locus-tag	class	description
OIO64_00010	COG0592	DNA-directed DNA polymerase activity
OIO64_00020	COG0187	DNA topoisomerase II activity
OIO64_00030	COG0586	Pfam SNARE associated Golgi protein
OIO64_00035	COG0488	(ABC) transporter
OIO64_00060	COG0596	Alpha beta hydrolase
OIO64_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OIO64_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO64_00110	COG1047	Peptidyl-prolyl cis-trans
OIO64_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIO64_00125	COG0196	riboflavin kinase activity
OIO64_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO64_00140	COG1309	transcriptional regulator
OIO64_00145	COG1116	anion transmembrane transporter activity
OIO64_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO64_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO64_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO64_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO64_00185	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_00190	COG0546	phosphoglycolate phosphatase activity
OIO64_00215	COG1017	nitric oxide dioxygenase activity
OIO64_00215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO64_00250	COG3023	N-Acetylmuramoyl-L-alanine amidase
OIO64_00255	COG0728	peptidoglycan biosynthetic process
OIO64_00285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OIO64_00305	COG0438	transferase activity, transferring glycosyl groups
OIO64_00315	COG0438	transferase activity, transferring glycosyl groups
OIO64_00320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OIO64_00330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OIO64_00340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIO64_00355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO64_00360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO64_00370	COG2186	Transcriptional regulator
OIO64_00380	COG0277	FAD linked oxidase domain protein
OIO64_00385	COG1448	Aminotransferase
OIO64_00395	COG1802	Transcriptional regulator
OIO64_00410	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIO64_00435	COG1051	belongs to the nudix hydrolase family
OIO64_00465	COG0564	pseudouridine synthase activity
OIO64_00505	COG0251	oxidation-reduction process
OIO64_00510	COG1113	amino acid transport
OIO64_00515	COG1113	amino acid transport
OIO64_00535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO64_00540	COG1960	acyl-CoA dehydrogenase activity
OIO64_00545	COG1024	Enoyl-CoA hydratase
OIO64_00550	COG1024	Enoyl-CoA hydratase
OIO64_00555	COG0477	Major facilitator Superfamily
OIO64_00560	COG3916	Acyl-homoserine-lactone synthase
OIO64_00570	COG2197	response regulator
OIO64_00580	COG1960	acyl-CoA dehydrogenase activity
OIO64_00585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIO64_00585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OIO64_00585	COG3321	synthase
OIO64_00585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO64_00605	COG2267	carboxylic ester hydrolase activity
OIO64_00625	COG0271	Belongs to the BolA IbaG family
OIO64_00635	COG1192	Involved in chromosome partitioning
OIO64_00650	COG0586	Pfam SNARE associated Golgi protein
OIO64_00655	COG2259	Doxx family
OIO64_00660	COG4399	Belongs to the UPF0754 family
OIO64_00665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO64_00665	COG0519	Catalyzes the synthesis of GMP from XMP
OIO64_00710	COG0281	malic enzyme
OIO64_00720	COG2837	iron assimilation
OIO64_00725	COG1280	lysine exporter protein (LysE YggA)
OIO64_00730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIO64_00735	COG1121	(ABC) transporter
OIO64_00800	COG0386	Belongs to the glutathione peroxidase family
OIO64_00815	COG1309	transcriptional regulator
OIO64_00820	COG0697	spore germination
OIO64_00830	COG0758	DNA mediated transformation
OIO64_00900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIO64_00910	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIO64_00950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO64_00955	COG3757	hydrolase, family 25
OIO64_00960	COG0477	Major facilitator Superfamily
OIO64_00970	COG1253	flavin adenine dinucleotide binding
OIO64_00980	COG2860	membrane
OIO64_00985	COG0477	Major facilitator Superfamily
OIO64_00995	COG0318	PFAM AMP-dependent synthetase and ligase
OIO64_01010	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIO64_01035	COG1061	Type III restriction enzyme res subunit
OIO64_01040	COG1002	Type II restriction enzyme, methylase subunits
OIO64_01065	COG0347	Belongs to the P(II) protein family
OIO64_01070	COG0004	ammonium transporteR
OIO64_01080	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO64_01080	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO64_01120	COG0795	lipopolysaccharide-transporting ATPase activity
OIO64_01125	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIO64_01130	COG0793	Belongs to the peptidase S41A family
OIO64_01145	COG2197	response regulator
OIO64_01155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIO64_01165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO64_01170	COG4974	Belongs to the 'phage' integrase family
OIO64_01195	COG0772	Belongs to the SEDS family
OIO64_01200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO64_01205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OIO64_01210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO64_01255	COG0589	response to stress
OIO64_01260	COG0659	secondary active sulfate transmembrane transporter activity
OIO64_01270	COG1002	Type II restriction enzyme, methylase subunits
OIO64_01275	COG1061	Type III restriction enzyme res subunit
OIO64_01320	COG0697	spore germination
OIO64_01325	COG1538	Outer membrane efflux protein
OIO64_01345	COG3275	phosphorelay sensor kinase activity
OIO64_01355	COG0181	hydroxymethylbilane synthase activity
OIO64_01400	COG1716	ATPase activity
OIO64_01405	COG0546	phosphoglycolate phosphatase activity
OIO64_01505	COG2056	Na+-H+ antiporter family
OIO64_01520	COG0326	Molecular chaperone. Has ATPase activity
OIO64_01535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIO64_01595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIO64_01600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO64_01600	COG2169	Transcriptional regulator
OIO64_01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIO64_01640	COG0497	DNA recombination
OIO64_01655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO64_01665	COG0237	dephospho-CoA kinase activity
OIO64_01715	COG0195	Participates in both transcription termination and antitermination
OIO64_01730	COG1320	monovalent cation:proton antiporter activity
OIO64_01735	COG2212	antiporter activity
OIO64_01740	COG1863	multisubunit Na H antiporter MnhE subunit
OIO64_01745	COG0651	ATP synthesis coupled electron transport
OIO64_01750	COG1006	Multisubunit Na H antiporter MnhC subunit
OIO64_01755	COG2111	Na H antiporter
OIO64_01755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO64_01770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIO64_01790	COG2226	methyltransferase
OIO64_01810	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OIO64_01815	COG1074	ATP-dependent DNA helicase activity
OIO64_01820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO64_01825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO64_01840	COG0598	Magnesium transport protein CorA
OIO64_01845	COG0789	Transcriptional regulator
OIO64_01850	COG0484	heat shock protein binding
OIO64_01865	COG0475	glutathione-regulated potassium exporter activity
OIO64_01865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO64_01870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIO64_01890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO64_01900	COG4535	Mg2 and Co2 transporter CorC
OIO64_01905	COG0425	Belongs to the sulfur carrier protein TusA family
OIO64_01915	COG0644	oxidoreductase
OIO64_01915	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OIO64_01925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO64_01940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO64_01945	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OIO64_01955	COG0493	'glutamate synthase
OIO64_01955	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO64_01980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OIO64_01995	COG0534	Mate efflux family protein
OIO64_02005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIO64_02010	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_02015	COG0583	DNA-binding transcription factor activity
OIO64_02030	COG0318	PFAM AMP-dependent synthetase and ligase
OIO64_02035	COG1530	ribonuclease E activity
OIO64_02045	COG0546	phosphoglycolate phosphatase activity
OIO64_02050	COG2378	regulation of single-species biofilm formation
OIO64_02055	COG0625	glutathione transferase activity
OIO64_02065	COG0583	DNA-binding transcription factor activity
OIO64_02120	COG0473	3-isopropylmalate dehydrogenase activity
OIO64_02175	COG1301	dicarboxylic acid transport
OIO64_02185	COG1560	Kdo2-lipid A biosynthetic process
OIO64_02190	COG1280	lysine exporter protein (LysE YggA)
OIO64_02195	COG0488	(ABC) transporter
