity
OIO78_01940	COG0408	coproporphyrinogen oxidase activity
OIO78_01960	COG0513	Belongs to the DEAD box helicase family
OIO78_01970	COG1127	ABC transporter
OIO78_01975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIO78_01985	COG2854	intermembrane phospholipid transfer
OIO78_01995	COG0598	Magnesium transport protein CorA
OIO78_02005	COG0494	nUDIX hydrolase
OIO78_02010	COG1040	competence protein
OIO78_02015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIO78_02035	COG1946	Acyl-CoA thioesterase
OIO78_02040	COG1301	dicarboxylic acid transport
OIO78_02055	COG1959	2 iron, 2 sulfur cluster binding
OIO78_02060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO78_02060	COG1017	nitric oxide dioxygenase activity
OIO78_02225	COG1960	acyl-CoA dehydrogenase activity
OIO78_02230	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OIO78_02260	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OIO78_02265	COG0339	signal peptide processing
OIO78_02270	COG0557	exoribonuclease II activity
OIO78_02315	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO78_02320	COG2169	Transcriptional regulator
OIO78_02325	COG0697	spore germination
OIO78_02330	COG1295	ribonuclease BN
OIO78_02365	COG1702	phosphate starvation-inducible protein PhoH
OIO78_02375	COG0739	heme binding
OIO78_02375	COG0741	lytic transglycosylase activity
OIO78_02375	COG1196	nuclear chromosome segregation
OIO78_02405	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OIO78_02410	COG1183	phosphatidylcholine synthase activity
OIO78_02455	COG1960	acyl-CoA dehydrogenase activity
OIO78_02460	COG1309	transcriptional regulator
OIO78_02475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO78_02480	COG1960	acyl-CoA dehydrogenase activity
OIO78_02500	COG2969	positive regulation of protein catabolic process
OIO78_02510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIO78_02520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OIO78_02525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIO78_02530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIO78_02550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIO78_02560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO78_02565	COG1408	metallophosphoesterase
OIO78_02575	COG2199	diguanylate cyclase activity
OIO78_02635	COG1607	acyl-coa hydrolase
OIO78_02665	COG2350	Protein conserved in bacteria
OIO78_02675	COG0613	PHP domain protein
OIO78_02680	COG3781	membrane
OIO78_02690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIO78_02695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIO78_02705	COG1862	Preprotein translocase
OIO78_02735	COG2205	protein histidine kinase activity
OIO78_02740	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIO78_02760	COG0726	polysaccharide deacetylase
OIO78_02765	COG0463	Glycosyl transferase, family 2
OIO78_02770	COG0438	transferase activity, transferring glycosyl groups
OIO78_02835	COG1960	acyl-CoA dehydrogenase activity
OIO78_02840	COG1960	acyl-CoA dehydrogenase activity
OIO78_02850	COG2205	protein histidine kinase activity
OIO78_02855	COG0745	RESPONSE REGULATOR receiver
OIO78_02860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OIO78_02875	COG0584	glycerophosphoryl diester phosphodiesterase
OIO78_02880	COG2096	Adenosyltransferase
OIO78_02930	COG0285	dihydrofolate synthase activity
OIO78_02950	COG0450	alkyl hydroperoxide reductase
OIO78_02965	COG0477	Major facilitator Superfamily
OIO78_02970	COG1272	protein, Hemolysin III
OIO78_03000	COG0183	Belongs to the thiolase family
OIO78_03005	COG2207	Transcriptional regulator
OIO78_03025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO78_03045	COG0183	Belongs to the thiolase family
OIO78_03055	COG2885	chlorophyll binding
OIO78_03055	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OIO78_03065	COG1690	Belongs to the RtcB family
OIO78_03070	COG0833	amino acid
OIO78_03080	COG2233	PERMEase
OIO78_03085	COG1217	gtp-binding protein TYPA
OIO78_03110	COG2094	Belongs to the DNA glycosylase MPG family
OIO78_03115	COG4772	TonB-dependent receptor
OIO78_03120	COG1902	pentaerythritol trinitrate reductase activity
OIO78_03135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO78_03140	COG0354	folic acid binding
OIO78_03150	COG3189	MarR family transcriptional regulator
OIO78_03155	COG2824	Alkylphosphonate utilization operon protein PhnA
OIO78_03160	COG3422	double-strand break repair
OIO78_03200	COG0840	transmembrane signaling receptor activity
OIO78_03225	COG5510	response to toxic substance
OIO78_03235	COG2832	Protein of unknown function (DUF454)
OIO78_03240	COG1376	ErfK ybiS ycfS ynhG family protein
OIO78_03290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OIO78_03300	COG1289	transmembrane transporter activity
OIO78_03305	COG2814	Major facilitator Superfamily
OIO78_03325	COG1115	amino acid carrier protein
OIO78_03330	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO78_03335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO78_03340	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OIO78_03365	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO78_03375	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO78_03380	COG1077	Cell shape determining protein MreB Mrl
OIO78_03385	COG1792	Involved in formation and maintenance of cell shape
OIO78_03390	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OIO78_03395	COG0424	maF-like protein
OIO78_03400	COG1530	ribonuclease E activity
OIO78_03410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO78_03420	COG0560	Phosphoserine phosphatase
OIO78_03430	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO78_03455	COG2207	Transcriptional regulator
OIO78_03500	COG1113	amino acid transport
OIO78_03505	COG2828	Protein conserved in bacteria
OIO78_03510	COG0142	geranyltranstransferase activity
OIO78_03515	COG2315	Protein conserved in bacteria
OIO78_03530	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO78_03550	COG2194	sulfuric ester hydrolase activity
OIO78_03555	COG0745	RESPONSE REGULATOR receiver
OIO78_03560	COG0642	Histidine kinase
OIO78_03575	COG0004	ammonium transporteR
OIO78_03580	COG0583	DNA-binding transcription factor activity
OIO78_03600	COG0525	valine-tRNA ligase activity
OIO78_03610	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_03620	COG0393	Putative heavy-metal-binding
OIO78_03625	COG0393	Putative heavy-metal-binding
OIO78_03630	COG1538	Outer membrane efflux protein
OIO78_03640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO78_03675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OIO78_03690	COG1648	precorrin-2 dehydrogenase activity
OIO78_03690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIO78_03695	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIO78_03700	COG1733	regulation of RNA biosynthetic process
OIO78_03710	COG0531	amino acid
OIO78_03725	COG0321	lipoyl(octanoyl) transferase activity
OIO78_03730	COG2921	Belongs to the UPF0250 family
OIO78_03765	COG2009	succinate dehydrogenase
OIO78_03770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OIO78_03775	COG1053	succinate dehydrogenase
OIO78_03780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIO78_03805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO78_03825	COG2354	Protein conserved in bacteria
OIO78_03830	COG2321	neutral zinc metallopeptidase
OIO78_03850	COG2843	Capsule synthesis protein
OIO78_03865	COG0589	response to stress
OIO78_03885	COG0505	Belongs to the CarA family
OIO78_03910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO78_03915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIO78_03965	COG0477	Major facilitator Superfamily
OIO78_03970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIO78_03985	COG1597	lipid kinase activity
OIO78_03990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO78_04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO78_04020	COG0584	glycerophosphoryl diester phosphodiesterase
OIO78_04040	COG0741	lytic transglycosylase activity
OIO78_04060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIO78_04075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO78_04100	COG3811	Belongs to the UPF0386 family
OIO78_04125	COG0778	Nitroreductase
OIO78_04140	COG1929	Belongs to the glycerate kinase type-1 family
