locus-tag	class	description
N4T38_00010	COG0592	DNA-directed DNA polymerase activity
N4T38_00020	COG0187	DNA topoisomerase II activity
N4T38_00030	COG0586	Pfam SNARE associated Golgi protein
N4T38_00035	COG0488	(ABC) transporter
N4T38_00060	COG0596	Alpha beta hydrolase
N4T38_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
N4T38_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N4T38_00110	COG0733	neurotransmitter:sodium symporter activity
N4T38_00145	COG0583	DNA-binding transcription factor activity
N4T38_00150	COG2233	PERMEase
N4T38_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T38_00200	COG2814	Major facilitator Superfamily
N4T38_00205	COG0656	L-ascorbic acid biosynthetic process
N4T38_00210	COG0583	DNA-binding transcription factor activity
N4T38_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T38_00230	COG1064	alcohol dehydrogenase
N4T38_00235	COG2818	Glycosylase
N4T38_00250	COG1194	a g-specific adenine glycosylase
N4T38_00270	COG2983	Belongs to the UPF0260 family
N4T38_00290	COG1335	isochorismatase
N4T38_00295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T38_00315	COG2116	formate transmembrane transporter activity
N4T38_00320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N4T38_00415	COG0534	Mate efflux family protein
N4T38_00420	COG1683	Conserved Protein
N4T38_00440	COG0625	glutathione transferase activity
N4T38_00450	COG1113	amino acid transport
N4T38_00460	COG0523	cobalamin synthesis protein
N4T38_00470	COG2188	Transcriptional regulator
N4T38_00500	COG0010	Belongs to the arginase family
N4T38_00515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N4T38_00520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N4T38_00530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N4T38_00535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N4T38_00620	COG0534	Mate efflux family protein
N4T38_00625	COG0436	Aminotransferase
N4T38_00630	COG2733	membrane
N4T38_00645	COG2918	glutathione biosynthetic process
N4T38_00690	COG3150	esterase
N4T38_00700	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
N4T38_00710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T38_00720	COG2233	PERMEase
N4T38_00725	COG2351	hydroxyisourate hydrolase activity
N4T38_00760	COG3706	GGDEF domain
N4T38_00775	COG1393	Belongs to the ArsC family
N4T38_00780	COG0708	Exodeoxyribonuclease III
N4T38_00795	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N4T38_00815	COG0189	ligase activity
N4T38_00835	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N4T38_00845	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N4T38_00860	COG4942	peptidase
N4T38_00870	COG0508	dehydrogenase complex catalyzes the overall conversion of
N4T38_00880	COG2119	membrane
N4T38_00885	COG4774	siderophore transport
N4T38_00890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T38_00890	COG0426	domain, Protein
N4T38_00915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N4T38_00935	COG1902	pentaerythritol trinitrate reductase activity
N4T38_00940	COG1519	Transferase
N4T38_00945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N4T38_00950	COG0668	transmembrane transport
N4T38_00960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N4T38_00965	COG1335	isochorismatase
N4T38_00970	COG1522	sequence-specific DNA binding
N4T38_00995	COG0784	Response regulator, receiver
N4T38_00995	COG2198	Histidine kinase
N4T38_00995	COG2205	protein histidine kinase activity
N4T38_01000	COG3162	membrane
N4T38_01005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N4T38_01030	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N4T38_01035	COG1309	transcriptional regulator
N4T38_01055	COG0351	phosphomethylpyrimidine kinase
N4T38_01055	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N4T38_01055	COG0352	thiamine-phosphate diphosphorylase activity
N4T38_01065	COG2814	Major facilitator Superfamily
N4T38_01080	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N4T38_01090	COG1113	amino acid transport
N4T38_01100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N4T38_01105	COG1012	belongs to the aldehyde dehydrogenase family
N4T38_01115	COG1335	isochorismatase
N4T38_01150	COG2508	Transcriptional regulator
N4T38_01150	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N4T38_01180	COG4372	Transposase
N4T38_01185	COG1113	amino acid transport
N4T38_01195	COG2814	Major facilitator Superfamily
N4T38_01200	COG0583	DNA-binding transcription factor activity
N4T38_01220	COG0667	Aldo Keto reductase
N4T38_01255	COG1733	regulation of RNA biosynthetic process
N4T38_01260	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T38_01325	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N4T38_01340	COG2329	Antibiotic biosynthesis monooxygenase
N4T38_01370	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N4T38_01400	COG0427	acetyl-CoA hydrolase
N4T38_01425	COG0659	secondary active sulfate transmembrane transporter activity
N4T38_01430	COG4221	oxidoreductase activity
N4T38_01440	COG0488	(ABC) transporter
N4T38_01505	COG0833	amino acid
N4T38_01550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N4T38_01555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N4T38_01570	COG2226	methyltransferase
N4T38_01620	COG0069	glutamate synthase activity
N4T38_01620	COG0067	glutamate synthase
N4T38_01620	COG0070	glutamate synthase
N4T38_01625	COG0493	'glutamate synthase
N4T38_01635	COG1704	LemA family
N4T38_01640	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
N4T38_01660	COG3307	-O-antigen
N4T38_01680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N4T38_01695	COG0194	GDP metabolic process
N4T38_01745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N4T38_01765	COG5380	lipid catabolic process
N4T38_01770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N4T38_01795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N4T38_01800	COG0277	FAD linked oxidase domain protein
N4T38_01815	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N4T38_01820	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T38_01845	COG4372	Transposase
N4T38_01855	COG1289	transmembrane transporter activity
N4T38_01865	COG0628	permease
N4T38_01870	COG1192	Involved in chromosome partitioning
N4T38_01900	COG0833	amino acid
N4T38_01905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N4T38_01910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N4T38_01920	COG1012	belongs to the aldehyde dehydrogenase family
N4T38_01960	COG0583	DNA-binding transcription factor activity
N4T38_01980	COG1106	Psort location Cytoplasmic, score
N4T38_02015	COG0517	IMP dehydrogenase activity
N4T38_02020	COG1983	PspC domain protein
N4T38_02030	COG1960	acyl-CoA dehydrogenase activity
N4T38_02045	COG0408	coproporphyrinogen oxidase activity
N4T38_02065	COG0513	Belongs to the DEAD box helicase family
N4T38_02075	COG1127	ABC transporter
N4T38_02080	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N4T38_02090	COG2854	intermembrane phospholipid transfer
N4T38_02100	COG0598	Magnesium transport protein CorA
N4T38_02110	COG0494	nUDIX hydrolase
N4T38_02115	COG1040	competence protein
N4T38_02120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N4T38_02140	COG1946	Acyl-CoA thioesterase
N4T38_02145	COG1301	dicarboxylic acid transport
N4T38_02160	COG1959	2 iron, 2 sulfur cluster binding
N4T38_02165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T38_02165	COG1017	nitric oxide dioxygenase activity
N4T38_02175	COG0433	COG0433 Predicted ATPase
N4T38_02180	COG0626	cystathionine gamma-synthase activity
N4T38_02335	COG1960	acyl-CoA dehydrogenase activity
N4T38_02340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N4T38_02370	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
N4T38_02375	COG0339	signal peptide processing
N4T38_02380	COG0557	exoribonuclease II activity
N4T38_02425	COG0179	Fumarylacetoacetate (FAA) hydrolase
N4T38_02435	COG0697	spore germination
N4T38_02440	COG1295	ribonuclease BN
N4T38_02475	COG1702	phosphate starvation-inducible protein PhoH
N4T38_02485	COG0739	heme binding
N4T38_02485	COG0741	lytic transglycosylase activity
N4T38_02485	COG1196	nuclear chromosome segregation
N4T38_02515	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N4T38_02520	COG1183	phosphatidylcholine synthase activity
N4T38_02565	COG1960	acyl-CoA dehydrogenase activity
N4T38_02570	COG1309	transcriptional regulator
N4T38_02585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N4T38_02590	COG1960	acyl-CoA dehydrogenase activity
N4T38_02610	COG2969	positive regulation of protein catabolic process
N4T38_02620	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N4T38_02635	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N4T38_02640	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N4T38_02660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N4T38_02670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N4T38_02675	COG1408	metallophosphoesterase
N4T38_02685	COG2199	diguanylate cyclase activity
N4T38_02745	COG1607	acyl-coa hydrolase
N4T38_02775	COG2350	Protein conserved in bacteria
N4T38_02785	COG0613	PHP domain protein
N4T38_02790	COG3781	membrane
