locus-tag	class	description
H1I69_00010	COG0592	DNA-directed DNA polymerase activity
H1I69_00020	COG0187	DNA topoisomerase II activity
H1I69_00030	COG0586	Pfam SNARE associated Golgi protein
H1I69_00035	COG0488	(ABC) transporter
H1I69_00060	COG0596	Alpha beta hydrolase
H1I69_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1I69_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1I69_00110	COG0733	neurotransmitter:sodium symporter activity
H1I69_00145	COG0583	DNA-binding transcription factor activity
H1I69_00150	COG2233	PERMEase
H1I69_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I69_00215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I69_00220	COG1064	alcohol dehydrogenase
H1I69_00225	COG2818	Glycosylase
H1I69_00240	COG1194	a g-specific adenine glycosylase
H1I69_00260	COG2983	Belongs to the UPF0260 family
H1I69_00265	COG2133	pyrroloquinoline quinone binding
H1I69_00270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1I69_00275	COG2116	formate transmembrane transporter activity
H1I69_00295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I69_00300	COG1335	isochorismatase
H1I69_00305	COG0385	Bile acid
H1I69_00310	COG0534	Mate efflux family protein
H1I69_00315	COG1683	Conserved Protein
H1I69_00335	COG0625	glutathione transferase activity
H1I69_00345	COG1113	amino acid transport
H1I69_00355	COG0523	cobalamin synthesis protein
H1I69_00365	COG2188	Transcriptional regulator
H1I69_00395	COG0010	Belongs to the arginase family
H1I69_00415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I69_00420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1I69_00430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1I69_00435	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1I69_00535	COG0534	Mate efflux family protein
H1I69_00540	COG0436	Aminotransferase
H1I69_00545	COG2733	membrane
H1I69_00560	COG2918	glutathione biosynthetic process
H1I69_00580	COG0791	NLP P60 protein
H1I69_00580	COG1388	LysM domain
H1I69_00595	COG3150	esterase
H1I69_00605	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H1I69_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I69_00630	COG2233	PERMEase
H1I69_00635	COG2351	hydroxyisourate hydrolase activity
H1I69_00670	COG3706	GGDEF domain
H1I69_00685	COG1393	Belongs to the ArsC family
H1I69_00690	COG0708	Exodeoxyribonuclease III
H1I69_00710	COG0189	ligase activity
H1I69_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1I69_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1I69_00755	COG4942	peptidase
H1I69_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I69_00775	COG2119	membrane
H1I69_00780	COG4774	siderophore transport
H1I69_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I69_00785	COG0426	domain, Protein
H1I69_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1I69_00830	COG1902	pentaerythritol trinitrate reductase activity
H1I69_00835	COG1519	Transferase
H1I69_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I69_00845	COG0668	transmembrane transport
H1I69_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I69_00860	COG1335	isochorismatase
H1I69_00865	COG1522	sequence-specific DNA binding
H1I69_00870	COG3328	transposase activity
H1I69_00895	COG2198	Histidine kinase
H1I69_00895	COG2205	protein histidine kinase activity
H1I69_00895	COG0784	Response regulator, receiver
H1I69_00900	COG3162	membrane
H1I69_00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I69_00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I69_00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1I69_00940	COG1309	transcriptional regulator
H1I69_00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I69_00960	COG0352	thiamine-phosphate diphosphorylase activity
H1I69_00960	COG0351	phosphomethylpyrimidine kinase
H1I69_00970	COG2814	Major facilitator Superfamily
H1I69_01005	COG1002	Type II restriction enzyme, methylase subunits
H1I69_01015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I69_01030	COG1002	Type II restriction enzyme, methylase subunits
H1I69_01040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I69_01050	COG1113	amino acid transport
H1I69_01060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I69_01065	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_01075	COG1335	isochorismatase
H1I69_01105	COG2814	Major facilitator Superfamily
H1I69_01110	COG0583	DNA-binding transcription factor activity
H1I69_01130	COG0667	Aldo Keto reductase
H1I69_01160	COG1733	regulation of RNA biosynthetic process
H1I69_01165	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I69_01230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1I69_01245	COG2329	Antibiotic biosynthesis monooxygenase
H1I69_01275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1I69_01305	COG0427	acetyl-CoA hydrolase
H1I69_01330	COG0659	secondary active sulfate transmembrane transporter activity
H1I69_01335	COG4221	oxidoreductase activity
H1I69_01340	COG2873	o-acetylhomoserine
H1I69_01345	COG0488	(ABC) transporter
H1I69_01425	COG0833	amino acid
H1I69_01470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1I69_01475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1I69_01490	COG2226	methyltransferase
H1I69_01540	COG0067	glutamate synthase
H1I69_01540	COG0069	glutamate synthase activity
H1I69_01540	COG0070	glutamate synthase
H1I69_01545	COG0493	'glutamate synthase
H1I69_01555	COG1704	LemA family
H1I69_01560	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1I69_01575	COG4969	Belongs to the N-Me-Phe pilin family
H1I69_01600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I69_01615	COG0194	GDP metabolic process
H1I69_01665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1I69_01685	COG5380	lipid catabolic process
H1I69_01690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1I69_01715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1I69_01720	COG0277	FAD linked oxidase domain protein
H1I69_01730	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1I69_01735	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I69_01750	COG1289	transmembrane transporter activity
H1I69_01760	COG0628	permease
H1I69_01765	COG1192	Involved in chromosome partitioning
H1I69_01795	COG0833	amino acid
H1I69_01800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I69_01805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I69_01815	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_01855	COG0583	DNA-binding transcription factor activity
H1I69_01900	COG0517	IMP dehydrogenase activity
H1I69_01905	COG1983	PspC domain protein
H1I69_01915	COG1960	acyl-CoA dehydrogenase activity
H1I69_01930	COG0408	coproporphyrinogen oxidase activity
H1I69_01950	COG0513	Belongs to the DEAD box helicase family
H1I69_01960	COG1127	ABC transporter
H1I69_01965	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1I69_01975	COG2854	intermembrane phospholipid transfer
H1I69_01985	COG0598	Magnesium transport protein CorA
H1I69_01995	COG0494	nUDIX hydrolase
H1I69_02000	COG1040	competence protein
H1I69_02005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1I69_02025	COG1946	Acyl-CoA thioesterase
H1I69_02030	COG1301	dicarboxylic acid transport
H1I69_02045	COG1959	2 iron, 2 sulfur cluster binding
H1I69_02050	COG1017	nitric oxide dioxygenase activity
H1I69_02050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I69_02055	COG0433	COG0433 Predicted ATPase
H1I69_02060	COG0626	cystathionine gamma-synthase activity
H1I69_02215	COG1960	acyl-CoA dehydrogenase activity
H1I69_02220	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1I69_02250	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1I69_02255	COG0339	signal peptide processing
H1I69_02260	COG0557	exoribonuclease II activity
H1I69_02300	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1I69_02305	COG2169	Transcriptional regulator
H1I69_02310	COG0697	spore germination
H1I69_02315	COG1295	ribonuclease BN
H1I69_02350	COG1702	phosphate starvation-inducible protein PhoH
H1I69_02360	COG0739	heme binding
H1I69_02360	COG0741	lytic transglycosylase activity
H1I69_02360	COG1196	nuclear chromosome segregation
H1I69_02390	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1I69_02395	COG1183	phosphatidylcholine synthase activity
H1I69_02440	COG1960	acyl-CoA dehydrogenase activity
H1I69_02445	COG1309	transcriptional regulator
H1I69_02460	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I69_02465	COG1960	acyl-CoA dehydrogenase activity
H1I69_02485	COG2969	positive regulation of protein catabolic process
H1I69_02495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1I69_02510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1I69_02515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1I69_02535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1I69_02545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I69_02550	COG1408	metallophosphoesterase
H1I69_02560	COG2199	diguanylate cyclase activity
