locus-tag	class	description
H1I70_00010	COG0592	DNA-directed DNA polymerase activity
H1I70_00020	COG0187	DNA topoisomerase II activity
H1I70_00030	COG0586	Pfam SNARE associated Golgi protein
H1I70_00035	COG0488	(ABC) transporter
H1I70_00060	COG0596	Alpha beta hydrolase
H1I70_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1I70_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1I70_00110	COG0733	neurotransmitter:sodium symporter activity
H1I70_00150	COG2233	PERMEase
H1I70_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I70_00200	COG2814	Major facilitator Superfamily
H1I70_00205	COG0656	L-ascorbic acid biosynthetic process
H1I70_00210	COG0583	DNA-binding transcription factor activity
H1I70_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I70_00230	COG1064	alcohol dehydrogenase
H1I70_00235	COG2818	Glycosylase
H1I70_00250	COG1194	a g-specific adenine glycosylase
H1I70_00270	COG2983	Belongs to the UPF0260 family
H1I70_00275	COG2133	pyrroloquinoline quinone binding
H1I70_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1I70_00285	COG2116	formate transmembrane transporter activity
H1I70_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I70_00310	COG1335	isochorismatase
H1I70_00315	COG0385	Bile acid
H1I70_00320	COG0534	Mate efflux family protein
H1I70_00325	COG1683	Conserved Protein
H1I70_00345	COG0625	glutathione transferase activity
H1I70_00355	COG1113	amino acid transport
H1I70_00365	COG0523	cobalamin synthesis protein
H1I70_00375	COG2188	Transcriptional regulator
H1I70_00405	COG0010	Belongs to the arginase family
H1I70_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I70_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1I70_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1I70_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1I70_00540	COG0534	Mate efflux family protein
H1I70_00545	COG0436	Aminotransferase
H1I70_00550	COG2733	membrane
H1I70_00565	COG2918	glutathione biosynthetic process
H1I70_00580	COG0791	NLP P60 protein
H1I70_00580	COG1388	LysM domain
H1I70_00595	COG3150	esterase
H1I70_00605	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H1I70_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I70_00630	COG2233	PERMEase
H1I70_00635	COG2351	hydroxyisourate hydrolase activity
H1I70_00670	COG3706	GGDEF domain
H1I70_00685	COG1393	Belongs to the ArsC family
H1I70_00690	COG0708	Exodeoxyribonuclease III
H1I70_00710	COG0189	ligase activity
H1I70_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1I70_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1I70_00755	COG4942	peptidase
H1I70_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I70_00775	COG2119	membrane
H1I70_00780	COG4774	siderophore transport
H1I70_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I70_00785	COG0426	domain, Protein
H1I70_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1I70_00830	COG1902	pentaerythritol trinitrate reductase activity
H1I70_00835	COG1519	Transferase
H1I70_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I70_00845	COG0668	transmembrane transport
H1I70_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I70_00860	COG1335	isochorismatase
H1I70_00865	COG1522	sequence-specific DNA binding
H1I70_00870	COG3328	transposase activity
H1I70_00895	COG0784	Response regulator, receiver
H1I70_00895	COG2198	Histidine kinase
H1I70_00895	COG2205	protein histidine kinase activity
H1I70_00900	COG3162	membrane
H1I70_00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I70_00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I70_00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1I70_00940	COG1309	transcriptional regulator
H1I70_00965	COG0351	phosphomethylpyrimidine kinase
H1I70_00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I70_00965	COG0352	thiamine-phosphate diphosphorylase activity
H1I70_00975	COG2814	Major facilitator Superfamily
H1I70_00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I70_01000	COG1113	amino acid transport
H1I70_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I70_01015	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_01025	COG1335	isochorismatase
H1I70_01055	COG2814	Major facilitator Superfamily
H1I70_01060	COG0583	DNA-binding transcription factor activity
H1I70_01080	COG0667	Aldo Keto reductase
H1I70_01110	COG1733	regulation of RNA biosynthetic process
H1I70_01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I70_01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1I70_01200	COG2329	Antibiotic biosynthesis monooxygenase
H1I70_01230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1I70_01260	COG0427	acetyl-CoA hydrolase
H1I70_01285	COG0659	secondary active sulfate transmembrane transporter activity
H1I70_01290	COG4221	oxidoreductase activity
H1I70_01295	COG2873	o-acetylhomoserine
H1I70_01300	COG0488	(ABC) transporter
H1I70_01385	COG0833	amino acid
H1I70_01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1I70_01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1I70_01450	COG2226	methyltransferase
H1I70_01500	COG0069	glutamate synthase activity
H1I70_01500	COG0070	glutamate synthase
H1I70_01500	COG0067	glutamate synthase
H1I70_01505	COG0493	'glutamate synthase
H1I70_01515	COG1704	LemA family
H1I70_01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1I70_01540	COG3307	-O-antigen
H1I70_01565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I70_01580	COG0194	GDP metabolic process
H1I70_01630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1I70_01650	COG5380	lipid catabolic process
H1I70_01655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1I70_01680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1I70_01685	COG0277	FAD linked oxidase domain protein
H1I70_01695	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1I70_01700	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I70_01715	COG1289	transmembrane transporter activity
H1I70_01725	COG0628	permease
H1I70_01730	COG1192	Involved in chromosome partitioning
H1I70_01760	COG0833	amino acid
H1I70_01765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I70_01770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I70_01780	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_01820	COG0583	DNA-binding transcription factor activity
H1I70_01865	COG0517	IMP dehydrogenase activity
H1I70_01870	COG1983	PspC domain protein
H1I70_01880	COG1960	acyl-CoA dehydrogenase activity
H1I70_01895	COG0408	coproporphyrinogen oxidase activity
H1I70_01915	COG0513	Belongs to the DEAD box helicase family
H1I70_01925	COG1127	ABC transporter
H1I70_01930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1I70_01940	COG2854	intermembrane phospholipid transfer
H1I70_01950	COG0598	Magnesium transport protein CorA
H1I70_01960	COG0494	nUDIX hydrolase
H1I70_01965	COG1040	competence protein
H1I70_01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1I70_01990	COG1946	Acyl-CoA thioesterase
H1I70_01995	COG1301	dicarboxylic acid transport
H1I70_02010	COG1959	2 iron, 2 sulfur cluster binding
H1I70_02015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I70_02015	COG1017	nitric oxide dioxygenase activity
H1I70_02020	COG0433	COG0433 Predicted ATPase
H1I70_02025	COG0626	cystathionine gamma-synthase activity
H1I70_02180	COG1960	acyl-CoA dehydrogenase activity
H1I70_02185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1I70_02215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1I70_02220	COG0339	signal peptide processing
H1I70_02225	COG0557	exoribonuclease II activity
H1I70_02270	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1I70_02275	COG2169	Transcriptional regulator
H1I70_02280	COG0697	spore germination
H1I70_02285	COG1295	ribonuclease BN
H1I70_02320	COG1702	phosphate starvation-inducible protein PhoH
H1I70_02330	COG0739	heme binding
H1I70_02330	COG1196	nuclear chromosome segregation
H1I70_02330	COG0741	lytic transglycosylase activity
H1I70_02360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1I70_02365	COG1183	phosphatidylcholine synthase activity
H1I70_02410	COG1960	acyl-CoA dehydrogenase activity
H1I70_02415	COG1309	transcriptional regulator
H1I70_02430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I70_02435	COG1960	acyl-CoA dehydrogenase activity
H1I70_02455	COG2969	positive regulation of protein catabolic process
H1I70_02465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1I70_02480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1I70_02485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1I70_02505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1I70_02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I70_02520	COG1408	metallophosphoesterase
H1I70_02530	COG2199	diguanylate cyclase activity
H1I70_02590	COG1607	acyl-coa hydrolase
H1I70_02620	COG2350	Protein conserved in bacteria
H1I70_02630	COG0613	PHP domain protein
H1I70_02635	COG3781	membrane
H1I70_02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1I70_02650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1I70_02660	COG1862	Preprotein translocase
H1I70_02690	COG2205	protein histidine kinase activity
H1I70_02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H1I70_02715	COG0726	polysaccharide deacetylase
H1I70_02720	COG0463	Glycosyl transferase, family 2
H1I70_02725	COG0438	transferase activity, transferring glycosyl groups
H1I70_02790	COG0625	glutathione transferase activity
H1I70_02795	COG0583	DNA-binding transcription factor activity
H1I70_02800	COG1960	acyl-CoA dehydrogenase activity
H1I70_02805	COG1960	acyl-CoA dehydrogenase activity
H1I70_02815	COG2205	protein histidine kinase activity
H1I70_02820	COG0745	RESPONSE REGULATOR receiver
H1I70_02825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H1I70_02845	COG2096	Adenosyltransferase
H1I70_02895	COG0285	dihydrofolate synthase activity
H1I70_02915	COG0450	alkyl hydroperoxide reductase
H1I70_02930	COG0477	Major facilitator Superfamily
H1I70_02935	COG1272	protein, Hemolysin III
H1I70_02965	COG0183	Belongs to the thiolase family
H1I70_02970	COG2207	Transcriptional regulator
H1I70_02990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I70_03010	COG0183	Belongs to the thiolase family
H1I70_03020	COG2885	chlorophyll binding
H1I70_03020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1I70_03030	COG1690	Belongs to the RtcB family
H1I70_03035	COG0833	amino acid
H1I70_03045	COG2233	PERMEase
H1I70_03050	COG1217	gtp-binding protein TYPA
H1I70_03075	COG2094	Belongs to the DNA glycosylase MPG family
H1I70_03080	COG4772	TonB-dependent receptor
H1I70_03095	COG1902	pentaerythritol trinitrate reductase activity
H1I70_03110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I70_03115	COG0354	folic acid binding
H1I70_03125	COG3189	MarR family transcriptional regulator
H1I70_03130	COG2824	Alkylphosphonate utilization operon protein PhnA
H1I70_03135	COG3422	double-strand break repair
H1I70_03175	COG0840	transmembrane signaling receptor activity
H1I70_03195	COG5510	response to toxic substance
H1I70_03205	COG2832	Protein of unknown function (DUF454)
H1I70_03210	COG1376	ErfK ybiS ycfS ynhG family protein
H1I70_03250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1I70_03260	COG1289	transmembrane transporter activity
H1I70_03265	COG2814	Major facilitator Superfamily
H1I70_03285	COG1115	amino acid carrier protein
H1I70_03290	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I70_03295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I70_03300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1I70_03330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I70_03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I70_03345	COG1077	Cell shape determining protein MreB Mrl
H1I70_03350	COG1792	Involved in formation and maintenance of cell shape
H1I70_03355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1I70_03360	COG0424	maF-like protein
H1I70_03365	COG1530	ribonuclease E activity
H1I70_03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I70_03385	COG0560	Phosphoserine phosphatase
H1I70_03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I70_03420	COG2207	Transcriptional regulator
H1I70_03440	COG1113	amino acid transport
H1I70_03445	COG2828	Protein conserved in bacteria
H1I70_03450	COG0142	geranyltranstransferase activity
H1I70_03455	COG2315	Protein conserved in bacteria
H1I70_03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I70_03490	COG2194	sulfuric ester hydrolase activity
H1I70_03495	COG0745	RESPONSE REGULATOR receiver
H1I70_03500	COG0642	Histidine kinase
H1I70_03510	COG0004	ammonium transporteR
H1I70_03515	COG0583	DNA-binding transcription factor activity
H1I70_03535	COG0525	valine-tRNA ligase activity
H1I70_03545	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_03555	COG0393	Putative heavy-metal-binding
H1I70_03560	COG0393	Putative heavy-metal-binding
H1I70_03565	COG1538	Outer membrane efflux protein
H1I70_03575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I70_03580	COG0671	phosphoesterase, PA-phosphatase related
H1I70_03610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1I70_03625	COG1648	precorrin-2 dehydrogenase activity
H1I70_03625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1I70_03630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1I70_03635	COG1733	regulation of RNA biosynthetic process
H1I70_03645	COG0531	amino acid
H1I70_03660	COG0321	lipoyl(octanoyl) transferase activity
H1I70_03665	COG2921	Belongs to the UPF0250 family
H1I70_03705	COG2009	succinate dehydrogenase
H1I70_03710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1I70_03715	COG1053	succinate dehydrogenase
H1I70_03720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1I70_03745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I70_03765	COG2354	Protein conserved in bacteria
H1I70_03770	COG2321	neutral zinc metallopeptidase
H1I70_03810	COG2843	Capsule synthesis protein
H1I70_03825	COG0589	response to stress
H1I70_03845	COG0505	Belongs to the CarA family
H1I70_03870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I70_03875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1I70_03925	COG0477	Major facilitator Superfamily
H1I70_03930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1I70_03945	COG1597	lipid kinase activity
H1I70_03950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I70_03980	COG0584	glycerophosphoryl diester phosphodiesterase
H1I70_04000	COG0741	lytic transglycosylase activity
H1I70_04020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1I70_04035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I70_04060	COG0778	Nitroreductase
H1I70_04075	COG1929	Belongs to the glycerate kinase type-1 family
H1I70_04080	COG0243	molybdopterin cofactor binding
H1I70_04085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1I70_04090	COG3339	Conserved Protein
H1I70_04100	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H1I70_04115	COG1113	amino acid transport
H1I70_04125	COG0019	diaminopimelate decarboxylase activity
H1I70_04135	COG1280	lysine exporter protein (LysE YggA)
H1I70_04140	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I70_04170	COG0463	Glycosyl transferase, family 2
H1I70_04190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I70_04225	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1I70_04230	COG1136	(ABC) transporter
H1I70_04235	COG0658	competence protein
H1I70_04235	COG2333	competence protein COMEC
H1I70_04245	COG0616	signal peptide processing
H1I70_04245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1I70_04250	COG0596	Alpha beta hydrolase
H1I70_04255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1I70_04265	COG0628	permease
H1I70_04300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I70_04320	COG0823	Involved in the tonB-independent uptake of proteins
H1I70_04340	COG0824	Thioesterase
H1I70_04345	COG1473	amidohydrolase
H1I70_04365	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1I70_04365	COG0047	phosphoribosylformylglycinamidine synthase activity
H1I70_04370	COG2814	Major facilitator Superfamily
H1I70_04380	COG1024	Enoyl-CoA hydratase
H1I70_04385	COG1051	belongs to the nudix hydrolase family
H1I70_04385	COG1056	cytidyltransferase-related domain
H1I70_04395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1I70_04410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1I70_04425	COG4625	pathogenesis
H1I70_04430	COG0583	DNA-binding transcription factor activity
H1I70_04435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1I70_04440	COG4208	sulfate ABC transporter
H1I70_04445	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1I70_04455	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1I70_04460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1I70_04465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1I70_04485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I70_04500	COG0681	Belongs to the peptidase S26 family
H1I70_04515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1I70_04525	COG1381	Involved in DNA repair and RecF pathway recombination
H1I70_04530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1I70_04540	COG4221	oxidoreductase activity
H1I70_04570	COG0436	Aminotransferase
H1I70_04590	COG0556	nucleotide-excision repair
H1I70_04645	COG2070	2-Nitropropane dioxygenase
H1I70_04675	COG1215	transferase activity, transferring glycosyl groups
H1I70_04690	COG0415	Belongs to the DNA photolyase family
H1I70_04700	COG1252	NADH dehydrogenase
H1I70_04705	COG1686	Belongs to the peptidase S11 family
H1I70_04720	COG1187	pseudouridine synthase activity
H1I70_04745	COG0477	Major facilitator Superfamily
H1I70_04750	COG0583	DNA-binding transcription factor activity
H1I70_04755	COG1823	symporter activity
H1I70_04765	COG0612	Peptidase, M16
H1I70_04790	COG0352	thiamine-phosphate diphosphorylase activity
H1I70_04825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I70_04840	COG1309	transcriptional regulator
H1I70_04850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I70_04855	COG0076	glutamate decarboxylase activity
H1I70_04865	COG1522	sequence-specific DNA binding
H1I70_04870	COG3961	Belongs to the TPP enzyme family
H1I70_04875	COG1113	amino acid transport
H1I70_04880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I70_04885	COG0573	inorganic phosphate transmembrane transporter activity
H1I70_04895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1I70_04900	COG0616	signal peptide processing
H1I70_04935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1I70_04940	COG1686	Belongs to the peptidase S11 family
H1I70_04965	COG0583	DNA-binding transcription factor activity
H1I70_04970	COG1067	ATP-dependent peptidase activity
H1I70_05015	COG1966	Carbon starvation protein
H1I70_05020	COG2879	small protein
H1I70_05050	COG2508	Transcriptional regulator
H1I70_05050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1I70_05070	COG1113	amino acid transport
H1I70_05075	COG0583	DNA-binding transcription factor activity
H1I70_05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I70_05105	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_05110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I70_05115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I70_05115	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H1I70_05150	COG2814	Major facilitator Superfamily
H1I70_05155	COG4948	Mandelate Racemase Muconate Lactonizing
H1I70_05165	COG1309	transcriptional regulator
H1I70_05185	COG1741	Belongs to the pirin family
H1I70_05195	COG2964	Protein conserved in bacteria
H1I70_05210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I70_05215	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I70_05220	COG4605	iron ion homeostasis
H1I70_05225	COG4604	ABC transporter, ATP-binding protein
H1I70_05230	COG4607	ABC-type enterochelin transport system periplasmic component
H1I70_05235	COG4774	siderophore transport
H1I70_05245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I70_05250	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1I70_05255	COG1535	isochorismatase
H1I70_05255	COG3433	isochorismatase activity
H1I70_05270	COG1132	(ABC) transporter
H1I70_05275	COG1132	(ABC) transporter
H1I70_05280	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H1I70_05290	COG1169	isochorismate synthase
H1I70_05305	COG3739	integral membrane protein
H1I70_05330	COG0302	gtp cyclohydrolase
H1I70_05340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1I70_05370	COG0308	aminopeptidase N
H1I70_05375	COG0512	Glutamine amidotransferase of anthranilate synthase
H1I70_05390	COG0174	glutamine synthetase
H1I70_05400	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H1I70_05435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1I70_05440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1I70_05445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I70_05465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I70_05470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1I70_05475	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1I70_05490	COG1960	acyl-CoA dehydrogenase activity
H1I70_05495	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I70_05500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I70_05510	COG2223	nitrite transmembrane transporter activity
H1I70_05520	COG0024	Methionine aminopeptidase
H1I70_05525	COG0052	Belongs to the universal ribosomal protein uS2 family
H1I70_05540	COG2207	Transcriptional regulator
H1I70_05565	COG2951	lytic endotransglycosylase activity
H1I70_05570	COG0772	Belongs to the SEDS family
H1I70_05585	COG0842	Transport permease protein
H1I70_05590	COG1131	(ABC) transporter
H1I70_05635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I70_05650	COG4215	(ABC) transporter
H1I70_05655	COG4160	amino acid transport
H1I70_05660	COG4598	ABC transporter
H1I70_05670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I70_05675	COG0826	peptidase U32
H1I70_05680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I70_05695	COG1720	tRNA m6t6A37 methyltransferase activity
H1I70_05705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1I70_05720	COG0642	Histidine kinase
H1I70_05730	COG0494	nUDIX hydrolase
H1I70_05740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1I70_05745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1I70_05750	COG3139	Protein of unknown function (DUF1315)
H1I70_05755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1I70_05760	COG1301	dicarboxylic acid transport
H1I70_05765	COG1960	acyl-CoA dehydrogenase activity
H1I70_05770	COG2819	hydrolase of the alpha beta superfamily
H1I70_05780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1I70_05790	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1I70_05795	COG1234	tRNA 3'-trailer cleavage
H1I70_05825	COG2363	Small membrane protein
H1I70_05845	COG0513	Belongs to the DEAD box helicase family
H1I70_05855	COG0778	Nitroreductase
H1I70_06200	COG1286	toxin biosynthetic process
H1I70_06225	COG4783	chaperone-mediated protein folding
H1I70_06230	COG1610	YqeY-like protein
H1I70_06330	COG3111	PFAM Bacterial OB fold (BOF) protein
H1I70_06355	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1I70_06360	COG0786	glutamate:sodium symporter activity
H1I70_06370	COG2186	Transcriptional regulator
H1I70_06420	COG0477	Major facilitator Superfamily
H1I70_06525	COG0482	sulfurtransferase activity
H1I70_06540	COG0488	(ABC) transporter
H1I70_06545	COG3173	Aminoglycoside phosphotransferase
H1I70_06555	COG2433	Pfam Transposase IS66
H1I70_06590	COG1024	Enoyl-CoA hydratase
H1I70_06595	COG1024	Enoyl-CoA hydratase
H1I70_06600	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I70_06605	COG0183	Belongs to the thiolase family
H1I70_06610	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H1I70_06615	COG3327	negative regulation of DNA-templated transcription, initiation
H1I70_06625	COG2050	protein possibly involved in aromatic compounds catabolism
H1I70_06660	COG0753	catalase activity
H1I70_06665	COG3038	cytochrome b561
H1I70_06685	COG2267	carboxylic ester hydrolase activity
H1I70_06690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I70_06695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I70_06700	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_06710	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I70_06720	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_06725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I70_06730	COG0583	DNA-binding transcription factor activity
H1I70_06740	COG1414	Transcriptional regulator
H1I70_06745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I70_06755	COG1840	ABC-type Fe3 transport system, periplasmic component
H1I70_06760	COG3842	ATPase activity
H1I70_06775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H1I70_06780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I70_06785	COG2814	Major facilitator Superfamily
H1I70_06790	COG1960	acyl-CoA dehydrogenase activity
H1I70_06805	COG1024	Enoyl-CoA hydratase
H1I70_06815	COG2814	Major facilitator Superfamily
H1I70_06825	COG0183	Belongs to the thiolase family
H1I70_06830	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I70_06835	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_06840	COG1024	Enoyl-CoA hydratase
H1I70_06845	COG1960	acyl-CoA dehydrogenase activity
H1I70_06850	COG2814	Major facilitator Superfamily
H1I70_06855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I70_06860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I70_06870	COG2814	Major facilitator Superfamily
H1I70_06880	COG1960	acyl-CoA dehydrogenase activity
H1I70_06895	COG0583	DNA-binding transcription factor activity
H1I70_06905	COG4770	biotin carboxylase activity
H1I70_06910	COG1024	Enoyl-CoA hydratase
H1I70_06915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I70_06920	COG1960	acyl-CoA dehydrogenase activity
H1I70_06925	COG1309	transcriptional regulator
H1I70_06930	COG0318	PFAM AMP-dependent synthetase and ligase
H1I70_06950	COG0583	DNA-binding transcription factor activity
H1I70_07000	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_07020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I70_07040	COG0784	Response regulator, receiver
H1I70_07040	COG2205	protein histidine kinase activity
H1I70_07060	COG0765	amino acid transport
H1I70_07065	COG0765	amino acid transport
H1I70_07070	COG1126	abc transporter atp-binding protein
H1I70_07075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I70_07080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I70_07095	COG1280	lysine exporter protein (LysE YggA)
H1I70_07105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1I70_07110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I70_07115	COG1045	serine acetyltransferase
H1I70_07130	COG0583	DNA-binding transcription factor activity
H1I70_07135	COG0625	glutathione transferase activity
H1I70_07140	COG0625	glutathione transferase activity
H1I70_07145	COG0583	DNA-binding transcription factor activity
H1I70_07155	COG1346	cytolysis
H1I70_07175	COG2814	Major facilitator Superfamily
H1I70_07185	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H1I70_07190	COG3052	prosthetic group binding
H1I70_07210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1I70_07230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I70_07240	COG1294	oxidase, subunit
H1I70_07245	COG1271	oxidase subunit
H1I70_07265	COG0477	Major facilitator Superfamily
H1I70_07275	COG4521	taurine ABC transporter
H1I70_07280	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1I70_07285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I70_07290	COG2175	clavaminate synthase activity
H1I70_07300	COG1953	Uracil, thiamine, allantoin
H1I70_07310	COG0583	DNA-binding transcription factor activity
H1I70_07320	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1I70_07335	COG0640	Transcriptional regulator
H1I70_07340	COG0798	PFAM Bile acid sodium symporter
H1I70_07345	COG0583	DNA-binding transcription factor activity
H1I70_07360	COG3634	alkyl hydroperoxide reductase activity
H1I70_07400	COG0436	Aminotransferase
H1I70_07410	COG0386	Belongs to the glutathione peroxidase family
H1I70_07450	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I70_07475	COG0012	GTP binding
H1I70_07480	COG2011	ABC-type metal ion transport system permease component
H1I70_07485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I70_07505	COG1464	Belongs to the NlpA lipoprotein family
H1I70_07535	COG0765	amino acid transport
H1I70_07540	COG0765	amino acid transport
H1I70_07545	COG1126	abc transporter atp-binding protein
H1I70_07560	COG1522	sequence-specific DNA binding
H1I70_07575	COG1309	transcriptional regulator
H1I70_07595	COG0583	DNA-binding transcription factor activity
H1I70_07605	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I70_07615	COG0697	spore germination
H1I70_07640	COG3121	Chaperone
H1I70_07645	COG3539	Fimbrial protein
H1I70_07670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1I70_07670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1I70_07715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1I70_07725	COG2353	YceI-like domain
H1I70_07735	COG3698	Phosphodiester glycosidase
H1I70_07750	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H1I70_07755	COG0506	proline dehydrogenase activity
H1I70_07755	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I70_07755	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I70_07765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I70_07770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1I70_07790	COG1132	(ABC) transporter
H1I70_07795	COG3122	Protein conserved in bacteria
H1I70_07800	COG3619	membrane
H1I70_07810	COG0640	Transcriptional regulator
H1I70_07820	COG2850	peptidyl-arginine hydroxylation
H1I70_07825	COG0424	maF-like protein
H1I70_07845	COG0191	fructose-bisphosphate aldolase activity
H1I70_07850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I70_07865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1I70_07875	COG1192	Involved in chromosome partitioning
H1I70_07880	COG1475	DNA binding
H1I70_07885	COG0811	peptide transport
H1I70_07895	COG1132	(ABC) transporter
H1I70_07900	COG1663	tetraacyldisaccharide 4'-kinase activity
H1I70_07920	COG0084	hydrolase, TatD family'
H1I70_07985	COG0776	regulation of translation
H1I70_08015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1I70_08020	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1I70_08070	COG0339	signal peptide processing
H1I70_08080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1I70_08115	COG0702	epimerase
H1I70_08120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I70_08140	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1I70_08170	COG0316	Belongs to the HesB IscA family
H1I70_08175	COG0822	iron-sulfur transferase activity
H1I70_08200	COG0776	regulation of translation
H1I70_08205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I70_08210	COG2207	Transcriptional regulator
H1I70_08215	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I70_08220	COG1960	acyl-CoA dehydrogenase activity
H1I70_08225	COG1960	acyl-CoA dehydrogenase activity
H1I70_08240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1I70_08260	COG4264	IucA IucC family
H1I70_08265	COG4264	IucA IucC family
H1I70_08305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I70_08320	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H1I70_08340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1I70_08345	COG0730	response to heat
H1I70_08365	COG4773	Receptor
H1I70_08370	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I70_08385	COG1131	(ABC) transporter
H1I70_08390	COG0842	Transport permease protein
H1I70_08395	COG0842	Transport permease protein
H1I70_08450	COG2226	methyltransferase
H1I70_08475	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1I70_08510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I70_08520	COG0133	tryptophan synthase activity
H1I70_08535	COG3706	GGDEF domain
H1I70_08550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I70_08555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1I70_08560	COG0022	dehydrogenase e1 component
H1I70_08565	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I70_08570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I70_08580	COG1063	alcohol dehydrogenase
H1I70_08585	COG3781	membrane
H1I70_08595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I70_08595	COG3453	Protein conserved in bacteria
H1I70_08605	COG0730	response to heat
H1I70_08620	COG2207	Transcriptional regulator
H1I70_08620	COG3708	Transcriptional regulator
H1I70_08625	COG1733	regulation of RNA biosynthetic process
H1I70_08630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1I70_08640	COG2188	Transcriptional regulator
H1I70_08655	COG4521	taurine ABC transporter
H1I70_08660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I70_08680	COG0477	Major facilitator Superfamily
H1I70_08690	COG1027	Aspartate ammonia-lyase
H1I70_08705	COG0583	DNA-binding transcription factor activity
H1I70_08710	COG0583	DNA-binding transcription factor activity
H1I70_08715	COG0183	Belongs to the thiolase family
H1I70_08720	COG2031	fatty acid transporter
H1I70_08725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I70_08735	COG0583	DNA-binding transcription factor activity
H1I70_08745	COG2610	gluconate transmembrane transporter activity
H1I70_08750	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_08760	COG2207	Transcriptional regulator
H1I70_08775	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_08800	COG0543	2 iron, 2 sulfur cluster binding
H1I70_08800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I70_08805	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I70_08810	COG4638	Rieske (2fe-2S)
H1I70_08820	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1I70_08825	COG4149	molybdate abc transporter
H1I70_08830	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1I70_08835	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_08840	COG1535	isochorismatase
H1I70_08840	COG3433	isochorismatase activity
H1I70_08905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I70_08920	COG0753	catalase activity
H1I70_08930	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H1I70_08960	COG3539	Fimbrial protein
H1I70_08980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I70_09000	COG2072	flavoprotein involved in K transport
H1I70_09010	COG1538	Outer membrane efflux protein
H1I70_09015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I70_09020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I70_09025	COG0745	RESPONSE REGULATOR receiver
H1I70_09030	COG2205	protein histidine kinase activity
H1I70_09040	COG2207	Transcriptional regulator
H1I70_09055	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_09105	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H1I70_09220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I70_09240	COG1120	ATPase activity
H1I70_09245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I70_09255	COG1064	alcohol dehydrogenase
H1I70_09270	COG2207	Transcriptional regulator
H1I70_09275	COG2084	Dehydrogenase
H1I70_09285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1I70_09290	COG0583	DNA-binding transcription factor activity
H1I70_09300	COG0129	dihydroxy-acid dehydratase activity
H1I70_09305	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_09320	COG1566	PFAM secretion protein HlyD family protein
H1I70_09340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I70_09370	COG0583	DNA-binding transcription factor activity
H1I70_09385	COG2188	Transcriptional regulator
H1I70_09415	COG3210	domain, Protein
H1I70_09420	COG2831	hemolysin activation secretion protein
H1I70_09435	COG1473	amidohydrolase
H1I70_09445	COG0475	glutathione-regulated potassium exporter activity
H1I70_09445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I70_09455	COG0583	DNA-binding transcription factor activity
H1I70_09460	COG1335	isochorismatase
H1I70_09470	COG1309	transcriptional regulator
H1I70_09500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1I70_09510	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I70_09510	COG1902	pentaerythritol trinitrate reductase activity
H1I70_09515	COG1846	Transcriptional regulator
H1I70_09535	COG0753	catalase activity
H1I70_09550	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_09575	COG3162	membrane
H1I70_09585	COG3829	transcription factor binding
H1I70_09590	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_09595	COG1960	acyl-CoA dehydrogenase activity
H1I70_09615	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_09635	COG2186	Transcriptional regulator
H1I70_09645	COG0583	DNA-binding transcription factor activity
H1I70_09650	COG4948	Mandelate Racemase Muconate Lactonizing
H1I70_09655	COG4829	muconolactone delta-isomerase
H1I70_09665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I70_09670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I70_09675	COG0183	Belongs to the thiolase family
H1I70_09680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I70_09690	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_09700	COG3733	amine oxidase
H1I70_09710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I70_09720	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_09730	COG4638	Rieske (2fe-2S)
H1I70_09750	COG0154	amidase activity
H1I70_09760	COG2814	Major facilitator Superfamily
H1I70_09785	COG1960	acyl-CoA dehydrogenase activity
H1I70_09790	COG0583	DNA-binding transcription factor activity
H1I70_09795	COG1414	Transcriptional regulator
H1I70_09810	COG2391	methyltransferase activity
H1I70_09820	COG4993	Dehydrogenase
H1I70_09825	COG3659	wide pore channel activity
H1I70_09830	COG3420	alginic acid biosynthetic process
H1I70_09835	COG0710	3-dehydroquinate dehydratase activity
H1I70_09840	COG3485	protocatechuate 3,4-dioxygenase
H1I70_09845	COG3485	protocatechuate 3,4-dioxygenase
H1I70_09850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I70_09855	COG2271	Major facilitator Superfamily
H1I70_09860	COG0596	Alpha beta hydrolase
H1I70_09865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1I70_09870	COG0183	Belongs to the thiolase family
H1I70_09875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I70_09880	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I70_09890	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1I70_09895	COG2323	membrane
H1I70_09940	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I70_09940	COG1902	pentaerythritol trinitrate reductase activity
H1I70_09965	COG0542	response to heat
H1I70_09970	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1I70_10000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I70_10005	COG0569	domain protein
H1I70_10010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1I70_10025	COG4774	siderophore transport
H1I70_10030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1I70_10040	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1I70_10055	COG1294	oxidase, subunit
H1I70_10060	COG4890	Cyd operon protein YbgT
H1I70_10075	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H1I70_10085	COG0552	protein localization to endoplasmic reticulum
H1I70_10110	COG0516	GMP reductase activity
H1I70_10110	COG0517	IMP dehydrogenase activity
H1I70_10115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I70_10120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1I70_10130	COG0583	DNA-binding transcription factor activity
H1I70_10135	COG0024	Methionine aminopeptidase
H1I70_10165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1I70_10165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I70_10170	COG1105	Belongs to the carbohydrate kinase PfkB family
H1I70_10175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I70_10175	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1I70_10175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I70_10195	COG3300	MHYT domain
H1I70_10195	COG5001	Diguanylate cyclase
H1I70_10210	COG2135	peptidase activity
H1I70_10215	COG0659	secondary active sulfate transmembrane transporter activity
H1I70_10230	COG1113	amino acid transport
H1I70_10240	COG1522	sequence-specific DNA binding
H1I70_10265	COG1011	Hydrolase
H1I70_10270	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1I70_10280	COG2137	regulation of response to DNA damage stimulus
H1I70_10295	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I70_10330	COG0575	Belongs to the CDS family
H1I70_10335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1I70_10355	COG3852	Histidine kinase
H1I70_10360	COG2204	response regulator
H1I70_10425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I70_10430	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1I70_10450	COG0697	spore germination
H1I70_10455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I70_10465	COG0303	'Molybdopterin
H1I70_10470	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1I70_10470	COG0315	cyclic pyranopterin monophosphate synthase activity
H1I70_10485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1I70_10490	COG0243	molybdopterin cofactor binding
H1I70_10500	COG0243	molybdopterin cofactor binding
H1I70_10505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I70_10510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I70_10510	COG2146	nitrite reductase [NAD(P)H] activity
H1I70_10520	COG0745	RESPONSE REGULATOR receiver
H1I70_10525	COG1116	anion transmembrane transporter activity
H1I70_10525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I70_10545	COG0511	ligase activity, forming carbon-carbon bonds
H1I70_10560	COG2814	Major facilitator Superfamily
H1I70_10650	COG1598	PFAM Uncharacterised protein family UPF0150
H1I70_10760	COG5410	chromosome segregation
H1I70_10940	COG0069	glutamate synthase activity
H1I70_10960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1I70_10970	COG1454	alcohol dehydrogenase
H1I70_10975	COG0824	Thioesterase
H1I70_10985	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1I70_11000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I70_11005	COG2030	dehydratase
H1I70_11015	COG0183	Belongs to the thiolase family
H1I70_11025	COG0583	DNA-binding transcription factor activity
H1I70_11030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1I70_11040	COG1522	sequence-specific DNA binding
H1I70_11045	COG3135	benzoate transporter
H1I70_11055	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1I70_11080	COG0589	response to stress
H1I70_11085	COG0488	(ABC) transporter
H1I70_11105	COG4773	Receptor
H1I70_11140	COG0668	transmembrane transport
H1I70_11150	COG1309	transcriptional regulator
H1I70_11165	COG1605	Chorismate mutase
H1I70_11175	COG4221	oxidoreductase activity
H1I70_11185	COG0308	aminopeptidase N
H1I70_11205	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1I70_11215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I70_11220	COG1454	alcohol dehydrogenase
H1I70_11240	COG0531	amino acid
H1I70_11245	COG4303	Ethanolamine ammonia lyase large subunit
H1I70_11250	COG4302	ethanolamine ammonia-lyase activity
H1I70_11255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I70_11255	COG0519	Catalyzes the synthesis of GMP from XMP
H1I70_11260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I70_11270	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I70_11285	COG0697	spore germination
H1I70_11290	COG1923	regulation of RNA biosynthetic process
H1I70_11300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1I70_11305	COG0802	atpase or kinase
H1I70_11325	COG1187	pseudouridine synthase activity
H1I70_11340	COG0583	DNA-binding transcription factor activity
H1I70_11355	COG2814	Major facilitator Superfamily
H1I70_11360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I70_11385	COG0729	surface antigen
H1I70_11405	COG0174	glutamine synthetase
H1I70_11410	COG0745	RESPONSE REGULATOR receiver
H1I70_11415	COG2205	protein histidine kinase activity
H1I70_11425	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1I70_11430	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1I70_11455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I70_11460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I70_11465	COG1960	acyl-CoA dehydrogenase activity
H1I70_11480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I70_11485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I70_11505	COG0583	DNA-binding transcription factor activity
H1I70_11520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I70_11530	COG3658	cytochrome
H1I70_11535	COG1215	transferase activity, transferring glycosyl groups
H1I70_11540	COG1649	PFAM Uncharacterised BCR, COG1649
H1I70_11540	COG0726	polysaccharide deacetylase
H1I70_11565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1I70_11570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1I70_11580	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1I70_11605	COG0305	Participates in initiation and elongation during chromosome replication
H1I70_11610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1I70_11620	COG1305	Transglutaminase-like
H1I70_11630	COG2308	Evidence 4 Homologs of previously reported genes of
H1I70_11660	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H1I70_11665	COG0138	bifunctional purine biosynthesis protein purh
H1I70_11670	COG0151	Belongs to the GarS family
H1I70_11675	COG1464	Belongs to the NlpA lipoprotein family
H1I70_11680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I70_11685	COG2011	ABC-type metal ion transport system permease component
H1I70_11690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I70_11700	COG1301	dicarboxylic acid transport
H1I70_11725	COG2151	metal-sulfur cluster biosynthetic enzyme
H1I70_11730	COG3396	Phenylacetate-CoA oxygenase
H1I70_11735	COG3460	Phenylacetate-CoA oxygenase
H1I70_11740	COG3396	Phenylacetate-CoA oxygenase
H1I70_11745	COG2030	dehydratase
H1I70_11745	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_11750	COG1760	l-serine dehydratase
H1I70_11755	COG0531	amino acid
H1I70_11760	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_11775	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I70_11785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I70_11805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I70_11815	COG0789	Transcriptional regulator
H1I70_11830	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1I70_11845	COG2807	transmembrane transport
H1I70_11850	COG0590	tRNA wobble adenosine to inosine editing
H1I70_11965	COG1116	anion transmembrane transporter activity
H1I70_11970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I70_11980	COG0864	Transcriptional regulator
H1I70_12000	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I70_12005	COG0439	Biotin carboxylase
H1I70_12020	COG1063	alcohol dehydrogenase
H1I70_12030	COG1309	transcriptional regulator
H1I70_12050	COG0038	chloride channel
H1I70_12055	COG4770	biotin carboxylase activity
H1I70_12075	COG1914	H( )-stimulated, divalent metal cation uptake system
H1I70_12080	COG0583	DNA-binding transcription factor activity
H1I70_12130	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I70_12150	COG2814	Major facilitator Superfamily
H1I70_12160	COG1560	Kdo2-lipid A biosynthetic process
H1I70_12170	COG5006	permease, DMT superfamily
H1I70_12175	COG1522	sequence-specific DNA binding
H1I70_12190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1I70_12200	COG4122	O-methyltransferase activity
H1I70_12230	COG1538	Outer membrane efflux protein
H1I70_12235	COG1137	ATPase activity
H1I70_12240	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1I70_12250	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1I70_12255	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1I70_12255	COG0517	IMP dehydrogenase activity
H1I70_12300	COG2814	Major facilitator Superfamily
H1I70_12335	COG1278	Cold shock
H1I70_12340	COG1280	lysine exporter protein (LysE YggA)
H1I70_12370	COG1570	exodeoxyribonuclease VII activity
H1I70_12420	COG0583	DNA-binding transcription factor activity
H1I70_12425	COG4638	Rieske (2fe-2S)
H1I70_12430	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I70_12435	COG0543	2 iron, 2 sulfur cluster binding
H1I70_12435	COG0633	Ferredoxin
H1I70_12440	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_12445	COG3135	benzoate transporter
H1I70_12450	COG2814	Major facilitator Superfamily
H1I70_12465	COG1643	Atp-dependent helicase
H1I70_12470	COG0450	alkyl hydroperoxide reductase
H1I70_12480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1I70_12490	COG3634	alkyl hydroperoxide reductase activity
H1I70_12510	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1I70_12515	COG0625	glutathione transferase activity
H1I70_12525	COG2885	chlorophyll binding
H1I70_12560	COG0542	response to heat
H1I70_12575	COG1765	OsmC-like protein
H1I70_12590	COG0667	Aldo Keto reductase
H1I70_12605	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1I70_12615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1I70_12625	COG0527	aspartate kinase activity
H1I70_12635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1I70_12645	COG3038	cytochrome b561
H1I70_12650	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1I70_12655	COG2252	PERMEase
H1I70_12665	COG2072	flavoprotein involved in K transport
H1I70_12680	COG1741	Belongs to the pirin family
H1I70_12685	COG1309	transcriptional regulator
H1I70_12695	COG0300	oxidoreductase activity
H1I70_12800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1I70_12830	COG1113	amino acid transport
H1I70_12850	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_12870	COG0531	amino acid
H1I70_12880	COG1113	amino acid transport
H1I70_12920	COG3209	COG3209 Rhs family protein
H1I70_12950	COG4269	membrane
H1I70_12965	COG1902	pentaerythritol trinitrate reductase activity
H1I70_12965	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I70_12975	COG5001	Diguanylate cyclase
H1I70_12975	COG2203	Gaf domain
H1I70_12975	COG3706	GGDEF domain
H1I70_12975	COG4251	negative regulation of phosphorylation
H1I70_12985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I70_13005	COG4172	Belongs to the ABC transporter superfamily
H1I70_13010	COG4239	(ABC) transporter, permease
H1I70_13015	COG4174	ABC transporter (Permease)
H1I70_13025	COG1388	LysM domain
H1I70_13025	COG0741	lytic transglycosylase activity
H1I70_13025	COG0741	lytic transglycosylase activity
H1I70_13025	COG1388	LysM domain
H1I70_13030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I70_13070	COG0583	DNA-binding transcription factor activity
H1I70_13075	COG1279	arginine transmembrane transporter activity
H1I70_13095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I70_13100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I70_13105	COG0006	proline dipeptidase activity
H1I70_13190	COG0739	heme binding
H1I70_13190	COG1196	nuclear chromosome segregation
H1I70_13190	COG0741	lytic transglycosylase activity
H1I70_13250	COG4695	Portal protein
H1I70_13345	COG0305	Participates in initiation and elongation during chromosome replication
H1I70_13360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I70_13410	COG2194	sulfuric ester hydrolase activity
H1I70_13455	COG0739	heme binding
H1I70_13780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1I70_13805	COG3384	dioxygenase
H1I70_13815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I70_13820	COG2878	Part of a membrane complex involved in electron transport
H1I70_13825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1I70_13850	COG0768	penicillin binding
H1I70_13855	COG0742	ribosomal rna small subunit methyltransferase
H1I70_13870	COG0830	nickel cation binding
H1I70_13880	COG0804	urea catabolic process
H1I70_13920	COG1253	flavin adenine dinucleotide binding
H1I70_13925	COG2851	Citrate transporter
H1I70_13975	COG1773	rubredoxin
H1I70_13980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I70_13990	COG0583	DNA-binding transcription factor activity
H1I70_14015	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1I70_14020	COG4181	ATPase activity
H1I70_14065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1I70_14085	COG0306	phosphate transporter
H1I70_14095	COG3958	Transketolase
H1I70_14100	COG3959	Transketolase, thiamine diphosphate binding domain
H1I70_14105	COG2271	Major facilitator Superfamily
H1I70_14110	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_14115	COG0583	DNA-binding transcription factor activity
H1I70_14130	COG2223	nitrite transmembrane transporter activity
H1I70_14135	COG2207	Transcriptional regulator
H1I70_14140	COG2066	Belongs to the glutaminase family
H1I70_14145	COG0242	peptide deformylase activity
H1I70_14150	COG0477	Major facilitator Superfamily
H1I70_14160	COG0028	Belongs to the TPP enzyme family
H1I70_14175	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_14180	COG2267	carboxylic ester hydrolase activity
H1I70_14190	COG2271	Major facilitator Superfamily
H1I70_14195	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I70_14205	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_14225	COG1414	Transcriptional regulator
H1I70_14240	COG1024	Enoyl-CoA hydratase
H1I70_14250	COG1215	transferase activity, transferring glycosyl groups
H1I70_14255	COG0726	polysaccharide deacetylase
H1I70_14255	COG1649	PFAM Uncharacterised BCR, COG1649
H1I70_14265	COG4681	YaeQ
H1I70_14275	COG0523	cobalamin synthesis protein
H1I70_14285	COG1607	acyl-coa hydrolase
H1I70_14295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I70_14300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I70_14305	COG1309	transcriptional regulator
H1I70_14330	COG2040	homocysteine
H1I70_14335	COG0531	amino acid
H1I70_14390	COG1595	DNA-templated transcription, initiation
H1I70_14400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I70_14405	COG0477	Major facilitator Superfamily
H1I70_14425	COG0084	hydrolase, TatD family'
H1I70_14460	COG0629	single-stranded DNA binding
H1I70_14515	COG0582	viral genome integration into host DNA
H1I70_14540	COG1061	Type III restriction enzyme res subunit
H1I70_14550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I70_14555	COG1192	Involved in chromosome partitioning
H1I70_14565	COG1061	Type III restriction enzyme res subunit
H1I70_14650	COG0592	DNA-directed DNA polymerase activity
H1I70_14690	COG2026	Addiction module toxin, RelE StbE family
H1I70_14840	COG3755	Protein conserved in bacteria
H1I70_14885	COG1484	DNA-dependent DNA replication
H1I70_14975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I70_15045	COG0405	Gamma-glutamyltransferase
H1I70_15050	COG2814	Major facilitator Superfamily
H1I70_15060	COG2050	protein possibly involved in aromatic compounds catabolism
H1I70_15075	COG1090	epimerase
H1I70_15095	COG0420	3'-5' exonuclease activity
H1I70_15120	COG0735	belongs to the Fur family
H1I70_15125	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1I70_15145	COG0121	glutamine amidotransferase
H1I70_15160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I70_15170	COG0210	DNA helicase
H1I70_15175	COG2885	chlorophyll binding
H1I70_15180	COG0204	Acyl-transferase
H1I70_15195	COG2894	cell division
H1I70_15215	COG1280	lysine exporter protein (LysE YggA)
H1I70_15220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1I70_15220	COG1674	ftsk spoiiie
H1I70_15225	COG0492	ferredoxin-NADP+ reductase activity
H1I70_15230	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H1I70_15240	COG0456	acetyltransferase
H1I70_15285	COG1981	membrane
H1I70_15300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1I70_15300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I70_15320	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_15330	COG0657	acetylesterase activity
H1I70_15340	COG0473	3-isopropylmalate dehydrogenase activity
H1I70_15345	COG0583	DNA-binding transcription factor activity
H1I70_15365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I70_15390	COG0564	pseudouridine synthase activity
H1I70_15400	COG0358	DNA primase activity
H1I70_15415	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H1I70_15445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I70_15475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1I70_15485	COG0352	thiamine-phosphate diphosphorylase activity
H1I70_15485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I70_15485	COG0351	phosphomethylpyrimidine kinase
H1I70_15490	COG1652	LysM domain
H1I70_15515	COG1399	metal-binding, possibly nucleic acid-binding protein
H1I70_15520	COG3101	peptidyl-lysine hydroxylation
H1I70_15525	COG0009	L-threonylcarbamoyladenylate synthase
H1I70_15530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H1I70_15535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H1I70_15550	COG4106	trans-aconitate 2-methyltransferase activity
H1I70_15565	COG0596	Alpha beta hydrolase
H1I70_15565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I70_15565	COG2226	methyltransferase
H1I70_15570	COG1877	trehalose-phosphatase activity
H1I70_15575	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1I70_15580	COG2223	nitrite transmembrane transporter activity
H1I70_15600	COG1196	nuclear chromosome segregation
H1I70_15610	COG0730	response to heat
H1I70_15625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1I70_15635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I70_15685	COG0489	protein tyrosine kinase activity
H1I70_15695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I70_15695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I70_15725	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H1I70_15730	COG2081	HI0933 family
H1I70_15740	COG0668	transmembrane transport
H1I70_15760	COG0583	DNA-binding transcription factor activity
H1I70_15780	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1I70_15785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I70_15815	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H1I70_15855	COG0745	RESPONSE REGULATOR receiver
H1I70_15875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1I70_15885	COG2205	protein histidine kinase activity
H1I70_15955	COG4993	Dehydrogenase
H1I70_15980	COG0384	phenazine biosynthesis protein PhzF
H1I70_16000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I70_16015	COG0583	DNA-binding transcription factor activity
H1I70_16045	COG0583	DNA-binding transcription factor activity
H1I70_16060	COG0583	DNA-binding transcription factor activity
H1I70_16065	COG1053	succinate dehydrogenase
H1I70_16075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1I70_16080	COG2814	Major facilitator Superfamily
H1I70_16085	COG1960	acyl-CoA dehydrogenase activity
H1I70_16090	COG0583	DNA-binding transcription factor activity
H1I70_16095	COG1063	alcohol dehydrogenase
H1I70_16125	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1I70_16130	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1I70_16135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I70_16150	COG3667	copper resistance
H1I70_16155	COG2132	Multicopper oxidase
H1I70_16165	COG0561	phosphatase activity
H1I70_16170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1I70_16195	COG1214	PFAM Peptidase M22, glycoprotease
H1I70_16245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1I70_16255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1I70_16260	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H1I70_16265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1I70_16325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I70_16335	COG1846	Transcriptional regulator
H1I70_16340	COG1764	response to oxidative stress
H1I70_16380	COG0037	tRNA processing
H1I70_16390	COG0248	Ppx GppA phosphatase
H1I70_16420	COG0072	phenylalanine-tRNA ligase activity
H1I70_16460	COG1238	metal cluster binding
H1I70_16465	COG0625	glutathione transferase activity
H1I70_16480	COG0318	PFAM AMP-dependent synthetase and ligase
H1I70_16485	COG3028	Belongs to the UPF0307 family
H1I70_16490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I70_16510	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1I70_16515	COG0617	tRNA 3'-terminal CCA addition
H1I70_16520	COG1555	photosystem II stabilization
H1I70_16525	COG3956	TIGRFAM MazG family protein
H1I70_16535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I70_16555	COG0784	Response regulator, receiver
H1I70_16555	COG2205	protein histidine kinase activity
H1I70_16555	COG5002	protein histidine kinase activity
H1I70_16560	COG1024	Enoyl-CoA hydratase
H1I70_16565	COG2084	Dehydrogenase
H1I70_16570	COG3622	Belongs to the hyi family
H1I70_16600	COG0697	spore germination
H1I70_16610	COG2814	Major facilitator Superfamily
H1I70_16615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I70_16625	COG0583	DNA-binding transcription factor activity
H1I70_16635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1I70_16650	COG0084	hydrolase, TatD family'
H1I70_16665	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1I70_16695	COG0440	acetolactate synthase activity
H1I70_16700	COG0028	Belongs to the TPP enzyme family
H1I70_16725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I70_16730	COG0577	efflux transmembrane transporter activity
H1I70_16730	COG1136	(ABC) transporter
H1I70_16735	COG1538	Outer membrane efflux protein
H1I70_16750	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H1I70_16755	COG1162	GTPase activity
H1I70_16765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1I70_16785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1I70_16790	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_16830	COG2986	histidine ammonia-lyase
H1I70_16845	COG0318	PFAM AMP-dependent synthetase and ligase
H1I70_16855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I70_16900	COG1426	Protein conserved in bacteria
H1I70_16935	COG0793	Belongs to the peptidase S41A family
H1I70_16950	COG2267	carboxylic ester hydrolase activity
H1I70_16960	COG1012	belongs to the aldehyde dehydrogenase family
H1I70_16965	COG3265	gluconokinase activity
H1I70_16975	COG0800	Aldolase
H1I70_16985	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1I70_16990	COG0280	phosphate acetyltransferase
H1I70_16990	COG0857	belongs to the CobB CobQ family
H1I70_16995	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I70_16995	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I70_17015	COG0740	serine-type endopeptidase activity
H1I70_17025	COG4774	siderophore transport
H1I70_17035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1I70_17045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I70_17045	COG2813	Specifically methylates the guanine in position
H1I70_17145	COG0788	formyltetrahydrofolate deformylase activity
H1I70_17170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I70_17170	COG4651	solute:proton antiporter activity
H1I70_17190	COG0724	RNA recognition motif
H1I70_17195	COG0210	DNA helicase
H1I70_17220	COG1733	regulation of RNA biosynthetic process
H1I70_17230	COG2900	Belongs to the SlyX family
H1I70_17235	COG0488	(ABC) transporter
H1I70_17240	COG1280	lysine exporter protein (LysE YggA)
H1I70_17245	COG1560	Kdo2-lipid A biosynthetic process
H1I70_17255	COG1301	dicarboxylic acid transport
H1I70_17310	COG0473	3-isopropylmalate dehydrogenase activity
H1I70_17375	COG0583	DNA-binding transcription factor activity
H1I70_17385	COG0625	glutathione transferase activity
H1I70_17390	COG2378	regulation of single-species biofilm formation
H1I70_17395	COG0546	phosphoglycolate phosphatase activity
H1I70_17405	COG1530	ribonuclease E activity
H1I70_17410	COG0318	PFAM AMP-dependent synthetase and ligase
H1I70_17425	COG0583	DNA-binding transcription factor activity
H1I70_17430	COG4221	oxidoreductase activity
H1I70_17435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1I70_17445	COG0534	Mate efflux family protein
H1I70_17460	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1I70_17500	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1I70_17505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I70_17520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I70_17530	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1I70_17530	COG0644	oxidoreductase
H1I70_17535	COG0425	Belongs to the sulfur carrier protein TusA family
H1I70_17540	COG4535	Mg2 and Co2 transporter CorC
H1I70_17550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I70_17570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1I70_17575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I70_17575	COG0475	glutathione-regulated potassium exporter activity
H1I70_17580	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H1I70_17590	COG0484	heat shock protein binding
H1I70_17595	COG0789	Transcriptional regulator
H1I70_17600	COG0598	Magnesium transport protein CorA
H1I70_17615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I70_17620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I70_17625	COG1074	ATP-dependent DNA helicase activity
H1I70_17630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1I70_17650	COG2226	methyltransferase
H1I70_17665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I70_17670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H1I70_17685	COG2111	Na H antiporter
H1I70_17685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I70_17690	COG1006	Multisubunit Na H antiporter MnhC subunit
H1I70_17695	COG0651	ATP synthesis coupled electron transport
H1I70_17700	COG1863	multisubunit Na H antiporter MnhE subunit
H1I70_17705	COG2212	antiporter activity
H1I70_17710	COG1320	monovalent cation:proton antiporter activity
H1I70_17725	COG0195	Participates in both transcription termination and antitermination
H1I70_17775	COG0237	dephospho-CoA kinase activity
H1I70_17785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I70_17800	COG0497	DNA recombination
H1I70_17810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1I70_17840	COG2169	Transcriptional regulator
H1I70_17840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I70_17845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1I70_17910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1I70_17925	COG0326	Molecular chaperone. Has ATPase activity
H1I70_17940	COG2056	Na+-H+ antiporter family
H1I70_17945	COG0596	Alpha beta hydrolase
H1I70_18040	COG0546	phosphoglycolate phosphatase activity
H1I70_18045	COG1716	ATPase activity
H1I70_18090	COG0181	hydroxymethylbilane synthase activity
H1I70_18100	COG3275	phosphorelay sensor kinase activity
H1I70_18120	COG1538	Outer membrane efflux protein
H1I70_18125	COG0697	spore germination
H1I70_18150	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I70_18155	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1I70_18160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I70_18165	COG0772	Belongs to the SEDS family
H1I70_18190	COG4974	Belongs to the 'phage' integrase family
H1I70_18195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I70_18205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1I70_18215	COG2197	response regulator
H1I70_18230	COG0793	Belongs to the peptidase S41A family
H1I70_18235	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1I70_18240	COG0795	lipopolysaccharide-transporting ATPase activity
H1I70_18280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I70_18280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I70_18290	COG0004	ammonium transporteR
H1I70_18295	COG0347	Belongs to the P(II) protein family
H1I70_18305	COG0606	chelatase, subunit chli
H1I70_18360	COG0659	secondary active sulfate transmembrane transporter activity
H1I70_18365	COG0589	response to stress
H1I70_18455	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I70_18485	COG0659	secondary active sulfate transmembrane transporter activity
H1I70_18490	COG0589	response to stress
H1I70_18520	COG0606	chelatase, subunit chli
H1I70_18525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I70_18535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I70_18550	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1I70_18565	COG0318	PFAM AMP-dependent synthetase and ligase
H1I70_18575	COG0477	Major facilitator Superfamily
H1I70_18580	COG2860	membrane
H1I70_18590	COG1253	flavin adenine dinucleotide binding
H1I70_18610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1I70_18645	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1I70_18655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1I70_18690	COG1309	transcriptional regulator
H1I70_18725	COG0758	DNA mediated transformation
H1I70_18735	COG0697	spore germination
H1I70_18740	COG1309	transcriptional regulator
H1I70_18755	COG0386	Belongs to the glutathione peroxidase family
H1I70_18820	COG1121	(ABC) transporter
H1I70_18825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1I70_18830	COG1280	lysine exporter protein (LysE YggA)
H1I70_18835	COG2837	iron assimilation
H1I70_18845	COG0281	malic enzyme
H1I70_18890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I70_18890	COG0519	Catalyzes the synthesis of GMP from XMP
H1I70_18895	COG4399	Belongs to the UPF0754 family
H1I70_18900	COG2259	Doxx family
H1I70_18905	COG0586	Pfam SNARE associated Golgi protein
H1I70_18920	COG1192	Involved in chromosome partitioning
H1I70_18930	COG0271	Belongs to the BolA IbaG family
H1I70_18950	COG2267	carboxylic ester hydrolase activity
H1I70_18970	COG3321	synthase
H1I70_18970	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1I70_18970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1I70_18970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I70_18975	COG1960	acyl-CoA dehydrogenase activity
H1I70_18985	COG2197	response regulator
H1I70_18995	COG3916	Acyl-homoserine-lactone synthase
H1I70_19000	COG0477	Major facilitator Superfamily
H1I70_19005	COG1024	Enoyl-CoA hydratase
H1I70_19010	COG1024	Enoyl-CoA hydratase
H1I70_19015	COG1960	acyl-CoA dehydrogenase activity
H1I70_19020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I70_19040	COG1113	amino acid transport
H1I70_19045	COG1113	amino acid transport
H1I70_19050	COG0251	oxidation-reduction process
H1I70_19090	COG0564	pseudouridine synthase activity
H1I70_19150	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1I70_19165	COG1802	Transcriptional regulator
H1I70_19175	COG1448	Aminotransferase
H1I70_19180	COG0277	FAD linked oxidase domain protein
H1I70_19190	COG2186	Transcriptional regulator
H1I70_19200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I70_19205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I70_19220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1I70_19225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1I70_19230	COG1216	Glycosyl transferase, family 2
H1I70_19260	COG2089	acid synthase
H1I70_19275	COG1083	cytidylyl-transferase
H1I70_19280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1I70_19285	COG1086	Polysaccharide biosynthesis protein
H1I70_19290	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1I70_19295	COG1596	polysaccharide export
H1I70_19320	COG0728	peptidoglycan biosynthetic process
H1I70_19325	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1I70_19380	COG0546	phosphoglycolate phosphatase activity
H1I70_19385	COG1028	Short-chain dehydrogenase reductase Sdr
H1I70_19405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I70_19410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I70_19415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I70_19420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I70_19425	COG1116	anion transmembrane transporter activity
H1I70_19430	COG1309	transcriptional regulator
H1I70_19435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1I70_19445	COG0196	riboflavin kinase activity
H1I70_19450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1I70_19460	COG1047	Peptidyl-prolyl cis-trans
H1I70_19500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1I70_19505	COG0657	acetylesterase activity
H1I70_19555	COG2951	lytic endotransglycosylase activity
H1I70_19560	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1I70_19575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1I70_19585	COG0671	phosphoesterase, PA-phosphatase related
H1I70_19590	COG0861	Integral membrane protein TerC family
H1I70_19600	COG0754	glutathionylspermidine amidase activity
H1I70_19610	COG0402	S-adenosylhomocysteine deaminase activity
H1I70_19625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I70_19630	COG1230	cation diffusion facilitator family transporter
H1I70_19645	COG0706	membrane insertase activity