OIO64_02200	COG2900	Belongs to the SlyX family
OIO64_02210	COG1733	regulation of RNA biosynthetic process
OIO64_02235	COG0210	DNA helicase
OIO64_02240	COG0724	RNA recognition motif
OIO64_02260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO64_02260	COG4651	solute:proton antiporter activity
OIO64_02285	COG0788	formyltetrahydrofolate deformylase activity
OIO64_02385	COG2813	Specifically methylates the guanine in position
OIO64_02385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO64_02395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO64_02405	COG4774	siderophore transport
OIO64_02415	COG0740	serine-type endopeptidase activity
OIO64_02435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO64_02435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO64_02440	COG0280	phosphate acetyltransferase
OIO64_02440	COG0857	belongs to the CobB CobQ family
OIO64_02445	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIO64_02455	COG0800	Aldolase
OIO64_02465	COG3265	gluconokinase activity
OIO64_02470	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_02480	COG2267	carboxylic ester hydrolase activity
OIO64_02495	COG0793	Belongs to the peptidase S41A family
OIO64_02530	COG1426	Protein conserved in bacteria
OIO64_02570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OIO64_02580	COG1162	GTPase activity
OIO64_02585	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIO64_02600	COG1538	Outer membrane efflux protein
OIO64_02605	COG0577	efflux transmembrane transporter activity
OIO64_02605	COG1136	(ABC) transporter
OIO64_02610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO64_02635	COG0028	Belongs to the TPP enzyme family
OIO64_02640	COG0440	acetolactate synthase activity
OIO64_02670	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIO64_02685	COG0084	hydrolase, TatD family'
OIO64_02695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OIO64_02705	COG0583	DNA-binding transcription factor activity
OIO64_02715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO64_02785	COG1294	oxidase, subunit
OIO64_02790	COG1271	oxidase subunit
OIO64_02805	COG4774	siderophore transport
OIO64_02875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO64_02885	COG2814	Major facilitator Superfamily
OIO64_02895	COG0697	spore germination
OIO64_02930	COG3622	Belongs to the hyi family
OIO64_02935	COG2084	Dehydrogenase
OIO64_02940	COG1024	Enoyl-CoA hydratase
OIO64_02945	COG5002	protein histidine kinase activity
OIO64_02945	COG0784	Response regulator, receiver
OIO64_02945	COG2205	protein histidine kinase activity
OIO64_02965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO64_02975	COG3956	TIGRFAM MazG family protein
OIO64_02980	COG1555	photosystem II stabilization
OIO64_02985	COG0617	tRNA 3'-terminal CCA addition
OIO64_02990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OIO64_03010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO64_03015	COG3028	Belongs to the UPF0307 family
OIO64_03020	COG0318	PFAM AMP-dependent synthetase and ligase
OIO64_03035	COG0625	glutathione transferase activity
OIO64_03040	COG1238	metal cluster binding
OIO64_03085	COG0072	phenylalanine-tRNA ligase activity
OIO64_03115	COG0248	Ppx GppA phosphatase
OIO64_03125	COG0037	tRNA processing
OIO64_03165	COG1764	response to oxidative stress
OIO64_03170	COG1846	Transcriptional regulator
OIO64_03180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO64_03240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIO64_03245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIO64_03250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIO64_03320	COG1214	PFAM Peptidase M22, glycoprotease
OIO64_03335	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO64_03345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIO64_03350	COG0561	phosphatase activity
OIO64_03360	COG2132	Multicopper oxidase
OIO64_03380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO64_03385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIO64_03390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIO64_03420	COG1063	alcohol dehydrogenase
OIO64_03425	COG0583	DNA-binding transcription factor activity
OIO64_03430	COG1960	acyl-CoA dehydrogenase activity
OIO64_03435	COG2814	Major facilitator Superfamily
OIO64_03440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO64_03450	COG1053	succinate dehydrogenase
OIO64_03455	COG0583	DNA-binding transcription factor activity
OIO64_03470	COG0583	DNA-binding transcription factor activity
OIO64_03480	COG0583	DNA-binding transcription factor activity
OIO64_03495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO64_03540	COG0384	phenazine biosynthesis protein PhzF
OIO64_03560	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_03570	COG0477	Major facilitator Superfamily
OIO64_03605	COG0697	spore germination
OIO64_03610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO64_03630	COG0745	RESPONSE REGULATOR receiver
OIO64_03670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIO64_03700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO64_03705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIO64_03730	COG0583	DNA-binding transcription factor activity
OIO64_03750	COG0668	transmembrane transport
OIO64_03760	COG2081	HI0933 family
OIO64_03765	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO64_03795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO64_03795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO64_03805	COG0489	protein tyrosine kinase activity
OIO64_03855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO64_03865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIO64_03880	COG0730	response to heat
OIO64_03890	COG1196	nuclear chromosome segregation
OIO64_03910	COG2223	nitrite transmembrane transporter activity
OIO64_03915	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OIO64_03920	COG1877	trehalose-phosphatase activity
OIO64_03925	COG0596	Alpha beta hydrolase
OIO64_03925	COG2226	methyltransferase
OIO64_03925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO64_03940	COG4106	trans-aconitate 2-methyltransferase activity
OIO64_03955	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIO64_03960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIO64_03965	COG0009	L-threonylcarbamoyladenylate synthase
OIO64_03970	COG3101	peptidyl-lysine hydroxylation
OIO64_03975	COG1399	metal-binding, possibly nucleic acid-binding protein
OIO64_04000	COG1652	LysM domain
OIO64_04005	COG0351	phosphomethylpyrimidine kinase
OIO64_04005	COG0352	thiamine-phosphate diphosphorylase activity
OIO64_04005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO64_04015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIO64_04045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO64_04075	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OIO64_04090	COG0358	DNA primase activity
OIO64_04100	COG0564	pseudouridine synthase activity
OIO64_04125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO64_04155	COG0583	DNA-binding transcription factor activity
OIO64_04160	COG0473	3-isopropylmalate dehydrogenase activity
OIO64_04170	COG0657	acetylesterase activity
OIO64_04180	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_04200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIO64_04200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO64_04215	COG1981	membrane
OIO64_04260	COG0456	acetyltransferase
OIO64_04270	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OIO64_04275	COG0492	ferredoxin-NADP+ reductase activity
OIO64_04280	COG1674	ftsk spoiiie
OIO64_04280	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OIO64_04285	COG1280	lysine exporter protein (LysE YggA)
OIO64_04300	COG2894	cell division
OIO64_04315	COG0204	Acyl-transferase
OIO64_04320	COG2885	chlorophyll binding
OIO64_04325	COG0210	DNA helicase
OIO64_04335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO64_04350	COG0121	glutamine amidotransferase
OIO64_04370	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO64_04375	COG0735	belongs to the Fur family
OIO64_04400	COG0420	3'-5' exonuclease activity
OIO64_04420	COG1090	epimerase
OIO64_04435	COG2050	protein possibly involved in aromatic compounds catabolism
OIO64_04445	COG2814	Major facilitator Superfamily
OIO64_04450	COG0405	Gamma-glutamyltransferase
OIO64_04530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO64_04615	COG1484	DNA-dependent DNA replication
OIO64_04835	COG2026	Addiction module toxin, RelE StbE family
OIO64_04875	COG0592	DNA-directed DNA polymerase activity
OIO64_04960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO64_05020	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OIO64_05030	COG0477	Major facilitator Superfamily
OIO64_05035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO64_05045	COG1595	DNA-templated transcription, initiation
OIO64_05100	COG0531	amino acid
OIO64_05105	COG2040	homocysteine
OIO64_05130	COG1309	transcriptional regulator
OIO64_05135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO64_05140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO64_05150	COG1607	acyl-coa hydrolase
