locus-tag	class	description
H2Q98_00125	COG3657	addiction module killer protein
H2Q98_00130	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H2Q98_00155	COG3173	Aminoglycoside phosphotransferase
H2Q98_00170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H2Q98_00180	COG1570	exodeoxyribonuclease VII activity
H2Q98_00200	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_00225	COG3621	Patatin-like phospholipase
H2Q98_00250	COG0582	viral genome integration into host DNA
H2Q98_00275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H2Q98_00310	COG2184	nucleotidyltransferase activity
H2Q98_00480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H2Q98_00515	COG1660	Displays ATPase and GTPase activities
H2Q98_00540	COG3077	Addiction module antitoxin, RelB DinJ family
H2Q98_00555	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H2Q98_00590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H2Q98_00600	COG1846	Transcriptional regulator
H2Q98_00605	COG1764	response to oxidative stress
H2Q98_00645	COG0037	tRNA processing
H2Q98_00655	COG0248	Ppx GppA phosphatase
H2Q98_00685	COG0072	phenylalanine-tRNA ligase activity
H2Q98_00715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H2Q98_00730	COG1238	metal cluster binding
H2Q98_00735	COG0625	glutathione transferase activity
H2Q98_00750	COG0318	PFAM AMP-dependent synthetase and ligase
H2Q98_00755	COG3028	Belongs to the UPF0307 family
H2Q98_00760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2Q98_00780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H2Q98_00785	COG0617	tRNA 3'-terminal CCA addition
H2Q98_00790	COG1555	photosystem II stabilization
H2Q98_00795	COG3956	TIGRFAM MazG family protein
H2Q98_00800	COG4221	oxidoreductase activity
H2Q98_00805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H2Q98_00820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H2Q98_00825	COG0784	Response regulator, receiver
H2Q98_00825	COG2205	protein histidine kinase activity
H2Q98_00825	COG5002	protein histidine kinase activity
H2Q98_00830	COG1024	Enoyl-CoA hydratase
H2Q98_00835	COG2084	Dehydrogenase
H2Q98_00840	COG3622	Belongs to the hyi family
H2Q98_00870	COG0697	spore germination
H2Q98_00880	COG2814	Major facilitator Superfamily
H2Q98_00915	COG0640	Transcriptional regulator
H2Q98_00950	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2Q98_00975	COG2132	Multicopper oxidase
H2Q98_00990	COG2205	protein histidine kinase activity
H2Q98_01075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H2Q98_01090	COG0583	DNA-binding transcription factor activity
H2Q98_01100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H2Q98_01110	COG0084	hydrolase, TatD family'
H2Q98_01125	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H2Q98_01145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H2Q98_01150	COG0440	acetolactate synthase activity
H2Q98_01155	COG0028	Belongs to the TPP enzyme family
H2Q98_01175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2Q98_01180	COG0577	efflux transmembrane transporter activity
H2Q98_01180	COG1136	(ABC) transporter
H2Q98_01210	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H2Q98_01215	COG1162	GTPase activity
H2Q98_01225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H2Q98_01245	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H2Q98_01265	COG1426	Protein conserved in bacteria
H2Q98_01300	COG0793	Belongs to the peptidase S41A family
H2Q98_01315	COG2267	carboxylic ester hydrolase activity
H2Q98_01325	COG1012	belongs to the aldehyde dehydrogenase family
H2Q98_01330	COG3265	gluconokinase activity
H2Q98_01340	COG0800	Aldolase
H2Q98_01355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H2Q98_01360	COG0280	phosphate acetyltransferase
H2Q98_01360	COG0857	belongs to the CobB CobQ family
H2Q98_01365	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H2Q98_01365	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H2Q98_01385	COG0740	serine-type endopeptidase activity
H2Q98_01395	COG4774	siderophore transport
H2Q98_01405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H2Q98_01415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2Q98_01415	COG2813	Specifically methylates the guanine in position
H2Q98_01515	COG0788	formyltetrahydrofolate deformylase activity
H2Q98_01540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2Q98_01540	COG4651	solute:proton antiporter activity
H2Q98_01560	COG0724	RNA recognition motif
H2Q98_01565	COG0210	DNA helicase
H2Q98_01590	COG1733	regulation of RNA biosynthetic process
H2Q98_01600	COG2900	Belongs to the SlyX family
H2Q98_01615	COG1560	Kdo2-lipid A biosynthetic process
H2Q98_01625	COG1301	dicarboxylic acid transport
H2Q98_01680	COG0473	3-isopropylmalate dehydrogenase activity
H2Q98_01705	COG0583	DNA-binding transcription factor activity
H2Q98_01745	COG0583	DNA-binding transcription factor activity
H2Q98_01755	COG0625	glutathione transferase activity
H2Q98_01760	COG2378	regulation of single-species biofilm formation
H2Q98_01765	COG0546	phosphoglycolate phosphatase activity
H2Q98_01775	COG1530	ribonuclease E activity
H2Q98_01780	COG0318	PFAM AMP-dependent synthetase and ligase
H2Q98_01795	COG0583	DNA-binding transcription factor activity
H2Q98_01800	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_01805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H2Q98_01815	COG0534	Mate efflux family protein
H2Q98_01830	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H2Q98_01855	COG0493	'glutamate synthase
H2Q98_01865	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H2Q98_01870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2Q98_01885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H2Q98_01895	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H2Q98_01895	COG0644	oxidoreductase
H2Q98_01910	COG4535	Mg2 and Co2 transporter CorC
H2Q98_01920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2Q98_01940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H2Q98_01950	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H2Q98_01960	COG0484	heat shock protein binding
H2Q98_01965	COG0789	Transcriptional regulator
H2Q98_01970	COG0598	Magnesium transport protein CorA
H2Q98_01975	COG1185	polyribonucleotide nucleotidyltransferase activity
H2Q98_01990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H2Q98_01995	COG1074	ATP-dependent DNA helicase activity
H2Q98_02000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H2Q98_02020	COG2226	methyltransferase
H2Q98_02035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2Q98_02045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H2Q98_02060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H2Q98_02060	COG2111	Na H antiporter
H2Q98_02065	COG1006	Multisubunit Na H antiporter MnhC subunit
H2Q98_02070	COG0651	ATP synthesis coupled electron transport
H2Q98_02080	COG2212	antiporter activity
H2Q98_02090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H2Q98_02100	COG0195	Participates in both transcription termination and antitermination
H2Q98_02150	COG0237	dephospho-CoA kinase activity
H2Q98_02160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H2Q98_02175	COG0497	DNA recombination
H2Q98_02185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H2Q98_02220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H2Q98_02220	COG2169	Transcriptional regulator
H2Q98_02225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H2Q98_02290	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H2Q98_02305	COG0326	Molecular chaperone. Has ATPase activity
H2Q98_02320	COG2056	Na+-H+ antiporter family
H2Q98_02390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H2Q98_02420	COG0546	phosphoglycolate phosphatase activity
H2Q98_02425	COG1716	ATPase activity
H2Q98_02470	COG0181	hydroxymethylbilane synthase activity
H2Q98_02480	COG3275	phosphorelay sensor kinase activity
H2Q98_02500	COG1538	Outer membrane efflux protein
H2Q98_02510	COG0697	spore germination
H2Q98_02530	COG0494	nUDIX hydrolase
H2Q98_02535	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H2Q98_02540	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H2Q98_02545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H2Q98_02550	COG0772	Belongs to the SEDS family
H2Q98_02575	COG4974	Belongs to the 'phage' integrase family
H2Q98_02580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2Q98_02590	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H2Q98_02600	COG2197	response regulator
H2Q98_02615	COG0793	Belongs to the peptidase S41A family
H2Q98_02620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H2Q98_02625	COG0795	lipopolysaccharide-transporting ATPase activity
H2Q98_02665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H2Q98_02665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H2Q98_02675	COG0004	ammonium transporteR
H2Q98_02680	COG0347	Belongs to the P(II) protein family
H2Q98_02690	COG0606	chelatase, subunit chli
H2Q98_02695	COG0431	NADPH-dependent FMN reductase
H2Q98_02700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2Q98_02705	COG0235	Class ii aldolase
H2Q98_02710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2Q98_02730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H2Q98_02745	COG0318	PFAM AMP-dependent synthetase and ligase
H2Q98_02755	COG0477	Major facilitator Superfamily
H2Q98_02760	COG2860	membrane
H2Q98_02770	COG1253	flavin adenine dinucleotide binding
H2Q98_02780	COG2814	Major facilitator Superfamily
H2Q98_02790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H2Q98_02830	COG0655	NAD(P)H dehydrogenase (quinone) activity