OIO78_04145	COG0243	molybdopterin cofactor binding
OIO78_04150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIO78_04155	COG3339	Conserved Protein
OIO78_04165	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OIO78_04180	COG1113	amino acid transport
OIO78_04190	COG0019	diaminopimelate decarboxylase activity
OIO78_04200	COG2267	carboxylic ester hydrolase activity
OIO78_04205	COG1280	lysine exporter protein (LysE YggA)
OIO78_04210	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO78_04240	COG0463	Glycosyl transferase, family 2
OIO78_04260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO78_04295	COG4591	ABC-type transport system involved in lipoprotein release permease component
OIO78_04300	COG1136	(ABC) transporter
OIO78_04305	COG0658	competence protein
OIO78_04305	COG2333	competence protein COMEC
OIO78_04315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIO78_04315	COG0616	signal peptide processing
OIO78_04320	COG0596	Alpha beta hydrolase
OIO78_04325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIO78_04335	COG0628	permease
OIO78_04370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO78_04390	COG0823	Involved in the tonB-independent uptake of proteins
OIO78_04410	COG0824	Thioesterase
OIO78_04415	COG1473	amidohydrolase
OIO78_04435	COG0047	phosphoribosylformylglycinamidine synthase activity
OIO78_04435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIO78_04440	COG2814	Major facilitator Superfamily
OIO78_04455	COG1024	Enoyl-CoA hydratase
OIO78_04460	COG1051	belongs to the nudix hydrolase family
OIO78_04460	COG1056	cytidyltransferase-related domain
OIO78_04470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OIO78_04485	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OIO78_04500	COG4625	pathogenesis
OIO78_04505	COG0583	DNA-binding transcription factor activity
OIO78_04510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OIO78_04515	COG4208	sulfate ABC transporter
OIO78_04520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIO78_04530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OIO78_04535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIO78_04540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIO78_04560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO78_04570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIO78_04580	COG0681	Belongs to the peptidase S26 family
OIO78_04595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIO78_04605	COG1381	Involved in DNA repair and RecF pathway recombination
OIO78_04610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OIO78_04620	COG4221	oxidoreductase activity
OIO78_04650	COG0443	Heat shock 70 kDa protein
OIO78_04660	COG0436	Aminotransferase
OIO78_04680	COG0556	nucleotide-excision repair
OIO78_04735	COG2070	2-Nitropropane dioxygenase
OIO78_04750	COG1252	NADH dehydrogenase
OIO78_04755	COG1686	Belongs to the peptidase S11 family
OIO78_04770	COG1187	pseudouridine synthase activity
OIO78_04965	COG4695	Portal protein
OIO78_05100	COG0582	viral genome integration into host DNA
OIO78_05125	COG0477	Major facilitator Superfamily
OIO78_05130	COG0583	DNA-binding transcription factor activity
OIO78_05135	COG1823	symporter activity
OIO78_05145	COG0612	Peptidase, M16
OIO78_05170	COG0352	thiamine-phosphate diphosphorylase activity
OIO78_05205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO78_05220	COG1309	transcriptional regulator
OIO78_05230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO78_05235	COG0076	glutamate decarboxylase activity
OIO78_05245	COG1522	sequence-specific DNA binding
OIO78_05250	COG3961	Belongs to the TPP enzyme family
OIO78_05255	COG1113	amino acid transport
OIO78_05260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIO78_05265	COG0573	inorganic phosphate transmembrane transporter activity
OIO78_05275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIO78_05280	COG0616	signal peptide processing
OIO78_05315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OIO78_05320	COG1686	Belongs to the peptidase S11 family
OIO78_05345	COG0583	DNA-binding transcription factor activity
OIO78_05350	COG1067	ATP-dependent peptidase activity
OIO78_05375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OIO78_05395	COG1966	Carbon starvation protein
OIO78_05400	COG2879	small protein
OIO78_05440	COG1335	isochorismatase
OIO78_05445	COG0583	DNA-binding transcription factor activity
OIO78_05460	COG0596	Alpha beta hydrolase
OIO78_05470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO78_05480	COG2130	NADP-dependent
OIO78_05510	COG1741	Belongs to the pirin family
OIO78_05520	COG2964	Protein conserved in bacteria
OIO78_05535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO78_05545	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO78_05550	COG4605	iron ion homeostasis
OIO78_05555	COG4604	ABC transporter, ATP-binding protein
OIO78_05560	COG4607	ABC-type enterochelin transport system periplasmic component
OIO78_05565	COG4774	siderophore transport
OIO78_05575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO78_05580	COG1021	2,3-dihydroxybenzoate-AMP ligase
OIO78_05585	COG3433	isochorismatase activity
OIO78_05585	COG1535	isochorismatase
OIO78_05600	COG1132	(ABC) transporter
OIO78_05605	COG1132	(ABC) transporter
OIO78_05610	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OIO78_05615	COG2977	Belongs to the P-Pant transferase superfamily
OIO78_05635	COG3739	integral membrane protein
OIO78_05655	COG0302	gtp cyclohydrolase
OIO78_05665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIO78_05695	COG0308	aminopeptidase N
OIO78_05700	COG0512	Glutamine amidotransferase of anthranilate synthase
OIO78_05715	COG0174	glutamine synthetase
OIO78_05725	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OIO78_05760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIO78_05765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIO78_05770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO78_05790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO78_05795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIO78_05800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIO78_05815	COG1960	acyl-CoA dehydrogenase activity
OIO78_05820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO78_05825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO78_05835	COG2223	nitrite transmembrane transporter activity
OIO78_05855	COG0024	Methionine aminopeptidase
OIO78_05860	COG0052	Belongs to the universal ribosomal protein uS2 family
OIO78_05875	COG2207	Transcriptional regulator
OIO78_05900	COG2951	lytic endotransglycosylase activity
OIO78_05905	COG0772	Belongs to the SEDS family
OIO78_05920	COG0842	Transport permease protein
OIO78_05925	COG1131	(ABC) transporter
OIO78_05970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO78_05985	COG4215	(ABC) transporter
OIO78_05990	COG4160	amino acid transport
OIO78_05995	COG4598	ABC transporter
OIO78_06005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO78_06010	COG0826	peptidase U32
OIO78_06015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO78_06030	COG1720	tRNA m6t6A37 methyltransferase activity
OIO78_06040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OIO78_06055	COG0642	Histidine kinase
OIO78_06065	COG0494	nUDIX hydrolase
OIO78_06075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIO78_06080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIO78_06085	COG3139	Protein of unknown function (DUF1315)
OIO78_06095	COG1301	dicarboxylic acid transport
OIO78_06100	COG1960	acyl-CoA dehydrogenase activity
OIO78_06105	COG2819	hydrolase of the alpha beta superfamily
OIO78_06115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIO78_06125	COG2195	Cleaves the N-terminal amino acid of tripeptides
OIO78_06145	COG1690	Belongs to the RtcB family
OIO78_06150	COG1234	tRNA 3'-trailer cleavage
OIO78_06155	COG4650	regulator
OIO78_06185	COG2363	Small membrane protein
OIO78_06210	COG0513	Belongs to the DEAD box helicase family
OIO78_06220	COG0778	Nitroreductase
OIO78_06250	COG1286	toxin biosynthetic process
OIO78_06275	COG4783	chaperone-mediated protein folding
OIO78_06280	COG1610	YqeY-like protein
OIO78_06310	COG0515	serine threonine protein kinase
OIO78_06310	COG2815	serine threonine protein kinase
