locus-tag	class	description
KZA74_00010	COG0592	DNA-directed DNA polymerase activity
KZA74_00020	COG0187	DNA topoisomerase II activity
KZA74_00030	COG0586	Pfam SNARE associated Golgi protein
KZA74_00035	COG0488	(ABC) transporter
KZA74_00060	COG0596	Alpha beta hydrolase
KZA74_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KZA74_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KZA74_00110	COG0733	neurotransmitter:sodium symporter activity
KZA74_00150	COG2233	PERMEase
KZA74_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZA74_00200	COG2814	Major facilitator Superfamily
KZA74_00205	COG0656	L-ascorbic acid biosynthetic process
KZA74_00210	COG0583	DNA-binding transcription factor activity
KZA74_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA74_00230	COG1064	alcohol dehydrogenase
KZA74_00235	COG2818	Glycosylase
KZA74_00250	COG1194	a g-specific adenine glycosylase
KZA74_00270	COG2983	Belongs to the UPF0260 family
KZA74_00275	COG2133	pyrroloquinoline quinone binding
KZA74_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KZA74_00285	COG2116	formate transmembrane transporter activity
KZA74_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KZA74_00310	COG1335	isochorismatase
KZA74_00315	COG0385	Bile acid
KZA74_00320	COG0534	Mate efflux family protein
KZA74_00325	COG1683	Conserved Protein
KZA74_00345	COG0625	glutathione transferase activity
KZA74_00355	COG1113	amino acid transport
KZA74_00365	COG0523	cobalamin synthesis protein
KZA74_00375	COG2188	Transcriptional regulator
KZA74_00405	COG0010	Belongs to the arginase family
KZA74_00425	COG1280	lysine exporter protein (LysE YggA)
KZA74_00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KZA74_00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KZA74_00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KZA74_00500	COG0753	catalase activity
KZA74_00550	COG0534	Mate efflux family protein
KZA74_00555	COG0436	Aminotransferase
KZA74_00560	COG2733	membrane
KZA74_00575	COG2918	glutathione biosynthetic process
KZA74_00590	COG1388	LysM domain
KZA74_00590	COG1705	Flagellar rod assembly protein muramidase FlgJ
KZA74_00625	COG3150	esterase
KZA74_00635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KZA74_00645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZA74_00655	COG2233	PERMEase
KZA74_00660	COG2351	hydroxyisourate hydrolase activity
KZA74_00695	COG3706	GGDEF domain
KZA74_00710	COG1393	Belongs to the ArsC family
KZA74_00715	COG0708	Exodeoxyribonuclease III
KZA74_00740	COG0189	ligase activity
KZA74_00760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KZA74_00770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KZA74_00785	COG4942	peptidase
KZA74_00795	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZA74_00805	COG2119	membrane
KZA74_00810	COG4774	siderophore transport
KZA74_00815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZA74_00815	COG0426	domain, Protein
KZA74_00840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KZA74_00860	COG1902	pentaerythritol trinitrate reductase activity
KZA74_00865	COG1519	Transferase
KZA74_00875	COG0668	transmembrane transport
KZA74_00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZA74_00890	COG1335	isochorismatase
KZA74_00895	COG1522	sequence-specific DNA binding
KZA74_00920	COG0784	Response regulator, receiver
KZA74_00920	COG2198	Histidine kinase
KZA74_00920	COG2205	protein histidine kinase activity
KZA74_00925	COG3162	membrane
KZA74_00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KZA74_00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KZA74_00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KZA74_00960	COG1309	transcriptional regulator
KZA74_00980	COG0352	thiamine-phosphate diphosphorylase activity
KZA74_00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KZA74_00980	COG0351	phosphomethylpyrimidine kinase
KZA74_00990	COG2814	Major facilitator Superfamily
KZA74_01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KZA74_01015	COG1113	amino acid transport
KZA74_01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KZA74_01030	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_01040	COG1335	isochorismatase
KZA74_01080	COG2814	Major facilitator Superfamily
KZA74_01085	COG0583	DNA-binding transcription factor activity
KZA74_01130	COG1733	regulation of RNA biosynthetic process
KZA74_01160	COG1733	regulation of RNA biosynthetic process
KZA74_01165	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZA74_01185	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KZA74_01190	COG2207	Transcriptional regulator
KZA74_01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KZA74_01260	COG2329	Antibiotic biosynthesis monooxygenase
KZA74_01290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KZA74_01320	COG0427	acetyl-CoA hydrolase
KZA74_01345	COG0659	secondary active sulfate transmembrane transporter activity
KZA74_01350	COG4221	oxidoreductase activity
KZA74_01375	COG0488	(ABC) transporter
KZA74_01440	COG0833	amino acid
KZA74_01485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KZA74_01490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KZA74_01505	COG2226	methyltransferase
KZA74_01555	COG0070	glutamate synthase
KZA74_01555	COG0067	glutamate synthase
KZA74_01555	COG0069	glutamate synthase activity
KZA74_01560	COG0493	'glutamate synthase
KZA74_01570	COG1704	LemA family
KZA74_01575	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KZA74_01585	COG4969	Belongs to the N-Me-Phe pilin family
KZA74_01590	COG3307	-O-antigen
KZA74_01610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KZA74_01625	COG0194	GDP metabolic process
KZA74_01675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KZA74_01695	COG5380	lipid catabolic process
KZA74_01700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KZA74_01725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KZA74_01730	COG0277	FAD linked oxidase domain protein
KZA74_01740	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KZA74_01745	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZA74_01760	COG1289	transmembrane transporter activity
KZA74_01770	COG0628	permease
KZA74_01775	COG1192	Involved in chromosome partitioning
KZA74_01805	COG0833	amino acid
KZA74_01810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KZA74_01815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KZA74_01825	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_01865	COG0583	DNA-binding transcription factor activity
KZA74_01915	COG0517	IMP dehydrogenase activity
KZA74_01920	COG1983	PspC domain protein
KZA74_01930	COG1960	acyl-CoA dehydrogenase activity
KZA74_01945	COG0408	coproporphyrinogen oxidase activity
KZA74_01965	COG0513	Belongs to the DEAD box helicase family
KZA74_01975	COG1127	ABC transporter
KZA74_01980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KZA74_01990	COG2854	intermembrane phospholipid transfer
KZA74_02000	COG0598	Magnesium transport protein CorA
KZA74_02010	COG0494	nUDIX hydrolase
KZA74_02015	COG1040	competence protein
KZA74_02020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KZA74_02040	COG1946	Acyl-CoA thioesterase
KZA74_02045	COG1301	dicarboxylic acid transport
KZA74_02060	COG1959	2 iron, 2 sulfur cluster binding
KZA74_02065	COG1017	nitric oxide dioxygenase activity
KZA74_02065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZA74_02075	COG0433	COG0433 Predicted ATPase
KZA74_02080	COG0626	cystathionine gamma-synthase activity
KZA74_02235	COG1960	acyl-CoA dehydrogenase activity
KZA74_02240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KZA74_02270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KZA74_02275	COG0339	signal peptide processing
KZA74_02280	COG0557	exoribonuclease II activity
KZA74_02325	COG0179	Fumarylacetoacetate (FAA) hydrolase
KZA74_02330	COG2169	Transcriptional regulator
KZA74_02335	COG0697	spore germination
KZA74_02340	COG1295	ribonuclease BN
KZA74_02375	COG1702	phosphate starvation-inducible protein PhoH
KZA74_02385	COG0741	lytic transglycosylase activity
KZA74_02385	COG1196	nuclear chromosome segregation
KZA74_02385	COG0739	heme binding
KZA74_02415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KZA74_02420	COG1183	phosphatidylcholine synthase activity
KZA74_02465	COG1960	acyl-CoA dehydrogenase activity
KZA74_02470	COG1309	transcriptional regulator
KZA74_02485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KZA74_02490	COG1960	acyl-CoA dehydrogenase activity
KZA74_02510	COG2969	positive regulation of protein catabolic process
KZA74_02520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KZA74_02530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KZA74_02535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KZA74_02540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KZA74_02560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KZA74_02570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KZA74_02585	COG2199	diguanylate cyclase activity
KZA74_02645	COG1607	acyl-coa hydrolase
KZA74_02675	COG3013	Belongs to the UPF0304 family
KZA74_02755	COG2205	protein histidine kinase activity
KZA74_02770	COG2132	Multicopper oxidase