H1I69_02620	COG1607	acyl-coa hydrolase
H1I69_02650	COG2350	Protein conserved in bacteria
H1I69_02660	COG0613	PHP domain protein
H1I69_02665	COG3781	membrane
H1I69_02675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1I69_02680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1I69_02690	COG1862	Preprotein translocase
H1I69_02720	COG2205	protein histidine kinase activity
H1I69_02725	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H1I69_02745	COG0726	polysaccharide deacetylase
H1I69_02750	COG0463	Glycosyl transferase, family 2
H1I69_02755	COG0438	transferase activity, transferring glycosyl groups
H1I69_02820	COG0625	glutathione transferase activity
H1I69_02825	COG0583	DNA-binding transcription factor activity
H1I69_02830	COG1960	acyl-CoA dehydrogenase activity
H1I69_02835	COG1960	acyl-CoA dehydrogenase activity
H1I69_02845	COG2205	protein histidine kinase activity
H1I69_02850	COG0745	RESPONSE REGULATOR receiver
H1I69_02855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H1I69_02875	COG2096	Adenosyltransferase
H1I69_02925	COG0285	dihydrofolate synthase activity
H1I69_02945	COG0450	alkyl hydroperoxide reductase
H1I69_02960	COG0477	Major facilitator Superfamily
H1I69_02965	COG1272	protein, Hemolysin III
H1I69_02995	COG0183	Belongs to the thiolase family
H1I69_03000	COG2207	Transcriptional regulator
H1I69_03020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I69_03040	COG0183	Belongs to the thiolase family
H1I69_03050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1I69_03050	COG2885	chlorophyll binding
H1I69_03060	COG1690	Belongs to the RtcB family
H1I69_03065	COG0833	amino acid
H1I69_03075	COG2233	PERMEase
H1I69_03080	COG1217	gtp-binding protein TYPA
H1I69_03105	COG2094	Belongs to the DNA glycosylase MPG family
H1I69_03110	COG4772	TonB-dependent receptor
H1I69_03125	COG1902	pentaerythritol trinitrate reductase activity
H1I69_03140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I69_03145	COG0354	folic acid binding
H1I69_03155	COG3189	MarR family transcriptional regulator
H1I69_03160	COG2824	Alkylphosphonate utilization operon protein PhnA
H1I69_03165	COG3422	double-strand break repair
H1I69_03205	COG0840	transmembrane signaling receptor activity
H1I69_03225	COG5510	response to toxic substance
H1I69_03235	COG2832	Protein of unknown function (DUF454)
H1I69_03240	COG1376	ErfK ybiS ycfS ynhG family protein
H1I69_03280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1I69_03290	COG1289	transmembrane transporter activity
H1I69_03295	COG2814	Major facilitator Superfamily
H1I69_03315	COG1115	amino acid carrier protein
H1I69_03320	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I69_03325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I69_03330	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1I69_03360	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I69_03370	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I69_03375	COG1077	Cell shape determining protein MreB Mrl
H1I69_03380	COG1792	Involved in formation and maintenance of cell shape
H1I69_03385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1I69_03390	COG0424	maF-like protein
H1I69_03395	COG1530	ribonuclease E activity
H1I69_03405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I69_03415	COG0560	Phosphoserine phosphatase
H1I69_03425	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I69_03450	COG2207	Transcriptional regulator
H1I69_03470	COG1113	amino acid transport
H1I69_03475	COG2828	Protein conserved in bacteria
H1I69_03480	COG0142	geranyltranstransferase activity
H1I69_03485	COG2315	Protein conserved in bacteria
H1I69_03500	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I69_03520	COG2194	sulfuric ester hydrolase activity
H1I69_03525	COG0745	RESPONSE REGULATOR receiver
H1I69_03530	COG0642	Histidine kinase
H1I69_03540	COG0004	ammonium transporteR
H1I69_03545	COG0583	DNA-binding transcription factor activity
H1I69_03565	COG0525	valine-tRNA ligase activity
H1I69_03575	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_03585	COG0393	Putative heavy-metal-binding
H1I69_03590	COG0393	Putative heavy-metal-binding
H1I69_03595	COG1538	Outer membrane efflux protein
H1I69_03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I69_03610	COG0671	phosphoesterase, PA-phosphatase related
H1I69_03640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1I69_03655	COG1648	precorrin-2 dehydrogenase activity
H1I69_03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1I69_03660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1I69_03665	COG1733	regulation of RNA biosynthetic process
H1I69_03675	COG0531	amino acid
H1I69_03695	COG0321	lipoyl(octanoyl) transferase activity
H1I69_03700	COG2921	Belongs to the UPF0250 family
H1I69_03740	COG2009	succinate dehydrogenase
H1I69_03745	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1I69_03750	COG1053	succinate dehydrogenase
H1I69_03755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1I69_03780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I69_03800	COG2354	Protein conserved in bacteria
H1I69_03805	COG2321	neutral zinc metallopeptidase
H1I69_03840	COG2843	Capsule synthesis protein
H1I69_03855	COG0589	response to stress
H1I69_03875	COG0505	Belongs to the CarA family
H1I69_03900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I69_03905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1I69_03955	COG0477	Major facilitator Superfamily
H1I69_03960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1I69_03975	COG1597	lipid kinase activity
H1I69_03980	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I69_04010	COG0584	glycerophosphoryl diester phosphodiesterase
H1I69_04030	COG0741	lytic transglycosylase activity
H1I69_04050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1I69_04065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I69_04090	COG0778	Nitroreductase
H1I69_04105	COG1929	Belongs to the glycerate kinase type-1 family
H1I69_04110	COG0243	molybdopterin cofactor binding
H1I69_04115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1I69_04120	COG3339	Conserved Protein
H1I69_04130	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H1I69_04145	COG1113	amino acid transport
H1I69_04155	COG0019	diaminopimelate decarboxylase activity
H1I69_04165	COG1280	lysine exporter protein (LysE YggA)
H1I69_04170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I69_04200	COG0463	Glycosyl transferase, family 2
H1I69_04220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I69_04255	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1I69_04260	COG1136	(ABC) transporter
H1I69_04265	COG2333	competence protein COMEC
H1I69_04265	COG0658	competence protein
H1I69_04275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1I69_04275	COG0616	signal peptide processing
H1I69_04280	COG0596	Alpha beta hydrolase
H1I69_04285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1I69_04295	COG0628	permease
H1I69_04330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I69_04350	COG0823	Involved in the tonB-independent uptake of proteins
H1I69_04370	COG0824	Thioesterase
H1I69_04375	COG1473	amidohydrolase
H1I69_04395	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1I69_04395	COG0047	phosphoribosylformylglycinamidine synthase activity
H1I69_04400	COG2814	Major facilitator Superfamily
H1I69_04410	COG1024	Enoyl-CoA hydratase
H1I69_04415	COG1051	belongs to the nudix hydrolase family
H1I69_04415	COG1056	cytidyltransferase-related domain
H1I69_04425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1I69_04440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1I69_04455	COG4625	pathogenesis
H1I69_04460	COG0583	DNA-binding transcription factor activity
H1I69_04465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1I69_04470	COG4208	sulfate ABC transporter
H1I69_04475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1I69_04485	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1I69_04490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1I69_04495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1I69_04515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I69_04530	COG0681	Belongs to the peptidase S26 family
H1I69_04545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1I69_04555	COG1381	Involved in DNA repair and RecF pathway recombination
H1I69_04560	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1I69_04570	COG4221	oxidoreductase activity
H1I69_04600	COG0436	Aminotransferase
H1I69_04620	COG0556	nucleotide-excision repair
H1I69_04675	COG2070	2-Nitropropane dioxygenase
H1I69_04705	COG1215	transferase activity, transferring glycosyl groups
H1I69_04720	COG0415	Belongs to the DNA photolyase family
H1I69_04730	COG1252	NADH dehydrogenase
H1I69_04735	COG1686	Belongs to the peptidase S11 family
H1I69_04750	COG1187	pseudouridine synthase activity
H1I69_04775	COG0477	Major facilitator Superfamily
H1I69_04780	COG0583	DNA-binding transcription factor activity
H1I69_04795	COG0612	Peptidase, M16
H1I69_04820	COG0352	thiamine-phosphate diphosphorylase activity
H1I69_04855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I69_04870	COG1309	transcriptional regulator
H1I69_04880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I69_04885	COG0076	glutamate decarboxylase activity
H1I69_04895	COG1522	sequence-specific DNA binding
H1I69_04900	COG3961	Belongs to the TPP enzyme family
H1I69_04905	COG1113	amino acid transport
H1I69_04910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I69_04915	COG0573	inorganic phosphate transmembrane transporter activity
H1I69_04925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1I69_04930	COG0616	signal peptide processing
H1I69_04940	COG3328	transposase activity
H1I69_04970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1I69_04975	COG1686	Belongs to the peptidase S11 family
H1I69_05000	COG0583	DNA-binding transcription factor activity
H1I69_05005	COG1067	ATP-dependent peptidase activity
H1I69_05050	COG1966	Carbon starvation protein
H1I69_05055	COG2879	small protein
H1I69_05085	COG2508	Transcriptional regulator
H1I69_05085	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1I69_05105	COG1113	amino acid transport
H1I69_05110	COG0583	DNA-binding transcription factor activity
H1I69_05115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I69_05120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I69_05130	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_05135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I69_05140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I69_05140	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H1I69_05175	COG2814	Major facilitator Superfamily
H1I69_05180	COG4948	Mandelate Racemase Muconate Lactonizing
H1I69_05190	COG1309	transcriptional regulator
H1I69_05210	COG1741	Belongs to the pirin family
H1I69_05220	COG2964	Protein conserved in bacteria
H1I69_05235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I69_05240	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I69_05245	COG4605	iron ion homeostasis
H1I69_05250	COG4604	ABC transporter, ATP-binding protein
H1I69_05255	COG4607	ABC-type enterochelin transport system periplasmic component
H1I69_05260	COG4774	siderophore transport
H1I69_05270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I69_05275	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1I69_05280	COG1535	isochorismatase
H1I69_05280	COG3433	isochorismatase activity
H1I69_05295	COG1132	(ABC) transporter
H1I69_05300	COG1132	(ABC) transporter
H1I69_05305	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H1I69_05315	COG1169	isochorismate synthase
H1I69_05330	COG3739	integral membrane protein
H1I69_05355	COG0302	gtp cyclohydrolase
H1I69_05365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1I69_05395	COG0308	aminopeptidase N
H1I69_05400	COG0512	Glutamine amidotransferase of anthranilate synthase
H1I69_05415	COG0174	glutamine synthetase
H1I69_05425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H1I69_05460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1I69_05465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1I69_05470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I69_05490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I69_05495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1I69_05500	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1I69_05515	COG1960	acyl-CoA dehydrogenase activity
H1I69_05520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I69_05525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I69_05535	COG2223	nitrite transmembrane transporter activity
H1I69_05545	COG0024	Methionine aminopeptidase
H1I69_05550	COG0052	Belongs to the universal ribosomal protein uS2 family
H1I69_05565	COG2207	Transcriptional regulator
H1I69_05590	COG2951	lytic endotransglycosylase activity
H1I69_05595	COG0772	Belongs to the SEDS family
H1I69_05610	COG0842	Transport permease protein
H1I69_05615	COG1131	(ABC) transporter
H1I69_05660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I69_05675	COG4215	(ABC) transporter
H1I69_05680	COG4160	amino acid transport
H1I69_05685	COG4598	ABC transporter
H1I69_05695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I69_05700	COG0826	peptidase U32
H1I69_05705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I69_05720	COG1720	tRNA m6t6A37 methyltransferase activity
H1I69_05730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1I69_05745	COG0642	Histidine kinase
H1I69_05755	COG0494	nUDIX hydrolase
H1I69_05765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1I69_05770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1I69_05775	COG3139	Protein of unknown function (DUF1315)
H1I69_05780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1I69_05785	COG1301	dicarboxylic acid transport
H1I69_05790	COG1960	acyl-CoA dehydrogenase activity
H1I69_05795	COG2819	hydrolase of the alpha beta superfamily
H1I69_05805	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1I69_05815	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1I69_05820	COG1234	tRNA 3'-trailer cleavage
H1I69_05850	COG2363	Small membrane protein
H1I69_05870	COG0513	Belongs to the DEAD box helicase family
H1I69_05880	COG0778	Nitroreductase
H1I69_05910	COG1286	toxin biosynthetic process
H1I69_05935	COG4783	chaperone-mediated protein folding
H1I69_05940	COG1610	YqeY-like protein
H1I69_06040	COG3111	PFAM Bacterial OB fold (BOF) protein
H1I69_06065	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1I69_06070	COG0786	glutamate:sodium symporter activity
H1I69_06080	COG2186	Transcriptional regulator
H1I69_06130	COG0477	Major facilitator Superfamily
H1I69_06155	COG2985	domain, Protein
H1I69_06165	COG2995	paraquat-inducible protein a
H1I69_06170	COG3008	intermembrane lipid transfer
H1I69_06170	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1I69_06190	COG0482	sulfurtransferase activity
H1I69_06205	COG0488	(ABC) transporter
H1I69_06210	COG3173	Aminoglycoside phosphotransferase
H1I69_06220	COG2433	Pfam Transposase IS66
H1I69_06355	COG0590	tRNA wobble adenosine to inosine editing
H1I69_06360	COG2807	transmembrane transport
H1I69_06375	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1I69_06390	COG0789	Transcriptional regulator
H1I69_06400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I69_06420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I69_06430	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I69_06445	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_06450	COG0531	amino acid
H1I69_06455	COG1760	l-serine dehydratase
H1I69_06460	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_06460	COG2030	dehydratase
H1I69_06465	COG3396	Phenylacetate-CoA oxygenase
H1I69_06470	COG3460	Phenylacetate-CoA oxygenase
H1I69_06475	COG3396	Phenylacetate-CoA oxygenase
H1I69_06480	COG2151	metal-sulfur cluster biosynthetic enzyme
H1I69_06485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I69_06490	COG1024	Enoyl-CoA hydratase
H1I69_06495	COG1024	Enoyl-CoA hydratase
H1I69_06500	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I69_06505	COG0183	Belongs to the thiolase family
H1I69_06510	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H1I69_06515	COG3327	negative regulation of DNA-templated transcription, initiation
H1I69_06525	COG2050	protein possibly involved in aromatic compounds catabolism
H1I69_06560	COG0753	catalase activity
H1I69_06565	COG3038	cytochrome b561
H1I69_06585	COG2267	carboxylic ester hydrolase activity
H1I69_06590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I69_06595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I69_06600	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_06610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I69_06620	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_06625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I69_06630	COG0583	DNA-binding transcription factor activity
H1I69_06640	COG1414	Transcriptional regulator
H1I69_06645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I69_06655	COG1840	ABC-type Fe3 transport system, periplasmic component
H1I69_06660	COG3842	ATPase activity
H1I69_06675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H1I69_06680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I69_06685	COG2814	Major facilitator Superfamily
H1I69_06690	COG1960	acyl-CoA dehydrogenase activity
H1I69_06705	COG1024	Enoyl-CoA hydratase
H1I69_06715	COG2814	Major facilitator Superfamily
H1I69_06725	COG0183	Belongs to the thiolase family
H1I69_06730	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I69_06735	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_06740	COG1024	Enoyl-CoA hydratase
H1I69_06745	COG1960	acyl-CoA dehydrogenase activity
H1I69_06750	COG2814	Major facilitator Superfamily
H1I69_06755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I69_06760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I69_06770	COG2814	Major facilitator Superfamily
H1I69_06780	COG1960	acyl-CoA dehydrogenase activity
H1I69_06795	COG0583	DNA-binding transcription factor activity
H1I69_06805	COG4770	biotin carboxylase activity
H1I69_06810	COG1024	Enoyl-CoA hydratase
H1I69_06815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I69_06820	COG1960	acyl-CoA dehydrogenase activity
H1I69_06825	COG1309	transcriptional regulator
H1I69_06830	COG0318	PFAM AMP-dependent synthetase and ligase
H1I69_06850	COG0583	DNA-binding transcription factor activity
H1I69_06900	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_06920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I69_06940	COG2205	protein histidine kinase activity
H1I69_06940	COG0784	Response regulator, receiver
H1I69_06960	COG0765	amino acid transport
H1I69_06965	COG0765	amino acid transport
H1I69_06970	COG1126	abc transporter atp-binding protein
H1I69_06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I69_06980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I69_06995	COG1280	lysine exporter protein (LysE YggA)
H1I69_07005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1I69_07010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I69_07015	COG1045	serine acetyltransferase
H1I69_07030	COG0583	DNA-binding transcription factor activity
H1I69_07035	COG0625	glutathione transferase activity
H1I69_07040	COG0625	glutathione transferase activity
H1I69_07045	COG0583	DNA-binding transcription factor activity
H1I69_07055	COG1346	cytolysis
H1I69_07075	COG2814	Major facilitator Superfamily
H1I69_07085	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H1I69_07090	COG3052	prosthetic group binding
H1I69_07110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1I69_07130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I69_07140	COG1294	oxidase, subunit
H1I69_07145	COG1271	oxidase subunit
H1I69_07170	COG0477	Major facilitator Superfamily
H1I69_07180	COG4521	taurine ABC transporter
H1I69_07185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1I69_07190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I69_07195	COG2175	clavaminate synthase activity
H1I69_07205	COG1953	Uracil, thiamine, allantoin
H1I69_07215	COG0583	DNA-binding transcription factor activity
H1I69_07225	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1I69_07240	COG0640	Transcriptional regulator
H1I69_07245	COG0798	PFAM Bile acid sodium symporter
H1I69_07250	COG0583	DNA-binding transcription factor activity
H1I69_07265	COG3634	alkyl hydroperoxide reductase activity
H1I69_07305	COG0436	Aminotransferase
H1I69_07315	COG0386	Belongs to the glutathione peroxidase family
H1I69_07355	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I69_07380	COG0012	GTP binding
H1I69_07385	COG2011	ABC-type metal ion transport system permease component
H1I69_07390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I69_07400	COG1464	Belongs to the NlpA lipoprotein family
H1I69_07430	COG0765	amino acid transport
H1I69_07435	COG0765	amino acid transport
H1I69_07440	COG1126	abc transporter atp-binding protein
H1I69_07450	COG1522	sequence-specific DNA binding
H1I69_07465	COG1309	transcriptional regulator
H1I69_07485	COG0583	DNA-binding transcription factor activity
H1I69_07495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I69_07505	COG0697	spore germination
H1I69_07530	COG3121	Chaperone
H1I69_07535	COG3539	Fimbrial protein
H1I69_07560	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1I69_07560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1I69_07605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1I69_07615	COG2353	YceI-like domain
H1I69_07625	COG3698	Phosphodiester glycosidase
H1I69_07640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H1I69_07645	COG0506	proline dehydrogenase activity
H1I69_07645	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I69_07645	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I69_07655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I69_07660	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1I69_07680	COG1132	(ABC) transporter
H1I69_07685	COG3122	Protein conserved in bacteria
H1I69_07690	COG3619	membrane
H1I69_07705	COG0640	Transcriptional regulator
H1I69_07715	COG2850	peptidyl-arginine hydroxylation
H1I69_07720	COG0424	maF-like protein
H1I69_07740	COG0191	fructose-bisphosphate aldolase activity
H1I69_07745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I69_07760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1I69_07770	COG1192	Involved in chromosome partitioning
H1I69_07775	COG1475	DNA binding
H1I69_07780	COG0811	peptide transport
H1I69_07790	COG1132	(ABC) transporter
H1I69_07795	COG1663	tetraacyldisaccharide 4'-kinase activity
H1I69_07815	COG0084	hydrolase, TatD family'
H1I69_07880	COG0776	regulation of translation
H1I69_07910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1I69_07915	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1I69_07965	COG0339	signal peptide processing
H1I69_07975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1I69_08010	COG0702	epimerase
H1I69_08015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I69_08035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1I69_08065	COG0316	Belongs to the HesB IscA family
H1I69_08070	COG0822	iron-sulfur transferase activity
H1I69_08095	COG0776	regulation of translation
H1I69_08100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I69_08105	COG2207	Transcriptional regulator
H1I69_08110	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I69_08115	COG1960	acyl-CoA dehydrogenase activity
H1I69_08120	COG1960	acyl-CoA dehydrogenase activity
H1I69_08135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1I69_08155	COG4264	IucA IucC family
H1I69_08160	COG4264	IucA IucC family
H1I69_08200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I69_08215	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H1I69_08235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1I69_08240	COG0730	response to heat
H1I69_08260	COG4773	Receptor
H1I69_08265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I69_08280	COG1131	(ABC) transporter
H1I69_08285	COG0842	Transport permease protein
H1I69_08290	COG0842	Transport permease protein
H1I69_08345	COG2226	methyltransferase
H1I69_08370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1I69_08405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I69_08415	COG0133	tryptophan synthase activity
H1I69_08430	COG3706	GGDEF domain
H1I69_08445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I69_08450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1I69_08455	COG0022	dehydrogenase e1 component
H1I69_08460	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I69_08465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I69_08475	COG1063	alcohol dehydrogenase
H1I69_08480	COG3781	membrane
H1I69_08490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I69_08490	COG3453	Protein conserved in bacteria
H1I69_08500	COG0730	response to heat
H1I69_08520	COG2207	Transcriptional regulator
H1I69_08520	COG3708	Transcriptional regulator
H1I69_08525	COG1733	regulation of RNA biosynthetic process
H1I69_08530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1I69_08540	COG2188	Transcriptional regulator
H1I69_08555	COG4521	taurine ABC transporter
H1I69_08560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I69_08580	COG0477	Major facilitator Superfamily
H1I69_08590	COG1027	Aspartate ammonia-lyase
H1I69_08605	COG0583	DNA-binding transcription factor activity
H1I69_08610	COG0583	DNA-binding transcription factor activity
H1I69_08615	COG0183	Belongs to the thiolase family
H1I69_08620	COG2031	fatty acid transporter
H1I69_08625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I69_08635	COG0583	DNA-binding transcription factor activity
H1I69_08645	COG2610	gluconate transmembrane transporter activity
H1I69_08650	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_08660	COG2207	Transcriptional regulator
H1I69_08675	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_08700	COG0543	2 iron, 2 sulfur cluster binding
H1I69_08700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I69_08705	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I69_08710	COG4638	Rieske (2fe-2S)
H1I69_08720	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1I69_08725	COG4149	molybdate abc transporter
H1I69_08730	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1I69_08735	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_08740	COG3433	isochorismatase activity
H1I69_08740	COG1535	isochorismatase
H1I69_08805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I69_08820	COG0753	catalase activity
H1I69_08830	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H1I69_08860	COG3539	Fimbrial protein
H1I69_08880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I69_08900	COG2072	flavoprotein involved in K transport
H1I69_08910	COG1538	Outer membrane efflux protein
H1I69_08915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I69_08920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I69_08925	COG0745	RESPONSE REGULATOR receiver
H1I69_08930	COG2205	protein histidine kinase activity
H1I69_08940	COG2207	Transcriptional regulator
H1I69_08955	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_09005	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H1I69_09120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I69_09140	COG1120	ATPase activity
H1I69_09145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I69_09155	COG1064	alcohol dehydrogenase
H1I69_09170	COG2207	Transcriptional regulator
H1I69_09175	COG2084	Dehydrogenase
H1I69_09185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1I69_09190	COG0583	DNA-binding transcription factor activity
H1I69_09200	COG0129	dihydroxy-acid dehydratase activity
H1I69_09205	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_09220	COG1566	PFAM secretion protein HlyD family protein
H1I69_09240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I69_09270	COG0583	DNA-binding transcription factor activity
H1I69_09285	COG2188	Transcriptional regulator
H1I69_09315	COG3210	domain, Protein
H1I69_09320	COG2831	hemolysin activation secretion protein
H1I69_09335	COG1473	amidohydrolase
H1I69_09345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I69_09345	COG0475	glutathione-regulated potassium exporter activity
H1I69_09355	COG0583	DNA-binding transcription factor activity
H1I69_09360	COG1335	isochorismatase
H1I69_09370	COG1309	transcriptional regulator
H1I69_09400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1I69_09410	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I69_09410	COG1902	pentaerythritol trinitrate reductase activity
H1I69_09415	COG1846	Transcriptional regulator
H1I69_09435	COG0753	catalase activity
H1I69_09450	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_09465	COG3162	membrane
H1I69_09475	COG3829	transcription factor binding
H1I69_09480	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_09485	COG1960	acyl-CoA dehydrogenase activity
H1I69_09505	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_09525	COG2186	Transcriptional regulator
H1I69_09535	COG0583	DNA-binding transcription factor activity
H1I69_09540	COG4948	Mandelate Racemase Muconate Lactonizing
H1I69_09545	COG4829	muconolactone delta-isomerase
H1I69_09555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I69_09560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I69_09565	COG0183	Belongs to the thiolase family
H1I69_09570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I69_09580	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_09590	COG3733	amine oxidase
H1I69_09600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I69_09610	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_09620	COG4638	Rieske (2fe-2S)
H1I69_09640	COG0154	amidase activity
H1I69_09650	COG2814	Major facilitator Superfamily
H1I69_09675	COG1960	acyl-CoA dehydrogenase activity
H1I69_09680	COG0583	DNA-binding transcription factor activity
H1I69_09685	COG1414	Transcriptional regulator
H1I69_09700	COG2391	methyltransferase activity
H1I69_09710	COG4993	Dehydrogenase
H1I69_09715	COG3659	wide pore channel activity
H1I69_09720	COG3420	alginic acid biosynthetic process
H1I69_09725	COG0710	3-dehydroquinate dehydratase activity
H1I69_09730	COG3485	protocatechuate 3,4-dioxygenase
H1I69_09735	COG3485	protocatechuate 3,4-dioxygenase
H1I69_09740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I69_09745	COG2271	Major facilitator Superfamily
H1I69_09750	COG0596	Alpha beta hydrolase
H1I69_09755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1I69_09760	COG0183	Belongs to the thiolase family
H1I69_09765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I69_09770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I69_09780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1I69_09785	COG2323	membrane
H1I69_09830	COG1902	pentaerythritol trinitrate reductase activity
H1I69_09830	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I69_09855	COG0542	response to heat
H1I69_09860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1I69_09890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I69_09895	COG0569	domain protein
H1I69_09900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1I69_09915	COG4774	siderophore transport
H1I69_09920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1I69_09930	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1I69_09945	COG1294	oxidase, subunit
H1I69_09950	COG4890	Cyd operon protein YbgT
H1I69_09965	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H1I69_09975	COG0552	protein localization to endoplasmic reticulum
H1I69_10000	COG0516	GMP reductase activity
H1I69_10000	COG0517	IMP dehydrogenase activity
H1I69_10005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I69_10010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1I69_10020	COG0583	DNA-binding transcription factor activity
H1I69_10025	COG0024	Methionine aminopeptidase
H1I69_10055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1I69_10055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I69_10060	COG1105	Belongs to the carbohydrate kinase PfkB family
H1I69_10065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I69_10065	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1I69_10065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I69_10085	COG3300	MHYT domain
H1I69_10085	COG5001	Diguanylate cyclase
H1I69_10100	COG2135	peptidase activity
H1I69_10105	COG0659	secondary active sulfate transmembrane transporter activity
H1I69_10120	COG1113	amino acid transport
H1I69_10130	COG1522	sequence-specific DNA binding
H1I69_10155	COG1011	Hydrolase
H1I69_10160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1I69_10170	COG2137	regulation of response to DNA damage stimulus
H1I69_10185	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I69_10220	COG0575	Belongs to the CDS family
H1I69_10225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1I69_10250	COG3852	Histidine kinase
H1I69_10255	COG2204	response regulator
H1I69_10310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I69_10315	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1I69_10335	COG0697	spore germination
H1I69_10340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I69_10350	COG0303	'Molybdopterin
H1I69_10355	COG0315	cyclic pyranopterin monophosphate synthase activity
H1I69_10355	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1I69_10370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1I69_10375	COG0243	molybdopterin cofactor binding
H1I69_10385	COG0243	molybdopterin cofactor binding
H1I69_10390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I69_10395	COG2146	nitrite reductase [NAD(P)H] activity
H1I69_10395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I69_10405	COG0745	RESPONSE REGULATOR receiver
H1I69_10410	COG1116	anion transmembrane transporter activity
H1I69_10410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I69_10430	COG0511	ligase activity, forming carbon-carbon bonds
H1I69_10445	COG2814	Major facilitator Superfamily
H1I69_10650	COG5410	chromosome segregation
H1I69_10820	COG0069	glutamate synthase activity
H1I69_10840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1I69_10850	COG1454	alcohol dehydrogenase
H1I69_10855	COG0824	Thioesterase
H1I69_10865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1I69_10880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I69_10885	COG2030	dehydratase
H1I69_10895	COG0183	Belongs to the thiolase family
H1I69_10905	COG0583	DNA-binding transcription factor activity
H1I69_10910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1I69_10920	COG1522	sequence-specific DNA binding
H1I69_10925	COG3135	benzoate transporter
H1I69_10935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1I69_10960	COG0589	response to stress
H1I69_10965	COG0488	(ABC) transporter
H1I69_10985	COG4773	Receptor
H1I69_11020	COG0668	transmembrane transport
H1I69_11030	COG1309	transcriptional regulator
H1I69_11045	COG1605	Chorismate mutase
H1I69_11075	COG0308	aminopeptidase N
H1I69_11095	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1I69_11105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I69_11110	COG1454	alcohol dehydrogenase
H1I69_11130	COG0531	amino acid
H1I69_11135	COG4303	Ethanolamine ammonia lyase large subunit
H1I69_11140	COG4302	ethanolamine ammonia-lyase activity
H1I69_11145	COG0519	Catalyzes the synthesis of GMP from XMP
H1I69_11145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I69_11150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I69_11160	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I69_11175	COG0697	spore germination
H1I69_11180	COG1923	regulation of RNA biosynthetic process
H1I69_11190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1I69_11195	COG0802	atpase or kinase
H1I69_11215	COG1187	pseudouridine synthase activity
H1I69_11230	COG0583	DNA-binding transcription factor activity
H1I69_11245	COG2814	Major facilitator Superfamily
H1I69_11250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I69_11275	COG0729	surface antigen
H1I69_11295	COG0174	glutamine synthetase
H1I69_11300	COG0745	RESPONSE REGULATOR receiver
H1I69_11305	COG2205	protein histidine kinase activity
H1I69_11315	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1I69_11320	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1I69_11345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I69_11350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I69_11355	COG1960	acyl-CoA dehydrogenase activity
H1I69_11370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I69_11375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I69_11395	COG0583	DNA-binding transcription factor activity
H1I69_11410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I69_11420	COG3658	cytochrome
H1I69_11425	COG1215	transferase activity, transferring glycosyl groups
H1I69_11430	COG1649	PFAM Uncharacterised BCR, COG1649
H1I69_11430	COG0726	polysaccharide deacetylase
H1I69_11455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1I69_11460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1I69_11470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1I69_11495	COG0305	Participates in initiation and elongation during chromosome replication
H1I69_11500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1I69_11510	COG1305	Transglutaminase-like
H1I69_11520	COG2308	Evidence 4 Homologs of previously reported genes of
H1I69_11550	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H1I69_11555	COG0138	bifunctional purine biosynthesis protein purh
H1I69_11560	COG0151	Belongs to the GarS family
H1I69_11565	COG1464	Belongs to the NlpA lipoprotein family
H1I69_11570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I69_11575	COG2011	ABC-type metal ion transport system permease component
H1I69_11580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I69_11590	COG1301	dicarboxylic acid transport
H1I69_11625	COG1116	anion transmembrane transporter activity
H1I69_11630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I69_11640	COG0864	Transcriptional regulator
H1I69_11660	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I69_11665	COG0439	Biotin carboxylase
H1I69_11680	COG1063	alcohol dehydrogenase
H1I69_11690	COG1309	transcriptional regulator
H1I69_11710	COG0038	chloride channel
H1I69_11715	COG4770	biotin carboxylase activity
H1I69_11735	COG1914	H( )-stimulated, divalent metal cation uptake system
H1I69_11740	COG0583	DNA-binding transcription factor activity
H1I69_11790	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I69_11810	COG2814	Major facilitator Superfamily
H1I69_11820	COG1560	Kdo2-lipid A biosynthetic process
H1I69_11830	COG5006	permease, DMT superfamily
H1I69_11835	COG1522	sequence-specific DNA binding
H1I69_11850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1I69_11860	COG4122	O-methyltransferase activity
H1I69_11890	COG1538	Outer membrane efflux protein
H1I69_11895	COG1137	ATPase activity
H1I69_11900	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1I69_11910	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1I69_11915	COG0517	IMP dehydrogenase activity
H1I69_11915	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1I69_11950	COG2814	Major facilitator Superfamily
H1I69_11985	COG1278	Cold shock
H1I69_11990	COG1280	lysine exporter protein (LysE YggA)
H1I69_12020	COG1570	exodeoxyribonuclease VII activity
H1I69_12070	COG0583	DNA-binding transcription factor activity
H1I69_12075	COG4638	Rieske (2fe-2S)
H1I69_12080	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I69_12085	COG0543	2 iron, 2 sulfur cluster binding
H1I69_12085	COG0633	Ferredoxin
H1I69_12090	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_12095	COG3135	benzoate transporter
H1I69_12100	COG2814	Major facilitator Superfamily
H1I69_12115	COG1643	Atp-dependent helicase
H1I69_12120	COG0450	alkyl hydroperoxide reductase
H1I69_12130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1I69_12140	COG3634	alkyl hydroperoxide reductase activity
H1I69_12160	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1I69_12165	COG0625	glutathione transferase activity
H1I69_12175	COG2885	chlorophyll binding
H1I69_12210	COG0542	response to heat
H1I69_12225	COG1765	OsmC-like protein
H1I69_12240	COG0667	Aldo Keto reductase
H1I69_12255	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1I69_12265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1I69_12275	COG0527	aspartate kinase activity
H1I69_12285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1I69_12295	COG3038	cytochrome b561
H1I69_12300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1I69_12305	COG2252	PERMEase
H1I69_12315	COG2072	flavoprotein involved in K transport
H1I69_12340	COG1902	pentaerythritol trinitrate reductase activity
H1I69_12340	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I69_12350	COG5001	Diguanylate cyclase
H1I69_12350	COG3706	GGDEF domain
H1I69_12350	COG2203	Gaf domain
H1I69_12350	COG4251	negative regulation of phosphorylation
H1I69_12360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I69_12380	COG4172	Belongs to the ABC transporter superfamily
H1I69_12385	COG4239	(ABC) transporter, permease
H1I69_12390	COG4174	ABC transporter (Permease)
H1I69_12400	COG1388	LysM domain
H1I69_12400	COG0741	lytic transglycosylase activity
H1I69_12400	COG0741	lytic transglycosylase activity
H1I69_12400	COG1388	LysM domain
H1I69_12405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I69_12445	COG0583	DNA-binding transcription factor activity
H1I69_12450	COG1279	arginine transmembrane transporter activity
H1I69_12470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I69_12475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I69_12480	COG0006	proline dipeptidase activity
H1I69_12515	COG2194	sulfuric ester hydrolase activity
H1I69_12565	COG0739	heme binding
H1I69_12895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1I69_12920	COG3384	dioxygenase
H1I69_12930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I69_12935	COG2878	Part of a membrane complex involved in electron transport
H1I69_12940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1I69_12965	COG0768	penicillin binding
H1I69_12970	COG0742	ribosomal rna small subunit methyltransferase
H1I69_12985	COG0830	nickel cation binding
H1I69_13035	COG1253	flavin adenine dinucleotide binding
H1I69_13040	COG2851	Citrate transporter
H1I69_13095	COG1773	rubredoxin
H1I69_13100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I69_13110	COG0583	DNA-binding transcription factor activity
H1I69_13135	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1I69_13140	COG4181	ATPase activity
H1I69_13185	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1I69_13205	COG0306	phosphate transporter
H1I69_13215	COG3958	Transketolase
H1I69_13220	COG3959	Transketolase, thiamine diphosphate binding domain
H1I69_13225	COG2271	Major facilitator Superfamily
H1I69_13230	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_13235	COG0583	DNA-binding transcription factor activity
H1I69_13250	COG2223	nitrite transmembrane transporter activity
H1I69_13255	COG2207	Transcriptional regulator
H1I69_13260	COG2066	Belongs to the glutaminase family
H1I69_13265	COG0242	peptide deformylase activity
H1I69_13270	COG0477	Major facilitator Superfamily
H1I69_13280	COG0028	Belongs to the TPP enzyme family
H1I69_13295	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_13300	COG2267	carboxylic ester hydrolase activity
H1I69_13310	COG2271	Major facilitator Superfamily
H1I69_13315	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I69_13325	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_13345	COG1414	Transcriptional regulator
H1I69_13360	COG1024	Enoyl-CoA hydratase
H1I69_13370	COG1215	transferase activity, transferring glycosyl groups
H1I69_13375	COG1649	PFAM Uncharacterised BCR, COG1649
H1I69_13375	COG0726	polysaccharide deacetylase
H1I69_13385	COG4681	YaeQ
H1I69_13390	COG1301	dicarboxylic acid transport
H1I69_13395	COG0523	cobalamin synthesis protein
H1I69_13405	COG1607	acyl-coa hydrolase
H1I69_13415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I69_13420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I69_13425	COG1309	transcriptional regulator
H1I69_13450	COG2040	homocysteine
H1I69_13455	COG0531	amino acid
H1I69_13510	COG1595	DNA-templated transcription, initiation
H1I69_13520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I69_13525	COG0477	Major facilitator Superfamily
H1I69_13545	COG0084	hydrolase, TatD family'
H1I69_13580	COG0629	single-stranded DNA binding
H1I69_13635	COG0582	viral genome integration into host DNA
H1I69_13730	COG0592	DNA-directed DNA polymerase activity
H1I69_13770	COG2026	Addiction module toxin, RelE StbE family
H1I69_13910	COG1484	DNA-dependent DNA replication
H1I69_14000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I69_14070	COG0405	Gamma-glutamyltransferase
H1I69_14075	COG2814	Major facilitator Superfamily
H1I69_14085	COG2050	protein possibly involved in aromatic compounds catabolism
H1I69_14100	COG1090	epimerase
H1I69_14120	COG0420	3'-5' exonuclease activity
H1I69_14145	COG0735	belongs to the Fur family
H1I69_14150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1I69_14170	COG0121	glutamine amidotransferase
H1I69_14185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I69_14195	COG0210	DNA helicase
H1I69_14200	COG2885	chlorophyll binding
H1I69_14205	COG0204	Acyl-transferase
H1I69_14220	COG2894	cell division
H1I69_14245	COG1280	lysine exporter protein (LysE YggA)
H1I69_14250	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1I69_14250	COG1674	ftsk spoiiie
H1I69_14255	COG0492	ferredoxin-NADP+ reductase activity
H1I69_14260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H1I69_14270	COG0456	acetyltransferase
H1I69_14315	COG1981	membrane
H1I69_14330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1I69_14330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I69_14350	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_14360	COG0657	acetylesterase activity
H1I69_14370	COG0473	3-isopropylmalate dehydrogenase activity
H1I69_14375	COG0583	DNA-binding transcription factor activity
H1I69_14395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I69_14420	COG0564	pseudouridine synthase activity
H1I69_14430	COG0358	DNA primase activity
H1I69_14445	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H1I69_14475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I69_14505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1I69_14515	COG0352	thiamine-phosphate diphosphorylase activity
H1I69_14515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I69_14515	COG0351	phosphomethylpyrimidine kinase
H1I69_14520	COG1652	LysM domain
H1I69_14545	COG1399	metal-binding, possibly nucleic acid-binding protein
H1I69_14550	COG3101	peptidyl-lysine hydroxylation
H1I69_14555	COG0009	L-threonylcarbamoyladenylate synthase
H1I69_14560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H1I69_14565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H1I69_14580	COG4106	trans-aconitate 2-methyltransferase activity
H1I69_14595	COG0596	Alpha beta hydrolase
H1I69_14595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I69_14595	COG2226	methyltransferase
H1I69_14600	COG1877	trehalose-phosphatase activity
H1I69_14605	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1I69_14610	COG2223	nitrite transmembrane transporter activity
H1I69_14630	COG1196	nuclear chromosome segregation
H1I69_14640	COG0730	response to heat
H1I69_14655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1I69_14665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I69_14715	COG0489	protein tyrosine kinase activity
H1I69_14725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I69_14725	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I69_14755	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H1I69_14760	COG2081	HI0933 family
H1I69_14770	COG0668	transmembrane transport
H1I69_14790	COG0583	DNA-binding transcription factor activity
H1I69_14810	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1I69_14815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I69_14845	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H1I69_14885	COG0745	RESPONSE REGULATOR receiver
H1I69_14905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1I69_14915	COG2205	protein histidine kinase activity
H1I69_14985	COG4993	Dehydrogenase
H1I69_15010	COG0384	phenazine biosynthesis protein PhzF
H1I69_15030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I69_15045	COG0583	DNA-binding transcription factor activity
H1I69_15075	COG0583	DNA-binding transcription factor activity
H1I69_15090	COG0583	DNA-binding transcription factor activity
H1I69_15095	COG1053	succinate dehydrogenase
H1I69_15105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1I69_15110	COG2814	Major facilitator Superfamily
H1I69_15115	COG1960	acyl-CoA dehydrogenase activity
H1I69_15120	COG0583	DNA-binding transcription factor activity
H1I69_15125	COG1063	alcohol dehydrogenase
H1I69_15155	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1I69_15160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1I69_15165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I69_15180	COG3667	copper resistance
H1I69_15185	COG2132	Multicopper oxidase
H1I69_15195	COG0561	phosphatase activity
H1I69_15200	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1I69_15225	COG1214	PFAM Peptidase M22, glycoprotease
H1I69_15280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1I69_15290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1I69_15295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H1I69_15300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1I69_15360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I69_15370	COG1846	Transcriptional regulator
H1I69_15375	COG1764	response to oxidative stress
H1I69_15425	COG0037	tRNA processing
H1I69_15435	COG0248	Ppx GppA phosphatase
H1I69_15465	COG0072	phenylalanine-tRNA ligase activity
H1I69_15505	COG1238	metal cluster binding
H1I69_15510	COG0625	glutathione transferase activity
H1I69_15525	COG0318	PFAM AMP-dependent synthetase and ligase
H1I69_15530	COG3028	Belongs to the UPF0307 family
H1I69_15535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I69_15555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1I69_15560	COG0617	tRNA 3'-terminal CCA addition
H1I69_15565	COG1555	photosystem II stabilization
H1I69_15570	COG3956	TIGRFAM MazG family protein
H1I69_15580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I69_15600	COG0784	Response regulator, receiver
H1I69_15600	COG2205	protein histidine kinase activity
H1I69_15600	COG5002	protein histidine kinase activity
H1I69_15605	COG1024	Enoyl-CoA hydratase
H1I69_15610	COG2084	Dehydrogenase
H1I69_15615	COG3622	Belongs to the hyi family
H1I69_15645	COG0697	spore germination
H1I69_15655	COG2814	Major facilitator Superfamily
H1I69_15660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I69_15670	COG0583	DNA-binding transcription factor activity
H1I69_15680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1I69_15695	COG0084	hydrolase, TatD family'
H1I69_15710	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1I69_15740	COG0440	acetolactate synthase activity
H1I69_15745	COG0028	Belongs to the TPP enzyme family
H1I69_15770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I69_15775	COG1136	(ABC) transporter
H1I69_15775	COG0577	efflux transmembrane transporter activity
H1I69_15780	COG1538	Outer membrane efflux protein
H1I69_15795	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H1I69_15800	COG1162	GTPase activity
H1I69_15810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1I69_15830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1I69_15835	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_15875	COG2986	histidine ammonia-lyase
H1I69_15890	COG0318	PFAM AMP-dependent synthetase and ligase
H1I69_15900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I69_15945	COG1426	Protein conserved in bacteria
H1I69_15980	COG0793	Belongs to the peptidase S41A family
H1I69_15995	COG2267	carboxylic ester hydrolase activity
H1I69_16005	COG1012	belongs to the aldehyde dehydrogenase family
H1I69_16010	COG3265	gluconokinase activity
H1I69_16020	COG0800	Aldolase
H1I69_16035	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1I69_16040	COG0857	belongs to the CobB CobQ family
H1I69_16040	COG0280	phosphate acetyltransferase
H1I69_16045	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I69_16045	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I69_16065	COG0740	serine-type endopeptidase activity
H1I69_16075	COG4774	siderophore transport
H1I69_16085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1I69_16095	COG2813	Specifically methylates the guanine in position
H1I69_16095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I69_16195	COG0788	formyltetrahydrofolate deformylase activity
H1I69_16220	COG4651	solute:proton antiporter activity
H1I69_16220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I69_16240	COG0724	RNA recognition motif
H1I69_16245	COG0210	DNA helicase
H1I69_16270	COG1733	regulation of RNA biosynthetic process
H1I69_16280	COG2900	Belongs to the SlyX family
H1I69_16285	COG0488	(ABC) transporter
H1I69_16290	COG1280	lysine exporter protein (LysE YggA)
H1I69_16295	COG1560	Kdo2-lipid A biosynthetic process
H1I69_16305	COG1301	dicarboxylic acid transport
H1I69_16360	COG0473	3-isopropylmalate dehydrogenase activity
H1I69_16425	COG0583	DNA-binding transcription factor activity
H1I69_16435	COG0625	glutathione transferase activity
H1I69_16440	COG2378	regulation of single-species biofilm formation
H1I69_16445	COG0546	phosphoglycolate phosphatase activity
H1I69_16455	COG1530	ribonuclease E activity
H1I69_16460	COG0318	PFAM AMP-dependent synthetase and ligase
H1I69_16470	COG0583	DNA-binding transcription factor activity
H1I69_16475	COG4221	oxidoreductase activity
H1I69_16480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1I69_16490	COG0534	Mate efflux family protein
H1I69_16505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1I69_16545	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1I69_16550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I69_16565	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I69_16575	COG0644	oxidoreductase
H1I69_16575	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1I69_16580	COG0425	Belongs to the sulfur carrier protein TusA family
H1I69_16585	COG4535	Mg2 and Co2 transporter CorC
H1I69_16595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I69_16615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1I69_16620	COG0475	glutathione-regulated potassium exporter activity
H1I69_16620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I69_16625	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H1I69_16635	COG0484	heat shock protein binding
H1I69_16640	COG0789	Transcriptional regulator
H1I69_16645	COG0598	Magnesium transport protein CorA
H1I69_16660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I69_16665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I69_16670	COG1074	ATP-dependent DNA helicase activity
H1I69_16675	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1I69_16695	COG2226	methyltransferase
H1I69_16710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I69_16715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H1I69_16730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I69_16730	COG2111	Na H antiporter
H1I69_16735	COG1006	Multisubunit Na H antiporter MnhC subunit
H1I69_16740	COG0651	ATP synthesis coupled electron transport
H1I69_16745	COG1863	multisubunit Na H antiporter MnhE subunit
H1I69_16750	COG2212	antiporter activity
H1I69_16755	COG1320	monovalent cation:proton antiporter activity
H1I69_16770	COG0195	Participates in both transcription termination and antitermination
H1I69_16820	COG0237	dephospho-CoA kinase activity
H1I69_16830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I69_16845	COG0497	DNA recombination
H1I69_16855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1I69_16885	COG2169	Transcriptional regulator
H1I69_16885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I69_16890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1I69_16955	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1I69_16970	COG0326	Molecular chaperone. Has ATPase activity
H1I69_16985	COG2056	Na+-H+ antiporter family
H1I69_16990	COG0596	Alpha beta hydrolase
H1I69_17085	COG0546	phosphoglycolate phosphatase activity
H1I69_17090	COG1716	ATPase activity
H1I69_17135	COG0181	hydroxymethylbilane synthase activity
H1I69_17145	COG3275	phosphorelay sensor kinase activity
H1I69_17165	COG1538	Outer membrane efflux protein
H1I69_17170	COG0697	spore germination
H1I69_17195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I69_17200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1I69_17205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I69_17210	COG0772	Belongs to the SEDS family
H1I69_17235	COG4974	Belongs to the 'phage' integrase family
H1I69_17240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I69_17250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1I69_17260	COG2197	response regulator
H1I69_17275	COG0793	Belongs to the peptidase S41A family
H1I69_17280	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1I69_17285	COG0795	lipopolysaccharide-transporting ATPase activity
H1I69_17325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I69_17325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I69_17335	COG0004	ammonium transporteR
H1I69_17340	COG0347	Belongs to the P(II) protein family
H1I69_17350	COG0606	chelatase, subunit chli
H1I69_17420	COG1061	Type III restriction enzyme res subunit
H1I69_17435	COG0659	secondary active sulfate transmembrane transporter activity
H1I69_17440	COG0589	response to stress
H1I69_17470	COG0606	chelatase, subunit chli
H1I69_17485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I69_17500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1I69_17515	COG0318	PFAM AMP-dependent synthetase and ligase
H1I69_17525	COG0477	Major facilitator Superfamily
H1I69_17530	COG2860	membrane
H1I69_17540	COG1253	flavin adenine dinucleotide binding
H1I69_17550	COG2814	Major facilitator Superfamily
H1I69_17560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1I69_17595	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1I69_17605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1I69_17675	COG0758	DNA mediated transformation
H1I69_17685	COG0697	spore germination
H1I69_17690	COG1309	transcriptional regulator
H1I69_17705	COG0386	Belongs to the glutathione peroxidase family
H1I69_17780	COG1061	Type III restriction enzyme res subunit
H1I69_17790	COG1192	Involved in chromosome partitioning
H1I69_17795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I69_17820	COG1121	(ABC) transporter
H1I69_17825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1I69_17830	COG1280	lysine exporter protein (LysE YggA)
H1I69_17835	COG2837	iron assimilation
H1I69_17840	COG0281	malic enzyme
H1I69_17885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I69_17885	COG0519	Catalyzes the synthesis of GMP from XMP
H1I69_17890	COG4399	Belongs to the UPF0754 family
H1I69_17895	COG2259	Doxx family
H1I69_17900	COG0586	Pfam SNARE associated Golgi protein
H1I69_17915	COG1192	Involved in chromosome partitioning
H1I69_17925	COG0271	Belongs to the BolA IbaG family
H1I69_17940	COG0477	Major facilitator Superfamily
H1I69_17945	COG1024	Enoyl-CoA hydratase
H1I69_17950	COG1024	Enoyl-CoA hydratase
H1I69_17955	COG1960	acyl-CoA dehydrogenase activity
H1I69_17960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I69_17980	COG1113	amino acid transport
H1I69_17985	COG1113	amino acid transport
H1I69_17990	COG0251	oxidation-reduction process
H1I69_18030	COG0564	pseudouridine synthase activity
H1I69_18080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1I69_18095	COG1802	Transcriptional regulator
H1I69_18105	COG1448	Aminotransferase
H1I69_18110	COG0277	FAD linked oxidase domain protein
H1I69_18120	COG2186	Transcriptional regulator
H1I69_18130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I69_18135	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I69_18150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1I69_18160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1I69_18170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1I69_18175	COG0438	transferase activity, transferring glycosyl groups
H1I69_18195	COG1216	Glycosyl transferase, family 2
H1I69_18210	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1I69_18215	COG1596	polysaccharide export
H1I69_18240	COG0728	peptidoglycan biosynthetic process
H1I69_18245	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1I69_18305	COG0546	phosphoglycolate phosphatase activity
H1I69_18310	COG1028	Short-chain dehydrogenase reductase Sdr
H1I69_18330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I69_18340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I69_18345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I69_18350	COG1116	anion transmembrane transporter activity
H1I69_18355	COG1309	transcriptional regulator
H1I69_18360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1I69_18370	COG0196	riboflavin kinase activity
H1I69_18375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1I69_18385	COG1047	Peptidyl-prolyl cis-trans
H1I69_18425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1I69_18430	COG0657	acetylesterase activity
H1I69_18480	COG2951	lytic endotransglycosylase activity
H1I69_18485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1I69_18500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1I69_18510	COG0671	phosphoesterase, PA-phosphatase related
H1I69_18515	COG0861	Integral membrane protein TerC family
H1I69_18525	COG0754	glutathionylspermidine amidase activity
H1I69_18535	COG0402	S-adenosylhomocysteine deaminase activity
H1I69_18550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I69_18555	COG1230	cation diffusion facilitator family transporter
H1I69_18570	COG0706	membrane insertase activity