locus-tag	class	description
H1I68_00010	COG0592	DNA-directed DNA polymerase activity
H1I68_00020	COG0187	DNA topoisomerase II activity
H1I68_00030	COG0586	Pfam SNARE associated Golgi protein
H1I68_00035	COG0488	(ABC) transporter
H1I68_00060	COG0596	Alpha beta hydrolase
H1I68_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1I68_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1I68_00110	COG0733	neurotransmitter:sodium symporter activity
H1I68_00145	COG0583	DNA-binding transcription factor activity
H1I68_00150	COG2233	PERMEase
H1I68_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I68_00200	COG2814	Major facilitator Superfamily
H1I68_00205	COG0656	L-ascorbic acid biosynthetic process
H1I68_00210	COG0583	DNA-binding transcription factor activity
H1I68_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I68_00230	COG1064	alcohol dehydrogenase
H1I68_00235	COG2818	Glycosylase
H1I68_00250	COG1194	a g-specific adenine glycosylase
H1I68_00270	COG2983	Belongs to the UPF0260 family
H1I68_00275	COG2133	pyrroloquinoline quinone binding
H1I68_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1I68_00285	COG2116	formate transmembrane transporter activity
H1I68_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I68_00310	COG1335	isochorismatase
H1I68_00315	COG0385	Bile acid
H1I68_00325	COG1683	Conserved Protein
H1I68_00345	COG0625	glutathione transferase activity
H1I68_00355	COG1113	amino acid transport
H1I68_00365	COG0523	cobalamin synthesis protein
H1I68_00375	COG2188	Transcriptional regulator
H1I68_00405	COG0010	Belongs to the arginase family
H1I68_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I68_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1I68_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1I68_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1I68_00540	COG0534	Mate efflux family protein
H1I68_00545	COG0436	Aminotransferase
H1I68_00550	COG2733	membrane
H1I68_00565	COG2918	glutathione biosynthetic process
H1I68_00580	COG1388	LysM domain
H1I68_00580	COG0791	NLP P60 protein
H1I68_00600	COG3150	esterase
H1I68_00610	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_00615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H1I68_00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I68_00635	COG2233	PERMEase
H1I68_00640	COG2351	hydroxyisourate hydrolase activity
H1I68_00675	COG3706	GGDEF domain
H1I68_00690	COG1393	Belongs to the ArsC family
H1I68_00695	COG0708	Exodeoxyribonuclease III
H1I68_00715	COG0189	ligase activity
H1I68_00735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1I68_00745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1I68_00760	COG4942	peptidase
H1I68_00770	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I68_00780	COG2119	membrane
H1I68_00855	COG3267	Type II secretory pathway component ExeA
H1I68_00855	COG3409	Peptidoglycan-binding domain 1 protein
H1I68_00885	COG0681	Belongs to the peptidase S26 family
H1I68_00920	COG4373	Mu-like prophage FluMu protein gp28
H1I68_00935	COG4383	Mu-like prophage protein gp29
H1I68_00940	COG2369	cell adhesion
H1I68_00945	COG5005	Phage virion morphogenesis
H1I68_00960	COG4397	Mu-like prophage major head subunit gpT
H1I68_01055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I68_01055	COG0426	domain, Protein
H1I68_01080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1I68_01100	COG1902	pentaerythritol trinitrate reductase activity
H1I68_01115	COG0668	transmembrane transport
H1I68_01125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I68_01130	COG1335	isochorismatase
H1I68_01135	COG1522	sequence-specific DNA binding
H1I68_01165	COG1061	Type III restriction enzyme res subunit
H1I68_01190	COG2205	protein histidine kinase activity
H1I68_01190	COG2198	Histidine kinase
H1I68_01190	COG0784	Response regulator, receiver
H1I68_01195	COG3162	membrane
H1I68_01200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I68_01210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I68_01230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1I68_01235	COG1309	transcriptional regulator
H1I68_01255	COG0352	thiamine-phosphate diphosphorylase activity
H1I68_01255	COG0351	phosphomethylpyrimidine kinase
H1I68_01255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I68_01265	COG2814	Major facilitator Superfamily
H1I68_01280	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I68_01290	COG1113	amino acid transport
H1I68_01300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I68_01305	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_01315	COG1335	isochorismatase
H1I68_01345	COG2814	Major facilitator Superfamily
H1I68_01350	COG0583	DNA-binding transcription factor activity
H1I68_01370	COG0667	Aldo Keto reductase
H1I68_01400	COG1733	regulation of RNA biosynthetic process
H1I68_01405	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I68_01470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1I68_01485	COG2329	Antibiotic biosynthesis monooxygenase
H1I68_01515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1I68_01545	COG0427	acetyl-CoA hydrolase
H1I68_01570	COG0659	secondary active sulfate transmembrane transporter activity
H1I68_01575	COG4221	oxidoreductase activity
H1I68_01580	COG2873	o-acetylhomoserine
H1I68_01585	COG0488	(ABC) transporter
H1I68_01670	COG0833	amino acid
H1I68_01715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1I68_01720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1I68_01735	COG2226	methyltransferase
H1I68_01785	COG0067	glutamate synthase
H1I68_01785	COG0070	glutamate synthase
H1I68_01785	COG0069	glutamate synthase activity
H1I68_01790	COG0493	'glutamate synthase
H1I68_01800	COG1704	LemA family
H1I68_01805	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1I68_01825	COG3307	-O-antigen
H1I68_01845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I68_01860	COG0194	GDP metabolic process
H1I68_01910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1I68_01930	COG5380	lipid catabolic process
H1I68_01935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1I68_01960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1I68_01965	COG0277	FAD linked oxidase domain protein
H1I68_01975	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1I68_01980	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I68_01995	COG1289	transmembrane transporter activity
H1I68_02005	COG0628	permease
H1I68_02010	COG1192	Involved in chromosome partitioning
H1I68_02040	COG0833	amino acid
H1I68_02045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I68_02050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I68_02060	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_02100	COG0583	DNA-binding transcription factor activity
H1I68_02145	COG0517	IMP dehydrogenase activity
H1I68_02150	COG1983	PspC domain protein
H1I68_02160	COG1960	acyl-CoA dehydrogenase activity
H1I68_02175	COG0408	coproporphyrinogen oxidase activity
H1I68_02195	COG0513	Belongs to the DEAD box helicase family
H1I68_02205	COG1127	ABC transporter
H1I68_02210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1I68_02220	COG2854	intermembrane phospholipid transfer
H1I68_02230	COG0598	Magnesium transport protein CorA
H1I68_02240	COG0494	nUDIX hydrolase
H1I68_02245	COG1040	competence protein
H1I68_02250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1I68_02270	COG1946	Acyl-CoA thioesterase
H1I68_02275	COG1301	dicarboxylic acid transport
H1I68_02290	COG1959	2 iron, 2 sulfur cluster binding
H1I68_02295	COG1017	nitric oxide dioxygenase activity
H1I68_02295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I68_02300	COG0433	COG0433 Predicted ATPase
H1I68_02305	COG0626	cystathionine gamma-synthase activity
H1I68_02460	COG1960	acyl-CoA dehydrogenase activity
H1I68_02465	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1I68_02495	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1I68_02500	COG0339	signal peptide processing
H1I68_02505	COG0557	exoribonuclease II activity
H1I68_02550	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1I68_02555	COG2169	Transcriptional regulator
H1I68_02560	COG0697	spore germination
H1I68_02565	COG1295	ribonuclease BN
H1I68_02600	COG1702	phosphate starvation-inducible protein PhoH
H1I68_02610	COG1196	nuclear chromosome segregation
H1I68_02610	COG0739	heme binding
H1I68_02610	COG0741	lytic transglycosylase activity
H1I68_02640	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1I68_02645	COG1183	phosphatidylcholine synthase activity
H1I68_02690	COG1960	acyl-CoA dehydrogenase activity
H1I68_02695	COG1309	transcriptional regulator
H1I68_02710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I68_02715	COG1960	acyl-CoA dehydrogenase activity
H1I68_02735	COG2969	positive regulation of protein catabolic process
H1I68_02745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1I68_02760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1I68_02765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1I68_02785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1I68_02795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I68_02800	COG1408	metallophosphoesterase
