locus-tag	class	description
OIO47_00010	COG0592	DNA-directed DNA polymerase activity
OIO47_00020	COG0187	DNA topoisomerase II activity
OIO47_00030	COG0586	Pfam SNARE associated Golgi protein
OIO47_00035	COG0488	(ABC) transporter
OIO47_00060	COG0596	Alpha beta hydrolase
OIO47_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OIO47_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO47_00110	COG0733	neurotransmitter:sodium symporter activity
OIO47_00150	COG2233	PERMEase
OIO47_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO47_00200	COG2814	Major facilitator Superfamily
OIO47_00205	COG0656	L-ascorbic acid biosynthetic process
OIO47_00210	COG0583	DNA-binding transcription factor activity
OIO47_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO47_00230	COG1064	alcohol dehydrogenase
OIO47_00235	COG2818	Glycosylase
OIO47_00250	COG1194	a g-specific adenine glycosylase
OIO47_00270	COG2983	Belongs to the UPF0260 family
OIO47_00280	COG3121	Chaperone
OIO47_00285	COG3188	usher protein
OIO47_00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OIO47_00305	COG2116	formate transmembrane transporter activity
OIO47_00325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO47_00330	COG1335	isochorismatase
OIO47_00335	COG0385	Bile acid
OIO47_00340	COG0534	Mate efflux family protein
OIO47_00345	COG1683	Conserved Protein
OIO47_00365	COG0625	glutathione transferase activity
OIO47_00375	COG1113	amino acid transport
OIO47_00385	COG0523	cobalamin synthesis protein
OIO47_00395	COG2188	Transcriptional regulator
OIO47_00425	COG0010	Belongs to the arginase family
OIO47_00445	COG1280	lysine exporter protein (LysE YggA)
OIO47_00470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIO47_00480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OIO47_00485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OIO47_00570	COG0534	Mate efflux family protein
OIO47_00575	COG0436	Aminotransferase
OIO47_00580	COG2733	membrane
OIO47_00595	COG2918	glutathione biosynthetic process
OIO47_00620	COG3150	esterase
OIO47_00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OIO47_00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO47_00650	COG2233	PERMEase
OIO47_00655	COG2351	hydroxyisourate hydrolase activity
OIO47_00690	COG3706	GGDEF domain
OIO47_00705	COG1393	Belongs to the ArsC family
OIO47_00710	COG0708	Exodeoxyribonuclease III
OIO47_00730	COG0189	ligase activity
OIO47_00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIO47_00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIO47_00775	COG4942	peptidase
OIO47_00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO47_00795	COG2119	membrane
OIO47_00800	COG4774	siderophore transport
OIO47_00805	COG0426	domain, Protein
OIO47_00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO47_00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OIO47_00855	COG1902	pentaerythritol trinitrate reductase activity
OIO47_00860	COG1519	Transferase
OIO47_00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO47_00870	COG0668	transmembrane transport
OIO47_00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO47_00885	COG1335	isochorismatase
OIO47_00890	COG1522	sequence-specific DNA binding
OIO47_00915	COG0784	Response regulator, receiver
OIO47_00915	COG2198	Histidine kinase
OIO47_00915	COG2205	protein histidine kinase activity
OIO47_00920	COG3162	membrane
OIO47_00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO47_00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO47_00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIO47_00960	COG1309	transcriptional regulator
OIO47_00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO47_00980	COG0352	thiamine-phosphate diphosphorylase activity
OIO47_00980	COG0351	phosphomethylpyrimidine kinase
OIO47_00990	COG2814	Major facilitator Superfamily
OIO47_01030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO47_01040	COG1113	amino acid transport
OIO47_01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO47_01055	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_01065	COG1335	isochorismatase
OIO47_01100	COG2814	Major facilitator Superfamily
OIO47_01105	COG0583	DNA-binding transcription factor activity
OIO47_01120	COG1309	transcriptional regulator
OIO47_01140	COG0667	Aldo Keto reductase
OIO47_01175	COG1733	regulation of RNA biosynthetic process
OIO47_01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO47_01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OIO47_01260	COG2329	Antibiotic biosynthesis monooxygenase
OIO47_01275	COG1132	(ABC) transporter
OIO47_01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIO47_01325	COG0427	acetyl-CoA hydrolase
OIO47_01350	COG0659	secondary active sulfate transmembrane transporter activity
OIO47_01355	COG4221	oxidoreductase activity
OIO47_01360	COG2873	o-acetylhomoserine
OIO47_01365	COG0488	(ABC) transporter
OIO47_01430	COG0833	amino acid
OIO47_01475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIO47_01480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIO47_01495	COG2226	methyltransferase
OIO47_01545	COG0070	glutamate synthase
OIO47_01545	COG0069	glutamate synthase activity
OIO47_01545	COG0067	glutamate synthase
OIO47_01550	COG0493	'glutamate synthase
OIO47_01560	COG1704	LemA family
OIO47_01565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OIO47_01580	COG3307	-O-antigen
OIO47_01600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO47_01615	COG0194	GDP metabolic process
OIO47_01670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIO47_01690	COG5380	lipid catabolic process
OIO47_01695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIO47_01720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIO47_01725	COG0277	FAD linked oxidase domain protein
OIO47_01735	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OIO47_01740	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO47_01755	COG1289	transmembrane transporter activity
OIO47_01765	COG0628	permease
OIO47_01770	COG1192	Involved in chromosome partitioning
OIO47_01800	COG0833	amino acid
OIO47_01805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO47_01810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO47_01820	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_01860	COG0583	DNA-binding transcription factor activity
OIO47_01885	COG0752	glycyl-tRNA synthetase alpha subunit
OIO47_01910	COG0517	IMP dehydrogenase activity
OIO47_01915	COG1983	PspC domain protein
OIO47_01925	COG1960	acyl-CoA dehydrogenase activity
OIO47_01940	COG0408	coproporphyrinogen oxidase activity
OIO47_01960	COG0513	Belongs to the DEAD box helicase family
OIO47_01970	COG1127	ABC transporter
OIO47_01975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIO47_01985	COG2854	intermembrane phospholipid transfer
OIO47_01995	COG0598	Magnesium transport protein CorA
OIO47_02005	COG0494	nUDIX hydrolase
OIO47_02010	COG1040	competence protein
OIO47_02015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIO47_02035	COG1946	Acyl-CoA thioesterase
OIO47_02040	COG1301	dicarboxylic acid transport
OIO47_02055	COG1959	2 iron, 2 sulfur cluster binding
OIO47_02060	COG1017	nitric oxide dioxygenase activity
OIO47_02060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO47_02225	COG1960	acyl-CoA dehydrogenase activity
OIO47_02230	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OIO47_02260	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OIO47_02265	COG0339	signal peptide processing
OIO47_02270	COG0557	exoribonuclease II activity
OIO47_02315	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO47_02320	COG2169	Transcriptional regulator
OIO47_02325	COG0697	spore germination
OIO47_02330	COG1295	ribonuclease BN
OIO47_02365	COG1702	phosphate starvation-inducible protein PhoH
OIO47_02375	COG0741	lytic transglycosylase activity
OIO47_02375	COG1196	nuclear chromosome segregation
OIO47_02375	COG0739	heme binding
OIO47_02405	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OIO47_02410	COG1183	phosphatidylcholine synthase activity
OIO47_02455	COG1960	acyl-CoA dehydrogenase activity
OIO47_02460	COG1309	transcriptional regulator
OIO47_02475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO47_02480	COG1960	acyl-CoA dehydrogenase activity
OIO47_02500	COG2969	positive regulation of protein catabolic process
OIO47_02510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIO47_02520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OIO47_02525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIO47_02530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIO47_02550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIO47_02560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO47_02565	COG1408	metallophosphoesterase
OIO47_02575	COG2199	diguanylate cyclase activity
OIO47_02635	COG1607	acyl-coa hydrolase
OIO47_02665	COG2350	Protein conserved in bacteria
OIO47_02675	COG0613	PHP domain protein