N4T38_02800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N4T38_02805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N4T38_02815	COG1862	Preprotein translocase
N4T38_02875	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N4T38_02895	COG0726	polysaccharide deacetylase
N4T38_02900	COG0463	Glycosyl transferase, family 2
N4T38_02905	COG0438	transferase activity, transferring glycosyl groups
N4T38_02930	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_02990	COG1960	acyl-CoA dehydrogenase activity
N4T38_02995	COG1960	acyl-CoA dehydrogenase activity
N4T38_03005	COG2205	protein histidine kinase activity
N4T38_03010	COG0745	RESPONSE REGULATOR receiver
N4T38_03015	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N4T38_03030	COG0584	glycerophosphoryl diester phosphodiesterase
N4T38_03035	COG2096	Adenosyltransferase
N4T38_03040	COG4206	TonB-dependent receptor
N4T38_03085	COG0285	dihydrofolate synthase activity
N4T38_03105	COG0450	alkyl hydroperoxide reductase
N4T38_03120	COG0477	Major facilitator Superfamily
N4T38_03125	COG1272	protein, Hemolysin III
N4T38_03155	COG0183	Belongs to the thiolase family
N4T38_03160	COG2207	Transcriptional regulator
N4T38_03180	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N4T38_03200	COG0183	Belongs to the thiolase family
N4T38_03210	COG2885	chlorophyll binding
N4T38_03210	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
N4T38_03220	COG1690	Belongs to the RtcB family
N4T38_03225	COG0833	amino acid
N4T38_03235	COG2233	PERMEase
N4T38_03240	COG1217	gtp-binding protein TYPA
N4T38_03265	COG2094	Belongs to the DNA glycosylase MPG family
N4T38_03270	COG4772	TonB-dependent receptor
N4T38_03275	COG1902	pentaerythritol trinitrate reductase activity
N4T38_03290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N4T38_03295	COG0354	folic acid binding
N4T38_03305	COG3189	MarR family transcriptional regulator
N4T38_03310	COG2824	Alkylphosphonate utilization operon protein PhnA
N4T38_03315	COG3422	double-strand break repair
N4T38_03355	COG0840	transmembrane signaling receptor activity
N4T38_03375	COG5510	response to toxic substance
N4T38_03385	COG2832	Protein of unknown function (DUF454)
N4T38_03390	COG1376	ErfK ybiS ycfS ynhG family protein
N4T38_03430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N4T38_03440	COG1289	transmembrane transporter activity
N4T38_03445	COG2814	Major facilitator Superfamily
N4T38_03465	COG1115	amino acid carrier protein
N4T38_03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
N4T38_03475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N4T38_03480	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
N4T38_03485	COG3590	peptidase
N4T38_03510	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N4T38_03520	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N4T38_03525	COG1077	Cell shape determining protein MreB Mrl
N4T38_03530	COG1792	Involved in formation and maintenance of cell shape
N4T38_03535	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N4T38_03540	COG0424	maF-like protein
N4T38_03545	COG1530	ribonuclease E activity
N4T38_03555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T38_03565	COG0560	Phosphoserine phosphatase
N4T38_03575	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T38_03600	COG2207	Transcriptional regulator
N4T38_03620	COG0464	growth
N4T38_03645	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_03700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N4T38_03710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N4T38_03725	COG0730	response to heat
N4T38_03735	COG1196	nuclear chromosome segregation
N4T38_03755	COG2223	nitrite transmembrane transporter activity
N4T38_03760	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
N4T38_03765	COG1877	trehalose-phosphatase activity
N4T38_03770	COG2226	methyltransferase
N4T38_03770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N4T38_03770	COG0596	Alpha beta hydrolase
N4T38_03785	COG4106	trans-aconitate 2-methyltransferase activity
N4T38_03800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N4T38_03805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N4T38_03810	COG0009	L-threonylcarbamoyladenylate synthase
N4T38_03815	COG3101	peptidyl-lysine hydroxylation
N4T38_03820	COG1399	metal-binding, possibly nucleic acid-binding protein
N4T38_03845	COG1652	LysM domain
N4T38_03850	COG0351	phosphomethylpyrimidine kinase
N4T38_03850	COG0352	thiamine-phosphate diphosphorylase activity
N4T38_03850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N4T38_03860	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N4T38_03890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N4T38_03920	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
N4T38_03935	COG0358	DNA primase activity
N4T38_03945	COG0564	pseudouridine synthase activity
N4T38_03995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T38_04025	COG3620	sequence-specific DNA binding
N4T38_04055	COG0305	Participates in initiation and elongation during chromosome replication
N4T38_04145	COG5410	chromosome segregation
N4T38_04275	COG3561	AntA/AntB antirepressor
N4T38_04285	COG0739	heme binding
N4T38_04365	COG0582	viral genome integration into host DNA
N4T38_04375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N4T38_04395	COG0583	DNA-binding transcription factor activity
N4T38_04400	COG0473	3-isopropylmalate dehydrogenase activity
N4T38_04410	COG0657	acetylesterase activity
N4T38_04420	COG1012	belongs to the aldehyde dehydrogenase family
N4T38_04440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N4T38_04440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N4T38_04455	COG1981	membrane
N4T38_04500	COG0456	acetyltransferase
N4T38_04510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N4T38_04515	COG0492	ferredoxin-NADP+ reductase activity
N4T38_04520	COG1674	ftsk spoiiie
N4T38_04525	COG1280	lysine exporter protein (LysE YggA)
N4T38_04540	COG2894	cell division
N4T38_04555	COG0204	Acyl-transferase
N4T38_04560	COG2885	chlorophyll binding
N4T38_04565	COG0210	DNA helicase
N4T38_04575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N4T38_04590	COG0121	glutamine amidotransferase
N4T38_04610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N4T38_04615	COG0735	belongs to the Fur family
N4T38_04640	COG0420	3'-5' exonuclease activity
N4T38_04660	COG1090	epimerase
N4T38_04675	COG2050	protein possibly involved in aromatic compounds catabolism
N4T38_04685	COG2814	Major facilitator Superfamily
N4T38_04690	COG0405	Gamma-glutamyltransferase
N4T38_04760	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
N4T38_04770	COG0477	Major facilitator Superfamily
N4T38_04775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T38_04785	COG1595	DNA-templated transcription, initiation
N4T38_04840	COG0531	amino acid
N4T38_04870	COG1309	transcriptional regulator
N4T38_04875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N4T38_04880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N4T38_04890	COG1607	acyl-coa hydrolase
N4T38_04900	COG0523	cobalamin synthesis protein
N4T38_04910	COG4681	YaeQ
N4T38_04920	COG1649	PFAM Uncharacterised BCR, COG1649
N4T38_04920	COG0726	polysaccharide deacetylase
N4T38_04925	COG1215	transferase activity, transferring glycosyl groups
N4T38_04935	COG1024	Enoyl-CoA hydratase
N4T38_04950	COG1414	Transcriptional regulator
N4T38_04970	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_04985	COG2271	Major facilitator Superfamily
N4T38_04995	COG2267	carboxylic ester hydrolase activity
N4T38_05000	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_05015	COG0028	Belongs to the TPP enzyme family
N4T38_05025	COG0477	Major facilitator Superfamily
N4T38_05030	COG0242	peptide deformylase activity
N4T38_05035	COG2066	Belongs to the glutaminase family
N4T38_05040	COG2207	Transcriptional regulator
N4T38_05045	COG2223	nitrite transmembrane transporter activity
N4T38_05060	COG0583	DNA-binding transcription factor activity
N4T38_05065	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_05070	COG2271	Major facilitator Superfamily
N4T38_05075	COG3959	Transketolase, thiamine diphosphate binding domain
N4T38_05080	COG3958	Transketolase
N4T38_05090	COG0306	phosphate transporter
N4T38_05110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N4T38_05155	COG4181	ATPase activity
N4T38_05190	COG0583	DNA-binding transcription factor activity
N4T38_05200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N4T38_05205	COG1773	rubredoxin
N4T38_05260	COG2851	Citrate transporter
N4T38_05265	COG1253	flavin adenine dinucleotide binding
N4T38_05310	COG0804	urea catabolic process
N4T38_05320	COG0830	nickel cation binding
N4T38_05335	COG0742	ribosomal rna small subunit methyltransferase
N4T38_05340	COG0768	penicillin binding
N4T38_05365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N4T38_05370	COG2878	Part of a membrane complex involved in electron transport
N4T38_05375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N4T38_05385	COG3384	dioxygenase
N4T38_05415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N4T38_05600	COG5410	chromosome segregation
N4T38_05710	COG1196	nuclear chromosome segregation
N4T38_05710	COG0739	heme binding
N4T38_05710	COG0741	lytic transglycosylase activity
N4T38_05755	COG2194	sulfuric ester hydrolase activity
N4T38_05795	COG0006	proline dipeptidase activity
N4T38_05800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T38_05805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T38_05825	COG1279	arginine transmembrane transporter activity
N4T38_05830	COG0583	DNA-binding transcription factor activity
N4T38_05885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T38_05890	COG0741	lytic transglycosylase activity
N4T38_05890	COG1388	LysM domain
N4T38_05890	COG0741	lytic transglycosylase activity
N4T38_05890	COG1388	LysM domain
N4T38_05900	COG4174	ABC transporter (Permease)
N4T38_05905	COG4239	(ABC) transporter, permease
N4T38_05910	COG4172	Belongs to the ABC transporter superfamily
N4T38_05930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T38_05950	COG0446	pyridine nucleotide-disulphide oxidoreductase
N4T38_05950	COG1902	pentaerythritol trinitrate reductase activity
N4T38_05960	COG0582	viral genome integration into host DNA
N4T38_06000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T38_06015	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N4T38_06060	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
N4T38_06065	COG2072	flavoprotein involved in K transport
N4T38_06070	COG0300	oxidoreductase activity
N4T38_06080	COG1309	transcriptional regulator
N4T38_06085	COG1741	Belongs to the pirin family
N4T38_06100	COG2072	flavoprotein involved in K transport
N4T38_06110	COG2252	PERMEase
N4T38_06115	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N4T38_06120	COG3038	cytochrome b561
N4T38_06130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N4T38_06140	COG0527	aspartate kinase activity
N4T38_06300	COG5410	chromosome segregation
N4T38_06405	COG1598	PFAM Uncharacterised protein family UPF0150
N4T38_06430	COG0739	heme binding
N4T38_06500	COG0582	viral genome integration into host DNA
N4T38_06510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N4T38_06520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N4T38_06535	COG0667	Aldo Keto reductase
N4T38_06550	COG1765	OsmC-like protein
N4T38_06565	COG0542	response to heat
N4T38_06600	COG2885	chlorophyll binding
N4T38_06610	COG0625	glutathione transferase activity
N4T38_06615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N4T38_06635	COG3634	alkyl hydroperoxide reductase activity
N4T38_06645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N4T38_06655	COG0450	alkyl hydroperoxide reductase
N4T38_06660	COG1643	Atp-dependent helicase
N4T38_06675	COG2814	Major facilitator Superfamily
N4T38_06680	COG3135	benzoate transporter
N4T38_06685	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_06690	COG0633	Ferredoxin
N4T38_06690	COG0543	2 iron, 2 sulfur cluster binding
N4T38_06700	COG4638	Rieske (2fe-2S)
N4T38_06710	COG0583	DNA-binding transcription factor activity
N4T38_06720	COG2871	sodium ion transport
N4T38_06805	COG1570	exodeoxyribonuclease VII activity
N4T38_06835	COG1280	lysine exporter protein (LysE YggA)
N4T38_06840	COG1278	Cold shock
N4T38_06880	COG2814	Major facilitator Superfamily
N4T38_06940	COG0210	DNA helicase
N4T38_06950	COG5377	YqaJ viral recombinase family
N4T38_07175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
N4T38_07185	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N4T38_07190	COG1137	ATPase activity
N4T38_07195	COG1538	Outer membrane efflux protein
N4T38_07225	COG4122	O-methyltransferase activity
N4T38_07235	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N4T38_07250	COG1522	sequence-specific DNA binding
N4T38_07255	COG5006	permease, DMT superfamily
N4T38_07265	COG1560	Kdo2-lipid A biosynthetic process
N4T38_07280	COG2814	Major facilitator Superfamily
N4T38_07305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N4T38_07330	COG1250	3-hydroxyacyl-CoA dehydrogenase
N4T38_07375	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_07410	COG0583	DNA-binding transcription factor activity
N4T38_07415	COG1914	H( )-stimulated, divalent metal cation uptake system
N4T38_07435	COG4770	biotin carboxylase activity
N4T38_07440	COG0038	chloride channel
N4T38_07465	COG1063	alcohol dehydrogenase
N4T38_07480	COG0439	Biotin carboxylase
N4T38_07485	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T38_07490	COG1733	regulation of RNA biosynthetic process
N4T38_07500	COG0864	Transcriptional regulator
N4T38_07510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N4T38_07515	COG1116	anion transmembrane transporter activity
N4T38_07635	COG0590	tRNA wobble adenosine to inosine editing
N4T38_07640	COG2807	transmembrane transport
N4T38_07655	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N4T38_07665	COG0789	Transcriptional regulator
N4T38_07675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T38_07695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N4T38_07720	COG1012	belongs to the aldehyde dehydrogenase family
N4T38_07725	COG0531	amino acid
N4T38_07730	COG1760	l-serine dehydratase
N4T38_07735	COG2030	dehydratase
N4T38_07735	COG1012	belongs to the aldehyde dehydrogenase family
N4T38_07740	COG3396	Phenylacetate-CoA oxygenase
N4T38_07745	COG3460	Phenylacetate-CoA oxygenase
N4T38_07750	COG3396	Phenylacetate-CoA oxygenase
N4T38_07755	COG2151	metal-sulfur cluster biosynthetic enzyme
N4T38_07760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T38_07765	COG1024	Enoyl-CoA hydratase
N4T38_07770	COG1024	Enoyl-CoA hydratase
N4T38_07775	COG1250	3-hydroxyacyl-CoA dehydrogenase
N4T38_07780	COG0183	Belongs to the thiolase family
N4T38_07785	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
N4T38_07790	COG3327	negative regulation of DNA-templated transcription, initiation
N4T38_07800	COG2050	protein possibly involved in aromatic compounds catabolism
N4T38_07830	COG0753	catalase activity
N4T38_07835	COG3038	cytochrome b561
N4T38_07855	COG2267	carboxylic ester hydrolase activity
N4T38_07860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T38_07865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N4T38_07870	COG1012	belongs to the aldehyde dehydrogenase family
N4T38_07880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N4T38_07895	COG1012	belongs to the aldehyde dehydrogenase family
N4T38_07900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N4T38_07905	COG0583	DNA-binding transcription factor activity
N4T38_07915	COG1414	Transcriptional regulator
N4T38_07920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T38_07930	COG1840	ABC-type Fe3 transport system, periplasmic component
N4T38_07935	COG3842	ATPase activity
N4T38_07950	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N4T38_07955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N4T38_07960	COG2814	Major facilitator Superfamily
N4T38_07965	COG1960	acyl-CoA dehydrogenase activity
N4T38_07980	COG1024	Enoyl-CoA hydratase
N4T38_07995	COG2192	nodulation
N4T38_08000	COG1280	lysine exporter protein (LysE YggA)
N4T38_08020	COG0183	Belongs to the thiolase family
N4T38_08025	COG1250	3-hydroxyacyl-CoA dehydrogenase
N4T38_08030	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_08035	COG1024	Enoyl-CoA hydratase
N4T38_08040	COG1960	acyl-CoA dehydrogenase activity
N4T38_08045	COG2814	Major facilitator Superfamily
N4T38_08050	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N4T38_08055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N4T38_08065	COG2814	Major facilitator Superfamily
N4T38_08075	COG1960	acyl-CoA dehydrogenase activity
N4T38_08090	COG0583	DNA-binding transcription factor activity
N4T38_08100	COG4770	biotin carboxylase activity
N4T38_08105	COG1024	Enoyl-CoA hydratase
N4T38_08110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N4T38_08115	COG1960	acyl-CoA dehydrogenase activity
N4T38_08120	COG1309	transcriptional regulator
N4T38_08125	COG0318	PFAM AMP-dependent synthetase and ligase
N4T38_08145	COG0583	DNA-binding transcription factor activity
N4T38_08195	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_08215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N4T38_08235	COG2205	protein histidine kinase activity
N4T38_08235	COG0784	Response regulator, receiver
N4T38_08255	COG0765	amino acid transport
N4T38_08260	COG0765	amino acid transport
N4T38_08265	COG1126	abc transporter atp-binding protein
N4T38_08270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N4T38_08275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N4T38_08295	COG1280	lysine exporter protein (LysE YggA)
N4T38_08305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N4T38_08310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N4T38_08315	COG1045	serine acetyltransferase
N4T38_08330	COG0583	DNA-binding transcription factor activity
N4T38_08335	COG0625	glutathione transferase activity
N4T38_08340	COG0625	glutathione transferase activity
N4T38_08345	COG0583	DNA-binding transcription factor activity
N4T38_08355	COG1346	cytolysis
N4T38_08375	COG2814	Major facilitator Superfamily
N4T38_08385	COG0583	DNA-binding transcription factor activity
N4T38_08395	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
N4T38_08400	COG3052	prosthetic group binding
N4T38_08420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N4T38_08440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T38_08450	COG1294	oxidase, subunit
N4T38_08455	COG1271	oxidase subunit
N4T38_08475	COG0477	Major facilitator Superfamily
N4T38_08490	COG4521	taurine ABC transporter
N4T38_08500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N4T38_08505	COG2175	clavaminate synthase activity
N4T38_08515	COG1953	Uracil, thiamine, allantoin
N4T38_08525	COG0583	DNA-binding transcription factor activity
N4T38_08535	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N4T38_08550	COG0640	Transcriptional regulator
N4T38_08555	COG0798	PFAM Bile acid sodium symporter
N4T38_08560	COG0583	DNA-binding transcription factor activity
N4T38_08575	COG3634	alkyl hydroperoxide reductase activity
N4T38_08610	COG1301	dicarboxylic acid transport
N4T38_08615	COG0436	Aminotransferase
N4T38_08625	COG0386	Belongs to the glutathione peroxidase family
N4T38_08640	COG0436	Aminotransferase
N4T38_08665	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N4T38_08690	COG0012	GTP binding
N4T38_08695	COG2011	ABC-type metal ion transport system permease component
N4T38_08700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N4T38_08710	COG1464	Belongs to the NlpA lipoprotein family
N4T38_08740	COG0765	amino acid transport
N4T38_08745	COG0765	amino acid transport
N4T38_08750	COG1126	abc transporter atp-binding protein
N4T38_08760	COG1522	sequence-specific DNA binding
N4T38_08775	COG1309	transcriptional regulator
N4T38_08795	COG0583	DNA-binding transcription factor activity
N4T38_08805	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N4T38_08815	COG0697	spore germination
N4T38_08840	COG3121	Chaperone
N4T38_08845	COG3539	Fimbrial protein
N4T38_08870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N4T38_08870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N4T38_08915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N4T38_08925	COG2353	YceI-like domain
N4T38_08935	COG3698	Phosphodiester glycosidase
N4T38_08950	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N4T38_08955	COG0506	proline dehydrogenase activity
N4T38_08955	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
N4T38_08955	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
N4T38_08965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N4T38_08970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N4T38_08990	COG1132	(ABC) transporter
N4T38_08995	COG3122	Protein conserved in bacteria
N4T38_09000	COG3619	membrane
N4T38_09010	COG0640	Transcriptional regulator
N4T38_09020	COG2850	peptidyl-arginine hydroxylation
N4T38_09025	COG0424	maF-like protein
N4T38_09045	COG0191	fructose-bisphosphate aldolase activity
N4T38_09050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N4T38_09065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N4T38_09075	COG1192	Involved in chromosome partitioning
N4T38_09080	COG1475	DNA binding
N4T38_09085	COG0811	peptide transport
N4T38_09095	COG1132	(ABC) transporter
N4T38_09100	COG1663	tetraacyldisaccharide 4'-kinase activity
N4T38_09120	COG0084	hydrolase, TatD family'
N4T38_09185	COG0776	regulation of translation
N4T38_09215	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
N4T38_09220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N4T38_09270	COG0339	signal peptide processing
N4T38_09280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N4T38_09315	COG0702	epimerase
N4T38_09320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N4T38_09340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N4T38_09370	COG0316	Belongs to the HesB IscA family
N4T38_09375	COG0822	iron-sulfur transferase activity
N4T38_09400	COG0776	regulation of translation
N4T38_09405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N4T38_09410	COG2207	Transcriptional regulator
N4T38_09415	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N4T38_09420	COG1960	acyl-CoA dehydrogenase activity
N4T38_09425	COG1960	acyl-CoA dehydrogenase activity
N4T38_09440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N4T38_09455	COG2814	Major facilitator Superfamily
N4T38_09460	COG4264	IucA IucC family
N4T38_09465	COG4264	IucA IucC family
N4T38_09475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N4T38_09505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N4T38_09525	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N4T38_09530	COG0406	alpha-ribazole phosphatase activity
N4T38_09545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N4T38_09550	COG0730	response to heat
N4T38_09570	COG4773	Receptor
N4T38_09575	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N4T38_09595	COG0842	Transport permease protein
N4T38_09600	COG0842	Transport permease protein
N4T38_09660	COG2226	methyltransferase
N4T38_09685	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N4T38_09720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N4T38_09730	COG0133	tryptophan synthase activity
N4T38_09745	COG3706	GGDEF domain
N4T38_09760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N4T38_09765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N4T38_09770	COG0022	dehydrogenase e1 component
N4T38_09775	COG0508	dehydrogenase complex catalyzes the overall conversion of
N4T38_09790	COG1063	alcohol dehydrogenase
N4T38_09795	COG3781	membrane
N4T38_09805	COG3453	Protein conserved in bacteria
N4T38_09805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N4T38_09820	COG0730	response to heat
N4T38_09835	COG2207	Transcriptional regulator
N4T38_09835	COG3708	Transcriptional regulator
N4T38_09840	COG1733	regulation of RNA biosynthetic process
N4T38_09845	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N4T38_09855	COG2188	Transcriptional regulator
N4T38_09870	COG4521	taurine ABC transporter
N4T38_09875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N4T38_09935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T38_09940	COG0431	NADPH-dependent FMN reductase
N4T38_09965	COG4691	Plasmid stability protein
N4T38_10000	COG0798	PFAM Bile acid sodium symporter
N4T38_10035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N4T38_10050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N4T38_10055	COG1538	Outer membrane efflux protein
N4T38_10060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N4T38_10065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T38_10080	COG4372	Transposase
N4T38_10090	COG2963	transposase activity
N4T38_10115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N4T38_10150	COG0477	Major facilitator Superfamily
N4T38_10160	COG1027	Aspartate ammonia-lyase
N4T38_10175	COG0583	DNA-binding transcription factor activity
N4T38_10180	COG0583	DNA-binding transcription factor activity
N4T38_10185	COG0183	Belongs to the thiolase family
N4T38_10190	COG2031	fatty acid transporter
N4T38_10205	COG0583	DNA-binding transcription factor activity
N4T38_10215	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_10230	COG1309	transcriptional regulator
N4T38_10245	COG2610	gluconate transmembrane transporter activity
N4T38_10250	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_10255	COG2207	Transcriptional regulator
N4T38_10270	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_10280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T38_10295	COG0543	2 iron, 2 sulfur cluster binding
N4T38_10295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T38_10300	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
N4T38_10305	COG4638	Rieske (2fe-2S)
N4T38_10315	COG0725	ABC transporter, periplasmic molybdate-binding protein
N4T38_10320	COG4149	molybdate abc transporter
N4T38_10325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
N4T38_10330	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_10335	COG3433	isochorismatase activity
N4T38_10335	COG1535	isochorismatase
N4T38_10400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N4T38_10415	COG0753	catalase activity
N4T38_10425	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N4T38_10460	COG2205	protein histidine kinase activity
N4T38_10480	COG2814	Major facilitator Superfamily
N4T38_10505	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N4T38_10550	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_10595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N4T38_10615	COG1120	ATPase activity
N4T38_10620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N4T38_10630	COG1064	alcohol dehydrogenase
N4T38_10635	COG2207	Transcriptional regulator
N4T38_10640	COG2084	Dehydrogenase
N4T38_10650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N4T38_10655	COG0583	DNA-binding transcription factor activity
N4T38_10665	COG0129	dihydroxy-acid dehydratase activity
N4T38_10670	COG1012	belongs to the aldehyde dehydrogenase family
N4T38_10675	COG1846	Transcriptional regulator
N4T38_10680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T38_10685	COG1960	acyl-CoA dehydrogenase activity
N4T38_10720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N4T38_10755	COG0583	DNA-binding transcription factor activity
N4T38_10770	COG2188	Transcriptional regulator
N4T38_10850	COG1960	acyl-CoA dehydrogenase activity
N4T38_10855	COG0583	DNA-binding transcription factor activity
N4T38_10860	COG1414	Transcriptional regulator
N4T38_10875	COG2391	methyltransferase activity
N4T38_10880	COG3293	Transposase
N4T38_10890	COG4993	Dehydrogenase
N4T38_10895	COG3659	wide pore channel activity
N4T38_10900	COG3420	alginic acid biosynthetic process
N4T38_10905	COG0710	3-dehydroquinate dehydratase activity
N4T38_10910	COG3485	protocatechuate 3,4-dioxygenase
N4T38_10915	COG3485	protocatechuate 3,4-dioxygenase
N4T38_10920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N4T38_10925	COG2271	Major facilitator Superfamily
N4T38_10930	COG0596	Alpha beta hydrolase
N4T38_10935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N4T38_10940	COG0183	Belongs to the thiolase family
N4T38_10945	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N4T38_10950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N4T38_10960	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N4T38_10965	COG2323	membrane
N4T38_11010	COG0446	pyridine nucleotide-disulphide oxidoreductase
N4T38_11010	COG1902	pentaerythritol trinitrate reductase activity
N4T38_11035	COG0542	response to heat
N4T38_11040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N4T38_11080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N4T38_11085	COG0569	domain protein
N4T38_11090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N4T38_11115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N4T38_11125	COG1585	Membrane protein implicated in regulation of membrane protease activity
N4T38_11145	COG1294	oxidase, subunit
N4T38_11150	COG4890	Cyd operon protein YbgT
N4T38_11165	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
N4T38_11175	COG0552	protein localization to endoplasmic reticulum
N4T38_11200	COG0516	GMP reductase activity
N4T38_11200	COG0517	IMP dehydrogenase activity
N4T38_11205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N4T38_11210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N4T38_11220	COG0583	DNA-binding transcription factor activity
N4T38_11225	COG0024	Methionine aminopeptidase
N4T38_11255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N4T38_11255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N4T38_11260	COG1105	Belongs to the carbohydrate kinase PfkB family
N4T38_11265	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
N4T38_11265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N4T38_11265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N4T38_11285	COG3300	MHYT domain
N4T38_11285	COG5001	Diguanylate cyclase
N4T38_11300	COG2135	peptidase activity
N4T38_11305	COG0659	secondary active sulfate transmembrane transporter activity
N4T38_11325	COG1113	amino acid transport
N4T38_11335	COG1522	sequence-specific DNA binding
N4T38_11360	COG1011	Hydrolase
N4T38_11365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N4T38_11375	COG2137	regulation of response to DNA damage stimulus
N4T38_11390	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N4T38_11425	COG0575	Belongs to the CDS family
N4T38_11430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N4T38_11455	COG3852	Histidine kinase
N4T38_11460	COG2204	response regulator
N4T38_11515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N4T38_11520	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
N4T38_11540	COG0697	spore germination
N4T38_11545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T38_11555	COG0303	'Molybdopterin
N4T38_11560	COG0521	Mo-molybdopterin cofactor biosynthetic process
N4T38_11560	COG0315	cyclic pyranopterin monophosphate synthase activity
N4T38_11575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N4T38_11580	COG0243	molybdopterin cofactor binding
N4T38_11590	COG0243	molybdopterin cofactor binding
N4T38_11595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N4T38_11600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N4T38_11600	COG2146	nitrite reductase [NAD(P)H] activity
N4T38_11610	COG0745	RESPONSE REGULATOR receiver
N4T38_11615	COG1116	anion transmembrane transporter activity
N4T38_11615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N4T38_11630	COG0511	ligase activity, forming carbon-carbon bonds
N4T38_11645	COG2814	Major facilitator Superfamily
N4T38_11665	COG0069	glutamate synthase activity
N4T38_11685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N4T38_11695	COG1454	alcohol dehydrogenase
N4T38_11700	COG0824	Thioesterase
N4T38_11725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N4T38_11730	COG2030	dehydratase
N4T38_11740	COG0183	Belongs to the thiolase family
N4T38_11750	COG0583	DNA-binding transcription factor activity
N4T38_11755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N4T38_11765	COG1522	sequence-specific DNA binding
N4T38_11770	COG3135	benzoate transporter
N4T38_11810	COG0589	response to stress
N4T38_11815	COG0488	(ABC) transporter
N4T38_11835	COG4773	Receptor
N4T38_11865	COG0668	transmembrane transport
N4T38_11875	COG1309	transcriptional regulator
N4T38_11895	COG1605	Chorismate mutase
N4T38_11915	COG0308	aminopeptidase N
N4T38_11940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N4T38_11945	COG1454	alcohol dehydrogenase
N4T38_11965	COG0531	amino acid
N4T38_11970	COG4303	Ethanolamine ammonia lyase large subunit
N4T38_11975	COG4302	ethanolamine ammonia-lyase activity
N4T38_11980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N4T38_11980	COG0519	Catalyzes the synthesis of GMP from XMP
N4T38_11985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N4T38_12010	COG0697	spore germination
N4T38_12015	COG1923	regulation of RNA biosynthetic process
N4T38_12025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N4T38_12030	COG0802	atpase or kinase
N4T38_12050	COG1187	pseudouridine synthase activity
N4T38_12065	COG0583	DNA-binding transcription factor activity
N4T38_12080	COG2814	Major facilitator Superfamily
N4T38_12085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N4T38_12110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N4T38_12165	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_12175	COG2963	transposase activity
N4T38_12185	COG4372	Transposase
N4T38_12215	COG0592	DNA-directed DNA polymerase activity
N4T38_12255	COG2026	Addiction module toxin, RelE StbE family
N4T38_12475	COG1484	DNA-dependent DNA replication
N4T38_12570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T38_12610	COG0729	surface antigen
N4T38_12630	COG0174	glutamine synthetase
N4T38_12635	COG0745	RESPONSE REGULATOR receiver
N4T38_12640	COG2205	protein histidine kinase activity
N4T38_12650	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
N4T38_12655	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
N4T38_12680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T38_12685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N4T38_12690	COG1960	acyl-CoA dehydrogenase activity
N4T38_12720	COG0583	DNA-binding transcription factor activity
N4T38_12735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N4T38_12745	COG3658	cytochrome
N4T38_12750	COG1215	transferase activity, transferring glycosyl groups
N4T38_12755	COG0726	polysaccharide deacetylase
N4T38_12755	COG1649	PFAM Uncharacterised BCR, COG1649
N4T38_12780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N4T38_12785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N4T38_12795	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N4T38_12820	COG0305	Participates in initiation and elongation during chromosome replication
N4T38_12825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N4T38_12835	COG1305	Transglutaminase-like
N4T38_12845	COG2308	Evidence 4 Homologs of previously reported genes of
N4T38_12875	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
N4T38_12880	COG0138	bifunctional purine biosynthesis protein purh
N4T38_12885	COG0151	Belongs to the GarS family
N4T38_12890	COG1464	Belongs to the NlpA lipoprotein family
N4T38_12895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N4T38_12900	COG2011	ABC-type metal ion transport system permease component
N4T38_12905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N4T38_12915	COG1301	dicarboxylic acid transport
N4T38_12950	COG1794	racemase activity, acting on amino acids and derivatives
N4T38_12960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N4T38_12960	COG3008	intermembrane lipid transfer
N4T38_12965	COG2995	paraquat-inducible protein a
N4T38_12975	COG2985	domain, Protein
N4T38_12990	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_13010	COG0477	Major facilitator Superfamily
N4T38_13060	COG2186	Transcriptional regulator
N4T38_13070	COG0786	glutamate:sodium symporter activity
N4T38_13075	COG3243	poly(R)-hydroxyalkanoic acid synthase
N4T38_13100	COG3111	PFAM Bacterial OB fold (BOF) protein
N4T38_13180	COG3210	domain, Protein
N4T38_13180	COG3210	domain, Protein
N4T38_13185	COG2831	hemolysin activation secretion protein
N4T38_13240	COG1610	YqeY-like protein
N4T38_13270	COG1286	toxin biosynthetic process
N4T38_13300	COG0778	Nitroreductase