OIO78_06380	COG3111	PFAM Bacterial OB fold (BOF) protein
OIO78_06405	COG3243	poly(R)-hydroxyalkanoic acid synthase
OIO78_06410	COG0786	glutamate:sodium symporter activity
OIO78_06420	COG2186	Transcriptional regulator
OIO78_06430	COG0477	Major facilitator Superfamily
OIO78_06460	COG2995	paraquat-inducible protein a
OIO78_06465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIO78_06465	COG3008	intermembrane lipid transfer
OIO78_06475	COG1794	racemase activity, acting on amino acids and derivatives
OIO78_06505	COG1301	dicarboxylic acid transport
OIO78_06520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO78_06525	COG2011	ABC-type metal ion transport system permease component
OIO78_06530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO78_06535	COG1464	Belongs to the NlpA lipoprotein family
OIO78_06540	COG0151	Belongs to the GarS family
OIO78_06545	COG0138	bifunctional purine biosynthesis protein purh
OIO78_06550	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OIO78_06580	COG2308	Evidence 4 Homologs of previously reported genes of
OIO78_06590	COG1305	Transglutaminase-like
OIO78_06600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIO78_06605	COG0305	Participates in initiation and elongation during chromosome replication
OIO78_06630	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OIO78_06640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIO78_06645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIO78_06670	COG0726	polysaccharide deacetylase
OIO78_06670	COG1649	PFAM Uncharacterised BCR, COG1649
OIO78_06675	COG1215	transferase activity, transferring glycosyl groups
OIO78_06680	COG3658	cytochrome
OIO78_06690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO78_06705	COG0583	DNA-binding transcription factor activity
OIO78_06725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO78_06730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO78_06745	COG1960	acyl-CoA dehydrogenase activity
OIO78_06750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO78_06755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO78_06770	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OIO78_06780	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIO78_06785	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIO78_06800	COG0745	RESPONSE REGULATOR receiver
OIO78_06805	COG0174	glutamine synthetase
OIO78_06825	COG0729	surface antigen
OIO78_06850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO78_06855	COG2814	Major facilitator Superfamily
OIO78_06870	COG0583	DNA-binding transcription factor activity
OIO78_06885	COG1187	pseudouridine synthase activity
OIO78_06905	COG0802	atpase or kinase
OIO78_06910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIO78_06920	COG1923	regulation of RNA biosynthetic process
OIO78_06925	COG0697	spore germination
OIO78_06950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO78_06955	COG0519	Catalyzes the synthesis of GMP from XMP
OIO78_06955	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO78_06960	COG4302	ethanolamine ammonia-lyase activity
OIO78_06965	COG4303	Ethanolamine ammonia lyase large subunit
OIO78_06970	COG0531	amino acid
OIO78_06990	COG1454	alcohol dehydrogenase
OIO78_06995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO78_07005	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OIO78_07025	COG0308	aminopeptidase N
OIO78_07045	COG1605	Chorismate mutase
OIO78_07065	COG1309	transcriptional regulator
OIO78_07075	COG0668	transmembrane transport
OIO78_07105	COG4773	Receptor
OIO78_07125	COG0488	(ABC) transporter
OIO78_07130	COG0589	response to stress
OIO78_07155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIO78_07165	COG3135	benzoate transporter
OIO78_07170	COG1522	sequence-specific DNA binding
OIO78_07180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIO78_07185	COG0583	DNA-binding transcription factor activity
OIO78_07195	COG0183	Belongs to the thiolase family
OIO78_07205	COG2030	dehydratase
OIO78_07210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO78_07225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIO78_07240	COG0824	Thioesterase
OIO78_07245	COG1454	alcohol dehydrogenase
OIO78_07255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIO78_07275	COG0069	glutamate synthase activity
OIO78_07295	COG2814	Major facilitator Superfamily
OIO78_07310	COG0511	ligase activity, forming carbon-carbon bonds
OIO78_07330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO78_07330	COG1116	anion transmembrane transporter activity
OIO78_07335	COG0745	RESPONSE REGULATOR receiver
OIO78_07345	COG2146	nitrite reductase [NAD(P)H] activity
OIO78_07345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO78_07350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO78_07355	COG0243	molybdopterin cofactor binding
OIO78_07365	COG0243	molybdopterin cofactor binding
OIO78_07385	COG0315	cyclic pyranopterin monophosphate synthase activity
OIO78_07385	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIO78_07400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO78_07405	COG0697	spore germination
OIO78_07425	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OIO78_07430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO78_07485	COG2204	response regulator
OIO78_07490	COG3852	Histidine kinase
OIO78_07510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIO78_07515	COG0575	Belongs to the CDS family
OIO78_07530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO78_07550	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO78_07565	COG2137	regulation of response to DNA damage stimulus
OIO78_07575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OIO78_07580	COG1011	Hydrolase
OIO78_07605	COG1522	sequence-specific DNA binding
OIO78_07615	COG1113	amino acid transport
OIO78_07635	COG0659	secondary active sulfate transmembrane transporter activity
OIO78_07640	COG2135	peptidase activity
OIO78_07655	COG3300	MHYT domain
OIO78_07655	COG5001	Diguanylate cyclase
OIO78_07675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO78_07675	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIO78_07675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO78_07680	COG1105	Belongs to the carbohydrate kinase PfkB family
OIO78_07685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIO78_07685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO78_07715	COG0024	Methionine aminopeptidase
OIO78_07720	COG0583	DNA-binding transcription factor activity
OIO78_07730	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OIO78_07735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO78_07740	COG0516	GMP reductase activity
OIO78_07740	COG0517	IMP dehydrogenase activity
OIO78_07765	COG0552	protein localization to endoplasmic reticulum
OIO78_07775	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OIO78_07785	COG4890	Cyd operon protein YbgT
OIO78_07790	COG1294	oxidase, subunit
OIO78_07805	COG1585	Membrane protein implicated in regulation of membrane protease activity
OIO78_07815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIO78_07820	COG4774	siderophore transport
OIO78_07835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIO78_07840	COG0569	domain protein
OIO78_07845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO78_07875	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIO78_07880	COG0542	response to heat
OIO78_07890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO78_07905	COG1902	pentaerythritol trinitrate reductase activity
OIO78_07905	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO78_07950	COG2323	membrane
OIO78_07955	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OIO78_07965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO78_07970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO78_07975	COG0183	Belongs to the thiolase family
OIO78_07980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIO78_07985	COG0596	Alpha beta hydrolase
OIO78_07990	COG2271	Major facilitator Superfamily
OIO78_07995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO78_08000	COG3485	protocatechuate 3,4-dioxygenase
OIO78_08005	COG3485	protocatechuate 3,4-dioxygenase
OIO78_08010	COG0710	3-dehydroquinate dehydratase activity
OIO78_08015	COG3420	alginic acid biosynthetic process
OIO78_08020	COG3659	wide pore channel activity
OIO78_08025	COG4993	Dehydrogenase
OIO78_08035	COG2391	methyltransferase activity
OIO78_08050	COG1414	Transcriptional regulator
OIO78_08055	COG0583	DNA-binding transcription factor activity
OIO78_08060	COG1960	acyl-CoA dehydrogenase activity
OIO78_08085	COG2814	Major facilitator Superfamily
OIO78_08095	COG0154	amidase activity
OIO78_08115	COG4638	Rieske (2fe-2S)
OIO78_08125	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_08135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO78_08145	COG3733	amine oxidase
OIO78_08155	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_08165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO78_08170	COG0183	Belongs to the thiolase family
OIO78_08175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO78_08180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO78_08190	COG4829	muconolactone delta-isomerase
OIO78_08195	COG4948	Mandelate Racemase Muconate Lactonizing
OIO78_08200	COG0583	DNA-binding transcription factor activity
OIO78_08210	COG2186	Transcriptional regulator
OIO78_08230	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_08235	COG3231	kanamycin kinase activity
OIO78_08250	COG1960	acyl-CoA dehydrogenase activity
OIO78_08255	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_08260	COG3829	transcription factor binding
OIO78_08270	COG3162	membrane
OIO78_08285	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_08300	COG0753	catalase activity
OIO78_08325	COG1846	Transcriptional regulator
OIO78_08330	COG1902	pentaerythritol trinitrate reductase activity
OIO78_08330	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO78_08365	COG1309	transcriptional regulator
OIO78_08375	COG1335	isochorismatase
OIO78_08380	COG0583	DNA-binding transcription factor activity
OIO78_08390	COG0475	glutathione-regulated potassium exporter activity
OIO78_08390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO78_08400	COG1473	amidohydrolase
OIO78_08455	COG2188	Transcriptional regulator
OIO78_08470	COG0583	DNA-binding transcription factor activity
OIO78_08505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO78_08525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO78_08545	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_08560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO78_08565	COG2814	Major facilitator Superfamily
OIO78_08575	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO78_08585	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_08590	COG3384	dioxygenase
OIO78_08600	COG3971	2-oxopent-4-enoate hydratase activity
OIO78_08615	COG0477	Major facilitator Superfamily
OIO78_08620	COG1960	acyl-CoA dehydrogenase activity
OIO78_08625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO78_08630	COG1846	Transcriptional regulator
OIO78_08635	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_08640	COG0129	dihydroxy-acid dehydratase activity
OIO78_08650	COG0583	DNA-binding transcription factor activity
OIO78_08655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO78_08665	COG2084	Dehydrogenase
OIO78_08670	COG2207	Transcriptional regulator
OIO78_08685	COG1064	alcohol dehydrogenase
OIO78_08695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO78_08700	COG1120	ATPase activity
OIO78_08720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO78_08770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OIO78_08795	COG2814	Major facilitator Superfamily
OIO78_08800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO78_08800	COG3320	Male sterility
OIO78_08830	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_08840	COG2207	Transcriptional regulator
OIO78_08850	COG2205	protein histidine kinase activity
OIO78_08855	COG0745	RESPONSE REGULATOR receiver
OIO78_08860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO78_08865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO78_08890	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO78_08900	COG0753	catalase activity
OIO78_08920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO78_08980	COG1535	isochorismatase
OIO78_08980	COG3433	isochorismatase activity
OIO78_08985	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_08990	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OIO78_08995	COG4149	molybdate abc transporter
OIO78_09000	COG0725	ABC transporter, periplasmic molybdate-binding protein
OIO78_09010	COG4638	Rieske (2fe-2S)
OIO78_09015	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO78_09020	COG0543	2 iron, 2 sulfur cluster binding
OIO78_09020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO78_09035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO78_09045	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_09060	COG2207	Transcriptional regulator
OIO78_09065	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_09070	COG2610	gluconate transmembrane transporter activity
OIO78_09080	COG0583	DNA-binding transcription factor activity
OIO78_09095	COG2031	fatty acid transporter
OIO78_09100	COG0183	Belongs to the thiolase family
OIO78_09105	COG0583	DNA-binding transcription factor activity
OIO78_09110	COG0583	DNA-binding transcription factor activity
OIO78_09125	COG1027	Aspartate ammonia-lyase
OIO78_09135	COG0477	Major facilitator Superfamily
OIO78_09155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO78_09160	COG4521	taurine ABC transporter
OIO78_09175	COG2188	Transcriptional regulator
OIO78_09185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIO78_09190	COG1733	regulation of RNA biosynthetic process
OIO78_09195	COG2207	Transcriptional regulator
OIO78_09195	COG3708	Transcriptional regulator
OIO78_09210	COG0730	response to heat
OIO78_09225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO78_09225	COG3453	Protein conserved in bacteria
OIO78_09235	COG3781	membrane
OIO78_09240	COG1063	alcohol dehydrogenase
OIO78_09250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO78_09255	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO78_09260	COG0022	dehydrogenase e1 component
OIO78_09265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OIO78_09270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO78_09285	COG3706	GGDEF domain
OIO78_09300	COG0133	tryptophan synthase activity
OIO78_09310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO78_09345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIO78_09370	COG2226	methyltransferase
OIO78_09425	COG0842	Transport permease protein
OIO78_09430	COG0842	Transport permease protein
OIO78_09435	COG1131	(ABC) transporter
OIO78_09450	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO78_09475	COG0730	response to heat
OIO78_09480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO78_09495	COG0406	alpha-ribazole phosphatase activity
OIO78_09500	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIO78_09515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO78_09545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO78_09555	COG4264	IucA IucC family
OIO78_09560	COG4264	IucA IucC family
OIO78_09565	COG2814	Major facilitator Superfamily
OIO78_09580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIO78_09595	COG1960	acyl-CoA dehydrogenase activity
OIO78_09600	COG1960	acyl-CoA dehydrogenase activity
OIO78_09605	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO78_09610	COG2207	Transcriptional regulator
OIO78_09615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO78_09620	COG0776	regulation of translation
OIO78_09645	COG0822	iron-sulfur transferase activity
OIO78_09650	COG0316	Belongs to the HesB IscA family
OIO78_09680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO78_09700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO78_09705	COG0702	epimerase
OIO78_09740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIO78_09750	COG0339	signal peptide processing
OIO78_09760	COG4166	transmembrane transport
OIO78_09795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIO78_09800	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OIO78_09830	COG0776	regulation of translation
OIO78_09895	COG0084	hydrolase, TatD family'
OIO78_09915	COG1663	tetraacyldisaccharide 4'-kinase activity
OIO78_09920	COG1132	(ABC) transporter
OIO78_09930	COG0811	peptide transport
OIO78_09935	COG1475	DNA binding
OIO78_09940	COG1192	Involved in chromosome partitioning
OIO78_09950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIO78_09965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO78_09970	COG0191	fructose-bisphosphate aldolase activity
OIO78_09990	COG0424	maF-like protein
OIO78_09995	COG2850	peptidyl-arginine hydroxylation
OIO78_10005	COG0640	Transcriptional regulator
OIO78_10015	COG3619	membrane
OIO78_10020	COG3122	Protein conserved in bacteria
OIO78_10025	COG1132	(ABC) transporter
OIO78_10045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIO78_10050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO78_10060	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO78_10060	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO78_10060	COG0506	proline dehydrogenase activity
OIO78_10065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIO78_10080	COG3698	Phosphodiester glycosidase
OIO78_10090	COG2353	YceI-like domain
OIO78_10100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIO78_10145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIO78_10145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIO78_10170	COG3539	Fimbrial protein
OIO78_10175	COG3121	Chaperone
OIO78_10200	COG0697	spore germination
OIO78_10210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO78_10220	COG0583	DNA-binding transcription factor activity
OIO78_10240	COG1309	transcriptional regulator
OIO78_10255	COG1522	sequence-specific DNA binding
OIO78_10265	COG1126	abc transporter atp-binding protein
OIO78_10270	COG0765	amino acid transport
OIO78_10275	COG0765	amino acid transport
OIO78_10305	COG1464	Belongs to the NlpA lipoprotein family
OIO78_10315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO78_10320	COG2011	ABC-type metal ion transport system permease component
OIO78_10325	COG0012	GTP binding
OIO78_10350	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO78_10390	COG0386	Belongs to the glutathione peroxidase family
OIO78_10400	COG0436	Aminotransferase
OIO78_10405	COG1301	dicarboxylic acid transport
OIO78_10440	COG3634	alkyl hydroperoxide reductase activity
OIO78_10455	COG0583	DNA-binding transcription factor activity
OIO78_10460	COG0798	PFAM Bile acid sodium symporter
OIO78_10465	COG0640	Transcriptional regulator
OIO78_10480	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIO78_10490	COG0583	DNA-binding transcription factor activity
OIO78_10500	COG1953	Uracil, thiamine, allantoin
OIO78_10510	COG2175	clavaminate synthase activity
OIO78_10515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO78_10535	COG4521	taurine ABC transporter
OIO78_10545	COG0477	Major facilitator Superfamily
OIO78_10565	COG1271	oxidase subunit
OIO78_10570	COG1294	oxidase, subunit
OIO78_10580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO78_10600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OIO78_10620	COG3052	prosthetic group binding
OIO78_10625	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OIO78_10635	COG0583	DNA-binding transcription factor activity
OIO78_10645	COG2814	Major facilitator Superfamily
OIO78_10665	COG1346	cytolysis
OIO78_10675	COG0583	DNA-binding transcription factor activity
OIO78_10680	COG0625	glutathione transferase activity
OIO78_10685	COG0625	glutathione transferase activity
OIO78_10690	COG0583	DNA-binding transcription factor activity
OIO78_10695	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_10705	COG1045	serine acetyltransferase
OIO78_10710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO78_10715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIO78_10725	COG1280	lysine exporter protein (LysE YggA)
OIO78_10740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO78_10745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO78_10750	COG1126	abc transporter atp-binding protein
OIO78_10755	COG0765	amino acid transport
OIO78_10760	COG0765	amino acid transport
OIO78_10780	COG2205	protein histidine kinase activity
OIO78_10780	COG0784	Response regulator, receiver
OIO78_10800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIO78_10820	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_10870	COG0583	DNA-binding transcription factor activity
OIO78_10890	COG0318	PFAM AMP-dependent synthetase and ligase
OIO78_10895	COG1309	transcriptional regulator
OIO78_10900	COG1960	acyl-CoA dehydrogenase activity
OIO78_10905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO78_10910	COG1024	Enoyl-CoA hydratase
OIO78_10915	COG4770	biotin carboxylase activity
OIO78_10925	COG0583	DNA-binding transcription factor activity
OIO78_10945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO78_10965	COG3842	ATPase activity
OIO78_10970	COG1840	ABC-type Fe3 transport system, periplasmic component
OIO78_10985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO78_10990	COG1414	Transcriptional regulator
OIO78_11000	COG0583	DNA-binding transcription factor activity
OIO78_11005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO78_11010	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_11020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO78_11030	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_11035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO78_11040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO78_11045	COG2267	carboxylic ester hydrolase activity
OIO78_11065	COG3038	cytochrome b561
OIO78_11070	COG0753	catalase activity
OIO78_11075	COG2271	Major facilitator Superfamily
OIO78_11080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO78_11085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO78_11125	COG2207	Transcriptional regulator
OIO78_11135	COG1278	Cold shock
OIO78_11170	COG0556	nucleotide-excision repair
OIO78_11180	COG2050	protein possibly involved in aromatic compounds catabolism
OIO78_11190	COG3327	negative regulation of DNA-templated transcription, initiation
OIO78_11195	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OIO78_11200	COG0183	Belongs to the thiolase family
OIO78_11205	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO78_11210	COG1024	Enoyl-CoA hydratase
OIO78_11215	COG1024	Enoyl-CoA hydratase
OIO78_11220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO78_11225	COG2151	metal-sulfur cluster biosynthetic enzyme
OIO78_11230	COG3396	Phenylacetate-CoA oxygenase
OIO78_11235	COG3460	Phenylacetate-CoA oxygenase
OIO78_11240	COG3396	Phenylacetate-CoA oxygenase
OIO78_11245	COG2030	dehydratase
OIO78_11245	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_11250	COG1760	l-serine dehydratase
OIO78_11255	COG0531	amino acid
OIO78_11260	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_11285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO78_11305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO78_11315	COG0789	Transcriptional regulator
OIO78_11325	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OIO78_11340	COG2807	transmembrane transport
OIO78_11345	COG0590	tRNA wobble adenosine to inosine editing
OIO78_11475	COG1116	anion transmembrane transporter activity
OIO78_11480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO78_11490	COG0864	Transcriptional regulator
OIO78_11500	COG1733	regulation of RNA biosynthetic process
OIO78_11505	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO78_11510	COG0439	Biotin carboxylase
OIO78_11525	COG1063	alcohol dehydrogenase
OIO78_11535	COG1309	transcriptional regulator
OIO78_11575	COG0038	chloride channel
OIO78_11580	COG4770	biotin carboxylase activity
OIO78_11600	COG1914	H( )-stimulated, divalent metal cation uptake system
OIO78_11660	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO78_11685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO78_11690	COG1116	anion transmembrane transporter activity
OIO78_11695	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO78_11725	COG0598	Magnesium transport protein CorA
OIO78_11735	COG1560	Kdo2-lipid A biosynthetic process
OIO78_11745	COG5006	permease, DMT superfamily
OIO78_11750	COG1522	sequence-specific DNA binding
OIO78_11765	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OIO78_11775	COG4122	O-methyltransferase activity
OIO78_11810	COG1137	ATPase activity
OIO78_11815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OIO78_11825	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OIO78_11830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OIO78_11830	COG0517	IMP dehydrogenase activity
OIO78_11870	COG2814	Major facilitator Superfamily
OIO78_11905	COG1278	Cold shock
OIO78_11910	COG1280	lysine exporter protein (LysE YggA)
OIO78_11940	COG1570	exodeoxyribonuclease VII activity
OIO78_11990	COG0583	DNA-binding transcription factor activity
OIO78_12000	COG4638	Rieske (2fe-2S)
OIO78_12010	COG0543	2 iron, 2 sulfur cluster binding
OIO78_12010	COG0633	Ferredoxin
OIO78_12015	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_12020	COG3135	benzoate transporter
OIO78_12025	COG2814	Major facilitator Superfamily
OIO78_12040	COG1643	Atp-dependent helicase
OIO78_12045	COG0450	alkyl hydroperoxide reductase
OIO78_12055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIO78_12065	COG3634	alkyl hydroperoxide reductase activity
OIO78_12085	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIO78_12240	COG0625	glutathione transferase activity
OIO78_12250	COG2885	chlorophyll binding
OIO78_12285	COG0542	response to heat
OIO78_12300	COG1765	OsmC-like protein
OIO78_12315	COG0667	Aldo Keto reductase
OIO78_12330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIO78_12345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIO78_12355	COG0527	aspartate kinase activity
OIO78_12365	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIO78_12375	COG3038	cytochrome b561
OIO78_12380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIO78_12385	COG2252	PERMEase
OIO78_12395	COG2072	flavoprotein involved in K transport
OIO78_12410	COG1741	Belongs to the pirin family
OIO78_12415	COG1309	transcriptional regulator
OIO78_12425	COG0300	oxidoreductase activity
OIO78_12430	COG2072	flavoprotein involved in K transport
OIO78_12435	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIO78_12480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO78_12500	COG2814	Major facilitator Superfamily
OIO78_12505	COG1024	Enoyl-CoA hydratase
OIO78_12510	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_12520	COG1960	acyl-CoA dehydrogenase activity
OIO78_12545	COG2186	Transcriptional regulator
OIO78_12550	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_12560	COG4948	Mandelate Racemase Muconate Lactonizing
OIO78_12565	COG2271	Major facilitator Superfamily
OIO78_12570	COG2721	sulfolactate sulfo-lyase activity
OIO78_12575	COG0697	spore germination
OIO78_12620	COG1113	amino acid transport
OIO78_12640	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_12660	COG0531	amino acid
OIO78_12670	COG1113	amino acid transport
OIO78_12710	COG3209	COG3209 Rhs family protein
OIO78_12730	COG4269	membrane
OIO78_12745	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO78_12745	COG1902	pentaerythritol trinitrate reductase activity
OIO78_12755	COG4251	negative regulation of phosphorylation
OIO78_12755	COG5001	Diguanylate cyclase
OIO78_12755	COG2203	Gaf domain
OIO78_12755	COG3706	GGDEF domain
OIO78_12765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO78_12790	COG4172	Belongs to the ABC transporter superfamily
OIO78_12795	COG4239	(ABC) transporter, permease
OIO78_12800	COG4174	ABC transporter (Permease)
OIO78_12810	COG0741	lytic transglycosylase activity
OIO78_12810	COG1388	LysM domain
OIO78_12810	COG0741	lytic transglycosylase activity
OIO78_12810	COG1388	LysM domain
OIO78_12815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO78_12855	COG0583	DNA-binding transcription factor activity
OIO78_12860	COG1279	arginine transmembrane transporter activity
OIO78_12880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO78_12885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO78_12890	COG0006	proline dipeptidase activity
OIO78_12925	COG2194	sulfuric ester hydrolase activity
OIO78_13090	COG5410	chromosome segregation
OIO78_13270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIO78_13290	COG3384	dioxygenase
OIO78_13300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO78_13305	COG2878	Part of a membrane complex involved in electron transport
OIO78_13310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIO78_13335	COG0768	penicillin binding
OIO78_13340	COG0742	ribosomal rna small subunit methyltransferase
OIO78_13355	COG0830	nickel cation binding
OIO78_13365	COG0804	urea catabolic process
OIO78_13405	COG1253	flavin adenine dinucleotide binding
OIO78_13410	COG2851	Citrate transporter
OIO78_13460	COG1773	rubredoxin
OIO78_13465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO78_13475	COG0583	DNA-binding transcription factor activity
OIO78_13505	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OIO78_13510	COG4181	ATPase activity
OIO78_13560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIO78_13585	COG0306	phosphate transporter
OIO78_13595	COG3958	Transketolase
OIO78_13600	COG3959	Transketolase, thiamine diphosphate binding domain
OIO78_13605	COG2271	Major facilitator Superfamily
OIO78_13610	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_13615	COG0583	DNA-binding transcription factor activity
OIO78_13635	COG2207	Transcriptional regulator
OIO78_13640	COG2066	Belongs to the glutaminase family
OIO78_13645	COG0242	peptide deformylase activity
OIO78_13650	COG0477	Major facilitator Superfamily
OIO78_13660	COG0028	Belongs to the TPP enzyme family
OIO78_13675	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_13680	COG2267	carboxylic ester hydrolase activity
OIO78_13690	COG2271	Major facilitator Superfamily
OIO78_13695	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO78_13705	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_13725	COG1414	Transcriptional regulator
OIO78_13740	COG1024	Enoyl-CoA hydratase
OIO78_13750	COG1215	transferase activity, transferring glycosyl groups
OIO78_13755	COG0726	polysaccharide deacetylase
OIO78_13755	COG1649	PFAM Uncharacterised BCR, COG1649
OIO78_13765	COG4681	YaeQ
OIO78_13775	COG0523	cobalamin synthesis protein
OIO78_13785	COG1607	acyl-coa hydrolase
OIO78_13795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO78_13800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO78_13805	COG1309	transcriptional regulator
OIO78_13830	COG2040	homocysteine
OIO78_13835	COG0531	amino acid
OIO78_13890	COG1595	DNA-templated transcription, initiation
OIO78_13900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO78_13905	COG0477	Major facilitator Superfamily
OIO78_13915	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OIO78_13975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO78_14060	COG0592	DNA-directed DNA polymerase activity
OIO78_14100	COG2026	Addiction module toxin, RelE StbE family
OIO78_14320	COG1484	DNA-dependent DNA replication
OIO78_14405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO78_14485	COG0405	Gamma-glutamyltransferase
OIO78_14490	COG2814	Major facilitator Superfamily
OIO78_14500	COG2050	protein possibly involved in aromatic compounds catabolism
OIO78_14515	COG1090	epimerase
OIO78_14535	COG0420	3'-5' exonuclease activity
OIO78_14560	COG0735	belongs to the Fur family
OIO78_14565	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO78_14585	COG0121	glutamine amidotransferase
OIO78_14600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO78_14610	COG0210	DNA helicase
OIO78_14615	COG2885	chlorophyll binding
OIO78_14620	COG0204	Acyl-transferase
OIO78_14635	COG2894	cell division
OIO78_14650	COG1280	lysine exporter protein (LysE YggA)
OIO78_14655	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OIO78_14655	COG1674	ftsk spoiiie
OIO78_14660	COG0492	ferredoxin-NADP+ reductase activity
OIO78_14665	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OIO78_14675	COG0456	acetyltransferase
OIO78_14720	COG1981	membrane
OIO78_14735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO78_14735	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIO78_14755	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_14765	COG0657	acetylesterase activity
OIO78_14775	COG0473	3-isopropylmalate dehydrogenase activity
OIO78_14780	COG0583	DNA-binding transcription factor activity
OIO78_14810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO78_14835	COG0564	pseudouridine synthase activity
OIO78_14845	COG0358	DNA primase activity
OIO78_14860	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OIO78_14890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO78_14920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIO78_14930	COG0351	phosphomethylpyrimidine kinase
OIO78_14930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO78_14930	COG0352	thiamine-phosphate diphosphorylase activity
OIO78_14935	COG1652	LysM domain
OIO78_14960	COG1399	metal-binding, possibly nucleic acid-binding protein
OIO78_14965	COG3101	peptidyl-lysine hydroxylation
OIO78_14970	COG0009	L-threonylcarbamoyladenylate synthase
OIO78_14975	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIO78_14980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIO78_14995	COG4106	trans-aconitate 2-methyltransferase activity
OIO78_15010	COG0596	Alpha beta hydrolase
OIO78_15010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO78_15010	COG2226	methyltransferase
OIO78_15015	COG1877	trehalose-phosphatase activity
OIO78_15020	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OIO78_15025	COG2223	nitrite transmembrane transporter activity
OIO78_15045	COG1196	nuclear chromosome segregation
OIO78_15055	COG0730	response to heat
OIO78_15070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIO78_15080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO78_15130	COG0489	protein tyrosine kinase activity
OIO78_15140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO78_15140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO78_15170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO78_15175	COG2081	HI0933 family
OIO78_15185	COG0668	transmembrane transport
OIO78_15205	COG0583	DNA-binding transcription factor activity
OIO78_15230	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIO78_15235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO78_15265	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIO78_15305	COG0745	RESPONSE REGULATOR receiver
OIO78_15325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO78_15330	COG0697	spore germination
OIO78_15365	COG0477	Major facilitator Superfamily
OIO78_15375	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_15395	COG0384	phenazine biosynthesis protein PhzF
OIO78_15440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO78_15455	COG0583	DNA-binding transcription factor activity
OIO78_15465	COG0583	DNA-binding transcription factor activity
OIO78_15480	COG0583	DNA-binding transcription factor activity
OIO78_15485	COG1053	succinate dehydrogenase
OIO78_15495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO78_15500	COG2814	Major facilitator Superfamily
OIO78_15505	COG1960	acyl-CoA dehydrogenase activity
OIO78_15510	COG0583	DNA-binding transcription factor activity
OIO78_15515	COG1063	alcohol dehydrogenase
OIO78_15545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIO78_15550	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIO78_15555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO78_15575	COG2132	Multicopper oxidase
OIO78_15585	COG0561	phosphatase activity
OIO78_15590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIO78_15600	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO78_15615	COG1214	PFAM Peptidase M22, glycoprotease
OIO78_15685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIO78_15690	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIO78_15695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIO78_15755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO78_15765	COG1846	Transcriptional regulator
OIO78_15770	COG1764	response to oxidative stress
OIO78_15810	COG0037	tRNA processing
OIO78_15820	COG0248	Ppx GppA phosphatase
OIO78_15850	COG0072	phenylalanine-tRNA ligase activity
OIO78_15895	COG1238	metal cluster binding
OIO78_15900	COG0625	glutathione transferase activity
OIO78_15915	COG0318	PFAM AMP-dependent synthetase and ligase
OIO78_15920	COG3028	Belongs to the UPF0307 family
OIO78_15925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO78_15945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OIO78_15950	COG0617	tRNA 3'-terminal CCA addition
OIO78_15955	COG1555	photosystem II stabilization
OIO78_15960	COG3956	TIGRFAM MazG family protein
OIO78_15970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO78_15990	COG0784	Response regulator, receiver
OIO78_15990	COG5002	protein histidine kinase activity
OIO78_15990	COG2205	protein histidine kinase activity
OIO78_15995	COG1024	Enoyl-CoA hydratase
OIO78_16000	COG2084	Dehydrogenase
OIO78_16005	COG3622	Belongs to the hyi family
OIO78_16040	COG0697	spore germination
OIO78_16050	COG2814	Major facilitator Superfamily
OIO78_16060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO78_16130	COG4774	siderophore transport
OIO78_16145	COG1271	oxidase subunit
OIO78_16150	COG1294	oxidase, subunit
OIO78_16220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO78_16230	COG0583	DNA-binding transcription factor activity
OIO78_16240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OIO78_16250	COG0084	hydrolase, TatD family'
OIO78_16265	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIO78_16295	COG0440	acetolactate synthase activity
OIO78_16300	COG0028	Belongs to the TPP enzyme family
OIO78_16325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO78_16330	COG1136	(ABC) transporter
OIO78_16330	COG0577	efflux transmembrane transporter activity
OIO78_16335	COG1538	Outer membrane efflux protein
OIO78_16350	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIO78_16355	COG1162	GTPase activity
OIO78_16365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OIO78_16405	COG1426	Protein conserved in bacteria
OIO78_16440	COG0793	Belongs to the peptidase S41A family
OIO78_16455	COG2267	carboxylic ester hydrolase activity
OIO78_16465	COG1012	belongs to the aldehyde dehydrogenase family
OIO78_16470	COG3265	gluconokinase activity
OIO78_16480	COG0800	Aldolase
OIO78_16490	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIO78_16495	COG0280	phosphate acetyltransferase
OIO78_16495	COG0857	belongs to the CobB CobQ family
OIO78_16500	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO78_16500	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO78_16520	COG0740	serine-type endopeptidase activity
OIO78_16530	COG4774	siderophore transport
OIO78_16540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO78_16550	COG2813	Specifically methylates the guanine in position
OIO78_16550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO78_16650	COG0788	formyltetrahydrofolate deformylase activity
OIO78_16675	COG4651	solute:proton antiporter activity
OIO78_16675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO78_16695	COG0724	RNA recognition motif
OIO78_16700	COG0210	DNA helicase
OIO78_16725	COG1733	regulation of RNA biosynthetic process
OIO78_16735	COG2900	Belongs to the SlyX family
OIO78_16740	COG0488	(ABC) transporter
OIO78_16745	COG1280	lysine exporter protein (LysE YggA)
OIO78_16750	COG1560	Kdo2-lipid A biosynthetic process
OIO78_16760	COG1301	dicarboxylic acid transport
OIO78_16815	COG0473	3-isopropylmalate dehydrogenase activity
OIO78_16870	COG0583	DNA-binding transcription factor activity
OIO78_16880	COG0625	glutathione transferase activity
OIO78_16885	COG2378	regulation of single-species biofilm formation
OIO78_16890	COG0546	phosphoglycolate phosphatase activity
OIO78_16900	COG1530	ribonuclease E activity
OIO78_16905	COG0318	PFAM AMP-dependent synthetase and ligase
OIO78_16920	COG0583	DNA-binding transcription factor activity
OIO78_16925	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_16930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIO78_16940	COG0534	Mate efflux family protein
OIO78_16955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OIO78_16980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO78_16980	COG0493	'glutamate synthase
OIO78_16990	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OIO78_16995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO78_17010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO78_17020	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OIO78_17020	COG0644	oxidoreductase
OIO78_17030	COG0425	Belongs to the sulfur carrier protein TusA family