OIO47_02680	COG3781	membrane
OIO47_02690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIO47_02695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIO47_02705	COG1862	Preprotein translocase
OIO47_02735	COG2205	protein histidine kinase activity
OIO47_02740	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIO47_02760	COG0726	polysaccharide deacetylase
OIO47_02765	COG0463	Glycosyl transferase, family 2
OIO47_02770	COG0438	transferase activity, transferring glycosyl groups
OIO47_02835	COG1960	acyl-CoA dehydrogenase activity
OIO47_02840	COG1960	acyl-CoA dehydrogenase activity
OIO47_02850	COG2205	protein histidine kinase activity
OIO47_02855	COG0745	RESPONSE REGULATOR receiver
OIO47_02860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OIO47_02875	COG0584	glycerophosphoryl diester phosphodiesterase
OIO47_02880	COG2096	Adenosyltransferase
OIO47_02930	COG0285	dihydrofolate synthase activity
OIO47_02950	COG0450	alkyl hydroperoxide reductase
OIO47_02965	COG0477	Major facilitator Superfamily
OIO47_02970	COG1272	protein, Hemolysin III
OIO47_03000	COG0183	Belongs to the thiolase family
OIO47_03005	COG2207	Transcriptional regulator
OIO47_03025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO47_03045	COG0183	Belongs to the thiolase family
OIO47_03055	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OIO47_03055	COG2885	chlorophyll binding
OIO47_03065	COG1690	Belongs to the RtcB family
OIO47_03070	COG0833	amino acid
OIO47_03080	COG2233	PERMEase
OIO47_03085	COG1217	gtp-binding protein TYPA
OIO47_03110	COG2094	Belongs to the DNA glycosylase MPG family
OIO47_03115	COG4772	TonB-dependent receptor
OIO47_03120	COG1902	pentaerythritol trinitrate reductase activity
OIO47_03135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO47_03140	COG0354	folic acid binding
OIO47_03150	COG3189	MarR family transcriptional regulator
OIO47_03155	COG2824	Alkylphosphonate utilization operon protein PhnA
OIO47_03160	COG3422	double-strand break repair
OIO47_03200	COG0840	transmembrane signaling receptor activity
OIO47_03225	COG5510	response to toxic substance
OIO47_03235	COG2832	Protein of unknown function (DUF454)
OIO47_03240	COG1376	ErfK ybiS ycfS ynhG family protein
OIO47_03290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OIO47_03300	COG1289	transmembrane transporter activity
OIO47_03305	COG2814	Major facilitator Superfamily
OIO47_03325	COG1115	amino acid carrier protein
OIO47_03330	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO47_03335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO47_03340	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OIO47_03365	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO47_03375	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO47_03380	COG1077	Cell shape determining protein MreB Mrl
OIO47_03385	COG1792	Involved in formation and maintenance of cell shape
OIO47_03390	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OIO47_03395	COG0424	maF-like protein
OIO47_03400	COG1530	ribonuclease E activity
OIO47_03410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO47_03420	COG0560	Phosphoserine phosphatase
OIO47_03430	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO47_03455	COG2207	Transcriptional regulator
OIO47_03500	COG1113	amino acid transport
OIO47_03505	COG2828	Protein conserved in bacteria
OIO47_03510	COG0142	geranyltranstransferase activity
OIO47_03515	COG2315	Protein conserved in bacteria
OIO47_03530	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO47_03550	COG2194	sulfuric ester hydrolase activity
OIO47_03555	COG0745	RESPONSE REGULATOR receiver
OIO47_03560	COG0642	Histidine kinase
OIO47_03575	COG0004	ammonium transporteR
OIO47_03580	COG0583	DNA-binding transcription factor activity
OIO47_03600	COG0525	valine-tRNA ligase activity
OIO47_03610	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_03620	COG0393	Putative heavy-metal-binding
OIO47_03625	COG0393	Putative heavy-metal-binding
OIO47_03630	COG1538	Outer membrane efflux protein
OIO47_03640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO47_03675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OIO47_03690	COG1648	precorrin-2 dehydrogenase activity
OIO47_03690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIO47_03695	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIO47_03700	COG1733	regulation of RNA biosynthetic process
OIO47_03710	COG0531	amino acid
OIO47_03725	COG0321	lipoyl(octanoyl) transferase activity
OIO47_03730	COG2921	Belongs to the UPF0250 family
OIO47_03765	COG2009	succinate dehydrogenase
OIO47_03770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OIO47_03775	COG1053	succinate dehydrogenase
OIO47_03780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIO47_03805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO47_03825	COG2354	Protein conserved in bacteria
OIO47_03830	COG2321	neutral zinc metallopeptidase
OIO47_03850	COG2843	Capsule synthesis protein
OIO47_03865	COG0589	response to stress
OIO47_03885	COG0505	Belongs to the CarA family
OIO47_03910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO47_03915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIO47_03965	COG0477	Major facilitator Superfamily
OIO47_03970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIO47_03985	COG1597	lipid kinase activity
OIO47_03990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO47_04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO47_04020	COG0584	glycerophosphoryl diester phosphodiesterase
OIO47_04040	COG0741	lytic transglycosylase activity
OIO47_04060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIO47_04075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO47_04100	COG3811	Belongs to the UPF0386 family
OIO47_04125	COG0778	Nitroreductase
OIO47_04140	COG1929	Belongs to the glycerate kinase type-1 family
OIO47_04145	COG0243	molybdopterin cofactor binding
OIO47_04150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIO47_04155	COG3339	Conserved Protein
OIO47_04165	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OIO47_04180	COG1113	amino acid transport
OIO47_04190	COG0019	diaminopimelate decarboxylase activity
OIO47_04200	COG2267	carboxylic ester hydrolase activity
OIO47_04205	COG1280	lysine exporter protein (LysE YggA)
OIO47_04210	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO47_04240	COG0463	Glycosyl transferase, family 2
OIO47_04260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO47_04295	COG4591	ABC-type transport system involved in lipoprotein release permease component
OIO47_04300	COG1136	(ABC) transporter
OIO47_04305	COG0658	competence protein
OIO47_04305	COG2333	competence protein COMEC
OIO47_04315	COG0616	signal peptide processing
OIO47_04315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIO47_04320	COG0596	Alpha beta hydrolase
OIO47_04325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIO47_04335	COG0628	permease
OIO47_04370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO47_04390	COG0823	Involved in the tonB-independent uptake of proteins
OIO47_04410	COG0824	Thioesterase
OIO47_04415	COG1473	amidohydrolase
OIO47_04435	COG0047	phosphoribosylformylglycinamidine synthase activity
OIO47_04435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIO47_04440	COG2814	Major facilitator Superfamily
OIO47_04455	COG1024	Enoyl-CoA hydratase
OIO47_04460	COG1051	belongs to the nudix hydrolase family
OIO47_04460	COG1056	cytidyltransferase-related domain
OIO47_04470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OIO47_04485	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OIO47_04500	COG4625	pathogenesis
OIO47_04505	COG0583	DNA-binding transcription factor activity
OIO47_04510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OIO47_04515	COG4208	sulfate ABC transporter
OIO47_04520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIO47_04530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OIO47_04535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIO47_04540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIO47_04560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO47_04570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIO47_04580	COG0681	Belongs to the peptidase S26 family
OIO47_04595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIO47_04605	COG1381	Involved in DNA repair and RecF pathway recombination
OIO47_04610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OIO47_04620	COG4221	oxidoreductase activity
OIO47_04650	COG0443	Heat shock 70 kDa protein
OIO47_04660	COG0436	Aminotransferase
OIO47_04680	COG0556	nucleotide-excision repair
OIO47_04735	COG2070	2-Nitropropane dioxygenase
OIO47_04750	COG1252	NADH dehydrogenase
OIO47_04755	COG1686	Belongs to the peptidase S11 family
OIO47_04770	COG1187	pseudouridine synthase activity
OIO47_04965	COG4695	Portal protein
OIO47_05105	COG0582	viral genome integration into host DNA