OIO64_05160	COG0523	cobalamin synthesis protein
OIO64_05170	COG4681	YaeQ
OIO64_05180	COG1649	PFAM Uncharacterised BCR, COG1649
OIO64_05180	COG0726	polysaccharide deacetylase
OIO64_05185	COG1215	transferase activity, transferring glycosyl groups
OIO64_05195	COG1024	Enoyl-CoA hydratase
OIO64_05210	COG1414	Transcriptional regulator
OIO64_05230	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_05240	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO64_05245	COG2271	Major facilitator Superfamily
OIO64_05255	COG2267	carboxylic ester hydrolase activity
OIO64_05260	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_05275	COG0028	Belongs to the TPP enzyme family
OIO64_05285	COG0477	Major facilitator Superfamily
OIO64_05290	COG0242	peptide deformylase activity
OIO64_05295	COG2066	Belongs to the glutaminase family
OIO64_05300	COG2207	Transcriptional regulator
OIO64_05320	COG0583	DNA-binding transcription factor activity
OIO64_05325	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_05330	COG2271	Major facilitator Superfamily
OIO64_05335	COG3959	Transketolase, thiamine diphosphate binding domain
OIO64_05340	COG3958	Transketolase
OIO64_05350	COG0306	phosphate transporter
OIO64_05375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIO64_05420	COG4181	ATPase activity
OIO64_05425	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OIO64_05455	COG0583	DNA-binding transcription factor activity
OIO64_05465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO64_05470	COG1773	rubredoxin
OIO64_05520	COG2851	Citrate transporter
OIO64_05525	COG1253	flavin adenine dinucleotide binding
OIO64_05565	COG0804	urea catabolic process
OIO64_05575	COG0830	nickel cation binding
OIO64_05590	COG0742	ribosomal rna small subunit methyltransferase
OIO64_05595	COG0768	penicillin binding
OIO64_05620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIO64_05625	COG2878	Part of a membrane complex involved in electron transport
OIO64_05630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO64_05640	COG3384	dioxygenase
OIO64_05660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIO64_05840	COG5410	chromosome segregation
OIO64_06005	COG2194	sulfuric ester hydrolase activity
OIO64_06040	COG0006	proline dipeptidase activity
OIO64_06045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO64_06050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO64_06070	COG1279	arginine transmembrane transporter activity
OIO64_06075	COG0583	DNA-binding transcription factor activity
OIO64_06115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO64_06120	COG1388	LysM domain
OIO64_06120	COG1388	LysM domain
OIO64_06120	COG0741	lytic transglycosylase activity
OIO64_06120	COG0741	lytic transglycosylase activity
OIO64_06130	COG4174	ABC transporter (Permease)
OIO64_06135	COG4239	(ABC) transporter, permease
OIO64_06140	COG4172	Belongs to the ABC transporter superfamily
OIO64_06165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO64_06175	COG3706	GGDEF domain
OIO64_06175	COG4251	negative regulation of phosphorylation
OIO64_06175	COG2203	Gaf domain
OIO64_06175	COG5001	Diguanylate cyclase
OIO64_06185	COG1902	pentaerythritol trinitrate reductase activity
OIO64_06185	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO64_06200	COG4269	membrane
OIO64_06220	COG3209	COG3209 Rhs family protein
OIO64_06260	COG1113	amino acid transport
OIO64_06270	COG0531	amino acid
OIO64_06290	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_06310	COG1113	amino acid transport
OIO64_06355	COG0697	spore germination
OIO64_06360	COG2721	sulfolactate sulfo-lyase activity
OIO64_06365	COG2271	Major facilitator Superfamily
OIO64_06370	COG4948	Mandelate Racemase Muconate Lactonizing
OIO64_06380	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_06385	COG2186	Transcriptional regulator
OIO64_06410	COG1960	acyl-CoA dehydrogenase activity
OIO64_06420	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_06425	COG1024	Enoyl-CoA hydratase
OIO64_06430	COG2814	Major facilitator Superfamily
OIO64_06450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO64_06495	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIO64_06500	COG2072	flavoprotein involved in K transport
OIO64_06505	COG0300	oxidoreductase activity
OIO64_06515	COG1309	transcriptional regulator
OIO64_06520	COG1741	Belongs to the pirin family
OIO64_06535	COG2072	flavoprotein involved in K transport
OIO64_06545	COG2252	PERMEase
OIO64_06550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIO64_06555	COG3038	cytochrome b561
OIO64_06565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIO64_06575	COG0527	aspartate kinase activity
OIO64_06585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIO64_06600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIO64_06615	COG0667	Aldo Keto reductase
OIO64_06630	COG1765	OsmC-like protein
OIO64_06645	COG0542	response to heat
OIO64_06680	COG2885	chlorophyll binding
OIO64_06690	COG0625	glutathione transferase activity
OIO64_06855	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIO64_06875	COG3634	alkyl hydroperoxide reductase activity
OIO64_06885	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIO64_06895	COG0450	alkyl hydroperoxide reductase
OIO64_06900	COG1643	Atp-dependent helicase
OIO64_06915	COG2814	Major facilitator Superfamily
OIO64_06920	COG3135	benzoate transporter
OIO64_06925	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_06930	COG0543	2 iron, 2 sulfur cluster binding
OIO64_06930	COG0633	Ferredoxin
OIO64_06940	COG4638	Rieske (2fe-2S)
OIO64_06950	COG0583	DNA-binding transcription factor activity
OIO64_07000	COG1570	exodeoxyribonuclease VII activity
OIO64_07030	COG1280	lysine exporter protein (LysE YggA)
OIO64_07035	COG1278	Cold shock
OIO64_07070	COG2814	Major facilitator Superfamily
OIO64_07110	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OIO64_07110	COG0517	IMP dehydrogenase activity
OIO64_07115	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OIO64_07125	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OIO64_07130	COG1137	ATPase activity
OIO64_07165	COG4122	O-methyltransferase activity
OIO64_07175	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OIO64_07190	COG1522	sequence-specific DNA binding
OIO64_07195	COG5006	permease, DMT superfamily
OIO64_07205	COG1560	Kdo2-lipid A biosynthetic process
OIO64_07215	COG0598	Magnesium transport protein CorA
OIO64_07245	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO64_07250	COG1116	anion transmembrane transporter activity
OIO64_07255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO64_07280	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO64_07340	COG1914	H( )-stimulated, divalent metal cation uptake system
OIO64_07360	COG4770	biotin carboxylase activity
OIO64_07365	COG0038	chloride channel
OIO64_07405	COG1309	transcriptional regulator
OIO64_07415	COG1063	alcohol dehydrogenase
OIO64_07430	COG0439	Biotin carboxylase
OIO64_07435	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO64_07440	COG1733	regulation of RNA biosynthetic process
OIO64_07450	COG0864	Transcriptional regulator
OIO64_07460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO64_07465	COG1116	anion transmembrane transporter activity
OIO64_07595	COG0590	tRNA wobble adenosine to inosine editing
OIO64_07600	COG2807	transmembrane transport
OIO64_07615	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OIO64_07625	COG0789	Transcriptional regulator
OIO64_07635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO64_07655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO64_07680	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_07685	COG0531	amino acid
OIO64_07690	COG1760	l-serine dehydratase
OIO64_07695	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_07695	COG2030	dehydratase
OIO64_07700	COG3396	Phenylacetate-CoA oxygenase
OIO64_07705	COG3460	Phenylacetate-CoA oxygenase
OIO64_07710	COG3396	Phenylacetate-CoA oxygenase
OIO64_07715	COG2151	metal-sulfur cluster biosynthetic enzyme
OIO64_07720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO64_07725	COG1024	Enoyl-CoA hydratase
OIO64_07730	COG1024	Enoyl-CoA hydratase
OIO64_07735	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO64_07740	COG0183	Belongs to the thiolase family
OIO64_07745	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OIO64_07750	COG3327	negative regulation of DNA-templated transcription, initiation
OIO64_07760	COG2050	protein possibly involved in aromatic compounds catabolism
OIO64_07770	COG0556	nucleotide-excision repair
OIO64_07805	COG1278	Cold shock
OIO64_07815	COG2207	Transcriptional regulator
OIO64_07915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO64_07920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO64_07925	COG2271	Major facilitator Superfamily
OIO64_07930	COG0753	catalase activity
OIO64_07935	COG3038	cytochrome b561
OIO64_07955	COG2267	carboxylic ester hydrolase activity
OIO64_07960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO64_07965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO64_07970	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_07980	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO64_07990	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_07995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO64_08000	COG0583	DNA-binding transcription factor activity
OIO64_08010	COG1414	Transcriptional regulator
OIO64_08015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO64_08030	COG1840	ABC-type Fe3 transport system, periplasmic component
OIO64_08035	COG3842	ATPase activity
OIO64_08055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO64_08075	COG0583	DNA-binding transcription factor activity
OIO64_08085	COG4770	biotin carboxylase activity
OIO64_08090	COG1024	Enoyl-CoA hydratase
OIO64_08095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO64_08100	COG1960	acyl-CoA dehydrogenase activity
OIO64_08105	COG1309	transcriptional regulator
OIO64_08110	COG0318	PFAM AMP-dependent synthetase and ligase
OIO64_08130	COG0583	DNA-binding transcription factor activity
OIO64_08180	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_08200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIO64_08220	COG2205	protein histidine kinase activity
OIO64_08220	COG0784	Response regulator, receiver
OIO64_08240	COG0765	amino acid transport
OIO64_08245	COG0765	amino acid transport
OIO64_08250	COG1126	abc transporter atp-binding protein
OIO64_08255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO64_08260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO64_08275	COG1280	lysine exporter protein (LysE YggA)
OIO64_08285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIO64_08290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO64_08295	COG1045	serine acetyltransferase
OIO64_08305	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_08310	COG0583	DNA-binding transcription factor activity
OIO64_08315	COG0625	glutathione transferase activity
OIO64_08320	COG0625	glutathione transferase activity
OIO64_08325	COG0583	DNA-binding transcription factor activity
OIO64_08335	COG1346	cytolysis
OIO64_08355	COG2814	Major facilitator Superfamily
OIO64_08365	COG0583	DNA-binding transcription factor activity
OIO64_08375	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OIO64_08380	COG3052	prosthetic group binding
OIO64_08400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OIO64_08420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO64_08430	COG1294	oxidase, subunit
OIO64_08435	COG1271	oxidase subunit
OIO64_08455	COG0477	Major facilitator Superfamily
OIO64_08465	COG4521	taurine ABC transporter
OIO64_08485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO64_08490	COG2175	clavaminate synthase activity
OIO64_08500	COG1953	Uracil, thiamine, allantoin
OIO64_08510	COG0583	DNA-binding transcription factor activity
OIO64_08520	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIO64_08535	COG0640	Transcriptional regulator
OIO64_08540	COG0798	PFAM Bile acid sodium symporter
OIO64_08545	COG0583	DNA-binding transcription factor activity
OIO64_08560	COG3634	alkyl hydroperoxide reductase activity
OIO64_08595	COG1301	dicarboxylic acid transport
OIO64_08600	COG0436	Aminotransferase
OIO64_08610	COG0386	Belongs to the glutathione peroxidase family
OIO64_08650	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO64_08675	COG0012	GTP binding
OIO64_08680	COG2011	ABC-type metal ion transport system permease component
OIO64_08685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO64_08695	COG1464	Belongs to the NlpA lipoprotein family
OIO64_08725	COG0765	amino acid transport
OIO64_08730	COG0765	amino acid transport
OIO64_08735	COG1126	abc transporter atp-binding protein
OIO64_08745	COG1522	sequence-specific DNA binding
OIO64_08760	COG1309	transcriptional regulator
OIO64_08780	COG0583	DNA-binding transcription factor activity
OIO64_08790	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO64_08800	COG0697	spore germination
OIO64_08825	COG3121	Chaperone
OIO64_08830	COG3539	Fimbrial protein
OIO64_08855	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIO64_08855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIO64_08900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIO64_08910	COG2353	YceI-like domain
OIO64_08920	COG3698	Phosphodiester glycosidase
OIO64_08935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIO64_08940	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO64_08940	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO64_08940	COG0506	proline dehydrogenase activity
OIO64_08950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO64_08955	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIO64_08975	COG1132	(ABC) transporter
OIO64_08980	COG3122	Protein conserved in bacteria
OIO64_08985	COG3619	membrane
OIO64_08995	COG0640	Transcriptional regulator
OIO64_09005	COG2850	peptidyl-arginine hydroxylation
OIO64_09010	COG0424	maF-like protein
OIO64_09030	COG0191	fructose-bisphosphate aldolase activity
OIO64_09035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO64_09050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIO64_09060	COG1192	Involved in chromosome partitioning
OIO64_09065	COG1475	DNA binding
OIO64_09070	COG0811	peptide transport
OIO64_09080	COG1132	(ABC) transporter
OIO64_09085	COG1663	tetraacyldisaccharide 4'-kinase activity
OIO64_09105	COG0084	hydrolase, TatD family'
OIO64_09170	COG0776	regulation of translation
OIO64_09200	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OIO64_09205	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIO64_09240	COG4166	transmembrane transport
OIO64_09250	COG0339	signal peptide processing
OIO64_09260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIO64_09295	COG0702	epimerase
OIO64_09300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO64_09320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO64_09350	COG0316	Belongs to the HesB IscA family
OIO64_09355	COG0822	iron-sulfur transferase activity
OIO64_09380	COG0776	regulation of translation
OIO64_09385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO64_09390	COG2207	Transcriptional regulator
OIO64_09395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO64_09400	COG1960	acyl-CoA dehydrogenase activity
OIO64_09405	COG1960	acyl-CoA dehydrogenase activity
OIO64_09420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIO64_09435	COG2814	Major facilitator Superfamily
OIO64_09440	COG4264	IucA IucC family
OIO64_09445	COG4264	IucA IucC family
OIO64_09455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO64_09485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO64_09500	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIO64_09505	COG0406	alpha-ribazole phosphatase activity
OIO64_09520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO64_09525	COG0730	response to heat
OIO64_09550	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO64_09565	COG1131	(ABC) transporter
OIO64_09570	COG0842	Transport permease protein
OIO64_09575	COG0842	Transport permease protein
OIO64_09630	COG2226	methyltransferase
OIO64_09655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIO64_09690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO64_09700	COG0133	tryptophan synthase activity
OIO64_09715	COG3706	GGDEF domain
OIO64_09730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO64_09735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OIO64_09740	COG0022	dehydrogenase e1 component
OIO64_09745	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO64_09750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO64_09760	COG1063	alcohol dehydrogenase
OIO64_09765	COG3781	membrane
OIO64_09775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO64_09775	COG3453	Protein conserved in bacteria
OIO64_09790	COG0730	response to heat
OIO64_09805	COG2207	Transcriptional regulator
OIO64_09805	COG3708	Transcriptional regulator
OIO64_09810	COG1733	regulation of RNA biosynthetic process
OIO64_09815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIO64_09825	COG2188	Transcriptional regulator
OIO64_09840	COG4521	taurine ABC transporter
OIO64_09845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO64_09865	COG0477	Major facilitator Superfamily
OIO64_09875	COG1027	Aspartate ammonia-lyase
OIO64_09895	COG0583	DNA-binding transcription factor activity
OIO64_09900	COG0583	DNA-binding transcription factor activity
OIO64_09905	COG0183	Belongs to the thiolase family
OIO64_09910	COG2031	fatty acid transporter
OIO64_09925	COG0583	DNA-binding transcription factor activity
OIO64_09935	COG2610	gluconate transmembrane transporter activity
OIO64_09940	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_09945	COG2207	Transcriptional regulator
OIO64_09960	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_09970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO64_09985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO64_09985	COG0543	2 iron, 2 sulfur cluster binding
OIO64_09990	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO64_09995	COG4638	Rieske (2fe-2S)
OIO64_10005	COG0725	ABC transporter, periplasmic molybdate-binding protein
OIO64_10010	COG4149	molybdate abc transporter
OIO64_10015	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OIO64_10020	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_10025	COG1535	isochorismatase
OIO64_10025	COG3433	isochorismatase activity
OIO64_10085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO64_10105	COG0753	catalase activity
OIO64_10115	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO64_10140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO64_10145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO64_10150	COG0745	RESPONSE REGULATOR receiver
OIO64_10155	COG2205	protein histidine kinase activity
OIO64_10165	COG2207	Transcriptional regulator
OIO64_10175	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_10205	COG3320	Male sterility
OIO64_10205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO64_10210	COG2814	Major facilitator Superfamily
OIO64_10235	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OIO64_10285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO64_10305	COG1120	ATPase activity
OIO64_10310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO64_10320	COG1064	alcohol dehydrogenase
OIO64_10335	COG2207	Transcriptional regulator
OIO64_10340	COG2084	Dehydrogenase
OIO64_10350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO64_10355	COG0583	DNA-binding transcription factor activity
OIO64_10365	COG0129	dihydroxy-acid dehydratase activity
OIO64_10370	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_10375	COG1846	Transcriptional regulator
OIO64_10380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO64_10385	COG1960	acyl-CoA dehydrogenase activity
OIO64_10390	COG0477	Major facilitator Superfamily
OIO64_10405	COG3971	2-oxopent-4-enoate hydratase activity
OIO64_10415	COG3384	dioxygenase
OIO64_10420	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_10430	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO64_10440	COG2814	Major facilitator Superfamily
OIO64_10445	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO64_10460	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_10480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO64_10500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO64_10535	COG0583	DNA-binding transcription factor activity
OIO64_10550	COG2188	Transcriptional regulator
OIO64_10605	COG1473	amidohydrolase
OIO64_10615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO64_10615	COG0475	glutathione-regulated potassium exporter activity
OIO64_10625	COG0583	DNA-binding transcription factor activity
OIO64_10630	COG1335	isochorismatase
OIO64_10640	COG1309	transcriptional regulator
OIO64_10675	COG1902	pentaerythritol trinitrate reductase activity
OIO64_10675	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO64_10680	COG1846	Transcriptional regulator
OIO64_10705	COG0753	catalase activity
OIO64_10720	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_10735	COG3162	membrane
OIO64_10745	COG3829	transcription factor binding
OIO64_10750	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_10755	COG1960	acyl-CoA dehydrogenase activity
OIO64_10770	COG3231	kanamycin kinase activity
OIO64_10775	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_10795	COG2186	Transcriptional regulator
OIO64_10805	COG0583	DNA-binding transcription factor activity
OIO64_10810	COG4948	Mandelate Racemase Muconate Lactonizing
OIO64_10815	COG4829	muconolactone delta-isomerase
OIO64_10825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO64_10830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO64_10835	COG0183	Belongs to the thiolase family
OIO64_10840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO64_10850	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_10860	COG3733	amine oxidase
OIO64_10870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO64_10880	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_10890	COG4638	Rieske (2fe-2S)
OIO64_10910	COG0154	amidase activity
OIO64_10920	COG2814	Major facilitator Superfamily
OIO64_10945	COG1960	acyl-CoA dehydrogenase activity
OIO64_10950	COG0583	DNA-binding transcription factor activity
OIO64_10955	COG1414	Transcriptional regulator
OIO64_10970	COG2391	methyltransferase activity
OIO64_10980	COG4993	Dehydrogenase
OIO64_10985	COG3659	wide pore channel activity
OIO64_10990	COG3420	alginic acid biosynthetic process
OIO64_10995	COG0710	3-dehydroquinate dehydratase activity
OIO64_11000	COG3485	protocatechuate 3,4-dioxygenase
OIO64_11005	COG3485	protocatechuate 3,4-dioxygenase
OIO64_11010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO64_11015	COG2271	Major facilitator Superfamily
OIO64_11020	COG0596	Alpha beta hydrolase
OIO64_11025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIO64_11030	COG0183	Belongs to the thiolase family
OIO64_11035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO64_11040	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO64_11050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OIO64_11055	COG2323	membrane
OIO64_11100	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO64_11100	COG1902	pentaerythritol trinitrate reductase activity
OIO64_11115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO64_11125	COG0542	response to heat
OIO64_11130	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIO64_11160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO64_11165	COG0569	domain protein
OIO64_11170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIO64_11185	COG4774	siderophore transport
OIO64_11190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIO64_11200	COG1585	Membrane protein implicated in regulation of membrane protease activity
OIO64_11215	COG1294	oxidase, subunit
OIO64_11220	COG4890	Cyd operon protein YbgT
OIO64_11230	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OIO64_11240	COG0552	protein localization to endoplasmic reticulum
OIO64_11265	COG0517	IMP dehydrogenase activity
OIO64_11265	COG0516	GMP reductase activity
OIO64_11270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO64_11275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OIO64_11285	COG0583	DNA-binding transcription factor activity
OIO64_11290	COG0024	Methionine aminopeptidase
OIO64_11320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO64_11320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIO64_11325	COG1105	Belongs to the carbohydrate kinase PfkB family
OIO64_11330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO64_11330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO64_11330	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIO64_11350	COG3300	MHYT domain
OIO64_11350	COG5001	Diguanylate cyclase
OIO64_11365	COG2135	peptidase activity
OIO64_11370	COG0659	secondary active sulfate transmembrane transporter activity
OIO64_11390	COG1113	amino acid transport
OIO64_11400	COG1522	sequence-specific DNA binding
OIO64_11425	COG1011	Hydrolase
OIO64_11430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OIO64_11440	COG2137	regulation of response to DNA damage stimulus
OIO64_11455	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO64_11475	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO64_11490	COG0575	Belongs to the CDS family
OIO64_11495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIO64_11515	COG3852	Histidine kinase
OIO64_11520	COG2204	response regulator
OIO64_11575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO64_11580	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OIO64_11600	COG0697	spore germination
OIO64_11605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO64_11620	COG0315	cyclic pyranopterin monophosphate synthase activity
OIO64_11620	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIO64_11640	COG0243	molybdopterin cofactor binding
OIO64_11650	COG0243	molybdopterin cofactor binding
OIO64_11655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO64_11660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO64_11660	COG2146	nitrite reductase [NAD(P)H] activity
OIO64_11670	COG0745	RESPONSE REGULATOR receiver
OIO64_11675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO64_11675	COG1116	anion transmembrane transporter activity
OIO64_11695	COG0511	ligase activity, forming carbon-carbon bonds
OIO64_11710	COG2814	Major facilitator Superfamily
OIO64_11730	COG0069	glutamate synthase activity
OIO64_11750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIO64_11760	COG1454	alcohol dehydrogenase
OIO64_11765	COG0824	Thioesterase
OIO64_11775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIO64_11790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO64_11795	COG2030	dehydratase
OIO64_11805	COG0183	Belongs to the thiolase family
OIO64_11815	COG0583	DNA-binding transcription factor activity
OIO64_11820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIO64_11830	COG1522	sequence-specific DNA binding
OIO64_11835	COG3135	benzoate transporter
OIO64_11845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIO64_11870	COG0589	response to stress