KZA74_02795	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KZA74_02845	COG0582	viral genome integration into host DNA
KZA74_02870	COG2350	Protein conserved in bacteria
KZA74_02880	COG0613	PHP domain protein
KZA74_02885	COG3781	membrane
KZA74_02895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KZA74_02900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KZA74_02910	COG1862	Preprotein translocase
KZA74_02940	COG0582	viral genome integration into host DNA
KZA74_02965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KZA74_02980	COG2205	protein histidine kinase activity
KZA74_02985	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KZA74_03005	COG0726	polysaccharide deacetylase
KZA74_03010	COG0463	Glycosyl transferase, family 2
KZA74_03015	COG0438	transferase activity, transferring glycosyl groups
KZA74_03030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KZA74_03080	COG1960	acyl-CoA dehydrogenase activity
KZA74_03085	COG1960	acyl-CoA dehydrogenase activity
KZA74_03095	COG2205	protein histidine kinase activity
KZA74_03100	COG0745	RESPONSE REGULATOR receiver
KZA74_03105	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KZA74_03125	COG2096	Adenosyltransferase
KZA74_03130	COG4206	TonB-dependent receptor
KZA74_03175	COG0285	dihydrofolate synthase activity
KZA74_03195	COG0450	alkyl hydroperoxide reductase
KZA74_03210	COG0477	Major facilitator Superfamily
KZA74_03215	COG1272	protein, Hemolysin III
KZA74_03225	COG2153	protein acetylation
KZA74_03245	COG0183	Belongs to the thiolase family
KZA74_03250	COG2207	Transcriptional regulator
KZA74_03270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZA74_03290	COG0183	Belongs to the thiolase family
KZA74_03310	COG1690	Belongs to the RtcB family
KZA74_03315	COG0833	amino acid
KZA74_03325	COG2233	PERMEase
KZA74_03330	COG1217	gtp-binding protein TYPA
KZA74_03355	COG2094	Belongs to the DNA glycosylase MPG family
KZA74_03360	COG4772	TonB-dependent receptor
KZA74_03365	COG1902	pentaerythritol trinitrate reductase activity
KZA74_03380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KZA74_03385	COG0354	folic acid binding
KZA74_03395	COG3189	MarR family transcriptional regulator
KZA74_03400	COG2824	Alkylphosphonate utilization operon protein PhnA
KZA74_03405	COG3422	double-strand break repair
KZA74_03445	COG0840	transmembrane signaling receptor activity
KZA74_03465	COG5510	response to toxic substance
KZA74_03475	COG2832	Protein of unknown function (DUF454)
KZA74_03480	COG1376	ErfK ybiS ycfS ynhG family protein
KZA74_03520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KZA74_03530	COG1289	transmembrane transporter activity
KZA74_03535	COG2814	Major facilitator Superfamily
KZA74_03555	COG1115	amino acid carrier protein
KZA74_03560	COG1752	Esterase of the alpha-beta hydrolase superfamily
KZA74_03565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KZA74_03570	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KZA74_03575	COG3590	peptidase
KZA74_03600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KZA74_03610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KZA74_03615	COG1077	Cell shape determining protein MreB Mrl
KZA74_03620	COG1792	Involved in formation and maintenance of cell shape
KZA74_03625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KZA74_03630	COG0424	maF-like protein
KZA74_03635	COG1530	ribonuclease E activity
KZA74_03645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA74_03655	COG0560	Phosphoserine phosphatase
KZA74_03665	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZA74_03690	COG2207	Transcriptional regulator
KZA74_03710	COG1113	amino acid transport
KZA74_03715	COG2828	Protein conserved in bacteria
KZA74_03720	COG0142	geranyltranstransferase activity
KZA74_03725	COG2315	Protein conserved in bacteria
KZA74_03740	COG1752	Esterase of the alpha-beta hydrolase superfamily
KZA74_03760	COG2194	sulfuric ester hydrolase activity
KZA74_03765	COG0745	RESPONSE REGULATOR receiver
KZA74_03770	COG0642	Histidine kinase
KZA74_03780	COG0004	ammonium transporteR
KZA74_03785	COG0583	DNA-binding transcription factor activity
KZA74_03805	COG0525	valine-tRNA ligase activity
KZA74_03815	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_03825	COG0393	Putative heavy-metal-binding
KZA74_03830	COG0393	Putative heavy-metal-binding
KZA74_03835	COG1538	Outer membrane efflux protein
KZA74_03845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZA74_03850	COG0671	phosphoesterase, PA-phosphatase related
KZA74_03880	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KZA74_03895	COG1648	precorrin-2 dehydrogenase activity
KZA74_03895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KZA74_03900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KZA74_03905	COG1733	regulation of RNA biosynthetic process
KZA74_03915	COG0531	amino acid
KZA74_03930	COG0321	lipoyl(octanoyl) transferase activity
KZA74_03935	COG2921	Belongs to the UPF0250 family
KZA74_03975	COG2009	succinate dehydrogenase
KZA74_03980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KZA74_03985	COG1053	succinate dehydrogenase
KZA74_03990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KZA74_04015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZA74_04035	COG2354	Protein conserved in bacteria
KZA74_04040	COG2321	neutral zinc metallopeptidase
KZA74_04060	COG2843	Capsule synthesis protein
KZA74_04075	COG0589	response to stress
KZA74_04085	COG0251	oxidation-reduction process
KZA74_04090	COG1309	transcriptional regulator
KZA74_04105	COG0505	Belongs to the CarA family
KZA74_04130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KZA74_04135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KZA74_04185	COG0477	Major facilitator Superfamily
KZA74_04190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KZA74_04205	COG1597	lipid kinase activity
KZA74_04210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KZA74_04230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZA74_04235	COG0584	glycerophosphoryl diester phosphodiesterase
KZA74_04255	COG0741	lytic transglycosylase activity
KZA74_04275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KZA74_04290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA74_04300	COG3811	Belongs to the UPF0386 family
KZA74_04355	COG0778	Nitroreductase
KZA74_04370	COG1929	Belongs to the glycerate kinase type-1 family
KZA74_04375	COG0243	molybdopterin cofactor binding
KZA74_04380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KZA74_04385	COG3339	Conserved Protein
KZA74_04395	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KZA74_04410	COG1113	amino acid transport
KZA74_04420	COG0019	diaminopimelate decarboxylase activity
KZA74_04430	COG1280	lysine exporter protein (LysE YggA)
KZA74_04435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KZA74_04465	COG0463	Glycosyl transferase, family 2
KZA74_04485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZA74_04520	COG4591	ABC-type transport system involved in lipoprotein release permease component
KZA74_04525	COG1136	(ABC) transporter
KZA74_04530	COG0658	competence protein
KZA74_04530	COG2333	competence protein COMEC
KZA74_04540	COG0616	signal peptide processing
KZA74_04540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KZA74_04545	COG0596	Alpha beta hydrolase
KZA74_04550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KZA74_04560	COG0628	permease
KZA74_04595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KZA74_04615	COG0823	Involved in the tonB-independent uptake of proteins
KZA74_04635	COG0824	Thioesterase
KZA74_04640	COG1473	amidohydrolase
KZA74_04660	COG0047	phosphoribosylformylglycinamidine synthase activity
KZA74_04660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KZA74_04685	COG1169	isochorismate synthase
KZA74_04690	COG1535	isochorismatase
KZA74_04690	COG3433	isochorismatase activity
KZA74_04695	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_04700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA74_04705	COG3433	isochorismatase activity
KZA74_04705	COG2226	methyltransferase
KZA74_04705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA74_04710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA74_04715	COG1021	2,3-dihydroxybenzoate-AMP ligase
KZA74_04720	COG3486	L-lysine 6-monooxygenase (NADPH) activity
KZA74_04725	COG0019	diaminopimelate decarboxylase activity
KZA74_04745	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KZA74_04750	COG4774	siderophore transport
KZA74_04765	COG0534	Mate efflux family protein
KZA74_04775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZA74_04845	COG1024	Enoyl-CoA hydratase
KZA74_04850	COG1051	belongs to the nudix hydrolase family
KZA74_04850	COG1056	cytidyltransferase-related domain
KZA74_04860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KZA74_04875	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KZA74_04890	COG4625	pathogenesis
KZA74_04895	COG0583	DNA-binding transcription factor activity
KZA74_04900	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KZA74_04905	COG4208	sulfate ABC transporter
KZA74_04910	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KZA74_04920	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KZA74_04925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KZA74_04930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KZA74_04950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KZA74_04960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KZA74_04970	COG0681	Belongs to the peptidase S26 family
KZA74_04985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KZA74_04995	COG1381	Involved in DNA repair and RecF pathway recombination
KZA74_05000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KZA74_05010	COG4221	oxidoreductase activity
KZA74_05040	COG0443	Heat shock 70 kDa protein
KZA74_05050	COG0436	Aminotransferase
KZA74_05070	COG0556	nucleotide-excision repair
KZA74_05125	COG2070	2-Nitropropane dioxygenase
KZA74_05155	COG1215	transferase activity, transferring glycosyl groups
KZA74_05170	COG0415	Belongs to the DNA photolyase family
KZA74_05180	COG1252	NADH dehydrogenase
KZA74_05185	COG1686	Belongs to the peptidase S11 family
KZA74_05200	COG1187	pseudouridine synthase activity
KZA74_05225	COG0477	Major facilitator Superfamily
KZA74_05230	COG0583	DNA-binding transcription factor activity
KZA74_05235	COG1823	symporter activity
KZA74_05245	COG0612	Peptidase, M16
KZA74_05270	COG0352	thiamine-phosphate diphosphorylase activity
KZA74_05305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZA74_05315	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZA74_05330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KZA74_05335	COG0076	glutamate decarboxylase activity
KZA74_05345	COG1522	sequence-specific DNA binding
KZA74_05350	COG3961	Belongs to the TPP enzyme family
KZA74_05355	COG1113	amino acid transport
KZA74_05360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KZA74_05365	COG0573	inorganic phosphate transmembrane transporter activity
KZA74_05375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KZA74_05380	COG0616	signal peptide processing
KZA74_05415	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KZA74_05420	COG1686	Belongs to the peptidase S11 family
KZA74_05445	COG0583	DNA-binding transcription factor activity
KZA74_05450	COG1067	ATP-dependent peptidase activity
KZA74_05475	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KZA74_05495	COG1966	Carbon starvation protein
KZA74_05500	COG2879	small protein
KZA74_05540	COG1335	isochorismatase
KZA74_05545	COG0583	DNA-binding transcription factor activity
KZA74_05560	COG0596	Alpha beta hydrolase
KZA74_05570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KZA74_05610	COG1741	Belongs to the pirin family
KZA74_05620	COG2964	Protein conserved in bacteria
KZA74_05635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA74_05640	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZA74_05645	COG4605	iron ion homeostasis
KZA74_05650	COG4604	ABC transporter, ATP-binding protein
KZA74_05655	COG4607	ABC-type enterochelin transport system periplasmic component
KZA74_05660	COG4774	siderophore transport
KZA74_05670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZA74_05675	COG1021	2,3-dihydroxybenzoate-AMP ligase
KZA74_05680	COG3433	isochorismatase activity
KZA74_05680	COG1535	isochorismatase
KZA74_05690	COG1132	(ABC) transporter
KZA74_05695	COG1132	(ABC) transporter
KZA74_05700	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KZA74_05725	COG3739	integral membrane protein
KZA74_05745	COG0302	gtp cyclohydrolase
KZA74_05755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KZA74_05785	COG0308	aminopeptidase N
KZA74_05790	COG0512	Glutamine amidotransferase of anthranilate synthase
KZA74_05805	COG0174	glutamine synthetase
KZA74_05815	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KZA74_05850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KZA74_05855	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KZA74_05860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KZA74_05880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KZA74_05885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KZA74_05890	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KZA74_05905	COG1960	acyl-CoA dehydrogenase activity
KZA74_05910	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KZA74_05915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZA74_05925	COG2223	nitrite transmembrane transporter activity
KZA74_05935	COG0024	Methionine aminopeptidase
KZA74_05940	COG0052	Belongs to the universal ribosomal protein uS2 family
KZA74_05955	COG2207	Transcriptional regulator
KZA74_05980	COG2951	lytic endotransglycosylase activity
KZA74_05985	COG0772	Belongs to the SEDS family
KZA74_06000	COG0842	Transport permease protein
KZA74_06005	COG1131	(ABC) transporter
KZA74_06050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZA74_06065	COG4215	(ABC) transporter
KZA74_06070	COG4160	amino acid transport
KZA74_06075	COG4598	ABC transporter
KZA74_06085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KZA74_06090	COG0826	peptidase U32
KZA74_06095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA74_06110	COG1720	tRNA m6t6A37 methyltransferase activity
KZA74_06120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KZA74_06135	COG0642	Histidine kinase
KZA74_06145	COG0494	nUDIX hydrolase
KZA74_06155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KZA74_06160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KZA74_06165	COG3139	Protein of unknown function (DUF1315)
KZA74_06170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KZA74_06175	COG1301	dicarboxylic acid transport
KZA74_06180	COG1960	acyl-CoA dehydrogenase activity
KZA74_06185	COG2819	hydrolase of the alpha beta superfamily
KZA74_06195	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KZA74_06205	COG2195	Cleaves the N-terminal amino acid of tripeptides
KZA74_06225	COG1690	Belongs to the RtcB family
KZA74_06230	COG1234	tRNA 3'-trailer cleavage
KZA74_06235	COG4650	regulator
KZA74_06265	COG2363	Small membrane protein
KZA74_06285	COG0513	Belongs to the DEAD box helicase family
KZA74_06295	COG0778	Nitroreductase
KZA74_06325	COG1286	toxin biosynthetic process
KZA74_06350	COG4783	chaperone-mediated protein folding
KZA74_06355	COG1610	YqeY-like protein
KZA74_06385	COG0515	serine threonine protein kinase
KZA74_06385	COG2815	serine threonine protein kinase
KZA74_06455	COG3111	PFAM Bacterial OB fold (BOF) protein
KZA74_06480	COG3243	poly(R)-hydroxyalkanoic acid synthase
KZA74_06485	COG0786	glutamate:sodium symporter activity
KZA74_06495	COG2186	Transcriptional regulator
KZA74_06545	COG0477	Major facilitator Superfamily
KZA74_06550	COG1051	belongs to the nudix hydrolase family
KZA74_06580	COG2995	paraquat-inducible protein a
KZA74_06585	COG3008	intermembrane lipid transfer
KZA74_06585	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KZA74_06600	COG1794	racemase activity, acting on amino acids and derivatives
KZA74_06630	COG1301	dicarboxylic acid transport
KZA74_06640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZA74_06645	COG2011	ABC-type metal ion transport system permease component
KZA74_06650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KZA74_06655	COG1464	Belongs to the NlpA lipoprotein family
KZA74_06660	COG0151	Belongs to the GarS family
KZA74_06665	COG0138	bifunctional purine biosynthesis protein purh
KZA74_06670	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KZA74_06700	COG2308	Evidence 4 Homologs of previously reported genes of
KZA74_06710	COG1305	Transglutaminase-like
KZA74_06720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KZA74_06725	COG0305	Participates in initiation and elongation during chromosome replication
KZA74_06750	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KZA74_06760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KZA74_06765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KZA74_06790	COG0726	polysaccharide deacetylase
KZA74_06790	COG1649	PFAM Uncharacterised BCR, COG1649
KZA74_06795	COG1215	transferase activity, transferring glycosyl groups
KZA74_06800	COG3658	cytochrome
KZA74_06810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZA74_06825	COG0583	DNA-binding transcription factor activity
KZA74_06855	COG1960	acyl-CoA dehydrogenase activity
KZA74_06860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZA74_06865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZA74_06880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KZA74_06890	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KZA74_06895	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KZA74_06900	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KZA74_06905	COG2205	protein histidine kinase activity
KZA74_06910	COG0745	RESPONSE REGULATOR receiver
KZA74_06915	COG0174	glutamine synthetase
KZA74_06935	COG0729	surface antigen
KZA74_06960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KZA74_06965	COG2814	Major facilitator Superfamily
KZA74_06980	COG0583	DNA-binding transcription factor activity
KZA74_06995	COG1187	pseudouridine synthase activity
KZA74_07015	COG0802	atpase or kinase
KZA74_07020	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KZA74_07030	COG1923	regulation of RNA biosynthetic process
KZA74_07035	COG0697	spore germination
KZA74_07060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KZA74_07065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KZA74_07065	COG0519	Catalyzes the synthesis of GMP from XMP
KZA74_07070	COG4302	ethanolamine ammonia-lyase activity
KZA74_07075	COG4303	Ethanolamine ammonia lyase large subunit
KZA74_07080	COG0531	amino acid
KZA74_07100	COG1454	alcohol dehydrogenase
KZA74_07105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KZA74_07130	COG0308	aminopeptidase N
KZA74_07170	COG1605	Chorismate mutase
KZA74_07185	COG1309	transcriptional regulator
KZA74_07195	COG0668	transmembrane transport
KZA74_07225	COG4773	Receptor
KZA74_07245	COG0488	(ABC) transporter
KZA74_07250	COG0589	response to stress
KZA74_07275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KZA74_07285	COG3135	benzoate transporter
KZA74_07290	COG1522	sequence-specific DNA binding
KZA74_07300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KZA74_07305	COG0583	DNA-binding transcription factor activity
KZA74_07315	COG0183	Belongs to the thiolase family
KZA74_07325	COG2030	dehydratase
KZA74_07330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KZA74_07345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KZA74_07355	COG0824	Thioesterase
KZA74_07360	COG1454	alcohol dehydrogenase
KZA74_07370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KZA74_07390	COG0069	glutamate synthase activity
KZA74_07535	COG3617	BRO family, N-terminal domain
KZA74_07575	COG5410	chromosome segregation
KZA74_07680	COG1598	PFAM Uncharacterised protein family UPF0150
KZA74_07750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KZA74_07765	COG2814	Major facilitator Superfamily
KZA74_07780	COG0511	ligase activity, forming carbon-carbon bonds
KZA74_07800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZA74_07800	COG1116	anion transmembrane transporter activity
KZA74_07805	COG0745	RESPONSE REGULATOR receiver
KZA74_07815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZA74_07815	COG2146	nitrite reductase [NAD(P)H] activity
KZA74_07820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZA74_07825	COG0243	molybdopterin cofactor binding
KZA74_07835	COG0243	molybdopterin cofactor binding
KZA74_07840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KZA74_07855	COG0521	Mo-molybdopterin cofactor biosynthetic process
KZA74_07855	COG0315	cyclic pyranopterin monophosphate synthase activity
KZA74_07860	COG0303	'Molybdopterin
KZA74_07870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA74_07875	COG0697	spore germination
KZA74_07895	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KZA74_07900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KZA74_07955	COG2204	response regulator
KZA74_07960	COG3852	Histidine kinase
KZA74_07985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KZA74_07990	COG0575	Belongs to the CDS family
KZA74_08005	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KZA74_08025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KZA74_08040	COG2137	regulation of response to DNA damage stimulus
KZA74_08050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KZA74_08055	COG1011	Hydrolase
KZA74_08080	COG1522	sequence-specific DNA binding
KZA74_08090	COG1113	amino acid transport
KZA74_08105	COG0659	secondary active sulfate transmembrane transporter activity
KZA74_08110	COG2135	peptidase activity
KZA74_08125	COG3300	MHYT domain
KZA74_08125	COG5001	Diguanylate cyclase
KZA74_08140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KZA74_08140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KZA74_08140	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KZA74_08145	COG1105	Belongs to the carbohydrate kinase PfkB family
KZA74_08150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZA74_08150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KZA74_08180	COG0024	Methionine aminopeptidase
KZA74_08185	COG0583	DNA-binding transcription factor activity
KZA74_08195	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KZA74_08200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KZA74_08205	COG0516	GMP reductase activity
KZA74_08205	COG0517	IMP dehydrogenase activity
KZA74_08230	COG0552	protein localization to endoplasmic reticulum
KZA74_08240	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KZA74_08255	COG4890	Cyd operon protein YbgT
KZA74_08260	COG1294	oxidase, subunit
KZA74_08275	COG1585	Membrane protein implicated in regulation of membrane protease activity
KZA74_08285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KZA74_08290	COG4774	siderophore transport
KZA74_08305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KZA74_08310	COG0569	domain protein
KZA74_08315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KZA74_08345	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KZA74_08350	COG0542	response to heat
KZA74_08375	COG1902	pentaerythritol trinitrate reductase activity
KZA74_08375	COG0446	pyridine nucleotide-disulphide oxidoreductase
KZA74_08420	COG2323	membrane
KZA74_08425	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KZA74_08435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KZA74_08440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KZA74_08445	COG0183	Belongs to the thiolase family
KZA74_08450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KZA74_08455	COG0596	Alpha beta hydrolase
KZA74_08460	COG2271	Major facilitator Superfamily
KZA74_08465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KZA74_08470	COG3485	protocatechuate 3,4-dioxygenase
KZA74_08475	COG3485	protocatechuate 3,4-dioxygenase
KZA74_08480	COG0710	3-dehydroquinate dehydratase activity
KZA74_08485	COG3420	alginic acid biosynthetic process
KZA74_08490	COG3659	wide pore channel activity
KZA74_08495	COG4993	Dehydrogenase
KZA74_08505	COG2391	methyltransferase activity
KZA74_08520	COG1414	Transcriptional regulator
KZA74_08525	COG0583	DNA-binding transcription factor activity
KZA74_08530	COG1960	acyl-CoA dehydrogenase activity
KZA74_08555	COG2814	Major facilitator Superfamily
KZA74_08565	COG0154	amidase activity
KZA74_08585	COG4638	Rieske (2fe-2S)
KZA74_08595	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_08605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZA74_08615	COG3733	amine oxidase
KZA74_08625	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_08635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KZA74_08640	COG0183	Belongs to the thiolase family
KZA74_08645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KZA74_08650	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KZA74_08660	COG4829	muconolactone delta-isomerase
KZA74_08665	COG4948	Mandelate Racemase Muconate Lactonizing
KZA74_08670	COG0583	DNA-binding transcription factor activity
KZA74_08680	COG2186	Transcriptional regulator
KZA74_08700	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_08715	COG0446	pyridine nucleotide-disulphide oxidoreductase
KZA74_08715	COG1902	pentaerythritol trinitrate reductase activity
KZA74_08725	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KZA74_08735	COG0789	Transcriptional regulator
KZA74_08760	COG1309	transcriptional regulator
KZA74_08765	COG0583	DNA-binding transcription factor activity
KZA74_08770	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_08775	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_08780	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_08790	COG1960	acyl-CoA dehydrogenase activity
KZA74_08800	COG0318	PFAM AMP-dependent synthetase and ligase
KZA74_08875	COG2188	Transcriptional regulator
KZA74_08890	COG0583	DNA-binding transcription factor activity
KZA74_08905	COG1566	PFAM secretion protein HlyD family protein
KZA74_08920	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_08925	COG0129	dihydroxy-acid dehydratase activity
KZA74_08935	COG0583	DNA-binding transcription factor activity
KZA74_08940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KZA74_08950	COG2084	Dehydrogenase
KZA74_08955	COG2207	Transcriptional regulator
KZA74_08960	COG1064	alcohol dehydrogenase
KZA74_08970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZA74_08975	COG1120	ATPase activity
KZA74_09070	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KZA74_09105	COG2856	Zn peptidase
KZA74_09155	COG2207	Transcriptional regulator
KZA74_09170	COG2205	protein histidine kinase activity
KZA74_09175	COG0745	RESPONSE REGULATOR receiver
KZA74_09180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZA74_09185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KZA74_09265	COG3539	Fimbrial protein
KZA74_09290	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KZA74_09300	COG0753	catalase activity
KZA74_09315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KZA74_09375	COG1535	isochorismatase
KZA74_09375	COG3433	isochorismatase activity
KZA74_09380	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_09385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KZA74_09390	COG4149	molybdate abc transporter
KZA74_09395	COG0725	ABC transporter, periplasmic molybdate-binding protein
KZA74_09405	COG4638	Rieske (2fe-2S)
KZA74_09410	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KZA74_09415	COG0543	2 iron, 2 sulfur cluster binding
KZA74_09415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZA74_09430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZA74_09440	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_09455	COG2207	Transcriptional regulator
KZA74_09460	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_09465	COG2610	gluconate transmembrane transporter activity
KZA74_09475	COG1309	transcriptional regulator
KZA74_09495	COG0583	DNA-binding transcription factor activity
KZA74_09510	COG2031	fatty acid transporter
KZA74_09515	COG0183	Belongs to the thiolase family
KZA74_09520	COG0583	DNA-binding transcription factor activity
KZA74_09525	COG0583	DNA-binding transcription factor activity
KZA74_09540	COG1027	Aspartate ammonia-lyase
KZA74_09550	COG0477	Major facilitator Superfamily
KZA74_09570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZA74_09575	COG4521	taurine ABC transporter
KZA74_09590	COG2188	Transcriptional regulator
KZA74_09600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KZA74_09605	COG1733	regulation of RNA biosynthetic process
KZA74_09610	COG3708	Transcriptional regulator
KZA74_09610	COG2207	Transcriptional regulator
KZA74_09625	COG0730	response to heat
KZA74_09635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZA74_09635	COG3453	Protein conserved in bacteria
KZA74_09645	COG3781	membrane
KZA74_09650	COG1063	alcohol dehydrogenase
KZA74_09660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZA74_09665	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZA74_09670	COG0022	dehydrogenase e1 component
KZA74_09675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KZA74_09680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KZA74_09695	COG3706	GGDEF domain
KZA74_09710	COG0133	tryptophan synthase activity
KZA74_09720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KZA74_09750	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KZA74_09755	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KZA74_09780	COG2226	methyltransferase
KZA74_09835	COG0842	Transport permease protein
KZA74_09840	COG0842	Transport permease protein
KZA74_09845	COG1131	(ABC) transporter
KZA74_09860	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KZA74_09865	COG4773	Receptor
KZA74_09885	COG0730	response to heat
KZA74_09890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KZA74_09905	COG0406	alpha-ribazole phosphatase activity
KZA74_09910	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KZA74_09925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KZA74_09955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KZA74_09965	COG4264	IucA IucC family
KZA74_09970	COG4264	IucA IucC family
KZA74_09975	COG2814	Major facilitator Superfamily
KZA74_09990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KZA74_10005	COG1960	acyl-CoA dehydrogenase activity
KZA74_10010	COG1960	acyl-CoA dehydrogenase activity
KZA74_10015	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KZA74_10020	COG2207	Transcriptional regulator
KZA74_10025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KZA74_10030	COG0776	regulation of translation
KZA74_10055	COG0822	iron-sulfur transferase activity
KZA74_10060	COG0316	Belongs to the HesB IscA family
KZA74_10090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KZA74_10110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KZA74_10115	COG0702	epimerase
KZA74_10150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KZA74_10160	COG0339	signal peptide processing
KZA74_10210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KZA74_10315	COG4695	Portal protein
KZA74_10470	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KZA74_10500	COG0776	regulation of translation
KZA74_10565	COG0084	hydrolase, TatD family'
KZA74_10585	COG1663	tetraacyldisaccharide 4'-kinase activity
KZA74_10590	COG1132	(ABC) transporter
KZA74_10600	COG0811	peptide transport
KZA74_10605	COG1475	DNA binding
KZA74_10610	COG1192	Involved in chromosome partitioning
KZA74_10620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KZA74_10635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KZA74_10640	COG0191	fructose-bisphosphate aldolase activity
KZA74_10660	COG0424	maF-like protein
KZA74_10665	COG2850	peptidyl-arginine hydroxylation
KZA74_10675	COG0640	Transcriptional regulator
KZA74_10685	COG3619	membrane
KZA74_10690	COG3122	Protein conserved in bacteria
KZA74_10695	COG1132	(ABC) transporter
KZA74_10715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KZA74_10720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KZA74_10730	COG0506	proline dehydrogenase activity
KZA74_10730	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KZA74_10730	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KZA74_10735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KZA74_10750	COG3698	Phosphodiester glycosidase
KZA74_10760	COG2353	YceI-like domain
KZA74_10770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KZA74_10815	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KZA74_10815	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KZA74_10840	COG3539	Fimbrial protein
KZA74_10845	COG3121	Chaperone
KZA74_10870	COG0697	spore germination
KZA74_10880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KZA74_10890	COG0583	DNA-binding transcription factor activity
KZA74_10910	COG1309	transcriptional regulator
KZA74_10925	COG1522	sequence-specific DNA binding
KZA74_10935	COG1126	abc transporter atp-binding protein
KZA74_10940	COG0765	amino acid transport
KZA74_10945	COG0765	amino acid transport
KZA74_10975	COG1464	Belongs to the NlpA lipoprotein family
KZA74_10985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KZA74_10990	COG2011	ABC-type metal ion transport system permease component
KZA74_10995	COG0012	GTP binding
KZA74_11020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KZA74_11060	COG0386	Belongs to the glutathione peroxidase family
KZA74_11070	COG0436	Aminotransferase
KZA74_11075	COG1301	dicarboxylic acid transport
KZA74_11110	COG3634	alkyl hydroperoxide reductase activity
KZA74_11125	COG0583	DNA-binding transcription factor activity
KZA74_11130	COG0798	PFAM Bile acid sodium symporter
KZA74_11135	COG0640	Transcriptional regulator
KZA74_11150	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KZA74_11160	COG0583	DNA-binding transcription factor activity
KZA74_11170	COG1953	Uracil, thiamine, allantoin
KZA74_11180	COG2175	clavaminate synthase activity
KZA74_11185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZA74_11190	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KZA74_11195	COG4521	taurine ABC transporter
KZA74_11205	COG0477	Major facilitator Superfamily
KZA74_11225	COG1271	oxidase subunit
KZA74_11230	COG1294	oxidase, subunit
KZA74_11240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA74_11260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KZA74_11280	COG3052	prosthetic group binding
KZA74_11285	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KZA74_11295	COG0583	DNA-binding transcription factor activity
KZA74_11305	COG2814	Major facilitator Superfamily
KZA74_11320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA74_11325	COG1346	cytolysis
KZA74_11335	COG0583	DNA-binding transcription factor activity
KZA74_11340	COG0625	glutathione transferase activity
KZA74_11345	COG0625	glutathione transferase activity
KZA74_11350	COG0583	DNA-binding transcription factor activity
KZA74_11365	COG1045	serine acetyltransferase
KZA74_11370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KZA74_11375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KZA74_11400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZA74_11405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZA74_11415	COG0765	amino acid transport
KZA74_11420	COG0765	amino acid transport
KZA74_11440	COG0784	Response regulator, receiver
KZA74_11440	COG2205	protein histidine kinase activity
KZA74_11480	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_11530	COG0583	DNA-binding transcription factor activity
KZA74_11550	COG0318	PFAM AMP-dependent synthetase and ligase
KZA74_11555	COG1309	transcriptional regulator
KZA74_11560	COG1960	acyl-CoA dehydrogenase activity
KZA74_11565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KZA74_11570	COG1024	Enoyl-CoA hydratase
KZA74_11575	COG4770	biotin carboxylase activity
KZA74_11585	COG0583	DNA-binding transcription factor activity
KZA74_11605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KZA74_11610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KZA74_11625	COG3842	ATPase activity
KZA74_11630	COG1840	ABC-type Fe3 transport system, periplasmic component
KZA74_11645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZA74_11650	COG1414	Transcriptional regulator
KZA74_11660	COG0583	DNA-binding transcription factor activity
KZA74_11665	COG3038	cytochrome b561
KZA74_11670	COG0753	catalase activity
KZA74_11700	COG2050	protein possibly involved in aromatic compounds catabolism
KZA74_11710	COG3327	negative regulation of DNA-templated transcription, initiation
KZA74_11715	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KZA74_11720	COG0183	Belongs to the thiolase family
KZA74_11725	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZA74_11730	COG1024	Enoyl-CoA hydratase
KZA74_11735	COG1024	Enoyl-CoA hydratase
KZA74_11740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZA74_11745	COG2151	metal-sulfur cluster biosynthetic enzyme
KZA74_11750	COG3396	Phenylacetate-CoA oxygenase
KZA74_11755	COG3460	Phenylacetate-CoA oxygenase
KZA74_11760	COG3396	Phenylacetate-CoA oxygenase
KZA74_11765	COG2030	dehydratase
KZA74_11765	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_11770	COG1760	l-serine dehydratase
KZA74_11775	COG0531	amino acid
KZA74_11780	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_11805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZA74_11825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KZA74_11835	COG0789	Transcriptional regulator
KZA74_11845	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KZA74_11860	COG2807	transmembrane transport
KZA74_11865	COG0590	tRNA wobble adenosine to inosine editing
KZA74_11970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KZA74_11995	COG1116	anion transmembrane transporter activity
KZA74_12000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZA74_12010	COG0864	Transcriptional regulator
KZA74_12025	COG1733	regulation of RNA biosynthetic process
KZA74_12030	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZA74_12035	COG0439	Biotin carboxylase
KZA74_12050	COG1063	alcohol dehydrogenase
KZA74_12060	COG1309	transcriptional regulator
KZA74_12070	COG0038	chloride channel
KZA74_12075	COG4770	biotin carboxylase activity
KZA74_12095	COG1914	H( )-stimulated, divalent metal cation uptake system
KZA74_12100	COG0583	DNA-binding transcription factor activity
KZA74_12135	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZA74_12155	COG2814	Major facilitator Superfamily
KZA74_12170	COG0598	Magnesium transport protein CorA
KZA74_12175	COG1560	Kdo2-lipid A biosynthetic process
KZA74_12190	COG1522	sequence-specific DNA binding
KZA74_12205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KZA74_12215	COG4122	O-methyltransferase activity
KZA74_12245	COG1538	Outer membrane efflux protein
KZA74_12250	COG1137	ATPase activity
KZA74_12255	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KZA74_12265	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KZA74_12270	COG0517	IMP dehydrogenase activity
KZA74_12270	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KZA74_12305	COG2814	Major facilitator Superfamily
KZA74_12340	COG1278	Cold shock
KZA74_12345	COG1280	lysine exporter protein (LysE YggA)
KZA74_12375	COG1570	exodeoxyribonuclease VII activity
KZA74_12425	COG0583	DNA-binding transcription factor activity
KZA74_12430	COG4638	Rieske (2fe-2S)
KZA74_12435	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KZA74_12440	COG0543	2 iron, 2 sulfur cluster binding
KZA74_12440	COG0633	Ferredoxin
KZA74_12445	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_12450	COG3135	benzoate transporter
KZA74_12455	COG2814	Major facilitator Superfamily
KZA74_12470	COG1643	Atp-dependent helicase
KZA74_12475	COG0450	alkyl hydroperoxide reductase
KZA74_12485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KZA74_12495	COG3634	alkyl hydroperoxide reductase activity
KZA74_12515	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KZA74_12520	COG0625	glutathione transferase activity
KZA74_12530	COG2885	chlorophyll binding
KZA74_12565	COG0542	response to heat
KZA74_12580	COG1765	OsmC-like protein
KZA74_12595	COG0667	Aldo Keto reductase
KZA74_12610	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KZA74_12630	COG0582	viral genome integration into host DNA
KZA74_12765	COG3566	protein conserved in bacteria
KZA74_12785	COG3567	Phage-associated protein, HI1409 family
KZA74_12790	COG5410	chromosome segregation
KZA74_12870	COG4197	protein conserved in bacteria, prophage-related
KZA74_12875	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KZA74_12925	COG0527	aspartate kinase activity
KZA74_12935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KZA74_12945	COG3038	cytochrome b561
KZA74_12950	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KZA74_12955	COG2252	PERMEase
KZA74_12965	COG2072	flavoprotein involved in K transport
KZA74_12980	COG1741	Belongs to the pirin family
KZA74_12985	COG1309	transcriptional regulator
KZA74_12995	COG0300	oxidoreductase activity
KZA74_13000	COG2072	flavoprotein involved in K transport
KZA74_13005	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KZA74_13050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZA74_13065	COG2814	Major facilitator Superfamily
KZA74_13070	COG1024	Enoyl-CoA hydratase
KZA74_13075	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_13085	COG1960	acyl-CoA dehydrogenase activity
KZA74_13110	COG2186	Transcriptional regulator
KZA74_13115	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_13125	COG4948	Mandelate Racemase Muconate Lactonizing
KZA74_13130	COG2271	Major facilitator Superfamily
KZA74_13135	COG2721	sulfolactate sulfo-lyase activity
KZA74_13140	COG0697	spore germination
KZA74_13170	COG1113	amino acid transport
KZA74_13190	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_13210	COG0531	amino acid
KZA74_13220	COG1113	amino acid transport
KZA74_13265	COG0583	DNA-binding transcription factor activity
KZA74_13275	COG0251	oxidation-reduction process
KZA74_13310	COG1902	pentaerythritol trinitrate reductase activity
KZA74_13310	COG0446	pyridine nucleotide-disulphide oxidoreductase
KZA74_13325	COG4251	negative regulation of phosphorylation
KZA74_13325	COG5001	Diguanylate cyclase
KZA74_13325	COG2203	Gaf domain
KZA74_13325	COG3706	GGDEF domain
KZA74_13335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KZA74_13355	COG4172	Belongs to the ABC transporter superfamily
KZA74_13360	COG4239	(ABC) transporter, permease
KZA74_13365	COG4174	ABC transporter (Permease)
KZA74_13375	COG1388	LysM domain
KZA74_13375	COG1388	LysM domain
KZA74_13375	COG0741	lytic transglycosylase activity
KZA74_13375	COG0741	lytic transglycosylase activity
KZA74_13380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KZA74_13420	COG0583	DNA-binding transcription factor activity
KZA74_13425	COG1279	arginine transmembrane transporter activity
KZA74_13445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZA74_13450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZA74_13455	COG0006	proline dipeptidase activity
KZA74_13495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KZA74_13520	COG3384	dioxygenase
KZA74_13530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KZA74_13535	COG2878	Part of a membrane complex involved in electron transport
KZA74_13540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KZA74_13565	COG0768	penicillin binding
KZA74_13570	COG0742	ribosomal rna small subunit methyltransferase
KZA74_13585	COG0830	nickel cation binding
KZA74_13595	COG0804	urea catabolic process
KZA74_13640	COG1253	flavin adenine dinucleotide binding
KZA74_13645	COG2851	Citrate transporter
KZA74_13695	COG1773	rubredoxin
KZA74_13700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZA74_13710	COG0583	DNA-binding transcription factor activity
KZA74_13740	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KZA74_13745	COG4181	ATPase activity
KZA74_13790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KZA74_13810	COG0306	phosphate transporter
KZA74_13825	COG3958	Transketolase
KZA74_13830	COG3959	Transketolase, thiamine diphosphate binding domain
KZA74_13835	COG2271	Major facilitator Superfamily
KZA74_13840	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_13845	COG0583	DNA-binding transcription factor activity
KZA74_13865	COG2223	nitrite transmembrane transporter activity
KZA74_13870	COG2207	Transcriptional regulator
KZA74_13875	COG2066	Belongs to the glutaminase family
KZA74_13880	COG0242	peptide deformylase activity
KZA74_13885	COG0477	Major facilitator Superfamily
KZA74_13895	COG0028	Belongs to the TPP enzyme family
KZA74_13910	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_13915	COG2267	carboxylic ester hydrolase activity
KZA74_13925	COG2271	Major facilitator Superfamily
KZA74_13930	COG0446	pyridine nucleotide-disulphide oxidoreductase
KZA74_13940	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_13960	COG1414	Transcriptional regulator
KZA74_13975	COG1024	Enoyl-CoA hydratase
KZA74_13985	COG1215	transferase activity, transferring glycosyl groups
KZA74_13990	COG0726	polysaccharide deacetylase
KZA74_13990	COG1649	PFAM Uncharacterised BCR, COG1649
KZA74_14000	COG4681	YaeQ
KZA74_14010	COG0523	cobalamin synthesis protein
KZA74_14020	COG1607	acyl-coa hydrolase
KZA74_14030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KZA74_14035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KZA74_14040	COG1309	transcriptional regulator
KZA74_14065	COG2040	homocysteine
KZA74_14070	COG0531	amino acid
KZA74_14095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KZA74_14100	COG0477	Major facilitator Superfamily
KZA74_14140	COG0405	Gamma-glutamyltransferase
KZA74_14145	COG2814	Major facilitator Superfamily
KZA74_14155	COG2050	protein possibly involved in aromatic compounds catabolism
KZA74_14170	COG1090	epimerase
KZA74_14190	COG0420	3'-5' exonuclease activity
KZA74_14215	COG0735	belongs to the Fur family
KZA74_14220	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KZA74_14240	COG0121	glutamine amidotransferase
KZA74_14255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KZA74_14265	COG0210	DNA helicase
KZA74_14270	COG2885	chlorophyll binding
KZA74_14275	COG0204	Acyl-transferase
KZA74_14290	COG2894	cell division
KZA74_14305	COG1280	lysine exporter protein (LysE YggA)
KZA74_14310	COG1674	ftsk spoiiie
KZA74_14310	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KZA74_14315	COG0492	ferredoxin-NADP+ reductase activity
KZA74_14320	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KZA74_14330	COG0456	acetyltransferase
KZA74_14375	COG1981	membrane
KZA74_14390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KZA74_14390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KZA74_14410	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_14420	COG0657	acetylesterase activity
KZA74_14430	COG0473	3-isopropylmalate dehydrogenase activity
KZA74_14435	COG0583	DNA-binding transcription factor activity
KZA74_14455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KZA74_14480	COG0564	pseudouridine synthase activity
KZA74_14490	COG0358	DNA primase activity
KZA74_14505	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KZA74_14535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KZA74_14565	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KZA74_14575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KZA74_14575	COG0351	phosphomethylpyrimidine kinase
KZA74_14575	COG0352	thiamine-phosphate diphosphorylase activity
KZA74_14580	COG1652	LysM domain
KZA74_14605	COG1399	metal-binding, possibly nucleic acid-binding protein
KZA74_14610	COG3101	peptidyl-lysine hydroxylation
KZA74_14615	COG0009	L-threonylcarbamoyladenylate synthase
KZA74_14620	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KZA74_14625	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KZA74_14640	COG4106	trans-aconitate 2-methyltransferase activity
KZA74_14655	COG0596	Alpha beta hydrolase
KZA74_14655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KZA74_14655	COG2226	methyltransferase
KZA74_14660	COG1877	trehalose-phosphatase activity
KZA74_14665	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KZA74_14670	COG2223	nitrite transmembrane transporter activity
KZA74_14690	COG1196	nuclear chromosome segregation
KZA74_14700	COG0730	response to heat
KZA74_14715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KZA74_14725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KZA74_14775	COG0489	protein tyrosine kinase activity
KZA74_14785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZA74_14785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZA74_14815	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KZA74_14820	COG2081	HI0933 family
KZA74_14830	COG0668	transmembrane transport
KZA74_14850	COG0583	DNA-binding transcription factor activity
KZA74_14875	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KZA74_14880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KZA74_14910	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KZA74_14950	COG0745	RESPONSE REGULATOR receiver
KZA74_14965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KZA74_15010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZA74_15025	COG0583	DNA-binding transcription factor activity
KZA74_15055	COG0583	DNA-binding transcription factor activity
KZA74_15070	COG0583	DNA-binding transcription factor activity
KZA74_15075	COG1053	succinate dehydrogenase
KZA74_15085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KZA74_15090	COG2814	Major facilitator Superfamily
KZA74_15095	COG1960	acyl-CoA dehydrogenase activity
KZA74_15100	COG0583	DNA-binding transcription factor activity
KZA74_15105	COG1063	alcohol dehydrogenase
KZA74_15135	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KZA74_15140	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KZA74_15145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KZA74_15165	COG2132	Multicopper oxidase
KZA74_15175	COG0561	phosphatase activity
KZA74_15180	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KZA74_15205	COG1214	PFAM Peptidase M22, glycoprotease
KZA74_15255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KZA74_15265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KZA74_15270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KZA74_15275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KZA74_15335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KZA74_15345	COG1846	Transcriptional regulator
KZA74_15350	COG1764	response to oxidative stress
KZA74_15390	COG0037	tRNA processing
KZA74_15400	COG0248	Ppx GppA phosphatase
KZA74_15430	COG0072	phenylalanine-tRNA ligase activity
KZA74_15470	COG1238	metal cluster binding
KZA74_15475	COG0625	glutathione transferase activity
KZA74_15490	COG0318	PFAM AMP-dependent synthetase and ligase
KZA74_15495	COG3028	Belongs to the UPF0307 family
KZA74_15500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZA74_15520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KZA74_15525	COG0617	tRNA 3'-terminal CCA addition
KZA74_15530	COG1555	photosystem II stabilization
KZA74_15535	COG3956	TIGRFAM MazG family protein
KZA74_15545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KZA74_15565	COG0784	Response regulator, receiver
KZA74_15565	COG2205	protein histidine kinase activity
KZA74_15565	COG5002	protein histidine kinase activity
KZA74_15570	COG1024	Enoyl-CoA hydratase
KZA74_15575	COG2084	Dehydrogenase
KZA74_15580	COG3622	Belongs to the hyi family
KZA74_15610	COG0697	spore germination
KZA74_15620	COG2814	Major facilitator Superfamily
KZA74_15625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KZA74_15635	COG0583	DNA-binding transcription factor activity
KZA74_15645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KZA74_15655	COG0084	hydrolase, TatD family'
KZA74_15670	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KZA74_15720	COG0440	acetolactate synthase activity
KZA74_15725	COG0028	Belongs to the TPP enzyme family
KZA74_15750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZA74_15755	COG1136	(ABC) transporter
KZA74_15755	COG0577	efflux transmembrane transporter activity
KZA74_15760	COG1538	Outer membrane efflux protein
KZA74_15775	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KZA74_15780	COG1162	GTPase activity
KZA74_15790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KZA74_15810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KZA74_15815	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_15855	COG2986	histidine ammonia-lyase
KZA74_15865	COG1216	Glycosyl transferase, family 2
KZA74_15870	COG0318	PFAM AMP-dependent synthetase and ligase
KZA74_15880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZA74_15925	COG1426	Protein conserved in bacteria
KZA74_15960	COG0793	Belongs to the peptidase S41A family
KZA74_15975	COG2267	carboxylic ester hydrolase activity
KZA74_15985	COG1012	belongs to the aldehyde dehydrogenase family
KZA74_15990	COG3265	gluconokinase activity
KZA74_16000	COG0800	Aldolase
KZA74_16010	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KZA74_16015	COG0857	belongs to the CobB CobQ family
KZA74_16015	COG0280	phosphate acetyltransferase
KZA74_16020	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KZA74_16020	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KZA74_16040	COG0740	serine-type endopeptidase activity
KZA74_16050	COG4774	siderophore transport
KZA74_16060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KZA74_16070	COG2813	Specifically methylates the guanine in position
KZA74_16070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KZA74_16170	COG0788	formyltetrahydrofolate deformylase activity
KZA74_16195	COG4651	solute:proton antiporter activity
KZA74_16195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KZA74_16215	COG0724	RNA recognition motif
KZA74_16220	COG0210	DNA helicase
KZA74_16245	COG1733	regulation of RNA biosynthetic process
KZA74_16255	COG2900	Belongs to the SlyX family
KZA74_16260	COG0488	(ABC) transporter
KZA74_16265	COG1280	lysine exporter protein (LysE YggA)
KZA74_16270	COG1560	Kdo2-lipid A biosynthetic process
KZA74_16280	COG1301	dicarboxylic acid transport
KZA74_16335	COG0473	3-isopropylmalate dehydrogenase activity
KZA74_16390	COG0583	DNA-binding transcription factor activity
KZA74_16400	COG0625	glutathione transferase activity
KZA74_16405	COG2378	regulation of single-species biofilm formation
KZA74_16410	COG0546	phosphoglycolate phosphatase activity
KZA74_16420	COG1530	ribonuclease E activity
KZA74_16425	COG0318	PFAM AMP-dependent synthetase and ligase
KZA74_16440	COG0583	DNA-binding transcription factor activity
KZA74_16445	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_16450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KZA74_16460	COG0534	Mate efflux family protein
KZA74_16475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KZA74_16500	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KZA74_16500	COG0493	'glutamate synthase
KZA74_16510	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KZA74_16515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZA74_16530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KZA74_16540	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KZA74_16540	COG0644	oxidoreductase
KZA74_16550	COG0425	Belongs to the sulfur carrier protein TusA family
KZA74_16555	COG4535	Mg2 and Co2 transporter CorC
KZA74_16565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZA74_16585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KZA74_16590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KZA74_16590	COG0475	glutathione-regulated potassium exporter activity
KZA74_16605	COG0484	heat shock protein binding
KZA74_16610	COG0789	Transcriptional regulator
KZA74_16615	COG0598	Magnesium transport protein CorA
KZA74_16630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KZA74_16635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KZA74_16640	COG1074	ATP-dependent DNA helicase activity
KZA74_16645	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KZA74_16665	COG2226	methyltransferase
KZA74_16685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KZA74_16700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KZA74_16700	COG2111	Na H antiporter
KZA74_16705	COG1006	Multisubunit Na H antiporter MnhC subunit
KZA74_16710	COG0651	ATP synthesis coupled electron transport
KZA74_16715	COG1863	multisubunit Na H antiporter MnhE subunit
KZA74_16720	COG2212	antiporter activity
KZA74_16725	COG1320	monovalent cation:proton antiporter activity
KZA74_16740	COG0195	Participates in both transcription termination and antitermination
KZA74_16790	COG0237	dephospho-CoA kinase activity
KZA74_16800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KZA74_16815	COG0497	DNA recombination
KZA74_16825	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KZA74_16855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KZA74_16855	COG2169	Transcriptional regulator
KZA74_16860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KZA74_16925	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KZA74_16940	COG0326	Molecular chaperone. Has ATPase activity
KZA74_16955	COG2056	Na+-H+ antiporter family
KZA74_16960	COG0596	Alpha beta hydrolase
KZA74_17055	COG0546	phosphoglycolate phosphatase activity
KZA74_17060	COG1716	ATPase activity
KZA74_17105	COG0181	hydroxymethylbilane synthase activity
KZA74_17115	COG3275	phosphorelay sensor kinase activity
KZA74_17135	COG1538	Outer membrane efflux protein
KZA74_17140	COG0697	spore germination
KZA74_17165	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KZA74_17170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KZA74_17175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KZA74_17180	COG0772	Belongs to the SEDS family
KZA74_17205	COG4974	Belongs to the 'phage' integrase family
KZA74_17210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KZA74_17220	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KZA74_17230	COG2197	response regulator
KZA74_17245	COG0793	Belongs to the peptidase S41A family
KZA74_17250	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KZA74_17255	COG0795	lipopolysaccharide-transporting ATPase activity
KZA74_17295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KZA74_17295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KZA74_17305	COG0004	ammonium transporteR
KZA74_17310	COG0347	Belongs to the P(II) protein family
KZA74_17320	COG0606	chelatase, subunit chli
KZA74_17330	COG0659	secondary active sulfate transmembrane transporter activity
KZA74_17335	COG0589	response to stress
KZA74_17385	COG0606	chelatase, subunit chli
KZA74_17390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZA74_17400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KZA74_17415	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KZA74_17430	COG0318	PFAM AMP-dependent synthetase and ligase
KZA74_17440	COG0477	Major facilitator Superfamily
KZA74_17445	COG2860	membrane
KZA74_17450	COG3012	SEC-C Motif Domain Protein
KZA74_17455	COG1253	flavin adenine dinucleotide binding
KZA74_17465	COG0477	Major facilitator Superfamily
KZA74_17475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KZA74_17510	COG0655	NAD(P)H dehydrogenase (quinone) activity
KZA74_17520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KZA74_17555	COG1309	transcriptional regulator
KZA74_17590	COG0758	DNA mediated transformation
KZA74_17600	COG0697	spore germination
KZA74_17605	COG1309	transcriptional regulator
KZA74_17620	COG0386	Belongs to the glutathione peroxidase family
KZA74_17690	COG1121	(ABC) transporter
KZA74_17695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KZA74_17700	COG1280	lysine exporter protein (LysE YggA)
KZA74_17705	COG2837	iron assimilation
KZA74_17710	COG0281	malic enzyme
KZA74_17755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KZA74_17755	COG0519	Catalyzes the synthesis of GMP from XMP
KZA74_17760	COG4399	Belongs to the UPF0754 family
KZA74_17765	COG2259	Doxx family
KZA74_17770	COG0586	Pfam SNARE associated Golgi protein
KZA74_17785	COG1192	Involved in chromosome partitioning
KZA74_17795	COG0271	Belongs to the BolA IbaG family
KZA74_17835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZA74_17835	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KZA74_17835	COG3321	synthase
KZA74_17835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KZA74_17840	COG1960	acyl-CoA dehydrogenase activity
KZA74_17845	COG0318	PFAM AMP-dependent synthetase and ligase
KZA74_17850	COG2197	response regulator
KZA74_17860	COG3916	Acyl-homoserine-lactone synthase
KZA74_17865	COG0477	Major facilitator Superfamily
KZA74_17870	COG1024	Enoyl-CoA hydratase
KZA74_17875	COG1024	Enoyl-CoA hydratase
KZA74_17880	COG1960	acyl-CoA dehydrogenase activity
KZA74_17885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZA74_17905	COG1113	amino acid transport
KZA74_17910	COG1113	amino acid transport
KZA74_17915	COG0251	oxidation-reduction process
KZA74_17955	COG0564	pseudouridine synthase activity
KZA74_18035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KZA74_18050	COG1802	Transcriptional regulator
KZA74_18060	COG1448	Aminotransferase
KZA74_18065	COG0277	FAD linked oxidase domain protein
KZA74_18075	COG2186	Transcriptional regulator
KZA74_18085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KZA74_18090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KZA74_18105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KZA74_18110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KZA74_18135	COG0438	transferase activity, transferring glycosyl groups
KZA74_18165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KZA74_18195	COG0728	peptidoglycan biosynthetic process
KZA74_18200	COG3023	N-Acetylmuramoyl-L-alanine amidase
KZA74_18260	COG0546	phosphoglycolate phosphatase activity
KZA74_18265	COG1028	Short-chain dehydrogenase reductase Sdr
KZA74_18285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZA74_18290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZA74_18295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZA74_18300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZA74_18305	COG1116	anion transmembrane transporter activity
KZA74_18310	COG1309	transcriptional regulator
KZA74_18315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KZA74_18325	COG0196	riboflavin kinase activity
KZA74_18330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KZA74_18340	COG1047	Peptidyl-prolyl cis-trans
KZA74_18380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KZA74_18385	COG0657	acetylesterase activity
KZA74_18435	COG2951	lytic endotransglycosylase activity
KZA74_18440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KZA74_18455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KZA74_18465	COG0671	phosphoesterase, PA-phosphatase related
KZA74_18470	COG0861	Integral membrane protein TerC family
KZA74_18480	COG0754	glutathionylspermidine amidase activity
KZA74_18490	COG0402	S-adenosylhomocysteine deaminase activity
KZA74_18505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KZA74_18510	COG1230	cation diffusion facilitator family transporter
KZA74_18525	COG0706	membrane insertase activity
KZA74_18555	COG4691	Plasmid stability protein
KZA74_18590	COG0798	PFAM Bile acid sodium symporter
KZA74_18670	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KZA74_18700	COG0659	secondary active sulfate transmembrane transporter activity
KZA74_18705	COG0589	response to stress
KZA74_18765	COG0501	Belongs to the peptidase M48B family
KZA74_18945	COG0739	heme binding
KZA74_18975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KZA74_18990	COG1192	Involved in chromosome partitioning
KZA74_19040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KZA74_19160	COG1525	nuclease
KZA74_19230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KZA74_19255	COG0640	Transcriptional regulator
KZA74_19345	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
KZA74_19380	COG0583	DNA-binding transcription factor activity
KZA74_19405	COG3077	Addiction module antitoxin, RelB DinJ family
KZA74_19420	COG1028	Short-chain dehydrogenase reductase Sdr