H2Q98_02845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H2Q98_02875	COG1309	transcriptional regulator
H2Q98_02910	COG0758	DNA mediated transformation
H2Q98_02920	COG0697	spore germination
H2Q98_02925	COG1309	transcriptional regulator
H2Q98_02940	COG0386	Belongs to the glutathione peroxidase family
H2Q98_02955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H2Q98_02965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H2Q98_03005	COG1121	(ABC) transporter
H2Q98_03010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H2Q98_03015	COG1280	lysine exporter protein (LysE YggA)
H2Q98_03020	COG2837	iron assimilation
H2Q98_03025	COG0281	malic enzyme
H2Q98_03065	COG0519	Catalyzes the synthesis of GMP from XMP
H2Q98_03065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H2Q98_03070	COG4399	Belongs to the UPF0754 family
H2Q98_03075	COG2259	Doxx family
H2Q98_03080	COG0586	Pfam SNARE associated Golgi protein
H2Q98_03095	COG1192	Involved in chromosome partitioning
H2Q98_03105	COG0271	Belongs to the BolA IbaG family
H2Q98_03145	COG3321	synthase
H2Q98_03145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2Q98_03145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H2Q98_03145	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H2Q98_03150	COG1960	acyl-CoA dehydrogenase activity
H2Q98_03155	COG0318	PFAM AMP-dependent synthetase and ligase
H2Q98_03160	COG2197	response regulator
H2Q98_03165	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_03175	COG3916	Acyl-homoserine-lactone synthase
H2Q98_03180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2Q98_03190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H2Q98_03195	COG1113	amino acid transport
H2Q98_03200	COG0697	spore germination
H2Q98_03205	COG0477	Major facilitator Superfamily
H2Q98_03210	COG1024	Enoyl-CoA hydratase
H2Q98_03215	COG1024	Enoyl-CoA hydratase
H2Q98_03220	COG1960	acyl-CoA dehydrogenase activity
H2Q98_03225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2Q98_03245	COG1113	amino acid transport
H2Q98_03250	COG1113	amino acid transport
H2Q98_03255	COG0251	oxidation-reduction process
H2Q98_03295	COG0564	pseudouridine synthase activity
H2Q98_03315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H2Q98_03330	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_03340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H2Q98_03355	COG1802	Transcriptional regulator
H2Q98_03365	COG1448	Aminotransferase
H2Q98_03370	COG0277	FAD linked oxidase domain protein
H2Q98_03380	COG2186	Transcriptional regulator
H2Q98_03390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H2Q98_03405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H2Q98_03410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H2Q98_03450	COG1091	dTDP-4-dehydrorhamnose reductase activity
H2Q98_03465	COG2244	polysaccharide biosynthetic process
H2Q98_03480	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H2Q98_03510	COG0728	peptidoglycan biosynthetic process
H2Q98_03515	COG3023	N-Acetylmuramoyl-L-alanine amidase
H2Q98_03570	COG0546	phosphoglycolate phosphatase activity
H2Q98_03575	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_03590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H2Q98_03590	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H2Q98_03595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2Q98_03600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2Q98_03605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2Q98_03610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2Q98_03615	COG1116	anion transmembrane transporter activity
H2Q98_03620	COG1309	transcriptional regulator
H2Q98_03625	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H2Q98_03635	COG0196	riboflavin kinase activity
H2Q98_03640	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H2Q98_03650	COG1047	Peptidyl-prolyl cis-trans
H2Q98_03690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H2Q98_03745	COG2951	lytic endotransglycosylase activity
H2Q98_03750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H2Q98_03765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H2Q98_03775	COG0671	phosphoesterase, PA-phosphatase related
H2Q98_03780	COG0861	Integral membrane protein TerC family
H2Q98_03790	COG0754	glutathionylspermidine amidase activity
H2Q98_03800	COG0402	S-adenosylhomocysteine deaminase activity
H2Q98_03815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2Q98_03820	COG1230	cation diffusion facilitator family transporter
H2Q98_03835	COG0706	membrane insertase activity
H2Q98_03860	COG0592	DNA-directed DNA polymerase activity
H2Q98_03870	COG0187	DNA topoisomerase II activity
H2Q98_03885	COG0488	(ABC) transporter
H2Q98_03910	COG0596	Alpha beta hydrolase
H2Q98_03915	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H2Q98_03920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H2Q98_03950	COG0625	glutathione transferase activity
H2Q98_03960	COG0733	neurotransmitter:sodium symporter activity
H2Q98_04000	COG2233	PERMEase
H2Q98_04015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2Q98_04050	COG2814	Major facilitator Superfamily
H2Q98_04055	COG0656	L-ascorbic acid biosynthetic process
H2Q98_04060	COG0583	DNA-binding transcription factor activity
H2Q98_04075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2Q98_04080	COG1064	alcohol dehydrogenase
H2Q98_04085	COG2818	Glycosylase
H2Q98_04100	COG1194	a g-specific adenine glycosylase
H2Q98_04115	COG5487	UPF0391 membrane protein
H2Q98_04120	COG2983	Belongs to the UPF0260 family
H2Q98_04125	COG2133	pyrroloquinoline quinone binding
H2Q98_04130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H2Q98_04135	COG2116	formate transmembrane transporter activity
H2Q98_04155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2Q98_04160	COG1335	isochorismatase
H2Q98_04165	COG0385	Bile acid
H2Q98_04170	COG0534	Mate efflux family protein
H2Q98_04175	COG1683	Conserved Protein
H2Q98_04190	COG0346	lactoylglutathione lyase activity
H2Q98_04195	COG0625	glutathione transferase activity
H2Q98_04205	COG1113	amino acid transport
H2Q98_04215	COG0523	cobalamin synthesis protein
H2Q98_04225	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_04235	COG2188	Transcriptional regulator
H2Q98_04265	COG0010	Belongs to the arginase family
H2Q98_04295	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_04305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H2Q98_04360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H2Q98_04370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H2Q98_04375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H2Q98_04450	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_04480	COG0534	Mate efflux family protein
H2Q98_04485	COG0436	Aminotransferase
H2Q98_04490	COG2733	membrane
H2Q98_04505	COG2918	glutathione biosynthetic process
H2Q98_04525	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_04535	COG3150	esterase
H2Q98_04545	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H2Q98_04555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2Q98_04565	COG2233	PERMEase
H2Q98_04570	COG2351	hydroxyisourate hydrolase activity
H2Q98_04605	COG3706	GGDEF domain
H2Q98_04620	COG1393	Belongs to the ArsC family
H2Q98_04625	COG0708	Exodeoxyribonuclease III
H2Q98_04655	COG0189	ligase activity
H2Q98_04675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H2Q98_04685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H2Q98_04700	COG4942	peptidase
H2Q98_04710	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2Q98_04720	COG2119	membrane
H2Q98_04725	COG4774	siderophore transport
H2Q98_04730	COG0426	domain, Protein
H2Q98_04730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2Q98_04750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H2Q98_04770	COG1902	pentaerythritol trinitrate reductase activity
H2Q98_04775	COG1519	Transferase
H2Q98_04780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H2Q98_04785	COG0668	transmembrane transport
H2Q98_04795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2Q98_04800	COG1335	isochorismatase
H2Q98_04805	COG1522	sequence-specific DNA binding
H2Q98_04830	COG2205	protein histidine kinase activity
H2Q98_04830	COG0784	Response regulator, receiver
H2Q98_04830	COG2198	Histidine kinase
H2Q98_04835	COG3162	membrane
H2Q98_04840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2Q98_04850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2Q98_04860	COG3706	GGDEF domain
H2Q98_04875	COG1309	transcriptional regulator
H2Q98_04895	COG0300	oxidoreductase activity
H2Q98_04900	COG0789	Transcriptional regulator
H2Q98_04905	COG0351	phosphomethylpyrimidine kinase
H2Q98_04905	COG0352	thiamine-phosphate diphosphorylase activity
H2Q98_04905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H2Q98_04915	COG2814	Major facilitator Superfamily
H2Q98_04930	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H2Q98_04940	COG1113	amino acid transport
H2Q98_04950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2Q98_04955	COG1012	belongs to the aldehyde dehydrogenase family
H2Q98_04965	COG1335	isochorismatase
H2Q98_04995	COG2814	Major facilitator Superfamily
H2Q98_05000	COG0583	DNA-binding transcription factor activity
H2Q98_05020	COG0667	Aldo Keto reductase
H2Q98_05045	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_05075	COG1733	regulation of RNA biosynthetic process
H2Q98_05085	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2Q98_05095	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H2Q98_05100	COG2207	Transcriptional regulator
H2Q98_05160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H2Q98_05175	COG0697	spore germination
H2Q98_05200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H2Q98_05230	COG0427	acetyl-CoA hydrolase
H2Q98_05240	COG2205	protein histidine kinase activity
H2Q98_05245	COG0745	RESPONSE REGULATOR receiver
H2Q98_05255	COG0659	secondary active sulfate transmembrane transporter activity
H2Q98_05260	COG4221	oxidoreductase activity
H2Q98_05265	COG2873	o-acetylhomoserine
H2Q98_05270	COG0488	(ABC) transporter
H2Q98_05350	COG0833	amino acid
H2Q98_05395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H2Q98_05400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H2Q98_05415	COG2226	methyltransferase
H2Q98_05465	COG0067	glutamate synthase
H2Q98_05465	COG0069	glutamate synthase activity
H2Q98_05465	COG0070	glutamate synthase
H2Q98_05470	COG0493	'glutamate synthase
H2Q98_05480	COG1704	LemA family
H2Q98_05485	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H2Q98_05495	COG4969	Belongs to the N-Me-Phe pilin family
H2Q98_05505	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_05515	COG3328	transposase activity
H2Q98_05525	COG3307	-O-antigen
H2Q98_05550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H2Q98_05565	COG0194	GDP metabolic process
H2Q98_05615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H2Q98_05625	COG0335	large ribosomal subunit rRNA binding
H2Q98_05635	COG5380	lipid catabolic process
H2Q98_05640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H2Q98_05655	COG5006	permease, DMT superfamily
H2Q98_05660	COG5006	permease, DMT superfamily
H2Q98_05665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H2Q98_05670	COG0277	FAD linked oxidase domain protein
H2Q98_05680	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H2Q98_05685	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2Q98_05700	COG1289	transmembrane transporter activity
H2Q98_05710	COG0628	permease
H2Q98_05715	COG1192	Involved in chromosome partitioning
H2Q98_05745	COG0833	amino acid
H2Q98_05750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H2Q98_05755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H2Q98_05765	COG1012	belongs to the aldehyde dehydrogenase family
H2Q98_05800	COG3328	transposase activity
H2Q98_05810	COG0583	DNA-binding transcription factor activity
H2Q98_05825	COG5002	protein histidine kinase activity
H2Q98_05850	COG0752	glycyl-tRNA synthetase alpha subunit
H2Q98_05875	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H2Q98_05875	COG0517	IMP dehydrogenase activity
H2Q98_05875	COG0617	tRNA 3'-terminal CCA addition
H2Q98_05880	COG1983	PspC domain protein
H2Q98_05890	COG1960	acyl-CoA dehydrogenase activity
H2Q98_05905	COG0408	coproporphyrinogen oxidase activity
H2Q98_05925	COG0513	Belongs to the DEAD box helicase family
H2Q98_05935	COG1127	ABC transporter
H2Q98_05940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H2Q98_05950	COG2854	intermembrane phospholipid transfer
H2Q98_05960	COG0598	Magnesium transport protein CorA
H2Q98_05970	COG0494	nUDIX hydrolase
H2Q98_05975	COG1040	competence protein
H2Q98_05980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H2Q98_05995	COG2937	Belongs to the GPAT DAPAT family
H2Q98_06000	COG1946	Acyl-CoA thioesterase
H2Q98_06005	COG1301	dicarboxylic acid transport
H2Q98_06020	COG1959	2 iron, 2 sulfur cluster binding
H2Q98_06025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2Q98_06025	COG1017	nitric oxide dioxygenase activity
H2Q98_06035	COG0433	COG0433 Predicted ATPase
H2Q98_06040	COG0626	cystathionine gamma-synthase activity
H2Q98_06055	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H2Q98_06060	COG0088	Forms part of the polypeptide exit tunnel
H2Q98_06195	COG1960	acyl-CoA dehydrogenase activity
H2Q98_06200	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H2Q98_06230	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H2Q98_06235	COG0339	signal peptide processing
H2Q98_06240	COG0557	exoribonuclease II activity
H2Q98_06290	COG0179	Fumarylacetoacetate (FAA) hydrolase
H2Q98_06295	COG1295	ribonuclease BN
H2Q98_06330	COG1702	phosphate starvation-inducible protein PhoH
H2Q98_06340	COG0741	lytic transglycosylase activity
H2Q98_06340	COG1196	nuclear chromosome segregation
H2Q98_06340	COG0739	heme binding
H2Q98_06360	COG3328	transposase activity
H2Q98_06375	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H2Q98_06380	COG1183	phosphatidylcholine synthase activity
H2Q98_06425	COG1960	acyl-CoA dehydrogenase activity
H2Q98_06430	COG1309	transcriptional regulator
H2Q98_06445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H2Q98_06450	COG1960	acyl-CoA dehydrogenase activity
H2Q98_06480	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_06490	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_06500	COG2969	positive regulation of protein catabolic process
H2Q98_06505	COG0625	glutathione transferase activity
H2Q98_06510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H2Q98_06515	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H2Q98_06520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H2Q98_06525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H2Q98_06530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H2Q98_06550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H2Q98_06560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2Q98_06565	COG1408	metallophosphoesterase
H2Q98_06570	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H2Q98_06570	COG2885	chlorophyll binding
H2Q98_06575	COG2199	diguanylate cyclase activity
H2Q98_06645	COG1607	acyl-coa hydrolase
H2Q98_06680	COG2350	Protein conserved in bacteria
H2Q98_06695	COG3781	membrane
H2Q98_06705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H2Q98_06710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H2Q98_06720	COG1862	Preprotein translocase
H2Q98_06755	COG2198	Histidine kinase
H2Q98_06755	COG0784	Response regulator, receiver
H2Q98_06755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2Q98_06755	COG2205	protein histidine kinase activity
H2Q98_06760	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H2Q98_06775	COG0726	polysaccharide deacetylase
H2Q98_06790	COG1216	Glycosyl transferase, family 2
H2Q98_06840	COG0625	glutathione transferase activity
H2Q98_06845	COG0583	DNA-binding transcription factor activity
H2Q98_06850	COG1960	acyl-CoA dehydrogenase activity
H2Q98_06855	COG1960	acyl-CoA dehydrogenase activity
H2Q98_06865	COG2205	protein histidine kinase activity
H2Q98_06870	COG0745	RESPONSE REGULATOR receiver
H2Q98_06880	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H2Q98_06900	COG2096	Adenosyltransferase
H2Q98_06905	COG4206	TonB-dependent receptor
H2Q98_06950	COG0285	dihydrofolate synthase activity
H2Q98_06970	COG0450	alkyl hydroperoxide reductase
H2Q98_06985	COG0477	Major facilitator Superfamily
H2Q98_06990	COG1272	protein, Hemolysin III
H2Q98_07000	COG2153	protein acetylation
H2Q98_07020	COG0183	Belongs to the thiolase family
H2Q98_07025	COG2207	Transcriptional regulator
H2Q98_07045	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2Q98_07065	COG0183	Belongs to the thiolase family
H2Q98_07075	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H2Q98_07075	COG2885	chlorophyll binding
H2Q98_07085	COG1690	Belongs to the RtcB family
H2Q98_07090	COG0833	amino acid
H2Q98_07100	COG2233	PERMEase
H2Q98_07130	COG2094	Belongs to the DNA glycosylase MPG family
H2Q98_07135	COG4772	TonB-dependent receptor
H2Q98_07140	COG1902	pentaerythritol trinitrate reductase activity
H2Q98_07155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2Q98_07160	COG0354	folic acid binding
H2Q98_07180	COG2233	PERMEase
H2Q98_07185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2Q98_07190	COG0251	oxidation-reduction process
H2Q98_07195	COG1335	isochorismatase
H2Q98_07200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2Q98_07205	COG0778	Nitroreductase
H2Q98_07210	COG0596	Alpha beta hydrolase
H2Q98_07215	COG3189	MarR family transcriptional regulator
H2Q98_07220	COG2824	Alkylphosphonate utilization operon protein PhnA
H2Q98_07225	COG3422	double-strand break repair
H2Q98_07250	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_07275	COG0840	transmembrane signaling receptor activity
H2Q98_07295	COG5510	response to toxic substance
H2Q98_07305	COG2832	Protein of unknown function (DUF454)
H2Q98_07310	COG1376	ErfK ybiS ycfS ynhG family protein
H2Q98_07350	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H2Q98_07360	COG1289	transmembrane transporter activity
H2Q98_07365	COG2814	Major facilitator Superfamily
H2Q98_07385	COG1115	amino acid carrier protein
H2Q98_07390	COG1752	Esterase of the alpha-beta hydrolase superfamily
H2Q98_07395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H2Q98_07400	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H2Q98_07405	COG3590	peptidase
H2Q98_07430	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H2Q98_07440	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H2Q98_07445	COG1077	Cell shape determining protein MreB Mrl
H2Q98_07450	COG1792	Involved in formation and maintenance of cell shape
H2Q98_07455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H2Q98_07460	COG0424	maF-like protein
H2Q98_07465	COG1530	ribonuclease E activity
H2Q98_07475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2Q98_07495	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2Q98_07520	COG2207	Transcriptional regulator