OIO64_11875	COG0488	(ABC) transporter
OIO64_11895	COG4773	Receptor
OIO64_11925	COG0668	transmembrane transport
OIO64_11935	COG1309	transcriptional regulator
OIO64_11955	COG1605	Chorismate mutase
OIO64_11975	COG0308	aminopeptidase N
OIO64_11995	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OIO64_12005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO64_12010	COG1454	alcohol dehydrogenase
OIO64_12030	COG0531	amino acid
OIO64_12035	COG4303	Ethanolamine ammonia lyase large subunit
OIO64_12040	COG4302	ethanolamine ammonia-lyase activity
OIO64_12045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO64_12045	COG0519	Catalyzes the synthesis of GMP from XMP
OIO64_12050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO64_12075	COG0697	spore germination
OIO64_12080	COG1923	regulation of RNA biosynthetic process
OIO64_12090	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIO64_12095	COG0802	atpase or kinase
OIO64_12115	COG1187	pseudouridine synthase activity
OIO64_12130	COG0583	DNA-binding transcription factor activity
OIO64_12145	COG2814	Major facilitator Superfamily
OIO64_12150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO64_12175	COG0729	surface antigen
OIO64_12195	COG0174	glutamine synthetase
OIO64_12200	COG0745	RESPONSE REGULATOR receiver
OIO64_12215	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIO64_12220	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIO64_12230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OIO64_12245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO64_12250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO64_12255	COG1960	acyl-CoA dehydrogenase activity
OIO64_12270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO64_12275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO64_12295	COG0583	DNA-binding transcription factor activity
OIO64_12310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO64_12320	COG3658	cytochrome
OIO64_12325	COG1215	transferase activity, transferring glycosyl groups
OIO64_12330	COG0726	polysaccharide deacetylase
OIO64_12330	COG1649	PFAM Uncharacterised BCR, COG1649
OIO64_12355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIO64_12360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIO64_12370	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OIO64_12395	COG0305	Participates in initiation and elongation during chromosome replication
OIO64_12400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIO64_12410	COG1305	Transglutaminase-like
OIO64_12420	COG2308	Evidence 4 Homologs of previously reported genes of
OIO64_12450	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OIO64_12455	COG0138	bifunctional purine biosynthesis protein purh
OIO64_12460	COG0151	Belongs to the GarS family
OIO64_12465	COG1464	Belongs to the NlpA lipoprotein family
OIO64_12470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO64_12475	COG2011	ABC-type metal ion transport system permease component
OIO64_12480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO64_12490	COG1301	dicarboxylic acid transport
OIO64_12520	COG1794	racemase activity, acting on amino acids and derivatives
OIO64_12530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIO64_12530	COG3008	intermembrane lipid transfer
OIO64_12535	COG2995	paraquat-inducible protein a
OIO64_12565	COG0477	Major facilitator Superfamily
OIO64_12575	COG2186	Transcriptional regulator
OIO64_12585	COG0786	glutamate:sodium symporter activity
OIO64_12590	COG3243	poly(R)-hydroxyalkanoic acid synthase
OIO64_12615	COG3111	PFAM Bacterial OB fold (BOF) protein
OIO64_12685	COG0515	serine threonine protein kinase
OIO64_12685	COG2815	serine threonine protein kinase
OIO64_12715	COG1610	YqeY-like protein
OIO64_12720	COG4783	chaperone-mediated protein folding
OIO64_12745	COG1286	toxin biosynthetic process
OIO64_12775	COG0778	Nitroreductase
OIO64_12785	COG0513	Belongs to the DEAD box helicase family
OIO64_12810	COG2363	Small membrane protein
OIO64_12840	COG4650	regulator
OIO64_12845	COG1234	tRNA 3'-trailer cleavage
OIO64_12850	COG1690	Belongs to the RtcB family
OIO64_12870	COG2195	Cleaves the N-terminal amino acid of tripeptides
OIO64_12880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIO64_12890	COG2819	hydrolase of the alpha beta superfamily
OIO64_12895	COG1960	acyl-CoA dehydrogenase activity
OIO64_12900	COG1301	dicarboxylic acid transport
OIO64_12910	COG3139	Protein of unknown function (DUF1315)
OIO64_12915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIO64_12920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIO64_12930	COG0494	nUDIX hydrolase
OIO64_12940	COG0642	Histidine kinase
OIO64_12955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OIO64_12965	COG1720	tRNA m6t6A37 methyltransferase activity
OIO64_12980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO64_12985	COG0826	peptidase U32
OIO64_12990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO64_13000	COG4598	ABC transporter
OIO64_13005	COG4160	amino acid transport
OIO64_13010	COG4215	(ABC) transporter
OIO64_13025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO64_13070	COG1131	(ABC) transporter
OIO64_13075	COG0842	Transport permease protein
OIO64_13090	COG0772	Belongs to the SEDS family
OIO64_13095	COG2951	lytic endotransglycosylase activity
OIO64_13120	COG2207	Transcriptional regulator
OIO64_13135	COG0052	Belongs to the universal ribosomal protein uS2 family
OIO64_13140	COG0024	Methionine aminopeptidase
OIO64_13160	COG2223	nitrite transmembrane transporter activity
OIO64_13170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO64_13175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO64_13180	COG1960	acyl-CoA dehydrogenase activity
OIO64_13195	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIO64_13200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIO64_13205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO64_13225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO64_13230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIO64_13235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIO64_13270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OIO64_13280	COG0174	glutamine synthetase
OIO64_13295	COG0512	Glutamine amidotransferase of anthranilate synthase
OIO64_13300	COG0308	aminopeptidase N
OIO64_13330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIO64_13340	COG0302	gtp cyclohydrolase
OIO64_13360	COG3739	integral membrane protein
OIO64_13380	COG2977	Belongs to the P-Pant transferase superfamily
OIO64_13385	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OIO64_13390	COG1132	(ABC) transporter
OIO64_13395	COG1132	(ABC) transporter
OIO64_13410	COG3433	isochorismatase activity
OIO64_13410	COG1535	isochorismatase
OIO64_13415	COG1021	2,3-dihydroxybenzoate-AMP ligase
OIO64_13420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO64_13430	COG4774	siderophore transport
OIO64_13435	COG4607	ABC-type enterochelin transport system periplasmic component
OIO64_13440	COG4604	ABC transporter, ATP-binding protein
OIO64_13445	COG4605	iron ion homeostasis
OIO64_13450	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO64_13460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO64_13475	COG2964	Protein conserved in bacteria
OIO64_13485	COG1741	Belongs to the pirin family
OIO64_13515	COG2130	NADP-dependent
OIO64_13525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO64_13535	COG0596	Alpha beta hydrolase
OIO64_13550	COG0583	DNA-binding transcription factor activity
OIO64_13555	COG1335	isochorismatase
OIO64_13595	COG2879	small protein
OIO64_13600	COG1966	Carbon starvation protein
OIO64_13620	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OIO64_13645	COG1067	ATP-dependent peptidase activity
OIO64_13650	COG0583	DNA-binding transcription factor activity
OIO64_13675	COG1686	Belongs to the peptidase S11 family
OIO64_13680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OIO64_13715	COG0616	signal peptide processing
OIO64_13720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIO64_13730	COG0573	inorganic phosphate transmembrane transporter activity
OIO64_13735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIO64_13740	COG1113	amino acid transport
OIO64_13745	COG3961	Belongs to the TPP enzyme family
OIO64_13750	COG1522	sequence-specific DNA binding
OIO64_13760	COG0076	glutamate decarboxylase activity
OIO64_13765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO64_13775	COG1309	transcriptional regulator
OIO64_13790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO64_13825	COG0352	thiamine-phosphate diphosphorylase activity
OIO64_13850	COG0612	Peptidase, M16
OIO64_13860	COG1823	symporter activity
OIO64_13865	COG0583	DNA-binding transcription factor activity
OIO64_13870	COG0477	Major facilitator Superfamily
OIO64_13895	COG0582	viral genome integration into host DNA
OIO64_14030	COG4695	Portal protein
OIO64_14230	COG1187	pseudouridine synthase activity
OIO64_14245	COG1686	Belongs to the peptidase S11 family
OIO64_14250	COG1252	NADH dehydrogenase
OIO64_14265	COG2070	2-Nitropropane dioxygenase
OIO64_14320	COG0556	nucleotide-excision repair
OIO64_14340	COG0436	Aminotransferase
OIO64_14350	COG0443	Heat shock 70 kDa protein
OIO64_14380	COG4221	oxidoreductase activity
OIO64_14390	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OIO64_14395	COG1381	Involved in DNA repair and RecF pathway recombination
OIO64_14405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIO64_14420	COG0681	Belongs to the peptidase S26 family
OIO64_14430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIO64_14440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO64_14460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIO64_14465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIO64_14470	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OIO64_14480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIO64_14485	COG4208	sulfate ABC transporter
OIO64_14490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OIO64_14495	COG0583	DNA-binding transcription factor activity
OIO64_14500	COG4625	pathogenesis
OIO64_14515	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OIO64_14530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OIO64_14540	COG1056	cytidyltransferase-related domain
OIO64_14540	COG1051	belongs to the nudix hydrolase family
OIO64_14545	COG1024	Enoyl-CoA hydratase
OIO64_14560	COG2814	Major facilitator Superfamily
OIO64_14565	COG0047	phosphoribosylformylglycinamidine synthase activity
OIO64_14565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIO64_14585	COG1473	amidohydrolase
OIO64_14590	COG0824	Thioesterase
OIO64_14610	COG0823	Involved in the tonB-independent uptake of proteins
OIO64_14630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO64_14665	COG0628	permease
OIO64_14675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIO64_14680	COG0596	Alpha beta hydrolase
OIO64_14685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIO64_14685	COG0616	signal peptide processing
OIO64_14695	COG0658	competence protein
OIO64_14695	COG2333	competence protein COMEC
OIO64_14700	COG1136	(ABC) transporter
OIO64_14705	COG4591	ABC-type transport system involved in lipoprotein release permease component
OIO64_14740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO64_14760	COG0463	Glycosyl transferase, family 2
OIO64_14790	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO64_14795	COG1280	lysine exporter protein (LysE YggA)
OIO64_14800	COG2267	carboxylic ester hydrolase activity
OIO64_14810	COG0019	diaminopimelate decarboxylase activity
OIO64_14820	COG1113	amino acid transport
OIO64_14835	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OIO64_14845	COG3339	Conserved Protein
OIO64_14850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIO64_14855	COG0243	molybdopterin cofactor binding
OIO64_14860	COG1929	Belongs to the glycerate kinase type-1 family
OIO64_14875	COG0778	Nitroreductase
OIO64_14900	COG3811	Belongs to the UPF0386 family
OIO64_14925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO64_14940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIO64_14960	COG0741	lytic transglycosylase activity
OIO64_14980	COG0584	glycerophosphoryl diester phosphodiesterase
OIO64_14985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO64_15010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO64_15015	COG1597	lipid kinase activity
OIO64_15030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIO64_15035	COG0477	Major facilitator Superfamily
OIO64_15085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIO64_15090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO64_15115	COG0505	Belongs to the CarA family
OIO64_15135	COG0589	response to stress
OIO64_15150	COG2843	Capsule synthesis protein
OIO64_15170	COG2321	neutral zinc metallopeptidase
OIO64_15175	COG2354	Protein conserved in bacteria
OIO64_15195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO64_15220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIO64_15225	COG1053	succinate dehydrogenase
OIO64_15230	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OIO64_15235	COG2009	succinate dehydrogenase
OIO64_15270	COG2921	Belongs to the UPF0250 family
OIO64_15275	COG0321	lipoyl(octanoyl) transferase activity
OIO64_15290	COG0531	amino acid
OIO64_15300	COG1733	regulation of RNA biosynthetic process
OIO64_15305	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIO64_15310	COG1648	precorrin-2 dehydrogenase activity
OIO64_15310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIO64_15325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OIO64_15360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO64_15370	COG1538	Outer membrane efflux protein
OIO64_15375	COG0393	Putative heavy-metal-binding
OIO64_15380	COG0393	Putative heavy-metal-binding
OIO64_15390	COG1028	Short-chain dehydrogenase reductase Sdr
OIO64_15400	COG0525	valine-tRNA ligase activity
OIO64_15420	COG0583	DNA-binding transcription factor activity
OIO64_15425	COG0004	ammonium transporteR
OIO64_15440	COG0642	Histidine kinase
OIO64_15445	COG0745	RESPONSE REGULATOR receiver
OIO64_15450	COG2194	sulfuric ester hydrolase activity
OIO64_15470	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO64_15485	COG2315	Protein conserved in bacteria
OIO64_15490	COG0142	geranyltranstransferase activity
OIO64_15495	COG2828	Protein conserved in bacteria
OIO64_15500	COG1113	amino acid transport
OIO64_15545	COG2207	Transcriptional regulator
OIO64_15570	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO64_15580	COG0560	Phosphoserine phosphatase
OIO64_15590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO64_15600	COG1530	ribonuclease E activity
OIO64_15605	COG0424	maF-like protein
OIO64_15610	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OIO64_15615	COG1792	Involved in formation and maintenance of cell shape
OIO64_15620	COG1077	Cell shape determining protein MreB Mrl
OIO64_15625	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO64_15635	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO64_15660	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OIO64_15665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO64_15670	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO64_15675	COG1115	amino acid carrier protein
OIO64_15695	COG2814	Major facilitator Superfamily
OIO64_15700	COG1289	transmembrane transporter activity
OIO64_15710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OIO64_15760	COG1376	ErfK ybiS ycfS ynhG family protein
OIO64_15765	COG2832	Protein of unknown function (DUF454)
OIO64_15775	COG5510	response to toxic substance
OIO64_15800	COG0840	transmembrane signaling receptor activity
OIO64_15840	COG3422	double-strand break repair
OIO64_15845	COG2824	Alkylphosphonate utilization operon protein PhnA
OIO64_15850	COG3189	MarR family transcriptional regulator
OIO64_15860	COG0354	folic acid binding
OIO64_15865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO64_15875	COG0679	Auxin Efflux Carrier
OIO64_15880	COG1902	pentaerythritol trinitrate reductase activity
OIO64_15885	COG4772	TonB-dependent receptor
OIO64_15890	COG2094	Belongs to the DNA glycosylase MPG family
OIO64_15915	COG1217	gtp-binding protein TYPA
OIO64_15920	COG2233	PERMEase
OIO64_15930	COG0833	amino acid
OIO64_15935	COG1690	Belongs to the RtcB family
OIO64_15945	COG2885	chlorophyll binding
OIO64_15945	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OIO64_15955	COG0183	Belongs to the thiolase family
OIO64_15975	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO64_15995	COG2207	Transcriptional regulator
OIO64_16000	COG0183	Belongs to the thiolase family
OIO64_16030	COG1272	protein, Hemolysin III
OIO64_16035	COG0477	Major facilitator Superfamily
OIO64_16050	COG0450	alkyl hydroperoxide reductase
OIO64_16070	COG0285	dihydrofolate synthase activity
OIO64_16120	COG2096	Adenosyltransferase
OIO64_16125	COG0584	glycerophosphoryl diester phosphodiesterase
OIO64_16140	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OIO64_16145	COG0745	RESPONSE REGULATOR receiver
OIO64_16150	COG2205	protein histidine kinase activity
OIO64_16160	COG1960	acyl-CoA dehydrogenase activity
OIO64_16165	COG1960	acyl-CoA dehydrogenase activity
OIO64_16230	COG0438	transferase activity, transferring glycosyl groups
OIO64_16235	COG0463	Glycosyl transferase, family 2
OIO64_16240	COG0726	polysaccharide deacetylase
OIO64_16260	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIO64_16265	COG2205	protein histidine kinase activity
OIO64_16295	COG1862	Preprotein translocase
OIO64_16305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIO64_16310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIO64_16320	COG3781	membrane
OIO64_16325	COG0613	PHP domain protein
OIO64_16335	COG2350	Protein conserved in bacteria
OIO64_16365	COG1607	acyl-coa hydrolase
OIO64_16425	COG2199	diguanylate cyclase activity
OIO64_16435	COG1408	metallophosphoesterase
OIO64_16440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO64_16450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIO64_16470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIO64_16475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIO64_16480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OIO64_16490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIO64_16500	COG2969	positive regulation of protein catabolic process
OIO64_16520	COG1960	acyl-CoA dehydrogenase activity
OIO64_16525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO64_16540	COG1309	transcriptional regulator
OIO64_16545	COG1960	acyl-CoA dehydrogenase activity
OIO64_16590	COG1183	phosphatidylcholine synthase activity
OIO64_16595	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OIO64_16625	COG0741	lytic transglycosylase activity
OIO64_16625	COG0739	heme binding
OIO64_16625	COG1196	nuclear chromosome segregation
OIO64_16635	COG1702	phosphate starvation-inducible protein PhoH
OIO64_16670	COG1295	ribonuclease BN
OIO64_16675	COG0697	spore germination
OIO64_16680	COG2169	Transcriptional regulator
OIO64_16685	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO64_16730	COG0557	exoribonuclease II activity
OIO64_16735	COG0339	signal peptide processing
OIO64_16740	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OIO64_16770	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OIO64_16775	COG1960	acyl-CoA dehydrogenase activity
OIO64_16940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO64_16940	COG1017	nitric oxide dioxygenase activity
OIO64_16945	COG1959	2 iron, 2 sulfur cluster binding
OIO64_16960	COG1301	dicarboxylic acid transport
OIO64_16965	COG1946	Acyl-CoA thioesterase
OIO64_16985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIO64_16990	COG1040	competence protein
OIO64_16995	COG0494	nUDIX hydrolase
OIO64_17005	COG0598	Magnesium transport protein CorA
OIO64_17015	COG2854	intermembrane phospholipid transfer
OIO64_17025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIO64_17030	COG1127	ABC transporter
OIO64_17040	COG0513	Belongs to the DEAD box helicase family
OIO64_17060	COG0408	coproporphyrinogen oxidase activity
OIO64_17075	COG1960	acyl-CoA dehydrogenase activity
OIO64_17085	COG1983	PspC domain protein
OIO64_17090	COG0517	IMP dehydrogenase activity
OIO64_17115	COG0752	glycyl-tRNA synthetase alpha subunit
OIO64_17140	COG0583	DNA-binding transcription factor activity
OIO64_17180	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_17190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO64_17195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO64_17200	COG0833	amino acid
OIO64_17230	COG1192	Involved in chromosome partitioning
OIO64_17235	COG0628	permease
OIO64_17245	COG1289	transmembrane transporter activity
OIO64_17260	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO64_17265	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OIO64_17275	COG0277	FAD linked oxidase domain protein
OIO64_17280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIO64_17305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIO64_17310	COG5380	lipid catabolic process
OIO64_17330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIO64_17385	COG0194	GDP metabolic process
OIO64_17400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO64_17420	COG3307	-O-antigen
OIO64_17435	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OIO64_17440	COG1704	LemA family
OIO64_17450	COG0493	'glutamate synthase
OIO64_17455	COG0070	glutamate synthase
OIO64_17455	COG0069	glutamate synthase activity
OIO64_17455	COG0067	glutamate synthase
OIO64_17505	COG2226	methyltransferase
OIO64_17520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIO64_17525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIO64_17570	COG0833	amino acid
OIO64_17635	COG0488	(ABC) transporter
OIO64_17640	COG2873	o-acetylhomoserine
OIO64_17645	COG4221	oxidoreductase activity
OIO64_17650	COG0659	secondary active sulfate transmembrane transporter activity
OIO64_17675	COG0427	acetyl-CoA hydrolase
OIO64_17705	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIO64_17725	COG1132	(ABC) transporter
OIO64_17740	COG2329	Antibiotic biosynthesis monooxygenase
OIO64_17755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OIO64_17820	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO64_17825	COG1733	regulation of RNA biosynthetic process
OIO64_17860	COG0667	Aldo Keto reductase
OIO64_17880	COG1309	transcriptional regulator
OIO64_17895	COG0583	DNA-binding transcription factor activity
OIO64_17900	COG2814	Major facilitator Superfamily
OIO64_17935	COG1335	isochorismatase
OIO64_17945	COG1012	belongs to the aldehyde dehydrogenase family
OIO64_17950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO64_17960	COG1113	amino acid transport
OIO64_17970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO64_18010	COG2814	Major facilitator Superfamily
OIO64_18020	COG0352	thiamine-phosphate diphosphorylase activity
OIO64_18020	COG0351	phosphomethylpyrimidine kinase
OIO64_18020	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO64_18040	COG1309	transcriptional regulator
OIO64_18045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIO64_18065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO64_18075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO64_18080	COG3162	membrane
OIO64_18085	COG0784	Response regulator, receiver
OIO64_18085	COG2205	protein histidine kinase activity
OIO64_18085	COG2198	Histidine kinase
OIO64_18110	COG1522	sequence-specific DNA binding
OIO64_18115	COG1335	isochorismatase
OIO64_18120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO64_18130	COG0668	transmembrane transport
OIO64_18135	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO64_18140	COG1519	Transferase
OIO64_18145	COG1902	pentaerythritol trinitrate reductase activity
OIO64_18170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OIO64_18195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO64_18195	COG0426	domain, Protein
OIO64_18200	COG4774	siderophore transport
OIO64_18205	COG2119	membrane
OIO64_18215	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO64_18225	COG4942	peptidase
OIO64_18240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIO64_18250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIO64_18270	COG0189	ligase activity
OIO64_18290	COG0708	Exodeoxyribonuclease III
OIO64_18295	COG1393	Belongs to the ArsC family
OIO64_18310	COG3706	GGDEF domain
OIO64_18345	COG2351	hydroxyisourate hydrolase activity
OIO64_18350	COG2233	PERMEase
OIO64_18360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO64_18370	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OIO64_18380	COG3150	esterase
OIO64_18405	COG2918	glutathione biosynthetic process
OIO64_18420	COG2733	membrane
OIO64_18425	COG0436	Aminotransferase
OIO64_18430	COG0534	Mate efflux family protein
OIO64_18515	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OIO64_18520	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OIO64_18530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIO64_18555	COG1280	lysine exporter protein (LysE YggA)
OIO64_18575	COG0010	Belongs to the arginase family
OIO64_18605	COG2188	Transcriptional regulator
OIO64_18615	COG0523	cobalamin synthesis protein
OIO64_18625	COG1113	amino acid transport
OIO64_18635	COG0625	glutathione transferase activity
OIO64_18655	COG1683	Conserved Protein
OIO64_18660	COG0534	Mate efflux family protein
OIO64_18665	COG0385	Bile acid
OIO64_18670	COG1335	isochorismatase
OIO64_18675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO64_18695	COG2116	formate transmembrane transporter activity
OIO64_18700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OIO64_18715	COG3188	usher protein
OIO64_18720	COG3121	Chaperone
OIO64_18730	COG2983	Belongs to the UPF0260 family
OIO64_18750	COG1194	a g-specific adenine glycosylase
OIO64_18765	COG2818	Glycosylase
OIO64_18770	COG1064	alcohol dehydrogenase
OIO64_18775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO64_18790	COG0583	DNA-binding transcription factor activity
OIO64_18795	COG0656	L-ascorbic acid biosynthetic process
OIO64_18800	COG2814	Major facilitator Superfamily
OIO64_18835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO64_18850	COG2233	PERMEase
OIO64_18890	COG0733	neurotransmitter:sodium symporter activity
OIO64_18930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIO64_18935	COG0657	acetylesterase activity
OIO64_18955	COG0583	DNA-binding transcription factor activity
OIO64_18985	COG2951	lytic endotransglycosylase activity
OIO64_18990	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIO64_19005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIO64_19015	COG0671	phosphoesterase, PA-phosphatase related
OIO64_19020	COG0861	Integral membrane protein TerC family
OIO64_19030	COG0754	glutathionylspermidine amidase activity
OIO64_19040	COG0402	S-adenosylhomocysteine deaminase activity
OIO64_19055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO64_19060	COG1230	cation diffusion facilitator family transporter
OIO64_19075	COG0706	membrane insertase activity
OIO64_19125	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
OIO64_19130	COG0627	Serine hydrolase involved in the detoxification of formaldehyde