H1I68_02810	COG2199	diguanylate cyclase activity
H1I68_02870	COG1607	acyl-coa hydrolase
H1I68_02900	COG2350	Protein conserved in bacteria
H1I68_02910	COG0613	PHP domain protein
H1I68_02915	COG3781	membrane
H1I68_02925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1I68_02930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1I68_02940	COG1862	Preprotein translocase
H1I68_02970	COG2205	protein histidine kinase activity
H1I68_02975	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H1I68_02995	COG0726	polysaccharide deacetylase
H1I68_03000	COG0463	Glycosyl transferase, family 2
H1I68_03005	COG0438	transferase activity, transferring glycosyl groups
H1I68_03070	COG0625	glutathione transferase activity
H1I68_03075	COG0583	DNA-binding transcription factor activity
H1I68_03080	COG1960	acyl-CoA dehydrogenase activity
H1I68_03085	COG1960	acyl-CoA dehydrogenase activity
H1I68_03095	COG2205	protein histidine kinase activity
H1I68_03100	COG0745	RESPONSE REGULATOR receiver
H1I68_03105	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H1I68_03125	COG2096	Adenosyltransferase
H1I68_03175	COG0285	dihydrofolate synthase activity
H1I68_03195	COG0450	alkyl hydroperoxide reductase
H1I68_03215	COG1272	protein, Hemolysin III
H1I68_03240	COG1024	Enoyl-CoA hydratase
H1I68_03240	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I68_03245	COG0183	Belongs to the thiolase family
H1I68_03250	COG2207	Transcriptional regulator
H1I68_03270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I68_03290	COG0183	Belongs to the thiolase family
H1I68_03300	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1I68_03300	COG2885	chlorophyll binding
H1I68_03310	COG1690	Belongs to the RtcB family
H1I68_03315	COG0833	amino acid
H1I68_03325	COG2233	PERMEase
H1I68_03330	COG1217	gtp-binding protein TYPA
H1I68_03355	COG2094	Belongs to the DNA glycosylase MPG family
H1I68_03360	COG4772	TonB-dependent receptor
H1I68_03375	COG1902	pentaerythritol trinitrate reductase activity
H1I68_03380	COG0679	Auxin Efflux Carrier
H1I68_03390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I68_03395	COG0354	folic acid binding
H1I68_03405	COG3189	MarR family transcriptional regulator
H1I68_03410	COG2824	Alkylphosphonate utilization operon protein PhnA
H1I68_03415	COG3422	double-strand break repair
H1I68_03455	COG0840	transmembrane signaling receptor activity
H1I68_03475	COG5510	response to toxic substance
H1I68_03485	COG2832	Protein of unknown function (DUF454)
H1I68_03490	COG1376	ErfK ybiS ycfS ynhG family protein
H1I68_03530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1I68_03540	COG1289	transmembrane transporter activity
H1I68_03545	COG2814	Major facilitator Superfamily
H1I68_03565	COG1115	amino acid carrier protein
H1I68_03570	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I68_03575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I68_03580	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1I68_03610	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I68_03620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I68_03625	COG1077	Cell shape determining protein MreB Mrl
H1I68_03630	COG1792	Involved in formation and maintenance of cell shape
H1I68_03635	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1I68_03640	COG0424	maF-like protein
H1I68_03645	COG1530	ribonuclease E activity
H1I68_03655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I68_03665	COG0560	Phosphoserine phosphatase
H1I68_03675	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I68_03700	COG2207	Transcriptional regulator
H1I68_04100	COG0582	viral genome integration into host DNA
H1I68_04110	COG1113	amino acid transport
H1I68_04115	COG2828	Protein conserved in bacteria
H1I68_04120	COG0142	geranyltranstransferase activity
H1I68_04125	COG2315	Protein conserved in bacteria
H1I68_04140	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I68_04160	COG2194	sulfuric ester hydrolase activity
H1I68_04165	COG0745	RESPONSE REGULATOR receiver
H1I68_04170	COG0642	Histidine kinase
H1I68_04180	COG0004	ammonium transporteR
H1I68_04185	COG0583	DNA-binding transcription factor activity
H1I68_04205	COG0525	valine-tRNA ligase activity
H1I68_04215	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_04225	COG0393	Putative heavy-metal-binding
H1I68_04230	COG0393	Putative heavy-metal-binding
H1I68_04235	COG1538	Outer membrane efflux protein
H1I68_04245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I68_04250	COG0671	phosphoesterase, PA-phosphatase related
H1I68_04280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1I68_04295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1I68_04295	COG1648	precorrin-2 dehydrogenase activity
H1I68_04300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1I68_04305	COG1733	regulation of RNA biosynthetic process
H1I68_04315	COG0531	amino acid
H1I68_04330	COG0321	lipoyl(octanoyl) transferase activity
H1I68_04335	COG2921	Belongs to the UPF0250 family
H1I68_04375	COG2009	succinate dehydrogenase
H1I68_04380	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1I68_04385	COG1053	succinate dehydrogenase
H1I68_04390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1I68_04415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I68_04435	COG2354	Protein conserved in bacteria
H1I68_04440	COG2321	neutral zinc metallopeptidase
H1I68_04500	COG2843	Capsule synthesis protein
H1I68_04515	COG0589	response to stress
H1I68_04535	COG0505	Belongs to the CarA family
H1I68_04560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I68_04565	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1I68_04615	COG0477	Major facilitator Superfamily
H1I68_04620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1I68_04635	COG1597	lipid kinase activity
H1I68_04640	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I68_04680	COG0584	glycerophosphoryl diester phosphodiesterase
H1I68_04700	COG0741	lytic transglycosylase activity
H1I68_04720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1I68_04735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I68_04760	COG0778	Nitroreductase
H1I68_04775	COG1929	Belongs to the glycerate kinase type-1 family
H1I68_04780	COG0243	molybdopterin cofactor binding
H1I68_04785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1I68_04790	COG3339	Conserved Protein
H1I68_04800	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H1I68_04815	COG1113	amino acid transport
H1I68_04825	COG0019	diaminopimelate decarboxylase activity
H1I68_04835	COG1280	lysine exporter protein (LysE YggA)
H1I68_04840	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I68_04870	COG0463	Glycosyl transferase, family 2
H1I68_04890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I68_04925	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1I68_04930	COG1136	(ABC) transporter
H1I68_04935	COG0658	competence protein
H1I68_04935	COG2333	competence protein COMEC
H1I68_04945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1I68_04945	COG0616	signal peptide processing
H1I68_04950	COG0596	Alpha beta hydrolase
H1I68_04955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1I68_04965	COG0628	permease
H1I68_05000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I68_05020	COG0823	Involved in the tonB-independent uptake of proteins
H1I68_05040	COG0824	Thioesterase
H1I68_05045	COG1473	amidohydrolase
H1I68_05065	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1I68_05065	COG0047	phosphoribosylformylglycinamidine synthase activity
H1I68_05070	COG2814	Major facilitator Superfamily
H1I68_05080	COG1024	Enoyl-CoA hydratase
H1I68_05085	COG1051	belongs to the nudix hydrolase family
H1I68_05085	COG1056	cytidyltransferase-related domain
H1I68_05095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1I68_05110	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1I68_05125	COG4625	pathogenesis
H1I68_05130	COG0583	DNA-binding transcription factor activity
H1I68_05135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1I68_05140	COG4208	sulfate ABC transporter
H1I68_05145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1I68_05155	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1I68_05160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1I68_05165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1I68_05185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I68_05200	COG0681	Belongs to the peptidase S26 family
H1I68_05215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1I68_05225	COG1381	Involved in DNA repair and RecF pathway recombination
H1I68_05230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1I68_05240	COG4221	oxidoreductase activity
H1I68_05270	COG0436	Aminotransferase
H1I68_05290	COG0556	nucleotide-excision repair
H1I68_05345	COG2070	2-Nitropropane dioxygenase
H1I68_05375	COG1215	transferase activity, transferring glycosyl groups
H1I68_05390	COG0415	Belongs to the DNA photolyase family
H1I68_05400	COG1252	NADH dehydrogenase
H1I68_05405	COG1686	Belongs to the peptidase S11 family
H1I68_05420	COG1187	pseudouridine synthase activity
H1I68_05445	COG0477	Major facilitator Superfamily
H1I68_05450	COG0583	DNA-binding transcription factor activity
H1I68_05455	COG1823	symporter activity
H1I68_05465	COG0612	Peptidase, M16
H1I68_05490	COG0352	thiamine-phosphate diphosphorylase activity
H1I68_05525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I68_05540	COG1309	transcriptional regulator
H1I68_05550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I68_05555	COG0076	glutamate decarboxylase activity
H1I68_05565	COG1522	sequence-specific DNA binding
H1I68_05570	COG3961	Belongs to the TPP enzyme family
H1I68_05575	COG1113	amino acid transport
H1I68_05580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I68_05585	COG0573	inorganic phosphate transmembrane transporter activity
H1I68_05595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1I68_05600	COG0616	signal peptide processing
H1I68_05635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1I68_05640	COG1686	Belongs to the peptidase S11 family
H1I68_05665	COG0583	DNA-binding transcription factor activity
H1I68_05670	COG1067	ATP-dependent peptidase activity
H1I68_05715	COG1966	Carbon starvation protein
H1I68_05720	COG2879	small protein
H1I68_05750	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1I68_05750	COG2508	Transcriptional regulator
H1I68_05770	COG1113	amino acid transport
H1I68_05775	COG0583	DNA-binding transcription factor activity
H1I68_05780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I68_05785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I68_05795	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_05800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I68_05805	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H1I68_05805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I68_05840	COG2814	Major facilitator Superfamily
H1I68_05845	COG4948	Mandelate Racemase Muconate Lactonizing
H1I68_05855	COG1309	transcriptional regulator
H1I68_05875	COG1741	Belongs to the pirin family
H1I68_05885	COG2964	Protein conserved in bacteria
H1I68_05900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I68_05905	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I68_05910	COG4605	iron ion homeostasis
H1I68_05915	COG4604	ABC transporter, ATP-binding protein
H1I68_05920	COG4607	ABC-type enterochelin transport system periplasmic component
H1I68_05925	COG4774	siderophore transport
H1I68_05935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I68_05940	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1I68_05945	COG1535	isochorismatase
H1I68_05945	COG3433	isochorismatase activity
H1I68_05960	COG1132	(ABC) transporter
H1I68_05965	COG1132	(ABC) transporter
H1I68_05970	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H1I68_05980	COG1169	isochorismate synthase
H1I68_05995	COG3739	integral membrane protein
H1I68_06020	COG0302	gtp cyclohydrolase
H1I68_06030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1I68_06060	COG0308	aminopeptidase N
H1I68_06065	COG0512	Glutamine amidotransferase of anthranilate synthase
H1I68_06255	COG5410	chromosome segregation
H1I68_06425	COG0582	viral genome integration into host DNA
H1I68_06440	COG0174	glutamine synthetase
H1I68_06450	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H1I68_06485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1I68_06490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1I68_06495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I68_06515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I68_06520	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1I68_06525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1I68_06540	COG1960	acyl-CoA dehydrogenase activity
H1I68_06545	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I68_06550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I68_06560	COG2223	nitrite transmembrane transporter activity
H1I68_06570	COG0024	Methionine aminopeptidase
H1I68_06575	COG0052	Belongs to the universal ribosomal protein uS2 family
H1I68_06590	COG2207	Transcriptional regulator
H1I68_06615	COG2951	lytic endotransglycosylase activity
H1I68_06620	COG0772	Belongs to the SEDS family
H1I68_06635	COG0842	Transport permease protein
H1I68_06640	COG1131	(ABC) transporter
H1I68_06685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I68_06700	COG4215	(ABC) transporter
H1I68_06705	COG4160	amino acid transport
H1I68_06710	COG4598	ABC transporter
H1I68_06720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I68_06725	COG0826	peptidase U32
H1I68_06730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I68_06745	COG1720	tRNA m6t6A37 methyltransferase activity
H1I68_06755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1I68_06770	COG0642	Histidine kinase
H1I68_06780	COG0494	nUDIX hydrolase
H1I68_06790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1I68_06795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1I68_06800	COG3139	Protein of unknown function (DUF1315)
H1I68_06805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1I68_06810	COG1301	dicarboxylic acid transport
H1I68_06815	COG1960	acyl-CoA dehydrogenase activity
H1I68_06820	COG2819	hydrolase of the alpha beta superfamily
H1I68_06830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1I68_06840	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1I68_06845	COG1234	tRNA 3'-trailer cleavage
H1I68_06875	COG2363	Small membrane protein
H1I68_06895	COG0513	Belongs to the DEAD box helicase family
H1I68_06905	COG0778	Nitroreductase
H1I68_06935	COG1286	toxin biosynthetic process
H1I68_06960	COG4783	chaperone-mediated protein folding
H1I68_06965	COG1610	YqeY-like protein
H1I68_07065	COG3111	PFAM Bacterial OB fold (BOF) protein
H1I68_07090	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1I68_07095	COG0786	glutamate:sodium symporter activity
H1I68_07105	COG2186	Transcriptional regulator
H1I68_07155	COG0477	Major facilitator Superfamily
H1I68_07180	COG2985	domain, Protein
H1I68_07190	COG2995	paraquat-inducible protein a
H1I68_07195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1I68_07195	COG3008	intermembrane lipid transfer
H1I68_07205	COG1794	racemase activity, acting on amino acids and derivatives
H1I68_07290	COG0482	sulfurtransferase activity
H1I68_07305	COG0488	(ABC) transporter
H1I68_07310	COG3173	Aminoglycoside phosphotransferase
H1I68_07320	COG2433	Pfam Transposase IS66
H1I68_07360	COG1301	dicarboxylic acid transport
H1I68_07370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I68_07375	COG2011	ABC-type metal ion transport system permease component
H1I68_07380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I68_07385	COG1464	Belongs to the NlpA lipoprotein family
H1I68_07390	COG0151	Belongs to the GarS family
H1I68_07395	COG0138	bifunctional purine biosynthesis protein purh
H1I68_07400	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H1I68_07430	COG2308	Evidence 4 Homologs of previously reported genes of
H1I68_07440	COG1305	Transglutaminase-like
H1I68_07450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1I68_07455	COG0305	Participates in initiation and elongation during chromosome replication
H1I68_07480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1I68_07490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1I68_07495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1I68_07520	COG0726	polysaccharide deacetylase
H1I68_07520	COG1649	PFAM Uncharacterised BCR, COG1649
H1I68_07525	COG1215	transferase activity, transferring glycosyl groups
H1I68_07530	COG3658	cytochrome
H1I68_07540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I68_07555	COG0583	DNA-binding transcription factor activity
H1I68_07575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I68_07580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I68_07595	COG1960	acyl-CoA dehydrogenase activity
H1I68_07600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I68_07605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I68_07630	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1I68_07635	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1I68_07645	COG2205	protein histidine kinase activity
H1I68_07650	COG0745	RESPONSE REGULATOR receiver
H1I68_07655	COG0174	glutamine synthetase
H1I68_07675	COG0729	surface antigen
H1I68_07700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I68_07705	COG2814	Major facilitator Superfamily
H1I68_07720	COG0583	DNA-binding transcription factor activity
H1I68_07735	COG1187	pseudouridine synthase activity
H1I68_07755	COG0802	atpase or kinase
H1I68_07760	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1I68_07770	COG1923	regulation of RNA biosynthetic process
H1I68_07775	COG0697	spore germination
H1I68_07790	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I68_07800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I68_07805	COG0519	Catalyzes the synthesis of GMP from XMP
H1I68_07805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I68_07810	COG4302	ethanolamine ammonia-lyase activity
H1I68_07815	COG4303	Ethanolamine ammonia lyase large subunit
H1I68_07820	COG0531	amino acid
H1I68_07840	COG1454	alcohol dehydrogenase
H1I68_07845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I68_07855	COG3708	Transcriptional regulator
H1I68_07855	COG2207	Transcriptional regulator
H1I68_07875	COG0308	aminopeptidase N
H1I68_07885	COG4221	oxidoreductase activity
H1I68_07895	COG1605	Chorismate mutase
H1I68_07910	COG1309	transcriptional regulator
H1I68_07920	COG0668	transmembrane transport
H1I68_07955	COG4773	Receptor
H1I68_07975	COG0488	(ABC) transporter
H1I68_07980	COG0589	response to stress
H1I68_08005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1I68_08015	COG3135	benzoate transporter
H1I68_08020	COG1522	sequence-specific DNA binding
H1I68_08030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1I68_08035	COG0583	DNA-binding transcription factor activity
H1I68_08045	COG0183	Belongs to the thiolase family
H1I68_08055	COG2030	dehydratase
H1I68_08060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I68_08075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1I68_08085	COG0824	Thioesterase
H1I68_08090	COG1454	alcohol dehydrogenase
H1I68_08100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1I68_08120	COG0069	glutamate synthase activity
H1I68_08140	COG2814	Major facilitator Superfamily
H1I68_08155	COG0511	ligase activity, forming carbon-carbon bonds
H1I68_08175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I68_08175	COG1116	anion transmembrane transporter activity
H1I68_08180	COG0745	RESPONSE REGULATOR receiver
H1I68_08190	COG2146	nitrite reductase [NAD(P)H] activity
H1I68_08190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I68_08195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I68_08200	COG0243	molybdopterin cofactor binding
H1I68_08210	COG0243	molybdopterin cofactor binding
H1I68_08215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1I68_08230	COG0315	cyclic pyranopterin monophosphate synthase activity
H1I68_08230	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1I68_08235	COG0303	'Molybdopterin
H1I68_08245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I68_08250	COG0697	spore germination
H1I68_08270	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1I68_08275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I68_08330	COG2204	response regulator
H1I68_08335	COG3852	Histidine kinase
H1I68_08355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1I68_08360	COG0575	Belongs to the CDS family
H1I68_08395	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I68_08410	COG2137	regulation of response to DNA damage stimulus
H1I68_08420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1I68_08425	COG1011	Hydrolase
H1I68_08450	COG1522	sequence-specific DNA binding
H1I68_08460	COG1113	amino acid transport
H1I68_08475	COG0659	secondary active sulfate transmembrane transporter activity
H1I68_08480	COG2135	peptidase activity
H1I68_08495	COG3300	MHYT domain
H1I68_08495	COG5001	Diguanylate cyclase
H1I68_08515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I68_08515	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1I68_08515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I68_08520	COG1105	Belongs to the carbohydrate kinase PfkB family
H1I68_08525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1I68_08525	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I68_08555	COG0024	Methionine aminopeptidase
H1I68_08560	COG0583	DNA-binding transcription factor activity
H1I68_08570	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1I68_08575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I68_08580	COG0517	IMP dehydrogenase activity
H1I68_08580	COG0516	GMP reductase activity
H1I68_08605	COG0552	protein localization to endoplasmic reticulum
H1I68_08615	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H1I68_08630	COG4890	Cyd operon protein YbgT
H1I68_08635	COG1294	oxidase, subunit
H1I68_08650	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1I68_08660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1I68_08665	COG4774	siderophore transport
H1I68_08680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1I68_08685	COG0569	domain protein
H1I68_08690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I68_08720	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1I68_08725	COG0542	response to heat
H1I68_08750	COG1902	pentaerythritol trinitrate reductase activity
H1I68_08750	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I68_08795	COG2323	membrane
H1I68_08800	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1I68_08810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I68_08815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I68_08820	COG0183	Belongs to the thiolase family
H1I68_08825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1I68_08830	COG0596	Alpha beta hydrolase
H1I68_08835	COG2271	Major facilitator Superfamily
H1I68_08840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I68_08845	COG3485	protocatechuate 3,4-dioxygenase
H1I68_08850	COG3485	protocatechuate 3,4-dioxygenase
H1I68_08855	COG0710	3-dehydroquinate dehydratase activity
H1I68_08860	COG3420	alginic acid biosynthetic process
H1I68_08865	COG3659	wide pore channel activity
H1I68_08870	COG4993	Dehydrogenase
H1I68_08880	COG2391	methyltransferase activity
H1I68_08895	COG1414	Transcriptional regulator
H1I68_08900	COG0583	DNA-binding transcription factor activity
H1I68_08905	COG1960	acyl-CoA dehydrogenase activity
H1I68_08930	COG2814	Major facilitator Superfamily
H1I68_08940	COG0154	amidase activity
H1I68_08960	COG4638	Rieske (2fe-2S)
H1I68_08970	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_08980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I68_08990	COG3733	amine oxidase
H1I68_09000	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_09010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I68_09015	COG0183	Belongs to the thiolase family
H1I68_09020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I68_09025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I68_09035	COG4829	muconolactone delta-isomerase
H1I68_09040	COG4948	Mandelate Racemase Muconate Lactonizing
H1I68_09045	COG0583	DNA-binding transcription factor activity
H1I68_09055	COG2186	Transcriptional regulator
H1I68_09075	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_09095	COG1960	acyl-CoA dehydrogenase activity
H1I68_09100	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_09105	COG3829	transcription factor binding
H1I68_09115	COG3162	membrane
H1I68_09130	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_09145	COG0753	catalase activity
H1I68_09165	COG1846	Transcriptional regulator
H1I68_09170	COG1902	pentaerythritol trinitrate reductase activity
H1I68_09170	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I68_09180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1I68_09210	COG1309	transcriptional regulator
H1I68_09220	COG1335	isochorismatase
H1I68_09225	COG0583	DNA-binding transcription factor activity
H1I68_09235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I68_09235	COG0475	glutathione-regulated potassium exporter activity
H1I68_09245	COG1473	amidohydrolase
H1I68_09255	COG2831	hemolysin activation secretion protein
H1I68_09260	COG3210	domain, Protein
H1I68_09290	COG2188	Transcriptional regulator
H1I68_09305	COG0583	DNA-binding transcription factor activity
H1I68_09335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I68_09355	COG1566	PFAM secretion protein HlyD family protein
H1I68_09370	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_09375	COG0129	dihydroxy-acid dehydratase activity
H1I68_09385	COG0583	DNA-binding transcription factor activity
H1I68_09400	COG2084	Dehydrogenase
H1I68_09405	COG2207	Transcriptional regulator
H1I68_09420	COG1064	alcohol dehydrogenase
H1I68_09430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I68_09435	COG1120	ATPase activity
H1I68_09455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I68_09570	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H1I68_09620	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_09635	COG2207	Transcriptional regulator
H1I68_09645	COG2205	protein histidine kinase activity
H1I68_09650	COG0745	RESPONSE REGULATOR receiver
H1I68_09655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I68_09660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I68_09665	COG1538	Outer membrane efflux protein
H1I68_09675	COG2072	flavoprotein involved in K transport
H1I68_09695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I68_09715	COG3539	Fimbrial protein
H1I68_09745	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H1I68_09755	COG0753	catalase activity
H1I68_09770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I68_09835	COG1535	isochorismatase
H1I68_09835	COG3433	isochorismatase activity
H1I68_09840	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_09845	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1I68_09850	COG4149	molybdate abc transporter
H1I68_09855	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1I68_09870	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I68_09875	COG0543	2 iron, 2 sulfur cluster binding
H1I68_09875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I68_09900	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_09915	COG2207	Transcriptional regulator
H1I68_09925	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_09930	COG2610	gluconate transmembrane transporter activity
H1I68_09940	COG0583	DNA-binding transcription factor activity
H1I68_09950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I68_09955	COG2031	fatty acid transporter
H1I68_09960	COG0183	Belongs to the thiolase family
H1I68_09965	COG0583	DNA-binding transcription factor activity
H1I68_09970	COG0583	DNA-binding transcription factor activity
H1I68_09985	COG1027	Aspartate ammonia-lyase
H1I68_09995	COG0477	Major facilitator Superfamily
H1I68_10015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I68_10020	COG4521	taurine ABC transporter
H1I68_10035	COG2188	Transcriptional regulator
H1I68_10045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1I68_10050	COG1733	regulation of RNA biosynthetic process
H1I68_10055	COG2207	Transcriptional regulator
H1I68_10055	COG3708	Transcriptional regulator
H1I68_10070	COG0730	response to heat
H1I68_10080	COG3453	Protein conserved in bacteria
H1I68_10080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I68_10090	COG3781	membrane
H1I68_10095	COG1063	alcohol dehydrogenase
H1I68_10105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I68_10110	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I68_10120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1I68_10125	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I68_10140	COG3706	GGDEF domain
H1I68_10155	COG0133	tryptophan synthase activity
H1I68_10165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I68_10200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1I68_10225	COG2226	methyltransferase
H1I68_10280	COG0842	Transport permease protein
H1I68_10285	COG0842	Transport permease protein
H1I68_10290	COG1131	(ABC) transporter
H1I68_10305	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I68_10310	COG4773	Receptor
H1I68_10330	COG0730	response to heat
H1I68_10335	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1I68_10355	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H1I68_10370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I68_10410	COG4264	IucA IucC family
H1I68_10415	COG4264	IucA IucC family
H1I68_10435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1I68_10450	COG1960	acyl-CoA dehydrogenase activity
H1I68_10455	COG1960	acyl-CoA dehydrogenase activity
H1I68_10460	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I68_10465	COG2207	Transcriptional regulator
H1I68_10470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I68_10475	COG0776	regulation of translation
H1I68_10500	COG0822	iron-sulfur transferase activity
H1I68_10505	COG0316	Belongs to the HesB IscA family
H1I68_10535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1I68_10555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I68_10560	COG0702	epimerase
H1I68_10595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1I68_10605	COG0339	signal peptide processing
H1I68_10655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1I68_10660	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1I68_10690	COG0776	regulation of translation
H1I68_10755	COG0084	hydrolase, TatD family'
H1I68_10775	COG1663	tetraacyldisaccharide 4'-kinase activity
H1I68_10780	COG1132	(ABC) transporter
H1I68_10790	COG0811	peptide transport
H1I68_10795	COG1475	DNA binding
H1I68_10800	COG1192	Involved in chromosome partitioning
H1I68_10810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1I68_10825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I68_10830	COG0191	fructose-bisphosphate aldolase activity
H1I68_10850	COG0424	maF-like protein
H1I68_10855	COG2850	peptidyl-arginine hydroxylation
H1I68_10865	COG0640	Transcriptional regulator
H1I68_10875	COG3619	membrane
H1I68_10880	COG3122	Protein conserved in bacteria
H1I68_10885	COG1132	(ABC) transporter
H1I68_10905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1I68_10910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I68_10920	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I68_10920	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I68_10920	COG0506	proline dehydrogenase activity
H1I68_10925	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H1I68_10940	COG3698	Phosphodiester glycosidase
H1I68_10950	COG2353	YceI-like domain
H1I68_10960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1I68_11030	COG3539	Fimbrial protein
H1I68_11035	COG3121	Chaperone
H1I68_11060	COG0697	spore germination
H1I68_11070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I68_11080	COG0583	DNA-binding transcription factor activity
H1I68_11100	COG1309	transcriptional regulator
H1I68_11115	COG1522	sequence-specific DNA binding
H1I68_11125	COG1126	abc transporter atp-binding protein
H1I68_11130	COG0765	amino acid transport
H1I68_11135	COG0765	amino acid transport
H1I68_11165	COG1464	Belongs to the NlpA lipoprotein family
H1I68_11175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I68_11180	COG2011	ABC-type metal ion transport system permease component
H1I68_11185	COG0012	GTP binding
H1I68_11250	COG0386	Belongs to the glutathione peroxidase family
H1I68_11260	COG0436	Aminotransferase
H1I68_11300	COG3634	alkyl hydroperoxide reductase activity
H1I68_11315	COG0583	DNA-binding transcription factor activity
H1I68_11320	COG0798	PFAM Bile acid sodium symporter
H1I68_11325	COG0640	Transcriptional regulator
H1I68_11340	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1I68_11350	COG0583	DNA-binding transcription factor activity
H1I68_11360	COG1953	Uracil, thiamine, allantoin
H1I68_11370	COG2175	clavaminate synthase activity
H1I68_11375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I68_11380	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1I68_11385	COG4521	taurine ABC transporter
H1I68_11395	COG0477	Major facilitator Superfamily
H1I68_11415	COG1271	oxidase subunit
H1I68_11420	COG1294	oxidase, subunit
H1I68_11430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I68_11450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1I68_11470	COG3052	prosthetic group binding
H1I68_11475	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H1I68_11485	COG2814	Major facilitator Superfamily
H1I68_11505	COG1346	cytolysis
H1I68_11515	COG0583	DNA-binding transcription factor activity
H1I68_11520	COG0625	glutathione transferase activity
H1I68_11525	COG0625	glutathione transferase activity
H1I68_11530	COG0583	DNA-binding transcription factor activity
H1I68_11550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I68_11555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1I68_11565	COG1280	lysine exporter protein (LysE YggA)
H1I68_11580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I68_11585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I68_11590	COG1126	abc transporter atp-binding protein
H1I68_11595	COG0765	amino acid transport
H1I68_11600	COG0765	amino acid transport
H1I68_11620	COG0784	Response regulator, receiver
H1I68_11620	COG2205	protein histidine kinase activity
H1I68_11640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I68_11660	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_11710	COG0583	DNA-binding transcription factor activity
H1I68_11730	COG0318	PFAM AMP-dependent synthetase and ligase
H1I68_11735	COG1309	transcriptional regulator
H1I68_11740	COG1960	acyl-CoA dehydrogenase activity
H1I68_11745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I68_11750	COG1024	Enoyl-CoA hydratase
H1I68_11755	COG4770	biotin carboxylase activity
H1I68_11765	COG0583	DNA-binding transcription factor activity
H1I68_11780	COG1960	acyl-CoA dehydrogenase activity
H1I68_11790	COG2814	Major facilitator Superfamily
H1I68_11800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I68_11805	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I68_11810	COG2814	Major facilitator Superfamily
H1I68_11815	COG1960	acyl-CoA dehydrogenase activity
H1I68_11820	COG1024	Enoyl-CoA hydratase
H1I68_11825	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_11830	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I68_11835	COG0183	Belongs to the thiolase family
H1I68_11845	COG2814	Major facilitator Superfamily
H1I68_11855	COG1024	Enoyl-CoA hydratase
H1I68_11870	COG1960	acyl-CoA dehydrogenase activity
H1I68_11875	COG2814	Major facilitator Superfamily
H1I68_11880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I68_11885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H1I68_11900	COG3842	ATPase activity
H1I68_11905	COG1840	ABC-type Fe3 transport system, periplasmic component
H1I68_11930	COG1414	Transcriptional regulator
H1I68_11940	COG0583	DNA-binding transcription factor activity
H1I68_11945	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I68_11950	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_11960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I68_11970	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_11975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I68_11980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I68_11985	COG2267	carboxylic ester hydrolase activity
H1I68_12005	COG3038	cytochrome b561
H1I68_12010	COG0753	catalase activity
H1I68_12045	COG2050	protein possibly involved in aromatic compounds catabolism
H1I68_12055	COG3327	negative regulation of DNA-templated transcription, initiation
H1I68_12060	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H1I68_12065	COG0183	Belongs to the thiolase family
H1I68_12070	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I68_12075	COG1024	Enoyl-CoA hydratase
H1I68_12080	COG1024	Enoyl-CoA hydratase
H1I68_12085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I68_12090	COG2151	metal-sulfur cluster biosynthetic enzyme
H1I68_12095	COG3396	Phenylacetate-CoA oxygenase
H1I68_12100	COG3460	Phenylacetate-CoA oxygenase
H1I68_12105	COG3396	Phenylacetate-CoA oxygenase
H1I68_12110	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_12110	COG2030	dehydratase
H1I68_12115	COG1760	l-serine dehydratase
H1I68_12120	COG0531	amino acid
H1I68_12125	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_12140	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I68_12150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I68_12170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I68_12180	COG0789	Transcriptional regulator
H1I68_12195	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1I68_12210	COG2807	transmembrane transport
H1I68_12215	COG0590	tRNA wobble adenosine to inosine editing
H1I68_12330	COG1116	anion transmembrane transporter activity
H1I68_12335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I68_12345	COG0864	Transcriptional regulator
H1I68_12365	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I68_12370	COG0439	Biotin carboxylase
H1I68_12385	COG1063	alcohol dehydrogenase
H1I68_12395	COG1309	transcriptional regulator
H1I68_12415	COG0038	chloride channel
H1I68_12420	COG4770	biotin carboxylase activity
H1I68_12440	COG1914	H( )-stimulated, divalent metal cation uptake system
H1I68_12445	COG0583	DNA-binding transcription factor activity
H1I68_12495	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I68_12515	COG2814	Major facilitator Superfamily
H1I68_12525	COG1560	Kdo2-lipid A biosynthetic process
H1I68_12535	COG5006	permease, DMT superfamily
H1I68_12540	COG1522	sequence-specific DNA binding
H1I68_12555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1I68_12565	COG4122	O-methyltransferase activity
H1I68_12595	COG1538	Outer membrane efflux protein
H1I68_12600	COG1137	ATPase activity
H1I68_12605	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1I68_12615	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1I68_12620	COG0517	IMP dehydrogenase activity
H1I68_12620	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1I68_12655	COG2814	Major facilitator Superfamily
H1I68_12690	COG1278	Cold shock
H1I68_12695	COG1280	lysine exporter protein (LysE YggA)
H1I68_12725	COG1570	exodeoxyribonuclease VII activity
H1I68_12775	COG0583	DNA-binding transcription factor activity
H1I68_12780	COG4638	Rieske (2fe-2S)
H1I68_12785	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I68_12790	COG0633	Ferredoxin
H1I68_12790	COG0543	2 iron, 2 sulfur cluster binding
H1I68_12795	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_12800	COG3135	benzoate transporter
H1I68_12805	COG2814	Major facilitator Superfamily
H1I68_12820	COG1643	Atp-dependent helicase
H1I68_12825	COG0450	alkyl hydroperoxide reductase
H1I68_12835	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1I68_12845	COG3634	alkyl hydroperoxide reductase activity
H1I68_12865	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1I68_12870	COG0625	glutathione transferase activity
H1I68_12880	COG2885	chlorophyll binding
H1I68_12915	COG0542	response to heat
H1I68_12930	COG1765	OsmC-like protein
H1I68_12945	COG0667	Aldo Keto reductase
H1I68_12960	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1I68_12970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1I68_12980	COG0527	aspartate kinase activity
H1I68_12990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1I68_13000	COG3038	cytochrome b561
H1I68_13005	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1I68_13010	COG2252	PERMEase
H1I68_13020	COG2072	flavoprotein involved in K transport
H1I68_13035	COG1741	Belongs to the pirin family
H1I68_13040	COG1309	transcriptional regulator
H1I68_13095	COG1113	amino acid transport
H1I68_13115	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_13135	COG0531	amino acid
H1I68_13145	COG1113	amino acid transport
H1I68_13185	COG3209	COG3209 Rhs family protein
H1I68_13215	COG4269	membrane
H1I68_13240	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I68_13240	COG1902	pentaerythritol trinitrate reductase activity
H1I68_13250	COG3706	GGDEF domain
H1I68_13250	COG2203	Gaf domain
H1I68_13250	COG5001	Diguanylate cyclase
H1I68_13250	COG4251	negative regulation of phosphorylation
H1I68_13260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I68_13280	COG4172	Belongs to the ABC transporter superfamily
H1I68_13285	COG4239	(ABC) transporter, permease
H1I68_13290	COG4174	ABC transporter (Permease)
H1I68_13300	COG0741	lytic transglycosylase activity
H1I68_13300	COG0741	lytic transglycosylase activity
H1I68_13300	COG1388	LysM domain
H1I68_13300	COG1388	LysM domain
H1I68_13305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I68_13345	COG0583	DNA-binding transcription factor activity
H1I68_13350	COG1279	arginine transmembrane transporter activity
H1I68_13370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I68_13375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I68_13380	COG0006	proline dipeptidase activity
H1I68_13465	COG0739	heme binding
H1I68_13465	COG1196	nuclear chromosome segregation
H1I68_13465	COG0741	lytic transglycosylase activity
H1I68_13525	COG4695	Portal protein
H1I68_13620	COG0305	Participates in initiation and elongation during chromosome replication
H1I68_13635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I68_13690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1I68_13715	COG3384	dioxygenase
H1I68_13725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I68_13730	COG2878	Part of a membrane complex involved in electron transport
H1I68_13735	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1I68_13760	COG0768	penicillin binding
H1I68_13765	COG0742	ribosomal rna small subunit methyltransferase
H1I68_13780	COG0830	nickel cation binding
H1I68_13790	COG0804	urea catabolic process
H1I68_13830	COG1253	flavin adenine dinucleotide binding
H1I68_13835	COG2851	Citrate transporter
H1I68_13885	COG1773	rubredoxin
H1I68_13890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I68_13900	COG0583	DNA-binding transcription factor activity
H1I68_13925	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1I68_13930	COG4181	ATPase activity
H1I68_13975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1I68_13995	COG0306	phosphate transporter
H1I68_14005	COG3958	Transketolase
H1I68_14010	COG3959	Transketolase, thiamine diphosphate binding domain
H1I68_14015	COG2271	Major facilitator Superfamily
H1I68_14020	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_14025	COG0583	DNA-binding transcription factor activity
H1I68_14040	COG2223	nitrite transmembrane transporter activity
H1I68_14045	COG2207	Transcriptional regulator
H1I68_14050	COG2066	Belongs to the glutaminase family
H1I68_14055	COG0242	peptide deformylase activity
H1I68_14060	COG0477	Major facilitator Superfamily
H1I68_14070	COG0028	Belongs to the TPP enzyme family
H1I68_14085	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_14090	COG2267	carboxylic ester hydrolase activity
H1I68_14100	COG2271	Major facilitator Superfamily
H1I68_14105	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I68_14115	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_14135	COG1414	Transcriptional regulator
H1I68_14150	COG1024	Enoyl-CoA hydratase
H1I68_14160	COG1215	transferase activity, transferring glycosyl groups
H1I68_14165	COG1649	PFAM Uncharacterised BCR, COG1649
H1I68_14165	COG0726	polysaccharide deacetylase
H1I68_14175	COG4681	YaeQ
H1I68_14185	COG0523	cobalamin synthesis protein
H1I68_14195	COG1607	acyl-coa hydrolase
H1I68_14205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I68_14210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I68_14215	COG1309	transcriptional regulator
H1I68_14240	COG2040	homocysteine
H1I68_14245	COG0531	amino acid
H1I68_14300	COG1595	DNA-templated transcription, initiation
H1I68_14310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I68_14315	COG0477	Major facilitator Superfamily
H1I68_14425	COG0592	DNA-directed DNA polymerase activity
H1I68_14465	COG2026	Addiction module toxin, RelE StbE family
H1I68_14615	COG3755	Protein conserved in bacteria
H1I68_14660	COG1484	DNA-dependent DNA replication
H1I68_14750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I68_14820	COG0405	Gamma-glutamyltransferase
H1I68_14825	COG2814	Major facilitator Superfamily
H1I68_14835	COG2050	protein possibly involved in aromatic compounds catabolism
H1I68_14850	COG1090	epimerase
H1I68_14870	COG0420	3'-5' exonuclease activity
H1I68_14895	COG0735	belongs to the Fur family
H1I68_14900	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1I68_14920	COG0121	glutamine amidotransferase
H1I68_14935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I68_14945	COG0210	DNA helicase
H1I68_14950	COG2885	chlorophyll binding
H1I68_14955	COG0204	Acyl-transferase
H1I68_14970	COG2894	cell division
H1I68_14990	COG1280	lysine exporter protein (LysE YggA)
H1I68_14995	COG1674	ftsk spoiiie
H1I68_14995	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1I68_15000	COG0492	ferredoxin-NADP+ reductase activity
H1I68_15005	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H1I68_15015	COG0456	acetyltransferase
H1I68_15060	COG1981	membrane
H1I68_15075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I68_15075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1I68_15095	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_15105	COG0657	acetylesterase activity
H1I68_15115	COG0473	3-isopropylmalate dehydrogenase activity
H1I68_15120	COG0583	DNA-binding transcription factor activity
H1I68_15140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I68_15165	COG0564	pseudouridine synthase activity
H1I68_15175	COG0358	DNA primase activity
H1I68_15190	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H1I68_15220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I68_15250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1I68_15260	COG0352	thiamine-phosphate diphosphorylase activity
H1I68_15260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I68_15260	COG0351	phosphomethylpyrimidine kinase
H1I68_15265	COG1652	LysM domain
H1I68_15290	COG1399	metal-binding, possibly nucleic acid-binding protein
H1I68_15295	COG3101	peptidyl-lysine hydroxylation
H1I68_15300	COG0009	L-threonylcarbamoyladenylate synthase
H1I68_15305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H1I68_15310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H1I68_15325	COG4106	trans-aconitate 2-methyltransferase activity
H1I68_15340	COG2226	methyltransferase
H1I68_15340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I68_15340	COG0596	Alpha beta hydrolase
H1I68_15345	COG1877	trehalose-phosphatase activity
H1I68_15350	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1I68_15355	COG2223	nitrite transmembrane transporter activity
H1I68_15375	COG1196	nuclear chromosome segregation
H1I68_15385	COG0730	response to heat
H1I68_15400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1I68_15410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I68_15460	COG0489	protein tyrosine kinase activity
H1I68_15470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I68_15470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I68_15500	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H1I68_15505	COG2081	HI0933 family
H1I68_15515	COG0668	transmembrane transport
H1I68_15535	COG0583	DNA-binding transcription factor activity
H1I68_15555	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1I68_15560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I68_15590	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H1I68_15630	COG0745	RESPONSE REGULATOR receiver
H1I68_15650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1I68_15660	COG2205	protein histidine kinase activity
H1I68_15730	COG4993	Dehydrogenase
H1I68_15755	COG0384	phenazine biosynthesis protein PhzF
H1I68_15775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I68_15790	COG0583	DNA-binding transcription factor activity
H1I68_15820	COG0583	DNA-binding transcription factor activity
H1I68_15835	COG0583	DNA-binding transcription factor activity
H1I68_15840	COG1053	succinate dehydrogenase
H1I68_15850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1I68_15855	COG2814	Major facilitator Superfamily
H1I68_15860	COG1960	acyl-CoA dehydrogenase activity
H1I68_15865	COG0583	DNA-binding transcription factor activity
H1I68_15870	COG1063	alcohol dehydrogenase
H1I68_15900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1I68_15905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1I68_15910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I68_15925	COG3667	copper resistance
H1I68_15930	COG2132	Multicopper oxidase
H1I68_15940	COG0561	phosphatase activity
H1I68_15945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1I68_15970	COG1214	PFAM Peptidase M22, glycoprotease
H1I68_16020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1I68_16030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1I68_16035	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H1I68_16040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1I68_16095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I68_16105	COG1846	Transcriptional regulator
H1I68_16110	COG1764	response to oxidative stress
H1I68_16150	COG0037	tRNA processing
H1I68_16160	COG0248	Ppx GppA phosphatase
H1I68_16190	COG0072	phenylalanine-tRNA ligase activity
H1I68_16230	COG1238	metal cluster binding
H1I68_16235	COG0625	glutathione transferase activity
H1I68_16250	COG0318	PFAM AMP-dependent synthetase and ligase
H1I68_16255	COG3028	Belongs to the UPF0307 family
H1I68_16260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I68_16280	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1I68_16285	COG0617	tRNA 3'-terminal CCA addition
H1I68_16290	COG1555	photosystem II stabilization
H1I68_16295	COG3956	TIGRFAM MazG family protein
H1I68_16305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I68_16325	COG0784	Response regulator, receiver
H1I68_16325	COG5002	protein histidine kinase activity
H1I68_16325	COG2205	protein histidine kinase activity
H1I68_16330	COG1024	Enoyl-CoA hydratase
H1I68_16335	COG2084	Dehydrogenase
H1I68_16340	COG3622	Belongs to the hyi family
H1I68_16370	COG0697	spore germination
H1I68_16380	COG2814	Major facilitator Superfamily
H1I68_16385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I68_16395	COG0583	DNA-binding transcription factor activity
H1I68_16405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1I68_16420	COG0084	hydrolase, TatD family'
H1I68_16435	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1I68_16465	COG0440	acetolactate synthase activity
H1I68_16470	COG0028	Belongs to the TPP enzyme family
H1I68_16495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I68_16500	COG1136	(ABC) transporter
H1I68_16500	COG0577	efflux transmembrane transporter activity
H1I68_16505	COG1538	Outer membrane efflux protein
H1I68_16520	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H1I68_16525	COG1162	GTPase activity
H1I68_16535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1I68_16555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1I68_16560	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_16600	COG2986	histidine ammonia-lyase
H1I68_16615	COG0318	PFAM AMP-dependent synthetase and ligase
H1I68_16625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I68_16670	COG1426	Protein conserved in bacteria
H1I68_16705	COG0793	Belongs to the peptidase S41A family
H1I68_16720	COG2267	carboxylic ester hydrolase activity
H1I68_16730	COG1012	belongs to the aldehyde dehydrogenase family
H1I68_16735	COG3265	gluconokinase activity
H1I68_16745	COG0800	Aldolase
H1I68_16755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1I68_16760	COG0857	belongs to the CobB CobQ family
H1I68_16760	COG0280	phosphate acetyltransferase
H1I68_16765	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I68_16765	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I68_16785	COG0740	serine-type endopeptidase activity
H1I68_16795	COG4774	siderophore transport
H1I68_16805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1I68_16815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I68_16815	COG2813	Specifically methylates the guanine in position
H1I68_16915	COG0788	formyltetrahydrofolate deformylase activity
H1I68_16940	COG4651	solute:proton antiporter activity
H1I68_16940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I68_16960	COG0724	RNA recognition motif
H1I68_16965	COG0210	DNA helicase
H1I68_16990	COG1733	regulation of RNA biosynthetic process
H1I68_17000	COG2900	Belongs to the SlyX family
H1I68_17005	COG0488	(ABC) transporter
H1I68_17010	COG1280	lysine exporter protein (LysE YggA)
H1I68_17015	COG1560	Kdo2-lipid A biosynthetic process
H1I68_17025	COG1301	dicarboxylic acid transport
H1I68_17080	COG0473	3-isopropylmalate dehydrogenase activity
H1I68_17145	COG0583	DNA-binding transcription factor activity
H1I68_17155	COG0625	glutathione transferase activity
H1I68_17160	COG2378	regulation of single-species biofilm formation
H1I68_17165	COG0546	phosphoglycolate phosphatase activity
H1I68_17175	COG1530	ribonuclease E activity
H1I68_17180	COG0318	PFAM AMP-dependent synthetase and ligase
H1I68_17195	COG0583	DNA-binding transcription factor activity
H1I68_17200	COG4221	oxidoreductase activity
H1I68_17205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1I68_17215	COG0534	Mate efflux family protein
H1I68_17230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1I68_17270	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1I68_17275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I68_17290	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I68_17300	COG0644	oxidoreductase
H1I68_17300	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1I68_17305	COG0425	Belongs to the sulfur carrier protein TusA family
H1I68_17310	COG4535	Mg2 and Co2 transporter CorC
H1I68_17320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I68_17340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1I68_17345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I68_17345	COG0475	glutathione-regulated potassium exporter activity
H1I68_17350	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H1I68_17360	COG0484	heat shock protein binding
H1I68_17365	COG0789	Transcriptional regulator
H1I68_17370	COG0598	Magnesium transport protein CorA
H1I68_17385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I68_17390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I68_17395	COG1074	ATP-dependent DNA helicase activity
H1I68_17400	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1I68_17420	COG2226	methyltransferase
H1I68_17435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I68_17440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H1I68_17455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I68_17455	COG2111	Na H antiporter
H1I68_17460	COG1006	Multisubunit Na H antiporter MnhC subunit
H1I68_17465	COG0651	ATP synthesis coupled electron transport
H1I68_17470	COG1863	multisubunit Na H antiporter MnhE subunit
H1I68_17475	COG2212	antiporter activity
H1I68_17480	COG1320	monovalent cation:proton antiporter activity
H1I68_17495	COG0195	Participates in both transcription termination and antitermination
H1I68_17545	COG0237	dephospho-CoA kinase activity
H1I68_17555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I68_17570	COG0497	DNA recombination
H1I68_17580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1I68_17610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I68_17610	COG2169	Transcriptional regulator
H1I68_17615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1I68_17680	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1I68_17710	COG2056	Na+-H+ antiporter family
H1I68_17715	COG0596	Alpha beta hydrolase
H1I68_17815	COG0546	phosphoglycolate phosphatase activity
H1I68_17820	COG1716	ATPase activity
H1I68_17865	COG0181	hydroxymethylbilane synthase activity
H1I68_17875	COG3275	phosphorelay sensor kinase activity
H1I68_17895	COG1538	Outer membrane efflux protein
H1I68_17900	COG0697	spore germination
H1I68_17925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I68_17930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1I68_17935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I68_17940	COG0772	Belongs to the SEDS family
H1I68_17965	COG4974	Belongs to the 'phage' integrase family
H1I68_17970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I68_17980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1I68_17990	COG2197	response regulator
H1I68_18005	COG0793	Belongs to the peptidase S41A family
H1I68_18010	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1I68_18015	COG0795	lipopolysaccharide-transporting ATPase activity
H1I68_18055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I68_18055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I68_18065	COG0004	ammonium transporteR
H1I68_18070	COG0347	Belongs to the P(II) protein family
H1I68_18080	COG0606	chelatase, subunit chli
H1I68_18140	COG0659	secondary active sulfate transmembrane transporter activity
H1I68_18145	COG0589	response to stress
H1I68_18235	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I68_18270	COG0659	secondary active sulfate transmembrane transporter activity
H1I68_18275	COG0589	response to stress
H1I68_18305	COG0606	chelatase, subunit chli
H1I68_18310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I68_18320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I68_18335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1I68_18350	COG0318	PFAM AMP-dependent synthetase and ligase
H1I68_18360	COG0477	Major facilitator Superfamily
H1I68_18365	COG2860	membrane
H1I68_18375	COG1253	flavin adenine dinucleotide binding
H1I68_18395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1I68_18430	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1I68_18440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1I68_18475	COG1309	transcriptional regulator
H1I68_18510	COG0758	DNA mediated transformation
H1I68_18520	COG0697	spore germination
H1I68_18525	COG1309	transcriptional regulator
H1I68_18540	COG0386	Belongs to the glutathione peroxidase family
H1I68_18605	COG1121	(ABC) transporter
H1I68_18610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1I68_18615	COG1280	lysine exporter protein (LysE YggA)
H1I68_18620	COG2837	iron assimilation
H1I68_18630	COG0281	malic enzyme
H1I68_18675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I68_18675	COG0519	Catalyzes the synthesis of GMP from XMP
H1I68_18680	COG4399	Belongs to the UPF0754 family
H1I68_18685	COG2259	Doxx family
H1I68_18690	COG0586	Pfam SNARE associated Golgi protein
H1I68_18705	COG1192	Involved in chromosome partitioning
H1I68_18715	COG0271	Belongs to the BolA IbaG family
H1I68_18735	COG2267	carboxylic ester hydrolase activity
H1I68_18755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I68_18755	COG4221	oxidoreductase activity
H1I68_18755	COG3321	synthase
H1I68_18755	COG0300	oxidoreductase activity
H1I68_18760	COG1960	acyl-CoA dehydrogenase activity
H1I68_18770	COG2197	response regulator
H1I68_18780	COG3916	Acyl-homoserine-lactone synthase
H1I68_18785	COG0477	Major facilitator Superfamily
H1I68_18790	COG1024	Enoyl-CoA hydratase
H1I68_18795	COG1024	Enoyl-CoA hydratase
H1I68_18800	COG1960	acyl-CoA dehydrogenase activity
H1I68_18805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I68_18825	COG1113	amino acid transport
H1I68_18830	COG1113	amino acid transport
H1I68_18835	COG0251	oxidation-reduction process
H1I68_18875	COG0564	pseudouridine synthase activity
H1I68_18920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1I68_18935	COG1802	Transcriptional regulator
H1I68_18945	COG1448	Aminotransferase
H1I68_18950	COG0277	FAD linked oxidase domain protein
H1I68_18960	COG2186	Transcriptional regulator
H1I68_18970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I68_18975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I68_18990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1I68_18995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1I68_19020	COG2244	polysaccharide biosynthetic process
H1I68_19025	COG1083	cytidylyl-transferase
H1I68_19030	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1I68_19040	COG2089	acid synthase
H1I68_19045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H1I68_19050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1I68_19060	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1I68_19065	COG1596	polysaccharide export
H1I68_19090	COG0728	peptidoglycan biosynthetic process
H1I68_19095	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1I68_19150	COG0546	phosphoglycolate phosphatase activity
H1I68_19155	COG1028	Short-chain dehydrogenase reductase Sdr
H1I68_19175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I68_19180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I68_19185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I68_19190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I68_19195	COG1116	anion transmembrane transporter activity
H1I68_19200	COG1309	transcriptional regulator
H1I68_19205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1I68_19215	COG0196	riboflavin kinase activity
H1I68_19220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1I68_19230	COG1047	Peptidyl-prolyl cis-trans
H1I68_19270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1I68_19275	COG0657	acetylesterase activity
H1I68_19325	COG2951	lytic endotransglycosylase activity
H1I68_19330	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1I68_19345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1I68_19355	COG0671	phosphoesterase, PA-phosphatase related
H1I68_19360	COG0861	Integral membrane protein TerC family
H1I68_19370	COG0754	glutathionylspermidine amidase activity
H1I68_19380	COG0402	S-adenosylhomocysteine deaminase activity
H1I68_19410	COG1230	cation diffusion facilitator family transporter
H1I68_19425	COG0706	membrane insertase activity