H2Q98_07550	COG3046	protein related to deoxyribodipyrimidine photolyase
H2Q98_07560	COG1113	amino acid transport
H2Q98_07565	COG2828	Protein conserved in bacteria
H2Q98_07570	COG0142	geranyltranstransferase activity
H2Q98_07575	COG2315	Protein conserved in bacteria
H2Q98_07590	COG1752	Esterase of the alpha-beta hydrolase superfamily
H2Q98_07615	COG2194	sulfuric ester hydrolase activity
H2Q98_07620	COG0745	RESPONSE REGULATOR receiver
H2Q98_07625	COG0642	Histidine kinase
H2Q98_07640	COG0004	ammonium transporteR
H2Q98_07645	COG0583	DNA-binding transcription factor activity
H2Q98_07670	COG0525	valine-tRNA ligase activity
H2Q98_07680	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_07690	COG0393	Putative heavy-metal-binding
H2Q98_07695	COG0393	Putative heavy-metal-binding
H2Q98_07700	COG1538	Outer membrane efflux protein
H2Q98_07710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2Q98_07715	COG0671	phosphoesterase, PA-phosphatase related
H2Q98_07740	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H2Q98_07755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H2Q98_07755	COG1648	precorrin-2 dehydrogenase activity
H2Q98_07760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H2Q98_07795	COG0531	amino acid
H2Q98_07810	COG0321	lipoyl(octanoyl) transferase activity
H2Q98_07815	COG2921	Belongs to the UPF0250 family
H2Q98_07855	COG2009	succinate dehydrogenase
H2Q98_07860	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H2Q98_07865	COG1053	succinate dehydrogenase
H2Q98_07870	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H2Q98_07895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2Q98_07915	COG2354	Protein conserved in bacteria
H2Q98_07920	COG2321	neutral zinc metallopeptidase
H2Q98_07940	COG2843	Capsule synthesis protein
H2Q98_07960	COG0589	response to stress
H2Q98_07970	COG0251	oxidation-reduction process
H2Q98_07975	COG1309	transcriptional regulator
H2Q98_07990	COG0505	Belongs to the CarA family
H2Q98_08020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H2Q98_08025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H2Q98_08065	COG2264	protein methyltransferase activity
H2Q98_08075	COG0477	Major facilitator Superfamily
H2Q98_08080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H2Q98_08095	COG1597	lipid kinase activity
H2Q98_08100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H2Q98_08110	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_08135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2Q98_08140	COG0584	glycerophosphoryl diester phosphodiesterase
H2Q98_08160	COG0741	lytic transglycosylase activity
H2Q98_08180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H2Q98_08205	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_08220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2Q98_08225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2Q98_08230	COG0778	Nitroreductase
H2Q98_08245	COG1929	Belongs to the glycerate kinase type-1 family
H2Q98_08250	COG0243	molybdopterin cofactor binding
H2Q98_08255	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H2Q98_08260	COG3339	Conserved Protein
H2Q98_08285	COG1115	amino acid carrier protein
H2Q98_08290	COG1113	amino acid transport
H2Q98_08300	COG0019	diaminopimelate decarboxylase activity
H2Q98_08310	COG1280	lysine exporter protein (LysE YggA)
H2Q98_08315	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H2Q98_08345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2Q98_08380	COG4591	ABC-type transport system involved in lipoprotein release permease component
H2Q98_08385	COG1136	(ABC) transporter
H2Q98_08395	COG3328	transposase activity
H2Q98_08410	COG0616	signal peptide processing
H2Q98_08410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H2Q98_08415	COG0596	Alpha beta hydrolase
H2Q98_08420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H2Q98_08430	COG0628	permease
H2Q98_08465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H2Q98_08485	COG0823	Involved in the tonB-independent uptake of proteins
H2Q98_08505	COG0824	Thioesterase
H2Q98_08510	COG1473	amidohydrolase
H2Q98_08530	COG0047	phosphoribosylformylglycinamidine synthase activity
H2Q98_08530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H2Q98_08535	COG2814	Major facilitator Superfamily
H2Q98_08540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H2Q98_08545	COG1024	Enoyl-CoA hydratase
H2Q98_08550	COG1051	belongs to the nudix hydrolase family
H2Q98_08550	COG1056	cytidyltransferase-related domain
H2Q98_08565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H2Q98_08580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H2Q98_08595	COG4625	pathogenesis
H2Q98_08600	COG0583	DNA-binding transcription factor activity
H2Q98_08605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H2Q98_08610	COG4208	sulfate ABC transporter
H2Q98_08615	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H2Q98_08625	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H2Q98_08630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H2Q98_08635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H2Q98_08655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2Q98_08665	COG0481	GTPase activity
H2Q98_08670	COG0681	Belongs to the peptidase S26 family
H2Q98_08680	COG0571	ribonuclease III activity
H2Q98_08685	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H2Q98_08700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H2Q98_08710	COG4221	oxidoreductase activity
H2Q98_08740	COG0436	Aminotransferase
H2Q98_08760	COG0556	nucleotide-excision repair
H2Q98_08770	COG2962	Rard protein
H2Q98_08815	COG2070	2-Nitropropane dioxygenase
H2Q98_08830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H2Q98_08845	COG1215	transferase activity, transferring glycosyl groups
H2Q98_08860	COG0415	Belongs to the DNA photolyase family
H2Q98_08870	COG1252	NADH dehydrogenase
H2Q98_08875	COG1686	Belongs to the peptidase S11 family
H2Q98_08890	COG1187	pseudouridine synthase activity
H2Q98_08905	COG0477	Major facilitator Superfamily
H2Q98_08910	COG0583	DNA-binding transcription factor activity
H2Q98_08925	COG0612	Peptidase, M16
H2Q98_08950	COG0352	thiamine-phosphate diphosphorylase activity
H2Q98_08985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2Q98_09000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2Q98_09005	COG0076	glutamate decarboxylase activity
H2Q98_09015	COG1522	sequence-specific DNA binding
H2Q98_09020	COG3961	Belongs to the TPP enzyme family
H2Q98_09025	COG1113	amino acid transport
H2Q98_09030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H2Q98_09035	COG0573	inorganic phosphate transmembrane transporter activity
H2Q98_09045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H2Q98_09050	COG0616	signal peptide processing
H2Q98_09060	COG3328	transposase activity
H2Q98_09095	COG3328	transposase activity
H2Q98_09100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H2Q98_09105	COG1686	Belongs to the peptidase S11 family
H2Q98_09130	COG0583	DNA-binding transcription factor activity
H2Q98_09135	COG1067	ATP-dependent peptidase activity
H2Q98_09175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H2Q98_09180	COG1966	Carbon starvation protein
H2Q98_09185	COG2879	small protein
H2Q98_09225	COG3328	transposase activity
H2Q98_09240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2Q98_09245	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2Q98_09250	COG4605	iron ion homeostasis
H2Q98_09255	COG4604	ABC transporter, ATP-binding protein
H2Q98_09260	COG4607	ABC-type enterochelin transport system periplasmic component
H2Q98_09265	COG4774	siderophore transport
H2Q98_09275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2Q98_09280	COG1021	2,3-dihydroxybenzoate-AMP ligase
H2Q98_09285	COG1535	isochorismatase
H2Q98_09285	COG3433	isochorismatase activity
H2Q98_09295	COG1132	(ABC) transporter
H2Q98_09305	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H2Q98_09315	COG1169	isochorismate synthase
H2Q98_09330	COG3739	integral membrane protein
H2Q98_09360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H2Q98_09370	COG2840	Smr protein MutS2
H2Q98_09405	COG0512	Glutamine amidotransferase of anthranilate synthase
H2Q98_09460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H2Q98_09465	COG4197	protein conserved in bacteria, prophage-related
H2Q98_09710	COG3772	lysozyme
H2Q98_09715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H2Q98_09730	COG0582	viral genome integration into host DNA
H2Q98_09740	COG3104	oligopeptide transport
H2Q98_09745	COG0174	glutamine synthetase
H2Q98_09755	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H2Q98_09790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H2Q98_09795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H2Q98_09800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2Q98_09820	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H2Q98_09825	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H2Q98_09830	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H2Q98_09845	COG1960	acyl-CoA dehydrogenase activity
H2Q98_09850	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H2Q98_09855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2Q98_09865	COG2223	nitrite transmembrane transporter activity
H2Q98_09875	COG0024	Methionine aminopeptidase
H2Q98_09880	COG0052	Belongs to the universal ribosomal protein uS2 family
H2Q98_09920	COG2951	lytic endotransglycosylase activity
H2Q98_09925	COG0772	Belongs to the SEDS family
H2Q98_09940	COG0842	Transport permease protein
H2Q98_09945	COG1131	(ABC) transporter
