locus-tag	class	description
NIY04_00010	COG0592	DNA-directed DNA polymerase activity
NIY04_00020	COG0187	DNA topoisomerase II activity
NIY04_00030	COG0586	Pfam SNARE associated Golgi protein
NIY04_00035	COG0488	(ABC) transporter
NIY04_00060	COG0596	Alpha beta hydrolase
NIY04_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NIY04_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIY04_00110	COG0733	neurotransmitter:sodium symporter activity
NIY04_00150	COG2233	PERMEase
NIY04_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY04_00200	COG2814	Major facilitator Superfamily
NIY04_00205	COG0656	L-ascorbic acid biosynthetic process
NIY04_00210	COG0583	DNA-binding transcription factor activity
NIY04_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY04_00230	COG1064	alcohol dehydrogenase
NIY04_00235	COG2818	Glycosylase
NIY04_00250	COG1194	a g-specific adenine glycosylase
NIY04_00270	COG2983	Belongs to the UPF0260 family
NIY04_00275	COG2133	pyrroloquinoline quinone binding
NIY04_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NIY04_00285	COG2116	formate transmembrane transporter activity
NIY04_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY04_00310	COG1335	isochorismatase
NIY04_00315	COG0385	Bile acid
NIY04_00320	COG0534	Mate efflux family protein
NIY04_00325	COG1683	Conserved Protein
NIY04_00345	COG0625	glutathione transferase activity
NIY04_00355	COG1113	amino acid transport
NIY04_00365	COG0523	cobalamin synthesis protein
NIY04_00375	COG2188	Transcriptional regulator
NIY04_00405	COG0010	Belongs to the arginase family
NIY04_00425	COG1280	lysine exporter protein (LysE YggA)
NIY04_00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NIY04_00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NIY04_00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NIY04_00500	COG0753	catalase activity
NIY04_00550	COG0534	Mate efflux family protein
NIY04_00555	COG0436	Aminotransferase
NIY04_00560	COG2733	membrane
NIY04_00575	COG2918	glutathione biosynthetic process
NIY04_00590	COG1388	LysM domain
NIY04_00590	COG1705	Flagellar rod assembly protein muramidase FlgJ
NIY04_00625	COG3150	esterase
NIY04_00635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
NIY04_00645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY04_00655	COG2233	PERMEase
NIY04_00660	COG2351	hydroxyisourate hydrolase activity
NIY04_00695	COG3706	GGDEF domain
NIY04_00710	COG1393	Belongs to the ArsC family
NIY04_00715	COG0708	Exodeoxyribonuclease III
NIY04_00740	COG0189	ligase activity
NIY04_00760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NIY04_00770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIY04_00785	COG4942	peptidase
NIY04_00795	COG0508	dehydrogenase complex catalyzes the overall conversion of
NIY04_00805	COG2119	membrane
NIY04_00810	COG4774	siderophore transport
NIY04_00815	COG0426	domain, Protein
NIY04_00815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY04_00840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NIY04_00860	COG1902	pentaerythritol trinitrate reductase activity
NIY04_00865	COG1519	Transferase
NIY04_00875	COG0668	transmembrane transport
NIY04_00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY04_00890	COG1335	isochorismatase
NIY04_00895	COG1522	sequence-specific DNA binding
NIY04_00920	COG2205	protein histidine kinase activity
NIY04_00920	COG2198	Histidine kinase
NIY04_00920	COG0784	Response regulator, receiver
NIY04_00925	COG3162	membrane
NIY04_00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIY04_00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY04_00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NIY04_00960	COG1309	transcriptional regulator
NIY04_00980	COG0351	phosphomethylpyrimidine kinase
NIY04_00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIY04_00980	COG0352	thiamine-phosphate diphosphorylase activity
NIY04_00990	COG2814	Major facilitator Superfamily
NIY04_01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NIY04_01015	COG1113	amino acid transport
NIY04_01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIY04_01030	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_01040	COG1335	isochorismatase
NIY04_01080	COG2814	Major facilitator Superfamily
NIY04_01085	COG0583	DNA-binding transcription factor activity
NIY04_01130	COG1733	regulation of RNA biosynthetic process
NIY04_01160	COG1733	regulation of RNA biosynthetic process
NIY04_01165	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY04_01185	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NIY04_01190	COG2207	Transcriptional regulator
NIY04_01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NIY04_01260	COG2329	Antibiotic biosynthesis monooxygenase
NIY04_01290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIY04_01320	COG0427	acetyl-CoA hydrolase
NIY04_01345	COG0659	secondary active sulfate transmembrane transporter activity
NIY04_01350	COG4221	oxidoreductase activity
NIY04_01375	COG0488	(ABC) transporter
NIY04_01440	COG0833	amino acid
NIY04_01485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIY04_01490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NIY04_01505	COG2226	methyltransferase
NIY04_01555	COG0070	glutamate synthase
NIY04_01555	COG0069	glutamate synthase activity
NIY04_01555	COG0067	glutamate synthase
NIY04_01560	COG0493	'glutamate synthase
NIY04_01570	COG1704	LemA family
NIY04_01575	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NIY04_01585	COG4969	Belongs to the N-Me-Phe pilin family
NIY04_01590	COG3307	-O-antigen
NIY04_01610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIY04_01625	COG0194	GDP metabolic process
NIY04_01675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIY04_01695	COG5380	lipid catabolic process
NIY04_01700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIY04_01725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NIY04_01730	COG0277	FAD linked oxidase domain protein
NIY04_01740	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NIY04_01745	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY04_01760	COG1289	transmembrane transporter activity
NIY04_01770	COG0628	permease
NIY04_01775	COG1192	Involved in chromosome partitioning
NIY04_01805	COG0833	amino acid
NIY04_01810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NIY04_01815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NIY04_01825	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_01865	COG0583	DNA-binding transcription factor activity
NIY04_01915	COG0517	IMP dehydrogenase activity
NIY04_01920	COG1983	PspC domain protein
NIY04_01930	COG1960	acyl-CoA dehydrogenase activity
NIY04_01945	COG0408	coproporphyrinogen oxidase activity
NIY04_01965	COG0513	Belongs to the DEAD box helicase family
NIY04_01975	COG1127	ABC transporter
NIY04_01980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NIY04_01990	COG2854	intermembrane phospholipid transfer
NIY04_02000	COG0598	Magnesium transport protein CorA
NIY04_02010	COG0494	nUDIX hydrolase
NIY04_02015	COG1040	competence protein
NIY04_02020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIY04_02040	COG1946	Acyl-CoA thioesterase
NIY04_02045	COG1301	dicarboxylic acid transport
NIY04_02060	COG1959	2 iron, 2 sulfur cluster binding
NIY04_02065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY04_02065	COG1017	nitric oxide dioxygenase activity
NIY04_02075	COG0433	COG0433 Predicted ATPase
NIY04_02080	COG0626	cystathionine gamma-synthase activity
NIY04_02235	COG1960	acyl-CoA dehydrogenase activity
NIY04_02240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NIY04_02270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NIY04_02275	COG0339	signal peptide processing
NIY04_02280	COG0557	exoribonuclease II activity
NIY04_02325	COG0179	Fumarylacetoacetate (FAA) hydrolase
NIY04_02330	COG2169	Transcriptional regulator
NIY04_02335	COG0697	spore germination
NIY04_02340	COG1295	ribonuclease BN
NIY04_02375	COG1702	phosphate starvation-inducible protein PhoH
NIY04_02385	COG0739	heme binding
NIY04_02385	COG0741	lytic transglycosylase activity
NIY04_02385	COG1196	nuclear chromosome segregation
NIY04_02415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NIY04_02420	COG1183	phosphatidylcholine synthase activity
NIY04_02465	COG1960	acyl-CoA dehydrogenase activity
NIY04_02470	COG1309	transcriptional regulator
NIY04_02485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NIY04_02490	COG1960	acyl-CoA dehydrogenase activity
NIY04_02510	COG2969	positive regulation of protein catabolic process
NIY04_02520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NIY04_02530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NIY04_02535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NIY04_02540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NIY04_02560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIY04_02570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIY04_02585	COG2199	diguanylate cyclase activity
NIY04_02645	COG1607	acyl-coa hydrolase