OIO78_17035	COG4535	Mg2 and Co2 transporter CorC
OIO78_17045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO78_17065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIO78_17070	COG0475	glutathione-regulated potassium exporter activity
OIO78_17070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO78_17085	COG0484	heat shock protein binding
OIO78_17090	COG0789	Transcriptional regulator
OIO78_17095	COG0598	Magnesium transport protein CorA
OIO78_17110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO78_17115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO78_17120	COG1074	ATP-dependent DNA helicase activity
OIO78_17125	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OIO78_17145	COG2226	methyltransferase
OIO78_17165	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIO78_17180	COG2111	Na H antiporter
OIO78_17180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO78_17185	COG1006	Multisubunit Na H antiporter MnhC subunit
OIO78_17190	COG0651	ATP synthesis coupled electron transport
OIO78_17195	COG1863	multisubunit Na H antiporter MnhE subunit
OIO78_17200	COG2212	antiporter activity
OIO78_17205	COG1320	monovalent cation:proton antiporter activity
OIO78_17220	COG0195	Participates in both transcription termination and antitermination
OIO78_17270	COG0237	dephospho-CoA kinase activity
OIO78_17280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO78_17295	COG0497	DNA recombination
OIO78_17305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIO78_17335	COG2169	Transcriptional regulator
OIO78_17335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO78_17340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIO78_17400	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIO78_17415	COG0326	Molecular chaperone. Has ATPase activity
OIO78_17430	COG2056	Na+-H+ antiporter family
OIO78_17530	COG0546	phosphoglycolate phosphatase activity
OIO78_17535	COG1716	ATPase activity
OIO78_17580	COG0181	hydroxymethylbilane synthase activity
OIO78_17590	COG3275	phosphorelay sensor kinase activity
OIO78_17610	COG1538	Outer membrane efflux protein
OIO78_17615	COG0697	spore germination
OIO78_17660	COG1061	Type III restriction enzyme res subunit
OIO78_17665	COG1002	Type II restriction enzyme, methylase subunits
OIO78_17675	COG0659	secondary active sulfate transmembrane transporter activity
OIO78_17680	COG0589	response to stress
OIO78_17725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO78_17730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OIO78_17735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO78_17740	COG0772	Belongs to the SEDS family
OIO78_17765	COG4974	Belongs to the 'phage' integrase family
OIO78_17770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO78_17780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIO78_17790	COG2197	response regulator
OIO78_17805	COG0793	Belongs to the peptidase S41A family
OIO78_17810	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIO78_17815	COG0795	lipopolysaccharide-transporting ATPase activity
OIO78_17855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO78_17855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO78_17865	COG0004	ammonium transporteR
OIO78_17870	COG0347	Belongs to the P(II) protein family
OIO78_17905	COG1061	Type III restriction enzyme res subunit
OIO78_17910	COG1002	Type II restriction enzyme, methylase subunits
OIO78_17925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIO78_17940	COG0318	PFAM AMP-dependent synthetase and ligase
OIO78_17950	COG0477	Major facilitator Superfamily
OIO78_17955	COG2860	membrane
OIO78_17965	COG1253	flavin adenine dinucleotide binding
OIO78_17975	COG0477	Major facilitator Superfamily
OIO78_17980	COG3757	hydrolase, family 25
OIO78_17985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO78_18035	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIO78_18045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIO78_18115	COG0758	DNA mediated transformation
OIO78_18125	COG0697	spore germination
OIO78_18130	COG1309	transcriptional regulator
OIO78_18145	COG0386	Belongs to the glutathione peroxidase family
OIO78_18210	COG1121	(ABC) transporter
OIO78_18215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIO78_18220	COG1280	lysine exporter protein (LysE YggA)
OIO78_18225	COG2837	iron assimilation
OIO78_18235	COG0281	malic enzyme
OIO78_18280	COG0519	Catalyzes the synthesis of GMP from XMP
OIO78_18280	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO78_18285	COG4399	Belongs to the UPF0754 family
OIO78_18290	COG2259	Doxx family
OIO78_18295	COG0586	Pfam SNARE associated Golgi protein
OIO78_18310	COG1192	Involved in chromosome partitioning
OIO78_18320	COG0271	Belongs to the BolA IbaG family
OIO78_18340	COG2267	carboxylic ester hydrolase activity
OIO78_18360	COG3321	synthase
OIO78_18360	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OIO78_18360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIO78_18360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO78_18365	COG1960	acyl-CoA dehydrogenase activity
OIO78_18375	COG2197	response regulator
OIO78_18385	COG3916	Acyl-homoserine-lactone synthase
OIO78_18390	COG0477	Major facilitator Superfamily
OIO78_18395	COG1024	Enoyl-CoA hydratase
OIO78_18400	COG1024	Enoyl-CoA hydratase
OIO78_18405	COG1960	acyl-CoA dehydrogenase activity
OIO78_18410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO78_18430	COG1113	amino acid transport
OIO78_18435	COG1113	amino acid transport
OIO78_18440	COG0251	oxidation-reduction process
OIO78_18480	COG0564	pseudouridine synthase activity
OIO78_18510	COG1051	belongs to the nudix hydrolase family
OIO78_18535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIO78_18550	COG1802	Transcriptional regulator
OIO78_18560	COG1448	Aminotransferase
OIO78_18565	COG0277	FAD linked oxidase domain protein
OIO78_18575	COG2186	Transcriptional regulator
OIO78_18585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO78_18590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO78_18605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIO78_18615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OIO78_18625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OIO78_18630	COG0438	transferase activity, transferring glycosyl groups
OIO78_18640	COG0438	transferase activity, transferring glycosyl groups
OIO78_18660	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OIO78_18690	COG0728	peptidoglycan biosynthetic process
OIO78_18695	COG3023	N-Acetylmuramoyl-L-alanine amidase
OIO78_18730	COG1017	nitric oxide dioxygenase activity
OIO78_18730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO78_18755	COG0546	phosphoglycolate phosphatase activity
OIO78_18760	COG1028	Short-chain dehydrogenase reductase Sdr
OIO78_18780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO78_18785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO78_18790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO78_18795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO78_18800	COG1116	anion transmembrane transporter activity
OIO78_18805	COG1309	transcriptional regulator
OIO78_18810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO78_18820	COG0196	riboflavin kinase activity
OIO78_18825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIO78_18835	COG1047	Peptidyl-prolyl cis-trans
OIO78_18875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIO78_18880	COG0657	acetylesterase activity
OIO78_18900	COG0583	DNA-binding transcription factor activity
OIO78_18930	COG2951	lytic endotransglycosylase activity
OIO78_18935	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIO78_18950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIO78_18960	COG0671	phosphoesterase, PA-phosphatase related
OIO78_18965	COG0861	Integral membrane protein TerC family
OIO78_18975	COG0754	glutathionylspermidine amidase activity
OIO78_18985	COG0402	S-adenosylhomocysteine deaminase activity
OIO78_19000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO78_19005	COG1230	cation diffusion facilitator family transporter
OIO78_19020	COG0706	membrane insertase activity
OIO78_19040	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO78_19125	COG4683	PFAM Phage derived protein Gp49-like (DUF891)