H2Q98_09990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2Q98_10000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2Q98_10005	COG4215	(ABC) transporter
H2Q98_10010	COG4160	amino acid transport
H2Q98_10015	COG4598	ABC transporter
H2Q98_10025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H2Q98_10035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2Q98_10040	COG0384	phenazine biosynthesis protein PhzF
H2Q98_10050	COG1720	tRNA m6t6A37 methyltransferase activity
H2Q98_10070	COG0745	RESPONSE REGULATOR receiver
H2Q98_10075	COG0642	Histidine kinase
H2Q98_10085	COG0494	nUDIX hydrolase
H2Q98_10095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H2Q98_10100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H2Q98_10105	COG3139	Protein of unknown function (DUF1315)
H2Q98_10110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H2Q98_10115	COG1301	dicarboxylic acid transport
H2Q98_10120	COG1960	acyl-CoA dehydrogenase activity
H2Q98_10135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H2Q98_10145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H2Q98_10150	COG2195	Cleaves the N-terminal amino acid of tripeptides
H2Q98_10170	COG1690	Belongs to the RtcB family
H2Q98_10175	COG1234	tRNA 3'-trailer cleavage
H2Q98_10180	COG4650	regulator
H2Q98_10210	COG2363	Small membrane protein
H2Q98_10230	COG0513	Belongs to the DEAD box helicase family
H2Q98_10240	COG0778	Nitroreductase
H2Q98_10270	COG1286	toxin biosynthetic process
H2Q98_10295	COG4783	chaperone-mediated protein folding
H2Q98_10300	COG1610	YqeY-like protein
H2Q98_10355	COG1278	Cold shock
H2Q98_10370	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_10380	COG3243	poly(R)-hydroxyalkanoic acid synthase
H2Q98_10385	COG0786	glutamate:sodium symporter activity
H2Q98_10390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2Q98_10390	COG0475	glutathione-regulated potassium exporter activity
H2Q98_10395	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_10445	COG1309	transcriptional regulator
H2Q98_10455	COG2985	domain, Protein
H2Q98_10470	COG2995	paraquat-inducible protein a
H2Q98_10475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H2Q98_10475	COG3008	intermembrane lipid transfer
H2Q98_10485	COG2351	hydroxyisourate hydrolase activity
H2Q98_10525	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H2Q98_10535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H2Q98_10540	COG0642	Histidine kinase
H2Q98_10545	COG0745	RESPONSE REGULATOR receiver
H2Q98_10560	COG1794	racemase activity, acting on amino acids and derivatives
H2Q98_10600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2Q98_10605	COG2011	ABC-type metal ion transport system permease component
H2Q98_10610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H2Q98_10620	COG0151	Belongs to the GarS family
H2Q98_10630	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H2Q98_10660	COG2308	Evidence 4 Homologs of previously reported genes of
H2Q98_10670	COG1305	Transglutaminase-like
H2Q98_10680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H2Q98_10685	COG0305	Participates in initiation and elongation during chromosome replication
H2Q98_10710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H2Q98_10715	COG1845	cytochrome c oxidase, subunit III
H2Q98_10720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H2Q98_10755	COG0583	DNA-binding transcription factor activity
H2Q98_10770	COG2890	protein-(glutamine-N5) methyltransferase activity
H2Q98_10775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2Q98_10780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2Q98_10795	COG1960	acyl-CoA dehydrogenase activity
H2Q98_10800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2Q98_10815	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H2Q98_10825	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H2Q98_10830	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H2Q98_10835	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H2Q98_10840	COG2205	protein histidine kinase activity
H2Q98_10845	COG0745	RESPONSE REGULATOR receiver
H2Q98_10850	COG0174	glutamine synthetase
H2Q98_10865	COG0477	Major facilitator Superfamily
H2Q98_10870	COG0729	surface antigen
H2Q98_10895	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_10905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2Q98_10910	COG2814	Major facilitator Superfamily
H2Q98_10920	COG0583	DNA-binding transcription factor activity
H2Q98_10935	COG1187	pseudouridine synthase activity
H2Q98_10955	COG0802	atpase or kinase
H2Q98_10960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H2Q98_10970	COG1923	regulation of RNA biosynthetic process
H2Q98_10975	COG0697	spore germination
H2Q98_10990	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2Q98_11000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H2Q98_11005	COG0519	Catalyzes the synthesis of GMP from XMP
H2Q98_11005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H2Q98_11010	COG4302	ethanolamine ammonia-lyase activity
H2Q98_11015	COG4303	Ethanolamine ammonia lyase large subunit
H2Q98_11020	COG0531	amino acid
H2Q98_11040	COG1454	alcohol dehydrogenase
H2Q98_11045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H2Q98_11070	COG0308	aminopeptidase N
H2Q98_11080	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_11130	COG1605	Chorismate mutase
H2Q98_11145	COG4772	TonB-dependent receptor
H2Q98_11150	COG4774	siderophore transport
H2Q98_11205	COG3772	lysozyme
H2Q98_11230	COG0583	DNA-binding transcription factor activity
H2Q98_11255	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_11275	COG0488	(ABC) transporter
H2Q98_11280	COG0589	response to stress
H2Q98_11290	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_11305	COG3135	benzoate transporter
H2Q98_11310	COG1522	sequence-specific DNA binding
H2Q98_11320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H2Q98_11325	COG0583	DNA-binding transcription factor activity
H2Q98_11335	COG0183	Belongs to the thiolase family
H2Q98_11340	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_11345	COG2030	dehydratase
H2Q98_11375	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H2Q98_11385	COG0824	Thioesterase
H2Q98_11390	COG1454	alcohol dehydrogenase
H2Q98_11405	COG1335	isochorismatase
H2Q98_11420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H2Q98_11450	COG0069	glutamate synthase activity
H2Q98_11475	COG2814	Major facilitator Superfamily
H2Q98_11490	COG0511	ligase activity, forming carbon-carbon bonds
H2Q98_11515	COG4264	IucA IucC family
H2Q98_11525	COG4264	IucA IucC family
H2Q98_11530	COG2423	ornithine cyclodeaminase activity
H2Q98_11535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H2Q98_11540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2Q98_11540	COG1116	anion transmembrane transporter activity
H2Q98_11555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2Q98_11555	COG2146	nitrite reductase [NAD(P)H] activity
H2Q98_11560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2Q98_11565	COG0243	molybdopterin cofactor binding
H2Q98_11575	COG0243	molybdopterin cofactor binding
H2Q98_11580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H2Q98_11595	COG0315	cyclic pyranopterin monophosphate synthase activity
H2Q98_11595	COG0521	Mo-molybdopterin cofactor biosynthetic process
H2Q98_11600	COG0303	'Molybdopterin
H2Q98_11610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2Q98_11615	COG0697	spore germination
H2Q98_11640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H2Q98_11710	COG2204	response regulator
H2Q98_11715	COG3852	Histidine kinase
H2Q98_11740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H2Q98_11745	COG0575	Belongs to the CDS family
H2Q98_11780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2Q98_11795	COG2137	regulation of response to DNA damage stimulus
H2Q98_11805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H2Q98_11810	COG1011	Hydrolase
H2Q98_11890	COG1484	DNA-dependent DNA replication
H2Q98_11960	COG3755	Protein conserved in bacteria
H2Q98_12025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H2Q98_12055	COG1522	sequence-specific DNA binding
H2Q98_12065	COG1113	amino acid transport
H2Q98_12080	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_12090	COG0659	secondary active sulfate transmembrane transporter activity
H2Q98_12115	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_12130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H2Q98_12130	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H2Q98_12130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H2Q98_12135	COG1105	Belongs to the carbohydrate kinase PfkB family
H2Q98_12140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2Q98_12140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H2Q98_12160	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H2Q98_12170	COG0024	Methionine aminopeptidase
H2Q98_12175	COG0583	DNA-binding transcription factor activity
H2Q98_12185	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H2Q98_12190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H2Q98_12195	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H2Q98_12195	COG0517	IMP dehydrogenase activity
H2Q98_12220	COG0552	protein localization to endoplasmic reticulum
H2Q98_12245	COG4890	Cyd operon protein YbgT
H2Q98_12250	COG1294	oxidase, subunit
H2Q98_12265	COG1585	Membrane protein implicated in regulation of membrane protease activity
H2Q98_12275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H2Q98_12290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H2Q98_12295	COG0569	domain protein
H2Q98_12300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H2Q98_12330	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H2Q98_12335	COG0542	response to heat
H2Q98_12360	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2Q98_12360	COG1902	pentaerythritol trinitrate reductase activity
H2Q98_12400	COG0148	phosphopyruvate hydratase activity
H2Q98_12405	COG2323	membrane
H2Q98_12415	COG4773	Receptor
H2Q98_12420	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H2Q98_12430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2Q98_12435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2Q98_12440	COG0183	Belongs to the thiolase family
H2Q98_12445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H2Q98_12450	COG0596	Alpha beta hydrolase
H2Q98_12455	COG2271	Major facilitator Superfamily
H2Q98_12460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H2Q98_12465	COG3485	protocatechuate 3,4-dioxygenase
H2Q98_12470	COG3485	protocatechuate 3,4-dioxygenase
H2Q98_12475	COG0710	3-dehydroquinate dehydratase activity
H2Q98_12480	COG3420	alginic acid biosynthetic process
H2Q98_12485	COG3659	wide pore channel activity
H2Q98_12490	COG4993	Dehydrogenase
H2Q98_12500	COG2391	methyltransferase activity
H2Q98_12515	COG1414	Transcriptional regulator
H2Q98_12520	COG0583	DNA-binding transcription factor activity
H2Q98_12525	COG1960	acyl-CoA dehydrogenase activity
H2Q98_12550	COG2814	Major facilitator Superfamily
H2Q98_12560	COG0154	amidase activity
H2Q98_12580	COG4638	Rieske (2fe-2S)
H2Q98_12590	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_12600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2Q98_12610	COG3733	amine oxidase
H2Q98_12620	COG1012	belongs to the aldehyde dehydrogenase family
H2Q98_12625	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2Q98_12630	COG0183	Belongs to the thiolase family
H2Q98_12635	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2Q98_12640	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2Q98_12650	COG4829	muconolactone delta-isomerase
H2Q98_12655	COG4948	Mandelate Racemase Muconate Lactonizing
H2Q98_12660	COG0583	DNA-binding transcription factor activity
H2Q98_12670	COG2186	Transcriptional regulator
H2Q98_12690	COG1012	belongs to the aldehyde dehydrogenase family
H2Q98_12695	COG2351	hydroxyisourate hydrolase activity
H2Q98_12700	COG2233	PERMEase
H2Q98_12710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2Q98_12715	COG2186	Transcriptional regulator
H2Q98_12725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2Q98_12735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2Q98_12755	COG1902	pentaerythritol trinitrate reductase activity
H2Q98_12755	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2Q98_12795	COG1309	transcriptional regulator
H2Q98_12800	COG0583	DNA-binding transcription factor activity
H2Q98_12805	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_12810	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_12815	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_12825	COG1960	acyl-CoA dehydrogenase activity
H2Q98_12835	COG0318	PFAM AMP-dependent synthetase and ligase
H2Q98_12845	COG3328	transposase activity
H2Q98_12880	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_12925	COG0583	DNA-binding transcription factor activity
H2Q98_12950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H2Q98_12955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H2Q98_12970	COG2831	hemolysin activation secretion protein
H2Q98_13035	COG1120	ATPase activity
H2Q98_13045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H2Q98_13095	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H2Q98_13155	COG4628	conserved protein (DUF2132)
H2Q98_13255	COG3539	Fimbrial protein
H2Q98_13280	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H2Q98_13290	COG0753	catalase activity
H2Q98_13310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2Q98_13320	COG2205	protein histidine kinase activity
H2Q98_13325	COG0745	RESPONSE REGULATOR receiver
H2Q98_13330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2Q98_13335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2Q98_13390	COG3433	isochorismatase activity
H2Q98_13390	COG1535	isochorismatase
H2Q98_13395	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_13400	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H2Q98_13405	COG4149	molybdate abc transporter
H2Q98_13410	COG0725	ABC transporter, periplasmic molybdate-binding protein
H2Q98_13420	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_13430	COG4638	Rieske (2fe-2S)
H2Q98_13435	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H2Q98_13440	COG0543	2 iron, 2 sulfur cluster binding
H2Q98_13440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2Q98_13455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2Q98_13465	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_13485	COG2207	Transcriptional regulator
H2Q98_13490	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_13495	COG2610	gluconate transmembrane transporter activity
H2Q98_13515	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_13530	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_13545	COG0583	DNA-binding transcription factor activity
H2Q98_13560	COG2031	fatty acid transporter
H2Q98_13565	COG0183	Belongs to the thiolase family
H2Q98_13570	COG0583	DNA-binding transcription factor activity
H2Q98_13575	COG0583	DNA-binding transcription factor activity
H2Q98_13590	COG1027	Aspartate ammonia-lyase
H2Q98_13600	COG0477	Major facilitator Superfamily
H2Q98_13610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H2Q98_13615	COG1733	regulation of RNA biosynthetic process
H2Q98_13620	COG2207	Transcriptional regulator
H2Q98_13620	COG3708	Transcriptional regulator
H2Q98_13635	COG0730	response to heat
H2Q98_13655	COG3781	membrane
H2Q98_13660	COG1063	alcohol dehydrogenase
H2Q98_13670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2Q98_13675	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2Q98_13680	COG0022	dehydrogenase e1 component
H2Q98_13685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H2Q98_13690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H2Q98_13700	COG3328	transposase activity
H2Q98_13715	COG3706	GGDEF domain
H2Q98_13725	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_13740	COG0133	tryptophan synthase activity
H2Q98_13750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H2Q98_13780	COG0583	DNA-binding transcription factor activity
H2Q98_13785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H2Q98_13795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H2Q98_13855	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2Q98_13860	COG4773	Receptor
H2Q98_13885	COG0730	response to heat
H2Q98_13890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H2Q98_13910	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H2Q98_13925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H2Q98_13935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H2Q98_13950	COG1960	acyl-CoA dehydrogenase activity
H2Q98_13955	COG1960	acyl-CoA dehydrogenase activity
H2Q98_13960	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2Q98_13965	COG2207	Transcriptional regulator
H2Q98_13970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H2Q98_13975	COG0776	regulation of translation
H2Q98_14000	COG0822	iron-sulfur transferase activity
H2Q98_14005	COG0316	Belongs to the HesB IscA family
H2Q98_14035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H2Q98_14055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H2Q98_14060	COG0702	epimerase
H2Q98_14100	COG0601	transmembrane transport
H2Q98_14105	COG0339	signal peptide processing
H2Q98_14110	COG4166	transmembrane transport
H2Q98_14155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H2Q98_14160	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H2Q98_14175	COG2431	L-lysine efflux transmembrane transporter activity
H2Q98_14190	COG0776	regulation of translation
H2Q98_14255	COG0084	hydrolase, TatD family'
H2Q98_14275	COG1663	tetraacyldisaccharide 4'-kinase activity
H2Q98_14280	COG1132	(ABC) transporter
H2Q98_14290	COG0811	peptide transport
H2Q98_14295	COG1475	DNA binding
H2Q98_14300	COG1192	Involved in chromosome partitioning
H2Q98_14310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H2Q98_14315	COG3178	'Phosphotransferase
H2Q98_14325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H2Q98_14350	COG0424	maF-like protein
H2Q98_14355	COG2850	peptidyl-arginine hydroxylation
H2Q98_14365	COG0640	Transcriptional regulator
H2Q98_14375	COG3619	membrane
H2Q98_14380	COG3122	Protein conserved in bacteria
H2Q98_14385	COG1132	(ABC) transporter
H2Q98_14405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H2Q98_14410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2Q98_14420	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H2Q98_14420	COG0506	proline dehydrogenase activity
H2Q98_14420	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H2Q98_14430	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_14450	COG3698	Phosphodiester glycosidase
H2Q98_14460	COG2353	YceI-like domain
H2Q98_14470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H2Q98_14515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H2Q98_14515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H2Q98_14540	COG3539	Fimbrial protein
H2Q98_14560	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_14575	COG0583	DNA-binding transcription factor activity
H2Q98_14580	COG0697	spore germination
H2Q98_14590	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H2Q98_14600	COG0583	DNA-binding transcription factor activity
H2Q98_14615	COG1309	transcriptional regulator
H2Q98_14630	COG1522	sequence-specific DNA binding
H2Q98_14640	COG1126	abc transporter atp-binding protein
H2Q98_14645	COG0765	amino acid transport
H2Q98_14650	COG0765	amino acid transport
H2Q98_14680	COG1464	Belongs to the NlpA lipoprotein family
H2Q98_14690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H2Q98_14695	COG2011	ABC-type metal ion transport system permease component
H2Q98_14700	COG0012	GTP binding
H2Q98_14725	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H2Q98_14760	COG2207	Transcriptional regulator
H2Q98_14760	COG1917	Cupin 2, conserved barrel domain protein
H2Q98_14765	COG0386	Belongs to the glutathione peroxidase family
H2Q98_14775	COG0436	Aminotransferase
H2Q98_14780	COG1301	dicarboxylic acid transport
H2Q98_14815	COG3634	alkyl hydroperoxide reductase activity
H2Q98_14830	COG0583	DNA-binding transcription factor activity
H2Q98_14835	COG0431	NADPH-dependent FMN reductase
H2Q98_14840	COG0798	PFAM Bile acid sodium symporter
H2Q98_14850	COG0640	Transcriptional regulator
H2Q98_14865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H2Q98_14875	COG0583	DNA-binding transcription factor activity
H2Q98_14905	COG1271	oxidase subunit
H2Q98_14910	COG1294	oxidase, subunit
H2Q98_14920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2Q98_14940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H2Q98_14960	COG3052	prosthetic group binding
H2Q98_14965	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H2Q98_14990	COG1346	cytolysis
H2Q98_15000	COG0583	DNA-binding transcription factor activity
H2Q98_15005	COG0625	glutathione transferase activity
H2Q98_15010	COG0625	glutathione transferase activity
H2Q98_15030	COG0583	DNA-binding transcription factor activity
H2Q98_15045	COG1045	serine acetyltransferase
H2Q98_15050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2Q98_15055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H2Q98_15060	COG1280	lysine exporter protein (LysE YggA)
H2Q98_15075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2Q98_15080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2Q98_15090	COG0765	amino acid transport
H2Q98_15095	COG0765	amino acid transport
H2Q98_15115	COG2205	protein histidine kinase activity
H2Q98_15115	COG0784	Response regulator, receiver
H2Q98_15135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H2Q98_15155	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_15175	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_15205	COG0583	DNA-binding transcription factor activity
H2Q98_15215	COG2814	Major facilitator Superfamily
H2Q98_15230	COG0318	PFAM AMP-dependent synthetase and ligase
H2Q98_15235	COG1309	transcriptional regulator
H2Q98_15240	COG1960	acyl-CoA dehydrogenase activity
H2Q98_15245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H2Q98_15250	COG1024	Enoyl-CoA hydratase
H2Q98_15255	COG4770	biotin carboxylase activity
H2Q98_15265	COG0583	DNA-binding transcription factor activity
H2Q98_15280	COG1960	acyl-CoA dehydrogenase activity
H2Q98_15290	COG2814	Major facilitator Superfamily
H2Q98_15300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2Q98_15305	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2Q98_15310	COG2814	Major facilitator Superfamily
H2Q98_15315	COG1960	acyl-CoA dehydrogenase activity
H2Q98_15320	COG1024	Enoyl-CoA hydratase
H2Q98_15325	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_15330	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2Q98_15335	COG0183	Belongs to the thiolase family
H2Q98_15345	COG2814	Major facilitator Superfamily
H2Q98_15355	COG1024	Enoyl-CoA hydratase
H2Q98_15370	COG1960	acyl-CoA dehydrogenase activity
H2Q98_15375	COG2814	Major facilitator Superfamily
H2Q98_15380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H2Q98_15385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H2Q98_15400	COG3842	ATPase activity
H2Q98_15405	COG1840	ABC-type Fe3 transport system, periplasmic component
H2Q98_15435	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_15445	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_15450	COG0583	DNA-binding transcription factor activity
H2Q98_15455	COG2050	protein possibly involved in aromatic compounds catabolism
H2Q98_15465	COG3327	negative regulation of DNA-templated transcription, initiation
H2Q98_15470	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H2Q98_15475	COG0183	Belongs to the thiolase family
H2Q98_15480	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2Q98_15485	COG1024	Enoyl-CoA hydratase
H2Q98_15490	COG1024	Enoyl-CoA hydratase
H2Q98_15495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2Q98_15500	COG2151	metal-sulfur cluster biosynthetic enzyme
H2Q98_15505	COG3396	Phenylacetate-CoA oxygenase
H2Q98_15510	COG3460	Phenylacetate-CoA oxygenase
H2Q98_15515	COG3396	Phenylacetate-CoA oxygenase
H2Q98_15520	COG1012	belongs to the aldehyde dehydrogenase family
H2Q98_15520	COG2030	dehydratase
H2Q98_15525	COG1760	l-serine dehydratase
H2Q98_15540	COG0789	Transcriptional regulator
H2Q98_15550	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H2Q98_15555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2Q98_15570	COG2807	transmembrane transport
H2Q98_15575	COG0590	tRNA wobble adenosine to inosine editing
H2Q98_15580	COG0666	response to abiotic stimulus
H2Q98_15625	COG1063	alcohol dehydrogenase
H2Q98_15630	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2Q98_15665	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_15675	COG2831	hemolysin activation secretion protein
H2Q98_15680	COG0038	chloride channel
H2Q98_15685	COG4770	biotin carboxylase activity
H2Q98_15705	COG1914	H( )-stimulated, divalent metal cation uptake system
H2Q98_15720	COG1595	DNA-templated transcription, initiation
H2Q98_15730	COG3220	belongs to the UPF0276 family
H2Q98_15780	COG0531	amino acid
H2Q98_15785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H2Q98_15800	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2Q98_15815	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H2Q98_15825	COG4122	O-methyltransferase activity
H2Q98_15855	COG1538	Outer membrane efflux protein
H2Q98_15860	COG1137	ATPase activity
H2Q98_15865	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H2Q98_15875	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H2Q98_15895	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_15915	COG2814	Major facilitator Superfamily
H2Q98_15925	COG0668	transmembrane transport
H2Q98_15970	COG1309	transcriptional regulator
H2Q98_15980	COG2226	methyltransferase
H2Q98_15985	COG1011	Hydrolase
H2Q98_16010	COG1278	Cold shock
H2Q98_16015	COG1560	Kdo2-lipid A biosynthetic process
H2Q98_16020	COG1280	lysine exporter protein (LysE YggA)
H2Q98_16055	COG1570	exodeoxyribonuclease VII activity
H2Q98_16135	COG2871	sodium ion transport
H2Q98_16145	COG0583	DNA-binding transcription factor activity
H2Q98_16155	COG4638	Rieske (2fe-2S)
H2Q98_16160	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H2Q98_16165	COG0543	2 iron, 2 sulfur cluster binding
H2Q98_16165	COG0633	Ferredoxin
H2Q98_16170	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_16175	COG3135	benzoate transporter
H2Q98_16185	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_16205	COG1643	Atp-dependent helicase
H2Q98_16230	COG3634	alkyl hydroperoxide reductase activity
H2Q98_16250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H2Q98_16255	COG0625	glutathione transferase activity
H2Q98_16265	COG2885	chlorophyll binding
H2Q98_16290	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_16305	COG0542	response to heat
H2Q98_16320	COG1765	OsmC-like protein
H2Q98_16335	COG0667	Aldo Keto reductase
H2Q98_16350	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H2Q98_16360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H2Q98_16370	COG0582	viral genome integration into host DNA
H2Q98_16385	COG3293	Transposase
H2Q98_16390	COG1063	alcohol dehydrogenase
H2Q98_16555	COG0527	aspartate kinase activity
H2Q98_16565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H2Q98_16575	COG3038	cytochrome b561
H2Q98_16580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H2Q98_16585	COG2252	PERMEase
H2Q98_16595	COG1741	Belongs to the pirin family
H2Q98_16600	COG1309	transcriptional regulator
H2Q98_16615	COG2072	flavoprotein involved in K transport
H2Q98_16620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H2Q98_16625	COG0583	DNA-binding transcription factor activity
H2Q98_16640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H2Q98_16670	COG1944	ATP diphosphatase activity
H2Q98_16690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H2Q98_16705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2Q98_16715	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_16725	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H2Q98_16730	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_16745	COG2814	Major facilitator Superfamily
H2Q98_16750	COG1024	Enoyl-CoA hydratase
H2Q98_16765	COG1960	acyl-CoA dehydrogenase activity
H2Q98_16790	COG2186	Transcriptional regulator
H2Q98_16795	COG1012	belongs to the aldehyde dehydrogenase family
H2Q98_16805	COG4948	Mandelate Racemase Muconate Lactonizing
H2Q98_16810	COG2271	Major facilitator Superfamily
H2Q98_16815	COG2721	sulfolactate sulfo-lyase activity
H2Q98_16820	COG0697	spore germination
H2Q98_16840	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_16860	COG1012	belongs to the aldehyde dehydrogenase family
H2Q98_16880	COG0531	amino acid
H2Q98_16890	COG1113	amino acid transport
H2Q98_16925	COG2801	Transposase and inactivated derivatives
H2Q98_16935	COG4269	membrane
H2Q98_16955	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2Q98_16955	COG1902	pentaerythritol trinitrate reductase activity
H2Q98_16965	COG3706	GGDEF domain
H2Q98_16965	COG4251	negative regulation of phosphorylation
H2Q98_16965	COG5001	Diguanylate cyclase
H2Q98_16965	COG2203	Gaf domain
H2Q98_16975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H2Q98_17000	COG4172	Belongs to the ABC transporter superfamily
H2Q98_17005	COG4239	(ABC) transporter, permease
H2Q98_17010	COG4174	ABC transporter (Permease)
H2Q98_17015	COG4166	transmembrane transport
H2Q98_17020	COG0741	lytic transglycosylase activity
H2Q98_17020	COG1388	LysM domain
H2Q98_17065	COG0583	DNA-binding transcription factor activity
H2Q98_17070	COG1279	arginine transmembrane transporter activity
H2Q98_17090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2Q98_17095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2Q98_17100	COG0006	proline dipeptidase activity
H2Q98_17140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H2Q98_17155	COG3384	dioxygenase
H2Q98_17165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H2Q98_17170	COG2878	Part of a membrane complex involved in electron transport
H2Q98_17175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H2Q98_17200	COG0768	penicillin binding
H2Q98_17205	COG0742	ribosomal rna small subunit methyltransferase
H2Q98_17220	COG0830	nickel cation binding
H2Q98_17230	COG0804	urea catabolic process
H2Q98_17260	COG3015	lipoprotein NlpE involved in copper resistance
H2Q98_17275	COG1253	flavin adenine dinucleotide binding
H2Q98_17280	COG2851	Citrate transporter
H2Q98_17330	COG1773	rubredoxin
H2Q98_17335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2Q98_17340	COG2267	carboxylic ester hydrolase activity
H2Q98_17345	COG0583	DNA-binding transcription factor activity
H2Q98_17375	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H2Q98_17380	COG4181	ATPase activity
H2Q98_17425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H2Q98_17445	COG0306	phosphate transporter
H2Q98_17470	COG2223	nitrite transmembrane transporter activity
H2Q98_17475	COG2207	Transcriptional regulator
H2Q98_17480	COG2066	Belongs to the glutaminase family
H2Q98_17485	COG0242	peptide deformylase activity
H2Q98_17490	COG0477	Major facilitator Superfamily
H2Q98_17500	COG0028	Belongs to the TPP enzyme family
H2Q98_17515	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_17520	COG2267	carboxylic ester hydrolase activity
H2Q98_17530	COG2271	Major facilitator Superfamily
H2Q98_17545	COG1028	Short-chain dehydrogenase reductase Sdr
H2Q98_17565	COG1414	Transcriptional regulator
H2Q98_17580	COG1024	Enoyl-CoA hydratase
H2Q98_17590	COG1215	transferase activity, transferring glycosyl groups
H2Q98_17595	COG1649	PFAM Uncharacterised BCR, COG1649
H2Q98_17595	COG0726	polysaccharide deacetylase
H2Q98_17605	COG4681	YaeQ
H2Q98_17615	COG0523	cobalamin synthesis protein
H2Q98_17625	COG1607	acyl-coa hydrolase
H2Q98_17635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2Q98_17640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2Q98_17645	COG1309	transcriptional regulator
H2Q98_17670	COG2040	homocysteine
H2Q98_17675	COG0531	amino acid
H2Q98_17730	COG1595	DNA-templated transcription, initiation
H2Q98_17740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2Q98_17745	COG0477	Major facilitator Superfamily
H2Q98_17780	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_17815	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_17825	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_17920	COG1196	nuclear chromosome segregation
H2Q98_17920	COG0739	heme binding
H2Q98_17920	COG0741	lytic transglycosylase activity
H2Q98_17930	COG1598	PFAM Uncharacterised protein family UPF0150
H2Q98_18235	COG0405	Gamma-glutamyltransferase
H2Q98_18240	COG2814	Major facilitator Superfamily
H2Q98_18250	COG2050	protein possibly involved in aromatic compounds catabolism
H2Q98_18265	COG1090	epimerase
H2Q98_18285	COG0420	3'-5' exonuclease activity
H2Q98_18310	COG0735	belongs to the Fur family
H2Q98_18315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H2Q98_18320	COG2914	Belongs to the UPF0125 (RnfH) family
H2Q98_18335	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_18340	COG0121	glutamine amidotransferase
H2Q98_18355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H2Q98_18365	COG0210	DNA helicase
H2Q98_18370	COG2885	chlorophyll binding
H2Q98_18375	COG0204	Acyl-transferase
H2Q98_18390	COG2894	cell division
H2Q98_18410	COG1280	lysine exporter protein (LysE YggA)
H2Q98_18415	COG1674	ftsk spoiiie
H2Q98_18420	COG0492	ferredoxin-NADP+ reductase activity
H2Q98_18425	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H2Q98_18435	COG0456	acetyltransferase
H2Q98_18450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H2Q98_18455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H2Q98_18465	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H2Q98_18490	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H2Q98_18490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H2Q98_18510	COG1012	belongs to the aldehyde dehydrogenase family
H2Q98_18515	COG4638	Rieske (2fe-2S)
H2Q98_18530	COG0473	3-isopropylmalate dehydrogenase activity
H2Q98_18535	COG0583	DNA-binding transcription factor activity
H2Q98_18555	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H2Q98_18590	COG0358	DNA primase activity
H2Q98_18605	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H2Q98_18635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H2Q98_18665	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H2Q98_18675	COG0351	phosphomethylpyrimidine kinase
H2Q98_18675	COG0352	thiamine-phosphate diphosphorylase activity
H2Q98_18675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H2Q98_18680	COG1652	LysM domain
H2Q98_18705	COG1399	metal-binding, possibly nucleic acid-binding protein
H2Q98_18710	COG3101	peptidyl-lysine hydroxylation
H2Q98_18715	COG0009	L-threonylcarbamoyladenylate synthase
H2Q98_18720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H2Q98_18725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H2Q98_18740	COG4106	trans-aconitate 2-methyltransferase activity
H2Q98_18755	COG2226	methyltransferase
H2Q98_18755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2Q98_18755	COG0596	Alpha beta hydrolase
H2Q98_18760	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_18770	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H2Q98_18775	COG2223	nitrite transmembrane transporter activity
H2Q98_18800	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_18815	COG3328	transposase activity
H2Q98_18835	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_18865	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H2Q98_18880	COG1196	nuclear chromosome segregation
H2Q98_18890	COG0730	response to heat
H2Q98_18905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H2Q98_18915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H2Q98_18960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H2Q98_18965	COG0489	protein tyrosine kinase activity
H2Q98_18975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2Q98_18975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2Q98_19010	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H2Q98_19015	COG2081	HI0933 family
H2Q98_19025	COG0668	transmembrane transport
H2Q98_19045	COG0583	DNA-binding transcription factor activity
H2Q98_19065	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H2Q98_19070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H2Q98_19100	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H2Q98_19125	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_19130	COG2199	diguanylate cyclase activity
H2Q98_19140	COG2205	protein histidine kinase activity
H2Q98_19145	COG0745	RESPONSE REGULATOR receiver
H2Q98_19160	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H2Q98_19185	COG2826	transposase and inactivated derivatives, IS30 family
H2Q98_19230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2Q98_19245	COG0583	DNA-binding transcription factor activity
H2Q98_19265	COG1473	amidohydrolase
H2Q98_19295	COG0583	DNA-binding transcription factor activity
H2Q98_19310	COG0583	DNA-binding transcription factor activity
H2Q98_19315	COG1053	succinate dehydrogenase
H2Q98_19330	COG1309	transcriptional regulator
H2Q98_19340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H2Q98_19345	COG2814	Major facilitator Superfamily
H2Q98_19350	COG1960	acyl-CoA dehydrogenase activity
H2Q98_19355	COG0583	DNA-binding transcription factor activity
H2Q98_19360	COG1063	alcohol dehydrogenase
H2Q98_19370	COG3328	transposase activity
H2Q98_19400	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H2Q98_19405	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H2Q98_19410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H2Q98_19430	COG2132	Multicopper oxidase
H2Q98_19440	COG0561	phosphatase activity
H2Q98_19445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H2Q98_19470	COG1214	PFAM Peptidase M22, glycoprotease
H2Q98_19530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H2Q98_19535	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H2Q98_19540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine