locus-tag	class	description
IVB58_00010	COG0592	DNA-directed DNA polymerase activity
IVB58_00020	COG0187	DNA topoisomerase II activity
IVB58_00030	COG0586	Pfam SNARE associated Golgi protein
IVB58_00035	COG0488	(ABC) transporter
IVB58_00060	COG0596	Alpha beta hydrolase
IVB58_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IVB58_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IVB58_00110	COG1047	Peptidyl-prolyl cis-trans
IVB58_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IVB58_00125	COG0196	riboflavin kinase activity
IVB58_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IVB58_00140	COG1309	transcriptional regulator
IVB58_00145	COG1116	anion transmembrane transporter activity
IVB58_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IVB58_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IVB58_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IVB58_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IVB58_00185	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_00190	COG0546	phosphoglycolate phosphatase activity
IVB58_00245	COG3023	N-Acetylmuramoyl-L-alanine amidase
IVB58_00250	COG0728	peptidoglycan biosynthetic process
IVB58_00280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IVB58_00290	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IVB58_00310	COG1216	Glycosyl transferase, family 2
IVB58_00310	COG0463	Glycosyl transferase, family 2
IVB58_00315	COG0438	transferase activity, transferring glycosyl groups
IVB58_00320	COG0438	transferase activity, transferring glycosyl groups
IVB58_00330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IVB58_00335	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IVB58_00350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IVB58_00360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IVB58_00370	COG2186	Transcriptional regulator
IVB58_00380	COG0277	FAD linked oxidase domain protein
IVB58_00385	COG1448	Aminotransferase
IVB58_00395	COG1802	Transcriptional regulator
IVB58_00410	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IVB58_00455	COG0564	pseudouridine synthase activity
IVB58_00495	COG0251	oxidation-reduction process
IVB58_00500	COG1113	amino acid transport
IVB58_00505	COG1113	amino acid transport
IVB58_00525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IVB58_00530	COG1960	acyl-CoA dehydrogenase activity
IVB58_00535	COG1024	Enoyl-CoA hydratase
IVB58_00540	COG1024	Enoyl-CoA hydratase
IVB58_00545	COG0477	Major facilitator Superfamily
IVB58_00550	COG3916	Acyl-homoserine-lactone synthase
IVB58_00560	COG2197	response regulator
IVB58_00570	COG1960	acyl-CoA dehydrogenase activity
IVB58_00575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IVB58_00575	COG3321	synthase
IVB58_00575	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IVB58_00575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IVB58_00595	COG2267	carboxylic ester hydrolase activity
IVB58_00610	COG0271	Belongs to the BolA IbaG family
IVB58_00620	COG1192	Involved in chromosome partitioning
IVB58_00635	COG0586	Pfam SNARE associated Golgi protein
IVB58_00640	COG2259	Doxx family
IVB58_00645	COG4399	Belongs to the UPF0754 family
IVB58_00650	COG0519	Catalyzes the synthesis of GMP from XMP
IVB58_00650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IVB58_00695	COG0281	malic enzyme
IVB58_00705	COG2837	iron assimilation
IVB58_00710	COG1280	lysine exporter protein (LysE YggA)
IVB58_00715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IVB58_00720	COG1121	(ABC) transporter
IVB58_00785	COG0386	Belongs to the glutathione peroxidase family
IVB58_00800	COG1309	transcriptional regulator
IVB58_00805	COG0697	spore germination
IVB58_00815	COG0758	DNA mediated transformation
IVB58_00850	COG1309	transcriptional regulator
IVB58_00885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IVB58_00895	COG0655	NAD(P)H dehydrogenase (quinone) activity
IVB58_00930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IVB58_00940	COG2814	Major facilitator Superfamily
IVB58_00950	COG1253	flavin adenine dinucleotide binding
IVB58_00955	COG3012	SEC-C Motif Domain Protein
IVB58_00960	COG2860	membrane
IVB58_00965	COG0477	Major facilitator Superfamily
IVB58_00975	COG0318	PFAM AMP-dependent synthetase and ligase
IVB58_00990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IVB58_01005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IVB58_01010	COG0235	Class ii aldolase
IVB58_01015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IVB58_01020	COG0606	chelatase, subunit chli
IVB58_01030	COG0347	Belongs to the P(II) protein family
IVB58_01035	COG0004	ammonium transporteR
IVB58_01045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IVB58_01045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IVB58_01085	COG0795	lipopolysaccharide-transporting ATPase activity
IVB58_01090	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IVB58_01095	COG0793	Belongs to the peptidase S41A family
IVB58_01110	COG2197	response regulator
IVB58_01120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IVB58_01130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IVB58_01135	COG4974	Belongs to the 'phage' integrase family
IVB58_01160	COG0772	Belongs to the SEDS family
IVB58_01165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IVB58_01170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IVB58_01175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IVB58_01200	COG0697	spore germination
IVB58_01205	COG1538	Outer membrane efflux protein
IVB58_01225	COG3275	phosphorelay sensor kinase activity
IVB58_01235	COG0181	hydroxymethylbilane synthase activity
IVB58_01280	COG1716	ATPase activity
IVB58_01285	COG0546	phosphoglycolate phosphatase activity
IVB58_01380	COG0596	Alpha beta hydrolase
IVB58_01385	COG2056	Na+-H+ antiporter family
IVB58_01400	COG0326	Molecular chaperone. Has ATPase activity
IVB58_01415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IVB58_01480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IVB58_01485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IVB58_01485	COG2169	Transcriptional regulator
IVB58_01515	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IVB58_01525	COG0497	DNA recombination
IVB58_01540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IVB58_01550	COG0237	dephospho-CoA kinase activity
IVB58_01600	COG0195	Participates in both transcription termination and antitermination
IVB58_01615	COG1320	monovalent cation:proton antiporter activity
IVB58_01620	COG2212	antiporter activity
IVB58_01625	COG1863	multisubunit Na H antiporter MnhE subunit
IVB58_01630	COG0651	ATP synthesis coupled electron transport
IVB58_01635	COG1006	Multisubunit Na H antiporter MnhC subunit
IVB58_01640	COG2111	Na H antiporter
IVB58_01640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IVB58_01655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IVB58_01685	COG2226	methyltransferase
IVB58_01705	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IVB58_01710	COG1074	ATP-dependent DNA helicase activity
IVB58_01715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IVB58_01720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IVB58_01735	COG0598	Magnesium transport protein CorA
IVB58_01740	COG0789	Transcriptional regulator
IVB58_01745	COG0484	heat shock protein binding
IVB58_01760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IVB58_01760	COG0475	glutathione-regulated potassium exporter activity
IVB58_01765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IVB58_01785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IVB58_01795	COG4535	Mg2 and Co2 transporter CorC
IVB58_01800	COG0425	Belongs to the sulfur carrier protein TusA family
IVB58_01810	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IVB58_01810	COG0644	oxidoreductase
IVB58_01820	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IVB58_01835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IVB58_01840	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IVB58_01850	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IVB58_01850	COG0493	'glutamate synthase
IVB58_01875	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IVB58_01890	COG0534	Mate efflux family protein
IVB58_01900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IVB58_01905	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_01910	COG0583	DNA-binding transcription factor activity
IVB58_01925	COG0318	PFAM AMP-dependent synthetase and ligase
IVB58_01930	COG1530	ribonuclease E activity
IVB58_01940	COG0546	phosphoglycolate phosphatase activity
IVB58_01945	COG2378	regulation of single-species biofilm formation
IVB58_01950	COG0625	glutathione transferase activity
IVB58_01960	COG0583	DNA-binding transcription factor activity
IVB58_02015	COG0473	3-isopropylmalate dehydrogenase activity
IVB58_02070	COG1301	dicarboxylic acid transport
IVB58_02080	COG1560	Kdo2-lipid A biosynthetic process
IVB58_02085	COG1280	lysine exporter protein (LysE YggA)
IVB58_02095	COG0488	(ABC) transporter
IVB58_02100	COG2900	Belongs to the SlyX family
IVB58_02110	COG1733	regulation of RNA biosynthetic process
IVB58_02135	COG0210	DNA helicase
IVB58_02140	COG0724	RNA recognition motif
IVB58_02160	COG4651	solute:proton antiporter activity
IVB58_02160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IVB58_02185	COG0788	formyltetrahydrofolate deformylase activity
IVB58_02285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IVB58_02285	COG2813	Specifically methylates the guanine in position
IVB58_02295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IVB58_02305	COG4774	siderophore transport
IVB58_02315	COG0740	serine-type endopeptidase activity
IVB58_02335	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IVB58_02335	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IVB58_02340	COG0280	phosphate acetyltransferase
IVB58_02340	COG0857	belongs to the CobB CobQ family
IVB58_02345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IVB58_02355	COG0800	Aldolase
IVB58_02365	COG3265	gluconokinase activity
IVB58_02370	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_02380	COG2267	carboxylic ester hydrolase activity
IVB58_02395	COG0793	Belongs to the peptidase S41A family
IVB58_02430	COG1426	Protein conserved in bacteria
IVB58_02460	COG2091	lysine biosynthetic process via aminoadipic acid
IVB58_02470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IVB58_02480	COG1162	GTPase activity
IVB58_02485	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IVB58_02500	COG1538	Outer membrane efflux protein
IVB58_02505	COG1136	(ABC) transporter
IVB58_02505	COG0577	efflux transmembrane transporter activity
IVB58_02510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IVB58_02535	COG0028	Belongs to the TPP enzyme family
IVB58_02540	COG0440	acetolactate synthase activity
IVB58_02655	COG4221	oxidoreductase activity
IVB58_02660	COG0583	DNA-binding transcription factor activity
IVB58_02665	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IVB58_02670	COG0604	alcohol dehydrogenase
IVB58_02670	COG3321	synthase
IVB58_02685	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IVB58_02700	COG1979	alcohol dehydrogenase
IVB58_02710	COG1902	pentaerythritol trinitrate reductase activity
IVB58_02720	COG1309	transcriptional regulator
IVB58_02725	COG2130	NADP-dependent
IVB58_02755	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IVB58_02770	COG0084	hydrolase, TatD family'
IVB58_02780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IVB58_02790	COG0583	DNA-binding transcription factor activity
IVB58_02800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IVB58_02805	COG2814	Major facilitator Superfamily
IVB58_02815	COG0697	spore germination
IVB58_02845	COG3622	Belongs to the hyi family
IVB58_02850	COG2084	Dehydrogenase
IVB58_02855	COG1024	Enoyl-CoA hydratase
IVB58_02860	COG5002	protein histidine kinase activity
IVB58_02860	COG0784	Response regulator, receiver
IVB58_02860	COG2205	protein histidine kinase activity
IVB58_02880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IVB58_02890	COG3956	TIGRFAM MazG family protein
IVB58_02895	COG1555	photosystem II stabilization
IVB58_02900	COG0617	tRNA 3'-terminal CCA addition
IVB58_02905	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IVB58_02925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IVB58_02930	COG3028	Belongs to the UPF0307 family
IVB58_02935	COG0318	PFAM AMP-dependent synthetase and ligase
IVB58_02950	COG0625	glutathione transferase activity
IVB58_02955	COG1238	metal cluster binding
IVB58_02995	COG0072	phenylalanine-tRNA ligase activity
IVB58_03025	COG0248	Ppx GppA phosphatase
IVB58_03035	COG0037	tRNA processing
IVB58_03075	COG1764	response to oxidative stress
IVB58_03080	COG1846	Transcriptional regulator
IVB58_03090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IVB58_03150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IVB58_03155	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IVB58_03160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IVB58_03220	COG1214	PFAM Peptidase M22, glycoprotease
IVB58_03245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IVB58_03250	COG0561	phosphatase activity
IVB58_03260	COG2132	Multicopper oxidase
IVB58_03280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IVB58_03285	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IVB58_03290	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IVB58_03320	COG1063	alcohol dehydrogenase
IVB58_03325	COG0583	DNA-binding transcription factor activity
IVB58_03330	COG1960	acyl-CoA dehydrogenase activity
IVB58_03335	COG2814	Major facilitator Superfamily
IVB58_03340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IVB58_03345	COG1309	transcriptional regulator
IVB58_03360	COG1053	succinate dehydrogenase
IVB58_03365	COG0583	DNA-binding transcription factor activity
IVB58_03380	COG0583	DNA-binding transcription factor activity
IVB58_03390	COG0583	DNA-binding transcription factor activity
IVB58_03405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IVB58_03415	COG5290	Psort location Cytoplasmic, score
IVB58_03435	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IVB58_03455	COG0745	RESPONSE REGULATOR receiver
IVB58_03495	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IVB58_03525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IVB58_03530	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IVB58_03555	COG0583	DNA-binding transcription factor activity
IVB58_03575	COG0668	transmembrane transport
IVB58_03585	COG2081	HI0933 family
IVB58_03590	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IVB58_03620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IVB58_03620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IVB58_03630	COG0489	protein tyrosine kinase activity
IVB58_03690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IVB58_03705	COG0730	response to heat
IVB58_03715	COG1196	nuclear chromosome segregation
IVB58_03735	COG2223	nitrite transmembrane transporter activity
IVB58_03740	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IVB58_03745	COG1877	trehalose-phosphatase activity
IVB58_03750	COG0596	Alpha beta hydrolase
IVB58_03750	COG2226	methyltransferase
IVB58_03750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IVB58_03765	COG4106	trans-aconitate 2-methyltransferase activity
IVB58_03780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IVB58_03785	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IVB58_03790	COG0009	L-threonylcarbamoyladenylate synthase
IVB58_03795	COG3101	peptidyl-lysine hydroxylation
IVB58_03800	COG1399	metal-binding, possibly nucleic acid-binding protein
IVB58_03825	COG1652	LysM domain
IVB58_03830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IVB58_03830	COG0352	thiamine-phosphate diphosphorylase activity
IVB58_03830	COG0351	phosphomethylpyrimidine kinase
IVB58_03840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IVB58_03870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IVB58_03900	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IVB58_03915	COG0358	DNA primase activity
IVB58_03925	COG0564	pseudouridine synthase activity
IVB58_03950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IVB58_03970	COG0583	DNA-binding transcription factor activity
IVB58_03975	COG0473	3-isopropylmalate dehydrogenase activity
IVB58_03985	COG0657	acetylesterase activity
IVB58_03995	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_04015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IVB58_04015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IVB58_04030	COG1981	membrane
IVB58_04075	COG0456	acetyltransferase
IVB58_04085	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IVB58_04090	COG0492	ferredoxin-NADP+ reductase activity
IVB58_04095	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IVB58_04095	COG1674	ftsk spoiiie
IVB58_04115	COG2894	cell division
IVB58_04130	COG0204	Acyl-transferase
IVB58_04135	COG2885	chlorophyll binding
IVB58_04140	COG0210	DNA helicase
IVB58_04150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IVB58_04185	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IVB58_04190	COG0735	belongs to the Fur family
IVB58_04215	COG0420	3'-5' exonuclease activity
IVB58_04235	COG1090	epimerase
IVB58_04250	COG2050	protein possibly involved in aromatic compounds catabolism
IVB58_04260	COG2814	Major facilitator Superfamily
IVB58_04265	COG0405	Gamma-glutamyltransferase
IVB58_04275	COG0582	viral genome integration into host DNA
IVB58_04320	COG1401	restriction endodeoxyribonuclease activity
IVB58_04330	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IVB58_04350	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IVB58_04375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IVB58_04395	COG3177	Filamentation induced by cAMP protein fic
IVB58_04440	COG0477	Major facilitator Superfamily
IVB58_04445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IVB58_04470	COG0531	amino acid
IVB58_04475	COG2040	homocysteine
IVB58_04500	COG1309	transcriptional regulator
IVB58_04505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IVB58_04510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IVB58_04520	COG1607	acyl-coa hydrolase
IVB58_04530	COG0523	cobalamin synthesis protein
IVB58_04540	COG4681	YaeQ
IVB58_04550	COG1649	PFAM Uncharacterised BCR, COG1649
IVB58_04550	COG0726	polysaccharide deacetylase
IVB58_04555	COG1215	transferase activity, transferring glycosyl groups
IVB58_04565	COG1024	Enoyl-CoA hydratase
IVB58_04580	COG1414	Transcriptional regulator
IVB58_04600	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_04615	COG2271	Major facilitator Superfamily
IVB58_04625	COG2267	carboxylic ester hydrolase activity
IVB58_04630	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_04645	COG0028	Belongs to the TPP enzyme family
IVB58_04655	COG0477	Major facilitator Superfamily
IVB58_04660	COG0242	peptide deformylase activity
IVB58_04665	COG2066	Belongs to the glutaminase family
IVB58_04670	COG2207	Transcriptional regulator
IVB58_04675	COG2223	nitrite transmembrane transporter activity
IVB58_04690	COG0583	DNA-binding transcription factor activity
IVB58_04695	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_04700	COG2271	Major facilitator Superfamily
IVB58_04705	COG3959	Transketolase, thiamine diphosphate binding domain
IVB58_04710	COG3958	Transketolase
IVB58_04720	COG0306	phosphate transporter
IVB58_04740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IVB58_04785	COG4181	ATPase activity
IVB58_04790	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IVB58_04820	COG0583	DNA-binding transcription factor activity
IVB58_04830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IVB58_04835	COG1773	rubredoxin
IVB58_04885	COG2851	Citrate transporter
IVB58_04890	COG1253	flavin adenine dinucleotide binding
IVB58_04930	COG0804	urea catabolic process
IVB58_04940	COG0830	nickel cation binding
IVB58_04955	COG0742	ribosomal rna small subunit methyltransferase
IVB58_04960	COG0768	penicillin binding
IVB58_04985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IVB58_04990	COG2878	Part of a membrane complex involved in electron transport
IVB58_04995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IVB58_05005	COG3384	dioxygenase
IVB58_05040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IVB58_05080	COG0006	proline dipeptidase activity
IVB58_05085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IVB58_05090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IVB58_05110	COG1279	arginine transmembrane transporter activity
IVB58_05115	COG0583	DNA-binding transcription factor activity
IVB58_05155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IVB58_05160	COG0741	lytic transglycosylase activity
IVB58_05160	COG0741	lytic transglycosylase activity
IVB58_05160	COG1388	LysM domain
IVB58_05160	COG1388	LysM domain
IVB58_05170	COG4174	ABC transporter (Permease)
IVB58_05175	COG4239	(ABC) transporter, permease
IVB58_05180	COG4172	Belongs to the ABC transporter superfamily
IVB58_05200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IVB58_05210	COG2203	Gaf domain
IVB58_05210	COG5001	Diguanylate cyclase
IVB58_05210	COG3706	GGDEF domain
IVB58_05210	COG4251	negative regulation of phosphorylation
IVB58_05220	COG1902	pentaerythritol trinitrate reductase activity
IVB58_05220	COG0446	pyridine nucleotide-disulphide oxidoreductase
IVB58_05280	COG3209	COG3209 Rhs family protein
IVB58_05315	COG1113	amino acid transport
IVB58_05325	COG0531	amino acid
IVB58_05345	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_05365	COG1113	amino acid transport
IVB58_05380	COG0697	spore germination
IVB58_05385	COG2721	sulfolactate sulfo-lyase activity
IVB58_05390	COG2271	Major facilitator Superfamily
IVB58_05395	COG4948	Mandelate Racemase Muconate Lactonizing
IVB58_05405	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_05410	COG2186	Transcriptional regulator
IVB58_05435	COG1960	acyl-CoA dehydrogenase activity
IVB58_05445	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_05450	COG1024	Enoyl-CoA hydratase
IVB58_05455	COG2814	Major facilitator Superfamily
IVB58_05470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IVB58_05515	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IVB58_05520	COG2072	flavoprotein involved in K transport
IVB58_05525	COG0300	oxidoreductase activity
IVB58_05535	COG1309	transcriptional regulator
IVB58_05540	COG1741	Belongs to the pirin family
IVB58_05555	COG2072	flavoprotein involved in K transport
IVB58_05565	COG2252	PERMEase
IVB58_05570	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IVB58_05575	COG3038	cytochrome b561
IVB58_05585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IVB58_05595	COG0527	aspartate kinase activity
IVB58_05825	COG1598	PFAM Uncharacterised protein family UPF0150
IVB58_05945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IVB58_05955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IVB58_05970	COG0667	Aldo Keto reductase
IVB58_05985	COG1765	OsmC-like protein
IVB58_06000	COG0542	response to heat
IVB58_06035	COG2885	chlorophyll binding
IVB58_06045	COG0625	glutathione transferase activity
IVB58_06050	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IVB58_06070	COG3634	alkyl hydroperoxide reductase activity
IVB58_06080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IVB58_06090	COG0450	alkyl hydroperoxide reductase
IVB58_06095	COG1643	Atp-dependent helicase
IVB58_06110	COG2814	Major facilitator Superfamily
IVB58_06115	COG3135	benzoate transporter
IVB58_06120	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_06125	COG0543	2 iron, 2 sulfur cluster binding
IVB58_06125	COG0633	Ferredoxin
IVB58_06130	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IVB58_06135	COG4638	Rieske (2fe-2S)
IVB58_06140	COG0583	DNA-binding transcription factor activity
IVB58_06190	COG1570	exodeoxyribonuclease VII activity
IVB58_06220	COG1280	lysine exporter protein (LysE YggA)
IVB58_06225	COG1278	Cold shock
IVB58_06260	COG2814	Major facilitator Superfamily
IVB58_06345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IVB58_06350	COG4197	protein conserved in bacteria, prophage-related
IVB58_06445	COG5410	chromosome segregation
IVB58_06450	COG3567	Phage-associated protein, HI1409 family
IVB58_06475	COG3566	protein conserved in bacteria
IVB58_06555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IVB58_06605	COG0517	IMP dehydrogenase activity
IVB58_06605	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IVB58_06610	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IVB58_06620	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IVB58_06625	COG1137	ATPase activity
IVB58_06630	COG1538	Outer membrane efflux protein
IVB58_06660	COG4122	O-methyltransferase activity
IVB58_06670	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IVB58_06685	COG1522	sequence-specific DNA binding
IVB58_06690	COG5006	permease, DMT superfamily
IVB58_06700	COG1560	Kdo2-lipid A biosynthetic process
IVB58_06740	COG1250	3-hydroxyacyl-CoA dehydrogenase
IVB58_06775	COG1914	H( )-stimulated, divalent metal cation uptake system
IVB58_06795	COG4770	biotin carboxylase activity
IVB58_06800	COG0038	chloride channel
IVB58_06825	COG1309	transcriptional regulator
IVB58_06855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IVB58_06900	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_06905	COG0531	amino acid
IVB58_06910	COG1760	l-serine dehydratase
IVB58_06915	COG2030	dehydratase
IVB58_06915	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_06920	COG3396	Phenylacetate-CoA oxygenase
IVB58_06925	COG3460	Phenylacetate-CoA oxygenase
IVB58_06930	COG3396	Phenylacetate-CoA oxygenase
IVB58_06935	COG2151	metal-sulfur cluster biosynthetic enzyme
IVB58_06940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IVB58_06945	COG1024	Enoyl-CoA hydratase
IVB58_06950	COG1024	Enoyl-CoA hydratase
IVB58_06955	COG1250	3-hydroxyacyl-CoA dehydrogenase
IVB58_06960	COG0183	Belongs to the thiolase family
IVB58_06965	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IVB58_06970	COG3327	negative regulation of DNA-templated transcription, initiation
IVB58_06980	COG2050	protein possibly involved in aromatic compounds catabolism
IVB58_07020	COG2207	Transcriptional regulator
IVB58_07035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IVB58_07040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IVB58_07045	COG2271	Major facilitator Superfamily
IVB58_07050	COG0753	catalase activity
IVB58_07055	COG3038	cytochrome b561
IVB58_07060	COG0583	DNA-binding transcription factor activity
IVB58_07070	COG1414	Transcriptional regulator
IVB58_07075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IVB58_07085	COG1840	ABC-type Fe3 transport system, periplasmic component
IVB58_07090	COG3842	ATPase activity
IVB58_07105	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IVB58_07110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IVB58_07115	COG2814	Major facilitator Superfamily
IVB58_07120	COG1960	acyl-CoA dehydrogenase activity
IVB58_07135	COG1024	Enoyl-CoA hydratase
IVB58_07145	COG2814	Major facilitator Superfamily
IVB58_07155	COG0183	Belongs to the thiolase family
IVB58_07160	COG1250	3-hydroxyacyl-CoA dehydrogenase
IVB58_07165	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_07170	COG1024	Enoyl-CoA hydratase
IVB58_07175	COG1960	acyl-CoA dehydrogenase activity
IVB58_07180	COG2814	Major facilitator Superfamily
IVB58_07185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IVB58_07190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IVB58_07200	COG2814	Major facilitator Superfamily
IVB58_07210	COG1960	acyl-CoA dehydrogenase activity
IVB58_07225	COG0583	DNA-binding transcription factor activity
IVB58_07235	COG4770	biotin carboxylase activity
IVB58_07240	COG1024	Enoyl-CoA hydratase
IVB58_07245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IVB58_07250	COG1960	acyl-CoA dehydrogenase activity
IVB58_07255	COG1309	transcriptional regulator
IVB58_07260	COG0318	PFAM AMP-dependent synthetase and ligase
IVB58_07280	COG0583	DNA-binding transcription factor activity
IVB58_07330	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_07350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IVB58_07370	COG2205	protein histidine kinase activity
IVB58_07370	COG0784	Response regulator, receiver
IVB58_07390	COG0765	amino acid transport
IVB58_07395	COG0765	amino acid transport
IVB58_07400	COG1126	abc transporter atp-binding protein
IVB58_07405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IVB58_07410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IVB58_07425	COG1280	lysine exporter protein (LysE YggA)
IVB58_07430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IVB58_07435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IVB58_07440	COG1045	serine acetyltransferase
IVB58_07455	COG0583	DNA-binding transcription factor activity
IVB58_07460	COG0625	glutathione transferase activity
IVB58_07465	COG0625	glutathione transferase activity
IVB58_07470	COG0583	DNA-binding transcription factor activity
IVB58_07480	COG1346	cytolysis
IVB58_07500	COG2814	Major facilitator Superfamily
IVB58_07510	COG0583	DNA-binding transcription factor activity
IVB58_07520	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IVB58_07525	COG3052	prosthetic group binding
IVB58_07545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IVB58_07565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IVB58_07575	COG1294	oxidase, subunit
IVB58_07580	COG1271	oxidase subunit
IVB58_07600	COG0477	Major facilitator Superfamily
IVB58_07610	COG4521	taurine ABC transporter
IVB58_07615	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IVB58_07620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IVB58_07625	COG2175	clavaminate synthase activity
IVB58_07635	COG1953	Uracil, thiamine, allantoin
IVB58_07645	COG0583	DNA-binding transcription factor activity
IVB58_07655	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IVB58_07670	COG0640	Transcriptional regulator
IVB58_07675	COG0798	PFAM Bile acid sodium symporter
IVB58_07680	COG0583	DNA-binding transcription factor activity
IVB58_07695	COG3634	alkyl hydroperoxide reductase activity
IVB58_07730	COG1301	dicarboxylic acid transport
IVB58_07735	COG0436	Aminotransferase
IVB58_07745	COG0386	Belongs to the glutathione peroxidase family
IVB58_07785	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IVB58_07810	COG0012	GTP binding
IVB58_07815	COG2011	ABC-type metal ion transport system permease component
IVB58_07820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IVB58_07830	COG1464	Belongs to the NlpA lipoprotein family
IVB58_07860	COG0765	amino acid transport
IVB58_07865	COG0765	amino acid transport
IVB58_07870	COG1126	abc transporter atp-binding protein
IVB58_07880	COG1522	sequence-specific DNA binding
IVB58_07895	COG1309	transcriptional regulator
IVB58_07905	COG0582	viral genome integration into host DNA
IVB58_07910	COG0784	Response regulator, receiver
IVB58_07910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IVB58_07975	COG0583	DNA-binding transcription factor activity
IVB58_07985	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IVB58_07995	COG0697	spore germination
IVB58_08020	COG3121	Chaperone
IVB58_08025	COG3539	Fimbrial protein
IVB58_08050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IVB58_08050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IVB58_08095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IVB58_08105	COG2353	YceI-like domain
IVB58_08115	COG3698	Phosphodiester glycosidase
IVB58_08130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IVB58_08135	COG0506	proline dehydrogenase activity
IVB58_08135	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IVB58_08135	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IVB58_08145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IVB58_08150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IVB58_08170	COG1132	(ABC) transporter
IVB58_08175	COG3122	Protein conserved in bacteria
IVB58_08180	COG3619	membrane
IVB58_08190	COG0640	Transcriptional regulator
IVB58_08200	COG2850	peptidyl-arginine hydroxylation
IVB58_08205	COG0424	maF-like protein
IVB58_08225	COG0191	fructose-bisphosphate aldolase activity
IVB58_08230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IVB58_08245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IVB58_08255	COG1192	Involved in chromosome partitioning
IVB58_08260	COG1475	DNA binding
IVB58_08265	COG0811	peptide transport
IVB58_08275	COG1132	(ABC) transporter
IVB58_08280	COG1663	tetraacyldisaccharide 4'-kinase activity
IVB58_08300	COG0084	hydrolase, TatD family'
IVB58_08365	COG0776	regulation of translation
IVB58_08395	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IVB58_08400	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IVB58_08450	COG0339	signal peptide processing
IVB58_08460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IVB58_08495	COG0702	epimerase
IVB58_08500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IVB58_08520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IVB58_08550	COG0316	Belongs to the HesB IscA family
IVB58_08555	COG0822	iron-sulfur transferase activity
IVB58_08580	COG0776	regulation of translation
IVB58_08585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IVB58_08590	COG2207	Transcriptional regulator
IVB58_08595	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IVB58_08600	COG1960	acyl-CoA dehydrogenase activity
IVB58_08605	COG1960	acyl-CoA dehydrogenase activity
IVB58_08620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IVB58_08640	COG4264	IucA IucC family
IVB58_08645	COG4264	IucA IucC family
IVB58_08655	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IVB58_08685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IVB58_08700	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IVB58_08705	COG0406	alpha-ribazole phosphatase activity
IVB58_08720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IVB58_08725	COG0730	response to heat
IVB58_08745	COG4773	Receptor
IVB58_08750	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IVB58_08765	COG1131	(ABC) transporter
IVB58_08770	COG0842	Transport permease protein
IVB58_08775	COG0842	Transport permease protein
IVB58_08830	COG2226	methyltransferase
IVB58_08855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IVB58_08890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IVB58_08900	COG0133	tryptophan synthase activity
IVB58_08915	COG3706	GGDEF domain
IVB58_08930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IVB58_08935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IVB58_08940	COG0022	dehydrogenase e1 component
IVB58_08945	COG0508	dehydrogenase complex catalyzes the overall conversion of
IVB58_08950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IVB58_08960	COG1063	alcohol dehydrogenase
IVB58_08965	COG3781	membrane
IVB58_08985	COG0730	response to heat
IVB58_09000	COG2207	Transcriptional regulator
IVB58_09000	COG3708	Transcriptional regulator
IVB58_09005	COG1733	regulation of RNA biosynthetic process
IVB58_09010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IVB58_09020	COG2188	Transcriptional regulator
IVB58_09035	COG4521	taurine ABC transporter
IVB58_09040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IVB58_09060	COG0477	Major facilitator Superfamily
IVB58_09070	COG1027	Aspartate ammonia-lyase
IVB58_09085	COG0583	DNA-binding transcription factor activity
IVB58_09090	COG0583	DNA-binding transcription factor activity
IVB58_09095	COG0183	Belongs to the thiolase family
IVB58_09100	COG2031	fatty acid transporter
IVB58_09115	COG0583	DNA-binding transcription factor activity
IVB58_09135	COG1309	transcriptional regulator
IVB58_09145	COG2610	gluconate transmembrane transporter activity
IVB58_09150	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_09155	COG2207	Transcriptional regulator
IVB58_09170	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_09180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IVB58_09195	COG0543	2 iron, 2 sulfur cluster binding
IVB58_09195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IVB58_09200	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IVB58_09215	COG0725	ABC transporter, periplasmic molybdate-binding protein
IVB58_09220	COG4149	molybdate abc transporter
IVB58_09225	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IVB58_09230	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_09235	COG1535	isochorismatase
IVB58_09235	COG3433	isochorismatase activity
IVB58_09295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IVB58_09310	COG0753	catalase activity
IVB58_09320	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IVB58_09345	COG3539	Fimbrial protein
IVB58_09360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IVB58_09365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IVB58_09370	COG0745	RESPONSE REGULATOR receiver
IVB58_09375	COG2205	protein histidine kinase activity
IVB58_09385	COG2207	Transcriptional regulator
IVB58_09400	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_09425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IVB58_09460	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IVB58_09510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IVB58_09530	COG1120	ATPase activity
IVB58_09535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IVB58_09545	COG1064	alcohol dehydrogenase
IVB58_09560	COG2207	Transcriptional regulator
IVB58_09565	COG2084	Dehydrogenase
IVB58_09575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IVB58_09580	COG0583	DNA-binding transcription factor activity
IVB58_09590	COG0129	dihydroxy-acid dehydratase activity
IVB58_09595	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_09610	COG1566	PFAM secretion protein HlyD family protein
IVB58_09625	COG0583	DNA-binding transcription factor activity
IVB58_09640	COG2188	Transcriptional regulator
IVB58_09675	COG4191	Histidine kinase
IVB58_09690	COG1473	amidohydrolase
IVB58_09700	COG0475	glutathione-regulated potassium exporter activity
IVB58_09700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IVB58_09710	COG0583	DNA-binding transcription factor activity
IVB58_09715	COG1335	isochorismatase
IVB58_09725	COG1309	transcriptional regulator
IVB58_09765	COG1902	pentaerythritol trinitrate reductase activity
IVB58_09765	COG0446	pyridine nucleotide-disulphide oxidoreductase
IVB58_09780	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_09800	COG2186	Transcriptional regulator
IVB58_09810	COG0583	DNA-binding transcription factor activity
IVB58_09815	COG4948	Mandelate Racemase Muconate Lactonizing
IVB58_09820	COG4829	muconolactone delta-isomerase
IVB58_09830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IVB58_09835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IVB58_09840	COG0183	Belongs to the thiolase family
IVB58_09845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IVB58_09855	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_09865	COG3733	amine oxidase
IVB58_09875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IVB58_09885	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_09895	COG4638	Rieske (2fe-2S)
IVB58_09915	COG0154	amidase activity
IVB58_09925	COG2814	Major facilitator Superfamily
IVB58_09950	COG1960	acyl-CoA dehydrogenase activity
IVB58_09955	COG0583	DNA-binding transcription factor activity
IVB58_09960	COG1414	Transcriptional regulator
IVB58_09975	COG2391	methyltransferase activity
IVB58_09985	COG4993	Dehydrogenase
IVB58_09990	COG3659	wide pore channel activity
IVB58_09995	COG3420	alginic acid biosynthetic process
IVB58_10000	COG0710	3-dehydroquinate dehydratase activity
IVB58_10005	COG3485	protocatechuate 3,4-dioxygenase
IVB58_10010	COG3485	protocatechuate 3,4-dioxygenase
IVB58_10015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IVB58_10020	COG2271	Major facilitator Superfamily
IVB58_10025	COG0596	Alpha beta hydrolase
IVB58_10030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IVB58_10035	COG0183	Belongs to the thiolase family
IVB58_10040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IVB58_10045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IVB58_10055	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IVB58_10060	COG2323	membrane
IVB58_10105	COG0446	pyridine nucleotide-disulphide oxidoreductase
IVB58_10105	COG1902	pentaerythritol trinitrate reductase activity
IVB58_10120	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IVB58_10130	COG0542	response to heat
IVB58_10135	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IVB58_10165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IVB58_10170	COG0569	domain protein
IVB58_10175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IVB58_10190	COG4774	siderophore transport
IVB58_10195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IVB58_10205	COG1585	Membrane protein implicated in regulation of membrane protease activity
IVB58_10220	COG1294	oxidase, subunit
IVB58_10225	COG4890	Cyd operon protein YbgT
IVB58_10240	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IVB58_10250	COG0552	protein localization to endoplasmic reticulum
IVB58_10275	COG0517	IMP dehydrogenase activity
IVB58_10275	COG0516	GMP reductase activity
IVB58_10280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IVB58_10285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IVB58_10295	COG0583	DNA-binding transcription factor activity
IVB58_10300	COG0024	Methionine aminopeptidase
IVB58_10330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IVB58_10330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IVB58_10335	COG1105	Belongs to the carbohydrate kinase PfkB family
IVB58_10340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IVB58_10340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IVB58_10340	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IVB58_10355	COG5001	Diguanylate cyclase
IVB58_10355	COG3300	MHYT domain
IVB58_10370	COG2135	peptidase activity
IVB58_10375	COG0659	secondary active sulfate transmembrane transporter activity
IVB58_10390	COG1113	amino acid transport
IVB58_10400	COG1522	sequence-specific DNA binding
IVB58_10425	COG1011	Hydrolase
IVB58_10430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IVB58_10440	COG2137	regulation of response to DNA damage stimulus
IVB58_10455	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IVB58_10475	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IVB58_10490	COG0575	Belongs to the CDS family
IVB58_10495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IVB58_10520	COG3852	Histidine kinase
IVB58_10525	COG2204	response regulator
IVB58_10580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IVB58_10585	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IVB58_10605	COG0697	spore germination
IVB58_10610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IVB58_10620	COG0303	'Molybdopterin
IVB58_10625	COG0315	cyclic pyranopterin monophosphate synthase activity
IVB58_10625	COG0521	Mo-molybdopterin cofactor biosynthetic process
IVB58_10640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IVB58_10645	COG0243	molybdopterin cofactor binding
IVB58_10655	COG0243	molybdopterin cofactor binding
IVB58_10660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IVB58_10665	COG2146	nitrite reductase [NAD(P)H] activity
IVB58_10665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IVB58_10675	COG0745	RESPONSE REGULATOR receiver
IVB58_10680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IVB58_10680	COG1116	anion transmembrane transporter activity
IVB58_10700	COG0511	ligase activity, forming carbon-carbon bonds
IVB58_10715	COG2814	Major facilitator Superfamily
IVB58_10735	COG0069	glutamate synthase activity
IVB58_10755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IVB58_10765	COG1454	alcohol dehydrogenase
IVB58_10770	COG0824	Thioesterase
IVB58_10785	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IVB58_10815	COG2030	dehydratase
IVB58_10825	COG0183	Belongs to the thiolase family
IVB58_10835	COG0583	DNA-binding transcription factor activity
IVB58_10840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IVB58_10850	COG1522	sequence-specific DNA binding
IVB58_10855	COG3135	benzoate transporter
IVB58_10865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IVB58_10890	COG0589	response to stress
IVB58_10895	COG0488	(ABC) transporter
IVB58_10915	COG4773	Receptor
IVB58_10945	COG0668	transmembrane transport
IVB58_10955	COG1309	transcriptional regulator
IVB58_10980	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IVB58_10995	COG1605	Chorismate mutase
IVB58_11035	COG0308	aminopeptidase N
IVB58_11055	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IVB58_11065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IVB58_11070	COG1454	alcohol dehydrogenase
IVB58_11090	COG0531	amino acid
IVB58_11095	COG4303	Ethanolamine ammonia lyase large subunit
IVB58_11100	COG4302	ethanolamine ammonia-lyase activity
IVB58_11105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IVB58_11105	COG0519	Catalyzes the synthesis of GMP from XMP
IVB58_11110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IVB58_11120	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IVB58_11135	COG0697	spore germination
IVB58_11140	COG1923	regulation of RNA biosynthetic process
IVB58_11150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IVB58_11155	COG0802	atpase or kinase
IVB58_11175	COG1187	pseudouridine synthase activity
IVB58_11190	COG0583	DNA-binding transcription factor activity
IVB58_11205	COG2814	Major facilitator Superfamily
IVB58_11210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IVB58_11235	COG0729	surface antigen
IVB58_11255	COG0174	glutamine synthetase
IVB58_11260	COG0745	RESPONSE REGULATOR receiver
IVB58_11265	COG2205	protein histidine kinase activity
IVB58_11275	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IVB58_11280	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IVB58_11305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IVB58_11310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IVB58_11315	COG1960	acyl-CoA dehydrogenase activity
IVB58_11330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IVB58_11335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IVB58_11355	COG0583	DNA-binding transcription factor activity
IVB58_11370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IVB58_11380	COG3658	cytochrome
IVB58_11385	COG1215	transferase activity, transferring glycosyl groups
IVB58_11390	COG1649	PFAM Uncharacterised BCR, COG1649
IVB58_11390	COG0726	polysaccharide deacetylase
IVB58_11415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IVB58_11420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IVB58_11430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IVB58_11455	COG0305	Participates in initiation and elongation during chromosome replication
IVB58_11460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IVB58_11470	COG1305	Transglutaminase-like
IVB58_11480	COG2308	Evidence 4 Homologs of previously reported genes of
IVB58_11510	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IVB58_11515	COG0138	bifunctional purine biosynthesis protein purh
IVB58_11520	COG0151	Belongs to the GarS family
IVB58_11525	COG1464	Belongs to the NlpA lipoprotein family
IVB58_11530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IVB58_11535	COG2011	ABC-type metal ion transport system permease component
IVB58_11540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IVB58_11550	COG1301	dicarboxylic acid transport
IVB58_11580	COG1794	racemase activity, acting on amino acids and derivatives
IVB58_11600	COG0745	RESPONSE REGULATOR receiver
IVB58_11605	COG0642	Histidine kinase
IVB58_11610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IVB58_11620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IVB58_11660	COG2351	hydroxyisourate hydrolase activity
IVB58_11670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IVB58_11670	COG3008	intermembrane lipid transfer
IVB58_11675	COG2995	paraquat-inducible protein a
IVB58_11705	COG0477	Major facilitator Superfamily
IVB58_11755	COG2186	Transcriptional regulator
IVB58_11765	COG0786	glutamate:sodium symporter activity
IVB58_11770	COG3243	poly(R)-hydroxyalkanoic acid synthase
IVB58_11795	COG3111	PFAM Bacterial OB fold (BOF) protein
IVB58_11865	COG2831	hemolysin activation secretion protein
IVB58_11920	COG1610	YqeY-like protein
IVB58_11925	COG4783	chaperone-mediated protein folding
IVB58_11950	COG1286	toxin biosynthetic process
IVB58_11980	COG0778	Nitroreductase
IVB58_11990	COG0513	Belongs to the DEAD box helicase family
IVB58_12010	COG2363	Small membrane protein
IVB58_12040	COG1234	tRNA 3'-trailer cleavage
IVB58_12045	COG2195	Cleaves the N-terminal amino acid of tripeptides
IVB58_12055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IVB58_12065	COG2819	hydrolase of the alpha beta superfamily
IVB58_12070	COG1960	acyl-CoA dehydrogenase activity
IVB58_12075	COG1301	dicarboxylic acid transport
IVB58_12085	COG3139	Protein of unknown function (DUF1315)
IVB58_12090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IVB58_12095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IVB58_12105	COG0494	nUDIX hydrolase
IVB58_12115	COG0642	Histidine kinase
IVB58_12130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IVB58_12140	COG1720	tRNA m6t6A37 methyltransferase activity
IVB58_12155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IVB58_12160	COG0826	peptidase U32
IVB58_12165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IVB58_12175	COG4598	ABC transporter
IVB58_12180	COG4160	amino acid transport
IVB58_12185	COG4215	(ABC) transporter
IVB58_12200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IVB58_12245	COG1131	(ABC) transporter
IVB58_12250	COG0842	Transport permease protein
IVB58_12265	COG0772	Belongs to the SEDS family
IVB58_12270	COG2951	lytic endotransglycosylase activity
IVB58_12295	COG2207	Transcriptional regulator
IVB58_12310	COG0052	Belongs to the universal ribosomal protein uS2 family
IVB58_12315	COG0024	Methionine aminopeptidase
IVB58_12325	COG2223	nitrite transmembrane transporter activity
IVB58_12335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IVB58_12340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IVB58_12345	COG1960	acyl-CoA dehydrogenase activity
IVB58_12360	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IVB58_12365	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IVB58_12370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IVB58_12390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IVB58_12395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IVB58_12400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IVB58_12435	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IVB58_12445	COG0174	glutamine synthetase
IVB58_12460	COG0512	Glutamine amidotransferase of anthranilate synthase
IVB58_12465	COG0308	aminopeptidase N
IVB58_12495	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IVB58_12505	COG0302	gtp cyclohydrolase
IVB58_12525	COG3739	integral membrane protein
IVB58_12540	COG1169	isochorismate synthase
IVB58_12545	COG2977	Belongs to the P-Pant transferase superfamily
IVB58_12550	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IVB58_12555	COG1132	(ABC) transporter
IVB58_12560	COG1132	(ABC) transporter
IVB58_12570	COG3433	isochorismatase activity
IVB58_12570	COG1535	isochorismatase
IVB58_12575	COG1021	2,3-dihydroxybenzoate-AMP ligase
IVB58_12580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IVB58_12590	COG4774	siderophore transport
IVB58_12595	COG4607	ABC-type enterochelin transport system periplasmic component
IVB58_12600	COG4604	ABC transporter, ATP-binding protein
IVB58_12605	COG4605	iron ion homeostasis
IVB58_12610	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IVB58_12615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IVB58_12630	COG2964	Protein conserved in bacteria
IVB58_12640	COG1741	Belongs to the pirin family
IVB58_12670	COG2879	small protein
IVB58_12675	COG1966	Carbon starvation protein
IVB58_12695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IVB58_12720	COG1067	ATP-dependent peptidase activity
IVB58_12725	COG0583	DNA-binding transcription factor activity
IVB58_12750	COG1686	Belongs to the peptidase S11 family
IVB58_12755	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IVB58_12790	COG0616	signal peptide processing
IVB58_12795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IVB58_12805	COG0573	inorganic phosphate transmembrane transporter activity
IVB58_12810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IVB58_12815	COG1113	amino acid transport
IVB58_12820	COG3961	Belongs to the TPP enzyme family
IVB58_12825	COG1522	sequence-specific DNA binding
IVB58_12835	COG0076	glutamate decarboxylase activity
IVB58_12840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IVB58_12865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IVB58_12900	COG0352	thiamine-phosphate diphosphorylase activity
IVB58_12925	COG0612	Peptidase, M16
IVB58_12935	COG1823	symporter activity
IVB58_12940	COG0583	DNA-binding transcription factor activity
IVB58_12945	COG0477	Major facilitator Superfamily
IVB58_12970	COG1187	pseudouridine synthase activity
IVB58_12985	COG1686	Belongs to the peptidase S11 family
IVB58_12990	COG1252	NADH dehydrogenase
IVB58_13000	COG0415	Belongs to the DNA photolyase family
IVB58_13015	COG1215	transferase activity, transferring glycosyl groups
IVB58_13045	COG2070	2-Nitropropane dioxygenase
IVB58_13100	COG0556	nucleotide-excision repair
IVB58_13120	COG0436	Aminotransferase
IVB58_13150	COG4221	oxidoreductase activity
IVB58_13160	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IVB58_13165	COG1381	Involved in DNA repair and RecF pathway recombination
IVB58_13175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IVB58_13190	COG0681	Belongs to the peptidase S26 family
IVB58_13200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IVB58_13210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IVB58_13230	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IVB58_13235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IVB58_13240	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IVB58_13250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IVB58_13255	COG4208	sulfate ABC transporter
IVB58_13260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IVB58_13265	COG0583	DNA-binding transcription factor activity
IVB58_13270	COG4625	pathogenesis
IVB58_13285	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IVB58_13300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IVB58_13310	COG1051	belongs to the nudix hydrolase family
IVB58_13310	COG1056	cytidyltransferase-related domain
IVB58_13315	COG1024	Enoyl-CoA hydratase
IVB58_13325	COG2814	Major facilitator Superfamily
IVB58_13330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IVB58_13330	COG0047	phosphoribosylformylglycinamidine synthase activity
IVB58_13350	COG1473	amidohydrolase
IVB58_13355	COG0824	Thioesterase
IVB58_13375	COG0823	Involved in the tonB-independent uptake of proteins
IVB58_13395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IVB58_13430	COG0628	permease
IVB58_13440	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IVB58_13445	COG0596	Alpha beta hydrolase
IVB58_13450	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IVB58_13450	COG0616	signal peptide processing
IVB58_13460	COG2333	competence protein COMEC
IVB58_13460	COG0658	competence protein
IVB58_13465	COG1136	(ABC) transporter
IVB58_13470	COG4591	ABC-type transport system involved in lipoprotein release permease component
IVB58_13505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IVB58_13525	COG0463	Glycosyl transferase, family 2
IVB58_13555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IVB58_13560	COG1280	lysine exporter protein (LysE YggA)
IVB58_13565	COG2267	carboxylic ester hydrolase activity
IVB58_13575	COG0019	diaminopimelate decarboxylase activity
IVB58_13585	COG1113	amino acid transport
IVB58_13600	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IVB58_13610	COG3339	Conserved Protein
IVB58_13615	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IVB58_13620	COG0243	molybdopterin cofactor binding
IVB58_13625	COG1929	Belongs to the glycerate kinase type-1 family
IVB58_13640	COG0778	Nitroreductase
IVB58_13685	COG3811	Belongs to the UPF0386 family
IVB58_13695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IVB58_13710	COG1196	nuclear chromosome segregation
IVB58_13735	COG1309	transcriptional regulator
IVB58_13760	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IVB58_13770	COG2184	nucleotidyltransferase activity
IVB58_13795	COG3152	Membrane
IVB58_13860	COG0582	viral genome integration into host DNA
IVB58_13870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IVB58_13890	COG0741	lytic transglycosylase activity
IVB58_13910	COG0584	glycerophosphoryl diester phosphodiesterase
IVB58_13915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IVB58_13980	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IVB58_13985	COG1597	lipid kinase activity
IVB58_14000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IVB58_14005	COG0477	Major facilitator Superfamily
IVB58_14055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IVB58_14060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IVB58_14085	COG0505	Belongs to the CarA family
IVB58_14105	COG0589	response to stress
IVB58_14120	COG2843	Capsule synthesis protein
IVB58_14145	COG2321	neutral zinc metallopeptidase
IVB58_14150	COG2354	Protein conserved in bacteria
IVB58_14170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IVB58_14195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IVB58_14200	COG1053	succinate dehydrogenase
IVB58_14205	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IVB58_14210	COG2009	succinate dehydrogenase
IVB58_14245	COG2921	Belongs to the UPF0250 family
IVB58_14250	COG0321	lipoyl(octanoyl) transferase activity
IVB58_14265	COG0531	amino acid
IVB58_14275	COG1733	regulation of RNA biosynthetic process
IVB58_14280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IVB58_14285	COG1648	precorrin-2 dehydrogenase activity
IVB58_14285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IVB58_14300	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IVB58_14330	COG0671	phosphoesterase, PA-phosphatase related
IVB58_14335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IVB58_14345	COG1538	Outer membrane efflux protein
IVB58_14350	COG0393	Putative heavy-metal-binding
IVB58_14355	COG0393	Putative heavy-metal-binding
IVB58_14365	COG1028	Short-chain dehydrogenase reductase Sdr
IVB58_14375	COG0525	valine-tRNA ligase activity
IVB58_14395	COG0583	DNA-binding transcription factor activity
IVB58_14400	COG0004	ammonium transporteR
IVB58_14410	COG0642	Histidine kinase
IVB58_14415	COG0745	RESPONSE REGULATOR receiver
IVB58_14420	COG2194	sulfuric ester hydrolase activity
IVB58_14440	COG1752	Esterase of the alpha-beta hydrolase superfamily
IVB58_14455	COG2315	Protein conserved in bacteria
IVB58_14460	COG0142	geranyltranstransferase activity
IVB58_14465	COG2828	Protein conserved in bacteria
IVB58_14470	COG1113	amino acid transport
IVB58_14490	COG2207	Transcriptional regulator
IVB58_14515	COG2249	NAD(P)H dehydrogenase (quinone) activity
IVB58_14525	COG0560	Phosphoserine phosphatase
IVB58_14535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IVB58_14545	COG1530	ribonuclease E activity
IVB58_14550	COG0424	maF-like protein
IVB58_14555	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IVB58_14560	COG1792	Involved in formation and maintenance of cell shape
IVB58_14565	COG1077	Cell shape determining protein MreB Mrl
IVB58_14570	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IVB58_14580	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IVB58_14610	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IVB58_14615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IVB58_14620	COG1752	Esterase of the alpha-beta hydrolase superfamily
IVB58_14625	COG1115	amino acid carrier protein
IVB58_14645	COG2814	Major facilitator Superfamily
IVB58_14650	COG1289	transmembrane transporter activity
IVB58_14660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IVB58_14700	COG1376	ErfK ybiS ycfS ynhG family protein
IVB58_14705	COG2832	Protein of unknown function (DUF454)
IVB58_14715	COG5510	response to toxic substance
IVB58_14735	COG0840	transmembrane signaling receptor activity
IVB58_14775	COG3422	double-strand break repair
IVB58_14780	COG2824	Alkylphosphonate utilization operon protein PhnA
IVB58_14785	COG3189	MarR family transcriptional regulator
IVB58_14795	COG0354	folic acid binding
IVB58_14800	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IVB58_14810	COG0679	Auxin Efflux Carrier
IVB58_14815	COG1902	pentaerythritol trinitrate reductase activity
IVB58_14820	COG4772	TonB-dependent receptor
IVB58_14825	COG2094	Belongs to the DNA glycosylase MPG family
IVB58_14850	COG1217	gtp-binding protein TYPA
IVB58_14855	COG2233	PERMEase
IVB58_14865	COG0833	amino acid
IVB58_14870	COG1690	Belongs to the RtcB family
IVB58_14880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IVB58_14880	COG2885	chlorophyll binding
IVB58_14890	COG0183	Belongs to the thiolase family
IVB58_14910	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IVB58_14930	COG2207	Transcriptional regulator
IVB58_14935	COG0183	Belongs to the thiolase family
IVB58_14965	COG1272	protein, Hemolysin III
IVB58_14970	COG0477	Major facilitator Superfamily
IVB58_14985	COG0450	alkyl hydroperoxide reductase
IVB58_15005	COG0285	dihydrofolate synthase activity
IVB58_15055	COG2096	Adenosyltransferase
IVB58_15075	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IVB58_15080	COG0745	RESPONSE REGULATOR receiver
IVB58_15085	COG2205	protein histidine kinase activity
IVB58_15095	COG1960	acyl-CoA dehydrogenase activity
IVB58_15100	COG1960	acyl-CoA dehydrogenase activity
IVB58_15150	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IVB58_15165	COG0438	transferase activity, transferring glycosyl groups
IVB58_15170	COG0463	Glycosyl transferase, family 2
IVB58_15175	COG0726	polysaccharide deacetylase
IVB58_15195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IVB58_15235	COG1862	Preprotein translocase
IVB58_15245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IVB58_15250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IVB58_15260	COG3781	membrane
IVB58_15265	COG0613	PHP domain protein
IVB58_15275	COG2350	Protein conserved in bacteria
IVB58_15300	COG0582	viral genome integration into host DNA
IVB58_15350	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IVB58_15375	COG2132	Multicopper oxidase
IVB58_15390	COG2205	protein histidine kinase activity
IVB58_15470	COG3013	Belongs to the UPF0304 family
IVB58_15500	COG1607	acyl-coa hydrolase
IVB58_15560	COG2199	diguanylate cyclase activity
IVB58_15570	COG1408	metallophosphoesterase
IVB58_15575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IVB58_15585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IVB58_15605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IVB58_15610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IVB58_15615	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IVB58_15625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IVB58_15635	COG2969	positive regulation of protein catabolic process
IVB58_15655	COG1960	acyl-CoA dehydrogenase activity
IVB58_15660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IVB58_15675	COG1309	transcriptional regulator
IVB58_15680	COG1960	acyl-CoA dehydrogenase activity
IVB58_15725	COG1183	phosphatidylcholine synthase activity
IVB58_15730	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IVB58_15760	COG1196	nuclear chromosome segregation
IVB58_15760	COG0739	heme binding
IVB58_15760	COG0741	lytic transglycosylase activity
IVB58_15770	COG1702	phosphate starvation-inducible protein PhoH
IVB58_15805	COG1295	ribonuclease BN
IVB58_15810	COG0697	spore germination
IVB58_15815	COG2169	Transcriptional regulator
IVB58_15820	COG0179	Fumarylacetoacetate (FAA) hydrolase
IVB58_15860	COG0557	exoribonuclease II activity
IVB58_15865	COG0339	signal peptide processing
IVB58_15870	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IVB58_15900	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IVB58_15905	COG1960	acyl-CoA dehydrogenase activity
IVB58_16060	COG0626	cystathionine gamma-synthase activity
IVB58_16065	COG0433	COG0433 Predicted ATPase
IVB58_16075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IVB58_16075	COG1017	nitric oxide dioxygenase activity
IVB58_16080	COG1959	2 iron, 2 sulfur cluster binding
IVB58_16095	COG1301	dicarboxylic acid transport
IVB58_16100	COG1946	Acyl-CoA thioesterase
IVB58_16120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IVB58_16125	COG1040	competence protein
IVB58_16130	COG0494	nUDIX hydrolase
IVB58_16140	COG0598	Magnesium transport protein CorA
IVB58_16150	COG2854	intermembrane phospholipid transfer
IVB58_16160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IVB58_16165	COG1127	ABC transporter
IVB58_16175	COG0513	Belongs to the DEAD box helicase family
IVB58_16195	COG0408	coproporphyrinogen oxidase activity
IVB58_16210	COG1960	acyl-CoA dehydrogenase activity
IVB58_16220	COG1983	PspC domain protein
IVB58_16225	COG0517	IMP dehydrogenase activity
IVB58_16250	COG0752	glycyl-tRNA synthetase alpha subunit
IVB58_16270	COG0583	DNA-binding transcription factor activity
IVB58_16310	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_16320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IVB58_16325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IVB58_16330	COG0833	amino acid
IVB58_16360	COG1192	Involved in chromosome partitioning
IVB58_16365	COG0628	permease
IVB58_16375	COG1289	transmembrane transporter activity
IVB58_16390	COG2249	NAD(P)H dehydrogenase (quinone) activity
IVB58_16395	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IVB58_16405	COG0277	FAD linked oxidase domain protein
IVB58_16410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IVB58_16435	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IVB58_16440	COG5380	lipid catabolic process
IVB58_16460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IVB58_16510	COG0194	GDP metabolic process
IVB58_16525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IVB58_16545	COG3307	-O-antigen
IVB58_16550	COG4969	Belongs to the N-Me-Phe pilin family
IVB58_16560	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IVB58_16565	COG1704	LemA family
IVB58_16575	COG0493	'glutamate synthase
IVB58_16580	COG0070	glutamate synthase
IVB58_16580	COG0067	glutamate synthase
IVB58_16580	COG0069	glutamate synthase activity
IVB58_16630	COG2226	methyltransferase
IVB58_16645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IVB58_16650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IVB58_16695	COG0833	amino acid
IVB58_16760	COG0488	(ABC) transporter
IVB58_16765	COG2873	o-acetylhomoserine
IVB58_16770	COG4221	oxidoreductase activity
IVB58_16775	COG0659	secondary active sulfate transmembrane transporter activity
IVB58_16800	COG0427	acetyl-CoA hydrolase
IVB58_16830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IVB58_16870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IVB58_16925	COG0582	viral genome integration into host DNA
IVB58_16960	COG0305	Participates in initiation and elongation during chromosome replication
IVB58_17015	COG0629	single-stranded DNA binding
IVB58_17040	COG2249	NAD(P)H dehydrogenase (quinone) activity
IVB58_17045	COG1733	regulation of RNA biosynthetic process
IVB58_17090	COG0667	Aldo Keto reductase
IVB58_17110	COG0583	DNA-binding transcription factor activity
IVB58_17115	COG2814	Major facilitator Superfamily
IVB58_17145	COG1335	isochorismatase
IVB58_17155	COG1012	belongs to the aldehyde dehydrogenase family
IVB58_17160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IVB58_17170	COG1113	amino acid transport
IVB58_17180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IVB58_17190	COG1196	nuclear chromosome segregation
IVB58_17220	COG2814	Major facilitator Superfamily
IVB58_17230	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IVB58_17230	COG0352	thiamine-phosphate diphosphorylase activity
IVB58_17230	COG0351	phosphomethylpyrimidine kinase
IVB58_17250	COG1309	transcriptional regulator
IVB58_17255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IVB58_17270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IVB58_17280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IVB58_17285	COG3162	membrane
IVB58_17290	COG2198	Histidine kinase
IVB58_17290	COG0784	Response regulator, receiver
IVB58_17290	COG2205	protein histidine kinase activity
IVB58_17315	COG1522	sequence-specific DNA binding
IVB58_17320	COG1335	isochorismatase
IVB58_17325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IVB58_17335	COG0668	transmembrane transport
IVB58_17340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IVB58_17345	COG1519	Transferase
IVB58_17350	COG1902	pentaerythritol trinitrate reductase activity
IVB58_17370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IVB58_17395	COG0426	domain, Protein
IVB58_17395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IVB58_17400	COG4774	siderophore transport
IVB58_17405	COG2119	membrane
IVB58_17415	COG0508	dehydrogenase complex catalyzes the overall conversion of
IVB58_17425	COG4942	peptidase
IVB58_17440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IVB58_17450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IVB58_17470	COG0189	ligase activity
IVB58_17500	COG0708	Exodeoxyribonuclease III
IVB58_17505	COG1393	Belongs to the ArsC family
IVB58_17520	COG3706	GGDEF domain
IVB58_17555	COG2351	hydroxyisourate hydrolase activity
IVB58_17560	COG2233	PERMEase
IVB58_17570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IVB58_17580	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IVB58_17590	COG3150	esterase
IVB58_17630	COG1705	Flagellar rod assembly protein muramidase FlgJ
IVB58_17630	COG3951	Flagellar rod assembly protein muramidase FlgJ
IVB58_17650	COG2918	glutathione biosynthetic process
IVB58_17665	COG2733	membrane
IVB58_17670	COG0436	Aminotransferase
IVB58_17675	COG0534	Mate efflux family protein
IVB58_17760	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IVB58_17765	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IVB58_17775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IVB58_17780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IVB58_17795	COG0010	Belongs to the arginase family
IVB58_17825	COG2188	Transcriptional regulator
IVB58_17835	COG0523	cobalamin synthesis protein
IVB58_17845	COG1113	amino acid transport
IVB58_17855	COG0625	glutathione transferase activity
IVB58_17875	COG1683	Conserved Protein
IVB58_17880	COG0534	Mate efflux family protein
IVB58_17885	COG0385	Bile acid
IVB58_17890	COG1335	isochorismatase
IVB58_17895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IVB58_17915	COG2116	formate transmembrane transporter activity
IVB58_17920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IVB58_17925	COG2133	pyrroloquinoline quinone binding
IVB58_17930	COG2983	Belongs to the UPF0260 family
IVB58_17950	COG1194	a g-specific adenine glycosylase
IVB58_17965	COG2818	Glycosylase
IVB58_17970	COG1064	alcohol dehydrogenase
IVB58_17975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IVB58_17990	COG0583	DNA-binding transcription factor activity
IVB58_17995	COG0656	L-ascorbic acid biosynthetic process
IVB58_18000	COG2814	Major facilitator Superfamily
IVB58_18035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IVB58_18050	COG2233	PERMEase
IVB58_18055	COG0583	DNA-binding transcription factor activity
IVB58_18090	COG0733	neurotransmitter:sodium symporter activity
IVB58_18130	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IVB58_18135	COG0657	acetylesterase activity
IVB58_18185	COG2951	lytic endotransglycosylase activity
IVB58_18190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IVB58_18205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IVB58_18215	COG0671	phosphoesterase, PA-phosphatase related
IVB58_18220	COG0861	Integral membrane protein TerC family
IVB58_18230	COG0754	glutathionylspermidine amidase activity
IVB58_18240	COG0402	S-adenosylhomocysteine deaminase activity
IVB58_18255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IVB58_18260	COG1230	cation diffusion facilitator family transporter
IVB58_18275	COG0706	membrane insertase activity
IVB58_18295	COG1192	Involved in chromosome partitioning
IVB58_18300	COG1475	DNA binding
IVB58_18355	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IVB58_18435	COG3173	Aminoglycoside phosphotransferase
IVB58_18440	COG0488	(ABC) transporter
IVB58_18555	COG0582	viral genome integration into host DNA
IVB58_18640	COG3328	transposase activity
IVB58_18685	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity