locus-tag	class	description
H1I71_00010	COG0592	DNA-directed DNA polymerase activity
H1I71_00020	COG0187	DNA topoisomerase II activity
H1I71_00030	COG0586	Pfam SNARE associated Golgi protein
H1I71_00035	COG0488	(ABC) transporter
H1I71_00060	COG0596	Alpha beta hydrolase
H1I71_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1I71_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1I71_00110	COG0733	neurotransmitter:sodium symporter activity
H1I71_00150	COG2233	PERMEase
H1I71_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_00200	COG2814	Major facilitator Superfamily
H1I71_00205	COG0656	L-ascorbic acid biosynthetic process
H1I71_00210	COG0583	DNA-binding transcription factor activity
H1I71_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I71_00230	COG1064	alcohol dehydrogenase
H1I71_00235	COG2818	Glycosylase
H1I71_00250	COG1194	a g-specific adenine glycosylase
H1I71_00270	COG2983	Belongs to the UPF0260 family
H1I71_00275	COG2133	pyrroloquinoline quinone binding
H1I71_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1I71_00285	COG2116	formate transmembrane transporter activity
H1I71_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I71_00310	COG1335	isochorismatase
H1I71_00315	COG0385	Bile acid
H1I71_00320	COG0534	Mate efflux family protein
H1I71_00325	COG1683	Conserved Protein
H1I71_00345	COG0625	glutathione transferase activity
H1I71_00355	COG1113	amino acid transport
H1I71_00365	COG0523	cobalamin synthesis protein
H1I71_00375	COG2188	Transcriptional regulator
H1I71_00405	COG0010	Belongs to the arginase family
H1I71_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I71_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1I71_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1I71_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1I71_00540	COG0534	Mate efflux family protein
H1I71_00545	COG0436	Aminotransferase
H1I71_00550	COG2733	membrane
H1I71_00565	COG2918	glutathione biosynthetic process
H1I71_00580	COG1388	LysM domain
H1I71_00580	COG0791	NLP P60 protein
H1I71_00595	COG3150	esterase
H1I71_00605	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H1I71_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I71_00630	COG2233	PERMEase
H1I71_00635	COG2351	hydroxyisourate hydrolase activity
H1I71_00670	COG3706	GGDEF domain
H1I71_00685	COG1393	Belongs to the ArsC family
H1I71_00690	COG0708	Exodeoxyribonuclease III
H1I71_00710	COG0189	ligase activity
H1I71_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1I71_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1I71_00755	COG4942	peptidase
H1I71_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I71_00775	COG2119	membrane
H1I71_00780	COG4774	siderophore transport
H1I71_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I71_00785	COG0426	domain, Protein
H1I71_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1I71_00830	COG1902	pentaerythritol trinitrate reductase activity
H1I71_00835	COG1519	Transferase
H1I71_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I71_00845	COG0668	transmembrane transport
H1I71_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I71_00860	COG1335	isochorismatase
H1I71_00865	COG1522	sequence-specific DNA binding
H1I71_00870	COG3328	transposase activity
H1I71_00900	COG2205	protein histidine kinase activity
H1I71_00900	COG2198	Histidine kinase
H1I71_00900	COG0784	Response regulator, receiver
H1I71_00905	COG3162	membrane
H1I71_00910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I71_00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I71_00940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1I71_00945	COG1309	transcriptional regulator
H1I71_00965	COG0351	phosphomethylpyrimidine kinase
H1I71_00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I71_00965	COG0352	thiamine-phosphate diphosphorylase activity
H1I71_00975	COG2814	Major facilitator Superfamily
H1I71_00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I71_01000	COG1113	amino acid transport
H1I71_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I71_01015	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_01025	COG1335	isochorismatase
H1I71_01055	COG2814	Major facilitator Superfamily
H1I71_01060	COG0583	DNA-binding transcription factor activity
H1I71_01080	COG0667	Aldo Keto reductase
H1I71_01110	COG1733	regulation of RNA biosynthetic process
H1I71_01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I71_01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1I71_01195	COG2329	Antibiotic biosynthesis monooxygenase
H1I71_01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1I71_01255	COG0427	acetyl-CoA hydrolase
H1I71_01280	COG0659	secondary active sulfate transmembrane transporter activity
H1I71_01285	COG4221	oxidoreductase activity
H1I71_01290	COG2873	o-acetylhomoserine
H1I71_01295	COG0488	(ABC) transporter
H1I71_01380	COG0833	amino acid
H1I71_01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1I71_01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1I71_01445	COG2226	methyltransferase
H1I71_01495	COG0067	glutamate synthase
H1I71_01495	COG0069	glutamate synthase activity
H1I71_01495	COG0070	glutamate synthase
H1I71_01500	COG0493	'glutamate synthase
H1I71_01510	COG1704	LemA family
H1I71_01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1I71_01535	COG3307	-O-antigen
H1I71_01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I71_01575	COG0194	GDP metabolic process
H1I71_01625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1I71_01645	COG5380	lipid catabolic process
H1I71_01650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1I71_01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1I71_01680	COG0277	FAD linked oxidase domain protein
H1I71_01690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1I71_01695	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I71_01710	COG1289	transmembrane transporter activity
H1I71_01720	COG0628	permease
H1I71_01725	COG1192	Involved in chromosome partitioning
H1I71_01755	COG0833	amino acid
H1I71_01760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I71_01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I71_01775	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_01815	COG0583	DNA-binding transcription factor activity
H1I71_01860	COG0517	IMP dehydrogenase activity
H1I71_01865	COG1983	PspC domain protein
H1I71_01875	COG1960	acyl-CoA dehydrogenase activity
H1I71_01890	COG0408	coproporphyrinogen oxidase activity
H1I71_01910	COG0513	Belongs to the DEAD box helicase family
H1I71_01920	COG1127	ABC transporter
H1I71_01925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1I71_01935	COG2854	intermembrane phospholipid transfer
H1I71_01945	COG0598	Magnesium transport protein CorA
H1I71_01955	COG0494	nUDIX hydrolase
H1I71_01960	COG1040	competence protein
H1I71_01965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1I71_01985	COG1946	Acyl-CoA thioesterase
H1I71_01990	COG1301	dicarboxylic acid transport
H1I71_02005	COG1959	2 iron, 2 sulfur cluster binding
H1I71_02010	COG1017	nitric oxide dioxygenase activity
H1I71_02010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I71_02015	COG0433	COG0433 Predicted ATPase
H1I71_02020	COG0626	cystathionine gamma-synthase activity
H1I71_02175	COG1960	acyl-CoA dehydrogenase activity
H1I71_02180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1I71_02210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1I71_02215	COG0339	signal peptide processing
H1I71_02220	COG0557	exoribonuclease II activity
H1I71_02260	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1I71_02265	COG2169	Transcriptional regulator
H1I71_02270	COG0697	spore germination
H1I71_02275	COG1295	ribonuclease BN
H1I71_02310	COG1702	phosphate starvation-inducible protein PhoH
H1I71_02320	COG0741	lytic transglycosylase activity
H1I71_02320	COG1196	nuclear chromosome segregation
H1I71_02320	COG0739	heme binding
H1I71_02350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1I71_02355	COG1183	phosphatidylcholine synthase activity
H1I71_02400	COG1960	acyl-CoA dehydrogenase activity
H1I71_02405	COG1309	transcriptional regulator
H1I71_02420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I71_02425	COG1960	acyl-CoA dehydrogenase activity
H1I71_02445	COG2969	positive regulation of protein catabolic process
H1I71_02455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1I71_02470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1I71_02475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1I71_02495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1I71_02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I71_02510	COG1408	metallophosphoesterase
H1I71_02520	COG2199	diguanylate cyclase activity
H1I71_02580	COG1607	acyl-coa hydrolase
H1I71_02610	COG2350	Protein conserved in bacteria
H1I71_02620	COG0613	PHP domain protein
H1I71_02625	COG3781	membrane
H1I71_02635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1I71_02640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1I71_02650	COG1862	Preprotein translocase
H1I71_02680	COG2205	protein histidine kinase activity
H1I71_02685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H1I71_02705	COG0726	polysaccharide deacetylase
H1I71_02710	COG0463	Glycosyl transferase, family 2
H1I71_02715	COG0438	transferase activity, transferring glycosyl groups
H1I71_02780	COG0625	glutathione transferase activity
H1I71_02785	COG0583	DNA-binding transcription factor activity
H1I71_02790	COG1960	acyl-CoA dehydrogenase activity
H1I71_02795	COG1960	acyl-CoA dehydrogenase activity
H1I71_02805	COG2205	protein histidine kinase activity
H1I71_02810	COG0745	RESPONSE REGULATOR receiver
H1I71_02815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H1I71_02835	COG2096	Adenosyltransferase
H1I71_02885	COG0285	dihydrofolate synthase activity
H1I71_02905	COG0450	alkyl hydroperoxide reductase
H1I71_02920	COG0477	Major facilitator Superfamily
H1I71_02925	COG1272	protein, Hemolysin III
H1I71_02955	COG0183	Belongs to the thiolase family
H1I71_02960	COG2207	Transcriptional regulator
H1I71_02980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I71_03000	COG0183	Belongs to the thiolase family
H1I71_03010	COG2885	chlorophyll binding
H1I71_03010	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1I71_03020	COG1690	Belongs to the RtcB family
H1I71_03025	COG0833	amino acid
H1I71_03035	COG2233	PERMEase
H1I71_03040	COG1217	gtp-binding protein TYPA
H1I71_03065	COG2094	Belongs to the DNA glycosylase MPG family
H1I71_03070	COG4772	TonB-dependent receptor
H1I71_03085	COG1902	pentaerythritol trinitrate reductase activity
H1I71_03090	COG0679	Auxin Efflux Carrier
H1I71_03100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I71_03105	COG0354	folic acid binding
H1I71_03115	COG3189	MarR family transcriptional regulator
H1I71_03120	COG2824	Alkylphosphonate utilization operon protein PhnA
H1I71_03125	COG3422	double-strand break repair
H1I71_03165	COG0840	transmembrane signaling receptor activity
H1I71_03185	COG5510	response to toxic substance
H1I71_03195	COG2832	Protein of unknown function (DUF454)
H1I71_03200	COG1376	ErfK ybiS ycfS ynhG family protein
H1I71_03240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1I71_03250	COG1289	transmembrane transporter activity
H1I71_03255	COG2814	Major facilitator Superfamily
H1I71_03275	COG1115	amino acid carrier protein
H1I71_03280	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I71_03285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I71_03290	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1I71_03320	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I71_03330	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I71_03335	COG1077	Cell shape determining protein MreB Mrl
H1I71_03340	COG1792	Involved in formation and maintenance of cell shape
H1I71_03345	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1I71_03350	COG0424	maF-like protein
H1I71_03355	COG1530	ribonuclease E activity
H1I71_03365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I71_03375	COG0560	Phosphoserine phosphatase
H1I71_03385	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I71_03410	COG2207	Transcriptional regulator
H1I71_03430	COG1113	amino acid transport
H1I71_03435	COG2828	Protein conserved in bacteria
H1I71_03440	COG0142	geranyltranstransferase activity
H1I71_03445	COG2315	Protein conserved in bacteria
H1I71_03460	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I71_03480	COG2194	sulfuric ester hydrolase activity
H1I71_03485	COG0745	RESPONSE REGULATOR receiver
H1I71_03490	COG0642	Histidine kinase
H1I71_03500	COG0004	ammonium transporteR
H1I71_03505	COG0583	DNA-binding transcription factor activity
H1I71_03525	COG0525	valine-tRNA ligase activity
H1I71_03535	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_03545	COG0393	Putative heavy-metal-binding
H1I71_03550	COG0393	Putative heavy-metal-binding
H1I71_03555	COG1538	Outer membrane efflux protein
H1I71_03565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_03570	COG0671	phosphoesterase, PA-phosphatase related
H1I71_03600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1I71_03615	COG1648	precorrin-2 dehydrogenase activity
H1I71_03615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1I71_03620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1I71_03625	COG1733	regulation of RNA biosynthetic process
H1I71_03635	COG0531	amino acid
H1I71_03650	COG0321	lipoyl(octanoyl) transferase activity
H1I71_03655	COG2921	Belongs to the UPF0250 family
H1I71_03695	COG2009	succinate dehydrogenase
H1I71_03700	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1I71_03705	COG1053	succinate dehydrogenase
H1I71_03710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1I71_03735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I71_03755	COG2354	Protein conserved in bacteria
H1I71_03760	COG2321	neutral zinc metallopeptidase
H1I71_03790	COG2843	Capsule synthesis protein
H1I71_03805	COG0589	response to stress
H1I71_03825	COG0505	Belongs to the CarA family
H1I71_03850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I71_03855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1I71_03905	COG0477	Major facilitator Superfamily
H1I71_03910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1I71_03925	COG1597	lipid kinase activity
H1I71_03930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I71_03960	COG0584	glycerophosphoryl diester phosphodiesterase
H1I71_03980	COG0741	lytic transglycosylase activity
H1I71_04000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1I71_04015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I71_04040	COG0778	Nitroreductase
H1I71_04055	COG1929	Belongs to the glycerate kinase type-1 family
H1I71_04060	COG0243	molybdopterin cofactor binding
H1I71_04065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1I71_04070	COG3339	Conserved Protein
H1I71_04080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H1I71_04095	COG1113	amino acid transport
H1I71_04105	COG0019	diaminopimelate decarboxylase activity
H1I71_04115	COG1280	lysine exporter protein (LysE YggA)
H1I71_04120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I71_04150	COG0463	Glycosyl transferase, family 2
H1I71_04170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_04205	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1I71_04210	COG1136	(ABC) transporter
H1I71_04215	COG2333	competence protein COMEC
H1I71_04215	COG0658	competence protein
H1I71_04225	COG0616	signal peptide processing
H1I71_04225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1I71_04230	COG0596	Alpha beta hydrolase
H1I71_04235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1I71_04245	COG0628	permease
H1I71_04280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I71_04300	COG0823	Involved in the tonB-independent uptake of proteins
H1I71_04320	COG0824	Thioesterase
H1I71_04325	COG1473	amidohydrolase
H1I71_04345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1I71_04345	COG0047	phosphoribosylformylglycinamidine synthase activity
H1I71_04350	COG2814	Major facilitator Superfamily
H1I71_04360	COG1024	Enoyl-CoA hydratase
H1I71_04365	COG1051	belongs to the nudix hydrolase family
H1I71_04365	COG1056	cytidyltransferase-related domain
H1I71_04375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1I71_04390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1I71_04405	COG4625	pathogenesis
H1I71_04410	COG0583	DNA-binding transcription factor activity
H1I71_04415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1I71_04420	COG4208	sulfate ABC transporter
H1I71_04425	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1I71_04435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1I71_04440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1I71_04445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1I71_04465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I71_04480	COG0681	Belongs to the peptidase S26 family
H1I71_04495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1I71_04505	COG1381	Involved in DNA repair and RecF pathway recombination
H1I71_04510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1I71_04520	COG4221	oxidoreductase activity
H1I71_04550	COG0436	Aminotransferase
H1I71_04570	COG0556	nucleotide-excision repair
H1I71_04625	COG2070	2-Nitropropane dioxygenase
H1I71_04655	COG1215	transferase activity, transferring glycosyl groups
H1I71_04670	COG0415	Belongs to the DNA photolyase family
H1I71_04680	COG1252	NADH dehydrogenase
H1I71_04685	COG1686	Belongs to the peptidase S11 family
H1I71_04700	COG1187	pseudouridine synthase activity
H1I71_04725	COG0477	Major facilitator Superfamily
H1I71_04730	COG0583	DNA-binding transcription factor activity
H1I71_04735	COG1823	symporter activity
H1I71_04745	COG0612	Peptidase, M16
H1I71_04770	COG0352	thiamine-phosphate diphosphorylase activity
H1I71_04805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I71_04820	COG1309	transcriptional regulator
H1I71_04830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I71_04835	COG0076	glutamate decarboxylase activity
H1I71_04845	COG1522	sequence-specific DNA binding
H1I71_04850	COG3961	Belongs to the TPP enzyme family
H1I71_04855	COG1113	amino acid transport
H1I71_04860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I71_04865	COG0573	inorganic phosphate transmembrane transporter activity
H1I71_04875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1I71_04880	COG0616	signal peptide processing
H1I71_04915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1I71_04920	COG1686	Belongs to the peptidase S11 family
H1I71_04945	COG0583	DNA-binding transcription factor activity
H1I71_04950	COG1067	ATP-dependent peptidase activity
H1I71_04995	COG1966	Carbon starvation protein
H1I71_05000	COG2879	small protein
H1I71_05030	COG2508	Transcriptional regulator
H1I71_05030	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1I71_05050	COG1113	amino acid transport
H1I71_05055	COG0583	DNA-binding transcription factor activity
H1I71_05060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I71_05065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I71_05075	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_05080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I71_05085	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H1I71_05085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I71_05120	COG2814	Major facilitator Superfamily
H1I71_05125	COG4948	Mandelate Racemase Muconate Lactonizing
H1I71_05135	COG1309	transcriptional regulator
H1I71_05155	COG1741	Belongs to the pirin family
H1I71_05165	COG2964	Protein conserved in bacteria
H1I71_05180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I71_05185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I71_05190	COG4605	iron ion homeostasis
H1I71_05195	COG4604	ABC transporter, ATP-binding protein
H1I71_05200	COG4607	ABC-type enterochelin transport system periplasmic component
H1I71_05205	COG4774	siderophore transport
H1I71_05215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I71_05220	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1I71_05225	COG3433	isochorismatase activity
H1I71_05225	COG1535	isochorismatase
H1I71_05240	COG1132	(ABC) transporter
H1I71_05245	COG1132	(ABC) transporter
H1I71_05250	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H1I71_05260	COG1169	isochorismate synthase
H1I71_05275	COG3739	integral membrane protein
H1I71_05300	COG0302	gtp cyclohydrolase
H1I71_05310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1I71_05340	COG0308	aminopeptidase N
H1I71_05345	COG0512	Glutamine amidotransferase of anthranilate synthase
H1I71_05360	COG0174	glutamine synthetase
H1I71_05370	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H1I71_05405	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1I71_05410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1I71_05415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I71_05435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I71_05440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1I71_05445	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1I71_05460	COG1960	acyl-CoA dehydrogenase activity
H1I71_05465	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I71_05470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I71_05480	COG2223	nitrite transmembrane transporter activity
H1I71_05490	COG0024	Methionine aminopeptidase
H1I71_05495	COG0052	Belongs to the universal ribosomal protein uS2 family
H1I71_05510	COG2207	Transcriptional regulator
H1I71_05535	COG2951	lytic endotransglycosylase activity
H1I71_05540	COG0772	Belongs to the SEDS family
H1I71_05555	COG0842	Transport permease protein
H1I71_05560	COG1131	(ABC) transporter
H1I71_05605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_05620	COG4215	(ABC) transporter
H1I71_05625	COG4160	amino acid transport
H1I71_05630	COG4598	ABC transporter
H1I71_05640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I71_05645	COG0826	peptidase U32
H1I71_05650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I71_05665	COG1720	tRNA m6t6A37 methyltransferase activity
H1I71_05675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1I71_05690	COG0642	Histidine kinase
H1I71_05700	COG0494	nUDIX hydrolase
H1I71_05710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1I71_05715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1I71_05720	COG3139	Protein of unknown function (DUF1315)
H1I71_05725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1I71_05730	COG1301	dicarboxylic acid transport
H1I71_05735	COG1960	acyl-CoA dehydrogenase activity
H1I71_05740	COG2819	hydrolase of the alpha beta superfamily
H1I71_05750	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1I71_05760	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1I71_05765	COG1234	tRNA 3'-trailer cleavage
H1I71_05795	COG2363	Small membrane protein
H1I71_05815	COG0513	Belongs to the DEAD box helicase family
H1I71_05825	COG0778	Nitroreductase
H1I71_06170	COG1286	toxin biosynthetic process
H1I71_06195	COG4783	chaperone-mediated protein folding
H1I71_06200	COG1610	YqeY-like protein
H1I71_06300	COG3111	PFAM Bacterial OB fold (BOF) protein
H1I71_06325	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1I71_06330	COG0786	glutamate:sodium symporter activity
H1I71_06340	COG2186	Transcriptional regulator
H1I71_06390	COG0477	Major facilitator Superfamily
H1I71_06415	COG2985	domain, Protein
H1I71_06425	COG2995	paraquat-inducible protein a
H1I71_06430	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1I71_06430	COG3008	intermembrane lipid transfer
H1I71_06440	COG1794	racemase activity, acting on amino acids and derivatives
H1I71_06525	COG0482	sulfurtransferase activity
H1I71_06540	COG0488	(ABC) transporter
H1I71_06545	COG3173	Aminoglycoside phosphotransferase
H1I71_06555	COG2433	Pfam Transposase IS66
H1I71_06575	COG1309	transcriptional regulator
H1I71_06580	COG1741	Belongs to the pirin family
H1I71_06595	COG2072	flavoprotein involved in K transport
H1I71_06605	COG2252	PERMEase
H1I71_06610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1I71_06615	COG3038	cytochrome b561
H1I71_06625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1I71_06635	COG0527	aspartate kinase activity
H1I71_06645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1I71_06655	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1I71_06670	COG0667	Aldo Keto reductase
H1I71_06685	COG1765	OsmC-like protein
H1I71_06700	COG0542	response to heat
H1I71_06735	COG2885	chlorophyll binding
H1I71_06745	COG0625	glutathione transferase activity
H1I71_06750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1I71_06770	COG3634	alkyl hydroperoxide reductase activity
H1I71_06780	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1I71_06790	COG0450	alkyl hydroperoxide reductase
H1I71_06795	COG1643	Atp-dependent helicase
H1I71_06810	COG2814	Major facilitator Superfamily
H1I71_06815	COG3135	benzoate transporter
H1I71_06820	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_06825	COG0543	2 iron, 2 sulfur cluster binding
H1I71_06825	COG0633	Ferredoxin
H1I71_06830	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I71_06835	COG4638	Rieske (2fe-2S)
H1I71_06840	COG0583	DNA-binding transcription factor activity
H1I71_06890	COG1570	exodeoxyribonuclease VII activity
H1I71_06920	COG1280	lysine exporter protein (LysE YggA)
H1I71_06925	COG1278	Cold shock
H1I71_06960	COG2814	Major facilitator Superfamily
H1I71_06995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1I71_06995	COG0517	IMP dehydrogenase activity
H1I71_07000	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1I71_07010	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1I71_07015	COG1137	ATPase activity
H1I71_07020	COG1538	Outer membrane efflux protein
H1I71_07050	COG4122	O-methyltransferase activity
H1I71_07060	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1I71_07075	COG1522	sequence-specific DNA binding
H1I71_07080	COG5006	permease, DMT superfamily
H1I71_07090	COG1560	Kdo2-lipid A biosynthetic process
H1I71_07100	COG2814	Major facilitator Superfamily
H1I71_07120	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I71_07170	COG0583	DNA-binding transcription factor activity
H1I71_07175	COG1914	H( )-stimulated, divalent metal cation uptake system
H1I71_07195	COG4770	biotin carboxylase activity
H1I71_07200	COG0038	chloride channel
H1I71_07220	COG1309	transcriptional regulator
H1I71_07230	COG1063	alcohol dehydrogenase
H1I71_07245	COG0439	Biotin carboxylase
H1I71_07250	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I71_07270	COG0864	Transcriptional regulator
H1I71_07280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I71_07285	COG1116	anion transmembrane transporter activity
H1I71_07400	COG0590	tRNA wobble adenosine to inosine editing
H1I71_07405	COG2807	transmembrane transport
H1I71_07420	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1I71_07440	COG0583	DNA-binding transcription factor activity
H1I71_07490	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_07510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I71_07530	COG0784	Response regulator, receiver
H1I71_07530	COG2205	protein histidine kinase activity
H1I71_07550	COG0765	amino acid transport
H1I71_07555	COG0765	amino acid transport
H1I71_07560	COG1126	abc transporter atp-binding protein
H1I71_07565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I71_07570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I71_07585	COG1280	lysine exporter protein (LysE YggA)
H1I71_07595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1I71_07600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I71_07605	COG1045	serine acetyltransferase
H1I71_07620	COG0583	DNA-binding transcription factor activity
H1I71_07625	COG0625	glutathione transferase activity
H1I71_07630	COG0625	glutathione transferase activity
H1I71_07635	COG0583	DNA-binding transcription factor activity
H1I71_07645	COG1346	cytolysis
H1I71_07665	COG2814	Major facilitator Superfamily
H1I71_07675	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H1I71_07680	COG3052	prosthetic group binding
H1I71_07700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1I71_07720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I71_07730	COG1294	oxidase, subunit
H1I71_07735	COG1271	oxidase subunit
H1I71_07755	COG0477	Major facilitator Superfamily
H1I71_07765	COG4521	taurine ABC transporter
H1I71_07770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1I71_07775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I71_07780	COG2175	clavaminate synthase activity
H1I71_07790	COG1953	Uracil, thiamine, allantoin
H1I71_07800	COG0583	DNA-binding transcription factor activity
H1I71_07810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1I71_07825	COG0640	Transcriptional regulator
H1I71_07830	COG0798	PFAM Bile acid sodium symporter
H1I71_07835	COG0583	DNA-binding transcription factor activity
H1I71_07850	COG3634	alkyl hydroperoxide reductase activity
H1I71_07890	COG0436	Aminotransferase
H1I71_07900	COG0386	Belongs to the glutathione peroxidase family
H1I71_07940	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I71_07965	COG0012	GTP binding
H1I71_07970	COG2011	ABC-type metal ion transport system permease component
H1I71_07975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I71_07985	COG1464	Belongs to the NlpA lipoprotein family
H1I71_08015	COG0765	amino acid transport
H1I71_08020	COG0765	amino acid transport
H1I71_08025	COG1126	abc transporter atp-binding protein
H1I71_08040	COG1522	sequence-specific DNA binding
H1I71_08055	COG1309	transcriptional regulator
H1I71_08075	COG0583	DNA-binding transcription factor activity
H1I71_08085	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I71_08095	COG0697	spore germination
H1I71_08120	COG3121	Chaperone
H1I71_08125	COG3539	Fimbrial protein
H1I71_08150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1I71_08150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1I71_08195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1I71_08205	COG2353	YceI-like domain
H1I71_08215	COG3698	Phosphodiester glycosidase
H1I71_08230	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H1I71_08235	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I71_08235	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I71_08235	COG0506	proline dehydrogenase activity
H1I71_08245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I71_08250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1I71_08270	COG1132	(ABC) transporter
H1I71_08275	COG3122	Protein conserved in bacteria
H1I71_08280	COG3619	membrane
H1I71_08290	COG0640	Transcriptional regulator
H1I71_08300	COG2850	peptidyl-arginine hydroxylation
H1I71_08305	COG0424	maF-like protein
H1I71_08325	COG0191	fructose-bisphosphate aldolase activity
H1I71_08330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I71_08345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1I71_08355	COG1192	Involved in chromosome partitioning
H1I71_08360	COG1475	DNA binding
H1I71_08365	COG0811	peptide transport
H1I71_08375	COG1132	(ABC) transporter
H1I71_08380	COG1663	tetraacyldisaccharide 4'-kinase activity
H1I71_08400	COG0084	hydrolase, TatD family'
H1I71_08465	COG0776	regulation of translation
H1I71_08495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1I71_08500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1I71_08560	COG0339	signal peptide processing
H1I71_08570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1I71_08605	COG0702	epimerase
H1I71_08610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I71_08635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1I71_08665	COG0316	Belongs to the HesB IscA family
H1I71_08670	COG0822	iron-sulfur transferase activity
H1I71_08695	COG0776	regulation of translation
H1I71_08700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I71_08705	COG2207	Transcriptional regulator
H1I71_08710	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I71_08715	COG1960	acyl-CoA dehydrogenase activity
H1I71_08720	COG1960	acyl-CoA dehydrogenase activity
H1I71_08735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1I71_08755	COG4264	IucA IucC family
H1I71_08760	COG4264	IucA IucC family
H1I71_08800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I71_08815	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H1I71_08835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1I71_08840	COG0730	response to heat
H1I71_08860	COG4773	Receptor
H1I71_08865	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I71_08880	COG1131	(ABC) transporter
H1I71_08885	COG0842	Transport permease protein
H1I71_08890	COG0842	Transport permease protein
H1I71_08945	COG2226	methyltransferase
H1I71_08970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1I71_09005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I71_09015	COG0133	tryptophan synthase activity
H1I71_09030	COG3706	GGDEF domain
H1I71_09045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I71_09050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1I71_09055	COG0022	dehydrogenase e1 component
H1I71_09060	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I71_09065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I71_09075	COG1063	alcohol dehydrogenase
H1I71_09080	COG3781	membrane
H1I71_09090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I71_09090	COG3453	Protein conserved in bacteria
H1I71_09100	COG0730	response to heat
H1I71_09115	COG2207	Transcriptional regulator
H1I71_09115	COG3708	Transcriptional regulator
H1I71_09120	COG1733	regulation of RNA biosynthetic process
H1I71_09125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1I71_09135	COG2188	Transcriptional regulator
H1I71_09150	COG4521	taurine ABC transporter
H1I71_09155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I71_09175	COG0477	Major facilitator Superfamily
H1I71_09185	COG1027	Aspartate ammonia-lyase
H1I71_09200	COG0583	DNA-binding transcription factor activity
H1I71_09205	COG0583	DNA-binding transcription factor activity
H1I71_09210	COG0183	Belongs to the thiolase family
H1I71_09215	COG2031	fatty acid transporter
H1I71_09220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I71_09230	COG0583	DNA-binding transcription factor activity
H1I71_09240	COG2610	gluconate transmembrane transporter activity
H1I71_09245	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_09255	COG2207	Transcriptional regulator
H1I71_09270	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_09295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I71_09295	COG0543	2 iron, 2 sulfur cluster binding
H1I71_09300	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I71_09305	COG4638	Rieske (2fe-2S)
H1I71_09315	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1I71_09320	COG4149	molybdate abc transporter
H1I71_09325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1I71_09330	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_09335	COG3433	isochorismatase activity
H1I71_09335	COG1535	isochorismatase
H1I71_09400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I71_09415	COG0753	catalase activity
H1I71_09425	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H1I71_09455	COG3539	Fimbrial protein
H1I71_09475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I71_09495	COG2072	flavoprotein involved in K transport
H1I71_09505	COG1538	Outer membrane efflux protein
H1I71_09510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I71_09515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_09520	COG0745	RESPONSE REGULATOR receiver
H1I71_09525	COG2205	protein histidine kinase activity
H1I71_09540	COG2207	Transcriptional regulator
H1I71_09555	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_09605	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H1I71_09720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I71_09740	COG1120	ATPase activity
H1I71_09745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I71_09755	COG1064	alcohol dehydrogenase
H1I71_09770	COG2207	Transcriptional regulator
H1I71_09775	COG2084	Dehydrogenase
H1I71_09785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1I71_09790	COG0583	DNA-binding transcription factor activity
H1I71_09800	COG0129	dihydroxy-acid dehydratase activity
H1I71_09805	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_09820	COG1566	PFAM secretion protein HlyD family protein
H1I71_09840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I71_09870	COG0583	DNA-binding transcription factor activity
H1I71_09885	COG2188	Transcriptional regulator
H1I71_09915	COG3210	domain, Protein
H1I71_09920	COG2831	hemolysin activation secretion protein
H1I71_09935	COG1473	amidohydrolase
H1I71_09945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I71_09945	COG0475	glutathione-regulated potassium exporter activity
H1I71_09955	COG0583	DNA-binding transcription factor activity
H1I71_09960	COG1335	isochorismatase
H1I71_09970	COG1309	transcriptional regulator
H1I71_10000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1I71_10010	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I71_10010	COG1902	pentaerythritol trinitrate reductase activity
H1I71_10015	COG1846	Transcriptional regulator
H1I71_10035	COG0753	catalase activity
H1I71_10050	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_10065	COG3162	membrane
H1I71_10075	COG3829	transcription factor binding
H1I71_10080	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_10085	COG1960	acyl-CoA dehydrogenase activity
H1I71_10105	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_10125	COG2186	Transcriptional regulator
H1I71_10135	COG0583	DNA-binding transcription factor activity
H1I71_10140	COG4948	Mandelate Racemase Muconate Lactonizing
H1I71_10145	COG4829	muconolactone delta-isomerase
H1I71_10155	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I71_10160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I71_10165	COG0183	Belongs to the thiolase family
H1I71_10170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I71_10180	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_10190	COG3733	amine oxidase
H1I71_10200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I71_10210	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_10220	COG4638	Rieske (2fe-2S)
H1I71_10240	COG0154	amidase activity
H1I71_10250	COG2814	Major facilitator Superfamily
H1I71_10275	COG1960	acyl-CoA dehydrogenase activity
H1I71_10280	COG0583	DNA-binding transcription factor activity
H1I71_10285	COG1414	Transcriptional regulator
H1I71_10300	COG2391	methyltransferase activity
H1I71_10310	COG4993	Dehydrogenase
H1I71_10315	COG3659	wide pore channel activity
H1I71_10320	COG3420	alginic acid biosynthetic process
H1I71_10325	COG0710	3-dehydroquinate dehydratase activity
H1I71_10330	COG3485	protocatechuate 3,4-dioxygenase
H1I71_10335	COG3485	protocatechuate 3,4-dioxygenase
H1I71_10340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I71_10345	COG2271	Major facilitator Superfamily
H1I71_10350	COG0596	Alpha beta hydrolase
H1I71_10355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1I71_10360	COG0183	Belongs to the thiolase family
H1I71_10365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I71_10370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I71_10380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1I71_10385	COG2323	membrane
H1I71_10430	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I71_10430	COG1902	pentaerythritol trinitrate reductase activity
H1I71_10455	COG0542	response to heat
H1I71_10460	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1I71_10490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I71_10495	COG0569	domain protein
H1I71_10500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1I71_10515	COG4774	siderophore transport
H1I71_10520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1I71_10530	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1I71_10545	COG1294	oxidase, subunit
H1I71_10550	COG4890	Cyd operon protein YbgT
H1I71_10565	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H1I71_10575	COG0552	protein localization to endoplasmic reticulum
H1I71_10600	COG0517	IMP dehydrogenase activity
H1I71_10600	COG0516	GMP reductase activity
H1I71_10605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I71_10610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1I71_10620	COG0583	DNA-binding transcription factor activity
H1I71_10625	COG0024	Methionine aminopeptidase
H1I71_10655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1I71_10655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I71_10660	COG1105	Belongs to the carbohydrate kinase PfkB family
H1I71_10665	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1I71_10665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I71_10665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I71_10685	COG5001	Diguanylate cyclase
H1I71_10685	COG3300	MHYT domain
H1I71_10700	COG2135	peptidase activity
H1I71_10705	COG0659	secondary active sulfate transmembrane transporter activity
H1I71_10720	COG1113	amino acid transport
H1I71_10730	COG1522	sequence-specific DNA binding
H1I71_10755	COG1011	Hydrolase
H1I71_10760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1I71_10770	COG2137	regulation of response to DNA damage stimulus
H1I71_10785	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I71_10820	COG0575	Belongs to the CDS family
H1I71_10825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1I71_10845	COG3852	Histidine kinase
H1I71_10850	COG2204	response regulator
H1I71_10915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I71_10920	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1I71_10940	COG0697	spore germination
H1I71_10945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I71_10955	COG0303	'Molybdopterin
H1I71_10960	COG0315	cyclic pyranopterin monophosphate synthase activity
H1I71_10960	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1I71_10975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1I71_10980	COG0243	molybdopterin cofactor binding
H1I71_10990	COG0243	molybdopterin cofactor binding
H1I71_10995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I71_11000	COG2146	nitrite reductase [NAD(P)H] activity
H1I71_11000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I71_11010	COG0745	RESPONSE REGULATOR receiver
H1I71_11015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I71_11015	COG1116	anion transmembrane transporter activity
H1I71_11035	COG0511	ligase activity, forming carbon-carbon bonds
H1I71_11050	COG2814	Major facilitator Superfamily
H1I71_11120	COG1196	nuclear chromosome segregation
H1I71_11120	COG0741	lytic transglycosylase activity
H1I71_11120	COG0739	heme binding
H1I71_11260	COG5410	chromosome segregation
H1I71_11345	COG4197	protein conserved in bacteria, prophage-related
H1I71_11350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I71_11420	COG0069	glutamate synthase activity
H1I71_11440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1I71_11450	COG1454	alcohol dehydrogenase
H1I71_11455	COG0824	Thioesterase
H1I71_11465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1I71_11480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I71_11485	COG2030	dehydratase
H1I71_11495	COG0183	Belongs to the thiolase family
H1I71_11505	COG0583	DNA-binding transcription factor activity
H1I71_11510	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1I71_11520	COG1522	sequence-specific DNA binding
H1I71_11525	COG3135	benzoate transporter
H1I71_11535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1I71_11560	COG0589	response to stress
H1I71_11565	COG0488	(ABC) transporter
H1I71_11585	COG4773	Receptor
H1I71_11620	COG0668	transmembrane transport
H1I71_11630	COG1309	transcriptional regulator
H1I71_11645	COG1605	Chorismate mutase
H1I71_11655	COG4221	oxidoreductase activity
H1I71_11665	COG0308	aminopeptidase N
H1I71_11685	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1I71_11695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I71_11700	COG1454	alcohol dehydrogenase
H1I71_11720	COG0531	amino acid
H1I71_11725	COG4303	Ethanolamine ammonia lyase large subunit
H1I71_11730	COG4302	ethanolamine ammonia-lyase activity
H1I71_11735	COG0519	Catalyzes the synthesis of GMP from XMP
H1I71_11735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I71_11740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I71_11750	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I71_11765	COG0697	spore germination
H1I71_11770	COG1923	regulation of RNA biosynthetic process
H1I71_11780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1I71_11785	COG0802	atpase or kinase
H1I71_11805	COG1187	pseudouridine synthase activity
H1I71_11820	COG0583	DNA-binding transcription factor activity
H1I71_11835	COG2814	Major facilitator Superfamily
H1I71_11840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I71_11865	COG0729	surface antigen
H1I71_11885	COG0174	glutamine synthetase
H1I71_11890	COG0745	RESPONSE REGULATOR receiver
H1I71_11895	COG2205	protein histidine kinase activity
H1I71_11905	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1I71_11910	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1I71_11935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I71_11940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I71_11945	COG1960	acyl-CoA dehydrogenase activity
H1I71_11960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I71_11965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I71_11985	COG0583	DNA-binding transcription factor activity
H1I71_12000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I71_12010	COG3658	cytochrome
H1I71_12015	COG1215	transferase activity, transferring glycosyl groups
H1I71_12020	COG1649	PFAM Uncharacterised BCR, COG1649
H1I71_12020	COG0726	polysaccharide deacetylase
H1I71_12045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1I71_12050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1I71_12060	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1I71_12085	COG0305	Participates in initiation and elongation during chromosome replication
H1I71_12090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1I71_12100	COG1305	Transglutaminase-like
H1I71_12110	COG2308	Evidence 4 Homologs of previously reported genes of
H1I71_12140	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H1I71_12145	COG0138	bifunctional purine biosynthesis protein purh
H1I71_12150	COG0151	Belongs to the GarS family
H1I71_12155	COG1464	Belongs to the NlpA lipoprotein family
H1I71_12160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I71_12165	COG2011	ABC-type metal ion transport system permease component
H1I71_12170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I71_12180	COG1301	dicarboxylic acid transport
H1I71_12230	COG3209	COG3209 Rhs family protein
H1I71_12260	COG4269	membrane
H1I71_12275	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I71_12275	COG1902	pentaerythritol trinitrate reductase activity
H1I71_12285	COG3706	GGDEF domain
H1I71_12285	COG2203	Gaf domain
H1I71_12285	COG5001	Diguanylate cyclase
H1I71_12285	COG4251	negative regulation of phosphorylation
H1I71_12295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I71_12315	COG4172	Belongs to the ABC transporter superfamily
H1I71_12320	COG4239	(ABC) transporter, permease
H1I71_12325	COG4174	ABC transporter (Permease)
H1I71_12335	COG1388	LysM domain
H1I71_12335	COG1388	LysM domain
H1I71_12335	COG0741	lytic transglycosylase activity
H1I71_12335	COG0741	lytic transglycosylase activity
H1I71_12340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I71_12380	COG0583	DNA-binding transcription factor activity
H1I71_12385	COG1279	arginine transmembrane transporter activity
H1I71_12405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I71_12410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I71_12415	COG0006	proline dipeptidase activity
H1I71_12500	COG0741	lytic transglycosylase activity
H1I71_12500	COG0739	heme binding
H1I71_12500	COG1196	nuclear chromosome segregation
H1I71_12560	COG4695	Portal protein
H1I71_12655	COG0305	Participates in initiation and elongation during chromosome replication
H1I71_12670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I71_12720	COG2194	sulfuric ester hydrolase activity
H1I71_12765	COG0739	heme binding
H1I71_13090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1I71_13115	COG3384	dioxygenase
H1I71_13125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I71_13130	COG2878	Part of a membrane complex involved in electron transport
H1I71_13135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1I71_13160	COG0768	penicillin binding
H1I71_13165	COG0742	ribosomal rna small subunit methyltransferase
H1I71_13180	COG0830	nickel cation binding
H1I71_13190	COG0804	urea catabolic process
H1I71_13230	COG1253	flavin adenine dinucleotide binding
H1I71_13235	COG2851	Citrate transporter
H1I71_13285	COG1773	rubredoxin
H1I71_13290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I71_13300	COG0583	DNA-binding transcription factor activity
H1I71_13325	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1I71_13330	COG4181	ATPase activity
H1I71_13375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1I71_13395	COG0306	phosphate transporter
H1I71_13405	COG3958	Transketolase
H1I71_13410	COG3959	Transketolase, thiamine diphosphate binding domain
H1I71_13415	COG2271	Major facilitator Superfamily
H1I71_13420	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_13425	COG0583	DNA-binding transcription factor activity
H1I71_13440	COG2223	nitrite transmembrane transporter activity
H1I71_13445	COG2207	Transcriptional regulator
H1I71_13450	COG2066	Belongs to the glutaminase family
H1I71_13455	COG0242	peptide deformylase activity
H1I71_13460	COG0477	Major facilitator Superfamily
H1I71_13470	COG0028	Belongs to the TPP enzyme family
H1I71_13485	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_13490	COG2267	carboxylic ester hydrolase activity
H1I71_13500	COG2271	Major facilitator Superfamily
H1I71_13505	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I71_13515	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_13535	COG1414	Transcriptional regulator
H1I71_13550	COG1024	Enoyl-CoA hydratase
H1I71_13560	COG1215	transferase activity, transferring glycosyl groups
H1I71_13565	COG1649	PFAM Uncharacterised BCR, COG1649
H1I71_13565	COG0726	polysaccharide deacetylase
H1I71_13575	COG4681	YaeQ
H1I71_13585	COG0523	cobalamin synthesis protein
H1I71_13595	COG1607	acyl-coa hydrolase
H1I71_13605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I71_13610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I71_13615	COG1309	transcriptional regulator
H1I71_13640	COG2040	homocysteine
H1I71_13645	COG0531	amino acid
H1I71_13700	COG1595	DNA-templated transcription, initiation
H1I71_13710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I71_13715	COG0477	Major facilitator Superfamily
H1I71_13735	COG0084	hydrolase, TatD family'
H1I71_13770	COG0629	single-stranded DNA binding
H1I71_13825	COG0582	viral genome integration into host DNA
H1I71_13850	COG1061	Type III restriction enzyme res subunit
H1I71_13860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I71_13865	COG1192	Involved in chromosome partitioning
H1I71_13875	COG1061	Type III restriction enzyme res subunit
H1I71_13960	COG0592	DNA-directed DNA polymerase activity
H1I71_14000	COG2026	Addiction module toxin, RelE StbE family
H1I71_14150	COG3755	Protein conserved in bacteria
H1I71_14195	COG1484	DNA-dependent DNA replication
H1I71_14285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I71_14355	COG0405	Gamma-glutamyltransferase
H1I71_14360	COG2814	Major facilitator Superfamily
H1I71_14370	COG2050	protein possibly involved in aromatic compounds catabolism
H1I71_14385	COG1090	epimerase
H1I71_14405	COG0420	3'-5' exonuclease activity
H1I71_14430	COG0735	belongs to the Fur family
H1I71_14435	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1I71_14455	COG0121	glutamine amidotransferase
H1I71_14470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I71_14480	COG0210	DNA helicase
H1I71_14485	COG2885	chlorophyll binding
H1I71_14490	COG0204	Acyl-transferase
H1I71_14505	COG2894	cell division
H1I71_14530	COG1280	lysine exporter protein (LysE YggA)
H1I71_14535	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1I71_14535	COG1674	ftsk spoiiie
H1I71_14540	COG0492	ferredoxin-NADP+ reductase activity
H1I71_14545	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H1I71_14555	COG0456	acetyltransferase
H1I71_14600	COG1981	membrane
H1I71_14615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I71_14615	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1I71_14635	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_14645	COG0657	acetylesterase activity
H1I71_14655	COG0473	3-isopropylmalate dehydrogenase activity
H1I71_14660	COG0583	DNA-binding transcription factor activity
H1I71_14680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I71_14705	COG0564	pseudouridine synthase activity
H1I71_14715	COG0358	DNA primase activity
H1I71_14730	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H1I71_14760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I71_14790	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1I71_14800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I71_14800	COG0352	thiamine-phosphate diphosphorylase activity
H1I71_14800	COG0351	phosphomethylpyrimidine kinase
H1I71_14805	COG1652	LysM domain
H1I71_14830	COG1399	metal-binding, possibly nucleic acid-binding protein
H1I71_14835	COG3101	peptidyl-lysine hydroxylation
H1I71_14840	COG0009	L-threonylcarbamoyladenylate synthase
H1I71_14845	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H1I71_14850	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H1I71_14865	COG4106	trans-aconitate 2-methyltransferase activity
H1I71_14880	COG2226	methyltransferase
H1I71_14880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I71_14880	COG0596	Alpha beta hydrolase
H1I71_14885	COG1877	trehalose-phosphatase activity
H1I71_14890	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1I71_14895	COG2223	nitrite transmembrane transporter activity
H1I71_14915	COG1196	nuclear chromosome segregation
H1I71_14925	COG0730	response to heat
H1I71_14940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1I71_14950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I71_15010	COG0489	protein tyrosine kinase activity
H1I71_15020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I71_15020	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I71_15050	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H1I71_15055	COG2081	HI0933 family
H1I71_15065	COG0668	transmembrane transport
H1I71_15085	COG0583	DNA-binding transcription factor activity
H1I71_15105	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1I71_15110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I71_15140	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H1I71_15180	COG0745	RESPONSE REGULATOR receiver
H1I71_15200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1I71_15210	COG2205	protein histidine kinase activity
H1I71_15280	COG4993	Dehydrogenase
H1I71_15305	COG0384	phenazine biosynthesis protein PhzF
H1I71_15325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I71_15340	COG0583	DNA-binding transcription factor activity
H1I71_15370	COG0583	DNA-binding transcription factor activity
H1I71_15385	COG0583	DNA-binding transcription factor activity
H1I71_15390	COG1053	succinate dehydrogenase
H1I71_15400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1I71_15405	COG2814	Major facilitator Superfamily
H1I71_15410	COG1960	acyl-CoA dehydrogenase activity
H1I71_15415	COG0583	DNA-binding transcription factor activity
H1I71_15420	COG1063	alcohol dehydrogenase
H1I71_15450	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1I71_15455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1I71_15460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I71_15475	COG3667	copper resistance
H1I71_15480	COG2132	Multicopper oxidase
H1I71_15490	COG0561	phosphatase activity
H1I71_15495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1I71_15520	COG1214	PFAM Peptidase M22, glycoprotease
H1I71_15570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1I71_15580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1I71_15585	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H1I71_15590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1I71_15650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I71_15660	COG1846	Transcriptional regulator
H1I71_15665	COG1764	response to oxidative stress
H1I71_15705	COG0037	tRNA processing
H1I71_15715	COG0248	Ppx GppA phosphatase
H1I71_15745	COG0072	phenylalanine-tRNA ligase activity
H1I71_15785	COG1238	metal cluster binding
H1I71_15790	COG0625	glutathione transferase activity
H1I71_15805	COG0318	PFAM AMP-dependent synthetase and ligase
H1I71_15810	COG3028	Belongs to the UPF0307 family
H1I71_15815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I71_15835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1I71_15840	COG0617	tRNA 3'-terminal CCA addition
H1I71_15845	COG1555	photosystem II stabilization
H1I71_15850	COG3956	TIGRFAM MazG family protein
H1I71_15860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I71_15880	COG5002	protein histidine kinase activity
H1I71_15880	COG0784	Response regulator, receiver
H1I71_15880	COG2205	protein histidine kinase activity
H1I71_15885	COG1024	Enoyl-CoA hydratase
H1I71_15890	COG2084	Dehydrogenase
H1I71_15895	COG3622	Belongs to the hyi family
H1I71_15925	COG0697	spore germination
H1I71_15935	COG2814	Major facilitator Superfamily
H1I71_15940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I71_15950	COG0583	DNA-binding transcription factor activity
H1I71_15960	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1I71_15975	COG0084	hydrolase, TatD family'
H1I71_15990	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1I71_16020	COG0440	acetolactate synthase activity
H1I71_16025	COG0028	Belongs to the TPP enzyme family
H1I71_16050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_16055	COG0577	efflux transmembrane transporter activity
H1I71_16055	COG1136	(ABC) transporter
H1I71_16060	COG1538	Outer membrane efflux protein
H1I71_16075	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H1I71_16080	COG1162	GTPase activity
H1I71_16090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1I71_16110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1I71_16115	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_16155	COG2986	histidine ammonia-lyase
H1I71_16170	COG0318	PFAM AMP-dependent synthetase and ligase
H1I71_16180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I71_16225	COG1426	Protein conserved in bacteria
H1I71_16260	COG0793	Belongs to the peptidase S41A family
H1I71_16275	COG2267	carboxylic ester hydrolase activity
H1I71_16285	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_16290	COG3265	gluconokinase activity
H1I71_16300	COG0800	Aldolase
H1I71_16310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1I71_16315	COG0280	phosphate acetyltransferase
H1I71_16315	COG0857	belongs to the CobB CobQ family
H1I71_16320	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I71_16320	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I71_16340	COG0740	serine-type endopeptidase activity
H1I71_16350	COG4774	siderophore transport
H1I71_16360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1I71_16370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I71_16370	COG2813	Specifically methylates the guanine in position
H1I71_16470	COG0788	formyltetrahydrofolate deformylase activity
H1I71_16495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I71_16495	COG4651	solute:proton antiporter activity
H1I71_16515	COG0724	RNA recognition motif
H1I71_16520	COG0210	DNA helicase
H1I71_16545	COG1733	regulation of RNA biosynthetic process
H1I71_16555	COG2900	Belongs to the SlyX family
H1I71_16560	COG0488	(ABC) transporter
H1I71_16565	COG1280	lysine exporter protein (LysE YggA)
H1I71_16570	COG1560	Kdo2-lipid A biosynthetic process
H1I71_16580	COG1301	dicarboxylic acid transport
H1I71_16635	COG0473	3-isopropylmalate dehydrogenase activity
H1I71_16700	COG0583	DNA-binding transcription factor activity
H1I71_16710	COG0625	glutathione transferase activity
H1I71_16715	COG2378	regulation of single-species biofilm formation
H1I71_16720	COG0546	phosphoglycolate phosphatase activity
H1I71_16730	COG1530	ribonuclease E activity
H1I71_16735	COG0318	PFAM AMP-dependent synthetase and ligase
H1I71_16750	COG0583	DNA-binding transcription factor activity
H1I71_16755	COG4221	oxidoreductase activity
H1I71_16760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1I71_16770	COG0534	Mate efflux family protein
H1I71_16785	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1I71_16825	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1I71_16830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I71_16845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I71_16855	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1I71_16855	COG0644	oxidoreductase
H1I71_16860	COG0425	Belongs to the sulfur carrier protein TusA family
H1I71_16865	COG4535	Mg2 and Co2 transporter CorC
H1I71_16875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I71_16895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1I71_16900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I71_16900	COG0475	glutathione-regulated potassium exporter activity
H1I71_16905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H1I71_16915	COG0484	heat shock protein binding
H1I71_16920	COG0789	Transcriptional regulator
H1I71_16925	COG0598	Magnesium transport protein CorA
H1I71_16940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I71_16945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I71_16950	COG1074	ATP-dependent DNA helicase activity
H1I71_16955	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1I71_16975	COG2226	methyltransferase
H1I71_16990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I71_16995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H1I71_17010	COG2111	Na H antiporter
H1I71_17010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I71_17015	COG1006	Multisubunit Na H antiporter MnhC subunit
H1I71_17020	COG0651	ATP synthesis coupled electron transport
H1I71_17025	COG1863	multisubunit Na H antiporter MnhE subunit
H1I71_17030	COG2212	antiporter activity
H1I71_17035	COG1320	monovalent cation:proton antiporter activity
H1I71_17050	COG0195	Participates in both transcription termination and antitermination
H1I71_17100	COG0237	dephospho-CoA kinase activity
H1I71_17110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I71_17125	COG0497	DNA recombination
H1I71_17135	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1I71_17165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I71_17165	COG2169	Transcriptional regulator
H1I71_17170	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1I71_17235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1I71_17250	COG0326	Molecular chaperone. Has ATPase activity
H1I71_17265	COG2056	Na+-H+ antiporter family
H1I71_17270	COG0596	Alpha beta hydrolase
H1I71_17365	COG0546	phosphoglycolate phosphatase activity
H1I71_17370	COG1716	ATPase activity
H1I71_17415	COG0181	hydroxymethylbilane synthase activity
H1I71_17425	COG3275	phosphorelay sensor kinase activity
H1I71_17445	COG1538	Outer membrane efflux protein
H1I71_17450	COG0697	spore germination
H1I71_17475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I71_17480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1I71_17485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I71_17490	COG0772	Belongs to the SEDS family
H1I71_17515	COG4974	Belongs to the 'phage' integrase family
H1I71_17520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I71_17530	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1I71_17540	COG2197	response regulator
H1I71_17555	COG0793	Belongs to the peptidase S41A family
H1I71_17560	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1I71_17565	COG0795	lipopolysaccharide-transporting ATPase activity
H1I71_17605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I71_17605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I71_17615	COG0004	ammonium transporteR
H1I71_17620	COG0347	Belongs to the P(II) protein family
H1I71_17630	COG0606	chelatase, subunit chli
H1I71_17685	COG0659	secondary active sulfate transmembrane transporter activity
H1I71_17690	COG0589	response to stress
H1I71_17720	COG0606	chelatase, subunit chli
H1I71_17725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I71_17735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I71_17750	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1I71_17765	COG0318	PFAM AMP-dependent synthetase and ligase
H1I71_17775	COG0477	Major facilitator Superfamily
H1I71_17780	COG2860	membrane
H1I71_17790	COG1253	flavin adenine dinucleotide binding
H1I71_17810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1I71_17845	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1I71_17855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1I71_17890	COG1309	transcriptional regulator
H1I71_17925	COG0758	DNA mediated transformation
H1I71_17935	COG0697	spore germination
H1I71_17940	COG1309	transcriptional regulator
H1I71_17955	COG0386	Belongs to the glutathione peroxidase family
H1I71_18020	COG1121	(ABC) transporter
H1I71_18025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1I71_18030	COG1280	lysine exporter protein (LysE YggA)
H1I71_18035	COG2837	iron assimilation
H1I71_18045	COG0281	malic enzyme
H1I71_18090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I71_18090	COG0519	Catalyzes the synthesis of GMP from XMP
H1I71_18095	COG4399	Belongs to the UPF0754 family
H1I71_18100	COG2259	Doxx family
H1I71_18105	COG0586	Pfam SNARE associated Golgi protein
H1I71_18120	COG1192	Involved in chromosome partitioning
H1I71_18130	COG0271	Belongs to the BolA IbaG family
H1I71_18145	COG2267	carboxylic ester hydrolase activity
H1I71_18165	COG3321	synthase
H1I71_18165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I71_18165	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1I71_18165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1I71_18170	COG1960	acyl-CoA dehydrogenase activity
H1I71_18180	COG2197	response regulator
H1I71_18190	COG3916	Acyl-homoserine-lactone synthase
H1I71_18195	COG0477	Major facilitator Superfamily
H1I71_18200	COG1024	Enoyl-CoA hydratase
H1I71_18205	COG1024	Enoyl-CoA hydratase
H1I71_18210	COG1960	acyl-CoA dehydrogenase activity
H1I71_18215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I71_18235	COG1113	amino acid transport
H1I71_18240	COG1113	amino acid transport
H1I71_18245	COG0251	oxidation-reduction process
H1I71_18285	COG0564	pseudouridine synthase activity
H1I71_18345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1I71_18360	COG1802	Transcriptional regulator
H1I71_18370	COG1448	Aminotransferase
H1I71_18375	COG0277	FAD linked oxidase domain protein
H1I71_18385	COG2186	Transcriptional regulator
H1I71_18395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I71_18400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I71_18415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1I71_18420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1I71_18425	COG1216	Glycosyl transferase, family 2
H1I71_18455	COG2089	acid synthase
H1I71_18470	COG1083	cytidylyl-transferase
H1I71_18475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1I71_18480	COG1086	Polysaccharide biosynthesis protein
H1I71_18485	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1I71_18490	COG1596	polysaccharide export
H1I71_18515	COG0728	peptidoglycan biosynthetic process
H1I71_18520	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1I71_18575	COG0546	phosphoglycolate phosphatase activity
H1I71_18580	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_18600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I71_18605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I71_18610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I71_18615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I71_18620	COG1116	anion transmembrane transporter activity
H1I71_18625	COG1309	transcriptional regulator
H1I71_18630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1I71_18640	COG0196	riboflavin kinase activity
H1I71_18645	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1I71_18655	COG1047	Peptidyl-prolyl cis-trans
H1I71_18695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1I71_18700	COG0657	acetylesterase activity
H1I71_18750	COG2951	lytic endotransglycosylase activity
H1I71_18755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1I71_18770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1I71_18780	COG0671	phosphoesterase, PA-phosphatase related
H1I71_18785	COG0861	Integral membrane protein TerC family
H1I71_18795	COG0754	glutathionylspermidine amidase activity
H1I71_18805	COG0402	S-adenosylhomocysteine deaminase activity
H1I71_18820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I71_18825	COG1230	cation diffusion facilitator family transporter
H1I71_18840	COG0706	membrane insertase activity