N4T38_13310	COG0513	Belongs to the DEAD box helicase family
N4T38_13335	COG2363	Small membrane protein
N4T38_13365	COG1234	tRNA 3'-trailer cleavage
N4T38_13370	COG2195	Cleaves the N-terminal amino acid of tripeptides
N4T38_13380	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N4T38_13390	COG2819	hydrolase of the alpha beta superfamily
N4T38_13395	COG1960	acyl-CoA dehydrogenase activity
N4T38_13400	COG1301	dicarboxylic acid transport
N4T38_13405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N4T38_13410	COG3139	Protein of unknown function (DUF1315)
N4T38_13415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N4T38_13420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N4T38_13430	COG0494	nUDIX hydrolase
N4T38_13440	COG0642	Histidine kinase
N4T38_13455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N4T38_13465	COG1720	tRNA m6t6A37 methyltransferase activity
N4T38_13480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T38_13485	COG0826	peptidase U32
N4T38_13490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N4T38_13500	COG4598	ABC transporter
N4T38_13505	COG4160	amino acid transport
N4T38_13510	COG4215	(ABC) transporter
N4T38_13535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T38_13655	COG0739	heme binding
N4T38_13970	COG0582	viral genome integration into host DNA
N4T38_13975	COG1131	(ABC) transporter
N4T38_13980	COG0842	Transport permease protein
N4T38_13995	COG0772	Belongs to the SEDS family
N4T38_14000	COG2951	lytic endotransglycosylase activity
N4T38_14025	COG2207	Transcriptional regulator
N4T38_14040	COG0052	Belongs to the universal ribosomal protein uS2 family
N4T38_14045	COG0024	Methionine aminopeptidase
N4T38_14055	COG2223	nitrite transmembrane transporter activity
N4T38_14065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N4T38_14070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N4T38_14075	COG1960	acyl-CoA dehydrogenase activity
N4T38_14090	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
N4T38_14095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N4T38_14100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N4T38_14130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N4T38_14135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N4T38_14140	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N4T38_14175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N4T38_14185	COG0174	glutamine synthetase
N4T38_14200	COG0582	viral genome integration into host DNA
N4T38_14275	COG1598	PFAM Uncharacterised protein family UPF0150
N4T38_14395	COG5410	chromosome segregation
N4T38_14570	COG0512	Glutamine amidotransferase of anthranilate synthase
N4T38_14605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N4T38_14615	COG0302	gtp cyclohydrolase
N4T38_14640	COG3739	integral membrane protein
N4T38_14655	COG1169	isochorismate synthase
N4T38_14665	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N4T38_14670	COG1132	(ABC) transporter
N4T38_14675	COG1132	(ABC) transporter
N4T38_14685	COG1535	isochorismatase
N4T38_14685	COG3433	isochorismatase activity
N4T38_14690	COG1021	2,3-dihydroxybenzoate-AMP ligase
N4T38_14695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T38_14705	COG4774	siderophore transport
N4T38_14710	COG4607	ABC-type enterochelin transport system periplasmic component
N4T38_14715	COG4604	ABC transporter, ATP-binding protein
N4T38_14720	COG4605	iron ion homeostasis
N4T38_14725	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N4T38_14730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T38_14745	COG2964	Protein conserved in bacteria
N4T38_14755	COG1741	Belongs to the pirin family
N4T38_14775	COG2879	small protein
N4T38_14780	COG1966	Carbon starvation protein
N4T38_14800	COG4943	cyclic-guanylate-specific phosphodiesterase activity
N4T38_14820	COG2211	Major facilitator Superfamily
N4T38_14825	COG1067	ATP-dependent peptidase activity
N4T38_14830	COG0583	DNA-binding transcription factor activity
N4T38_14855	COG1686	Belongs to the peptidase S11 family
N4T38_14860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N4T38_14895	COG0616	signal peptide processing
N4T38_14900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N4T38_14910	COG0573	inorganic phosphate transmembrane transporter activity
N4T38_14915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N4T38_14920	COG1113	amino acid transport
N4T38_14925	COG3961	Belongs to the TPP enzyme family
N4T38_14930	COG1522	sequence-specific DNA binding
N4T38_14940	COG0076	glutamate decarboxylase activity
N4T38_14945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N4T38_14955	COG1309	transcriptional regulator
N4T38_14970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T38_15005	COG0352	thiamine-phosphate diphosphorylase activity
N4T38_15030	COG0612	Peptidase, M16
N4T38_15040	COG1823	symporter activity
N4T38_15045	COG0583	DNA-binding transcription factor activity
N4T38_15050	COG0477	Major facilitator Superfamily
N4T38_15075	COG1187	pseudouridine synthase activity
N4T38_15090	COG1686	Belongs to the peptidase S11 family
N4T38_15095	COG1252	NADH dehydrogenase
N4T38_15105	COG0415	Belongs to the DNA photolyase family
N4T38_15120	COG1215	transferase activity, transferring glycosyl groups
N4T38_15150	COG2070	2-Nitropropane dioxygenase
N4T38_15205	COG0556	nucleotide-excision repair
N4T38_15215	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_15230	COG0436	Aminotransferase
N4T38_15270	COG4221	oxidoreductase activity
N4T38_15280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N4T38_15285	COG1381	Involved in DNA repair and RecF pathway recombination
N4T38_15295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N4T38_15310	COG0681	Belongs to the peptidase S26 family
N4T38_15325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N4T38_15345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N4T38_15350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N4T38_15355	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N4T38_15365	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N4T38_15370	COG4208	sulfate ABC transporter
N4T38_15375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N4T38_15380	COG0583	DNA-binding transcription factor activity
N4T38_15385	COG4625	pathogenesis
N4T38_15400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N4T38_15415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N4T38_15425	COG1051	belongs to the nudix hydrolase family
N4T38_15425	COG1056	cytidyltransferase-related domain
N4T38_15430	COG1024	Enoyl-CoA hydratase
N4T38_15445	COG2814	Major facilitator Superfamily
N4T38_15450	COG0047	phosphoribosylformylglycinamidine synthase activity
N4T38_15450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N4T38_15470	COG1473	amidohydrolase
N4T38_15475	COG0824	Thioesterase
N4T38_15495	COG0823	Involved in the tonB-independent uptake of proteins
N4T38_15515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N4T38_15550	COG0628	permease
N4T38_15560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N4T38_15565	COG0596	Alpha beta hydrolase
N4T38_15570	COG0616	signal peptide processing
N4T38_15570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N4T38_15580	COG0658	competence protein
N4T38_15580	COG2333	competence protein COMEC
N4T38_15585	COG1136	(ABC) transporter
N4T38_15590	COG4591	ABC-type transport system involved in lipoprotein release permease component
N4T38_15625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T38_15645	COG0463	Glycosyl transferase, family 2
N4T38_15675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N4T38_15680	COG1280	lysine exporter protein (LysE YggA)
N4T38_15690	COG0019	diaminopimelate decarboxylase activity
N4T38_15700	COG1113	amino acid transport
N4T38_15715	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
N4T38_15725	COG3339	Conserved Protein
N4T38_15730	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N4T38_15735	COG0243	molybdopterin cofactor binding
N4T38_15740	COG1929	Belongs to the glycerate kinase type-1 family
N4T38_15755	COG0778	Nitroreductase
N4T38_15800	COG3811	Belongs to the UPF0386 family
N4T38_15810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T38_15835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N4T38_15855	COG0741	lytic transglycosylase activity
N4T38_15875	COG0584	glycerophosphoryl diester phosphodiesterase
N4T38_15905	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N4T38_15910	COG1597	lipid kinase activity
N4T38_15925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N4T38_15930	COG0477	Major facilitator Superfamily
N4T38_15980	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N4T38_15985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N4T38_16010	COG0505	Belongs to the CarA family
N4T38_16030	COG0589	response to stress
N4T38_16045	COG2843	Capsule synthesis protein
N4T38_16065	COG2321	neutral zinc metallopeptidase
N4T38_16070	COG2354	Protein conserved in bacteria
N4T38_16090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N4T38_16115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N4T38_16120	COG1053	succinate dehydrogenase
N4T38_16125	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
N4T38_16130	COG2009	succinate dehydrogenase
N4T38_16165	COG2921	Belongs to the UPF0250 family
N4T38_16170	COG0321	lipoyl(octanoyl) transferase activity
N4T38_16185	COG0531	amino acid
N4T38_16195	COG1733	regulation of RNA biosynthetic process
N4T38_16200	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N4T38_16205	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N4T38_16205	COG1648	precorrin-2 dehydrogenase activity
N4T38_16220	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N4T38_16245	COG0215	cysteine-tRNA ligase activity
N4T38_16250	COG0671	phosphoesterase, PA-phosphatase related
N4T38_16255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T38_16265	COG1538	Outer membrane efflux protein
N4T38_16270	COG0393	Putative heavy-metal-binding
N4T38_16275	COG0393	Putative heavy-metal-binding
N4T38_16285	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_16295	COG0525	valine-tRNA ligase activity
N4T38_16320	COG0004	ammonium transporteR
N4T38_16330	COG0642	Histidine kinase
N4T38_16335	COG0745	RESPONSE REGULATOR receiver
N4T38_16340	COG2194	sulfuric ester hydrolase activity
N4T38_16360	COG1752	Esterase of the alpha-beta hydrolase superfamily
N4T38_16375	COG2315	Protein conserved in bacteria
N4T38_16380	COG0142	geranyltranstransferase activity
N4T38_16385	COG2828	Protein conserved in bacteria
N4T38_16390	COG1113	amino acid transport
N4T38_16400	COG0582	viral genome integration into host DNA
N4T38_16440	COG0305	Participates in initiation and elongation during chromosome replication
N4T38_16490	COG0489	protein tyrosine kinase activity
N4T38_16500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N4T38_16500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N4T38_16530	COG2515	1-aminocyclopropane-1-carboxylate deaminase
N4T38_16535	COG2081	HI0933 family
N4T38_16545	COG0668	transmembrane transport
N4T38_16565	COG0583	DNA-binding transcription factor activity
N4T38_16585	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N4T38_16590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N4T38_16620	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N4T38_16660	COG0745	RESPONSE REGULATOR receiver
N4T38_16680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N4T38_16690	COG0384	phenazine biosynthesis protein PhzF
N4T38_16750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T38_16780	COG0583	DNA-binding transcription factor activity
N4T38_16795	COG0583	DNA-binding transcription factor activity
N4T38_16800	COG1053	succinate dehydrogenase
N4T38_16810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N4T38_16815	COG2814	Major facilitator Superfamily
N4T38_16820	COG1960	acyl-CoA dehydrogenase activity
N4T38_16825	COG0583	DNA-binding transcription factor activity
N4T38_16830	COG1063	alcohol dehydrogenase
N4T38_16860	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N4T38_16865	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N4T38_16870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N4T38_16890	COG2132	Multicopper oxidase
N4T38_16900	COG0561	phosphatase activity
N4T38_16905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N4T38_16915	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
N4T38_16930	COG1214	PFAM Peptidase M22, glycoprotease
N4T38_16990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N4T38_16995	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N4T38_17000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N4T38_17060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N4T38_17070	COG1846	Transcriptional regulator
N4T38_17075	COG1764	response to oxidative stress
N4T38_17115	COG0037	tRNA processing
N4T38_17125	COG0248	Ppx GppA phosphatase
N4T38_17155	COG0072	phenylalanine-tRNA ligase activity
N4T38_17195	COG1238	metal cluster binding
N4T38_17200	COG0625	glutathione transferase activity
N4T38_17215	COG0318	PFAM AMP-dependent synthetase and ligase
N4T38_17220	COG3028	Belongs to the UPF0307 family
N4T38_17225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N4T38_17245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N4T38_17250	COG0617	tRNA 3'-terminal CCA addition
N4T38_17255	COG1555	photosystem II stabilization
N4T38_17260	COG3956	TIGRFAM MazG family protein
N4T38_17270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N4T38_17290	COG0784	Response regulator, receiver
N4T38_17290	COG2205	protein histidine kinase activity
N4T38_17290	COG5002	protein histidine kinase activity
N4T38_17295	COG1024	Enoyl-CoA hydratase
N4T38_17300	COG2084	Dehydrogenase
N4T38_17305	COG3622	Belongs to the hyi family
N4T38_17335	COG0697	spore germination
N4T38_17345	COG2814	Major facilitator Superfamily
N4T38_17350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N4T38_17360	COG0583	DNA-binding transcription factor activity
N4T38_17370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N4T38_17385	COG0084	hydrolase, TatD family'
N4T38_17400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N4T38_17410	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_17420	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_17445	COG0440	acetolactate synthase activity
N4T38_17450	COG0028	Belongs to the TPP enzyme family
N4T38_17475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T38_17480	COG0577	efflux transmembrane transporter activity
N4T38_17480	COG1136	(ABC) transporter
N4T38_17485	COG1538	Outer membrane efflux protein
N4T38_17500	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
N4T38_17505	COG1162	GTPase activity
N4T38_17515	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N4T38_17555	COG1426	Protein conserved in bacteria
N4T38_17590	COG0793	Belongs to the peptidase S41A family
N4T38_17605	COG2267	carboxylic ester hydrolase activity
N4T38_17615	COG1012	belongs to the aldehyde dehydrogenase family
N4T38_17620	COG3265	gluconokinase activity
N4T38_17630	COG0800	Aldolase
N4T38_17640	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N4T38_17645	COG0857	belongs to the CobB CobQ family
N4T38_17645	COG0280	phosphate acetyltransferase
N4T38_17650	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
N4T38_17650	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
N4T38_17670	COG0740	serine-type endopeptidase activity
N4T38_17680	COG4774	siderophore transport
N4T38_17690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N4T38_17700	COG2813	Specifically methylates the guanine in position
N4T38_17700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N4T38_17800	COG0788	formyltetrahydrofolate deformylase activity
N4T38_17825	COG4651	solute:proton antiporter activity
N4T38_17825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N4T38_17845	COG0724	RNA recognition motif
N4T38_17850	COG0210	DNA helicase
N4T38_17875	COG1733	regulation of RNA biosynthetic process
N4T38_17885	COG2900	Belongs to the SlyX family
N4T38_17890	COG0488	(ABC) transporter
N4T38_17895	COG1280	lysine exporter protein (LysE YggA)
N4T38_17900	COG1560	Kdo2-lipid A biosynthetic process
N4T38_17910	COG1301	dicarboxylic acid transport
N4T38_17965	COG0473	3-isopropylmalate dehydrogenase activity
N4T38_18030	COG0583	DNA-binding transcription factor activity
N4T38_18040	COG0625	glutathione transferase activity
N4T38_18045	COG2378	regulation of single-species biofilm formation
N4T38_18050	COG0546	phosphoglycolate phosphatase activity
N4T38_18060	COG1530	ribonuclease E activity
N4T38_18065	COG0318	PFAM AMP-dependent synthetase and ligase
N4T38_18080	COG0583	DNA-binding transcription factor activity
N4T38_18085	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_18090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N4T38_18100	COG0534	Mate efflux family protein
N4T38_18115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N4T38_18145	COG0493	'glutamate synthase
N4T38_18145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
N4T38_18155	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
N4T38_18160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N4T38_18175	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N4T38_18185	COG0644	oxidoreductase
N4T38_18185	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
N4T38_18190	COG0425	Belongs to the sulfur carrier protein TusA family
N4T38_18195	COG4535	Mg2 and Co2 transporter CorC
N4T38_18205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N4T38_18225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N4T38_18230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N4T38_18230	COG0475	glutathione-regulated potassium exporter activity
N4T38_18245	COG0484	heat shock protein binding
N4T38_18250	COG0789	Transcriptional regulator
N4T38_18255	COG0598	Magnesium transport protein CorA
N4T38_18270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N4T38_18275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N4T38_18280	COG1074	ATP-dependent DNA helicase activity
N4T38_18285	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
N4T38_18305	COG2226	methyltransferase
N4T38_18315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N4T38_18325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N4T38_18340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N4T38_18340	COG2111	Na H antiporter
N4T38_18345	COG1006	Multisubunit Na H antiporter MnhC subunit
N4T38_18350	COG0651	ATP synthesis coupled electron transport
N4T38_18355	COG1863	multisubunit Na H antiporter MnhE subunit
N4T38_18360	COG2212	antiporter activity
N4T38_18365	COG1320	monovalent cation:proton antiporter activity
N4T38_18380	COG0195	Participates in both transcription termination and antitermination
N4T38_18430	COG0237	dephospho-CoA kinase activity
N4T38_18440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N4T38_18455	COG0497	DNA recombination
N4T38_18465	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N4T38_18495	COG2169	Transcriptional regulator
N4T38_18495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N4T38_18500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N4T38_18530	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_18580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N4T38_18595	COG0326	Molecular chaperone. Has ATPase activity
N4T38_18610	COG2056	Na+-H+ antiporter family
N4T38_18615	COG0596	Alpha beta hydrolase
N4T38_18715	COG0546	phosphoglycolate phosphatase activity
N4T38_18720	COG1716	ATPase activity
N4T38_18765	COG0181	hydroxymethylbilane synthase activity
N4T38_18775	COG3275	phosphorelay sensor kinase activity
N4T38_18795	COG1538	Outer membrane efflux protein
N4T38_18800	COG0697	spore germination
N4T38_18825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N4T38_18830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N4T38_18835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N4T38_18840	COG0772	Belongs to the SEDS family
N4T38_18865	COG4974	Belongs to the 'phage' integrase family
N4T38_18870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N4T38_18880	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N4T38_18890	COG2197	response regulator
N4T38_18905	COG0793	Belongs to the peptidase S41A family
N4T38_18910	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N4T38_18915	COG0795	lipopolysaccharide-transporting ATPase activity
N4T38_18955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N4T38_18955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N4T38_18965	COG0004	ammonium transporteR
N4T38_18970	COG0347	Belongs to the P(II) protein family
N4T38_18990	COG0659	secondary active sulfate transmembrane transporter activity
N4T38_18995	COG0589	response to stress
N4T38_19040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T38_19050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T38_19075	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N4T38_19090	COG0318	PFAM AMP-dependent synthetase and ligase
N4T38_19100	COG0477	Major facilitator Superfamily
N4T38_19105	COG2860	membrane
N4T38_19115	COG1253	flavin adenine dinucleotide binding
N4T38_19135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N4T38_19175	COG0655	NAD(P)H dehydrogenase (quinone) activity
N4T38_19185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N4T38_19255	COG0758	DNA mediated transformation
N4T38_19265	COG0697	spore germination
N4T38_19270	COG1309	transcriptional regulator
N4T38_19285	COG0386	Belongs to the glutathione peroxidase family
N4T38_19350	COG1121	(ABC) transporter
N4T38_19355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N4T38_19360	COG1280	lysine exporter protein (LysE YggA)
N4T38_19365	COG2837	iron assimilation
N4T38_19375	COG0281	malic enzyme
N4T38_19420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N4T38_19420	COG0519	Catalyzes the synthesis of GMP from XMP
N4T38_19425	COG4399	Belongs to the UPF0754 family
N4T38_19430	COG2259	Doxx family
N4T38_19435	COG0586	Pfam SNARE associated Golgi protein
N4T38_19450	COG1192	Involved in chromosome partitioning
N4T38_19460	COG0271	Belongs to the BolA IbaG family
N4T38_19480	COG2267	carboxylic ester hydrolase activity
N4T38_19500	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N4T38_19500	COG3321	synthase
N4T38_19500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N4T38_19500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N4T38_19505	COG1960	acyl-CoA dehydrogenase activity
N4T38_19515	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_19520	COG2197	response regulator
N4T38_19530	COG3916	Acyl-homoserine-lactone synthase
N4T38_19535	COG0477	Major facilitator Superfamily
N4T38_19540	COG1024	Enoyl-CoA hydratase
N4T38_19545	COG1024	Enoyl-CoA hydratase
N4T38_19550	COG1960	acyl-CoA dehydrogenase activity
N4T38_19555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N4T38_19575	COG1113	amino acid transport
N4T38_19580	COG1113	amino acid transport
N4T38_19585	COG0251	oxidation-reduction process
N4T38_19625	COG0564	pseudouridine synthase activity
N4T38_19685	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N4T38_19700	COG1802	Transcriptional regulator
N4T38_19710	COG1448	Aminotransferase
N4T38_19715	COG0277	FAD linked oxidase domain protein
N4T38_19725	COG2186	Transcriptional regulator
N4T38_19735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N4T38_19740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N4T38_19755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N4T38_19760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N4T38_19765	COG1216	Glycosyl transferase, family 2
N4T38_19795	COG2089	acid synthase
N4T38_19810	COG1083	cytidylyl-transferase
N4T38_19815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N4T38_19820	COG1086	Polysaccharide biosynthesis protein
N4T38_19825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
N4T38_19830	COG1596	polysaccharide export
N4T38_19855	COG0728	peptidoglycan biosynthetic process
N4T38_19860	COG3023	N-Acetylmuramoyl-L-alanine amidase
N4T38_19920	COG0546	phosphoglycolate phosphatase activity
N4T38_19925	COG1028	Short-chain dehydrogenase reductase Sdr
N4T38_19945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N4T38_19950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N4T38_19955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N4T38_19960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N4T38_19965	COG1116	anion transmembrane transporter activity
N4T38_19970	COG1309	transcriptional regulator
N4T38_19975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N4T38_19985	COG0196	riboflavin kinase activity
N4T38_19990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N4T38_20000	COG1047	Peptidyl-prolyl cis-trans
N4T38_20040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N4T38_20045	COG0657	acetylesterase activity
N4T38_20065	COG0583	DNA-binding transcription factor activity
N4T38_20095	COG2951	lytic endotransglycosylase activity
N4T38_20100	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N4T38_20115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N4T38_20125	COG0671	phosphoesterase, PA-phosphatase related
N4T38_20130	COG0861	Integral membrane protein TerC family
N4T38_20140	COG0754	glutathionylspermidine amidase activity
N4T38_20150	COG0402	S-adenosylhomocysteine deaminase activity
N4T38_20165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N4T38_20170	COG1230	cation diffusion facilitator family transporter
N4T38_20185	COG0706	membrane insertase activity
N4T38_20460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T38_20465	COG1230	cation diffusion facilitator family transporter
N4T38_20475	COG0640	Transcriptional regulator
N4T38_20485	COG0789	Transcriptional regulator
N4T38_20595	COG1192	Involved in chromosome partitioning
N4T38_20600	COG1475	DNA binding
N4T38_20715	COG4974	Belongs to the 'phage' integrase family
N4T38_20840	COG0657	acetylesterase activity
N4T38_20865	COG2814	Major facilitator Superfamily
N4T38_20875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N4T38_20900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N4T38_20930	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_20935	COG3657	addiction module killer protein
N4T38_20940	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N4T38_20960	COG0488	(ABC) transporter
N4T38_20965	COG3173	Aminoglycoside phosphotransferase
N4T38_21110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N4T38_21185	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_21265	COG2826	transposase and inactivated derivatives, IS30 family
N4T38_21385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N4T38_21440	COG1525	nuclease
N4T38_21450	COG2189	Belongs to the N(4) N(6)-methyltransferase family
N4T38_21470	COG4372	Transposase
N4T38_21530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N4T38_21610	COG4372	Transposase
N4T38_21635	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N4T38_21660	COG0860	N-Acetylmuramoyl-L-alanine amidase
N4T38_21690	COG0745	RESPONSE REGULATOR receiver
N4T38_21695	COG5002	protein histidine kinase activity
N4T38_21705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N4T38_21725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N4T38_21740	COG4372	Transposase
N4T38_21750	COG2963	transposase activity
N4T38_21775	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N4T38_21785	COG4372	Transposase