NIY04_02675	COG3013	Belongs to the UPF0304 family
NIY04_02755	COG2205	protein histidine kinase activity
NIY04_02770	COG2132	Multicopper oxidase
NIY04_02795	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIY04_02845	COG0582	viral genome integration into host DNA
NIY04_02870	COG2350	Protein conserved in bacteria
NIY04_02880	COG0613	PHP domain protein
NIY04_02885	COG3781	membrane
NIY04_02895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIY04_02900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NIY04_02910	COG1862	Preprotein translocase
NIY04_02940	COG0582	viral genome integration into host DNA
NIY04_02960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NIY04_02975	COG2205	protein histidine kinase activity
NIY04_02980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NIY04_03000	COG0726	polysaccharide deacetylase
NIY04_03005	COG0463	Glycosyl transferase, family 2
NIY04_03010	COG0438	transferase activity, transferring glycosyl groups
NIY04_03025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NIY04_03075	COG1960	acyl-CoA dehydrogenase activity
NIY04_03080	COG1960	acyl-CoA dehydrogenase activity
NIY04_03090	COG2205	protein histidine kinase activity
NIY04_03095	COG0745	RESPONSE REGULATOR receiver
NIY04_03100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NIY04_03120	COG2096	Adenosyltransferase
NIY04_03125	COG4206	TonB-dependent receptor
NIY04_03170	COG0285	dihydrofolate synthase activity
NIY04_03190	COG0450	alkyl hydroperoxide reductase
NIY04_03205	COG0477	Major facilitator Superfamily
NIY04_03210	COG1272	protein, Hemolysin III
NIY04_03220	COG2153	protein acetylation
NIY04_03240	COG0183	Belongs to the thiolase family
NIY04_03245	COG2207	Transcriptional regulator
NIY04_03265	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY04_03285	COG0183	Belongs to the thiolase family
NIY04_03305	COG1690	Belongs to the RtcB family
NIY04_03310	COG0833	amino acid
NIY04_03320	COG2233	PERMEase
NIY04_03325	COG1217	gtp-binding protein TYPA
NIY04_03350	COG2094	Belongs to the DNA glycosylase MPG family
NIY04_03355	COG4772	TonB-dependent receptor
NIY04_03360	COG1902	pentaerythritol trinitrate reductase activity
NIY04_03375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY04_03380	COG0354	folic acid binding
NIY04_03390	COG3189	MarR family transcriptional regulator
NIY04_03395	COG2824	Alkylphosphonate utilization operon protein PhnA
NIY04_03400	COG3422	double-strand break repair
NIY04_03440	COG0840	transmembrane signaling receptor activity
NIY04_03460	COG5510	response to toxic substance
NIY04_03470	COG2832	Protein of unknown function (DUF454)
NIY04_03475	COG1376	ErfK ybiS ycfS ynhG family protein
NIY04_03515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NIY04_03525	COG1289	transmembrane transporter activity
NIY04_03530	COG2814	Major facilitator Superfamily
NIY04_03550	COG1115	amino acid carrier protein
NIY04_03555	COG1752	Esterase of the alpha-beta hydrolase superfamily
NIY04_03560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIY04_03565	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
NIY04_03570	COG3590	peptidase
NIY04_03595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIY04_03605	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIY04_03610	COG1077	Cell shape determining protein MreB Mrl
NIY04_03615	COG1792	Involved in formation and maintenance of cell shape
NIY04_03620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NIY04_03625	COG0424	maF-like protein
NIY04_03630	COG1530	ribonuclease E activity
NIY04_03640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY04_03650	COG0560	Phosphoserine phosphatase
NIY04_03660	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY04_03685	COG2207	Transcriptional regulator
NIY04_03705	COG1113	amino acid transport
NIY04_03710	COG2828	Protein conserved in bacteria
NIY04_03715	COG0142	geranyltranstransferase activity
NIY04_03720	COG2315	Protein conserved in bacteria
NIY04_03735	COG1752	Esterase of the alpha-beta hydrolase superfamily
NIY04_03755	COG2194	sulfuric ester hydrolase activity
NIY04_03760	COG0745	RESPONSE REGULATOR receiver
NIY04_03765	COG0642	Histidine kinase
NIY04_03775	COG0004	ammonium transporteR
NIY04_03780	COG0583	DNA-binding transcription factor activity
NIY04_03800	COG0525	valine-tRNA ligase activity
NIY04_03810	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_03820	COG0393	Putative heavy-metal-binding
NIY04_03825	COG0393	Putative heavy-metal-binding
NIY04_03830	COG1538	Outer membrane efflux protein
NIY04_03840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY04_03845	COG0671	phosphoesterase, PA-phosphatase related
NIY04_03875	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NIY04_03890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NIY04_03890	COG1648	precorrin-2 dehydrogenase activity
NIY04_03895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NIY04_03900	COG1733	regulation of RNA biosynthetic process
NIY04_03910	COG0531	amino acid
NIY04_03925	COG0321	lipoyl(octanoyl) transferase activity
NIY04_03930	COG2921	Belongs to the UPF0250 family
NIY04_03970	COG2009	succinate dehydrogenase
NIY04_03975	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NIY04_03980	COG1053	succinate dehydrogenase
NIY04_03985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NIY04_04010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY04_04030	COG2354	Protein conserved in bacteria
NIY04_04035	COG2321	neutral zinc metallopeptidase
NIY04_04055	COG2843	Capsule synthesis protein
NIY04_04070	COG0589	response to stress
NIY04_04080	COG0251	oxidation-reduction process
NIY04_04100	COG0505	Belongs to the CarA family
NIY04_04125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIY04_04130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NIY04_04180	COG0477	Major facilitator Superfamily
NIY04_04185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIY04_04200	COG1597	lipid kinase activity
NIY04_04205	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NIY04_04225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY04_04230	COG0584	glycerophosphoryl diester phosphodiesterase
NIY04_04250	COG0741	lytic transglycosylase activity
NIY04_04270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NIY04_04285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY04_04295	COG3811	Belongs to the UPF0386 family
NIY04_04355	COG0778	Nitroreductase
NIY04_04370	COG1929	Belongs to the glycerate kinase type-1 family
NIY04_04375	COG0243	molybdopterin cofactor binding
NIY04_04380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NIY04_04385	COG3339	Conserved Protein
NIY04_04395	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NIY04_04410	COG1113	amino acid transport
NIY04_04420	COG0019	diaminopimelate decarboxylase activity
NIY04_04430	COG1280	lysine exporter protein (LysE YggA)
NIY04_04435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NIY04_04465	COG0463	Glycosyl transferase, family 2
NIY04_04485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY04_04520	COG4591	ABC-type transport system involved in lipoprotein release permease component
NIY04_04525	COG1136	(ABC) transporter
NIY04_04530	COG0658	competence protein
NIY04_04530	COG2333	competence protein COMEC
NIY04_04540	COG0616	signal peptide processing
NIY04_04540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NIY04_04545	COG0596	Alpha beta hydrolase
NIY04_04550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NIY04_04560	COG0628	permease
NIY04_04595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIY04_04615	COG0823	Involved in the tonB-independent uptake of proteins
NIY04_04635	COG0824	Thioesterase
NIY04_04640	COG1473	amidohydrolase
NIY04_04660	COG0047	phosphoribosylformylglycinamidine synthase activity
NIY04_04660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIY04_04685	COG1169	isochorismate synthase
NIY04_04695	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_04700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY04_04715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY04_04720	COG1021	2,3-dihydroxybenzoate-AMP ligase
NIY04_04725	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NIY04_04730	COG0019	diaminopimelate decarboxylase activity
NIY04_04750	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NIY04_04755	COG4774	siderophore transport
NIY04_04770	COG0534	Mate efflux family protein
NIY04_04780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY04_04855	COG1024	Enoyl-CoA hydratase
NIY04_04860	COG1056	cytidyltransferase-related domain
NIY04_04860	COG1051	belongs to the nudix hydrolase family
NIY04_04870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NIY04_04885	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NIY04_04900	COG4625	pathogenesis
NIY04_04905	COG0583	DNA-binding transcription factor activity
NIY04_04910	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NIY04_04915	COG4208	sulfate ABC transporter
NIY04_04920	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NIY04_04930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NIY04_04935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NIY04_04940	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIY04_04960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIY04_04970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NIY04_04980	COG0681	Belongs to the peptidase S26 family
NIY04_04995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIY04_05005	COG1381	Involved in DNA repair and RecF pathway recombination
NIY04_05010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NIY04_05020	COG4221	oxidoreductase activity
NIY04_05050	COG0443	Heat shock 70 kDa protein
NIY04_05060	COG0436	Aminotransferase
NIY04_05080	COG0556	nucleotide-excision repair
NIY04_05135	COG2070	2-Nitropropane dioxygenase
NIY04_05165	COG1215	transferase activity, transferring glycosyl groups
NIY04_05180	COG0415	Belongs to the DNA photolyase family
NIY04_05190	COG1252	NADH dehydrogenase
NIY04_05195	COG1686	Belongs to the peptidase S11 family
NIY04_05210	COG1187	pseudouridine synthase activity
NIY04_05235	COG0477	Major facilitator Superfamily
NIY04_05240	COG0583	DNA-binding transcription factor activity
NIY04_05245	COG1823	symporter activity
NIY04_05255	COG0612	Peptidase, M16
NIY04_05280	COG0352	thiamine-phosphate diphosphorylase activity
NIY04_05315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY04_05325	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY04_05340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIY04_05345	COG0076	glutamate decarboxylase activity
NIY04_05355	COG1522	sequence-specific DNA binding
NIY04_05360	COG3961	Belongs to the TPP enzyme family
NIY04_05365	COG1113	amino acid transport
NIY04_05370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NIY04_05375	COG0573	inorganic phosphate transmembrane transporter activity
NIY04_05385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NIY04_05390	COG0616	signal peptide processing
NIY04_05425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NIY04_05430	COG1686	Belongs to the peptidase S11 family
NIY04_05455	COG0583	DNA-binding transcription factor activity
NIY04_05460	COG1067	ATP-dependent peptidase activity
NIY04_05485	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NIY04_05505	COG1966	Carbon starvation protein
NIY04_05510	COG2879	small protein
NIY04_05565	COG1335	isochorismatase
NIY04_05570	COG0583	DNA-binding transcription factor activity
NIY04_05585	COG0596	Alpha beta hydrolase
NIY04_05595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NIY04_05640	COG1741	Belongs to the pirin family
NIY04_05650	COG2964	Protein conserved in bacteria
NIY04_05665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY04_05670	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIY04_05675	COG4605	iron ion homeostasis
NIY04_05680	COG4604	ABC transporter, ATP-binding protein
NIY04_05685	COG4607	ABC-type enterochelin transport system periplasmic component
NIY04_05690	COG4774	siderophore transport
NIY04_05700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY04_05705	COG1021	2,3-dihydroxybenzoate-AMP ligase
NIY04_05710	COG1535	isochorismatase
NIY04_05710	COG3433	isochorismatase activity
NIY04_05720	COG1132	(ABC) transporter
NIY04_05725	COG1132	(ABC) transporter
NIY04_05730	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NIY04_05755	COG3739	integral membrane protein
NIY04_05775	COG0302	gtp cyclohydrolase
NIY04_05785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NIY04_05815	COG0308	aminopeptidase N
NIY04_05820	COG0512	Glutamine amidotransferase of anthranilate synthase
NIY04_05835	COG0174	glutamine synthetase
NIY04_05845	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NIY04_05880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NIY04_05885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIY04_05890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIY04_05910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NIY04_05915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NIY04_05920	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NIY04_05935	COG1960	acyl-CoA dehydrogenase activity
NIY04_05940	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NIY04_05945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY04_05955	COG2223	nitrite transmembrane transporter activity
NIY04_05965	COG0024	Methionine aminopeptidase
NIY04_05970	COG0052	Belongs to the universal ribosomal protein uS2 family
NIY04_05985	COG2207	Transcriptional regulator
NIY04_06010	COG2951	lytic endotransglycosylase activity
NIY04_06015	COG0772	Belongs to the SEDS family
NIY04_06030	COG0842	Transport permease protein
NIY04_06035	COG1131	(ABC) transporter
NIY04_06080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY04_06095	COG4215	(ABC) transporter
NIY04_06100	COG4160	amino acid transport
NIY04_06105	COG4598	ABC transporter
NIY04_06115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NIY04_06120	COG0826	peptidase U32
NIY04_06125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY04_06140	COG1720	tRNA m6t6A37 methyltransferase activity
NIY04_06150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NIY04_06165	COG0642	Histidine kinase
NIY04_06175	COG0494	nUDIX hydrolase
NIY04_06185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NIY04_06190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIY04_06195	COG3139	Protein of unknown function (DUF1315)
NIY04_06200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIY04_06205	COG1301	dicarboxylic acid transport
NIY04_06210	COG1960	acyl-CoA dehydrogenase activity
NIY04_06215	COG2819	hydrolase of the alpha beta superfamily
NIY04_06225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NIY04_06235	COG2195	Cleaves the N-terminal amino acid of tripeptides
NIY04_06255	COG1690	Belongs to the RtcB family
NIY04_06260	COG1234	tRNA 3'-trailer cleavage
NIY04_06265	COG4650	regulator
NIY04_06295	COG2363	Small membrane protein
NIY04_06320	COG0513	Belongs to the DEAD box helicase family
NIY04_06330	COG0778	Nitroreductase
NIY04_06360	COG1286	toxin biosynthetic process
NIY04_06385	COG4783	chaperone-mediated protein folding
NIY04_06390	COG1610	YqeY-like protein
NIY04_06420	COG0515	serine threonine protein kinase
NIY04_06420	COG2815	serine threonine protein kinase
NIY04_06490	COG3111	PFAM Bacterial OB fold (BOF) protein
NIY04_06515	COG3243	poly(R)-hydroxyalkanoic acid synthase
NIY04_06520	COG0786	glutamate:sodium symporter activity
NIY04_06530	COG2186	Transcriptional regulator
NIY04_06580	COG0477	Major facilitator Superfamily
NIY04_06585	COG1051	belongs to the nudix hydrolase family
NIY04_06615	COG2995	paraquat-inducible protein a
NIY04_06620	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NIY04_06620	COG3008	intermembrane lipid transfer
NIY04_06635	COG1794	racemase activity, acting on amino acids and derivatives
NIY04_06665	COG1301	dicarboxylic acid transport
NIY04_06675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY04_06680	COG2011	ABC-type metal ion transport system permease component
NIY04_06685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIY04_06690	COG1464	Belongs to the NlpA lipoprotein family
NIY04_06695	COG0151	Belongs to the GarS family
NIY04_06700	COG0138	bifunctional purine biosynthesis protein purh
NIY04_06705	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NIY04_06735	COG2308	Evidence 4 Homologs of previously reported genes of
NIY04_06745	COG1305	Transglutaminase-like
NIY04_06755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIY04_06760	COG0305	Participates in initiation and elongation during chromosome replication
NIY04_06785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NIY04_06795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NIY04_06800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NIY04_06825	COG0726	polysaccharide deacetylase
NIY04_06825	COG1649	PFAM Uncharacterised BCR, COG1649
NIY04_06830	COG1215	transferase activity, transferring glycosyl groups
NIY04_06835	COG3658	cytochrome
NIY04_06845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIY04_06860	COG0583	DNA-binding transcription factor activity
NIY04_06890	COG1960	acyl-CoA dehydrogenase activity
NIY04_06895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY04_06900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY04_06915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NIY04_06925	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NIY04_06930	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NIY04_06935	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NIY04_06940	COG2205	protein histidine kinase activity
NIY04_06945	COG0745	RESPONSE REGULATOR receiver
NIY04_06950	COG0174	glutamine synthetase
NIY04_06970	COG0729	surface antigen
NIY04_06995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NIY04_07000	COG2814	Major facilitator Superfamily
NIY04_07015	COG0583	DNA-binding transcription factor activity
NIY04_07030	COG1187	pseudouridine synthase activity
NIY04_07050	COG0802	atpase or kinase
NIY04_07055	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIY04_07065	COG1923	regulation of RNA biosynthetic process
NIY04_07070	COG0697	spore germination
NIY04_07095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIY04_07100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NIY04_07100	COG0519	Catalyzes the synthesis of GMP from XMP
NIY04_07105	COG4302	ethanolamine ammonia-lyase activity
NIY04_07110	COG4303	Ethanolamine ammonia lyase large subunit
NIY04_07115	COG0531	amino acid
NIY04_07135	COG1454	alcohol dehydrogenase
NIY04_07140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NIY04_07165	COG0308	aminopeptidase N
NIY04_07205	COG1605	Chorismate mutase
NIY04_07225	COG1309	transcriptional regulator
NIY04_07235	COG0668	transmembrane transport
NIY04_07265	COG4773	Receptor
NIY04_07285	COG0488	(ABC) transporter
NIY04_07290	COG0589	response to stress
NIY04_07310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NIY04_07320	COG3135	benzoate transporter
NIY04_07325	COG1522	sequence-specific DNA binding
NIY04_07335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NIY04_07340	COG0583	DNA-binding transcription factor activity
NIY04_07350	COG0183	Belongs to the thiolase family
NIY04_07360	COG2030	dehydratase
NIY04_07365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NIY04_07380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIY04_07390	COG0824	Thioesterase
NIY04_07395	COG1454	alcohol dehydrogenase
NIY04_07405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIY04_07425	COG0069	glutamate synthase activity
NIY04_07570	COG3617	BRO family, N-terminal domain
NIY04_07610	COG5410	chromosome segregation
NIY04_07715	COG1598	PFAM Uncharacterised protein family UPF0150
NIY04_07785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIY04_07800	COG2814	Major facilitator Superfamily
NIY04_07815	COG0511	ligase activity, forming carbon-carbon bonds
NIY04_07835	COG1116	anion transmembrane transporter activity
NIY04_07835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY04_07840	COG0745	RESPONSE REGULATOR receiver
NIY04_07850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY04_07850	COG2146	nitrite reductase [NAD(P)H] activity
NIY04_07855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY04_07860	COG0243	molybdopterin cofactor binding
NIY04_07870	COG0243	molybdopterin cofactor binding
NIY04_07875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NIY04_07890	COG0315	cyclic pyranopterin monophosphate synthase activity
NIY04_07890	COG0521	Mo-molybdopterin cofactor biosynthetic process
NIY04_07895	COG0303	'Molybdopterin
NIY04_07905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY04_07910	COG0697	spore germination
NIY04_07930	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NIY04_07935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIY04_07990	COG2204	response regulator
NIY04_07995	COG3852	Histidine kinase
NIY04_08020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIY04_08025	COG0575	Belongs to the CDS family
NIY04_08040	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NIY04_08060	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NIY04_08075	COG2137	regulation of response to DNA damage stimulus
NIY04_08085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NIY04_08090	COG1011	Hydrolase
NIY04_08115	COG1522	sequence-specific DNA binding
NIY04_08125	COG1113	amino acid transport
NIY04_08145	COG0659	secondary active sulfate transmembrane transporter activity
NIY04_08150	COG2135	peptidase activity
NIY04_08165	COG5001	Diguanylate cyclase
NIY04_08165	COG3300	MHYT domain
NIY04_08180	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NIY04_08180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NIY04_08180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NIY04_08185	COG1105	Belongs to the carbohydrate kinase PfkB family
NIY04_08190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIY04_08190	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIY04_08220	COG0024	Methionine aminopeptidase
NIY04_08225	COG0583	DNA-binding transcription factor activity
NIY04_08235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NIY04_08240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NIY04_08245	COG0517	IMP dehydrogenase activity
NIY04_08245	COG0516	GMP reductase activity
NIY04_08270	COG0552	protein localization to endoplasmic reticulum
NIY04_08280	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NIY04_08295	COG4890	Cyd operon protein YbgT
NIY04_08300	COG1294	oxidase, subunit
NIY04_08315	COG1585	Membrane protein implicated in regulation of membrane protease activity
NIY04_08325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIY04_08330	COG4774	siderophore transport
NIY04_08345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NIY04_08350	COG0569	domain protein
NIY04_08355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIY04_08385	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NIY04_08390	COG0542	response to heat
NIY04_08415	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY04_08415	COG1902	pentaerythritol trinitrate reductase activity
NIY04_08460	COG2323	membrane
NIY04_08465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NIY04_08475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIY04_08480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY04_08485	COG0183	Belongs to the thiolase family
NIY04_08490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIY04_08495	COG0596	Alpha beta hydrolase
NIY04_08500	COG2271	Major facilitator Superfamily
NIY04_08505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIY04_08510	COG3485	protocatechuate 3,4-dioxygenase
NIY04_08515	COG3485	protocatechuate 3,4-dioxygenase
NIY04_08520	COG0710	3-dehydroquinate dehydratase activity
NIY04_08525	COG3420	alginic acid biosynthetic process
NIY04_08530	COG3659	wide pore channel activity
NIY04_08535	COG4993	Dehydrogenase
NIY04_08545	COG2391	methyltransferase activity
NIY04_08560	COG1414	Transcriptional regulator
NIY04_08565	COG0583	DNA-binding transcription factor activity
NIY04_08570	COG1960	acyl-CoA dehydrogenase activity
NIY04_08595	COG2814	Major facilitator Superfamily
NIY04_08605	COG0154	amidase activity
NIY04_08625	COG4638	Rieske (2fe-2S)
NIY04_08635	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_08645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY04_08655	COG3733	amine oxidase
NIY04_08665	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_08675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY04_08680	COG0183	Belongs to the thiolase family
NIY04_08685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY04_08690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIY04_08700	COG4829	muconolactone delta-isomerase
NIY04_08705	COG4948	Mandelate Racemase Muconate Lactonizing
NIY04_08710	COG0583	DNA-binding transcription factor activity
NIY04_08720	COG2186	Transcriptional regulator
NIY04_08740	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_08755	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY04_08755	COG1902	pentaerythritol trinitrate reductase activity
NIY04_08765	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIY04_08775	COG0789	Transcriptional regulator
NIY04_08800	COG1309	transcriptional regulator
NIY04_08805	COG0583	DNA-binding transcription factor activity
NIY04_08810	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_08815	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_08820	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_08830	COG1960	acyl-CoA dehydrogenase activity
NIY04_08840	COG0318	PFAM AMP-dependent synthetase and ligase
NIY04_08915	COG2188	Transcriptional regulator
NIY04_08930	COG0583	DNA-binding transcription factor activity
NIY04_08945	COG1566	PFAM secretion protein HlyD family protein
NIY04_08960	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_08965	COG0129	dihydroxy-acid dehydratase activity
NIY04_08975	COG0583	DNA-binding transcription factor activity
NIY04_08980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NIY04_08990	COG2084	Dehydrogenase
NIY04_08995	COG2207	Transcriptional regulator
NIY04_09000	COG1064	alcohol dehydrogenase
NIY04_09010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIY04_09015	COG1120	ATPase activity
NIY04_09110	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NIY04_09145	COG2856	Zn peptidase
NIY04_09200	COG2207	Transcriptional regulator
NIY04_09215	COG2205	protein histidine kinase activity
NIY04_09220	COG0745	RESPONSE REGULATOR receiver
NIY04_09225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY04_09230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIY04_09310	COG3539	Fimbrial protein
NIY04_09335	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NIY04_09345	COG0753	catalase activity
NIY04_09360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIY04_09420	COG1535	isochorismatase
NIY04_09420	COG3433	isochorismatase activity
NIY04_09425	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_09430	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NIY04_09435	COG4149	molybdate abc transporter
NIY04_09440	COG0725	ABC transporter, periplasmic molybdate-binding protein
NIY04_09450	COG4638	Rieske (2fe-2S)
NIY04_09455	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NIY04_09460	COG0543	2 iron, 2 sulfur cluster binding
NIY04_09460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY04_09475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY04_09485	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_09500	COG2207	Transcriptional regulator
NIY04_09505	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_09510	COG2610	gluconate transmembrane transporter activity
NIY04_09520	COG1309	transcriptional regulator
NIY04_09545	COG0583	DNA-binding transcription factor activity
NIY04_09560	COG2031	fatty acid transporter
NIY04_09565	COG0183	Belongs to the thiolase family
NIY04_09570	COG0583	DNA-binding transcription factor activity
NIY04_09575	COG0583	DNA-binding transcription factor activity
NIY04_09590	COG1027	Aspartate ammonia-lyase
NIY04_09600	COG0477	Major facilitator Superfamily
NIY04_09620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY04_09625	COG4521	taurine ABC transporter
NIY04_09640	COG2188	Transcriptional regulator
NIY04_09650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NIY04_09655	COG1733	regulation of RNA biosynthetic process
NIY04_09660	COG2207	Transcriptional regulator
NIY04_09660	COG3708	Transcriptional regulator
NIY04_09675	COG0730	response to heat
NIY04_09690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY04_09690	COG3453	Protein conserved in bacteria
NIY04_09700	COG3781	membrane
NIY04_09705	COG1063	alcohol dehydrogenase
NIY04_09715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY04_09720	COG0508	dehydrogenase complex catalyzes the overall conversion of
NIY04_09725	COG0022	dehydrogenase e1 component
NIY04_09730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NIY04_09735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NIY04_09750	COG3706	GGDEF domain
NIY04_09765	COG0133	tryptophan synthase activity
NIY04_09775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIY04_09805	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NIY04_09810	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIY04_09835	COG2226	methyltransferase
NIY04_09890	COG0842	Transport permease protein
NIY04_09895	COG0842	Transport permease protein
NIY04_09900	COG1131	(ABC) transporter
NIY04_09915	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NIY04_09920	COG4773	Receptor
NIY04_09940	COG0730	response to heat
NIY04_09945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NIY04_09960	COG0406	alpha-ribazole phosphatase activity
NIY04_09965	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NIY04_09980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NIY04_10010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NIY04_10020	COG4264	IucA IucC family
NIY04_10025	COG4264	IucA IucC family
NIY04_10030	COG2814	Major facilitator Superfamily
NIY04_10045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIY04_10060	COG1960	acyl-CoA dehydrogenase activity
NIY04_10065	COG1960	acyl-CoA dehydrogenase activity
NIY04_10070	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIY04_10075	COG2207	Transcriptional regulator
NIY04_10080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NIY04_10085	COG0776	regulation of translation
NIY04_10110	COG0822	iron-sulfur transferase activity
NIY04_10115	COG0316	Belongs to the HesB IscA family
NIY04_10145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIY04_10165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NIY04_10170	COG0702	epimerase
NIY04_10205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIY04_10215	COG0339	signal peptide processing
NIY04_10265	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NIY04_10385	COG4695	Portal protein
NIY04_10550	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NIY04_10580	COG0776	regulation of translation
NIY04_10645	COG0084	hydrolase, TatD family'
NIY04_10665	COG1663	tetraacyldisaccharide 4'-kinase activity
NIY04_10670	COG1132	(ABC) transporter
NIY04_10680	COG0811	peptide transport
NIY04_10685	COG1475	DNA binding
NIY04_10690	COG1192	Involved in chromosome partitioning
NIY04_10700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NIY04_10715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NIY04_10720	COG0191	fructose-bisphosphate aldolase activity
NIY04_10740	COG0424	maF-like protein
NIY04_10745	COG2850	peptidyl-arginine hydroxylation
NIY04_10755	COG0640	Transcriptional regulator
NIY04_10765	COG3619	membrane
NIY04_10770	COG3122	Protein conserved in bacteria
NIY04_10775	COG1132	(ABC) transporter
NIY04_10795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NIY04_10800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIY04_10810	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NIY04_10810	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NIY04_10810	COG0506	proline dehydrogenase activity
NIY04_10815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIY04_10830	COG3698	Phosphodiester glycosidase
NIY04_10840	COG2353	YceI-like domain
NIY04_10850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIY04_10895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIY04_10895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NIY04_10920	COG3539	Fimbrial protein
NIY04_10925	COG3121	Chaperone
NIY04_10950	COG0697	spore germination
NIY04_10960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NIY04_10970	COG0583	DNA-binding transcription factor activity
NIY04_10990	COG1309	transcriptional regulator
NIY04_11005	COG1522	sequence-specific DNA binding
NIY04_11015	COG1126	abc transporter atp-binding protein
NIY04_11020	COG0765	amino acid transport
NIY04_11025	COG0765	amino acid transport
NIY04_11055	COG1464	Belongs to the NlpA lipoprotein family
NIY04_11065	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIY04_11070	COG2011	ABC-type metal ion transport system permease component
NIY04_11075	COG0012	GTP binding
NIY04_11100	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NIY04_11140	COG0386	Belongs to the glutathione peroxidase family
NIY04_11150	COG0436	Aminotransferase
NIY04_11155	COG1301	dicarboxylic acid transport
NIY04_11190	COG3634	alkyl hydroperoxide reductase activity
NIY04_11205	COG0583	DNA-binding transcription factor activity
NIY04_11210	COG0798	PFAM Bile acid sodium symporter
NIY04_11215	COG0640	Transcriptional regulator
NIY04_11230	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NIY04_11240	COG0583	DNA-binding transcription factor activity
NIY04_11250	COG1953	Uracil, thiamine, allantoin
NIY04_11260	COG2175	clavaminate synthase activity
NIY04_11265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY04_11270	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NIY04_11275	COG4521	taurine ABC transporter
NIY04_11285	COG0477	Major facilitator Superfamily
NIY04_11305	COG1271	oxidase subunit
NIY04_11310	COG1294	oxidase, subunit
NIY04_11320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY04_11340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NIY04_11360	COG3052	prosthetic group binding
NIY04_11365	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NIY04_11375	COG0583	DNA-binding transcription factor activity
NIY04_11385	COG2814	Major facilitator Superfamily
NIY04_11400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY04_11405	COG1346	cytolysis
NIY04_11415	COG0583	DNA-binding transcription factor activity
NIY04_11420	COG0625	glutathione transferase activity
NIY04_11425	COG0625	glutathione transferase activity
NIY04_11430	COG0583	DNA-binding transcription factor activity
NIY04_11445	COG1045	serine acetyltransferase
NIY04_11450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NIY04_11455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIY04_11480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY04_11485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY04_11495	COG0765	amino acid transport
NIY04_11500	COG0765	amino acid transport
NIY04_11520	COG0784	Response regulator, receiver
NIY04_11520	COG2205	protein histidine kinase activity
NIY04_11560	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_11610	COG0583	DNA-binding transcription factor activity
NIY04_11630	COG0318	PFAM AMP-dependent synthetase and ligase
NIY04_11635	COG1309	transcriptional regulator
NIY04_11640	COG1960	acyl-CoA dehydrogenase activity
NIY04_11645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NIY04_11650	COG1024	Enoyl-CoA hydratase
NIY04_11655	COG4770	biotin carboxylase activity
NIY04_11665	COG0583	DNA-binding transcription factor activity
NIY04_11685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NIY04_11690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NIY04_11705	COG3842	ATPase activity
NIY04_11710	COG1840	ABC-type Fe3 transport system, periplasmic component
NIY04_11725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY04_11730	COG1414	Transcriptional regulator
NIY04_11740	COG0583	DNA-binding transcription factor activity
NIY04_11745	COG3038	cytochrome b561
NIY04_11750	COG0753	catalase activity
NIY04_11785	COG2050	protein possibly involved in aromatic compounds catabolism
NIY04_11795	COG3327	negative regulation of DNA-templated transcription, initiation
NIY04_11800	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NIY04_11805	COG0183	Belongs to the thiolase family
NIY04_11810	COG1250	3-hydroxyacyl-CoA dehydrogenase
NIY04_11815	COG1024	Enoyl-CoA hydratase
NIY04_11820	COG1024	Enoyl-CoA hydratase
NIY04_11825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY04_11830	COG2151	metal-sulfur cluster biosynthetic enzyme
NIY04_11835	COG3396	Phenylacetate-CoA oxygenase
NIY04_11840	COG3460	Phenylacetate-CoA oxygenase
NIY04_11845	COG3396	Phenylacetate-CoA oxygenase
NIY04_11850	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_11850	COG2030	dehydratase
NIY04_11855	COG1760	l-serine dehydratase
NIY04_11860	COG0531	amino acid
NIY04_11865	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_11890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NIY04_11910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY04_11920	COG0789	Transcriptional regulator
NIY04_11930	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NIY04_11945	COG2807	transmembrane transport
NIY04_11950	COG0590	tRNA wobble adenosine to inosine editing
NIY04_12060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NIY04_12085	COG1116	anion transmembrane transporter activity
NIY04_12090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY04_12100	COG0864	Transcriptional regulator
NIY04_12120	COG1733	regulation of RNA biosynthetic process
NIY04_12125	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY04_12130	COG0439	Biotin carboxylase
NIY04_12145	COG1063	alcohol dehydrogenase
NIY04_12155	COG1309	transcriptional regulator
NIY04_12165	COG0038	chloride channel
NIY04_12170	COG4770	biotin carboxylase activity
NIY04_12190	COG1914	H( )-stimulated, divalent metal cation uptake system
NIY04_12195	COG0583	DNA-binding transcription factor activity
NIY04_12230	COG1250	3-hydroxyacyl-CoA dehydrogenase
NIY04_12250	COG2814	Major facilitator Superfamily
NIY04_12270	COG0598	Magnesium transport protein CorA
NIY04_12275	COG1560	Kdo2-lipid A biosynthetic process
NIY04_12290	COG1522	sequence-specific DNA binding
NIY04_12305	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NIY04_12315	COG4122	O-methyltransferase activity
NIY04_12345	COG1538	Outer membrane efflux protein
NIY04_12350	COG1137	ATPase activity
NIY04_12355	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NIY04_12365	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NIY04_12370	COG0517	IMP dehydrogenase activity
NIY04_12370	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NIY04_12405	COG2814	Major facilitator Superfamily
NIY04_12440	COG1278	Cold shock
NIY04_12445	COG1280	lysine exporter protein (LysE YggA)
NIY04_12475	COG1570	exodeoxyribonuclease VII activity
NIY04_12525	COG0583	DNA-binding transcription factor activity
NIY04_12530	COG4638	Rieske (2fe-2S)
NIY04_12535	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NIY04_12540	COG0543	2 iron, 2 sulfur cluster binding
NIY04_12540	COG0633	Ferredoxin
NIY04_12545	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_12550	COG3135	benzoate transporter
NIY04_12555	COG2814	Major facilitator Superfamily
NIY04_12570	COG1643	Atp-dependent helicase
NIY04_12575	COG0450	alkyl hydroperoxide reductase
NIY04_12585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NIY04_12595	COG3634	alkyl hydroperoxide reductase activity
NIY04_12615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NIY04_12620	COG0625	glutathione transferase activity
NIY04_12630	COG2885	chlorophyll binding
NIY04_12665	COG0542	response to heat
NIY04_12680	COG1765	OsmC-like protein
NIY04_12695	COG0667	Aldo Keto reductase
NIY04_12710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIY04_12730	COG0582	viral genome integration into host DNA
NIY04_12865	COG3566	protein conserved in bacteria
NIY04_12885	COG3567	Phage-associated protein, HI1409 family
NIY04_12890	COG5410	chromosome segregation
NIY04_12970	COG4197	protein conserved in bacteria, prophage-related
NIY04_12975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIY04_13025	COG0527	aspartate kinase activity
NIY04_13035	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIY04_13045	COG3038	cytochrome b561
NIY04_13050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NIY04_13055	COG2252	PERMEase
NIY04_13065	COG2072	flavoprotein involved in K transport
NIY04_13080	COG1741	Belongs to the pirin family
NIY04_13085	COG1309	transcriptional regulator
NIY04_13095	COG0300	oxidoreductase activity
NIY04_13100	COG2072	flavoprotein involved in K transport
NIY04_13105	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NIY04_13150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY04_13165	COG2814	Major facilitator Superfamily
NIY04_13170	COG1024	Enoyl-CoA hydratase
NIY04_13175	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_13185	COG1960	acyl-CoA dehydrogenase activity
NIY04_13210	COG2186	Transcriptional regulator
NIY04_13215	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_13225	COG4948	Mandelate Racemase Muconate Lactonizing
NIY04_13230	COG2271	Major facilitator Superfamily
NIY04_13235	COG2721	sulfolactate sulfo-lyase activity
NIY04_13240	COG0697	spore germination
NIY04_13270	COG1113	amino acid transport
NIY04_13290	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_13310	COG0531	amino acid
NIY04_13320	COG1113	amino acid transport
NIY04_13365	COG0583	DNA-binding transcription factor activity
NIY04_13375	COG0251	oxidation-reduction process
NIY04_13420	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY04_13420	COG1902	pentaerythritol trinitrate reductase activity
NIY04_13435	COG2203	Gaf domain
NIY04_13435	COG3706	GGDEF domain
NIY04_13435	COG4251	negative regulation of phosphorylation
NIY04_13435	COG5001	Diguanylate cyclase
NIY04_13445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIY04_13465	COG4172	Belongs to the ABC transporter superfamily
NIY04_13470	COG4239	(ABC) transporter, permease
NIY04_13475	COG4174	ABC transporter (Permease)
NIY04_13485	COG0741	lytic transglycosylase activity
NIY04_13485	COG1388	LysM domain
NIY04_13485	COG1388	LysM domain
NIY04_13485	COG0741	lytic transglycosylase activity
NIY04_13490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIY04_13530	COG0583	DNA-binding transcription factor activity
NIY04_13535	COG1279	arginine transmembrane transporter activity
NIY04_13555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY04_13560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY04_13565	COG0006	proline dipeptidase activity
NIY04_13605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIY04_13630	COG3384	dioxygenase
NIY04_13640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NIY04_13645	COG2878	Part of a membrane complex involved in electron transport
NIY04_13650	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIY04_13675	COG0768	penicillin binding
NIY04_13680	COG0742	ribosomal rna small subunit methyltransferase
NIY04_13695	COG0830	nickel cation binding
NIY04_13705	COG0804	urea catabolic process
NIY04_13750	COG1253	flavin adenine dinucleotide binding
NIY04_13755	COG2851	Citrate transporter
NIY04_13805	COG1773	rubredoxin
NIY04_13810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY04_13820	COG0583	DNA-binding transcription factor activity
NIY04_13850	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NIY04_13855	COG4181	ATPase activity
NIY04_13900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NIY04_13920	COG0306	phosphate transporter
NIY04_13935	COG3958	Transketolase
NIY04_13940	COG3959	Transketolase, thiamine diphosphate binding domain
NIY04_13945	COG2271	Major facilitator Superfamily
NIY04_13950	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_13955	COG0583	DNA-binding transcription factor activity
NIY04_13975	COG2223	nitrite transmembrane transporter activity
NIY04_13980	COG2207	Transcriptional regulator
NIY04_13985	COG2066	Belongs to the glutaminase family
NIY04_13990	COG0242	peptide deformylase activity
NIY04_13995	COG0477	Major facilitator Superfamily
NIY04_14005	COG0028	Belongs to the TPP enzyme family
NIY04_14020	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_14025	COG2267	carboxylic ester hydrolase activity
NIY04_14035	COG2271	Major facilitator Superfamily
NIY04_14040	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY04_14050	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_14070	COG1414	Transcriptional regulator
NIY04_14085	COG1024	Enoyl-CoA hydratase
NIY04_14095	COG1215	transferase activity, transferring glycosyl groups
NIY04_14100	COG1649	PFAM Uncharacterised BCR, COG1649
NIY04_14100	COG0726	polysaccharide deacetylase
NIY04_14110	COG4681	YaeQ
NIY04_14120	COG0523	cobalamin synthesis protein
NIY04_14130	COG1607	acyl-coa hydrolase
NIY04_14140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY04_14145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY04_14150	COG1309	transcriptional regulator
NIY04_14175	COG2040	homocysteine
NIY04_14180	COG0531	amino acid
NIY04_14205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY04_14210	COG0477	Major facilitator Superfamily
NIY04_14250	COG0405	Gamma-glutamyltransferase
NIY04_14255	COG2814	Major facilitator Superfamily
NIY04_14265	COG2050	protein possibly involved in aromatic compounds catabolism
NIY04_14280	COG1090	epimerase
NIY04_14300	COG0420	3'-5' exonuclease activity
NIY04_14325	COG0735	belongs to the Fur family
NIY04_14330	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NIY04_14350	COG0121	glutamine amidotransferase
NIY04_14365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIY04_14375	COG0210	DNA helicase
NIY04_14380	COG2885	chlorophyll binding
NIY04_14385	COG0204	Acyl-transferase
NIY04_14400	COG2894	cell division
NIY04_14415	COG1280	lysine exporter protein (LysE YggA)
NIY04_14420	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NIY04_14420	COG1674	ftsk spoiiie
NIY04_14425	COG0492	ferredoxin-NADP+ reductase activity
NIY04_14430	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NIY04_14440	COG0456	acetyltransferase
NIY04_14485	COG1981	membrane
NIY04_14500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIY04_14500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NIY04_14520	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_14530	COG0657	acetylesterase activity
NIY04_14540	COG0473	3-isopropylmalate dehydrogenase activity
NIY04_14545	COG0583	DNA-binding transcription factor activity
NIY04_14565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NIY04_14590	COG0564	pseudouridine synthase activity
NIY04_14600	COG0358	DNA primase activity
NIY04_14615	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NIY04_14645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIY04_14675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NIY04_14685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIY04_14685	COG0352	thiamine-phosphate diphosphorylase activity
NIY04_14685	COG0351	phosphomethylpyrimidine kinase
NIY04_14690	COG1652	LysM domain
NIY04_14715	COG1399	metal-binding, possibly nucleic acid-binding protein
NIY04_14720	COG3101	peptidyl-lysine hydroxylation
NIY04_14725	COG0009	L-threonylcarbamoyladenylate synthase
NIY04_14730	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIY04_14735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIY04_14750	COG4106	trans-aconitate 2-methyltransferase activity
NIY04_14765	COG0596	Alpha beta hydrolase
NIY04_14765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY04_14765	COG2226	methyltransferase
NIY04_14770	COG1877	trehalose-phosphatase activity
NIY04_14775	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NIY04_14780	COG2223	nitrite transmembrane transporter activity
NIY04_14800	COG1196	nuclear chromosome segregation
NIY04_14810	COG0730	response to heat
NIY04_14825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIY04_14835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIY04_14885	COG0489	protein tyrosine kinase activity
NIY04_14895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY04_14895	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY04_14925	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NIY04_14930	COG2081	HI0933 family
NIY04_14940	COG0668	transmembrane transport
NIY04_14960	COG0583	DNA-binding transcription factor activity
NIY04_14985	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NIY04_14990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NIY04_15020	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NIY04_15060	COG0745	RESPONSE REGULATOR receiver
NIY04_15080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIY04_15135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY04_15150	COG0583	DNA-binding transcription factor activity
NIY04_15180	COG0583	DNA-binding transcription factor activity
NIY04_15195	COG0583	DNA-binding transcription factor activity
NIY04_15200	COG1053	succinate dehydrogenase
NIY04_15210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NIY04_15215	COG2814	Major facilitator Superfamily
NIY04_15220	COG1960	acyl-CoA dehydrogenase activity
NIY04_15225	COG0583	DNA-binding transcription factor activity
NIY04_15230	COG1063	alcohol dehydrogenase
NIY04_15260	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NIY04_15265	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIY04_15270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIY04_15290	COG2132	Multicopper oxidase
NIY04_15300	COG0561	phosphatase activity
NIY04_15305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NIY04_15330	COG1214	PFAM Peptidase M22, glycoprotease
NIY04_15380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIY04_15390	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIY04_15395	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NIY04_15400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIY04_15460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIY04_15470	COG1846	Transcriptional regulator
NIY04_15475	COG1764	response to oxidative stress
NIY04_15515	COG0037	tRNA processing
NIY04_15525	COG0248	Ppx GppA phosphatase
NIY04_15555	COG0072	phenylalanine-tRNA ligase activity
NIY04_15600	COG1238	metal cluster binding
NIY04_15605	COG0625	glutathione transferase activity
NIY04_15620	COG0318	PFAM AMP-dependent synthetase and ligase
NIY04_15625	COG3028	Belongs to the UPF0307 family
NIY04_15630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIY04_15650	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NIY04_15655	COG0617	tRNA 3'-terminal CCA addition
NIY04_15660	COG1555	photosystem II stabilization
NIY04_15665	COG3956	TIGRFAM MazG family protein
NIY04_15675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIY04_15695	COG5002	protein histidine kinase activity
NIY04_15695	COG0784	Response regulator, receiver
NIY04_15695	COG2205	protein histidine kinase activity
NIY04_15700	COG1024	Enoyl-CoA hydratase
NIY04_15705	COG2084	Dehydrogenase
NIY04_15710	COG3622	Belongs to the hyi family
NIY04_15740	COG0697	spore germination
NIY04_15750	COG2814	Major facilitator Superfamily
NIY04_15755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIY04_15765	COG0583	DNA-binding transcription factor activity
NIY04_15775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NIY04_15785	COG0084	hydrolase, TatD family'
NIY04_15800	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NIY04_15850	COG0440	acetolactate synthase activity
NIY04_15855	COG0028	Belongs to the TPP enzyme family
NIY04_15880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY04_15885	COG0577	efflux transmembrane transporter activity
NIY04_15885	COG1136	(ABC) transporter
NIY04_15890	COG1538	Outer membrane efflux protein
NIY04_15905	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NIY04_15910	COG1162	GTPase activity
NIY04_15920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NIY04_15940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NIY04_15945	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_15985	COG2986	histidine ammonia-lyase
NIY04_15995	COG1216	Glycosyl transferase, family 2
NIY04_16000	COG0318	PFAM AMP-dependent synthetase and ligase
NIY04_16010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIY04_16055	COG1426	Protein conserved in bacteria
NIY04_16090	COG0793	Belongs to the peptidase S41A family
NIY04_16105	COG2267	carboxylic ester hydrolase activity
NIY04_16115	COG1012	belongs to the aldehyde dehydrogenase family
NIY04_16120	COG3265	gluconokinase activity
NIY04_16130	COG0800	Aldolase
NIY04_16140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIY04_16145	COG0280	phosphate acetyltransferase
NIY04_16145	COG0857	belongs to the CobB CobQ family
NIY04_16150	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NIY04_16150	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NIY04_16170	COG0740	serine-type endopeptidase activity
NIY04_16180	COG4774	siderophore transport
NIY04_16190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NIY04_16200	COG2813	Specifically methylates the guanine in position
NIY04_16200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY04_16300	COG0788	formyltetrahydrofolate deformylase activity
NIY04_16325	COG4651	solute:proton antiporter activity
NIY04_16325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NIY04_16345	COG0724	RNA recognition motif
NIY04_16350	COG0210	DNA helicase
NIY04_16375	COG1733	regulation of RNA biosynthetic process
NIY04_16385	COG2900	Belongs to the SlyX family
NIY04_16390	COG0488	(ABC) transporter
NIY04_16395	COG1280	lysine exporter protein (LysE YggA)
NIY04_16400	COG1560	Kdo2-lipid A biosynthetic process
NIY04_16410	COG1301	dicarboxylic acid transport
NIY04_16465	COG0473	3-isopropylmalate dehydrogenase activity
NIY04_16520	COG0583	DNA-binding transcription factor activity
NIY04_16530	COG0625	glutathione transferase activity
NIY04_16535	COG2378	regulation of single-species biofilm formation
NIY04_16540	COG0546	phosphoglycolate phosphatase activity
NIY04_16550	COG1530	ribonuclease E activity
NIY04_16555	COG0318	PFAM AMP-dependent synthetase and ligase
NIY04_16570	COG0583	DNA-binding transcription factor activity
NIY04_16575	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_16580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NIY04_16590	COG0534	Mate efflux family protein
NIY04_16605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NIY04_16630	COG0493	'glutamate synthase
NIY04_16630	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NIY04_16640	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NIY04_16645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY04_16660	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NIY04_16670	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
NIY04_16670	COG0644	oxidoreductase
NIY04_16680	COG0425	Belongs to the sulfur carrier protein TusA family
NIY04_16685	COG4535	Mg2 and Co2 transporter CorC
NIY04_16695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY04_16715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIY04_16720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NIY04_16720	COG0475	glutathione-regulated potassium exporter activity
NIY04_16735	COG0484	heat shock protein binding
NIY04_16740	COG0789	Transcriptional regulator
NIY04_16745	COG0598	Magnesium transport protein CorA
NIY04_16760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NIY04_16765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NIY04_16770	COG1074	ATP-dependent DNA helicase activity
NIY04_16775	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NIY04_16795	COG2226	methyltransferase
NIY04_16815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NIY04_16830	COG2111	Na H antiporter
NIY04_16830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NIY04_16835	COG1006	Multisubunit Na H antiporter MnhC subunit
NIY04_16840	COG0651	ATP synthesis coupled electron transport
NIY04_16845	COG1863	multisubunit Na H antiporter MnhE subunit
NIY04_16850	COG2212	antiporter activity
NIY04_16855	COG1320	monovalent cation:proton antiporter activity
NIY04_16870	COG0195	Participates in both transcription termination and antitermination
NIY04_16920	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NIY04_16925	COG0237	dephospho-CoA kinase activity
NIY04_16935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIY04_16950	COG0497	DNA recombination
NIY04_16960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIY04_16990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIY04_16990	COG2169	Transcriptional regulator
NIY04_16995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIY04_17060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NIY04_17075	COG0326	Molecular chaperone. Has ATPase activity
NIY04_17090	COG2056	Na+-H+ antiporter family
NIY04_17095	COG0596	Alpha beta hydrolase
NIY04_17190	COG0546	phosphoglycolate phosphatase activity
NIY04_17195	COG1716	ATPase activity
NIY04_17240	COG0181	hydroxymethylbilane synthase activity
NIY04_17250	COG3275	phosphorelay sensor kinase activity
NIY04_17270	COG1538	Outer membrane efflux protein
NIY04_17275	COG0697	spore germination
NIY04_17300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NIY04_17305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NIY04_17310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIY04_17315	COG0772	Belongs to the SEDS family
NIY04_17340	COG4974	Belongs to the 'phage' integrase family
NIY04_17345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY04_17355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NIY04_17365	COG2197	response regulator
NIY04_17380	COG0793	Belongs to the peptidase S41A family
NIY04_17385	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIY04_17390	COG0795	lipopolysaccharide-transporting ATPase activity
NIY04_17430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIY04_17430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIY04_17440	COG0004	ammonium transporteR
NIY04_17445	COG0347	Belongs to the P(II) protein family
NIY04_17465	COG0659	secondary active sulfate transmembrane transporter activity
NIY04_17470	COG0589	response to stress
NIY04_17535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY04_17555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NIY04_17570	COG0318	PFAM AMP-dependent synthetase and ligase
NIY04_17580	COG0477	Major facilitator Superfamily
NIY04_17585	COG2860	membrane
NIY04_17590	COG3012	SEC-C Motif Domain Protein
NIY04_17595	COG1253	flavin adenine dinucleotide binding
NIY04_17605	COG0477	Major facilitator Superfamily
NIY04_17615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIY04_17655	COG0655	NAD(P)H dehydrogenase (quinone) activity
NIY04_17665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NIY04_17735	COG0758	DNA mediated transformation
NIY04_17745	COG0697	spore germination
NIY04_17750	COG1309	transcriptional regulator
NIY04_17765	COG0386	Belongs to the glutathione peroxidase family
NIY04_17835	COG1121	(ABC) transporter
NIY04_17840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NIY04_17845	COG1280	lysine exporter protein (LysE YggA)
NIY04_17850	COG2837	iron assimilation
NIY04_17855	COG0281	malic enzyme
NIY04_17900	COG0519	Catalyzes the synthesis of GMP from XMP
NIY04_17900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NIY04_17905	COG4399	Belongs to the UPF0754 family
NIY04_17910	COG2259	Doxx family
NIY04_17915	COG0586	Pfam SNARE associated Golgi protein
NIY04_17930	COG1192	Involved in chromosome partitioning
NIY04_17940	COG0271	Belongs to the BolA IbaG family
NIY04_17980	COG3321	synthase
NIY04_17980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NIY04_17980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NIY04_17980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIY04_17985	COG1960	acyl-CoA dehydrogenase activity
NIY04_17990	COG0318	PFAM AMP-dependent synthetase and ligase
NIY04_17995	COG2197	response regulator
NIY04_18005	COG3916	Acyl-homoserine-lactone synthase
NIY04_18010	COG0477	Major facilitator Superfamily
NIY04_18015	COG1024	Enoyl-CoA hydratase
NIY04_18020	COG1024	Enoyl-CoA hydratase
NIY04_18025	COG1960	acyl-CoA dehydrogenase activity
NIY04_18030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY04_18050	COG1113	amino acid transport
NIY04_18055	COG1113	amino acid transport
NIY04_18060	COG0251	oxidation-reduction process
NIY04_18100	COG0564	pseudouridine synthase activity
NIY04_18180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NIY04_18195	COG1802	Transcriptional regulator
NIY04_18205	COG1448	Aminotransferase
NIY04_18210	COG0277	FAD linked oxidase domain protein
NIY04_18220	COG2186	Transcriptional regulator
NIY04_18230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIY04_18235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIY04_18250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NIY04_18255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NIY04_18280	COG0438	transferase activity, transferring glycosyl groups
NIY04_18310	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NIY04_18340	COG0728	peptidoglycan biosynthetic process
NIY04_18345	COG3023	N-Acetylmuramoyl-L-alanine amidase
NIY04_18405	COG0546	phosphoglycolate phosphatase activity
NIY04_18410	COG1028	Short-chain dehydrogenase reductase Sdr
NIY04_18430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY04_18435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY04_18440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIY04_18445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY04_18450	COG1116	anion transmembrane transporter activity
NIY04_18455	COG1309	transcriptional regulator
NIY04_18460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIY04_18470	COG0196	riboflavin kinase activity
NIY04_18475	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIY04_18485	COG1047	Peptidyl-prolyl cis-trans
NIY04_18525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIY04_18530	COG0657	acetylesterase activity
NIY04_18550	COG0583	DNA-binding transcription factor activity
NIY04_18580	COG2951	lytic endotransglycosylase activity
NIY04_18585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIY04_18600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NIY04_18610	COG0671	phosphoesterase, PA-phosphatase related
NIY04_18615	COG0861	Integral membrane protein TerC family
NIY04_18625	COG0754	glutathionylspermidine amidase activity
NIY04_18635	COG0402	S-adenosylhomocysteine deaminase activity
NIY04_18650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY04_18655	COG1230	cation diffusion facilitator family transporter
NIY04_18670	COG0706	membrane insertase activity