OIO47_05130	COG0477	Major facilitator Superfamily
OIO47_05135	COG0583	DNA-binding transcription factor activity
OIO47_05140	COG1823	symporter activity
OIO47_05150	COG0612	Peptidase, M16
OIO47_05175	COG0352	thiamine-phosphate diphosphorylase activity
OIO47_05210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO47_05225	COG1309	transcriptional regulator
OIO47_05235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO47_05240	COG0076	glutamate decarboxylase activity
OIO47_05250	COG1522	sequence-specific DNA binding
OIO47_05255	COG3961	Belongs to the TPP enzyme family
OIO47_05260	COG1113	amino acid transport
OIO47_05265	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIO47_05270	COG0573	inorganic phosphate transmembrane transporter activity
OIO47_05280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIO47_05285	COG0616	signal peptide processing
OIO47_05320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OIO47_05325	COG1686	Belongs to the peptidase S11 family
OIO47_05350	COG0583	DNA-binding transcription factor activity
OIO47_05355	COG1067	ATP-dependent peptidase activity
OIO47_05380	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OIO47_05405	COG1966	Carbon starvation protein
OIO47_05410	COG2879	small protein
OIO47_05450	COG1335	isochorismatase
OIO47_05455	COG0583	DNA-binding transcription factor activity
OIO47_05470	COG0596	Alpha beta hydrolase
OIO47_05480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO47_05490	COG2130	NADP-dependent
OIO47_05520	COG1741	Belongs to the pirin family
OIO47_05530	COG2964	Protein conserved in bacteria
OIO47_05545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO47_05555	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO47_05560	COG4605	iron ion homeostasis
OIO47_05565	COG4604	ABC transporter, ATP-binding protein
OIO47_05570	COG4607	ABC-type enterochelin transport system periplasmic component
OIO47_05575	COG4774	siderophore transport
OIO47_05585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO47_05590	COG1021	2,3-dihydroxybenzoate-AMP ligase
OIO47_05595	COG1535	isochorismatase
OIO47_05595	COG3433	isochorismatase activity
OIO47_05610	COG1132	(ABC) transporter
OIO47_05615	COG1132	(ABC) transporter
OIO47_05620	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OIO47_05625	COG2977	Belongs to the P-Pant transferase superfamily
OIO47_05645	COG3739	integral membrane protein
OIO47_05665	COG0302	gtp cyclohydrolase
OIO47_05675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIO47_05705	COG0308	aminopeptidase N
OIO47_05710	COG0512	Glutamine amidotransferase of anthranilate synthase
OIO47_05725	COG0174	glutamine synthetase
OIO47_05735	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OIO47_05770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIO47_05775	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIO47_05780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO47_05800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO47_05805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIO47_05810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIO47_05825	COG1960	acyl-CoA dehydrogenase activity
OIO47_05830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO47_05835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO47_05845	COG2223	nitrite transmembrane transporter activity
OIO47_05865	COG0024	Methionine aminopeptidase
OIO47_05870	COG0052	Belongs to the universal ribosomal protein uS2 family
OIO47_05885	COG2207	Transcriptional regulator
OIO47_05910	COG2951	lytic endotransglycosylase activity
OIO47_05915	COG0772	Belongs to the SEDS family
OIO47_05930	COG0842	Transport permease protein
OIO47_05935	COG1131	(ABC) transporter
OIO47_05980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO47_05995	COG4215	(ABC) transporter
OIO47_06000	COG4160	amino acid transport
OIO47_06005	COG4598	ABC transporter
OIO47_06015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO47_06020	COG0826	peptidase U32
OIO47_06025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO47_06040	COG1720	tRNA m6t6A37 methyltransferase activity
OIO47_06050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OIO47_06065	COG0642	Histidine kinase
OIO47_06075	COG0494	nUDIX hydrolase
OIO47_06085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIO47_06090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIO47_06095	COG3139	Protein of unknown function (DUF1315)
OIO47_06105	COG1301	dicarboxylic acid transport
OIO47_06110	COG1960	acyl-CoA dehydrogenase activity
OIO47_06115	COG2819	hydrolase of the alpha beta superfamily
OIO47_06125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIO47_06135	COG2195	Cleaves the N-terminal amino acid of tripeptides
OIO47_06155	COG1690	Belongs to the RtcB family
OIO47_06160	COG1234	tRNA 3'-trailer cleavage
OIO47_06165	COG4650	regulator
OIO47_06195	COG2363	Small membrane protein
OIO47_06220	COG0513	Belongs to the DEAD box helicase family
OIO47_06230	COG0778	Nitroreductase
OIO47_06260	COG1286	toxin biosynthetic process
OIO47_06285	COG4783	chaperone-mediated protein folding
OIO47_06290	COG1610	YqeY-like protein
OIO47_06320	COG0515	serine threonine protein kinase
OIO47_06320	COG2815	serine threonine protein kinase
OIO47_06390	COG3111	PFAM Bacterial OB fold (BOF) protein
OIO47_06415	COG3243	poly(R)-hydroxyalkanoic acid synthase
OIO47_06420	COG0786	glutamate:sodium symporter activity
OIO47_06430	COG2186	Transcriptional regulator
OIO47_06440	COG0477	Major facilitator Superfamily
OIO47_06470	COG2995	paraquat-inducible protein a
OIO47_06475	COG3008	intermembrane lipid transfer
OIO47_06475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIO47_06485	COG1794	racemase activity, acting on amino acids and derivatives
OIO47_06515	COG1301	dicarboxylic acid transport
OIO47_06525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO47_06530	COG2011	ABC-type metal ion transport system permease component
OIO47_06535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO47_06540	COG1464	Belongs to the NlpA lipoprotein family
OIO47_06545	COG0151	Belongs to the GarS family
OIO47_06550	COG0138	bifunctional purine biosynthesis protein purh
OIO47_06555	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OIO47_06585	COG2308	Evidence 4 Homologs of previously reported genes of
OIO47_06595	COG1305	Transglutaminase-like
OIO47_06605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIO47_06610	COG0305	Participates in initiation and elongation during chromosome replication
OIO47_06635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OIO47_06645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIO47_06650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIO47_06675	COG0726	polysaccharide deacetylase
OIO47_06675	COG1649	PFAM Uncharacterised BCR, COG1649
OIO47_06680	COG1215	transferase activity, transferring glycosyl groups
OIO47_06685	COG3658	cytochrome
OIO47_06695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO47_06710	COG0583	DNA-binding transcription factor activity
OIO47_06730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO47_06735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO47_06750	COG1960	acyl-CoA dehydrogenase activity
OIO47_06755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO47_06760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO47_06775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OIO47_06785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIO47_06790	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIO47_06805	COG0745	RESPONSE REGULATOR receiver
OIO47_06810	COG0174	glutamine synthetase
OIO47_06830	COG0729	surface antigen
OIO47_06855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO47_06860	COG2814	Major facilitator Superfamily
OIO47_06875	COG0583	DNA-binding transcription factor activity
OIO47_06890	COG1187	pseudouridine synthase activity
OIO47_06910	COG0802	atpase or kinase
OIO47_06915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIO47_06925	COG1923	regulation of RNA biosynthetic process
OIO47_06930	COG0697	spore germination
OIO47_06955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO47_06960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO47_06960	COG0519	Catalyzes the synthesis of GMP from XMP
OIO47_06965	COG4302	ethanolamine ammonia-lyase activity
OIO47_06970	COG4303	Ethanolamine ammonia lyase large subunit
OIO47_06975	COG0531	amino acid
OIO47_06995	COG1454	alcohol dehydrogenase
OIO47_07000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO47_07010	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OIO47_07030	COG0308	aminopeptidase N
OIO47_07050	COG1605	Chorismate mutase
OIO47_07070	COG1309	transcriptional regulator
OIO47_07080	COG0668	transmembrane transport
OIO47_07110	COG4773	Receptor
OIO47_07130	COG0488	(ABC) transporter
OIO47_07135	COG0589	response to stress
OIO47_07160	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIO47_07170	COG3135	benzoate transporter
OIO47_07175	COG1522	sequence-specific DNA binding
OIO47_07185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIO47_07190	COG0583	DNA-binding transcription factor activity
OIO47_07200	COG0183	Belongs to the thiolase family
OIO47_07210	COG2030	dehydratase
OIO47_07215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO47_07230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIO47_07240	COG0824	Thioesterase
OIO47_07245	COG1454	alcohol dehydrogenase
OIO47_07255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIO47_07275	COG0069	glutamate synthase activity
OIO47_07295	COG2814	Major facilitator Superfamily
OIO47_07310	COG0511	ligase activity, forming carbon-carbon bonds
OIO47_07330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO47_07330	COG1116	anion transmembrane transporter activity
OIO47_07335	COG0745	RESPONSE REGULATOR receiver
OIO47_07345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO47_07345	COG2146	nitrite reductase [NAD(P)H] activity
OIO47_07350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO47_07355	COG0243	molybdopterin cofactor binding
OIO47_07365	COG0243	molybdopterin cofactor binding
OIO47_07385	COG0315	cyclic pyranopterin monophosphate synthase activity
OIO47_07385	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIO47_07400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO47_07405	COG0697	spore germination
OIO47_07425	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OIO47_07430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO47_07485	COG2204	response regulator
OIO47_07490	COG3852	Histidine kinase
OIO47_07510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIO47_07515	COG0575	Belongs to the CDS family
OIO47_07530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO47_07550	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO47_07565	COG2137	regulation of response to DNA damage stimulus
OIO47_07575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OIO47_07580	COG1011	Hydrolase
OIO47_07605	COG1522	sequence-specific DNA binding
OIO47_07615	COG1113	amino acid transport
OIO47_07635	COG0659	secondary active sulfate transmembrane transporter activity
OIO47_07640	COG2135	peptidase activity
OIO47_07655	COG5001	Diguanylate cyclase
OIO47_07655	COG3300	MHYT domain
OIO47_07675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO47_07675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO47_07675	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIO47_07680	COG1105	Belongs to the carbohydrate kinase PfkB family
OIO47_07685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO47_07685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIO47_07715	COG0024	Methionine aminopeptidase
OIO47_07720	COG0583	DNA-binding transcription factor activity
OIO47_07730	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OIO47_07735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO47_07740	COG0517	IMP dehydrogenase activity
OIO47_07740	COG0516	GMP reductase activity
OIO47_07765	COG0552	protein localization to endoplasmic reticulum
OIO47_07775	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OIO47_07785	COG4890	Cyd operon protein YbgT
OIO47_07790	COG1294	oxidase, subunit
OIO47_07805	COG1585	Membrane protein implicated in regulation of membrane protease activity
OIO47_07815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIO47_07820	COG4774	siderophore transport
OIO47_07835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIO47_07840	COG0569	domain protein
OIO47_07845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO47_07875	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIO47_07880	COG0542	response to heat
OIO47_07890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO47_07905	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO47_07905	COG1902	pentaerythritol trinitrate reductase activity
OIO47_07950	COG2323	membrane
OIO47_07955	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OIO47_07965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO47_07970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO47_07975	COG0183	Belongs to the thiolase family
OIO47_07980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIO47_07985	COG0596	Alpha beta hydrolase
OIO47_07990	COG2271	Major facilitator Superfamily
OIO47_07995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO47_08000	COG3485	protocatechuate 3,4-dioxygenase
OIO47_08005	COG3485	protocatechuate 3,4-dioxygenase
OIO47_08010	COG0710	3-dehydroquinate dehydratase activity
OIO47_08015	COG3420	alginic acid biosynthetic process
OIO47_08020	COG3659	wide pore channel activity
OIO47_08025	COG4993	Dehydrogenase
OIO47_08035	COG2391	methyltransferase activity
OIO47_08050	COG1414	Transcriptional regulator
OIO47_08055	COG0583	DNA-binding transcription factor activity
OIO47_08060	COG1960	acyl-CoA dehydrogenase activity
OIO47_08085	COG2814	Major facilitator Superfamily
OIO47_08095	COG0154	amidase activity
OIO47_08115	COG4638	Rieske (2fe-2S)
OIO47_08125	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_08135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO47_08145	COG3733	amine oxidase
OIO47_08155	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_08165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO47_08170	COG0183	Belongs to the thiolase family
OIO47_08175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO47_08180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO47_08190	COG4829	muconolactone delta-isomerase
OIO47_08195	COG4948	Mandelate Racemase Muconate Lactonizing
OIO47_08200	COG0583	DNA-binding transcription factor activity
OIO47_08210	COG2186	Transcriptional regulator
OIO47_08230	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_08235	COG3231	kanamycin kinase activity
OIO47_08250	COG1960	acyl-CoA dehydrogenase activity
OIO47_08255	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_08260	COG3829	transcription factor binding
OIO47_08270	COG3162	membrane
OIO47_08285	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_08300	COG0753	catalase activity
OIO47_08325	COG1846	Transcriptional regulator
OIO47_08330	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO47_08330	COG1902	pentaerythritol trinitrate reductase activity
OIO47_08365	COG1309	transcriptional regulator
OIO47_08375	COG1335	isochorismatase
OIO47_08380	COG0583	DNA-binding transcription factor activity
OIO47_08390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO47_08390	COG0475	glutathione-regulated potassium exporter activity
OIO47_08400	COG1473	amidohydrolase
OIO47_08455	COG2188	Transcriptional regulator
OIO47_08470	COG0583	DNA-binding transcription factor activity
OIO47_08505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO47_08525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO47_08545	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_08560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO47_08565	COG2814	Major facilitator Superfamily
OIO47_08575	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO47_08585	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_08590	COG3384	dioxygenase
OIO47_08600	COG3971	2-oxopent-4-enoate hydratase activity
OIO47_08615	COG0477	Major facilitator Superfamily
OIO47_08620	COG1960	acyl-CoA dehydrogenase activity
OIO47_08625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO47_08630	COG1846	Transcriptional regulator
OIO47_08635	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_08640	COG0129	dihydroxy-acid dehydratase activity
OIO47_08650	COG0583	DNA-binding transcription factor activity
OIO47_08655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO47_08665	COG2084	Dehydrogenase
OIO47_08670	COG2207	Transcriptional regulator
OIO47_08685	COG1064	alcohol dehydrogenase
OIO47_08695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO47_08700	COG1120	ATPase activity
OIO47_08720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO47_08770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OIO47_08795	COG2814	Major facilitator Superfamily
OIO47_08800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO47_08800	COG3320	Male sterility
OIO47_08830	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_08840	COG2207	Transcriptional regulator
OIO47_08850	COG2205	protein histidine kinase activity
OIO47_08855	COG0745	RESPONSE REGULATOR receiver
OIO47_08860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO47_08865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO47_08890	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO47_08900	COG0753	catalase activity
OIO47_08920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO47_08980	COG1535	isochorismatase
OIO47_08980	COG3433	isochorismatase activity
OIO47_08985	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_08990	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OIO47_08995	COG4149	molybdate abc transporter
OIO47_09000	COG0725	ABC transporter, periplasmic molybdate-binding protein
OIO47_09010	COG4638	Rieske (2fe-2S)
OIO47_09015	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO47_09020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO47_09020	COG0543	2 iron, 2 sulfur cluster binding
OIO47_09035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO47_09045	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_09060	COG2207	Transcriptional regulator
OIO47_09065	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_09070	COG2610	gluconate transmembrane transporter activity
OIO47_09080	COG0583	DNA-binding transcription factor activity
OIO47_09095	COG2031	fatty acid transporter
OIO47_09100	COG0183	Belongs to the thiolase family
OIO47_09105	COG0583	DNA-binding transcription factor activity
OIO47_09110	COG0583	DNA-binding transcription factor activity
OIO47_09125	COG1027	Aspartate ammonia-lyase
OIO47_09135	COG0477	Major facilitator Superfamily
OIO47_09155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO47_09160	COG4521	taurine ABC transporter
OIO47_09175	COG2188	Transcriptional regulator
OIO47_09185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIO47_09190	COG1733	regulation of RNA biosynthetic process
OIO47_09195	COG2207	Transcriptional regulator
OIO47_09195	COG3708	Transcriptional regulator
OIO47_09210	COG0730	response to heat
OIO47_09225	COG3453	Protein conserved in bacteria
OIO47_09225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO47_09235	COG3781	membrane
OIO47_09240	COG1063	alcohol dehydrogenase
OIO47_09250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO47_09255	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO47_09260	COG0022	dehydrogenase e1 component
OIO47_09265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OIO47_09270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO47_09285	COG3706	GGDEF domain
OIO47_09300	COG0133	tryptophan synthase activity
OIO47_09310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO47_09345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIO47_09370	COG2226	methyltransferase
OIO47_09425	COG0842	Transport permease protein
OIO47_09430	COG0842	Transport permease protein
OIO47_09435	COG1131	(ABC) transporter
OIO47_09450	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO47_09475	COG0730	response to heat
OIO47_09480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO47_09495	COG0406	alpha-ribazole phosphatase activity
OIO47_09500	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIO47_09515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO47_09545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO47_09555	COG4264	IucA IucC family
OIO47_09560	COG4264	IucA IucC family
OIO47_09565	COG2814	Major facilitator Superfamily
OIO47_09580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIO47_09595	COG1960	acyl-CoA dehydrogenase activity
OIO47_09600	COG1960	acyl-CoA dehydrogenase activity
OIO47_09605	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO47_09610	COG2207	Transcriptional regulator
OIO47_09615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO47_09620	COG0776	regulation of translation
OIO47_09645	COG0822	iron-sulfur transferase activity
OIO47_09650	COG0316	Belongs to the HesB IscA family
OIO47_09680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO47_09700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO47_09705	COG0702	epimerase
OIO47_09740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIO47_09750	COG0339	signal peptide processing
OIO47_09760	COG4166	transmembrane transport
OIO47_09795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIO47_09800	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OIO47_09830	COG0776	regulation of translation
OIO47_09895	COG0084	hydrolase, TatD family'
OIO47_09915	COG1663	tetraacyldisaccharide 4'-kinase activity
OIO47_09920	COG1132	(ABC) transporter
OIO47_09930	COG0811	peptide transport
OIO47_09935	COG1475	DNA binding
OIO47_09940	COG1192	Involved in chromosome partitioning
OIO47_09950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIO47_09965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO47_09970	COG0191	fructose-bisphosphate aldolase activity
OIO47_09990	COG0424	maF-like protein
OIO47_09995	COG2850	peptidyl-arginine hydroxylation
OIO47_10005	COG0640	Transcriptional regulator
OIO47_10015	COG3619	membrane
OIO47_10020	COG3122	Protein conserved in bacteria
OIO47_10025	COG1132	(ABC) transporter
OIO47_10045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIO47_10050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO47_10060	COG0506	proline dehydrogenase activity
OIO47_10060	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO47_10060	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO47_10065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIO47_10080	COG3698	Phosphodiester glycosidase
OIO47_10090	COG2353	YceI-like domain
OIO47_10100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIO47_10145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIO47_10145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIO47_10170	COG3539	Fimbrial protein
OIO47_10175	COG3121	Chaperone
OIO47_10200	COG0697	spore germination
OIO47_10210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO47_10220	COG0583	DNA-binding transcription factor activity
OIO47_10240	COG1309	transcriptional regulator
OIO47_10255	COG1522	sequence-specific DNA binding
OIO47_10265	COG1126	abc transporter atp-binding protein
OIO47_10270	COG0765	amino acid transport
OIO47_10275	COG0765	amino acid transport
OIO47_10305	COG1464	Belongs to the NlpA lipoprotein family
OIO47_10315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO47_10320	COG2011	ABC-type metal ion transport system permease component
OIO47_10325	COG0012	GTP binding
OIO47_10350	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO47_10390	COG0386	Belongs to the glutathione peroxidase family
OIO47_10400	COG0436	Aminotransferase
OIO47_10405	COG1301	dicarboxylic acid transport
OIO47_10440	COG3634	alkyl hydroperoxide reductase activity
OIO47_10455	COG0583	DNA-binding transcription factor activity
OIO47_10460	COG0798	PFAM Bile acid sodium symporter
OIO47_10465	COG0640	Transcriptional regulator
OIO47_10480	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIO47_10490	COG0583	DNA-binding transcription factor activity
OIO47_10500	COG1953	Uracil, thiamine, allantoin
OIO47_10510	COG2175	clavaminate synthase activity
OIO47_10515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO47_10535	COG4521	taurine ABC transporter
OIO47_10545	COG0477	Major facilitator Superfamily
OIO47_10565	COG1271	oxidase subunit
OIO47_10570	COG1294	oxidase, subunit
OIO47_10580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO47_10600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OIO47_10620	COG3052	prosthetic group binding
OIO47_10625	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OIO47_10635	COG0583	DNA-binding transcription factor activity
OIO47_10645	COG2814	Major facilitator Superfamily
OIO47_10665	COG1346	cytolysis
OIO47_10675	COG0583	DNA-binding transcription factor activity
OIO47_10680	COG0625	glutathione transferase activity
OIO47_10685	COG0625	glutathione transferase activity
OIO47_10690	COG0583	DNA-binding transcription factor activity
OIO47_10695	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_10705	COG1045	serine acetyltransferase
OIO47_10710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO47_10715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIO47_10725	COG1280	lysine exporter protein (LysE YggA)
OIO47_10740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO47_10745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO47_10750	COG1126	abc transporter atp-binding protein
OIO47_10755	COG0765	amino acid transport
OIO47_10760	COG0765	amino acid transport
OIO47_10780	COG0784	Response regulator, receiver
OIO47_10780	COG2205	protein histidine kinase activity
OIO47_10800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIO47_10820	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_10870	COG0583	DNA-binding transcription factor activity
OIO47_10890	COG0318	PFAM AMP-dependent synthetase and ligase
OIO47_10895	COG1309	transcriptional regulator
OIO47_10900	COG1960	acyl-CoA dehydrogenase activity
OIO47_10905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO47_10910	COG1024	Enoyl-CoA hydratase
OIO47_10915	COG4770	biotin carboxylase activity
OIO47_10925	COG0583	DNA-binding transcription factor activity
OIO47_10945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO47_10965	COG3842	ATPase activity
OIO47_10970	COG1840	ABC-type Fe3 transport system, periplasmic component
OIO47_10985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO47_10990	COG1414	Transcriptional regulator
OIO47_11000	COG0583	DNA-binding transcription factor activity
OIO47_11005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO47_11010	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_11020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO47_11030	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_11035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO47_11040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO47_11045	COG2267	carboxylic ester hydrolase activity
OIO47_11065	COG3038	cytochrome b561
OIO47_11070	COG0753	catalase activity
OIO47_11075	COG2271	Major facilitator Superfamily
OIO47_11080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO47_11085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO47_11230	COG1116	anion transmembrane transporter activity
OIO47_11235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO47_11245	COG0864	Transcriptional regulator
OIO47_11255	COG1733	regulation of RNA biosynthetic process
OIO47_11260	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO47_11265	COG0439	Biotin carboxylase
OIO47_11280	COG1063	alcohol dehydrogenase
OIO47_11290	COG1309	transcriptional regulator
OIO47_11330	COG0038	chloride channel
OIO47_11335	COG4770	biotin carboxylase activity
OIO47_11355	COG1914	H( )-stimulated, divalent metal cation uptake system
OIO47_11415	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO47_11440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO47_11445	COG1116	anion transmembrane transporter activity
OIO47_11450	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO47_11480	COG0598	Magnesium transport protein CorA
OIO47_11490	COG1560	Kdo2-lipid A biosynthetic process
OIO47_11500	COG5006	permease, DMT superfamily
OIO47_11505	COG1522	sequence-specific DNA binding
OIO47_11520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OIO47_11530	COG4122	O-methyltransferase activity
OIO47_11565	COG1137	ATPase activity
OIO47_11570	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OIO47_11580	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OIO47_11585	COG0517	IMP dehydrogenase activity
OIO47_11585	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OIO47_11625	COG2814	Major facilitator Superfamily
OIO47_11660	COG1278	Cold shock
OIO47_11665	COG1280	lysine exporter protein (LysE YggA)
OIO47_11695	COG1570	exodeoxyribonuclease VII activity
OIO47_11745	COG0583	DNA-binding transcription factor activity
OIO47_11755	COG4638	Rieske (2fe-2S)
OIO47_11765	COG0543	2 iron, 2 sulfur cluster binding
OIO47_11765	COG0633	Ferredoxin
OIO47_11770	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_11775	COG3135	benzoate transporter
OIO47_11780	COG2814	Major facilitator Superfamily
OIO47_11795	COG1643	Atp-dependent helicase
OIO47_11800	COG0450	alkyl hydroperoxide reductase
OIO47_11810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIO47_11820	COG3634	alkyl hydroperoxide reductase activity
OIO47_11840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIO47_12000	COG0625	glutathione transferase activity
OIO47_12010	COG2885	chlorophyll binding
OIO47_12045	COG0542	response to heat
OIO47_12060	COG1765	OsmC-like protein
OIO47_12075	COG0667	Aldo Keto reductase
OIO47_12090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIO47_12105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIO47_12115	COG0527	aspartate kinase activity
OIO47_12125	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIO47_12135	COG3038	cytochrome b561
OIO47_12140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIO47_12145	COG2252	PERMEase
OIO47_12155	COG2072	flavoprotein involved in K transport
OIO47_12170	COG1741	Belongs to the pirin family
OIO47_12175	COG1309	transcriptional regulator
OIO47_12185	COG0300	oxidoreductase activity
OIO47_12190	COG2072	flavoprotein involved in K transport
OIO47_12195	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIO47_12240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO47_12260	COG2814	Major facilitator Superfamily
OIO47_12265	COG1024	Enoyl-CoA hydratase
OIO47_12270	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_12280	COG1960	acyl-CoA dehydrogenase activity
OIO47_12305	COG2186	Transcriptional regulator
OIO47_12310	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_12320	COG4948	Mandelate Racemase Muconate Lactonizing
OIO47_12325	COG2271	Major facilitator Superfamily
OIO47_12330	COG2721	sulfolactate sulfo-lyase activity
OIO47_12335	COG0697	spore germination
OIO47_12380	COG1113	amino acid transport
OIO47_12400	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_12420	COG0531	amino acid
OIO47_12430	COG1113	amino acid transport
OIO47_12470	COG3209	COG3209 Rhs family protein
OIO47_12490	COG4269	membrane
OIO47_12505	COG1902	pentaerythritol trinitrate reductase activity
OIO47_12505	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO47_12515	COG3706	GGDEF domain
OIO47_12515	COG2203	Gaf domain
OIO47_12515	COG4251	negative regulation of phosphorylation
OIO47_12515	COG5001	Diguanylate cyclase
OIO47_12525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO47_12550	COG4172	Belongs to the ABC transporter superfamily
OIO47_12555	COG4239	(ABC) transporter, permease
OIO47_12560	COG4174	ABC transporter (Permease)
OIO47_12570	COG1388	LysM domain
OIO47_12570	COG0741	lytic transglycosylase activity
OIO47_12570	COG1388	LysM domain
OIO47_12570	COG0741	lytic transglycosylase activity
OIO47_12575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO47_12615	COG0583	DNA-binding transcription factor activity
OIO47_12620	COG1279	arginine transmembrane transporter activity
OIO47_12640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO47_12645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO47_12650	COG0006	proline dipeptidase activity
OIO47_12685	COG2194	sulfuric ester hydrolase activity
OIO47_12850	COG5410	chromosome segregation
OIO47_13030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIO47_13050	COG3384	dioxygenase
OIO47_13060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO47_13065	COG2878	Part of a membrane complex involved in electron transport
OIO47_13070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIO47_13095	COG0768	penicillin binding
OIO47_13100	COG0742	ribosomal rna small subunit methyltransferase
OIO47_13115	COG0830	nickel cation binding
OIO47_13125	COG0804	urea catabolic process
OIO47_13165	COG1253	flavin adenine dinucleotide binding
OIO47_13170	COG2851	Citrate transporter
OIO47_13220	COG1773	rubredoxin
OIO47_13225	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO47_13235	COG0583	DNA-binding transcription factor activity
OIO47_13265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OIO47_13270	COG4181	ATPase activity
OIO47_13315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIO47_13340	COG0306	phosphate transporter
OIO47_13350	COG3958	Transketolase
OIO47_13355	COG3959	Transketolase, thiamine diphosphate binding domain
OIO47_13360	COG2271	Major facilitator Superfamily
OIO47_13365	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_13370	COG0583	DNA-binding transcription factor activity
OIO47_13390	COG2207	Transcriptional regulator
OIO47_13395	COG2066	Belongs to the glutaminase family
OIO47_13400	COG0242	peptide deformylase activity
OIO47_13405	COG0477	Major facilitator Superfamily
OIO47_13415	COG0028	Belongs to the TPP enzyme family
OIO47_13430	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_13435	COG2267	carboxylic ester hydrolase activity
OIO47_13445	COG2271	Major facilitator Superfamily
OIO47_13450	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO47_13460	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_13480	COG1414	Transcriptional regulator
OIO47_13495	COG1024	Enoyl-CoA hydratase
OIO47_13505	COG1215	transferase activity, transferring glycosyl groups
OIO47_13510	COG1649	PFAM Uncharacterised BCR, COG1649
OIO47_13510	COG0726	polysaccharide deacetylase
OIO47_13520	COG4681	YaeQ
OIO47_13530	COG0523	cobalamin synthesis protein
OIO47_13540	COG1607	acyl-coa hydrolase
OIO47_13550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO47_13555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO47_13560	COG1309	transcriptional regulator
OIO47_13585	COG2040	homocysteine
OIO47_13590	COG0531	amino acid
OIO47_13645	COG1595	DNA-templated transcription, initiation
OIO47_13655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO47_13660	COG0477	Major facilitator Superfamily
OIO47_13670	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OIO47_13730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO47_13815	COG0592	DNA-directed DNA polymerase activity
OIO47_13855	COG2026	Addiction module toxin, RelE StbE family
OIO47_14075	COG1484	DNA-dependent DNA replication
OIO47_14160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO47_14240	COG0405	Gamma-glutamyltransferase
OIO47_14245	COG2814	Major facilitator Superfamily
OIO47_14255	COG2050	protein possibly involved in aromatic compounds catabolism
OIO47_14270	COG1090	epimerase
OIO47_14290	COG0420	3'-5' exonuclease activity
OIO47_14315	COG0735	belongs to the Fur family
OIO47_14320	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO47_14340	COG0121	glutamine amidotransferase
OIO47_14355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO47_14365	COG0210	DNA helicase
OIO47_14370	COG2885	chlorophyll binding
OIO47_14375	COG0204	Acyl-transferase
OIO47_14390	COG2894	cell division
OIO47_14405	COG1280	lysine exporter protein (LysE YggA)
OIO47_14410	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OIO47_14410	COG1674	ftsk spoiiie
OIO47_14415	COG0492	ferredoxin-NADP+ reductase activity
OIO47_14420	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OIO47_14430	COG0456	acetyltransferase
OIO47_14475	COG1981	membrane
OIO47_14490	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIO47_14490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO47_14510	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_14520	COG0657	acetylesterase activity
OIO47_14530	COG0473	3-isopropylmalate dehydrogenase activity
OIO47_14535	COG0583	DNA-binding transcription factor activity
OIO47_14565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO47_14590	COG0564	pseudouridine synthase activity
OIO47_14600	COG0358	DNA primase activity
OIO47_14615	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OIO47_14645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO47_14675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIO47_14685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO47_14685	COG0351	phosphomethylpyrimidine kinase
OIO47_14685	COG0352	thiamine-phosphate diphosphorylase activity
OIO47_14690	COG1652	LysM domain
OIO47_14715	COG1399	metal-binding, possibly nucleic acid-binding protein
OIO47_14720	COG3101	peptidyl-lysine hydroxylation
OIO47_14725	COG0009	L-threonylcarbamoyladenylate synthase
OIO47_14730	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIO47_14735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIO47_14750	COG4106	trans-aconitate 2-methyltransferase activity
OIO47_14765	COG0596	Alpha beta hydrolase
OIO47_14765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO47_14765	COG2226	methyltransferase
OIO47_14770	COG1877	trehalose-phosphatase activity
OIO47_14775	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OIO47_14780	COG2223	nitrite transmembrane transporter activity
OIO47_14800	COG1196	nuclear chromosome segregation
OIO47_14810	COG0730	response to heat
OIO47_14825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIO47_14835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO47_14885	COG0489	protein tyrosine kinase activity
OIO47_14895	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO47_14895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO47_14925	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO47_14930	COG2081	HI0933 family
OIO47_14940	COG0668	transmembrane transport
OIO47_14960	COG0583	DNA-binding transcription factor activity
OIO47_14985	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIO47_14990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO47_15020	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIO47_15060	COG0745	RESPONSE REGULATOR receiver
OIO47_15080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO47_15085	COG0697	spore germination
OIO47_15120	COG0477	Major facilitator Superfamily
OIO47_15130	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_15150	COG0384	phenazine biosynthesis protein PhzF
OIO47_15195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO47_15210	COG0583	DNA-binding transcription factor activity
OIO47_15220	COG0583	DNA-binding transcription factor activity
OIO47_15235	COG0583	DNA-binding transcription factor activity
OIO47_15240	COG1053	succinate dehydrogenase
OIO47_15250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO47_15255	COG2814	Major facilitator Superfamily
OIO47_15260	COG1960	acyl-CoA dehydrogenase activity
OIO47_15265	COG0583	DNA-binding transcription factor activity
OIO47_15270	COG1063	alcohol dehydrogenase
OIO47_15300	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIO47_15305	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIO47_15310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO47_15330	COG2132	Multicopper oxidase
OIO47_15340	COG0561	phosphatase activity
OIO47_15345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIO47_15355	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO47_15370	COG1214	PFAM Peptidase M22, glycoprotease
OIO47_15440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIO47_15445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIO47_15450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIO47_15510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO47_15520	COG1846	Transcriptional regulator
OIO47_15525	COG1764	response to oxidative stress
OIO47_15565	COG0037	tRNA processing
OIO47_15575	COG0248	Ppx GppA phosphatase
OIO47_15605	COG0072	phenylalanine-tRNA ligase activity
OIO47_15650	COG1238	metal cluster binding
OIO47_15655	COG0625	glutathione transferase activity
OIO47_15670	COG0318	PFAM AMP-dependent synthetase and ligase
OIO47_15675	COG3028	Belongs to the UPF0307 family
OIO47_15680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO47_15700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OIO47_15705	COG0617	tRNA 3'-terminal CCA addition
OIO47_15710	COG1555	photosystem II stabilization
OIO47_15715	COG3956	TIGRFAM MazG family protein
OIO47_15725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO47_15745	COG2205	protein histidine kinase activity
OIO47_15745	COG0784	Response regulator, receiver
OIO47_15745	COG5002	protein histidine kinase activity
OIO47_15750	COG1024	Enoyl-CoA hydratase
OIO47_15755	COG2084	Dehydrogenase
OIO47_15760	COG3622	Belongs to the hyi family
OIO47_15795	COG0697	spore germination
OIO47_15805	COG2814	Major facilitator Superfamily
OIO47_15815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO47_15885	COG4774	siderophore transport
OIO47_15900	COG1271	oxidase subunit
OIO47_15905	COG1294	oxidase, subunit
OIO47_15975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO47_15985	COG0583	DNA-binding transcription factor activity
OIO47_15995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OIO47_16005	COG0084	hydrolase, TatD family'
OIO47_16020	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIO47_16050	COG0440	acetolactate synthase activity
OIO47_16055	COG0028	Belongs to the TPP enzyme family
OIO47_16080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO47_16085	COG0577	efflux transmembrane transporter activity
OIO47_16085	COG1136	(ABC) transporter
OIO47_16090	COG1538	Outer membrane efflux protein
OIO47_16105	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIO47_16110	COG1162	GTPase activity
OIO47_16120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OIO47_16160	COG1426	Protein conserved in bacteria
OIO47_16195	COG0793	Belongs to the peptidase S41A family
OIO47_16210	COG2267	carboxylic ester hydrolase activity
OIO47_16220	COG1012	belongs to the aldehyde dehydrogenase family
OIO47_16225	COG3265	gluconokinase activity
OIO47_16235	COG0800	Aldolase
OIO47_16245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIO47_16250	COG0857	belongs to the CobB CobQ family
OIO47_16250	COG0280	phosphate acetyltransferase
OIO47_16255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO47_16255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO47_16275	COG0740	serine-type endopeptidase activity
OIO47_16285	COG4774	siderophore transport
OIO47_16295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO47_16305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO47_16305	COG2813	Specifically methylates the guanine in position
OIO47_16405	COG0788	formyltetrahydrofolate deformylase activity
OIO47_16430	COG4651	solute:proton antiporter activity
OIO47_16430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO47_16450	COG0724	RNA recognition motif
OIO47_16455	COG0210	DNA helicase
OIO47_16480	COG1733	regulation of RNA biosynthetic process
OIO47_16490	COG2900	Belongs to the SlyX family
OIO47_16495	COG0488	(ABC) transporter
OIO47_16500	COG1280	lysine exporter protein (LysE YggA)
OIO47_16505	COG1560	Kdo2-lipid A biosynthetic process
OIO47_16515	COG1301	dicarboxylic acid transport
OIO47_16570	COG0473	3-isopropylmalate dehydrogenase activity
OIO47_16625	COG0583	DNA-binding transcription factor activity
OIO47_16635	COG0625	glutathione transferase activity
OIO47_16640	COG2378	regulation of single-species biofilm formation
OIO47_16645	COG0546	phosphoglycolate phosphatase activity
OIO47_16655	COG1530	ribonuclease E activity
OIO47_16660	COG0318	PFAM AMP-dependent synthetase and ligase
OIO47_16675	COG0583	DNA-binding transcription factor activity
OIO47_16680	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_16685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIO47_16695	COG0534	Mate efflux family protein
OIO47_16710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OIO47_16735	COG0493	'glutamate synthase
OIO47_16735	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO47_16745	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OIO47_16750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO47_16765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO47_16775	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OIO47_16775	COG0644	oxidoreductase
OIO47_16785	COG0425	Belongs to the sulfur carrier protein TusA family
OIO47_16790	COG4535	Mg2 and Co2 transporter CorC
OIO47_16800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO47_16820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIO47_16825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO47_16825	COG0475	glutathione-regulated potassium exporter activity
OIO47_16840	COG0484	heat shock protein binding
OIO47_16845	COG0789	Transcriptional regulator
OIO47_16850	COG0598	Magnesium transport protein CorA
OIO47_16865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO47_16870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO47_16875	COG1074	ATP-dependent DNA helicase activity
OIO47_16880	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OIO47_16900	COG2226	methyltransferase
OIO47_16920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIO47_16935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO47_16935	COG2111	Na H antiporter
OIO47_16940	COG1006	Multisubunit Na H antiporter MnhC subunit
OIO47_16945	COG0651	ATP synthesis coupled electron transport
OIO47_16950	COG1863	multisubunit Na H antiporter MnhE subunit
OIO47_16955	COG2212	antiporter activity
OIO47_16960	COG1320	monovalent cation:proton antiporter activity
OIO47_16975	COG0195	Participates in both transcription termination and antitermination
OIO47_17025	COG0237	dephospho-CoA kinase activity
OIO47_17035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO47_17050	COG0497	DNA recombination
OIO47_17060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIO47_17090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO47_17090	COG2169	Transcriptional regulator
OIO47_17095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIO47_17155	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIO47_17170	COG0326	Molecular chaperone. Has ATPase activity
OIO47_17185	COG2056	Na+-H+ antiporter family
OIO47_17285	COG0546	phosphoglycolate phosphatase activity
OIO47_17290	COG1716	ATPase activity
OIO47_17335	COG0181	hydroxymethylbilane synthase activity
OIO47_17345	COG3275	phosphorelay sensor kinase activity
OIO47_17365	COG1538	Outer membrane efflux protein
OIO47_17370	COG0697	spore germination
OIO47_17415	COG1061	Type III restriction enzyme res subunit
OIO47_17420	COG1002	Type II restriction enzyme, methylase subunits
OIO47_17430	COG0659	secondary active sulfate transmembrane transporter activity
OIO47_17435	COG0589	response to stress
OIO47_17480	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO47_17485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OIO47_17490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO47_17495	COG0772	Belongs to the SEDS family
OIO47_17520	COG4974	Belongs to the 'phage' integrase family
OIO47_17525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO47_17535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIO47_17545	COG2197	response regulator
OIO47_17560	COG0793	Belongs to the peptidase S41A family
OIO47_17565	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIO47_17570	COG0795	lipopolysaccharide-transporting ATPase activity
OIO47_17610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO47_17610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO47_17620	COG0004	ammonium transporteR
OIO47_17625	COG0347	Belongs to the P(II) protein family
OIO47_17660	COG1061	Type III restriction enzyme res subunit
OIO47_17665	COG1002	Type II restriction enzyme, methylase subunits
OIO47_17680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIO47_17695	COG0318	PFAM AMP-dependent synthetase and ligase
OIO47_17705	COG0477	Major facilitator Superfamily
OIO47_17710	COG2860	membrane
OIO47_17720	COG1253	flavin adenine dinucleotide binding
OIO47_17730	COG0477	Major facilitator Superfamily
OIO47_17735	COG3757	hydrolase, family 25
OIO47_17740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO47_17780	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIO47_17790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIO47_17860	COG0758	DNA mediated transformation
OIO47_17870	COG0697	spore germination
OIO47_17875	COG1309	transcriptional regulator
OIO47_17890	COG0386	Belongs to the glutathione peroxidase family
OIO47_17955	COG1121	(ABC) transporter
OIO47_17960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIO47_17965	COG1280	lysine exporter protein (LysE YggA)
OIO47_17970	COG2837	iron assimilation
OIO47_17980	COG0281	malic enzyme
OIO47_18025	COG0519	Catalyzes the synthesis of GMP from XMP
OIO47_18025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO47_18030	COG4399	Belongs to the UPF0754 family
OIO47_18035	COG2259	Doxx family
OIO47_18040	COG0586	Pfam SNARE associated Golgi protein
OIO47_18055	COG1192	Involved in chromosome partitioning
OIO47_18065	COG0271	Belongs to the BolA IbaG family
OIO47_18085	COG2267	carboxylic ester hydrolase activity
OIO47_18105	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OIO47_18105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIO47_18105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO47_18105	COG3321	synthase
OIO47_18110	COG1960	acyl-CoA dehydrogenase activity
OIO47_18120	COG2197	response regulator
OIO47_18130	COG3916	Acyl-homoserine-lactone synthase
OIO47_18135	COG0477	Major facilitator Superfamily
OIO47_18140	COG1024	Enoyl-CoA hydratase
OIO47_18145	COG1024	Enoyl-CoA hydratase
OIO47_18150	COG1960	acyl-CoA dehydrogenase activity
OIO47_18155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO47_18175	COG1113	amino acid transport
OIO47_18180	COG1113	amino acid transport
OIO47_18185	COG0251	oxidation-reduction process
OIO47_18225	COG0564	pseudouridine synthase activity
OIO47_18255	COG1051	belongs to the nudix hydrolase family
OIO47_18280	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIO47_18295	COG1802	Transcriptional regulator
OIO47_18305	COG1448	Aminotransferase
OIO47_18310	COG0277	FAD linked oxidase domain protein
OIO47_18320	COG2186	Transcriptional regulator
OIO47_18330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO47_18335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO47_18350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIO47_18360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OIO47_18370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OIO47_18375	COG0438	transferase activity, transferring glycosyl groups
OIO47_18385	COG0438	transferase activity, transferring glycosyl groups
OIO47_18405	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OIO47_18435	COG0728	peptidoglycan biosynthetic process
OIO47_18440	COG3023	N-Acetylmuramoyl-L-alanine amidase
OIO47_18475	COG1017	nitric oxide dioxygenase activity
OIO47_18475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO47_18500	COG0546	phosphoglycolate phosphatase activity
OIO47_18505	COG1028	Short-chain dehydrogenase reductase Sdr
OIO47_18525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO47_18530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO47_18535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO47_18540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO47_18545	COG1116	anion transmembrane transporter activity
OIO47_18550	COG1309	transcriptional regulator
OIO47_18555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO47_18565	COG0196	riboflavin kinase activity
OIO47_18570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIO47_18580	COG1047	Peptidyl-prolyl cis-trans
OIO47_18620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIO47_18625	COG0657	acetylesterase activity
OIO47_18645	COG0583	DNA-binding transcription factor activity
OIO47_18675	COG2951	lytic endotransglycosylase activity
OIO47_18680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIO47_18695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIO47_18705	COG0671	phosphoesterase, PA-phosphatase related
OIO47_18710	COG0861	Integral membrane protein TerC family
OIO47_18720	COG0754	glutathionylspermidine amidase activity
OIO47_18730	COG0402	S-adenosylhomocysteine deaminase activity
OIO47_18745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO47_18750	COG1230	cation diffusion facilitator family transporter
OIO47_18765	COG0706	membrane insertase activity
OIO47_18880	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO47_18885	COG4683	PFAM Phage derived protein Gp49-like (DUF891)